-- dump date 20140619_075520 -- class Genbank::CDS -- table cds_note -- id note YP_002647039.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002647040.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002647041.1 silverDB:cEP00003 YP_002647042.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002647043.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_002647044.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002647045.1 silverDB:cEP00007 YP_002647046.1 silverDB:cEP00008 YP_002647047.1 silverDB:cEP00009 YP_002647048.1 silverDB:cEP00010 YP_002647049.1 silverDB:cEP00011 YP_002647050.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_002647051.1 silverDB:cEP00013 YP_002647052.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_002647053.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002647054.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_002647055.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002647056.1 DNA-binding transcriptional repressor of ribose metabolism YP_002647057.1 silverDB:cEP00019 YP_002647058.1 silverDB:cEP00020 YP_002647059.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_002647060.1 silverDB:cEP00023 YP_002647061.1 silverDB:cEP00024 YP_002647062.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002647063.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002647064.1 silverDB:cEP00027 YP_002647065.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002647066.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_002647067.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_002647068.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002647069.1 silverDB:cEP00032 YP_002647070.1 silverDB:cEP00033 YP_002647071.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_002647072.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002647073.1 silverDB:cEP00036 YP_002647074.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_002647075.1 silverDB:cEP00038 YP_002647076.1 silverDB:cEP00039 YP_002647077.1 catalyzes branch migration in Holliday junction intermediates YP_002647078.1 specifically modifies tRNA at position G18 YP_002647079.1 silverDB:cEP00042 YP_002647080.1 silverDB:cEP00043 YP_002647081.1 Essential for recycling GMP and indirectly, cGMP YP_002647082.1 this ligase is LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_002647083.1 silverDB:cEP00046 YP_002647084.1 silverDB:cEP00047 YP_002647085.1 silverDB:cEP00048 YP_002647086.1 silverDB:cEP00049 YP_002647087.1 silverDB:cEP00050 YP_002647088.1 silverDB:cEP00051 YP_002647089.1 silverDB:cEP00052 YP_002647090.1 silverDB:cEP00053 YP_002647091.1 silverDB:cEP00054 YP_002647092.1 silverDB:cEP00055 YP_002647093.1 silverDB:cEP00056 YP_002647094.1 silverDB:cEP00057 YP_002647095.1 silverDB:cEP00058 YP_002647096.1 silverDB:cEP00059 YP_002647097.1 silverDB:cEP00060 YP_002647098.1 silverDB:cEP00061 YP_002647099.1 silverDB:cEP00062 YP_002647100.1 silverDB:cEP00063 YP_002647101.1 silverDB:cEP00064 YP_002647102.1 silverDB:cEP00065 YP_002647103.1 silverDB:cEP00066 YP_002647104.1 silverDB:cEP00067 YP_002647105.1 silverDB:cEP00068 YP_002647106.1 silverDB:cEP00069 YP_002647107.1 silverDB:cEP00070 YP_002647108.1 silverDB:cEP00071 YP_002647109.1 silverDB:cEP00072 YP_002647110.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002647111.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002647112.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002647113.1 silverDB:cEP00076 YP_002647114.1 silverDB:cEP00077 YP_002647115.1 silverDB:cEP00078 YP_002647116.1 required for 70S ribosome assembly YP_002647117.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002647118.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002647119.1 silverDB:cEP00082 YP_002647120.1 silverDB:cEP00083 YP_002647121.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002647122.1 silverDB:cEP00085 YP_002647123.1 silverDB:cEP00086 YP_002647124.1 silverDB:cEP00087 YP_002647125.1 silverDB:cEP00088 YP_002647126.1 silverDB:cEP00089 YP_002647127.1 silverDB:cEP00090 YP_002647128.1 silverDB:cEP00091 YP_002647129.1 silverDB:cEP00092 YP_002647130.1 silverDB:cEP00093 YP_002647131.1 silverDB:cEP00094 YP_002647132.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_002647133.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002647134.1 silverDB:cEP00097 YP_002647135.1 silverDB:cEP00098 YP_002647136.1 silverDB:cEP00099 YP_002647137.1 silverDB:cEP00100 YP_002647138.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002647139.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002647140.1 catalyzes the O-acetylation of serine YP_002647141.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_002647142.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002647143.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_002647144.1 silverDB:cEP00107 YP_002647145.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_002647146.1 silverDB:cEP00109 YP_002647147.1 silverDB:cEP00110 YP_002647148.1 silverDB:cEP00111 YP_002647149.1 silverDB:cEP00112 YP_002647150.1 silverDB:cEP00113 YP_002647151.1 silverDB:cEP00114 YP_002647152.1 silverDB:cEP00115 YP_002647153.1 silverDB:cEP00116 YP_002647154.1 silverDB:cEP00117 YP_002647155.1 silverDB:cEP00118 YP_002647156.1 silverDB:cEP00119 YP_002647157.1 silverDB:cEP00120 YP_002647158.1 silverDB:cEP00121 YP_002647159.1 silverDB:cEP00122 YP_002647160.1 silverDB:cEP00123 YP_002647161.1 silverDB:cEP00124 YP_002647162.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002647163.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002647164.1 silverDB:cEP00127 YP_002647165.1 silverDB:cEP00128 YP_002647166.1 silverDB:cEP00129 YP_002647167.1 silverDB:cEP00130 YP_002647168.1 multidrug efflux protein involved in adaptation to low energy shock YP_002647169.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002647170.1 silverDB:cEP00133 YP_002647171.1 silverDB:cEP00134 YP_002647172.1 silverDB:cEP00135 YP_002647173.1 silverDB:cEP00136 YP_002647174.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002647175.1 heat shock protein involved in degradation of misfolded proteins YP_002647176.1 heat shock protein involved in degradation of misfolded proteins YP_002647177.1 silverDB:cEP00140 YP_002647178.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_002647179.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002647180.1 silverDB:cEP00143 YP_002647181.1 silverDB:cEP00144 YP_002647182.1 silverDB:cEP00145 YP_002647183.1 silverDB:cEP00146 YP_002647184.1 silverDB:cEP00147 YP_002647185.1 silverDB:cEP00148 YP_002647186.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002647187.1 silverDB:cEP00150 YP_002647188.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002647189.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_002647190.1 silverDB:cEP00153 YP_002647191.1 silverDB:cEP00154 YP_002647192.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002647193.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002647194.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002647195.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_002647196.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002647197.1 silverDB:cEP00160 YP_002647198.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_002647199.1 catalyzes the conversion of NADPH to NADH YP_002647200.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_002647201.1 silverDB:cEP00164 YP_002647202.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002647203.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002647204.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_002647205.1 silverDB:cEP00168 YP_002647206.1 silverDB:cEP00169 YP_002647207.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002647208.1 silverDB:cEP00171 YP_002647209.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002647210.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002647211.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_002647212.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002647213.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002647214.1 silverDB:cEP00177 YP_002647215.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_002647216.1 silverDB:cEP00179 YP_002647217.1 silverDB:cEP00180 YP_002647218.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_002647219.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_002647220.1 silverDB:cEP00183 YP_002647221.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002647222.1 silverDB:cEP00185 YP_002647223.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_002647224.1 silverDB:cEP00187 YP_002647225.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_002647226.1 silverDB:cEP00189 YP_002647227.1 silverDB:cEP00190 YP_002647228.1 silverDB:cEP00191 YP_002647229.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002647230.1 silverDB:cEP00193 YP_002647231.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_002647232.1 enterobacterial common antigen polymerase YP_002647233.1 silverDB:cEP00196 YP_002647234.1 silverDB:cEP00197 YP_002647235.1 silverDB:cEP00198 YP_002647236.1 silverDB:cEP00199 YP_002647237.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002647238.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002647239.1 silverDB:cEP00202 YP_002647240.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002647241.1 silverDB:cEP00204 YP_002647242.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002647243.1 silverDB:cEP00206 YP_002647244.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002647245.1 responsible for the influx of magnesium ions YP_002647246.1 silverDB:cEP00209 YP_002647247.1 catalyzes the hydrolysis of phosphatidylcholine YP_002647248.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_002647249.1 silverDB:cEP00212 YP_002647250.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_002647251.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_002647252.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002647253.1 silverDB:cEP00216 YP_002647254.1 silverDB:cEP00217 YP_002647255.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002647256.1 silverDB:cEP00219 YP_002647257.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002647258.1 silverDB:cEP00221 YP_002647259.1 silverDB:cEP00222 YP_002647260.1 silverDB:cEP00223 YP_002647261.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; eukaryotic proteins that exhibit kinase functions YP_002647262.1 silverDB:cEP00225 YP_002647263.1 silverDB:cEP00226 YP_002647264.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_002647265.1 magnesium dependent; not involved in the Sec-independent protein export system YP_002647266.1 silverDB:cEP00229 YP_002647267.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_002647268.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002647269.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002647270.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002647271.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_002647272.1 silverDB:cEP00235 YP_002647273.1 silverDB:cEP00236 YP_002647274.1 silverDB:cEP00237 YP_002647275.1 silverDB:cEP00238 YP_002647276.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002647277.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002647278.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002647279.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002647280.1 Modulates Rho-dependent transcription termination YP_002647281.1 silverDB:cEP00244 YP_002647282.1 silverDB:cEP00245 YP_002647283.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002647284.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002647285.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002647286.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002647287.1 silverDB:cEP00250 YP_002647288.1 silverDB:cEP00251 YP_002647289.1 silverDB:cEP00252 YP_002647290.1 silverDB:cEP00253 YP_002647291.1 silverDB:cEP00254 YP_002647292.1 silverDB:cEP00255 YP_002647293.1 silverDB:cEP00256 YP_002647294.1 silverDB:cEP00257 YP_002647295.1 silverDB:cEP00258 YP_002647296.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_002647297.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_002647298.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002647299.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_002647300.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_002647301.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002647302.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_002647303.1 silverDB:cEP00266 YP_002647304.1 silverDB:cEP00267 YP_002647305.1 silverDB:cEP00268 YP_002647306.1 silverDB:cEP00269 YP_002647307.1 involved in de novo purine biosynthesis YP_002647308.1 silverDB:cEP00271 YP_002647309.1 silverDB:cEP00272 YP_002647310.1 silverDB:cEP00273 YP_002647311.1 silverDB:cEP00274 YP_002647312.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_002647313.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002647314.1 silverDB:cEP00277 YP_002647315.1 silverDB:cEP00278 YP_002647316.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002647317.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002647318.1 silverDB:cEP00281 YP_002647319.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002647320.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002647321.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002647322.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002647323.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002647324.1 silverDB:cEP00287 YP_002647325.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002647326.1 functions in MreBCD complex in some organisms YP_002647327.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002647328.1 part of cell wall structural complex MreBCD; transmembrane component YP_002647329.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002647330.1 involved in the processing of the 5'end of 16S rRNA YP_002647331.1 silverDB:cEP00294 YP_002647332.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_002647333.1 silverDB:cEP00296 YP_002647334.1 silverDB:cEP00297 YP_002647335.1 silverDB:cEP00298 YP_002647336.1 silverDB:cEP00299 YP_002647337.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_002647338.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002647339.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002647340.1 silverDB:cEP00303 YP_002647341.1 silverDB:cEP00304 YP_002647342.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002647343.1 oxidizes malate to oxaloacetate YP_002647344.1 silverDB:cEP00307 YP_002647345.1 silverDB:cEP00308 YP_002647346.1 silverDB:cEP00309 YP_002647347.1 silverDB:cEP00310 YP_002647348.1 silverDB:cEP00311 YP_002647349.1 forms a direct contact with the tRNA during translation YP_002647350.1 silverDB:cEP00313 YP_002647351.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002647352.1 silverDB:cEP00315 YP_002647353.1 silverDB:cEP00316 YP_002647354.1 silverDB:cEP00317 YP_002647355.1 silverDB:cEP00318 YP_002647356.1 silverDB:cEP00319 YP_002647357.1 silverDB:cEP00320 YP_002647358.1 silverDB:cEP00321 YP_002647359.1 silverDB:cEP00322 YP_002647360.1 silverDB:cEP00323 YP_002647361.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002647362.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002647363.1 silverDB:cEP00326 YP_002647364.1 silverDB:cEP00327 YP_002647365.1 silverDB:cEP00328 YP_002647366.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_002647367.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002647368.1 silverDB:cEP00331 YP_002647369.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_002647370.1 silverDB:cEP00333 YP_002647371.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002647372.1 silverDB:cEP00335 YP_002647373.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_002647374.1 ATP-binding subunit of a ABC toluene efflux transporter YP_002647375.1 silverDB:cEP00338 YP_002647376.1 silverDB:cEP00339 YP_002647377.1 silverDB:cEP00340 YP_002647378.1 silverDB:cEP00341 YP_002647379.1 silverDB:cEP00342 YP_002647380.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002647381.1 silverDB:cEP00344 YP_002647382.1 silverDB:cEP00345 YP_002647383.1 silverDB:cEP00346 YP_002647384.1 involved in the peptidyltransferase reaction during translation YP_002647385.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002647386.1 silverDB:cEP00349 YP_002647387.1 silverDB:cEP00350 YP_002647388.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_002647389.1 silverDB:cEP00352 YP_002647390.1 silverDB:cEP00353 YP_002647391.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002647392.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_002647393.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_002647394.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002647395.1 silverDB:cEP00358 YP_002647396.1 silverDB:cEP00359 YP_002647397.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002647398.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002647399.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002647400.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002647401.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002647402.1 silverDB:cEP00365 YP_002647403.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002647404.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_002647405.1 silverDB:cEP00368 YP_002647406.1 silverDB:cEP00369 YP_002647407.1 silverDB:cEP00370 YP_002647408.1 silverDB:cEP00371 YP_002647409.1 silverDB:cEP00372 YP_002647410.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002647411.1 silverDB:cEP00374 YP_002647412.1 silverDB:cEP00375 YP_002647413.1 silverDB:cEP00376 YP_002647414.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002647415.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002647416.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_002647417.1 silverDB:cEP00380 YP_002647418.1 silverDB:cEP00381 YP_002647419.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002647420.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002647421.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002647422.1 silverDB:cEP00385 YP_002647423.1 silverDB:cEP00386 YP_002647424.1 silverDB:cEP00387 YP_002647425.1 silverDB:cEP00388 YP_002647426.1 silverDB:cEP00389 YP_002647427.1 silverDB:cEP00390 YP_002647428.1 silverDB:cEP00391 YP_002647429.1 silverDB:cEP00392 YP_002647430.1 silverDB:cEP00393 YP_002647431.1 silverDB:cEP00394 YP_002647432.1 silverDB:cEP00395 YP_002647433.1 silverDB:cEP00396 YP_002647434.1 silverDB:cEP00397 YP_002647435.1 silverDB:cEP00398 YP_002647436.1 silverDB:cEP00399 YP_002647437.1 silverDB:cEP00400 YP_002647438.1 silverDB:cEP00401 YP_002647439.1 silverDB:cEP00402 YP_002647440.1 silverDB:cEP00403 YP_002647441.1 silverDB:cEP00404 YP_002647442.1 silverDB:cEP00405 YP_002647443.1 silverDB:cEP00406 YP_002647444.1 silverDB:cEP00407 YP_002647445.1 silverDB:cEP00408 YP_002647446.1 silverDB:cEP00409 YP_002647447.1 silverDB:cEP00410 YP_002647448.1 silverDB:cEP00411 YP_002647449.1 silverDB:cEP00412 YP_002647450.1 silverDB:cEP00413 YP_002647451.1 this protein has no known enzymatic function YP_002647452.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_002647453.1 silverDB:cEP00416 YP_002647454.1 silverDB:cEP00417 YP_002647455.1 silverDB:cEP00418 YP_002647456.