-- dump date 20140619_080708 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 362663000001 SEQ_END SEQ_END NC_008253.1 4938920 4938920 DR NC_008253.1; contig end 4938920..4938920 Escherichia coli 536 YP_667942.1 CDS ECP_0001 NC_008253.1 190 255 D thr operon leader peptide 190..255 Escherichia coli 536 4190978 YP_667943.1 CDS thrA NC_008253.1 336 2798 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 336..2798 Escherichia coli 536 4190979 YP_667944.1 CDS ECP_0003 NC_008253.1 2800 3732 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2800..3732 Escherichia coli 536 4190980 YP_667945.1 CDS ECP_0004 NC_008253.1 3733 5019 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3733..5019 Escherichia coli 536 4190981 YP_667946.1 CDS ECP_0005 NC_008253.1 5058 5237 D hypothetical protein 5058..5237 Escherichia coli 536 4190982 YP_667947.1 CDS ECP_0006 NC_008253.1 5243 5530 D periplasmic protein YaaX 5243..5530 Escherichia coli 536 4190983 YP_667948.1 CDS ECP_0007 NC_008253.1 5580 6356 R hypothetical protein complement(5580..6356) Escherichia coli 536 4190984 YP_667949.1 CDS ECP_0008 NC_008253.1 6426 7856 R transporter YaaJ complement(6426..7856) Escherichia coli 536 4190985 YP_667950.1 CDS ECP_0009 NC_008253.1 8137 9090 D transaldolase B 8137..9090 Escherichia coli 536 4190986 YP_667951.1 CDS mogA NC_008253.1 9205 9792 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein 9205..9792 Escherichia coli 536 4190987 YP_667952.1 CDS ECP_0011 NC_008253.1 9997 10563 R regulator; hypothetical protein complement(9997..10563) Escherichia coli 536 4190988 YP_667953.1 CDS ECP_0012 NC_008253.1 10712 11425 R hypothetical protein complement(10712..11425) Escherichia coli 536 4190989 YP_667954.1 CDS ECP_0013 NC_008253.1 11451 11855 R hypothetical protein complement(11451..11855) Escherichia coli 536 4190990 YP_667955.1 CDS dnaK NC_008253.1 12227 14143 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12227..14143 Escherichia coli 536 4190991 YP_667956.2 CDS ECP_0015 NC_008253.1 14232 15362 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 14232..15362 Escherichia coli 536 4190992 YP_667958.1 CDS ECP_0017 NC_008253.1 16234 16995 D hypothetical protein 16234..16995 Escherichia coli 536 4190994 YP_667959.1 CDS ECP_0018 NC_008253.1 17015 18508 D secreted sulfatase 17015..18508 Escherichia coli 536 4190995 YP_667960.1 CDS ECP_0019 NC_008253.1 18637 19896 D hypothetical protein 18637..19896 Escherichia coli 536 4187264 YP_667961.1 CDS nhaA NC_008253.1 20131 21297 D Na(+)/H(+) antiporter 1; exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 20131..21297 Escherichia coli 536 4187265 YP_667962.1 CDS nhaR NC_008253.1 21357 22262 D Na+/H+ antiporter regulatory protein; Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 21357..22262 Escherichia coli 536 4187266 YP_667963.1 CDS rpsT NC_008253.1 22358 22621 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(22358..22621) Escherichia coli 536 4187267 YP_667964.1 CDS ECP_0023 NC_008253.1 22950 23891 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 22950..23891 Escherichia coli 536 4187268 YP_667965.1 CDS ileS NC_008253.1 23934 26750 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 23934..26750 Escherichia coli 536 4187269 YP_667966.1 CDS lspA NC_008253.1 26750 27244 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 26750..27244 Escherichia coli 536 4187270 YP_667967.1 CDS ECP_0026 NC_008253.1 27352 27801 D FKBP-type peptidylprolyl isomerase 27352..27801 Escherichia coli 536 4187271 YP_667968.1 CDS ECP_0027 NC_008253.1 27803 28768 D LytB protein 27803..28768 Escherichia coli 536 4187272 YP_667969.1 CDS ECP_0028 NC_008253.1 28818 29732 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 28818..29732 Escherichia coli 536 4187273 YP_667970.1 CDS ECP_0029 NC_008253.1 29899 30720 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 29899..30720 Escherichia coli 536 4187274 YP_667971.1 CDS ECP_0030 NC_008253.1 30781 31023 D hypothetical protein 30781..31023 Escherichia coli 536 4187275 YP_667972.1 CDS ECP_0031 NC_008253.1 31176 32324 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 31176..32324 Escherichia coli 536 4187276 YP_667973.1 CDS carB NC_008253.1 32342 35560 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 32342..35560 Escherichia coli 536 4187277 YP_667974.1 CDS ECP_0033 NC_008253.1 35568 35786 R hypothetical protein complement(35568..35786) Escherichia coli 536 4187278 YP_667975.1 CDS ECP_0034 NC_008253.1 35821 36216 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 35821..36216 Escherichia coli 536 4187279 YP_667976.1 CDS ECP_0035 NC_008253.1 36335 36925 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(36335..36925) Escherichia coli 536 4187280 YP_667977.1 CDS ECP_0036 NC_008253.1 36931 37716 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(36931..37716) Escherichia coli 536 4187281 YP_667978.1 CDS caiC NC_008253.1 37825 39393 R crotonobetaine/carnitine-CoA ligase complement(37825..39393) Escherichia coli 536 4187282 YP_667979.1 CDS ECP_0038 NC_008253.1 39451 40668 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(39451..40668) Escherichia coli 536 4187283 YP_667980.1 CDS ECP_0039 NC_008253.1 40786 41928 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(40786..41928) Escherichia coli 536 4189945 YP_667981.1 CDS ECP_0040 NC_008253.1 41959 43473 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(41959..43473) Escherichia coli 536 4189946 YP_667982.1 CDS ECP_0041 NC_008253.1 43946 44716 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 43946..44716 Escherichia coli 536 4189947 YP_667983.1 CDS fixB NC_008253.1 44731 45672 D carnitine metabolism; involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 44731..45672 Escherichia coli 536 4189948 YP_667984.1 CDS ECP_0043 NC_008253.1 45723 47009 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 45723..47009 Escherichia coli 536 4189949 YP_667985.1 CDS ECP_0044 NC_008253.1 47006 47293 D ferredoxin-like protein 47006..47293 Escherichia coli 536 4189950 YP_667986.1 CDS ECP_0045 NC_008253.1 47352 48683 D metabolite transport protein YaaU 47352..48683 Escherichia coli 536 4189951 YP_667987.1 CDS ECP_0046 NC_008253.1 48791 49321 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 48791..49321 Escherichia coli 536 4189952 YP_667988.1 CDS ECP_0047 NC_008253.1 49314 51176 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 49314..51176 Escherichia coli 536 4189953 YP_667989.1 CDS folA NC_008253.1 51368 51847 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 51368..51847 Escherichia coli 536 4189954 YP_667990.1 CDS ECP_0049 NC_008253.1 51933 52166 D antitoxin of gyrase inhibiting toxin-antitoxin system 51933..52166 Escherichia coli 536 4189955 YP_667991.1 CDS ECP_0050 NC_008253.1 52169 52483 D toxin of gyrase inhibiting toxin-antitoxin system 52169..52483 Escherichia coli 536 4189956 YP_667992.1 CDS apaH NC_008253.1 52480 53328 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(52480..53328) Escherichia coli 536 4189957 YP_667993.1 CDS apaG NC_008253.1 53335 53712 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(53335..53712) Escherichia coli 536 4189958 YP_667994.1 CDS ksgA NC_008253.1 53715 54536 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(53715..54536) Escherichia coli 536 4189959 YP_667995.1 CDS pdxA NC_008253.1 54533 55501 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(54533..55501) Escherichia coli 536 4189960 YP_667996.1 CDS ECP_0057 NC_008253.1 56860 59214 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(56860..59214) Escherichia coli 536 4189774 YP_667997.1 CDS djlA NC_008253.1 59469 60284 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 59469..60284 Escherichia coli 536 4189775 YP_667998.1 CDS ECP_0059 NC_008253.1 60402 61061 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(60402..61061) Escherichia coli 536 4189776 YP_667999.1 CDS ECP_0060 NC_008253.1 61073 63979 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(61073..63979) Escherichia coli 536 4189777 YP_668000.1 CDS ECP_0061 NC_008253.1 64144 66495 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(64144..66495) Escherichia coli 536 4189778 YP_668001.1 CDS araD NC_008253.1 66570 67265 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(66570..67265) Escherichia coli 536 4189779 YP_668002.1 CDS ECP_0063 NC_008253.1 67550 69052 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(67550..69052) Escherichia coli 536 4189780 YP_668003.1 CDS ECP_0064 NC_008253.1 69063 70763 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(69063..70763) Escherichia coli 536 4189781 YP_668004.1 CDS ECP_0065 NC_008253.1 71102 71947 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 71102..71947 Escherichia coli 536 4189782 YP_668005.1 CDS ECP_0066 NC_008253.1 72461 73309 D hypothetical protein 72461..73309 Escherichia coli 536 4189783 YP_668006.1 CDS ECP_0067 NC_008253.1 73316 73738 D hypothetical protein 73316..73738 Escherichia coli 536 4189784 YP_668007.1 CDS ECP_0068 NC_008253.1 73893 74657 D DedA family integral membrane protein 73893..74657 Escherichia coli 536 4189785 YP_668008.1 CDS thiQ NC_008253.1 74771 75469 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(74771..75469) Escherichia coli 536 4189786 YP_668009.1 CDS thiP NC_008253.1 75453 77063 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(75453..77063) Escherichia coli 536 4189787 YP_668010.1 CDS tbpA NC_008253.1 77039 78022 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(77039..78022) Escherichia coli 536 4189788 YP_668011.1 CDS ECP_0072 NC_008253.1 78186 79841 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(78186..79841) Escherichia coli 536 4189789 YP_668012.1 CDS leuD NC_008253.1 80169 80774 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(80169..80774) Escherichia coli 536 4189790 YP_668013.1 CDS ECP_0074 NC_008253.1 80785 82185 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(80785..82185) Escherichia coli 536 4189791 YP_668014.1 CDS ECP_0075 NC_008253.1 82188 83279 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(82188..83279) Escherichia coli 536 4191365 YP_668015.1 CDS ECP_0076 NC_008253.1 83279 84850 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(83279..84850) Escherichia coli 536 4191366 YP_668016.1 CDS ECP_0077 NC_008253.1 84942 85028 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(84942..85028) Escherichia coli 536 4191367 YP_668017.1 CDS leuO NC_008253.1 85686 86630 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 85686..86630 Escherichia coli 536 4191368 YP_668018.1 CDS ECP_0079 NC_008253.1 86948 88672 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 86948..88672 Escherichia coli 536 4191369 YP_668019.1 CDS ilvH NC_008253.1 88675 89166 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 88675..89166 Escherichia coli 536 4191370 YP_668021.1 CDS ECP_0082 NC_008253.1 89346 90350 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 89346..90350 Escherichia coli 536 4191372 YP_668022.1 CDS ECP_0083 NC_008253.1 90952 91410 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 90952..91410 Escherichia coli 536 4191373 YP_668023.1 CDS mraW NC_008253.1 91412 92353 D S-adenosyl-methyltransferase MraW 91412..92353 Escherichia coli 536 4191374 YP_668024.1 CDS ECP_0085 NC_008253.1 92350 92715 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 92350..92715 Escherichia coli 536 4191375 YP_668025.1 CDS ECP_0086 NC_008253.1 92731 94497 D peptidoglycan synthetase FtsI 92731..94497 Escherichia coli 536 4191376 YP_668026.1 CDS murE NC_008253.1 94484 95971 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 94484..95971 Escherichia coli 536 4191377 YP_668027.1 CDS murF NC_008253.1 95968 97326 D UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 95968..97326 Escherichia coli 536 4191378 YP_668028.1 CDS mraY NC_008253.1 97320 98402 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 97320..98402 Escherichia coli 536 4191379 YP_668029.1 CDS murD NC_008253.1 98405 99721 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 98405..99721 Escherichia coli 536 4191380 YP_668030.1 CDS ECP_0091 NC_008253.1 99721 100965 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 99721..100965 Escherichia coli 536 4191381 YP_668031.1 CDS murG NC_008253.1 100962 102029 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 100962..102029 Escherichia coli 536 4191382 YP_668032.1 CDS murC NC_008253.1 102083 103558 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 102083..103558 Escherichia coli 536 4191383 YP_668033.1 CDS ddl NC_008253.1 103551 104471 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 103551..104471 Escherichia coli 536 4191384 YP_668034.1 CDS ECP_0095 NC_008253.1 104473 105303 D involved in septum formation; cell division protein FtsQ 104473..105303 Escherichia coli 536 4189640 YP_668035.1 CDS ftsA NC_008253.1 105300 106562 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 105300..106562 Escherichia coli 536 4189641 YP_668036.1 CDS ECP_0097 NC_008253.1 106623 107774 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 106623..107774 Escherichia coli 536 4189642 YP_668037.1 CDS lpxC NC_008253.1 107875 108792 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 107875..108792 Escherichia coli 536 4189643 YP_668038.1 CDS ECP_0099 NC_008253.1 109023 109535 D regulates SecA expression; secM translational pause allows for the initiation of secA translation; SecA regulator SecM 109023..109535 Escherichia coli 536 4189644 YP_668039.1 CDS secA NC_008253.1 109597 112302 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 109597..112302 Escherichia coli 536 4189645 YP_668040.1 CDS ECP_0101 NC_008253.1 112362 112760 D nucleoside triphosphate pyrophosphohydrolase 112362..112760 Escherichia coli 536 4189646 YP_668041.1 CDS ECP_0102 NC_008253.1 112848 113045 R zinc-binding protein complement(112848..113045) Escherichia coli 536 4189647 YP_668042.1 CDS ECP_0103 NC_008253.1 113055 113798 R hypothetical protein complement(113055..113798) Escherichia coli 536 4189648 YP_668043.1 CDS coaE NC_008253.1 113798 114418 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(113798..114418) Escherichia coli 536 4189649 YP_668044.1 CDS ECP_0105 NC_008253.1 114643 115686 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 114643..115686 Escherichia coli 536 4189650 YP_668045.1 CDS ECP_0106 NC_008253.1 115721 116923 R type IV pilin biogenesis protein complement(115721..116923) Escherichia coli 536 4189651 YP_668046.1 CDS ECP_0107 NC_008253.1 116913 118298 R hypothetical protein complement(116913..118298) Escherichia coli 536 4189652 YP_668047.1 CDS ECP_0108 NC_008253.1 118308 118748 R major pilin subunit complement(118308..118748) Escherichia coli 536 4189653 YP_668048.1 CDS ECP_0109 NC_008253.1 118952 119845 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(118952..119845) Escherichia coli 536 4189654 YP_668049.1 CDS ECP_0110 NC_008253.1 119933 120484 D N-acetyl-anhydromuranmyl-L-alanine amidase 119933..120484 Escherichia coli 536 4189655 YP_668050.1 CDS ECP_0111 NC_008253.1 120481 121335 D transmembrane protein; involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 120481..121335 Escherichia coli 536 4189656 YP_668051.1 CDS ECP_0112 NC_008253.1 121378 122748 R aromatic amino acid transporter complement(121378..122748) Escherichia coli 536 4189657 YP_668052.1 CDS ECP_0113 NC_008253.1 123276 125057 D colicin 123276..125057 Escherichia coli 536 4189658 YP_668053.1 CDS ECP_0114 NC_008253.1 125060 125344 D colicin immunity protein 125060..125344 Escherichia coli 536 4190874 YP_668054.1 CDS ECP_0115 NC_008253.1 125512 125751 D uropathogenic specific protein 125512..125751 Escherichia coli 536 4190875 YP_668055.1 CDS ECP_0116 NC_008253.1 125752 126042 D colicin immunity protein 125752..126042 Escherichia coli 536 4190876 YP_668056.1 CDS ECP_0117 NC_008253.1 126227 126397 D uropathogenic specific protein 126227..126397 Escherichia coli 536 4190877 YP_668057.1 CDS ECP_0118 NC_008253.1 126451 126741 D colicin immunity protein 126451..126741 Escherichia coli 536 4190878 YP_668058.1 CDS pdhR NC_008253.1 127197 127961 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 127197..127961 Escherichia coli 536 4190879 YP_668059.1 CDS ECP_0120 NC_008253.1 127958 128140 R hypothetical protein complement(127958..128140) Escherichia coli 536 4190880 YP_668060.1 CDS aceE NC_008253.1 128122 130785 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 128122..130785 Escherichia coli 536 4190881 YP_668061.1 CDS aceF NC_008253.1 130800 132692 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 130800..132692 Escherichia coli 536 4190882 YP_668062.1 CDS ECP_0123 NC_008253.1 132900 134324 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 132900..134324 Escherichia coli 536 4190883 YP_668063.1 CDS ECP_0124 NC_008253.1 134566 136323 R hypothetical protein complement(134566..136323) Escherichia coli 536 4190884 YP_668064.1 CDS ECP_0125 NC_008253.1 136678 139275 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 136678..139275 Escherichia coli 536 4190885 YP_668065.1 CDS ECP_0126 NC_008253.1 139450 139812 D hypothetical protein 139450..139812 Escherichia coli 536 4190886 YP_668066.1 CDS ECP_0127 NC_008253.1 139850 140644 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(139850..140644) Escherichia coli 536 4190887 YP_668067.1 CDS ECP_0128 NC_008253.1 140660 141526 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(140660..141526) Escherichia coli 536 4190888 YP_668068.1 CDS ECP_0129 NC_008253.1 141632 141979 R hypothetical protein complement(141632..141979) Escherichia coli 536 4190889 YP_668069.1 CDS ECP_0130 NC_008253.1 142145 143695 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 142145..143695 Escherichia coli 536 4190890 YP_668070.1 CDS ECP_0131 NC_008253.1 143685 143867 R hypothetical protein complement(143685..143867) Escherichia coli 536 4190891 YP_668071.1 CDS ECP_0132 NC_008253.1 143952 146342 R glucose dehydrogenase complement(143952..146342) Escherichia coli 536 4190892 YP_668072.1 CDS