-- dump date   	20140619_073301
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1104326000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1104326000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1104326000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326000004	Walker A motif; other site
1104326000005	ATP binding site [chemical binding]; other site
1104326000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1104326000007	Walker B motif; other site
1104326000008	arginine finger; other site
1104326000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1104326000010	DnaA box-binding interface [nucleotide binding]; other site
1104326000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1104326000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1104326000013	putative DNA binding surface [nucleotide binding]; other site
1104326000014	dimer interface [polypeptide binding]; other site
1104326000015	beta-clamp/clamp loader binding surface; other site
1104326000016	beta-clamp/translesion DNA polymerase binding surface; other site
1104326000017	recF protein; Region: recf; TIGR00611
1104326000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326000019	Walker A/P-loop; other site
1104326000020	ATP binding site [chemical binding]; other site
1104326000021	Q-loop/lid; other site
1104326000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326000023	ABC transporter signature motif; other site
1104326000024	Walker B; other site
1104326000025	D-loop; other site
1104326000026	H-loop/switch region; other site
1104326000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1104326000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326000029	Mg2+ binding site [ion binding]; other site
1104326000030	G-X-G motif; other site
1104326000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1104326000032	anchoring element; other site
1104326000033	dimer interface [polypeptide binding]; other site
1104326000034	ATP binding site [chemical binding]; other site
1104326000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1104326000036	active site
1104326000037	putative metal-binding site [ion binding]; other site
1104326000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1104326000039	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326000040	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326000041	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475
1104326000042	putative effector binding pocket; other site
1104326000043	putative dimerization interface [polypeptide binding]; other site
1104326000044	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276
1104326000045	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1104326000046	putative NAD(P) binding site [chemical binding]; other site
1104326000047	sugar phosphate phosphatase; Provisional; Region: PRK10513
1104326000048	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326000049	active site
1104326000050	motif I; other site
1104326000051	motif II; other site
1104326000052	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326000053	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1104326000054	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326000055	DNA-binding site [nucleotide binding]; DNA binding site
1104326000056	FCD domain; Region: FCD; pfam07729
1104326000057	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1104326000058	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1104326000059	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1104326000060	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1104326000061	active site
1104326000062	intersubunit interface [polypeptide binding]; other site
1104326000063	catalytic residue [active]
1104326000064	galactonate dehydratase; Provisional; Region: PRK14017
1104326000065	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1104326000066	putative active site pocket [active]
1104326000067	putative metal binding site [ion binding]; other site
1104326000068	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000069	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326000070	putative substrate translocation pore; other site
1104326000071	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1104326000072	hypothetical protein; Provisional; Region: PRK11616
1104326000073	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1104326000074	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1104326000075	putative dimer interface [polypeptide binding]; other site
1104326000076	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1104326000077	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1104326000078	putative dimer interface [polypeptide binding]; other site
1104326000079	putative transporter; Validated; Region: PRK03818
1104326000080	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1104326000081	TrkA-C domain; Region: TrkA_C; pfam02080
1104326000082	TrkA-C domain; Region: TrkA_C; pfam02080
1104326000083	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1104326000084	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1104326000085	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326000086	DNA-binding site [nucleotide binding]; DNA binding site
1104326000087	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1104326000088	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
1104326000089	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1104326000090	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326000091	active site turn [active]
1104326000092	phosphorylation site [posttranslational modification]
1104326000093	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1104326000094	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1104326000095	NAD binding site [chemical binding]; other site
1104326000096	sugar binding site [chemical binding]; other site
1104326000097	divalent metal binding site [ion binding]; other site
1104326000098	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1104326000099	dimer interface [polypeptide binding]; other site
1104326000100	Predicted membrane protein [Function unknown]; Region: COG2149
1104326000101	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1104326000102	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1104326000103	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1104326000104	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326000105	catalytic residue [active]
1104326000106	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1104326000107	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1104326000108	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326000109	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1104326000110	dimerization interface [polypeptide binding]; other site
1104326000111	substrate binding pocket [chemical binding]; other site
1104326000112	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1104326000113	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1104326000114	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000115	putative substrate translocation pore; other site
1104326000116	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1104326000117	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1104326000118	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1104326000119	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326000120	Coenzyme A binding pocket [chemical binding]; other site
1104326000121	Protein of unknown function (DUF796); Region: DUF796; cl01226
1104326000122	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1104326000123	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326000124	PYR/PP interface [polypeptide binding]; other site
1104326000125	dimer interface [polypeptide binding]; other site
1104326000126	TPP binding site [chemical binding]; other site
1104326000127	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326000128	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1104326000129	TPP-binding site [chemical binding]; other site
1104326000130	dimer interface [polypeptide binding]; other site
1104326000131	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1104326000132	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1104326000133	putative valine binding site [chemical binding]; other site
1104326000134	dimer interface [polypeptide binding]; other site
1104326000135	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1104326000136	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326000137	active site
1104326000138	phosphorylation site [posttranslational modification]
1104326000139	intermolecular recognition site; other site
1104326000140	dimerization interface [polypeptide binding]; other site
1104326000141	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326000142	DNA binding residues [nucleotide binding]
1104326000143	dimerization interface [polypeptide binding]; other site
1104326000144	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1104326000145	MASE1; Region: MASE1; pfam05231
1104326000146	Histidine kinase; Region: HisKA_3; pfam07730
1104326000147	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326000148	ATP binding site [chemical binding]; other site
1104326000149	Mg2+ binding site [ion binding]; other site
1104326000150	G-X-G motif; other site
1104326000151	regulatory protein UhpC; Provisional; Region: PRK11663
1104326000152	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000153	putative substrate translocation pore; other site
1104326000154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000155	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1104326000156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000157	putative substrate translocation pore; other site
1104326000158	Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342
1104326000159	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326000160	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326000161	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326000162	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326000163	dimerization interface [polypeptide binding]; other site
1104326000164	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1104326000165	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_4; cd07822
1104326000166	putative hydrophobic ligand binding site [chemical binding]; other site
1104326000167	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1104326000168	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000169	putative substrate translocation pore; other site
1104326000170	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1104326000171	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
1104326000172	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1104326000173	EamA-like transporter family; Region: EamA; pfam00892
1104326000174	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1104326000175	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1104326000176	methionine cluster; other site
1104326000177	active site
1104326000178	phosphorylation site [posttranslational modification]
1104326000179	metal binding site [ion binding]; metal-binding site
1104326000180	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1104326000181	beta-galactosidase; Region: BGL; TIGR03356
1104326000182	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1104326000183	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1104326000184	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1104326000185	active site
1104326000186	P-loop; other site
1104326000187	phosphorylation site [posttranslational modification]
1104326000188	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326000189	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326000190	DNA binding site [nucleotide binding]
1104326000191	domain linker motif; other site
1104326000192	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1104326000193	ligand binding site [chemical binding]; other site
1104326000194	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1104326000195	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1104326000196	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326000197	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1104326000198	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326000199	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326000200	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
1104326000201	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326000202	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326000203	Coenzyme A binding pocket [chemical binding]; other site
1104326000204	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1104326000205	lipoprotein, YaeC family; Region: TIGR00363
1104326000206	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326000207	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326000208	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326000209	DNA binding residues [nucleotide binding]
1104326000210	dimerization interface [polypeptide binding]; other site
1104326000211	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326000212	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326000213	DNA binding residues [nucleotide binding]
1104326000214	dimerization interface [polypeptide binding]; other site
1104326000215	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1104326000216	Fimbrial protein; Region: Fimbrial; pfam00419
1104326000217	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326000218	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326000219	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326000220	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326000221	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1104326000222	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326000223	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326000224	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326000225	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326000226	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326000227	DNA binding site [nucleotide binding]
1104326000228	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1104326000229	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326000230	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1104326000231	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1104326000232	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1104326000233	putative active site [active]
1104326000234	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326000235	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326000236	Walker A/P-loop; other site
1104326000237	ATP binding site [chemical binding]; other site
1104326000238	Q-loop/lid; other site
1104326000239	ABC transporter signature motif; other site
1104326000240	Walker B; other site
1104326000241	D-loop; other site
1104326000242	H-loop/switch region; other site
1104326000243	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1104326000244	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326000245	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326000246	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1104326000247	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1104326000248	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1104326000249	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1104326000250	conserved cys residue [active]
1104326000251	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326000252	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1104326000253	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326000254	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326000255	DNA binding residues [nucleotide binding]
1104326000256	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
1104326000257	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1104326000258	structural tetrad; other site
1104326000259	3-carboxymuconate cyclase [Carbohydrate transport and metabolism]; Region: COG2706
1104326000260	SnoaL-like domain; Region: SnoaL_2; pfam12680
1104326000261	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1104326000262	active site
1104326000263	zinc binding site [ion binding]; other site
1104326000264	Predicted ATPase [General function prediction only]; Region: COG4637
1104326000265	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326000266	Walker A/P-loop; other site
1104326000267	ATP binding site [chemical binding]; other site
1104326000268	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326000269	ABC transporter signature motif; other site
1104326000270	Walker B; other site
1104326000271	D-loop; other site
1104326000272	H-loop/switch region; other site
1104326000273	Protein of unknown function (DUF523); Region: DUF523; pfam04463
1104326000274	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1104326000275	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1104326000276	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1104326000277	active site
1104326000278	homotetramer interface [polypeptide binding]; other site
1104326000279	transcriptional regulator MirA; Provisional; Region: PRK15043
1104326000280	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1104326000281	DNA binding residues [nucleotide binding]
1104326000282	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1104326000283	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1104326000284	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326000285	Fimbrial protein; Region: Fimbrial; cl01416
1104326000286	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326000287	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326000288	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326000289	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326000290	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1104326000291	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326000292	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326000293	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326000294	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326000295	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1104326000296	DNA binding residues [nucleotide binding]
1104326000297	dimerization interface [polypeptide binding]; other site
1104326000298	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1104326000299	DNA binding site [nucleotide binding]
1104326000300	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1104326000301	conserved cys residue [active]
1104326000302	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326000303	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326000304	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1104326000305	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326000306	Coenzyme A binding pocket [chemical binding]; other site
1104326000307	Virulence protein [General function prediction only]; Region: COG3943
1104326000308	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1104326000309	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1104326000310	HicB family; Region: HicB; pfam05534
1104326000311	glutaredoxin 2; Provisional; Region: PRK10387
1104326000312	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1104326000313	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1104326000314	putative active site [active]
1104326000315	putative NTP binding site [chemical binding]; other site
1104326000316	putative nucleic acid binding site [nucleotide binding]; other site
1104326000317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1104326000318	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
1104326000319	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
1104326000320	active site
1104326000321	metal binding site [ion binding]; metal-binding site
1104326000322	interdomain interaction site; other site
1104326000323	D5 N terminal like; Region: D5_N; smart00885
1104326000324	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
1104326000325	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1104326000326	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1104326000327	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1104326000328	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
1104326000329	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1104326000330	GAF domain; Region: GAF_3; pfam13492
1104326000331	GAF domain; Region: GAF_2; pfam13185
1104326000332	integrase; Provisional; Region: PRK09692
1104326000333	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1104326000334	active site
1104326000335	Int/Topo IB signature motif; other site
1104326000336	putative alpha-glucosidase; Provisional; Region: PRK10658
1104326000337	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1104326000338	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1104326000339	active site
1104326000340	homotrimer interface [polypeptide binding]; other site
1104326000341	catalytic site [active]
1104326000342	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1104326000343	AsmA family; Region: AsmA; pfam05170
1104326000344	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1104326000345	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1104326000346	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1104326000347	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1104326000348	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1104326000349	generic binding surface II; other site
1104326000350	ssDNA binding site; other site
1104326000351	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326000352	ATP binding site [chemical binding]; other site
1104326000353	putative Mg++ binding site [ion binding]; other site
1104326000354	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326000355	nucleotide binding region [chemical binding]; other site
1104326000356	ATP-binding site [chemical binding]; other site
1104326000357	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1104326000358	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1104326000359	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1104326000360	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1104326000361	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1104326000362	Zn2+ binding site [ion binding]; other site
1104326000363	Mg2+ binding site [ion binding]; other site
1104326000364	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1104326000365	synthetase active site [active]
1104326000366	NTP binding site [chemical binding]; other site
1104326000367	metal binding site [ion binding]; metal-binding site
1104326000368	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1104326000369	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1104326000370	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1104326000371	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1104326000372	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1104326000373	catalytic site [active]
1104326000374	G-X2-G-X-G-K; other site
1104326000375	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1104326000376	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1104326000377	nucleotide binding pocket [chemical binding]; other site
1104326000378	K-X-D-G motif; other site
1104326000379	catalytic site [active]
1104326000380	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1104326000381	Predicted membrane protein [Function unknown]; Region: COG2860
1104326000382	UPF0126 domain; Region: UPF0126; pfam03458
1104326000383	UPF0126 domain; Region: UPF0126; pfam03458
1104326000384	hypothetical protein; Provisional; Region: PRK11820
1104326000385	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1104326000386	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1104326000387	ribonuclease PH; Reviewed; Region: rph; PRK00173
1104326000388	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1104326000389	hexamer interface [polypeptide binding]; other site
1104326000390	active site
1104326000391	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326000392	active site
1104326000393	division inhibitor protein; Provisional; Region: slmA; PRK09480
1104326000394	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326000395	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1104326000396	trimer interface [polypeptide binding]; other site
1104326000397	active site
1104326000398	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1104326000399	Flavoprotein; Region: Flavoprotein; pfam02441
1104326000400	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1104326000401	hypothetical protein; Reviewed; Region: PRK00024
1104326000402	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1104326000403	MPN+ (JAMM) motif; other site
1104326000404	Zinc-binding site [ion binding]; other site
1104326000405	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1104326000406	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1104326000407	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1104326000408	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1104326000409	DNA binding site [nucleotide binding]
1104326000410	catalytic residue [active]
1104326000411	H2TH interface [polypeptide binding]; other site
1104326000412	putative catalytic residues [active]
1104326000413	turnover-facilitating residue; other site
1104326000414	intercalation triad [nucleotide binding]; other site
1104326000415	8OG recognition residue [nucleotide binding]; other site
1104326000416	putative reading head residues; other site
1104326000417	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1104326000418	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1104326000419	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1104326000420	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1104326000421	active site
1104326000422	(T/H)XGH motif; other site
1104326000423	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1104326000424	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1104326000425	putative metal binding site; other site
1104326000426	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1104326000427	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1104326000428	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
1104326000429	putative glycosyl transferase; Provisional; Region: PRK10073
1104326000430	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1104326000431	active site
1104326000432	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1104326000433	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1104326000434	putative ADP-binding pocket [chemical binding]; other site
1104326000435	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1104326000436	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1104326000437	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1104326000438	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1104326000439	putative active site [active]
1104326000440	Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs; Region: CE4_WalW; cd10935
1104326000441	putative active site [active]
1104326000442	putative catalytic site [active]
1104326000443	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
1104326000444	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1104326000445	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1104326000446	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
1104326000447	putative active site [active]
1104326000448	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1104326000449	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1104326000450	putative active site [active]
1104326000451	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1104326000452	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1104326000453	putative active site [active]
1104326000454	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1104326000455	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1104326000456	NADP binding site [chemical binding]; other site
1104326000457	homopentamer interface [polypeptide binding]; other site
1104326000458	substrate binding site [chemical binding]; other site
1104326000459	active site
1104326000460	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1104326000461	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1104326000462	substrate-cofactor binding pocket; other site
1104326000463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326000464	catalytic residue [active]
1104326000465	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1104326000466	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1104326000467	NAD(P) binding site [chemical binding]; other site
1104326000468	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1104326000469	Sulfatase; Region: Sulfatase; cl17466
1104326000470	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1104326000471	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1104326000472	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
1104326000473	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1104326000474	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1104326000475	putative metal binding site; other site
1104326000476	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1104326000477	NodB motif; other site
1104326000478	putative active site [active]
1104326000479	putative catalytic site [active]
1104326000480	Zn binding site [ion binding]; other site
1104326000481	AmiB activator; Provisional; Region: PRK11637
1104326000482	Peptidase family M23; Region: Peptidase_M23; pfam01551
1104326000483	phosphoglyceromutase; Provisional; Region: PRK05434
1104326000484	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1104326000485	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1104326000486	active site residue [active]
1104326000487	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1104326000488	GSH binding site [chemical binding]; other site
1104326000489	catalytic residues [active]
1104326000490	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1104326000491	SecA binding site; other site
1104326000492	Preprotein binding site; other site
1104326000493	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1104326000494	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1104326000495	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1104326000496	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1104326000497	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1104326000498	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1104326000499	trimer interface [polypeptide binding]; other site
1104326000500	active site
1104326000501	substrate binding site [chemical binding]; other site
1104326000502	CoA binding site [chemical binding]; other site
1104326000503	putative rRNA methylase; Provisional; Region: PRK10358
1104326000504	benzoate transport; Region: 2A0115; TIGR00895
1104326000505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000506	putative substrate translocation pore; other site
1104326000507	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000508	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1104326000509	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1104326000510	active site
1104326000511	substrate binding site [chemical binding]; other site
1104326000512	FMN binding site [chemical binding]; other site
1104326000513	putative catalytic residues [active]
1104326000514	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1104326000515	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326000516	DNA-binding site [nucleotide binding]; DNA binding site
1104326000517	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1104326000518	L-lactate permease; Provisional; Region: PRK10420
1104326000519	glycolate transporter; Provisional; Region: PRK09695
1104326000520	hypothetical protein; Provisional; Region: PRK11020
1104326000521	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1104326000522	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1104326000523	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1104326000524	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1104326000525	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1104326000526	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1104326000527	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1104326000528	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1104326000529	active site
1104326000530	P-loop; other site
1104326000531	phosphorylation site [posttranslational modification]
1104326000532	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1104326000533	active site
1104326000534	phosphorylation site [posttranslational modification]
1104326000535	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
1104326000536	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1104326000537	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326000538	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326000539	putative glutathione S-transferase; Provisional; Region: PRK10357
1104326000540	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1104326000541	putative C-terminal domain interface [polypeptide binding]; other site
1104326000542	putative GSH binding site (G-site) [chemical binding]; other site
1104326000543	putative dimer interface [polypeptide binding]; other site
1104326000544	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1104326000545	dimer interface [polypeptide binding]; other site
1104326000546	N-terminal domain interface [polypeptide binding]; other site
1104326000547	putative substrate binding pocket (H-site) [chemical binding]; other site
1104326000548	selenocysteine synthase; Provisional; Region: PRK04311
1104326000549	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1104326000550	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326000551	catalytic residue [active]
1104326000552	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1104326000553	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1104326000554	G1 box; other site
1104326000555	putative GEF interaction site [polypeptide binding]; other site
1104326000556	GTP/Mg2+ binding site [chemical binding]; other site
1104326000557	Switch I region; other site
1104326000558	G2 box; other site
1104326000559	G3 box; other site
1104326000560	Switch II region; other site
1104326000561	G4 box; other site
1104326000562	G5 box; other site
1104326000563	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1104326000564	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1104326000565	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1104326000566	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1104326000567	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1104326000568	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1104326000569	NAD(P) binding site [chemical binding]; other site
1104326000570	catalytic residues [active]
1104326000571	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326000572	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326000573	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326000574	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1104326000575	YcfA-like protein; Region: YcfA; pfam07927
1104326000576	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1104326000577	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1104326000578	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1104326000579	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326000580	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1104326000581	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326000582	Helix-turn-helix domain; Region: HTH_18; pfam12833
1104326000583	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326000584	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1104326000585	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1104326000586	intersubunit interface [polypeptide binding]; other site
1104326000587	active site
1104326000588	Zn2+ binding site [ion binding]; other site
1104326000589	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1104326000590	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1104326000591	AP (apurinic/apyrimidinic) site pocket; other site
1104326000592	DNA interaction; other site
1104326000593	Metal-binding active site; metal-binding site
1104326000594	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1104326000595	active site
1104326000596	dimer interface [polypeptide binding]; other site
1104326000597	magnesium binding site [ion binding]; other site
1104326000598	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1104326000599	putative N- and C-terminal domain interface [polypeptide binding]; other site
1104326000600	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1104326000601	putative active site [active]
1104326000602	MgATP binding site [chemical binding]; other site
1104326000603	catalytic site [active]
1104326000604	metal binding site [ion binding]; metal-binding site
1104326000605	putative xylulose binding site [chemical binding]; other site
1104326000606	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000607	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326000608	putative substrate translocation pore; other site
1104326000609	Domain of unknown function (DUF386); Region: DUF386; pfam04074
1104326000610	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1104326000611	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1104326000612	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1104326000613	Bacterial transcriptional regulator; Region: IclR; pfam01614
1104326000614	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1104326000615	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1104326000616	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326000617	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326000618	homodimer interface [polypeptide binding]; other site
1104326000619	catalytic residue [active]
1104326000620	alpha-amylase; Reviewed; Region: malS; PRK09505
1104326000621	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1104326000622	active site
1104326000623	catalytic site [active]
1104326000624	hypothetical protein; Provisional; Region: PRK10356
1104326000625	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1104326000626	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1104326000627	putative dimerization interface [polypeptide binding]; other site
1104326000628	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326000629	putative ligand binding site [chemical binding]; other site
1104326000630	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326000631	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326000632	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326000633	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326000634	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326000635	TM-ABC transporter signature motif; other site
1104326000636	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1104326000637	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326000638	Walker A/P-loop; other site
1104326000639	ATP binding site [chemical binding]; other site
1104326000640	Q-loop/lid; other site
1104326000641	ABC transporter signature motif; other site
1104326000642	Walker B; other site
1104326000643	D-loop; other site
1104326000644	H-loop/switch region; other site
1104326000645	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326000646	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1104326000647	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1104326000648	putative ligand binding site [chemical binding]; other site
1104326000649	xylose isomerase; Provisional; Region: PRK05474
1104326000650	xylose isomerase; Region: xylose_isom_A; TIGR02630
1104326000651	xylulokinase; Provisional; Region: PRK15027
1104326000652	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1104326000653	N- and C-terminal domain interface [polypeptide binding]; other site
1104326000654	active site
1104326000655	MgATP binding site [chemical binding]; other site
1104326000656	catalytic site [active]
1104326000657	metal binding site [ion binding]; metal-binding site
1104326000658	xylulose binding site [chemical binding]; other site
1104326000659	homodimer interface [polypeptide binding]; other site
1104326000660	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326000661	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
1104326000662	catalytic triad [active]
1104326000663	conserved cis-peptide bond; other site
1104326000664	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1104326000665	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1104326000666	conserved cys residue [active]
1104326000667	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326000668	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1104326000669	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1104326000670	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1104326000671	YsaB-like lipoprotein; Region: YsaB; pfam13983
1104326000672	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1104326000673	dimer interface [polypeptide binding]; other site
1104326000674	motif 1; other site
1104326000675	active site
1104326000676	motif 2; other site
1104326000677	motif 3; other site
1104326000678	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1104326000679	DALR anticodon binding domain; Region: DALR_1; pfam05746
1104326000680	anticodon binding site; other site
1104326000681	tRNA binding surface [nucleotide binding]; other site
1104326000682	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1104326000683	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326000684	Walker A/P-loop; other site
1104326000685	ATP binding site [chemical binding]; other site
1104326000686	Q-loop/lid; other site
1104326000687	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326000688	ABC transporter signature motif; other site
1104326000689	Walker B; other site
1104326000690	D-loop; other site
1104326000691	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326000692	Predicted transcriptional regulator [Transcription]; Region: COG2944
1104326000693	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326000694	salt bridge; other site
1104326000695	non-specific DNA binding site [nucleotide binding]; other site
1104326000696	sequence-specific DNA binding site [nucleotide binding]; other site
1104326000697	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1104326000698	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1104326000699	DNA-binding site [nucleotide binding]; DNA binding site
1104326000700	RNA-binding motif; other site
1104326000701	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1104326000702	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1104326000703	dimerization interface [polypeptide binding]; other site
1104326000704	ligand binding site [chemical binding]; other site
1104326000705	NADP binding site [chemical binding]; other site
1104326000706	catalytic site [active]
1104326000707	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000708	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326000709	putative substrate translocation pore; other site
1104326000710	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326000711	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1104326000712	substrate binding site [chemical binding]; other site
1104326000713	ATP binding site [chemical binding]; other site
1104326000714	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1104326000715	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326000716	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326000717	DNA binding site [nucleotide binding]
1104326000718	domain linker motif; other site
1104326000719	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
1104326000720	putative dimerization interface [polypeptide binding]; other site
1104326000721	putative ligand binding site [chemical binding]; other site
1104326000722	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1104326000723	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326000724	ligand binding site [chemical binding]; other site
1104326000725	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1104326000726	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1104326000727	molybdopterin cofactor binding site [chemical binding]; other site
1104326000728	substrate binding site [chemical binding]; other site
1104326000729	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1104326000730	molybdopterin cofactor binding site; other site
1104326000731	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1104326000732	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326000733	Coenzyme A binding pocket [chemical binding]; other site
1104326000734	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1104326000735	Autotransporter beta-domain; Region: Autotransporter; cl17461
1104326000736	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1104326000737	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326000738	putative substrate translocation pore; other site
1104326000739	phosphoethanolamine transferase; Provisional; Region: PRK11560
1104326000740	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1104326000741	Sulfatase; Region: Sulfatase; pfam00884
1104326000742	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326000743	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1104326000744	peptide binding site [polypeptide binding]; other site
1104326000745	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1104326000746	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326000747	dimer interface [polypeptide binding]; other site
1104326000748	conserved gate region; other site
1104326000749	putative PBP binding loops; other site
1104326000750	ABC-ATPase subunit interface; other site
1104326000751	dipeptide transporter; Provisional; Region: PRK10913
1104326000752	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1104326000753	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326000754	dimer interface [polypeptide binding]; other site
1104326000755	conserved gate region; other site
1104326000756	putative PBP binding loops; other site
1104326000757	ABC-ATPase subunit interface; other site
1104326000758	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1104326000759	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326000760	Walker A/P-loop; other site
1104326000761	ATP binding site [chemical binding]; other site
1104326000762	Q-loop/lid; other site
1104326000763	ABC transporter signature motif; other site
1104326000764	Walker B; other site
1104326000765	D-loop; other site
1104326000766	H-loop/switch region; other site
1104326000767	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1104326000768	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1104326000769	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326000770	Walker A/P-loop; other site
1104326000771	ATP binding site [chemical binding]; other site
1104326000772	Q-loop/lid; other site
1104326000773	ABC transporter signature motif; other site
1104326000774	Walker B; other site
1104326000775	D-loop; other site
1104326000776	H-loop/switch region; other site
1104326000777	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1104326000778	pantothenate kinase; Provisional; Region: PRK05439
1104326000779	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1104326000780	ATP-binding site [chemical binding]; other site
1104326000781	CoA-binding site [chemical binding]; other site
1104326000782	Mg2+-binding site [ion binding]; other site
1104326000783	elongation factor Tu; Reviewed; Region: PRK00049
1104326000784	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1104326000785	G1 box; other site
1104326000786	GEF interaction site [polypeptide binding]; other site
1104326000787	GTP/Mg2+ binding site [chemical binding]; other site
1104326000788	Switch I region; other site
1104326000789	G2 box; other site
1104326000790	G3 box; other site
1104326000791	Switch II region; other site
1104326000792	G4 box; other site
1104326000793	G5 box; other site
1104326000794	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1104326000795	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1104326000796	Antibiotic Binding Site [chemical binding]; other site
1104326000797	Uncharacterized protein conserved in archaea (DUF2193); Region: DUF2193; cl02034
1104326000798	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1104326000799	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1104326000800	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1104326000801	putative homodimer interface [polypeptide binding]; other site
1104326000802	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1104326000803	heterodimer interface [polypeptide binding]; other site
1104326000804	homodimer interface [polypeptide binding]; other site
1104326000805	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1104326000806	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1104326000807	23S rRNA interface [nucleotide binding]; other site
1104326000808	L7/L12 interface [polypeptide binding]; other site
1104326000809	putative thiostrepton binding site; other site
1104326000810	L25 interface [polypeptide binding]; other site
1104326000811	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1104326000812	mRNA/rRNA interface [nucleotide binding]; other site
1104326000813	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1104326000814	23S rRNA interface [nucleotide binding]; other site
1104326000815	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1104326000816	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1104326000817	core dimer interface [polypeptide binding]; other site
1104326000818	peripheral dimer interface [polypeptide binding]; other site
1104326000819	L10 interface [polypeptide binding]; other site
1104326000820	L11 interface [polypeptide binding]; other site
1104326000821	putative EF-Tu interaction site [polypeptide binding]; other site
1104326000822	putative EF-G interaction site [polypeptide binding]; other site
1104326000823	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1104326000824	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1104326000825	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1104326000826	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1104326000827	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1104326000828	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1104326000829	RPB3 interaction site [polypeptide binding]; other site
1104326000830	RPB1 interaction site [polypeptide binding]; other site
1104326000831	RPB11 interaction site [polypeptide binding]; other site
1104326000832	RPB10 interaction site [polypeptide binding]; other site
1104326000833	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1104326000834	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1104326000835	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1104326000836	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1104326000837	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1104326000838	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1104326000839	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1104326000840	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1104326000841	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1104326000842	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1104326000843	DNA binding site [nucleotide binding]
1104326000844	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1104326000845	methionine cluster; other site
1104326000846	PTS system, Lactose/Cellobiose specific IIA subunit; Region: PTS_IIA; pfam02255
1104326000847	active site
1104326000848	phosphorylation site [posttranslational modification]
1104326000849	metal binding site [ion binding]; metal-binding site
1104326000850	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1104326000851	active site
1104326000852	P-loop; other site
1104326000853	phosphorylation site [posttranslational modification]
1104326000854	Cache domain; Region: Cache_1; pfam02743
1104326000855	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326000856	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326000857	metal binding site [ion binding]; metal-binding site
1104326000858	active site
1104326000859	I-site; other site
1104326000860	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1104326000861	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326000862	FeS/SAM binding site; other site
1104326000863	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1104326000864	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1104326000865	ThiS interaction site; other site
1104326000866	putative active site [active]
1104326000867	tetramer interface [polypeptide binding]; other site
1104326000868	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1104326000869	thiS-thiF/thiG interaction site; other site
1104326000870	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1104326000871	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1104326000872	ATP binding site [chemical binding]; other site
1104326000873	substrate interface [chemical binding]; other site
1104326000874	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1104326000875	thiamine phosphate binding site [chemical binding]; other site
1104326000876	active site
1104326000877	pyrophosphate binding site [ion binding]; other site
1104326000878	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1104326000879	ThiC-associated domain; Region: ThiC-associated; pfam13667
1104326000880	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1104326000881	anti-RNA polymerase sigma 70 factor; Provisional; Region: PRK11718
1104326000882	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1104326000883	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1104326000884	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1104326000885	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1104326000886	putative NADH binding site [chemical binding]; other site
1104326000887	putative active site [active]
1104326000888	nudix motif; other site
1104326000889	putative metal binding site [ion binding]; other site
1104326000890	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1104326000891	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1104326000892	substrate binding site [chemical binding]; other site
1104326000893	active site
1104326000894	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1104326000895	Active_site [active]
1104326000896	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1104326000897	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1104326000898	IHF dimer interface [polypeptide binding]; other site
1104326000899	IHF - DNA interface [nucleotide binding]; other site
1104326000900	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1104326000901	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1104326000902	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1104326000903	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1104326000904	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1104326000905	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1104326000906	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1104326000907	purine monophosphate binding site [chemical binding]; other site
1104326000908	dimer interface [polypeptide binding]; other site
1104326000909	putative catalytic residues [active]
1104326000910	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1104326000911	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1104326000912	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1104326000913	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1104326000914	proposed active site lysine [active]
1104326000915	conserved cys residue [active]
1104326000916	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1104326000917	malate synthase A; Region: malate_syn_A; TIGR01344
1104326000918	active site
1104326000919	isocitrate lyase; Provisional; Region: PRK15063
1104326000920	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1104326000921	tetramer interface [polypeptide binding]; other site
1104326000922	active site
1104326000923	Mg2+/Mn2+ binding site [ion binding]; other site
1104326000924	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1104326000925	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1104326000926	transcriptional repressor IclR; Provisional; Region: PRK11569
1104326000927	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1104326000928	Bacterial transcriptional regulator; Region: IclR; pfam01614
1104326000929	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1104326000930	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1104326000931	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1104326000932	substrate binding pocket [chemical binding]; other site
1104326000933	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1104326000934	B12 binding site [chemical binding]; other site
1104326000935	cobalt ligand [ion binding]; other site
1104326000936	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1104326000937	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1104326000938	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1104326000939	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
1104326000940	CcdB protein; Region: CcdB; cl03380
1104326000941	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1104326000942	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326000943	RNA binding surface [nucleotide binding]; other site
1104326000944	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1104326000945	probable active site [active]
1104326000946	hypothetical protein; Provisional; Region: PRK10515
1104326000947	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1104326000948	Sodium Bile acid symporter family; Region: SBF; pfam01758
1104326000949	aspartate kinase III; Validated; Region: PRK09084
1104326000950	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1104326000951	nucleotide binding site [chemical binding]; other site
1104326000952	substrate binding site [chemical binding]; other site
1104326000953	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1104326000954	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1104326000955	dimer interface [polypeptide binding]; other site
1104326000956	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1104326000957	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1104326000958	active site
1104326000959	dimer interface [polypeptide binding]; other site
1104326000960	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1104326000961	dimer interface [polypeptide binding]; other site
1104326000962	active site
1104326000963	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1104326000964	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1104326000965	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1104326000966	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1104326000967	putative trimer interface [polypeptide binding]; other site
1104326000968	putative active site [active]
1104326000969	putative substrate binding site [chemical binding]; other site
1104326000970	putative CoA binding site [chemical binding]; other site
1104326000971	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1104326000972	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1104326000973	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326000974	dimer interface [polypeptide binding]; other site
1104326000975	conserved gate region; other site
1104326000976	putative PBP binding loops; other site
1104326000977	ABC-ATPase subunit interface; other site
1104326000978	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326000979	dimer interface [polypeptide binding]; other site
1104326000980	conserved gate region; other site
1104326000981	putative PBP binding loops; other site
1104326000982	ABC-ATPase subunit interface; other site
1104326000983	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1104326000984	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1104326000985	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1104326000986	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1104326000987	Walker A/P-loop; other site
1104326000988	ATP binding site [chemical binding]; other site
1104326000989	Q-loop/lid; other site
1104326000990	ABC transporter signature motif; other site
1104326000991	Walker B; other site
1104326000992	D-loop; other site
1104326000993	H-loop/switch region; other site
1104326000994	TOBE domain; Region: TOBE_2; pfam08402
1104326000995	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1104326000996	trimer interface; other site
1104326000997	sugar binding site [chemical binding]; other site
1104326000998	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1104326000999	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1104326001000	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1104326001001	UbiA prenyltransferase family; Region: UbiA; pfam01040
1104326001002	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1104326001003	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1104326001004	putative acyl-acceptor binding pocket; other site
1104326001005	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1104326001006	LexA repressor; Validated; Region: PRK00215
1104326001007	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1104326001008	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1104326001009	Catalytic site [active]
1104326001010	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1104326001011	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1104326001012	hypothetical protein; Provisional; Region: PRK10428
1104326001013	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1104326001014	metal binding site 2 [ion binding]; metal-binding site
1104326001015	putative DNA binding helix; other site
1104326001016	metal binding site 1 [ion binding]; metal-binding site
1104326001017	dimer interface [polypeptide binding]; other site
1104326001018	structural Zn2+ binding site [ion binding]; other site
1104326001019	Cupin domain; Region: Cupin_2; cl17218
1104326001020	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1104326001021	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1104326001022	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1104326001023	FMN binding site [chemical binding]; other site
1104326001024	active site
1104326001025	catalytic residues [active]
1104326001026	substrate binding site [chemical binding]; other site
1104326001027	phage shock protein G; Reviewed; Region: pspG; PRK09459
1104326001028	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1104326001029	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1104326001030	NADP binding site [chemical binding]; other site
1104326001031	dimer interface [polypeptide binding]; other site
1104326001032	replicative DNA helicase; Provisional; Region: PRK08006
1104326001033	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1104326001034	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1104326001035	Walker A motif; other site
1104326001036	ATP binding site [chemical binding]; other site
1104326001037	Walker B motif; other site
1104326001038	DNA binding loops [nucleotide binding]
1104326001039	alanine racemase; Reviewed; Region: alr; PRK00053
1104326001040	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1104326001041	active site
1104326001042	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1104326001043	substrate binding site [chemical binding]; other site
1104326001044	catalytic residues [active]
1104326001045	dimer interface [polypeptide binding]; other site
1104326001046	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1104326001047	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326001048	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326001049	homodimer interface [polypeptide binding]; other site
1104326001050	catalytic residue [active]
1104326001051	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326001052	active site
1104326001053	motif I; other site
1104326001054	motif II; other site
1104326001055	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1104326001056	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1104326001057	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1104326001058	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1104326001059	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1104326001060	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1104326001061	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1104326001062	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1104326001063	dimer interface [polypeptide binding]; other site
1104326001064	ssDNA binding site [nucleotide binding]; other site
1104326001065	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1104326001066	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1104326001067	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1104326001068	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1104326001069	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326001070	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1104326001071	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001072	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1104326001073	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1104326001074	DNA binding residues [nucleotide binding]
1104326001075	dimer interface [polypeptide binding]; other site
1104326001076	[2Fe-2S] cluster binding site [ion binding]; other site
1104326001077	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1104326001078	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1104326001079	putative C-terminal domain interface [polypeptide binding]; other site
1104326001080	putative GSH binding site (G-site) [chemical binding]; other site
1104326001081	putative dimer interface [polypeptide binding]; other site
1104326001082	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1104326001083	putative N-terminal domain interface [polypeptide binding]; other site
1104326001084	putative dimer interface [polypeptide binding]; other site
1104326001085	putative substrate binding pocket (H-site) [chemical binding]; other site
1104326001086	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1104326001087	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1104326001088	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1104326001089	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326001090	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326001091	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1104326001092	putative dimerization interface [polypeptide binding]; other site
1104326001093	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1104326001094	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1104326001095	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1104326001096	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1104326001097	Na binding site [ion binding]; other site
1104326001098	Predicted membrane protein [Function unknown]; Region: COG3162
1104326001099	acetyl-CoA synthetase; Provisional; Region: PRK00174
1104326001100	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1104326001101	active site
1104326001102	CoA binding site [chemical binding]; other site
1104326001103	acyl-activating enzyme (AAE) consensus motif; other site
1104326001104	AMP binding site [chemical binding]; other site
1104326001105	acetate binding site [chemical binding]; other site
1104326001106	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1104326001107	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1104326001108	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1104326001109	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1104326001110	binding surface
1104326001111	TPR motif; other site
1104326001112	Sel1-like repeats; Region: SEL1; smart00671
1104326001113	Hok/gef family; Region: HOK_GEF; pfam01848
1104326001114	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326001115	molybdopterin cofactor binding site; other site
1104326001116	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1104326001117	molybdopterin cofactor binding site; other site
1104326001118	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326001119	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326001120	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326001121	active site
1104326001122	phosphorylation site [posttranslational modification]
1104326001123	intermolecular recognition site; other site
1104326001124	dimerization interface [polypeptide binding]; other site
1104326001125	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326001126	DNA binding site [nucleotide binding]
1104326001127	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1104326001128	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326001129	substrate binding site [chemical binding]; other site
1104326001130	ATP binding site [chemical binding]; other site
1104326001131	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1104326001132	intersubunit interface [polypeptide binding]; other site
1104326001133	active site
1104326001134	zinc binding site [ion binding]; other site
1104326001135	Na+ binding site [ion binding]; other site
1104326001136	Protein of unknown function (DUF1498); Region: DUF1498; cl17840
1104326001137	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1104326001138	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
1104326001139	putative ligand binding site [chemical binding]; other site
1104326001140	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326001141	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326001142	TM-ABC transporter signature motif; other site
1104326001143	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1104326001144	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326001145	Walker A/P-loop; other site
1104326001146	ATP binding site [chemical binding]; other site
1104326001147	Q-loop/lid; other site
1104326001148	ABC transporter signature motif; other site
1104326001149	Walker B; other site
1104326001150	D-loop; other site
1104326001151	H-loop/switch region; other site
1104326001152	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326001153	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326001154	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326001155	dimerization interface [polypeptide binding]; other site
1104326001156	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326001157	dimer interface [polypeptide binding]; other site
1104326001158	phosphorylation site [posttranslational modification]
1104326001159	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326001160	ATP binding site [chemical binding]; other site
1104326001161	Mg2+ binding site [ion binding]; other site
1104326001162	G-X-G motif; other site
1104326001163	Response regulator receiver domain; Region: Response_reg; pfam00072
1104326001164	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326001165	active site
1104326001166	phosphorylation site [posttranslational modification]
1104326001167	intermolecular recognition site; other site
1104326001168	dimerization interface [polypeptide binding]; other site
1104326001169	putative hydrolase; Provisional; Region: PRK02113
1104326001170	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
1104326001171	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326001172	Coenzyme A binding pocket [chemical binding]; other site
1104326001173	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
1104326001174	Guanylate kinase; Region: Guanylate_kin; pfam00625
1104326001175	active site
1104326001176	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1104326001177	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1104326001178	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1104326001179	active site
1104326001180	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1104326001181	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1104326001182	Walker A/P-loop; other site
1104326001183	ATP binding site [chemical binding]; other site
1104326001184	Q-loop/lid; other site
1104326001185	ABC transporter signature motif; other site
1104326001186	Walker B; other site
1104326001187	D-loop; other site
1104326001188	H-loop/switch region; other site
1104326001189	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1104326001190	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326001191	Walker A/P-loop; other site
1104326001192	ATP binding site [chemical binding]; other site
1104326001193	Q-loop/lid; other site
1104326001194	ABC transporter signature motif; other site
1104326001195	Walker B; other site
1104326001196	D-loop; other site
1104326001197	H-loop/switch region; other site
1104326001198	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326001199	Phosphonate metabolism protein PhnJ; Region: PhnJ; pfam06007
1104326001200	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; pfam05861
1104326001201	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
1104326001202	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
1104326001203	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1104326001204	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326001205	DNA-binding site [nucleotide binding]; DNA binding site
1104326001206	UTRA domain; Region: UTRA; pfam07702
1104326001207	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1104326001208	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326001209	dimer interface [polypeptide binding]; other site
1104326001210	conserved gate region; other site
1104326001211	putative PBP binding loops; other site
1104326001212	ABC-ATPase subunit interface; other site
1104326001213	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1104326001214	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
1104326001215	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1104326001216	Walker A/P-loop; other site
1104326001217	ATP binding site [chemical binding]; other site
1104326001218	Q-loop/lid; other site
1104326001219	ABC transporter signature motif; other site
1104326001220	Walker B; other site
1104326001221	D-loop; other site
1104326001222	H-loop/switch region; other site
1104326001223	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1104326001224	dimer interface [polypeptide binding]; other site
1104326001225	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326001226	hypothetical protein; Provisional; Region: PRK10220
1104326001227	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1104326001228	PhnA protein; Region: PhnA; pfam03831
1104326001229	hypothetical protein; Provisional; Region: PRK09866
1104326001230	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1104326001231	G1 box; other site
1104326001232	GTP/Mg2+ binding site [chemical binding]; other site
1104326001233	G2 box; other site
1104326001234	Switch I region; other site
1104326001235	G3 box; other site
1104326001236	Switch II region; other site
1104326001237	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1104326001238	G2 box; other site
1104326001239	Switch I region; other site
1104326001240	G3 box; other site
1104326001241	Switch II region; other site
1104326001242	G4 box; other site
1104326001243	G5 box; other site
1104326001244	YjcZ-like protein; Region: YjcZ; pfam13990
1104326001245	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
1104326001246	proline/glycine betaine transporter; Provisional; Region: PRK10642
1104326001247	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326001248	putative substrate translocation pore; other site
1104326001249	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1104326001250	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1104326001251	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326001252	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
1104326001253	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326001254	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326001255	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326001256	potential frameshift: common BLAST hit: gi|296100741|ref|YP_003610887.1| Chaperone protein PmfD
1104326001257	Fimbrial protein; Region: Fimbrial; pfam00419
1104326001258	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326001259	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326001260	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1104326001261	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1104326001262	catalytic residues [active]
1104326001263	hinge region; other site
1104326001264	alpha helical domain; other site
1104326001265	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1104326001266	potential frameshift: common BLAST hit: gi|296100748|ref|YP_003610894.1| ABC transporter ATP-binding protein
1104326001267	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1104326001268	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326001269	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326001270	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1104326001271	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1104326001272	Walker A/P-loop; other site
1104326001273	ATP binding site [chemical binding]; other site
1104326001274	Q-loop/lid; other site
1104326001275	ABC transporter signature motif; other site
1104326001276	Walker B; other site
1104326001277	D-loop; other site
1104326001278	H-loop/switch region; other site
1104326001279	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1104326001280	FtsX-like permease family; Region: FtsX; pfam02687
1104326001281	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1104326001282	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1104326001283	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1104326001284	dimer interface [polypeptide binding]; other site
1104326001285	active site
1104326001286	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1104326001287	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1104326001288	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1104326001289	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326001290	NAD(P) binding site [chemical binding]; other site
1104326001291	active site
1104326001292	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1104326001293	Zn2+ binding site [ion binding]; other site
1104326001294	Mg2+ binding site [ion binding]; other site
1104326001295	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1104326001296	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326001297	DNA binding site [nucleotide binding]
1104326001298	FaeA-like protein; Region: FaeA; pfam04703
1104326001299	putative transcriptional regulator; Provisional; Region: PRK11640
1104326001300	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1104326001301	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1104326001302	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1104326001303	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1104326001304	DsbD alpha interface [polypeptide binding]; other site
1104326001305	catalytic residues [active]
1104326001306	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1104326001307	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1104326001308	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1104326001309	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1104326001310	Aspartase; Region: Aspartase; cd01357
1104326001311	active sites [active]
1104326001312	tetramer interface [polypeptide binding]; other site
1104326001313	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1104326001314	putative transporter; Provisional; Region: PRK11021
1104326001315	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1104326001316	oligomerisation interface [polypeptide binding]; other site
1104326001317	mobile loop; other site
1104326001318	roof hairpin; other site
1104326001319	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1104326001320	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1104326001321	ring oligomerisation interface [polypeptide binding]; other site
1104326001322	ATP/Mg binding site [chemical binding]; other site
1104326001323	stacking interactions; other site
1104326001324	hinge regions; other site
1104326001325	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1104326001326	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1104326001327	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326001328	FeS/SAM binding site; other site
1104326001329	elongation factor P; Validated; Region: PRK00529
1104326001330	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1104326001331	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1104326001332	RNA binding site [nucleotide binding]; other site
1104326001333	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1104326001334	RNA binding site [nucleotide binding]; other site
1104326001335	Predicted small secreted protein [Function unknown]; Region: COG5510
1104326001336	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1104326001337	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326001338	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326001339	DNA binding residues [nucleotide binding]
1104326001340	dimerization interface [polypeptide binding]; other site
1104326001341	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1104326001342	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1104326001343	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1104326001344	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
1104326001345	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1104326001346	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1104326001347	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326001348	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326001349	dimerization interface [polypeptide binding]; other site
1104326001350	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1104326001351	Iron-sulfur protein interface; other site
1104326001352	proximal quinone binding site [chemical binding]; other site
1104326001353	C-subunit interface; other site
1104326001354	distal quinone binding site; other site
1104326001355	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1104326001356	D-subunit interface [polypeptide binding]; other site
1104326001357	Iron-sulfur protein interface; other site
1104326001358	proximal quinone binding site [chemical binding]; other site
1104326001359	distal quinone binding site [chemical binding]; other site
1104326001360	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1104326001361	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1104326001362	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1104326001363	L-aspartate oxidase; Provisional; Region: PRK06175
1104326001364	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1104326001365	poxB regulator PoxA; Provisional; Region: PRK09350
1104326001366	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1104326001367	motif 1; other site
1104326001368	dimer interface [polypeptide binding]; other site
1104326001369	active site
1104326001370	motif 2; other site
1104326001371	motif 3; other site
1104326001372	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1104326001373	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1104326001374	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1104326001375	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1104326001376	GTPase RsgA; Reviewed; Region: PRK12288
1104326001377	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1104326001378	RNA binding site [nucleotide binding]; other site
1104326001379	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1104326001380	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1104326001381	GTP/Mg2+ binding site [chemical binding]; other site
1104326001382	G4 box; other site
1104326001383	G5 box; other site
1104326001384	G1 box; other site
1104326001385	Switch I region; other site
1104326001386	G2 box; other site
1104326001387	G3 box; other site
1104326001388	Switch II region; other site
1104326001389	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1104326001390	catalytic site [active]
1104326001391	putative active site [active]
1104326001392	putative substrate binding site [chemical binding]; other site
1104326001393	dimer interface [polypeptide binding]; other site
1104326001394	epoxyqueuosine reductase; Region: TIGR00276
1104326001395	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1104326001396	putative carbohydrate kinase; Provisional; Region: PRK10565
1104326001397	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1104326001398	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1104326001399	putative substrate binding site [chemical binding]; other site
1104326001400	putative ATP binding site [chemical binding]; other site
1104326001401	ADP-binding protein; Provisional; Region: PRK10646
1104326001402	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1104326001403	AMIN domain; Region: AMIN; pfam11741
1104326001404	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1104326001405	active site
1104326001406	metal binding site [ion binding]; metal-binding site
1104326001407	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1104326001408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326001409	ATP binding site [chemical binding]; other site
1104326001410	Mg2+ binding site [ion binding]; other site
1104326001411	G-X-G motif; other site
1104326001412	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1104326001413	ATP binding site [chemical binding]; other site
1104326001414	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1104326001415	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1104326001416	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1104326001417	bacterial Hfq-like; Region: Hfq; cd01716
1104326001418	hexamer interface [polypeptide binding]; other site
1104326001419	Sm1 motif; other site
1104326001420	RNA binding site [nucleotide binding]; other site
1104326001421	Sm2 motif; other site
1104326001422	GTPase HflX; Provisional; Region: PRK11058
1104326001423	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1104326001424	HflX GTPase family; Region: HflX; cd01878
1104326001425	G1 box; other site
1104326001426	GTP/Mg2+ binding site [chemical binding]; other site
1104326001427	Switch I region; other site
1104326001428	G2 box; other site
1104326001429	G3 box; other site
1104326001430	Switch II region; other site
1104326001431	G4 box; other site
1104326001432	G5 box; other site
1104326001433	FtsH protease regulator HflK; Provisional; Region: PRK10930
1104326001434	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1104326001435	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1104326001436	FtsH protease regulator HflC; Provisional; Region: PRK11029
1104326001437	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1104326001438	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1104326001439	potential frameshift: common BLAST hit: gi|365968677|ref|YP_004950238.1| adenylosuccinate synthetase
1104326001440	Predicted transcriptional regulator [Transcription]; Region: COG1959
1104326001441	transcriptional repressor NsrR; Provisional; Region: PRK11014
1104326001442	exoribonuclease R; Provisional; Region: PRK11642
1104326001443	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1104326001444	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1104326001445	RNB domain; Region: RNB; pfam00773
1104326001446	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1104326001447	RNA binding site [nucleotide binding]; other site
1104326001448	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1104326001449	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1104326001450	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1104326001451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326001452	metabolite-proton symporter; Region: 2A0106; TIGR00883
1104326001453	putative substrate translocation pore; other site
1104326001454	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1104326001455	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1104326001456	FAD binding site [chemical binding]; other site
1104326001457	substrate binding site [chemical binding]; other site
1104326001458	catalytic residues [active]
1104326001459	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326001460	dimerization interface [polypeptide binding]; other site
1104326001461	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1104326001462	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326001463	dimer interface [polypeptide binding]; other site
1104326001464	putative CheW interface [polypeptide binding]; other site
1104326001465	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326001466	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1104326001467	esterase; Provisional; Region: PRK10566
1104326001468	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326001469	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1104326001470	transcriptional repressor UlaR; Provisional; Region: PRK13509
1104326001471	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1104326001472	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326001473	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1104326001474	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1104326001475	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1104326001476	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1104326001477	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1104326001478	active site
1104326001479	P-loop; other site
1104326001480	phosphorylation site [posttranslational modification]
1104326001481	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1104326001482	active site
1104326001483	phosphorylation site [posttranslational modification]
1104326001484	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1104326001485	active site
1104326001486	dimer interface [polypeptide binding]; other site
1104326001487	magnesium binding site [ion binding]; other site
1104326001488	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1104326001489	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1104326001490	AP (apurinic/apyrimidinic) site pocket; other site
1104326001491	DNA interaction; other site
1104326001492	Metal-binding active site; metal-binding site
1104326001493	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1104326001494	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1104326001495	intersubunit interface [polypeptide binding]; other site
1104326001496	active site
1104326001497	Zn2+ binding site [ion binding]; other site
1104326001498	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326001499	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1104326001500	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1104326001501	dimer interface [polypeptide binding]; other site
1104326001502	ssDNA binding site [nucleotide binding]; other site
1104326001503	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1104326001504	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1104326001505	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1104326001506	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1104326001507	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1104326001508	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1104326001509	EamA-like transporter family; Region: EamA; pfam00892
1104326001510	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1104326001511	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1104326001512	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1104326001513	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1104326001514	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1104326001515	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1104326001516	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1104326001517	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1104326001518	Hemerythrin-like domain; Region: Hr-like; cd12108
1104326001519	Fe binding site [ion binding]; other site
1104326001520	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1104326001521	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326001522	dimer interface [polypeptide binding]; other site
1104326001523	ligand binding site [chemical binding]; other site
1104326001524	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326001525	dimerization interface [polypeptide binding]; other site
1104326001526	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326001527	dimer interface [polypeptide binding]; other site
1104326001528	putative CheW interface [polypeptide binding]; other site
1104326001529	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1104326001530	EamA-like transporter family; Region: EamA; pfam00892
1104326001531	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326001532	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326001533	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001534	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001535	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
1104326001536	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1104326001537	conserved cys residue [active]
1104326001538	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326001539	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001540	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001541	3-oxoacyl-acyl carrier protein synthase; Provisional; Region: PTZ00050
1104326001542	"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP)...; Region: elong_cond_enzymes; cd00828
1104326001543	active site
1104326001544	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1104326001545	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
1104326001546	acyl-activating enzyme (AAE) consensus motif; other site
1104326001547	active site
1104326001548	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
1104326001549	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
1104326001550	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
1104326001551	active site
1104326001552	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1104326001553	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
1104326001554	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1104326001555	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
1104326001556	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326001557	inhibitor-cofactor binding pocket; inhibition site
1104326001558	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326001559	catalytic residue [active]
1104326001560	Condensation domain; Region: Condensation; pfam00668
1104326001561	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
1104326001562	Arylesterase; Region: Arylesterase; pfam01731
1104326001563	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326001564	hypothetical protein; Provisional; Region: PRK05713
1104326001565	catalytic loop [active]
1104326001566	iron binding site [ion binding]; other site
1104326001567	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1104326001568	FAD binding pocket [chemical binding]; other site
1104326001569	conserved FAD binding motif [chemical binding]; other site
1104326001570	phosphate binding motif [ion binding]; other site
1104326001571	beta-alpha-beta structure motif; other site
1104326001572	NAD binding pocket [chemical binding]; other site
1104326001573	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
1104326001574	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1104326001575	putative di-iron ligands [ion binding]; other site
1104326001576	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326001577	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326001578	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
1104326001579	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1104326001580	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1104326001581	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1104326001582	NADP binding site [chemical binding]; other site
1104326001583	Predicted transcriptional regulators [Transcription]; Region: COG1733
1104326001584	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1104326001585	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1104326001586	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1104326001587	active site
1104326001588	metal binding site [ion binding]; metal-binding site
1104326001589	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1104326001590	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1104326001591	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1104326001592	active site
1104326001593	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; cl17398
1104326001594	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1104326001595	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1104326001596	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1104326001597	Domain of unknown function DUF21; Region: DUF21; pfam01595
1104326001598	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1104326001599	Transporter associated domain; Region: CorC_HlyC; smart01091
1104326001600	DNase/tRNase domain of colicin-like bacteriocin; Region: Colicin-DNase; cl15861
1104326001601	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1104326001602	active site
1104326001603	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1104326001604	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326001605	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326001606	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326001607	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326001608	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326001609	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326001610	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326001611	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326001612	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326001613	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326001614	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326001615	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326001616	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326001617	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326001618	DNA binding site [nucleotide binding]
1104326001619	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1104326001620	ligand binding site [chemical binding]; other site
1104326001621	dimerization interface [polypeptide binding]; other site
1104326001622	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1104326001623	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1104326001624	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1104326001625	Surface antigen; Region: Bac_surface_Ag; pfam01103
1104326001626	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1104326001627	Family of unknown function (DUF490); Region: DUF490; pfam04357
1104326001628	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1104326001629	putative active site pocket [active]
1104326001630	dimerization interface [polypeptide binding]; other site
1104326001631	putative catalytic residue [active]
1104326001632	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1104326001633	dimer interface [polypeptide binding]; other site
1104326001634	substrate binding site [chemical binding]; other site
1104326001635	metal binding sites [ion binding]; metal-binding site
1104326001636	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1104326001637	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1104326001638	putative ligand binding site [chemical binding]; other site
1104326001639	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1104326001640	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326001641	Walker A/P-loop; other site
1104326001642	ATP binding site [chemical binding]; other site
1104326001643	Q-loop/lid; other site
1104326001644	ABC transporter signature motif; other site
1104326001645	Walker B; other site
1104326001646	D-loop; other site
1104326001647	H-loop/switch region; other site
1104326001648	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326001649	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326001650	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326001651	TM-ABC transporter signature motif; other site
1104326001652	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326001653	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326001654	TM-ABC transporter signature motif; other site
1104326001655	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1104326001656	dimer interface [polypeptide binding]; other site
1104326001657	ligand binding site [chemical binding]; other site
1104326001658	HAMP domain; Region: HAMP; pfam00672
1104326001659	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1104326001660	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326001661	dimer interface [polypeptide binding]; other site
1104326001662	putative CheW interface [polypeptide binding]; other site
1104326001663	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326001664	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326001665	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1104326001666	AMP binding site [chemical binding]; other site
1104326001667	metal binding site [ion binding]; metal-binding site
1104326001668	active site
1104326001669	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1104326001670	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1104326001671	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1104326001672	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1104326001673	hypothetical protein; Provisional; Region: PRK05255
1104326001674	peptidase PmbA; Provisional; Region: PRK11040
1104326001675	cytochrome b562; Provisional; Region: PRK15058
1104326001676	Hok/gef family; Region: HOK_GEF; cl11494
1104326001677	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1104326001678	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; pfam14272
1104326001679	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1104326001680	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1104326001681	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1104326001682	dihydroorotase; Provisional; Region: PRK09237
1104326001683	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1104326001684	active site
1104326001685	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1104326001686	Protein of unknown function (DUF1341); Region: DUF1341; pfam07071
1104326001687	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1104326001688	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1104326001689	HTH domain; Region: HTH_11; pfam08279
1104326001690	Mga helix-turn-helix domain; Region: Mga; pfam05043
1104326001691	PRD domain; Region: PRD; pfam00874
1104326001692	PRD domain; Region: PRD; pfam00874
1104326001693	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1104326001694	active site
1104326001695	P-loop; other site
1104326001696	phosphorylation site [posttranslational modification]
1104326001697	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1104326001698	active site
1104326001699	phosphorylation site [posttranslational modification]
1104326001700	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1104326001701	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326001702	FeS/SAM binding site; other site
1104326001703	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1104326001704	ATP cone domain; Region: ATP-cone; pfam03477
1104326001705	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1104326001706	effector binding site; other site
1104326001707	active site
1104326001708	Zn binding site [ion binding]; other site
1104326001709	glycine loop; other site
1104326001710	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1104326001711	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1104326001712	Ca binding site [ion binding]; other site
1104326001713	active site
1104326001714	catalytic site [active]
1104326001715	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1104326001716	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1104326001717	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326001718	active site turn [active]
1104326001719	phosphorylation site [posttranslational modification]
1104326001720	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326001721	trehalose repressor; Provisional; Region: treR; PRK09492
1104326001722	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326001723	DNA binding site [nucleotide binding]
1104326001724	domain linker motif; other site
1104326001725	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1104326001726	dimerization interface [polypeptide binding]; other site
1104326001727	ligand binding site [chemical binding]; other site
1104326001728	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1104326001729	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1104326001730	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1104326001731	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1104326001732	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1104326001733	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1104326001734	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
1104326001735	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1104326001736	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
1104326001737	active site
1104326001738	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
1104326001739	N-acetylglucosamine-binding protein A; Reviewed; Region: PRK13211
1104326001740	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1104326001741	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1104326001742	homotrimer interaction site [polypeptide binding]; other site
1104326001743	putative active site [active]
1104326001744	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1104326001745	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1104326001746	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1104326001747	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1104326001748	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1104326001749	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1104326001750	Arginine repressor [Transcription]; Region: ArgR; COG1438
1104326001751	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1104326001752	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1104326001753	Predicted membrane protein [Function unknown]; Region: COG1288
1104326001754	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1104326001755	ornithine carbamoyltransferase; Validated; Region: PRK02102
1104326001756	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1104326001757	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1104326001758	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1104326001759	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1104326001760	putative substrate binding site [chemical binding]; other site
1104326001761	nucleotide binding site [chemical binding]; other site
1104326001762	nucleotide binding site [chemical binding]; other site
1104326001763	homodimer interface [polypeptide binding]; other site
1104326001764	arginine deiminase; Provisional; Region: PRK01388
1104326001765	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1104326001766	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1104326001767	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1104326001768	inhibitor site; inhibition site
1104326001769	active site
1104326001770	dimer interface [polypeptide binding]; other site
1104326001771	catalytic residue [active]
1104326001772	putative dehydratase; Provisional; Region: PRK08211
1104326001773	Dehydratase family; Region: ILVD_EDD; cl00340
1104326001774	putative symporter YagG; Provisional; Region: PRK09669
1104326001775	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326001776	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
1104326001777	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
1104326001778	inhibitor binding site; inhibition site
1104326001779	active site
1104326001780	Protein of unknown function (DUF1349); Region: DUF1349; cl01397
1104326001781	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1104326001782	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1104326001783	Bacterial transcriptional regulator; Region: IclR; pfam01614
1104326001784	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1104326001785	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1104326001786	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1104326001787	RNase E inhibitor protein; Provisional; Region: PRK11191
1104326001788	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1104326001789	active site
1104326001790	dinuclear metal binding site [ion binding]; other site
1104326001791	dimerization interface [polypeptide binding]; other site
1104326001792	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1104326001793	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1104326001794	cofactor binding site; other site
1104326001795	DNA binding site [nucleotide binding]
1104326001796	substrate interaction site [chemical binding]; other site
1104326001797	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1104326001798	phosphodiesterase; Provisional; Region: PRK12704
1104326001799	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1104326001800	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1104326001801	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326001802	S-adenosylmethionine binding site [chemical binding]; other site
1104326001803	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1104326001804	active site
1104326001805	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
1104326001806	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1104326001807	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1104326001808	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1104326001809	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1104326001810	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1104326001811	Protein of unknown function (DUF796); Region: DUF796; cl01226
1104326001812	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1104326001813	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1104326001814	active site
1104326001815	HIGH motif; other site
1104326001816	dimer interface [polypeptide binding]; other site
1104326001817	KMSKS motif; other site
1104326001818	fosfomycin resistance protein FosB; Provisional; Region: PRK04101
1104326001819	FosA, a Fosfomycin resistance protein, catalyzes the addition of glutathione to the antibiotic fosfomycin, making it inactive; Region: FosA; cd07244
1104326001820	dimer interface [polypeptide binding]; other site
1104326001821	Mn binding site [ion binding]; other site
1104326001822	K binding site [ion binding]; other site
1104326001823	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326001824	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326001825	DNA binding site [nucleotide binding]
1104326001826	domain linker motif; other site
1104326001827	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1104326001828	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
1104326001829	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1104326001830	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326001831	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1104326001832	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326001833	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1104326001834	Transmembrane secretion effector; Region: MFS_3; pfam05977
1104326001835	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326001836	putative substrate translocation pore; other site
1104326001837	DoxX; Region: DoxX; pfam07681
1104326001838	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1104326001839	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1104326001840	active site
1104326001841	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1104326001842	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326001843	catalytic triad [active]
1104326001844	dimer interface [polypeptide binding]; other site
1104326001845	conserved cis-peptide bond; other site
1104326001846	Protein of unknown function (DUF1427); Region: DUF1427; cl01771
1104326001847	Protein of unknown function (DUF1427); Region: DUF1427; pfam07235
1104326001848	Response regulator receiver domain; Region: Response_reg; pfam00072
1104326001849	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326001850	active site
1104326001851	phosphorylation site [posttranslational modification]
1104326001852	intermolecular recognition site; other site
1104326001853	dimerization interface [polypeptide binding]; other site
1104326001854	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1104326001855	substrate binding site [chemical binding]; other site
1104326001856	activation loop (A-loop); other site
1104326001857	Predicted ATPase [General function prediction only]; Region: COG3899
1104326001858	AAA ATPase domain; Region: AAA_16; pfam13191
1104326001859	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1104326001860	GAF domain; Region: GAF_2; pfam13185
1104326001861	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326001862	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326001863	putative active site [active]
1104326001864	heme pocket [chemical binding]; other site
1104326001865	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326001866	ATP binding site [chemical binding]; other site
1104326001867	Mg2+ binding site [ion binding]; other site
1104326001868	G-X-G motif; other site
1104326001869	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1104326001870	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326001871	active site
1104326001872	phosphorylation site [posttranslational modification]
1104326001873	intermolecular recognition site; other site
1104326001874	dimerization interface [polypeptide binding]; other site
1104326001875	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326001876	DNA binding residues [nucleotide binding]
1104326001877	dimerization interface [polypeptide binding]; other site
1104326001878	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1104326001879	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326001880	active site
1104326001881	metal binding site [ion binding]; metal-binding site
1104326001882	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1104326001883	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1104326001884	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326001885	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