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002647457.1 synthesizes RNA primers at the replication forks YP_002647458.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002647459.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002647460.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002647461.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_002647462.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002647463.1 silverDB:cEP00426 YP_002647464.1 silverDB:cEP00427 YP_002647465.1 silverDB:cEP00428 YP_002647466.1 silverDB:cEP00429 YP_002647467.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_002647468.1 silverDB:cEP00431 YP_002647469.1 silverDB:cEP00432 YP_002647470.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_002647471.1 silverDB:cEP00434 YP_002647472.1 silverDB:cEP00435 YP_002647473.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002647474.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002647475.1 silverDB:cEP00438 YP_002647476.1 silverDB:cEP00439 YP_002647477.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002647478.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002647479.1 silverDB:cEP00442 YP_002647480.1 silverDB:cEP00443 YP_002647481.1 silverDB:cEP00444 YP_002647482.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002647483.1 silverDB:cEP00446 YP_002647484.1 silverDB:cEP00447 YP_002647485.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_002647486.1 silverDB:cEP00449 YP_002647487.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_002647488.1 silverDB:cEP00451 YP_002647489.1 silverDB:cEP00452 YP_002647490.1 silverDB:cEP00453 YP_002647491.1 silverDB:cEP00454 YP_002647492.1 silverDB:cEP00455 YP_002647493.1 silverDB:cEP00456 YP_002647494.1 silverDB:cEP00457 YP_002647495.1 silverDB:cEP00458 YP_002647496.1 silverDB:cEP00459 YP_002647497.1 silverDB:cEP00460 YP_002647498.1 silverDB:cEP00462 YP_002647499.1 silverDB:cEP00463 YP_002647500.1 silverDB:cEP00464 YP_002647501.1 silverDB:cEP00465 YP_002647502.1 silverDB:cEP00466 YP_002647503.1 silverDB:cEP00467 YP_002647504.1 silverDB:cEP00468 YP_002647505.1 silverDB:cEP00469 YP_002647506.1 silverDB:cEP00470 YP_002647507.1 silverDB:cEP00471 YP_002647508.1 silverDB:cEP00472 YP_002647509.1 silverDB:cEP00473 YP_002647510.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002647511.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; dcuB YP_002647512.1 catalyzes the formation of fumarate from aspartate YP_002647513.1 silverDB:cEP00477 YP_002647514.1 silverDB:cEP00478 YP_002647515.1 silverDB:cEP00479 YP_002647516.1 silverDB:cEP00480 YP_002647517.1 silverDB:cEP00481 YP_002647518.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002647519.1 silverDB:cEP00483 YP_002647520.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_002647521.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002647522.1 silverDB:cEP00486 YP_002647523.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002647524.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002647525.1 silverDB:cEP00489 YP_002647526.1 silverDB:cEP00491 YP_002647527.1 silverDB:cEP00492 YP_002647528.1 silverDB:cEP00494 YP_002647529.1 silverDB:cEP00495 YP_002647530.1 possibly involved in cell wall synthesis YP_002647531.1 silverDB:cEP00497 YP_002647532.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002647533.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002647534.1 Stimulates the elongation of poly(A) tails YP_002647535.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002647536.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_002647537.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_002647538.1 silverDB:cEP00504 YP_002647539.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002647540.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_002647541.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002647542.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_002647543.1 silverDB:cEP00510 YP_002647544.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_002647545.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002647546.1 binds single-stranded DNA at the primosome assembly site YP_002647547.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002647548.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002647549.1 silverDB:cEP00516 YP_002647550.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_002647551.1 silverDB:cEP00518 YP_002647552.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_002647553.1 silverDB:cEP00521 YP_002647554.1 silverDB:cEP00522 YP_002647555.1 silverDB:cEP00523 YP_002647556.1 silverDB:cEP00524 YP_002647557.1 silverDB:cEP00525 YP_002647558.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002647559.1 silverDB:cEP00527 YP_002647560.1 silverDB:cEP00528 YP_002647561.1 silverDB:cEP00529 YP_002647562.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_002647563.1 silverDB:cEP00531 YP_002647564.1 silverDB:cEP00532 YP_002647565.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002647566.1 silverDB:cEP00534 YP_002647567.1 silverDB:cEP00535 YP_002647568.1 silverDB:cEP00536 YP_002647569.1 silverDB:cEP00537 YP_002647570.1 silverDB:cEP00538 YP_002647571.1 silverDB:cEP00539 YP_002647572.1 silverDB:cEP00540 YP_002647573.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002647574.1 silverDB:cEP00542 YP_002647575.1 silverDB:cEP00543 YP_002647576.1 silverDB:cEP00544 YP_002647577.1 silverDB:cEP00545 YP_002647578.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_002647579.1 silverDB:cEP00547 YP_002647580.1 silverDB:cEP00548 YP_002647581.1 silverDB:cEP00549 YP_002647582.1 silverDB:cEP00550 YP_002647583.1 silverDB:cEP00551 YP_002647584.1 silverDB:cEP00552 YP_002647585.1 silverDB:cEP00553 YP_002647586.1 silverDB:cEP00554 YP_002647587.1 silverDB:cEP00556 YP_002647588.1 silverDB:cEP00557 YP_002647589.1 silverDB:cEP00558 YP_002647590.1 silverDB:cEP00559 YP_002647591.1 silverDB:cEP00560 YP_002647592.1 silverDB:cEP00561 YP_002647593.1 silverDB:cEP00562 YP_002647594.1 involved in the import of serine and threonine coupled with the import of sodium YP_002647595.1 silverDB:cEP00564 YP_002647596.1 silverDB:cEP00565 YP_002647597.1 silverDB:cEP00566 YP_002647598.1 silverDB:cEP00567 YP_002647599.1 silverDB:cEP00568 YP_002647600.1 silverDB:cEP00569 YP_002647601.1 silverDB:cEP00570 YP_002647602.1 silverDB:cEP00571 YP_002647603.1 silverDB:cEP00572 YP_002647604.1 possibly involved in transport of pyrroloquinoline quinone transport YP_002647605.1 Required in the synthesis of PPQ, but its exact function is unknown YP_002647606.1 silverDB:cEP00575 YP_002647607.1 silverDB:cEP00576 YP_002647608.1 silverDB:cEP00577 YP_002647609.1 silverDB:cEP00578 YP_002647610.1 silverDB:cEP00579 YP_002647611.1 silverDB:cEP00580 YP_002647612.1 silverDB:cEP00581 YP_002647613.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_002647614.1 regulator for glucitol utilization YP_002647615.1 regulates genes involved in glucitol utilization YP_002647616.1 silverDB:cEP00585 YP_002647617.1 silverDB:cEP00586 YP_002647618.1 silverDB:cEP00587 YP_002647619.1 silverDB:cEP00588 YP_002647620.1 silverDB:cEP00589 YP_002647621.1 silverDB:cEP00590 YP_002647622.1 silverDB:cEP00591 YP_002647623.1 silverDB:cEP00592 YP_002647624.1 silverDB:cEP00593 YP_002647625.1 silverDB:cEP00594 YP_002647626.1 silverDB:cEP00595 YP_002647627.1 silverDB:cEP00596 YP_002647628.1 silverDB:cEP00597 YP_002647629.1 silverDB:cEP00598 YP_002647630.1 silverDB:cEP00599 YP_002647631.1 silverDB:cEP00600 YP_002647632.1 silverDB:cEP00601 YP_002647633.1 silverDB:cEP00602 YP_002647634.1 silverDB:cEP00603 YP_002647635.1 silverDB:cEP00604 YP_002647636.1 silverDB:cEP00605 YP_002647637.1 silverDB:cEP00606 YP_002647638.1 silverDB:cEP00607 YP_002647639.1 silverDB:cEP00608 YP_002647640.1 silverDB:cEP00609 YP_002647641.1 silverDB:cEP00610 YP_002647642.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_002647643.1 silverDB:cEP00612 YP_002647644.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_002647645.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_002647646.1 silverDB:cEP00615 YP_002647647.1 silverDB:cEP00616 YP_002647648.1 silverDB:cEP00617 YP_002647649.1 silverDB:cEP00618 YP_002647650.1 silverDB:cEP00619 YP_002647651.1 silverDB:cEP00620 YP_002647652.1 silverDB:cEP00621 YP_002647653.1 silverDB:cEP00622 YP_002647654.1 silverDB:cEP00623 YP_002647655.1 silverDB:cEP00624 YP_002647656.1 silverDB:cEP00625 YP_002647657.1 silverDB:cEP00626 YP_002647658.1 silverDB:cEP00627 YP_002647659.1 silverDB:cEP00628 YP_002647660.1 silverDB:cEP00629 YP_002647661.1 silverDB:cEP00630 YP_002647662.1 silverDB:cEP00631 YP_002647663.1 silverDB:cEP00632 YP_002647664.1 silverDB:cEP00633 YP_002647665.1 silverDB:cEP00634 YP_002647666.1 silverDB:cEP00635 YP_002647667.1 silverDB:cEP00636 YP_002647668.1 silverDB:cEP00637 YP_002647669.1 silverDB:cEP00638 YP_002647670.1 silverDB:cEP00639 YP_002647671.1 silverDB:cEP00640 YP_002647672.1 silverDB:cEP00641 YP_002647673.1 silverDB:cEP00642 YP_002647674.1 silverDB:cEP00643 YP_002647675.1 silverDB:cEP00644 YP_002647676.1 silverDB:cEP00645 YP_002647677.1 silverDB:cEP00646 YP_002647678.1 silverDB:cEP00647 YP_002647679.1 silverDB:cEP00648 YP_002647680.1 silverDB:cEP00649 YP_002647681.1 silverDB:cEP00650 YP_002647682.1 silverDB:cEP00651 YP_002647683.1 silverDB:cEP00652 YP_002647684.1 silverDB:cEP00653 YP_002647685.1 silverDB:cEP00654 YP_002647686.1 silverDB:cEP00655 YP_002647687.1 silverDB:cEP00656 YP_002647688.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002647689.1 silverDB:cEP00658 YP_002647690.1 silverDB:cEP00659 YP_002647691.1 silverDB:cEP00660 YP_002647692.1 silverDB:cEP00661 YP_002647693.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002647694.1 silverDB:cEP00663 YP_002647695.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002647696.1 silverDB:cEP00665 YP_002647697.1 silverDB:cEP00666 YP_002647698.1 silverDB:cEP00667 YP_002647699.1 catalyzes the formation of serine from O-phosphoserine YP_002647700.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002647701.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_002647702.1 silverDB:cEP00671 YP_002647703.1 silverDB:cEP00672 YP_002647704.1 silverDB:cEP00673 YP_002647705.1 silverDB:cEP00674 YP_002647706.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_002647707.1 silverDB:cEP00676 YP_002647708.1 silverDB:cEP00677 YP_002647709.1 silverDB:cEP00678 YP_002647710.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_002647711.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002647712.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_002647713.1 silverDB:cEP00683 YP_002647714.1 silverDB:cEP00684 YP_002647715.1 silverDB:cEP00685 YP_002647716.1 silverDB:cEP00686 YP_002647717.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002647718.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002647719.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002647720.1 silverDB:cEP00690 YP_002647721.1 silverDB:cEP00691 YP_002647722.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002647723.1 silverDB:cEP00693 YP_002647724.1 silverDB:cEP00695 YP_002647725.1 silverDB:cEP00696 YP_002647726.1 silverDB:cEP00697 YP_002647727.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002647728.1 silverDB:cEP00699 YP_002647729.1 silverDB:cEP00700 YP_002647730.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002647731.1 lipoprotein signal peptidase; transmembrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002647732.1 silverDB:cEP00703 YP_002647733.1 silverDB:cEP00704 YP_002647734.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002647735.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002647736.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002647737.1 silverDB:cEP00708 YP_002647738.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_002647739.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_002647740.1 protein associated with Co2+ and Mg2+ efflux YP_002647741.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002647742.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002647743.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_002647744.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002647745.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002647746.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_002647747.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_002647748.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_002647749.1 silverDB:cEP00720 YP_002647750.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_002647751.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002647752.1 silverDB:cEP00723 YP_002647753.1 silverDB:cEP00724 YP_002647754.1 activates sgrS under glucose-phosphate stress conditions YP_002647755.1 silverDB:cEP00726 YP_002647756.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002647757.1 silverDB:cEP00728 YP_002647758.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002647759.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002647760.1 silverDB:cEP00731 YP_002647761.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002647762.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002647763.1 silverDB:cEP00734 YP_002647764.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002647765.1 silverDB:cEP00736 YP_002647766.1 membrane bound cell division protein at septum containing leucine zipper motif YP_002647767.1 silverDB:cEP00738 YP_002647768.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002647769.1 silverDB:cEP00740 YP_002647770.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002647771.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002647772.1 transmembrane protein involved in stabilizing FstZ ring during cell division YP_002647773.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002647774.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002647775.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002647776.1 involved in septum formation YP_002647777.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally eukaryotic actin; binds directly to the cell membrane YP_002647778.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002647779.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002647780.1 silverDB:cEP00751 YP_002647781.1 secM translational pause allows for the initiation of secA translation YP_002647782.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002647783.1 silverDB:cEP00754 YP_002647784.1 silverDB:cEP00755 YP_002647785.1 silverDB:cEP00756 YP_002647786.1 silverDB:cEP00757 YP_002647787.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells YP_002647788.1 silverDB:cEP00759 YP_002647789.1 silverDB:cEP00760 YP_002647790.1 silverDB:cEP00761 YP_002647791.1 silverDB:cEP00762 YP_002647792.1 silverDB:cEP00763 YP_002647793.1 silverDB:cEP00764 YP_002647794.1 silverDB:cEP00765 YP_002647795.1 silverDB:cEP00766 YP_002647796.1 silverDB:cEP00767 YP_002647797.1 silverDB:cEP00768 YP_002647798.1 silverDB:cEP00769 YP_002647799.1 silverDB:cEP00770 YP_002647800.1 silverDB:cEP00771 YP_002647801.1 silverDB:cEP00772 YP_002647802.1 silverDB:cEP00773 YP_002647803.1 silverDB:cEP00774 YP_002647804.1 silverDB:cEP00775 YP_002647805.1 silverDB:cEP00776 YP_002647806.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002647807.1 silverDB:cEP00778 YP_002647808.1 silverDB:cEP00779 YP_002647809.1 silverDB:cEP00780 YP_002647810.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002647811.1 silverDB:cEP00783 YP_002647812.1 involved in regulation of beta-lactamase; signaling protein YP_002647813.1 silverDB:cEP00785 YP_002647814.1 silverDB:cEP00786 YP_002647815.1 silverDB:cEP00787 YP_002647816.1 silverDB:cEP00788 YP_002647817.1 silverDB:cEP00789 YP_002647818.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002647819.1 silverDB:cEP00791 YP_002647820.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002647821.1 silverDB:cEP00793 YP_002647822.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002647823.1 silverDB:cEP00795 YP_002647824.1 silverDB:cEP00796 YP_002647825.1 silverDB:cEP00797 YP_002647826.1 silverDB:cEP00798 YP_002647827.1 silverDB:cEP00799 YP_002647828.1 silverDB:cEP00800 YP_002647829.1 silverDB:cEP00801 YP_002647830.1 silverDB:cEP00802 YP_002647831.1 silverDB:cEP00803 YP_002647832.1 silverDB:cEP00804 YP_002647833.1 silverDB:cEP00805 YP_002647834.1 silverDB:cEP00806 YP_002647835.1 silverDB:cEP00807 YP_002647836.1 silverDB:cEP00808 YP_002647837.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate YP_002647838.1 silverDB:cEP00810 YP_002647839.1 silverDB:cEP00811 YP_002647840.1 silverDB:cEP00812 YP_002647841.1 silverDB:cEP00813 YP_002647842.1 silverDB:cEP00814 YP_002647843.1 silverDB:cEP00815 YP_002647844.1 silverDB:cEP00816 YP_002647845.1 silverDB:cEP00817 YP_002647846.1 silverDB:cEP00818 YP_002647847.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002647848.1 silverDB:cEP00820 YP_002647849.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002647850.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002647851.1 silverDB:cEP00823 YP_002647852.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_002647853.1 silverDB:cEP00825 YP_002647854.1 silverDB:cEP00826 YP_002647855.1 silverDB:cEP00827 YP_002647856.1 silverDB:cEP00828 YP_002647857.1 silverDB:cEP00829 YP_002647858.1 silverDB:cEP00830 YP_002647859.1 silverDB:cEP00831 YP_002647860.1 silverDB:cEP00832 YP_002647861.1 silverDB:cEP00833 YP_002647862.1 silverDB:cEP00834 YP_002647863.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_002647864.1 silverDB:cEP00836 YP_002647865.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_002647866.1 silverDB:cEP00838 YP_002647867.1 silverDB:cEP00839 YP_002647868.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002647869.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002647870.1 silverDB:cEP00842 YP_002647871.1 silverDB:cEP00843 YP_002647872.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_002647873.1 silverDB:cEP00845 YP_002647874.1 silverDB:cEP00846 YP_002647875.1 silverDB:cEP00847 YP_002647876.1 silverDB:cEP00848 YP_002647877.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002647878.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_002647879.1 silverDB:cEP00851 YP_002647880.1 silverDB:cEP00852 YP_002647881.1 silverDB:cEP00853 YP_002647882.1 silverDB:cEP00854 YP_002647883.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_002647884.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_002647885.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_002647886.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002647887.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002647888.1 silverDB:cEP00860 YP_002647889.1 silverDB:cEP00861 YP_002647890.1 silverDB:cEP00862 YP_002647891.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002647892.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_002647893.1 protease Do; required at high temperature; degrades damaged proteins YP_002647894.1 silverDB:cEP00866 YP_002647895.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002647896.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002647897.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002647898.1 silverDB:cEP00870 YP_002647899.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002647900.1 Catalyzes the phosphorylation of UMP to UDP YP_002647901.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally tRNAs YP_002647902.