ECP_0133 NC_008253.1 146652 147083 D hypoxanthine phosphoribosyltransferase 146652..147083 Escherichia coli 536 4190893 YP_668073.1 CDS ECP_0134 NC_008253.1 147124 147786 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(147124..147786) Escherichia coli 536 4189963 YP_668074.1 CDS ECP_0135 NC_008253.1 147895 148821 D ABC transporter ATP-binding protein 147895..148821 Escherichia coli 536 4189964 YP_668075.1 CDS ECP_0136 NC_008253.1 148818 149588 D ABC transporter membrane protein 148818..149588 Escherichia coli 536 4189965 YP_668076.1 CDS ECP_0137 NC_008253.1 149693 150133 D PTS system IIA component Yadi 149693..150133 Escherichia coli 536 4189966 YP_668077.1 CDS ECP_0138 NC_008253.1 150197 151426 D YadE protein, polysaccharide deacetylase 150197..151426 Escherichia coli 536 4189967 YP_668078.1 CDS ECP_0139 NC_008253.1 151430 151810 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(151430..151810) Escherichia coli 536 4189968 YP_668079.1 CDS ECP_0140 NC_008253.1 152084 153016 D hypothetical protein 152084..153016 Escherichia coli 536 4189969 YP_668080.1 CDS ECP_0141 NC_008253.1 153085 153288 D transposase, YhgA-like 153085..153288 Escherichia coli 536 4189970 YP_668081.1 CDS panC NC_008253.1 153370 154221 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(153370..154221) Escherichia coli 536 4189971 YP_668082.1 CDS panB NC_008253.1 154233 155027 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(154233..155027) Escherichia coli 536 4189972 YP_668083.1 CDS ECP_0144 NC_008253.1 155139 155453 R hypothetical protein complement(155139..155453) Escherichia coli 536 4189973 YP_668084.2 CDS ECP_0145 NC_008253.1 155557 156426 R hypothetical protein complement(155557..156426) Escherichia coli 536 4189974 YP_668085.1 CDS ECP_0146 NC_008253.1 156452 157048 R protein YadK complement(156452..157048) Escherichia coli 536 4189975 YP_668086.1 CDS ECP_0147 NC_008253.1 157075 157683 R hypothetical protein complement(157075..157683) Escherichia coli 536 4189976 YP_668087.1 CDS ECP_0148 NC_008253.1 157695 158261 R hypothetical protein complement(157695..158261) Escherichia coli 536 4189977 YP_668088.1 CDS ECP_0149 NC_008253.1 158278 160866 R heat shock protein E; similar to the fimbrial usher protein PapC; outer membrane usher protein complement(158278..160866) Escherichia coli 536 4189978 YP_668089.1 CDS ECP_0150 NC_008253.1 160901 161641 R chaperone protein EcpD complement(160901..161641) Escherichia coli 536 4189979 YP_668090.1 CDS ECP_0151 NC_008253.1 161750 162340 R fimbrial-like protein YadN complement(161750..162340) Escherichia coli 536 4189980 YP_668091.1 CDS ECP_0152 NC_008253.1 162702 163181 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(162702..163181) Escherichia coli 536 4189981 YP_668092.1 CDS pcnB NC_008253.1 163178 164596 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase complement(163178..164596) Escherichia coli 536 4188992 YP_668093.2 CDS ECP_0154 NC_008253.1 164635 165531 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(164635..165531) Escherichia coli 536 4188993 YP_668094.1 CDS ECP_0155 NC_008253.1 165598 166053 R DnaK transcriptional regulator DksA complement(165598..166053) Escherichia coli 536 4188994 YP_668095.1 CDS ECP_0156 NC_008253.1 166231 166935 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(166231..166935) Escherichia coli 536 4188995 YP_668096.1 CDS ECP_0157 NC_008253.1 166950 167489 R 2'-5' RNA ligase complement(166950..167489) Escherichia coli 536 4188996 YP_668097.1 CDS ECP_0158 NC_008253.1 167554 169983 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 167554..169983 Escherichia coli 536 4188997 YP_668098.1 CDS mrcB NC_008253.1 170077 172611 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 170077..172611 Escherichia coli 536 4188998 YP_668099.1 CDS ECP_0160 NC_008253.1 172831 175074 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 172831..175074 Escherichia coli 536 4188999 YP_668100.1 CDS ECP_0161 NC_008253.1 175125 175922 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 175125..175922 Escherichia coli 536 4189000 YP_668101.1 CDS ECP_0162 NC_008253.1 175922 176812 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 175922..176812 Escherichia coli 536 4189001 YP_668102.1 CDS ECP_0163 NC_008253.1 176809 178791 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 176809..178791 Escherichia coli 536 4189002 YP_668103.1 CDS ECP_0164 NC_008253.1 178826 180106 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(178826..180106) Escherichia coli 536 4189003 YP_668104.1 CDS ECP_0165 NC_008253.1 180331 181752 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 180331..181752 Escherichia coli 536 4189004 YP_668105.1 CDS ECP_0166 NC_008253.1 181834 182178 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 181834..182178 Escherichia coli 536 4189005 YP_668106.1 CDS ECP_0167 NC_008253.1 182225 182848 R hypothetical protein complement(182225..182848) Escherichia coli 536 4189006 YP_668107.1 CDS ECP_0168 NC_008253.1 183071 183688 R periplasmic binding protein complement(183071..183688) Escherichia coli 536 4189007 YP_668108.1 CDS ECP_0169 NC_008253.1 183681 184379 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(183681..184379) Escherichia coli 536 4189008 YP_668109.1 CDS dgt NC_008253.1 184463 185980 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 184463..185980 Escherichia coli 536 4189009 YP_668110.1 CDS ECP_0171 NC_008253.1 186110 187534 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 186110..187534 Escherichia coli 536 4189010 YP_668111.1 CDS ECP_0172 NC_008253.1 187689 188846 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 187689..188846 Escherichia coli 536 4189011 YP_668112.1 CDS ECP_0173 NC_008253.1 188900 189286 R hypothetical protein complement(188900..189286) Escherichia coli 536 4190255 YP_668113.1 CDS dapD NC_008253.1 189596 190420 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(189596..190420) Escherichia coli 536 4190256 YP_668114.1 CDS ECP_0175 NC_008253.1 190451 193123 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(190451..193123) Escherichia coli 536 4190257 YP_668115.1 CDS ECP_0176 NC_008253.1 193185 193979 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(193185..193979) Escherichia coli 536 4190258 YP_668116.1 CDS rpsB NC_008253.1 194347 195072 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 194347..195072 Escherichia coli 536 4190259 YP_668117.1 CDS tsf NC_008253.1 195207 196058 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 195207..196058 Escherichia coli 536 4190260 YP_668118.1 CDS pyrH NC_008253.1 196205 196930 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 196205..196930 Escherichia coli 536 4190261 YP_668119.1 CDS frr NC_008253.1 197080 197637 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 197080..197637 Escherichia coli 536 4190262 YP_668120.1 CDS ECP_0181 NC_008253.1 197729 198925 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 197729..198925 Escherichia coli 536 4190263 YP_668121.1 CDS ECP_0182 NC_008253.1 199111 199872 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 199111..199872 Escherichia coli 536 4190264 YP_668122.1 CDS cdsA NC_008253.1 199885 200742 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 199885..200742 Escherichia coli 536 4190265 YP_668123.1 CDS ECP_0184 NC_008253.1 200754 202106 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 200754..202106 Escherichia coli 536 4190266 YP_668124.1 CDS ECP_0185 NC_008253.1 202136 204568 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 202136..204568 Escherichia coli 536 4190267 YP_668125.1 CDS ECP_0186 NC_008253.1 204690 205175 D periplasmic chaperone 204690..205175 Escherichia coli 536 4190268 YP_668126.1 CDS lpxD NC_008253.1 205179 206204 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 205179..206204 Escherichia coli 536 4190269 YP_668127.1 CDS fabZ NC_008253.1 206309 206764 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 206309..206764 Escherichia coli 536 4190270 YP_668128.1 CDS ECP_0189 NC_008253.1 206768 207556 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 206768..207556 Escherichia coli 536 4190271 YP_668129.1 CDS lpxB NC_008253.1 207556 208704 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 207556..208704 Escherichia coli 536 4190272 YP_668130.1 CDS rnhB NC_008253.1 208701 209297 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 208701..209297 Escherichia coli 536 4190273 YP_668131.1 CDS dnaE NC_008253.1 209334 212816 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 209334..212816 Escherichia coli 536 4191936 YP_668132.1 CDS ECP_0193 NC_008253.1 212829 213788 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 212829..213788 Escherichia coli 536 4191937 YP_668133.1 CDS ECP_0194 NC_008253.1 213886 216027 D lysine decarboxylase, constitutive 213886..216027 Escherichia coli 536 4191938 YP_668134.1 CDS ECP_0195 NC_008253.1 216084 216473 D hypothetical protein 216084..216473 Escherichia coli 536 4191939 YP_668135.1 CDS tilS NC_008253.1 216538 217851 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 216538..217851 Escherichia coli 536 4191940 YP_668136.1 CDS ECP_0197 NC_008253.1 217885 218145 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(217885..218145) Escherichia coli 536 4191941 YP_668137.1 CDS ECP_0198 NC_008253.1 218132 218332 R hypothetical protein complement(218132..218332) Escherichia coli 536 4191942 YP_668138.1 CDS ECP_0199 NC_008253.1 218498 219043 D hypothetical protein 218498..219043 Escherichia coli 536 4191943 YP_668139.1 CDS ECP_0200 NC_008253.1 219040 219462 D peptidyl-tRNA hydrolase domain-containing protein 219040..219462 Escherichia coli 536 4191944 YP_668140.1 CDS ECP_0201 NC_008253.1 219476 220186 D lipoprotein involved with copper homeostasis and adhesion 219476..220186 Escherichia coli 536 4191945 YP_668141.1 CDS ECP_0202 NC_008253.1 220342 220896 R hypothetical protein complement(220342..220896) Escherichia coli 536 4191946 YP_668142.1 CDS ECP_0203 NC_008253.1 220893 221165 R hypothetical protein complement(220893..221165) Escherichia coli 536 4191947 YP_668143.1 CDS ECP_0204 NC_008253.1 221218 222936 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(221218..222936) Escherichia coli 536 4191948 YP_668144.1 CDS ECP_0205 NC_008253.1 223047 223754 R hypothetical protein complement(223047..223754) Escherichia coli 536 4191949 YP_668145.1 CDS rcsF NC_008253.1 223751 224155 R outer membrane lipoprotein complement(223751..224155) Escherichia coli 536 4191950 YP_668146.1 CDS metQ NC_008253.1 224273 225088 R DL-methionine transporter substrate-binding subunit complement(224273..225088) Escherichia coli 536 4191951 YP_668147.1 CDS ECP_0208 NC_008253.1 225128 225781 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(225128..225781) Escherichia coli 536 4191952 YP_668148.1 CDS metN NC_008253.1 225774 226805 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(225774..226805) Escherichia coli 536 4191953 YP_668149.1 CDS ECP_0210 NC_008253.1 226993 227565 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 226993..227565 Escherichia coli 536 4191954 YP_668150.1 CDS dkgB NC_008253.1 233235 234038 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 233235..234038 Escherichia coli 536 4187363 YP_668151.1 CDS ECP_0214 NC_008253.1 234035 234949 R LysR family transcriptional regulator complement(234035..234949) Escherichia coli 536 4187364 YP_668152.1 CDS ECP_0215 NC_008253.1 235166 235990 D hypothetical protein 235166..235990 Escherichia coli 536 4187365 YP_668153.1 CDS ECP_0216 NC_008253.1 236068 236838 D methyltransferase YafE 236068..236838 Escherichia coli 536 4187366 YP_668154.1 CDS mltD NC_008253.1 236887 238245 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(236887..238245) Escherichia coli 536 4187367 YP_668155.1 CDS ECP_0218 NC_008253.1 238317 239072 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(238317..239072) Escherichia coli 536 4187368 YP_668156.1 CDS ECP_0219 NC_008253.1 239103 239828 D hypothetical protein 239103..239828 Escherichia coli 536 4187369 YP_668157.1 CDS rnhA NC_008253.1 239825 240292 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(239825..240292) Escherichia coli 536 4187370 YP_668158.1 CDS ECP_0221 NC_008253.1 240348 241088 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 240348..241088 Escherichia coli 536 4187371 YP_668159.1 CDS ECP_0223 NC_008253.1 241626 242411 D lipoprotein 241626..242411 Escherichia coli 536 4187373 YP_668160.1 CDS ECP_0224 NC_008253.1 242751 243251 R hypothetical protein complement(242751..243251) Escherichia coli 536 4187374 YP_668161.1 CDS ECP_0225 NC_008253.1 243248 244606 R hypothetical protein complement(243248..244606) Escherichia coli 536 4187375 YP_668162.1 CDS ECP_0226 NC_008253.1 244617 248144 R IcmF-like protein complement(244617..248144) Escherichia coli 536 4187376 YP_668163.1 CDS ECP_0227 NC_008253.1 248164 249672 R hypothetical protein complement(248164..249672) Escherichia coli 536 4187377 YP_668164.1 CDS ECP_0228 NC_008253.1 249611 250354 R hypothetical protein complement(249611..250354) Escherichia coli 536 4187812 YP_668165.1 CDS ECP_0229 NC_008253.1 250351 253113 R Clp ATPase complement(250351..253113) Escherichia coli 536 4187813 YP_668166.1 CDS ECP_0230 NC_008253.1 253123 253887 R hypothetical protein complement(253123..253887) Escherichia coli 536 4187814 YP_668167.1 CDS ECP_0231 NC_008253.1 253892 255238 R hypothetical protein complement(253892..255238) Escherichia coli 536 4187815 YP_668168.1 CDS ECP_0232 NC_008253.1 255241 255765 R lipoprotein complement(255241..255765) Escherichia coli 536 4187816 YP_668169.1 CDS ECP_0233 NC_008253.1 255762 257150 R hypothetical protein complement(255762..257150) Escherichia coli 536 4187817 YP_668170.1 CDS ECP_0234 NC_008253.1 257059 258108 R hypothetical protein complement(257059..258108) Escherichia coli 536 4187818 YP_668171.1 CDS ECP_0235 NC_008253.1 258072 259922 R hypothetical protein complement(258072..259922) Escherichia coli 536 4187819 YP_668172.1 CDS ECP_0236 NC_008253.1 259919 260344 R hypothetical protein complement(259919..260344) Escherichia coli 536 4187820 YP_668173.1 CDS ECP_0237 NC_008253.1 260349 261833 R hypothetical protein complement(260349..261833) Escherichia coli 536 4187821 YP_668174.1 CDS ECP_0238 NC_008253.1 261856 262359 R hypothetical protein complement(261856..262359) Escherichia coli 536 4187822 YP_668175.1 CDS ECP_0239 NC_008253.1 263065 263583 D hemolysin co-regulated protein 263065..263583 Escherichia coli 536 4187823 YP_668176.1 CDS ECP_0240 NC_008253.1 263804 265786 D Vgr-like protein 263804..265786 Escherichia coli 536 4187824 YP_668177.1 CDS ECP_0241 NC_008253.1 265893 266939 D hypothetical protein 265893..266939 Escherichia coli 536 4187825 YP_668178.1 CDS ECP_0242 NC_008253.1 266932 268371 D hypothetical protein 266932..268371 Escherichia coli 536 4187826 YP_668179.1 CDS ECP_0243 NC_008253.1 268346 268636 D hypothetical protein 268346..268636 Escherichia coli 536 4187827 YP_668180.1 CDS ECP_0244 NC_008253.1 268894 269073 D H repeat-containing Rhs element protein 268894..269073 Escherichia coli 536 4187828 YP_668181.1 CDS ECP_0246 NC_008253.1 269350 269658 D H repeat-containing Rhs element protein 269350..269658 Escherichia coli 536 4187830 YP_668182.1 CDS ECP_0247 NC_008253.1 269887 270390 D hypothetical protein 269887..270390 Escherichia coli 536 4190615 YP_668183.1 CDS ECP_0248 NC_008253.1 270484 270972 D hypothetical protein 270484..270972 Escherichia coli 536 4190616 YP_668184.1 CDS ECP_0249 NC_008253.1 271243 272013 R hypothetical protein complement(271243..272013) Escherichia coli 536 4190617 YP_668185.1 CDS ECP_0250 NC_008253.1 272167 272640 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 272167..272640 Escherichia coli 536 4190618 YP_668186.1 CDS fadE NC_008253.1 272683 275127 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(272683..275127) Escherichia coli 536 4190619 YP_668187.1 CDS gmhA NC_008253.1 275367 275945 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 275367..275945 Escherichia coli 536 4190620 YP_668188.1 CDS ECP_0253 NC_008253.1 276150 276917 D glutamine amidotransferase 276150..276917 Escherichia coli 536 4190621 YP_668189.1 CDS ECP_0254 NC_008253.1 276888 277628 R hypothetical protein complement(276888..277628) Escherichia coli 536 4190622 YP_668190.1 CDS ECP_0255 NC_008253.1 277931 278689 D lipoprotein 277931..278689 Escherichia coli 536 4190623 YP_668191.1 CDS ECP_0256 NC_008253.1 278865 279362 D hypothetical protein 278865..279362 Escherichia coli 536 4190624 YP_668192.1 CDS ECP_0257 NC_008253.1 279445 279654 R hypothetical protein complement(279445..279654) Escherichia coli 536 4190625 YP_668193.1 CDS ECP_0258 NC_008253.1 279682 281421 R flagellar biosynthetic protein FlhA complement(279682..281421) Escherichia coli 536 4190626 YP_668194.1 CDS ECP_0259 NC_008253.1 281381 282151 D hypothetical protein 281381..282151 Escherichia coli 536 4190627 YP_668195.1 CDS ECP_0260 NC_008253.1 282222 283277 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 282222..283277 Escherichia coli 536 4190628 YP_668196.1 CDS ECP_0261 NC_008253.1 283329 283622 D antitoxin of the YafO-YafN toxin-antitoxin system 283329..283622 Escherichia coli 536 4190629 YP_668197.1 CDS ECP_0262 NC_008253.1 283625 284023 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 283625..284023 Escherichia coli 536 4190630 YP_668198.1 CDS ECP_0263 NC_008253.1 284033 284485 D hypothetical protein 284033..284485 Escherichia coli 536 4190631 YP_668199.1 CDS ECP_0264 NC_008253.1 284663 285814 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 284663..285814 Escherichia coli 536 4190632 YP_668200.2 CDS prfH NC_008253.1 285925 286425 D similar to release factor 1 and 2; peptide chain release factor-like protein 285925..286425 Escherichia coli 536 4190633 YP_668201.1 CDS ECP_0266 NC_008253.1 286482 287939 R aminoacyl-histidine dipeptidase complement(286482..287939) Escherichia coli 536 4190158 YP_668202.1 CDS ECP_0267 NC_008253.1 288200 288658 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 