1104326001886	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1104326001887	oligomer interface [polypeptide binding]; other site
1104326001888	active site residues [active]
1104326001889	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1104326001890	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1104326001891	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326001892	DNA-binding site [nucleotide binding]; DNA binding site
1104326001893	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326001894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326001895	homodimer interface [polypeptide binding]; other site
1104326001896	catalytic residue [active]
1104326001897	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1104326001898	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1104326001899	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326001900	DNA-binding site [nucleotide binding]; DNA binding site
1104326001901	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326001902	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326001903	homodimer interface [polypeptide binding]; other site
1104326001904	catalytic residue [active]
1104326001905	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1104326001906	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1104326001907	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326001908	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326001909	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1104326001910	putative effector binding pocket; other site
1104326001911	putative dimerization interface [polypeptide binding]; other site
1104326001912	Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138
1104326001913	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1104326001914	NAD binding site [chemical binding]; other site
1104326001915	catalytic residues [active]
1104326001916	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1104326001917	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326001918	dimerization interface [polypeptide binding]; other site
1104326001919	putative DNA binding site [nucleotide binding]; other site
1104326001920	putative Zn2+ binding site [ion binding]; other site
1104326001921	transcriptional regulator SlyA; Provisional; Region: PRK03573
1104326001922	MarR family; Region: MarR_2; cl17246
1104326001923	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1104326001924	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326001925	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326001926	Protein of unknown function (DUF2955); Region: DUF2955; pfam11168
1104326001927	Protein of unknown function (DUF445); Region: DUF445; pfam04286
1104326001928	Protein of unknown function (DUF796); Region: DUF796; cl01226
1104326001929	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1104326001930	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326001931	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326001932	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001933	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1104326001934	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1104326001935	NAD(P) binding site [chemical binding]; other site
1104326001936	catalytic residues [active]
1104326001937	YfaZ precursor; Region: YfaZ; pfam07437
1104326001938	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
1104326001939	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1104326001940	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1104326001941	P-loop, Walker A motif; other site
1104326001942	Base recognition motif; other site
1104326001943	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1104326001944	Uncharacterized small protein [Function unknown]; Region: COG2879
1104326001945	carbon starvation protein A; Provisional; Region: PRK15015
1104326001946	Carbon starvation protein CstA; Region: CstA; pfam02554
1104326001947	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1104326001948	Predicted transcriptional regulator [Transcription]; Region: COG2378
1104326001949	HTH domain; Region: HTH_11; pfam08279
1104326001950	WYL domain; Region: WYL; pfam13280
1104326001951	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1104326001952	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1104326001953	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1104326001954	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1104326001955	Cupin domain; Region: Cupin_2; pfam07883
1104326001956	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326001957	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1104326001958	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326001959	putative substrate translocation pore; other site
1104326001960	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1104326001961	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1104326001962	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1104326001963	putative substrate binding pocket [chemical binding]; other site
1104326001964	trimer interface [polypeptide binding]; other site
1104326001965	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1104326001966	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1104326001967	putative active site [active]
1104326001968	putative metal binding site [ion binding]; other site
1104326001969	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1104326001970	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1104326001971	NAD binding site [chemical binding]; other site
1104326001972	catalytic residues [active]
1104326001973	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1104326001974	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1104326001975	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1104326001976	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1104326001977	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326001978	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1104326001979	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326001980	dimer interface [polypeptide binding]; other site
1104326001981	ligand binding site [chemical binding]; other site
1104326001982	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326001983	dimerization interface [polypeptide binding]; other site
1104326001984	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326001985	dimer interface [polypeptide binding]; other site
1104326001986	putative CheW interface [polypeptide binding]; other site
1104326001987	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326001988	Coenzyme A binding pocket [chemical binding]; other site
1104326001989	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326001990	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1104326001991	DNA binding site [nucleotide binding]
1104326001992	Spore Coat Protein U domain; Region: SCPU; pfam05229
1104326001993	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326001994	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326001995	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326001996	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1104326001997	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326001998	Spore Coat Protein U domain; Region: SCPU; pfam05229
1104326001999	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326002000	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326002001	DNA binding residues [nucleotide binding]
1104326002002	dimerization interface [polypeptide binding]; other site
1104326002003	EAL domain; Region: EAL; pfam00563
1104326002004	phosphoglycerol transferase I; Provisional; Region: PRK03776
1104326002005	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1104326002006	hypothetical protein; Provisional; Region: PRK11667
1104326002007	DNA replication protein DnaC; Validated; Region: PRK07952
1104326002008	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326002009	Walker A motif; other site
1104326002010	ATP binding site [chemical binding]; other site
1104326002011	Walker B motif; other site
1104326002012	primosomal protein DnaI; Provisional; Region: PRK02854
1104326002013	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1104326002014	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326002015	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326002016	putative Zn2+ binding site [ion binding]; other site
1104326002017	putative DNA binding site [nucleotide binding]; other site
1104326002018	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326002019	hypothetical protein; Provisional; Region: PRK09917
1104326002020	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1104326002021	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1104326002022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326002023	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326002024	DNA binding residues [nucleotide binding]
1104326002025	dimerization interface [polypeptide binding]; other site
1104326002026	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1104326002027	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326002028	DNA binding residues [nucleotide binding]
1104326002029	dimerization interface [polypeptide binding]; other site
1104326002030	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1104326002031	putative deacylase active site [active]
1104326002032	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1104326002033	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1104326002034	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1104326002035	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1104326002036	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1104326002037	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326002038	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326002039	metal binding site [ion binding]; metal-binding site
1104326002040	active site
1104326002041	I-site; other site
1104326002042	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1104326002043	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1104326002044	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1104326002045	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326002046	S-adenosylmethionine binding site [chemical binding]; other site
1104326002047	DNA polymerase III subunit psi; Validated; Region: PRK06856
1104326002048	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1104326002049	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326002050	Coenzyme A binding pocket [chemical binding]; other site
1104326002051	dUMP phosphatase; Provisional; Region: PRK09449
1104326002052	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326002053	motif II; other site
1104326002054	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1104326002055	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1104326002056	G1 box; other site
1104326002057	putative GEF interaction site [polypeptide binding]; other site
1104326002058	GTP/Mg2+ binding site [chemical binding]; other site
1104326002059	Switch I region; other site
1104326002060	G2 box; other site
1104326002061	G3 box; other site
1104326002062	Switch II region; other site
1104326002063	G4 box; other site
1104326002064	G5 box; other site
1104326002065	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1104326002066	periplasmic protein; Provisional; Region: PRK10568
1104326002067	BON domain; Region: BON; pfam04972
1104326002068	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1104326002069	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1104326002070	active site
1104326002071	nucleophile elbow; other site
1104326002072	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1104326002073	active site
1104326002074	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1104326002075	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
1104326002076	hypothetical protein; Provisional; Region: PRK10977
1104326002077	Pyruvate formate lyase; Region: PFL; pfam02901
1104326002078	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1104326002079	intersubunit interface [polypeptide binding]; other site
1104326002080	active site
1104326002081	catalytic residue [active]
1104326002082	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1104326002083	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1104326002084	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1104326002085	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1104326002086	phosphopentomutase; Provisional; Region: PRK05362
1104326002087	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1104326002088	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1104326002089	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1104326002090	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1104326002091	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1104326002092	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1104326002093	hypothetical protein; Provisional; Region: PRK11246
1104326002094	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1104326002095	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1104326002096	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326002097	motif II; other site
1104326002098	DNA repair protein RadA; Region: sms; TIGR00416
1104326002099	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1104326002100	Walker A motif/ATP binding site; other site
1104326002101	ATP binding site [chemical binding]; other site
1104326002102	Walker B motif; other site
1104326002103	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1104326002104	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326002105	non-specific DNA binding site [nucleotide binding]; other site
1104326002106	salt bridge; other site
1104326002107	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1104326002108	sequence-specific DNA binding site [nucleotide binding]; other site
1104326002109	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1104326002110	active site
1104326002111	(T/H)XGH motif; other site
1104326002112	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1104326002113	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1104326002114	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1104326002115	putative NAD(P) binding site [chemical binding]; other site
1104326002116	dimer interface [polypeptide binding]; other site
1104326002117	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326002118	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326002119	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326002120	putative effector binding pocket; other site
1104326002121	dimerization interface [polypeptide binding]; other site
1104326002122	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1104326002123	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326002124	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326002125	ABC transporter; Region: ABC_tran_2; pfam12848
1104326002126	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326002127	lytic murein transglycosylase; Provisional; Region: PRK11619
1104326002128	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326002129	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326002130	catalytic residue [active]
1104326002131	Trp operon repressor; Provisional; Region: PRK01381
1104326002132	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1104326002133	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1104326002134	catalytic core [active]
1104326002135	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1104326002136	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326002137	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1104326002138	hypothetical protein; Provisional; Region: PRK10756
1104326002139	CreA protein; Region: CreA; pfam05981
1104326002140	two-component response regulator; Provisional; Region: PRK11173
1104326002141	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326002142	active site
1104326002143	phosphorylation site [posttranslational modification]
1104326002144	intermolecular recognition site; other site
1104326002145	dimerization interface [polypeptide binding]; other site
1104326002146	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326002147	DNA binding site [nucleotide binding]
1104326002148	putative RNA methyltransferase; Provisional; Region: PRK10433
1104326002149	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
1104326002150	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1104326002151	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1104326002152	putative catalytic residues [active]
1104326002153	putative nucleotide binding site [chemical binding]; other site
1104326002154	putative aspartate binding site [chemical binding]; other site
1104326002155	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1104326002156	dimer interface [polypeptide binding]; other site
1104326002157	putative threonine allosteric regulatory site; other site
1104326002158	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1104326002159	putative threonine allosteric regulatory site; other site
1104326002160	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1104326002161	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1104326002162	homoserine kinase; Provisional; Region: PRK01212
1104326002163	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1104326002164	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1104326002165	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1104326002166	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326002167	catalytic residue [active]
1104326002168	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1104326002169	hypothetical protein; Validated; Region: PRK02101
1104326002170	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1104326002171	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1104326002172	transaldolase-like protein; Provisional; Region: PTZ00411
1104326002173	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1104326002174	active site
1104326002175	dimer interface [polypeptide binding]; other site
1104326002176	catalytic residue [active]
1104326002177	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1104326002178	MPT binding site; other site
1104326002179	trimer interface [polypeptide binding]; other site
1104326002180	metabolite-proton symporter; Region: 2A0106; TIGR00883
1104326002181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326002182	putative substrate translocation pore; other site
1104326002183	hypothetical protein; Provisional; Region: PRK10659
1104326002184	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1104326002185	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1104326002186	nucleotide binding site [chemical binding]; other site
1104326002187	chaperone protein DnaJ; Provisional; Region: PRK10767
1104326002188	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1104326002189	HSP70 interaction site [polypeptide binding]; other site
1104326002190	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1104326002191	substrate binding site [polypeptide binding]; other site
1104326002192	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1104326002193	Zn binding sites [ion binding]; other site
1104326002194	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1104326002195	dimer interface [polypeptide binding]; other site
1104326002196	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1104326002197	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1104326002198	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326002199	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1104326002200	putative dimerization interface [polypeptide binding]; other site
1104326002201	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1104326002202	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1104326002203	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1104326002204	active site
1104326002205	Riboflavin kinase; Region: Flavokinase; smart00904
1104326002206	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1104326002207	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1104326002208	HIGH motif; other site
1104326002209	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1104326002210	active site
1104326002211	KMSKS motif; other site
1104326002212	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1104326002213	tRNA binding surface [nucleotide binding]; other site
1104326002214	anticodon binding site; other site
1104326002215	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1104326002216	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1104326002217	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1104326002218	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1104326002219	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1104326002220	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1104326002221	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1104326002222	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1104326002223	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1104326002224	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1104326002225	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1104326002226	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1104326002227	catalytic site [active]
1104326002228	subunit interface [polypeptide binding]; other site
1104326002229	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1104326002230	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1104326002231	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1104326002232	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1104326002233	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1104326002234	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1104326002235	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1104326002236	IMP binding site; other site
1104326002237	dimer interface [polypeptide binding]; other site
1104326002238	interdomain contacts; other site
1104326002239	partial ornithine binding site; other site
1104326002240	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1104326002241	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1104326002242	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1104326002243	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1104326002244	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1104326002245	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1104326002246	TrkA-N domain; Region: TrkA_N; pfam02254
1104326002247	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1104326002248	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1104326002249	folate binding site [chemical binding]; other site
1104326002250	NADP+ binding site [chemical binding]; other site
1104326002251	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1104326002252	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1104326002253	active site
1104326002254	metal binding site [ion binding]; metal-binding site
1104326002255	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1104326002256	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1104326002257	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1104326002258	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1104326002259	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1104326002260	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1104326002261	SurA N-terminal domain; Region: SurA_N; pfam09312
1104326002262	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1104326002263	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1104326002264	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1104326002265	OstA-like protein; Region: OstA; pfam03968
1104326002266	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1104326002267	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1104326002268	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1104326002269	putative metal binding site [ion binding]; other site
1104326002270	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1104326002271	HSP70 interaction site [polypeptide binding]; other site
1104326002272	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1104326002273	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1104326002274	active site
1104326002275	ATP-dependent helicase HepA; Validated; Region: PRK04914
1104326002276	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326002277	ATP binding site [chemical binding]; other site
1104326002278	putative Mg++ binding site [ion binding]; other site
1104326002279	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326002280	nucleotide binding region [chemical binding]; other site
1104326002281	ATP-binding site [chemical binding]; other site
1104326002282	DNA polymerase II; Reviewed; Region: PRK05762
1104326002283	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1104326002284	active site
1104326002285	catalytic site [active]
1104326002286	substrate binding site [chemical binding]; other site
1104326002287	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1104326002288	active site
1104326002289	metal-binding site
1104326002290	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1104326002291	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1104326002292	intersubunit interface [polypeptide binding]; other site
1104326002293	active site
1104326002294	Zn2+ binding site [ion binding]; other site
1104326002295	L-arabinose isomerase; Provisional; Region: PRK02929
1104326002296	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1104326002297	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1104326002298	trimer interface [polypeptide binding]; other site
1104326002299	putative substrate binding site [chemical binding]; other site
1104326002300	putative metal binding site [ion binding]; other site
1104326002301	ribulokinase; Provisional; Region: PRK04123
1104326002302	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1104326002303	N- and C-terminal domain interface [polypeptide binding]; other site
1104326002304	active site
1104326002305	MgATP binding site [chemical binding]; other site
1104326002306	catalytic site [active]
1104326002307	metal binding site [ion binding]; metal-binding site
1104326002308	carbohydrate binding site [chemical binding]; other site
1104326002309	homodimer interface [polypeptide binding]; other site
1104326002310	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1104326002311	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326002312	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326002313	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326002314	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1104326002315	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1104326002316	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1104326002317	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1104326002318	Walker A/P-loop; other site
1104326002319	ATP binding site [chemical binding]; other site
1104326002320	Q-loop/lid; other site
1104326002321	ABC transporter signature motif; other site
1104326002322	Walker B; other site
1104326002323	D-loop; other site
1104326002324	H-loop/switch region; other site
1104326002325	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1104326002326	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326002327	dimer interface [polypeptide binding]; other site
1104326002328	conserved gate region; other site
1104326002329	putative PBP binding loops; other site
1104326002330	ABC-ATPase subunit interface; other site
1104326002331	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326002332	dimer interface [polypeptide binding]; other site
1104326002333	conserved gate region; other site
1104326002334	putative PBP binding loops; other site
1104326002335	ABC-ATPase subunit interface; other site
1104326002336	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1104326002337	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1104326002338	transcriptional regulator SgrR; Provisional; Region: PRK13626
1104326002339	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1104326002340	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1104326002341	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326002342	sugar efflux transporter; Region: 2A0120; TIGR00899
1104326002343	putative substrate translocation pore; other site
1104326002344	Hok/gef family; Region: HOK_GEF; pfam01848
1104326002345	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1104326002346	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1104326002347	substrate binding site [chemical binding]; other site
1104326002348	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1104326002349	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1104326002350	substrate binding site [chemical binding]; other site
1104326002351	ligand binding site [chemical binding]; other site
1104326002352	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1104326002353	tartrate dehydrogenase; Region: TTC; TIGR02089
1104326002354	2-isopropylmalate synthase; Validated; Region: PRK00915
1104326002355	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1104326002356	active site
1104326002357	catalytic residues [active]
1104326002358	metal binding site [ion binding]; metal-binding site
1104326002359	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1104326002360	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1104326002361	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326002362	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1104326002363	putative substrate binding pocket [chemical binding]; other site
1104326002364	putative dimerization interface [polypeptide binding]; other site
1104326002365	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1104326002366	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326002367	PYR/PP interface [polypeptide binding]; other site
1104326002368	dimer interface [polypeptide binding]; other site
1104326002369	TPP binding site [chemical binding]; other site
1104326002370	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326002371	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1104326002372	TPP-binding site [chemical binding]; other site
1104326002373	dimer interface [polypeptide binding]; other site
1104326002374	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1104326002375	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1104326002376	putative valine binding site [chemical binding]; other site
1104326002377	dimer interface [polypeptide binding]; other site
1104326002378	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1104326002379	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1104326002380	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326002381	DNA binding site [nucleotide binding]
1104326002382	domain linker motif; other site
1104326002383	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1104326002384	dimerization interface [polypeptide binding]; other site
1104326002385	ligand binding site [chemical binding]; other site
1104326002386	mraZ protein; Region: TIGR00242
1104326002387	MraZ protein; Region: MraZ; pfam02381
1104326002388	MraZ protein; Region: MraZ; pfam02381
1104326002389	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1104326002390	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1104326002391	cell division protein FtsL; Provisional; Region: PRK10772
1104326002392	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1104326002393	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1104326002394	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1104326002395	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1104326002396	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1104326002397	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1104326002398	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1104326002399	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1104326002400	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1104326002401	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1104326002402	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1104326002403	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1104326002404	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1104326002405	Mg++ binding site [ion binding]; other site
1104326002406	putative catalytic motif [active]
1104326002407	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
1104326002408	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1104326002409	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1104326002410	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1104326002411	cell division protein FtsW; Provisional; Region: PRK10774
1104326002412	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1104326002413	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1104326002414	active site
1104326002415	homodimer interface [polypeptide binding]; other site
1104326002416	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1104326002417	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1104326002418	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1104326002419	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1104326002420	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1104326002421	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1104326002422	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1104326002423	cell division protein FtsQ; Provisional; Region: PRK10775
1104326002424	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1104326002425	Cell division protein FtsQ; Region: FtsQ; pfam03799
1104326002426	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1104326002427	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1104326002428	Cell division protein FtsA; Region: FtsA; pfam14450
1104326002429	cell division protein FtsZ; Validated; Region: PRK09330
1104326002430	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1104326002431	nucleotide binding site [chemical binding]; other site
1104326002432	SulA interaction site; other site
1104326002433	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1104326002434	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1104326002435	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1104326002436	SecA regulator SecM; Provisional; Region: PRK02943
1104326002437	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1104326002438	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1104326002439	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1104326002440	nucleotide binding region [chemical binding]; other site
1104326002441	ATP-binding site [chemical binding]; other site
1104326002442	SEC-C motif; Region: SEC-C; pfam02810
1104326002443	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1104326002444	active site
1104326002445	8-oxo-dGMP binding site [chemical binding]; other site
1104326002446	nudix motif; other site
1104326002447	metal binding site [ion binding]; metal-binding site
1104326002448	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1104326002449	hypothetical protein; Provisional; Region: PRK05287
1104326002450	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1104326002451	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1104326002452	CoA-binding site [chemical binding]; other site
1104326002453	ATP-binding [chemical binding]; other site
1104326002454	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1104326002455	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1104326002456	active site
1104326002457	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1104326002458	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1104326002459	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1104326002460	hypothetical protein; Provisional; Region: PRK10436
1104326002461	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1104326002462	Walker A motif; other site
1104326002463	ATP binding site [chemical binding]; other site
1104326002464	Walker B motif; other site
1104326002465	putative major pilin subunit; Provisional; Region: PRK10574
1104326002466	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1104326002467	Pilin (bacterial filament); Region: Pilin; pfam00114
1104326002468	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1104326002469	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1104326002470	dimerization interface [polypeptide binding]; other site
1104326002471	active site
1104326002472	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1104326002473	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1104326002474	amidase catalytic site [active]
1104326002475	Zn binding residues [ion binding]; other site
1104326002476	substrate binding site [chemical binding]; other site
1104326002477	regulatory protein AmpE; Provisional; Region: PRK10987
1104326002478	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1104326002479	active site
1104326002480	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1104326002481	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326002482	putative substrate translocation pore; other site
1104326002483	aromatic amino acid transporter; Provisional; Region: PRK10238
1104326002484	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1104326002485	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326002486	DNA-binding site [nucleotide binding]; DNA binding site
1104326002487	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1104326002488	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1104326002489	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1104326002490	dimer interface [polypeptide binding]; other site
1104326002491	TPP-binding site [chemical binding]; other site
1104326002492	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1104326002493	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1104326002494	E3 interaction surface; other site
1104326002495	lipoyl attachment site [posttranslational modification]; other site
1104326002496	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1104326002497	E3 interaction surface; other site
1104326002498	lipoyl attachment site [posttranslational modification]; other site
1104326002499	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1104326002500	E3 interaction surface; other site
1104326002501	lipoyl attachment site [posttranslational modification]; other site
1104326002502	e3 binding domain; Region: E3_binding; pfam02817
1104326002503	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1104326002504	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1104326002505	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1104326002506	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326002507	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1104326002508	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1104326002509	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1104326002510	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1104326002511	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1104326002512	substrate binding site [chemical binding]; other site
1104326002513	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1104326002514	substrate binding site [chemical binding]; other site
1104326002515	ligand binding site [chemical binding]; other site
1104326002516	hypothetical protein; Provisional; Region: PRK05248
1104326002517	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1104326002518	spermidine synthase; Provisional; Region: PRK00811
1104326002519	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326002520	S-adenosylmethionine binding site [chemical binding]; other site
1104326002521	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1104326002522	multicopper oxidase; Provisional; Region: PRK10965
1104326002523	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1104326002524	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1104326002525	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1104326002526	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1104326002527	Trp docking motif [polypeptide binding]; other site
1104326002528	putative active site [active]
1104326002529	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326002530	active site
1104326002531	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1104326002532	active site clefts [active]
1104326002533	zinc binding site [ion binding]; other site
1104326002534	dimer interface [polypeptide binding]; other site
1104326002535	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1104326002536	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1104326002537	Walker A/P-loop; other site
1104326002538	ATP binding site [chemical binding]; other site
1104326002539	Q-loop/lid; other site
1104326002540	ABC transporter signature motif; other site
1104326002541	Walker B; other site
1104326002542	D-loop; other site
1104326002543	H-loop/switch region; other site
1104326002544	inner membrane transport permease; Provisional; Region: PRK15066
1104326002545	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1104326002546	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1104326002547	active pocket/dimerization site; other site
1104326002548	active site
1104326002549	phosphorylation site [posttranslational modification]
1104326002550	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1104326002551	putative active site [active]
1104326002552	putative metal binding site [ion binding]; other site
1104326002553	Fimbrial protein; Region: Fimbrial; cl01416
1104326002554	putative fimbrial protein StaF; Provisional; Region: PRK15262
1104326002555	putative fimbrial protein StaE; Provisional; Region: PRK15263
1104326002556	Fimbrial protein; Region: Fimbrial; cl01416
1104326002557	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1104326002558	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326002559	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326002560	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326002561	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326002562	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326002563	major fimbrial protein StkA; Provisional; Region: PRK15307
1104326002564	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1104326002565	tetramerization interface [polypeptide binding]; other site
1104326002566	active site
1104326002567	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1104326002568	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1104326002569	active site
1104326002570	ATP-binding site [chemical binding]; other site
1104326002571	pantoate-binding site; other site
1104326002572	HXXH motif; other site
1104326002573	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1104326002574	oligomerization interface [polypeptide binding]; other site
1104326002575	active site
1104326002576	metal binding site [ion binding]; metal-binding site
1104326002577	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1104326002578	catalytic center binding site [active]
1104326002579	ATP binding site [chemical binding]; other site
1104326002580	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1104326002581	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1104326002582	active site
1104326002583	NTP binding site [chemical binding]; other site
1104326002584	metal binding triad [ion binding]; metal-binding site
1104326002585	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1104326002586	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1104326002587	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1104326002588	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1104326002589	active site
1104326002590	nucleotide binding site [chemical binding]; other site
1104326002591	HIGH motif; other site
1104326002592	KMSKS motif; other site
1104326002593	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1104326002594	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1104326002595	2'-5' RNA ligase; Provisional; Region: PRK15124
1104326002596	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1104326002597	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1104326002598	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1104326002599	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326002600	ATP binding site [chemical binding]; other site
1104326002601	putative Mg++ binding site [ion binding]; other site
1104326002602	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326002603	nucleotide binding region [chemical binding]; other site
1104326002604	ATP-binding site [chemical binding]; other site
1104326002605	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
1104326002606	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1104326002607	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1104326002608	Transglycosylase; Region: Transgly; pfam00912
1104326002609	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1104326002610	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1104326002611	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326002612	N-terminal plug; other site
1104326002613	ligand-binding site [chemical binding]; other site
1104326002614	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1104326002615	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1104326002616	Walker A/P-loop; other site
1104326002617	ATP binding site [chemical binding]; other site
1104326002618	Q-loop/lid; other site
1104326002619	ABC transporter signature motif; other site
1104326002620	Walker B; other site
1104326002621	D-loop; other site
1104326002622	H-loop/switch region; other site
1104326002623	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1104326002624	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1104326002625	siderophore binding site; other site
1104326002626	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1104326002627	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326002628	ABC-ATPase subunit  interface; other site
1104326002629	dimer interface [polypeptide binding]; other site
1104326002630	putative PBP binding regions; other site
1104326002631	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326002632	ABC-ATPase subunit  interface; other site
1104326002633	dimer interface [polypeptide binding]; other site
1104326002634	putative PBP binding regions; other site
1104326002635	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1104326002636	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326002637	inhibitor-cofactor binding pocket; inhibition site
1104326002638	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326002639	catalytic residue [active]
1104326002640	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1104326002641	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1104326002642	Cl- selectivity filter; other site
1104326002643	Cl- binding residues [ion binding]; other site
1104326002644	pore gating glutamate residue; other site
1104326002645	dimer interface [polypeptide binding]; other site
1104326002646	H+/Cl- coupling transport residue; other site
1104326002647	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1104326002648	hypothetical protein; Provisional; Region: PRK10578
1104326002649	UPF0126 domain; Region: UPF0126; pfam03458
1104326002650	UPF0126 domain; Region: UPF0126; pfam03458
1104326002651	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1104326002652	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1104326002653	cobalamin binding residues [chemical binding]; other site
1104326002654	putative BtuC binding residues; other site
1104326002655	dimer interface [polypeptide binding]; other site
1104326002656	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1104326002657	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1104326002658	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1104326002659	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1104326002660	Zn2+ binding site [ion binding]; other site
1104326002661	Mg2+ binding site [ion binding]; other site
1104326002662	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1104326002663	serine endoprotease; Provisional; Region: PRK10942
1104326002664	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1104326002665	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1104326002666	protein binding site [polypeptide binding]; other site
1104326002667	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1104326002668	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1104326002669	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1104326002670	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1104326002671	hypothetical protein; Provisional; Region: PRK13677
1104326002672	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1104326002673	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1104326002674	trimer interface [polypeptide binding]; other site
1104326002675	active site
1104326002676	substrate binding site [chemical binding]; other site
1104326002677	CoA binding site [chemical binding]; other site
1104326002678	PII uridylyl-transferase; Provisional; Region: PRK05007
1104326002679	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1104326002680	metal binding triad; other site
1104326002681	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1104326002682	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1104326002683	Zn2+ binding site [ion binding]; other site
1104326002684	Mg2+ binding site [ion binding]; other site
1104326002685	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1104326002686	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1104326002687	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1104326002688	active site
1104326002689	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1104326002690	rRNA interaction site [nucleotide binding]; other site
1104326002691	S8 interaction site; other site
1104326002692	putative laminin-1 binding site; other site
1104326002693	elongation factor Ts; Provisional; Region: tsf; PRK09377
1104326002694	UBA/TS-N domain; Region: UBA; pfam00627
1104326002695	Elongation factor TS; Region: EF_TS; pfam00889
1104326002696	Elongation factor TS; Region: EF_TS; pfam00889
1104326002697	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1104326002698	putative nucleotide binding site [chemical binding]; other site
1104326002699	uridine monophosphate binding site [chemical binding]; other site
1104326002700	homohexameric interface [polypeptide binding]; other site
1104326002701	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1104326002702	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1104326002703	hinge region; other site
1104326002704	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1104326002705	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1104326002706	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1104326002707	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1104326002708	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1104326002709	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1104326002710	catalytic residue [active]
1104326002711	putative FPP diphosphate  binding site; other site
1104326002712	putative FPP binding hydrophobic cleft; other site
1104326002713	dimer interface [polypeptide binding]; other site
1104326002714	putative IPP diphosphate binding site; other site
1104326002715	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1104326002716	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1104326002717	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1104326002718	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1104326002719	active site
1104326002720	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1104326002721	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1104326002722	protein binding site [polypeptide binding]; other site
1104326002723	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1104326002724	putative substrate binding region [chemical binding]; other site
1104326002725	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1104326002726	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1104326002727	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1104326002728	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1104326002729	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1104326002730	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1104326002731	Surface antigen; Region: Bac_surface_Ag; pfam01103
1104326002732	periplasmic chaperone; Provisional; Region: PRK10780
1104326002733	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1104326002734	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1104326002735	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1104326002736	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1104326002737	trimer interface [polypeptide binding]; other site
1104326002738	active site
1104326002739	UDP-GlcNAc binding site [chemical binding]; other site
1104326002740	lipid binding site [chemical binding]; lipid-binding site
1104326002741	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1104326002742	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1104326002743	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1104326002744	active site
1104326002745	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1104326002746	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1104326002747	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1104326002748	RNA/DNA hybrid binding site [nucleotide binding]; other site
1104326002749	active site
1104326002750	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1104326002751	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1104326002752	putative active site [active]
1104326002753	putative PHP Thumb interface [polypeptide binding]; other site
1104326002754	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1104326002755	generic binding surface II; other site
1104326002756	generic binding surface I; other site
1104326002757	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1104326002758	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1104326002759	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1104326002760	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1104326002761	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1104326002762	homodimer interface [polypeptide binding]; other site
1104326002763	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326002764	catalytic residue [active]
1104326002765	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1104326002766	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1104326002767	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326002768	putative metal binding site [ion binding]; other site
1104326002769	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1104326002770	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1104326002771	Ligand Binding Site [chemical binding]; other site
1104326002772	TilS substrate binding domain; Region: TilS; pfam09179
1104326002773	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1104326002774	Rho-binding antiterminator; Provisional; Region: PRK11625
1104326002775	hypothetical protein; Provisional; Region: PRK04964
1104326002776	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1104326002777	hypothetical protein; Provisional; Region: PRK09256
1104326002778	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1104326002779	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1104326002780	NlpE N-terminal domain; Region: NlpE; pfam04170
1104326002781	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1104326002782	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1104326002783	dimer interface [polypeptide binding]; other site
1104326002784	motif 1; other site
1104326002785	active site
1104326002786	motif 2; other site
1104326002787	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1104326002788	putative deacylase active site [active]
1104326002789	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1104326002790	active site
1104326002791	motif 3; other site
1104326002792	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1104326002793	anticodon binding site; other site
1104326002794	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1104326002795	homodimer interaction site [polypeptide binding]; other site
1104326002796	cofactor binding site; other site
1104326002797	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1104326002798	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1104326002799	lipoprotein, YaeC family; Region: TIGR00363
1104326002800	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326002801	dimer interface [polypeptide binding]; other site
1104326002802	conserved gate region; other site
1104326002803	ABC-ATPase subunit interface; other site
1104326002804	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1104326002805	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1104326002806	Walker A/P-loop; other site
1104326002807	ATP binding site [chemical binding]; other site
1104326002808	Q-loop/lid; other site
1104326002809	ABC transporter signature motif; other site
1104326002810	Walker B; other site
1104326002811	D-loop; other site
1104326002812	H-loop/switch region; other site
1104326002813	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1104326002814	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1104326002815	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326002816	active site
1104326002817	motif I; other site
1104326002818	motif II; other site
1104326002819	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326002820	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326002821	active site
1104326002822	catalytic tetrad [active]
1104326002823	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326002824	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326002825	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1104326002826	putative effector binding pocket; other site
1104326002827	dimerization interface [polypeptide binding]; other site
1104326002828	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1104326002829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326002830	putative substrate translocation pore; other site
1104326002831	hypothetical protein; Provisional; Region: PRK05421
1104326002832	putative catalytic site [active]
1104326002833	putative metal binding site [ion binding]; other site
1104326002834	putative phosphate binding site [ion binding]; other site
1104326002835	putative catalytic site [active]
1104326002836	putative phosphate binding site [ion binding]; other site
1104326002837	putative metal binding site [ion binding]; other site
1104326002838	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1104326002839	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326002840	S-adenosylmethionine binding site [chemical binding]; other site
1104326002841	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1104326002842	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326002843	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326002844	catalytic residue [active]
1104326002845	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1104326002846	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326002847	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1104326002848	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326002849	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1104326002850	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326002851	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1104326002852	RNA/DNA hybrid binding site [nucleotide binding]; other site
1104326002853	active site
1104326002854	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1104326002855	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1104326002856	active site
1104326002857	catalytic site [active]
1104326002858	substrate binding site [chemical binding]; other site
1104326002859	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002860	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002861	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002862	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002863	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002864	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002865	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002866	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326002867	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002868	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326002869	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002870	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002871	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002872	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326002873	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002874	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002875	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002876	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002877	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002878	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326002879	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002880	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002881	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002882	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002883	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326002884	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002885	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002886	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002887	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326002888	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002889	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326002890	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1104326002891	Family description; Region: VCBS; pfam13517
1104326002892	Family description; Region: VCBS; pfam13517
1104326002893	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1104326002894	Protein of unknown function (DUF2846); Region: DUF2846; pfam11008
1104326002895	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1104326002896	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326002897	ligand binding site [chemical binding]; other site
1104326002898	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1104326002899	DNA binding residues [nucleotide binding]
1104326002900	polysaccharide export protein Wza; Provisional; Region: PRK15078
1104326002901	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1104326002902	SLBB domain; Region: SLBB; pfam10531
1104326002903	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1104326002904	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1104326002905	active site
1104326002906	tyrosine kinase; Provisional; Region: PRK11519
1104326002907	Chain length determinant protein; Region: Wzz; pfam02706
1104326002908	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1104326002909	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1104326002910	Nucleotide binding site [chemical binding]; other site
1104326002911	P loop; other site
1104326002912	DTAP/Switch II; other site
1104326002913	Switch I; other site
1104326002914	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1104326002915	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1104326002916	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1104326002917	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1104326002918	Phosphopantetheinyl transferase (holo-ACP synthase) [Lipid metabolism]; Region: AcpS; COG0736
1104326002919	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1104326002920	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326002921	NAD(P) binding site [chemical binding]; other site
1104326002922	active site
1104326002923	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1104326002924	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1104326002925	Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; Region: GcvT; COG0404
1104326002926	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1104326002927	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1104326002928	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1104326002929	dimer interface [polypeptide binding]; other site
1104326002930	active site
1104326002931	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1104326002932	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1104326002933	active site
1104326002934	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1104326002935	"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP)...; Region: elong_cond_enzymes; cd00828
1104326002936	active site
1104326002937	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1104326002938	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1104326002939	Walker A/P-loop; other site
1104326002940	ATP binding site [chemical binding]; other site
1104326002941	Q-loop/lid; other site
1104326002942	ABC transporter signature motif; other site
1104326002943	Walker B; other site
1104326002944	D-loop; other site
1104326002945	H-loop/switch region; other site
1104326002946	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1104326002947	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1104326002948	FtsX-like permease family; Region: FtsX; pfam02687
1104326002949	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1104326002950	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1104326002951	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1104326002952	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326002953	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326002954	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1104326002955	putative active site [active]
1104326002956	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1104326002957	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326002958	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
1104326002959	Walker A/P-loop; other site
1104326002960	ATP binding site [chemical binding]; other site
1104326002961	Q-loop/lid; other site
1104326002962	ABC transporter signature motif; other site
1104326002963	Walker B; other site
1104326002964	D-loop; other site
1104326002965	H-loop/switch region; other site
1104326002966	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1104326002967	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1104326002968	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326002969	DNA-binding site [nucleotide binding]; DNA binding site
1104326002970	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1104326002971	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1104326002972	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326002973	Walker A/P-loop; other site
1104326002974	ATP binding site [chemical binding]; other site
1104326002975	Q-loop/lid; other site
1104326002976	ABC transporter signature motif; other site
1104326002977	Walker B; other site
1104326002978	D-loop; other site
1104326002979	H-loop/switch region; other site
1104326002980	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1104326002981	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1104326002982	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326002983	Walker A/P-loop; other site
1104326002984	ATP binding site [chemical binding]; other site
1104326002985	Q-loop/lid; other site
1104326002986	ABC transporter signature motif; other site
1104326002987	Walker B; other site
1104326002988	D-loop; other site
1104326002989	H-loop/switch region; other site
1104326002990	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1104326002991	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326002992	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_5; cd08511
1104326002993	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1104326002994	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326002995	dimer interface [polypeptide binding]; other site
1104326002996	conserved gate region; other site
1104326002997	putative PBP binding loops; other site
1104326002998	ABC-ATPase subunit interface; other site
1104326002999	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1104326003000	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326003001	dimer interface [polypeptide binding]; other site
1104326003002	conserved gate region; other site
1104326003003	putative PBP binding loops; other site
1104326003004	ABC-ATPase subunit interface; other site
1104326003005	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1104326003006	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1104326003007	C-N hydrolase family amidase; Provisional; Region: PRK10438
1104326003008	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1104326003009	putative active site [active]
1104326003010	catalytic triad [active]
1104326003011	dimer interface [polypeptide binding]; other site
1104326003012	multimer interface [polypeptide binding]; other site
1104326003013	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1104326003014	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1104326003015	active site
1104326003016	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1104326003017	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1104326003018	dimer interface [polypeptide binding]; other site
1104326003019	active site
1104326003020	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1104326003021	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1104326003022	putative active site [active]
1104326003023	putative dimer interface [polypeptide binding]; other site
1104326003024	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1104326003025	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326003026	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
1104326003027	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
1104326003028	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
1104326003029	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
1104326003030	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
1104326003031	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
1104326003032	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
1104326003033	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
1104326003034	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326003035	catalytic loop [active]
1104326003036	iron binding site [ion binding]; other site
1104326003037	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
1104326003038	FAD binding pocket [chemical binding]; other site
1104326003039	FAD binding motif [chemical binding]; other site
1104326003040	phosphate binding motif [ion binding]; other site
1104326003041	beta-alpha-beta structure motif; other site
1104326003042	NAD binding pocket [chemical binding]; other site
1104326003043	Protein of unknown function (DUF539); Region: DUF539; cl01129
1104326003044	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1104326003045	active site
1104326003046	DNA polymerase IV; Validated; Region: PRK02406
1104326003047	DNA binding site [nucleotide binding]
1104326003048	potential frameshift: common BLAST hit: gi|296101431|ref|YP_003611577.1| aminoacyl-histidine dipeptidase
1104326003049	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326003050	active site
1104326003051	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1104326003052	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1104326003053	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326003054	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1104326003055	trimer interface [polypeptide binding]; other site
1104326003056	eyelet of channel; other site
1104326003057	gamma-glutamyl kinase; Provisional; Region: PRK05429
1104326003058	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1104326003059	nucleotide binding site [chemical binding]; other site
1104326003060	homotetrameric interface [polypeptide binding]; other site
1104326003061	putative phosphate binding site [ion binding]; other site
1104326003062	putative allosteric binding site; other site
1104326003063	PUA domain; Region: PUA; pfam01472
1104326003064	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1104326003065	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1104326003066	putative catalytic cysteine [active]
1104326003067	integrase; Provisional; Region: PRK09692
1104326003068	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1104326003069	active site
1104326003070	Int/Topo IB signature motif; other site
1104326003071	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1104326003072	Prophage antirepressor [Transcription]; Region: COG3617
1104326003073	BRO family, N-terminal domain; Region: Bro-N; smart01040
1104326003074	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1104326003075	DNA binding site [nucleotide binding]
1104326003076	active site
1104326003077	Int/Topo IB signature motif; other site
1104326003078	catalytic residues [active]
1104326003079	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1104326003080	D5 N terminal like; Region: D5_N; smart00885
1104326003081	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
1104326003082	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1104326003083	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1104326003084	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1104326003085	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326003086	S-adenosylmethionine binding site [chemical binding]; other site
1104326003087	hypothetical protein; Provisional; Region: PRK13687
1104326003088	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1104326003089	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
1104326003090	putative heme binding pocket [chemical binding]; other site
1104326003091	Major royal jelly protein; Region: MRJP; pfam03022
1104326003092	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326003093	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326003094	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326003095	putative effector binding pocket; other site
1104326003096	dimerization interface [polypeptide binding]; other site
1104326003097	GAF domain; Region: GAF; cl17456
1104326003098	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326003099	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326003100	metal binding site [ion binding]; metal-binding site
1104326003101	active site
1104326003102	I-site; other site
1104326003103	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1104326003104	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1104326003105	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1104326003106	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1104326003107	metal binding site [ion binding]; metal-binding site
1104326003108	dimer interface [polypeptide binding]; other site
1104326003109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003110	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326003111	putative substrate translocation pore; other site
1104326003112	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1104326003113	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326003114	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326003115	dimerization interface [polypeptide binding]; other site
1104326003116	S-methylmethionine transporter; Provisional; Region: PRK11387
1104326003117	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
1104326003118	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1104326003119	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
1104326003120	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326003121	substrate binding pocket [chemical binding]; other site
1104326003122	membrane-bound complex binding site; other site
1104326003123	hinge residues; other site
1104326003124	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
1104326003125	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1104326003126	Walker A/P-loop; other site
1104326003127	ATP binding site [chemical binding]; other site
1104326003128	Q-loop/lid; other site
1104326003129	ABC transporter signature motif; other site
1104326003130	Walker B; other site
1104326003131	D-loop; other site
1104326003132	H-loop/switch region; other site
1104326003133	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1104326003134	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326003135	dimer interface [polypeptide binding]; other site
1104326003136	conserved gate region; other site
1104326003137	putative PBP binding loops; other site
1104326003138	ABC-ATPase subunit interface; other site
1104326003139	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
1104326003140	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
1104326003141	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1104326003142	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1104326003143	putative acyl-acceptor binding pocket; other site
1104326003144	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1104326003145	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1104326003146	dimer interface [polypeptide binding]; other site
1104326003147	active site
1104326003148	Schiff base residues; other site
1104326003149	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1104326003150	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1104326003151	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1104326003152	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1104326003153	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1104326003154	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1104326003155	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1104326003156	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326003157	catalytic triad [active]
1104326003158	conserved cis-peptide bond; other site
1104326003159	microcin B17 transporter; Reviewed; Region: PRK11098
1104326003160	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1104326003161	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1104326003162	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1104326003163	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1104326003164	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1104326003165	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1104326003166	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1104326003167	drug efflux system protein MdtG; Provisional; Region: PRK09874
1104326003168	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003169	putative substrate translocation pore; other site
1104326003170	anti-RssB factor; Provisional; Region: PRK10244
1104326003171	alkaline phosphatase; Provisional; Region: PRK10518
1104326003172	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1104326003173	dimer interface [polypeptide binding]; other site
1104326003174	active site
1104326003175	alkaline phosphatase; Provisional; Region: PRK10518
1104326003176	hypothetical protein; Provisional; Region: PRK11505
1104326003177	psiF repeat; Region: PsiF_repeat; pfam07769
1104326003178	psiF repeat; Region: PsiF_repeat; pfam07769
1104326003179	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1104326003180	MASE2 domain; Region: MASE2; pfam05230
1104326003181	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326003182	metal binding site [ion binding]; metal-binding site
1104326003183	active site
1104326003184	I-site; other site
1104326003185	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1104326003186	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1104326003187	hypothetical protein; Validated; Region: PRK00124
1104326003188	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1104326003189	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1104326003190	ADP binding site [chemical binding]; other site
1104326003191	magnesium binding site [ion binding]; other site
1104326003192	putative shikimate binding site; other site
1104326003193	hypothetical protein; Provisional; Region: PRK10380
1104326003194	hypothetical protein; Provisional; Region: PRK10481
1104326003195	hypothetical protein; Provisional; Region: PRK10579
1104326003196	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1104326003197	fructokinase; Reviewed; Region: PRK09557
1104326003198	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1104326003199	nucleotide binding site [chemical binding]; other site
1104326003200	potential frameshift: common BLAST hit: gi|296101516|ref|YP_003611662.1| exonuclease subunit SbcC
1104326003201	exonuclease subunit SbcD; Provisional; Region: PRK10966
1104326003202	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1104326003203	active site
1104326003204	metal binding site [ion binding]; metal-binding site
1104326003205	DNA binding site [nucleotide binding]
1104326003206	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1104326003207	transcriptional regulator PhoB; Provisional; Region: PRK10161
1104326003208	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326003209	active site
1104326003210	phosphorylation site [posttranslational modification]
1104326003211	intermolecular recognition site; other site
1104326003212	dimerization interface [polypeptide binding]; other site
1104326003213	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326003214	DNA binding site [nucleotide binding]
1104326003215	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1104326003216	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1104326003217	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326003218	putative active site [active]
1104326003219	heme pocket [chemical binding]; other site
1104326003220	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326003221	dimer interface [polypeptide binding]; other site
1104326003222	phosphorylation site [posttranslational modification]
1104326003223	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326003224	ATP binding site [chemical binding]; other site
1104326003225	Mg2+ binding site [ion binding]; other site
1104326003226	G-X-G motif; other site
1104326003227	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1104326003228	putative proline-specific permease; Provisional; Region: proY; PRK10580
1104326003229	Spore germination protein; Region: Spore_permease; cl17796
1104326003230	potential frameshift: common BLAST hit: gi|296101523|ref|YP_003611669.1| maltodextrin glucosidase
1104326003231	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
1104326003232	peroxidase; Provisional; Region: PRK15000
1104326003233	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1104326003234	dimer interface [polypeptide binding]; other site
1104326003235	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1104326003236	catalytic triad [active]
1104326003237	peroxidatic and resolving cysteines [active]
1104326003238	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1104326003239	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1104326003240	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1104326003241	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1104326003242	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1104326003243	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1104326003244	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1104326003245	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1104326003246	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1104326003247	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1104326003248	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1104326003249	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1104326003250	Protein export membrane protein; Region: SecD_SecF; pfam02355
1104326003251	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1104326003252	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326003253	Predicted transcriptional regulator [Transcription]; Region: COG2378
1104326003254	HTH domain; Region: HTH_11; pfam08279
1104326003255	WYL domain; Region: WYL; pfam13280
1104326003256	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1104326003257	hypothetical protein; Provisional; Region: PRK11530
1104326003258	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1104326003259	ATP cone domain; Region: ATP-cone; pfam03477
1104326003260	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1104326003261	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1104326003262	catalytic motif [active]
1104326003263	Zn binding site [ion binding]; other site
1104326003264	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1104326003265	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1104326003266	homopentamer interface [polypeptide binding]; other site
1104326003267	active site
1104326003268	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1104326003269	putative RNA binding site [nucleotide binding]; other site
1104326003270	thiamine monophosphate kinase; Provisional; Region: PRK05731
1104326003271	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1104326003272	ATP binding site [chemical binding]; other site
1104326003273	dimerization interface [polypeptide binding]; other site
1104326003274	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326003275	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326003276	active site
1104326003277	catalytic tetrad [active]
1104326003278	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1104326003279	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1104326003280	TPP-binding site; other site
1104326003281	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1104326003282	PYR/PP interface [polypeptide binding]; other site
1104326003283	dimer interface [polypeptide binding]; other site
1104326003284	TPP binding site [chemical binding]; other site
1104326003285	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1104326003286	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1104326003287	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1104326003288	substrate binding pocket [chemical binding]; other site
1104326003289	chain length determination region; other site
1104326003290	substrate-Mg2+ binding site; other site
1104326003291	catalytic residues [active]
1104326003292	aspartate-rich region 1; other site
1104326003293	active site lid residues [active]
1104326003294	aspartate-rich region 2; other site
1104326003295	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1104326003296	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1104326003297	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1104326003298	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1104326003299	Ligand Binding Site [chemical binding]; other site
1104326003300	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1104326003301	active site residue [active]
1104326003302	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1104326003303	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1104326003304	conserved cys residue [active]
1104326003305	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1104326003306	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1104326003307	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1104326003308	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1104326003309	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1104326003310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003311	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326003312	putative substrate translocation pore; other site
1104326003313	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1104326003314	UbiA prenyltransferase family; Region: UbiA; pfam01040
1104326003315	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1104326003316	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1104326003317	Subunit I/III interface [polypeptide binding]; other site
1104326003318	Subunit III/IV interface [polypeptide binding]; other site
1104326003319	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1104326003320	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1104326003321	D-pathway; other site
1104326003322	Putative ubiquinol binding site [chemical binding]; other site
1104326003323	Low-spin heme (heme b) binding site [chemical binding]; other site
1104326003324	Putative water exit pathway; other site
1104326003325	Binuclear center (heme o3/CuB) [ion binding]; other site
1104326003326	K-pathway; other site
1104326003327	Putative proton exit pathway; other site
1104326003328	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1104326003329	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1104326003330	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1104326003331	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1104326003332	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003333	putative substrate translocation pore; other site
1104326003334	hypothetical protein; Provisional; Region: PRK11627
1104326003335	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1104326003336	transcriptional regulator BolA; Provisional; Region: PRK11628
1104326003337	trigger factor; Provisional; Region: tig; PRK01490
1104326003338	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1104326003339	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1104326003340	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1104326003341	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1104326003342	oligomer interface [polypeptide binding]; other site
1104326003343	active site residues [active]
1104326003344	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1104326003345	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1104326003346	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326003347	Walker A motif; other site
1104326003348	ATP binding site [chemical binding]; other site
1104326003349	Walker B motif; other site
1104326003350	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1104326003351	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1104326003352	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1104326003353	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1104326003354	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326003355	Walker A motif; other site
1104326003356	ATP binding site [chemical binding]; other site
1104326003357	Walker B motif; other site
1104326003358	arginine finger; other site
1104326003359	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1104326003360	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1104326003361	IHF dimer interface [polypeptide binding]; other site
1104326003362	IHF - DNA interface [nucleotide binding]; other site
1104326003363	periplasmic folding chaperone; Provisional; Region: PRK10788
1104326003364	SurA N-terminal domain; Region: SurA_N_3; cl07813
1104326003365	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1104326003366	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1104326003367	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1104326003368	active site
1104326003369	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1104326003370	Ligand Binding Site [chemical binding]; other site
1104326003371	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1104326003372	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1104326003373	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1104326003374	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1104326003375	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326003376	active site
1104326003377	motif I; other site
1104326003378	motif II; other site
1104326003379	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1104326003380	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1104326003381	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326003382	catalytic residue [active]
1104326003383	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1104326003384	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326003385	putative DNA binding site [nucleotide binding]; other site
1104326003386	putative Zn2+ binding site [ion binding]; other site
1104326003387	AsnC family; Region: AsnC_trans_reg; pfam01037
1104326003388	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1104326003389	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326003390	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326003391	Walker A/P-loop; other site
1104326003392	ATP binding site [chemical binding]; other site
1104326003393	Q-loop/lid; other site
1104326003394	ABC transporter signature motif; other site
1104326003395	Walker B; other site
1104326003396	D-loop; other site
1104326003397	H-loop/switch region; other site
1104326003398	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1104326003399	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326003400	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326003401	Walker A/P-loop; other site
1104326003402	ATP binding site [chemical binding]; other site
1104326003403	Q-loop/lid; other site
1104326003404	ABC transporter signature motif; other site
1104326003405	Walker B; other site
1104326003406	D-loop; other site
1104326003407	H-loop/switch region; other site
1104326003408	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1104326003409	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1104326003410	ammonium transporter; Provisional; Region: PRK10666
1104326003411	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1104326003412	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1104326003413	active site
1104326003414	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1104326003415	catalytic triad [active]
1104326003416	dimer interface [polypeptide binding]; other site
1104326003417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1104326003418	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1104326003419	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1104326003420	DNA binding site [nucleotide binding]
1104326003421	active site
1104326003422	putative lipid kinase; Reviewed; Region: PRK13057
1104326003423	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1104326003424	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326003425	DNA-binding site [nucleotide binding]; DNA binding site
1104326003426	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326003427	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326003428	homodimer interface [polypeptide binding]; other site
1104326003429	catalytic residue [active]
1104326003430	Predicted membrane protein [Function unknown]; Region: COG2364
1104326003431	lac repressor; Reviewed; Region: lacI; PRK09526
1104326003432	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326003433	DNA binding site [nucleotide binding]
1104326003434	domain linker motif; other site
1104326003435	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1104326003436	ligand binding site [chemical binding]; other site
1104326003437	dimerization interface (open form) [polypeptide binding]; other site
1104326003438	dimerization interface (closed form) [polypeptide binding]; other site
1104326003439	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1104326003440	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1104326003441	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1104326003442	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1104326003443	Intracellular proteinase inhibitor; Region: BsuPI; pfam12690
1104326003444	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1104326003445	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1104326003446	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1104326003447	putative metal binding site [ion binding]; other site
1104326003448	putative homodimer interface [polypeptide binding]; other site
1104326003449	putative homotetramer interface [polypeptide binding]; other site
1104326003450	putative homodimer-homodimer interface [polypeptide binding]; other site
1104326003451	putative allosteric switch controlling residues; other site
1104326003452	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1104326003453	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1104326003454	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326003455	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1104326003456	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1104326003457	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1104326003458	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1104326003459	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1104326003460	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326003461	DNA-binding site [nucleotide binding]; DNA binding site
1104326003462	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326003463	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326003464	homodimer interface [polypeptide binding]; other site
1104326003465	catalytic residue [active]
1104326003466	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1104326003467	maltose O-acetyltransferase; Provisional; Region: PRK10092
1104326003468	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1104326003469	active site
1104326003470	substrate binding site [chemical binding]; other site
1104326003471	trimer interface [polypeptide binding]; other site
1104326003472	CoA binding site [chemical binding]; other site
1104326003473	gene expression modulator; Provisional; Region: PRK10945
1104326003474	Hha toxicity attenuator; Provisional; Region: PRK10667
1104326003475	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1104326003476	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326003477	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326003478	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1104326003479	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326003480	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326003481	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1104326003482	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326003483	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1104326003484	hypothetical protein; Provisional; Region: PRK11281
1104326003485	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
1104326003486	dimer interface [polypeptide binding]; other site
1104326003487	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1104326003488	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1104326003489	Protein of unknown function (DUF2496); Region: DUF2496; pfam10689
1104326003490	primosomal replication protein N''; Provisional; Region: PRK10093
1104326003491	hypothetical protein; Provisional; Region: PRK10527
1104326003492	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326003493	active site
1104326003494	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1104326003495	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326003496	Walker A motif; other site
1104326003497	ATP binding site [chemical binding]; other site
1104326003498	Walker B motif; other site
1104326003499	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1104326003500	arginine finger; other site
1104326003501	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1104326003502	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1104326003503	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1104326003504	hypothetical protein; Validated; Region: PRK00153
1104326003505	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
1104326003506	RecR protein; Region: RecR; pfam02132
1104326003507	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1104326003508	putative active site [active]
1104326003509	putative metal-binding site [ion binding]; other site
1104326003510	tetramer interface [polypeptide binding]; other site
1104326003511	heat shock protein 90; Provisional; Region: PRK05218
1104326003512	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326003513	ATP binding site [chemical binding]; other site
1104326003514	Mg2+ binding site [ion binding]; other site
1104326003515	G-X-G motif; other site
1104326003516	adenylate kinase; Reviewed; Region: adk; PRK00279
1104326003517	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1104326003518	AMP-binding site [chemical binding]; other site
1104326003519	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1104326003520	ferrochelatase; Reviewed; Region: hemH; PRK00035
1104326003521	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1104326003522	C-terminal domain interface [polypeptide binding]; other site
1104326003523	active site
1104326003524	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1104326003525	active site
1104326003526	N-terminal domain interface [polypeptide binding]; other site
1104326003527	inosine/guanosine kinase; Provisional; Region: PRK15074
1104326003528	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326003529	putative cation:proton antiport protein; Provisional; Region: PRK10669
1104326003530	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1104326003531	TrkA-N domain; Region: TrkA_N; pfam02254
1104326003532	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003533	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326003534	putative substrate translocation pore; other site
1104326003535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003536	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1104326003537	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1104326003538	active site
1104326003539	metal binding site [ion binding]; metal-binding site
1104326003540	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1104326003541	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1104326003542	putative deacylase active site [active]
1104326003543	TraB family; Region: TraB; cl12050
1104326003544	copper exporting ATPase; Provisional; Region: copA; PRK10671
1104326003545	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1104326003546	metal-binding site [ion binding]
1104326003547	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1104326003548	metal-binding site [ion binding]
1104326003549	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1104326003550	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326003551	motif II; other site
1104326003552	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1104326003553	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1104326003554	DNA binding residues [nucleotide binding]
1104326003555	dimer interface [polypeptide binding]; other site
1104326003556	copper binding site [ion binding]; other site
1104326003557	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1104326003558	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1104326003559	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1104326003560	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1104326003561	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326003562	Walker A/P-loop; other site
1104326003563	ATP binding site [chemical binding]; other site
1104326003564	Q-loop/lid; other site
1104326003565	ABC transporter signature motif; other site
1104326003566	Walker B; other site
1104326003567	D-loop; other site
1104326003568	H-loop/switch region; other site
1104326003569	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1104326003570	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1104326003571	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1104326003572	oxidoreductase; Provisional; Region: PRK08017
1104326003573	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1104326003574	NADP binding site [chemical binding]; other site
1104326003575	active site
1104326003576	steroid binding site; other site
1104326003577	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1104326003578	active site
1104326003579	catalytic triad [active]
1104326003580	oxyanion hole [active]
1104326003581	switch loop; other site
1104326003582	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1104326003583	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1104326003584	Walker A/P-loop; other site
1104326003585	ATP binding site [chemical binding]; other site
1104326003586	Q-loop/lid; other site
1104326003587	ABC transporter signature motif; other site
1104326003588	Walker B; other site
1104326003589	D-loop; other site
1104326003590	H-loop/switch region; other site
1104326003591	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1104326003592	FtsX-like permease family; Region: FtsX; pfam02687
1104326003593	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326003594	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1104326003595	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1104326003596	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1104326003597	active site residue [active]
1104326003598	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1104326003599	ATP-grasp domain; Region: ATP-grasp; pfam02222
1104326003600	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1104326003601	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1104326003602	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1104326003603	putative active site [active]
1104326003604	putative metal binding site [ion binding]; other site
1104326003605	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1104326003606	substrate binding site [chemical binding]; other site
1104326003607	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1104326003608	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1104326003609	active site
1104326003610	HIGH motif; other site
1104326003611	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1104326003612	KMSKS motif; other site
1104326003613	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1104326003614	tRNA binding surface [nucleotide binding]; other site
1104326003615	anticodon binding site; other site
1104326003616	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1104326003617	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1104326003618	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326003619	DNA binding site [nucleotide binding]
1104326003620	domain linker motif; other site
1104326003621	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1104326003622	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1104326003623	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326003624	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326003625	active site turn [active]
1104326003626	phosphorylation site [posttranslational modification]
1104326003627	ribosome-associated protein; Provisional; Region: PRK11507
1104326003628	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1104326003629	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1104326003630	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1104326003631	homodimer interface [polypeptide binding]; other site
1104326003632	NADP binding site [chemical binding]; other site
1104326003633	substrate binding site [chemical binding]; other site
1104326003634	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1104326003635	fimbrial protein FimI; Provisional; Region: PRK15200
1104326003636	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1104326003637	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326003638	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326003639	outer membrane usher protein FimD; Provisional; Region: PRK15198
1104326003640	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326003641	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326003642	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326003643	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1104326003644	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1104326003645	transcriptional regulator FimZ; Provisional; Region: PRK09935
1104326003646	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326003647	active site
1104326003648	phosphorylation site [posttranslational modification]
1104326003649	intermolecular recognition site; other site
1104326003650	dimerization interface [polypeptide binding]; other site
1104326003651	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326003652	DNA binding residues [nucleotide binding]
1104326003653	dimerization interface [polypeptide binding]; other site
1104326003654	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326003655	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1104326003656	DNA binding residues [nucleotide binding]
1104326003657	dimerization interface [polypeptide binding]; other site
1104326003658	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1104326003659	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1104326003660	Cytochrome P450; Region: p450; cl12078
1104326003661	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1104326003662	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1104326003663	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1104326003664	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326003665	dimer interface [polypeptide binding]; other site
1104326003666	conserved gate region; other site
1104326003667	ABC-ATPase subunit interface; other site
1104326003668	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326003669	dimer interface [polypeptide binding]; other site
1104326003670	conserved gate region; other site
1104326003671	putative PBP binding loops; other site
1104326003672	ABC-ATPase subunit interface; other site
1104326003673	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1104326003674	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1104326003675	Walker A/P-loop; other site
1104326003676	ATP binding site [chemical binding]; other site
1104326003677	Q-loop/lid; other site
1104326003678	ABC transporter signature motif; other site
1104326003679	Walker B; other site
1104326003680	D-loop; other site
1104326003681	H-loop/switch region; other site
1104326003682	hypothetical protein; Provisional; Region: PRK09929
1104326003683	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1104326003684	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326003685	N-terminal plug; other site
1104326003686	ligand-binding site [chemical binding]; other site
1104326003687	Predicted phosphatase [General function prediction only]; Region: PhoX; COG3211
1104326003688	phenylalanine transporter; Provisional; Region: PRK10249
1104326003689	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1104326003690	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1104326003691	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1104326003692	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1104326003693	Metal-binding active site; metal-binding site
1104326003694	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1104326003695	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326003696	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1104326003697	NAD(P) binding site [chemical binding]; other site
1104326003698	shikimate binding site; other site
1104326003699	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326003700	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326003701	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326003702	DNA binding site [nucleotide binding]
1104326003703	domain linker motif; other site
1104326003704	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1104326003705	dimerization interface [polypeptide binding]; other site
1104326003706	ligand binding site [chemical binding]; other site
1104326003707	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1104326003708	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1104326003709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003710	putative transporter; Provisional; Region: PRK10504
1104326003711	putative substrate translocation pore; other site
1104326003712	Helix-turn-helix domain; Region: HTH_31; pfam13560
1104326003713	sequence-specific DNA binding site [nucleotide binding]; other site
1104326003714	salt bridge; other site
1104326003715	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
1104326003716	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326003717	non-specific DNA binding site [nucleotide binding]; other site
1104326003718	salt bridge; other site
1104326003719	sequence-specific DNA binding site [nucleotide binding]; other site
1104326003720	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1104326003721	dimer interface [polypeptide binding]; other site
1104326003722	FMN binding site [chemical binding]; other site
1104326003723	hypothetical protein; Provisional; Region: PRK10250
1104326003724	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326003725	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326003726	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1104326003727	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1104326003728	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1104326003729	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326003730	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1104326003731	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1104326003732	golgi membrane calcium-translocating P-type ATPase; Region: ATPase-IIA2_Ca; TIGR01522
1104326003733	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1104326003734	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1104326003735	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326003736	motif II; other site
1104326003737	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1104326003738	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1104326003739	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1104326003740	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326003741	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1104326003742	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1104326003743	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1104326003744	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1104326003745	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1104326003746	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1104326003747	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
1104326003748	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1104326003749	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326003750	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326003751	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1104326003752	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1104326003753	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1104326003754	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326003755	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326003756	Domain of unknown function (DUF1795); Region: DUF1795; pfam08786
1104326003757	PAAR motif; Region: PAAR_motif; pfam05488
1104326003758	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1104326003759	RHS Repeat; Region: RHS_repeat; pfam05593