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002647903.1 silverDB:cEP00875 YP_002647904.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_002647905.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_002647906.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_002647907.1 silverDB:cEP00879 YP_002647908.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002647909.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002647910.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002647911.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_002647912.1 silverDB:cEP00884 YP_002647913.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002647914.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002647915.1 silverDB:cEP00887 YP_002647916.1 silverDB:cEP00888 YP_002647917.1 silverDB:cEP00889 YP_002647918.1 silverDB:cEP00890 YP_002647919.1 silverDB:cEP00891 YP_002647920.1 silverDB:cEP00892 YP_002647921.1 silverDB:cEP00893 YP_002647922.1 silverDB:cEP00894 YP_002647923.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002647924.1 silverDB:cEP00896 YP_002647925.1 silverDB:cEP00897 YP_002647926.1 silverDB:cEP00898 YP_002647927.1 part of the MetNIQ methionine uptake system YP_002647928.1 part of the metNIQ transport system for methionine YP_002647929.1 silverDB:cEP00901 YP_002647930.1 silverDB:cEP00902 YP_002647931.1 silverDB:cEP00903 YP_002647932.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002647933.1 silverDB:cEP00905 YP_002647934.1 silverDB:cEP00906 YP_002647935.1 silverDB:cEP00907 YP_002647936.1 silverDB:cEP00908 YP_002647937.1 silverDB:cEP00909 YP_002647938.1 silverDB:cEP00910 YP_002647939.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_002647940.1 silverDB:cEP00912 YP_002647941.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_002647942.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_002647943.1 silverDB:cEP00915 YP_002647944.1 silverDB:cEP00916 YP_002647945.1 silverDB:cEP00917 YP_002647946.1 silverDB:cEP00918 YP_002647947.1 silverDB:cEP00919 YP_002647948.1 silverDB:cEP00920 YP_002647949.1 silverDB:cEP00921 YP_002647950.1 silverDB:cEP00922 YP_002647951.1 silverDB:cEP00923 YP_002647952.1 silverDB:cEP00924 YP_002647953.1 silverDB:cEP00925 YP_002647954.1 silverDB:cEP00926 YP_002647955.1 membrane protein involved in the flagellar export apparatus YP_002647956.1 silverDB:cEP00928 YP_002647957.1 silverDB:cEP00929 YP_002647958.1 silverDB:cEP00930 YP_002647959.1 silverDB:cEP00931 YP_002647960.1 silverDB:cEP00932 YP_002647961.1 silverDB:cEP00933 YP_002647962.1 silverDB:cEP00934 YP_002647963.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002647964.1 silverDB:cEP00936 YP_002647965.1 silverDB:cEP00937 YP_002647966.1 silverDB:cEP00938 YP_002647967.1 silverDB:cEP00939 YP_002647968.1 silverDB:cEP00940 YP_002647969.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002647970.1 silverDB:cEP00942 YP_002647971.1 silverDB:cEP00943 YP_002647972.1 silverDB:cEP00944 YP_002647973.1 silverDB:cEP00945 YP_002647974.1 silverDB:cEP00946 YP_002647975.1 silverDB:cEP00947 YP_002647976.1 silverDB:cEP00948 YP_002647977.1 silverDB:cEP00949 YP_002647978.1 silverDB:cEP00950 YP_002647979.1 silverDB:cEP00951 YP_002647980.1 silverDB:cEP00952 YP_002647981.1 silverDB:cEP00953 YP_002647982.1 silverDB:cEP00954 YP_002647983.1 silverDB:cEP00955 YP_002647984.1 silverDB:cEP00956 YP_002647985.1 silverDB:cEP00957 YP_002647986.1 silverDB:cEP00958 YP_002647987.1 silverDB:cEP00959 YP_002647988.1 silverDB:cEP00960 YP_002647989.1 silverDB:cEP00961 YP_002647990.1 silverDB:cEP00962 YP_002647991.1 silverDB:cEP00963 YP_002647992.1 silverDB:cEP00964 YP_002647993.1 silverDB:cEP00965 YP_002647994.1 silverDB:cEP00966 YP_002647995.1 flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002647996.1 silverDB:cEP00968 YP_002647997.1 silverDB:cEP00969 YP_002647998.1 silverDB:cEP00970 YP_002647999.1 silverDB:cEP00971 YP_002648000.1 silverDB:cEP00972 YP_002648001.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002648002.1 silverDB:cEP00974 YP_002648003.1 silverDB:cEP00975 YP_002648004.1 silverDB:cEP00976 YP_002648005.1 silverDB:cEP00977 YP_002648006.1 silverDB:cEP00978 YP_002648007.1 silverDB:cEP00979 YP_002648008.1 silverDB:cEP00980 YP_002648009.1 silverDB:cEP00981 YP_002648010.1 silverDB:cEP00982 YP_002648011.1 silverDB:cEP00983 YP_002648012.1 silverDB:cEP00984 YP_002648013.1 silverDB:cEP00985 YP_002648014.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002648015.1 silverDB:cEP00988 YP_002648016.1 silverDB:cEP00989 YP_002648017.1 silverDB:cEP00990 YP_002648018.1 silverDB:cEP00991 YP_002648019.1 silverDB:cEP00992 YP_002648020.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002648021.1 silverDB:cEP00994 YP_002648022.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002648023.1 silverDB:cEP00996 YP_002648024.1 silverDB:cEP00997 YP_002648025.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002648026.1 silverDB:cEP00999 YP_002648027.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_002648028.1 involved in the reduction of the SoxR iron-sulfur cluster YP_002648029.1 silverDB:cEP01002 YP_002648030.1 silverDB:cEP01003 YP_002648031.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002648032.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_002648033.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002648034.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002648035.1 silverDB:cEP01008 YP_002648036.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002648037.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002648038.1 silverDB:cEP01011 YP_002648039.1 silverDB:cEP01012 YP_002648040.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002648041.1 silverDB:cEP01014 YP_002648042.1 silverDB:cEP01015 YP_002648043.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_002648044.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002648045.1 silverDB:cEP01018 YP_002648046.1 silverDB:cEP01019 YP_002648047.1 silverDB:cEP01020 YP_002648048.1 silverDB:cEP01021 YP_002648049.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_002648050.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002648051.1 silverDB:cEP01024 YP_002648052.1 silverDB:cEP01025 YP_002648053.1 silverDB:cEP01026 YP_002648054.1 silverDB:cEP01027 YP_002648055.1 silverDB:cEP01028 YP_002648056.1 regulates the expression of the iscRSUA operon YP_002648057.1 silverDB:cEP01030 YP_002648058.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002648059.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_002648060.1 silverDB:cEP01033 YP_002648061.1 silverDB:cEP01034 YP_002648062.1 silverDB:cEP01035 YP_002648063.1 silverDB:cEP01036 YP_002648064.1 silverDB:cEP01037 YP_002648065.1 silverDB:cEP01038 YP_002648066.1 silverDB:cEP01039 YP_002648067.1 silverDB:cEP01040 YP_002648068.1 silverDB:cEP01041 YP_002648069.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_002648070.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002648071.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002648072.1 silverDB:cEP01045 YP_002648073.1 silverDB:cEP01046 YP_002648074.1 silverDB:cEP01047 YP_002648075.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002648076.1 silverDB:cEP01049 YP_002648077.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_002648078.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002648079.1 silverDB:cEP01052 YP_002648080.1 silverDB:cEP01053 YP_002648081.1 silverDB:cEP01054 YP_002648082.1 silverDB:cEP01055 YP_002648083.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002648084.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002648085.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002648086.1 silverDB:cEP01059 YP_002648087.1 silverDB:cEP01060 YP_002648088.1 silverDB:cEP01061 YP_002648089.1 silverDB:cEP01062 YP_002648090.1 silverDB:cEP01063 YP_002648091.1 silverDB:cEP01064 YP_002648092.1 silverDB:cEP01065 YP_002648093.1 silverDB:cEP01066 YP_002648094.1 silverDB:cEP01067 YP_002648095.1 silverDB:cEP01068 YP_002648096.1 silverDB:cEP01069 YP_002648097.1 silverDB:cEP01070 YP_002648098.1 silverDB:cEP01071 YP_002648099.1 silverDB:cEP01072 YP_002648100.1 silverDB:cEP01074 YP_002648101.1 silverDB:cEP01075 YP_002648102.1 silverDB:cEP01076 YP_002648103.1 silverDB:cEP01077 YP_002648104.1 silverDB:cEP01078 YP_002648105.1 silverDB:cEP01079 YP_002648106.1 silverDB:cEP01080 YP_002648107.1 with TehA confers resistance to tellurite YP_002648108.1 silverDB:cEP01082 YP_002648109.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002648110.1 silverDB:cEP01084 YP_002648111.1 silverDB:cEP01085 YP_002648112.1 silverDB:cEP01086 YP_002648113.1 silverDB:cEP01087 YP_002648114.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002648115.1 silverDB:cEP01089 YP_002648116.1 silverDB:cEP01090 YP_002648117.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_002648118.1 silverDB:cEP01092 YP_002648119.1 silverDB:cEP01093 YP_002648120.1 silverDB:cEP01095 YP_002648121.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002648122.1 negative transcriptional regulator of the gcvTHP operon YP_002648123.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002648124.1 silverDB:cEP01099 YP_002648125.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002648126.1 silverDB:cEP01101 YP_002648127.1 silverDB:cEP01102 YP_002648128.1 silverDB:cEP01104 YP_002648129.1 silverDB:cEP01105 YP_002648130.1 silverDB:cEP01106 YP_002648131.1 silverDB:cEP01107 YP_002648132.1 silverDB:cEP01108 YP_002648133.1 silverDB:cEP01109 YP_002648134.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002648135.1 silverDB:cEP01111 YP_002648136.1 silverDB:cEP01112 YP_002648137.1 silverDB:cEP01113 YP_002648138.1 silverDB:cEP01114 YP_002648139.1 silverDB:cEP01115 YP_002648140.1 silverDB:cEP01116 YP_002648141.1 silverDB:cEP01117 YP_002648142.1 silverDB:cEP01118 YP_002648143.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002648144.1 silverDB:cEP01120 YP_002648145.1 silverDB:cEP01121 YP_002648146.1 silverDB:cEP01122 YP_002648147.1 silverDB:cEP01123 YP_002648148.1 silverDB:cEP01124 YP_002648149.1 silverDB:cEP01125 YP_002648150.1 silverDB:cEP01126 YP_002648151.1 silverDB:cEP01127 YP_002648152.1 silverDB:cEP01128 YP_002648153.1 silverDB:cEP01129 YP_002648154.1 silverDB:cEP01130 YP_002648155.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002648156.1 silverDB:cEP01132 YP_002648157.1 silverDB:cEP01133 YP_002648158.1 silverDB:cEP01134 YP_002648159.1 silverDB:cEP01135 YP_002648160.1 silverDB:cEP01136 YP_002648161.1 silverDB:cEP01137 YP_002648162.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_002648163.1 silverDB:cEP01139 YP_002648164.1 silverDB:cEP01140 YP_002648165.1 silverDB:cEP01141 YP_002648166.1 silverDB:cEP01142 YP_002648167.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002648168.1 phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_002648169.1 silverDB:cEP01145 YP_002648170.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_002648171.1 silverDB:cEP01147 YP_002648172.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002648173.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; ligase LigB YP_002648174.1 silverDB:cEP01150 YP_002648175.1 silverDB:cEP01151 YP_002648176.1 silverDB:cEP01152 YP_002648177.1 silverDB:cEP01153 YP_002648178.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002648179.1 silverDB:cEP01155 YP_002648180.1 silverDB:cEP01156 YP_002648181.1 silverDB:cEP01157 YP_002648182.1 silverDB:cEP01158 YP_002648183.1 silverDB:cEP01159 YP_002648184.1 silverDB:cEP01160 YP_002648185.1 silverDB:cEP01161 YP_002648186.1 silverDB:cEP01162 YP_002648187.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002648188.1 silverDB:cEP01164 YP_002648189.1 silverDB:cEP01165 YP_002648190.1 silverDB:cEP01166 YP_002648191.1 silverDB:cEP01167 YP_002648192.1 silverDB:cEP01168 YP_002648193.1 silverDB:cEP01169 YP_002648194.1 silverDB:cEP01170 YP_002648195.1 silverDB:cEP01171 YP_002648196.1 silverDB:cEP01172 YP_002648197.1 silverDB:cEP01173 YP_002648198.1 silverDB:cEP01174 YP_002648199.1 silverDB:cEP01175 YP_002648200.1 silverDB:cEP01176 YP_002648201.1 silverDB:cEP01177 YP_002648202.1 silverDB:cEP01178 YP_002648203.1 silverDB:cEP01179 YP_002648204.1 silverDB:cEP01180 YP_002648205.1 silverDB:cEP01181 YP_002648206.1 silverDB:cEP01182 YP_002648207.1 silverDB:cEP01183 YP_002648208.1 silverDB:cEP01184 YP_002648209.1 silverDB:cEP01185 YP_002648210.1 silverDB:cEP01186 YP_002648211.1 silverDB:cEP01187 YP_002648212.1 silverDB:cEP01188 YP_002648213.1 silverDB:cEP01189 YP_002648214.1 silverDB:cEP01190 YP_002648215.1 silverDB:cEP01191 YP_002648216.1 silverDB:cEP01192 YP_002648217.1 silverDB:cEP01193 YP_002648218.1 silverDB:cEP01194 YP_002648219.1 silverDB:cEP01195 YP_002648220.1 silverDB:cEP01196 YP_002648221.1 silverDB:cEP01197 YP_002648222.1 silverDB:cEP01198 YP_002648223.1 silverDB:cEP01199 YP_002648224.1 silverDB:cEP01200 YP_002648225.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002648226.1 silverDB:cEP01202 YP_002648227.1 silverDB:cEP01203 YP_002648228.1 silverDB:cEP01204 YP_002648229.1 silverDB:cEP01205 YP_002648230.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002648231.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; LAS metallopeptidases; forms a dimer in periplasm YP_002648232.1 silverDB:cEP01208 YP_002648233.1 silverDB:cEP01209 YP_002648234.1 silverDB:cEP01210 YP_002648235.1 silverDB:cEP01211 YP_002648236.1 silverDB:cEP01212 YP_002648237.1 silverDB:cEP01213 YP_002648238.1 silverDB:cEP01214 YP_002648239.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002648240.1 silverDB:cEP01217 YP_002648241.1 silverDB:cEP01218 YP_002648242.1 silverDB:cEP01219 YP_002648243.1 silverDB:cEP01220 YP_002648244.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_002648245.1 silverDB:cEP01222 YP_002648246.1 silverDB:cEP01224 YP_002648247.1 silverDB:cEP01225 YP_002648248.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002648249.1 silverDB:cEP01227 YP_002648250.1 silverDB:cEP01228 YP_002648251.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002648252.1 silverDB:cEP01230 YP_002648253.1 silverDB:cEP01231 YP_002648254.1 membrane protein required for colicin V production YP_002648255.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002648256.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_002648257.1 silverDB:cEP01235 YP_002648258.1 silverDB:cEP01236 YP_002648259.1 silverDB:cEP01237 YP_002648260.1 silverDB:cEP01238 YP_002648261.1 silverDB:cEP01239 YP_002648262.1 silverDB:cEP01240 YP_002648263.1 silverDB:cEP01241 YP_002648264.1 silverDB:cEP01242 YP_002648265.1 silverDB:cEP01243 YP_002648266.1 silverDB:cEP01244 YP_002648267.1 silverDB:cEP01245 YP_002648268.1 silverDB:cEP01246 YP_002648269.1 silverDB:cEP01247 YP_002648270.1 silverDB:cEP01248 YP_002648271.1 silverDB:cEP01249 YP_002648272.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002648273.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002648274.1 silverDB:cEP01252 YP_002648275.1 silverDB:cEP01253 YP_002648276.1 silverDB:cEP01254 YP_002648277.1 silverDB:cEP01255 YP_002648278.1 silverDB:cEP01256 YP_002648279.1 silverDB:cEP01257 YP_002648280.1 silverDB:cEP01258 YP_002648281.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002648282.1 silverDB:cEP01260 YP_002648283.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648284.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002648285.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_002648286.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648287.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_002648288.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648289.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648290.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648291.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648292.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648293.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002648294.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648295.1 Catalyzes the transfer of electrons from NADH to quinone YP_002648296.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_002648297.1 silverDB:cEP01275 YP_002648298.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002648299.1 silverDB:cEP01277 YP_002648300.1 silverDB:cEP01278 YP_002648301.1 silverDB:cEP01279 YP_002648302.1 silverDB:cEP01280 YP_002648303.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_002648304.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002648305.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002648306.1 silverDB:cEP01284 YP_002648307.1 Involved in ubiquinone biosynthesis YP_002648308.1 negatively supercoils closed circular double-stranded DNA YP_002648309.1 silverDB:cEP01287 YP_002648310.1 silverDB:cEP01288 YP_002648311.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_002648312.1 silverDB:cEP01290 YP_002648313.1 silverDB:cEP01291 YP_002648314.1 silverDB:cEP01292 YP_002648315.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_002648316.1 silverDB:cEP01294 YP_002648317.1 silverDB:cEP01297 YP_002648318.1 silverDB:cEP01298 YP_002648319.1 silverDB:cEP01299 YP_002648320.1 silverDB:cEP01300 YP_002648321.1 silverDB:cEP01301 YP_002648322.1 silverDB:cEP01302 YP_002648323.1 silverDB:cEP01303 YP_002648324.1 silverDB:cEP01304 YP_002648325.1 silverDB:cEP01305 YP_002648326.1 silverDB:cEP01306 YP_002648327.1 silverDB:cEP01307 YP_002648328.1 silverDB:cEP01308 YP_002648329.1 silverDB:cEP01309 YP_002648330.1 silverDB:cEP01310 YP_002648331.1 silverDB:cEP01311 YP_002648332.1 silverDB:cEP01312 YP_002648333.1 silverDB:cEP01313 YP_002648334.1 silverDB:cEP01314 YP_002648335.1 silverDB:cEP01315 YP_002648336.1 silverDB:cEP01317 YP_002648337.1 silverDB:cEP01318 YP_002648338.1 silverDB:cEP01319 YP_002648339.1 silverDB:cEP01320 YP_002648340.1 silverDB:cEP01321 YP_002648341.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_002648342.1 silverDB:cEP01323 YP_002648343.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_002648344.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002648345.1 silverDB:cEP01326 YP_002648346.1 silverDB:cEP01327 YP_002648347.1 silverDB:cEP01328 YP_002648348.1 silverDB:cEP01329 YP_002648349.1 silverDB:cEP01330 YP_002648350.1 silverDB:cEP01331 YP_002648351.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_002648352.1 silverDB:cEP01333 YP_002648353.1 silverDB:cEP01334 YP_002648354.1 silverDB:cEP01335 YP_002648355.1 silverDB:cEP01336 YP_002648356.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_002648357.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; PfkB; forms homodimers YP_002648358.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002648359.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002648360.1 silverDB:cEP01341 YP_002648361.1 silverDB:cEP01342 YP_002648362.1 silverDB:cEP01343 YP_002648363.1 silverDB:cEP01344 YP_002648364.1 silverDB:cEP01345 YP_002648365.1 silverDB:cEP01346 YP_002648366.1 silverDB:cEP01347 YP_002648367.1 silverDB:cEP01348 YP_002648368.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002648369.1 silverDB:cEP01350 YP_002648370.1 silverDB:cEP01355 YP_002648371.1 silverDB:cEP01356 YP_002648372.1 silverDB:cEP01357 YP_002648373.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002648374.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002648375.1 silverDB:cEP01360 YP_002648376.1 silverDB:cEP01361 YP_002648377.