288200..288658 Escherichia coli 536 4190159 YP_668203.1 CDS frsA NC_008253.1 288750 289994 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 288750..289994 Escherichia coli 536 4190160 YP_668204.1 CDS ECP_0269 NC_008253.1 290052 290453 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 290052..290453 Escherichia coli 536 4190161 YP_668205.1 CDS ECP_0270 NC_008253.1 290492 291547 R outer membrane phosphoporin protein E complement(290492..291547) Escherichia coli 536 4190162 YP_668206.1 CDS ECP_0271 NC_008253.1 291836 292939 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 291836..292939 Escherichia coli 536 4190163 YP_668207.1 CDS proA NC_008253.1 292951 294204 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 292951..294204 Escherichia coli 536 4190164 YP_668208.1 CDS ECP_0274 NC_008253.1 294409 295569 R phage integrase complement(294409..295569) Escherichia coli 536 4190166 YP_668209.1 CDS ECP_0275 NC_008253.1 295883 296227 R hypothetical protein complement(295883..296227) Escherichia coli 536 4190167 YP_668210.1 CDS ECP_0276 NC_008253.1 296525 297547 D transposase for insertion sequence IS100 296525..297547 Escherichia coli 536 4190168 YP_668211.1 CDS ECP_0277 NC_008253.1 297547 298326 D transposase/IS protein 297547..298326 Escherichia coli 536 4190169 YP_668212.1 CDS ECP_0278 NC_008253.1 298377 300128 R hypothetical protein complement(298377..300128) Escherichia coli 536 4190170 YP_668213.1 CDS ECP_0279 NC_008253.1 300321 300704 R transposase complement(300321..300704) Escherichia coli 536 4190171 YP_668214.1 CDS ECP_0280 NC_008253.1 301428 301625 D hypothetical protein 301428..301625 Escherichia coli 536 4190172 YP_668215.1 CDS ECP_0281 NC_008253.1 301649 302683 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose-4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 301649..302683 Escherichia coli 536 4190173 YP_668216.1 CDS ECP_0282 NC_008253.1 302813 302992 D hypothetical protein 302813..302992 Escherichia coli 536 4190174 YP_668217.1 CDS ECP_0283 NC_008253.1 303560 304414 R transposase complement(303560..304414) Escherichia coli 536 4190175 YP_668218.1 CDS ECP_0284 NC_008253.1 304411 304710 R transposase complement(304411..304710) Escherichia coli 536 4190176 YP_668219.1 CDS ECP_0285 NC_008253.1 304806 305861 D ABC transporter ATP-binding protein 304806..305861 Escherichia coli 536 4187528 YP_668220.1 CDS ECP_0286 NC_008253.1 306132 306464 D hypothetical protein 306132..306464 Escherichia coli 536 4187529 YP_668221.1 CDS ECP_0287 NC_008253.1 306641 307327 R hypothetical protein complement(306641..307327) Escherichia coli 536 4187530 YP_668222.1 CDS ECP_0288 NC_008253.1 307422 307892 R hypothetical protein complement(307422..307892) Escherichia coli 536 4187531 YP_668223.1 CDS ECP_0289 NC_008253.1 308401 308850 D hypothetical protein 308401..308850 Escherichia coli 536 4187532 YP_668224.1 CDS ECP_0290 NC_008253.1 309092 309661 D hypothetical protein 309092..309661 Escherichia coli 536 4187533 YP_668225.1 CDS ECP_0291 NC_008253.1 309936 310157 R fimbrial transcription regulator protein FaeA complement(309936..310157) Escherichia coli 536 4187534 YP_668226.1 CDS ECP_0292 NC_008253.1 310576 310905 D major pilu subunit operon regulatory protein PapB 310576..310905 Escherichia coli 536 4187535 YP_668227.1 CDS ECP_0293 NC_008253.1 311279 311824 D S-fimbrial protein subunit 311279..311824 Escherichia coli 536 4187536 YP_668228.1 CDS ECP_0294 NC_008253.1 311895 312434 D minor F1C fimbrial subunit 311895..312434 Escherichia coli 536 4187537 YP_668229.1 CDS ECP_0295 NC_008253.1 312475 313170 D F1C periplasmic chaperone 312475..313170 Escherichia coli 536 4187538 YP_668230.1 CDS ECP_0296 NC_008253.1 313241 315871 D F1C fimbrial usher 313241..315871 Escherichia coli 536 4187539 YP_668231.1 CDS ECP_0297 NC_008253.1 315887 316411 D F1C minor fimbrial subunit F 315887..316411 Escherichia coli 536 4187540 YP_668232.1 CDS ECP_0298 NC_008253.1 316433 316924 D F1C minor fimbrial subunit protein G presursor 316433..316924 Escherichia coli 536 4187541 YP_668233.1 CDS ECP_0299 NC_008253.1 316986 317885 D F1C fimbrial adhesin 316986..317885 Escherichia coli 536 4187542 YP_668234.1 CDS ECP_0300 NC_008253.1 318189 318929 D hypothetical protein 318189..318929 Escherichia coli 536 4187543 YP_668235.1 CDS ECP_0301 NC_008253.1 319076 319627 D MarR family transcriptional regulator 319076..319627 Escherichia coli 536 4187544 YP_668236.1 CDS ECP_0302 NC_008253.1 320121 322298 D Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 320121..322298 Escherichia coli 536 4187545 YP_668237.1 CDS ECP_0303 NC_008253.1 322343 323299 R IroE protein complement(322343..323299) Escherichia coli 536 4187546 YP_668238.1 CDS ECP_0304 NC_008253.1 323384 324613 R esterase complement(323384..324613) Escherichia coli 536 4190518 YP_668239.1 CDS ECP_0305 NC_008253.1 324717 328454 R ABC transporter complement(324717..328454) Escherichia coli 536 4190519 YP_668240.1 CDS ECP_0306 NC_008253.1 328516 329631 R glycosyl transferase family protein complement(328516..329631) Escherichia coli 536 4190520 YP_668241.1 CDS ECP_0307 NC_008253.1 330169 330468 D hypothetical protein 330169..330468 Escherichia coli 536 4190521 YP_668242.1 CDS ECP_0308 NC_008253.1 330479 330838 R transposase InsG for insertion sequence element IS4 complement(330479..330838) Escherichia coli 536 4190522 YP_668243.1 CDS ECP_0309 NC_008253.1 331753 332031 D hypothetical protein 331753..332031 Escherichia coli 536 4190523 YP_668244.1 CDS ECP_0311 NC_008253.1 332752 333210 R transposase complement(332752..333210) Escherichia coli 536 4190525 YP_668245.1 CDS ECP_0312 NC_008253.1 333222 334031 R hypothetical protein complement(333222..334031) Escherichia coli 536 4190526 YP_668246.1 CDS ECP_0313 NC_008253.1 334157 334375 D hypothetical protein 334157..334375 Escherichia coli 536 4190527 YP_668247.1 CDS ECP_0314 NC_008253.1 334467 336431 D TonB-dependent receptor 334467..336431 Escherichia coli 536 4190528 YP_668248.1 CDS ECP_0315 NC_008253.1 336450 337241 D hypothetical protein 336450..337241 Escherichia coli 536 4190529 YP_668249.1 CDS ECP_0316 NC_008253.1 337442 338704 D cobalamin synthesis protein 337442..338704 Escherichia coli 536 4190530 YP_668250.1 CDS ECP_0317 NC_008253.1 338889 339026 D hypothetical protein 338889..339026 Escherichia coli 536 4190531 YP_668251.1 CDS ECP_0318 NC_008253.1 339159 339758 D transposase for insertion sequence IS100 339159..339758 Escherichia coli 536 4190532 YP_668252.1 CDS ECP_0319 NC_008253.1 339758 340537 D transposase/IS protein 339758..340537 Escherichia coli 536 4190533 YP_668253.1 CDS ECP_0320 NC_008253.1 340588 341205 R IS orf complement(340588..341205) Escherichia coli 536 4190534 YP_668254.1 CDS ECP_0321 NC_008253.1 341225 341572 R transposase complement(341225..341572) Escherichia coli 536 4190535 YP_668255.1 CDS ECP_0322 NC_008253.1 341569 341931 R IS orf complement(341569..341931) Escherichia coli 536 4190536 YP_668256.1 CDS ECP_0323 NC_008253.1 342066 342251 R hypothetical protein complement(342066..342251) Escherichia coli 536 4187983 YP_668257.1 CDS ECP_0324 NC_008253.1 342718 343605 R specific inhibitor of chromosomal initiation of replication in vitro; inds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein complement(342718..343605) Escherichia coli 536 4187984 YP_668258.1 CDS ECP_0325 NC_008253.1 343652 345148 R lysyl-tRNA synthetase complement(343652..345148) Escherichia coli 536 4187985 YP_668259.1 CDS ECP_0326 NC_008253.1 345442 346164 R AraC family transcriptional regulator complement(345442..346164) Escherichia coli 536 4187986 YP_668260.1 CDS ECP_0327 NC_008253.1 346356 348482 R lysine decarboxylase complement(346356..348482) Escherichia coli 536 4187987 YP_668261.1 CDS cadB NC_008253.1 348513 349823 R probable cadaverine/lysine antiporter; antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(348513..349823) Escherichia coli 536 4187988 YP_668262.1 CDS ECP_0329 NC_008253.1 350210 350572 D IS orf 350210..350572 Escherichia coli 536 4187989 YP_668263.1 CDS ECP_0330 NC_008253.1 350873 351055 R hypothetical protein complement(350873..351055) Escherichia coli 536 4187990 YP_668264.1 CDS ECP_0331 NC_008253.1 351386 352258 D hypothetical protein 351386..352258 Escherichia coli 536 4187991 YP_668265.1 CDS ECP_0332 NC_008253.1 352586 355714 D autotransporter 352586..355714 Escherichia coli 536 4187992 YP_668266.1 CDS ECP_0333 NC_008253.1 356041 356859 D hypothetical protein 356041..356859 Escherichia coli 536 4187993 YP_668267.1 CDS ECP_0334 NC_008253.1 356951 357436 D anti-restriction protein 356951..357436 Escherichia coli 536 4187994 YP_668268.1 CDS ECP_0335 NC_008253.1 357452 357928 D RadC-like DNA repair protein 357452..357928 Escherichia coli 536 4187995 YP_668269.1 CDS ECP_0336 NC_008253.1 357997 358218 D hypothetical protein 357997..358218 Escherichia coli 536 4187996 YP_668270.1 CDS ECP_0337 NC_008253.1 358381 358749 D hypothetical protein 358381..358749 Escherichia coli 536 4187997 YP_668271.1 CDS ECP_0338 NC_008253.1 358839 359216 D hypothetical protein 358839..359216 Escherichia coli 536 4187998 YP_668272.1 CDS ECP_0339 NC_008253.1 359213 359701 D hypothetical protein 359213..359701 Escherichia coli 536 4187999 YP_668273.1 CDS ECP_0340 NC_008253.1 359668 359910 D hypothetical protein 359668..359910 Escherichia coli 536 4188000 YP_668274.1 CDS ECP_0341 NC_008253.1 360025 360849 D hypothetical protein 360025..360849 Escherichia coli 536 4188001 YP_668275.1 CDS ECP_0342 NC_008253.1 360942 362261 R phage integrase complement(360942..362261) Escherichia coli 536 4190693 YP_668276.1 CDS ECP_0343 NC_008253.1 362627 362965 D CP4-like integrase 362627..362965 Escherichia coli 536 4190694 YP_668277.1 CDS ECP_0344 NC_008253.1 363400 363924 R MarR family transcriptional regulator complement(363400..363924) Escherichia coli 536 4190695 YP_668278.1 CDS ECP_0345 NC_008253.1 364050 368180 R extracellular serine protease of the IgA1 protease, secreted by a C-terminal autotransporter domain; protein SepA complement(364050..368180) Escherichia coli 536 4190696 YP_668279.1 CDS ECP_0346 NC_008253.1 368508 368711 R hypothetical protein complement(368508..368711) Escherichia coli 536 4190697 YP_668280.1 CDS ECP_0347 NC_008253.1 368773 368988 D insertion element IS1 1/2/3/5/6 protein InsA 368773..368988 Escherichia coli 536 4190698 YP_668281.1 CDS ECP_0348 NC_008253.1 369290 369466 D InsB protein 369290..369466 Escherichia coli 536 4190699 YP_668282.1 CDS ECP_0349 NC_008253.1 369890 370075 D hypothetical protein 369890..370075 Escherichia coli 536 4190700 YP_668283.1 CDS ECP_0350 NC_008253.1 370290 370904 D integral membrane protein 370290..370904 Escherichia coli 536 4190701 YP_668284.1 CDS ECP_0351 NC_008253.1 371153 371482 R ferredoxin complement(371153..371482) Escherichia coli 536 4190702 YP_668285.1 CDS ECP_0352 NC_008253.1 371789 372499 R hypothetical protein complement(371789..372499) Escherichia coli 536 4190703 YP_668286.1 CDS ECP_0353 NC_008253.1 372468 374111 R hypothetical protein complement(372468..374111) Escherichia coli 536 4190704 YP_668287.1 CDS ECP_0354 NC_008253.1 374101 376626 R hypothetical protein complement(374101..376626) Escherichia coli 536 4190705 YP_668288.1 CDS ECP_0355 NC_008253.1 376652 377368 R hypothetical protein complement(376652..377368) Escherichia coli 536 4190706 YP_668289.1 CDS ECP_0356 NC_008253.1 377377 377964 R hypothetical protein complement(377377..377964) Escherichia coli 536 4190707 YP_668290.1 CDS ECP_0357 NC_008253.1 378039 378581 R hypothetical protein complement(378039..378581) Escherichia coli 536 4190708 YP_668291.1 CDS ECP_0358 NC_008253.1 379053 379343 D hypothetical protein 379053..379343 Escherichia coli 536 4190709 YP_668292.1 CDS rpmJ NC_008253.1 379665 379805 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(379665..379805) Escherichia coli 536 4190710 YP_668293.1 CDS rpmE2 NC_008253.1 379805 380071 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(379805..380071) Escherichia coli 536 4190711 YP_668294.1 CDS ECP_0361 NC_008253.1 381007 382149 R NADH-dependent flavin oxidoreductase complement(381007..382149) Escherichia coli 536 4190712 YP_668295.1 CDS ECP_0362 NC_008253.1 382321 383241 R hypothetical protein complement(382321..383241) Escherichia coli 536 4191131 YP_668296.1 CDS ECP_0363 NC_008253.1 383398 384324 D LysR family transcriptional regulator 383398..384324 Escherichia coli 536 4191132 YP_668297.1 CDS ECP_0364 NC_008253.1 384524 385417 D LysR family transcriptional regulator 384524..385417 Escherichia coli 536 4191133 YP_668298.1 CDS ECP_0365 NC_008253.1 385448 386437 R aldo/keto reductase complement(385448..386437) Escherichia coli 536 4191134 YP_668299.1 CDS ECP_0366 NC_008253.1 386464 387315 R aldo/keto reductase complement(386464..387315) Escherichia coli 536 4191135 YP_668300.1 CDS ECP_0367 NC_008253.1 387881 392128 D adhesin/invasin 387881..392128 Escherichia coli 536 4191136 YP_668301.1 CDS ECP_0368 NC_008253.1 392253 393110 R AraC family transcriptional regulator complement(392253..393110) Escherichia coli 536 4191137 YP_668302.1 CDS ECP_0369 NC_008253.1 393358 394227 D aldo/keto reductase 393358..394227 Escherichia coli 536 4191138 YP_668303.1 CDS ECP_0370 NC_008253.1 394387 394980 R hypothetical protein complement(394387..394980) Escherichia coli 536 4191139 YP_668304.1 CDS ECP_0371 NC_008253.1 394992 395228 R hypothetical protein complement(394992..395228) Escherichia coli 536 4191140 YP_668305.1 CDS ECP_0372 NC_008253.1 395337 396662 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(395337..396662) Escherichia coli 536 4191141 YP_668306.1 CDS ECP_0373 NC_008253.1 396889 397743 D AraC family transcriptional regulator 396889..397743 Escherichia coli 536 4191142 YP_668307.1 CDS ECP_0374 NC_008253.1 398270 398989 D hypothetical protein 398270..398989 Escherichia coli 536 4191143 YP_668308.1 CDS ECP_0375 NC_008253.1 399000 400427 D electron transport protein YkgF 399000..400427 Escherichia coli 536 4191144 YP_668309.1 CDS ECP_0376 NC_008253.1 400420 401115 D hypothetical protein 400420..401115 Escherichia coli 536 4191145 YP_668310.1 CDS ECP_0377 NC_008253.1 401189 401386 R hypothetical protein complement(401189..401386) Escherichia coli 536 4191146 YP_668311.1 CDS ECP_0378 NC_008253.1 401358 402026 R hypothetical protein complement(401358..402026) Escherichia coli 536 4191147 YP_668312.1 CDS ECP_0379 NC_008253.1 402210 404507 R autotransporter complement(402210..404507) Escherichia coli 536 4191148 YP_668313.1 CDS ECP_0380 NC_008253.1 404549 405310 R hypothetical protein complement(404549..405310) Escherichia coli 536 4191149 YP_668314.1 CDS ECP_0381 NC_008253.1 405464 406258 R hypothetical protein complement(405464..406258) Escherichia coli 536 4191034 YP_668315.1 CDS ECP_0382 NC_008253.1 406588 407151 R phage integrase complement(406588..407151) Escherichia coli 536 4191035 YP_668316.1 CDS ECP_0383 NC_008253.1 407041 407247 D hypothetical protein 407041..407247 Escherichia coli 536 4191036 YP_668317.1 CDS ECP_0384 NC_008253.1 407257 407511 D hypothetical protein 407257..407511 Escherichia coli 536 4191037 YP_668318.1 CDS ECP_0385 NC_008253.1 407967 408194 D hypothetical protein 407967..408194 Escherichia coli 536 4191038 YP_668319.2 CDS ECP_0386 NC_008253.1 408236 409906 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(408236..409906) Escherichia coli 536 4191039 YP_668320.1 CDS ECP_0387 NC_008253.1 409920 411392 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(409920..411392) Escherichia coli 536 4191040 YP_668321.1 CDS ECP_0388 NC_008253.1 411406 412011 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(411406..412011) Escherichia coli 536 4191041 YP_668322.1 CDS ECP_0389 NC_008253.1 411910 412125 D hypothetical protein 411910..412125 Escherichia coli 536 4191042 YP_668323.1 CDS ECP_0390 NC_008253.1 412122 414155 D proton-motive-force-driven choline transporter; choline transport protein BetT 412122..414155 Escherichia coli 536 4191043 YP_668324.1 CDS ECP_0391 NC_008253.1 415031 416119 D hypothetical protein 415031..416119 Escherichia coli 536 4191044 YP_668325.1 CDS ECP_0392 NC_008253.1 416161 417093 R transcriptional regulator YahB complement(416161..417093) Escherichia coli 536 4191045 YP_668326.1 CDS ECP_0393 NC_008253.1 417185 417682 R hypothetical protein complement(417185..417682) Escherichia coli 536 4191046 YP_668327.1 CDS ECP_0394 NC_008253.1 417759 418001 D hypothetical protein 417759..418001 Escherichia coli 536 4191047 YP_668328.1 CDS ECP_0395 NC_008253.1 417940 418545 D ankyrin repeat-containing protein 417940..418545 Escherichia coli 536 4191048 YP_668329.1 CDS ECP_0396 NC_008253.1 418585 419448 D hypothetical protein 418585..419448 Escherichia coli 536 4191049 YP_668330.1 CDS ECP_0397 NC_008253.1 419438 420985 D YahF/FdrA-like protein 419438..420985 Escherichia coli 536 4191050 YP_668331.1 CDS ECP_0398 NC_008253.1 420985 422403 D hypothetical protein 420985..422403 Escherichia coli 536 4191051 YP_668332.1 CDS ECP_0399 NC_008253.1 422650 423600 D carbamate kinase 422650..423600 Escherichia coli 536 4191052 YP_668333.1 CDS ECP_0400 NC_008253.1 423610 424992 D deaminase 423610..424992 Escherichia coli 536 4191053 YP_668334.1 CDS ECP_0401 NC_008253.1 425369 426418 D zinc-type alcohol dehydrogenase-like protein YahK 425369..426418 Escherichia coli 536 4191762 YP_668335.1 CDS ECP_0402 NC_008253.1 426652 426816 D hypothetical protein 426652..426816 Escherichia coli 536 4191763 YP_668336.1 CDS ECP_0404 NC_008253.1 427300 427974 R LysE family translocator complement(427300..427974) Escherichia coli 536 4191765 YP_668337.1 CDS ECP_0405 NC_008253.1 428121 428396 D hypothetical protein 428121..428396 Escherichia coli 536 4191766 YP_668338.1 CDS ECP_0406 NC_008253.1 428497 430083 R propionate catabolism operon regulatory protein complement(428497..430083) Escherichia coli 536 4191767 YP_668339.1 CDS prpB NC_008253.1 430322 431212 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 430322..431212 Escherichia coli 536 4191768 YP_668340.1 