1104326003760	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1104326003761	RHS Repeat; Region: RHS_repeat; cl11982
1104326003762	RHS Repeat; Region: RHS_repeat; pfam05593
1104326003763	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
1104326003764	RHS protein; Region: RHS; pfam03527
1104326003765	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1104326003766	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
1104326003767	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1104326003768	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1104326003769	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1104326003770	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326003771	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326003772	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1104326003773	putative effector binding pocket; other site
1104326003774	putative dimerization interface [polypeptide binding]; other site
1104326003775	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1104326003776	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326003777	NAD(P) binding site [chemical binding]; other site
1104326003778	active site
1104326003779	Agrobacterium tumefaciens protein Atu4866; Region: Atu4866; pfam11512
1104326003780	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326003781	Coenzyme A binding pocket [chemical binding]; other site
1104326003782	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326003783	Helix-turn-helix domain; Region: HTH_18; pfam12833
1104326003784	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326003785	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1104326003786	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326003787	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326003788	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1104326003789	putative dimerization interface [polypeptide binding]; other site
1104326003790	putative substrate binding pocket [chemical binding]; other site
1104326003791	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1104326003792	acetolactate synthase; Reviewed; Region: PRK08617
1104326003793	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326003794	PYR/PP interface [polypeptide binding]; other site
1104326003795	dimer interface [polypeptide binding]; other site
1104326003796	TPP binding site [chemical binding]; other site
1104326003797	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326003798	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1104326003799	TPP-binding site [chemical binding]; other site
1104326003800	dimer interface [polypeptide binding]; other site
1104326003801	acetoin reductase; Validated; Region: PRK08643
1104326003802	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
1104326003803	NAD binding site [chemical binding]; other site
1104326003804	homotetramer interface [polypeptide binding]; other site
1104326003805	homodimer interface [polypeptide binding]; other site
1104326003806	active site
1104326003807	substrate binding site [chemical binding]; other site
1104326003808	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1104326003809	DNA-binding site [nucleotide binding]; DNA binding site
1104326003810	RNA-binding motif; other site
1104326003811	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1104326003812	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326003813	Walker A/P-loop; other site
1104326003814	ATP binding site [chemical binding]; other site
1104326003815	Q-loop/lid; other site
1104326003816	ABC transporter signature motif; other site
1104326003817	Walker B; other site
1104326003818	D-loop; other site
1104326003819	H-loop/switch region; other site
1104326003820	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1104326003821	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326003822	Walker A/P-loop; other site
1104326003823	ATP binding site [chemical binding]; other site
1104326003824	Q-loop/lid; other site
1104326003825	ABC transporter signature motif; other site
1104326003826	Walker B; other site
1104326003827	D-loop; other site
1104326003828	H-loop/switch region; other site
1104326003829	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1104326003830	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1104326003831	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326003832	dimer interface [polypeptide binding]; other site
1104326003833	conserved gate region; other site
1104326003834	ABC-ATPase subunit interface; other site
1104326003835	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1104326003836	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326003837	dimer interface [polypeptide binding]; other site
1104326003838	conserved gate region; other site
1104326003839	putative PBP binding loops; other site
1104326003840	ABC-ATPase subunit interface; other site
1104326003841	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326003842	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1104326003843	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
1104326003844	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326003845	PYR/PP interface [polypeptide binding]; other site
1104326003846	dimer interface [polypeptide binding]; other site
1104326003847	TPP binding site [chemical binding]; other site
1104326003848	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326003849	Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002
1104326003850	TPP-binding site [chemical binding]; other site
1104326003851	dimer interface [polypeptide binding]; other site
1104326003852	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1104326003853	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326003854	NAD(P) binding site [chemical binding]; other site
1104326003855	active site
1104326003856	choline dehydrogenase; Validated; Region: PRK02106
1104326003857	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1104326003858	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1104326003859	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1104326003860	tetrameric interface [polypeptide binding]; other site
1104326003861	NAD binding site [chemical binding]; other site
1104326003862	catalytic residues [active]
1104326003863	transcriptional regulator BetI; Validated; Region: PRK00767
1104326003864	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326003865	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1104326003866	choline transport protein BetT; Provisional; Region: PRK09928
1104326003867	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326003868	non-specific DNA binding site [nucleotide binding]; other site
1104326003869	salt bridge; other site
1104326003870	sequence-specific DNA binding site [nucleotide binding]; other site
1104326003871	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1104326003872	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1104326003873	metal binding site [ion binding]; metal-binding site
1104326003874	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1104326003875	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1104326003876	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1104326003877	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326003878	ABC-ATPase subunit  interface; other site
1104326003879	dimer interface [polypeptide binding]; other site
1104326003880	putative PBP binding regions; other site
1104326003881	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1104326003882	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326003883	ABC-ATPase subunit  interface; other site
1104326003884	dimer interface [polypeptide binding]; other site
1104326003885	putative PBP binding regions; other site
1104326003886	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1104326003887	outer membrane receptor FepA; Provisional; Region: PRK13524
1104326003888	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326003889	N-terminal plug; other site
1104326003890	ligand-binding site [chemical binding]; other site
1104326003891	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1104326003892	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1104326003893	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1104326003894	MbtH-like protein; Region: MbtH; cl01279
1104326003895	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1104326003896	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1104326003897	acyl-activating enzyme (AAE) consensus motif; other site
1104326003898	AMP binding site [chemical binding]; other site
1104326003899	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1104326003900	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1104326003901	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1104326003902	Walker A/P-loop; other site
1104326003903	ATP binding site [chemical binding]; other site
1104326003904	Q-loop/lid; other site
1104326003905	ABC transporter signature motif; other site
1104326003906	Walker B; other site
1104326003907	D-loop; other site
1104326003908	H-loop/switch region; other site
1104326003909	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1104326003910	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326003911	ABC-ATPase subunit  interface; other site
1104326003912	dimer interface [polypeptide binding]; other site
1104326003913	putative PBP binding regions; other site
1104326003914	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1104326003915	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326003916	ABC-ATPase subunit  interface; other site
1104326003917	dimer interface [polypeptide binding]; other site
1104326003918	putative PBP binding regions; other site
1104326003919	enterobactin exporter EntS; Provisional; Region: PRK10489
1104326003920	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326003921	putative substrate translocation pore; other site
1104326003922	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1104326003923	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1104326003924	siderophore binding site; other site
1104326003925	isochorismate synthase EntC; Provisional; Region: PRK15016
1104326003926	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1104326003927	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1104326003928	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1104326003929	acyl-activating enzyme (AAE) consensus motif; other site
1104326003930	active site
1104326003931	AMP binding site [chemical binding]; other site
1104326003932	substrate binding site [chemical binding]; other site
1104326003933	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1104326003934	hydrophobic substrate binding pocket; other site
1104326003935	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326003936	active site
1104326003937	conserved cis-peptide bond; other site
1104326003938	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1104326003939	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1104326003940	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1104326003941	putative NAD(P) binding site [chemical binding]; other site
1104326003942	active site
1104326003943	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1104326003944	CoenzymeA binding site [chemical binding]; other site
1104326003945	subunit interaction site [polypeptide binding]; other site
1104326003946	PHB binding site; other site
1104326003947	carbon starvation protein A; Provisional; Region: PRK15015
1104326003948	Carbon starvation protein CstA; Region: CstA; pfam02554
1104326003949	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1104326003950	Uncharacterized small protein [Function unknown]; Region: COG2879
1104326003951	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1104326003952	classical (c) SDRs; Region: SDR_c; cd05233
1104326003953	NAD(P) binding site [chemical binding]; other site
1104326003954	active site
1104326003955	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1104326003956	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1104326003957	putative active site [active]
1104326003958	metal binding site [ion binding]; metal-binding site
1104326003959	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1104326003960	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326003961	Walker A/P-loop; other site
1104326003962	ATP binding site [chemical binding]; other site
1104326003963	Q-loop/lid; other site
1104326003964	ABC transporter signature motif; other site
1104326003965	Walker B; other site
1104326003966	D-loop; other site
1104326003967	H-loop/switch region; other site
1104326003968	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326003969	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326003970	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326003971	TM-ABC transporter signature motif; other site
1104326003972	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1104326003973	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1104326003974	putative ligand binding site [chemical binding]; other site
1104326003975	Uncharacterized conserved protein [Function unknown]; Region: COG5276
1104326003976	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1104326003977	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1104326003978	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1104326003979	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1104326003980	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1104326003981	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1104326003982	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
1104326003983	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
1104326003984	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1104326003985	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1104326003986	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1104326003987	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_3; cd08896
1104326003988	putative hydrophobic ligand binding site [chemical binding]; other site
1104326003989	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1104326003990	Cupin domain; Region: Cupin_2; cl17218
1104326003991	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
1104326003992	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326003993	motif II; other site
1104326003994	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
1104326003995	intersubunit interface [polypeptide binding]; other site
1104326003996	active site
1104326003997	Zn2+ binding site [ion binding]; other site
1104326003998	methionine aminotransferase; Validated; Region: PRK09082
1104326003999	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326004000	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326004001	homodimer interface [polypeptide binding]; other site
1104326004002	catalytic residue [active]
1104326004003	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1104326004004	ParB-like nuclease domain; Region: ParBc; pfam02195
1104326004005	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1104326004006	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1104326004007	Active Sites [active]
1104326004008	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1104326004009	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1104326004010	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326004011	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1104326004012	dimerization interface [polypeptide binding]; other site
1104326004013	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1104326004014	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1104326004015	dimer interface [polypeptide binding]; other site
1104326004016	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1104326004017	catalytic triad [active]
1104326004018	peroxidatic and resolving cysteines [active]
1104326004019	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1104326004020	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1104326004021	catalytic residue [active]
1104326004022	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1104326004023	catalytic residues [active]
1104326004024	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326004025	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326004026	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326004027	Ligand Binding Site [chemical binding]; other site
1104326004028	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1104326004029	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1104326004030	NAD binding site [chemical binding]; other site
1104326004031	catalytic Zn binding site [ion binding]; other site
1104326004032	structural Zn binding site [ion binding]; other site
1104326004033	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1104326004034	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1104326004035	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1104326004036	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1104326004037	B1 nucleotide binding pocket [chemical binding]; other site
1104326004038	B2 nucleotide binding pocket [chemical binding]; other site
1104326004039	CAS motifs; other site
1104326004040	active site
1104326004041	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1104326004042	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1104326004043	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1104326004044	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1104326004045	DNA-binding site [nucleotide binding]; DNA binding site
1104326004046	RNA-binding motif; other site
1104326004047	chromosome condensation membrane protein; Provisional; Region: PRK14196
1104326004048	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1104326004049	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1104326004050	putative active site [active]
1104326004051	catalytic triad [active]
1104326004052	putative dimer interface [polypeptide binding]; other site
1104326004053	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1104326004054	lipoyl synthase; Provisional; Region: PRK05481
1104326004055	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326004056	FeS/SAM binding site; other site
1104326004057	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1104326004058	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326004059	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1104326004060	substrate binding pocket [chemical binding]; other site
1104326004061	dimerization interface [polypeptide binding]; other site
1104326004062	lipoate-protein ligase B; Provisional; Region: PRK14342
1104326004063	hypothetical protein; Provisional; Region: PRK04998
1104326004064	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1104326004065	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1104326004066	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1104326004067	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1104326004068	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1104326004069	Sporulation related domain; Region: SPOR; pfam05036
1104326004070	cell wall shape-determining protein; Provisional; Region: PRK10794
1104326004071	penicillin-binding protein 2; Provisional; Region: PRK10795
1104326004072	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1104326004073	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1104326004074	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1104326004075	ribosome-associated protein; Provisional; Region: PRK11538
1104326004076	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1104326004077	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1104326004078	active site
1104326004079	(T/H)XGH motif; other site
1104326004080	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1104326004081	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1104326004082	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1104326004083	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1104326004084	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1104326004085	HIGH motif; other site
1104326004086	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1104326004087	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1104326004088	active site
1104326004089	KMSKS motif; other site
1104326004090	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1104326004091	tRNA binding surface [nucleotide binding]; other site
1104326004092	hypothetical protein; Provisional; Region: PRK11032
1104326004093	Predicted integral membrane metal-binding protein (DUF2296); Region: DUF2296; pfam10058
1104326004094	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1104326004095	active site
1104326004096	tetramer interface [polypeptide binding]; other site
1104326004097	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1104326004098	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326004099	Walker A/P-loop; other site
1104326004100	ATP binding site [chemical binding]; other site
1104326004101	Q-loop/lid; other site
1104326004102	ABC transporter signature motif; other site
1104326004103	Walker B; other site
1104326004104	D-loop; other site
1104326004105	H-loop/switch region; other site
1104326004106	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326004107	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004108	dimer interface [polypeptide binding]; other site
1104326004109	conserved gate region; other site
1104326004110	putative PBP binding loops; other site
1104326004111	ABC-ATPase subunit interface; other site
1104326004112	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326004113	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004114	dimer interface [polypeptide binding]; other site
1104326004115	conserved gate region; other site
1104326004116	putative PBP binding loops; other site
1104326004117	ABC-ATPase subunit interface; other site
1104326004118	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1104326004119	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326004120	substrate binding pocket [chemical binding]; other site
1104326004121	membrane-bound complex binding site; other site
1104326004122	hinge residues; other site
1104326004123	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1104326004124	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1104326004125	putative active site [active]
1104326004126	catalytic triad [active]
1104326004127	putative dimer interface [polypeptide binding]; other site
1104326004128	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1104326004129	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1104326004130	Transporter associated domain; Region: CorC_HlyC; smart01091
1104326004131	metal-binding heat shock protein; Provisional; Region: PRK00016
1104326004132	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1104326004133	PhoH-like protein; Region: PhoH; pfam02562
1104326004134	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1104326004135	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1104326004136	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326004137	FeS/SAM binding site; other site
1104326004138	TRAM domain; Region: TRAM; pfam01938
1104326004139	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1104326004140	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1104326004141	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1104326004142	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1104326004143	active site
1104326004144	dimer interface [polypeptide binding]; other site
1104326004145	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1104326004146	Ligand Binding Site [chemical binding]; other site
1104326004147	Molecular Tunnel; other site
1104326004148	UMP phosphatase; Provisional; Region: PRK10444
1104326004149	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004150	active site
1104326004151	motif I; other site
1104326004152	motif II; other site
1104326004153	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004154	MarR family; Region: MarR; pfam01047
1104326004155	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1104326004156	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1104326004157	nucleotide binding site [chemical binding]; other site
1104326004158	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1104326004159	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1104326004160	active site
1104326004161	dimer interface [polypeptide binding]; other site
1104326004162	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1104326004163	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1104326004164	active site
1104326004165	trimer interface [polypeptide binding]; other site
1104326004166	allosteric site; other site
1104326004167	active site lid [active]
1104326004168	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1104326004169	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1104326004170	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326004171	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326004172	active site turn [active]
1104326004173	phosphorylation site [posttranslational modification]
1104326004174	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1104326004175	HPr interaction site; other site
1104326004176	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1104326004177	active site
1104326004178	phosphorylation site [posttranslational modification]
1104326004179	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1104326004180	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1104326004181	active site
1104326004182	HIGH motif; other site
1104326004183	nucleotide binding site [chemical binding]; other site
1104326004184	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1104326004185	KMSKS motif; other site
1104326004186	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1104326004187	outer membrane porin, OprD family; Region: OprD; pfam03573
1104326004188	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1104326004189	YbfN-like lipoprotein; Region: YbfN; pfam13982
1104326004190	ferric uptake regulator; Provisional; Region: fur; PRK09462
1104326004191	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1104326004192	metal binding site 2 [ion binding]; metal-binding site
1104326004193	putative DNA binding helix; other site
1104326004194	metal binding site 1 [ion binding]; metal-binding site
1104326004195	dimer interface [polypeptide binding]; other site
1104326004196	structural Zn2+ binding site [ion binding]; other site
1104326004197	flavodoxin FldA; Validated; Region: PRK09267
1104326004198	LexA regulated protein; Provisional; Region: PRK11675
1104326004199	acyl-CoA esterase; Provisional; Region: PRK10673
1104326004200	PGAP1-like protein; Region: PGAP1; pfam07819
1104326004201	replication initiation regulator SeqA; Provisional; Region: PRK11187
1104326004202	phosphoglucomutase; Validated; Region: PRK07564
1104326004203	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1104326004204	active site
1104326004205	substrate binding site [chemical binding]; other site
1104326004206	metal binding site [ion binding]; metal-binding site
1104326004207	putrescine transporter; Provisional; Region: potE; PRK10655
1104326004208	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1104326004209	ornithine decarboxylase; Provisional; Region: PRK13578
1104326004210	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1104326004211	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1104326004212	homodimer interface [polypeptide binding]; other site
1104326004213	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326004214	catalytic residue [active]
1104326004215	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1104326004216	Protein of unknown function (DUF2618); Region: DUF2618; pfam10940
1104326004217	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1104326004218	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326004219	active site
1104326004220	phosphorylation site [posttranslational modification]
1104326004221	intermolecular recognition site; other site
1104326004222	dimerization interface [polypeptide binding]; other site
1104326004223	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326004224	DNA binding site [nucleotide binding]
1104326004225	sensor protein KdpD; Provisional; Region: PRK10490
1104326004226	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1104326004227	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1104326004228	Ligand Binding Site [chemical binding]; other site
1104326004229	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1104326004230	GAF domain; Region: GAF_3; pfam13492
1104326004231	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326004232	dimer interface [polypeptide binding]; other site
1104326004233	phosphorylation site [posttranslational modification]
1104326004234	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326004235	ATP binding site [chemical binding]; other site
1104326004236	Mg2+ binding site [ion binding]; other site
1104326004237	G-X-G motif; other site
1104326004238	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1104326004239	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1104326004240	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1104326004241	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1104326004242	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1104326004243	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1104326004244	DNA photolyase; Region: DNA_photolyase; pfam00875
1104326004245	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1104326004246	metal-binding protein; Provisional; Region: PRK10799
1104326004247	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1104326004248	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1104326004249	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1104326004250	LamB/YcsF family protein; Provisional; Region: PRK05406
1104326004251	endonuclease VIII; Provisional; Region: PRK10445
1104326004252	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1104326004253	DNA binding site [nucleotide binding]
1104326004254	catalytic residue [active]
1104326004255	putative catalytic residues [active]
1104326004256	H2TH interface [polypeptide binding]; other site
1104326004257	intercalation triad [nucleotide binding]; other site
1104326004258	substrate specificity determining residue; other site
1104326004259	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1104326004260	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1104326004261	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1104326004262	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1104326004263	dimer interface [polypeptide binding]; other site
1104326004264	active site
1104326004265	citrylCoA binding site [chemical binding]; other site
1104326004266	NADH binding [chemical binding]; other site
1104326004267	cationic pore residues; other site
1104326004268	oxalacetate/citrate binding site [chemical binding]; other site
1104326004269	coenzyme A binding site [chemical binding]; other site
1104326004270	catalytic triad [active]
1104326004271	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1104326004272	Iron-sulfur protein interface; other site
1104326004273	proximal quinone binding site [chemical binding]; other site
1104326004274	SdhD (CybS) interface [polypeptide binding]; other site
1104326004275	proximal heme binding site [chemical binding]; other site
1104326004276	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1104326004277	SdhC subunit interface [polypeptide binding]; other site
1104326004278	proximal heme binding site [chemical binding]; other site
1104326004279	cardiolipin binding site; other site
1104326004280	Iron-sulfur protein interface; other site
1104326004281	proximal quinone binding site [chemical binding]; other site
1104326004282	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1104326004283	L-aspartate oxidase; Provisional; Region: PRK06175
1104326004284	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1104326004285	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1104326004286	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1104326004287	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1104326004288	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1104326004289	TPP-binding site [chemical binding]; other site
1104326004290	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1104326004291	dimer interface [polypeptide binding]; other site
1104326004292	PYR/PP interface [polypeptide binding]; other site
1104326004293	TPP binding site [chemical binding]; other site
1104326004294	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1104326004295	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1104326004296	E3 interaction surface; other site
1104326004297	lipoyl attachment site [posttranslational modification]; other site
1104326004298	e3 binding domain; Region: E3_binding; pfam02817
1104326004299	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1104326004300	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1104326004301	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1104326004302	CoA-ligase; Region: Ligase_CoA; pfam00549
1104326004303	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1104326004304	CoA binding domain; Region: CoA_binding; smart00881
1104326004305	CoA-ligase; Region: Ligase_CoA; pfam00549
1104326004306	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1104326004307	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1104326004308	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1104326004309	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1104326004310	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1104326004311	hypothetical protein; Provisional; Region: PRK10588
1104326004312	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1104326004313	active site
1104326004314	colicin uptake protein TolQ; Provisional; Region: PRK10801
1104326004315	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1104326004316	colicin uptake protein TolR; Provisional; Region: PRK11024
1104326004317	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1104326004318	TolA C-terminal; Region: TolA; pfam06519
1104326004319	translocation protein TolB; Provisional; Region: tolB; PRK03629
1104326004320	TolB amino-terminal domain; Region: TolB_N; pfam04052
1104326004321	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1104326004322	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1104326004323	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1104326004324	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1104326004325	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326004326	ligand binding site [chemical binding]; other site
1104326004327	tol-pal system protein YbgF; Provisional; Region: PRK10803
1104326004328	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1104326004329	quinolinate synthetase; Provisional; Region: PRK09375
1104326004330	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1104326004331	zinc transporter ZitB; Provisional; Region: PRK03557
1104326004332	YbgS-like protein; Region: YbgS; pfam13985
1104326004333	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1104326004334	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1104326004335	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1104326004336	catalytic core [active]
1104326004337	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1104326004338	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1104326004339	active site
1104326004340	catalytic residues [active]
1104326004341	galactokinase; Provisional; Region: PRK05101
1104326004342	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1104326004343	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1104326004344	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1104326004345	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1104326004346	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1104326004347	dimer interface [polypeptide binding]; other site
1104326004348	active site
1104326004349	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1104326004350	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1104326004351	NAD binding site [chemical binding]; other site
1104326004352	homodimer interface [polypeptide binding]; other site
1104326004353	active site
1104326004354	substrate binding site [chemical binding]; other site
1104326004355	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1104326004356	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004357	Walker A/P-loop; other site
1104326004358	ATP binding site [chemical binding]; other site
1104326004359	Q-loop/lid; other site
1104326004360	ABC transporter signature motif; other site
1104326004361	Walker B; other site
1104326004362	D-loop; other site
1104326004363	H-loop/switch region; other site
1104326004364	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004365	Walker A/P-loop; other site
1104326004366	ATP binding site [chemical binding]; other site
1104326004367	Q-loop/lid; other site
1104326004368	ABC transporter signature motif; other site
1104326004369	Walker B; other site
1104326004370	D-loop; other site
1104326004371	H-loop/switch region; other site
1104326004372	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1104326004373	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1104326004374	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1104326004375	TOBE domain; Region: TOBE; pfam03459
1104326004376	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1104326004377	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1104326004378	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326004379	substrate binding pocket [chemical binding]; other site
1104326004380	membrane-bound complex binding site; other site
1104326004381	hinge residues; other site
1104326004382	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1104326004383	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004384	dimer interface [polypeptide binding]; other site
1104326004385	conserved gate region; other site
1104326004386	putative PBP binding loops; other site
1104326004387	ABC-ATPase subunit interface; other site
1104326004388	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1104326004389	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004390	Walker A/P-loop; other site
1104326004391	ATP binding site [chemical binding]; other site
1104326004392	Q-loop/lid; other site
1104326004393	ABC transporter signature motif; other site
1104326004394	Walker B; other site
1104326004395	D-loop; other site
1104326004396	H-loop/switch region; other site
1104326004397	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1104326004398	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1104326004399	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004400	active site
1104326004401	motif I; other site
1104326004402	motif II; other site
1104326004403	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004404	6-phosphogluconolactonase; Provisional; Region: PRK11028
1104326004405	acyl-CoA thioesterase; Provisional; Region: PRK10531
1104326004406	putative pectinesterase; Region: PLN02432; cl01911
1104326004407	imidazolonepropionase; Validated; Region: PRK09356
1104326004408	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1104326004409	active site
1104326004410	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1104326004411	putative active site [active]
1104326004412	putative metal binding site [ion binding]; other site
1104326004413	histidine utilization repressor; Provisional; Region: PRK14999
1104326004414	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326004415	DNA-binding site [nucleotide binding]; DNA binding site
1104326004416	UTRA domain; Region: UTRA; pfam07702
1104326004417	urocanate hydratase; Provisional; Region: PRK05414
1104326004418	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1104326004419	active sites [active]
1104326004420	tetramer interface [polypeptide binding]; other site
1104326004421	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1104326004422	substrate binding site [chemical binding]; other site
1104326004423	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1104326004424	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326004425	inhibitor-cofactor binding pocket; inhibition site
1104326004426	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326004427	catalytic residue [active]
1104326004428	biotin synthase; Provisional; Region: PRK15108
1104326004429	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326004430	FeS/SAM binding site; other site
1104326004431	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1104326004432	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1104326004433	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1104326004434	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326004435	catalytic residue [active]
1104326004436	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1104326004437	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326004438	S-adenosylmethionine binding site [chemical binding]; other site
1104326004439	AAA domain; Region: AAA_26; pfam13500
1104326004440	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
1104326004441	active site
1104326004442	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1104326004443	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004444	Walker A/P-loop; other site
1104326004445	ATP binding site [chemical binding]; other site
1104326004446	Q-loop/lid; other site
1104326004447	ABC transporter signature motif; other site
1104326004448	Walker B; other site
1104326004449	D-loop; other site
1104326004450	H-loop/switch region; other site
1104326004451	excinuclease ABC subunit B; Provisional; Region: PRK05298
1104326004452	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326004453	ATP binding site [chemical binding]; other site
1104326004454	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326004455	nucleotide binding region [chemical binding]; other site
1104326004456	ATP-binding site [chemical binding]; other site
1104326004457	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1104326004458	UvrB/uvrC motif; Region: UVR; pfam02151
1104326004459	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1104326004460	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1104326004461	phosphate binding site [ion binding]; other site
1104326004462	putative substrate binding pocket [chemical binding]; other site
1104326004463	dimer interface [polypeptide binding]; other site
1104326004464	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1104326004465	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326004466	FeS/SAM binding site; other site
1104326004467	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1104326004468	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1104326004469	MPT binding site; other site
1104326004470	trimer interface [polypeptide binding]; other site
1104326004471	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1104326004472	trimer interface [polypeptide binding]; other site
1104326004473	dimer interface [polypeptide binding]; other site
1104326004474	putative active site [active]
1104326004475	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1104326004476	MoaE interaction surface [polypeptide binding]; other site
1104326004477	MoeB interaction surface [polypeptide binding]; other site
1104326004478	thiocarboxylated glycine; other site
1104326004479	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1104326004480	MoaE homodimer interface [polypeptide binding]; other site
1104326004481	MoaD interaction [polypeptide binding]; other site
1104326004482	active site residues [active]
1104326004483	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1104326004484	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1104326004485	Predicted integral membrane protein [Function unknown]; Region: COG0392
1104326004486	cardiolipin synthase 2; Provisional; Region: PRK11263
1104326004487	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1104326004488	putative active site [active]
1104326004489	catalytic site [active]
1104326004490	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1104326004491	putative active site [active]
1104326004492	catalytic site [active]
1104326004493	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1104326004494	putative catalytic site [active]
1104326004495	putative metal binding site [ion binding]; other site
1104326004496	putative phosphate binding site [ion binding]; other site
1104326004497	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1104326004498	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1104326004499	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1104326004500	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1104326004501	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1104326004502	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1104326004503	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1104326004504	Walker A/P-loop; other site
1104326004505	ATP binding site [chemical binding]; other site
1104326004506	Q-loop/lid; other site
1104326004507	ABC transporter signature motif; other site
1104326004508	Walker B; other site
1104326004509	D-loop; other site
1104326004510	H-loop/switch region; other site
1104326004511	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1104326004512	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1104326004513	Walker A/P-loop; other site
1104326004514	ATP binding site [chemical binding]; other site
1104326004515	Q-loop/lid; other site
1104326004516	ABC transporter signature motif; other site
1104326004517	Walker B; other site
1104326004518	D-loop; other site
1104326004519	H-loop/switch region; other site
1104326004520	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1104326004521	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326004522	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326004523	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1104326004524	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326004525	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1104326004526	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1104326004527	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1104326004528	ATP binding site [chemical binding]; other site
1104326004529	Mg++ binding site [ion binding]; other site
1104326004530	motif III; other site
1104326004531	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326004532	nucleotide binding region [chemical binding]; other site
1104326004533	ATP-binding site [chemical binding]; other site
1104326004534	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
1104326004535	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1104326004536	DEAD_2; Region: DEAD_2; pfam06733
1104326004537	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1104326004538	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326004539	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326004540	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326004541	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326004542	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326004543	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326004544	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1104326004545	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326004546	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326004547	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326004548	glycosyl transferase family protein; Provisional; Region: PRK08136
1104326004549	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1104326004550	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1104326004551	active site
1104326004552	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1104326004553	hypothetical protein; Provisional; Region: PRK11019
1104326004554	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326004555	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1104326004556	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326004557	S-adenosylmethionine binding site [chemical binding]; other site
1104326004558	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1104326004559	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1104326004560	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1104326004561	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326004562	Walker A/P-loop; other site
1104326004563	ATP binding site [chemical binding]; other site
1104326004564	Q-loop/lid; other site
1104326004565	ABC transporter signature motif; other site
1104326004566	Walker B; other site
1104326004567	D-loop; other site
1104326004568	H-loop/switch region; other site
1104326004569	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326004570	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004571	dimer interface [polypeptide binding]; other site
1104326004572	conserved gate region; other site
1104326004573	putative PBP binding loops; other site
1104326004574	ABC-ATPase subunit interface; other site
1104326004575	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1104326004576	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326004577	substrate binding pocket [chemical binding]; other site
1104326004578	membrane-bound complex binding site; other site
1104326004579	hinge residues; other site
1104326004580	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1104326004581	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1104326004582	dimerization interface [polypeptide binding]; other site
1104326004583	DPS ferroxidase diiron center [ion binding]; other site
1104326004584	ion pore; other site
1104326004585	threonine and homoserine efflux system; Provisional; Region: PRK10532
1104326004586	EamA-like transporter family; Region: EamA; pfam00892
1104326004587	outer membrane protein X; Provisional; Region: ompX; PRK09408
1104326004588	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1104326004589	Sulfatase; Region: Sulfatase; pfam00884
1104326004590	manganese transport regulator MntR; Provisional; Region: PRK11050
1104326004591	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1104326004592	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1104326004593	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1104326004594	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1104326004595	transmembrane helices; other site
1104326004596	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1104326004597	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326004598	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326004599	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1104326004600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326004601	putative substrate translocation pore; other site
1104326004602	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326004603	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1104326004604	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326004605	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326004606	active site
1104326004607	catalytic tetrad [active]
1104326004608	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1104326004609	beta-galactosidase; Region: BGL; TIGR03356
1104326004610	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1104326004611	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1104326004612	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1104326004613	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326004614	DNA-binding site [nucleotide binding]; DNA binding site
1104326004615	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1104326004616	L,D-transpeptidase; Provisional; Region: PRK10260
1104326004617	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1104326004618	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326004619	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1104326004620	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326004621	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326004622	ABC transporter; Region: ABC_tran_2; pfam12848
1104326004623	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326004624	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1104326004625	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1104326004626	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
1104326004627	putative active site [active]
1104326004628	putative catalytic site [active]
1104326004629	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326004630	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326004631	putative substrate translocation pore; other site
1104326004632	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326004633	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326004634	DNA binding site [nucleotide binding]
1104326004635	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1104326004636	ligand binding site [chemical binding]; other site
1104326004637	dimerization interface [polypeptide binding]; other site
1104326004638	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1104326004639	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1104326004640	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004641	active site
1104326004642	motif I; other site
1104326004643	motif II; other site
1104326004644	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004645	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1104326004646	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1104326004647	dimer interface [polypeptide binding]; other site
1104326004648	active site
1104326004649	glycine loop; other site
1104326004650	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1104326004651	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326004652	FeS/SAM binding site; other site
1104326004653	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1104326004654	active site
1104326004655	intersubunit interactions; other site
1104326004656	catalytic residue [active]
1104326004657	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1104326004658	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1104326004659	ATP binding site [chemical binding]; other site
1104326004660	substrate interface [chemical binding]; other site
1104326004661	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1104326004662	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1104326004663	dimer interface [polypeptide binding]; other site
1104326004664	putative functional site; other site
1104326004665	putative MPT binding site; other site
1104326004666	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1104326004667	catalytic nucleophile [active]
1104326004668	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1104326004669	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326004670	Walker A/P-loop; other site
1104326004671	ATP binding site [chemical binding]; other site
1104326004672	Q-loop/lid; other site
1104326004673	ABC transporter signature motif; other site
1104326004674	Walker B; other site
1104326004675	D-loop; other site
1104326004676	H-loop/switch region; other site
1104326004677	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326004678	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326004679	Walker A/P-loop; other site
1104326004680	ATP binding site [chemical binding]; other site
1104326004681	Q-loop/lid; other site
1104326004682	ABC transporter signature motif; other site
1104326004683	Walker B; other site
1104326004684	D-loop; other site
1104326004685	H-loop/switch region; other site
1104326004686	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1104326004687	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1104326004688	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1104326004689	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1104326004690	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004691	dimer interface [polypeptide binding]; other site
1104326004692	conserved gate region; other site
1104326004693	putative PBP binding loops; other site
1104326004694	ABC-ATPase subunit interface; other site
1104326004695	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1104326004696	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1104326004697	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004698	dimer interface [polypeptide binding]; other site
1104326004699	conserved gate region; other site
1104326004700	putative PBP binding loops; other site
1104326004701	ABC-ATPase subunit interface; other site
1104326004702	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1104326004703	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1104326004704	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326004705	FeS/SAM binding site; other site
1104326004706	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1104326004707	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1104326004708	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1104326004709	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1104326004710	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1104326004711	putative C-terminal domain interface [polypeptide binding]; other site
1104326004712	putative GSH binding site (G-site) [chemical binding]; other site
1104326004713	putative dimer interface [polypeptide binding]; other site
1104326004714	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1104326004715	putative N-terminal domain interface [polypeptide binding]; other site
1104326004716	putative dimer interface [polypeptide binding]; other site
1104326004717	putative substrate binding pocket (H-site) [chemical binding]; other site
1104326004718	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1104326004719	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1104326004720	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1104326004721	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1104326004722	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1104326004723	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326004724	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1104326004725	active site
1104326004726	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1104326004727	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
1104326004728	active site
1104326004729	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1104326004730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326004731	putative substrate translocation pore; other site
1104326004732	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1104326004733	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004734	active site
1104326004735	motif I; other site
1104326004736	motif II; other site
1104326004737	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326004738	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1104326004739	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326004740	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326004741	putative substrate translocation pore; other site
1104326004742	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326004743	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326004744	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1104326004745	ArsC family; Region: ArsC; pfam03960
1104326004746	catalytic residues [active]
1104326004747	arsenical pump membrane protein; Provisional; Region: PRK15445
1104326004748	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1104326004749	transmembrane helices; other site
1104326004750	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326004751	dimerization interface [polypeptide binding]; other site
1104326004752	putative DNA binding site [nucleotide binding]; other site
1104326004753	putative Zn2+ binding site [ion binding]; other site
1104326004754	putative transporter; Provisional; Region: PRK04972
1104326004755	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1104326004756	TrkA-C domain; Region: TrkA_C; pfam02080
1104326004757	TrkA-C domain; Region: TrkA_C; pfam02080
1104326004758	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1104326004759	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1104326004760	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1104326004761	GSH binding site [chemical binding]; other site
1104326004762	catalytic residues [active]
1104326004763	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1104326004764	dimer interface [polypeptide binding]; other site
1104326004765	FMN binding site [chemical binding]; other site
1104326004766	NADPH bind site [chemical binding]; other site
1104326004767	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1104326004768	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1104326004769	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1104326004770	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1104326004771	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1104326004772	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1104326004773	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004774	Walker A/P-loop; other site
1104326004775	ATP binding site [chemical binding]; other site
1104326004776	Q-loop/lid; other site
1104326004777	ABC transporter signature motif; other site
1104326004778	Walker B; other site
1104326004779	D-loop; other site
1104326004780	H-loop/switch region; other site
1104326004781	TOBE domain; Region: TOBE_2; pfam08402
1104326004782	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1104326004783	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004784	dimer interface [polypeptide binding]; other site
1104326004785	conserved gate region; other site
1104326004786	putative PBP binding loops; other site
1104326004787	ABC-ATPase subunit interface; other site
1104326004788	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1104326004789	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004790	dimer interface [polypeptide binding]; other site
1104326004791	conserved gate region; other site
1104326004792	putative PBP binding loops; other site
1104326004793	ABC-ATPase subunit interface; other site
1104326004794	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1104326004795	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1104326004796	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326004797	S-adenosylmethionine binding site [chemical binding]; other site
1104326004798	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326004799	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326004800	active site
1104326004801	phosphorylation site [posttranslational modification]
1104326004802	intermolecular recognition site; other site
1104326004803	dimerization interface [polypeptide binding]; other site
1104326004804	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326004805	DNA binding site [nucleotide binding]
1104326004806	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326004807	dimer interface [polypeptide binding]; other site
1104326004808	phosphorylation site [posttranslational modification]
1104326004809	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326004810	ATP binding site [chemical binding]; other site
1104326004811	Mg2+ binding site [ion binding]; other site
1104326004812	G-X-G motif; other site
1104326004813	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326004814	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326004815	substrate binding pocket [chemical binding]; other site
1104326004816	membrane-bound complex binding site; other site
1104326004817	hinge residues; other site
1104326004818	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004819	dimer interface [polypeptide binding]; other site
1104326004820	conserved gate region; other site
1104326004821	putative PBP binding loops; other site
1104326004822	ABC-ATPase subunit interface; other site
1104326004823	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326004824	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326004825	dimer interface [polypeptide binding]; other site
1104326004826	conserved gate region; other site
1104326004827	putative PBP binding loops; other site
1104326004828	ABC-ATPase subunit interface; other site
1104326004829	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1104326004830	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326004831	substrate binding pocket [chemical binding]; other site
1104326004832	membrane-bound complex binding site; other site
1104326004833	hinge residues; other site
1104326004834	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1104326004835	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004836	Walker A/P-loop; other site
1104326004837	ATP binding site [chemical binding]; other site
1104326004838	Q-loop/lid; other site
1104326004839	ABC transporter signature motif; other site
1104326004840	Walker B; other site
1104326004841	D-loop; other site
1104326004842	H-loop/switch region; other site
1104326004843	putative lipoprotein; Provisional; Region: PRK10533
1104326004844	hypothetical protein; Provisional; Region: PRK02877
1104326004845	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1104326004846	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1104326004847	amidase catalytic site [active]
1104326004848	Zn binding residues [ion binding]; other site
1104326004849	substrate binding site [chemical binding]; other site
1104326004850	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1104326004851	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1104326004852	ligand binding site [chemical binding]; other site
1104326004853	flexible hinge region; other site
1104326004854	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
1104326004855	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1104326004856	type II secretion system protein C; Region: typeII_sec_gspC; TIGR01713
1104326004857	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1104326004858	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1104326004859	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1104326004860	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1104326004861	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1104326004862	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1104326004863	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1104326004864	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1104326004865	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1104326004866	Walker A motif; other site
1104326004867	ATP binding site [chemical binding]; other site
1104326004868	Walker B motif; other site
1104326004869	type II secretion system protein F; Region: GspF; TIGR02120
1104326004870	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1104326004871	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1104326004872	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1104326004873	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1104326004874	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1104326004875	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1104326004876	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1104326004877	Type II transport protein GspH; Region: GspH; pfam12019
1104326004878	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1104326004879	type II secretion system protein I; Region: gspI; TIGR01707
1104326004880	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1104326004881	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
1104326004882	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1104326004883	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1104326004884	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1104326004885	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
1104326004886	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
1104326004887	GspL periplasmic domain; Region: GspL_C; cl14909
1104326004888	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
1104326004889	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1104326004890	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1104326004891	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1104326004892	N-terminal Early set domain associated with the catalytic domain of chitinase; Region: E_set_Chitinase_N; cd02848
1104326004893	Glyco_18 domain; Region: Glyco_18; smart00636
1104326004894	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1104326004895	active site
1104326004896	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
1104326004897	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
1104326004898	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1104326004899	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1104326004900	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1104326004901	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1104326004902	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1104326004903	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326004904	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326004905	catalytic residue [active]
1104326004906	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1104326004907	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1104326004908	putative sugar binding site [chemical binding]; other site
1104326004909	catalytic residues [active]
1104326004910	PKD domain; Region: PKD; pfam00801
1104326004911	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
1104326004912	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1104326004913	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1104326004914	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326004915	NAD(P) binding site [chemical binding]; other site
1104326004916	active site
1104326004917	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1104326004918	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1104326004919	putative NAD(P) binding site [chemical binding]; other site
1104326004920	putative active site [active]
1104326004921	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1104326004922	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1104326004923	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1104326004924	tetramer interface [polypeptide binding]; other site
1104326004925	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326004926	catalytic residue [active]
1104326004927	pyruvate dehydrogenase; Provisional; Region: PRK09124
1104326004928	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1104326004929	PYR/PP interface [polypeptide binding]; other site
1104326004930	dimer interface [polypeptide binding]; other site
1104326004931	tetramer interface [polypeptide binding]; other site
1104326004932	TPP binding site [chemical binding]; other site
1104326004933	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326004934	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1104326004935	TPP-binding site [chemical binding]; other site
1104326004936	Predicted membrane protein [Function unknown]; Region: COG2259
1104326004937	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1104326004938	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1104326004939	FAD binding pocket [chemical binding]; other site
1104326004940	FAD binding motif [chemical binding]; other site
1104326004941	phosphate binding motif [ion binding]; other site
1104326004942	beta-alpha-beta structure motif; other site
1104326004943	NAD binding pocket [chemical binding]; other site
1104326004944	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326004945	catalytic loop [active]
1104326004946	iron binding site [ion binding]; other site
1104326004947	hybrid cluster protein; Provisional; Region: PRK05290
1104326004948	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1104326004949	ACS interaction site; other site
1104326004950	CODH interaction site; other site
1104326004951	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1104326004952	hybrid metal cluster; other site
1104326004953	Predicted membrane protein [Function unknown]; Region: COG2431
1104326004954	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1104326004955	amphipathic channel; other site
1104326004956	Asn-Pro-Ala signature motifs; other site
1104326004957	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1104326004958	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1104326004959	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1104326004960	putative active site [active]
1104326004961	putative metal-binding site [ion binding]; other site
1104326004962	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1104326004963	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1104326004964	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326004965	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326004966	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1104326004967	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1104326004968	Walker A/P-loop; other site
1104326004969	ATP binding site [chemical binding]; other site
1104326004970	Q-loop/lid; other site
1104326004971	ABC transporter signature motif; other site
1104326004972	Walker B; other site
1104326004973	D-loop; other site
1104326004974	H-loop/switch region; other site
1104326004975	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1104326004976	FtsX-like permease family; Region: FtsX; pfam02687
1104326004977	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1104326004978	DNA-binding site [nucleotide binding]; DNA binding site
1104326004979	RNA-binding motif; other site
1104326004980	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1104326004981	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1104326004982	Clp amino terminal domain; Region: Clp_N; pfam02861
1104326004983	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326004984	Walker A motif; other site
1104326004985	ATP binding site [chemical binding]; other site
1104326004986	Walker B motif; other site
1104326004987	arginine finger; other site
1104326004988	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326004989	Walker A motif; other site
1104326004990	ATP binding site [chemical binding]; other site
1104326004991	Walker B motif; other site
1104326004992	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1104326004993	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1104326004994	rRNA binding site [nucleotide binding]; other site
1104326004995	predicted 30S ribosome binding site; other site
1104326004996	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1104326004997	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1104326004998	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326004999	Walker A/P-loop; other site
1104326005000	ATP binding site [chemical binding]; other site
1104326005001	Q-loop/lid; other site
1104326005002	ABC transporter signature motif; other site
1104326005003	Walker B; other site
1104326005004	D-loop; other site
1104326005005	H-loop/switch region; other site
1104326005006	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1104326005007	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326005008	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326005009	Walker A/P-loop; other site
1104326005010	ATP binding site [chemical binding]; other site
1104326005011	Q-loop/lid; other site
1104326005012	ABC transporter signature motif; other site
1104326005013	Walker B; other site
1104326005014	D-loop; other site
1104326005015	H-loop/switch region; other site
1104326005016	thioredoxin reductase; Provisional; Region: PRK10262
1104326005017	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326005018	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326005019	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1104326005020	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326005021	putative DNA binding site [nucleotide binding]; other site
1104326005022	putative Zn2+ binding site [ion binding]; other site
1104326005023	AsnC family; Region: AsnC_trans_reg; pfam01037
1104326005024	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1104326005025	Protein of unknown function (DUF998); Region: DUF998; pfam06197
1104326005026	DNA translocase FtsK; Provisional; Region: PRK10263
1104326005027	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1104326005028	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1104326005029	periplasmic chaperone LolA; Region: lolA; TIGR00547
1104326005030	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1104326005031	recombination factor protein RarA; Reviewed; Region: PRK13342
1104326005032	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326005033	Walker A motif; other site
1104326005034	ATP binding site [chemical binding]; other site
1104326005035	Walker B motif; other site
1104326005036	arginine finger; other site
1104326005037	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1104326005038	seryl-tRNA synthetase; Provisional; Region: PRK05431
1104326005039	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1104326005040	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1104326005041	dimer interface [polypeptide binding]; other site
1104326005042	active site
1104326005043	motif 1; other site
1104326005044	motif 2; other site
1104326005045	motif 3; other site
1104326005046	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1104326005047	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1104326005048	putative [Fe4-S4] binding site [ion binding]; other site
1104326005049	putative molybdopterin cofactor binding site [chemical binding]; other site
1104326005050	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1104326005051	putative molybdopterin cofactor binding site; other site
1104326005052	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1104326005053	4Fe-4S binding domain; Region: Fer4; pfam00037
1104326005054	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1104326005055	putative MFS family transporter protein; Provisional; Region: PRK03633
1104326005056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326005057	putative substrate translocation pore; other site
1104326005058	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1104326005059	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1104326005060	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326005061	FeS/SAM binding site; other site
1104326005062	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1104326005063	Pyruvate formate lyase 1; Region: PFL1; cd01678
1104326005064	coenzyme A binding site [chemical binding]; other site
1104326005065	active site
1104326005066	catalytic residues [active]
1104326005067	glycine loop; other site
1104326005068	formate transporter; Provisional; Region: PRK10805
1104326005069	uncharacterized domain; Region: TIGR00702
1104326005070	YcaO-like family; Region: YcaO; pfam02624
1104326005071	Predicted membrane protein [Function unknown]; Region: COG2323
1104326005072	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1104326005073	homodimer interface [polypeptide binding]; other site
1104326005074	substrate-cofactor binding pocket; other site
1104326005075	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326005076	catalytic residue [active]
1104326005077	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1104326005078	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1104326005079	hinge; other site
1104326005080	active site
1104326005081	cytidylate kinase; Provisional; Region: cmk; PRK00023
1104326005082	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1104326005083	CMP-binding site; other site
1104326005084	The sites determining sugar specificity; other site
1104326005085	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1104326005086	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1104326005087	RNA binding site [nucleotide binding]; other site
1104326005088	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1104326005089	RNA binding site [nucleotide binding]; other site
1104326005090	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1104326005091	RNA binding site [nucleotide binding]; other site
1104326005092	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1104326005093	RNA binding site [nucleotide binding]; other site
1104326005094	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1104326005095	RNA binding site [nucleotide binding]; other site
1104326005096	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1104326005097	IHF dimer interface [polypeptide binding]; other site
1104326005098	IHF - DNA interface [nucleotide binding]; other site
1104326005099	ComEC family competence protein; Provisional; Region: PRK11539
1104326005100	Competence protein; Region: Competence; pfam03772
1104326005101	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1104326005102	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1104326005103	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326005104	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1104326005105	Walker A/P-loop; other site
1104326005106	ATP binding site [chemical binding]; other site
1104326005107	Q-loop/lid; other site
1104326005108	ABC transporter signature motif; other site
1104326005109	Walker B; other site
1104326005110	D-loop; other site
1104326005111	H-loop/switch region; other site
1104326005112	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1104326005113	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1104326005114	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1104326005115	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1104326005116	Trm112p-like protein; Region: Trm112p; cl01066
1104326005117	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1104326005118	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1104326005119	Ligand binding site; other site
1104326005120	oligomer interface; other site
1104326005121	hypothetical protein; Provisional; Region: PRK10593
1104326005122	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1104326005123	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1104326005124	putative active site [active]
1104326005125	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1104326005126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326005127	S-adenosylmethionine binding site [chemical binding]; other site
1104326005128	condesin subunit F; Provisional; Region: PRK05260
1104326005129	condesin subunit E; Provisional; Region: PRK05256
1104326005130	cell division protein MukB; Provisional; Region: mukB; PRK04863
1104326005131	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1104326005132	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1104326005133	murein L,D-transpeptidase; Provisional; Region: PRK10594
1104326005134	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1104326005135	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326005136	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326005137	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1104326005138	Peptidase M15; Region: Peptidase_M15_3; cl01194
1104326005139	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1104326005140	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1104326005141	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326005142	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326005143	homodimer interface [polypeptide binding]; other site
1104326005144	catalytic residue [active]
1104326005145	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326005146	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1104326005147	trimer interface [polypeptide binding]; other site
1104326005148	eyelet of channel; other site
1104326005149	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1104326005150	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1104326005151	putative dimer interface [polypeptide binding]; other site
1104326005152	putative anticodon binding site; other site
1104326005153	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1104326005154	homodimer interface [polypeptide binding]; other site
1104326005155	motif 1; other site
1104326005156	motif 2; other site
1104326005157	active site
1104326005158	motif 3; other site
1104326005159	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1104326005160	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1104326005161	active site
1104326005162	aminopeptidase N; Provisional; Region: pepN; PRK14015
1104326005163	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1104326005164	active site
1104326005165	Zn binding site [ion binding]; other site
1104326005166	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
1104326005167	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1104326005168	Walker A/P-loop; other site
1104326005169	ATP binding site [chemical binding]; other site
1104326005170	Q-loop/lid; other site
1104326005171	ABC transporter signature motif; other site
1104326005172	Walker B; other site
1104326005173	D-loop; other site
1104326005174	H-loop/switch region; other site
1104326005175	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1104326005176	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005177	dimer interface [polypeptide binding]; other site
1104326005178	conserved gate region; other site
1104326005179	putative PBP binding loops; other site
1104326005180	ABC-ATPase subunit interface; other site
1104326005181	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1104326005182	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1104326005183	active site
1104326005184	dimer interface [polypeptide binding]; other site
1104326005185	non-prolyl cis peptide bond; other site
1104326005186	insertion regions; other site
1104326005187	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1104326005188	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326005189	substrate binding pocket [chemical binding]; other site
1104326005190	membrane-bound complex binding site; other site
1104326005191	hinge residues; other site
1104326005192	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1104326005193	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1104326005194	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1104326005195	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1104326005196	quinone interaction residues [chemical binding]; other site
1104326005197	active site
1104326005198	catalytic residues [active]
1104326005199	FMN binding site [chemical binding]; other site
1104326005200	substrate binding site [chemical binding]; other site
1104326005201	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1104326005202	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1104326005203	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1104326005204	MOSC domain; Region: MOSC; pfam03473
1104326005205	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326005206	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1104326005207	catalytic loop [active]
1104326005208	iron binding site [ion binding]; other site
1104326005209	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1104326005210	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1104326005211	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1104326005212	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326005213	S-adenosylmethionine binding site [chemical binding]; other site
1104326005214	ABC transporter ATPase component; Reviewed; Region: PRK11147
1104326005215	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326005216	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326005217	Walker A/P-loop; other site
1104326005218	Walker A/P-loop; other site
1104326005219	ATP binding site [chemical binding]; other site
1104326005220	ATP binding site [chemical binding]; other site
1104326005221	Q-loop/lid; other site
1104326005222	Q-loop/lid; other site
1104326005223	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326005224	ABC transporter signature motif; other site
1104326005225	Walker B; other site
1104326005226	D-loop; other site
1104326005227	ABC transporter; Region: ABC_tran_2; pfam12848
1104326005228	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326005229	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1104326005230	Paraquat-inducible protein A; Region: PqiA; pfam04403
1104326005231	Paraquat-inducible protein A; Region: PqiA; pfam04403
1104326005232	paraquat-inducible protein B; Provisional; Region: PRK10807
1104326005233	mce related protein; Region: MCE; pfam02470
1104326005234	mce related protein; Region: MCE; pfam02470
1104326005235	mce related protein; Region: MCE; pfam02470
1104326005236	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1104326005237	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1104326005238	Ribosome modulation factor; Region: RMF; pfam04957
1104326005239	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1104326005240	active site 1 [active]
1104326005241	dimer interface [polypeptide binding]; other site
1104326005242	active site 2 [active]
1104326005243	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1104326005244	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1104326005245	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1104326005246	outer membrane protein A; Reviewed; Region: PRK10808
1104326005247	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1104326005248	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326005249	ligand binding site [chemical binding]; other site
1104326005250	SOS cell division inhibitor; Provisional; Region: PRK10595
1104326005251	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1104326005252	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1104326005253	TIGR01666 family membrane protein; Region: YCCS
1104326005254	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1104326005255	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1104326005256	Predicted membrane protein [Function unknown]; Region: COG3304
1104326005257	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1104326005258	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1104326005259	DNA helicase IV; Provisional; Region: helD; PRK11054
1104326005260	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1104326005261	Part of AAA domain; Region: AAA_19; pfam13245
1104326005262	Family description; Region: UvrD_C_2; pfam13538
1104326005263	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1104326005264	active site
1104326005265	dimer interfaces [polypeptide binding]; other site
1104326005266	catalytic residues [active]
1104326005267	hypothetical protein; Provisional; Region: PRK03641
1104326005268	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1104326005269	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1104326005270	heat shock protein HspQ; Provisional; Region: PRK14129
1104326005271	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1104326005272	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1104326005273	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1104326005274	putative RNA binding site [nucleotide binding]; other site
1104326005275	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326005276	S-adenosylmethionine binding site [chemical binding]; other site
1104326005277	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
1104326005278	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1104326005279	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1104326005280	catalytic residues [active]
1104326005281	catalytic nucleophile [active]
1104326005282	Recombinase; Region: Recombinase; pfam07508
1104326005283	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1104326005284	Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; pfam10137
1104326005285	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
1104326005286	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1104326005287	Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient...; Region: SR_Res_par; cd03767
1104326005288	catalytic residues [active]
1104326005289	catalytic nucleophile [active]
1104326005290	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1104326005291	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1104326005292	active site
1104326005293	tRNA_anti-like; Region: tRNA_anti-like; pfam12869
1104326005294	tRNA_anti-like; Region: tRNA_anti-like; pfam12869
1104326005295	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1104326005296	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1104326005297	substrate binding site [chemical binding]; other site
1104326005298	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326005299	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326005300	acylphosphatase; Provisional; Region: PRK14426
1104326005301	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1104326005302	sulfur transfer protein TusE; Provisional; Region: PRK11508
1104326005303	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1104326005304	YccA-like proteins; Region: YccA_like; cd10433
1104326005305	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1104326005306	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1104326005307	peptide binding site [polypeptide binding]; other site
1104326005308	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326005309	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326005310	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326005311	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326005312	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; pfam10022
1104326005313	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326005314	galactoside permease; Reviewed; Region: lacY; PRK09528
1104326005315	putative substrate translocation pore; other site
1104326005316	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1104326005317	DJ-1 family protein; Region: not_thiJ; TIGR01383
1104326005318	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1104326005319	conserved cys residue [active]
1104326005320	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1104326005321	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1104326005322	FMN-binding pocket [chemical binding]; other site
1104326005323	flavin binding motif; other site
1104326005324	phosphate binding motif [ion binding]; other site
1104326005325	beta-alpha-beta structure motif; other site
1104326005326	NAD binding pocket [chemical binding]; other site
1104326005327	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326005328	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1104326005329	catalytic loop [active]
1104326005330	iron binding site [ion binding]; other site
1104326005331	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1104326005332	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1104326005333	[2Fe-2S] cluster binding site [ion binding]; other site
1104326005334	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1104326005335	hydrophobic ligand binding site; other site
1104326005336	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
1104326005337	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1104326005338	OHCU decarboxylase; Region: UraD_2; TIGR03180
1104326005339	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1104326005340	active site
1104326005341	homotetramer interface [polypeptide binding]; other site
1104326005342	guanine deaminase; Provisional; Region: PRK09228
1104326005343	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1104326005344	active site
1104326005345	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
1104326005346	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1104326005347	Na binding site [ion binding]; other site
1104326005348	putative substrate binding site [chemical binding]; other site
1104326005349	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1104326005350	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326005351	DNA-binding site [nucleotide binding]; DNA binding site
1104326005352	FCD domain; Region: FCD; pfam07729
1104326005353	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1104326005354	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
1104326005355	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
1104326005356	active site
1104326005357	catalytic site [active]
1104326005358	tetramer interface [polypeptide binding]; other site
1104326005359	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
1104326005360	amidase; Provisional; Region: PRK09201
1104326005361	Amidase; Region: Amidase; pfam01425
1104326005362	Protein of unknown function (DUF4089); Region: DUF4089; pfam13318
1104326005363	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1104326005364	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1104326005365	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326005366	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326005367	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1104326005368	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326005369	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326005370	substrate binding pocket [chemical binding]; other site
1104326005371	membrane-bound complex binding site; other site
1104326005372	hinge residues; other site
1104326005373	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326005374	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005375	dimer interface [polypeptide binding]; other site
1104326005376	conserved gate region; other site
1104326005377	putative PBP binding loops; other site
1104326005378	ABC-ATPase subunit interface; other site
1104326005379	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005380	dimer interface [polypeptide binding]; other site
1104326005381	conserved gate region; other site
1104326005382	putative PBP binding loops; other site
1104326005383	ABC-ATPase subunit interface; other site
1104326005384	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1104326005385	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326005386	Walker A/P-loop; other site
1104326005387	ATP binding site [chemical binding]; other site
1104326005388	Q-loop/lid; other site
1104326005389	ABC transporter signature motif; other site
1104326005390	Walker B; other site
1104326005391	D-loop; other site
1104326005392	H-loop/switch region; other site
1104326005393	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1104326005394	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326005395	catalytic residue [active]
1104326005396	allantoate amidohydrolase; Reviewed; Region: PRK09290
1104326005397	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1104326005398	active site
1104326005399	metal binding site [ion binding]; metal-binding site
1104326005400	dimer interface [polypeptide binding]; other site
1104326005401	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1104326005402	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1104326005403	Walker A/P-loop; other site
1104326005404	ATP binding site [chemical binding]; other site
1104326005405	Q-loop/lid; other site
1104326005406	ABC transporter signature motif; other site
1104326005407	Walker B; other site
1104326005408	D-loop; other site
1104326005409	H-loop/switch region; other site
1104326005410	TOBE domain; Region: TOBE_2; pfam08402
1104326005411	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1104326005412	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1104326005413	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005414	dimer interface [polypeptide binding]; other site
1104326005415	conserved gate region; other site
1104326005416	ABC-ATPase subunit interface; other site
1104326005417	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1104326005418	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005419	dimer interface [polypeptide binding]; other site
1104326005420	conserved gate region; other site
1104326005421	putative PBP binding loops; other site
1104326005422	ABC-ATPase subunit interface; other site
1104326005423	Arabinogalactan endo-1,4-beta-galactosidase [Carbohydrate transport and metabolism]; Region: COG3867
1104326005424	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1104326005425	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1104326005426	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1104326005427	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1104326005428	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326005429	active site turn [active]
1104326005430	phosphorylation site [posttranslational modification]
1104326005431	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1104326005432	trimer interface; other site
1104326005433	sugar binding site [chemical binding]; other site
1104326005434	lac repressor; Reviewed; Region: lacI; PRK09526
1104326005435	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326005436	DNA binding site [nucleotide binding]
1104326005437	domain linker motif; other site
1104326005438	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1104326005439	ligand binding site [chemical binding]; other site
1104326005440	dimerization interface (open form) [polypeptide binding]; other site
1104326005441	dimerization interface (closed form) [polypeptide binding]; other site
1104326005442	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1104326005443	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1104326005444	Divalent cation transporter; Region: MgtE; pfam01769
1104326005445	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1104326005446	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1104326005447	short chain dehydrogenase; Provisional; Region: PRK06500
1104326005448	classical (c) SDRs; Region: SDR_c; cd05233
1104326005449	NAD(P) binding site [chemical binding]; other site
1104326005450	active site
1104326005451	Predicted transcriptional regulators [Transcription]; Region: COG1733
1104326005452	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1104326005453	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1104326005454	classical (c) SDRs; Region: SDR_c; cd05233
1104326005455	NAD(P) binding site [chemical binding]; other site
1104326005456	active site
1104326005457	Predicted transcriptional regulators [Transcription]; Region: COG1733
1104326005458	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1104326005459	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1104326005460	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1104326005461	catalytic core [active]
1104326005462	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1104326005463	hypothetical protein; Provisional; Region: PRK10174
1104326005464	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1104326005465	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1104326005466	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1104326005467	EamA-like transporter family; Region: EamA; pfam00892
1104326005468	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1104326005469	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1104326005470	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1104326005471	putative FMN binding site [chemical binding]; other site
1104326005472	pyrimidine utilization protein D; Region: RutD; TIGR03611
1104326005473	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1104326005474	homotrimer interaction site [polypeptide binding]; other site
1104326005475	putative active site [active]
1104326005476	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326005477	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1104326005478	catalytic triad [active]
1104326005479	conserved cis-peptide bond; other site
1104326005480	pyrimidine utilization protein A; Region: RutA; TIGR03612
1104326005481	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1104326005482	active site
1104326005483	dimer interface [polypeptide binding]; other site
1104326005484	non-prolyl cis peptide bond; other site
1104326005485	insertion regions; other site
1104326005486	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1104326005487	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1104326005488	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326005489	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1104326005490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1104326005491	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1104326005492	Predicted transcriptional regulator [Transcription]; Region: COG3905
1104326005493	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1104326005494	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1104326005495	Glutamate binding site [chemical binding]; other site
1104326005496	NAD binding site [chemical binding]; other site
1104326005497	catalytic residues [active]
1104326005498	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1104326005499	Na binding site [ion binding]; other site
1104326005500	Protein of unknown function (DUF3574); Region: DUF3574; pfam12098
1104326005501	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1104326005502	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1104326005503	Nucleoside recognition; Region: Gate; pfam07670
1104326005504	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1104326005505	FTR1 family protein; Region: TIGR00145
1104326005506	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1104326005507	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1104326005508	Imelysin; Region: Peptidase_M75; pfam09375
1104326005509	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1104326005510	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1104326005511	hypothetical protein; Provisional; Region: PRK10536
1104326005512	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1104326005513	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1104326005514	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1104326005515	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326005516	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1104326005517	catalytic triad [active]
1104326005518	dimer interface [polypeptide binding]; other site
1104326005519	conserved cis-peptide bond; other site
1104326005520	Pirin-related protein [General function prediction only]; Region: COG1741
1104326005521	Pirin; Region: Pirin; pfam02678
1104326005522	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1104326005523	LysR family transcriptional regulator; Provisional; Region: PRK14997
1104326005524	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326005525	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1104326005526	putative effector binding pocket; other site
1104326005527	putative dimerization interface [polypeptide binding]; other site
1104326005528	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1104326005529	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1104326005530	putative ligand binding site [chemical binding]; other site
1104326005531	NAD binding site [chemical binding]; other site
1104326005532	dimerization interface [polypeptide binding]; other site
1104326005533	catalytic site [active]
1104326005534	putative hydrolase; Validated; Region: PRK09248
1104326005535	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1104326005536	active site
1104326005537	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1104326005538	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1104326005539	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1104326005540	curli assembly protein CsgF; Provisional; Region: PRK10050
1104326005541	curli assembly protein CsgE; Provisional; Region: PRK10386
1104326005542	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1104326005543	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326005544	DNA binding residues [nucleotide binding]
1104326005545	dimerization interface [polypeptide binding]; other site
1104326005546	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1104326005547	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1104326005548	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1104326005549	major curlin subunit; Provisional; Region: csgA; PRK10051
1104326005550	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1104326005551	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1104326005552	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1104326005553	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1104326005554	putative ADP-ribose binding site [chemical binding]; other site
1104326005555	putative active site [active]
1104326005556	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1104326005557	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1104326005558	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1104326005559	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1104326005560	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1104326005561	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1104326005562	Ligand binding site; other site
1104326005563	DXD motif; other site
1104326005564	lipoprotein; Provisional; Region: PRK10175
1104326005565	secY/secA suppressor protein; Provisional; Region: PRK11467
1104326005566	drug efflux system protein MdtG; Provisional; Region: PRK09874
1104326005567	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326005568	putative substrate translocation pore; other site
1104326005569	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1104326005570	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1104326005571	putative acyl-acceptor binding pocket; other site
1104326005572	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1104326005573	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1104326005574	active site residue [active]
1104326005575	hypothetical protein; Provisional; Region: PRK03757
1104326005576	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1104326005577	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1104326005578	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1104326005579	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1104326005580	DNA damage-inducible protein I; Provisional; Region: PRK10597
1104326005581	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1104326005582	active site
1104326005583	substrate binding pocket [chemical binding]; other site
1104326005584	dimer interface [polypeptide binding]; other site
1104326005585	lipoprotein; Provisional; Region: PRK10598
1104326005586	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1104326005587	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326005588	putative substrate translocation pore; other site
1104326005589	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1104326005590	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1104326005591	hypothetical protein; Provisional; Region: PRK11239
1104326005592	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1104326005593	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326005594	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326005595	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1104326005596	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1104326005597	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1104326005598	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1104326005599	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1104326005600	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1104326005601	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1104326005602	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1104326005603	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1104326005604	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1104326005605	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326005606	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326005607	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1104326005608	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1104326005609	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1104326005610	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1104326005611	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326005612	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1104326005613	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326005614	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1104326005615	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326005616	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1104326005617	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1104326005618	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326005619	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326005620	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1104326005621	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1104326005622	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1104326005623	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1104326005624	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1104326005625	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1104326005626	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1104326005627	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1104326005628	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326005629	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1104326005630	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1104326005631	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1104326005632	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1104326005633	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326005634	putative substrate translocation pore; other site
1104326005635	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326005636	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326005637	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326005638	putative effector binding pocket; other site
1104326005639	dimerization interface [polypeptide binding]; other site
1104326005640	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1104326005641	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1104326005642	homodimer interface [polypeptide binding]; other site
1104326005643	oligonucleotide binding site [chemical binding]; other site
1104326005644	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1104326005645	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1104326005646	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326005647	RNA binding surface [nucleotide binding]; other site
1104326005648	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1104326005649	active site
1104326005650	Maf-like protein; Region: Maf; pfam02545
1104326005651	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1104326005652	active site
1104326005653	dimer interface [polypeptide binding]; other site
1104326005654	hypothetical protein; Provisional; Region: PRK11193
1104326005655	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1104326005656	putative phosphate acyltransferase; Provisional; Region: PRK05331
1104326005657	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1104326005658	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1104326005659	dimer interface [polypeptide binding]; other site