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002648378.1 silverDB:cEP01363 YP_002648379.1 silverDB:cEP01364 YP_002648380.1 silverDB:cEP01365 YP_002648381.1 silverDB:cEP01366 YP_002648382.1 silverDB:cEP01367 YP_002648383.1 silverDB:cEP01368 YP_002648384.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002648385.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_002648386.1 silverDB:cEP01371 YP_002648387.1 silverDB:cEP01372 YP_002648388.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_002648389.1 silverDB:cEP01374 YP_002648390.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_002648391.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002648392.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_002648393.1 silverDB:cEP01378 YP_002648394.1 silverDB:cEP01379 YP_002648395.1 silverDB:cEP01380 YP_002648396.1 silverDB:cEP01381 YP_002648397.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002648398.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002648399.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_002648400.1 silverDB:cEP01385 YP_002648401.1 silverDB:cEP01386 YP_002648402.1 silverDB:cEP01387 YP_002648403.1 silverDB:cEP01388 YP_002648404.1 silverDB:cEP01389 YP_002648405.1 silverDB:cEP01390 YP_002648406.1 silverDB:cEP01391 YP_002648407.1 silverDB:cEP01392 YP_002648408.1 silverDB:cEP01393 YP_002648409.1 silverDB:cEP01394 YP_002648410.1 silverDB:cEP01395 YP_002648411.1 silverDB:cEP01396 YP_002648412.1 silverDB:cEP01397 YP_002648413.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002648414.1 silverDB:cEP01399 YP_002648415.1 silverDB:cEP01400 YP_002648416.1 silverDB:cEP01401 YP_002648417.1 silverDB:cEP01402 YP_002648418.1 silverDB:cEP01403 YP_002648419.1 silverDB:cEP01404 YP_002648420.1 silverDB:cEP01405 YP_002648421.1 silverDB:cEP01406 YP_002648422.1 silverDB:cEP01407 YP_002648423.1 silverDB:cEP01408 YP_002648424.1 silverDB:cEP01409 YP_002648425.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002648426.1 silverDB:cEP01411 YP_002648427.1 silverDB:cEP01412 YP_002648428.1 silverDB:cEP01413 YP_002648429.1 silverDB:cEP01414 YP_002648430.1 silverDB:cEP01415 YP_002648431.1 silverDB:cEP01416 YP_002648432.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002648433.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002648434.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002648435.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002648436.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002648437.1 silverDB:cEP01422 YP_002648438.1 silverDB:cEP01423 YP_002648439.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002648440.1 silverDB:cEP01425 YP_002648441.1 silverDB:cEP01427 YP_002648442.1 silverDB:cEP01428 YP_002648443.1 silverDB:cEP01429 YP_002648444.1 silverDB:cEP01430 YP_002648445.1 silverDB:cEP01431 YP_002648446.1 silverDB:cEP01432 YP_002648447.1 silverDB:cEP01433 YP_002648448.1 silverDB:cEP01434 YP_002648449.1 silverDB:cEP01435 YP_002648450.1 silverDB:cEP01436 YP_002648451.1 silverDB:cEP01437 YP_002648452.1 silverDB:cEP01438 YP_002648453.1 silverDB:cEP01439 YP_002648454.1 silverDB:cEP01440 YP_002648455.1 silverDB:cEP01441 YP_002648456.1 silverDB:cEP01442 YP_002648457.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002648458.1 silverDB:cEP01444 YP_002648459.1 silverDB:cEP01445 YP_002648460.1 silverDB:cEP01446 YP_002648461.1 silverDB:cEP01447 YP_002648462.1 silverDB:cEP01448 YP_002648463.1 silverDB:cEP01449 YP_002648464.1 silverDB:cEP01450 YP_002648465.1 silverDB:cEP01451 YP_002648466.1 silverDB:cEP01452 YP_002648467.1 silverDB:cEP01453 YP_002648468.1 silverDB:cEP01454 YP_002648469.1 silverDB:cEP01455 YP_002648470.1 silverDB:cEP01456 YP_002648471.1 silverDB:cEP01457 YP_002648472.1 silverDB:cEP01458 YP_002648473.1 silverDB:cEP01459 YP_002648474.1 transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_002648475.1 LysR-type transcriptional regulator CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_002648476.1 silverDB:cEP01462 YP_002648477.1 silverDB:cEP01463 YP_002648478.1 silverDB:cEP01464 YP_002648479.1 silverDB:cEP01465 YP_002648480.1 silverDB:cEP01468 YP_002648481.1 silverDB:cEP01469 YP_002648482.1 silverDB:cEP01470 YP_002648483.1 silverDB:cEP01471 YP_002648484.1 silverDB:cEP01472 YP_002648485.1 silverDB:cEP01473 YP_002648486.1 silverDB:cEP01474 YP_002648487.1 silverDB:cEP01475 YP_002648488.1 silverDB:cEP01476 YP_002648489.1 silverDB:cEP01478 YP_002648490.1 silverDB:cEP01479 YP_002648491.1 silverDB:cEP01480 YP_002648492.1 silverDB:cEP01481 YP_002648493.1 silverDB:cEP01482 YP_002648494.1 silverDB:cEP01483 YP_002648495.1 silverDB:cEP01484 YP_002648496.1 silverDB:cEP01485 YP_002648497.1 silverDB:cEP01486 YP_002648498.1 silverDB:cEP01487 YP_002648499.1 silverDB:cEP01488 YP_002648500.1 silverDB:cEP01489 YP_002648501.1 silverDB:cEP01490 YP_002648502.1 silverDB:cEP01491 YP_002648503.1 silverDB:cEP01492 YP_002648504.1 silverDB:cEP01493 YP_002648505.1 silverDB:cEP01494 YP_002648506.1 silverDB:cEP01495 YP_002648507.1 silverDB:cEP01496 YP_002648508.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002648509.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_002648510.1 silverDB:cEP01499 YP_002648511.1 involved in flagellin assembly YP_002648512.1 silverDB:cEP01501 YP_002648513.1 silverDB:cEP01502 YP_002648514.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002648515.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_002648516.1 silverDB:cEP01505 YP_002648517.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_002648518.1 silverDB:cEP01507 YP_002648519.1 silverDB:cEP01508 YP_002648520.1 silverDB:cEP01509 YP_002648521.1 silverDB:cEP01510 YP_002648522.1 silverDB:cEP01511 YP_002648523.1 silverDB:cEP01512 YP_002648524.1 silverDB:cEP01513 YP_002648525.1 silverDB:cEP01515 YP_002648526.1 silverDB:cEP01516 YP_002648527.1 silverDB:cEP01517 YP_002648528.1 silverDB:cEP01518 YP_002648529.1 silverDB:cEP01519 YP_002648530.1 silverDB:cEP01520 YP_002648531.1 silverDB:cEP01521 YP_002648532.1 silverDB:cEP01522 YP_002648533.1 silverDB:cEP01523 YP_002648534.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002648535.1 silverDB:cEP01525 YP_002648536.1 silverDB:cEP01526 YP_002648537.1 silverDB:cEP01527 YP_002648538.1 silverDB:cEP01528 YP_002648539.1 silverDB:cEP01529 YP_002648540.1 silverDB:cEP01530 YP_002648541.1 silverDB:cEP01531 YP_002648542.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_002648543.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002648544.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002648545.1 silverDB:cEP01535 YP_002648546.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_002648547.1 silverDB:cEP01537 YP_002648548.1 silverDB:cEP01538 YP_002648549.1 silverDB:cEP01539 YP_002648550.1 silverDB:cEP01540 YP_002648551.1 silverDB:cEP01541 YP_002648552.1 silverDB:cEP01542 YP_002648553.1 silverDB:cEP01543 YP_002648554.1 methylates the MCP YP_002648555.1 silverDB:cEP01545 YP_002648556.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_002648557.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_002648558.1 silverDB:cEP01548 YP_002648559.1 membrane protein involved in the flagellar export apparatus YP_002648560.1 silverDB:cEP01550 YP_002648561.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002648562.1 silverDB:cEP01552 YP_002648563.1 silverDB:cEP01553 YP_002648564.1 silverDB:cEP01554 YP_002648565.1 silverDB:cEP01555 YP_002648566.1 silverDB:cEP01556 YP_002648567.1 silverDB:cEP01557 YP_002648568.1 silverDB:cEP01558 YP_002648569.1 silverDB:cEP01559 YP_002648570.1 silverDB:cEP01560 YP_002648571.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002648572.1 silverDB:cEP01562 YP_002648573.1 silverDB:cEP01563 YP_002648574.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002648575.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002648576.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002648577.1 involved in transport of zinc(II) with ZnuA and C YP_002648578.1 involved in transport of zinc(II) with ZnuA and C YP_002648579.1 involved in transport of zinc(II) with ZnuA and C YP_002648580.1 silverDB:cEP01570 YP_002648581.1 transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_002648582.1 silverDB:cEP01572 YP_002648583.1 silverDB:cEP01573 YP_002648584.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002648585.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002648586.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_002648587.1 silverDB:cEP01577 YP_002648588.1 silverDB:cEP01578 YP_002648589.1 silverDB:cEP01579 YP_002648590.1 3'-5' exonuclease activity on single or double-strand DNA YP_002648591.1 silverDB:cEP01581 YP_002648592.1 silverDB:cEP01582 YP_002648593.1 silverDB:cEP01583 YP_002648594.1 silverDB:cEP01584 YP_002648595.1 silverDB:cEP01585 YP_002648596.1 silverDB:cEP01586 YP_002648597.1 silverDB:cEP01587 YP_002648598.1 silverDB:cEP01588 YP_002648599.1 silverDB:cEP01589 YP_002648600.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002648601.1 silverDB:cEP01591 YP_002648602.1 silverDB:cEP01592 YP_002648603.1 silverDB:cEP01593 YP_002648604.1 affects solute and DNA transport through an unknown mechanism YP_002648605.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002648606.1 metalloprotease YP_002648607.1 silverDB:cEP01597 YP_002648608.1 silverDB:cEP01598 YP_002648609.1 silverDB:cEP01599 YP_002648610.1 silverDB:cEP01601 YP_002648611.1 silverDB:cEP01602 YP_002648612.1 silverDB:cEP01603 YP_002648613.1 silverDB:cEP01604 YP_002648614.1 silverDB:cEP01605 YP_002648615.1 silverDB:cEP01606 YP_002648616.1 silverDB:cEP01607 YP_002648617.1 silverDB:cEP01608 YP_002648618.1 silverDB:cEP01609 YP_002648619.1 silverDB:cEP01610 YP_002648620.1 silverDB:cEP01611 YP_002648621.1 silverDB:cEP01612 YP_002648622.1 silverDB:cEP01613 YP_002648623.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002648624.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_002648625.1 blocks the formation of polar Z-ring septums YP_002648626.1 silverDB:cEP01617 YP_002648627.1 silverDB:cEP01618 YP_002648628.1 silverDB:cEP01619 YP_002648629.1 disulfide oxidoreductase; transmembrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002648630.1 multifunctional regulator of fatty acid metabolism YP_002648631.1 silverDB:cEP01622 YP_002648632.1 catalyzes the oxidative deamination of D-amino acids YP_002648633.1 silverDB:cEP01624 YP_002648634.1 silverDB:cEP01625 YP_002648635.1 silverDB:cEP01626 YP_002648636.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_002648637.1 silverDB:cEP01628 YP_002648638.1 silverDB:cEP01629 YP_002648639.1 silverDB:cEP01630 YP_002648640.1 silverDB:cEP01632 YP_002648641.1 silverDB:cEP01633 YP_002648642.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_002648643.1 silverDB:cEP01635 YP_002648644.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_002648645.1 converts asparagine to aspartate and ammonia YP_002648646.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_002648647.1 silverDB:cEP01639 YP_002648648.1 decatenates replicating daughter chromosomes YP_002648649.1 silverDB:cEP01641 YP_002648650.1 silverDB:cEP01642 YP_002648651.1 silverDB:cEP01643 YP_002648652.1 silverDB:cEP01644 YP_002648653.1 silverDB:cEP01645 YP_002648654.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_002648655.1 silverDB:cEP01647 YP_002648656.1 silverDB:cEP01648 YP_002648657.1 silverDB:cEP01649 YP_002648658.1 silverDB:cEP01650 YP_002648659.1 silverDB:cEP01651 YP_002648660.1 silverDB:cEP01652 YP_002648661.1 silverDB:cEP01653 YP_002648662.1 silverDB:cEP01654 YP_002648663.1 silverDB:cEP01655 YP_002648664.1 silverDB:cEP01656 YP_002648665.1 silverDB:cEP01657 YP_002648666.1 silverDB:cEP01658 YP_002648667.1 silverDB:cEP01659 YP_002648668.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_002648669.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002648670.1 silverDB:cEP01663 YP_002648671.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_002648672.1 silverDB:cEP01665 YP_002648673.1 Involved in cell division; probably involved in intracellular septation YP_002648674.1 silverDB:cEP01667 YP_002648675.1 silverDB:cEP01668 YP_002648676.1 silverDB:cEP01669 YP_002648677.1 silverDB:cEP01670 YP_002648678.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002648679.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002648680.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002648681.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002648682.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002648683.1 silverDB:cEP01676 YP_002648684.1 silverDB:cEP01677 YP_002648685.1 silverDB:cEP01678 YP_002648686.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_002648687.1 silverDB:cEP01680 YP_002648688.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002648689.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002648690.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_002648691.1 silverDB:cEP01684 YP_002648692.1 Catalyzes the conversion of citrate to isocitrate YP_002648693.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_002648694.1 silverDB:cEP01687 YP_002648695.1 silverDB:cEP01688 YP_002648696.1 silverDB:cEP01689 YP_002648697.1 silverDB:cEP01690 YP_002648698.1 involved in start site selection during the initiation of translation YP_002648699.1 silverDB:cEP01692 YP_002648700.1 silverDB:cEP01693 YP_002648701.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002648702.1 silverDB:cEP01695 YP_002648703.1 silverDB:cEP01696 YP_002648704.1 silverDB:cEP01697 YP_002648705.1 silverDB:cEP01698 YP_002648706.1 silverDB:cEP01699 YP_002648707.1 silverDB:cEP01700 YP_002648708.1 silverDB:cEP01701 YP_002648709.1 silverDB:cEP01702 YP_002648710.1 silverDB:cEP01703 YP_002648711.1 silverDB:cEP01704 YP_002648712.1 silverDB:cEP01705 YP_002648713.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_002648714.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_002648715.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_002648716.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_002648717.1 silverDB:cEP01710 YP_002648718.1 silverDB:cEP01711 YP_002648719.1 silverDB:cEP01712 YP_002648720.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_002648721.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002648722.1 silverDB:cEP01715 YP_002648723.1 silverDB:cEP01716 YP_002648724.1 silverDB:cEP01717 YP_002648725.1 silverDB:cEP01718 YP_002648726.1 silverDB:cEP01719 YP_002648727.1 silverDB:cEP01720 YP_002648728.1 member of the periplasmic pilus chaperone family of proteins YP_002648729.1 silverDB:cEP01722 YP_002648730.1 silverDB:cEP01723 YP_002648731.1 silverDB:cEP01724 YP_002648732.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002648733.1 silverDB:cEP01726 YP_002648734.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_002648735.1 silverDB:cEP01728 YP_002648736.1 silverDB:cEP01729 YP_002648737.1 silverDB:cEP01730 YP_002648738.1 silverDB:cEP01731 YP_002648739.1 silverDB:cEP01732 YP_002648740.1 silverDB:cEP01733 YP_002648741.1 silverDB:cEP01734 YP_002648742.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002648743.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_002648744.1 silverDB:cEP01737 YP_002648745.1 silverDB:cEP01738 YP_002648746.1 required for growth and survival under moderately acid conditions YP_002648747.1 silverDB:cEP01740 YP_002648748.1 silverDB:cEP01741 YP_002648749.1 silverDB:cEP01743 YP_002648750.1 silverDB:cEP01744 YP_002648751.1 silverDB:cEP01745 YP_002648752.1 silverDB:cEP01746 YP_002648753.1 silverDB:cEP01747 YP_002648754.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown. YP_002648755.1 silverDB:cEP01749 YP_002648756.1 silverDB:cEP01750 YP_002648757.1 silverDB:cEP01751 YP_002648758.1 silverDB:cEP01752 YP_002648759.1 silverDB:cEP01753 YP_002648760.1 silverDB:cEP01754 YP_002648761.1 silverDB:cEP01755 YP_002648762.1 silverDB:cEP01756 YP_002648763.1 silverDB:cEP01757 YP_002648764.1 silverDB:cEP01758 YP_002648765.1 silverDB:cEP01759 YP_002648766.1 silverDB:cEP01760 YP_002648767.1 silverDB:cEP01761 YP_002648768.1 silverDB:cEP01762 YP_002648769.1 silverDB:cEP01763 YP_002648770.1 silverDB:cEP01764 YP_002648771.1 silverDB:cEP01765 YP_002648772.1 silverDB:cEP01766 YP_002648773.1 silverDB:cEP01767 YP_002648774.1 silverDB:cEP01768 YP_002648775.1 silverDB:cEP01769 YP_002648776.1 silverDB:cEP01770 YP_002648777.1 silverDB:cEP01771 YP_002648778.1 silverDB:cEP01772 YP_002648779.1 silverDB:cEP01773 YP_002648780.1 silverDB:cEP01774 YP_002648781.1 silverDB:cEP01775 YP_002648782.1 silverDB:cEP01776 YP_002648783.1 silverDB:cEP01777 YP_002648784.1 silverDB:cEP01778 YP_002648785.1 silverDB:cEP01779 YP_002648786.1 silverDB:cEP01780 YP_002648787.1 silverDB:cEP01781 YP_002648788.1 silverDB:cEP01782 YP_002648789.1 silverDB:cEP01783 YP_002648790.1 response regulator in two-component regulatory system with RstB YP_002648791.1 silverDB:cEP01785 YP_002648792.1 silverDB:cEP01786 YP_002648793.1 silverDB:cEP01787 YP_002648794.1 silverDB:cEP01788 YP_002648795.1 silverDB:cEP01789 YP_002648796.1 silverDB:cEP01790 YP_002648797.1 with UspC and UspD is involved in resistance to UV irradiation YP_002648798.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002648799.1 silverDB:cEP01793 YP_002648800.1 silverDB:cEP01794 YP_002648801.1 silverDB:cEP01795 YP_002648802.1 silverDB:cEP01796 YP_002648803.1 silverDB:cEP01797 YP_002648804.1 silverDB:cEP01798 YP_002648805.1 silverDB:cEP01799 YP_002648806.1 silverDB:cEP01800 YP_002648807.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002648808.1 silverDB:cEP01802 YP_002648809.1 silverDB:cEP01803 YP_002648810.1 catalyzes the formation of glutamate from glutamine YP_002648811.1 silverDB:cEP01805 YP_002648812.1 silverDB:cEP01806 YP_002648813.1 silverDB:cEP01807 YP_002648814.1 silverDB:cEP01808 YP_002648815.1 silverDB:cEP01809 YP_002648816.1 silverDB:cEP01810 YP_002648817.1 silverDB:cEP01811 YP_002648818.1 silverDB:cEP01812 YP_002648819.1 silverDB:cEP01813 YP_002648820.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002648821.1 silverDB:cEP01815 YP_002648822.1 silverDB:cEP01816 YP_002648823.1 silverDB:cEP01817 YP_002648824.1 silverDB:cEP01818 YP_002648825.1 silverDB:cEP01819 YP_002648826.1 silverDB:cEP01820 YP_002648827.1 silverDB:cEP01821 YP_002648828.1 silverDB:cEP01822 YP_002648829.1 silverDB:cEP01823 YP_002648830.1 silverDB:cEP01824 YP_002648831.1 silverDB:cEP01825 YP_002648832.1 silverDB:cEP01826 YP_002648833.1 silverDB:cEP01827 YP_002648834.1 silverDB:cEP01828 YP_002648835.1 silverDB:cEP01829 YP_002648836.1 silverDB:cEP01830 YP_002648837.1 silverDB:cEP01831 YP_002648838.1 silverDB:cEP01832 YP_002648839.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_002648840.1 silverDB:cEP01835 YP_002648841.1 silverDB:cEP01836 YP_002648842.1 silverDB:cEP01837 YP_002648843.1 silverDB:cEP01838 YP_002648844.1 silverDB:cEP01839 YP_002648845.1 silverDB:cEP01840 YP_002648846.1 silverDB:cEP01841 YP_002648847.1 silverDB:cEP01842 YP_002648848.1 silverDB:cEP01843 YP_002648849.1 silverDB:cEP01844 YP_002648850.1 silverDB:cEP01845 YP_002648851.1 silverDB:cEP01846 YP_002648852.1 silverDB:cEP01847 YP_002648853.1 silverDB:cEP01848 YP_002648854.1 silverDB:cEP01849 YP_002648855.1 silverDB:cEP01850 YP_002648856.1 silverDB:cEP01851 YP_002648857.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_002648858.