CDS ECP_0408 NC_008253.1 431372 432541 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 431372..432541 Escherichia coli 536 4191769 YP_668341.1 CDS prpD NC_008253.1 432575 434026 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 432575..434026 Escherichia coli 536 4191770 YP_668342.1 CDS prpE NC_008253.1 434066 435952 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 434066..435952 Escherichia coli 536 4191771 YP_668343.1 CDS codB NC_008253.1 436277 437536 D cytosine permease 436277..437536 Escherichia coli 536 4191772 YP_668344.1 CDS ECP_0412 NC_008253.1 437526 438809 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 437526..438809 Escherichia coli 536 4191773 YP_668345.1 CDS ECP_0413 NC_008253.1 438889 439491 R IS transposase complement(438889..439491) Escherichia coli 536 4191774 YP_668346.1 CDS ECP_0414 NC_008253.1 439716 440237 R IS transposase complement(439716..440237) Escherichia coli 536 4191775 YP_668347.1 CDS lacA NC_008253.1 440366 440986 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(440366..440986) Escherichia coli 536 4191776 YP_668348.1 CDS lacY NC_008253.1 441043 442296 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(441043..442296) Escherichia coli 536 4191777 YP_668349.1 CDS lacZ NC_008253.1 442348 445422 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(442348..445422) Escherichia coli 536 4191778 YP_668350.1 CDS lacI NC_008253.1 445545 446627 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(445545..446627) Escherichia coli 536 4191779 YP_668351.1 CDS ECP_0419 NC_008253.1 446829 447368 D hypothetical protein 446829..447368 Escherichia coli 536 4188789 YP_668352.1 CDS ECP_0420 NC_008253.1 447595 448428 R esterase complement(447595..448428) Escherichia coli 536 4188790 YP_668353.1 CDS ECP_0421 NC_008253.1 448521 449630 R glutathione-dependent formaldehyde dehydrogenase complement(448521..449630) Escherichia coli 536 4188791 YP_668354.1 CDS ECP_0422 NC_008253.1 449665 449940 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(449665..449940) Escherichia coli 536 4188792 YP_668355.1 CDS ECP_0423 NC_008253.1 450130 450903 R hypothetical protein complement(450130..450903) Escherichia coli 536 4188793 YP_668356.1 CDS ECP_0424 NC_008253.1 450905 451345 R transferase complement(450905..451345) Escherichia coli 536 4188794 YP_668357.1 CDS ECP_0425 NC_008253.1 451464 452660 R glycosyl transferase family protein complement(451464..452660) Escherichia coli 536 4188795 YP_668358.1 CDS ECP_0426 NC_008253.1 452670 453341 R LmbE-like protein complement(452670..453341) Escherichia coli 536 4188796 YP_668359.1 CDS tauB NC_008253.1 454925 455692 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 454925..455692 Escherichia coli 536 4188799 YP_668360.1 CDS ECP_0430 NC_008253.1 455689 456516 D taurine transporter subunit 455689..456516 Escherichia coli 536 4188800 YP_668361.1 CDS tauD NC_008253.1 456513 457364 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 456513..457364 Escherichia coli 536 4188801 YP_668362.1 CDS ECP_0432 NC_008253.1 457404 458411 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(457404..458411) Escherichia coli 536 4188802 YP_668363.1 CDS ECP_0433 NC_008253.1 458904 461891 D autotransporter/pertactin 458904..461891 Escherichia coli 536 4188803 YP_668364.1 CDS ECP_0434 NC_008253.1 461977 462600 D DNA-binding transcriptional regulator 461977..462600 Escherichia coli 536 4188804 YP_668365.1 CDS ECP_0435 NC_008253.1 462601 463731 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(462601..463731) Escherichia coli 536 4188805 YP_668366.1 CDS ECP_0436 NC_008253.1 464110 465330 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 464110..465330 Escherichia coli 536 4188204 YP_668367.1 CDS ECP_0437 NC_008253.1 465343 466437 D lipoprotein YaiW 465343..466437 Escherichia coli 536 4188205 YP_668368.1 CDS ECP_0438 NC_008253.1 466496 466804 R hypothetical protein complement(466496..466804) Escherichia coli 536 4188206 YP_668369.1 CDS ECP_0439 NC_008253.1 467064 467276 D hypothetical protein 467064..467276 Escherichia coli 536 4188207 YP_668370.1 CDS ddl NC_008253.1 467300 468394 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(467300..468394) Escherichia coli 536 4188208 YP_668371.1 CDS ECP_0441 NC_008253.1 468857 469117 D hypothetical protein 468857..469117 Escherichia coli 536 4188209 YP_668372.1 CDS ECP_0442 NC_008253.1 469218 470633 D alkaline phosphatase 469218..470633 Escherichia coli 536 4188210 YP_668373.1 CDS ECP_0443 NC_008253.1 470752 471072 D hypothetical protein 470752..471072 Escherichia coli 536 4188211 YP_668374.1 CDS adrA NC_008253.1 471174 472289 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 471174..472289 Escherichia coli 536 4188212 YP_668375.1 CDS ECP_0445 NC_008253.1 472306 473115 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(472306..473115) Escherichia coli 536 4188213 YP_668376.1 CDS ECP_0446 NC_008253.1 473235 473693 D hypothetical protein 473235..473693 Escherichia coli 536 4188214 YP_668377.1 CDS aroL NC_008253.1 473876 474400 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 473876..474400 Escherichia coli 536 4188215 YP_668378.1 CDS ECP_0448 NC_008253.1 474450 474641 D hypothetical protein 474450..474641 Escherichia coli 536 4188216 YP_668379.1 CDS ECP_0449 NC_008253.1 474672 474851 D hypothetical protein 474672..474851 Escherichia coli 536 4188217 YP_668380.1 CDS ECP_0450 NC_008253.1 474899 475576 D hypothetical protein 474899..475576 Escherichia coli 536 4188218 YP_668381.1 CDS ECP_0451 NC_008253.1 475648 475932 D hypothetical protein 475648..475932 Escherichia coli 536 4188219 YP_668382.1 CDS ECP_0452 NC_008253.1 476140 476421 D hypothetical protein 476140..476421 Escherichia coli 536 4188220 YP_668383.1 CDS rdgC NC_008253.1 476579 477490 R Required for efficient pilin antigenic variation; recombination associated protein complement(476579..477490) Escherichia coli 536 4188221 YP_668384.1 CDS ECP_0454 NC_008253.1 477615 478523 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 477615..478523 Escherichia coli 536 4188222 YP_668385.1 CDS ECP_0455 NC_008253.1 478792 479976 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(478792..479976) Escherichia coli 536 4188223 YP_668386.1 CDS ECP_0456 NC_008253.1 480102 483245 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC complement(480102..483245) Escherichia coli 536 4188166 YP_668387.1 CDS ECP_0457 NC_008253.1 483242 484468 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD complement(483242..484468) Escherichia coli 536 4188167 YP_668388.1 CDS ECP_0458 NC_008253.1 484634 485365 D phosphate regulon transcriptional regulatory protein PhoB 484634..485365 Escherichia coli 536 4188168 YP_668389.1 CDS phoR NC_008253.1 485380 486675 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 485380..486675 Escherichia coli 536 4188169 YP_668390.1 CDS ECP_0460 NC_008253.1 487082 488401 D branched-chain amino acid permease 487082..488401 Escherichia coli 536 4188170 YP_668391.1 CDS proY NC_008253.1 488477 489850 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 488477..489850 Escherichia coli 536 4188171 YP_668392.1 CDS ECP_0462 NC_008253.1 490006 491823 D maltodextrin glucosidase 490006..491823 Escherichia coli 536 4188172 YP_668393.1 CDS ECP_0463 NC_008253.1 491828 492409 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase complement(491828..492409) Escherichia coli 536 4188173 YP_668394.1 CDS queA NC_008253.1 492502 493572 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 492502..493572 Escherichia coli 536 4188174 YP_668395.1 CDS tgt NC_008253.1 493627 494754 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 493627..494754 Escherichia coli 536 4188175 YP_668396.1 CDS yajC NC_008253.1 494777 495109 D preprotein translocase subunit; member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 494777..495109 Escherichia coli 536 4188176 YP_668397.1 CDS secD NC_008253.1 495137 496984 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 495137..496984 Escherichia coli 536 4188177 YP_668398.1 CDS secF NC_008253.1 496950 497966 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 496950..497966 Escherichia coli 536 4188178 YP_668399.1 CDS ECP_0469 NC_008253.1 498096 498443 D hypothetical protein 498096..498443 Escherichia coli 536 4188179 YP_668400.1 CDS ECP_0470 NC_008253.1 498481 499365 R nucleoside-specific channel-forming protein tsx complement(498481..499365) Escherichia coli 536 4188180 YP_668401.1 CDS ECP_0471 NC_008253.1 499664 500203 R hypothetical protein complement(499664..500203) Escherichia coli 536 4188181 YP_668402.1 CDS nrdR NC_008253.1 500354 500803 D transcriptional regulator NrdR 500354..500803 Escherichia coli 536 4188182 YP_668403.1 CDS ribD NC_008253.1 500825 501910 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 500825..501910 Escherichia coli 536 4188183 YP_668404.1 CDS ribH NC_008253.1 501999 502469 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 501999..502469 Escherichia coli 536 4188184 YP_668405.1 CDS nusB NC_008253.1 502489 502908 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 502489..502908 Escherichia coli 536 4189604 YP_668406.1 CDS ECP_0476 NC_008253.1 502986 503963 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 502986..503963 Escherichia coli 536 4189605 YP_668407.1 CDS ECP_0477 NC_008253.1 503941 504459 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 503941..504459 Escherichia coli 536 4189606 YP_668408.1 CDS ECP_0478 NC_008253.1 504513 505487 R oxidoreductase complement(504513..505487) Escherichia coli 536 4189607 YP_668409.1 CDS ECP_0479 NC_008253.1 505542 507404 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(505542..507404) Escherichia coli 536 4189608 YP_668410.1 CDS ECP_0480 NC_008253.1 507429 508328 R geranyltranstransferase complement(507429..508328) Escherichia coli 536 4189609 YP_668411.1 CDS ECP_0481 NC_008253.1 508328 508570 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(508328..508570) Escherichia coli 536 4189610 YP_668412.1 CDS ECP_0484 NC_008253.1 510279 510719 R 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis; ThiJ protein complement(510279..510719) Escherichia coli 536 4189613 YP_668413.1 CDS ECP_0485 NC_008253.1 510832 511743 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(510832..511743) Escherichia coli 536 4189614 YP_668414.1 CDS ECP_0486 NC_008253.1 511911 512402 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 511911..512402 Escherichia coli 536 4189615 YP_668415.1 CDS ECP_0487 NC_008253.1 512530 513894 R transporter complement(512530..513894) Escherichia coli 536 4189616 YP_668416.1 CDS ECP_0488 NC_008253.1 514043 514933 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(514043..514933) Escherichia coli 536 4189617 YP_668417.1 CDS ECP_0489 NC_008253.1 514945 515274 R cytochrome o ubiquinol oxidase subunit IV complement(514945..515274) Escherichia coli 536 4189618 YP_668418.1 CDS ECP_0490 NC_008253.1 515274 515888 R cytochrome o ubiquinol oxidase subunit III complement(515274..515888) Escherichia coli 536 4189619 YP_668419.1 CDS ECP_0491 NC_008253.1 515878 517869 R cytochrome o ubiquinol oxidase subunit I complement(515878..517869) Escherichia coli 536 4189620 YP_668420.1 CDS ECP_0492 NC_008253.1 517891 518838 R cytochrome o ubiquinol oxidase subunit II complement(517891..518838) Escherichia coli 536 4190041 YP_668421.1 CDS ampG NC_008253.1 519298 520773 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(519298..520773) Escherichia coli 536 4190042 YP_668422.1 CDS ECP_0494 NC_008253.1 520817 521497 R hypothetical protein complement(520817..521497) Escherichia coli 536 4190043 YP_668423.1 CDS ECP_0495 NC_008253.1 521700 522017 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 521700..522017 Escherichia coli 536 4190044 YP_668424.1 CDS ECP_0496 NC_008253.1 522026 522214 D hypothetical protein 522026..522214 Escherichia coli 536 4190045 YP_668425.1 CDS tig NC_008253.1 522361 523659 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 522361..523659 Escherichia coli 536 4190046 YP_668426.1 CDS clpP NC_008253.1 523905 524528 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 523905..524528 Escherichia coli 536 4190047 YP_668427.1 CDS clpX NC_008253.1 524654 525928 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 524654..525928 Escherichia coli 536 4190048 YP_668428.1 CDS ECP_0500 NC_008253.1 526116 528470 D DNA-binding ATP-dependent protease La 526116..528470 Escherichia coli 536 4190049 YP_668429.1 CDS ECP_0501 NC_008253.1 528679 528951 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 528679..528951 Escherichia coli 536 4190050 YP_668430.1 CDS ECP_0502 NC_008253.1 529143 531014 D peptidyl-prolyl cis-trans isomerase 529143..531014 Escherichia coli 536 4190051 YP_668431.1 CDS ECP_0503 NC_008253.1 531165 531536 D hypothetical protein 531165..531536 Escherichia coli 536 4190052 YP_668432.1 CDS ECP_0504 NC_008253.1 531642 532040 D hypothetical protein 531642..532040 Escherichia coli 536 4190053 YP_668433.1 CDS ECP_0505 NC_008253.1 532092 532787 R Queuosine biosynthesis protein queC; YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(532092..532787) Escherichia coli 536 4190054 YP_668434.1 CDS ECP_0506 NC_008253.1 532852 534552 R hypothetical protein YbaE; extracellular solute-binding protein complement(532852..534552) Escherichia coli 536 4190055 YP_668435.1 CDS ECP_0507 NC_008253.1 534652 535470 D haloacid dehalogenase-like hydrolase 534652..535470 Escherichia coli 536 4190056 YP_668436.1 CDS ECP_0508 NC_008253.1 535539 536081 D AsnC family transcriptional regulator 535539..536081 Escherichia coli 536 4190057 YP_668437.1 CDS ECP_0509 NC_008253.1 536111 537883 D multidrug transporter membrane\ATP-binding components 536111..537883 Escherichia coli 536 4190058 YP_668438.1 CDS ECP_0510 NC_008253.1 537876 539657 D multidrug transporter membrane\ATP-binding components 537876..539657 Escherichia coli 536 4190059 YP_668439.1 CDS ECP_0511 NC_008253.1 539838 540176 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 539838..540176 Escherichia coli 536 4190060 YP_668440.1 CDS ECP_0512 NC_008253.1 540206 541492 D ammonium transporter 540206..541492 Escherichia coli 536 4188113 YP_668441.1 CDS ECP_0513 NC_008253.1 541541 542401 R acyl-CoA thioesterase complement(541541..542401) Escherichia coli 536 4188114 YP_668442.1 CDS ECP_0514 NC_008253.1 542619 543053 D similar to N-terminal part of lipoprotein YbaY; hypothetical protein 542619..543053 Escherichia coli 536 4188115 YP_668443.1 CDS ECP_0515 NC_008253.1 543070 543192 D hypothetical protein 543070..543192 Escherichia coli 536 4188116 YP_668444.1 CDS ECP_0516 NC_008253.1 543223 543534 R methyltransferase complement(543223..543534) Escherichia coli 536 4188117 YP_668445.1 CDS ECP_0517 NC_008253.1 543913 544266 D hypothetical protein 543913..544266 Escherichia coli 536 4188118 YP_668446.1 CDS ECP_0518 NC_008253.1 544308 545858 R hypothetical protein YlaB; diguanylate phosphodiesterase complement(544308..545858) Escherichia coli 536 4188119 YP_668447.1 CDS ECP_0519 NC_008253.1 546022 546492 R hypothetical protein complement(546022..546492) Escherichia coli 536 4188120 YP_668448.1 CDS ECP_0520 NC_008253.1 546608 547159 R maltose O-acetyltransferase complement(546608..547159) Escherichia coli 536 4188121 YP_668449.1 CDS ECP_0521 NC_008253.1 547333 547551 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(547333..547551) Escherichia coli 536 4188122 YP_668450.1 CDS ECP_0522 NC_008253.1 547577 547951 R hypothetical protein complement(547577..547951) Escherichia coli 536 4188123 YP_668451.1 CDS ECP_0523 NC_008253.1 548496 551645 R acriflavine resistance protein B complement(548496..551645) Escherichia coli 536 4188124 YP_668452.1 CDS ECP_0524 NC_008253.1 551668 552492 R acriflavin resistance protein A complement(551668..552492) Escherichia coli 536 4188125 YP_668453.1 CDS ECP_0525 NC_008253.1 553056 553649 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 553056..553649 Escherichia coli 536 4188126 YP_668454.1 CDS ECP_0526 NC_008253.1 553777 557139 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 553777..557139 Escherichia coli 536 4188127 YP_668455.1 CDS ECP_0527 NC_008253.1 557351 557512 R hypothetical protein complement(557351..557512) Escherichia coli 536 4188128 YP_668456.1 CDS ECP_0528 NC_008253.1 557526 558053 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(557526..558053) Escherichia coli 536 4188129 YP_668457.1 CDS ECP_0529 NC_008253.1 558123 558500 D hypothetical protein 558123..558500 Escherichia coli 536 4188130 YP_668458.1 CDS ECP_0530 NC_008253.1 558653 559204 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 558653..559204 Escherichia coli 536 4188131 YP_668459.1 CDS ECP_0531 NC_008253.1 559333 561264 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 559333..561264 Escherichia coli 536 4189238 YP_668460.1 CDS ECP_0532 NC_008253.1 561317 561646 D hypothetical protein 561317..561646 Escherichia coli 536 4189239 YP_668461.1 CDS recR NC_008253.1 561646 562251 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 561646..562251 Escherichia coli 536 4189240 YP_668462.1 CDS ECP_0534 NC_008253.1 562361 564235 D molecular chaperone; heat shock protein 90 562361..564235 Escherichia coli 536 4189241 YP_668463.1 CDS adk NC_008253.1 564416 565060 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 564416..565060 Escherichia coli 536 4189242 YP_668464.1 CDS hemH NC_008253.1 565192 566154 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 565192..566154 Escherichia coli 536 4189243 YP_668465.1 CDS ECP_0537 NC_008253.1 566129 567097 R acetyl esterase complement(566129..567097) Escherichia coli 536 4189244 YP_668466.1 CDS ECP_0538 NC_008253.1 567249 568553 D inosine-guanosine kinase 567249..568553 Escherichia coli 536 4189245 YP_668467.1 CDS ECP_0539 NC_008253.1 568683 570359 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(568683..570359) Escherichia coli 536 4189246 YP_668468.1 CDS ECP_0540 NC_008253.1 570597 571817 R fosmidomycin resistance protein