1104326005660	active site
1104326005661	CoA binding pocket [chemical binding]; other site
1104326005662	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1104326005663	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1104326005664	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1104326005665	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1104326005666	NAD(P) binding site [chemical binding]; other site
1104326005667	homotetramer interface [polypeptide binding]; other site
1104326005668	homodimer interface [polypeptide binding]; other site
1104326005669	active site
1104326005670	acyl carrier protein; Provisional; Region: acpP; PRK00982
1104326005671	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1104326005672	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1104326005673	dimer interface [polypeptide binding]; other site
1104326005674	active site
1104326005675	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1104326005676	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1104326005677	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326005678	catalytic residue [active]
1104326005679	conserved hypothetical protein, YceG family; Region: TIGR00247
1104326005680	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1104326005681	dimerization interface [polypeptide binding]; other site
1104326005682	thymidylate kinase; Validated; Region: tmk; PRK00698
1104326005683	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1104326005684	TMP-binding site; other site
1104326005685	ATP-binding site [chemical binding]; other site
1104326005686	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1104326005687	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1104326005688	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1104326005689	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1104326005690	active site
1104326005691	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1104326005692	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326005693	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326005694	active site turn [active]
1104326005695	phosphorylation site [posttranslational modification]
1104326005696	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1104326005697	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326005698	N-terminal plug; other site
1104326005699	ligand-binding site [chemical binding]; other site
1104326005700	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1104326005701	nucleotide binding site/active site [active]
1104326005702	HIT family signature motif; other site
1104326005703	catalytic residue [active]
1104326005704	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1104326005705	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1104326005706	putative dimer interface [polypeptide binding]; other site
1104326005707	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1104326005708	thiamine kinase; Region: ycfN_thiK; TIGR02721
1104326005709	thiamine kinase; Provisional; Region: thiK; PRK10271
1104326005710	substrate binding site [chemical binding]; other site
1104326005711	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1104326005712	beta-hexosaminidase; Provisional; Region: PRK05337
1104326005713	hypothetical protein; Provisional; Region: PRK04940
1104326005714	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1104326005715	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326005716	hypothetical protein; Provisional; Region: PRK11280
1104326005717	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326005718	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326005719	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326005720	L,D-transpeptidase; Provisional; Region: PRK10190
1104326005721	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326005722	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326005723	transcription-repair coupling factor; Provisional; Region: PRK10689
1104326005724	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1104326005725	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326005726	ATP binding site [chemical binding]; other site
1104326005727	putative Mg++ binding site [ion binding]; other site
1104326005728	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326005729	nucleotide binding region [chemical binding]; other site
1104326005730	ATP-binding site [chemical binding]; other site
1104326005731	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1104326005732	Predicted membrane protein [Function unknown]; Region: COG4763
1104326005733	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1104326005734	potential frameshift: common BLAST hit: gi|296102866|ref|YP_003613012.1| lipoprotein-releasing system transmembrane protein
1104326005735	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1104326005736	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1104326005737	Walker A/P-loop; other site
1104326005738	ATP binding site [chemical binding]; other site
1104326005739	Q-loop/lid; other site
1104326005740	ABC transporter signature motif; other site
1104326005741	Walker B; other site
1104326005742	D-loop; other site
1104326005743	H-loop/switch region; other site
1104326005744	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1104326005745	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1104326005746	FtsX-like permease family; Region: FtsX; pfam02687
1104326005747	fructokinase; Reviewed; Region: PRK09557
1104326005748	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1104326005749	nucleotide binding site [chemical binding]; other site
1104326005750	potential frameshift: common BLAST hit: gi|296102862|ref|YP_003613008.1| NAD-dependent deacetylase
1104326005751	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
1104326005752	EAL domain; Region: EAL; pfam00563
1104326005753	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1104326005754	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1104326005755	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1104326005756	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005757	dimer interface [polypeptide binding]; other site
1104326005758	conserved gate region; other site
1104326005759	putative PBP binding loops; other site
1104326005760	ABC-ATPase subunit interface; other site
1104326005761	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005762	dimer interface [polypeptide binding]; other site
1104326005763	conserved gate region; other site
1104326005764	putative PBP binding loops; other site
1104326005765	ABC-ATPase subunit interface; other site
1104326005766	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1104326005767	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326005768	Walker A/P-loop; other site
1104326005769	ATP binding site [chemical binding]; other site
1104326005770	Q-loop/lid; other site
1104326005771	ABC transporter signature motif; other site
1104326005772	Walker B; other site
1104326005773	D-loop; other site
1104326005774	H-loop/switch region; other site
1104326005775	TOBE domain; Region: TOBE_2; pfam08402
1104326005776	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1104326005777	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1104326005778	metal binding site [ion binding]; metal-binding site
1104326005779	dimer interface [polypeptide binding]; other site
1104326005780	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1104326005781	sensor protein PhoQ; Provisional; Region: PRK10815
1104326005782	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1104326005783	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1104326005784	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326005785	ATP binding site [chemical binding]; other site
1104326005786	Mg2+ binding site [ion binding]; other site
1104326005787	G-X-G motif; other site
1104326005788	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1104326005789	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326005790	active site
1104326005791	phosphorylation site [posttranslational modification]
1104326005792	intermolecular recognition site; other site
1104326005793	dimerization interface [polypeptide binding]; other site
1104326005794	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326005795	DNA binding site [nucleotide binding]
1104326005796	adenylosuccinate lyase; Provisional; Region: PRK09285
1104326005797	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1104326005798	tetramer interface [polypeptide binding]; other site
1104326005799	active site
1104326005800	putative lysogenization regulator; Reviewed; Region: PRK00218
1104326005801	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1104326005802	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1104326005803	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1104326005804	nudix motif; other site
1104326005805	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1104326005806	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1104326005807	probable active site [active]
1104326005808	isocitrate dehydrogenase; Validated; Region: PRK07362
1104326005809	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1104326005810	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1104326005811	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326005812	dimerization interface [polypeptide binding]; other site
1104326005813	DNA binding residues [nucleotide binding]
1104326005814	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326005815	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1104326005816	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1104326005817	YCII-related domain; Region: YCII; cl00999
1104326005818	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1104326005819	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1104326005820	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326005821	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1104326005822	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1104326005823	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
1104326005824	conserved cys residue [active]
1104326005825	MarR family; Region: MarR_2; cl17246
1104326005826	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326005827	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1104326005828	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326005829	active site
1104326005830	phosphorylation site [posttranslational modification]
1104326005831	intermolecular recognition site; other site
1104326005832	dimerization interface [polypeptide binding]; other site
1104326005833	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326005834	DNA binding residues [nucleotide binding]
1104326005835	dimerization interface [polypeptide binding]; other site
1104326005836	BCCT family transporter; Region: BCCT; cl00569
1104326005837	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
1104326005838	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
1104326005839	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1104326005840	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1104326005841	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326005842	Cache domain; Region: Cache_1; pfam02743
1104326005843	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326005844	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326005845	metal binding site [ion binding]; metal-binding site
1104326005846	active site
1104326005847	I-site; other site
1104326005848	hypothetical protein; Provisional; Region: PRK10457
1104326005849	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1104326005850	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1104326005851	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326005852	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326005853	metal binding site [ion binding]; metal-binding site
1104326005854	active site
1104326005855	I-site; other site
1104326005856	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1104326005857	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1104326005858	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1104326005859	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1104326005860	hypothetical protein; Validated; Region: PRK06186
1104326005861	conserved cys residue [active]
1104326005862	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1104326005863	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326005864	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326005865	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326005866	Predicted membrane protein [Function unknown]; Region: COG2707
1104326005867	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1104326005868	putative deacylase active site [active]
1104326005869	hypothetical protein; Provisional; Region: PRK05325
1104326005870	PrkA family serine protein kinase; Provisional; Region: PRK15455
1104326005871	AAA ATPase domain; Region: AAA_16; pfam13191
1104326005872	Walker A motif; other site
1104326005873	ATP binding site [chemical binding]; other site
1104326005874	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1104326005875	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1104326005876	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1104326005877	active site
1104326005878	phosphate binding residues; other site
1104326005879	catalytic residues [active]
1104326005880	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1104326005881	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1104326005882	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1104326005883	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1104326005884	SelR domain; Region: SelR; pfam01641
1104326005885	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1104326005886	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1104326005887	Glyco_18 domain; Region: Glyco_18; smart00636
1104326005888	active site
1104326005889	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1104326005890	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1104326005891	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326005892	catalytic triad [active]
1104326005893	metal binding site [ion binding]; metal-binding site
1104326005894	conserved cis-peptide bond; other site
1104326005895	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1104326005896	active site
1104326005897	homodimer interface [polypeptide binding]; other site
1104326005898	protease 4; Provisional; Region: PRK10949
1104326005899	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1104326005900	tandem repeat interface [polypeptide binding]; other site
1104326005901	oligomer interface [polypeptide binding]; other site
1104326005902	active site residues [active]
1104326005903	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1104326005904	tandem repeat interface [polypeptide binding]; other site
1104326005905	oligomer interface [polypeptide binding]; other site
1104326005906	active site residues [active]
1104326005907	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1104326005908	putative FMN binding site [chemical binding]; other site
1104326005909	selenophosphate synthetase; Provisional; Region: PRK00943
1104326005910	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1104326005911	dimerization interface [polypeptide binding]; other site
1104326005912	putative ATP binding site [chemical binding]; other site
1104326005913	DNA topoisomerase III; Provisional; Region: PRK07726
1104326005914	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1104326005915	active site
1104326005916	putative interdomain interaction site [polypeptide binding]; other site
1104326005917	putative metal-binding site [ion binding]; other site
1104326005918	putative nucleotide binding site [chemical binding]; other site
1104326005919	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1104326005920	domain I; other site
1104326005921	DNA binding groove [nucleotide binding]
1104326005922	phosphate binding site [ion binding]; other site
1104326005923	domain II; other site
1104326005924	domain III; other site
1104326005925	nucleotide binding site [chemical binding]; other site
1104326005926	catalytic site [active]
1104326005927	domain IV; other site
1104326005928	glutamate dehydrogenase; Provisional; Region: PRK09414
1104326005929	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1104326005930	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1104326005931	NAD(P) binding site [chemical binding]; other site
1104326005932	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1104326005933	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1104326005934	active site
1104326005935	8-oxo-dGMP binding site [chemical binding]; other site
1104326005936	nudix motif; other site
1104326005937	metal binding site [ion binding]; metal-binding site
1104326005938	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1104326005939	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1104326005940	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1104326005941	Rhodanese Homology Domain; Region: RHOD; smart00450
1104326005942	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1104326005943	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1104326005944	active site residue [active]
1104326005945	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1104326005946	active site residue [active]
1104326005947	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
1104326005948	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326005949	Walker A/P-loop; other site
1104326005950	ATP binding site [chemical binding]; other site
1104326005951	Q-loop/lid; other site
1104326005952	ABC transporter signature motif; other site
1104326005953	Walker B; other site
1104326005954	D-loop; other site
1104326005955	H-loop/switch region; other site
1104326005956	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
1104326005957	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326005958	dimer interface [polypeptide binding]; other site
1104326005959	conserved gate region; other site
1104326005960	putative PBP binding loops; other site
1104326005961	ABC-ATPase subunit interface; other site
1104326005962	hypothetical protein; Provisional; Region: PRK11622
1104326005963	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
1104326005964	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1104326005965	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1104326005966	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1104326005967	putative catalytic site [active]
1104326005968	putative phosphate binding site [ion binding]; other site
1104326005969	active site
1104326005970	metal binding site A [ion binding]; metal-binding site
1104326005971	DNA binding site [nucleotide binding]
1104326005972	putative AP binding site [nucleotide binding]; other site
1104326005973	putative metal binding site B [ion binding]; other site
1104326005974	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1104326005975	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326005976	inhibitor-cofactor binding pocket; inhibition site
1104326005977	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326005978	catalytic residue [active]
1104326005979	arginine succinyltransferase; Provisional; Region: PRK10456
1104326005980	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1104326005981	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1104326005982	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1104326005983	NAD(P) binding site [chemical binding]; other site
1104326005984	catalytic residues [active]
1104326005985	succinylarginine dihydrolase; Provisional; Region: PRK13281
1104326005986	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1104326005987	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1104326005988	putative active site [active]
1104326005989	Zn binding site [ion binding]; other site
1104326005990	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1104326005991	dimer interface [polypeptide binding]; other site
1104326005992	hypothetical protein; Provisional; Region: PRK11396
1104326005993	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1104326005994	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1104326005995	GIY-YIG motif/motif A; other site
1104326005996	active site
1104326005997	catalytic site [active]
1104326005998	putative DNA binding site [nucleotide binding]; other site
1104326005999	metal binding site [ion binding]; metal-binding site
1104326006000	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1104326006001	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1104326006002	homodimer interface [polypeptide binding]; other site
1104326006003	NAD binding pocket [chemical binding]; other site
1104326006004	ATP binding pocket [chemical binding]; other site
1104326006005	Mg binding site [ion binding]; other site
1104326006006	active-site loop [active]
1104326006007	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1104326006008	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1104326006009	active site
1104326006010	P-loop; other site
1104326006011	phosphorylation site [posttranslational modification]
1104326006012	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1104326006013	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1104326006014	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1104326006015	methionine cluster; other site
1104326006016	active site
1104326006017	phosphorylation site [posttranslational modification]
1104326006018	metal binding site [ion binding]; metal-binding site
1104326006019	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1104326006020	Cupin domain; Region: Cupin_2; pfam07883
1104326006021	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1104326006022	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1104326006023	NAD binding site [chemical binding]; other site
1104326006024	sugar binding site [chemical binding]; other site
1104326006025	divalent metal binding site [ion binding]; other site
1104326006026	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1104326006027	dimer interface [polypeptide binding]; other site
1104326006028	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1104326006029	putative active site [active]
1104326006030	YdjC motif; other site
1104326006031	Mg binding site [ion binding]; other site
1104326006032	putative homodimer interface [polypeptide binding]; other site
1104326006033	hydroperoxidase II; Provisional; Region: katE; PRK11249
1104326006034	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1104326006035	tetramer interface [polypeptide binding]; other site
1104326006036	heme binding pocket [chemical binding]; other site
1104326006037	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1104326006038	domain interactions; other site
1104326006039	cell division modulator; Provisional; Region: PRK10113
1104326006040	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1104326006041	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1104326006042	inner membrane protein; Provisional; Region: PRK11648
1104326006043	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1104326006044	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1104326006045	NADP binding site [chemical binding]; other site
1104326006046	homodimer interface [polypeptide binding]; other site
1104326006047	active site
1104326006048	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1104326006049	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326006050	active site
1104326006051	motif I; other site
1104326006052	motif II; other site
1104326006053	YniB-like protein; Region: YniB; pfam14002
1104326006054	Phosphotransferase enzyme family; Region: APH; pfam01636
1104326006055	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1104326006056	active site
1104326006057	ATP binding site [chemical binding]; other site
1104326006058	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1104326006059	active site
1104326006060	ATP binding site [chemical binding]; other site
1104326006061	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1104326006062	6-phosphofructokinase 2; Provisional; Region: PRK10294
1104326006063	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1104326006064	putative substrate binding site [chemical binding]; other site
1104326006065	putative ATP binding site [chemical binding]; other site
1104326006066	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1104326006067	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1104326006068	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1104326006069	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1104326006070	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1104326006071	active site
1104326006072	dimer interface [polypeptide binding]; other site
1104326006073	motif 1; other site
1104326006074	motif 2; other site
1104326006075	motif 3; other site
1104326006076	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1104326006077	anticodon binding site; other site
1104326006078	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1104326006079	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1104326006080	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1104326006081	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1104326006082	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1104326006083	23S rRNA binding site [nucleotide binding]; other site
1104326006084	L21 binding site [polypeptide binding]; other site
1104326006085	L13 binding site [polypeptide binding]; other site
1104326006086	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1104326006087	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1104326006088	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1104326006089	dimer interface [polypeptide binding]; other site
1104326006090	motif 1; other site
1104326006091	active site
1104326006092	motif 2; other site
1104326006093	motif 3; other site
1104326006094	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1104326006095	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1104326006096	putative tRNA-binding site [nucleotide binding]; other site
1104326006097	B3/4 domain; Region: B3_4; pfam03483
1104326006098	tRNA synthetase B5 domain; Region: B5; smart00874
1104326006099	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1104326006100	dimer interface [polypeptide binding]; other site
1104326006101	motif 1; other site
1104326006102	motif 3; other site
1104326006103	motif 2; other site
1104326006104	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1104326006105	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1104326006106	IHF dimer interface [polypeptide binding]; other site
1104326006107	IHF - DNA interface [nucleotide binding]; other site
1104326006108	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1104326006109	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326006110	ABC-ATPase subunit  interface; other site
1104326006111	dimer interface [polypeptide binding]; other site
1104326006112	putative PBP binding regions; other site
1104326006113	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1104326006114	catalytic residues [active]
1104326006115	dimer interface [polypeptide binding]; other site
1104326006116	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1104326006117	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1104326006118	Walker A/P-loop; other site
1104326006119	ATP binding site [chemical binding]; other site
1104326006120	Q-loop/lid; other site
1104326006121	ABC transporter signature motif; other site
1104326006122	Walker B; other site
1104326006123	D-loop; other site
1104326006124	H-loop/switch region; other site
1104326006125	NlpC/P60 family; Region: NLPC_P60; pfam00877
1104326006126	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1104326006127	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1104326006128	hypothetical protein; Validated; Region: PRK00029
1104326006129	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
1104326006130	d-3-hydroxybutyrate dehydrogenase (HBDH), classical (c) SDRs; Region: HBDH_SDR_c; cd08940
1104326006131	NAD binding site [chemical binding]; other site
1104326006132	homotetramer interface [polypeptide binding]; other site
1104326006133	homodimer interface [polypeptide binding]; other site
1104326006134	substrate binding site [chemical binding]; other site
1104326006135	active site
1104326006136	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1104326006137	putative acyltransferase; Provisional; Region: PRK05790
1104326006138	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1104326006139	dimer interface [polypeptide binding]; other site
1104326006140	active site
1104326006141	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1104326006142	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1104326006143	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326006144	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006145	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1104326006146	putative dimerization interface [polypeptide binding]; other site
1104326006147	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
1104326006148	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1104326006149	Walker A/P-loop; other site
1104326006150	ATP binding site [chemical binding]; other site
1104326006151	Q-loop/lid; other site
1104326006152	ABC transporter signature motif; other site
1104326006153	Walker B; other site
1104326006154	D-loop; other site
1104326006155	H-loop/switch region; other site
1104326006156	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1104326006157	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326006158	ABC-ATPase subunit  interface; other site
1104326006159	dimer interface [polypeptide binding]; other site
1104326006160	putative PBP binding regions; other site
1104326006161	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1104326006162	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1104326006163	intersubunit interface [polypeptide binding]; other site
1104326006164	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
1104326006165	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1104326006166	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1104326006167	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
1104326006168	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326006169	N-terminal plug; other site
1104326006170	ligand-binding site [chemical binding]; other site
1104326006171	Hemin uptake protein hemP; Region: hemP; cl10043
1104326006172	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1104326006173	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1104326006174	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1104326006175	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1104326006176	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1104326006177	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1104326006178	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1104326006179	putative symporter YagG; Provisional; Region: PRK09669
1104326006180	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326006181	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1104326006182	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1104326006183	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1104326006184	putative inner membrane protein; Provisional; Region: PRK10983
1104326006185	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1104326006186	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1104326006187	FAD binding domain; Region: FAD_binding_4; pfam01565
1104326006188	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1104326006189	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1104326006190	CoenzymeA binding site [chemical binding]; other site
1104326006191	subunit interaction site [polypeptide binding]; other site
1104326006192	PHB binding site; other site
1104326006193	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1104326006194	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1104326006195	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
1104326006196	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1104326006197	ligand binding site [chemical binding]; other site
1104326006198	flexible hinge region; other site
1104326006199	Fimbrial protein; Region: Fimbrial; cl01416
1104326006200	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326006201	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1104326006202	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326006203	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326006204	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326006205	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326006206	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326006207	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1104326006208	Fimbrial protein; Region: Fimbrial; cl01416
1104326006209	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1104326006210	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326006211	DNA binding residues [nucleotide binding]
1104326006212	dimerization interface [polypeptide binding]; other site
1104326006213	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1104326006214	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1104326006215	[4Fe-4S] binding site [ion binding]; other site
1104326006216	molybdopterin cofactor binding site; other site
1104326006217	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1104326006218	molybdopterin cofactor binding site; other site
1104326006219	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1104326006220	Sensors of blue-light using FAD; Region: BLUF; smart01034
1104326006221	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326006222	transcriptional regulator MirA; Provisional; Region: PRK15043
1104326006223	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1104326006224	DNA binding residues [nucleotide binding]
1104326006225	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1104326006226	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1104326006227	putative ABC transporter; Region: ycf24; CHL00085
1104326006228	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1104326006229	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1104326006230	Walker A/P-loop; other site
1104326006231	ATP binding site [chemical binding]; other site
1104326006232	Q-loop/lid; other site
1104326006233	ABC transporter signature motif; other site
1104326006234	Walker B; other site
1104326006235	D-loop; other site
1104326006236	H-loop/switch region; other site
1104326006237	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1104326006238	FeS assembly protein SufD; Region: sufD; TIGR01981
1104326006239	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1104326006240	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1104326006241	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326006242	catalytic residue [active]
1104326006243	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1104326006244	L,D-transpeptidase; Provisional; Region: PRK10260
1104326006245	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326006246	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326006247	murein lipoprotein; Provisional; Region: PRK15396
1104326006248	pyruvate kinase; Provisional; Region: PRK09206
1104326006249	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1104326006250	domain interfaces; other site
1104326006251	active site
1104326006252	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1104326006253	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1104326006254	homodimer interface [polypeptide binding]; other site
1104326006255	substrate-cofactor binding pocket; other site
1104326006256	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326006257	catalytic residue [active]
1104326006258	cystathionine beta-synthase; Region: cysta_beta; TIGR01137
1104326006259	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1104326006260	dimer interface [polypeptide binding]; other site
1104326006261	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326006262	catalytic residue [active]
1104326006263	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
1104326006264	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1104326006265	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1104326006266	Walker A/P-loop; other site
1104326006267	ATP binding site [chemical binding]; other site
1104326006268	Q-loop/lid; other site
1104326006269	ABC transporter signature motif; other site
1104326006270	Walker B; other site
1104326006271	D-loop; other site
1104326006272	H-loop/switch region; other site
1104326006273	NIL domain; Region: NIL; pfam09383
1104326006274	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326006275	dimer interface [polypeptide binding]; other site
1104326006276	conserved gate region; other site
1104326006277	putative PBP binding loops; other site
1104326006278	ABC-ATPase subunit interface; other site
1104326006279	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1104326006280	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1104326006281	hypothetical protein; Provisional; Region: PRK10292
1104326006282	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326006283	dimer interface [polypeptide binding]; other site
1104326006284	conserved gate region; other site
1104326006285	putative PBP binding loops; other site
1104326006286	ABC-ATPase subunit interface; other site
1104326006287	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326006288	dimer interface [polypeptide binding]; other site
1104326006289	conserved gate region; other site
1104326006290	putative PBP binding loops; other site
1104326006291	ABC-ATPase subunit interface; other site
1104326006292	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1104326006293	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326006294	Walker A/P-loop; other site
1104326006295	ATP binding site [chemical binding]; other site
1104326006296	Q-loop/lid; other site
1104326006297	ABC transporter signature motif; other site
1104326006298	Walker B; other site
1104326006299	D-loop; other site
1104326006300	H-loop/switch region; other site
1104326006301	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326006302	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326006303	substrate binding pocket [chemical binding]; other site
1104326006304	membrane-bound complex binding site; other site
1104326006305	hinge residues; other site
1104326006306	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1104326006307	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326006308	dimer interface [polypeptide binding]; other site
1104326006309	phosphorylation site [posttranslational modification]
1104326006310	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326006311	ATP binding site [chemical binding]; other site
1104326006312	Mg2+ binding site [ion binding]; other site
1104326006313	G-X-G motif; other site
1104326006314	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1104326006315	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326006316	active site
1104326006317	phosphorylation site [posttranslational modification]
1104326006318	intermolecular recognition site; other site
1104326006319	dimerization interface [polypeptide binding]; other site
1104326006320	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326006321	DNA binding residues [nucleotide binding]
1104326006322	dimerization interface [polypeptide binding]; other site
1104326006323	Domain of unknown function (DUF336); Region: DUF336; cl01249
1104326006324	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1104326006325	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1104326006326	active site clefts [active]
1104326006327	zinc binding site [ion binding]; other site
1104326006328	dimer interface [polypeptide binding]; other site
1104326006329	potential protein location (hypothetical protein A3UG_09525 [Enterobacter cloacae subsp. dissolvens SDM]) that overlaps RNA (tRNA-V)
1104326006330	multidrug efflux protein; Reviewed; Region: PRK01766
1104326006331	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1104326006332	cation binding site [ion binding]; other site
1104326006333	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1104326006334	Lumazine binding domain; Region: Lum_binding; pfam00677
1104326006335	Lumazine binding domain; Region: Lum_binding; pfam00677
1104326006336	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1104326006337	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326006338	S-adenosylmethionine binding site [chemical binding]; other site
1104326006339	putative transporter; Provisional; Region: PRK11043
1104326006340	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326006341	putative substrate translocation pore; other site
1104326006342	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1104326006343	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006344	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326006345	dimerization interface [polypeptide binding]; other site
1104326006346	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1104326006347	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326006348	DNA binding site [nucleotide binding]
1104326006349	domain linker motif; other site
1104326006350	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1104326006351	dimerization interface [polypeptide binding]; other site
1104326006352	ligand binding site [chemical binding]; other site
1104326006353	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326006354	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326006355	putative substrate translocation pore; other site
1104326006356	superoxide dismutase; Provisional; Region: PRK10543
1104326006357	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1104326006358	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1104326006359	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1104326006360	NlpC/P60 family; Region: NLPC_P60; pfam00877
1104326006361	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1104326006362	putative GSH binding site [chemical binding]; other site
1104326006363	catalytic residues [active]
1104326006364	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1104326006365	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1104326006366	dimer interface [polypeptide binding]; other site
1104326006367	catalytic site [active]
1104326006368	putative active site [active]
1104326006369	putative substrate binding site [chemical binding]; other site
1104326006370	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326006371	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1104326006372	dimer interface [polypeptide binding]; other site
1104326006373	active site
1104326006374	metal binding site [ion binding]; metal-binding site
1104326006375	glutathione binding site [chemical binding]; other site
1104326006376	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1104326006377	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1104326006378	FMN binding site [chemical binding]; other site
1104326006379	active site
1104326006380	substrate binding site [chemical binding]; other site
1104326006381	catalytic residue [active]
1104326006382	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326006383	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326006384	putative metal dependent hydrolase; Provisional; Region: PRK11598
1104326006385	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1104326006386	Sulfatase; Region: Sulfatase; pfam00884
1104326006387	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1104326006388	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326006389	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326006390	active site
1104326006391	catalytic tetrad [active]
1104326006392	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1104326006393	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1104326006394	E-class dimer interface [polypeptide binding]; other site
1104326006395	P-class dimer interface [polypeptide binding]; other site
1104326006396	active site
1104326006397	Cu2+ binding site [ion binding]; other site
1104326006398	Zn2+ binding site [ion binding]; other site
1104326006399	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1104326006400	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1104326006401	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1104326006402	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326006403	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326006404	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1104326006405	transcriptional regulator SlyA; Provisional; Region: PRK03573
1104326006406	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1104326006407	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326006408	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326006409	metal binding site [ion binding]; metal-binding site
1104326006410	active site
1104326006411	I-site; other site
1104326006412	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1104326006413	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1104326006414	lysozyme inhibitor; Provisional; Region: PRK11372
1104326006415	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1104326006416	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1104326006417	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1104326006418	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1104326006419	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1104326006420	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1104326006421	active site
1104326006422	HIGH motif; other site
1104326006423	dimer interface [polypeptide binding]; other site
1104326006424	KMSKS motif; other site
1104326006425	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326006426	RNA binding surface [nucleotide binding]; other site
1104326006427	pyridoxamine kinase; Validated; Region: PRK05756
1104326006428	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1104326006429	dimer interface [polypeptide binding]; other site
1104326006430	pyridoxal binding site [chemical binding]; other site
1104326006431	ATP binding site [chemical binding]; other site
1104326006432	glutathionine S-transferase; Provisional; Region: PRK10542
1104326006433	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1104326006434	C-terminal domain interface [polypeptide binding]; other site
1104326006435	GSH binding site (G-site) [chemical binding]; other site
1104326006436	dimer interface [polypeptide binding]; other site
1104326006437	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1104326006438	N-terminal domain interface [polypeptide binding]; other site
1104326006439	dimer interface [polypeptide binding]; other site
1104326006440	substrate binding pocket (H-site) [chemical binding]; other site
1104326006441	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1104326006442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326006443	putative substrate translocation pore; other site
1104326006444	POT family; Region: PTR2; pfam00854
1104326006445	endonuclease III; Provisional; Region: PRK10702
1104326006446	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1104326006447	minor groove reading motif; other site
1104326006448	helix-hairpin-helix signature motif; other site
1104326006449	substrate binding pocket [chemical binding]; other site
1104326006450	active site
1104326006451	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1104326006452	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1104326006453	electron transport complex protein RnfG; Validated; Region: PRK01908
1104326006454	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1104326006455	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1104326006456	SLBB domain; Region: SLBB; pfam10531
1104326006457	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1104326006458	electron transport complex protein RnfB; Provisional; Region: PRK05113
1104326006459	Putative Fe-S cluster; Region: FeS; cl17515
1104326006460	4Fe-4S binding domain; Region: Fer4; pfam00037
1104326006461	electron transport complex protein RsxA; Provisional; Region: PRK05151
1104326006462	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1104326006463	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1104326006464	putative oxidoreductase; Provisional; Region: PRK11579
1104326006465	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326006466	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326006467	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1104326006468	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1104326006469	active site
1104326006470	purine riboside binding site [chemical binding]; other site
1104326006471	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1104326006472	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326006473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326006474	homodimer interface [polypeptide binding]; other site
1104326006475	catalytic residue [active]
1104326006476	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1104326006477	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1104326006478	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326006479	active site turn [active]
1104326006480	phosphorylation site [posttranslational modification]
1104326006481	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1104326006482	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326006483	DNA binding site [nucleotide binding]
1104326006484	domain linker motif; other site
1104326006485	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1104326006486	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1104326006487	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1104326006488	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1104326006489	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1104326006490	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1104326006491	fumarate hydratase; Provisional; Region: PRK15389
1104326006492	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1104326006493	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1104326006494	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1104326006495	Class II fumarases; Region: Fumarase_classII; cd01362
1104326006496	active site
1104326006497	tetramer interface [polypeptide binding]; other site
1104326006498	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1104326006499	sensor protein RstB; Provisional; Region: PRK10604
1104326006500	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326006501	dimerization interface [polypeptide binding]; other site
1104326006502	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326006503	dimer interface [polypeptide binding]; other site
1104326006504	phosphorylation site [posttranslational modification]
1104326006505	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326006506	ATP binding site [chemical binding]; other site
1104326006507	Mg2+ binding site [ion binding]; other site
1104326006508	G-X-G motif; other site
1104326006509	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1104326006510	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326006511	active site
1104326006512	phosphorylation site [posttranslational modification]
1104326006513	intermolecular recognition site; other site
1104326006514	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326006515	DNA binding site [nucleotide binding]
1104326006516	GlpM protein; Region: GlpM; pfam06942
1104326006517	dihydromonapterin reductase; Provisional; Region: PRK06483
1104326006518	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326006519	NAD(P) binding site [chemical binding]; other site
1104326006520	active site
1104326006521	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1104326006522	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326006523	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326006524	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326006525	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1104326006526	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1104326006527	ligand binding site [chemical binding]; other site
1104326006528	homodimer interface [polypeptide binding]; other site
1104326006529	NAD(P) binding site [chemical binding]; other site
1104326006530	trimer interface B [polypeptide binding]; other site
1104326006531	trimer interface A [polypeptide binding]; other site
1104326006532	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1104326006533	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1104326006534	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1104326006535	universal stress protein UspE; Provisional; Region: PRK11175
1104326006536	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326006537	Ligand Binding Site [chemical binding]; other site
1104326006538	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326006539	Ligand Binding Site [chemical binding]; other site
1104326006540	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1104326006541	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1104326006542	ligand binding site [chemical binding]; other site
1104326006543	flexible hinge region; other site
1104326006544	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1104326006545	putative switch regulator; other site
1104326006546	non-specific DNA interactions [nucleotide binding]; other site
1104326006547	DNA binding site [nucleotide binding]
1104326006548	sequence specific DNA binding site [nucleotide binding]; other site
1104326006549	putative cAMP binding site [chemical binding]; other site
1104326006550	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1104326006551	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1104326006552	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1104326006553	DNA binding site [nucleotide binding]
1104326006554	active site
1104326006555	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1104326006556	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1104326006557	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1104326006558	amidohydrolase; Region: amidohydrolases; TIGR01891
1104326006559	putative metal binding site [ion binding]; other site
1104326006560	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1104326006561	amidohydrolase; Region: amidohydrolases; TIGR01891
1104326006562	putative metal binding site [ion binding]; other site
1104326006563	dimer interface [polypeptide binding]; other site
1104326006564	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1104326006565	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006566	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1104326006567	putative substrate binding pocket [chemical binding]; other site
1104326006568	putative dimerization interface [polypeptide binding]; other site
1104326006569	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1104326006570	Smr domain; Region: Smr; pfam01713
1104326006571	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1104326006572	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326006573	dimer interface [polypeptide binding]; other site
1104326006574	ligand binding site [chemical binding]; other site
1104326006575	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326006576	dimerization interface [polypeptide binding]; other site
1104326006577	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326006578	dimer interface [polypeptide binding]; other site
1104326006579	putative CheW interface [polypeptide binding]; other site
1104326006580	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326006581	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326006582	active site
1104326006583	catalytic tetrad [active]
1104326006584	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1104326006585	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1104326006586	active site
1104326006587	DNA binding site [nucleotide binding]
1104326006588	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1104326006589	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1104326006590	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1104326006591	Catalytic site [active]
1104326006592	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326006593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006594	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326006595	dimerization interface [polypeptide binding]; other site
1104326006596	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326006597	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
1104326006598	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1104326006599	NAD(P) binding site [chemical binding]; other site
1104326006600	active site
1104326006601	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1104326006602	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326006603	DNA-binding site [nucleotide binding]; DNA binding site
1104326006604	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326006605	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326006606	homodimer interface [polypeptide binding]; other site
1104326006607	catalytic residue [active]
1104326006608	N-acetyltransferase; Region: Acetyltransf_2; pfam00797
1104326006609	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1104326006610	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1104326006611	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326006612	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326006613	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326006614	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326006615	dimer interface [polypeptide binding]; other site
1104326006616	phosphorylation site [posttranslational modification]
1104326006617	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326006618	ATP binding site [chemical binding]; other site
1104326006619	Mg2+ binding site [ion binding]; other site
1104326006620	G-X-G motif; other site
1104326006621	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326006622	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326006623	active site
1104326006624	phosphorylation site [posttranslational modification]
1104326006625	intermolecular recognition site; other site
1104326006626	dimerization interface [polypeptide binding]; other site
1104326006627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326006628	DNA binding site [nucleotide binding]
1104326006629	MltA-interacting protein MipA; Region: MipA; cl01504
1104326006630	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1104326006631	active site
1104326006632	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1104326006633	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1104326006634	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1104326006635	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1104326006636	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1104326006637	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1104326006638	CHASE4 domain; Region: CHASE4; pfam05228
1104326006639	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326006640	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326006641	metal binding site [ion binding]; metal-binding site
1104326006642	active site
1104326006643	I-site; other site
1104326006644	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326006645	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1104326006646	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1104326006647	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1104326006648	active site
1104326006649	Zn binding site [ion binding]; other site
1104326006650	4-aminobutyrate transaminase; Provisional; Region: PRK09792
1104326006651	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326006652	inhibitor-cofactor binding pocket; inhibition site
1104326006653	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326006654	catalytic residue [active]
1104326006655	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1104326006656	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1104326006657	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
1104326006658	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
1104326006659	NAD(P) binding site [chemical binding]; other site
1104326006660	catalytic residues [active]
1104326006661	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1104326006662	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326006663	non-specific DNA binding site [nucleotide binding]; other site
1104326006664	salt bridge; other site
1104326006665	sequence-specific DNA binding site [nucleotide binding]; other site
1104326006666	Cupin domain; Region: Cupin_2; pfam07883
1104326006667	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1104326006668	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1104326006669	catalytic triad [active]
1104326006670	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1104326006671	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1104326006672	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1104326006673	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1104326006674	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326006675	putative substrate translocation pore; other site
1104326006676	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1104326006677	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006678	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1104326006679	dimerization interface [polypeptide binding]; other site
1104326006680	substrate binding pocket [chemical binding]; other site
1104326006681	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1104326006682	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1104326006683	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1104326006684	nucleotide binding site [chemical binding]; other site
1104326006685	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1104326006686	AAA domain; Region: AAA_26; pfam13500
1104326006687	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1104326006688	Cl- selectivity filter; other site
1104326006689	Cl- binding residues [ion binding]; other site
1104326006690	pore gating glutamate residue; other site
1104326006691	dimer interface [polypeptide binding]; other site
1104326006692	S-type Pyocin; Region: Pyocin_S; pfam06958
1104326006693	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1104326006694	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1104326006695	Walker A/P-loop; other site
1104326006696	ATP binding site [chemical binding]; other site
1104326006697	Q-loop/lid; other site
1104326006698	ABC transporter signature motif; other site
1104326006699	Walker B; other site
1104326006700	D-loop; other site
1104326006701	H-loop/switch region; other site
1104326006702	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1104326006703	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326006704	dimer interface [polypeptide binding]; other site
1104326006705	conserved gate region; other site
1104326006706	ABC-ATPase subunit interface; other site
1104326006707	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1104326006708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326006709	dimer interface [polypeptide binding]; other site
1104326006710	conserved gate region; other site
1104326006711	putative PBP binding loops; other site
1104326006712	ABC-ATPase subunit interface; other site
1104326006713	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1104326006714	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1104326006715	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1104326006716	putative C-terminal domain interface [polypeptide binding]; other site
1104326006717	putative GSH binding site (G-site) [chemical binding]; other site
1104326006718	putative dimer interface [polypeptide binding]; other site
1104326006719	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1104326006720	putative N-terminal domain interface [polypeptide binding]; other site
1104326006721	putative dimer interface [polypeptide binding]; other site
1104326006722	putative substrate binding pocket (H-site) [chemical binding]; other site
1104326006723	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1104326006724	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1104326006725	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
1104326006726	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1104326006727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1104326006728	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1104326006729	nitrate transport ATP-binding subunits C and D; Region: ntrCD; TIGR01184
1104326006730	Walker A/P-loop; other site
1104326006731	ATP binding site [chemical binding]; other site
1104326006732	Q-loop/lid; other site
1104326006733	ABC transporter signature motif; other site
1104326006734	Walker B; other site
1104326006735	D-loop; other site
1104326006736	H-loop/switch region; other site
1104326006737	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1104326006738	urea carboxylase-associated protein 2; Region: urea_degr_2; TIGR03425
1104326006739	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1104326006740	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1104326006741	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1104326006742	urea carboxylase; Region: urea_carbox; TIGR02712
1104326006743	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1104326006744	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
1104326006745	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1104326006746	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1104326006747	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1104326006748	carboxyltransferase (CT) interaction site; other site
1104326006749	biotinylation site [posttranslational modification]; other site
1104326006750	allophanate hydrolase; Provisional; Region: PRK08186
1104326006751	Amidase; Region: Amidase; cl11426
1104326006752	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1104326006753	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1104326006754	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1104326006755	4Fe-4S binding domain; Region: Fer4; pfam00037
1104326006756	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1104326006757	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1104326006758	putative [Fe4-S4] binding site [ion binding]; other site
1104326006759	putative molybdopterin cofactor binding site [chemical binding]; other site
1104326006760	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1104326006761	putative molybdopterin cofactor binding site; other site
1104326006762	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1104326006763	lipoprotein; Reviewed; Region: PRK02939
1104326006764	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1104326006765	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326006766	Coenzyme A binding pocket [chemical binding]; other site
1104326006767	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1104326006768	hypothetical protein; Provisional; Region: PRK13659
1104326006769	hypothetical protein; Provisional; Region: PRK02237
1104326006770	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1104326006771	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1104326006772	putative active site pocket [active]
1104326006773	putative metal binding site [ion binding]; other site
1104326006774	putative oxidoreductase; Provisional; Region: PRK10083
1104326006775	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1104326006776	putative NAD(P) binding site [chemical binding]; other site
1104326006777	catalytic Zn binding site [ion binding]; other site
1104326006778	structural Zn binding site [ion binding]; other site
1104326006779	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326006780	metabolite-proton symporter; Region: 2A0106; TIGR00883
1104326006781	putative substrate translocation pore; other site
1104326006782	Glucuronate isomerase; Region: UxaC; pfam02614
1104326006783	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1104326006784	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1104326006785	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326006786	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1104326006787	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1104326006788	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1104326006789	YdfZ protein; Region: YdfZ; pfam14001
1104326006790	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326006791	Ligand Binding Site [chemical binding]; other site
1104326006792	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1104326006793	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326006794	DNA-binding site [nucleotide binding]; DNA binding site
1104326006795	FCD domain; Region: FCD; pfam07729
1104326006796	malonic semialdehyde reductase; Provisional; Region: PRK10538
1104326006797	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1104326006798	putative NAD(P) binding site [chemical binding]; other site
1104326006799	homodimer interface [polypeptide binding]; other site
1104326006800	homotetramer interface [polypeptide binding]; other site
1104326006801	active site
1104326006802	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1104326006803	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1104326006804	active site
1104326006805	Zn binding site [ion binding]; other site
1104326006806	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1104326006807	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1104326006808	CHASE4 domain; Region: CHASE4; pfam05228
1104326006809	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326006810	putative active site [active]
1104326006811	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326006812	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326006813	metal binding site [ion binding]; metal-binding site
1104326006814	active site
1104326006815	I-site; other site
1104326006816	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326006817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326006818	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1104326006819	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1104326006820	putative ligand binding site [chemical binding]; other site
1104326006821	putative NAD binding site [chemical binding]; other site
1104326006822	catalytic site [active]
1104326006823	hypothetical protein; Provisional; Region: PRK10695
1104326006824	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1104326006825	Protein of unknown function (DUF1318); Region: DUF1318; pfam07027
1104326006826	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
1104326006827	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326006828	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1104326006829	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1104326006830	NAD(P) binding site [chemical binding]; other site
1104326006831	catalytic residues [active]
1104326006832	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326006833	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326006834	metal binding site [ion binding]; metal-binding site
1104326006835	active site
1104326006836	I-site; other site
1104326006837	tyramine oxidase; Provisional; Region: tynA; PRK14696
1104326006838	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1104326006839	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
1104326006840	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
1104326006841	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
1104326006842	Protein of unknown function (DUF796); Region: DUF796; cl01226
1104326006843	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1104326006844	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1104326006845	substrate binding site [chemical binding]; other site
1104326006846	dimer interface [polypeptide binding]; other site
1104326006847	NADP binding site [chemical binding]; other site
1104326006848	catalytic residues [active]
1104326006849	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
1104326006850	substrate binding site [chemical binding]; other site
1104326006851	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1104326006852	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1104326006853	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1104326006854	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
1104326006855	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1104326006856	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1104326006857	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1104326006858	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1104326006859	FAD binding pocket [chemical binding]; other site
1104326006860	FAD binding motif [chemical binding]; other site
1104326006861	phosphate binding motif [ion binding]; other site
1104326006862	beta-alpha-beta structure motif; other site
1104326006863	NAD(p) ribose binding residues [chemical binding]; other site
1104326006864	NAD binding pocket [chemical binding]; other site
1104326006865	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1104326006866	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326006867	catalytic loop [active]
1104326006868	iron binding site [ion binding]; other site
1104326006869	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1104326006870	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1104326006871	substrate binding site [chemical binding]; other site
1104326006872	oxyanion hole (OAH) forming residues; other site
1104326006873	trimer interface [polypeptide binding]; other site
1104326006874	enoyl-CoA hydratase; Provisional; Region: PRK08140
1104326006875	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1104326006876	substrate binding site [chemical binding]; other site
1104326006877	oxyanion hole (OAH) forming residues; other site
1104326006878	trimer interface [polypeptide binding]; other site
1104326006879	3-hydroxy-acyl-CoA dehydrogenase; Validated; Region: PRK08268
1104326006880	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1104326006881	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1104326006882	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1104326006883	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1104326006884	CoenzymeA binding site [chemical binding]; other site
1104326006885	subunit interaction site [polypeptide binding]; other site
1104326006886	PHB binding site; other site
1104326006887	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1104326006888	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1104326006889	dimer interface [polypeptide binding]; other site
1104326006890	active site
1104326006891	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
1104326006892	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1104326006893	active site
1104326006894	AMP binding site [chemical binding]; other site
1104326006895	homodimer interface [polypeptide binding]; other site
1104326006896	acyl-activating enzyme (AAE) consensus motif; other site
1104326006897	CoA binding site [chemical binding]; other site
1104326006898	PaaX-like protein; Region: PaaX; pfam07848
1104326006899	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
1104326006900	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1104326006901	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
1104326006902	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1104326006903	putative trimer interface [polypeptide binding]; other site
1104326006904	putative metal binding site [ion binding]; other site
1104326006905	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1104326006906	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1104326006907	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1104326006908	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1104326006909	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1104326006910	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1104326006911	hypothetical protein; Provisional; Region: PRK08204
1104326006912	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1104326006913	active site
1104326006914	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326006915	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006916	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1104326006917	putative effector binding pocket; other site
1104326006918	putative dimerization interface [polypeptide binding]; other site
1104326006919	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326006920	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326006921	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
1104326006922	CGNR zinc finger; Region: zf-CGNR; pfam11706
1104326006923	MltA-interacting protein MipA; Region: MipA; cl01504
1104326006924	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1104326006925	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326006926	active site
1104326006927	phosphorylation site [posttranslational modification]
1104326006928	intermolecular recognition site; other site
1104326006929	dimerization interface [polypeptide binding]; other site
1104326006930	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326006931	DNA binding site [nucleotide binding]
1104326006932	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326006933	HAMP domain; Region: HAMP; pfam00672
1104326006934	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326006935	dimer interface [polypeptide binding]; other site
1104326006936	phosphorylation site [posttranslational modification]
1104326006937	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326006938	ATP binding site [chemical binding]; other site
1104326006939	Mg2+ binding site [ion binding]; other site
1104326006940	G-X-G motif; other site
1104326006941	Predicted transcriptional regulator [Transcription]; Region: COG1959
1104326006942	Transcriptional regulator; Region: Rrf2; pfam02082
1104326006943	Transcriptional regulator; Region: Rrf2; cl17282
1104326006944	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1104326006945	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1104326006946	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326006947	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326006948	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1104326006949	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326006950	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1104326006951	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326006952	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1104326006953	short chain dehydrogenase; Provisional; Region: PRK12744
1104326006954	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326006955	NAD(P) binding site [chemical binding]; other site
1104326006956	active site
1104326006957	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326006958	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006959	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1104326006960	putative effector binding pocket; other site
1104326006961	putative dimerization interface [polypeptide binding]; other site
1104326006962	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1104326006963	homotrimer interaction site [polypeptide binding]; other site
1104326006964	putative active site [active]
1104326006965	YebG protein; Region: YebG; pfam07130
1104326006966	NIPSNAP; Region: NIPSNAP; pfam07978
1104326006967	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1104326006968	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
1104326006969	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1104326006970	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1104326006971	classical (c) SDRs; Region: SDR_c; cd05233
1104326006972	NAD(P) binding site [chemical binding]; other site
1104326006973	active site
1104326006974	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1104326006975	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326006976	outer membrane protease; Reviewed; Region: PRK10993
1104326006977	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326006978	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
1104326006979	catalytic triad [active]
1104326006980	conserved cis-peptide bond; other site
1104326006981	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1104326006982	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1104326006983	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326006984	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326006985	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326006986	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326006987	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326006988	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326006989	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326006990	putative effector binding pocket; other site
1104326006991	dimerization interface [polypeptide binding]; other site
1104326006992	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1104326006993	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1104326006994	FMN binding site [chemical binding]; other site
1104326006995	active site
1104326006996	substrate binding site [chemical binding]; other site
1104326006997	catalytic residue [active]
1104326006998	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
1104326006999	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558
1104326007000	SnoaL-like domain; Region: SnoaL_2; pfam12680
1104326007001	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326007002	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326007003	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1104326007004	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1104326007005	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326007006	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326007007	SM domain found in Ataxin-2; Region: SM-ATX; pfam14438
1104326007008	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1104326007009	SnoaL-like domain; Region: SnoaL_2; pfam12680
1104326007010	short chain dehydrogenase; Provisional; Region: PRK06101
1104326007011	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326007012	NAD(P) binding site [chemical binding]; other site
1104326007013	active site
1104326007014	Predicted NAD/FAD-binding protein [General function prediction only]; Region: COG2907
1104326007015	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1104326007016	Protein of unknown function (DUF1365); Region: DUF1365; pfam07103
1104326007017	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1104326007018	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326007019	S-adenosylmethionine binding site [chemical binding]; other site
1104326007020	Protein of unknown function (DUF2878); Region: DUF2878; pfam11086
1104326007021	Protein of unknown function (DUF3833); Region: DUF3833; pfam12915
1104326007022	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1104326007023	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1104326007024	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007025	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007026	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326007027	putative effector binding pocket; other site
1104326007028	dimerization interface [polypeptide binding]; other site
1104326007029	methionine synthase; Provisional; Region: PRK01207
1104326007030	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1104326007031	substrate binding site [chemical binding]; other site
1104326007032	THF binding site; other site
1104326007033	zinc-binding site [ion binding]; other site
1104326007034	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
1104326007035	Protein of unknown function (DUF796); Region: DUF796; cl01226
1104326007036	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
1104326007037	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1104326007038	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1104326007039	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1104326007040	active site
1104326007041	azoreductase; Reviewed; Region: PRK00170
1104326007042	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1104326007043	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1104326007044	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326007045	ATP binding site [chemical binding]; other site
1104326007046	putative Mg++ binding site [ion binding]; other site
1104326007047	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326007048	nucleotide binding region [chemical binding]; other site
1104326007049	ATP-binding site [chemical binding]; other site
1104326007050	Helicase associated domain (HA2); Region: HA2; pfam04408
1104326007051	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1104326007052	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1104326007053	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1104326007054	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1104326007055	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1104326007056	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1104326007057	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326007058	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326007059	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007060	putative substrate translocation pore; other site
1104326007061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007062	metabolite-proton symporter; Region: 2A0106; TIGR00883
1104326007063	putative substrate translocation pore; other site
1104326007064	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1104326007065	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1104326007066	putative active site [active]
1104326007067	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1104326007068	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1104326007069	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1104326007070	cytochrome b561; Provisional; Region: PRK11513
1104326007071	putative oxidoreductase; Provisional; Region: PRK11579
1104326007072	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326007073	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326007074	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1104326007075	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1104326007076	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326007077	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1104326007078	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007079	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007080	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007081	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007082	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007083	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007084	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007085	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007086	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007087	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007088	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007089	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007090	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007091	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007092	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007093	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007094	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007095	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007096	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007097	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007098	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007099	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007100	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007101	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007102	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007103	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007104	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007105	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007106	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007107	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007108	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007109	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007110	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007111	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1104326007112	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326007113	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1104326007114	Family description; Region: VCBS; pfam13517
1104326007115	Family description; Region: VCBS; pfam13517
1104326007116	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1104326007117	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1104326007118	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326007119	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326007120	Walker A/P-loop; other site
1104326007121	ATP binding site [chemical binding]; other site
1104326007122	Q-loop/lid; other site
1104326007123	ABC transporter signature motif; other site
1104326007124	Walker B; other site
1104326007125	D-loop; other site
1104326007126	H-loop/switch region; other site
1104326007127	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1104326007128	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326007129	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326007130	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326007131	DNA binding residues [nucleotide binding]
1104326007132	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326007133	CsbD-like; Region: CsbD; pfam05532
1104326007134	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1104326007135	putative acetyltransferase; Provisional; Region: PRK03624
1104326007136	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326007137	Coenzyme A binding pocket [chemical binding]; other site
1104326007138	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1104326007139	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007140	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326007141	dimerization interface [polypeptide binding]; other site
1104326007142	anti-adapter protein IraM; Provisional; Region: PRK09919
1104326007143	Phage minor tail protein; Region: Phage_min_tail; cl01940
1104326007144	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1104326007145	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1104326007146	Catalytic site [active]
1104326007147	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1104326007148	putative metal binding site [ion binding]; other site
1104326007149	putative homodimer interface [polypeptide binding]; other site
1104326007150	putative homotetramer interface [polypeptide binding]; other site
1104326007151	putative homodimer-homodimer interface [polypeptide binding]; other site
1104326007152	putative allosteric switch controlling residues; other site
1104326007153	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1104326007154	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1104326007155	substrate binding site [chemical binding]; other site
1104326007156	catalytic Zn binding site [ion binding]; other site
1104326007157	NAD binding site [chemical binding]; other site
1104326007158	structural Zn binding site [ion binding]; other site
1104326007159	dimer interface [polypeptide binding]; other site
1104326007160	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1104326007161	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326007162	dimer interface [polypeptide binding]; other site
1104326007163	ligand binding site [chemical binding]; other site
1104326007164	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326007165	dimerization interface [polypeptide binding]; other site
1104326007166	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326007167	dimer interface [polypeptide binding]; other site
1104326007168	putative CheW interface [polypeptide binding]; other site
1104326007169	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1104326007170	Increased loss of mitochondrial DNA protein 1; Region: Ilm1; pfam10311
1104326007171	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1104326007172	Trp docking motif [polypeptide binding]; other site
1104326007173	putative active site [active]
1104326007174	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1104326007175	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007176	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326007177	dimerization interface [polypeptide binding]; other site
1104326007178	short chain dehydrogenase; Provisional; Region: PRK06701
1104326007179	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1104326007180	NAD binding site [chemical binding]; other site
1104326007181	metal binding site [ion binding]; metal-binding site
1104326007182	active site
1104326007183	hypothetical protein; Provisional; Region: PRK10053
1104326007184	Predicted membrane protein [Function unknown]; Region: COG2323
1104326007185	hypothetical protein; Validated; Region: PRK03657
1104326007186	short chain dehydrogenase; Provisional; Region: PRK07109
1104326007187	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326007188	NAD(P) binding site [chemical binding]; other site
1104326007189	active site
1104326007190	trehalose synthase; Region: treS_nterm; TIGR02456
1104326007191	Alpha amylase catalytic domain found in Trehalose synthetase; Region: AmyAc_TreS; cd11334
1104326007192	active site
1104326007193	catalytic site [active]
1104326007194	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1104326007195	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1104326007196	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1104326007197	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1104326007198	dimanganese center [ion binding]; other site
1104326007199	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1104326007200	dinuclear metal binding motif [ion binding]; other site
1104326007201	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1104326007202	dinuclear metal binding motif [ion binding]; other site
1104326007203	General stress protein [General function prediction only]; Region: GsiB; COG3729
1104326007204	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1104326007205	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1104326007206	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1104326007207	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1104326007208	substrate binding pocket [chemical binding]; other site
1104326007209	catalytic triad [active]
1104326007210	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1104326007211	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007212	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326007213	dimerization interface [polypeptide binding]; other site
1104326007214	putative aminotransferase; Provisional; Region: PRK12414
1104326007215	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326007216	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326007217	homodimer interface [polypeptide binding]; other site
1104326007218	catalytic residue [active]
1104326007219	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
1104326007220	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326007221	substrate binding pocket [chemical binding]; other site
1104326007222	membrane-bound complex binding site; other site
1104326007223	hinge residues; other site
1104326007224	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1104326007225	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1104326007226	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1104326007227	putative trimer interface [polypeptide binding]; other site
1104326007228	putative CoA binding site [chemical binding]; other site
1104326007229	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1104326007230	putative trimer interface [polypeptide binding]; other site
1104326007231	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1104326007232	putative trimer interface [polypeptide binding]; other site
1104326007233	putative CoA binding site [chemical binding]; other site
1104326007234	putative CoA binding site [chemical binding]; other site
1104326007235	tellurite resistance protein TehB; Provisional; Region: PRK11207
1104326007236	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326007237	S-adenosylmethionine binding site [chemical binding]; other site
1104326007238	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1104326007239	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1104326007240	metal binding site [ion binding]; metal-binding site
1104326007241	dimer interface [polypeptide binding]; other site
1104326007242	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326007243	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1104326007244	peptide binding site [polypeptide binding]; other site
1104326007245	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1104326007246	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1104326007247	EamA-like transporter family; Region: EamA; pfam00892
1104326007248	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326007249	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007250	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1104326007251	benzoate transporter; Region: benE; TIGR00843
1104326007252	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1104326007253	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326007254	non-specific DNA binding site [nucleotide binding]; other site
1104326007255	salt bridge; other site
1104326007256	sequence-specific DNA binding site [nucleotide binding]; other site
1104326007257	Cupin domain; Region: Cupin_2; pfam07883
1104326007258	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1104326007259	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1104326007260	Peptidase family U32; Region: Peptidase_U32; pfam01136
1104326007261	Collagenase; Region: DUF3656; pfam12392
1104326007262	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1104326007263	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1104326007264	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1104326007265	conserved cys residue [active]
1104326007266	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007267	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007268	Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521
1104326007269	active site residue [active]
1104326007270	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1104326007271	substrate binding site [chemical binding]; other site
1104326007272	THF binding site; other site
1104326007273	zinc-binding site [ion binding]; other site
1104326007274	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1104326007275	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
1104326007276	putative ligand binding site [chemical binding]; other site
1104326007277	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1104326007278	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326007279	TM-ABC transporter signature motif; other site
1104326007280	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1104326007281	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1104326007282	TM-ABC transporter signature motif; other site
1104326007283	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
1104326007284	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1104326007285	Walker A/P-loop; other site
1104326007286	ATP binding site [chemical binding]; other site
1104326007287	Q-loop/lid; other site
1104326007288	ABC transporter signature motif; other site
1104326007289	Walker B; other site
1104326007290	D-loop; other site
1104326007291	H-loop/switch region; other site
1104326007292	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1104326007293	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1104326007294	Walker A/P-loop; other site
1104326007295	ATP binding site [chemical binding]; other site
1104326007296	Q-loop/lid; other site
1104326007297	ABC transporter signature motif; other site
1104326007298	Walker B; other site
1104326007299	D-loop; other site
1104326007300	H-loop/switch region; other site
1104326007301	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1104326007302	putative transporter; Provisional; Region: PRK10054
1104326007303	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007304	putative substrate translocation pore; other site
1104326007305	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1104326007306	EamA-like transporter family; Region: EamA; pfam00892
1104326007307	EamA-like transporter family; Region: EamA; pfam00892
1104326007308	hypothetical protein; Provisional; Region: PRK10106
1104326007309	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1104326007310	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007311	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007312	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1104326007313	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326007314	inner membrane protein; Provisional; Region: PRK10995
1104326007315	putative arabinose transporter; Provisional; Region: PRK03545
1104326007316	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007317	putative substrate translocation pore; other site
1104326007318	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1104326007319	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1104326007320	short chain dehydrogenase; Provisional; Region: PRK07577
1104326007321	classical (c) SDRs; Region: SDR_c; cd05233
1104326007322	NAD(P) binding site [chemical binding]; other site
1104326007323	active site
1104326007324	Domain of unknown function (DUF386); Region: DUF386; cl01047
1104326007325	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1104326007326	BNR repeat-like domain; Region: BNR_2; pfam13088
1104326007327	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1104326007328	putative transporter; Provisional; Region: PRK10484
1104326007329	Na binding site [ion binding]; other site
1104326007330	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1104326007331	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1104326007332	inhibitor site; inhibition site
1104326007333	active site
1104326007334	dimer interface [polypeptide binding]; other site
1104326007335	catalytic residue [active]
1104326007336	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1104326007337	5-hydroxyvalerate dehydrogenase (HVD) catalyzes the oxidation of 5-hydroxyvalerate to 5-oxovalerate with NAD+ as cofactor; Region: HVD; cd08193
1104326007338	putative active site [active]
1104326007339	metal binding site [ion binding]; metal-binding site
1104326007340	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1104326007341	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1104326007342	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1104326007343	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1104326007344	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1104326007345	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326007346	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1104326007347	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1104326007348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007349	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1104326007350	putative dimerization interface [polypeptide binding]; other site
1104326007351	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1104326007352	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1104326007353	NAD(P) binding site [chemical binding]; other site
1104326007354	catalytic residues [active]
1104326007355	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326007356	dimer interface [polypeptide binding]; other site
1104326007357	ligand binding site [chemical binding]; other site
1104326007358	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326007359	dimerization interface [polypeptide binding]; other site
1104326007360	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1104326007361	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326007362	dimer interface [polypeptide binding]; other site
1104326007363	putative CheW interface [polypeptide binding]; other site
1104326007364	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1104326007365	glutaminase; Provisional; Region: PRK00971
1104326007366	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1104326007367	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326007368	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326007369	metal binding site [ion binding]; metal-binding site
1104326007370	active site
1104326007371	I-site; other site
1104326007372	MASE2 domain; Region: MASE2; pfam05230
1104326007373	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326007374	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326007375	metal binding site [ion binding]; metal-binding site
1104326007376	active site
1104326007377	I-site; other site
1104326007378	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1104326007379	GAF domain; Region: GAF; pfam01590
1104326007380	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326007381	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326007382	metal binding site [ion binding]; metal-binding site
1104326007383	active site
1104326007384	I-site; other site
1104326007385	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326007386	Coenzyme A binding pocket [chemical binding]; other site
1104326007387	altronate oxidoreductase; Provisional; Region: PRK03643
1104326007388	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1104326007389	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1104326007390	Predicted membrane protein [Function unknown]; Region: COG3781
1104326007391	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1104326007392	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1104326007393	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326007394	Coenzyme A binding pocket [chemical binding]; other site
1104326007395	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1104326007396	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326007397	Coenzyme A binding pocket [chemical binding]; other site
1104326007398	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1104326007399	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326007400	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1104326007401	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326007402	active site
1104326007403	phosphorylation site [posttranslational modification]
1104326007404	intermolecular recognition site; other site
1104326007405	dimerization interface [polypeptide binding]; other site
1104326007406	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326007407	DNA binding site [nucleotide binding]
1104326007408	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326007409	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1104326007410	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326007411	dimer interface [polypeptide binding]; other site
1104326007412	phosphorylation site [posttranslational modification]
1104326007413	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326007414	ATP binding site [chemical binding]; other site
1104326007415	Mg2+ binding site [ion binding]; other site
1104326007416	G-X-G motif; other site
1104326007417	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1104326007418	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1104326007419	TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; Region: TlpA_like_DipZ_like; cd03012
1104326007420	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1104326007421	catalytic residues [active]
1104326007422	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
1104326007423	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326007424	S-adenosylmethionine binding site [chemical binding]; other site
1104326007425	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1104326007426	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1104326007427	dimer interface [polypeptide binding]; other site
1104326007428	ADP-ribose binding site [chemical binding]; other site
1104326007429	active site
1104326007430	nudix motif; other site
1104326007431	metal binding site [ion binding]; metal-binding site
1104326007432	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1104326007433	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1104326007434	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326007435	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
1104326007436	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1104326007437	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1104326007438	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1104326007439	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326007440	Predicted membrane protein [Function unknown]; Region: COG4125
1104326007441	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1104326007442	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1104326007443	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
1104326007444	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
1104326007445	Chromate transporter; Region: Chromate_transp; pfam02417
1104326007446	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1104326007447	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326007448	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326007449	active site
1104326007450	catalytic tetrad [active]
1104326007451	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326007452	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326007453	active site
1104326007454	catalytic tetrad [active]
1104326007455	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326007456	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326007457	active site
1104326007458	catalytic tetrad [active]
1104326007459	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007460	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007461	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1104326007462	putative effector binding pocket; other site
1104326007463	putative dimerization interface [polypeptide binding]; other site
1104326007464	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007465	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007466	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326007467	dimerization interface [polypeptide binding]; other site
1104326007468	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1104326007469	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1104326007470	potential catalytic triad [active]
1104326007471	conserved cys residue [active]
1104326007472	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326007473	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326007474	active site
1104326007475	catalytic tetrad [active]
1104326007476	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG2159
1104326007477	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
1104326007478	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1104326007479	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1104326007480	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1104326007481	Uncharacterized protein conserved in bacteria (DUF2255); Region: DUF2255; pfam10012
1104326007482	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1104326007483	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1104326007484	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326007485	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007486	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007487	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1104326007488	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
1104326007489	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326007490	Copper binding periplasmic protein CusF; Region: CusF_Ec; cl02363
1104326007491	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1104326007492	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
1104326007493	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326007494	active site
1104326007495	phosphorylation site [posttranslational modification]
1104326007496	intermolecular recognition site; other site
1104326007497	dimerization interface [polypeptide binding]; other site
1104326007498	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326007499	DNA binding site [nucleotide binding]
1104326007500	sensor kinase CusS; Provisional; Region: PRK09835
1104326007501	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326007502	dimerization interface [polypeptide binding]; other site
1104326007503	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326007504	dimer interface [polypeptide binding]; other site
1104326007505	phosphorylation site [posttranslational modification]
1104326007506	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326007507	ATP binding site [chemical binding]; other site
1104326007508	Mg2+ binding site [ion binding]; other site
1104326007509	G-X-G motif; other site
1104326007510	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007511	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007512	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
1104326007513	putative substrate binding pocket [chemical binding]; other site
1104326007514	putative dimerization interface [polypeptide binding]; other site
1104326007515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007516	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326007517	putative substrate translocation pore; other site
1104326007518	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
1104326007519	Predicted membrane protein [Function unknown]; Region: COG3817
1104326007520	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1104326007521	Protein of unknown function (DUF969); Region: DUF969; pfam06149
1104326007522	MarR family; Region: MarR_2; cl17246
1104326007523	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1104326007524	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1104326007525	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1104326007526	active site
1104326007527	catalytic site [active]
1104326007528	malto-oligosyltrehalose synthase; Region: trehalose_TreY; TIGR02401