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002648859.1 silverDB:cEP01854 YP_002648860.1 silverDB:cEP01855 YP_002648861.1 silverDB:cEP01856 YP_002648862.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_002648863.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002648864.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002648865.1 silverDB:cEP01860 YP_002648866.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_002648867.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_002648868.1 silverDB:cEP01863 YP_002648869.1 silverDB:cEP01864 YP_002648870.1 silverDB:cEP01865 YP_002648871.1 silverDB:cEP01866 YP_002648872.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002648873.1 silverDB:cEP01868 YP_002648874.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_002648875.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002648876.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_002648877.1 silverDB:cEP01872 YP_002648878.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_002648879.1 catalyzes the formation of betaine from betaine aldehyde YP_002648880.1 silverDB:cEP01875 YP_002648881.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_002648882.1 silverDB:cEP01877 YP_002648883.1 silverDB:cEP01878 YP_002648884.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002648885.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002648886.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002648887.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002648888.1 silverDB:cEP01883 YP_002648889.1 transcription regulator that can both activate or repress expression YP_002648890.1 silverDB:cEP01885 YP_002648891.1 silverDB:cEP01886 YP_002648892.1 silverDB:cEP01887 YP_002648893.1 silverDB:cEP01888 YP_002648894.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_002648895.1 silverDB:cEP01890 YP_002648896.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_002648897.1 silverDB:cEP01892 YP_002648898.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002648899.1 silverDB:cEP01894 YP_002648900.1 silverDB:cEP01895 YP_002648901.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_002648902.1 silverDB:cEP01897 YP_002648903.1 uncharacterized member of the major facilitator superfamily (MFS) YP_002648904.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_002648905.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002648906.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002648907.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002648908.1 silverDB:cEP01903 YP_002648909.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_002648910.1 silverDB:cEP01905 YP_002648911.1 silverDB:cEP01906 YP_002648912.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_002648913.1 with SufCD activates cysteine desulfurase SufS YP_002648914.1 silverDB:cEP01909 YP_002648915.1 silverDB:cEP01910 YP_002648916.1 silverDB:cEP01911 YP_002648917.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_002648918.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002648919.1 silverDB:cEP01914 YP_002648920.1 silverDB:cEP01915 YP_002648921.1 silverDB:cEP01916 YP_002648922.1 silverDB:cEP01917 YP_002648923.1 with HmuTU is involved in the transport of hemin YP_002648924.1 silverDB:cEP01919 YP_002648925.1 silverDB:cEP01920 YP_002648926.1 silverDB:cEP01921 YP_002648927.1 silverDB:cEP01922 YP_002648928.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002648929.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002648930.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002648931.1 silverDB:cEP01926 YP_002648932.1 silverDB:cEP01927 YP_002648933.1 silverDB:cEP01928 YP_002648934.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002648935.1 silverDB:cEP01930 YP_002648936.1 silverDB:cEP01931 YP_002648937.1 silverDB:cEP01932 YP_002648938.1 silverDB:cEP01933 YP_002648939.1 silverDB:cEP01934 YP_002648940.1 silverDB:cEP01935 YP_002648941.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_002648942.1 silverDB:cEP01937 YP_002648943.1 silverDB:cEP01938 YP_002648944.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_002648945.1 silverDB:cEP01940 YP_002648946.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002648947.1 3' incision activity; acts with UvrC YP_002648948.1 periplasmic protein induced by stress response via Cpx and BaeSR system; CpxP YP_002648949.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002648950.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002648951.1 silverDB:cEP01946 YP_002648952.1 silverDB:cEP01947 YP_002648953.1 silverDB:cEP01948 YP_002648954.1 silverDB:cEP01949 YP_002648955.1 silverDB:cEP01950 YP_002648956.1 silverDB:cEP01951 YP_002648957.1 silverDB:cEP01952 YP_002648958.1 silverDB:cEP01953 YP_002648959.1 silverDB:cEP01954 YP_002648960.1 silverDB:cEP01955 YP_002648961.1 silverDB:cEP01956 YP_002648962.1 silverDB:cEP01957 YP_002648963.1 silverDB:cEP01958 YP_002648964.1 silverDB:cEP01959 YP_002648965.1 silverDB:cEP01960 YP_002648966.1 silverDB:cEP01961 YP_002648967.1 silverDB:cEP01962 YP_002648968.1 silverDB:cEP01963 YP_002648969.1 silverDB:cEP01964 YP_002648970.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002648971.1 silverDB:cEP01966 YP_002648972.1 silverDB:cEP01967 YP_002648973.1 silverDB:cEP01968 YP_002648974.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is release factor 2 YP_002648975.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002648976.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002648977.1 silverDB:cEP01972 YP_002648978.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002648979.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_002648980.1 silverDB:cEP01975 YP_002648981.1 silverDB:cEP01976 YP_002648982.1 silverDB:cEP01977 YP_002648983.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002648984.1 silverDB:cEP01979 YP_002648985.1 silverDB:cEP01980 YP_002648986.1 silverDB:cEP01981 YP_002648987.1 silverDB:cEP01982 YP_002648988.1 silverDB:cEP01983 YP_002648989.1 silverDB:cEP01984 YP_002648990.1 silverDB:cEP01985 YP_002648991.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins YP_002648992.1 silverDB:cEP01987 YP_002648993.1 silverDB:cEP01988 YP_002648994.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_002648995.1 silverDB:cEP01990 YP_002648996.1 silverDB:cEP01991 YP_002648997.1 silverDB:cEP01992 YP_002648998.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. catalytic subunit of a protein translocase YP_002648999.1 silverDB:cEP01994 YP_002649000.1 silverDB:cEP01995 YP_002649001.1 silverDB:cEP01996 YP_002649002.1 silverDB:cEP01997 YP_002649003.1 silverDB:cEP01998 YP_002649004.1 silverDB:cEP01999 YP_002649005.1 silverDB:cEP02000 YP_002649006.1 silverDB:cEP02001 YP_002649007.1 silverDB:cEP02002 YP_002649008.1 silverDB:cEP02003 YP_002649009.1 silverDB:cEP02004 YP_002649010.1 silverDB:cEP02005 YP_002649011.1 silverDB:cEP02006 YP_002649012.1 silverDB:cEP02007 YP_002649013.1 silverDB:cEP02008 YP_002649014.1 silverDB:cEP02009 YP_002649015.1 silverDB:cEP02010 YP_002649016.1 silverDB:cEP02011 YP_002649017.1 silverDB:cEP02012 YP_002649018.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002649019.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_002649020.1 silverDB:cEP02015 YP_002649021.1 silverDB:cEP02016 YP_002649022.1 silverDB:cEP02017 YP_002649023.1 silverDB:cEP02018 YP_002649024.1 silverDB:cEP02019 YP_002649025.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_002649026.1 silverDB:cEP02021 YP_002649027.1 silverDB:cEP02022 YP_002649028.1 silverDB:cEP02023 YP_002649029.1 silverDB:cEP02024 YP_002649030.1 silverDB:cEP02025 YP_002649031.1 silverDB:cEP02026 YP_002649032.1 silverDB:cEP02027 YP_002649033.1 silverDB:cEP02028 YP_002649034.1 silverDB:cEP02029 YP_002649035.1 silverDB:cEP02030 YP_002649036.1 silverDB:cEP02031 YP_002649037.1 silverDB:cEP02034 YP_002649038.1 silverDB:cEP02035 YP_002649039.1 silverDB:cEP02036 YP_002649040.1 silverDB:cEP02037 YP_002649041.1 silverDB:cEP02038 YP_002649042.1 silverDB:cEP02039 YP_002649043.1 silverDB:cEP02040 YP_002649044.1 silverDB:cEP02041 YP_002649045.1 silverDB:cEP02042 YP_002649046.1 silverDB:cEP02043 YP_002649047.1 silverDB:cEP02044 YP_002649048.1 silverDB:cEP02045 YP_002649049.1 silverDB:cEP02046 YP_002649050.1 silverDB:cEP02047 YP_002649051.1 silverDB:cEP02048 YP_002649052.1 silverDB:cEP02049 YP_002649053.1 silverDB:cEP02050 YP_002649054.1 silverDB:cEP02051 YP_002649055.1 silverDB:cEP02052 YP_002649056.1 silverDB:cEP02053 YP_002649057.1 silverDB:cEP02054 YP_002649058.1 silverDB:cEP02055 YP_002649059.1 silverDB:cEP02056 YP_002649060.1 silverDB:cEP02057 YP_002649061.1 silverDB:cEP02058 YP_002649062.1 silverDB:cEP02059 YP_002649063.1 silverDB:cEP02060 YP_002649064.1 silverDB:cEP02061 YP_002649065.1 silverDB:cEP02062 YP_002649066.1 silverDB:cEP02063 YP_002649067.1 silverDB:cEP02064 YP_002649068.1 silverDB:cEP02065 YP_002649069.1 silverDB:cEP02066 YP_002649070.1 silverDB:cEP02067 YP_002649071.1 silverDB:cEP02068 YP_002649072.1 silverDB:cEP02069 YP_002649073.1 silverDB:cEP02070 YP_002649074.1 silverDB:cEP02071 YP_002649075.1 silverDB:cEP02072 YP_002649076.1 silverDB:cEP02073 YP_002649077.1 silverDB:cEP02074 YP_002649078.1 silverDB:cEP02075 YP_002649079.1 silverDB:cEP02076 YP_002649080.1 silverDB:cEP02077 YP_002649081.1 silverDB:cEP02078 YP_002649082.1 silverDB:cEP02079 YP_002649083.1 silverDB:cEP02080 YP_002649084.1 silverDB:cEP02081 YP_002649085.1 silverDB:cEP02082 YP_002649086.1 silverDB:cEP02083 YP_002649087.1 silverDB:cEP02084 YP_002649088.1 silverDB:cEP02085 YP_002649089.1 silverDB:cEP02086 YP_002649090.1 silverDB:cEP02087 YP_002649091.1 silverDB:cEP02088 YP_002649092.1 Converts isocitrate to alpha ketoglutarate YP_002649093.1 silverDB:cEP02090 YP_002649094.1 silverDB:cEP02091 YP_002649095.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002649096.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002649097.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002649098.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_002649099.1 silverDB:cEP02096 YP_002649100.1 silverDB:cEP02097 YP_002649101.1 silverDB:cEP02098 YP_002649102.1 silverDB:cEP02099 YP_002649103.1 silverDB:cEP02100 YP_002649104.1 silverDB:cEP02101 YP_002649105.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002649106.1 silverDB:cEP02103 YP_002649107.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002649108.1 silverDB:cEP02105 YP_002649109.1 silverDB:cEP02106 YP_002649110.1 silverDB:cEP02107 YP_002649111.1 silverDB:cEP02108 YP_002649112.1 silverDB:cEP02109 YP_002649113.1 silverDB:cEP02110 YP_002649114.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_002649115.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002649116.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002649117.1 involved in type III protein export during flagellum assembly YP_002649118.1 silverDB:cEP02115 YP_002649119.1 silverDB:cEP02116 YP_002649120.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002649121.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002649122.1 silverDB:cEP02119 YP_002649123.1 silverDB:cEP02120 YP_002649124.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_002649125.1 silverDB:cEP02122 YP_002649126.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_002649127.1 silverDB:cEP02124 YP_002649128.1 silverDB:cEP02125 YP_002649129.1 silverDB:cEP02126 YP_002649130.1 silverDB:cEP02127 YP_002649131.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_002649132.1 silverDB:cEP02129 YP_002649133.1 silverDB:cEP02130 YP_002649134.1 silverDB:cEP02131 YP_002649135.1 silverDB:cEP02132 YP_002649136.1 silverDB:cEP02133 YP_002649137.1 silverDB:cEP02134 YP_002649138.1 silverDB:cEP02135 YP_002649139.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002649140.1 silverDB:cEP02137 YP_002649141.1 silverDB:cEP02138 YP_002649142.1 silverDB:cEP02139 YP_002649143.1 silverDB:cEP02140 YP_002649144.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002649145.1 silverDB:cEP02142 YP_002649146.1 silverDB:cEP02143 YP_002649147.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002649148.1 silverDB:cEP02145 YP_002649149.1 silverDB:cEP02146 YP_002649150.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002649151.1 carries the fatty acid chain in fatty acid biosynthesis YP_002649152.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002649153.1 silverDB:cEP02150 YP_002649154.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002649155.1 silverDB:cEP02152 YP_002649156.1 silverDB:cEP02153 YP_002649157.1 silverDB:cEP02154 YP_002649158.1 silverDB:cEP02155 YP_002649159.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_002649160.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_002649161.1 silverDB:cEP02158 YP_002649162.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002649163.1 flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002649164.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_002649165.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_002649166.1 silverDB:cEP02163 YP_002649167.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_002649168.1 the hook connects flagellar basal body to the flagellar filament YP_002649169.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_002649170.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002649171.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_002649172.1 silverDB:cEP02169 YP_002649173.1 silverDB:cEP02170 YP_002649174.1 silverDB:cEP02171 YP_002649175.1 silverDB:cEP02172 YP_002649176.1 silverDB:cEP02173 YP_002649177.1 silverDB:cEP02174 YP_002649178.1 silverDB:cEP02175 YP_002649179.1 silverDB:cEP02176 YP_002649180.1 cofactor involved in the reduction of disulfides YP_002649181.1 silverDB:cEP02178 YP_002649182.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002649183.1 silverDB:cEP02180 YP_002649184.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_002649185.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_002649186.1 silverDB:cEP02183 YP_002649187.1 silverDB:cEP02184 YP_002649188.1 silverDB:cEP02185 YP_002649189.1 silverDB:cEP02186 YP_002649190.1 silverDB:cEP02187 YP_002649191.1 silverDB:cEP02188 YP_002649192.1 silverDB:cEP02189 YP_002649193.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_002649194.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_002649195.1 required for the transfer of succinyl residues to the glucan backbone YP_002649196.1 silverDB:cEP02193 YP_002649197.1 silverDB:cEP02194 YP_002649198.1 silverDB:cEP02195 YP_002649199.1 silverDB:cEP02196 YP_002649200.1 silverDB:cEP02197 YP_002649201.1 silverDB:cEP02198 YP_002649202.1 silverDB:cEP02199 YP_002649203.1 silverDB:cEP02200 YP_002649204.1 silverDB:cEP02201 YP_002649205.1 silverDB:cEP02202 YP_002649206.1 silverDB:cEP02203 YP_002649207.1 silverDB:cEP02204 YP_002649208.1 silverDB:cEP02205 YP_002649209.1 silverDB:cEP02206 YP_002649210.1 silverDB:cEP02208 YP_002649211.1 silverDB:cEP02209 YP_002649212.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002649213.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002649214.1 silverDB:cEP02212 YP_002649215.1 silverDB:cEP02213 YP_002649216.1 silverDB:cEP02214 YP_002649217.1 silverDB:cEP02215 YP_002649218.1 silverDB:cEP02216 YP_002649219.1 silverDB:cEP02217 YP_002649220.1 silverDB:cEP02218 YP_002649221.1 silverDB:cEP02219 YP_002649222.1 silverDB:cEP02220 YP_002649223.1 silverDB:cEP02221 YP_002649224.1 silverDB:cEP02222 YP_002649225.1 silverDB:cEP02223 YP_002649226.1 silverDB:cEP02224 YP_002649227.1 silverDB:cEP02225 YP_002649228.1 silverDB:cEP02226 YP_002649229.1 silverDB:cEP02227 YP_002649230.1 silverDB:cEP02228 YP_002649231.1 silverDB:cEP02229 YP_002649232.1 silverDB:cEP02230 YP_002649233.1 silverDB:cEP02231 YP_002649234.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002649235.1 silverDB:cEP02233 YP_002649236.1 silverDB:cEP02234 YP_002649237.1 silverDB:cEP02235 YP_002649238.1 silverDB:cEP02236 YP_002649239.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_002649240.1 silverDB:cEP02238 YP_002649241.1 silverDB:cEP02239 YP_002649242.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_002649243.1 silverDB:cEP02241 YP_002649244.1 silverDB:cEP02242 YP_002649245.1 silverDB:cEP02243 YP_002649246.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002649247.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002649248.1 silverDB:cEP02246 YP_002649249.1 silverDB:cEP02247 YP_002649250.1 silverDB:cEP02248 YP_002649251.1 silverDB:cEP02249 YP_002649252.1 silverDB:cEP02250 YP_002649253.1 catalyzes the release of sulfite from alkanesulfonates YP_002649254.1 silverDB:cEP02252 YP_002649255.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_002649256.1 silverDB:cEP02254 YP_002649257.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002649258.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002649259.1 silverDB:cEP02257 YP_002649260.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002649261.1 silverDB:cEP02259 YP_002649262.1 silverDB:cEP02260 YP_002649263.1 silverDB:cEP02261 YP_002649264.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002649265.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002649266.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002649267.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002649268.1 silverDB:cEP02266 YP_002649269.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002649270.1 silverDB:cEP02268 YP_002649271.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_002649272.1 involved in the transport of lipid A across the inner membrane YP_002649273.1 silverDB:cEP02271 YP_002649274.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002649275.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002649276.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002649277.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002649278.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002649279.1 silverDB:cEP02277 YP_002649280.1 silverDB:cEP02279 YP_002649281.1 silverDB:cEP02280 YP_002649282.1 silverDB:cEP02281 YP_002649283.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002649284.1 silverDB:cEP02284 YP_002649285.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002649286.1 silverDB:cEP02286 YP_002649287.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_002649288.1 silverDB:cEP02288 YP_002649289.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002649290.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002649291.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_002649292.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_002649293.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002649294.1 silverDB:cEP02295 YP_002649295.1 silverDB:cEP02296 YP_002649296.1 catalyzes the formation of acetate from pyruvate YP_002649297.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_002649298.1 silverDB:cEP02299 YP_002649299.1 silverDB:cEP02300 YP_002649300.1 silverDB:cEP02301 YP_002649301.1 With ArtMQJI transports arginine across the inner membrane YP_002649302.1 silverDB:cEP02303 YP_002649303.1 with ArtPMJI transports arginine across the inner membrane YP_002649304.1 with ArtPQJI acts to transport arginine across the inner membrane YP_002649305.1 silverDB:cEP02306 YP_002649306.1 silverDB:cEP02307 YP_002649307.1 silverDB:cEP02308 YP_002649308.1 silverDB:cEP02309 YP_002649309.1 part of the PotFGHI ATP-dependent putrescine transporter YP_002649310.1 silverDB:cEP02311 YP_002649311.1 silverDB:cEP02312 YP_002649312.