complement(570597..571817) Escherichia coli 536 4189247 YP_668469.1 CDS ushA NC_008253.1 572035 573687 D UDP-sugar hydrolase; catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 572035..573687 Escherichia coli 536 4189248 YP_668470.1 CDS ECP_0542 NC_008253.1 573725 574228 R hypothetical protein complement(573725..574228) Escherichia coli 536 4189249 YP_668471.1 CDS ECP_0543 NC_008253.1 574225 575025 R hypothetical protein complement(574225..575025) Escherichia coli 536 4189250 YP_668472.1 CDS ECP_0544 NC_008253.1 575049 575528 R hypothetical protein complement(575049..575528) Escherichia coli 536 4189251 YP_668473.1 CDS ECP_0545 NC_008253.1 575732 576526 R ligase; hypothetical protein complement(575732..576526) Escherichia coli 536 4189252 YP_668474.1 CDS ECP_0546 NC_008253.1 576659 576961 D hypothetical protein 576659..576961 Escherichia coli 536 4189253 YP_668475.1 CDS ECP_0547 NC_008253.1 576997 577338 D HTH-type transcriptional regulator YbaQ 576997..577338 Escherichia coli 536 4189254 YP_668476.1 CDS ECP_0548 NC_008253.1 577396 577950 R copper-transporting P-type ATPase complement(577396..577950) Escherichia coli 536 4189255 YP_668477.1 CDS ECP_0549 NC_008253.1 577943 579901 R copper-transporting P-type ATPase complement(577943..579901) Escherichia coli 536 4189256 YP_668478.1 CDS ECP_0550 NC_008253.1 580163 581095 D catalyzes the formation of glutamate from glutamine; glutaminase 580163..581095 Escherichia coli 536 4189257 YP_668479.1 CDS ECP_0551 NC_008253.1 581098 582390 D amino acid transporter 581098..582390 Escherichia coli 536 4191687 YP_668480.1 CDS ECP_0552 NC_008253.1 582515 582922 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 582515..582922 Escherichia coli 536 4191688 YP_668481.1 CDS ECP_0553 NC_008253.1 582923 584146 R hypothetical protein complement(582923..584146) Escherichia coli 536 4191689 YP_668482.1 CDS ECP_0554 NC_008253.1 584265 584723 R hypothetical protein complement(584265..584723) Escherichia coli 536 4191690 YP_668483.1 CDS ECP_0555 NC_008253.1 584720 585637 R hypothetical protein complement(584720..585637) Escherichia coli 536 4191691 YP_668484.1 CDS ECP_0556 NC_008253.1 585783 586460 D ABC transporter ATP-binding protein 585783..586460 Escherichia coli 536 4191692 YP_668485.1 CDS ECP_0557 NC_008253.1 586447 587226 D hypothetical protein 586447..587226 Escherichia coli 536 4191693 YP_668486.1 CDS ECP_0558 NC_008253.1 587289 588179 R thioredoxin YbbN protein complement(587289..588179) Escherichia coli 536 4191694 YP_668487.1 CDS ECP_0559 NC_008253.1 588204 588974 R short chain dehydrogenase complement(588204..588974) Escherichia coli 536 4191695 YP_668488.1 CDS ECP_0560 NC_008253.1 589003 589659 R multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(589003..589659) Escherichia coli 536 4191696 YP_668489.1 CDS ECP_0561 NC_008253.1 589597 589824 D similar to N-terminal ATP-binding protein YbbA; ABC transporter 589597..589824 Escherichia coli 536 4191697 YP_668490.1 CDS ECP_0562 NC_008253.1 589826 590284 D similar to C-terminal ATP-binding protein YbbA; ABC transporter 589826..590284 Escherichia coli 536 4191698 YP_668491.1 CDS ECP_0563 NC_008253.1 590281 592695 D membrane protein YbbP 590281..592695 Escherichia coli 536 4191699 YP_668492.1 CDS ECP_0564 NC_008253.1 592836 593930 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(592836..593930) Escherichia coli 536 4191700 YP_668493.1 CDS ECP_0565 NC_008253.1 593999 594925 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(593999..594925) Escherichia coli 536 4191701 YP_668494.1 CDS ECP_0566 NC_008253.1 595155 595637 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 595155..595637 Escherichia coli 536 4191702 YP_668495.1 CDS ECP_0567 NC_008253.1 595715 596530 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 595715..596530 Escherichia coli 536 4191703 YP_668496.1 CDS ECP_0568 NC_008253.1 596620 598401 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 596620..598401 Escherichia coli 536 4191704 YP_668497.1 CDS ECP_0569 NC_008253.1 598414 599190 D hydroxypyruvate isomerase 598414..599190 Escherichia coli 536 4191705 YP_668498.1 CDS ECP_0570 NC_008253.1 599290 600168 D 2-hydroxy-3-oxopropionate reductase 599290..600168 Escherichia coli 536 4189508 YP_668499.1 CDS ECP_0571 NC_008253.1 600338 601792 D allantoin permease 600338..601792 Escherichia coli 536 4189509 YP_668500.1 CDS ECP_0572 NC_008253.1 601852 603213 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 601852..603213 Escherichia coli 536 4189510 YP_668501.1 CDS ECP_0573 NC_008253.1 603269 604570 D purine permease YbbY 603269..604570 Escherichia coli 536 4189511 YP_668502.1 CDS ECP_0574 NC_008253.1 604592 605737 D glycerate kinase 604592..605737 Escherichia coli 536 4189512 YP_668503.1 CDS ECP_0575 NC_008253.1 605866 606651 R hypothetical protein complement(605866..606651) Escherichia coli 536 4189513 YP_668504.1 CDS ECP_0576 NC_008253.1 606662 607897 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(606662..607897) Escherichia coli 536 4189514 YP_668505.1 CDS ECP_0577 NC_008253.1 607919 608968 R malate/L-lactate dehydrogenase complement(607919..608968) Escherichia coli 536 4189515 YP_668506.1 CDS ECP_0578 NC_008253.1 609285 610952 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 609285..610952 Escherichia coli 536 4189516 YP_668507.1 CDS ECP_0579 NC_008253.1 610962 612221 D hypothetical protein 610962..612221 Escherichia coli 536 4189517 YP_668508.1 CDS ECP_0580 NC_008253.1 612232 613047 D hypothetical protein 612232..613047 Escherichia coli 536 4189518 YP_668509.1 CDS ECP_0581 NC_008253.1 613044 613937 D carbamate kinase 613044..613937 Escherichia coli 536 4189519 YP_668510.1 CDS ECP_0582 NC_008253.1 614070 615137 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(614070..615137) Escherichia coli 536 4189520 YP_668511.1 CDS ECP_0583 NC_008253.1 615134 615643 R phosphoribosylaminoimidazole carboxylase catalytic subunit complement(615134..615643) Escherichia coli 536 4189521 YP_668512.1 CDS ECP_0584 NC_008253.1 615739 616068 R hypothetical protein complement(615739..616068) Escherichia coli 536 4189522 YP_668513.1 CDS ECP_0585 NC_008253.1 616180 616902 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(616180..616902) Escherichia coli 536 4189523 YP_668514.1 CDS ECP_0586 NC_008253.1 616905 617399 R peptidyl-prolyl cis-trans isomerase B complement(616905..617399) Escherichia coli 536 4189524 YP_668515.1 CDS cysS NC_008253.1 617573 618958 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 617573..618958 Escherichia coli 536 4189525 YP_668516.1 CDS ECP_0588 NC_008253.1 618994 619515 R membrane-bound metal-dependent hydrolase complement(618994..619515) Escherichia coli 536 4189526 YP_668517.1 CDS ECP_0589 NC_008253.1 619623 619835 R hypothetical protein complement(619623..619835) Escherichia coli 536 4189527 YP_668518.1 CDS ECP_0590 NC_008253.1 619837 620703 R bifunctional; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(619837..620703) Escherichia coli 536 4189889 YP_668519.1 CDS ECP_0591 NC_008253.1 620744 620941 D hypothetical protein 620744..620941 Escherichia coli 536 4189890 YP_668520.1 CDS ECP_0593 NC_008253.1 621058 621366 R similar to C-terminal prophage DLP12 integrase; DNA integration/recombination/invertion protein complement(621058..621366) Escherichia coli 536 4189892 YP_668521.1 CDS ECP_0594 NC_008253.1 621386 621685 R similar to N-terminal prophage DLP12 integrase; DNA integration/recombination/invertion protein complement(621386..621685) Escherichia coli 536 4189893 YP_668522.1 CDS ECP_0595 NC_008253.1 621739 621921 D hypothetical protein 621739..621921 Escherichia coli 536 4189894 YP_668523.1 CDS ECP_0596 NC_008253.1 622098 622754 R hypothetical protein complement(622098..622754) Escherichia coli 536 4189895 YP_668524.1 CDS ECP_0597 NC_008253.1 622998 623951 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(622998..623951) Escherichia coli 536 4189896 YP_668525.1 CDS ECP_0598 NC_008253.1 624610 625500 R hypothetical protein complement(624610..625500) Escherichia coli 536 4189897 YP_668526.1 CDS ECP_0599 NC_008253.1 625501 628473 R bacteriophage N4 receptor, outer membrane subunit complement(625501..628473) Escherichia coli 536 4189898 YP_668527.1 CDS nfrB NC_008253.1 628460 630697 R bacteriophage N4 adsorption protein B complement(628460..630697) Escherichia coli 536 4189899 YP_668528.1 CDS ECP_0601 NC_008253.1 630847 632289 R sensor kinase CusS complement(630847..632289) Escherichia coli 536 4189900 YP_668529.1 CDS ECP_0602 NC_008253.1 632279 632962 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(632279..632962) Escherichia coli 536 4189901 YP_668530.1 CDS ECP_0603 NC_008253.1 633119 634501 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 633119..634501 Escherichia coli 536 4189902 YP_668531.1 CDS ECP_0604 NC_008253.1 634525 634857 D copper-binding protein 634525..634857 Escherichia coli 536 4189903 YP_668532.1 CDS ECP_0605 NC_008253.1 634873 636096 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 634873..636096 Escherichia coli 536 4189904 YP_668533.1 CDS ECP_0606 NC_008253.1 636108 639251 D cation efflux system protein CusA 636108..639251 Escherichia coli 536 4189905 YP_668534.1 CDS ECP_0607 NC_008253.1 639353 640735 D phenylalanine transporter 639353..640735 Escherichia coli 536 4189906 YP_668535.1 CDS ECP_0608 NC_008253.1 640893 642140 R transporter complement(640893..642140) Escherichia coli 536 4191838 YP_668536.1 CDS ECP_0609 NC_008253.1 642248 642901 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(642248..642901) Escherichia coli 536 4191839 YP_668537.1 CDS ECP_0610 NC_008253.1 642980 643363 R hypothetical protein complement(642980..643363) Escherichia coli 536 4191840 YP_668538.1 CDS ECP_0611 NC_008253.1 643428 643676 R membrane protein YbdJ complement(643428..643676) Escherichia coli 536 4191841 YP_668539.1 CDS ECP_0612 NC_008253.1 643742 644860 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(643742..644860) Escherichia coli 536 4191842 YP_668540.1 CDS ECP_0613 NC_008253.1 645269 645457 D hypothetical protein 645269..645457 Escherichia coli 536 4191843 YP_668541.1 CDS ECP_0614 NC_008253.1 645579 646208 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(645579..646208) Escherichia coli 536 4191844 YP_668542.1 CDS ECP_0615 NC_008253.1 646374 648623 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(646374..648623) Escherichia coli 536 4191845 YP_668543.1 CDS ECP_0616 NC_008253.1 648865 650067 D enterobactin/ferric enterobactin esterase 648865..650067 Escherichia coli 536 4191846 YP_668544.1 CDS ECP_0617 NC_008253.1 650070 650288 D MbtH-like protein 650070..650288 Escherichia coli 536 4191847 YP_668545.1 CDS entF NC_008253.1 650285 654166 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 650285..654166 Escherichia coli 536 4191848 YP_668546.1 CDS ECP_0619 NC_008253.1 654382 655515 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 654382..655515 Escherichia coli 536 4191849 YP_668547.1 CDS ECP_0620 NC_008253.1 655512 656327 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(655512..656327) Escherichia coli 536 4191850 YP_668548.1 CDS ECP_0621 NC_008253.1 656324 657316 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(656324..657316) Escherichia coli 536 4191851 YP_668549.1 CDS ECP_0622 NC_008253.1 657313 658329 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(657313..658329) Escherichia coli 536 4191852 YP_668550.1 CDS ECP_0623 NC_008253.1 658428 659678 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 658428..659678 Escherichia coli 536 4191853 YP_668551.1 CDS ECP_0624 NC_008253.1 659682 660638 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(659682..660638) Escherichia coli 536 4191854 YP_668552.1 CDS ECP_0625 NC_008253.1 660827 662002 D isochorismate synthase 660827..662002 Escherichia coli 536 4191855 YP_668553.1 CDS entE NC_008253.1 662012 663622 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 662012..663622 Escherichia coli 536 4191856 YP_668554.1 CDS ECP_0627 NC_008253.1 663636 664493 D isochorismatase 663636..664493 Escherichia coli 536 4191857 YP_668555.1 CDS ECP_0628 NC_008253.1 664493 665239 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 664493..665239 Escherichia coli 536 4188185 YP_668556.1 CDS ECP_0629 NC_008253.1 665242 665655 D hypothetical protein 665242..665655 Escherichia coli 536 4188186 YP_668557.1 CDS ECP_0630 NC_008253.1 665836 667941 D carbon starvation protein A 665836..667941 Escherichia coli 536 4188187 YP_668558.1 CDS ECP_0631 NC_008253.1 668053 668250 D hypothetical protein 668053..668250 Escherichia coli 536 4188188 YP_668559.1 CDS ECP_0632 NC_008253.1 668260 669348 R member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein complement(668260..669348) Escherichia coli 536 4188189 YP_668560.1 CDS ECP_0633 NC_008253.1 669457 670617 D catalyzes the transfer of an amino moiety; aminotransferase 669457..670617 Escherichia coli 536 4188190 YP_668561.1 CDS ECP_0634 NC_008253.1 670618 671247 R hypothetical protein complement(670618..671247) Escherichia coli 536 4188191 YP_668562.1 CDS ECP_0635 NC_008253.1 671220 672440 R hypothetical protein complement(671220..672440) Escherichia coli 536 4188192 YP_668563.1 CDS ECP_0636 NC_008253.1 672587 673489 R transcriptional regulator YbdO complement(672587..673489) Escherichia coli 536 4188193 YP_668564.1 CDS dsbG NC_008253.1 673694 674440 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(673694..674440) Escherichia coli 536 4188194 YP_668565.1 CDS ECP_0638 NC_008253.1 674812 675375 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 674812..675375 Escherichia coli 536 4188195 YP_668566.1 CDS ECP_0639 NC_008253.1 675516 677111 D alkyl hydroperoxide reductase 675516..677111 Escherichia coli 536 4188196 YP_668567.1 CDS ECP_0640 NC_008253.1 677232 677660 R universal stress protein complement(677232..677660) Escherichia coli 536 4188197 YP_668568.1 CDS ECP_0641 NC_008253.1 678016 678426 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(678016..678426) Escherichia coli 536 4188198 YP_668569.1 CDS ECP_0642 NC_008253.1 678656 679480 R ribonuclease I complement(678656..679480) Escherichia coli 536 4188199 YP_668570.1 CDS ECP_0643 NC_008253.1 679576 681039 R citrate/succinate antiporter complement(679576..681039) Escherichia coli 536 4188200 YP_668571.1 CDS citG NC_008253.1 681090 681968 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(681090..681968) Escherichia coli 536 4188201 YP_668572.1 CDS citX NC_008253.1 681943 682494 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(681943..682494) Escherichia coli 536 4188202 YP_668573.1 CDS ECP_0646 NC_008253.1 682498 684030 R citrate lyase subunit alpha complement(682498..684030) Escherichia coli 536 4188203 YP_668574.1 CDS ECP_0647 NC_008253.1 684041 684949 R citrate lyase subunit beta complement(684041..684949) Escherichia coli 536 4188471 YP_668575.1 CDS ECP_0648 NC_008253.1 684946 685242 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(684946..685242) Escherichia coli 536 4188472 YP_668576.1 CDS ECP_0649 NC_008253.1 685257 686315 R citrate lyase synthetase complement(685257..686315) Escherichia coli 536 4188473 YP_668577.1 CDS ECP_0650 NC_008253.1 686695 688353 D sensor kinase DpiB 686695..688353 Escherichia coli 536 4188474 YP_668578.1 CDS dpiA NC_008253.1 688322 689002 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 688322..689002 Escherichia coli 536 4188475 YP_668579.1 CDS dcuC NC_008253.1 689043 690428 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(689043..690428) Escherichia coli 536 4188476 YP_668580.1 CDS pagP NC_008253.1 691015 691575 D antimicrobial peptide resistance and lipid A acylation protein; catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 691015..691575 Escherichia coli 536 4188477 YP_668581.1 CDS cspE NC_008253.1 691750 691959 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 691750..691959 Escherichia coli 536 4188478 YP_668582.1 CDS ECP_0655 NC_008253.1 692013 692396 R protein CrcB complement(692013..692396) Escherichia coli 536 4188479 YP_668583.1 CDS ECP_0656 NC_008253.1 692492 693280 D hypothetical protein 692492..693280 Escherichia coli 536 4188480 YP_668584.1 CDS tatE NC_008253.1 693409 693612 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 693409..693612 Escherichia coli 536 4188481 YP_668585.1 CDS ECP_0658 NC_008253.1 693712 694677 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(693712..694677) Escherichia coli 536 4188482 YP_668586.1 CDS ECP_0659 NC_008253.1 694909 695097 R hypothetical protein complement(694909..695097) Escherichia coli 536 4188483 YP_668587.1 CDS lipB NC_008253.1 695497 696138 R lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase complement(695497..696138) Escherichia coli 536 4188484 YP_668588.1 CDS ECP_0661 NC_008253.1 696239 696502 R hypothetical protein complement(696239..696502) Escherichia coli 536 4188485 YP_668589.1 CDS ECP_0662 NC_008253.1 696612 697823 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(696612..697823) Escherichia coli 536 4188486 YP_668590.1 CDS ECP_0663 NC_008253.1 697963 699051 R rare lipoprotein A complement(697963..699051) Escherichia coli 536 4188487 YP_668591.1 CDS ECP_0664 NC_008253.1 699062 700174 R cell wall shape-determining protein complement(699062..700174) Escherichia coli 536 4188488 YP_668592.1 CDS ECP_0665 NC_008253.1 700177 702078 R penicillin-binding protein 2 complement(700177..702078) Escherichia coli 536 4188489 YP_668593.1 CDS ECP_0666 NC_008253.1 702109 702576 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(702109..702576) Escherichia coli 536 4188490 YP_668594.1 CDS ECP_0667 NC_008253.1 702580 702897 R hypothetical protein complement(702580..702897) Escherichia coli 536 4190913 YP_668595.1 CDS ECP_0668 NC_008253.1 703157 703768 R phosphoglycerate mutase complement(703157..703768) Escherichia coli 536 4190914 YP_668596.1 CDS nadD NC_008253.1 703792 704433 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(703792..704433) Escherichia coli 536 4190915 YP_668597.1 CDS holA NC_008253.1 704435 705466 