1104326007529	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1104326007530	active site
1104326007531	catalytic site [active]
1104326007532	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1104326007533	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1104326007534	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1104326007535	catalytic site [active]
1104326007536	active site
1104326007537	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1104326007538	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
1104326007539	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1104326007540	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007541	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007542	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1104326007543	substrate binding pocket [chemical binding]; other site
1104326007544	dimerization interface [polypeptide binding]; other site
1104326007545	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007546	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1104326007547	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1104326007548	dimerization interface [polypeptide binding]; other site
1104326007549	substrate binding pocket [chemical binding]; other site
1104326007550	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
1104326007551	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1104326007552	potential frameshift: common BLAST hit: gi|365970532|ref|YP_004952093.1| lipoprotein YddW
1104326007553	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1104326007554	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1104326007555	dimerization domain [polypeptide binding]; other site
1104326007556	dimer interface [polypeptide binding]; other site
1104326007557	catalytic residues [active]
1104326007558	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1104326007559	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1104326007560	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1104326007561	catalytic residues [active]
1104326007562	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
1104326007563	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1104326007564	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1104326007565	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1104326007566	DsbD alpha interface [polypeptide binding]; other site
1104326007567	catalytic residues [active]
1104326007568	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1104326007569	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326007570	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326007571	DNA binding residues [nucleotide binding]
1104326007572	RIB43A; Region: RIB43A; pfam05914
1104326007573	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326007574	dimer interface [polypeptide binding]; other site
1104326007575	ligand binding site [chemical binding]; other site
1104326007576	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326007577	dimerization interface [polypeptide binding]; other site
1104326007578	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326007579	dimer interface [polypeptide binding]; other site
1104326007580	putative CheW interface [polypeptide binding]; other site
1104326007581	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
1104326007582	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326007583	DNA binding site [nucleotide binding]
1104326007584	domain linker motif; other site
1104326007585	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1104326007586	dimerization interface [polypeptide binding]; other site
1104326007587	ligand binding site [chemical binding]; other site
1104326007588	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1104326007589	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1104326007590	substrate binding [chemical binding]; other site
1104326007591	active site
1104326007592	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1104326007593	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1104326007594	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326007595	active site turn [active]
1104326007596	phosphorylation site [posttranslational modification]
1104326007597	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326007598	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1104326007599	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1104326007600	trimer interface; other site
1104326007601	sugar binding site [chemical binding]; other site
1104326007602	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326007603	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1104326007604	putative substrate binding site [chemical binding]; other site
1104326007605	putative ATP binding site [chemical binding]; other site
1104326007606	Sensors of blue-light using FAD; Region: BLUF; pfam04940
1104326007607	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326007608	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1104326007609	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1104326007610	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326007611	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326007612	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1104326007613	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
1104326007614	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326007615	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1104326007616	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1104326007617	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007618	dimer interface [polypeptide binding]; other site
1104326007619	conserved gate region; other site
1104326007620	putative PBP binding loops; other site
1104326007621	ABC-ATPase subunit interface; other site
1104326007622	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
1104326007623	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007624	dimer interface [polypeptide binding]; other site
1104326007625	conserved gate region; other site
1104326007626	putative PBP binding loops; other site
1104326007627	ABC-ATPase subunit interface; other site
1104326007628	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1104326007629	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326007630	Walker A/P-loop; other site
1104326007631	ATP binding site [chemical binding]; other site
1104326007632	Q-loop/lid; other site
1104326007633	ABC transporter signature motif; other site
1104326007634	Walker B; other site
1104326007635	D-loop; other site
1104326007636	H-loop/switch region; other site
1104326007637	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326007638	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1104326007639	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326007640	Walker A/P-loop; other site
1104326007641	ATP binding site [chemical binding]; other site
1104326007642	Q-loop/lid; other site
1104326007643	ABC transporter signature motif; other site
1104326007644	Walker B; other site
1104326007645	D-loop; other site
1104326007646	H-loop/switch region; other site
1104326007647	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326007648	short chain dehydrogenase; Provisional; Region: PRK06500
1104326007649	classical (c) SDRs; Region: SDR_c; cd05233
1104326007650	NAD(P) binding site [chemical binding]; other site
1104326007651	active site
1104326007652	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007653	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007654	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1104326007655	putative effector binding pocket; other site
1104326007656	putative dimerization interface [polypeptide binding]; other site
1104326007657	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1104326007658	transcriptional regulator; Provisional; Region: PRK10632
1104326007659	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007660	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326007661	putative effector binding pocket; other site
1104326007662	dimerization interface [polypeptide binding]; other site
1104326007663	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1104326007664	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
1104326007665	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1104326007666	malate dehydrogenase; Provisional; Region: PRK13529
1104326007667	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1104326007668	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1104326007669	NAD(P) binding site [chemical binding]; other site
1104326007670	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1104326007671	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326007672	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326007673	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1104326007674	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1104326007675	NAD binding site [chemical binding]; other site
1104326007676	substrate binding site [chemical binding]; other site
1104326007677	catalytic Zn binding site [ion binding]; other site
1104326007678	tetramer interface [polypeptide binding]; other site
1104326007679	structural Zn binding site [ion binding]; other site
1104326007680	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326007681	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
1104326007682	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1104326007683	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007684	dimer interface [polypeptide binding]; other site
1104326007685	conserved gate region; other site
1104326007686	putative PBP binding loops; other site
1104326007687	ABC-ATPase subunit interface; other site
1104326007688	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1104326007689	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007690	dimer interface [polypeptide binding]; other site
1104326007691	ABC-ATPase subunit interface; other site
1104326007692	putative PBP binding loops; other site
1104326007693	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1104326007694	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326007695	Walker A/P-loop; other site
1104326007696	ATP binding site [chemical binding]; other site
1104326007697	Q-loop/lid; other site
1104326007698	ABC transporter signature motif; other site
1104326007699	Walker B; other site
1104326007700	D-loop; other site
1104326007701	H-loop/switch region; other site
1104326007702	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326007703	Walker A/P-loop; other site
1104326007704	ATP binding site [chemical binding]; other site
1104326007705	Q-loop/lid; other site
1104326007706	ABC transporter signature motif; other site
1104326007707	Walker B; other site
1104326007708	D-loop; other site
1104326007709	H-loop/switch region; other site
1104326007710	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326007711	putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family; Region: LLM_KPN_01858; TIGR04027
1104326007712	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1104326007713	CMD domain protein, Avi_7170 family; Region: CMD_Avi_7170; TIGR04029
1104326007714	alkylhydroperoxidase domain protein, Avi_7169 family; Region: perox_Avi_7169; TIGR04030
1104326007715	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
1104326007716	MFS transport protein AraJ; Provisional; Region: PRK10091
1104326007717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007718	putative substrate translocation pore; other site
1104326007719	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
1104326007720	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1104326007721	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1104326007722	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1104326007723	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1104326007724	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007725	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007726	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1104326007727	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1104326007728	molybdopterin cofactor binding site; other site
1104326007729	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007730	aromatic amino acid exporter; Provisional; Region: PRK11689
1104326007731	EamA-like transporter family; Region: EamA; cl17759
1104326007732	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326007733	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1104326007734	trimer interface [polypeptide binding]; other site
1104326007735	eyelet of channel; other site
1104326007736	RibD C-terminal domain; Region: RibD_C; cl17279
1104326007737	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1104326007738	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1104326007739	TetR family transcriptional regulator; Provisional; Region: PRK14996
1104326007740	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326007741	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1104326007742	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1104326007743	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1104326007744	[4Fe-4S] binding site [ion binding]; other site
1104326007745	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007746	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007747	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007748	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326007749	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1104326007750	molybdopterin cofactor binding site; other site
1104326007751	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1104326007752	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1104326007753	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1104326007754	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1104326007755	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1104326007756	transmembrane helices; other site
1104326007757	potential frameshift: common BLAST hit: gi|375260112|ref|YP_005019282.1| bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
1104326007758	Serine hydrolase; Region: Ser_hydrolase; pfam06821
1104326007759	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326007760	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1104326007761	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
1104326007762	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1104326007763	Coenzyme A transferase; Region: CoA_trans; cl17247
1104326007764	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1104326007765	citrate lyase subunit gamma; Provisional; Region: PRK13253
1104326007766	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1104326007767	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1104326007768	active site
1104326007769	nucleotide binding site [chemical binding]; other site
1104326007770	HIGH motif; other site
1104326007771	KMSKS motif; other site
1104326007772	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1104326007773	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1104326007774	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326007775	putative substrate translocation pore; other site
1104326007776	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326007777	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
1104326007778	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326007779	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326007780	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1104326007781	putative dimerization interface [polypeptide binding]; other site
1104326007782	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326007783	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1104326007784	catalytic triad [active]
1104326007785	conserved cis-peptide bond; other site
1104326007786	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1104326007787	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1104326007788	conserved cys residue [active]
1104326007789	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326007790	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1104326007791	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1104326007792	elongation factor G; Reviewed; Region: PRK00007
1104326007793	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1104326007794	G1 box; other site
1104326007795	putative GEF interaction site [polypeptide binding]; other site
1104326007796	GTP/Mg2+ binding site [chemical binding]; other site
1104326007797	Switch I region; other site
1104326007798	G2 box; other site
1104326007799	G3 box; other site
1104326007800	Switch II region; other site
1104326007801	G4 box; other site
1104326007802	G5 box; other site
1104326007803	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1104326007804	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1104326007805	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1104326007806	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326007807	dimerization interface [polypeptide binding]; other site
1104326007808	putative DNA binding site [nucleotide binding]; other site
1104326007809	Helix-turn-helix domain; Region: HTH_39; pfam14090
1104326007810	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1104326007811	malate dehydrogenase; Provisional; Region: PRK13529
1104326007812	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1104326007813	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1104326007814	NAD(P) binding site [chemical binding]; other site
1104326007815	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1104326007816	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1104326007817	putative acyl-acceptor binding pocket; other site
1104326007818	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
1104326007819	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1104326007820	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1104326007821	C-terminal domain interface [polypeptide binding]; other site
1104326007822	GSH binding site (G-site) [chemical binding]; other site
1104326007823	dimer interface [polypeptide binding]; other site
1104326007824	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1104326007825	dimer interface [polypeptide binding]; other site
1104326007826	N-terminal domain interface [polypeptide binding]; other site
1104326007827	substrate binding pocket (H-site) [chemical binding]; other site
1104326007828	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326007829	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326007830	substrate binding pocket [chemical binding]; other site
1104326007831	membrane-bound complex binding site; other site
1104326007832	hinge residues; other site
1104326007833	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1104326007834	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326007835	Walker A/P-loop; other site
1104326007836	ATP binding site [chemical binding]; other site
1104326007837	Q-loop/lid; other site
1104326007838	ABC transporter signature motif; other site
1104326007839	Walker B; other site
1104326007840	D-loop; other site
1104326007841	H-loop/switch region; other site
1104326007842	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326007843	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326007844	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007845	dimer interface [polypeptide binding]; other site
1104326007846	conserved gate region; other site
1104326007847	putative PBP binding loops; other site
1104326007848	ABC-ATPase subunit interface; other site
1104326007849	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326007850	Coenzyme A binding pocket [chemical binding]; other site
1104326007851	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326007852	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326007853	substrate binding pocket [chemical binding]; other site
1104326007854	membrane-bound complex binding site; other site
1104326007855	hinge residues; other site
1104326007856	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1104326007857	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1104326007858	active site
1104326007859	non-prolyl cis peptide bond; other site
1104326007860	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1104326007861	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
1104326007862	metal binding site [ion binding]; metal-binding site
1104326007863	dimer interface [polypeptide binding]; other site
1104326007864	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1104326007865	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1104326007866	AAA domain; Region: AAA_17; pfam13207
1104326007867	L-asparagine permease; Provisional; Region: PRK15049
1104326007868	PQQ-like domain; Region: PQQ_2; pfam13360
1104326007869	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1104326007870	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1104326007871	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326007872	N-terminal plug; other site
1104326007873	ligand-binding site [chemical binding]; other site
1104326007874	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1104326007875	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326007876	DNA-binding site [nucleotide binding]; DNA binding site
1104326007877	FCD domain; Region: FCD; pfam07729
1104326007878	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1104326007879	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1104326007880	NAD(P) binding site [chemical binding]; other site
1104326007881	substrate binding site [chemical binding]; other site
1104326007882	dimer interface [polypeptide binding]; other site
1104326007883	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1104326007884	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326007885	non-specific DNA binding site [nucleotide binding]; other site
1104326007886	salt bridge; other site
1104326007887	sequence-specific DNA binding site [nucleotide binding]; other site
1104326007888	Cupin domain; Region: Cupin_2; pfam07883
1104326007889	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1104326007890	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326007891	Coenzyme A binding pocket [chemical binding]; other site
1104326007892	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1104326007893	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1104326007894	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1104326007895	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1104326007896	peptide binding site [polypeptide binding]; other site
1104326007897	Virulence factor SrfB; Region: SrfB; pfam07520
1104326007898	potential frameshift: common BLAST hit: gi|296102215|ref|YP_003612361.1| putative virulence protein
1104326007899	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326007900	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1104326007901	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1104326007902	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1104326007903	tetrameric interface [polypeptide binding]; other site
1104326007904	NAD binding site [chemical binding]; other site
1104326007905	catalytic residues [active]
1104326007906	substrate binding site [chemical binding]; other site
1104326007907	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1104326007908	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007909	putative PBP binding loops; other site
1104326007910	dimer interface [polypeptide binding]; other site
1104326007911	ABC-ATPase subunit interface; other site
1104326007912	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1104326007913	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326007914	dimer interface [polypeptide binding]; other site
1104326007915	conserved gate region; other site
1104326007916	putative PBP binding loops; other site
1104326007917	ABC-ATPase subunit interface; other site
1104326007918	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
1104326007919	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326007920	Walker A/P-loop; other site
1104326007921	ATP binding site [chemical binding]; other site
1104326007922	Q-loop/lid; other site
1104326007923	ABC transporter signature motif; other site
1104326007924	Walker B; other site
1104326007925	D-loop; other site
1104326007926	H-loop/switch region; other site
1104326007927	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1104326007928	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1104326007929	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1104326007930	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326007931	DNA-binding site [nucleotide binding]; DNA binding site
1104326007932	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326007933	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326007934	homodimer interface [polypeptide binding]; other site
1104326007935	catalytic residue [active]
1104326007936	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1104326007937	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1104326007938	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1104326007939	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1104326007940	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
1104326007941	heat-inducible protein; Provisional; Region: PRK10449
1104326007942	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1104326007943	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1104326007944	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1104326007945	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1104326007946	dimer interface [polypeptide binding]; other site
1104326007947	PYR/PP interface [polypeptide binding]; other site
1104326007948	TPP binding site [chemical binding]; other site
1104326007949	substrate binding site [chemical binding]; other site
1104326007950	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1104326007951	Domain of unknown function; Region: EKR; pfam10371
1104326007952	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1104326007953	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1104326007954	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1104326007955	TPP-binding site [chemical binding]; other site
1104326007956	dimer interface [polypeptide binding]; other site
1104326007957	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326007958	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1104326007959	trimer interface [polypeptide binding]; other site
1104326007960	eyelet of channel; other site
1104326007961	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
1104326007962	Predicted membrane protein [Function unknown]; Region: COG3326
1104326007963	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1104326007964	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1104326007965	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1104326007966	Ligand Binding Site [chemical binding]; other site
1104326007967	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1104326007968	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1104326007969	ATP binding site [chemical binding]; other site
1104326007970	Mg++ binding site [ion binding]; other site
1104326007971	motif III; other site
1104326007972	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326007973	nucleotide binding region [chemical binding]; other site
1104326007974	ATP-binding site [chemical binding]; other site
1104326007975	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1104326007976	putative RNA binding site [nucleotide binding]; other site
1104326007977	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1104326007978	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1104326007979	Cl binding site [ion binding]; other site
1104326007980	oligomer interface [polypeptide binding]; other site
1104326007981	HAMP domain; Region: HAMP; pfam00672
1104326007982	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1104326007983	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326007984	dimer interface [polypeptide binding]; other site
1104326007985	putative CheW interface [polypeptide binding]; other site
1104326007986	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1104326007987	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1104326007988	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1104326007989	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326007990	metal binding site [ion binding]; metal-binding site
1104326007991	active site
1104326007992	I-site; other site
1104326007993	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326007994	PAS domain S-box; Region: sensory_box; TIGR00229
1104326007995	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326007996	putative active site [active]
1104326007997	heme pocket [chemical binding]; other site
1104326007998	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326007999	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326008000	metal binding site [ion binding]; metal-binding site
1104326008001	active site
1104326008002	I-site; other site
1104326008003	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1104326008004	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
1104326008005	conserved cys residue [active]
1104326008006	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1104326008007	Protein of unknown function (DUF770); Region: DUF770; cl01402
1104326008008	Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681
1104326008009	NmrA-like family; Region: NmrA; pfam05368
1104326008010	NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs; Region: NmrA_like_SDR_a; cd05251
1104326008011	NADP binding site [chemical binding]; other site
1104326008012	active site
1104326008013	regulatory binding site [polypeptide binding]; other site
1104326008014	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1104326008015	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326008016	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326008017	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_2; cd08464
1104326008018	putative substrate binding pocket [chemical binding]; other site
1104326008019	putative dimerization interface [polypeptide binding]; other site
1104326008020	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326008021	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326008022	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1104326008023	putative effector binding pocket; other site
1104326008024	putative dimerization interface [polypeptide binding]; other site
1104326008025	potential frameshift: common BLAST hit: gi|389871061|ref|YP_006378480.1| isoflavone reductase
1104326008026	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1104326008027	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
1104326008028	NAD(P) binding site [chemical binding]; other site
1104326008029	active site lysine
1104326008030	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1104326008031	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326008032	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326008033	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326008034	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1104326008035	NAD(P) binding site [chemical binding]; other site
1104326008036	active site
1104326008037	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1104326008038	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1104326008039	peptide binding site [polypeptide binding]; other site
1104326008040	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1104326008041	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1104326008042	putative active site [active]
1104326008043	Zn binding site [ion binding]; other site
1104326008044	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1104326008045	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1104326008046	active site
1104326008047	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1104326008048	dimer interface [polypeptide binding]; other site
1104326008049	catalytic triad [active]
1104326008050	peroxidatic and resolving cysteines [active]
1104326008051	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
1104326008052	active site
1104326008053	catalytic residues [active]
1104326008054	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1104326008055	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1104326008056	PAS domain; Region: PAS; smart00091
1104326008057	putative active site [active]
1104326008058	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326008059	Walker A motif; other site
1104326008060	ATP binding site [chemical binding]; other site
1104326008061	Walker B motif; other site
1104326008062	arginine finger; other site
1104326008063	hypothetical protein; Provisional; Region: PRK05415
1104326008064	Domain of unknown function (DUF697); Region: DUF697; cl12064
1104326008065	Predicted ATPase [General function prediction only]; Region: COG3106
1104326008066	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326008067	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326008068	DNA binding site [nucleotide binding]
1104326008069	domain linker motif; other site
1104326008070	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1104326008071	putative dimerization interface [polypeptide binding]; other site
1104326008072	putative ligand binding site [chemical binding]; other site
1104326008073	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
1104326008074	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1104326008075	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1104326008076	Walker A/P-loop; other site
1104326008077	ATP binding site [chemical binding]; other site
1104326008078	Q-loop/lid; other site
1104326008079	ABC transporter signature motif; other site
1104326008080	Walker B; other site
1104326008081	D-loop; other site
1104326008082	H-loop/switch region; other site
1104326008083	TOBE domain; Region: TOBE; pfam03459
1104326008084	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1104326008085	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326008086	motif II; other site
1104326008087	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1104326008088	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1104326008089	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1104326008090	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1104326008091	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326008092	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326008093	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326008094	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1104326008095	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1104326008096	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1104326008097	putative NAD(P) binding site [chemical binding]; other site
1104326008098	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1104326008099	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008100	dimer interface [polypeptide binding]; other site
1104326008101	conserved gate region; other site
1104326008102	putative PBP binding loops; other site
1104326008103	ABC-ATPase subunit interface; other site
1104326008104	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008105	dimer interface [polypeptide binding]; other site
1104326008106	conserved gate region; other site
1104326008107	putative PBP binding loops; other site
1104326008108	ABC-ATPase subunit interface; other site
1104326008109	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1104326008110	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1104326008111	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1104326008112	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
1104326008113	active site
1104326008114	homodimer interface [polypeptide binding]; other site
1104326008115	catalytic site [active]
1104326008116	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1104326008117	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1104326008118	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1104326008119	phage shock protein C; Region: phageshock_pspC; TIGR02978
1104326008120	phage shock protein B; Provisional; Region: pspB; PRK09458
1104326008121	phage shock protein PspA; Provisional; Region: PRK10698
1104326008122	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1104326008123	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326008124	Walker A motif; other site
1104326008125	ATP binding site [chemical binding]; other site
1104326008126	Walker B motif; other site
1104326008127	arginine finger; other site
1104326008128	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1104326008129	nucleophilic elbow; other site
1104326008130	catalytic triad; other site
1104326008131	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1104326008132	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1104326008133	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326008134	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326008135	ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; Region: ArpD; COG4618
1104326008136	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326008137	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1104326008138	Walker A/P-loop; other site
1104326008139	ATP binding site [chemical binding]; other site
1104326008140	Q-loop/lid; other site
1104326008141	ABC transporter signature motif; other site
1104326008142	Walker B; other site
1104326008143	D-loop; other site
1104326008144	H-loop/switch region; other site
1104326008145	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1104326008146	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1104326008147	peptide binding site [polypeptide binding]; other site
1104326008148	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1104326008149	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008150	dimer interface [polypeptide binding]; other site
1104326008151	conserved gate region; other site
1104326008152	putative PBP binding loops; other site
1104326008153	ABC-ATPase subunit interface; other site
1104326008154	hypothetical protein; Provisional; Region: PRK09951
1104326008155	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1104326008156	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1104326008157	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1104326008158	active site
1104326008159	DNA binding site [nucleotide binding]
1104326008160	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1104326008161	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1104326008162	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1104326008163	Catalytic site [active]
1104326008164	Phage-related protein, tail component [Function unknown]; Region: COG4733
1104326008165	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1104326008166	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1104326008167	Interdomain contacts; other site
1104326008168	Cytokine receptor motif; other site
1104326008169	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1104326008170	Uncharacterized protein family (UPF0257); Region: UPF0257; cl14672
1104326008171	Phage terminase large subunit; Region: Terminase_3; cl12054
1104326008172	Terminase-like family; Region: Terminase_6; pfam03237
1104326008173	Terminase small subunit; Region: Terminase_2; cl01513
1104326008174	Terminase small subunit; Region: Terminase_2; pfam03592
1104326008175	Uncharacterized small protein (DUF2158); Region: DUF2158; pfam09926
1104326008176	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1104326008177	Inhibitor of vertebrate lysozyme (Ivy); Region: Ivy; cl07428
1104326008178	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1104326008179	catalytic residues [active]
1104326008180	Antitermination protein; Region: Antiterm; pfam03589
1104326008181	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
1104326008182	Antitermination protein; Region: Antiterm; pfam03589
1104326008183	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
1104326008184	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1104326008185	DinI-like family; Region: DinI; pfam06183
1104326008186	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326008187	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1104326008188	active site
1104326008189	metal binding site [ion binding]; metal-binding site
1104326008190	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1104326008191	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1104326008192	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326008193	AAA domain; Region: AAA_21; pfam13304
1104326008194	Walker A/P-loop; other site
1104326008195	ATP binding site [chemical binding]; other site
1104326008196	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326008197	Walker B; other site
1104326008198	D-loop; other site
1104326008199	H-loop/switch region; other site
1104326008200	Replication protein P; Region: Phage_lambda_P; pfam06992
1104326008201	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
1104326008202	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1104326008203	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1104326008204	transcriptional repressor DicA; Reviewed; Region: PRK09706
1104326008205	non-specific DNA binding site [nucleotide binding]; other site
1104326008206	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1104326008207	sequence-specific DNA binding site [nucleotide binding]; other site
1104326008208	salt bridge; other site
1104326008209	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1104326008210	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1104326008211	RecT family; Region: RecT; pfam03837
1104326008212	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
1104326008213	Helix-turn-helix domain; Region: HTH_17; cl17695
1104326008214	integrase; Provisional; Region: PRK09692
1104326008215	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1104326008216	active site
1104326008217	Int/Topo IB signature motif; other site
1104326008218	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1104326008219	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1104326008220	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008221	dimer interface [polypeptide binding]; other site
1104326008222	conserved gate region; other site
1104326008223	putative PBP binding loops; other site
1104326008224	ABC-ATPase subunit interface; other site
1104326008225	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1104326008226	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326008227	Walker A/P-loop; other site
1104326008228	ATP binding site [chemical binding]; other site
1104326008229	Q-loop/lid; other site
1104326008230	ABC transporter signature motif; other site
1104326008231	Walker B; other site
1104326008232	D-loop; other site
1104326008233	H-loop/switch region; other site
1104326008234	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1104326008235	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1104326008236	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326008237	Walker A/P-loop; other site
1104326008238	ATP binding site [chemical binding]; other site
1104326008239	Q-loop/lid; other site
1104326008240	ABC transporter signature motif; other site
1104326008241	Walker B; other site
1104326008242	D-loop; other site
1104326008243	H-loop/switch region; other site
1104326008244	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1104326008245	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326008246	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326008247	dimerization interface [polypeptide binding]; other site
1104326008248	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326008249	dimer interface [polypeptide binding]; other site
1104326008250	phosphorylation site [posttranslational modification]
1104326008251	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326008252	ATP binding site [chemical binding]; other site
1104326008253	Mg2+ binding site [ion binding]; other site
1104326008254	G-X-G motif; other site
1104326008255	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1104326008256	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326008257	active site
1104326008258	phosphorylation site [posttranslational modification]
1104326008259	intermolecular recognition site; other site
1104326008260	dimerization interface [polypeptide binding]; other site
1104326008261	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326008262	DNA binding site [nucleotide binding]
1104326008263	ABC transporter transmembrane region; Region: ABC_membrane_3; pfam13748
1104326008264	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1104326008265	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326008266	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1104326008267	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1104326008268	NAD binding site [chemical binding]; other site
1104326008269	homotetramer interface [polypeptide binding]; other site
1104326008270	homodimer interface [polypeptide binding]; other site
1104326008271	substrate binding site [chemical binding]; other site
1104326008272	active site
1104326008273	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1104326008274	exoribonuclease II; Provisional; Region: PRK05054
1104326008275	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1104326008276	RNB domain; Region: RNB; pfam00773
1104326008277	S1 RNA binding domain; Region: S1; pfam00575
1104326008278	RNase II stability modulator; Provisional; Region: PRK10060
1104326008279	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326008280	putative active site [active]
1104326008281	heme pocket [chemical binding]; other site
1104326008282	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326008283	metal binding site [ion binding]; metal-binding site
1104326008284	active site
1104326008285	I-site; other site
1104326008286	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326008287	enoyl-CoA hydratase; Validated; Region: PRK08788
1104326008288	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1104326008289	substrate binding site [chemical binding]; other site
1104326008290	oxyanion hole (OAH) forming residues; other site
1104326008291	trimer interface [polypeptide binding]; other site
1104326008292	hypothetical protein; Provisional; Region: PRK13658
1104326008293	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1104326008294	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1104326008295	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326008296	lipoprotein; Provisional; Region: PRK10540
1104326008297	translation initiation factor Sui1; Validated; Region: PRK06824
1104326008298	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1104326008299	putative rRNA binding site [nucleotide binding]; other site
1104326008300	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1104326008301	active site
1104326008302	dimer interface [polypeptide binding]; other site
1104326008303	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1104326008304	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1104326008305	binding surface
1104326008306	TPR motif; other site
1104326008307	Predicted membrane protein [Function unknown]; Region: COG3771
1104326008308	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1104326008309	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1104326008310	active site
1104326008311	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1104326008312	dimerization interface [polypeptide binding]; other site
1104326008313	active site
1104326008314	aconitate hydratase; Validated; Region: PRK09277
1104326008315	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1104326008316	substrate binding site [chemical binding]; other site
1104326008317	ligand binding site [chemical binding]; other site
1104326008318	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1104326008319	substrate binding site [chemical binding]; other site
1104326008320	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1104326008321	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326008322	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1104326008323	substrate binding site [chemical binding]; other site
1104326008324	putative dimerization interface [polypeptide binding]; other site
1104326008325	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1104326008326	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1104326008327	active site
1104326008328	interdomain interaction site; other site
1104326008329	putative metal-binding site [ion binding]; other site
1104326008330	nucleotide binding site [chemical binding]; other site
1104326008331	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1104326008332	domain I; other site
1104326008333	DNA binding groove [nucleotide binding]
1104326008334	phosphate binding site [ion binding]; other site
1104326008335	domain II; other site
1104326008336	domain III; other site
1104326008337	nucleotide binding site [chemical binding]; other site
1104326008338	catalytic site [active]
1104326008339	domain IV; other site
1104326008340	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1104326008341	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1104326008342	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1104326008343	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1104326008344	hypothetical protein; Provisional; Region: PRK11037
1104326008345	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1104326008346	putative inner membrane peptidase; Provisional; Region: PRK11778
1104326008347	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1104326008348	tandem repeat interface [polypeptide binding]; other site
1104326008349	oligomer interface [polypeptide binding]; other site
1104326008350	active site residues [active]
1104326008351	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1104326008352	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1104326008353	NADP binding site [chemical binding]; other site
1104326008354	homodimer interface [polypeptide binding]; other site
1104326008355	active site
1104326008356	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1104326008357	cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Validated; Region: PRK05986
1104326008358	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1104326008359	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326008360	RNA binding surface [nucleotide binding]; other site
1104326008361	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1104326008362	probable active site [active]
1104326008363	hypothetical protein; Provisional; Region: PRK11630
1104326008364	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1104326008365	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1104326008366	active site
1104326008367	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1104326008368	anthranilate synthase component I; Provisional; Region: PRK13564
1104326008369	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1104326008370	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1104326008371	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1104326008372	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1104326008373	glutamine binding [chemical binding]; other site
1104326008374	catalytic triad [active]
1104326008375	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1104326008376	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1104326008377	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1104326008378	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1104326008379	active site
1104326008380	ribulose/triose binding site [chemical binding]; other site
1104326008381	phosphate binding site [ion binding]; other site
1104326008382	substrate (anthranilate) binding pocket [chemical binding]; other site
1104326008383	product (indole) binding pocket [chemical binding]; other site
1104326008384	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1104326008385	active site
1104326008386	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1104326008387	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1104326008388	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326008389	catalytic residue [active]
1104326008390	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1104326008391	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1104326008392	substrate binding site [chemical binding]; other site
1104326008393	active site
1104326008394	catalytic residues [active]
1104326008395	heterodimer interface [polypeptide binding]; other site
1104326008396	putative inner membrane protein; Provisional; Region: PRK11099
1104326008397	Sulphur transport; Region: Sulf_transp; pfam04143
1104326008398	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1104326008399	CPxP  motif; other site
1104326008400	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326008401	Ligand Binding Site [chemical binding]; other site
1104326008402	TolA C-terminal; Region: TolA; pfam06519
1104326008403	outer membrane protein W; Provisional; Region: PRK10959
1104326008404	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1104326008405	hypothetical protein; Provisional; Region: PRK02868
1104326008406	intracellular septation protein A; Reviewed; Region: PRK00259
1104326008407	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1104326008408	transport protein TonB; Provisional; Region: PRK10819
1104326008409	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1104326008410	YciI-like protein; Reviewed; Region: PRK11370
1104326008411	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326008412	MarR family; Region: MarR_2; pfam12802
1104326008413	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326008414	Coenzyme A binding pocket [chemical binding]; other site
1104326008415	leucine export protein LeuE; Provisional; Region: PRK10958
1104326008416	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1104326008417	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1104326008418	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1104326008419	putative active site [active]
1104326008420	catalytic site [active]
1104326008421	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1104326008422	putative active site [active]
1104326008423	catalytic site [active]
1104326008424	dsDNA-mimic protein; Reviewed; Region: PRK05094
1104326008425	Ion transport protein; Region: Ion_trans; pfam00520
1104326008426	Ion channel; Region: Ion_trans_2; pfam07885
1104326008427	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1104326008428	Double zinc ribbon; Region: DZR; pfam12773
1104326008429	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1104326008430	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326008431	Walker A/P-loop; other site
1104326008432	ATP binding site [chemical binding]; other site
1104326008433	Q-loop/lid; other site
1104326008434	ABC transporter signature motif; other site
1104326008435	Walker B; other site
1104326008436	D-loop; other site
1104326008437	H-loop/switch region; other site
1104326008438	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1104326008439	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1104326008440	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326008441	Walker A/P-loop; other site
1104326008442	ATP binding site [chemical binding]; other site
1104326008443	Q-loop/lid; other site
1104326008444	ABC transporter signature motif; other site
1104326008445	Walker B; other site
1104326008446	D-loop; other site
1104326008447	H-loop/switch region; other site
1104326008448	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1104326008449	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1104326008450	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1104326008451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008452	dimer interface [polypeptide binding]; other site
1104326008453	conserved gate region; other site
1104326008454	putative PBP binding loops; other site
1104326008455	ABC-ATPase subunit interface; other site
1104326008456	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1104326008457	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008458	dimer interface [polypeptide binding]; other site
1104326008459	conserved gate region; other site
1104326008460	putative PBP binding loops; other site
1104326008461	ABC-ATPase subunit interface; other site
1104326008462	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1104326008463	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1104326008464	peptide binding site [polypeptide binding]; other site
1104326008465	hypothetical protein; Provisional; Region: PRK11111
1104326008466	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1104326008467	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1104326008468	putative catalytic cysteine [active]
1104326008469	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1104326008470	putative active site [active]
1104326008471	metal binding site [ion binding]; metal-binding site
1104326008472	thymidine kinase; Provisional; Region: PRK04296
1104326008473	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1104326008474	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1104326008475	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1104326008476	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1104326008477	active site
1104326008478	tetramer interface; other site
1104326008479	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326008480	active site
1104326008481	response regulator of RpoS; Provisional; Region: PRK10693
1104326008482	phosphorylation site [posttranslational modification]
1104326008483	intermolecular recognition site; other site
1104326008484	dimerization interface [polypeptide binding]; other site
1104326008485	hypothetical protein; Provisional; Region: PRK10279
1104326008486	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1104326008487	active site
1104326008488	nucleophile elbow; other site
1104326008489	SEC-C motif; Region: SEC-C; pfam02810
1104326008490	hypothetical protein; Provisional; Region: PRK04233
1104326008491	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1104326008492	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1104326008493	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1104326008494	putative active site [active]
1104326008495	putative substrate binding site [chemical binding]; other site
1104326008496	putative cosubstrate binding site; other site
1104326008497	catalytic site [active]
1104326008498	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1104326008499	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
1104326008500	putative DNA binding site [nucleotide binding]; other site
1104326008501	putative Zn2+ binding site [ion binding]; other site
1104326008502	AsnC family; Region: AsnC_trans_reg; pfam01037
1104326008503	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1104326008504	EamA-like transporter family; Region: EamA; pfam00892
1104326008505	EamA-like transporter family; Region: EamA; pfam00892
1104326008506	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1104326008507	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1104326008508	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1104326008509	4Fe-4S binding domain; Region: Fer4; cl02805
1104326008510	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1104326008511	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1104326008512	[4Fe-4S] binding site [ion binding]; other site
1104326008513	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326008514	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326008515	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326008516	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1104326008517	molybdopterin cofactor binding site; other site
1104326008518	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1104326008519	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1104326008520	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1104326008521	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326008522	dimerization interface [polypeptide binding]; other site
1104326008523	Histidine kinase; Region: HisKA_3; pfam07730
1104326008524	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326008525	ATP binding site [chemical binding]; other site
1104326008526	Mg2+ binding site [ion binding]; other site
1104326008527	G-X-G motif; other site
1104326008528	transcriptional regulator NarL; Provisional; Region: PRK10651
1104326008529	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326008530	active site
1104326008531	phosphorylation site [posttranslational modification]
1104326008532	intermolecular recognition site; other site
1104326008533	dimerization interface [polypeptide binding]; other site
1104326008534	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326008535	DNA binding residues [nucleotide binding]
1104326008536	dimerization interface [polypeptide binding]; other site
1104326008537	putative invasin; Provisional; Region: PRK10177
1104326008538	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1104326008539	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1104326008540	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1104326008541	[4Fe-4S] binding site [ion binding]; other site
1104326008542	molybdopterin cofactor binding site; other site
1104326008543	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1104326008544	molybdopterin cofactor binding site; other site
1104326008545	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1104326008546	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1104326008547	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1104326008548	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326008549	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326008550	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1104326008551	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1104326008552	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1104326008553	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1104326008554	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1104326008555	Walker A/P-loop; other site
1104326008556	ATP binding site [chemical binding]; other site
1104326008557	Q-loop/lid; other site
1104326008558	ABC transporter signature motif; other site
1104326008559	Walker B; other site
1104326008560	D-loop; other site
1104326008561	H-loop/switch region; other site
1104326008562	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1104326008563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326008564	dimer interface [polypeptide binding]; other site
1104326008565	conserved gate region; other site
1104326008566	putative PBP binding loops; other site
1104326008567	ABC-ATPase subunit interface; other site
1104326008568	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1104326008569	NMT1-like family; Region: NMT1_2; pfam13379
1104326008570	Nitrate and nitrite sensing; Region: NIT; pfam08376
1104326008571	ANTAR domain; Region: ANTAR; pfam03861
1104326008572	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1104326008573	Cache domain; Region: Cache_1; pfam02743
1104326008574	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326008575	dimerization interface [polypeptide binding]; other site
1104326008576	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1104326008577	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326008578	dimer interface [polypeptide binding]; other site
1104326008579	putative CheW interface [polypeptide binding]; other site
1104326008580	Domain of unknown function (DUF1883); Region: DUF1883; pfam08980
1104326008581	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
1104326008582	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1104326008583	putative active site pocket [active]
1104326008584	dimerization interface [polypeptide binding]; other site
1104326008585	putative catalytic residue [active]
1104326008586	cation transport regulator; Reviewed; Region: chaB; PRK09582
1104326008587	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1104326008588	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1104326008589	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1104326008590	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1104326008591	hypothetical protein; Provisional; Region: PRK10941
1104326008592	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1104326008593	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1104326008594	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326008595	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1104326008596	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1104326008597	RF-1 domain; Region: RF-1; pfam00472
1104326008598	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1104326008599	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1104326008600	tRNA; other site
1104326008601	putative tRNA binding site [nucleotide binding]; other site
1104326008602	putative NADP binding site [chemical binding]; other site
1104326008603	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1104326008604	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1104326008605	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1104326008606	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1104326008607	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1104326008608	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1104326008609	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1104326008610	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1104326008611	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326008612	active site
1104326008613	putative transporter; Provisional; Region: PRK11660
1104326008614	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1104326008615	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1104326008616	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1104326008617	Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047
1104326008618	Helix-Turn-Helix DNA binding domain of the transcription regulators NolA and AlbR; Region: HTH_NolA-AlbR; cd04788
1104326008619	DNA binding residues [nucleotide binding]
1104326008620	putative dimer interface [polypeptide binding]; other site
1104326008621	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1104326008622	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1104326008623	hypothetical protein; Provisional; Region: PRK10692
1104326008624	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1104326008625	putative active site [active]
1104326008626	catalytic residue [active]
1104326008627	GTP-binding protein YchF; Reviewed; Region: PRK09601
1104326008628	YchF GTPase; Region: YchF; cd01900
1104326008629	G1 box; other site
1104326008630	GTP/Mg2+ binding site [chemical binding]; other site
1104326008631	Switch I region; other site
1104326008632	G2 box; other site
1104326008633	Switch II region; other site
1104326008634	G3 box; other site
1104326008635	G4 box; other site
1104326008636	G5 box; other site
1104326008637	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1104326008638	YCII-related domain; Region: YCII; cl00999
1104326008639	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1104326008640	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1104326008641	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cl15768
1104326008642	PAAR motif; Region: PAAR_motif; pfam05488
1104326008643	RHS Repeat; Region: RHS_repeat; pfam05593
1104326008644	RHS Repeat; Region: RHS_repeat; pfam05593
1104326008645	RHS Repeat; Region: RHS_repeat; cl11982
1104326008646	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1104326008647	RHS Repeat; Region: RHS_repeat; pfam05593
1104326008648	RHS Repeat; Region: RHS_repeat; pfam05593
1104326008649	RHS Repeat; Region: RHS_repeat; cl11982
1104326008650	RHS Repeat; Region: RHS_repeat; pfam05593
1104326008651	RHS Repeat; Region: RHS_repeat; pfam05593
1104326008652	RHS protein; Region: RHS; pfam03527
1104326008653	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1104326008654	Domain of unknown function (DUF1795); Region: DUF1795; cl02256
1104326008655	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1104326008656	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1104326008657	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1104326008658	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1104326008659	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1104326008660	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1104326008661	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
1104326008662	potential frameshift: common BLAST hit: gi|365970968|ref|YP_004952529.1| ankyrin
1104326008663	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1104326008664	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1104326008665	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1104326008666	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1104326008667	active site
1104326008668	ATP binding site [chemical binding]; other site
1104326008669	substrate binding site [chemical binding]; other site
1104326008670	activation loop (A-loop); other site
1104326008671	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1104326008672	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326008673	Walker A motif; other site
1104326008674	ATP binding site [chemical binding]; other site
1104326008675	Walker B motif; other site
1104326008676	arginine finger; other site
1104326008677	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326008678	Walker A motif; other site
1104326008679	ATP binding site [chemical binding]; other site
1104326008680	Walker B motif; other site
1104326008681	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1104326008682	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1104326008683	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1104326008684	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1104326008685	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1104326008686	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
1104326008687	ImpE protein; Region: ImpE; pfam07024
1104326008688	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1104326008689	active site
1104326008690	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1104326008691	phosphopeptide binding site; other site
1104326008692	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
1104326008693	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1104326008694	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
1104326008695	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1104326008696	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1104326008697	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1104326008698	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
1104326008699	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1104326008700	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; pfam09867
1104326008701	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
1104326008702	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1104326008703	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1104326008704	hypothetical protein; Provisional; Region: PRK07033
1104326008705	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1104326008706	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326008707	ligand binding site [chemical binding]; other site
1104326008708	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1104326008709	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1104326008710	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1104326008711	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
1104326008712	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1104326008713	putative molybdopterin cofactor binding site [chemical binding]; other site
1104326008714	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1104326008715	putative molybdopterin cofactor binding site; other site
1104326008716	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326008717	membrane-bound complex binding site; other site
1104326008718	hinge residues; other site
1104326008719	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
1104326008720	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1104326008721	putative di-iron ligands [ion binding]; other site
1104326008722	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1104326008723	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1104326008724	conserved cys residue [active]
1104326008725	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1104326008726	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1104326008727	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1104326008728	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1104326008729	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326008730	putative substrate translocation pore; other site
1104326008731	Cupin; Region: Cupin_6; pfam12852
1104326008732	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326008733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326008734	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326008735	putative symporter YagG; Provisional; Region: PRK09669
1104326008736	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1104326008737	trehalase; Provisional; Region: treA; PRK13271
1104326008738	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1104326008739	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1104326008740	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326008741	N-terminal plug; other site
1104326008742	ligand-binding site [chemical binding]; other site
1104326008743	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1104326008744	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1104326008745	Flagellar regulator YcgR; Region: YcgR; pfam07317
1104326008746	PilZ domain; Region: PilZ; pfam07238
1104326008747	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1104326008748	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326008749	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326008750	catalytic residue [active]
1104326008751	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1104326008752	dimer interface [polypeptide binding]; other site
1104326008753	catalytic triad [active]
1104326008754	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1104326008755	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1104326008756	TrkA-C domain; Region: TrkA_C; pfam02080
1104326008757	Transporter associated domain; Region: CorC_HlyC; smart01091
1104326008758	alanine racemase; Reviewed; Region: dadX; PRK03646
1104326008759	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1104326008760	active site
1104326008761	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1104326008762	substrate binding site [chemical binding]; other site
1104326008763	catalytic residues [active]
1104326008764	dimer interface [polypeptide binding]; other site
1104326008765	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1104326008766	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1104326008767	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1104326008768	SpoVR family protein; Provisional; Region: PRK11767
1104326008769	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1104326008770	fatty acid metabolism regulator; Provisional; Region: PRK04984
1104326008771	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326008772	DNA-binding site [nucleotide binding]; DNA binding site
1104326008773	FadR C-terminal domain; Region: FadR_C; pfam07840
1104326008774	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1104326008775	disulfide bond formation protein B; Provisional; Region: PRK01749
1104326008776	hypothetical protein; Provisional; Region: PRK05170
1104326008777	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1104326008778	hypothetical protein; Provisional; Region: PRK10691
1104326008779	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1104326008780	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1104326008781	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1104326008782	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1104326008783	cell division inhibitor MinD; Provisional; Region: PRK10818
1104326008784	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1104326008785	Switch I; other site
1104326008786	Switch II; other site
1104326008787	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1104326008788	ribonuclease D; Provisional; Region: PRK10829
1104326008789	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1104326008790	catalytic site [active]
1104326008791	putative active site [active]
1104326008792	putative substrate binding site [chemical binding]; other site
1104326008793	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1104326008794	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1104326008795	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1104326008796	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1104326008797	acyl-activating enzyme (AAE) consensus motif; other site
1104326008798	putative AMP binding site [chemical binding]; other site
1104326008799	putative active site [active]
1104326008800	putative CoA binding site [chemical binding]; other site
1104326008801	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1104326008802	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1104326008803	Glycoprotease family; Region: Peptidase_M22; pfam00814
1104326008804	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1104326008805	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1104326008806	ATP binding site [chemical binding]; other site
1104326008807	DEAD_2; Region: DEAD_2; pfam06733
1104326008808	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1104326008809	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1104326008810	homotrimer interaction site [polypeptide binding]; other site
1104326008811	putative active site [active]
1104326008812	hypothetical protein; Provisional; Region: PRK05114
1104326008813	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1104326008814	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1104326008815	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1104326008816	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1104326008817	putative active site [active]
1104326008818	putative CoA binding site [chemical binding]; other site
1104326008819	nudix motif; other site
1104326008820	metal binding site [ion binding]; metal-binding site
1104326008821	L-serine deaminase; Provisional; Region: PRK15023
1104326008822	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1104326008823	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1104326008824	phage resistance protein; Provisional; Region: PRK10551
1104326008825	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1104326008826	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326008827	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1104326008828	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1104326008829	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1104326008830	Transporter associated domain; Region: CorC_HlyC; smart01091
1104326008831	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1104326008832	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1104326008833	active pocket/dimerization site; other site
1104326008834	active site
1104326008835	phosphorylation site [posttranslational modification]
1104326008836	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1104326008837	active site
1104326008838	phosphorylation site [posttranslational modification]
1104326008839	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1104326008840	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1104326008841	hypothetical protein; Provisional; Region: PRK02913
1104326008842	hypothetical protein; Provisional; Region: PRK11469
1104326008843	Domain of unknown function DUF; Region: DUF204; pfam02659
1104326008844	Domain of unknown function DUF; Region: DUF204; pfam02659
1104326008845	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1104326008846	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326008847	S-adenosylmethionine binding site [chemical binding]; other site
1104326008848	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1104326008849	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1104326008850	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1104326008851	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1104326008852	DNA-binding site [nucleotide binding]; DNA binding site
1104326008853	RNA-binding motif; other site
1104326008854	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
1104326008855	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1104326008856	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1104326008857	YebO-like protein; Region: YebO; pfam13974
1104326008858	PhoPQ regulatory protein; Provisional; Region: PRK10299
1104326008859	YobH-like protein; Region: YobH; pfam13996
1104326008860	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1104326008861	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326008862	dimerization interface [polypeptide binding]; other site
1104326008863	putative Zn2+ binding site [ion binding]; other site
1104326008864	putative DNA binding site [nucleotide binding]; other site
1104326008865	Bacterial transcriptional regulator; Region: IclR; pfam01614
1104326008866	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326008867	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326008868	putative substrate translocation pore; other site
1104326008869	heat shock protein HtpX; Provisional; Region: PRK05457
1104326008870	carboxy-terminal protease; Provisional; Region: PRK11186
1104326008871	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1104326008872	protein binding site [polypeptide binding]; other site
1104326008873	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1104326008874	Catalytic dyad [active]
1104326008875	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1104326008876	ProP expression regulator; Provisional; Region: PRK04950
1104326008877	ProQ/FINO family; Region: ProQ; pfam04352
1104326008878	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1104326008879	GAF domain; Region: GAF_2; pfam13185
1104326008880	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1104326008881	Paraquat-inducible protein A; Region: PqiA; pfam04403
1104326008882	Paraquat-inducible protein A; Region: PqiA; pfam04403
1104326008883	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1104326008884	mce related protein; Region: MCE; pfam02470
1104326008885	mce related protein; Region: MCE; pfam02470
1104326008886	mce related protein; Region: MCE; pfam02470
1104326008887	mce related protein; Region: MCE; pfam02470
1104326008888	mce related protein; Region: MCE; pfam02470
1104326008889	mce related protein; Region: MCE; pfam02470
1104326008890	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1104326008891	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326008892	S-adenosylmethionine binding site [chemical binding]; other site
1104326008893	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1104326008894	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1104326008895	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1104326008896	active site
1104326008897	metal binding site [ion binding]; metal-binding site
1104326008898	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1104326008899	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1104326008900	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1104326008901	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1104326008902	CopC domain; Region: CopC; cl01012
1104326008903	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1104326008904	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1104326008905	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1104326008906	exodeoxyribonuclease X; Provisional; Region: PRK07983
1104326008907	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1104326008908	active site
1104326008909	catalytic site [active]
1104326008910	substrate binding site [chemical binding]; other site
1104326008911	protease 2; Provisional; Region: PRK10115
1104326008912	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1104326008913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1104326008914	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1104326008915	putative metal binding site [ion binding]; other site
1104326008916	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1104326008917	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326008918	ATP-grasp domain; Region: ATP-grasp; pfam02222
1104326008919	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1104326008920	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1104326008921	active site
1104326008922	intersubunit interface [polypeptide binding]; other site
1104326008923	catalytic residue [active]
1104326008924	phosphogluconate dehydratase; Validated; Region: PRK09054
1104326008925	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1104326008926	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1104326008927	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1104326008928	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1104326008929	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1104326008930	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326008931	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1104326008932	putative active site [active]
1104326008933	pyruvate kinase; Provisional; Region: PRK05826
1104326008934	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1104326008935	domain interfaces; other site
1104326008936	active site
1104326008937	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1104326008938	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1104326008939	putative acyl-acceptor binding pocket; other site
1104326008940	putative peptidase; Provisional; Region: PRK11649
1104326008941	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1104326008942	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326008943	Peptidase family M23; Region: Peptidase_M23; pfam01551
1104326008944	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1104326008945	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1104326008946	metal binding site [ion binding]; metal-binding site
1104326008947	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1104326008948	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1104326008949	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1104326008950	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326008951	ABC-ATPase subunit  interface; other site
1104326008952	dimer interface [polypeptide binding]; other site
1104326008953	putative PBP binding regions; other site
1104326008954	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1104326008955	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326008956	Walker A motif; other site
1104326008957	ATP binding site [chemical binding]; other site
1104326008958	Walker B motif; other site
1104326008959	arginine finger; other site
1104326008960	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1104326008961	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1104326008962	RuvA N terminal domain; Region: RuvA_N; pfam01330
1104326008963	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1104326008964	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1104326008965	active site
1104326008966	putative DNA-binding cleft [nucleotide binding]; other site
1104326008967	dimer interface [polypeptide binding]; other site
1104326008968	hypothetical protein; Validated; Region: PRK00110
1104326008969	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1104326008970	nudix motif; other site
1104326008971	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1104326008972	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1104326008973	dimer interface [polypeptide binding]; other site
1104326008974	anticodon binding site; other site
1104326008975	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1104326008976	homodimer interface [polypeptide binding]; other site
1104326008977	motif 1; other site
1104326008978	active site
1104326008979	motif 2; other site
1104326008980	GAD domain; Region: GAD; pfam02938
1104326008981	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1104326008982	active site
1104326008983	motif 3; other site
1104326008984	Isochorismatase family; Region: Isochorismatase; pfam00857
1104326008985	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1104326008986	catalytic triad [active]
1104326008987	conserved cis-peptide bond; other site
1104326008988	hypothetical protein; Provisional; Region: PRK10302
1104326008989	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1104326008990	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326008991	S-adenosylmethionine binding site [chemical binding]; other site
1104326008992	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1104326008993	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326008994	S-adenosylmethionine binding site [chemical binding]; other site
1104326008995	copper homeostasis protein CutC; Provisional; Region: PRK11572
1104326008996	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1104326008997	putative metal binding site [ion binding]; other site
1104326008998	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1104326008999	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1104326009000	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1104326009001	active site
1104326009002	HIGH motif; other site
1104326009003	KMSK motif region; other site
1104326009004	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1104326009005	tRNA binding surface [nucleotide binding]; other site
1104326009006	anticodon binding site; other site
1104326009007	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1104326009008	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1104326009009	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326009010	putative substrate translocation pore; other site
1104326009011	Flagellar protein FlhE; Region: FlhE; pfam06366
1104326009012	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1104326009013	FHIPEP family; Region: FHIPEP; pfam00771
1104326009014	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1104326009015	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1104326009016	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1104326009017	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1104326009018	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009019	active site
1104326009020	phosphorylation site [posttranslational modification]
1104326009021	intermolecular recognition site; other site
1104326009022	dimerization interface [polypeptide binding]; other site
1104326009023	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1104326009024	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009025	active site
1104326009026	phosphorylation site [posttranslational modification]
1104326009027	intermolecular recognition site; other site
1104326009028	dimerization interface [polypeptide binding]; other site
1104326009029	CheB methylesterase; Region: CheB_methylest; pfam01339
1104326009030	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1104326009031	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1104326009032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326009033	S-adenosylmethionine binding site [chemical binding]; other site
1104326009034	methyl-accepting protein IV; Provisional; Region: PRK09793
1104326009035	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326009036	dimer interface [polypeptide binding]; other site
1104326009037	ligand binding site [chemical binding]; other site
1104326009038	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326009039	dimerization interface [polypeptide binding]; other site
1104326009040	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326009041	dimer interface [polypeptide binding]; other site
1104326009042	putative CheW interface [polypeptide binding]; other site
1104326009043	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1104326009044	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1104326009045	dimer interface [polypeptide binding]; other site
1104326009046	ligand binding site [chemical binding]; other site
1104326009047	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326009048	dimerization interface [polypeptide binding]; other site
1104326009049	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326009050	dimer interface [polypeptide binding]; other site
1104326009051	putative CheW interface [polypeptide binding]; other site
1104326009052	Spore Coat Protein U domain; Region: SCPU; pfam05229
1104326009053	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326009054	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326009055	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326009056	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1104326009057	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326009058	Spore Coat Protein U domain; Region: SCPU; pfam05229
1104326009059	Spore Coat Protein U domain; Region: SCPU; pfam05229
1104326009060	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1104326009061	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1104326009062	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1104326009063	putative CheA interaction surface; other site
1104326009064	chemotaxis protein CheA; Provisional; Region: PRK10547
1104326009065	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1104326009066	putative binding surface; other site
1104326009067	active site
1104326009068	CheY binding; Region: CheY-binding; pfam09078
1104326009069	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1104326009070	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326009071	ATP binding site [chemical binding]; other site
1104326009072	Mg2+ binding site [ion binding]; other site
1104326009073	G-X-G motif; other site
1104326009074	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1104326009075	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1104326009076	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1104326009077	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326009078	ligand binding site [chemical binding]; other site
1104326009079	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1104326009080	flagellar motor protein MotA; Validated; Region: PRK09110
1104326009081	transcriptional activator FlhC; Provisional; Region: PRK12722
1104326009082	transcriptional activator FlhD; Provisional; Region: PRK02909
1104326009083	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326009084	Ligand Binding Site [chemical binding]; other site
1104326009085	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1104326009086	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1104326009087	active site
1104326009088	homotetramer interface [polypeptide binding]; other site
1104326009089	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1104326009090	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1104326009091	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326009092	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326009093	TM-ABC transporter signature motif; other site
1104326009094	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1104326009095	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326009096	Walker A/P-loop; other site
1104326009097	ATP binding site [chemical binding]; other site
1104326009098	Q-loop/lid; other site
1104326009099	ABC transporter signature motif; other site
1104326009100	Walker B; other site
1104326009101	D-loop; other site
1104326009102	H-loop/switch region; other site
1104326009103	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326009104	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1104326009105	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1104326009106	ligand binding site [chemical binding]; other site
1104326009107	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1104326009108	Ferritin-like domain; Region: Ferritin; pfam00210
1104326009109	ferroxidase diiron center [ion binding]; other site
1104326009110	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1104326009111	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1104326009112	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
1104326009113	hypothetical protein; Provisional; Region: PRK09273
1104326009114	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1104326009115	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1104326009116	YecR-like lipoprotein; Region: YecR; pfam13992
1104326009117	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1104326009118	Ferritin-like domain; Region: Ferritin; pfam00210
1104326009119	ferroxidase diiron center [ion binding]; other site
1104326009120	tyrosine transporter TyrP; Provisional; Region: PRK15132
1104326009121	aromatic amino acid transport protein; Region: araaP; TIGR00837
1104326009122	hypothetical protein; Provisional; Region: PRK10396
1104326009123	Uncharacterized protein family (UPF0149); Region: UPF0149; pfam03695
1104326009124	SEC-C motif; Region: SEC-C; pfam02810
1104326009125	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1104326009126	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1104326009127	dimerization interface [polypeptide binding]; other site
1104326009128	ligand binding site [chemical binding]; other site
1104326009129	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326009130	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1104326009131	TM-ABC transporter signature motif; other site
1104326009132	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1104326009133	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1104326009134	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1104326009135	TM-ABC transporter signature motif; other site
1104326009136	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1104326009137	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1104326009138	Walker A/P-loop; other site
1104326009139	ATP binding site [chemical binding]; other site
1104326009140	Q-loop/lid; other site
1104326009141	ABC transporter signature motif; other site
1104326009142	Walker B; other site
1104326009143	D-loop; other site
1104326009144	H-loop/switch region; other site
1104326009145	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1104326009146	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1104326009147	Walker A/P-loop; other site
1104326009148	ATP binding site [chemical binding]; other site
1104326009149	Q-loop/lid; other site
1104326009150	ABC transporter signature motif; other site
1104326009151	Walker B; other site
1104326009152	D-loop; other site
1104326009153	H-loop/switch region; other site
1104326009154	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1104326009155	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1104326009156	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1104326009157	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1104326009158	GIY-YIG motif/motif A; other site
1104326009159	active site
1104326009160	catalytic site [active]
1104326009161	putative DNA binding site [nucleotide binding]; other site
1104326009162	metal binding site [ion binding]; metal-binding site
1104326009163	UvrB/uvrC motif; Region: UVR; pfam02151
1104326009164	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1104326009165	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1104326009166	response regulator; Provisional; Region: PRK09483
1104326009167	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009168	active site
1104326009169	phosphorylation site [posttranslational modification]
1104326009170	intermolecular recognition site; other site
1104326009171	dimerization interface [polypeptide binding]; other site
1104326009172	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326009173	DNA binding residues [nucleotide binding]
1104326009174	dimerization interface [polypeptide binding]; other site
1104326009175	hypothetical protein; Provisional; Region: PRK10613
1104326009176	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1104326009177	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1104326009178	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326009179	DNA binding residues [nucleotide binding]
1104326009180	dimerization interface [polypeptide binding]; other site
1104326009181	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1104326009182	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326009183	Walker A/P-loop; other site
1104326009184	ATP binding site [chemical binding]; other site
1104326009185	Q-loop/lid; other site
1104326009186	ABC transporter signature motif; other site
1104326009187	Walker B; other site
1104326009188	D-loop; other site
1104326009189	H-loop/switch region; other site
1104326009190	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326009191	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326009192	dimer interface [polypeptide binding]; other site
1104326009193	conserved gate region; other site
1104326009194	putative PBP binding loops; other site
1104326009195	ABC-ATPase subunit interface; other site
1104326009196	D-cysteine desulfhydrase; Validated; Region: PRK03910
1104326009197	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1104326009198	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326009199	catalytic residue [active]
1104326009200	cystine transporter subunit; Provisional; Region: PRK11260
1104326009201	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326009202	substrate binding pocket [chemical binding]; other site
1104326009203	membrane-bound complex binding site; other site
1104326009204	hinge residues; other site
1104326009205	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1104326009206	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1104326009207	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326009208	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1104326009209	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326009210	DNA binding residues [nucleotide binding]
1104326009211	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1104326009212	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326009213	S-adenosylmethionine binding site [chemical binding]; other site
1104326009214	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1104326009215	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326009216	Coenzyme A binding pocket [chemical binding]; other site
1104326009217	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1104326009218	active site
1104326009219	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
1104326009220	active site
1104326009221	WbqC-like protein family; Region: WbqC; pfam08889
1104326009222	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1104326009223	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1104326009224	inhibitor-cofactor binding pocket; inhibition site
1104326009225	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326009226	catalytic residue [active]
1104326009227	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326009228	S-adenosylmethionine binding site [chemical binding]; other site
1104326009229	Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119
1104326009230	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326009231	binding surface
1104326009232	TPR motif; other site
1104326009233	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326009234	binding surface
1104326009235	TPR motif; other site
1104326009236	TPR repeat; Region: TPR_11; pfam13414
1104326009237	flagellin; Provisional; Region: PRK12802
1104326009238	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1104326009239	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1104326009240	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1104326009241	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1104326009242	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1104326009243	flagellar protein FliS; Validated; Region: fliS; PRK05685
1104326009244	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1104326009245	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1104326009246	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1104326009247	active site
1104326009248	Na/Ca binding site [ion binding]; other site
1104326009249	catalytic site [active]
1104326009250	lipoprotein; Provisional; Region: PRK10397
1104326009251	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1104326009252	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1104326009253	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1104326009254	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1104326009255	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1104326009256	FliG C-terminal domain; Region: FliG_C; pfam01706
1104326009257	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1104326009258	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
1104326009259	Flagellar assembly protein FliH; Region: FliH; pfam02108
1104326009260	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1104326009261	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1104326009262	Walker A motif/ATP binding site; other site
1104326009263	Walker B motif; other site
1104326009264	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1104326009265	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1104326009266	flagellar hook-length control protein; Provisional; Region: PRK10118
1104326009267	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1104326009268	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1104326009269	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1104326009270	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1104326009271	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1104326009272	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1104326009273	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1104326009274	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1104326009275	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1104326009276	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1104326009277	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326009278	DNA binding residues [nucleotide binding]
1104326009279	dimerization interface [polypeptide binding]; other site
1104326009280	hypothetical protein; Provisional; Region: PRK10708
1104326009281	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1104326009282	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1104326009283	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326009284	active site
1104326009285	motif I; other site
1104326009286	motif II; other site
1104326009287	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1104326009288	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326009289	metal binding site [ion binding]; metal-binding site
1104326009290	active site
1104326009291	I-site; other site
1104326009292	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
1104326009293	hypothetical protein; Provisional; Region: PRK10062
1104326009294	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1104326009295	EamA-like transporter family; Region: EamA; pfam00892
1104326009296	EamA-like transporter family; Region: EamA; pfam00892
1104326009297	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1104326009298	additional DNA contacts [nucleotide binding]; other site
1104326009299	mismatch recognition site; other site
1104326009300	active site
1104326009301	zinc binding site [ion binding]; other site
1104326009302	DNA intercalation site [nucleotide binding]; other site
1104326009303	DNA cytosine methylase; Provisional; Region: PRK10458
1104326009304	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1104326009305	cofactor binding site; other site
1104326009306	DNA binding site [nucleotide binding]
1104326009307	substrate interaction site [chemical binding]; other site
1104326009308	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1104326009309	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1104326009310	Zn2+ binding site [ion binding]; other site
1104326009311	Mg2+ binding site [ion binding]; other site
1104326009312	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326009313	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1104326009314	trimer interface [polypeptide binding]; other site
1104326009315	eyelet of channel; other site
1104326009316	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1104326009317	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1104326009318	putative active site [active]
1104326009319	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1104326009320	PAS domain; Region: PAS; smart00091
1104326009321	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326009322	ATP binding site [chemical binding]; other site
1104326009323	Mg2+ binding site [ion binding]; other site
1104326009324	G-X-G motif; other site
1104326009325	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1104326009326	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009327	active site
1104326009328	phosphorylation site [posttranslational modification]
1104326009329	intermolecular recognition site; other site
1104326009330	dimerization interface [polypeptide binding]; other site
1104326009331	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1104326009332	ApbE family; Region: ApbE; pfam02424
1104326009333	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1104326009334	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1104326009335	putative active site [active]
1104326009336	putative FMN binding site [chemical binding]; other site
1104326009337	putative substrate binding site [chemical binding]; other site
1104326009338	putative catalytic residue [active]
1104326009339	FMN-binding domain; Region: FMN_bind; cl01081
1104326009340	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
1104326009341	L-aspartate oxidase; Provisional; Region: PRK06175
1104326009342	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1104326009343	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1104326009344	transmembrane helices; other site
1104326009345	fumarate hydratase; Provisional; Region: PRK15389
1104326009346	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1104326009347	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1104326009348	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326009349	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326009350	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1104326009351	dimerization interface [polypeptide binding]; other site
1104326009352	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1104326009353	Beta-lactamase; Region: Beta-lactamase; pfam00144
1104326009354	citrate-proton symporter; Provisional; Region: PRK15075
1104326009355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326009356	putative substrate translocation pore; other site
1104326009357	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1104326009358	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1104326009359	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326009360	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326009361	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1104326009362	putative dimerization interface [polypeptide binding]; other site
1104326009363	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1104326009364	putative CheA interaction surface; other site
1104326009365	chemotaxis protein CheA; Provisional; Region: PRK10547
1104326009366	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1104326009367	putative binding surface; other site
1104326009368	active site
1104326009369	CheY binding; Region: CheY-binding; pfam09078
1104326009370	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1104326009371	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326009372	ATP binding site [chemical binding]; other site
1104326009373	Mg2+ binding site [ion binding]; other site
1104326009374	G-X-G motif; other site
1104326009375	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1104326009376	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1104326009377	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1104326009378	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326009379	ligand binding site [chemical binding]; other site
1104326009380	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1104326009381	flagellar motor protein MotA; Validated; Region: PRK09110
1104326009382	transcriptional activator FlhC; Provisional; Region: PRK12722
1104326009383	transcriptional activator FlhD; Provisional; Region: PRK02909
1104326009384	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1104326009385	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326009386	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1104326009387	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326009388	DNA binding residues [nucleotide binding]
1104326009389	methyl-accepting protein IV; Provisional; Region: PRK09793
1104326009390	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326009391	dimerization interface [polypeptide binding]; other site
1104326009392	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326009393	dimer interface [polypeptide binding]; other site
1104326009394	putative CheW interface [polypeptide binding]; other site
1104326009395	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1104326009396	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1104326009397	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1104326009398	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326009399	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1104326009400	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1104326009401	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1104326009402	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1104326009403	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1104326009404	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1104326009405	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1104326009406	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1104326009407	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326009408	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326009409	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