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_002649313.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_002649314.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_002649315.1 silverDB:cEP02316 YP_002649316.1 silverDB:cEP02317 YP_002649317.1 silverDB:cEP02318 YP_002649318.1 silverDB:cEP02319 YP_002649319.1 silverDB:cEP02320 YP_002649320.1 silverDB:cEP02321 YP_002649321.1 silverDB:cEP02322 YP_002649322.1 silverDB:cEP02323 YP_002649323.1 silverDB:cEP02324 YP_002649324.1 silverDB:cEP02325 YP_002649325.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_002649326.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_002649327.1 silverDB:cEP02328 YP_002649328.1 silverDB:cEP02329 YP_002649329.1 silverDB:cEP02330 YP_002649330.1 silverDB:cEP02331 YP_002649331.1 silverDB:cEP02332 YP_002649332.1 silverDB:cEP02333 YP_002649333.1 silverDB:cEP02334 YP_002649334.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_002649335.1 silverDB:cEP02336 YP_002649336.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_002649337.1 silverDB:cEP02338 YP_002649338.1 periplasmic-binding component of ABC transporters YP_002649339.1 permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002649340.1 ATP-binding component of ABC transporters YP_002649341.1 silverDB:cEP02342 YP_002649342.1 silverDB:cEP02343 YP_002649343.1 silverDB:cEP02345 YP_002649344.1 silverDB:cEP02346 YP_002649345.1 silverDB:cEP02347 YP_002649346.1 silverDB:cEP02348 YP_002649347.1 silverDB:cEP02349 YP_002649348.1 silverDB:cEP02350 YP_002649349.1 silverDB:cEP02351 YP_002649350.1 silverDB:cEP02352 YP_002649351.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002649352.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_002649353.1 silverDB:cEP02355 YP_002649354.1 silverDB:cEP02356 YP_002649355.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002649356.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002649357.1 silverDB:cEP02359 YP_002649358.1 silverDB:cEP02360 YP_002649359.1 helicase involved in DNA repair and perhaps also replication YP_002649360.1 silverDB:cEP02362 YP_002649361.1 silverDB:cEP02363 YP_002649362.1 silverDB:cEP02364 YP_002649363.1 silverDB:cEP02365 YP_002649364.1 silverDB:cEP02366 YP_002649365.1 silverDB:cEP02367 YP_002649366.1 silverDB:cEP02368 YP_002649367.1 silverDB:cEP02369 YP_002649368.1 silverDB:cEP02370 YP_002649369.1 silverDB:cEP02371 YP_002649370.1 silverDB:cEP02372 YP_002649371.1 silverDB:cEP02373 YP_002649372.1 silverDB:cEP02374 YP_002649373.1 silverDB:cEP02375 YP_002649374.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_002649375.1 silverDB:cEP02377 YP_002649376.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_002649377.1 silverDB:cEP02379 YP_002649378.1 silverDB:cEP02380 YP_002649379.1 silverDB:cEP02381 YP_002649380.1 silverDB:cEP02382 YP_002649381.1 silverDB:cEP02383 YP_002649382.1 this helicase is not essential cell growth YP_002649383.1 silverDB:cEP02385 YP_002649384.1 silverDB:cEP02386 YP_002649385.1 silverDB:cEP02387 YP_002649386.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002649387.1 silverDB:cEP02389 YP_002649388.1 silverDB:cEP02390 YP_002649389.1 silverDB:cEP02391 YP_002649390.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002649391.1 silverDB:cEP02393 YP_002649392.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002649393.1 silverDB:cEP02395 YP_002649394.1 silverDB:cEP02396 YP_002649395.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002649396.1 silverDB:cEP02398 YP_002649397.1 silverDB:cEP02399 YP_002649398.1 silverDB:cEP02400 YP_002649399.1 silverDB:cEP02401 YP_002649400.1 silverDB:cEP02402 YP_002649401.1 YbhB; rat and human kinase inhibitory proteins YP_002649402.1 silverDB:cEP02404 YP_002649403.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_002649404.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002649405.1 silverDB:cEP02407 YP_002649406.1 with ModCB is involved in the high-affinity transport of molybdate YP_002649407.1 silverDB:cEP02409 YP_002649408.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_002649409.1 silverDB:cEP02412 YP_002649410.1 silverDB:cEP02413 YP_002649411.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_002649412.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_002649413.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002649414.1 silverDB:cEP02417 YP_002649415.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002649416.1 silverDB:cEP02419 YP_002649417.1 silverDB:cEP02420 YP_002649418.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002649419.1 silverDB:cEP02422 YP_002649420.1 involved in zinc efflux across the cytoplasmic membrane YP_002649421.1 silverDB:cEP02424 YP_002649422.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002649423.1 silverDB:cEP02426 YP_002649424.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_002649425.1 silverDB:cEP02430 YP_002649426.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002649427.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_002649428.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002649429.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002649430.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_002649431.1 silverDB:cEP02436 YP_002649432.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002649433.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002649434.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002649435.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are fumarate reductase YP_002649436.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002649437.1 silverDB:cEP02442 YP_002649438.1 silverDB:cEP02443 YP_002649439.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_002649440.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_002649441.1 silverDB:cEP02446 YP_002649442.1 silverDB:cEP02447 YP_002649443.1 silverDB:cEP02448 YP_002649444.1 silverDB:cEP02449 YP_002649445.1 silverDB:cEP02450 YP_002649446.1 silverDB:cEP02451 YP_002649447.1 silverDB:cEP02452 YP_002649448.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_002649449.1 silverDB:cEP02454 YP_002649450.1 silverDB:cEP02455 YP_002649451.1 silverDB:cEP02456 YP_002649452.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002649453.1 negative modulator of the initiation of chromosome replication YP_002649454.1 silverDB:cEP02459 YP_002649455.1 silverDB:cEP02460 YP_002649456.1 silverDB:cEP02461 YP_002649457.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_002649458.1 silverDB:cEP02463 YP_002649459.1 silverDB:cEP02464 YP_002649460.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002649461.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002649462.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002649463.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_002649464.1 silverDB:cEP02469 YP_002649465.1 silverDB:cEP02470 YP_002649466.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_002649467.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_002649468.1 silverDB:cEP02473 YP_002649469.1 silverDB:cEP02474 YP_002649470.1 silverDB:cEP02475 YP_002649471.1 silverDB:cEP02476 YP_002649472.1 transfers the fatty acyl group on membrane lipoproteins YP_002649473.1 silverDB:cEP02478 YP_002649474.1 silverDB:cEP02479 YP_002649475.1 silverDB:cEP02480 YP_002649476.1 silverDB:cEP02481 YP_002649477.1 silverDB:cEP02482 YP_002649478.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002649479.1 silverDB:cEP02484 YP_002649480.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002649481.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002649482.1 silverDB:cEP02487 YP_002649483.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002649484.1 silverDB:cEP02489 YP_002649485.1 silverDB:cEP02490 YP_002649486.1 silverDB:cEP02491 YP_002649487.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_002649488.1 silverDB:cEP02493 YP_002649489.1 silverDB:cEP02494 YP_002649490.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002649491.1 TatE; TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; a protein import system in thylakoid membranes YP_002649492.1 silverDB:cEP02497 YP_002649493.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_002649494.1 catalyzes the transfer of palmitate to lipid A YP_002649495.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_002649496.1 silverDB:cEP02501 YP_002649497.1 silverDB:cEP02502 YP_002649498.1 silverDB:cEP02503 YP_002649499.1 silverDB:cEP02504 YP_002649500.1 silverDB:cEP02505 YP_002649501.1 silverDB:cEP02506 YP_002649502.1 silverDB:cEP02507 YP_002649503.1 silverDB:cEP02508 YP_002649504.1 silverDB:cEP02509 YP_002649505.1 silverDB:cEP02510 YP_002649506.1 silverDB:cEP02511 YP_002649507.1 silverDB:cEP02512 YP_002649508.1 silverDB:cEP02513 YP_002649509.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_002649510.1 silverDB:cEP02516 YP_002649511.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_002649512.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_002649513.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_002649514.1 silverDB:cEP02520 YP_002649515.1 silverDB:cEP02521 YP_002649516.1 silverDB:cEP02524 YP_002649517.1 silverDB:cEP02525 YP_002649518.1 silverDB:cEP02526 YP_002649519.1 silverDB:cEP02527 YP_002649520.1 silverDB:cEP02528 YP_002649521.1 silverDB:cEP02529 YP_002649522.1 silverDB:cEP02530 YP_002649523.1 silverDB:cEP02531 YP_002649524.1 silverDB:cEP02532 YP_002649525.1 silverDB:cEP02533 YP_002649526.1 silverDB:cEP02534 YP_002649527.1 silverDB:cEP02535 YP_002649528.1 silverDB:cEP02536 YP_002649529.1 silverDB:cEP02539 YP_002649530.1 silverDB:cEP02540 YP_002649531.1 silverDB:cEP02541 YP_002649532.1 silverDB:cEP02542 YP_002649533.1 silverDB:cEP02543 YP_002649534.1 silverDB:cEP02544 YP_002649535.1 silverDB:cEP02545 YP_002649536.1 silverDB:cEP02546 YP_002649537.1 silverDB:cEP02547 YP_002649538.1 silverDB:cEP02548 YP_002649539.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002649540.1 silverDB:cEP02550 YP_002649541.1 zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002649542.1 silverDB:cEP02552 YP_002649543.1 silverDB:cEP02553 YP_002649544.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_002649545.1 silverDB:cEP02555 YP_002649546.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002649547.1 silverDB:cEP02557 YP_002649548.1 silverDB:cEP02558 YP_002649549.1 silverDB:cEP02559 YP_002649550.1 silverDB:cEP02560 YP_002649551.1 silverDB:cEP02561 YP_002649552.1 silverDB:cEP02562 YP_002649553.1 silverDB:cEP02563 YP_002649554.1 silverDB:cEP02564 YP_002649555.1 silverDB:cEP02565 YP_002649556.1 silverDB:cEP02566 YP_002649557.1 silverDB:cEP02567 YP_002649558.1 silverDB:cEP02568 YP_002649559.1 silverDB:cEP02569 YP_002649560.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_002649561.1 silverDB:cEP02571 YP_002649562.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_002649563.1 silverDB:cEP02573 YP_002649564.1 silverDB:cEP02574 YP_002649565.1 silverDB:cEP02575 YP_002649566.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002649567.1 silverDB:cEP02577 YP_002649568.1 silverDB:cEP02578 YP_002649569.1 silverDB:cEP02579 YP_002649570.1 silverDB:cEP02580 YP_002649571.1 silverDB:cEP02581 YP_002649572.1 silverDB:cEP02582 YP_002649573.1 silverDB:cEP02583 YP_002649574.1 silverDB:cEP02584 YP_002649575.1 molecular chaperone YP_002649576.1 silverDB:cEP02586 YP_002649577.1 silverDB:cEP02587 YP_002649578.1 silverDB:cEP02588 YP_002649579.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002649580.1 silverDB:cEP02590 YP_002649581.1 silverDB:cEP02591 YP_002649582.1 silverDB:cEP02592 YP_002649583.1 silverDB:cEP02593 YP_002649584.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_002649585.1 silverDB:cEP02595 YP_002649586.1 silverDB:cEP02596 YP_002649587.1 silverDB:cEP02597 YP_002649588.1 silverDB:cEP02598 YP_002649589.1 silverDB:cEP02599 YP_002649590.1 silverDB:cEP02600 YP_002649591.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_002649592.1 silverDB:cEP02602 YP_002649593.1 silverDB:cEP02603 YP_002649594.1 silverDB:cEP02604 YP_002649595.1 silverDB:cEP02605 YP_002649596.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_002649597.1 silverDB:cEP02607 YP_002649598.1 silverDB:cEP02608 YP_002649599.1 silverDB:cEP02609 YP_002649600.1 silverDB:cEP02610 YP_002649601.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_002649602.1 silverDB:cEP02612 YP_002649603.1 silverDB:cEP02613 YP_002649604.1 silverDB:cEP02614 YP_002649605.1 silverDB:cEP02615 YP_002649606.1 silverDB:cEP02616 YP_002649607.1 binds and unfolds substrates as part of the ClpXP protease YP_002649608.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002649609.1 binds and unfolds substrates as part of the ClpXP protease YP_002649610.1 silverDB:cEP02620 YP_002649611.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002649612.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_002649613.1 silverDB:cEP02623 YP_002649614.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_002649615.1 silverDB:cEP02625 YP_002649616.1 silverDB:cEP02626 YP_002649617.1 silverDB:cEP02627 YP_002649618.1 silverDB:cEP02628 YP_002649619.1 silverDB:cEP02629 YP_002649620.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002649621.1 silverDB:cEP02631 YP_002649622.1 silverDB:cEP02633 YP_002649623.1 silverDB:cEP02634 YP_002649624.1 silverDB:cEP02635 YP_002649625.1 silverDB:cEP02636 YP_002649626.1 silverDB:cEP02637 YP_002649627.1 silverDB:cEP02638 YP_002649628.1 silverDB:cEP02639 YP_002649629.1 Required for the synthesis of the thiazole moiety YP_002649630.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002649631.1 silverDB:cEP02642 YP_002649632.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002649633.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002649634.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002649635.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002649636.1 silverDB:cEP02647 YP_002649637.1 silverDB:cEP02648 YP_002649638.1 silverDB:cEP02649 YP_002649639.1 silverDB:cEP02650 YP_002649640.1 silverDB:cEP02651 YP_002649641.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002649642.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002649643.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002649644.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002649645.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002649646.1 silverDB:cEP02657 YP_002649647.1 silverDB:cEP02658 YP_002649648.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_002649649.1 silverDB:cEP02660 YP_002649650.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_002649651.1 silverDB:cEP02662 YP_002649652.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002649653.1 silverDB:cEP02664 YP_002649654.1 silverDB:cEP02665 YP_002649655.1 silverDB:cEP02666 YP_002649656.1 silverDB:cEP02667 YP_002649657.1 silverDB:cEP02668 YP_002649658.1 silverDB:cEP02669 YP_002649659.1 silverDB:cEP02670 YP_002649660.1 silverDB:cEP02672 YP_002649661.1 silverDB:cEP02673 YP_002649662.1 silverDB:cEP02674 YP_002649663.1 silverDB:cEP02675 YP_002649664.1 Required for efficient pilin antigenic variation YP_002649665.1 silverDB:cEP02677 YP_002649666.1 silverDB:cEP02678 YP_002649667.1 silverDB:cEP02679 YP_002649668.1 silverDB:cEP02680 YP_002649669.1 silverDB:cEP02681 YP_002649670.1 silverDB:cEP02682 YP_002649671.1 silverDB:cEP02683 YP_002649672.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002649673.1 silverDB:cEP02685 YP_002649674.1 silverDB:cEP02686 YP_002649675.1 silverDB:cEP02691 YP_002649676.1 silverDB:cEP02692 YP_002649677.1 silverDB:cEP02693 YP_002649678.1 silverDB:cEP02694 YP_002649679.1 silverDB:cEP02695 YP_002649680.1 silverDB:cEP02696 YP_002649681.1 silverDB:cEP02697 YP_002649682.1 silverDB:cEP02698 YP_002649683.1 silverDB:cEP02699 YP_002649684.1 silverDB:cEP02700 YP_002649685.1 silverDB:cEP02701 YP_002649686.1 silverDB:cEP02702 YP_002649687.1 silverDB:cEP02703 YP_002649688.1 silverDB:cEP02704 YP_002649689.1 silverDB:cEP02705 YP_002649690.1 silverDB:cEP02706 YP_002649691.1 silverDB:cEP02707 YP_002649692.1 silverDB:cEP02708 YP_002649693.1 silverDB:cEP02709 YP_002649694.1 silverDB:cEP02710 YP_002649695.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002649696.1 silverDB:cEP02712 YP_002649697.1 silverDB:cEP02713 YP_002649698.1 silverDB:cEP02714 YP_002649699.1 silverDB:cEP02715 YP_002649700.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002649701.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002649702.1 silverDB:cEP02718 YP_002649703.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_002649704.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002649705.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_002649706.1 silverDB:cEP02722 YP_002649707.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002649708.1 silverDB:cEP02724 YP_002649709.1 silverDB:cEP02725 YP_002649710.1 silverDB:cEP02726 YP_002649711.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_002649712.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_002649713.1 silverDB:cEP02729 YP_002649714.1 silverDB:cEP02730 YP_002649715.1 silverDB:cEP02731 YP_002649716.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_002649717.1 silverDB:cEP02733 YP_002649718.1 silverDB:cEP02734 YP_002649719.1 silverDB:cEP02735 YP_002649720.1 catalyzes the transfer of an amino moiety YP_002649721.1 silverDB:cEP02737 YP_002649722.1 silverDB:cEP02738 YP_002649723.1 silverDB:cEP02739 YP_002649724.1 silverDB:cEP02740 YP_002649725.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002649726.1 silverDB:cEP02742 YP_002649727.1 silverDB:cEP02743 YP_002649728.1 silverDB:cEP02744 YP_002649729.1 silverDB:cEP02745 YP_002649730.1 silverDB:cEP02746 YP_002649731.1 silverDB:cEP02747 YP_002649732.1 silverDB:cEP02748 YP_002649733.1 silverDB:cEP02749 YP_002649734.1 silverDB:cEP02750 YP_002649735.1 silverDB:cEP02751 YP_002649736.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002649737.1 silverDB:cEP02753 YP_002649738.1 silverDB:cEP02754 YP_002649739.1 silverDB:cEP02755 YP_002649740.1 silverDB:cEP02756 YP_002649741.1 silverDB:cEP02757 YP_002649742.1 silverDB:cEP02758 YP_002649743.1 3'-5' exonuclease of DNA polymerase III YP_002649744.1 silverDB:cEP02762 YP_002649745.1 silverDB:cEP02763 YP_002649746.1 silverDB:cEP02764 YP_002649747.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_002649748.1 silverDB:cEP02766 YP_002649749.1 silverDB:cEP02767 YP_002649750.1 silverDB:cEP02768 YP_002649751.1 silverDB:cEP02769 YP_002649752.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_002649753.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_002649754.1 silverDB:cEP02772 YP_002649755.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002649756.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002649757.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002649758.1 silverDB:cEP02777 YP_002649759.1 silverDB:cEP02778 YP_002649760.1 silverDB:cEP02779 YP_002649761.1 silverDB:cEP02780 YP_002649762.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002649763.1 silverDB:cEP02782 YP_002649764.1 Essential for efficient processing of 16S rRNA YP_002649765.1 silverDB:cEP02784 YP_002649766.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_002649767.1 silverDB:cEP02786 YP_002649768.1 silverDB:cEP02787 YP_002649769.