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(704435..705466) Escherichia coli 536 4190916 YP_668598.1 CDS ECP_0671 NC_008253.1 705466 706047 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(705466..706047) Escherichia coli 536 4190917 YP_668599.1 CDS leuS NC_008253.1 706062 708644 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(706062..708644) Escherichia coli 536 4190918 YP_668600.1 CDS ECP_0673 NC_008253.1 708879 709361 D hypothetical protein 708879..709361 Escherichia coli 536 4190919 YP_668601.1 CDS rihA NC_008253.1 709406 710341 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(709406..710341) Escherichia coli 536 4190920 YP_668602.1 CDS ECP_0675 NC_008253.1 710459 711184 R glutamate/aspartate transport ATP-binding protein GltL complement(710459..711184) Escherichia coli 536 4190921 YP_668603.1 CDS ECP_0676 NC_008253.1 711184 711858 R glutamate/aspartate transport system permease GltK complement(711184..711858) Escherichia coli 536 4190922 YP_668604.1 CDS ECP_0677 NC_008253.1 711858 712598 R glutamate/aspartate transport system permease GltJ complement(711858..712598) Escherichia coli 536 4190923 YP_668605.1 CDS ECP_0678 NC_008253.1 712768 713676 R glutamate and aspartate transporter subunit complement(712768..713676) Escherichia coli 536 4190924 YP_668606.1 CDS ECP_0679 NC_008253.1 714130 716007 D outer membrane protein 714130..716007 Escherichia coli 536 4190925 YP_668607.1 CDS lnt NC_008253.1 716134 717672 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(716134..717672) Escherichia coli 536 4190926 YP_668608.1 CDS ECP_0681 NC_008253.1 717697 718575 R magnesium and cobalt efflux protein CorC complement(717697..718575) Escherichia coli 536 4190927 YP_668609.1 CDS ECP_0682 NC_008253.1 718665 719132 R metalloprotease complement(718665..719132) Escherichia coli 536 4190928 YP_668610.1 CDS ECP_0683 NC_008253.1 719129 720208 R ATP-binding PhoH-like protein complement(719129..720208) Escherichia coli 536 4190929 YP_668611.1 CDS ECP_0684 NC_008253.1 720322 721746 R tRNA-thiotransferase; MiaB protein complement(720322..721746) Escherichia coli 536 4190930 YP_668612.1 CDS ubiF NC_008253.1 721892 723067 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 721892..723067 Escherichia coli 536 4190931 YP_668613.1 CDS asnB NC_008253.1 723914 725578 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(723914..725578) Escherichia coli 536 4190061 YP_668614.1 CDS ECP_0687 NC_008253.1 725835 726587 R UMP phosphatase complement(725835..726587) Escherichia coli 536 4190062 YP_668615.1 CDS ECP_0688 NC_008253.1 726635 727855 R N-acetylglucosamine repressor NagC complement(726635..727855) Escherichia coli 536 4190063 YP_668616.1 CDS nagA NC_008253.1 727864 729012 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(727864..729012) Escherichia coli 536 4190064 YP_668617.1 CDS nagB NC_008253.1 729072 729872 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(729072..729872) Escherichia coli 536 4190065 YP_668618.1 CDS ECP_0691 NC_008253.1 730205 732151 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; N-acetyl glucosamine specific PTS system components IIABC 730205..732151 Escherichia coli 536 4190066 YP_668619.1 CDS ECP_0692 NC_008253.1 732240 733754 R membrane transporter complement(732240..733754) Escherichia coli 536 4190067 YP_668620.1 CDS ECP_0693 NC_008253.1 734001 735170 R hypothetical protein complement(734001..735170) Escherichia coli 536 4190068 YP_668621.1 CDS ECP_0694 NC_008253.1 735206 735964 R integral membrane transport protein complement(735206..735964) Escherichia coli 536 4190069 YP_668622.1 CDS ECP_0695 NC_008253.1 736024 736911 R dihydrodipicolinate synthase complement(736024..736911) Escherichia coli 536 4190070 YP_668623.1 CDS ECP_0696 NC_008253.1 736915 738072 R iron-containing alcohol dehydrogenase complement(736915..738072) Escherichia coli 536 4190071 YP_668624.1 CDS ECP_0697 NC_008253.1 738242 739477 D inner membrane protein 738242..739477 Escherichia coli 536 4190072 YP_668625.1 CDS pdxA NC_008253.1 739470 740456 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 739470..740456 Escherichia coli 536 4190073 YP_668626.1 CDS ECP_0699 NC_008253.1 740458 741219 D DeoR family transcriptional regulator 740458..741219 Escherichia coli 536 4190074 YP_668627.1 CDS ECP_0700 NC_008253.1 741439 743103 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 741439..743103 Escherichia coli 536 4190075 YP_668628.1 CDS ECP_0701 NC_008253.1 743544 744950 D outer membrane protein YbfM 743544..744950 Escherichia coli 536 4190076 YP_668629.1 CDS ECP_0702 NC_008253.1 745000 745326 D lipoprotein YbfN 745000..745326 Escherichia coli 536 4190077 YP_668630.1 CDS fur NC_008253.1 745410 745856 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(745410..745856) Escherichia coli 536 4190078 YP_668631.1 CDS ECP_0704 NC_008253.1 745901 746155 D hypothetical protein 745901..746155 Escherichia coli 536 4190079 YP_668632.1 CDS ECP_0705 NC_008253.1 746145 746675 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(746145..746675) Escherichia coli 536 4190080 YP_668633.1 CDS ECP_0706 NC_008253.1 746815 747177 R LexA regulated protein complement(746815..747177) Escherichia coli 536 4187737 YP_668634.1 CDS ECP_0707 NC_008253.1 747248 748012 R hypothetical protein complement(747248..748012) Escherichia coli 536 4187738 YP_668635.1 CDS ECP_0708 NC_008253.1 748197 748742 D negative modulator of initiation of replication; negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 748197..748742 Escherichia coli 536 4187739 YP_668636.1 CDS ECP_0709 NC_008253.1 748768 750408 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 748768..750408 Escherichia coli 536 4187740 YP_668637.1 CDS potE NC_008253.1 750465 751784 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(750465..751784) Escherichia coli 536 4187741 YP_668638.1 CDS ECP_0711 NC_008253.1 751781 753988 R ornithine decarboxylase complement(751781..753988) Escherichia coli 536 4187742 YP_668639.1 CDS ECP_0712 NC_008253.1 754668 755345 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(754668..755345) Escherichia coli 536 4187743 YP_668640.1 CDS ECP_0715 NC_008253.1 758020 758592 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(758020..758592) Escherichia coli 536 4187746 YP_668641.1 CDS ECP_0716 NC_008253.1 758601 760649 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(758601..760649) Escherichia coli 536 4187747 YP_668642.1 CDS ECP_0717 NC_008253.1 760672 762345 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(760672..762345) Escherichia coli 536 4187748 YP_668643.1 CDS ECP_0718 NC_008253.1 762345 762434 R hypothetical protein complement(762345..762434) Escherichia coli 536 4187749 YP_668644.1 CDS ECP_0719 NC_008253.1 762747 762953 D hypothetical protein 762747..762953 Escherichia coli 536 4187750 YP_668645.1 CDS ECP_0720 NC_008253.1 763054 763563 D hypothetical protein 763054..763563 Escherichia coli 536 4187751 YP_668646.1 CDS ECP_0721 NC_008253.1 763560 764978 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 763560..764978 Escherichia coli 536 4187752 YP_668647.1 CDS ECP_0722 NC_008253.1 765020 766501 R POT family transport protein YbgH complement(765020..766501) Escherichia coli 536 4187753 YP_668648.1 CDS ECP_0723 NC_008253.1 766772 767515 D hydrolase-oxidase 766772..767515 Escherichia coli 536 4191405 YP_668649.1 CDS ECP_0724 NC_008253.1 767538 768323 D hypothetical protein 767538..768323 Escherichia coli 536 4191406 YP_668650.1 CDS ECP_0725 NC_008253.1 768202 769134 D carboxylase; hypothetical protein 768202..769134 Escherichia coli 536 4191407 YP_668651.1 CDS ECP_0726 NC_008253.1 769124 769858 D LamB/YcsF family protein 769124..769858 Escherichia coli 536 4191408 YP_668652.1 CDS ECP_0727 NC_008253.1 769894 770685 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 769894..770685 Escherichia coli 536 4191409 YP_668653.1 CDS ECP_0728 NC_008253.1 770682 771728 R hypothetical protein complement(770682..771728) Escherichia coli 536 4191410 YP_668654.1 CDS ECP_0729 NC_008253.1 771880 771990 R hypothetical protein complement(771880..771990) Escherichia coli 536 4191411 YP_668655.1 CDS ECP_0730 NC_008253.1 772012 772245 R hypothetical protein complement(772012..772245) Escherichia coli 536 4191412 YP_668656.1 CDS gltA NC_008253.1 772402 773685 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(772402..773685) Escherichia coli 536 4191413 YP_668657.1 CDS ECP_0732 NC_008253.1 773667 773858 D hypothetical protein 773667..773858 Escherichia coli 536 4191414 YP_668658.1 CDS sdhC NC_008253.1 774379 774783 D succinate dehydrogenase cytochrome b556 large membrane subunit 774379..774783 Escherichia coli 536 4191415 YP_668659.1 CDS sdhD NC_008253.1 774777 775124 D succinate dehydrogenase cytochrome b556 small membrane subunit 774777..775124 Escherichia coli 536 4191416 YP_668660.1 CDS sdhA NC_008253.1 775124 776890 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 775124..776890 Escherichia coli 536 4191417 YP_668661.1 CDS sdhB NC_008253.1 776906 777622 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 776906..777622 Escherichia coli 536 4191418 YP_668662.1 CDS sucA NC_008253.1 777984 780785 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 777984..780785 Escherichia coli 536 4191419 YP_668663.1 CDS ECP_0738 NC_008253.1 780800 782017 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 780800..782017 Escherichia coli 536 4191420 YP_668664.1 CDS sucC NC_008253.1 782111 783277 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 782111..783277 Escherichia coli 536 4191421 YP_668665.1 CDS ECP_0740 NC_008253.1 783277 784146 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 783277..784146 Escherichia coli 536 4191422 YP_668666.1 CDS ECP_0741 NC_008253.1 784386 785501 D hypothetical protein 784386..785501 Escherichia coli 536 4191423 YP_668667.1 CDS ECP_0742 NC_008253.1 785455 785727 D hypothetical protein 785455..785727 Escherichia coli 536 4190657 YP_668668.1 CDS ECP_0743 NC_008253.1 786831 788399 D cytochrome D ubiquinol oxidase subunit I 786831..788399 Escherichia coli 536 4190658 YP_668669.1 CDS ECP_0744 NC_008253.1 788415 789554 D cytochrome D ubiquinol oxidase subunit II 788415..789554 Escherichia coli 536 4190659 YP_668670.1 CDS ECP_0745 NC_008253.1 789569 789682 D hypothetical protein 789569..789682 Escherichia coli 536 4190660 YP_668671.1 CDS ECP_0746 NC_008253.1 789682 789975 D hypothetical protein 789682..789975 Escherichia coli 536 4190661 YP_668672.1 CDS ECP_0747 NC_008253.1 790125 790529 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 790125..790529 Escherichia coli 536 4190662 YP_668673.1 CDS ECP_0748 NC_008253.1 790535 791218 D membrane-spanning inner membrane protein; membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 790535..791218 Escherichia coli 536 4190663 YP_668674.1 CDS ECP_0749 NC_008253.1 791222 791650 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 791222..791650 Escherichia coli 536 4190664 YP_668675.1 CDS tolA NC_008253.1 791715 792980 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 791715..792980 Escherichia coli 536 4190665 YP_668676.1 CDS tolB NC_008253.1 793113 794405 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 793113..794405 Escherichia coli 536 4190666 YP_668677.1 CDS ECP_0752 NC_008253.1 794440 794961 D peptidoglycan-associated outer membrane lipoprotein 794440..794961 Escherichia coli 536 4190667 YP_668678.1 CDS ECP_0753 NC_008253.1 794971 795762 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 794971..795762 Escherichia coli 536 4190668 YP_668679.1 CDS ECP_0761 NC_008253.1 796908 797951 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 796908..797951 Escherichia coli 536 4188081 YP_668680.1 CDS ECP_0762 NC_008253.1 797989 798708 D intergral membrane NMN transport protein PnuC 797989..798708 Escherichia coli 536 4188082 YP_668681.1 CDS ECP_0763 NC_008253.1 798705 799646 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(798705..799646) Escherichia coli 536 4188083 YP_668682.1 CDS ECP_0764 NC_008253.1 799761 800141 R hypothetical protein complement(799761..800141) Escherichia coli 536 4188084 YP_668683.1 CDS ECP_0765 NC_008253.1 800457 801509 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 800457..801509 Escherichia coli 536 4188085 YP_668684.1 CDS ECP_0766 NC_008253.1 801676 802428 R phosphoglycerate mutase complement(801676..802428) Escherichia coli 536 4188086 YP_668685.1 CDS galM NC_008253.1 802631 803671 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(802631..803671) Escherichia coli 536 4188087 YP_668686.1 CDS ECP_0768 NC_008253.1 803665 804813 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(803665..804813) Escherichia coli 536 4188088 YP_668687.1 CDS ECP_0769 NC_008253.1 804817 805863 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(804817..805863) Escherichia coli 536 4188089 YP_668688.1 CDS ECP_0770 NC_008253.1 805873 806889 R UDP-galactose-4-epimerase complement(805873..806889) Escherichia coli 536 4188090 YP_668689.1 CDS ECP_0771 NC_008253.1 807151 808623 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(807151..808623) Escherichia coli 536 4188091 YP_668690.1 CDS ECP_0772 NC_008253.1 808691 809479 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(808691..809479) Escherichia coli 536 4188092 YP_668691.1 CDS ECP_0773 NC_008253.1 809608 809757 D outer membrane or exported protein 809608..809757 Escherichia coli 536 4191073 YP_668692.1 CDS ECP_0774 NC_008253.1 809693 809902 D hypothetical protein 809693..809902 Escherichia coli 536 4191074 YP_668693.1 CDS modA NC_008253.1 809924 810697 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 809924..810697 Escherichia coli 536 4191075 YP_668694.1 CDS modB NC_008253.1 810697 811386 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 810697..811386 Escherichia coli 536 4191076 YP_668695.1 CDS modC NC_008253.1 811389 812447 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 811389..812447 Escherichia coli 536 4191077 YP_668696.1 CDS ECP_0778 NC_008253.1 812448 813266 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(812448..813266) Escherichia coli 536 4191078 YP_668697.1 CDS ECP_0779 NC_008253.1 813421 814416 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 813421..814416 Escherichia coli 536 4191079 YP_668698.1 CDS ECP_0780 NC_008253.1 814457 815215 R similar to C-terminal transcriptional regulator YbhD; transcriptional regulator complement(814457..815215) Escherichia coli 536 4191080 YP_668699.1 CDS ECP_0781 NC_008253.1 815233 815472 R similar to N-terminal transcriptional regulator YbhD; transcriptional regulator complement(815233..815472) Escherichia coli 536 4191081 YP_668700.1 CDS ECP_0782 NC_008253.1 815593 816645 D hypothetical protein 815593..816645 Escherichia coli 536 4191082 YP_668701.1 CDS ECP_0783 NC_008253.1 816721 818154 D membrane transport protein 816721..818154 Escherichia coli 536 4191083 YP_668702.1 CDS ECP_0784 NC_008253.1 818337 820598 D hypothetical protein 818337..820598 Escherichia coli 536 4191084 YP_668703.1 CDS ECP_0785 NC_008253.1 820739 822022 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase complement(820739..822022) Escherichia coli 536 4191085 YP_668704.1 CDS ECP_0786 NC_008253.1 822174 822650 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(822174..822650) Escherichia coli 536 4191086 YP_668705.1 CDS ECP_0787 NC_008253.1 822759 823889 D virulence protein GipA 822759..823889 Escherichia coli 536 4191087 YP_668706.1 CDS ECP_0788 NC_008253.1 824000 825400 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(824000..825400) Escherichia coli 536 4191088 YP_668707.1 CDS ECP_0789 NC_008253.1 825376 826416 D biotin synthase 825376..826416 Escherichia coli 536 4191089 YP_668708.1 CDS ECP_0790 NC_008253.1 826413 827567 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 826413..827567 Escherichia coli 536 4191090 YP_668709.1 CDS ECP_0791 NC_008253.1 827554 828309 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 827554..828309 Escherichia coli 536 4191091 YP_668710.1 CDS bioD NC_008253.1 828302 828979 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 828302..828979 Escherichia coli 536 4191092 YP_668711.1 CDS ECP_0793 NC_008253.1 829558 831579 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 829558..831579 Escherichia coli 536 4189907 YP_668712.1 CDS ECP_0794 NC_008253.1 831617 832525 R hypothetical protein complement(831617..832525) Escherichia coli 536 4189908 YP_668713.1 CDS moaA NC_008253.1 832889 833911 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 832889..833911 Escherichia coli 536 4189909 YP_668714.1 CDS ECP_0796 NC_008253.1 833933 834445 D molybdenum cofactor biosynthesis protein B 833933..834445 Escherichia coli 536 4189910 YP_668715.1 CDS moaC NC_008253.1 834448 834933 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein C 834448..834933 Escherichia coli 536 4189911 YP_668716.1 CDS moaD NC_008253.1 834926 835171 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 834926..835171 Escherichia coli 536 4189912 YP_668717.1 CDS moaE NC_008253.1 835173 835625 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase large subunit 835173..835625 Escherichia coli 536 4189913 YP_668718.1 CDS ECP_0800 NC_008253.1 835762 836466 D hypothetical protein 835762..836466 Escherichia coli 536 4189914 YP_668719.1 CDS ECP_0801 NC_008253.1 836672 837385 D hypothetical protein 836672..837385 Escherichia coli 536 4189915 YP_668720.1 CDS ECP_0802 NC_008253.1 837421 838377 R hypothetical protein complement(837421..838377) Escherichia coli 536 4189916 YP_668721.1 CDS ECP_0803 NC_008253.1 838377 839618 R phospholipase; cardiolipin synthase 2 complement(838377..839618) Escherichia coli 536 4189917 YP_668722.1 CDS ECP_0804 NC_008253.1 839615 840376 R hypothetical protein complement(839615..840376) Escherichia coli 536 4189918 YP_668723.1 CDS ECP_0805 NC_008253.1 840509 840919 D hypothetical protein 840509..840919 Escherichia coli 536 4189919 YP_668724.1 CDS ECP_0806 NC_008253.1 840881 841987 R membrane protein YbhR complement(840881..841987) Escherichia