1104326009410	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1104326009411	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326009412	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1104326009413	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1104326009414	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1104326009415	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1104326009416	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1104326009417	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1104326009418	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1104326009419	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1104326009420	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1104326009421	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1104326009422	SAF-like; Region: SAF_2; pfam13144
1104326009423	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1104326009424	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
1104326009425	FlgN protein; Region: FlgN; cl09176
1104326009426	Flagellar protein FliT; Region: FliT; cl05125
1104326009427	flagellar protein FliS; Validated; Region: fliS; PRK05685
1104326009428	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1104326009429	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1104326009430	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1104326009431	flagellin; Validated; Region: PRK08026
1104326009432	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1104326009433	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1104326009434	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1104326009435	Predicted membrane protein [Function unknown]; Region: COG2259
1104326009436	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1104326009437	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1104326009438	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1104326009439	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1104326009440	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
1104326009441	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
1104326009442	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1104326009443	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1104326009444	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1104326009445	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1104326009446	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1104326009447	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1104326009448	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1104326009449	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1104326009450	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1104326009451	Walker A motif/ATP binding site; other site
1104326009452	Walker B motif; other site
1104326009453	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1104326009454	Flagellar assembly protein FliH; Region: FliH; pfam02108
1104326009455	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1104326009456	FliG C-terminal domain; Region: FliG_C; pfam01706
1104326009457	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1104326009458	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1104326009459	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1104326009460	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
1104326009461	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1104326009462	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1104326009463	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1104326009464	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1104326009465	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009466	active site
1104326009467	phosphorylation site [posttranslational modification]
1104326009468	intermolecular recognition site; other site
1104326009469	dimerization interface [polypeptide binding]; other site
1104326009470	CheB methylesterase; Region: CheB_methylest; pfam01339
1104326009471	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1104326009472	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009473	active site
1104326009474	phosphorylation site [posttranslational modification]
1104326009475	intermolecular recognition site; other site
1104326009476	dimerization interface [polypeptide binding]; other site
1104326009477	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1104326009478	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1104326009479	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1104326009480	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1104326009481	FHIPEP family; Region: FHIPEP; pfam00771
1104326009482	Flagellar protein FlhE; Region: FlhE; pfam06366
1104326009483	Protein of unknown function (DUF1305); Region: DUF1305; cl01404
1104326009484	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1104326009485	Chorismate mutase type II; Region: CM_2; cl00693
1104326009486	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1104326009487	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326009488	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326009489	putative substrate translocation pore; other site
1104326009490	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1104326009491	IucA / IucC family; Region: IucA_IucC; pfam04183
1104326009492	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1104326009493	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1104326009494	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
1104326009495	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1104326009496	IucA / IucC family; Region: IucA_IucC; pfam04183
1104326009497	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1104326009498	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1104326009499	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326009500	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1104326009501	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326009502	N-terminal plug; other site
1104326009503	ligand-binding site [chemical binding]; other site
1104326009504	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1104326009505	homotrimer interaction site [polypeptide binding]; other site
1104326009506	putative active site [active]
1104326009507	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326009508	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326009509	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1104326009510	putative effector binding pocket; other site
1104326009511	putative dimerization interface [polypeptide binding]; other site
1104326009512	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1104326009513	non-specific DNA binding site [nucleotide binding]; other site
1104326009514	salt bridge; other site
1104326009515	sequence-specific DNA binding site [nucleotide binding]; other site
1104326009516	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1104326009517	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326009518	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
1104326009519	N-terminal domain interface [polypeptide binding]; other site
1104326009520	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1104326009521	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
1104326009522	putative substrate binding site [chemical binding]; other site
1104326009523	dimerization interface [polypeptide binding]; other site
1104326009524	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1104326009525	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326009526	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1104326009527	putative dimerization interface [polypeptide binding]; other site
1104326009528	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1104326009529	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1104326009530	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1104326009531	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1104326009532	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1104326009533	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326009534	motif II; other site
1104326009535	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1104326009536	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326009537	Ligand Binding Site [chemical binding]; other site
1104326009538	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1104326009539	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326009540	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1104326009541	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326009542	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1104326009543	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1104326009544	shikimate transporter; Provisional; Region: PRK09952
1104326009545	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326009546	putative substrate translocation pore; other site
1104326009547	AMP nucleosidase; Provisional; Region: PRK08292
1104326009548	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1104326009549	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1104326009550	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1104326009551	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1104326009552	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1104326009553	active site
1104326009554	MATE family multidrug exporter; Provisional; Region: PRK10189
1104326009555	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1104326009556	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1104326009557	putative active site pocket [active]
1104326009558	dimerization interface [polypeptide binding]; other site
1104326009559	putative catalytic residue [active]
1104326009560	hypothetical protein; Provisional; Region: PRK05423
1104326009561	Predicted membrane protein [Function unknown]; Region: COG1289
1104326009562	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1104326009563	DNA gyrase inhibitor; Provisional; Region: PRK10016
1104326009564	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1104326009565	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1104326009566	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1104326009567	exonuclease I; Provisional; Region: sbcB; PRK11779
1104326009568	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1104326009569	active site
1104326009570	catalytic site [active]
1104326009571	substrate binding site [chemical binding]; other site
1104326009572	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1104326009573	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1104326009574	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326009575	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1104326009576	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326009577	dimerization interface [polypeptide binding]; other site
1104326009578	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1104326009579	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1104326009580	putative NAD(P) binding site [chemical binding]; other site
1104326009581	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1104326009582	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1104326009583	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1104326009584	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1104326009585	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1104326009586	NAD binding site [chemical binding]; other site
1104326009587	dimerization interface [polypeptide binding]; other site
1104326009588	product binding site; other site
1104326009589	substrate binding site [chemical binding]; other site
1104326009590	zinc binding site [ion binding]; other site
1104326009591	catalytic residues [active]
1104326009592	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1104326009593	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326009594	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326009595	homodimer interface [polypeptide binding]; other site
1104326009596	catalytic residue [active]
1104326009597	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1104326009598	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326009599	active site
1104326009600	motif I; other site
1104326009601	motif II; other site
1104326009602	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1104326009603	putative active site pocket [active]
1104326009604	4-fold oligomerization interface [polypeptide binding]; other site
1104326009605	metal binding residues [ion binding]; metal-binding site
1104326009606	3-fold/trimer interface [polypeptide binding]; other site
1104326009607	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1104326009608	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1104326009609	putative active site [active]
1104326009610	oxyanion strand; other site
1104326009611	catalytic triad [active]
1104326009612	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1104326009613	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1104326009614	catalytic residues [active]
1104326009615	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1104326009616	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1104326009617	substrate binding site [chemical binding]; other site
1104326009618	glutamase interaction surface [polypeptide binding]; other site
1104326009619	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1104326009620	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1104326009621	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1104326009622	metal binding site [ion binding]; metal-binding site
1104326009623	chain length determinant protein WzzB; Provisional; Region: PRK15471
1104326009624	Chain length determinant protein; Region: Wzz; pfam02706
1104326009625	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1104326009626	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1104326009627	putative NAD(P) binding site [chemical binding]; other site
1104326009628	active site
1104326009629	putative substrate binding site [chemical binding]; other site
1104326009630	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1104326009631	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1104326009632	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1104326009633	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1104326009634	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1104326009635	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1104326009636	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1104326009637	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1104326009638	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1104326009639	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1104326009640	putative ADP-binding pocket [chemical binding]; other site
1104326009641	RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526
1104326009642	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
1104326009643	Ligand binding site; other site
1104326009644	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1104326009645	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1104326009646	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1104326009647	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1104326009648	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1104326009649	substrate binding site; other site
1104326009650	tetramer interface; other site
1104326009651	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1104326009652	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1104326009653	NADP binding site [chemical binding]; other site
1104326009654	active site
1104326009655	putative substrate binding site [chemical binding]; other site
1104326009656	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1104326009657	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1104326009658	NAD binding site [chemical binding]; other site
1104326009659	substrate binding site [chemical binding]; other site
1104326009660	homodimer interface [polypeptide binding]; other site
1104326009661	active site
1104326009662	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1104326009663	active site
1104326009664	tetramer interface; other site
1104326009665	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
1104326009666	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1104326009667	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1104326009668	putative ADP-binding pocket [chemical binding]; other site
1104326009669	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
1104326009670	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1104326009671	colanic acid exporter; Provisional; Region: PRK10459
1104326009672	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1104326009673	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1104326009674	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1104326009675	phosphomannomutase CpsG; Provisional; Region: PRK15414
1104326009676	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1104326009677	active site
1104326009678	substrate binding site [chemical binding]; other site
1104326009679	metal binding site [ion binding]; metal-binding site
1104326009680	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1104326009681	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1104326009682	Substrate binding site; other site
1104326009683	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1104326009684	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1104326009685	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1104326009686	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1104326009687	active site
1104326009688	GDP-Mannose binding site [chemical binding]; other site
1104326009689	dimer interface [polypeptide binding]; other site
1104326009690	modified nudix motif
1104326009691	metal binding site [ion binding]; metal-binding site
1104326009692	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1104326009693	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1104326009694	NADP binding site [chemical binding]; other site
1104326009695	active site
1104326009696	putative substrate binding site [chemical binding]; other site
1104326009697	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1104326009698	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1104326009699	NADP-binding site; other site
1104326009700	homotetramer interface [polypeptide binding]; other site
1104326009701	substrate binding site [chemical binding]; other site
1104326009702	homodimer interface [polypeptide binding]; other site
1104326009703	active site
1104326009704	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1104326009705	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1104326009706	putative trimer interface [polypeptide binding]; other site
1104326009707	putative active site [active]
1104326009708	putative substrate binding site [chemical binding]; other site
1104326009709	putative CoA binding site [chemical binding]; other site
1104326009710	putative glycosyl transferase; Provisional; Region: PRK10063
1104326009711	colanic acid biosynthesis glycosyl transferase WcaE; Region: wcaE; TIGR04009
1104326009712	active site
1104326009713	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
1104326009714	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1104326009715	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1104326009716	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1104326009717	putative acyl transferase; Provisional; Region: PRK10191
1104326009718	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1104326009719	trimer interface [polypeptide binding]; other site
1104326009720	active site
1104326009721	substrate binding site [chemical binding]; other site
1104326009722	CoA binding site [chemical binding]; other site
1104326009723	putative glycosyl transferase; Provisional; Region: PRK10018
1104326009724	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1104326009725	active site
1104326009726	tyrosine kinase; Provisional; Region: PRK11519
1104326009727	Chain length determinant protein; Region: Wzz; pfam02706
1104326009728	Chain length determinant protein; Region: Wzz; cl15801
1104326009729	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1104326009730	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1104326009731	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1104326009732	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1104326009733	active site
1104326009734	polysaccharide export protein Wza; Provisional; Region: PRK15078
1104326009735	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1104326009736	SLBB domain; Region: SLBB; pfam10531
1104326009737	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1104326009738	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1104326009739	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1104326009740	Transporter associated domain; Region: CorC_HlyC; smart01091
1104326009741	putative assembly protein; Provisional; Region: PRK10833
1104326009742	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1104326009743	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1104326009744	trimer interface [polypeptide binding]; other site
1104326009745	active site
1104326009746	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1104326009747	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1104326009748	ATP-binding site [chemical binding]; other site
1104326009749	Sugar specificity; other site
1104326009750	Pyrimidine base specificity; other site
1104326009751	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1104326009752	putative diguanylate cyclase; Provisional; Region: PRK09776
1104326009753	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326009754	putative active site [active]
1104326009755	heme pocket [chemical binding]; other site
1104326009756	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326009757	putative active site [active]
1104326009758	heme pocket [chemical binding]; other site
1104326009759	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326009760	putative active site [active]
1104326009761	heme pocket [chemical binding]; other site
1104326009762	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326009763	metal binding site [ion binding]; metal-binding site
1104326009764	active site
1104326009765	I-site; other site
1104326009766	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1104326009767	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1104326009768	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1104326009769	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1104326009770	minor groove reading motif; other site
1104326009771	helix-hairpin-helix signature motif; other site
1104326009772	substrate binding pocket [chemical binding]; other site
1104326009773	active site
1104326009774	putative chaperone; Provisional; Region: PRK11678
1104326009775	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1104326009776	nucleotide binding site [chemical binding]; other site
1104326009777	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1104326009778	SBD interface [polypeptide binding]; other site
1104326009779	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1104326009780	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326009781	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326009782	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1104326009783	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326009784	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1104326009785	putative transporter; Provisional; Region: PRK10504
1104326009786	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326009787	putative substrate translocation pore; other site
1104326009788	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1104326009789	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326009790	dimerization interface [polypeptide binding]; other site
1104326009791	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326009792	dimer interface [polypeptide binding]; other site
1104326009793	phosphorylation site [posttranslational modification]
1104326009794	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326009795	ATP binding site [chemical binding]; other site
1104326009796	Mg2+ binding site [ion binding]; other site
1104326009797	G-X-G motif; other site
1104326009798	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1104326009799	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009800	active site
1104326009801	phosphorylation site [posttranslational modification]
1104326009802	intermolecular recognition site; other site
1104326009803	dimerization interface [polypeptide binding]; other site
1104326009804	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326009805	DNA binding site [nucleotide binding]
1104326009806	Uncharacterized conserved protein [Function unknown]; Region: COG3422
1104326009807	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1104326009808	putative protease; Provisional; Region: PRK15452
1104326009809	Peptidase family U32; Region: Peptidase_U32; pfam01136
1104326009810	lipid kinase; Reviewed; Region: PRK13054
1104326009811	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1104326009812	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1104326009813	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1104326009814	putative active site; other site
1104326009815	catalytic residue [active]
1104326009816	nucleoside transporter; Region: 2A0110; TIGR00889
1104326009817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326009818	putative substrate translocation pore; other site
1104326009819	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1104326009820	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1104326009821	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326009822	substrate binding site [chemical binding]; other site
1104326009823	ATP binding site [chemical binding]; other site
1104326009824	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1104326009825	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326009826	DNA-binding site [nucleotide binding]; DNA binding site
1104326009827	UTRA domain; Region: UTRA; pfam07702
1104326009828	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1104326009829	dimer interface [polypeptide binding]; other site
1104326009830	substrate binding site [chemical binding]; other site
1104326009831	ATP binding site [chemical binding]; other site
1104326009832	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1104326009833	substrate binding site [chemical binding]; other site
1104326009834	multimerization interface [polypeptide binding]; other site
1104326009835	ATP binding site [chemical binding]; other site
1104326009836	YadA-like C-terminal region; Region: YadA; pfam03895
1104326009837	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
1104326009838	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326009839	inhibitor-cofactor binding pocket; inhibition site
1104326009840	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326009841	catalytic residue [active]
1104326009842	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1104326009843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326009844	catalytic residue [active]
1104326009845	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1104326009846	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1104326009847	catalytic residues [active]
1104326009848	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326009849	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326009850	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1104326009851	dimerization interface [polypeptide binding]; other site
1104326009852	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1104326009853	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1104326009854	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1104326009855	active site
1104326009856	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1104326009857	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1104326009858	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
1104326009859	Chain length determinant protein; Region: Wzz; pfam02706
1104326009860	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1104326009861	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1104326009862	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1104326009863	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1104326009864	active site
1104326009865	polysaccharide export protein Wza; Provisional; Region: PRK15078
1104326009866	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1104326009867	SLBB domain; Region: SLBB; pfam10531
1104326009868	SLBB domain; Region: SLBB; pfam10531
1104326009869	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1104326009870	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1104326009871	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326009872	Coenzyme A binding pocket [chemical binding]; other site
1104326009873	antiporter inner membrane protein; Provisional; Region: PRK11670
1104326009874	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1104326009875	Walker A motif; other site
1104326009876	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1104326009877	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1104326009878	active site
1104326009879	HIGH motif; other site
1104326009880	KMSKS motif; other site
1104326009881	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1104326009882	tRNA binding surface [nucleotide binding]; other site
1104326009883	anticodon binding site; other site
1104326009884	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1104326009885	dimer interface [polypeptide binding]; other site
1104326009886	putative tRNA-binding site [nucleotide binding]; other site
1104326009887	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1104326009888	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1104326009889	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1104326009890	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1104326009891	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326009892	active site
1104326009893	phosphorylation site [posttranslational modification]
1104326009894	intermolecular recognition site; other site
1104326009895	dimerization interface [polypeptide binding]; other site
1104326009896	LytTr DNA-binding domain; Region: LytTR; pfam04397
1104326009897	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1104326009898	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1104326009899	GAF domain; Region: GAF; pfam01590
1104326009900	Histidine kinase; Region: His_kinase; pfam06580
1104326009901	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326009902	ATP binding site [chemical binding]; other site
1104326009903	Mg2+ binding site [ion binding]; other site
1104326009904	G-X-G motif; other site
1104326009905	transcriptional regulator MirA; Provisional; Region: PRK15043
1104326009906	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1104326009907	DNA binding residues [nucleotide binding]
1104326009908	hypothetical protein; Provisional; Region: PRK13681
1104326009909	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326009910	putative PBP binding loops; other site
1104326009911	ABC-ATPase subunit interface; other site
1104326009912	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1104326009913	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1104326009914	Walker A/P-loop; other site
1104326009915	ATP binding site [chemical binding]; other site
1104326009916	Q-loop/lid; other site
1104326009917	ABC transporter signature motif; other site
1104326009918	Walker B; other site
1104326009919	D-loop; other site
1104326009920	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1104326009921	H-loop/switch region; other site
1104326009922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326009923	dimer interface [polypeptide binding]; other site
1104326009924	conserved gate region; other site
1104326009925	ABC-ATPase subunit interface; other site
1104326009926	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1104326009927	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1104326009928	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1104326009929	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1104326009930	D-lactate dehydrogenase; Provisional; Region: PRK11183
1104326009931	FAD binding domain; Region: FAD_binding_4; pfam01565
1104326009932	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1104326009933	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1104326009934	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326009935	Coenzyme A binding pocket [chemical binding]; other site
1104326009936	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1104326009937	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1104326009938	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1104326009939	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1104326009940	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1104326009941	oxidoreductase; Provisional; Region: PRK12743
1104326009942	classical (c) SDRs; Region: SDR_c; cd05233
1104326009943	NAD(P) binding site [chemical binding]; other site
1104326009944	active site
1104326009945	Outer membrane efflux protein; Region: OEP; pfam02321
1104326009946	Outer membrane efflux protein; Region: OEP; pfam02321
1104326009947	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1104326009948	beta-galactosidase; Region: BGL; TIGR03356
1104326009949	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1104326009950	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326009951	active site turn [active]
1104326009952	phosphorylation site [posttranslational modification]
1104326009953	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326009954	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1104326009955	HPr interaction site; other site
1104326009956	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1104326009957	active site
1104326009958	phosphorylation site [posttranslational modification]
1104326009959	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1104326009960	CAT RNA binding domain; Region: CAT_RBD; smart01061
1104326009961	PRD domain; Region: PRD; pfam00874
1104326009962	PRD domain; Region: PRD; pfam00874
1104326009963	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
1104326009964	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1104326009965	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1104326009966	FMN binding site [chemical binding]; other site
1104326009967	active site
1104326009968	catalytic residues [active]
1104326009969	substrate binding site [chemical binding]; other site
1104326009970	hypothetical protein; Provisional; Region: PRK01821
1104326009971	hypothetical protein; Provisional; Region: PRK10711
1104326009972	cytidine deaminase; Provisional; Region: PRK09027
1104326009973	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1104326009974	active site
1104326009975	catalytic motif [active]
1104326009976	Zn binding site [ion binding]; other site
1104326009977	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1104326009978	active site
1104326009979	catalytic motif [active]
1104326009980	Zn binding site [ion binding]; other site
1104326009981	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1104326009982	putative active site [active]
1104326009983	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1104326009984	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1104326009985	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326009986	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326009987	TM-ABC transporter signature motif; other site
1104326009988	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326009989	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1104326009990	Walker A/P-loop; other site
1104326009991	ATP binding site [chemical binding]; other site
1104326009992	Q-loop/lid; other site
1104326009993	ABC transporter signature motif; other site
1104326009994	Walker B; other site
1104326009995	D-loop; other site
1104326009996	H-loop/switch region; other site
1104326009997	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326009998	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1104326009999	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1104326010000	ligand binding site [chemical binding]; other site
1104326010001	calcium binding site [ion binding]; other site
1104326010002	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1104326010003	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326010004	DNA binding site [nucleotide binding]
1104326010005	domain linker motif; other site
1104326010006	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1104326010007	ligand binding site [chemical binding]; other site
1104326010008	dimerization interface (closed form) [polypeptide binding]; other site
1104326010009	Predicted membrane protein [Function unknown]; Region: COG2311
1104326010010	hypothetical protein; Provisional; Region: PRK10835
1104326010011	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1104326010012	GTP cyclohydrolase I; Provisional; Region: PLN03044
1104326010013	active site
1104326010014	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1104326010015	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1104326010016	S-formylglutathione hydrolase; Region: PLN02442
1104326010017	putative outer membrane receptor; Provisional; Region: PRK13513
1104326010018	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326010019	N-terminal plug; other site
1104326010020	ligand-binding site [chemical binding]; other site
1104326010021	lysine transporter; Provisional; Region: PRK10836
1104326010022	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1104326010023	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326010024	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1104326010025	putative dimerization interface [polypeptide binding]; other site
1104326010026	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1104326010027	endonuclease IV; Provisional; Region: PRK01060
1104326010028	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1104326010029	DNA interaction; other site
1104326010030	Metal-binding active site; metal-binding site
1104326010031	AP (apurinic/apyrimidinic) site pocket; other site
1104326010032	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1104326010033	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1104326010034	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1104326010035	active site
1104326010036	P-loop; other site
1104326010037	phosphorylation site [posttranslational modification]
1104326010038	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1104326010039	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1104326010040	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1104326010041	putative substrate binding site [chemical binding]; other site
1104326010042	putative ATP binding site [chemical binding]; other site
1104326010043	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1104326010044	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1104326010045	active site
1104326010046	phosphorylation site [posttranslational modification]
1104326010047	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1104326010048	dimerization domain swap beta strand [polypeptide binding]; other site
1104326010049	regulatory protein interface [polypeptide binding]; other site
1104326010050	active site
1104326010051	regulatory phosphorylation site [posttranslational modification]; other site
1104326010052	sugar efflux transporter B; Provisional; Region: PRK15011
1104326010053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010054	putative substrate translocation pore; other site
1104326010055	Flagellin N-methylase; Region: FliB; pfam03692
1104326010056	elongation factor P; Provisional; Region: PRK04542
1104326010057	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1104326010058	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1104326010059	RNA binding site [nucleotide binding]; other site
1104326010060	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1104326010061	RNA binding site [nucleotide binding]; other site
1104326010062	mannonate dehydratase; Provisional; Region: PRK03906
1104326010063	mannonate dehydratase; Region: uxuA; TIGR00695
1104326010064	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1104326010065	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1104326010066	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1104326010067	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1104326010068	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1104326010069	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; cl08458
1104326010070	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1104326010071	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1104326010072	active site
1104326010073	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1104326010074	NlpC/P60 family; Region: NLPC_P60; pfam00877
1104326010075	phage resistance protein; Provisional; Region: PRK10551
1104326010076	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1104326010077	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326010078	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1104326010079	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1104326010080	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1104326010081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326010082	dimer interface [polypeptide binding]; other site
1104326010083	conserved gate region; other site
1104326010084	putative PBP binding loops; other site
1104326010085	ABC-ATPase subunit interface; other site
1104326010086	microcin C ABC transporter permease; Provisional; Region: PRK15021
1104326010087	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326010088	dimer interface [polypeptide binding]; other site
1104326010089	conserved gate region; other site
1104326010090	ABC-ATPase subunit interface; other site
1104326010091	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1104326010092	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326010093	Walker A/P-loop; other site
1104326010094	ATP binding site [chemical binding]; other site
1104326010095	Q-loop/lid; other site
1104326010096	ABC transporter signature motif; other site
1104326010097	Walker B; other site
1104326010098	D-loop; other site
1104326010099	H-loop/switch region; other site
1104326010100	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1104326010101	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1104326010102	Walker A/P-loop; other site
1104326010103	ATP binding site [chemical binding]; other site
1104326010104	Q-loop/lid; other site
1104326010105	ABC transporter signature motif; other site
1104326010106	Walker B; other site
1104326010107	D-loop; other site
1104326010108	H-loop/switch region; other site
1104326010109	hypothetical protein; Provisional; Region: PRK11835
1104326010110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010111	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1104326010112	putative substrate translocation pore; other site
1104326010113	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1104326010114	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326010115	RNA binding surface [nucleotide binding]; other site
1104326010116	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1104326010117	active site
1104326010118	uracil binding [chemical binding]; other site
1104326010119	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1104326010120	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326010121	ATP binding site [chemical binding]; other site
1104326010122	putative Mg++ binding site [ion binding]; other site
1104326010123	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326010124	nucleotide binding region [chemical binding]; other site
1104326010125	ATP-binding site [chemical binding]; other site
1104326010126	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326010127	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326010128	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1104326010129	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1104326010130	5S rRNA interface [nucleotide binding]; other site
1104326010131	CTC domain interface [polypeptide binding]; other site
1104326010132	L16 interface [polypeptide binding]; other site
1104326010133	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1104326010134	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1104326010135	hypothetical protein; Provisional; Region: PRK13689
1104326010136	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1104326010137	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1104326010138	Sulfatase; Region: Sulfatase; cl17466
1104326010139	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010140	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326010141	putative substrate translocation pore; other site
1104326010142	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1104326010143	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1104326010144	secondary substrate binding site; other site
1104326010145	primary substrate binding site; other site
1104326010146	inhibition loop; other site
1104326010147	dimerization interface [polypeptide binding]; other site
1104326010148	malate:quinone oxidoreductase; Validated; Region: PRK05257
1104326010149	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1104326010150	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1104326010151	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1104326010152	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1104326010153	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1104326010154	MgtE intracellular N domain; Region: MgtE_N; smart00924
1104326010155	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1104326010156	Divalent cation transporter; Region: MgtE; cl00786
1104326010157	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1104326010158	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1104326010159	Walker A/P-loop; other site
1104326010160	ATP binding site [chemical binding]; other site
1104326010161	Q-loop/lid; other site
1104326010162	ABC transporter signature motif; other site
1104326010163	Walker B; other site
1104326010164	D-loop; other site
1104326010165	H-loop/switch region; other site
1104326010166	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1104326010167	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1104326010168	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1104326010169	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326010170	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326010171	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1104326010172	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1104326010173	DNA binding site [nucleotide binding]
1104326010174	active site
1104326010175	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1104326010176	ApbE family; Region: ApbE; pfam02424
1104326010177	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1104326010178	outer membrane porin protein C; Provisional; Region: PRK10554
1104326010179	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1104326010180	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326010181	ATP binding site [chemical binding]; other site
1104326010182	Mg2+ binding site [ion binding]; other site
1104326010183	G-X-G motif; other site
1104326010184	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1104326010185	putative binding surface; other site
1104326010186	active site
1104326010187	transcriptional regulator RcsB; Provisional; Region: PRK10840
1104326010188	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326010189	active site
1104326010190	phosphorylation site [posttranslational modification]
1104326010191	intermolecular recognition site; other site
1104326010192	dimerization interface [polypeptide binding]; other site
1104326010193	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326010194	DNA binding residues [nucleotide binding]
1104326010195	dimerization interface [polypeptide binding]; other site
1104326010196	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1104326010197	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326010198	dimer interface [polypeptide binding]; other site
1104326010199	phosphorylation site [posttranslational modification]
1104326010200	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326010201	ATP binding site [chemical binding]; other site
1104326010202	Mg2+ binding site [ion binding]; other site
1104326010203	G-X-G motif; other site
1104326010204	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1104326010205	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326010206	active site
1104326010207	phosphorylation site [posttranslational modification]
1104326010208	intermolecular recognition site; other site
1104326010209	dimerization interface [polypeptide binding]; other site
1104326010210	DNA gyrase subunit A; Validated; Region: PRK05560
1104326010211	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1104326010212	CAP-like domain; other site
1104326010213	active site
1104326010214	primary dimer interface [polypeptide binding]; other site
1104326010215	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326010216	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326010217	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326010218	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326010219	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326010220	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326010221	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1104326010222	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326010223	S-adenosylmethionine binding site [chemical binding]; other site
1104326010224	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1104326010225	ATP cone domain; Region: ATP-cone; pfam03477
1104326010226	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1104326010227	active site
1104326010228	dimer interface [polypeptide binding]; other site
1104326010229	catalytic residues [active]
1104326010230	effector binding site; other site
1104326010231	R2 peptide binding site; other site
1104326010232	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1104326010233	dimer interface [polypeptide binding]; other site
1104326010234	putative radical transfer pathway; other site
1104326010235	diiron center [ion binding]; other site
1104326010236	tyrosyl radical; other site
1104326010237	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1104326010238	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326010239	catalytic loop [active]
1104326010240	iron binding site [ion binding]; other site
1104326010241	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1104326010242	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1104326010243	active site
1104326010244	catalytic site [active]
1104326010245	metal binding site [ion binding]; metal-binding site
1104326010246	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1104326010247	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010248	putative substrate translocation pore; other site
1104326010249	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1104326010250	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1104326010251	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1104326010252	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1104326010253	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1104326010254	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1104326010255	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1104326010256	Cysteine-rich domain; Region: CCG; pfam02754
1104326010257	Cysteine-rich domain; Region: CCG; pfam02754
1104326010258	hypothetical protein; Provisional; Region: PRK03673
1104326010259	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1104326010260	putative MPT binding site; other site
1104326010261	Competence-damaged protein; Region: CinA; cl00666
1104326010262	YfaZ precursor; Region: YfaZ; pfam07437
1104326010263	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1104326010264	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1104326010265	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326010266	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326010267	dimer interface [polypeptide binding]; other site
1104326010268	phosphorylation site [posttranslational modification]
1104326010269	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326010270	ATP binding site [chemical binding]; other site
1104326010271	Mg2+ binding site [ion binding]; other site
1104326010272	G-X-G motif; other site
1104326010273	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1104326010274	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326010275	active site
1104326010276	phosphorylation site [posttranslational modification]
1104326010277	intermolecular recognition site; other site
1104326010278	dimerization interface [polypeptide binding]; other site
1104326010279	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326010280	DNA binding site [nucleotide binding]
1104326010281	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
1104326010282	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1104326010283	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1104326010284	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1104326010285	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1104326010286	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1104326010287	acyl-activating enzyme (AAE) consensus motif; other site
1104326010288	putative AMP binding site [chemical binding]; other site
1104326010289	putative active site [active]
1104326010290	putative CoA binding site [chemical binding]; other site
1104326010291	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1104326010292	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1104326010293	active site
1104326010294	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1104326010295	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1104326010296	substrate binding site [chemical binding]; other site
1104326010297	oxyanion hole (OAH) forming residues; other site
1104326010298	trimer interface [polypeptide binding]; other site
1104326010299	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1104326010300	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1104326010301	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1104326010302	dimer interface [polypeptide binding]; other site
1104326010303	tetramer interface [polypeptide binding]; other site
1104326010304	PYR/PP interface [polypeptide binding]; other site
1104326010305	TPP binding site [chemical binding]; other site
1104326010306	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1104326010307	TPP-binding site; other site
1104326010308	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1104326010309	isochorismate synthases; Region: isochor_syn; TIGR00543
1104326010310	hypothetical protein; Provisional; Region: PRK10404
1104326010311	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326010312	Coenzyme A binding pocket [chemical binding]; other site
1104326010313	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1104326010314	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1104326010315	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1104326010316	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326010317	active site
1104326010318	phosphorylation site [posttranslational modification]
1104326010319	intermolecular recognition site; other site
1104326010320	dimerization interface [polypeptide binding]; other site
1104326010321	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1104326010322	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1104326010323	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1104326010324	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1104326010325	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1104326010326	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1104326010327	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1104326010328	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1104326010329	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1104326010330	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1104326010331	4Fe-4S binding domain; Region: Fer4; pfam00037
1104326010332	4Fe-4S binding domain; Region: Fer4; pfam00037
1104326010333	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1104326010334	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1104326010335	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326010336	catalytic loop [active]
1104326010337	iron binding site [ion binding]; other site
1104326010338	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1104326010339	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1104326010340	[4Fe-4S] binding site [ion binding]; other site
1104326010341	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1104326010342	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1104326010343	SLBB domain; Region: SLBB; pfam10531
1104326010344	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1104326010345	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1104326010346	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1104326010347	putative dimer interface [polypeptide binding]; other site
1104326010348	[2Fe-2S] cluster binding site [ion binding]; other site
1104326010349	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1104326010350	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1104326010351	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1104326010352	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1104326010353	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1104326010354	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1104326010355	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326010356	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1104326010357	putative dimerization interface [polypeptide binding]; other site
1104326010358	aminotransferase AlaT; Validated; Region: PRK09265
1104326010359	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326010360	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326010361	homodimer interface [polypeptide binding]; other site
1104326010362	catalytic residue [active]
1104326010363	5'-nucleotidase; Provisional; Region: PRK03826
1104326010364	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1104326010365	transmembrane helices; other site
1104326010366	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1104326010367	TrkA-C domain; Region: TrkA_C; pfam02080
1104326010368	TrkA-C domain; Region: TrkA_C; pfam02080
1104326010369	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1104326010370	putative phosphatase; Provisional; Region: PRK11587
1104326010371	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326010372	motif II; other site
1104326010373	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1104326010374	hypothetical protein; Validated; Region: PRK05445
1104326010375	hypothetical protein; Provisional; Region: PRK01816
1104326010376	propionate/acetate kinase; Provisional; Region: PRK12379
1104326010377	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1104326010378	phosphate acetyltransferase; Reviewed; Region: PRK05632
1104326010379	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1104326010380	DRTGG domain; Region: DRTGG; pfam07085
1104326010381	phosphate acetyltransferase; Region: pta; TIGR00651
1104326010382	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1104326010383	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1104326010384	PYR/PP interface [polypeptide binding]; other site
1104326010385	dimer interface [polypeptide binding]; other site
1104326010386	TPP binding site [chemical binding]; other site
1104326010387	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1104326010388	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1104326010389	TPP-binding site [chemical binding]; other site
1104326010390	dimer interface [polypeptide binding]; other site
1104326010391	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1104326010392	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1104326010393	active site
1104326010394	P-loop; other site
1104326010395	phosphorylation site [posttranslational modification]
1104326010396	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1104326010397	active site
1104326010398	phosphorylation site [posttranslational modification]
1104326010399	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326010400	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326010401	DNA binding site [nucleotide binding]
1104326010402	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1104326010403	putative dimerization interface [polypeptide binding]; other site
1104326010404	putative ligand binding site [chemical binding]; other site
1104326010405	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1104326010406	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1104326010407	nudix motif; other site
1104326010408	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1104326010409	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1104326010410	active site
1104326010411	metal binding site [ion binding]; metal-binding site
1104326010412	homotetramer interface [polypeptide binding]; other site
1104326010413	glutathione S-transferase; Provisional; Region: PRK15113
1104326010414	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1104326010415	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1104326010416	N-terminal domain interface [polypeptide binding]; other site
1104326010417	putative dimer interface [polypeptide binding]; other site
1104326010418	putative substrate binding pocket (H-site) [chemical binding]; other site
1104326010419	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1104326010420	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1104326010421	C-terminal domain interface [polypeptide binding]; other site
1104326010422	GSH binding site (G-site) [chemical binding]; other site
1104326010423	dimer interface [polypeptide binding]; other site
1104326010424	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1104326010425	N-terminal domain interface [polypeptide binding]; other site
1104326010426	putative dimer interface [polypeptide binding]; other site
1104326010427	active site
1104326010428	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1104326010429	homooctamer interface [polypeptide binding]; other site
1104326010430	active site
1104326010431	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1104326010432	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1104326010433	putative NAD(P) binding site [chemical binding]; other site
1104326010434	putative active site [active]
1104326010435	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1104326010436	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326010437	Coenzyme A binding pocket [chemical binding]; other site
1104326010438	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1104326010439	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326010440	Walker A/P-loop; other site
1104326010441	ATP binding site [chemical binding]; other site
1104326010442	Q-loop/lid; other site
1104326010443	ABC transporter signature motif; other site
1104326010444	Walker B; other site
1104326010445	D-loop; other site
1104326010446	H-loop/switch region; other site
1104326010447	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326010448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326010449	dimer interface [polypeptide binding]; other site
1104326010450	conserved gate region; other site
1104326010451	putative PBP binding loops; other site
1104326010452	ABC-ATPase subunit interface; other site
1104326010453	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326010454	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326010455	dimer interface [polypeptide binding]; other site
1104326010456	conserved gate region; other site
1104326010457	putative PBP binding loops; other site
1104326010458	ABC-ATPase subunit interface; other site
1104326010459	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1104326010460	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326010461	substrate binding pocket [chemical binding]; other site
1104326010462	membrane-bound complex binding site; other site
1104326010463	hinge residues; other site
1104326010464	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1104326010465	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326010466	substrate binding pocket [chemical binding]; other site
1104326010467	membrane-bound complex binding site; other site
1104326010468	hinge residues; other site
1104326010469	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1104326010470	Flavoprotein; Region: Flavoprotein; pfam02441
1104326010471	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1104326010472	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1104326010473	active site
1104326010474	tetramer interface [polypeptide binding]; other site
1104326010475	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326010476	active site
1104326010477	colicin V production protein; Provisional; Region: PRK10845
1104326010478	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1104326010479	cell division protein DedD; Provisional; Region: PRK11633
1104326010480	Sporulation related domain; Region: SPOR; pfam05036
1104326010481	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1104326010482	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1104326010483	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1104326010484	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1104326010485	hypothetical protein; Provisional; Region: PRK10847
1104326010486	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1104326010487	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1104326010488	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1104326010489	dimerization interface 3.5A [polypeptide binding]; other site
1104326010490	active site
1104326010491	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1104326010492	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1104326010493	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1104326010494	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1104326010495	ligand binding site [chemical binding]; other site
1104326010496	NAD binding site [chemical binding]; other site
1104326010497	catalytic site [active]
1104326010498	homodimer interface [polypeptide binding]; other site
1104326010499	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1104326010500	putative transporter; Provisional; Region: PRK12382
1104326010501	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010502	putative substrate translocation pore; other site
1104326010503	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1104326010504	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1104326010505	dimer interface [polypeptide binding]; other site
1104326010506	active site
1104326010507	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1104326010508	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1104326010509	YfcL protein; Region: YfcL; pfam08891
1104326010510	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1104326010511	hypothetical protein; Provisional; Region: PRK10621
1104326010512	Predicted permeases [General function prediction only]; Region: COG0730
1104326010513	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1104326010514	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1104326010515	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1104326010516	Tetramer interface [polypeptide binding]; other site
1104326010517	active site
1104326010518	FMN-binding site [chemical binding]; other site
1104326010519	HemK family putative methylases; Region: hemK_fam; TIGR00536
1104326010520	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326010521	S-adenosylmethionine binding site [chemical binding]; other site
1104326010522	hypothetical protein; Provisional; Region: PRK04946
1104326010523	Smr domain; Region: Smr; pfam01713
1104326010524	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1104326010525	catalytic core [active]
1104326010526	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1104326010527	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1104326010528	substrate binding site [chemical binding]; other site
1104326010529	oxyanion hole (OAH) forming residues; other site
1104326010530	trimer interface [polypeptide binding]; other site
1104326010531	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1104326010532	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1104326010533	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1104326010534	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1104326010535	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1104326010536	dimer interface [polypeptide binding]; other site
1104326010537	active site
1104326010538	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1104326010539	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1104326010540	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1104326010541	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1104326010542	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1104326010543	heme-binding site [chemical binding]; other site
1104326010544	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326010545	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326010546	metal binding site [ion binding]; metal-binding site
1104326010547	active site
1104326010548	I-site; other site
1104326010549	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1104326010550	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1104326010551	putative acyl-acceptor binding pocket; other site
1104326010552	aminotransferase; Validated; Region: PRK08175
1104326010553	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326010554	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326010555	homodimer interface [polypeptide binding]; other site
1104326010556	catalytic residue [active]
1104326010557	potential frameshift: common BLAST hit: gi|296104061|ref|YP_003614207.1| putative sensory kinase in two-component system
1104326010558	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1104326010559	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326010560	active site
1104326010561	phosphorylation site [posttranslational modification]
1104326010562	intermolecular recognition site; other site
1104326010563	dimerization interface [polypeptide binding]; other site
1104326010564	LytTr DNA-binding domain; Region: LytTR; pfam04397
1104326010565	glucokinase; Provisional; Region: glk; PRK00292
1104326010566	glucokinase, proteobacterial type; Region: glk; TIGR00749
1104326010567	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1104326010568	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1104326010569	Cl- selectivity filter; other site
1104326010570	Cl- binding residues [ion binding]; other site
1104326010571	pore gating glutamate residue; other site
1104326010572	dimer interface [polypeptide binding]; other site
1104326010573	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1104326010574	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1104326010575	dimer interface [polypeptide binding]; other site
1104326010576	PYR/PP interface [polypeptide binding]; other site
1104326010577	TPP binding site [chemical binding]; other site
1104326010578	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326010579	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1104326010580	TPP-binding site [chemical binding]; other site
1104326010581	dimer interface [polypeptide binding]; other site
1104326010582	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326010583	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326010584	active site
1104326010585	catalytic tetrad [active]
1104326010586	manganese transport protein MntH; Reviewed; Region: PRK00701
1104326010587	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1104326010588	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1104326010589	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1104326010590	Nucleoside recognition; Region: Gate; pfam07670
1104326010591	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1104326010592	MASE1; Region: MASE1; pfam05231
1104326010593	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326010594	diguanylate cyclase; Region: GGDEF; smart00267
1104326010595	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326010596	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1104326010597	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1104326010598	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1104326010599	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1104326010600	active site
1104326010601	HIGH motif; other site
1104326010602	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1104326010603	active site
1104326010604	KMSKS motif; other site
1104326010605	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1104326010606	HD domain; Region: HD_4; pfam13328
1104326010607	Membrane transport protein; Region: Mem_trans; cl09117
1104326010608	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1104326010609	domain interfaces; other site
1104326010610	active site
1104326010611	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326010612	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326010613	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1104326010614	putative dimerization interface [polypeptide binding]; other site
1104326010615	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1104326010616	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1104326010617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1104326010618	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1104326010619	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1104326010620	nucleotide binding pocket [chemical binding]; other site
1104326010621	K-X-D-G motif; other site
1104326010622	catalytic site [active]
1104326010623	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1104326010624	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1104326010625	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
1104326010626	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1104326010627	Dimer interface [polypeptide binding]; other site
1104326010628	BRCT sequence motif; other site
1104326010629	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1104326010630	cell division protein ZipA; Provisional; Region: PRK03427
1104326010631	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1104326010632	FtsZ protein binding site [polypeptide binding]; other site
1104326010633	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1104326010634	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1104326010635	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1104326010636	dimer interface [polypeptide binding]; other site
1104326010637	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326010638	catalytic residue [active]
1104326010639	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1104326010640	dimerization domain swap beta strand [polypeptide binding]; other site
1104326010641	regulatory protein interface [polypeptide binding]; other site
1104326010642	active site
1104326010643	regulatory phosphorylation site [posttranslational modification]; other site
1104326010644	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1104326010645	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1104326010646	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1104326010647	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1104326010648	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1104326010649	HPr interaction site; other site
1104326010650	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1104326010651	active site
1104326010652	phosphorylation site [posttranslational modification]
1104326010653	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1104326010654	dimer interface [polypeptide binding]; other site
1104326010655	pyridoxamine kinase; Validated; Region: PRK05756
1104326010656	pyridoxal binding site [chemical binding]; other site
1104326010657	ATP binding site [chemical binding]; other site
1104326010658	cysteine synthase B; Region: cysM; TIGR01138
1104326010659	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1104326010660	dimer interface [polypeptide binding]; other site
1104326010661	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326010662	catalytic residue [active]
1104326010663	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1104326010664	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1104326010665	Walker A/P-loop; other site
1104326010666	ATP binding site [chemical binding]; other site
1104326010667	Q-loop/lid; other site
1104326010668	ABC transporter signature motif; other site
1104326010669	Walker B; other site
1104326010670	D-loop; other site
1104326010671	H-loop/switch region; other site
1104326010672	TOBE-like domain; Region: TOBE_3; pfam12857
1104326010673	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326010674	dimer interface [polypeptide binding]; other site
1104326010675	conserved gate region; other site
1104326010676	putative PBP binding loops; other site
1104326010677	ABC-ATPase subunit interface; other site
1104326010678	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1104326010679	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326010680	dimer interface [polypeptide binding]; other site
1104326010681	conserved gate region; other site
1104326010682	putative PBP binding loops; other site
1104326010683	ABC-ATPase subunit interface; other site
1104326010684	thiosulfate transporter subunit; Provisional; Region: PRK10852
1104326010685	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1104326010686	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1104326010687	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1104326010688	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1104326010689	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1104326010690	putative acetyltransferase; Provisional; Region: PRK03624
1104326010691	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326010692	Coenzyme A binding pocket [chemical binding]; other site
1104326010693	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1104326010694	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1104326010695	active site
1104326010696	metal binding site [ion binding]; metal-binding site
1104326010697	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1104326010698	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1104326010699	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1104326010700	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1104326010701	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1104326010702	putative NAD(P) binding site [chemical binding]; other site
1104326010703	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1104326010704	transaldolase-like protein; Provisional; Region: PTZ00411
1104326010705	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1104326010706	active site
1104326010707	dimer interface [polypeptide binding]; other site
1104326010708	catalytic residue [active]
1104326010709	transketolase; Reviewed; Region: PRK12753
1104326010710	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1104326010711	TPP-binding site [chemical binding]; other site
1104326010712	dimer interface [polypeptide binding]; other site
1104326010713	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1104326010714	PYR/PP interface [polypeptide binding]; other site
1104326010715	dimer interface [polypeptide binding]; other site
1104326010716	TPP binding site [chemical binding]; other site
1104326010717	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1104326010718	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1104326010719	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1104326010720	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1104326010721	dimer interface [polypeptide binding]; other site
1104326010722	ADP-ribose binding site [chemical binding]; other site
1104326010723	active site
1104326010724	nudix motif; other site
1104326010725	metal binding site [ion binding]; metal-binding site
1104326010726	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1104326010727	4Fe-4S binding domain; Region: Fer4; pfam00037
1104326010728	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1104326010729	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1104326010730	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326010731	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1104326010732	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1104326010733	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326010734	dimerization interface [polypeptide binding]; other site
1104326010735	Histidine kinase; Region: HisKA_3; pfam07730
1104326010736	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326010737	ATP binding site [chemical binding]; other site
1104326010738	Mg2+ binding site [ion binding]; other site
1104326010739	G-X-G motif; other site
1104326010740	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1104326010741	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326010742	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1104326010743	ArsC family; Region: ArsC; pfam03960
1104326010744	putative catalytic residues [active]
1104326010745	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1104326010746	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1104326010747	metal binding site [ion binding]; metal-binding site
1104326010748	dimer interface [polypeptide binding]; other site
1104326010749	hypothetical protein; Provisional; Region: PRK13664
1104326010750	putative hydrolase; Provisional; Region: PRK11460
1104326010751	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1104326010752	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1104326010753	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
1104326010754	Helicase; Region: Helicase_RecD; pfam05127
1104326010755	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1104326010756	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1104326010757	Predicted metalloprotease [General function prediction only]; Region: COG2321
1104326010758	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1104326010759	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1104326010760	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1104326010761	ATP binding site [chemical binding]; other site
1104326010762	active site
1104326010763	substrate binding site [chemical binding]; other site
1104326010764	lipoprotein; Provisional; Region: PRK11679
1104326010765	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1104326010766	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1104326010767	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1104326010768	dimer interface [polypeptide binding]; other site
1104326010769	active site
1104326010770	catalytic residue [active]
1104326010771	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1104326010772	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1104326010773	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1104326010774	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1104326010775	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1104326010776	catalytic triad [active]
1104326010777	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1104326010778	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1104326010779	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1104326010780	Peptidase family M48; Region: Peptidase_M48; cl12018
1104326010781	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1104326010782	ArsC family; Region: ArsC; pfam03960
1104326010783	catalytic residues [active]
1104326010784	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1104326010785	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1104326010786	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
1104326010787	active site
1104326010788	dimer interface [polypeptide binding]; other site
1104326010789	catalytic nucleophile [active]
1104326010790	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1104326010791	interface (dimer of trimers) [polypeptide binding]; other site
1104326010792	Substrate-binding/catalytic site; other site
1104326010793	Zn-binding sites [ion binding]; other site
1104326010794	DNA replication initiation factor; Provisional; Region: PRK08084
1104326010795	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1104326010796	uracil transporter; Provisional; Region: PRK10720
1104326010797	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326010798	active site
1104326010799	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
1104326010800	beta-galactosidase; Region: BGL; TIGR03356
1104326010801	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1104326010802	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1104326010803	nucleotide binding site [chemical binding]; other site
1104326010804	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1104326010805	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1104326010806	dimerization interface [polypeptide binding]; other site
1104326010807	putative ATP binding site [chemical binding]; other site
1104326010808	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1104326010809	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1104326010810	active site
1104326010811	substrate binding site [chemical binding]; other site
1104326010812	cosubstrate binding site; other site
1104326010813	catalytic site [active]
1104326010814	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1104326010815	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1104326010816	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1104326010817	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1104326010818	domain interface [polypeptide binding]; other site
1104326010819	active site
1104326010820	catalytic site [active]
1104326010821	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1104326010822	domain interface [polypeptide binding]; other site
1104326010823	active site
1104326010824	catalytic site [active]
1104326010825	exopolyphosphatase; Provisional; Region: PRK10854
1104326010826	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1104326010827	MASE1; Region: MASE1; pfam05231
1104326010828	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326010829	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1104326010830	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326010831	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1104326010832	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326010833	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326010834	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1104326010835	dimerization interface [polypeptide binding]; other site
1104326010836	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326010837	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010838	putative substrate translocation pore; other site
1104326010839	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326010840	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
1104326010841	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1104326010842	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326010843	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1104326010844	substrate binding site [chemical binding]; other site
1104326010845	ATP binding site [chemical binding]; other site
1104326010846	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
1104326010847	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
1104326010848	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326010849	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326010850	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326010851	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326010852	TM-ABC transporter signature motif; other site
1104326010853	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1104326010854	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326010855	Walker A/P-loop; other site
1104326010856	ATP binding site [chemical binding]; other site
1104326010857	Q-loop/lid; other site
1104326010858	ABC transporter signature motif; other site
1104326010859	Walker B; other site
1104326010860	D-loop; other site
1104326010861	H-loop/switch region; other site
1104326010862	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326010863	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1104326010864	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1104326010865	ligand binding site [chemical binding]; other site
1104326010866	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326010867	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326010868	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1104326010869	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
1104326010870	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326010871	PYR/PP interface [polypeptide binding]; other site
1104326010872	dimer interface [polypeptide binding]; other site
1104326010873	TPP binding site [chemical binding]; other site
1104326010874	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326010875	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
1104326010876	TPP-binding site; other site
1104326010877	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
1104326010878	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
1104326010879	tetrameric interface [polypeptide binding]; other site
1104326010880	NAD binding site [chemical binding]; other site
1104326010881	catalytic residues [active]
1104326010882	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326010883	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326010884	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1104326010885	putative active site [active]
1104326010886	GMP synthase; Reviewed; Region: guaA; PRK00074
1104326010887	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1104326010888	AMP/PPi binding site [chemical binding]; other site
1104326010889	candidate oxyanion hole; other site
1104326010890	catalytic triad [active]
1104326010891	potential glutamine specificity residues [chemical binding]; other site
1104326010892	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1104326010893	ATP Binding subdomain [chemical binding]; other site
1104326010894	Ligand Binding sites [chemical binding]; other site
1104326010895	Dimerization subdomain; other site
1104326010896	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1104326010897	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1104326010898	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1104326010899	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1104326010900	active site
1104326010901	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
1104326010902	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1104326010903	generic binding surface II; other site
1104326010904	generic binding surface I; other site
1104326010905	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1104326010906	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1104326010907	active site
1104326010908	Zn binding site [ion binding]; other site
1104326010909	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1104326010910	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1104326010911	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326010912	putative substrate translocation pore; other site
1104326010913	POT family; Region: PTR2; cl17359
1104326010914	GTP-binding protein Der; Reviewed; Region: PRK00093
1104326010915	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1104326010916	G1 box; other site
1104326010917	GTP/Mg2+ binding site [chemical binding]; other site
1104326010918	Switch I region; other site
1104326010919	G2 box; other site
1104326010920	Switch II region; other site
1104326010921	G3 box; other site
1104326010922	G4 box; other site
1104326010923	G5 box; other site
1104326010924	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1104326010925	G1 box; other site
1104326010926	GTP/Mg2+ binding site [chemical binding]; other site
1104326010927	Switch I region; other site
1104326010928	G2 box; other site
1104326010929	G3 box; other site
1104326010930	Switch II region; other site
1104326010931	G4 box; other site
1104326010932	G5 box; other site
1104326010933	potential frameshift: common BLAST hit: gi|296104191|ref|YP_003614337.1| outer membrane protein assembly complex subunit YfgL
1104326010934	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1104326010935	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1104326010936	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1104326010937	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1104326010938	dimer interface [polypeptide binding]; other site
1104326010939	motif 1; other site
1104326010940	active site
1104326010941	motif 2; other site
1104326010942	motif 3; other site
1104326010943	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1104326010944	anticodon binding site; other site
1104326010945	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1104326010946	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1104326010947	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1104326010948	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1104326010949	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326010950	non-specific DNA binding site [nucleotide binding]; other site
1104326010951	salt bridge; other site
1104326010952	sequence-specific DNA binding site [nucleotide binding]; other site
1104326010953	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1104326010954	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1104326010955	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326010956	FeS/SAM binding site; other site
1104326010957	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1104326010958	active site
1104326010959	multimer interface [polypeptide binding]; other site
1104326010960	penicillin-binding protein 1C; Provisional; Region: PRK11240
1104326010961	Transglycosylase; Region: Transgly; pfam00912
1104326010962	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1104326010963	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1104326010964	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1104326010965	MG2 domain; Region: A2M_N; pfam01835
1104326010966	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1104326010967	surface patch; other site
1104326010968	thioester region; other site
1104326010969	specificity defining residues; other site
1104326010970	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1104326010971	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326010972	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326010973	active site turn [active]
1104326010974	phosphorylation site [posttranslational modification]
1104326010975	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1104326010976	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
1104326010977	NAD binding site [chemical binding]; other site
1104326010978	sugar binding site [chemical binding]; other site
1104326010979	divalent metal binding site [ion binding]; other site
1104326010980	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1104326010981	dimer interface [polypeptide binding]; other site
1104326010982	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1104326010983	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1104326010984	active site residue [active]
1104326010985	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1104326010986	active site residue [active]
1104326010987	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326010988	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326010989	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1104326010990	putative active site [active]
1104326010991	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1104326010992	aminopeptidase B; Provisional; Region: PRK05015
1104326010993	Peptidase; Region: DUF3663; pfam12404
1104326010994	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1104326010995	interface (dimer of trimers) [polypeptide binding]; other site
1104326010996	Substrate-binding/catalytic site; other site
1104326010997	Zn-binding sites [ion binding]; other site
1104326010998	hypothetical protein; Provisional; Region: PRK10721
1104326010999	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1104326011000	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1104326011001	catalytic loop [active]
1104326011002	iron binding site [ion binding]; other site
1104326011003	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1104326011004	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1104326011005	nucleotide binding site [chemical binding]; other site
1104326011006	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1104326011007	SBD interface [polypeptide binding]; other site
1104326011008	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1104326011009	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1104326011010	HSP70 interaction site [polypeptide binding]; other site
1104326011011	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1104326011012	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1104326011013	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1104326011014	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1104326011015	trimerization site [polypeptide binding]; other site
1104326011016	active site
1104326011017	cysteine desulfurase; Provisional; Region: PRK14012
1104326011018	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1104326011019	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326011020	catalytic residue [active]
1104326011021	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1104326011022	Rrf2 family protein; Region: rrf2_super; TIGR00738
1104326011023	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1104326011024	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1104326011025	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1104326011026	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1104326011027	active site
1104326011028	dimerization interface [polypeptide binding]; other site
1104326011029	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1104326011030	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1104326011031	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1104326011032	PRD domain; Region: PRD; pfam00874
1104326011033	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1104326011034	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011035	putative substrate translocation pore; other site
1104326011036	Predicted membrane protein [Function unknown]; Region: COG2259
1104326011037	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1104326011038	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1104326011039	dimer interface [polypeptide binding]; other site
1104326011040	active site
1104326011041	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1104326011042	folate binding site [chemical binding]; other site
1104326011043	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1104326011044	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1104326011045	heme-binding site [chemical binding]; other site
1104326011046	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1104326011047	FAD binding pocket [chemical binding]; other site
1104326011048	FAD binding motif [chemical binding]; other site
1104326011049	phosphate binding motif [ion binding]; other site
1104326011050	beta-alpha-beta structure motif; other site
1104326011051	NAD binding pocket [chemical binding]; other site
1104326011052	Heme binding  pocket [chemical binding]; other site
1104326011053	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1104326011054	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1104326011055	response regulator GlrR; Provisional; Region: PRK15115
1104326011056	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326011057	active site
1104326011058	phosphorylation site [posttranslational modification]
1104326011059	intermolecular recognition site; other site
1104326011060	dimerization interface [polypeptide binding]; other site
1104326011061	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326011062	Walker A motif; other site
1104326011063	ATP binding site [chemical binding]; other site
1104326011064	Walker B motif; other site
1104326011065	arginine finger; other site
1104326011066	hypothetical protein; Provisional; Region: PRK10722
1104326011067	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326011068	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326011069	dimer interface [polypeptide binding]; other site
1104326011070	phosphorylation site [posttranslational modification]
1104326011071	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326011072	ATP binding site [chemical binding]; other site
1104326011073	Mg2+ binding site [ion binding]; other site
1104326011074	G-X-G motif; other site
1104326011075	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1104326011076	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1104326011077	dimerization interface [polypeptide binding]; other site
1104326011078	ATP binding site [chemical binding]; other site
1104326011079	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1104326011080	dimerization interface [polypeptide binding]; other site
1104326011081	ATP binding site [chemical binding]; other site
1104326011082	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1104326011083	putative active site [active]
1104326011084	catalytic triad [active]
1104326011085	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1104326011086	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326011087	substrate binding pocket [chemical binding]; other site
1104326011088	membrane-bound complex binding site; other site
1104326011089	hinge residues; other site
1104326011090	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326011091	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326011092	catalytic residue [active]
1104326011093	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1104326011094	nucleoside/Zn binding site; other site
1104326011095	dimer interface [polypeptide binding]; other site
1104326011096	catalytic motif [active]
1104326011097	hypothetical protein; Provisional; Region: PRK11590
1104326011098	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1104326011099	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1104326011100	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326011101	active site turn [active]
1104326011102	phosphorylation site [posttranslational modification]
1104326011103	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326011104	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1104326011105	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1104326011106	putative active site [active]
1104326011107	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326011108	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1104326011109	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1104326011110	putative active site [active]
1104326011111	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1104326011112	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1104326011113	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1104326011114	active site
1104326011115	hydrophilic channel; other site
1104326011116	dimerization interface [polypeptide binding]; other site
1104326011117	catalytic residues [active]
1104326011118	active site lid [active]
1104326011119	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1104326011120	Recombination protein O N terminal; Region: RecO_N; pfam11967
1104326011121	Recombination protein O C terminal; Region: RecO_C; pfam02565
1104326011122	GTPase Era; Reviewed; Region: era; PRK00089
1104326011123	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1104326011124	G1 box; other site
1104326011125	GTP/Mg2+ binding site [chemical binding]; other site
1104326011126	Switch I region; other site
1104326011127	G2 box; other site
1104326011128	Switch II region; other site
1104326011129	G3 box; other site
1104326011130	G4 box; other site
1104326011131	G5 box; other site
1104326011132	KH domain; Region: KH_2; pfam07650
1104326011133	ribonuclease III; Reviewed; Region: rnc; PRK00102
1104326011134	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1104326011135	dimerization interface [polypeptide binding]; other site
1104326011136	active site
1104326011137	metal binding site [ion binding]; metal-binding site
1104326011138	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1104326011139	dsRNA binding site [nucleotide binding]; other site
1104326011140	signal peptidase I; Provisional; Region: PRK10861
1104326011141	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1104326011142	Catalytic site [active]
1104326011143	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1104326011144	GTP-binding protein LepA; Provisional; Region: PRK05433
1104326011145	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1104326011146	G1 box; other site
1104326011147	putative GEF interaction site [polypeptide binding]; other site
1104326011148	GTP/Mg2+ binding site [chemical binding]; other site
1104326011149	Switch I region; other site
1104326011150	G2 box; other site
1104326011151	G3 box; other site
1104326011152	Switch II region; other site
1104326011153	G4 box; other site
1104326011154	G5 box; other site
1104326011155	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1104326011156	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1104326011157	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1104326011158	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1104326011159	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1104326011160	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1104326011161	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1104326011162	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1104326011163	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1104326011164	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1104326011165	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326011166	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326011167	DNA binding residues [nucleotide binding]
1104326011168	L-aspartate oxidase; Provisional; Region: PRK09077
1104326011169	L-aspartate oxidase; Provisional; Region: PRK06175
1104326011170	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1104326011171	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1104326011172	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326011173	S-adenosylmethionine binding site [chemical binding]; other site
1104326011174	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1104326011175	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1104326011176	ATP binding site [chemical binding]; other site
1104326011177	Mg++ binding site [ion binding]; other site
1104326011178	motif III; other site
1104326011179	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326011180	nucleotide binding region [chemical binding]; other site
1104326011181	ATP-binding site [chemical binding]; other site
1104326011182	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1104326011183	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1104326011184	ligand binding site [chemical binding]; other site
1104326011185	active site
1104326011186	UGI interface [polypeptide binding]; other site
1104326011187	catalytic site [active]
1104326011188	putative methyltransferase; Provisional; Region: PRK10864
1104326011189	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1104326011190	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1104326011191	thioredoxin 2; Provisional; Region: PRK10996
1104326011192	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1104326011193	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1104326011194	catalytic residues [active]
1104326011195	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1104326011196	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1104326011197	CoA binding domain; Region: CoA_binding_2; pfam13380
1104326011198	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1104326011199	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1104326011200	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1104326011201	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1104326011202	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1104326011203	domain interface [polypeptide binding]; other site
1104326011204	putative active site [active]
1104326011205	catalytic site [active]
1104326011206	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1104326011207	domain interface [polypeptide binding]; other site
1104326011208	putative active site [active]
1104326011209	catalytic site [active]
1104326011210	lipoprotein; Provisional; Region: PRK10759
1104326011211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011212	putative substrate translocation pore; other site
1104326011213	protein disaggregation chaperone; Provisional; Region: PRK10865
1104326011214	Clp amino terminal domain; Region: Clp_N; pfam02861
1104326011215	Clp amino terminal domain; Region: Clp_N; pfam02861
1104326011216	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326011217	Walker A motif; other site
1104326011218	ATP binding site [chemical binding]; other site
1104326011219	Walker B motif; other site
1104326011220	arginine finger; other site
1104326011221	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326011222	Walker A motif; other site
1104326011223	ATP binding site [chemical binding]; other site
1104326011224	Walker B motif; other site
1104326011225	arginine finger; other site
1104326011226	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1104326011227	hypothetical protein; Provisional; Region: PRK10723
1104326011228	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1104326011229	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1104326011230	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326011231	RNA binding surface [nucleotide binding]; other site
1104326011232	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1104326011233	active site
1104326011234	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1104326011235	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1104326011236	30S subunit binding site; other site
1104326011237	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1104326011238	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1104326011239	Prephenate dehydratase; Region: PDT; pfam00800
1104326011240	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1104326011241	putative L-Phe binding site [chemical binding]; other site
1104326011242	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1104326011243	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1104326011244	Chorismate mutase type II; Region: CM_2; cl00693
1104326011245	prephenate dehydrogenase; Validated; Region: PRK08507
1104326011246	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1104326011247	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1104326011248	lipoprotein; Provisional; Region: PRK11443
1104326011249	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
1104326011250	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1104326011251	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1104326011252	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326011253	metal binding site [ion binding]; metal-binding site
1104326011254	active site
1104326011255	I-site; other site
1104326011256	putative outer membrane lipoprotein; Provisional; Region: PRK09967
1104326011257	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326011258	ligand binding site [chemical binding]; other site
1104326011259	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
1104326011260	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
1104326011261	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
1104326011262	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1104326011263	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1104326011264	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1104326011265	RimM N-terminal domain; Region: RimM; pfam01782
1104326011266	PRC-barrel domain; Region: PRC; pfam05239
1104326011267	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1104326011268	signal recognition particle protein; Provisional; Region: PRK10867
1104326011269	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1104326011270	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1104326011271	P loop; other site
1104326011272	GTP binding site [chemical binding]; other site
1104326011273	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1104326011274	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1104326011275	hypothetical protein; Provisional; Region: PRK11573
1104326011276	Domain of unknown function DUF21; Region: DUF21; pfam01595
1104326011277	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1104326011278	Transporter associated domain; Region: CorC_HlyC; smart01091
1104326011279	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1104326011280	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1104326011281	dimer interface [polypeptide binding]; other site
1104326011282	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1104326011283	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1104326011284	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1104326011285	recombination and repair protein; Provisional; Region: PRK10869
1104326011286	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1104326011287	Walker A/P-loop; other site
1104326011288	ATP binding site [chemical binding]; other site
1104326011289	Q-loop/lid; other site
1104326011290	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1104326011291	ABC transporter signature motif; other site
1104326011292	Walker B; other site
1104326011293	D-loop; other site
1104326011294	H-loop/switch region; other site
1104326011295	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1104326011296	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1104326011297	hypothetical protein; Validated; Region: PRK01777
1104326011298	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1104326011299	putative coenzyme Q binding site [chemical binding]; other site
1104326011300	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1104326011301	SmpB-tmRNA interface; other site