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002649770.1 silverDB:cEP02789 YP_002649771.1 silverDB:cEP02790 YP_002649772.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_002649773.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002649774.1 silverDB:cEP02793 YP_002649775.1 silverDB:cEP02794 YP_002649776.1 silverDB:cEP02795 YP_002649777.1 silverDB:cEP02796 YP_002649778.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_002649779.1 silverDB:cEP02798 YP_002649780.1 silverDB:cEP02799 YP_002649781.1 silverDB:cEP02800 YP_002649782.1 silverDB:cEP02801 YP_002649783.1 silverDB:cEP02803 YP_002649784.1 silverDB:cEP02804 YP_002649785.1 silverDB:cEP02805 YP_002649786.1 silverDB:cEP02806 YP_002649787.1 silverDB:cEP02807 YP_002649788.1 silverDB:cEP02808 YP_002649789.1 silverDB:cEP02809 YP_002649790.1 silverDB:cEP02810 YP_002649791.1 silverDB:cEP02811 YP_002649792.1 silverDB:cEP02812 YP_002649793.1 silverDB:cEP02813 YP_002649794.1 silverDB:cEP02814 YP_002649795.1 This protein performs the mismatch recognition step during the DNA repair process YP_002649796.1 silverDB:cEP02816 YP_002649797.1 silverDB:cEP02817 YP_002649798.1 outer membrane lipoprotein involved in stationary-phase cell survival; LppB virulence determinant from Haemophilus somnus YP_002649799.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002649800.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002649801.1 catalyzes the modification of U13 in tRNA(Glu) YP_002649802.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002649803.1 silverDB:cEP02823 YP_002649804.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002649805.1 silverDB:cEP02825 YP_002649806.1 silverDB:cEP02826 YP_002649807.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002649808.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002649809.1 silverDB:cEP02829 YP_002649810.1 silverDB:cEP02830 YP_002649811.1 silverDB:cEP02831 YP_002649812.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002649813.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_002649814.1 silverDB:cEP02834 YP_002649815.1 silverDB:cEP02835 YP_002649816.1 silverDB:cEP02836 YP_002649817.1 silverDB:cEP02837 YP_002649818.1 silverDB:cEP02838 YP_002649819.1 silverDB:cEP02839 YP_002649820.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002649821.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002649822.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_002649823.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_002649824.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002649825.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002649826.1 silverDB:cEP02846 YP_002649827.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002649828.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002649829.1 silverDB:cEP02849 YP_002649830.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002649831.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002649832.1 silverDB:cEP02852 YP_002649833.1 silverDB:cEP02853 YP_002649834.1 silverDB:cEP02854 YP_002649835.1 silverDB:cEP02855 YP_002649836.1 glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002649837.1 silverDB:cEP02857 YP_002649838.1 silverDB:cEP02858 YP_002649839.1 silverDB:cEP02859 YP_002649840.1 silverDB:cEP02860 YP_002649841.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002649842.1 silverDB:cEP02862 YP_002649843.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002649844.1 silverDB:cEP02864 YP_002649845.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002649846.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002649847.1 silverDB:cEP02867 YP_002649848.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002649849.1 silverDB:cEP02869 YP_002649850.1 silverDB:cEP02870 YP_002649851.1 silverDB:cEP02871 YP_002649852.1 silverDB:cEP02872 YP_002649853.1 silverDB:cEP02873 YP_002649854.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002649855.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002649856.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002649857.1 hydrolyzes diadenosine polyphosphate YP_002649858.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002649859.1 silverDB:cEP02879 YP_002649860.1 silverDB:cEP02880 YP_002649861.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_002649862.1 silverDB:cEP02882 YP_002649863.1 transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_002649864.1 silverDB:cEP02884 YP_002649865.1 silverDB:cEP02885 YP_002649866.1 silverDB:cEP02886 YP_002649867.1 silverDB:cEP02887 YP_002649868.1 silverDB:cEP02888 YP_002649869.1 silverDB:cEP02889 YP_002649870.1 silverDB:cEP02890 YP_002649871.1 silverDB:cEP02891 YP_002649872.1 silverDB:cEP02892 YP_002649873.1 silverDB:cEP02893 YP_002649874.1 silverDB:cEP02894 YP_002649875.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_002649876.1 silverDB:cEP02896 YP_002649877.1 silverDB:cEP02897 YP_002649878.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002649879.1 silverDB:cEP02899 YP_002649880.1 silverDB:cEP02900 YP_002649881.1 silverDB:cEP02901 YP_002649882.1 silverDB:cEP02902 YP_002649883.1 silverDB:cEP02903 YP_002649884.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_002649885.1 silverDB:cEP02905 YP_002649886.1 silverDB:cEP02906 YP_002649887.1 silverDB:cEP02907 YP_002649888.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002649889.1 silverDB:cEP02909 YP_002649890.1 silverDB:cEP02910 YP_002649891.1 silverDB:cEP02911 YP_002649892.1 silverDB:cEP02912 YP_002649893.1 silverDB:cEP02913 YP_002649894.1 silverDB:cEP02914 YP_002649895.1 silverDB:cEP02915 YP_002649896.1 silverDB:cEP02916 YP_002649897.1 silverDB:cEP02917 YP_002649898.1 silverDB:cEP02918 YP_002649899.1 silverDB:cEP02919 YP_002649900.1 silverDB:cEP02920 YP_002649901.1 controls transcription of galETKM YP_002649902.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002649903.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002649904.1 silverDB:cEP02924 YP_002649905.1 silverDB:cEP02925 YP_002649906.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002649907.1 silverDB:cEP02927 YP_002649908.1 silverDB:cEP02928 YP_002649909.1 5'-3' single-stranded-DNA-specific exonuclease YP_002649910.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_002649911.1 silverDB:cEP02931 YP_002649912.1 silverDB:cEP02932 YP_002649913.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_002649914.1 silverDB:cEP02934 YP_002649915.1 silverDB:cEP02935 YP_002649916.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_002649917.1 silverDB:cEP02937 YP_002649918.1 silverDB:cEP02938 YP_002649919.1 silverDB:cEP02939 YP_002649920.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002649921.1 silverDB:cEP02941 YP_002649922.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002649923.1 silverDB:cEP02943 YP_002649924.1 silverDB:cEP02944 YP_002649925.1 silverDB:cEP02945 YP_002649926.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_002649927.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_002649928.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002649929.1 silverDB:cEP02949 YP_002649930.1 silverDB:cEP02950 YP_002649931.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002649932.1 silverDB:cEP02952 YP_002649933.1 silverDB:cEP02953 YP_002649934.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002649935.1 silverDB:cEP02955 YP_002649936.1 silverDB:cEP02956 YP_002649937.1 silverDB:cEP02957 YP_002649938.1 silverDB:cEP02958 YP_002649939.1 silverDB:cEP02959 YP_002649940.1 silverDB:cEP02960 YP_002649941.1 silverDB:cEP02961 YP_002649942.1 silverDB:cEP02962 YP_002649943.1 silverDB:cEP02963 YP_002649944.1 silverDB:cEP02964 YP_002649945.1 silverDB:cEP02965 YP_002649946.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002649947.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002649948.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002649949.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002649950.1 silverDB:cEP02970 YP_002649951.1 silverDB:cEP02971 YP_002649952.1 silverDB:cEP02972 YP_002649953.1 catalyzes the formation of putrescine from agmatine YP_002649954.1 silverDB:cEP02974 YP_002649955.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002649956.1 silverDB:cEP02976 YP_002649957.1 silverDB:cEP02977 YP_002649958.1 silverDB:cEP02978 YP_002649959.1 silverDB:cEP02979 YP_002649960.1 silverDB:cEP02980 YP_002649961.1 silverDB:cEP02981 YP_002649962.1 silverDB:cEP02982 YP_002649963.1 silverDB:cEP02983 YP_002649964.1 silverDB:cEP02984 YP_002649965.1 silverDB:cEP02985 YP_002649966.1 silverDB:cEP02986 YP_002649967.1 silverDB:cEP02987 YP_002649968.1 silverDB:cEP02988 YP_002649969.1 silverDB:cEP02989 YP_002649970.1 silverDB:cEP02990 YP_002649971.1 silverDB:cEP02991 YP_002649972.1 silverDB:cEP02992 YP_002649973.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002649974.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002649975.1 silverDB:cEP02995 YP_002649976.1 silverDB:cEP02996 YP_002649977.1 silverDB:cEP02997 YP_002649978.1 silverDB:cEP02998 YP_002649979.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002649980.1 silverDB:cEP03000 YP_002649981.1 silverDB:cEP03001 YP_002649982.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_002649983.1 silverDB:cEP03003 YP_002649984.1 silverDB:cEP03004 YP_002649985.1 silverDB:cEP03005 YP_002649986.1 silverDB:cEP03006 YP_002649987.1 silverDB:cEP03007 YP_002649988.1 silverDB:cEP03008 YP_002649989.1 silverDB:cEP03009 YP_002649990.1 silverDB:cEP03010 YP_002649991.1 silverDB:cEP03011 YP_002649992.1 silverDB:cEP03012 YP_002649993.1 silverDB:cEP03013 YP_002649994.1 silverDB:cEP03014 YP_002649995.1 silverDB:cEP03015 YP_002649996.1 silverDB:cEP03016 YP_002649997.1 silverDB:cEP03017 YP_002649998.1 silverDB:cEP03018 YP_002649999.1 silverDB:cEP03019 YP_002650000.1 silverDB:cEP03020 YP_002650001.1 silverDB:cEP03021 YP_002650002.1 silverDB:cEP03022 YP_002650003.1 silverDB:cEP03023 YP_002650004.1 silverDB:cEP03024 YP_002650005.1 silverDB:cEP03025 YP_002650006.1 silverDB:cEP03026 YP_002650007.1 silverDB:cEP03027 YP_002650008.1 silverDB:cEP03028 YP_002650009.1 silverDB:cEP03029 YP_002650010.1 silverDB:cEP03030 YP_002650011.1 silverDB:cEP03031 YP_002650012.1 silverDB:cEP03032 YP_002650013.1 silverDB:cEP03033 YP_002650014.1 silverDB:cEP03034 YP_002650015.1 silverDB:cEP03035 YP_002650016.1 silverDB:cEP03036 YP_002650017.1 silverDB:cEP03037 YP_002650018.1 silverDB:cEP03038 YP_002650019.1 silverDB:cEP03039 YP_002650020.1 silverDB:cEP03040 YP_002650021.1 silverDB:cEP03041 YP_002650022.1 silverDB:cEP03042 YP_002650023.1 silverDB:cEP03043 YP_002650024.1 silverDB:cEP03044 YP_002650025.1 silverDB:cEP03045 YP_002650026.1 silverDB:cEP03046 YP_002650027.1 silverDB:cEP03047 YP_002650028.1 silverDB:cEP03048 YP_002650029.1 silverDB:cEP03049 YP_002650030.1 silverDB:cEP03050 YP_002650031.1 silverDB:cEP03051 YP_002650032.1 silverDB:cEP03052 YP_002650033.1 silverDB:cEP03053 YP_002650034.1 silverDB:cEP03054 YP_002650035.1 silverDB:cEP03055 YP_002650036.1 silverDB:cEP03056 YP_002650037.1 silverDB:cEP03057 YP_002650038.1 silverDB:cEP03058 YP_002650039.1 silverDB:cEP03059 YP_002650040.1 silverDB:cEP03060 YP_002650041.1 silverDB:cEP03061 YP_002650042.1 silverDB:cEP03062 YP_002650043.1 silverDB:cEP03063 YP_002650044.1 silverDB:cEP03064 YP_002650045.1 silverDB:cEP03065 YP_002650046.1 silverDB:cEP03066 YP_002650047.1 silverDB:cEP03067 YP_002650048.1 silverDB:cEP03068 YP_002650049.1 silverDB:cEP03069 YP_002650050.1 silverDB:cEP03070 YP_002650051.1 silverDB:cEP03071 YP_002650052.1 silverDB:cEP03072 YP_002650053.1 silverDB:cEP03073 YP_002650054.1 silverDB:cEP03074 YP_002650055.1 silverDB:cEP03075 YP_002650056.1 silverDB:cEP03076 YP_002650057.1 silverDB:cEP03077 YP_002650058.1 silverDB:cEP03078 YP_002650059.1 silverDB:cEP03079 YP_002650060.1 silverDB:cEP03080 YP_002650061.1 silverDB:cEP03081 YP_002650062.1 silverDB:cEP03082 YP_002650063.1 silverDB:cEP03083 YP_002650064.1 silverDB:cEP03084 YP_002650065.1 silverDB:cEP03085 YP_002650066.1 silverDB:cEP03086 YP_002650067.1 silverDB:cEP03087 YP_002650068.1 silverDB:cEP03088 YP_002650069.1 silverDB:cEP03089 YP_002650070.1 silverDB:cEP03090 YP_002650071.1 silverDB:cEP03091 YP_002650072.1 silverDB:cEP03092 YP_002650073.1 silverDB:cEP03093 YP_002650074.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_002650075.1 silverDB:cEP03095 YP_002650076.1 silverDB:cEP03096 YP_002650077.1 silverDB:cEP03097 YP_002650078.1 silverDB:cEP03098 YP_002650079.1 silverDB:cEP03099 YP_002650080.1 silverDB:cEP03100 YP_002650081.1 silverDB:cEP03101 YP_002650082.1 silverDB:cEP03102 YP_002650083.1 silverDB:cEP03103 YP_002650084.1 silverDB:cEP03104 YP_002650085.1 inactivates vertebrate C-type lysozyme YP_002650086.1 silverDB:cEP03106 YP_002650087.1 silverDB:cEP03107 YP_002650088.1 silverDB:cEP03108 YP_002650089.1 silverDB:cEP03109 YP_002650090.1 silverDB:cEP03110 YP_002650091.1 silverDB:cEP03111 YP_002650092.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_002650093.1 silverDB:cEP03113 YP_002650094.1 silverDB:cEP03114 YP_002650095.1 silverDB:cEP03115 YP_002650096.1 silverDB:cEP03116 YP_002650097.1 silverDB:cEP03117 YP_002650098.1 silverDB:cEP03118 YP_002650099.1 silverDB:cEP03119 YP_002650100.1 silverDB:cEP03120 YP_002650101.1 silverDB:cEP03121 YP_002650102.1 silverDB:cEP03122 YP_002650103.1 silverDB:cEP03123 YP_002650104.1 silverDB:cEP03124 YP_002650105.1 silverDB:cEP03125 YP_002650106.1 silverDB:cEP03126 YP_002650107.1 silverDB:cEP03127 YP_002650108.1 silverDB:cEP03128 YP_002650109.1 silverDB:cEP03129 YP_002650110.1 silverDB:cEP03130 YP_002650111.1 silverDB:cEP03131 YP_002650112.1 silverDB:cEP03132 YP_002650113.1 silverDB:cEP03133 YP_002650114.1 silverDB:cEP03134 YP_002650115.1 silverDB:cEP03135 YP_002650116.1 silverDB:cEP03136 YP_002650117.1 silverDB:cEP03137 YP_002650118.1 silverDB:cEP03138 YP_002650119.1 silverDB:cEP03139 YP_002650120.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002650121.1 catalyzes the formation of L-homocysteine from cystathionine YP_002650122.1 silverDB:cEP03142 YP_002650123.1 silverDB:cEP03143 YP_002650124.1 silverDB:cEP03144 YP_002650125.1 silverDB:cEP03145 YP_002650126.1 silverDB:cEP03146 YP_002650127.1 silverDB:cEP03147 YP_002650128.1 silverDB:cEP03148 YP_002650129.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002650130.1 silverDB:cEP03150 YP_002650131.1 silverDB:cEP03151 YP_002650132.1 silverDB:cEP03152 YP_002650133.1 silverDB:cEP03153 YP_002650134.1 silverDB:cEP03154 YP_002650135.1 silverDB:cEP03155 YP_002650136.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002650137.1 silverDB:cEP03157 YP_002650138.1 silverDB:cEP03158 YP_002650139.1 silverDB:cEP03159 YP_002650140.1 silverDB:cEP03160 YP_002650141.1 silverDB:cEP03161 YP_002650142.1 silverDB:cEP03162 YP_002650143.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002650144.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_002650145.1 silverDB:cEP03165 YP_002650146.1 silverDB:cEP03166 YP_002650147.1 silverDB:cEP03167 YP_002650148.1 silverDB:cEP03168 YP_002650149.1 silverDB:cEP03169 YP_002650150.1 silverDB:cEP03170 YP_002650151.1 silverDB:cEP03171 YP_002650152.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002650153.1 silverDB:cEP03173 YP_002650154.1 silverDB:cEP03174 YP_002650155.1 silverDB:cEP03175 YP_002650156.1 silverDB:cEP03176 YP_002650157.1 silverDB:cEP03177 YP_002650158.1 silverDB:cEP03178 YP_002650159.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002650160.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_002650161.1 silverDB:cEP03181 YP_002650162.1 silverDB:cEP03182 YP_002650163.1 silverDB:cEP03183 YP_002650164.1 silverDB:cEP03184 YP_002650165.1 silverDB:cEP03185 YP_002650166.1 silverDB:cEP03186 YP_002650167.1 silverDB:cEP03187 YP_002650168.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002650169.1 silverDB:cEP03189 YP_002650170.1 silverDB:cEP03190 YP_002650171.1 silverDB:cEP03191 YP_002650172.1 silverDB:cEP03192 YP_002650173.1 silverDB:cEP03193 YP_002650174.1 silverDB:cEP03194 YP_002650175.1 silverDB:cEP03195 YP_002650176.1 silverDB:cEP03196 YP_002650177.1 silverDB:cEP03197 YP_002650178.1 silverDB:cEP03198 YP_002650179.1 silverDB:cEP03199 YP_002650180.1 silverDB:cEP03200 YP_002650181.1 silverDB:cEP03201 YP_002650182.1 silverDB:cEP03202 YP_002650183.1 silverDB:cEP03203 YP_002650184.1 silverDB:cEP03204 YP_002650185.1 silverDB:cEP03205 YP_002650186.1 silverDB:cEP03206 YP_002650187.1 silverDB:cEP03207 YP_002650188.1 silverDB:cEP03208 YP_002650189.1 silverDB:cEP03209 YP_002650190.1 silverDB:cEP03210 YP_002650191.1 silverDB:cEP03211 YP_002650192.1 silverDB:cEP03212 YP_002650193.1 silverDB:cEP03213 YP_002650194.1 silverDB:cEP03214 YP_002650195.1 silverDB:cEP03215 YP_002650196.1 silverDB:cEP03216 YP_002650197.1 silverDB:cEP03217 YP_002650198.1 silverDB:cEP03218 YP_002650199.1 silverDB:cEP03219 YP_002650200.1 silverDB:cEP03220 YP_002650201.1 silverDB:cEP03221 YP_002650202.1 silverDB:cEP03222 YP_002650203.1 silverDB:cEP03223 YP_002650204.1 silverDB:cEP03224 YP_002650205.1 silverDB:cEP03225 YP_002650206.1 silverDB:cEP03226 YP_002650207.1 silverDB:cEP03227 YP_002650208.1 silverDB:cEP03228 YP_002650209.1 silverDB:cEP03229 YP_002650210.1 silverDB:cEP03230 YP_002650211.1 silverDB:cEP03231 YP_002650212.1 silverDB:cEP03232 YP_002650213.1 silverDB:cEP03233 YP_002650214.1 silverDB:cEP03234 YP_002650215.1 silverDB:cEP03235 YP_002650216.1 silverDB:cEP03236 YP_002650217.1 silverDB:cEP03237 YP_002650218.1 silverDB:cEP03238 YP_002650219.1 silverDB:cEP03239 YP_002650220.1 silverDB:cEP03240 YP_002650221.1 silverDB:cEP03241 YP_002650222.1 silverDB:cEP03242 YP_002650223.1 silverDB:cEP03243 YP_002650224.1 silverDB:cEP03244 YP_002650225.1 silverDB:cEP03245 YP_002650226.1 silverDB:cEP03246 YP_002650227.1 silverDB:cEP03247 YP_002650228.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_002650229.1 silverDB:cEP03249 YP_002650230.1 silverDB:cEP03250 YP_002650231.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_002650232.1 silverDB:cEP03252 YP_002650233.1 silverDB:cEP03253 YP_002650234.1 silverDB:cEP03254 YP_002650235.1 silverDB:cEP03255 YP_002650236.1 silverDB:cEP03256 YP_002650237.1 silverDB:cEP03257 YP_002650238.1 silverDB:cEP03258 YP_002650239.1 silverDB:cEP03259 YP_002650240.1 silverDB:cEP03260 YP_002650241.1 silverDB:cEP03261 YP_002650242.1 silverDB:cEP03262 YP_002650243.1 silverDB:cEP03263 YP_002650244.1 silverDB:cEP03264 YP_002650245.1 silverDB:cEP03265 YP_002650246.1 silverDB:cEP03266 YP_002650247.1 silverDB:cEP03267 YP_002650248.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_002650249.1 silverDB:cEP03269 YP_002650250.1 silverDB:cEP03270 YP_002650251.1 silverDB:cEP03271 YP_002650252.1 silverDB:cEP03272 YP_002650253.1 silverDB:cEP03273 YP_002650254.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002650255.1 silverDB:cEP03275 YP_002650256.1 silverDB:cEP03276 YP_002650257.1 silverDB:cEP03277 YP_002650258.1 silverDB:cEP03278 YP_002650259.1 silverDB:cEP03279 YP_002650260.1 silverDB:cEP03280 YP_002650261.1 silverDB:cEP03281 YP_002650262.1 silverDB:cEP03282 YP_002650263.1 silverDB:cEP03283 YP_002650264.1 regulates genes involved in response to oxidative stress YP_002650265.1 silverDB:cEP03285 YP_002650266.1 silverDB:cEP03286 YP_002650267.1 silverDB:cEP03287 YP_002650268.1 silverDB:cEP03288 YP_002650269.1 silverDB:cEP03289 YP_002650270.1 silverDB:cEP03290 YP_002650271.1 silverDB:cEP03291 YP_002650272.1 silverDB:cEP03292 YP_002650273.1 silverDB:cEP03293 YP_002650274.1 silverDB:cEP03294 YP_002650275.1 silverDB:cEP03295 YP_002650276.