coli 536 4189920 YP_668725.1 CDS ECP_0807 NC_008253.1 841998 843131 R inner membrane protein complement(841998..843131) Escherichia coli 536 4189921 YP_668726.1 CDS ECP_0808 NC_008253.1 843124 844860 R ABC transporter ATP-binding protein complement(843124..844860) Escherichia coli 536 4189922 YP_668727.1 CDS ECP_0809 NC_008253.1 844853 845848 R hypothetical protein complement(844853..845848) Escherichia coli 536 4189923 YP_668728.1 CDS ECP_0810 NC_008253.1 845851 846534 R DNA-binding transcriptional regulator complement(845851..846534) Escherichia coli 536 4189924 YP_668729.1 CDS ECP_0811 NC_008253.1 846751 848112 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 846751..848112 Escherichia coli 536 4189925 YP_668730.1 CDS ECP_0812 NC_008253.1 848345 848650 R hypothetical protein complement(848345..848650) Escherichia coli 536 4190101 YP_668731.1 CDS dinG NC_008253.1 848649 850799 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 848649..850799 Escherichia coli 536 4190102 YP_668732.1 CDS ECP_0814 NC_008253.1 850827 851789 D glycosyl transferase family protein 850827..851789 Escherichia coli 536 4190103 YP_668733.1 CDS ECP_0815 NC_008253.1 851930 853015 D hypothetical protein 851930..853015 Escherichia coli 536 4190104 YP_668734.1 CDS ECP_0816 NC_008253.1 853243 853503 R hypothetical protein complement(853243..853503) Escherichia coli 536 4190105 YP_668735.1 CDS ECP_0817 NC_008253.1 853768 854034 R hypothetical protein complement(853768..854034) Escherichia coli 536 4190106 YP_668736.1 CDS ECP_0818 NC_008253.1 854108 854785 R hydroxylase complement(854108..854785) Escherichia coli 536 4190107 YP_668737.1 CDS ECP_0819 NC_008253.1 855001 857283 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(855001..857283) Escherichia coli 536 4190108 YP_668738.1 CDS ECP_0820 NC_008253.1 857548 857808 R hypothetical protein complement(857548..857808) Escherichia coli 536 4190109 YP_668739.1 CDS ECP_0821 NC_008253.1 858084 859010 D SAM-dependent methyltransferase 858084..859010 Escherichia coli 536 4190110 YP_668740.1 CDS ECP_0822 NC_008253.1 859007 861232 R hypothetical protein complement(859007..861232) Escherichia coli 536 4190111 YP_668741.1 CDS glnQ NC_008253.1 861349 862071 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(861349..862071) Escherichia coli 536 4190112 YP_668742.1 CDS glnP NC_008253.1 862068 862727 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(862068..862727) Escherichia coli 536 4190113 YP_668743.1 CDS glnH NC_008253.1 862866 863612 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(862866..863612) Escherichia coli 536 4190114 YP_668744.1 CDS ECP_0826 NC_008253.1 864016 864519 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(864016..864519) Escherichia coli 536 4190115 YP_668745.1 CDS ECP_0827 NC_008253.1 864819 865706 R threonine and homoserine efflux system complement(864819..865706) Escherichia coli 536 4190116 YP_668746.1 CDS ompX NC_008253.1 866059 866574 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 866059..866574 Escherichia coli 536 4190117 YP_668747.1 CDS ECP_0829 NC_008253.1 866624 868207 R membrane protein YbiP complement(866624..868207) Escherichia coli 536 4190118 YP_668748.1 CDS ECP_0830 NC_008253.1 868231 868446 D hypothetical protein 868231..868446 Escherichia coli 536 4190119 YP_668749.1 CDS ECP_0831 NC_008253.1 868793 869260 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 868793..869260 Escherichia coli 536 4190120 YP_668750.1 CDS ECP_0832 NC_008253.1 869257 870375 D hypothetical protein 869257..870375 Escherichia coli 536 4189679 YP_668751.1 CDS ECP_0833 NC_008253.1 870433 871353 R hypothetical protein complement(870433..871353) Escherichia coli 536 4189680 YP_668752.1 CDS ECP_0834 NC_008253.1 871572 873164 D ABC transporter ATP-binding protein 871572..873164 Escherichia coli 536 4189681 YP_668753.1 CDS ECP_0835 NC_008253.1 873364 874179 R HAD family hydrolase complement(873364..874179) Escherichia coli 536 4189682 YP_668754.1 CDS ECP_0836 NC_008253.1 874325 876757 R formate acetyltransferase 3 complement(874325..876757) Escherichia coli 536 4189683 YP_668755.1 CDS ECP_0837 NC_008253.1 876763 877662 R pyruvate formate-lyase 3 activating enzyme complement(876763..877662) Escherichia coli 536 4189684 YP_668756.1 CDS ECP_0838 NC_008253.1 877793 878455 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 877793..878455 Escherichia coli 536 4189685 YP_668757.1 CDS ECP_0839 NC_008253.1 878531 879280 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(878531..879280) Escherichia coli 536 4189686 YP_668758.1 CDS ECP_0840 NC_008253.1 879280 880515 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(879280..880515) Escherichia coli 536 4189687 YP_668759.1 CDS ECP_0841 NC_008253.1 880719 881684 D L-asparaginase 880719..881684 Escherichia coli 536 4189688 YP_668760.1 CDS ECP_0842 NC_008253.1 881704 883542 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 881704..883542 Escherichia coli 536 4189689 YP_668761.1 CDS ECP_0843 NC_008253.1 883562 883852 D similar to N-terminal part of binding protein YliB; hypothetical protein 883562..883852 Escherichia coli 536 4189690 YP_668762.1 CDS ECP_0844 NC_008253.1 883887 885101 D similar to C-terminal part of binding protein YliB; hypothetical protein 883887..885101 Escherichia coli 536 4189691 YP_668763.1 CDS ECP_0845 NC_008253.1 885119 886039 D ABC transporter substrate-binding protein 885119..886039 Escherichia coli 536 4189692 YP_668764.1 CDS ECP_0846 NC_008253.1 886042 886953 D ABC transporter inner membrane component 886042..886953 Escherichia coli 536 4189693 YP_668765.1 CDS ECP_0847 NC_008253.1 887130 889478 D hypothetical protein 887130..889478 Escherichia coli 536 4189694 YP_668766.1 CDS ECP_0848 NC_008253.1 889573 890814 D hypothetical protein 889573..890814 Escherichia coli 536 4189695 YP_668767.1 CDS ECP_0849 NC_008253.1 890861 892186 R hypothetical protein complement(890861..892186) Escherichia coli 536 4189696 YP_668768.1 CDS bssR NC_008253.1 892399 892782 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 892399..892782 Escherichia coli 536 4189697 YP_668769.1 CDS ECP_0851 NC_008253.1 892893 894008 D hypothetical protein 892893..894008 Escherichia coli 536 4188903 YP_668770.1 CDS ECP_0852 NC_008253.1 894005 894631 R GST-like protein complement(894005..894631) Escherichia coli 536 4188904 YP_668771.1 CDS ECP_0853 NC_008253.1 894877 896079 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 894877..896079 Escherichia coli 536 4188905 YP_668772.1 CDS ECP_0854 NC_008253.1 896126 896884 R DNA-binding transcriptional repressor DeoR complement(896126..896884) Escherichia coli 536 4188906 YP_668773.1 CDS ECP_0855 NC_008253.1 896942 897538 R undecaprenyl pyrophosphate phosphatase complement(896942..897538) Escherichia coli 536 4188907 YP_668774.1 CDS ECP_0856 NC_008253.1 897824 899056 D multidrug translocase MmdfA 897824..899056 Escherichia coli 536 4188908 YP_668775.1 CDS ECP_0857 NC_008253.1 899097 899375 R hypothetical protein complement(899097..899375) Escherichia coli 536 4188909 YP_668776.1 CDS ECP_0858 NC_008253.1 899467 900282 R HAD family hydrolase complement(899467..900282) Escherichia coli 536 4188910 YP_668777.1 CDS ECP_0859 NC_008253.1 900282 901490 R membrane protein YbjJ complement(900282..901490) Escherichia coli 536 4188911 YP_668778.1 CDS ECP_0860 NC_008253.1 901574 902110 D transcriptional regulator YbjK 901574..902110 Escherichia coli 536 4188912 YP_668779.1 CDS ECP_0861 NC_008253.1 902285 903970 R hypothetical protein complement(902285..903970) Escherichia coli 536 4188913 YP_668780.1 CDS ECP_0862 NC_008253.1 904240 904617 D inner membrane protein YbjM 904240..904617 Escherichia coli 536 4188914 YP_668781.1 CDS grxA NC_008253.1 904647 904904 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(904647..904904) Escherichia coli 536 4188915 YP_668782.1 CDS ECP_0864 NC_008253.1 905064 905351 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 905064..905351 Escherichia coli 536 4188916 YP_668783.1 CDS ECP_0865 NC_008253.1 905335 906057 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 905335..906057 Escherichia coli 536 4188917 YP_668784.1 CDS ECP_0866 NC_008253.1 906118 907020 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 906118..907020 Escherichia coli 536 4188918 YP_668785.1 CDS ECP_0867 NC_008253.1 907108 907584 D cytoplasmic protein YbjN 907108..907584 Escherichia coli 536 4188919 YP_668786.1 CDS ECP_0868 NC_008253.1 907934 909046 D putrescine ABC transporter periplasmic-binding protein 907934..909046 Escherichia coli 536 4188920 YP_668787.1 CDS potG NC_008253.1 909060 910274 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 909060..910274 Escherichia coli 536 4188921 YP_668788.1 CDS ECP_0870 NC_008253.1 910284 911228 D putrescine ABC transporter membrane protein 910284..911228 Escherichia coli 536 4188922 YP_668789.1 CDS ECP_0871 NC_008253.1 911225 912070 D putrescine ABC transporter membrane protein 911225..912070 Escherichia coli 536 4187547 YP_668790.1 CDS ECP_0872 NC_008253.1 912130 912618 D hypothetical protein 912130..912618 Escherichia coli 536 4187548 YP_668791.1 CDS rumB NC_008253.1 912659 913786 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 912659..913786 Escherichia coli 536 4187549 YP_668792.1 CDS artM NC_008253.1 914773 915441 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(914773..915441) Escherichia coli 536 4187552 YP_668793.1 CDS ECP_0877 NC_008253.1 915441 916157 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(915441..916157) Escherichia coli 536 4187553 YP_668794.1 CDS ECP_0878 NC_008253.1 916164 916895 R arginine/ornithine ABC transporter substrate-binding protein complement(916164..916895) Escherichia coli 536 4187554 YP_668795.1 CDS artP NC_008253.1 916913 917641 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(916913..917641) Escherichia coli 536 4187555 YP_668796.1 CDS ECP_0880 NC_008253.1 917859 918374 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(917859..918374) Escherichia coli 536 4187556 YP_668797.1 CDS ECP_0881 NC_008253.1 918500 918823 D hypothetical protein 918500..918823 Escherichia coli 536 4187557 YP_668798.1 CDS ECP_0882 NC_008253.1 918820 919650 D N-acetylmuramoyl-L-alanine amidase 918820..919650 Escherichia coli 536 4187558 YP_668799.1 CDS ECP_0883 NC_008253.1 919647 920696 R nucleotide di-P-sugar epimerase or dehydratase complement(919647..920696) Escherichia coli 536 4187559 YP_668800.1 CDS ECP_0884 NC_008253.1 920759 922189 R hypothetical protein complement(920759..922189) Escherichia coli 536 4187560 YP_668801.1 CDS ECP_0885 NC_008253.1 922200 923201 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(922200..923201) Escherichia coli 536 4187561 YP_668802.1 CDS ECP_0886 NC_008253.1 923238 924956 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(923238..924956) Escherichia coli 536 4187562 YP_668803.1 CDS ECP_0887 NC_008253.1 925089 926057 R HCP oxidoreductase complement(925089..926057) Escherichia coli 536 4187563 YP_668804.1 CDS ECP_0888 NC_008253.1 926069 927721 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(926069..927721) Escherichia coli 536 4191819 YP_668805.1 CDS ECP_0889 NC_008253.1 927865 928764 R hypothetical protein complement(927865..928764) Escherichia coli 536 4191820 YP_668806.1 CDS ECP_0890 NC_008253.1 929085 929780 R major intrinsic protein; porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(929085..929780) Escherichia coli 536 4191821 YP_668807.1 CDS ECP_0891 NC_008253.1 930206 931864 D hypothetical protein 930206..931864 Escherichia coli 536 4191822 YP_668808.1 CDS ECP_0892 NC_008253.1 931861 932853 R hypothetical protein complement(931861..932853) Escherichia coli 536 4191823 YP_668809.1 CDS ECP_0893 NC_008253.1 932968 934083 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 932968..934083 Escherichia coli 536 4191824 YP_668810.1 CDS ECP_0894 NC_008253.1 934080 936026 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 934080..936026 Escherichia coli 536 4191825 YP_668811.1 CDS ECP_0895 NC_008253.1 936099 936323 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(936099..936323) Escherichia coli 536 4191826 YP_668812.1 CDS clpS NC_008253.1 936646 936966 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 936646..936966 Escherichia coli 536 4191827 YP_668813.1 CDS clpA NC_008253.1 936997 939273 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 936997..939273 Escherichia coli 536 4191828 YP_668814.1 CDS infA NC_008253.1 940017 940235 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(940017..940235) Escherichia coli 536 4191829 YP_668815.1 CDS aat NC_008253.1 940520 941224 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(940520..941224) Escherichia coli 536 4191830 YP_668816.1 CDS ECP_0900 NC_008253.1 941266 942987 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(941266..942987) Escherichia coli 536 4191831 YP_668817.1 CDS ECP_0901 NC_008253.1 942988 944754 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(942988..944754) Escherichia coli 536 4191832 YP_668818.1 CDS ECP_0902 NC_008253.1 944877 945842 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(944877..945842) Escherichia coli 536 4191833 YP_668819.1 CDS ECP_0903 NC_008253.1 946335 946880 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 946335..946880 Escherichia coli 536 4191834 YP_668820.1 CDS ECP_0904 NC_008253.1 947015 950995 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 947015..950995 Escherichia coli 536 4191835 YP_668821.1 CDS lolA NC_008253.1 951151 951765 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 951151..951765 Escherichia coli 536 4191836 YP_668822.1 CDS ECP_0906 NC_008253.1 951776 953119 D recombination factor protein RarA 951776..953119 Escherichia coli 536 4191837 YP_668823.1 CDS ECP_0907 NC_008253.1 953210 954502 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 953210..954502 Escherichia coli 536 4187489 YP_668824.1 CDS ECP_0908 NC_008253.1 954741 957185 D anaerobic dimethyl sulfoxide reductase subunit A 954741..957185 Escherichia coli 536 4187490 YP_668825.1 CDS ECP_0909 NC_008253.1 957196 957813 D anaerobic dimethyl sulfoxide reductase subunit B 957196..957813 Escherichia coli 536 4187491 YP_668826.1 CDS ECP_0910 NC_008253.1 957815 958678 D anaerobic dimethyl sulfoxide reductase subunit C 957815..958678 Escherichia coli 536 4187492 YP_668827.1 CDS ECP_0911 NC_008253.1 958714 959340 R hydrolase; hypothetical protein complement(958714..959340) Escherichia coli 536 4187493 YP_668828.1 CDS ECP_0912 NC_008253.1 959654 960802 D MFS family transporter protein 959654..960802 Escherichia coli 536 4187494 YP_668829.1 CDS pflA NC_008253.1 960899 961639 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(960899..961639) Escherichia coli 536 4187495 YP_668830.1 CDS ECP_0914 NC_008253.1 961831 964113 R formate acetyltransferase 1 complement(961831..964113) Escherichia coli 536 4187496 YP_668831.1 CDS ECP_0915 NC_008253.1 964168 965364 R formate transporter complement(964168..965364) Escherichia coli 536 4187497 YP_668832.1 CDS ECP_0916 NC_008253.1 965431 967191 R hypothetical protein complement(965431..967191) Escherichia coli 536 4187498 YP_668833.1 CDS ECP_0917 NC_008253.1 967321 968013 D membrane protein YcaP 967321..968013 Escherichia coli 536 4187499 YP_668834.1 CDS ECP_0918 NC_008253.1 968212 969300 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 968212..969300 Escherichia coli 536 4187500 YP_668835.1 CDS ECP_0919 NC_008253.1 969371 970654 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 969371..970654 Escherichia coli 536 4187501 YP_668836.1 CDS ECP_0920 NC_008253.1 970815 971588 D metalloprotease YcaL 970815..971588 Escherichia coli 536 4187502 YP_668837.1 CDS cmk NC_008253.1 971761 972444 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 971761..972444 Escherichia coli 536 4187503 YP_668838.1 CDS rpsA NC_008253.1 972555 974228 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 972555..974228 Escherichia coli 536 4187504 YP_668839.1 CDS ihfB NC_008253.1 974388 974672 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 974388..974672 Escherichia coli 536 4187505 YP_668840.1 CDS ECP_0924 NC_008253.1 974878 977142 D competence-related protein; hypothetical protein 974878..977142 Escherichia coli 536 4187506 YP_668841.1 CDS ECP_0925 NC_008253.1 977179 978927 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 977179..978927 Escherichia coli 536 4187507 YP_668842.1 CDS lpxK NC_008253.1 978924 979910 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 978924..979910 Escherichia coli 536 4187508 YP_668843.1 CDS ECP_0927 NC_008253.1 979947 981179 D hypothetical protein 979947..981179 Escherichia coli 536 4191592 YP_668844.1 CDS ECP_0928 NC_008253.1 981231 981413 D hypothetical protein 981231..981413 Escherichia coli 536 4191593 YP_668845.1 CDS ECP_0929 NC_008253.1 981410 982156 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 981410..982156 Escherichia coli 536 4191594 YP_668846.1 CDS ECP_0930 NC_008253.1 982310 983203 D hypothetical protein 982310..983203 Escherichia coli 536 4191595 YP_668847.1 CDS ECP_0931 NC_008253.1 983180 983959 R hypothetical protein complement(983180..983959) Escherichia coli 536 4191596 YP_668848.1 CDS ECP_0932 NC_008253.1 984095 984880 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 984095..984880 Escherichia coli 536 4191597 YP_668849.1 CDS ECP_0933 NC_008253.1 984877 986199 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 984877..986199 Escherichia coli 536 4191598 YP_668850.1 CDS ECP_0934 NC_008253.1 986180 986884 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 986180..986884 Escherichia coli 536 4191599 YP_668851.1 CDS mukB NC_008253.1 986884 991344 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 986884..991344 Escherichia coli 536 4191600 YP_668852.1 CDS ECP_0936 NC_008253.1 991605 993452 D hypothetical protein 991605..993452 Escherichia coli 536 4191601 YP_668853.1 CDS ECP_0937 NC_008253.1 993634 994182 D exported protein YcbK 993634..994182 Escherichia coli 536 4191602 