1104326011302	integrase; Provisional; Region: PRK09692
1104326011303	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1104326011304	active site
1104326011305	Int/Topo IB signature motif; other site
1104326011306	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cd02019
1104326011307	active site
1104326011308	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1104326011309	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1104326011310	Part of AAA domain; Region: AAA_19; pfam13245
1104326011311	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326011312	Walker A/P-loop; other site
1104326011313	ATP binding site [chemical binding]; other site
1104326011314	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1104326011315	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1104326011316	putative active site [active]
1104326011317	putative metal-binding site [ion binding]; other site
1104326011318	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1104326011319	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1104326011320	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1104326011321	DNA binding site [nucleotide binding]
1104326011322	active site
1104326011323	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1104326011324	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1104326011325	tetramer interface [polypeptide binding]; other site
1104326011326	active site
1104326011327	Mg2+/Mn2+ binding site [ion binding]; other site
1104326011328	YceI-like domain; Region: YceI; pfam04264
1104326011329	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
1104326011330	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1104326011331	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326011332	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326011333	DNA binding residues [nucleotide binding]
1104326011334	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326011335	TPR motif; other site
1104326011336	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1104326011337	binding surface
1104326011338	potential frameshift: common BLAST hit: gi|296104317|ref|YP_003614463.1| putative outer membrane adhesin like protein
1104326011339	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1104326011340	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1104326011341	putative active site [active]
1104326011342	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1104326011343	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326011344	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326011345	Walker A/P-loop; other site
1104326011346	ATP binding site [chemical binding]; other site
1104326011347	Q-loop/lid; other site
1104326011348	ABC transporter signature motif; other site
1104326011349	Walker B; other site
1104326011350	D-loop; other site
1104326011351	H-loop/switch region; other site
1104326011352	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1104326011353	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326011354	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326011355	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1104326011356	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1104326011357	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326011358	sequence-specific DNA binding site [nucleotide binding]; other site
1104326011359	salt bridge; other site
1104326011360	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1104326011361	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1104326011362	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326011363	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326011364	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326011365	SnoaL-like domain; Region: SnoaL_2; pfam12680
1104326011366	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1104326011367	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1104326011368	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326011369	homodimer interface [polypeptide binding]; other site
1104326011370	catalytic residue [active]
1104326011371	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326011372	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326011373	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326011374	dimerization interface [polypeptide binding]; other site
1104326011375	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
1104326011376	putative NAD(P) binding site [chemical binding]; other site
1104326011377	homodimer interface [polypeptide binding]; other site
1104326011378	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1104326011379	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326011380	S-adenosylmethionine binding site [chemical binding]; other site
1104326011381	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1104326011382	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1104326011383	PYR/PP interface [polypeptide binding]; other site
1104326011384	dimer interface [polypeptide binding]; other site
1104326011385	TPP binding site [chemical binding]; other site
1104326011386	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1104326011387	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1104326011388	TPP-binding site [chemical binding]; other site
1104326011389	dimer interface [polypeptide binding]; other site
1104326011390	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1104326011391	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326011392	NAD(P) binding site [chemical binding]; other site
1104326011393	active site
1104326011394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011395	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326011396	putative substrate translocation pore; other site
1104326011397	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011398	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1104326011399	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326011400	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1104326011401	dimerization interface [polypeptide binding]; other site
1104326011402	substrate binding pocket [chemical binding]; other site
1104326011403	putative deaminase; Validated; Region: PRK06846
1104326011404	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1104326011405	active site
1104326011406	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1104326011407	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1104326011408	putative substrate binding site [chemical binding]; other site
1104326011409	nucleotide binding site [chemical binding]; other site
1104326011410	nucleotide binding site [chemical binding]; other site
1104326011411	homodimer interface [polypeptide binding]; other site
1104326011412	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1104326011413	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
1104326011414	CoA binding domain; Region: CoA_binding; pfam02629
1104326011415	CoA-ligase; Region: Ligase_CoA; pfam00549
1104326011416	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1104326011417	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1104326011418	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1104326011419	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1104326011420	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326011421	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326011422	dimerization interface [polypeptide binding]; other site
1104326011423	Proteolipid membrane potential modulator; Region: Pmp3; cl00431
1104326011424	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1104326011425	active site residue [active]
1104326011426	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1104326011427	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1104326011428	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1104326011429	hypothetical protein; Provisional; Region: PRK10556
1104326011430	hypothetical protein; Provisional; Region: PRK10132
1104326011431	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1104326011432	catalytic residues [active]
1104326011433	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1104326011434	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1104326011435	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1104326011436	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1104326011437	active site
1104326011438	dimer interface [polypeptide binding]; other site
1104326011439	catalytic residues [active]
1104326011440	effector binding site; other site
1104326011441	R2 peptide binding site; other site
1104326011442	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1104326011443	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1104326011444	dimer interface [polypeptide binding]; other site
1104326011445	putative radical transfer pathway; other site
1104326011446	diiron center [ion binding]; other site
1104326011447	tyrosyl radical; other site
1104326011448	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1104326011449	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1104326011450	Walker A/P-loop; other site
1104326011451	ATP binding site [chemical binding]; other site
1104326011452	Q-loop/lid; other site
1104326011453	ABC transporter signature motif; other site
1104326011454	Walker B; other site
1104326011455	D-loop; other site
1104326011456	H-loop/switch region; other site
1104326011457	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1104326011458	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1104326011459	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326011460	dimer interface [polypeptide binding]; other site
1104326011461	conserved gate region; other site
1104326011462	putative PBP binding loops; other site
1104326011463	ABC-ATPase subunit interface; other site
1104326011464	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1104326011465	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1104326011466	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1104326011467	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011468	transcriptional repressor MprA; Provisional; Region: PRK10870
1104326011469	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326011470	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1104326011471	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326011472	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326011473	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1104326011474	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011475	putative substrate translocation pore; other site
1104326011476	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011477	2-isopropylmalate synthase; Validated; Region: PRK03739
1104326011478	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
1104326011479	active site
1104326011480	catalytic residues [active]
1104326011481	metal binding site [ion binding]; metal-binding site
1104326011482	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1104326011483	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326011484	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1104326011485	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326011486	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1104326011487	glutamate--cysteine ligase; Provisional; Region: PRK02107
1104326011488	Predicted membrane protein [Function unknown]; Region: COG1238
1104326011489	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1104326011490	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326011491	motif II; other site
1104326011492	carbon storage regulator; Provisional; Region: PRK01712
1104326011493	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1104326011494	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1104326011495	motif 1; other site
1104326011496	active site
1104326011497	motif 2; other site
1104326011498	motif 3; other site
1104326011499	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1104326011500	DHHA1 domain; Region: DHHA1; pfam02272
1104326011501	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1104326011502	recombinase A; Provisional; Region: recA; PRK09354
1104326011503	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1104326011504	hexamer interface [polypeptide binding]; other site
1104326011505	Walker A motif; other site
1104326011506	ATP binding site [chemical binding]; other site
1104326011507	Walker B motif; other site
1104326011508	hypothetical protein; Validated; Region: PRK03661
1104326011509	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1104326011510	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1104326011511	metal binding site [ion binding]; metal-binding site
1104326011512	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1104326011513	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326011514	ABC-ATPase subunit  interface; other site
1104326011515	dimer interface [polypeptide binding]; other site
1104326011516	putative PBP binding regions; other site
1104326011517	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1104326011518	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1104326011519	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1104326011520	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326011521	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326011522	catalytic residue [active]
1104326011523	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; cl01515
1104326011524	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1104326011525	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1104326011526	Nucleoside recognition; Region: Gate; pfam07670
1104326011527	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1104326011528	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1104326011529	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1104326011530	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1104326011531	putative NAD(P) binding site [chemical binding]; other site
1104326011532	active site
1104326011533	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1104326011534	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1104326011535	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1104326011536	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326011537	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1104326011538	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1104326011539	putative active site [active]
1104326011540	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1104326011541	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1104326011542	GAF domain; Region: GAF; pfam01590
1104326011543	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326011544	Walker A motif; other site
1104326011545	ATP binding site [chemical binding]; other site
1104326011546	Walker B motif; other site
1104326011547	arginine finger; other site
1104326011548	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1104326011549	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1104326011550	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1104326011551	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1104326011552	iron binding site [ion binding]; other site
1104326011553	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1104326011554	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326011555	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326011556	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1104326011557	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326011558	active site turn [active]
1104326011559	phosphorylation site [posttranslational modification]
1104326011560	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1104326011561	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1104326011562	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1104326011563	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1104326011564	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1104326011565	Acylphosphatase; Region: Acylphosphatase; pfam00708
1104326011566	HypF finger; Region: zf-HYPF; pfam07503
1104326011567	HypF finger; Region: zf-HYPF; pfam07503
1104326011568	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1104326011569	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1104326011570	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1104326011571	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326011572	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326011573	DNA binding site [nucleotide binding]
1104326011574	domain linker motif; other site
1104326011575	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1104326011576	dimerization interface (closed form) [polypeptide binding]; other site
1104326011577	ligand binding site [chemical binding]; other site
1104326011578	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1104326011579	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326011580	active site turn [active]
1104326011581	phosphorylation site [posttranslational modification]
1104326011582	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1104326011583	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1104326011584	beta-galactosidase; Region: BGL; TIGR03356
1104326011585	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1104326011586	nickel binding site [ion binding]; other site
1104326011587	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1104326011588	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1104326011589	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1104326011590	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1104326011591	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1104326011592	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1104326011593	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1104326011594	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1104326011595	NADH dehydrogenase; Region: NADHdh; cl00469
1104326011596	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1104326011597	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1104326011598	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1104326011599	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1104326011600	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1104326011601	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1104326011602	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1104326011603	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1104326011604	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1104326011605	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1104326011606	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1104326011607	dimerization interface [polypeptide binding]; other site
1104326011608	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1104326011609	ATP binding site [chemical binding]; other site
1104326011610	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1104326011611	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1104326011612	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1104326011613	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326011614	Walker A motif; other site
1104326011615	ATP binding site [chemical binding]; other site
1104326011616	Walker B motif; other site
1104326011617	arginine finger; other site
1104326011618	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1104326011619	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1104326011620	proposed F420-0 ABC transporter, periplasmic F420-0 binding protein; Region: F420-O_ABCperi; TIGR03868
1104326011621	intersubunit interface [polypeptide binding]; other site
1104326011622	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1104326011623	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326011624	dimer interface [polypeptide binding]; other site
1104326011625	putative PBP binding regions; other site
1104326011626	ABC-ATPase subunit  interface; other site
1104326011627	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1104326011628	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1104326011629	Walker A/P-loop; other site
1104326011630	ATP binding site [chemical binding]; other site
1104326011631	Q-loop/lid; other site
1104326011632	ABC transporter signature motif; other site
1104326011633	Walker B; other site
1104326011634	D-loop; other site
1104326011635	H-loop/switch region; other site
1104326011636	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011637	putative substrate translocation pore; other site
1104326011638	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1104326011639	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
1104326011640	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1104326011641	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1104326011642	MutS domain I; Region: MutS_I; pfam01624
1104326011643	MutS domain II; Region: MutS_II; pfam05188
1104326011644	MutS domain III; Region: MutS_III; pfam05192
1104326011645	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1104326011646	Walker A/P-loop; other site
1104326011647	ATP binding site [chemical binding]; other site
1104326011648	Q-loop/lid; other site
1104326011649	ABC transporter signature motif; other site
1104326011650	Walker B; other site
1104326011651	D-loop; other site
1104326011652	H-loop/switch region; other site
1104326011653	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1104326011654	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1104326011655	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1104326011656	Flavoprotein; Region: Flavoprotein; pfam02441
1104326011657	MarR family; Region: MarR_2; cl17246
1104326011658	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326011659	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326011660	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326011661	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326011662	putative effector binding pocket; other site
1104326011663	dimerization interface [polypeptide binding]; other site
1104326011664	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011665	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1104326011666	putative substrate translocation pore; other site
1104326011667	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1104326011668	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1104326011669	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1104326011670	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326011671	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1104326011672	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326011673	DNA binding residues [nucleotide binding]
1104326011674	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1104326011675	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326011676	Peptidase family M23; Region: Peptidase_M23; pfam01551
1104326011677	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1104326011678	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326011679	S-adenosylmethionine binding site [chemical binding]; other site
1104326011680	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1104326011681	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1104326011682	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1104326011683	Permutation of conserved domain; other site
1104326011684	active site
1104326011685	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1104326011686	homotrimer interaction site [polypeptide binding]; other site
1104326011687	zinc binding site [ion binding]; other site
1104326011688	CDP-binding sites; other site
1104326011689	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1104326011690	substrate binding site; other site
1104326011691	dimer interface; other site
1104326011692	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1104326011693	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1104326011694	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1104326011695	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1104326011696	ligand-binding site [chemical binding]; other site
1104326011697	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1104326011698	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1104326011699	CysD dimerization site [polypeptide binding]; other site
1104326011700	G1 box; other site
1104326011701	putative GEF interaction site [polypeptide binding]; other site
1104326011702	GTP/Mg2+ binding site [chemical binding]; other site
1104326011703	Switch I region; other site
1104326011704	G2 box; other site
1104326011705	G3 box; other site
1104326011706	Switch II region; other site
1104326011707	G4 box; other site
1104326011708	G5 box; other site
1104326011709	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1104326011710	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1104326011711	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1104326011712	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1104326011713	Active Sites [active]
1104326011714	siroheme synthase; Provisional; Region: cysG; PRK10637
1104326011715	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1104326011716	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1104326011717	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1104326011718	active site
1104326011719	SAM binding site [chemical binding]; other site
1104326011720	homodimer interface [polypeptide binding]; other site
1104326011721	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1104326011722	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1104326011723	metal binding site [ion binding]; metal-binding site
1104326011724	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1104326011725	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1104326011726	Active Sites [active]
1104326011727	sulfite reductase subunit beta; Provisional; Region: PRK13504
1104326011728	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1104326011729	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1104326011730	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1104326011731	Flavodoxin; Region: Flavodoxin_1; pfam00258
1104326011732	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1104326011733	FAD binding pocket [chemical binding]; other site
1104326011734	FAD binding motif [chemical binding]; other site
1104326011735	catalytic residues [active]
1104326011736	NAD binding pocket [chemical binding]; other site
1104326011737	phosphate binding motif [ion binding]; other site
1104326011738	beta-alpha-beta structure motif; other site
1104326011739	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1104326011740	active site
1104326011741	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1104326011742	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1104326011743	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1104326011744	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1104326011745	putative active site cavity [active]
1104326011746	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1104326011747	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1104326011748	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1104326011749	active site turn [active]
1104326011750	phosphorylation site [posttranslational modification]
1104326011751	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326011752	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326011753	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1104326011754	putative active site [active]
1104326011755	fatty acyl CoA reductases (FARs), extended (e) SDRs; Region: FAR-N_SDR_e; cd05236
1104326011756	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1104326011757	putative NAD(P) binding site [chemical binding]; other site
1104326011758	active site
1104326011759	putative substrate binding site [chemical binding]; other site
1104326011760	enolase; Provisional; Region: eno; PRK00077
1104326011761	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1104326011762	dimer interface [polypeptide binding]; other site
1104326011763	metal binding site [ion binding]; metal-binding site
1104326011764	substrate binding pocket [chemical binding]; other site
1104326011765	CTP synthetase; Validated; Region: pyrG; PRK05380
1104326011766	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1104326011767	Catalytic site [active]
1104326011768	active site
1104326011769	UTP binding site [chemical binding]; other site
1104326011770	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1104326011771	active site
1104326011772	putative oxyanion hole; other site
1104326011773	catalytic triad [active]
1104326011774	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1104326011775	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1104326011776	homodimer interface [polypeptide binding]; other site
1104326011777	metal binding site [ion binding]; metal-binding site
1104326011778	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1104326011779	homodimer interface [polypeptide binding]; other site
1104326011780	active site
1104326011781	putative chemical substrate binding site [chemical binding]; other site
1104326011782	metal binding site [ion binding]; metal-binding site
1104326011783	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1104326011784	HD domain; Region: HD_4; pfam13328
1104326011785	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1104326011786	synthetase active site [active]
1104326011787	NTP binding site [chemical binding]; other site
1104326011788	metal binding site [ion binding]; metal-binding site
1104326011789	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1104326011790	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1104326011791	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1104326011792	TRAM domain; Region: TRAM; pfam01938
1104326011793	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1104326011794	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326011795	S-adenosylmethionine binding site [chemical binding]; other site
1104326011796	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1104326011797	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1104326011798	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326011799	dimerization interface [polypeptide binding]; other site
1104326011800	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326011801	dimer interface [polypeptide binding]; other site
1104326011802	phosphorylation site [posttranslational modification]
1104326011803	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326011804	ATP binding site [chemical binding]; other site
1104326011805	Mg2+ binding site [ion binding]; other site
1104326011806	G-X-G motif; other site
1104326011807	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1104326011808	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326011809	active site
1104326011810	phosphorylation site [posttranslational modification]
1104326011811	intermolecular recognition site; other site
1104326011812	dimerization interface [polypeptide binding]; other site
1104326011813	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1104326011814	putative binding surface; other site
1104326011815	active site
1104326011816	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1104326011817	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1104326011818	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1104326011819	active site
1104326011820	tetramer interface [polypeptide binding]; other site
1104326011821	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1104326011822	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1104326011823	active site
1104326011824	tetramer interface [polypeptide binding]; other site
1104326011825	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011826	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326011827	putative substrate translocation pore; other site
1104326011828	flavodoxin; Provisional; Region: PRK08105
1104326011829	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1104326011830	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1104326011831	probable active site [active]
1104326011832	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1104326011833	SecY interacting protein Syd; Provisional; Region: PRK04968
1104326011834	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1104326011835	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1104326011836	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1104326011837	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1104326011838	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1104326011839	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1104326011840	serine transporter; Region: stp; TIGR00814
1104326011841	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1104326011842	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1104326011843	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1104326011844	flap endonuclease-like protein; Provisional; Region: PRK09482
1104326011845	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1104326011846	active site
1104326011847	metal binding site 1 [ion binding]; metal-binding site
1104326011848	putative 5' ssDNA interaction site; other site
1104326011849	metal binding site 3; metal-binding site
1104326011850	metal binding site 2 [ion binding]; metal-binding site
1104326011851	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1104326011852	putative DNA binding site [nucleotide binding]; other site
1104326011853	putative metal binding site [ion binding]; other site
1104326011854	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1104326011855	FtsJ-like methyltransferase; Region: FtsJ; cl17430
1104326011856	hypothetical protein; Provisional; Region: PRK10873
1104326011857	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1104326011858	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326011859	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1104326011860	dimerization interface [polypeptide binding]; other site
1104326011861	substrate binding pocket [chemical binding]; other site
1104326011862	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1104326011863	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1104326011864	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1104326011865	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1104326011866	catalytic residue [active]
1104326011867	Fe-S metabolism associated domain; Region: SufE; cl00951
1104326011868	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1104326011869	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1104326011870	putative ATP binding site [chemical binding]; other site
1104326011871	putative substrate interface [chemical binding]; other site
1104326011872	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1104326011873	MltA specific insert domain; Region: MltA; pfam03562
1104326011874	3D domain; Region: 3D; pfam06725
1104326011875	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1104326011876	AMIN domain; Region: AMIN; pfam11741
1104326011877	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1104326011878	active site
1104326011879	metal binding site [ion binding]; metal-binding site
1104326011880	N-acetylglutamate synthase; Validated; Region: PRK05279
1104326011881	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1104326011882	putative feedback inhibition sensing region; other site
1104326011883	putative nucleotide binding site [chemical binding]; other site
1104326011884	putative substrate binding site [chemical binding]; other site
1104326011885	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326011886	Coenzyme A binding pocket [chemical binding]; other site
1104326011887	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1104326011888	AAA domain; Region: AAA_30; pfam13604
1104326011889	Family description; Region: UvrD_C_2; pfam13538
1104326011890	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1104326011891	protease3; Provisional; Region: PRK15101
1104326011892	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1104326011893	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1104326011894	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1104326011895	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1104326011896	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1104326011897	hypothetical protein; Provisional; Region: PRK10332
1104326011898	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1104326011899	hypothetical protein; Provisional; Region: PRK11521
1104326011900	hypothetical protein; Provisional; Region: PRK10557
1104326011901	hypothetical protein; Provisional; Region: PRK10506
1104326011902	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1104326011903	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1104326011904	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1104326011905	dimerization interface [polypeptide binding]; other site
1104326011906	active site
1104326011907	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1104326011908	potential frameshift: common BLAST hit: gi|296104488|ref|YP_003614634.1| putative phosphoenolpyruvate-protein phosphotransferase
1104326011909	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1104326011910	putative active site [active]
1104326011911	Ap4A binding site [chemical binding]; other site
1104326011912	nudix motif; other site
1104326011913	putative metal binding site [ion binding]; other site
1104326011914	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1104326011915	putative DNA-binding cleft [nucleotide binding]; other site
1104326011916	putative DNA clevage site; other site
1104326011917	molecular lever; other site
1104326011918	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1104326011919	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326011920	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326011921	active site
1104326011922	catalytic tetrad [active]
1104326011923	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1104326011924	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326011925	putative substrate translocation pore; other site
1104326011926	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1104326011927	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1104326011928	putative acyl-acceptor binding pocket; other site
1104326011929	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1104326011930	acyl-activating enzyme (AAE) consensus motif; other site
1104326011931	putative AMP binding site [chemical binding]; other site
1104326011932	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1104326011933	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326011934	DNA binding site [nucleotide binding]
1104326011935	domain linker motif; other site
1104326011936	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1104326011937	dimerization interface (closed form) [polypeptide binding]; other site
1104326011938	ligand binding site [chemical binding]; other site
1104326011939	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326011940	Coenzyme A binding pocket [chemical binding]; other site
1104326011941	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1104326011942	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326011943	DNA-binding site [nucleotide binding]; DNA binding site
1104326011944	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1104326011945	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1104326011946	beta-galactosidase; Region: BGL; TIGR03356
1104326011947	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1104326011948	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1104326011949	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326011950	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326011951	DNA binding site [nucleotide binding]
1104326011952	domain linker motif; other site
1104326011953	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1104326011954	dimerization interface (closed form) [polypeptide binding]; other site
1104326011955	ligand binding site [chemical binding]; other site
1104326011956	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1104326011957	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1104326011958	active site
1104326011959	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1104326011960	substrate binding site [chemical binding]; other site
1104326011961	catalytic residues [active]
1104326011962	dimer interface [polypeptide binding]; other site
1104326011963	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1104326011964	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326011965	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326011966	dimerization interface [polypeptide binding]; other site
1104326011967	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1104326011968	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1104326011969	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; cl04524
1104326011970	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1104326011971	CblD like pilus biogenesis initiator; Region: CblD; cl06460
1104326011972	putative racemase; Provisional; Region: PRK10200
1104326011973	aspartate racemase; Region: asp_race; TIGR00035
1104326011974	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1104326011975	LPS O-antigen length regulator; Provisional; Region: PRK10381
1104326011976	Chain length determinant protein; Region: Wzz; cl15801
1104326011977	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1104326011978	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326011979	dimer interface [polypeptide binding]; other site
1104326011980	conserved gate region; other site
1104326011981	putative PBP binding loops; other site
1104326011982	ABC-ATPase subunit interface; other site
1104326011983	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1104326011984	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326011985	dimer interface [polypeptide binding]; other site
1104326011986	conserved gate region; other site
1104326011987	putative PBP binding loops; other site
1104326011988	ABC-ATPase subunit interface; other site
1104326011989	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1104326011990	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1104326011991	Walker A/P-loop; other site
1104326011992	ATP binding site [chemical binding]; other site
1104326011993	Q-loop/lid; other site
1104326011994	ABC transporter signature motif; other site
1104326011995	Walker B; other site
1104326011996	D-loop; other site
1104326011997	H-loop/switch region; other site
1104326011998	TOBE domain; Region: TOBE; pfam03459
1104326011999	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1104326012000	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1104326012001	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1104326012002	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012003	putative substrate translocation pore; other site
1104326012004	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012005	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1104326012006	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1104326012007	NADP binding site [chemical binding]; other site
1104326012008	homodimer interface [polypeptide binding]; other site
1104326012009	active site
1104326012010	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1104326012011	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1104326012012	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
1104326012013	putative acyltransferase; Provisional; Region: PRK05790
1104326012014	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1104326012015	dimer interface [polypeptide binding]; other site
1104326012016	active site
1104326012017	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326012018	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326012019	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1104326012020	dimerization interface [polypeptide binding]; other site
1104326012021	Predicted membrane protein [Function unknown]; Region: COG4125
1104326012022	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1104326012023	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1104326012024	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1104326012025	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1104326012026	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1104326012027	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326012028	putative DNA binding site [nucleotide binding]; other site
1104326012029	putative Zn2+ binding site [ion binding]; other site
1104326012030	AsnC family; Region: AsnC_trans_reg; pfam01037
1104326012031	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1104326012032	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326012033	Coenzyme A binding pocket [chemical binding]; other site
1104326012034	Protein of unknown function (DUF1271); Region: DUF1271; cl01443
1104326012035	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1104326012036	PAS domain; Region: PAS; smart00091
1104326012037	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326012038	ATP binding site [chemical binding]; other site
1104326012039	Mg2+ binding site [ion binding]; other site
1104326012040	G-X-G motif; other site
1104326012041	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1104326012042	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012043	active site
1104326012044	phosphorylation site [posttranslational modification]
1104326012045	intermolecular recognition site; other site
1104326012046	dimerization interface [polypeptide binding]; other site
1104326012047	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1104326012048	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1104326012049	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1104326012050	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1104326012051	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326012052	dimer interface [polypeptide binding]; other site
1104326012053	conserved gate region; other site
1104326012054	ABC-ATPase subunit interface; other site
1104326012055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326012056	dimer interface [polypeptide binding]; other site
1104326012057	conserved gate region; other site
1104326012058	putative PBP binding loops; other site
1104326012059	ABC-ATPase subunit interface; other site
1104326012060	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1104326012061	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1104326012062	Walker A/P-loop; other site
1104326012063	ATP binding site [chemical binding]; other site
1104326012064	Q-loop/lid; other site
1104326012065	ABC transporter signature motif; other site
1104326012066	Walker B; other site
1104326012067	D-loop; other site
1104326012068	H-loop/switch region; other site
1104326012069	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1104326012070	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1104326012071	PA-IL-like protein; Region: PA-IL; pfam07828
1104326012072	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1104326012073	Transposase; Region: HTH_Tnp_1; pfam01527
1104326012074	Integrase core domain; Region: rve_3; pfam13683
1104326012075	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1104326012076	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326012077	Walker B; other site
1104326012078	D-loop; other site
1104326012079	H-loop/switch region; other site
1104326012080	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1104326012081	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326012082	Peptidase family M23; Region: Peptidase_M23; pfam01551
1104326012083	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1104326012084	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1104326012085	active site
1104326012086	metal binding site [ion binding]; metal-binding site
1104326012087	nudix motif; other site
1104326012088	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1104326012089	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1104326012090	dimer interface [polypeptide binding]; other site
1104326012091	putative anticodon binding site; other site
1104326012092	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1104326012093	motif 1; other site
1104326012094	active site
1104326012095	motif 2; other site
1104326012096	motif 3; other site
1104326012097	peptide chain release factor 2; Provisional; Region: PRK08787
1104326012098	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1104326012099	RF-1 domain; Region: RF-1; pfam00472
1104326012100	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1104326012101	DHH family; Region: DHH; pfam01368
1104326012102	DHHA1 domain; Region: DHHA1; pfam02272
1104326012103	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1104326012104	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1104326012105	dimerization domain [polypeptide binding]; other site
1104326012106	dimer interface [polypeptide binding]; other site
1104326012107	catalytic residues [active]
1104326012108	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1104326012109	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1104326012110	active site
1104326012111	Int/Topo IB signature motif; other site
1104326012112	flavodoxin FldB; Provisional; Region: PRK12359
1104326012113	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1104326012114	hypothetical protein; Provisional; Region: PRK10878
1104326012115	putative global regulator; Reviewed; Region: PRK09559
1104326012116	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1104326012117	hemolysin; Provisional; Region: PRK15087
1104326012118	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1104326012119	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326012120	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326012121	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1104326012122	putative active site [active]
1104326012123	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1104326012124	beta-galactosidase; Region: BGL; TIGR03356
1104326012125	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
1104326012126	classical (c) SDRs; Region: SDR_c; cd05233
1104326012127	NAD(P) binding site [chemical binding]; other site
1104326012128	active site
1104326012129	glycine dehydrogenase; Provisional; Region: PRK05367
1104326012130	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1104326012131	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326012132	tetramer interface [polypeptide binding]; other site
1104326012133	catalytic residue [active]
1104326012134	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1104326012135	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1104326012136	tetramer interface [polypeptide binding]; other site
1104326012137	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326012138	catalytic residue [active]
1104326012139	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1104326012140	lipoyl attachment site [posttranslational modification]; other site
1104326012141	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1104326012142	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1104326012143	oxidoreductase; Provisional; Region: PRK08013
1104326012144	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1104326012145	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1104326012146	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1104326012147	potential frameshift: common BLAST hit: gi|296104571|ref|YP_003614717.1| Xaa-Pro aminopeptidase
1104326012148	hypothetical protein; Reviewed; Region: PRK01736
1104326012149	Z-ring-associated protein; Provisional; Region: PRK10972
1104326012150	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1104326012151	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1104326012152	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1104326012153	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1104326012154	ligand binding site [chemical binding]; other site
1104326012155	NAD binding site [chemical binding]; other site
1104326012156	tetramer interface [polypeptide binding]; other site
1104326012157	catalytic site [active]
1104326012158	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1104326012159	L-serine binding site [chemical binding]; other site
1104326012160	ACT domain interface; other site
1104326012161	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1104326012162	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1104326012163	active site
1104326012164	dimer interface [polypeptide binding]; other site
1104326012165	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1104326012166	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326012167	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1104326012168	putative dimerization interface [polypeptide binding]; other site
1104326012169	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1104326012170	oxidative stress defense protein; Provisional; Region: PRK11087
1104326012171	arginine exporter protein; Provisional; Region: PRK09304
1104326012172	mechanosensitive channel MscS; Provisional; Region: PRK10334
1104326012173	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1104326012174	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1104326012175	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1104326012176	active site
1104326012177	intersubunit interface [polypeptide binding]; other site
1104326012178	zinc binding site [ion binding]; other site
1104326012179	Na+ binding site [ion binding]; other site
1104326012180	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1104326012181	Phosphoglycerate kinase; Region: PGK; pfam00162
1104326012182	substrate binding site [chemical binding]; other site
1104326012183	hinge regions; other site
1104326012184	ADP binding site [chemical binding]; other site
1104326012185	catalytic site [active]
1104326012186	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1104326012187	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1104326012188	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1104326012189	transketolase; Reviewed; Region: PRK12753
1104326012190	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1104326012191	TPP-binding site [chemical binding]; other site
1104326012192	dimer interface [polypeptide binding]; other site
1104326012193	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1104326012194	PYR/PP interface [polypeptide binding]; other site
1104326012195	dimer interface [polypeptide binding]; other site
1104326012196	TPP binding site [chemical binding]; other site
1104326012197	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1104326012198	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1104326012199	outer membrane porin, OprD family; Region: OprD; pfam03573
1104326012200	hypothetical protein; Provisional; Region: PRK07064
1104326012201	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326012202	PYR/PP interface [polypeptide binding]; other site
1104326012203	dimer interface [polypeptide binding]; other site
1104326012204	TPP binding site [chemical binding]; other site
1104326012205	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326012206	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
1104326012207	TPP-binding site [chemical binding]; other site
1104326012208	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1104326012209	Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114
1104326012210	NAD(P) binding site [chemical binding]; other site
1104326012211	catalytic residues [active]
1104326012212	L-aspartate dehydrogenase; Provisional; Region: PRK13303
1104326012213	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1104326012214	Domain of unknown function DUF108; Region: DUF108; pfam01958
1104326012215	short chain dehydrogenase; Provisional; Region: PRK07062
1104326012216	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326012217	NAD(P) binding site [chemical binding]; other site
1104326012218	active site
1104326012219	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1104326012220	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1104326012221	Cupin domain; Region: Cupin_2; pfam07883
1104326012222	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012223	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326012224	putative substrate translocation pore; other site
1104326012225	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
1104326012226	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1104326012227	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326012228	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1104326012229	active site
1104326012230	metal binding site [ion binding]; metal-binding site
1104326012231	C-terminal domain of Burkholderia sp. NF100 MhqB and similar proteins; MhqB is a type I extradiol dioxygenase involved in the catabolism of methylhydroquinone, an intermediate in the degradation of fenitrothion; Region: MhqB_like_C; cd08360
1104326012232	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1104326012233	putative active site [active]
1104326012234	putative metal binding site [ion binding]; other site
1104326012235	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1104326012236	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1104326012237	Bacterial transcriptional regulator; Region: IclR; pfam01614
1104326012238	short chain dehydrogenase; Provisional; Region: PRK12939
1104326012239	classical (c) SDRs; Region: SDR_c; cd05233
1104326012240	NAD(P) binding site [chemical binding]; other site
1104326012241	active site
1104326012242	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
1104326012243	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
1104326012244	[2Fe-2S] cluster binding site [ion binding]; other site
1104326012245	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1104326012246	hydrophobic ligand binding site; other site
1104326012247	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
1104326012248	[2Fe-2S] cluster binding site [ion binding]; other site
1104326012249	potential frameshift: common BLAST hit: gi|296104602|ref|YP_003614748.1| major facilitator transporter
1104326012250	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1104326012251	agmatinase; Region: agmatinase; TIGR01230
1104326012252	oligomer interface [polypeptide binding]; other site
1104326012253	putative active site [active]
1104326012254	Mn binding site [ion binding]; other site
1104326012255	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1104326012256	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1104326012257	dimer interface [polypeptide binding]; other site
1104326012258	active site
1104326012259	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1104326012260	catalytic residues [active]
1104326012261	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1104326012262	Virulence promoting factor; Region: YqgB; pfam11036
1104326012263	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1104326012264	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1104326012265	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1104326012266	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1104326012267	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1104326012268	active site
1104326012269	Int/Topo IB signature motif; other site
1104326012270	catalytic residues [active]
1104326012271	DNA binding site [nucleotide binding]
1104326012272	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1104326012273	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1104326012274	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012275	putative substrate translocation pore; other site
1104326012276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012277	hypothetical protein; Provisional; Region: PRK04860
1104326012278	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1104326012279	DNA-specific endonuclease I; Provisional; Region: PRK15137
1104326012280	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1104326012281	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1104326012282	RNA methyltransferase, RsmE family; Region: TIGR00046
1104326012283	glutathione synthetase; Provisional; Region: PRK05246
1104326012284	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1104326012285	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1104326012286	hypothetical protein; Validated; Region: PRK00228
1104326012287	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1104326012288	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1104326012289	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1104326012290	Walker A motif; other site
1104326012291	ATP binding site [chemical binding]; other site
1104326012292	Walker B motif; other site
1104326012293	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1104326012294	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1104326012295	catalytic residue [active]
1104326012296	YGGT family; Region: YGGT; pfam02325
1104326012297	Predicted integral membrane protein [Function unknown]; Region: COG0762
1104326012298	hypothetical protein; Validated; Region: PRK05090
1104326012299	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1104326012300	active site
1104326012301	dimerization interface [polypeptide binding]; other site
1104326012302	HemN family oxidoreductase; Provisional; Region: PRK05660
1104326012303	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326012304	FeS/SAM binding site; other site
1104326012305	HemN C-terminal domain; Region: HemN_C; pfam06969
1104326012306	hypothetical protein; Provisional; Region: PRK10626
1104326012307	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1104326012308	hypothetical protein; Provisional; Region: PRK11702
1104326012309	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1104326012310	adenine DNA glycosylase; Provisional; Region: PRK10880
1104326012311	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1104326012312	minor groove reading motif; other site
1104326012313	helix-hairpin-helix signature motif; other site
1104326012314	substrate binding pocket [chemical binding]; other site
1104326012315	active site
1104326012316	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1104326012317	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1104326012318	DNA binding and oxoG recognition site [nucleotide binding]
1104326012319	oxidative damage protection protein; Provisional; Region: PRK05408
1104326012320	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1104326012321	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1104326012322	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1104326012323	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1104326012324	catalytic residue [active]
1104326012325	nucleoside transporter; Region: 2A0110; TIGR00889
1104326012326	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1104326012327	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
1104326012328	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1104326012329	Coenzyme A transferase; Region: CoA_trans; cl17247
1104326012330	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1104326012331	citrate lyase subunit gamma; Provisional; Region: PRK13253
1104326012332	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1104326012333	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1104326012334	putative active site [active]
1104326012335	(T/H)XGH motif; other site
1104326012336	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1104326012337	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1104326012338	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1104326012339	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1104326012340	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326012341	putative active site [active]
1104326012342	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326012343	ATP binding site [chemical binding]; other site
1104326012344	Mg2+ binding site [ion binding]; other site
1104326012345	G-X-G motif; other site
1104326012346	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1104326012347	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012348	active site
1104326012349	phosphorylation site [posttranslational modification]
1104326012350	intermolecular recognition site; other site
1104326012351	dimerization interface [polypeptide binding]; other site
1104326012352	Transcriptional regulator; Region: CitT; pfam12431
1104326012353	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1104326012354	ornithine decarboxylase; Provisional; Region: PRK13578
1104326012355	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1104326012356	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1104326012357	homodimer interface [polypeptide binding]; other site
1104326012358	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326012359	catalytic residue [active]
1104326012360	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1104326012361	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1104326012362	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1104326012363	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326012364	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326012365	dimer interface [polypeptide binding]; other site
1104326012366	phosphorylation site [posttranslational modification]
1104326012367	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326012368	ATP binding site [chemical binding]; other site
1104326012369	Mg2+ binding site [ion binding]; other site
1104326012370	G-X-G motif; other site
1104326012371	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012372	Response regulator receiver domain; Region: Response_reg; pfam00072
1104326012373	active site
1104326012374	phosphorylation site [posttranslational modification]
1104326012375	intermolecular recognition site; other site
1104326012376	dimerization interface [polypeptide binding]; other site
1104326012377	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326012378	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012379	active site
1104326012380	phosphorylation site [posttranslational modification]
1104326012381	intermolecular recognition site; other site
1104326012382	dimerization interface [polypeptide binding]; other site
1104326012383	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326012384	DNA binding residues [nucleotide binding]
1104326012385	dimerization interface [polypeptide binding]; other site
1104326012386	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1104326012387	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1104326012388	DNA binding residues [nucleotide binding]
1104326012389	dimerization interface [polypeptide binding]; other site
1104326012390	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
1104326012391	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
1104326012392	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
1104326012393	putative active site [active]
1104326012394	putative metal binding site [ion binding]; other site
1104326012395	N-glycosyltransferase; Provisional; Region: PRK11204
1104326012396	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1104326012397	DXD motif; other site
1104326012398	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1104326012399	hemin storage system protein; Provisional; Region: hmsS; PRK14584
1104326012400	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1104326012401	active site
1104326012402	substrate binding site [chemical binding]; other site
1104326012403	ATP binding site [chemical binding]; other site
1104326012404	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1104326012405	CHAP domain; Region: CHAP; pfam05257
1104326012406	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1104326012407	putative S-transferase; Provisional; Region: PRK11752
1104326012408	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1104326012409	C-terminal domain interface [polypeptide binding]; other site
1104326012410	GSH binding site (G-site) [chemical binding]; other site
1104326012411	dimer interface [polypeptide binding]; other site
1104326012412	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1104326012413	dimer interface [polypeptide binding]; other site
1104326012414	N-terminal domain interface [polypeptide binding]; other site
1104326012415	active site
1104326012416	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
1104326012417	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1104326012418	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1104326012419	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1104326012420	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1104326012421	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1104326012422	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1104326012423	Metal-binding active site; metal-binding site
1104326012424	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1104326012425	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1104326012426	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326012427	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1104326012428	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326012429	dimerization interface [polypeptide binding]; other site
1104326012430	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326012431	dimer interface [polypeptide binding]; other site
1104326012432	putative CheW interface [polypeptide binding]; other site
1104326012433	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326012434	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326012435	active site
1104326012436	catalytic tetrad [active]
1104326012437	hypothetical protein; Provisional; Region: PRK05208
1104326012438	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1104326012439	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1104326012440	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1104326012441	cystathionine beta-lyase; Provisional; Region: PRK08114
1104326012442	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1104326012443	homodimer interface [polypeptide binding]; other site
1104326012444	substrate-cofactor binding pocket; other site
1104326012445	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326012446	catalytic residue [active]
1104326012447	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1104326012448	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1104326012449	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1104326012450	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326012451	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326012452	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326012453	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1104326012454	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1104326012455	dimer interface [polypeptide binding]; other site
1104326012456	active site
1104326012457	metal binding site [ion binding]; metal-binding site
1104326012458	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1104326012459	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1104326012460	active site
1104326012461	catalytic tetrad [active]
1104326012462	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1104326012463	potential frameshift: common BLAST hit: gi|365972088|ref|YP_004953649.1| protein YgiQ
1104326012464	Cation transport protein; Region: TrkH; cl17365
1104326012465	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1104326012466	FtsI repressor; Provisional; Region: PRK10883
1104326012467	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1104326012468	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1104326012469	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1104326012470	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1104326012471	putative acyl-acceptor binding pocket; other site
1104326012472	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1104326012473	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1104326012474	CAP-like domain; other site
1104326012475	active site
1104326012476	primary dimer interface [polypeptide binding]; other site
1104326012477	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1104326012478	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1104326012479	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1104326012480	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012481	active site
1104326012482	phosphorylation site [posttranslational modification]
1104326012483	intermolecular recognition site; other site
1104326012484	dimerization interface [polypeptide binding]; other site
1104326012485	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326012486	DNA binding site [nucleotide binding]
1104326012487	sensor protein QseC; Provisional; Region: PRK10337
1104326012488	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326012489	dimer interface [polypeptide binding]; other site
1104326012490	phosphorylation site [posttranslational modification]
1104326012491	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326012492	ATP binding site [chemical binding]; other site
1104326012493	Mg2+ binding site [ion binding]; other site
1104326012494	G-X-G motif; other site
1104326012495	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1104326012496	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1104326012497	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1104326012498	BON domain; Region: BON; pfam04972
1104326012499	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1104326012500	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1104326012501	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1104326012502	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cd04795
1104326012503	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1104326012504	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1104326012505	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1104326012506	intersubunit interface [polypeptide binding]; other site
1104326012507	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1104326012508	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326012509	ABC-ATPase subunit  interface; other site
1104326012510	dimer interface [polypeptide binding]; other site
1104326012511	putative PBP binding regions; other site
1104326012512	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1104326012513	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1104326012514	dimer interface [polypeptide binding]; other site
1104326012515	putative PBP binding regions; other site
1104326012516	ABC-ATPase subunit  interface; other site
1104326012517	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1104326012518	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1104326012519	Walker A/P-loop; other site
1104326012520	ATP binding site [chemical binding]; other site
1104326012521	Q-loop/lid; other site
1104326012522	ABC transporter signature motif; other site
1104326012523	Walker B; other site
1104326012524	D-loop; other site
1104326012525	H-loop/switch region; other site
1104326012526	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1104326012527	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326012528	N-terminal plug; other site
1104326012529	ligand-binding site [chemical binding]; other site
1104326012530	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1104326012531	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326012532	ATP binding site [chemical binding]; other site
1104326012533	Mg2+ binding site [ion binding]; other site
1104326012534	G-X-G motif; other site
1104326012535	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1104326012536	anchoring element; other site
1104326012537	dimer interface [polypeptide binding]; other site
1104326012538	ATP binding site [chemical binding]; other site
1104326012539	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1104326012540	active site
1104326012541	metal binding site [ion binding]; metal-binding site
1104326012542	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1104326012543	esterase YqiA; Provisional; Region: PRK11071
1104326012544	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1104326012545	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1104326012546	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1104326012547	active site
1104326012548	metal binding site [ion binding]; metal-binding site
1104326012549	hexamer interface [polypeptide binding]; other site
1104326012550	putative dehydrogenase; Provisional; Region: PRK11039
1104326012551	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1104326012552	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1104326012553	dimer interface [polypeptide binding]; other site
1104326012554	ADP-ribose binding site [chemical binding]; other site
1104326012555	active site
1104326012556	nudix motif; other site
1104326012557	metal binding site [ion binding]; metal-binding site
1104326012558	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1104326012559	hypothetical protein; Provisional; Region: PRK11653
1104326012560	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1104326012561	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1104326012562	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1104326012563	putative active site [active]
1104326012564	metal binding site [ion binding]; metal-binding site
1104326012565	zinc transporter ZupT; Provisional; Region: PRK04201
1104326012566	ZIP Zinc transporter; Region: Zip; pfam02535
1104326012567	Fimbrial protein; Region: Fimbrial; cl01416
1104326012568	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326012569	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326012570	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326012571	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326012572	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1104326012573	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326012574	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1104326012575	Fimbrial protein; Region: Fimbrial; pfam00419
1104326012576	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1104326012577	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1104326012578	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1104326012579	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1104326012580	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1104326012581	putative ribose interaction site [chemical binding]; other site
1104326012582	putative ADP binding site [chemical binding]; other site
1104326012583	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1104326012584	active site
1104326012585	nucleotide binding site [chemical binding]; other site
1104326012586	HIGH motif; other site
1104326012587	KMSKS motif; other site
1104326012588	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1104326012589	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1104326012590	metal binding triad; other site
1104326012591	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1104326012592	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1104326012593	metal binding triad; other site
1104326012594	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1104326012595	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1104326012596	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1104326012597	putative active site [active]
1104326012598	putative metal binding residues [ion binding]; other site
1104326012599	signature motif; other site
1104326012600	putative triphosphate binding site [ion binding]; other site
1104326012601	CHAD domain; Region: CHAD; pfam05235
1104326012602	SH3 domain-containing protein; Provisional; Region: PRK10884
1104326012603	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1104326012604	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1104326012605	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1104326012606	active site
1104326012607	NTP binding site [chemical binding]; other site
1104326012608	metal binding triad [ion binding]; metal-binding site
1104326012609	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1104326012610	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1104326012611	Zn2+ binding site [ion binding]; other site
1104326012612	Mg2+ binding site [ion binding]; other site
1104326012613	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1104326012614	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1104326012615	homooctamer interface [polypeptide binding]; other site
1104326012616	active site
1104326012617	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1104326012618	benzoate transport; Region: 2A0115; TIGR00895
1104326012619	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012620	putative substrate translocation pore; other site
1104326012621	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1104326012622	MarR family; Region: MarR; pfam01047
1104326012623	MarR family; Region: MarR_2; cl17246
1104326012624	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1104326012625	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1104326012626	UreD urease accessory protein; Region: UreD; cl00530
1104326012627	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
1104326012628	alpha-gamma subunit interface [polypeptide binding]; other site
1104326012629	beta-gamma subunit interface [polypeptide binding]; other site
1104326012630	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
1104326012631	gamma-beta subunit interface [polypeptide binding]; other site
1104326012632	alpha-beta subunit interface [polypeptide binding]; other site
1104326012633	urease subunit alpha; Reviewed; Region: ureC; PRK13207
1104326012634	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
1104326012635	subunit interactions [polypeptide binding]; other site
1104326012636	active site
1104326012637	flap region; other site
1104326012638	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
1104326012639	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
1104326012640	dimer interface [polypeptide binding]; other site
1104326012641	catalytic residues [active]
1104326012642	HupE / UreJ protein; Region: HupE_UreJ; pfam04955
1104326012643	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
1104326012644	UreF; Region: UreF; pfam01730
1104326012645	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1104326012646	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1104326012647	active site
1104326012648	catalytic residues [active]
1104326012649	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1104326012650	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
1104326012651	UGMP family protein; Validated; Region: PRK09604
1104326012652	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1104326012653	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1104326012654	DNA primase; Validated; Region: dnaG; PRK05667
1104326012655	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1104326012656	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1104326012657	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1104326012658	active site
1104326012659	metal binding site [ion binding]; metal-binding site
1104326012660	interdomain interaction site; other site
1104326012661	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1104326012662	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1104326012663	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1104326012664	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1104326012665	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1104326012666	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1104326012667	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326012668	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1104326012669	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326012670	DNA binding residues [nucleotide binding]
1104326012671	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1104326012672	active site
1104326012673	SUMO-1 interface [polypeptide binding]; other site
1104326012674	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1104326012675	tail protein; Provisional; Region: D; PHA02561
1104326012676	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1104326012677	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1104326012678	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1104326012679	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1104326012680	major tail tube protein; Provisional; Region: FII; PHA02600
1104326012681	major tail sheath protein; Provisional; Region: FI; PHA02560
1104326012682	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1104326012683	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1104326012684	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1104326012685	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1104326012686	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1104326012687	phage tail protein, P2 protein I family; Region: tail_P2_I; TIGR01634
1104326012688	baseplate assembly protein; Provisional; Region: J; PHA02568
1104326012689	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1104326012690	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1104326012691	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1104326012692	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1104326012693	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1104326012694	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1104326012695	catalytic residues [active]
1104326012696	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1104326012697	DinI-like family; Region: DinI; pfam06183
1104326012698	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1104326012699	DksA-like zinc finger domain containing protein; Region: PHA00080
1104326012700	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1104326012701	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1104326012702	integrase; Provisional; Region: int; PHA02601
1104326012703	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1104326012704	dimer interface [polypeptide binding]; other site
1104326012705	active site
1104326012706	catalytic residues [active]
1104326012707	Int/Topo IB signature motif; other site
1104326012708	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1104326012709	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326012710	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1104326012711	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326012712	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1104326012713	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326012714	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326012715	substrate binding pocket [chemical binding]; other site
1104326012716	membrane-bound complex binding site; other site
1104326012717	hinge residues; other site
1104326012718	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1104326012719	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326012720	substrate binding pocket [chemical binding]; other site
1104326012721	membrane-bound complex binding site; other site
1104326012722	hinge residues; other site
1104326012723	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326012724	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326012725	dimer interface [polypeptide binding]; other site
1104326012726	phosphorylation site [posttranslational modification]
1104326012727	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326012728	ATP binding site [chemical binding]; other site
1104326012729	Mg2+ binding site [ion binding]; other site
1104326012730	G-X-G motif; other site
1104326012731	Response regulator receiver domain; Region: Response_reg; pfam00072
1104326012732	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012733	active site
1104326012734	phosphorylation site [posttranslational modification]
1104326012735	intermolecular recognition site; other site
1104326012736	dimerization interface [polypeptide binding]; other site
1104326012737	Hpt domain; Region: Hpt; pfam01627
1104326012738	transcriptional regulator FimZ; Provisional; Region: PRK09935
1104326012739	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012740	active site
1104326012741	phosphorylation site [posttranslational modification]
1104326012742	intermolecular recognition site; other site
1104326012743	dimerization interface [polypeptide binding]; other site
1104326012744	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326012745	DNA binding residues [nucleotide binding]
1104326012746	S-Ribosylhomocysteinase (LuxS); Region: LuxS; cl00802
1104326012747	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1104326012748	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1104326012749	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1104326012750	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1104326012751	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1104326012752	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
1104326012753	Domain of unknown function (DUF4258); Region: DUF4258; pfam14076
1104326012754	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1104326012755	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1104326012756	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1104326012757	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
1104326012758	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326012759	active site
1104326012760	phosphorylation site [posttranslational modification]
1104326012761	intermolecular recognition site; other site
1104326012762	dimerization interface [polypeptide binding]; other site
1104326012763	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326012764	DNA binding residues [nucleotide binding]
1104326012765	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1104326012766	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1104326012767	SLBB domain; Region: SLBB; pfam10531
1104326012768	Chain length determinant protein; Region: Wzz; pfam02706
1104326012769	polysaccharide chain length determinant protein, PEP-CTERM locus subfamily; Region: pepcterm_ChnLen; TIGR03007
1104326012770	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1104326012771	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1104326012772	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1104326012773	P loop; other site
1104326012774	Nucleotide binding site [chemical binding]; other site
1104326012775	DTAP/Switch II; other site
1104326012776	Switch I; other site
1104326012777	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1104326012778	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1104326012779	HSP70 interaction site [polypeptide binding]; other site
1104326012780	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1104326012781	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1104326012782	FAD binding pocket [chemical binding]; other site
1104326012783	FAD binding motif [chemical binding]; other site
1104326012784	phosphate binding motif [ion binding]; other site
1104326012785	NAD binding pocket [chemical binding]; other site
1104326012786	Predicted transcriptional regulators [Transcription]; Region: COG1695
1104326012787	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1104326012788	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1104326012789	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1104326012790	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326012791	dimerization interface [polypeptide binding]; other site
1104326012792	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326012793	dimer interface [polypeptide binding]; other site
1104326012794	putative CheW interface [polypeptide binding]; other site
1104326012795	PAS domain; Region: PAS_9; pfam13426
1104326012796	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326012797	putative active site [active]
1104326012798	heme pocket [chemical binding]; other site
1104326012799	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1104326012800	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1104326012801	dimer interface [polypeptide binding]; other site
1104326012802	putative CheW interface [polypeptide binding]; other site
1104326012803	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1104326012804	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326012805	inhibitor-cofactor binding pocket; inhibition site
1104326012806	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326012807	catalytic residue [active]
1104326012808	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1104326012809	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326012810	non-specific DNA binding site [nucleotide binding]; other site
1104326012811	salt bridge; other site
1104326012812	sequence-specific DNA binding site [nucleotide binding]; other site
1104326012813	Cupin domain; Region: Cupin_2; pfam07883
1104326012814	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1104326012815	B3/4 domain; Region: B3_4; pfam03483
1104326012816	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1104326012817	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1104326012818	inhibitor site; inhibition site
1104326012819	active site
1104326012820	dimer interface [polypeptide binding]; other site
1104326012821	catalytic residue [active]
1104326012822	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1104326012823	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1104326012824	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1104326012825	putative active site; other site
1104326012826	catalytic residue [active]
1104326012827	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1104326012828	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1104326012829	ligand binding site [chemical binding]; other site
1104326012830	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326012831	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326012832	TM-ABC transporter signature motif; other site
1104326012833	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326012834	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326012835	TM-ABC transporter signature motif; other site
1104326012836	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1104326012837	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326012838	Walker A/P-loop; other site
1104326012839	ATP binding site [chemical binding]; other site
1104326012840	Q-loop/lid; other site
1104326012841	ABC transporter signature motif; other site
1104326012842	Walker B; other site
1104326012843	D-loop; other site
1104326012844	H-loop/switch region; other site
1104326012845	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326012846	transcriptional regulator LsrR; Provisional; Region: PRK15418
1104326012847	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1104326012848	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1104326012849	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1104326012850	putative N- and C-terminal domain interface [polypeptide binding]; other site
1104326012851	putative active site [active]
1104326012852	putative MgATP binding site [chemical binding]; other site
1104326012853	catalytic site [active]
1104326012854	metal binding site [ion binding]; metal-binding site
1104326012855	putative carbohydrate binding site [chemical binding]; other site
1104326012856	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1104326012857	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1104326012858	active site
1104326012859	FMN binding site [chemical binding]; other site
1104326012860	2,4-decadienoyl-CoA binding site; other site
1104326012861	catalytic residue [active]
1104326012862	4Fe-4S cluster binding site [ion binding]; other site
1104326012863	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1104326012864	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326012865	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1104326012866	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326012867	S-adenosylmethionine binding site [chemical binding]; other site
1104326012868	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1104326012869	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1104326012870	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1104326012871	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1104326012872	serine/threonine transporter SstT; Provisional; Region: PRK13628
1104326012873	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1104326012874	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1104326012875	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1104326012876	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1104326012877	Glucuronate isomerase; Region: UxaC; pfam02614
1104326012878	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1104326012879	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326012880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326012881	putative substrate translocation pore; other site
1104326012882	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1104326012883	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326012884	DNA-binding site [nucleotide binding]; DNA binding site
1104326012885	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1104326012886	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1104326012887	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1104326012888	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1104326012889	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1104326012890	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1104326012891	Predicted membrane protein [Function unknown]; Region: COG5393
1104326012892	YqjK-like protein; Region: YqjK; pfam13997
1104326012893	Predicted membrane protein [Function unknown]; Region: COG2259
1104326012894	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1104326012895	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1104326012896	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1104326012897	putative dimer interface [polypeptide binding]; other site
1104326012898	N-terminal domain interface [polypeptide binding]; other site
1104326012899	putative substrate binding pocket (H-site) [chemical binding]; other site
1104326012900	Predicted membrane protein [Function unknown]; Region: COG3152
1104326012901	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326012902	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1104326012903	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326012904	dimerization interface [polypeptide binding]; other site
1104326012905	Pirin-related protein [General function prediction only]; Region: COG1741
1104326012906	Pirin; Region: Pirin; pfam02678
1104326012907	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1104326012908	dimer interface [polypeptide binding]; other site
1104326012909	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1104326012910	Pyruvate formate lyase 1; Region: PFL1; cd01678
1104326012911	coenzyme A binding site [chemical binding]; other site
1104326012912	active site
1104326012913	catalytic residues [active]
1104326012914	glycine loop; other site
1104326012915	propionate/acetate kinase; Provisional; Region: PRK12379
1104326012916	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1104326012917	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1104326012918	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1104326012919	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1104326012920	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1104326012921	tetramer interface [polypeptide binding]; other site
1104326012922	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326012923	catalytic residue [active]
1104326012924	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1104326012925	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326012926	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1104326012927	putative substrate binding pocket [chemical binding]; other site
1104326012928	putative dimerization interface [polypeptide binding]; other site
1104326012929	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1104326012930	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1104326012931	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1104326012932	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1104326012933	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1104326012934	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1104326012935	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
1104326012936	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1104326012937	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326012938	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
1104326012939	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1104326012940	active site
1104326012941	phosphorylation site [posttranslational modification]
1104326012942	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1104326012943	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1104326012944	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1104326012945	active pocket/dimerization site; other site
1104326012946	active site
1104326012947	phosphorylation site [posttranslational modification]
1104326012948	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1104326012949	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1104326012950	active site
1104326012951	dimer interface [polypeptide binding]; other site
1104326012952	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
1104326012953	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1104326012954	dimer interface [polypeptide binding]; other site
1104326012955	active site
1104326012956	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
1104326012957	putative active site [active]
1104326012958	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1104326012959	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1104326012960	intersubunit interface [polypeptide binding]; other site
1104326012961	active site
1104326012962	zinc binding site [ion binding]; other site
1104326012963	Na+ binding site [ion binding]; other site
1104326012964	Melibiase; Region: Melibiase; pfam02065
1104326012965	Fic family protein [Function unknown]; Region: COG3177
1104326012966	Fic/DOC family; Region: Fic; pfam02661
1104326012967	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1104326012968	non-specific DNA interactions [nucleotide binding]; other site
1104326012969	DNA binding site [nucleotide binding]
1104326012970	sequence specific DNA binding site [nucleotide binding]; other site
1104326012971	putative cAMP binding site [chemical binding]; other site
1104326012972	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1104326012973	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1104326012974	putative SAM binding site [chemical binding]; other site
1104326012975	putative homodimer interface [polypeptide binding]; other site
1104326012976	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1104326012977	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1104326012978	putative ligand binding site [chemical binding]; other site
1104326012979	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
1104326012980	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1104326012981	dimer interface [polypeptide binding]; other site
1104326012982	active site
1104326012983	outer membrane lipoprotein; Provisional; Region: PRK11023
1104326012984	BON domain; Region: BON; pfam04972
1104326012985	BON domain; Region: BON; pfam04972
1104326012986	Predicted permease; Region: DUF318; pfam03773
1104326012987	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1104326012988	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1104326012989	NAD binding site [chemical binding]; other site
1104326012990	active site
1104326012991	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1104326012992	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1104326012993	proposed catalytic triad [active]
1104326012994	conserved cys residue [active]
1104326012995	hypothetical protein; Provisional; Region: PRK03467
1104326012996	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1104326012997	GIY-YIG motif/motif A; other site
1104326012998	putative active site [active]
1104326012999	putative metal binding site [ion binding]; other site
1104326013000	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1104326013001	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326013002	Coenzyme A binding pocket [chemical binding]; other site
1104326013003	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1104326013004	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1104326013005	Peptidase family U32; Region: Peptidase_U32; pfam01136
1104326013006	putative protease; Provisional; Region: PRK15447
1104326013007	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1104326013008	hypothetical protein; Provisional; Region: PRK10508
1104326013009	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1104326013010	tryptophan permease; Provisional; Region: PRK10483
1104326013011	aromatic amino acid transport protein; Region: araaP; TIGR00837
1104326013012	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1104326013013	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1104326013014	ATP binding site [chemical binding]; other site
1104326013015	Mg++ binding site [ion binding]; other site
1104326013016	motif III; other site
1104326013017	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326013018	nucleotide binding region [chemical binding]; other site
1104326013019	ATP-binding site [chemical binding]; other site
1104326013020	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1104326013021	putative RNA binding site [nucleotide binding]; other site
1104326013022	lipoprotein NlpI; Provisional; Region: PRK11189
1104326013023	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326013024	binding surface
1104326013025	TPR motif; other site
1104326013026	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1104326013027	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1104326013028	RNase E interface [polypeptide binding]; other site
1104326013029	trimer interface [polypeptide binding]; other site
1104326013030	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1104326013031	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1104326013032	RNase E interface [polypeptide binding]; other site
1104326013033	trimer interface [polypeptide binding]; other site
1104326013034	active site
1104326013035	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1104326013036	putative nucleic acid binding region [nucleotide binding]; other site
1104326013037	G-X-X-G motif; other site
1104326013038	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1104326013039	RNA binding site [nucleotide binding]; other site
1104326013040	domain interface; other site
1104326013041	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1104326013042	16S/18S rRNA binding site [nucleotide binding]; other site
1104326013043	S13e-L30e interaction site [polypeptide binding]; other site
1104326013044	25S rRNA binding site [nucleotide binding]; other site
1104326013045	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1104326013046	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1104326013047	RNA binding site [nucleotide binding]; other site
1104326013048	active site
1104326013049	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1104326013050	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1104326013051	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1104326013052	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1104326013053	translation initiation factor IF-2; Region: IF-2; TIGR00487
1104326013054	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1104326013055	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1104326013056	G1 box; other site
1104326013057	putative GEF interaction site [polypeptide binding]; other site
1104326013058	GTP/Mg2+ binding site [chemical binding]; other site
1104326013059	Switch I region; other site
1104326013060	G2 box; other site
1104326013061	G3 box; other site
1104326013062	Switch II region; other site
1104326013063	G4 box; other site
1104326013064	G5 box; other site
1104326013065	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1104326013066	Translation-initiation factor 2; Region: IF-2; pfam11987
1104326013067	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1104326013068	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1104326013069	NusA N-terminal domain; Region: NusA_N; pfam08529
1104326013070	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1104326013071	RNA binding site [nucleotide binding]; other site
1104326013072	homodimer interface [polypeptide binding]; other site
1104326013073	NusA-like KH domain; Region: KH_5; pfam13184
1104326013074	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1104326013075	G-X-X-G motif; other site
1104326013076	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1104326013077	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1104326013078	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1104326013079	Sm and related proteins; Region: Sm_like; cl00259
1104326013080	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1104326013081	putative oligomer interface [polypeptide binding]; other site
1104326013082	putative RNA binding site [nucleotide binding]; other site
1104326013083	argininosuccinate synthase; Validated; Region: PRK05370
1104326013084	argininosuccinate synthase; Provisional; Region: PRK13820
1104326013085	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1104326013086	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1104326013087	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1104326013088	active site
1104326013089	substrate binding site [chemical binding]; other site
1104326013090	metal binding site [ion binding]; metal-binding site
1104326013091	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1104326013092	dihydropteroate synthase; Region: DHPS; TIGR01496
1104326013093	substrate binding pocket [chemical binding]; other site
1104326013094	dimer interface [polypeptide binding]; other site
1104326013095	inhibitor binding site; inhibition site
1104326013096	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1104326013097	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326013098	Walker A motif; other site
1104326013099	ATP binding site [chemical binding]; other site
1104326013100	Walker B motif; other site
1104326013101	arginine finger; other site
1104326013102	Peptidase family M41; Region: Peptidase_M41; pfam01434
1104326013103	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1104326013104	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326013105	S-adenosylmethionine binding site [chemical binding]; other site
1104326013106	RNA-binding protein YhbY; Provisional; Region: PRK10343
1104326013107	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1104326013108	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1104326013109	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1104326013110	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1104326013111	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1104326013112	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1104326013113	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326013114	active site
1104326013115	phosphorylation site [posttranslational modification]
1104326013116	intermolecular recognition site; other site
1104326013117	dimerization interface [polypeptide binding]; other site
1104326013118	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326013119	DNA binding site [nucleotide binding]
1104326013120	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1104326013121	HAMP domain; Region: HAMP; pfam00672
1104326013122	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326013123	dimer interface [polypeptide binding]; other site
1104326013124	phosphorylation site [posttranslational modification]
1104326013125	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326013126	ATP binding site [chemical binding]; other site
1104326013127	Mg2+ binding site [ion binding]; other site
1104326013128	G-X-G motif; other site
1104326013129	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1104326013130	GTP1/OBG; Region: GTP1_OBG; pfam01018
1104326013131	Obg GTPase; Region: Obg; cd01898
1104326013132	G1 box; other site
1104326013133	GTP/Mg2+ binding site [chemical binding]; other site
1104326013134	Switch I region; other site
1104326013135	G2 box; other site
1104326013136	G3 box; other site
1104326013137	Switch II region; other site
1104326013138	G4 box; other site
1104326013139	G5 box; other site
1104326013140	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1104326013141	EamA-like transporter family; Region: EamA; pfam00892
1104326013142	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1104326013143	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1104326013144	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1104326013145	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1104326013146	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1104326013147	substrate binding pocket [chemical binding]; other site
1104326013148	chain length determination region; other site
1104326013149	substrate-Mg2+ binding site; other site
1104326013150	catalytic residues [active]
1104326013151	aspartate-rich region 1; other site
1104326013152	active site lid residues [active]
1104326013153	aspartate-rich region 2; other site
1104326013154	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1104326013155	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1104326013156	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1104326013157	hinge; other site
1104326013158	active site
1104326013159	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1104326013160	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1104326013161	anti sigma factor interaction site; other site
1104326013162	regulatory phosphorylation site [posttranslational modification]; other site
1104326013163	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1104326013164	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1104326013165	mce related protein; Region: MCE; pfam02470
1104326013166	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1104326013167	conserved hypothetical integral membrane protein; Region: TIGR00056
1104326013168	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1104326013169	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1104326013170	Walker A/P-loop; other site
1104326013171	ATP binding site [chemical binding]; other site
1104326013172	Q-loop/lid; other site
1104326013173	ABC transporter signature motif; other site
1104326013174	Walker B; other site