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002650277.1 silverDB:cEP03297 YP_002650278.1 silverDB:cEP03298 YP_002650279.1 silverDB:cEP03299 YP_002650280.1 silverDB:cEP03300 YP_002650281.1 silverDB:cEP03301 YP_002650282.1 silverDB:cEP03302 YP_002650283.1 silverDB:cEP03303 YP_002650284.1 silverDB:cEP03304 YP_002650285.1 silverDB:cEP03305 YP_002650286.1 silverDB:cEP03306 YP_002650287.1 silverDB:cEP03307 YP_002650288.1 silverDB:cEP03308 YP_002650289.1 silverDB:cEP03309 YP_002650290.1 silverDB:cEP03310 YP_002650291.1 silverDB:cEP03311 YP_002650292.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002650293.1 silverDB:cEP03313 YP_002650294.1 silverDB:cEP03314 YP_002650295.1 silverDB:cEP03315 YP_002650296.1 silverDB:cEP03316 YP_002650297.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_002650298.1 silverDB:cEP03318 YP_002650299.1 silverDB:cEP03319 YP_002650300.1 silverDB:cEP03320 YP_002650301.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_002650302.1 silverDB:cEP03322 YP_002650303.1 Represses a number of genes involved in the response to DNA damage YP_002650304.1 silverDB:cEP03324 YP_002650305.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002650306.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_002650307.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_002650308.1 silverDB:cEP03328 YP_002650309.1 silverDB:cEP03329 YP_002650310.1 silverDB:cEP03330 YP_002650311.1 silverDB:cEP03331 YP_002650312.1 silverDB:cEP03332 YP_002650313.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002650314.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_002650315.1 silverDB:cEP03335 YP_002650316.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002650317.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002650318.1 silverDB:cEP03338 YP_002650319.1 silverDB:cEP03339 YP_002650320.1 silverDB:cEP03340 YP_002650321.1 silverDB:cEP03341 YP_002650322.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002650323.1 silverDB:cEP03343 YP_002650324.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_002650325.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002650326.1 silverDB:cEP03346 YP_002650327.1 silverDB:cEP03347 YP_002650328.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_002650329.1 silverDB:cEP03349 YP_002650330.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002650331.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002650332.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions protein NusA in antitermination YP_002650333.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002650334.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002650335.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002650336.1 late assembly protein YP_002650337.1 silverDB:cEP03357 YP_002650338.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002650339.1 binds 5S rRNA along with protein L5 and L25 YP_002650340.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002650341.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002650342.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002650343.1 silverDB:cEP03363 YP_002650344.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002650345.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002650346.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002650347.1 silverDB:cEP03367 YP_002650348.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; archaeal L10e YP_002650349.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002650350.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002650351.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002650352.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002650353.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002650354.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002650355.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002650356.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002650357.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002650358.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002650359.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002650360.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002650361.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002650362.1 silverDB:cEP03382 YP_002650363.1 silverDB:cEP03383 YP_002650364.1 silverDB:cEP03384 YP_002650365.1 rotamase YP_002650366.1 silverDB:cEP03386 YP_002650367.1 rotamase YP_002650368.1 silverDB:cEP03388 YP_002650369.1 involved in potassium efflux YP_002650370.1 required for KefB activity YP_002650371.1 silverDB:cEP03391 YP_002650372.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_002650373.1 silverDB:cEP03393 YP_002650374.1 silverDB:cEP03394 YP_002650375.1 silverDB:cEP03395 YP_002650376.1 silverDB:cEP03396 YP_002650377.1 silverDB:cEP03397 YP_002650378.1 silverDB:cEP03398 YP_002650379.1 silverDB:cEP03399 YP_002650380.1 silverDB:cEP03400 YP_002650381.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002650382.1 silverDB:cEP03402 YP_002650383.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_002650384.1 silverDB:cEP03404 YP_002650385.1 silverDB:cEP03405 YP_002650386.1 silverDB:cEP03406 YP_002650387.1 silverDB:cEP03407 YP_002650388.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002650389.1 silverDB:cEP03409 YP_002650390.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002650391.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002650392.1 silverDB:cEP03412 YP_002650393.1 silverDB:cEP03413 YP_002650394.1 silverDB:cEP03414 YP_002650395.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002650396.1 type I enzyme type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002650397.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_002650398.1 silverDB:cEP03418 YP_002650399.1 silverDB:cEP03419 YP_002650400.1 silverDB:cEP03420 YP_002650401.1 silverDB:cEP03421 YP_002650402.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_002650403.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002650404.1 silverDB:cEP03424 YP_002650405.1 silverDB:cEP03425 YP_002650406.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002650407.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002650408.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002650409.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002650410.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002650411.1 silverDB:cEP03431 YP_002650412.1 silverDB:cEP03432 YP_002650413.1 silverDB:cEP03433 YP_002650414.1 silverDB:cEP03434 YP_002650415.1 silverDB:cEP03435 YP_002650416.1 silverDB:cEP03436 YP_002650417.1 silverDB:cEP03437 YP_002650418.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002650419.1 amylomaltase; acts to release glucose from maltodextrins YP_002650420.1 silverDB:cEP03440 YP_002650421.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_002650422.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_002650423.1 silverDB:cEP03443 YP_002650424.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002650425.1 silverDB:cEP03445 YP_002650426.1 silverDB:cEP03446 YP_002650427.1 silverDB:cEP03447 YP_002650428.1 silverDB:cEP03448 YP_002650429.1 silverDB:cEP03449 YP_002650430.1 silverDB:cEP03450 YP_002650431.1 silverDB:cEP03451 YP_002650432.1 silverDB:cEP03452 YP_002650433.1 silverDB:cEP03453 YP_002650434.1 silverDB:cEP03454 YP_002650435.1 silverDB:cEP03455 YP_002650436.1 silverDB:cEP03456 YP_002650437.1 silverDB:cEP03457 YP_002650438.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002650439.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002650440.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_002650441.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002650442.1 silverDB:cEP03462 YP_002650443.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002650444.1 silverDB:cEP03464 YP_002650445.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_002650446.1 silverDB:cEP03466 YP_002650447.1 silverDB:cEP03467 YP_002650448.1 silverDB:cEP03468 YP_002650449.1 silverDB:cEP03469 YP_002650450.1 silverDB:cEP03470 YP_002650451.1 silverDB:cEP03471 YP_002650452.1 silverDB:cEP03472 YP_002650453.1 silverDB:cEP03473 YP_002650454.1 silverDB:cEP03474 YP_002650455.1 silverDB:cEP03475 YP_002650456.1 silverDB:cEP03476 YP_002650457.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002650458.1 silverDB:cEP03478 YP_002650459.1 silverDB:cEP03479 YP_002650460.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002650461.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002650462.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002650463.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_002650464.1 silverDB:cEP03484 YP_002650465.1 silverDB:cEP03485 YP_002650466.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002650467.1 ABC transporter membrane protein YP_002650468.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_002650469.1 silverDB:cEP03489 YP_002650470.1 catalyzes the methylation of 16S rRNA at position G966 YP_002650471.1 silverDB:cEP03491 YP_002650472.1 silverDB:cEP03492 YP_002650473.1 silverDB:cEP03493 YP_002650474.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_002650475.1 silverDB:cEP03495 YP_002650476.1 silverDB:cEP03496 YP_002650477.1 silverDB:cEP03497 YP_002650478.1 silverDB:cEP03498 YP_002650479.1 silverDB:cEP03499 YP_002650480.1 silverDB:cEP03500 YP_002650481.1 silverDB:cEP03501 YP_002650482.1 silverDB:cEP03502 YP_002650483.1 silverDB:cEP03503 YP_002650484.1 silverDB:cEP03504 YP_002650485.1 silverDB:cEP03505 YP_002650486.1 silverDB:cEP03506 YP_002650487.1 silverDB:cEP03507 YP_002650488.1 silverDB:cEP03508 YP_002650489.1 silverDB:cEP03509 YP_002650490.1 silverDB:cEP03510 YP_002650491.1 silverDB:cEP03511 YP_002650492.1 silverDB:cEP03512 YP_002650493.1 silverDB:cEP03513 YP_002650494.1 silverDB:cEP03514 YP_002650495.1 silverDB:cEP03515 YP_002650496.1 catalyzes the formation of L-proline from L-ornithine YP_002650497.1 silverDB:cEP03517 YP_002650498.1 silverDB:cEP03518 YP_002650499.1 silverDB:cEP03519 YP_002650500.1 silverDB:cEP03520 YP_002650501.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_002650502.1 silverDB:cEP03522 YP_002650503.1 SAM-dependent methyltransferase YP_002650504.1 silverDB:cEP03524 YP_002650505.1 silverDB:cEP03525 YP_002650506.1 silverDB:cEP03526 YP_002650507.1 silverDB:cEP03527 YP_002650508.1 silverDB:cEP03528 YP_002650509.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002650510.1 silverDB:cEP03530 YP_002650511.1 silverDB:cEP03531 YP_002650512.1 silverDB:cEP03532 YP_002650513.1 silverDB:cEP03533 YP_002650514.1 silverDB:cEP03534 YP_002650515.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002650516.1 silverDB:cEP03536 YP_002650517.1 silverDB:cEP03537 YP_002650518.1 silverDB:cEP03538 YP_002650519.1 silverDB:cEP03539 YP_002650520.1 silverDB:cEP03540 YP_002650521.1 silverDB:cEP03541 YP_002650522.1 silverDB:cEP03542 YP_002650523.1 silverDB:cEP03543 YP_002650524.1 silverDB:cEP03544 YP_002650525.1 silverDB:cEP03545 YP_002650526.1 silverDB:cEP03546 YP_002650527.1 silverDB:cEP03547 YP_002650528.1 silverDB:cEP03548 YP_002650529.1 silverDB:cEP03549 YP_002650530.1 silverDB:cEP03550 YP_002650531.1 silverDB:cEP03551 YP_002650532.1 silverDB:cEP03552 YP_002650533.1 silverDB:cEP03553 YP_002650534.1 silverDB:cEP03554 YP_002650535.1 silverDB:cEP03555 YP_002650536.1 silverDB:cEP03556 YP_002650537.1 silverDB:cEP03557 YP_002650538.1 silverDB:cEP03558 YP_002650539.1 silverDB:cEP03559 YP_002650540.1 silverDB:cEP03560 YP_002650541.1 silverDB:cEP03561 YP_002650542.1 silverDB:cEP03562 YP_002650543.1 silverDB:cEP03563 YP_002650544.1 silverDB:cEP03564 YP_002650545.1 silverDB:cEP03565 YP_002650546.1 silverDB:cEP03566 YP_002650547.1 silverDB:cEP03567 YP_002650548.1 silverDB:cEP03568 YP_002650549.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_002650550.1 silverDB:cEP03570 YP_002650551.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002650552.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002650553.1 silverDB:cEP03573 YP_002650554.1 silverDB:cEP03574 YP_002650555.1 silverDB:cEP03575 YP_002650556.1 silverDB:cEP03576 YP_002650557.1 silverDB:cEP03577 YP_002650558.1 silverDB:cEP03578 YP_002650559.1 silverDB:cEP03579 YP_002650560.1 silverDB:cEP03580 YP_002650561.1 silverDB:cEP03581 YP_002650562.1 silverDB:cEP03582 YP_002650563.1 silverDB:cEP03583 YP_002650564.1 silverDB:cEP03584 YP_002650565.1 silverDB:cEP03585 YP_002650566.1 silverDB:cEP03586 YP_002650567.1 silverDB:cEP03587 YP_002650568.1 silverDB:cEP03588 YP_002650569.1 silverDB:cEP03589 YP_002650570.1 silverDB:cEP03590 YP_002650571.1 silverDB:cEP03591 YP_002650572.1 silverDB:cEP03592 YP_002650573.1 in Escherichia coli this protein is involved in flagellar function YP_002650574.1 silverDB:cEP03594 YP_002650575.1 silverDB:cEP03595 YP_002650576.1 involved in the transport of C4-dicarboxylates across the membrane YP_002650577.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; a phosphodiesterase protein from E. coli YP_002650578.1 silverDB:cEP03598 YP_002650579.1 silverDB:cEP03599 YP_002650580.1 silverDB:cEP03600 YP_002650581.1 silverDB:cEP03601 YP_002650582.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_002650583.1 silverDB:cEP03603 YP_002650584.1 silverDB:cEP03604 YP_002650585.1 silverDB:cEP03605 YP_002650586.1 silverDB:cEP03606 YP_002650587.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002650588.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_002650589.1 silverDB:cEP03609 YP_002650590.1 transports peptides consisting of two or three amino acids YP_002650591.1 silverDB:cEP03611 YP_002650592.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_002650593.1 silverDB:cEP03613 YP_002650594.1 silverDB:cEP03614 YP_002650595.1 silverDB:cEP03615 YP_002650596.1 silverDB:cEP03616 YP_002650597.1 silverDB:cEP03617 YP_002650598.1 silverDB:cEP03618 YP_002650599.1 silverDB:cEP03619 YP_002650600.1 silverDB:cEP03620 YP_002650601.1 silverDB:cEP03621 YP_002650602.1 silverDB:cEP03622 YP_002650603.1 silverDB:cEP03623 YP_002650604.1 silverDB:cEP03624 YP_002650605.1 silverDB:cEP03625 YP_002650606.1 silverDB:cEP03626 YP_002650607.1 silverDB:cEP03627 YP_002650608.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002650609.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002650610.1 silverDB:cEP03630 YP_002650611.1 silverDB:cEP03631 YP_002650612.1 silverDB:cEP03632 YP_002650613.1 silverDB:cEP03633 YP_002650614.1 silverDB:cEP03634 YP_002650615.1 silverDB:cEP03635 YP_002650616.1 Acts as a repressor of the mtlAD operon YP_002650617.1 silverDB:cEP03637 YP_002650618.1 silverDB:cEP03638 YP_002650619.1 silverDB:cEP03639 YP_002650620.1 silverDB:cEP03640 YP_002650621.1 silverDB:cEP03641 YP_002650622.1 silverDB:cEP03642 YP_002650623.1 silverDB:cEP03643 YP_002650624.1 silverDB:cEP03644 YP_002650625.1 silverDB:cEP03645 YP_002650626.1 silverDB:cEP03646 YP_002650627.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002650628.1 silverDB:cEP03648 YP_002650629.1 required for the formation of active formate dehydrogenase YP_002650630.1 silverDB:cEP03650 YP_002650631.1 silverDB:cEP03651 YP_002650632.1 silverDB:cEP03652 YP_002650633.1 silverDB:cEP03653 YP_002650634.1 silverDB:cEP03654 YP_002650635.1 silverDB:cEP03655 YP_002650636.1 silverDB:cEP03656 YP_002650637.1 silverDB:cEP03657 YP_002650638.1 silverDB:cEP03658 YP_002650639.1 silverDB:cEP03659 YP_002650640.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_002650641.1 silverDB:cEP03661 YP_002650642.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_002650643.1 silverDB:cEP03663 YP_002650644.1 silverDB:cEP03664 YP_002650645.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_002650646.1 silverDB:cEP03666 YP_002650647.1 silverDB:cEP03667 YP_002650648.1 negatively supercoils closed circular double-stranded DNA YP_002650649.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002650650.1 binds the polymerase to DNA and acts as a sliding clamp YP_002650651.1 silverDB:cEP03671 YP_002650652.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002650653.1 silverDB:cEP03673 YP_002650654.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; Oxa1p in mitochondria YP_002650655.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002650656.1 silverDB:cEP03676 YP_002650657.1 silverDB:cEP03677 YP_002650658.1 silverDB:cEP03678 YP_002650659.1 silverDB:cEP03679 YP_002650660.1 silverDB:cEP03680 YP_002650661.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002650662.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002650663.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002650664.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002650665.1 silverDB:cEP03685 YP_002650666.1 silverDB:cEP03686 YP_002650667.1 silverDB:cEP03687 YP_002650668.1 silverDB:cEP03688 YP_002650669.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002650670.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002650671.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002650672.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002650673.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002650674.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002650675.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002650676.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002650677.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002650678.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002650679.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_002650680.1 silverDB:cEP03700 YP_002650681.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002650682.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002650683.1 silverDB:cEP03703 YP_003208061.1 silverDB:pEP36G00002 YP_003208062.1 silverDB:pEP36G00003 YP_003208063.1 silverDB:pEP36G00004 YP_003208064.1 silverDB:pEP36G00005 YP_003208065.1 silverDB:pEP36G00006 YP_003208066.1 silverDB:pEP36G00007 YP_003208067.1 silverDB:pEP36G00009 YP_003208068.1 silverDB:pEP36G00010 YP_003208069.1 silverDB:pEP36G00011 YP_003208070.1 silverDB:pEP36G00012 YP_003208071.1 silverDB:pEP36G00013 YP_003208072.1 silverDB:pEP36G00014 YP_003208073.1 silverDB:pEP36G00015 YP_003208074.1 silverDB:pEP36G00016 YP_003208075.1 silverDB:pEP36G00017 YP_003208076.1 silverDB:pEP36G00018 YP_003208077.1 silverDB:pEP36G00019 YP_003208078.1 silverDB:pEP36G00020 YP_003208079.1 silverDB:pEP36G00021 YP_003208080.1 silverDB:pEP36G00022 YP_003208081.1 silverDB:pEP36G00023 YP_003208082.1 silverDB:pEP36G00024 YP_003208083.1 silverDB:pEP36G00025 YP_003208084.1 silverDB:pEP36G00026 YP_003208085.1 silverDB:pEP36G00027 YP_003208086.1 silverDB:pEP36G00028 YP_003208087.1 silverDB:pEP36G00029 YP_003208088.1 silverDB:pEP36G00030 YP_003208089.1 silverDB:pEP36G00031 YP_003208090.1 silverDB:pEP36G00032 YP_003208091.1 silverDB:pEP36G00033 YP_003208092.1 silverDB:pEP36G00034 YP_003208093.1 silverDB:pEP36G00035 YP_003208094.1 silverDB:pEP36G00036 YP_003208095.1 silverDB:pEP36G00001 YP_003208096.1 silverDB:pEP36G00037 YP_003208097.1 silverDB:pEP36G00038 YP_003208098.1 silverDB:pEP03G00001 YP_003208099.1 silverDB:pEP03G00002 YP_003208100.1 silverDB:pEP03G00003 YP_003208101.1 silverDB:pEP03G00004 YP_003208102.1 silverDB:pEP05G00002 YP_003208103.1 silverDB:pEP05G00003 YP_003208104.1 silverDB:pEP05G00004 YP_003208105.1 silverDB:pEP05G00005 YP_003208106.1 silverDB:pEP05G00001