1104326013175	D-loop; other site
1104326013176	H-loop/switch region; other site
1104326013177	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1104326013178	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1104326013179	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1104326013180	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1104326013181	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1104326013182	putative active site [active]
1104326013183	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1104326013184	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1104326013185	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1104326013186	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1104326013187	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1104326013188	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1104326013189	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1104326013190	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1104326013191	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1104326013192	Walker A/P-loop; other site
1104326013193	ATP binding site [chemical binding]; other site
1104326013194	Q-loop/lid; other site
1104326013195	ABC transporter signature motif; other site
1104326013196	Walker B; other site
1104326013197	D-loop; other site
1104326013198	H-loop/switch region; other site
1104326013199	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1104326013200	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1104326013201	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1104326013202	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1104326013203	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1104326013204	30S subunit binding site; other site
1104326013205	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1104326013206	active site
1104326013207	phosphorylation site [posttranslational modification]
1104326013208	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1104326013209	AAA domain; Region: AAA_18; pfam13238
1104326013210	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1104326013211	dimerization domain swap beta strand [polypeptide binding]; other site
1104326013212	regulatory protein interface [polypeptide binding]; other site
1104326013213	active site
1104326013214	regulatory phosphorylation site [posttranslational modification]; other site
1104326013215	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1104326013216	Transglycosylase; Region: Transgly; cl17702
1104326013217	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1104326013218	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1104326013219	conserved cys residue [active]
1104326013220	potential frameshift: common BLAST hit: gi|296104922|ref|YP_003615068.1| aerobic respiration control sensor protein ArcB
1104326013221	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1104326013222	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1104326013223	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1104326013224	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1104326013225	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1104326013226	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1104326013227	interface (dimer of trimers) [polypeptide binding]; other site
1104326013228	Substrate-binding/catalytic site; other site
1104326013229	Zn-binding sites [ion binding]; other site
1104326013230	DNA polymerase III subunit chi; Validated; Region: PRK05728
1104326013231	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1104326013232	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1104326013233	HIGH motif; other site
1104326013234	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1104326013235	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1104326013236	active site
1104326013237	KMSKS motif; other site
1104326013238	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1104326013239	tRNA binding surface [nucleotide binding]; other site
1104326013240	anticodon binding site; other site
1104326013241	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1104326013242	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1104326013243	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326013244	Coenzyme A binding pocket [chemical binding]; other site
1104326013245	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1104326013246	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1104326013247	putative NAD(P) binding site [chemical binding]; other site
1104326013248	putative substrate binding site [chemical binding]; other site
1104326013249	catalytic Zn binding site [ion binding]; other site
1104326013250	structural Zn binding site [ion binding]; other site
1104326013251	dimer interface [polypeptide binding]; other site
1104326013252	dihydroxyacetone kinase, ATP-dependent; Region: dak_ATP; TIGR02361
1104326013253	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
1104326013254	DAK2 domain; Region: Dak2; pfam02734
1104326013255	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1104326013256	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1104326013257	Walker A motif; other site
1104326013258	ATP binding site [chemical binding]; other site
1104326013259	radical SAM protein, TIGR01212 family; Region: TIGR01212
1104326013260	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1104326013261	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1104326013262	active site
1104326013263	dimer interface [polypeptide binding]; other site
1104326013264	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1104326013265	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1104326013266	active site
1104326013267	FMN binding site [chemical binding]; other site
1104326013268	substrate binding site [chemical binding]; other site
1104326013269	3Fe-4S cluster binding site [ion binding]; other site
1104326013270	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1104326013271	domain interface; other site
1104326013272	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1104326013273	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326013274	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326013275	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1104326013276	putative sialic acid transporter; Provisional; Region: PRK03893
1104326013277	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326013278	putative substrate translocation pore; other site
1104326013279	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1104326013280	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1104326013281	inhibitor site; inhibition site
1104326013282	active site
1104326013283	dimer interface [polypeptide binding]; other site
1104326013284	catalytic residue [active]
1104326013285	transcriptional regulator NanR; Provisional; Region: PRK03837
1104326013286	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326013287	DNA-binding site [nucleotide binding]; DNA binding site
1104326013288	FCD domain; Region: FCD; pfam07729
1104326013289	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1104326013290	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1104326013291	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1104326013292	C-terminal domain interface [polypeptide binding]; other site
1104326013293	putative GSH binding site (G-site) [chemical binding]; other site
1104326013294	dimer interface [polypeptide binding]; other site
1104326013295	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1104326013296	dimer interface [polypeptide binding]; other site
1104326013297	N-terminal domain interface [polypeptide binding]; other site
1104326013298	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1104326013299	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1104326013300	23S rRNA interface [nucleotide binding]; other site
1104326013301	L3 interface [polypeptide binding]; other site
1104326013302	Predicted ATPase [General function prediction only]; Region: COG1485
1104326013303	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1104326013304	hypothetical protein; Provisional; Region: PRK11677
1104326013305	serine endoprotease; Provisional; Region: PRK10139
1104326013306	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1104326013307	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1104326013308	protein binding site [polypeptide binding]; other site
1104326013309	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1104326013310	serine endoprotease; Provisional; Region: PRK10898
1104326013311	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1104326013312	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1104326013313	malate dehydrogenase; Provisional; Region: PRK05086
1104326013314	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1104326013315	NAD binding site [chemical binding]; other site
1104326013316	dimerization interface [polypeptide binding]; other site
1104326013317	Substrate binding site [chemical binding]; other site
1104326013318	arginine repressor; Provisional; Region: PRK05066
1104326013319	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1104326013320	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1104326013321	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326013322	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1104326013323	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1104326013324	RNAase interaction site [polypeptide binding]; other site
1104326013325	succinic semialdehyde dehydrogenase; Region: PLN02278
1104326013326	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1104326013327	tetramerization interface [polypeptide binding]; other site
1104326013328	NAD(P) binding site [chemical binding]; other site
1104326013329	catalytic residues [active]
1104326013330	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1104326013331	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1104326013332	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1104326013333	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326013334	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326013335	efflux system membrane protein; Provisional; Region: PRK11594
1104326013336	transcriptional regulator; Provisional; Region: PRK10632
1104326013337	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326013338	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1104326013339	putative effector binding pocket; other site
1104326013340	dimerization interface [polypeptide binding]; other site
1104326013341	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
1104326013342	protease TldD; Provisional; Region: tldD; PRK10735
1104326013343	hypothetical protein; Provisional; Region: PRK10899
1104326013344	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1104326013345	ribonuclease G; Provisional; Region: PRK11712
1104326013346	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1104326013347	homodimer interface [polypeptide binding]; other site
1104326013348	oligonucleotide binding site [chemical binding]; other site
1104326013349	Maf-like protein; Region: Maf; pfam02545
1104326013350	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1104326013351	active site
1104326013352	dimer interface [polypeptide binding]; other site
1104326013353	rod shape-determining protein MreD; Provisional; Region: PRK11060
1104326013354	rod shape-determining protein MreC; Region: mreC; TIGR00219
1104326013355	rod shape-determining protein MreC; Region: MreC; pfam04085
1104326013356	rod shape-determining protein MreB; Provisional; Region: PRK13927
1104326013357	MreB and similar proteins; Region: MreB_like; cd10225
1104326013358	nucleotide binding site [chemical binding]; other site
1104326013359	Mg binding site [ion binding]; other site
1104326013360	putative protofilament interaction site [polypeptide binding]; other site
1104326013361	RodZ interaction site [polypeptide binding]; other site
1104326013362	regulatory protein CsrD; Provisional; Region: PRK11059
1104326013363	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326013364	metal binding site [ion binding]; metal-binding site
1104326013365	active site
1104326013366	I-site; other site
1104326013367	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326013368	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1104326013369	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1104326013370	NADP binding site [chemical binding]; other site
1104326013371	dimer interface [polypeptide binding]; other site
1104326013372	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1104326013373	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1104326013374	Moco binding site; other site
1104326013375	metal coordination site [ion binding]; other site
1104326013376	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1104326013377	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1104326013378	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1104326013379	trimer interface [polypeptide binding]; other site
1104326013380	active site
1104326013381	dimer interface [polypeptide binding]; other site
1104326013382	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1104326013383	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1104326013384	carboxyltransferase (CT) interaction site; other site
1104326013385	biotinylation site [posttranslational modification]; other site
1104326013386	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1104326013387	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1104326013388	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1104326013389	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1104326013390	hypothetical protein; Provisional; Region: PRK10633
1104326013391	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1104326013392	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1104326013393	Na binding site [ion binding]; other site
1104326013394	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1104326013395	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1104326013396	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1104326013397	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1104326013398	FMN binding site [chemical binding]; other site
1104326013399	active site
1104326013400	catalytic residues [active]
1104326013401	substrate binding site [chemical binding]; other site
1104326013402	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1104326013403	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1104326013404	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1104326013405	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1104326013406	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1104326013407	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1104326013408	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1104326013409	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326013410	metal binding site [ion binding]; metal-binding site
1104326013411	active site
1104326013412	I-site; other site
1104326013413	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326013414	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1104326013415	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326013416	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1104326013417	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1104326013418	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326013419	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326013420	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1104326013421	Protein export membrane protein; Region: SecD_SecF; cl14618
1104326013422	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326013423	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1104326013424	substrate binding pocket [chemical binding]; other site
1104326013425	membrane-bound complex binding site; other site
1104326013426	hinge residues; other site
1104326013427	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
1104326013428	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326013429	conserved gate region; other site
1104326013430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326013431	dimer interface [polypeptide binding]; other site
1104326013432	ABC-ATPase subunit interface; other site
1104326013433	putative PBP binding loops; other site
1104326013434	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1104326013435	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326013436	dimer interface [polypeptide binding]; other site
1104326013437	conserved gate region; other site
1104326013438	putative PBP binding loops; other site
1104326013439	ABC-ATPase subunit interface; other site
1104326013440	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1104326013441	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1104326013442	Walker A/P-loop; other site
1104326013443	ATP binding site [chemical binding]; other site
1104326013444	Q-loop/lid; other site
1104326013445	ABC transporter signature motif; other site
1104326013446	Walker B; other site
1104326013447	D-loop; other site
1104326013448	H-loop/switch region; other site
1104326013449	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1104326013450	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1104326013451	trimer interface [polypeptide binding]; other site
1104326013452	putative metal binding site [ion binding]; other site
1104326013453	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1104326013454	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1104326013455	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1104326013456	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1104326013457	shikimate binding site; other site
1104326013458	NAD(P) binding site [chemical binding]; other site
1104326013459	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1104326013460	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1104326013461	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1104326013462	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1104326013463	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1104326013464	hypothetical protein; Validated; Region: PRK03430
1104326013465	hypothetical protein; Provisional; Region: PRK10736
1104326013466	DNA protecting protein DprA; Region: dprA; TIGR00732
1104326013467	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1104326013468	active site
1104326013469	catalytic residues [active]
1104326013470	metal binding site [ion binding]; metal-binding site
1104326013471	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1104326013472	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1104326013473	putative active site [active]
1104326013474	substrate binding site [chemical binding]; other site
1104326013475	putative cosubstrate binding site; other site
1104326013476	catalytic site [active]
1104326013477	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1104326013478	substrate binding site [chemical binding]; other site
1104326013479	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1104326013480	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1104326013481	putative RNA binding site [nucleotide binding]; other site
1104326013482	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326013483	S-adenosylmethionine binding site [chemical binding]; other site
1104326013484	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1104326013485	TrkA-N domain; Region: TrkA_N; pfam02254
1104326013486	TrkA-C domain; Region: TrkA_C; pfam02080
1104326013487	TrkA-N domain; Region: TrkA_N; pfam02254
1104326013488	TrkA-C domain; Region: TrkA_C; pfam02080
1104326013489	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1104326013490	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
1104326013491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1104326013492	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1104326013493	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1104326013494	DNA binding residues [nucleotide binding]
1104326013495	dimer interface [polypeptide binding]; other site
1104326013496	metal binding site [ion binding]; metal-binding site
1104326013497	hypothetical protein; Provisional; Region: PRK10203
1104326013498	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1104326013499	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1104326013500	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1104326013501	alphaNTD homodimer interface [polypeptide binding]; other site
1104326013502	alphaNTD - beta interaction site [polypeptide binding]; other site
1104326013503	alphaNTD - beta' interaction site [polypeptide binding]; other site
1104326013504	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1104326013505	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1104326013506	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1104326013507	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326013508	RNA binding surface [nucleotide binding]; other site
1104326013509	30S ribosomal protein S11; Validated; Region: PRK05309
1104326013510	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1104326013511	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1104326013512	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1104326013513	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1104326013514	SecY translocase; Region: SecY; pfam00344
1104326013515	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1104326013516	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1104326013517	23S rRNA binding site [nucleotide binding]; other site
1104326013518	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1104326013519	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1104326013520	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1104326013521	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1104326013522	23S rRNA interface [nucleotide binding]; other site
1104326013523	5S rRNA interface [nucleotide binding]; other site
1104326013524	L27 interface [polypeptide binding]; other site
1104326013525	L5 interface [polypeptide binding]; other site
1104326013526	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1104326013527	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1104326013528	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1104326013529	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1104326013530	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1104326013531	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1104326013532	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1104326013533	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1104326013534	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1104326013535	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1104326013536	RNA binding site [nucleotide binding]; other site
1104326013537	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1104326013538	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1104326013539	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1104326013540	23S rRNA interface [nucleotide binding]; other site
1104326013541	putative translocon interaction site; other site
1104326013542	signal recognition particle (SRP54) interaction site; other site
1104326013543	L23 interface [polypeptide binding]; other site
1104326013544	trigger factor interaction site; other site
1104326013545	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1104326013546	23S rRNA interface [nucleotide binding]; other site
1104326013547	5S rRNA interface [nucleotide binding]; other site
1104326013548	putative antibiotic binding site [chemical binding]; other site
1104326013549	L25 interface [polypeptide binding]; other site
1104326013550	L27 interface [polypeptide binding]; other site
1104326013551	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1104326013552	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1104326013553	G-X-X-G motif; other site
1104326013554	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1104326013555	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1104326013556	protein-rRNA interface [nucleotide binding]; other site
1104326013557	putative translocon binding site; other site
1104326013558	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1104326013559	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1104326013560	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1104326013561	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1104326013562	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1104326013563	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1104326013564	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1104326013565	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1104326013566	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1104326013567	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1104326013568	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1104326013569	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1104326013570	heme binding site [chemical binding]; other site
1104326013571	ferroxidase pore; other site
1104326013572	ferroxidase diiron center [ion binding]; other site
1104326013573	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1104326013574	elongation factor Tu; Reviewed; Region: PRK00049
1104326013575	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1104326013576	G1 box; other site
1104326013577	GEF interaction site [polypeptide binding]; other site
1104326013578	GTP/Mg2+ binding site [chemical binding]; other site
1104326013579	Switch I region; other site
1104326013580	G2 box; other site
1104326013581	G3 box; other site
1104326013582	Switch II region; other site
1104326013583	G4 box; other site
1104326013584	G5 box; other site
1104326013585	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1104326013586	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1104326013587	Antibiotic Binding Site [chemical binding]; other site
1104326013588	elongation factor G; Reviewed; Region: PRK00007
1104326013589	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1104326013590	G1 box; other site
1104326013591	putative GEF interaction site [polypeptide binding]; other site
1104326013592	GTP/Mg2+ binding site [chemical binding]; other site
1104326013593	Switch I region; other site
1104326013594	G2 box; other site
1104326013595	G3 box; other site
1104326013596	Switch II region; other site
1104326013597	G4 box; other site
1104326013598	G5 box; other site
1104326013599	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1104326013600	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1104326013601	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1104326013602	30S ribosomal protein S7; Validated; Region: PRK05302
1104326013603	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1104326013604	S17 interaction site [polypeptide binding]; other site
1104326013605	S8 interaction site; other site
1104326013606	16S rRNA interaction site [nucleotide binding]; other site
1104326013607	streptomycin interaction site [chemical binding]; other site
1104326013608	23S rRNA interaction site [nucleotide binding]; other site
1104326013609	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1104326013610	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1104326013611	sulfur relay protein TusC; Validated; Region: PRK00211
1104326013612	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1104326013613	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1104326013614	YheO-like PAS domain; Region: PAS_6; pfam08348
1104326013615	HTH domain; Region: HTH_22; pfam13309
1104326013616	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1104326013617	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1104326013618	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1104326013619	phi X174 lysis protein; Provisional; Region: PRK02793
1104326013620	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1104326013621	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1104326013622	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1104326013623	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1104326013624	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1104326013625	TrkA-N domain; Region: TrkA_N; pfam02254
1104326013626	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1104326013627	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1104326013628	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326013629	Walker A/P-loop; other site
1104326013630	ATP binding site [chemical binding]; other site
1104326013631	Q-loop/lid; other site
1104326013632	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326013633	ABC transporter signature motif; other site
1104326013634	Walker B; other site
1104326013635	D-loop; other site
1104326013636	ABC transporter; Region: ABC_tran_2; pfam12848
1104326013637	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1104326013638	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1104326013639	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326013640	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326013641	The C-terminal substrate-binding domian of LysR-type transcriptional regulator MdcR, which involved in the malonate catabolism contains the type 2 periplasmic binding fold; Region: PBP2_MdcR; cd08416
1104326013642	putative dimerization interface [polypeptide binding]; other site
1104326013643	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1104326013644	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
1104326013645	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293
1104326013646	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
1104326013647	he Auxin Efflux Carrier (AEC) Family; Region: 2a69; TIGR00946
1104326013648	Malonate decarboxylase gamma subunit (MdcE); Region: MdcE; pfam06833
1104326013649	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189
1104326013650	Malonate decarboxylase delta subunit (MdcD); Region: ACP; cl06082
1104326013651	triphosphoribosyl-dephospho-CoA synthase; Validated; Region: PRK01237
1104326013652	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
1104326013653	Coenzyme A transferase; Region: CoA_trans; cl17247
1104326013654	putative hydrolase; Provisional; Region: PRK10985
1104326013655	hypothetical protein; Provisional; Region: PRK04966
1104326013656	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1104326013657	active site
1104326013658	hypothetical protein; Provisional; Region: PRK10738
1104326013659	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1104326013660	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1104326013661	ligand binding site [chemical binding]; other site
1104326013662	flexible hinge region; other site
1104326013663	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1104326013664	putative switch regulator; other site
1104326013665	non-specific DNA interactions [nucleotide binding]; other site
1104326013666	DNA binding site [nucleotide binding]
1104326013667	sequence specific DNA binding site [nucleotide binding]; other site
1104326013668	putative cAMP binding site [chemical binding]; other site
1104326013669	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1104326013670	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1104326013671	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1104326013672	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1104326013673	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326013674	inhibitor-cofactor binding pocket; inhibition site
1104326013675	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326013676	catalytic residue [active]
1104326013677	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1104326013678	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1104326013679	glutamine binding [chemical binding]; other site
1104326013680	catalytic triad [active]
1104326013681	hypothetical protein; Provisional; Region: PRK10204
1104326013682	Fic/DOC family; Region: Fic; cl00960
1104326013683	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1104326013684	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1104326013685	substrate binding site [chemical binding]; other site
1104326013686	putative transporter; Provisional; Region: PRK03699
1104326013687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326013688	putative substrate translocation pore; other site
1104326013689	cytosine deaminase; Provisional; Region: PRK09230
1104326013690	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1104326013691	active site
1104326013692	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1104326013693	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326013694	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1104326013695	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1104326013696	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1104326013697	siroheme synthase; Provisional; Region: cysG; PRK10637
1104326013698	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1104326013699	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1104326013700	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1104326013701	active site
1104326013702	SAM binding site [chemical binding]; other site
1104326013703	homodimer interface [polypeptide binding]; other site
1104326013704	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1104326013705	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1104326013706	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1104326013707	active site
1104326013708	HIGH motif; other site
1104326013709	dimer interface [polypeptide binding]; other site
1104326013710	KMSKS motif; other site
1104326013711	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1104326013712	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326013713	motif II; other site
1104326013714	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1104326013715	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1104326013716	substrate binding site [chemical binding]; other site
1104326013717	hexamer interface [polypeptide binding]; other site
1104326013718	metal binding site [ion binding]; metal-binding site
1104326013719	DNA adenine methylase; Provisional; Region: PRK10904
1104326013720	cell division protein DamX; Validated; Region: PRK10905
1104326013721	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1104326013722	active site
1104326013723	dimer interface [polypeptide binding]; other site
1104326013724	metal binding site [ion binding]; metal-binding site
1104326013725	shikimate kinase; Reviewed; Region: aroK; PRK00131
1104326013726	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1104326013727	ADP binding site [chemical binding]; other site
1104326013728	magnesium binding site [ion binding]; other site
1104326013729	putative shikimate binding site; other site
1104326013730	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1104326013731	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1104326013732	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1104326013733	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1104326013734	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1104326013735	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1104326013736	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1104326013737	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1104326013738	Transglycosylase; Region: Transgly; pfam00912
1104326013739	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1104326013740	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1104326013741	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1104326013742	ADP-ribose binding site [chemical binding]; other site
1104326013743	dimer interface [polypeptide binding]; other site
1104326013744	active site
1104326013745	nudix motif; other site
1104326013746	metal binding site [ion binding]; metal-binding site
1104326013747	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1104326013748	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1104326013749	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326013750	motif II; other site
1104326013751	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1104326013752	RNA binding surface [nucleotide binding]; other site
1104326013753	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1104326013754	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1104326013755	dimerization interface [polypeptide binding]; other site
1104326013756	domain crossover interface; other site
1104326013757	redox-dependent activation switch; other site
1104326013758	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1104326013759	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1104326013760	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1104326013761	active site
1104326013762	substrate-binding site [chemical binding]; other site
1104326013763	metal-binding site [ion binding]
1104326013764	ATP binding site [chemical binding]; other site
1104326013765	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1104326013766	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326013767	dimerization interface [polypeptide binding]; other site
1104326013768	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326013769	dimer interface [polypeptide binding]; other site
1104326013770	phosphorylation site [posttranslational modification]
1104326013771	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326013772	ATP binding site [chemical binding]; other site
1104326013773	G-X-G motif; other site
1104326013774	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1104326013775	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326013776	active site
1104326013777	phosphorylation site [posttranslational modification]
1104326013778	intermolecular recognition site; other site
1104326013779	dimerization interface [polypeptide binding]; other site
1104326013780	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326013781	DNA binding site [nucleotide binding]
1104326013782	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1104326013783	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1104326013784	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1104326013785	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1104326013786	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1104326013787	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1104326013788	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1104326013789	RNA binding site [nucleotide binding]; other site
1104326013790	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1104326013791	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1104326013792	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1104326013793	G1 box; other site
1104326013794	GTP/Mg2+ binding site [chemical binding]; other site
1104326013795	Switch I region; other site
1104326013796	G2 box; other site
1104326013797	G3 box; other site
1104326013798	Switch II region; other site
1104326013799	G4 box; other site
1104326013800	G5 box; other site
1104326013801	Nucleoside recognition; Region: Gate; pfam07670
1104326013802	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1104326013803	Nucleoside recognition; Region: Gate; pfam07670
1104326013804	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1104326013805	carboxylesterase BioH; Provisional; Region: PRK10349
1104326013806	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1104326013807	DNA utilization protein GntX; Provisional; Region: PRK11595
1104326013808	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1104326013809	active site
1104326013810	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1104326013811	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1104326013812	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1104326013813	high-affinity gluconate transporter; Provisional; Region: PRK14984
1104326013814	gluconate transporter; Region: gntP; TIGR00791
1104326013815	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1104326013816	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
1104326013817	maltodextrin phosphorylase; Provisional; Region: PRK14985
1104326013818	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1104326013819	active site pocket [active]
1104326013820	transcriptional regulator MalT; Provisional; Region: PRK04841
1104326013821	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326013822	DNA binding residues [nucleotide binding]
1104326013823	dimerization interface [polypeptide binding]; other site
1104326013824	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1104326013825	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1104326013826	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1104326013827	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1104326013828	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1104326013829	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1104326013830	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1104326013831	active site residue [active]
1104326013832	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1104326013833	glycogen phosphorylase; Provisional; Region: PRK14986
1104326013834	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1104326013835	homodimer interface [polypeptide binding]; other site
1104326013836	active site pocket [active]
1104326013837	glycogen synthase; Provisional; Region: glgA; PRK00654
1104326013838	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1104326013839	ADP-binding pocket [chemical binding]; other site
1104326013840	homodimer interface [polypeptide binding]; other site
1104326013841	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1104326013842	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1104326013843	ligand binding site; other site
1104326013844	oligomer interface; other site
1104326013845	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1104326013846	dimer interface [polypeptide binding]; other site
1104326013847	N-terminal domain interface [polypeptide binding]; other site
1104326013848	sulfate 1 binding site; other site
1104326013849	glycogen debranching enzyme; Provisional; Region: PRK03705
1104326013850	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1104326013851	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1104326013852	active site
1104326013853	catalytic site [active]
1104326013854	glycogen branching enzyme; Provisional; Region: PRK05402
1104326013855	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1104326013856	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1104326013857	active site
1104326013858	catalytic site [active]
1104326013859	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1104326013860	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1104326013861	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1104326013862	putative antibiotic transporter; Provisional; Region: PRK10739
1104326013863	low affinity gluconate transporter; Provisional; Region: PRK10472
1104326013864	gluconate transporter; Region: gntP; TIGR00791
1104326013865	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1104326013866	ATP-binding site [chemical binding]; other site
1104326013867	Gluconate-6-phosphate binding site [chemical binding]; other site
1104326013868	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1104326013869	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326013870	DNA binding site [nucleotide binding]
1104326013871	domain linker motif; other site
1104326013872	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1104326013873	putative ligand binding site [chemical binding]; other site
1104326013874	putative dimerization interface [polypeptide binding]; other site
1104326013875	Pirin-related protein [General function prediction only]; Region: COG1741
1104326013876	Pirin; Region: Pirin; pfam02678
1104326013877	potential frameshift: common BLAST hit: gi|296105133|ref|YP_003615279.1| putative dehydrogenase
1104326013878	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1104326013879	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326013880	Coenzyme A binding pocket [chemical binding]; other site
1104326013881	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1104326013882	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1104326013883	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1104326013884	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1104326013885	putative active site [active]
1104326013886	catalytic site [active]
1104326013887	putative metal binding site [ion binding]; other site
1104326013888	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1104326013889	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1104326013890	Walker A/P-loop; other site
1104326013891	ATP binding site [chemical binding]; other site
1104326013892	Q-loop/lid; other site
1104326013893	ABC transporter signature motif; other site
1104326013894	Walker B; other site
1104326013895	D-loop; other site
1104326013896	H-loop/switch region; other site
1104326013897	TOBE domain; Region: TOBE_2; pfam08402
1104326013898	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1104326013899	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326013900	dimer interface [polypeptide binding]; other site
1104326013901	conserved gate region; other site
1104326013902	putative PBP binding loops; other site
1104326013903	ABC-ATPase subunit interface; other site
1104326013904	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1104326013905	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326013906	putative PBP binding loops; other site
1104326013907	dimer interface [polypeptide binding]; other site
1104326013908	ABC-ATPase subunit interface; other site
1104326013909	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1104326013910	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1104326013911	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1104326013912	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1104326013913	Walker A/P-loop; other site
1104326013914	ATP binding site [chemical binding]; other site
1104326013915	Q-loop/lid; other site
1104326013916	ABC transporter signature motif; other site
1104326013917	Walker B; other site
1104326013918	D-loop; other site
1104326013919	H-loop/switch region; other site
1104326013920	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1104326013921	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1104326013922	Walker A/P-loop; other site
1104326013923	ATP binding site [chemical binding]; other site
1104326013924	Q-loop/lid; other site
1104326013925	ABC transporter signature motif; other site
1104326013926	Walker B; other site
1104326013927	D-loop; other site
1104326013928	H-loop/switch region; other site
1104326013929	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1104326013930	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1104326013931	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1104326013932	TM-ABC transporter signature motif; other site
1104326013933	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326013934	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1104326013935	TM-ABC transporter signature motif; other site
1104326013936	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1104326013937	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1104326013938	dimerization interface [polypeptide binding]; other site
1104326013939	ligand binding site [chemical binding]; other site
1104326013940	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1104326013941	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1104326013942	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1104326013943	dimerization interface [polypeptide binding]; other site
1104326013944	ligand binding site [chemical binding]; other site
1104326013945	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
1104326013946	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1104326013947	inhibitor-cofactor binding pocket; inhibition site
1104326013948	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326013949	catalytic residue [active]
1104326013950	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1104326013951	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1104326013952	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1104326013953	DNA binding residues [nucleotide binding]
1104326013954	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1104326013955	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1104326013956	cell division protein FtsE; Provisional; Region: PRK10908
1104326013957	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1104326013958	Walker A/P-loop; other site
1104326013959	ATP binding site [chemical binding]; other site
1104326013960	Q-loop/lid; other site
1104326013961	ABC transporter signature motif; other site
1104326013962	Walker B; other site
1104326013963	D-loop; other site
1104326013964	H-loop/switch region; other site
1104326013965	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1104326013966	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1104326013967	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1104326013968	P loop; other site
1104326013969	GTP binding site [chemical binding]; other site
1104326013970	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1104326013971	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326013972	S-adenosylmethionine binding site [chemical binding]; other site
1104326013973	hypothetical protein; Provisional; Region: PRK10910
1104326013974	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1104326013975	Predicted membrane protein [Function unknown]; Region: COG3714
1104326013976	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1104326013977	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1104326013978	metal-binding site [ion binding]
1104326013979	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1104326013980	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1104326013981	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1104326013982	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1104326013983	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1104326013984	DctM-like transporters; Region: DctM; pfam06808
1104326013985	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1104326013986	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1104326013987	CPxP  motif; other site
1104326013988	hypothetical protein; Provisional; Region: PRK11212
1104326013989	hypothetical protein; Provisional; Region: PRK11615
1104326013990	major facilitator superfamily transporter; Provisional; Region: PRK05122
1104326013991	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326013992	putative substrate translocation pore; other site
1104326013993	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1104326013994	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1104326013995	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
1104326013996	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1104326013997	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1104326013998	putative acyl-acceptor binding pocket; other site
1104326013999	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1104326014000	acyl carrier protein; Provisional; Region: PRK05350
1104326014001	Predicted membrane protein [Function unknown]; Region: COG4648
1104326014002	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
1104326014003	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1104326014004	acyl-activating enzyme (AAE) consensus motif; other site
1104326014005	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1104326014006	CoA binding site [chemical binding]; other site
1104326014007	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1104326014008	active site 2 [active]
1104326014009	active site 1 [active]
1104326014010	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1104326014011	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1104326014012	Ligand binding site; other site
1104326014013	Putative Catalytic site; other site
1104326014014	DXD motif; other site
1104326014015	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1104326014016	putative acyl-acceptor binding pocket; other site
1104326014017	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1104326014018	active site
1104326014019	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1104326014020	Predicted exporter [General function prediction only]; Region: COG4258
1104326014021	Protein of unknown function (DUF3261); Region: DUF3261; pfam11659
1104326014022	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
1104326014023	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1104326014024	dimer interface [polypeptide binding]; other site
1104326014025	active site
1104326014026	Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289
1104326014027	putative active site 1 [active]
1104326014028	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326014029	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
1104326014030	NAD(P) binding site [chemical binding]; other site
1104326014031	active site
1104326014032	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
1104326014033	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1104326014034	dimer interface [polypeptide binding]; other site
1104326014035	active site
1104326014036	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1104326014037	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1104326014038	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1104326014039	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1104326014040	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1104326014041	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1104326014042	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1104326014043	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1104326014044	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1104326014045	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1104326014046	active site
1104326014047	substrate binding site [chemical binding]; other site
1104326014048	cosubstrate binding site; other site
1104326014049	catalytic site [active]
1104326014050	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1104326014051	active site
1104326014052	hexamer interface [polypeptide binding]; other site
1104326014053	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1104326014054	NAD binding site [chemical binding]; other site
1104326014055	substrate binding site [chemical binding]; other site
1104326014056	active site
1104326014057	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1104326014058	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1104326014059	Ligand binding site; other site
1104326014060	Putative Catalytic site; other site
1104326014061	DXD motif; other site
1104326014062	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1104326014063	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1104326014064	inhibitor-cofactor binding pocket; inhibition site
1104326014065	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326014066	catalytic residue [active]
1104326014067	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; pfam05870
1104326014068	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326014069	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326014070	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1104326014071	dimerization interface [polypeptide binding]; other site
1104326014072	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1104326014073	classical (c) SDRs; Region: SDR_c; cd05233
1104326014074	NAD(P) binding site [chemical binding]; other site
1104326014075	active site
1104326014076	NlpC/P60 family; Region: NLPC_P60; pfam00877
1104326014077	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1104326014078	Integral membrane protein TerC family; Region: TerC; cl10468
1104326014079	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326014080	D-galactonate transporter; Region: 2A0114; TIGR00893
1104326014081	putative substrate translocation pore; other site
1104326014082	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1104326014083	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1104326014084	Bacterial transcriptional regulator; Region: IclR; pfam01614
1104326014085	hypothetical protein; Validated; Region: PRK06201
1104326014086	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
1104326014087	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1104326014088	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1104326014089	ligand binding site [chemical binding]; other site
1104326014090	NAD binding site [chemical binding]; other site
1104326014091	dimerization interface [polypeptide binding]; other site
1104326014092	catalytic site [active]
1104326014093	Predicted flavoproteins [General function prediction only]; Region: COG2081
1104326014094	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326014095	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1104326014096	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1104326014097	universal stress protein UspB; Provisional; Region: PRK04960
1104326014098	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1104326014099	Ligand Binding Site [chemical binding]; other site
1104326014100	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326014101	S-adenosylmethionine binding site [chemical binding]; other site
1104326014102	oligopeptidase A; Provisional; Region: PRK10911
1104326014103	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1104326014104	active site
1104326014105	Zn binding site [ion binding]; other site
1104326014106	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1104326014107	glutathione reductase; Validated; Region: PRK06116
1104326014108	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1104326014109	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326014110	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1104326014111	aminoglycoside resistance protein; Provisional; Region: PRK13746
1104326014112	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1104326014113	active site
1104326014114	NTP binding site [chemical binding]; other site
1104326014115	metal binding triad [ion binding]; metal-binding site
1104326014116	antibiotic binding site [chemical binding]; other site
1104326014117	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1104326014118	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
1104326014119	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326014120	substrate binding pocket [chemical binding]; other site
1104326014121	membrane-bound complex binding site; other site
1104326014122	hinge residues; other site
1104326014123	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326014124	substrate binding pocket [chemical binding]; other site
1104326014125	membrane-bound complex binding site; other site
1104326014126	hinge residues; other site
1104326014127	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1104326014128	putative active site [active]
1104326014129	heme pocket [chemical binding]; other site
1104326014130	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326014131	dimer interface [polypeptide binding]; other site
1104326014132	phosphorylation site [posttranslational modification]
1104326014133	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326014134	ATP binding site [chemical binding]; other site
1104326014135	Mg2+ binding site [ion binding]; other site
1104326014136	G-X-G motif; other site
1104326014137	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326014138	active site
1104326014139	phosphorylation site [posttranslational modification]
1104326014140	intermolecular recognition site; other site
1104326014141	dimerization interface [polypeptide binding]; other site
1104326014142	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1104326014143	putative binding surface; other site
1104326014144	active site
1104326014145	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1104326014146	outer membrane protease; Reviewed; Region: PRK10993
1104326014147	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326014148	TPR motif; other site
1104326014149	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1104326014150	binding surface
1104326014151	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326014152	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326014153	substrate binding pocket [chemical binding]; other site
1104326014154	membrane-bound complex binding site; other site
1104326014155	hinge residues; other site
1104326014156	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326014157	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1104326014158	substrate binding pocket [chemical binding]; other site
1104326014159	membrane-bound complex binding site; other site
1104326014160	hinge residues; other site
1104326014161	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1104326014162	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326014163	dimer interface [polypeptide binding]; other site
1104326014164	phosphorylation site [posttranslational modification]
1104326014165	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326014166	ATP binding site [chemical binding]; other site
1104326014167	Mg2+ binding site [ion binding]; other site
1104326014168	G-X-G motif; other site
1104326014169	Response regulator receiver domain; Region: Response_reg; pfam00072
1104326014170	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326014171	active site
1104326014172	phosphorylation site [posttranslational modification]
1104326014173	intermolecular recognition site; other site
1104326014174	dimerization interface [polypeptide binding]; other site
1104326014175	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326014176	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326014177	active site
1104326014178	phosphorylation site [posttranslational modification]
1104326014179	intermolecular recognition site; other site
1104326014180	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326014181	DNA binding residues [nucleotide binding]
1104326014182	dimerization interface [polypeptide binding]; other site
1104326014183	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1104326014184	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1104326014185	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1104326014186	HlyD family secretion protein; Region: HlyD_3; pfam13437
1104326014187	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1104326014188	putative active site [active]
1104326014189	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1104326014190	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1104326014191	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
1104326014192	Walker A/P-loop; other site
1104326014193	ATP binding site [chemical binding]; other site
1104326014194	Q-loop/lid; other site
1104326014195	ABC transporter signature motif; other site
1104326014196	Walker B; other site
1104326014197	D-loop; other site
1104326014198	H-loop/switch region; other site
1104326014199	Protein of unknown function (DUF2846); Region: DUF2846; pfam11008
1104326014200	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1104326014201	ligand binding site [chemical binding]; other site
1104326014202	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014203	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014204	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014205	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014206	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014207	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014208	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014209	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
1104326014210	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1104326014211	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326014212	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326014213	active site
1104326014214	phosphorylation site [posttranslational modification]
1104326014215	intermolecular recognition site; other site
1104326014216	dimerization interface [polypeptide binding]; other site
1104326014217	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326014218	dimerization interface [polypeptide binding]; other site
1104326014219	DNA binding residues [nucleotide binding]
1104326014220	trehalase; Provisional; Region: treF; PRK13270
1104326014221	Trehalase; Region: Trehalase; pfam01204
1104326014222	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1104326014223	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1104326014224	Coenzyme A binding pocket [chemical binding]; other site
1104326014225	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1104326014226	catalytic residue [active]
1104326014227	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1104326014228	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1104326014229	DNA binding residues [nucleotide binding]
1104326014230	dimerization interface [polypeptide binding]; other site
1104326014231	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1104326014232	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1104326014233	NAD(P) binding site [chemical binding]; other site
1104326014234	active site
1104326014235	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1104326014236	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326014237	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1104326014238	putative effector binding pocket; other site
1104326014239	putative dimerization interface [polypeptide binding]; other site
1104326014240	inner membrane protein YhjD; Region: TIGR00766
1104326014241	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326014242	metabolite-proton symporter; Region: 2A0106; TIGR00883
1104326014243	putative substrate translocation pore; other site
1104326014244	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1104326014245	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1104326014246	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326014247	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326014248	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1104326014249	substrate binding site [chemical binding]; other site
1104326014250	ATP binding site [chemical binding]; other site
1104326014251	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1104326014252	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1104326014253	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1104326014254	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1104326014255	putative diguanylate cyclase; Provisional; Region: PRK13561
1104326014256	HAMP domain; Region: HAMP; pfam00672
1104326014257	dimerization interface [polypeptide binding]; other site
1104326014258	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1104326014259	metal binding site [ion binding]; metal-binding site
1104326014260	active site
1104326014261	I-site; other site
1104326014262	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1104326014263	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1104326014264	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326014265	binding surface
1104326014266	TPR motif; other site
1104326014267	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1104326014268	binding surface
1104326014269	TPR motif; other site
1104326014270	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1104326014271	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1104326014272	cellulose synthase regulator protein; Provisional; Region: PRK11114
1104326014273	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1104326014274	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1104326014275	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1104326014276	DXD motif; other site
1104326014277	PilZ domain; Region: PilZ; pfam07238
1104326014278	cell division protein; Provisional; Region: PRK10037
1104326014279	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1104326014280	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1104326014281	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1104326014282	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1104326014283	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
1104326014284	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
1104326014285	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1104326014286	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1104326014287	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1104326014288	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1104326014289	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1104326014290	FAD binding domain; Region: FAD_binding_4; pfam01565
1104326014291	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1104326014292	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1104326014293	potassium transporter; Provisional; Region: PRK10750
1104326014294	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1104326014295	hypothetical protein; Provisional; Region: PRK11568
1104326014296	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1104326014297	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1104326014298	proline dipeptidase; Provisional; Region: PRK13607
1104326014299	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1104326014300	active site
1104326014301	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1104326014302	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1104326014303	substrate binding site [chemical binding]; other site
1104326014304	oxyanion hole (OAH) forming residues; other site
1104326014305	trimer interface [polypeptide binding]; other site
1104326014306	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1104326014307	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1104326014308	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1104326014309	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1104326014310	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1104326014311	dimer interface [polypeptide binding]; other site
1104326014312	active site
1104326014313	FMN reductase; Validated; Region: fre; PRK08051
1104326014314	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1104326014315	FAD binding pocket [chemical binding]; other site
1104326014316	FAD binding motif [chemical binding]; other site
1104326014317	phosphate binding motif [ion binding]; other site
1104326014318	beta-alpha-beta structure motif; other site
1104326014319	NAD binding pocket [chemical binding]; other site
1104326014320	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1104326014321	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1104326014322	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1104326014323	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1104326014324	active site
1104326014325	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1104326014326	sec-independent translocase; Provisional; Region: PRK01770
1104326014327	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1104326014328	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1104326014329	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1104326014330	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1104326014331	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1104326014332	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1104326014333	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326014334	S-adenosylmethionine binding site [chemical binding]; other site
1104326014335	DNA recombination protein RmuC; Provisional; Region: PRK10361
1104326014336	RmuC family; Region: RmuC; pfam02646
1104326014337	uridine phosphorylase; Provisional; Region: PRK11178
1104326014338	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1104326014339	potential frameshift: common BLAST hit: gi|365972638|ref|YP_004954199.1| putative carboxymethylenebutenolidase
1104326014340	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1104326014341	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1104326014342	THF binding site; other site
1104326014343	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1104326014344	substrate binding site [chemical binding]; other site
1104326014345	THF binding site; other site
1104326014346	zinc-binding site [ion binding]; other site
1104326014347	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1104326014348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326014349	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1104326014350	putative dimerization interface [polypeptide binding]; other site
1104326014351	EamA-like transporter family; Region: EamA; pfam00892
1104326014352	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1104326014353	EamA-like transporter family; Region: EamA; pfam00892
1104326014354	putative hydrolase; Provisional; Region: PRK10976
1104326014355	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326014356	active site
1104326014357	motif I; other site
1104326014358	motif II; other site
1104326014359	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326014360	lysophospholipase L2; Provisional; Region: PRK10749
1104326014361	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1104326014362	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1104326014363	threonine efflux system; Provisional; Region: PRK10229
1104326014364	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1104326014365	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326014366	ATP binding site [chemical binding]; other site
1104326014367	putative Mg++ binding site [ion binding]; other site
1104326014368	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326014369	nucleotide binding region [chemical binding]; other site
1104326014370	ATP-binding site [chemical binding]; other site
1104326014371	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1104326014372	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1104326014373	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1104326014374	dimerization interface [polypeptide binding]; other site
1104326014375	substrate binding site [chemical binding]; other site
1104326014376	active site
1104326014377	calcium binding site [ion binding]; other site
1104326014378	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1104326014379	CoenzymeA binding site [chemical binding]; other site
1104326014380	subunit interaction site [polypeptide binding]; other site
1104326014381	PHB binding site; other site
1104326014382	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1104326014383	EamA-like transporter family; Region: EamA; pfam00892
1104326014384	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1104326014385	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1104326014386	Cl binding site [ion binding]; other site
1104326014387	oligomer interface [polypeptide binding]; other site
1104326014388	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1104326014389	Part of AAA domain; Region: AAA_19; pfam13245
1104326014390	Family description; Region: UvrD_C_2; pfam13538
1104326014391	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1104326014392	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326014393	motif II; other site
1104326014394	potential frameshift: common BLAST hit: gi|296105305|ref|YP_003615451.1| site-specific tyrosine recombinase XerC
1104326014395	hypothetical protein; Provisional; Region: PRK10963
1104326014396	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1104326014397	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1104326014398	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1104326014399	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1104326014400	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1104326014401	putative iron binding site [ion binding]; other site
1104326014402	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1104326014403	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1104326014404	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1104326014405	potential frameshift: common BLAST hit: gi|296105312|ref|YP_003615458.1| hydroxymethylbilane synthase
1104326014406	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1104326014407	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1104326014408	active site
1104326014409	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1104326014410	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1104326014411	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1104326014412	HemY protein N-terminus; Region: HemY_N; pfam07219
1104326014413	potential protein location (hypothetical protein A3UG_22165 [Enterobacter cloacae subsp. dissolvens SDM]) that overlaps RNA (tRNA-P)
1104326014414	putative transport protein YifK; Provisional; Region: PRK10746
1104326014415	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1104326014416	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1104326014417	putative common antigen polymerase; Provisional; Region: PRK02975
1104326014418	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1104326014419	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1104326014420	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1104326014421	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1104326014422	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1104326014423	inhibitor-cofactor binding pocket; inhibition site
1104326014424	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326014425	catalytic residue [active]
1104326014426	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326014427	Coenzyme A binding pocket [chemical binding]; other site
1104326014428	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1104326014429	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1104326014430	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1104326014431	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1104326014432	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1104326014433	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1104326014434	active site
1104326014435	homodimer interface [polypeptide binding]; other site
1104326014436	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1104326014437	Chain length determinant protein; Region: Wzz; pfam02706
1104326014438	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1104326014439	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1104326014440	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1104326014441	Mg++ binding site [ion binding]; other site
1104326014442	putative catalytic motif [active]
1104326014443	substrate binding site [chemical binding]; other site
1104326014444	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1104326014445	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1104326014446	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1104326014447	RNA binding site [nucleotide binding]; other site
1104326014448	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1104326014449	multimer interface [polypeptide binding]; other site
1104326014450	Walker A motif; other site
1104326014451	ATP binding site [chemical binding]; other site
1104326014452	Walker B motif; other site
1104326014453	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1104326014454	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1104326014455	catalytic residues [active]
1104326014456	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1104326014457	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1104326014458	ATP binding site [chemical binding]; other site
1104326014459	Mg++ binding site [ion binding]; other site
1104326014460	motif III; other site
1104326014461	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1104326014462	nucleotide binding region [chemical binding]; other site
1104326014463	ATP-binding site [chemical binding]; other site
1104326014464	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1104326014465	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1104326014466	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1104326014467	Part of AAA domain; Region: AAA_19; pfam13245
1104326014468	Family description; Region: UvrD_C_2; pfam13538
1104326014469	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1104326014470	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1104326014471	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1104326014472	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1104326014473	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1104326014474	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326014475	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1104326014476	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1104326014477	putative dimerization interface [polypeptide binding]; other site
1104326014478	threonine dehydratase; Reviewed; Region: PRK09224
1104326014479	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1104326014480	tetramer interface [polypeptide binding]; other site
1104326014481	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326014482	catalytic residue [active]
1104326014483	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1104326014484	putative Ile/Val binding site [chemical binding]; other site
1104326014485	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1104326014486	putative Ile/Val binding site [chemical binding]; other site
1104326014487	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1104326014488	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1104326014489	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1104326014490	homodimer interface [polypeptide binding]; other site
1104326014491	substrate-cofactor binding pocket; other site
1104326014492	catalytic residue [active]
1104326014493	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1104326014494	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1104326014495	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1104326014496	PYR/PP interface [polypeptide binding]; other site
1104326014497	dimer interface [polypeptide binding]; other site
1104326014498	TPP binding site [chemical binding]; other site
1104326014499	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1104326014500	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1104326014501	TPP-binding site [chemical binding]; other site
1104326014502	dimer interface [polypeptide binding]; other site
1104326014503	putative ATP-dependent protease; Provisional; Region: PRK09862
1104326014504	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1104326014505	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326014506	Walker A motif; other site
1104326014507	ATP binding site [chemical binding]; other site
1104326014508	Walker B motif; other site
1104326014509	arginine finger; other site
1104326014510	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1104326014511	hypothetical protein; Provisional; Region: PRK11027
1104326014512	transcriptional regulator HdfR; Provisional; Region: PRK03601
1104326014513	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326014514	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1104326014515	dimerization interface [polypeptide binding]; other site
1104326014516	glutamate racemase; Provisional; Region: PRK00865
1104326014517	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1104326014518	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1104326014519	N-terminal plug; other site
1104326014520	ligand-binding site [chemical binding]; other site
1104326014521	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1104326014522	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326014523	S-adenosylmethionine binding site [chemical binding]; other site
1104326014524	hypothetical protein; Provisional; Region: PRK11056
1104326014525	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1104326014526	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1104326014527	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1104326014528	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1104326014529	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1104326014530	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1104326014531	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326014532	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1104326014533	dimerization interface [polypeptide binding]; other site
1104326014534	argininosuccinate lyase; Provisional; Region: PRK04833
1104326014535	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1104326014536	active sites [active]
1104326014537	tetramer interface [polypeptide binding]; other site
1104326014538	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1104326014539	nucleotide binding site [chemical binding]; other site
1104326014540	N-acetyl-L-glutamate binding site [chemical binding]; other site
1104326014541	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1104326014542	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1104326014543	acetylornithine deacetylase; Provisional; Region: PRK05111
1104326014544	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1104326014545	metal binding site [ion binding]; metal-binding site
1104326014546	putative dimer interface [polypeptide binding]; other site
1104326014547	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1104326014548	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1104326014549	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1104326014550	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326014551	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1104326014552	active site
1104326014553	intersubunit interactions; other site
1104326014554	catalytic residue [active]
1104326014555	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1104326014556	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1104326014557	dimer interface [polypeptide binding]; other site
1104326014558	active site
1104326014559	metal binding site [ion binding]; metal-binding site
1104326014560	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1104326014561	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1104326014562	heme binding site [chemical binding]; other site
1104326014563	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1104326014564	heme binding site [chemical binding]; other site
1104326014565	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1104326014566	FAD binding site [chemical binding]; other site
1104326014567	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1104326014568	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1104326014569	putative catalytic residues [active]
1104326014570	putative nucleotide binding site [chemical binding]; other site
1104326014571	putative aspartate binding site [chemical binding]; other site
1104326014572	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1104326014573	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1104326014574	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1104326014575	cystathionine gamma-synthase; Provisional; Region: PRK08045
1104326014576	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1104326014577	homodimer interface [polypeptide binding]; other site
1104326014578	substrate-cofactor binding pocket; other site
1104326014579	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1104326014580	catalytic residue [active]
1104326014581	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1104326014582	dimerization interface [polypeptide binding]; other site
1104326014583	DNA binding site [nucleotide binding]
1104326014584	corepressor binding sites; other site
1104326014585	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1104326014586	primosome assembly protein PriA; Validated; Region: PRK05580
1104326014587	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1104326014588	ATP binding site [chemical binding]; other site
1104326014589	putative Mg++ binding site [ion binding]; other site
1104326014590	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1104326014591	ATP-binding site [chemical binding]; other site
1104326014592	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326014593	DNA binding site [nucleotide binding]
1104326014594	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1104326014595	domain linker motif; other site
1104326014596	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1104326014597	dimerization interface [polypeptide binding]; other site
1104326014598	ligand binding site [chemical binding]; other site
1104326014599	essential cell division protein FtsN; Provisional; Region: PRK10927
1104326014600	cell division protein FtsN; Provisional; Region: PRK12757
1104326014601	Sporulation related domain; Region: SPOR; cl10051
1104326014602	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1104326014603	active site
1104326014604	HslU subunit interaction site [polypeptide binding]; other site
1104326014605	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1104326014606	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326014607	Walker A motif; other site
1104326014608	ATP binding site [chemical binding]; other site
1104326014609	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1104326014610	Walker B motif; other site
1104326014611	arginine finger; other site
1104326014612	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1104326014613	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1104326014614	UbiA prenyltransferase family; Region: UbiA; pfam01040
1104326014615	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1104326014616	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1104326014617	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1104326014618	amphipathic channel; other site
1104326014619	Asn-Pro-Ala signature motifs; other site
1104326014620	glycerol kinase; Provisional; Region: glpK; PRK00047
1104326014621	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1104326014622	N- and C-terminal domain interface [polypeptide binding]; other site
1104326014623	active site
1104326014624	MgATP binding site [chemical binding]; other site
1104326014625	catalytic site [active]
1104326014626	metal binding site [ion binding]; metal-binding site
1104326014627	glycerol binding site [chemical binding]; other site
1104326014628	homotetramer interface [polypeptide binding]; other site
1104326014629	homodimer interface [polypeptide binding]; other site
1104326014630	FBP binding site [chemical binding]; other site
1104326014631	protein IIAGlc interface [polypeptide binding]; other site
1104326014632	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1104326014633	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1104326014634	putative active site [active]
1104326014635	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1104326014636	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1104326014637	FAD binding pocket [chemical binding]; other site
1104326014638	FAD binding motif [chemical binding]; other site
1104326014639	phosphate binding motif [ion binding]; other site
1104326014640	beta-alpha-beta structure motif; other site
1104326014641	NAD binding pocket [chemical binding]; other site
1104326014642	Predicted membrane protein [Function unknown]; Region: COG3152
1104326014643	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1104326014644	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1104326014645	triosephosphate isomerase; Provisional; Region: PRK14567
1104326014646	substrate binding site [chemical binding]; other site
1104326014647	dimer interface [polypeptide binding]; other site
1104326014648	catalytic triad [active]
1104326014649	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1104326014650	transmembrane helices; other site
1104326014651	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1104326014652	CDP-diacylglycerol pyrophosphatase; Provisional; Region: PRK05471
1104326014653	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326014654	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1104326014655	substrate binding pocket [chemical binding]; other site
1104326014656	membrane-bound complex binding site; other site
1104326014657	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1104326014658	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1104326014659	active site
1104326014660	ADP/pyrophosphate binding site [chemical binding]; other site
1104326014661	dimerization interface [polypeptide binding]; other site
1104326014662	allosteric effector site; other site
1104326014663	fructose-1,6-bisphosphate binding site; other site
1104326014664	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1104326014665	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1104326014666	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1104326014667	dimer interface [polypeptide binding]; other site
1104326014668	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1104326014669	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326014670	active site
1104326014671	intermolecular recognition site; other site
1104326014672	dimerization interface [polypeptide binding]; other site
1104326014673	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1104326014674	DNA binding site [nucleotide binding]
1104326014675	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1104326014676	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1104326014677	dimerization interface [polypeptide binding]; other site
1104326014678	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326014679	dimer interface [polypeptide binding]; other site
1104326014680	phosphorylation site [posttranslational modification]
1104326014681	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326014682	ATP binding site [chemical binding]; other site
1104326014683	Mg2+ binding site [ion binding]; other site
1104326014684	G-X-G motif; other site
1104326014685	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1104326014686	MOSC domain; Region: MOSC; pfam03473
1104326014687	3-alpha domain; Region: 3-alpha; pfam03475
1104326014688	superoxide dismutase; Provisional; Region: PRK10925
1104326014689	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1104326014690	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1104326014691	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1104326014692	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1104326014693	transcriptional activator RhaR; Provisional; Region: PRK13502
1104326014694	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326014695	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326014696	transcriptional activator RhaS; Provisional; Region: PRK13503
1104326014697	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1104326014698	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326014699	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1104326014700	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1104326014701	N- and C-terminal domain interface [polypeptide binding]; other site
1104326014702	active site
1104326014703	putative catalytic site [active]
1104326014704	metal binding site [ion binding]; metal-binding site
1104326014705	ATP binding site [chemical binding]; other site
1104326014706	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1104326014707	carbohydrate binding site [chemical binding]; other site
1104326014708	L-rhamnose isomerase; Provisional; Region: PRK01076
1104326014709	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1104326014710	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1104326014711	intersubunit interface [polypeptide binding]; other site
1104326014712	active site
1104326014713	Zn2+ binding site [ion binding]; other site
1104326014714	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1104326014715	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1104326014716	dimer interface [polypeptide binding]; other site
1104326014717	active site
1104326014718	metal binding site [ion binding]; metal-binding site
1104326014719	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1104326014720	galactoside permease; Reviewed; Region: lacY; PRK09528
1104326014721	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326014722	putative substrate translocation pore; other site
1104326014723	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1104326014724	Melibiase; Region: Melibiase; pfam02065
1104326014725	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1104326014726	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326014727	DNA binding site [nucleotide binding]
1104326014728	domain linker motif; other site
1104326014729	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
1104326014730	ligand binding site [chemical binding]; other site
1104326014731	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1104326014732	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1104326014733	non-specific DNA binding site [nucleotide binding]; other site
1104326014734	salt bridge; other site
1104326014735	sequence-specific DNA binding site [nucleotide binding]; other site
1104326014736	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1104326014737	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1104326014738	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1104326014739	hypothetical protein; Provisional; Region: PRK15301
1104326014740	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
1104326014741	PapC N-terminal domain; Region: PapC_N; pfam13954
1104326014742	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1104326014743	PapC C-terminal domain; Region: PapC_C; pfam13953
1104326014744	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1104326014745	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1104326014746	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1104326014747	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1104326014748	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326014749	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1104326014750	molybdopterin cofactor binding site; other site
1104326014751	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1104326014752	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1104326014753	molybdopterin cofactor binding site; other site
1104326014754	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1104326014755	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1104326014756	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1104326014757	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1104326014758	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1104326014759	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1104326014760	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1104326014761	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1104326014762	substrate binding pocket [chemical binding]; other site
1104326014763	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1104326014764	Coenzyme A binding pocket [chemical binding]; other site
1104326014765	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1104326014766	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1104326014767	putative active site [active]
1104326014768	dimerization interface [polypeptide binding]; other site
1104326014769	putative tRNAtyr binding site [nucleotide binding]; other site
1104326014770	hypothetical protein; Reviewed; Region: PRK01637
1104326014771	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1104326014772	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326014773	motif II; other site
1104326014774	GTP-binding protein; Provisional; Region: PRK10218
1104326014775	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1104326014776	G1 box; other site
1104326014777	putative GEF interaction site [polypeptide binding]; other site
1104326014778	GTP/Mg2+ binding site [chemical binding]; other site
1104326014779	Switch I region; other site
1104326014780	G2 box; other site
1104326014781	G3 box; other site
1104326014782	Switch II region; other site
1104326014783	G4 box; other site
1104326014784	G5 box; other site
1104326014785	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1104326014786	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1104326014787	glutamine synthetase; Provisional; Region: glnA; PRK09469
1104326014788	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1104326014789	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1104326014790	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1104326014791	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1104326014792	putative active site [active]
1104326014793	heme pocket [chemical binding]; other site
1104326014794	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1104326014795	dimer interface [polypeptide binding]; other site
1104326014796	phosphorylation site [posttranslational modification]
1104326014797	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1104326014798	ATP binding site [chemical binding]; other site
1104326014799	Mg2+ binding site [ion binding]; other site
1104326014800	G-X-G motif; other site
1104326014801	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1104326014802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1104326014803	active site
1104326014804	phosphorylation site [posttranslational modification]
1104326014805	intermolecular recognition site; other site
1104326014806	dimerization interface [polypeptide binding]; other site
1104326014807	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326014808	Walker A motif; other site
1104326014809	ATP binding site [chemical binding]; other site
1104326014810	Walker B motif; other site
1104326014811	arginine finger; other site
1104326014812	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1104326014813	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1104326014814	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1104326014815	FeS/SAM binding site; other site
1104326014816	HemN C-terminal domain; Region: HemN_C; pfam06969
1104326014817	Der GTPase activator; Provisional; Region: PRK05244
1104326014818	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1104326014819	G1 box; other site
1104326014820	GTP/Mg2+ binding site [chemical binding]; other site
1104326014821	Switch I region; other site
1104326014822	G2 box; other site
1104326014823	G3 box; other site
1104326014824	Switch II region; other site
1104326014825	G4 box; other site
1104326014826	G5 box; other site
1104326014827	DNA polymerase I; Provisional; Region: PRK05755
1104326014828	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1104326014829	active site
1104326014830	metal binding site 1 [ion binding]; metal-binding site
1104326014831	putative 5' ssDNA interaction site; other site
1104326014832	metal binding site 3; metal-binding site
1104326014833	metal binding site 2 [ion binding]; metal-binding site
1104326014834	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1104326014835	putative DNA binding site [nucleotide binding]; other site
1104326014836	putative metal binding site [ion binding]; other site
1104326014837	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1104326014838	active site
1104326014839	catalytic site [active]
1104326014840	substrate binding site [chemical binding]; other site
1104326014841	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1104326014842	active site
1104326014843	DNA binding site [nucleotide binding]
1104326014844	catalytic site [active]
1104326014845	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1104326014846	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1104326014847	putative acyl-acceptor binding pocket; other site
1104326014848	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1104326014849	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1104326014850	catalytic residues [active]
1104326014851	hinge region; other site
1104326014852	alpha helical domain; other site
1104326014853	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1104326014854	serine/threonine protein kinase; Provisional; Region: PRK11768
1104326014855	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1104326014856	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1104326014857	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1104326014858	GTP binding site; other site
1104326014859	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1104326014860	Walker A motif; other site
1104326014861	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1104326014862	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1104326014863	DNA-binding site [nucleotide binding]; DNA binding site
1104326014864	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1104326014865	putative transporter; Provisional; Region: PRK10504
1104326014866	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326014867	putative substrate translocation pore; other site
1104326014868	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326014869	transcriptional repressor RbsR; Provisional; Region: PRK10423
1104326014870	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1104326014871	DNA binding site [nucleotide binding]
1104326014872	domain linker motif; other site
1104326014873	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1104326014874	dimerization interface [polypeptide binding]; other site
1104326014875	ligand binding site [chemical binding]; other site
1104326014876	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1104326014877	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1104326014878	substrate binding site [chemical binding]; other site
1104326014879	dimer interface [polypeptide binding]; other site
1104326014880	ATP binding site [chemical binding]; other site
1104326014881	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1104326014882	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1104326014883	ligand binding site [chemical binding]; other site
1104326014884	dimerization interface [polypeptide binding]; other site
1104326014885	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1104326014886	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1104326014887	TM-ABC transporter signature motif; other site
1104326014888	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1104326014889	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1104326014890	Walker A/P-loop; other site
1104326014891	ATP binding site [chemical binding]; other site
1104326014892	Q-loop/lid; other site
1104326014893	ABC transporter signature motif; other site
1104326014894	Walker B; other site
1104326014895	D-loop; other site
1104326014896	H-loop/switch region; other site
1104326014897	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1104326014898	D-ribose pyranase; Provisional; Region: PRK11797
1104326014899	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1104326014900	potassium uptake protein; Region: kup; TIGR00794
1104326014901	regulatory ATPase RavA; Provisional; Region: PRK13531
1104326014902	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1104326014903	Walker A motif; other site
1104326014904	ATP binding site [chemical binding]; other site
1104326014905	Walker B motif; other site
1104326014906	arginine finger; other site
1104326014907	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1104326014908	hypothetical protein; Provisional; Region: yieM; PRK10997
1104326014909	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1104326014910	metal ion-dependent adhesion site (MIDAS); other site
1104326014911	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1104326014912	dimer interface [polypeptide binding]; other site
1104326014913	active site
1104326014914	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1104326014915	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1104326014916	putative DNA binding site [nucleotide binding]; other site
1104326014917	putative Zn2+ binding site [ion binding]; other site
1104326014918	AsnC family; Region: AsnC_trans_reg; pfam01037
1104326014919	FMN-binding protein MioC; Provisional; Region: PRK09004
1104326014920	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1104326014921	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1104326014922	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1104326014923	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1104326014924	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1104326014925	S-adenosylmethionine binding site [chemical binding]; other site
1104326014926	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1104326014927	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1104326014928	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1104326014929	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1104326014930	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1104326014931	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1104326014932	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1104326014933	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1104326014934	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1104326014935	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1104326014936	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1104326014937	beta subunit interaction interface [polypeptide binding]; other site
1104326014938	Walker A motif; other site
1104326014939	ATP binding site [chemical binding]; other site
1104326014940	Walker B motif; other site
1104326014941	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1104326014942	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1104326014943	core domain interface [polypeptide binding]; other site
1104326014944	delta subunit interface [polypeptide binding]; other site
1104326014945	epsilon subunit interface [polypeptide binding]; other site
1104326014946	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1104326014947	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1104326014948	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1104326014949	alpha subunit interaction interface [polypeptide binding]; other site
1104326014950	Walker A motif; other site
1104326014951	ATP binding site [chemical binding]; other site
1104326014952	Walker B motif; other site
1104326014953	inhibitor binding site; inhibition site
1104326014954	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1104326014955	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1104326014956	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1104326014957	gamma subunit interface [polypeptide binding]; other site
1104326014958	epsilon subunit interface [polypeptide binding]; other site
1104326014959	LBP interface [polypeptide binding]; other site
1104326014960	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1104326014961	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1104326014962	Substrate binding site; other site
1104326014963	Mg++ binding site; other site
1104326014964	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1104326014965	active site
1104326014966	substrate binding site [chemical binding]; other site
1104326014967	CoA binding site [chemical binding]; other site
1104326014968	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1104326014969	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1104326014970	glutaminase active site [active]
1104326014971	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1104326014972	dimer interface [polypeptide binding]; other site
1104326014973	active site
1104326014974	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1104326014975	dimer interface [polypeptide binding]; other site
1104326014976	active site
1104326014977	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1104326014978	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1104326014979	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326014980	dimer interface [polypeptide binding]; other site
1104326014981	conserved gate region; other site
1104326014982	putative PBP binding loops; other site
1104326014983	ABC-ATPase subunit interface; other site
1104326014984	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1104326014985	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1104326014986	dimer interface [polypeptide binding]; other site
1104326014987	conserved gate region; other site
1104326014988	putative PBP binding loops; other site
1104326014989	ABC-ATPase subunit interface; other site
1104326014990	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1104326014991	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1104326014992	Walker A/P-loop; other site
1104326014993	ATP binding site [chemical binding]; other site
1104326014994	Q-loop/lid; other site
1104326014995	ABC transporter signature motif; other site
1104326014996	Walker B; other site
1104326014997	D-loop; other site
1104326014998	H-loop/switch region; other site
1104326014999	transcriptional regulator PhoU; Provisional; Region: PRK11115
1104326015000	PhoU domain; Region: PhoU; pfam01895
1104326015001	PhoU domain; Region: PhoU; pfam01895
1104326015002	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1104326015003	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1104326015004	motif II; other site
1104326015005	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1104326015006	Predicted flavoprotein [General function prediction only]; Region: COG0431
1104326015007	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1104326015008	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1104326015009	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1104326015010	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1104326015011	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1104326015012	substrate binding pocket [chemical binding]; other site
1104326015013	dimerization interface [polypeptide binding]; other site
1104326015014	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1104326015015	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1104326015016	putative substrate translocation pore; other site
1104326015017	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1104326015018	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1104326015019	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1104326015020	G1 box; other site
1104326015021	GTP/Mg2+ binding site [chemical binding]; other site
1104326015022	Switch I region; other site
1104326015023	G2 box; other site
1104326015024	Switch II region; other site
1104326015025	G3 box; other site
1104326015026	G4 box; other site
1104326015027	G5 box; other site
1104326015028	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1104326015029	membrane protein insertase; Provisional; Region: PRK01318
1104326015030	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1104326015031	hypothetical protein; Validated; Region: PRK00041
1104326015032	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1104326015033	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399