YP_668854.1 CDS ECP_0938 NC_008253.1 994209 994856 D metallo-beta-lactamase; hypothetical protein 994209..994856 Escherichia coli 536 4191603 YP_668855.1 CDS ECP_0939 NC_008253.1 994906 996096 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(994906..996096) Escherichia coli 536 4191604 YP_668856.1 CDS ECP_0940 NC_008253.1 996281 997369 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(996281..997369) Escherichia coli 536 4191605 YP_668857.1 CDS asnC NC_008253.1 997973 999373 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(997973..999373) Escherichia coli 536 4191606 YP_668858.1 CDS pepN NC_008253.1 1001009 1003621 D aminopeptidase 1001009..1003621 Escherichia coli 536 4187433 YP_668859.1 CDS ssuB NC_008253.1 1003815 1004582 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1003815..1004582) Escherichia coli 536 4187434 YP_668860.1 CDS ssuC NC_008253.1 1004579 1005370 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease complement(1004579..1005370) Escherichia coli 536 4187435 YP_668861.1 CDS ECP_0947 NC_008253.1 1005382 1006527 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1005382..1006527) Escherichia coli 536 4187436 YP_668862.1 CDS ECP_0948 NC_008253.1 1006524 1007483 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1006524..1007483) Escherichia coli 536 4187437 YP_668863.1 CDS ECP_0949 NC_008253.1 1007476 1008051 R NAD(P)H-dependent FMN reductase complement(1007476..1008051) Escherichia coli 536 4187438 YP_668864.1 CDS ECP_0950 NC_008253.1 1008288 1009298 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1008288..1009298 Escherichia coli 536 4187439 YP_668865.1 CDS ECP_0951 NC_008253.1 1009472 1010014 D hypothetical protein 1009472..1010014 Escherichia coli 536 4187440 YP_668866.1 CDS ECP_0952 NC_008253.1 1010011 1011120 R iron-sulfur binding protein; hypothetical protein complement(1010011..1011120) Escherichia coli 536 4187441 YP_668867.1 CDS rlmL NC_008253.1 1011218 1013326 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1011218..1013326 Escherichia coli 536 4187442 YP_668868.1 CDS ECP_0954 NC_008253.1 1013338 1015245 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1013338..1015245 Escherichia coli 536 4187443 YP_668869.1 CDS ECP_0955 NC_008253.1 1015375 1016628 D inner membrane protein; paraquat-inducible protein A 1015375..1016628 Escherichia coli 536 4187444 YP_668870.1 CDS ECP_0956 NC_008253.1 1016633 1018273 D paraquat-inducible protein B 1016633..1018273 Escherichia coli 536 4187445 YP_668871.1 CDS ECP_0957 NC_008253.1 1018270 1018833 D hypothetical protein 1018270..1018833 Escherichia coli 536 4187446 YP_668872.1 CDS ECP_0958 NC_008253.1 1019089 1019256 D ribosome modulation factor 1019089..1019256 Escherichia coli 536 4187447 YP_668873.2 CDS ECP_0959 NC_008253.1 1019326 1019844 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1019326..1019844) Escherichia coli 536 4187448 YP_668874.1 CDS ECP_0960 NC_008253.1 1019913 1021673 R protease La complement(1019913..1021673) Escherichia coli 536 4187449 YP_668875.1 CDS ECP_0961 NC_008253.1 1021859 1022311 D hypothetical protein 1021859..1022311 Escherichia coli 536 4187450 YP_668876.1 CDS ECP_0962 NC_008253.1 1022387 1023427 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1022387..1023427) Escherichia coli 536 4187451 YP_668877.1 CDS ECP_0963 NC_008253.1 1023629 1023799 D hypothetical protein 1023629..1023799 Escherichia coli 536 4190177 YP_668878.1 CDS ECP_0964 NC_008253.1 1023783 1024292 R SOS cell division inhibitor complement(1023783..1024292) Escherichia coli 536 4190178 YP_668879.1 CDS ECP_0965 NC_008253.1 1024511 1025140 D hypothetical protein 1024511..1025140 Escherichia coli 536 4190179 YP_668880.1 CDS ECP_0966 NC_008253.1 1025103 1027265 R membrane protein YccS complement(1025103..1027265) Escherichia coli 536 4190180 YP_668881.1 CDS ECP_0967 NC_008253.1 1027275 1027721 R hypothetical protein complement(1027275..1027721) Escherichia coli 536 4190181 YP_668882.1 CDS helD NC_008253.1 1027751 1029898 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1027751..1029898 Escherichia coli 536 4190182 YP_668883.1 CDS mgsA NC_008253.1 1029930 1030397 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1029930..1030397) Escherichia coli 536 4190183 YP_668884.1 CDS ECP_0970 NC_008253.1 1030484 1031146 R hypothetical protein complement(1030484..1031146) Escherichia coli 536 4190184 YP_668885.1 CDS ECP_0971 NC_008253.1 1031319 1031732 D succinyl-CoA synthetase; hypothetical protein 1031319..1031732 Escherichia coli 536 4190185 YP_668886.1 CDS ECP_0972 NC_008253.1 1031777 1032145 R hypothetical protein complement(1031777..1032145) Escherichia coli 536 4190186 YP_668887.1 CDS ECP_0973 NC_008253.1 1032152 1033342 R hypothetical protein complement(1032152..1033342) Escherichia coli 536 4190187 YP_668888.1 CDS ECP_0974 NC_008253.1 1033437 1033715 D acylphosphatase 1033437..1033715 Escherichia coli 536 4190188 YP_668889.1 CDS ECP_0975 NC_008253.1 1033712 1034041 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1033712..1034041) Escherichia coli 536 4190189 YP_668890.1 CDS ECP_0976 NC_008253.1 1034133 1034792 R hypothetical protein complement(1034133..1034792) Escherichia coli 536 4190190 YP_668891.1 CDS ECP_0977 NC_008253.1 1035513 1036631 D hydrogenase-1 small chain 1035513..1036631 Escherichia coli 536 4190191 YP_668892.1 CDS ECP_0978 NC_008253.1 1036628 1038421 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1036628..1038421 Escherichia coli 536 4190192 YP_668893.1 CDS ECP_0979 NC_008253.1 1038440 1039147 D hydrogenase 1 b-type cytochrome subunit 1038440..1039147 Escherichia coli 536 4190193 YP_668894.1 CDS ECP_0980 NC_008253.1 1039144 1039731 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1039144..1039731 Escherichia coli 536 4190194 YP_668895.1 CDS ECP_0981 NC_008253.1 1039728 1040126 D involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1039728..1040126 Escherichia coli 536 4190195 YP_668896.1 CDS ECP_0982 NC_008253.1 1040123 1040980 D hydrogenase-1 operon protein HyaF 1040123..1040980 Escherichia coli 536 4190196 YP_668897.1 CDS ECP_0983 NC_008253.1 1041114 1042658 D cytochrome bd-II oxidase subunit I 1041114..1042658 Escherichia coli 536 4187793 YP_668898.1 CDS ECP_0984 NC_008253.1 1042670 1043806 D cytochrome bd-II oxidase subunit II 1042670..1043806 Escherichia coli 536 4187794 YP_668899.1 CDS ECP_0985 NC_008253.1 1043961 1045301 D phosphoanhydride phosphorylase 1043961..1045301 Escherichia coli 536 4187795 YP_668900.1 CDS ECP_0986 NC_008253.1 1045289 1045501 R cold shock-like protein CspH complement(1045289..1045501) Escherichia coli 536 4187796 YP_668901.1 CDS ECP_0987 NC_008253.1 1045787 1045999 D cold shock protein CspG 1045787..1045999 Escherichia coli 536 4187797 YP_668902.1 CDS ECP_0988 NC_008253.1 1045965 1046198 D hypothetical protein 1045965..1046198 Escherichia coli 536 4187798 YP_668903.1 CDS ECP_0989 NC_008253.1 1046393 1046566 D hypothetical protein 1046393..1046566 Escherichia coli 536 4187799 YP_668904.1 CDS ECP_0990 NC_008253.1 1046615 1047688 R electron transport protein YccM complement(1046615..1047688) Escherichia coli 536 4187800 YP_668905.1 CDS ECP_0991 NC_008253.1 1047771 1050503 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1047771..1050503) Escherichia coli 536 4187801 YP_668906.1 CDS ECP_0992 NC_008253.1 1050586 1051614 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1050586..1051614 Escherichia coli 536 4187802 YP_668907.1 CDS ECP_0993 NC_008253.1 1051587 1052279 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1051587..1052279) Escherichia coli 536 4187803 YP_668908.1 CDS ECP_0994 NC_008253.1 1052409 1053581 D cytochrome c-type protein TorC 1052409..1053581 Escherichia coli 536 4187804 YP_668909.1 CDS ECP_0995 NC_008253.1 1053581 1056127 D trimethylamine-N-oxide reductase 1 1053581..1056127 Escherichia coli 536 4187805 YP_668910.1 CDS torD NC_008253.1 1056124 1056723 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1056124..1056723 Escherichia coli 536 4187806 YP_668911.1 CDS ECP_0997 NC_008253.1 1056806 1057327 D insertion element (orfA) 1056806..1057327 Escherichia coli 536 4187807 YP_668912.1 CDS ECP_0998 NC_008253.1 1057552 1058154 D insertion element (orfB) 1057552..1058154 Escherichia coli 536 4187808 YP_668913.1 CDS ECP_0999 NC_008253.1 1058413 1058718 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1058413..1058718) Escherichia coli 536 4187809 YP_668914.1 CDS ECP_1000 NC_008253.1 1058718 1059638 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1058718..1059638) Escherichia coli 536 4187810 YP_668915.1 CDS ECP_1001 NC_008253.1 1060173 1061414 D glucose-1-phosphatase/inositol phosphatase 1060173..1061414 Escherichia coli 536 4187811 YP_668916.1 CDS ECP_1002 NC_008253.1 1061452 1061679 R hypothetical protein complement(1061452..1061679) Escherichia coli 536 4187773 YP_668917.1 CDS ECP_1003 NC_008253.1 1061700 1062296 R Trp repressor binding protein; stationary phase that binds TrpR repressor; TrpR binding protein WrbA complement(1061700..1062296) Escherichia coli 536 4187774 YP_668918.1 CDS ECP_1004 NC_008253.1 1062669 1062842 D hypothetical protein 1062669..1062842 Escherichia coli 536 4187775 YP_668919.1 CDS ECP_1005 NC_008253.1 1062925 1064253 R purine permease; transporter complement(1062925..1064253) Escherichia coli 536 4187776 YP_668920.1 CDS ECP_1006 NC_008253.1 1064274 1064768 R flavin:NADH reductase YcdH complement(1064274..1064768) Escherichia coli 536 4187777 YP_668921.1 CDS ECP_1007 NC_008253.1 1064779 1065369 R hypothetical protein complement(1064779..1065369) Escherichia coli 536 4187778 YP_668922.1 CDS ECP_1008 NC_008253.1 1065379 1066179 R hydrolase; hypothetical protein complement(1065379..1066179) Escherichia coli 536 4187779 YP_668923.1 CDS ECP_1009 NC_008253.1 1066187 1066573 R hypothetical endoribonuclease; hypothetical protein complement(1066187..1066573) Escherichia coli 536 4187780 YP_668924.1 CDS ECP_1010 NC_008253.1 1066585 1067277 R isochorismatase YcdL complement(1066585..1067277) Escherichia coli 536 4187781 YP_668925.1 CDS ECP_1011 NC_008253.1 1067277 1068368 R monooxygenase YcdM complement(1067277..1068368) Escherichia coli 536 4187782 YP_668926.1 CDS ECP_1012 NC_008253.1 1068655 1069293 D TetR family transcriptional regulator 1068655..1069293 Escherichia coli 536 4187783 YP_668927.1 CDS putA NC_008253.1 1069333 1073295 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1069333..1073295) Escherichia coli 536 4187784 YP_668928.1 CDS ECP_1014 NC_008253.1 1073353 1073559 D hypothetical protein 1073353..1073559 Escherichia coli 536 4187785 YP_668929.1 CDS ECP_1015 NC_008253.1 1073718 1075226 D sodium/proline symporter 1073718..1075226 Escherichia coli 536 4187786 YP_668930.1 CDS ECP_1016 NC_008253.1 1075446 1076276 D iron permease; hypothetical protein 1075446..1076276 Escherichia coli 536 4187787 YP_668931.1 CDS ECP_1017 NC_008253.1 1076334 1077461 D hypothetical protein 1076334..1077461 Escherichia coli 536 4187788 YP_668932.1 CDS ECP_1018 NC_008253.1 1077467 1078738 D hypothetical protein 1077467..1078738 Escherichia coli 536 4187789 YP_668933.1 CDS ECP_1019 NC_008253.1 1079089 1080153 D hypothetical protein 1079089..1080153 Escherichia coli 536 4187790 YP_668934.1 CDS ECP_1020 NC_008253.1 1080203 1080616 R hypothetical protein complement(1080203..1080616) Escherichia coli 536 4187791 YP_668935.1 CDS ECP_1021 NC_008253.1 1080618 1081856 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; N-glycosyltransferase PgaC complement(1080618..1081856) Escherichia coli 536 4187792 YP_668936.1 CDS ECP_1022 NC_008253.1 1081936 1083954 R lipoprotein YcdR complement(1081936..1083954) Escherichia coli 536 4189411 YP_668937.1 CDS pgaA NC_008253.1 1083963 1086386 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1083963..1086386) Escherichia coli 536 4189412 YP_668938.1 CDS ECP_1024 NC_008253.1 1086973 1088340 D hypothetical protein 1086973..1088340 Escherichia coli 536 4189413 YP_668939.1 CDS ECP_1025 NC_008253.1 1088765 1089703 D 2-hydroxyacid dehydrogenase 1088765..1089703 Escherichia coli 536 4189414 YP_668940.1 CDS ECP_1026 NC_008253.1 1089758 1090495 D histidinol phosphatase and related hydrolases of the PHP family; hydrolase 1089758..1090495 Escherichia coli 536 4189415 YP_668941.1 CDS ECP_1027 NC_008253.1 1090519 1091073 D hypothetical protein 1090519..1091073 Escherichia coli 536 4189416 YP_668942.1 CDS ECP_1028 NC_008253.1 1091144 1091665 D hypothetical protein 1091144..1091665 Escherichia coli 536 4189417 YP_668943.1 CDS ECP_1029 NC_008253.1 1091729 1092415 R curli production assembly/transport component CsgG complement(1091729..1092415) Escherichia coli 536 4189418 YP_668944.1 CDS ECP_1030 NC_008253.1 1092590 1093006 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1092590..1093006) Escherichia coli 536 4189419 YP_668945.1 CDS ECP_1031 NC_008253.1 1093031 1093420 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1093031..1093420) Escherichia coli 536 4189420 YP_668946.1 CDS ECP_1032 NC_008253.1 1093425 1094075 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1093425..1094075) Escherichia coli 536 4189421 YP_668947.1 CDS ECP_1033 NC_008253.1 1094487 1094735 R hypothetical protein complement(1094487..1094735) Escherichia coli 536 4189422 YP_668948.1 CDS ECP_1034 NC_008253.1 1094829 1095284 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1094829..1095284 Escherichia coli 536 4189423 YP_668949.1 CDS ECP_1035 NC_008253.1 1095325 1095783 D cryptic curlin major subunit 1095325..1095783 Escherichia coli 536 4189424 YP_668950.1 CDS csgC NC_008253.1 1095842 1096174 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1095842..1096174 Escherichia coli 536 4189425 YP_668951.1 CDS ECP_1037 NC_008253.1 1096295 1096606 D hypothetical protein 1096295..1096606 Escherichia coli 536 4189426 YP_668952.1 CDS ECP_1038 NC_008253.1 1096701 1097234 D hypothetical protein 1096701..1097234 Escherichia coli 536 4189427 YP_668953.1 CDS ECP_1039 NC_008253.1 1097176 1098657 D hypothetical protein 1097176..1098657 Escherichia coli 536 4189428 YP_668954.1 CDS mdoC NC_008253.1 1098665 1099822 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1098665..1099822) Escherichia coli 536 4189429 YP_668955.1 CDS mdoG NC_008253.1 1100216 1101751 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1100216..1101751 Escherichia coli 536 4189698 YP_668956.1 CDS ECP_1042 NC_008253.1 1101744 1104287 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1101744..1104287 Escherichia coli 536 4189699 YP_668957.1 CDS ECP_1043 NC_008253.1 1104296 1104520 D hypothetical protein 1104296..1104520 Escherichia coli 536 4189700 YP_668958.1 CDS ECP_1044 NC_008253.1 1104459 1104686 D hypothetical protein 1104459..1104686 Escherichia coli 536 4189701 YP_668959.1 CDS ECP_1045 NC_008253.1 1104687 1105061 R hypothetical protein complement(1104687..1105061) Escherichia coli 536 4189702 YP_668960.1 CDS ECP_1046 NC_008253.1 1105144 1106370 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1105144..1106370) Escherichia coli 536 4189703 YP_668961.1 CDS ECP_1047 NC_008253.1 1106542 1107462 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1106542..1107462) Escherichia coli 536 4189704 YP_668962.1 CDS ECP_1048 NC_008253.1 1107687 1108739 D hypothetical protein 1107687..1108739 Escherichia coli 536 4189705 YP_668963.1 CDS ECP_1049 NC_008253.1 1108781 1109356 R secreted protein; hypothetical protein complement(1108781..1109356) Escherichia coli 536 4189706 YP_668964.1 CDS ECP_1050 NC_008253.1 1109360 1109926 R cytochrome b561-like protein 2 complement(1109360..1109926) Escherichia coli 536 4189707 YP_668965.1 CDS solA NC_008253.1 1110348 1111466 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1110348..1111466) Escherichia coli 536 4189708 YP_668966.1 CDS bssS NC_008253.1 1111581 1111835 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1111581..1111835) Escherichia coli 536 4189709 YP_668967.1 CDS ECP_1053 NC_008253.1 1112125 1112370 R DNA damage-inducible protein I complement(1112125..1112370) Escherichia coli 536 4189710 YP_668968.1 CDS ECP_1054 NC_008253.1 1112444 1113490 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1112444..1113490) Escherichia coli 536 4189711 YP_668969.1 CDS ECP_1055 NC_008253.1 1113596 1114156 R hypothetical protein complement(1113596..1114156) Escherichia coli 536 4189712 YP_668970.1 CDS ECP_1056 NC_008253.1 1114290 1114937 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1114290..1114937) Escherichia coli 536 4189713 YP_668971.1 CDS ECP_1057 NC_008253.1 1115001 1116209 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1115001..1116209) Escherichia coli 536 4189714 YP_668972.1 CDS ECP_1058 NC_008253.1 1116445 1117029 D ribosomal-protein-S5-alanine N-acetyltransferase 1116445..1117029 Escherichia coli 536 4189715 YP_668973.1 CDS ECP_1059 NC_008253.1 1117040 1117687 D hypothetical protein 1117040..1117687 Escherichia coli 536 4189716 YP_668974.1 CDS ECP_1060 NC_008253.1 1117689 1118612 D virulence factor MviM 1117689..1118612 Escherichia coli 536 4189717 YP_668975.1 CDS ECP_1061 NC_008253.1 1118722 1120257 D virulence factor mviN-like protein 1118722..1120257 Escherichia coli 536 4187603 YP_668976.1 CDS ECP_1062 NC_008253.1 1120297 1120713 R flagellar synthesis protein FlgN complement(1120297..1120713) Escherichia coli 536 4187604 YP_668977.1 CDS ECP_1063 NC_008253.1 1120718 1121011 R regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1120718..1121011) Escherichia coli 536 4187605 YP_668978.1 CDS flgA NC_008253.1 1121087 1121746 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1121087..1121746) Escherichia coli 536 4187606 YP_668979.1 CDS flgB NC_008253.1 1121901 1122317 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1121901..1122317 Escherichia coli 536 4187607 YP_668980.1 CDS flgC NC_008253.1 1122321 1122725 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1122321..1122725 Escherichia coli 536 4187608 YP_668981.1 CDS flgD NC_008253.1 1122737 1123432 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1122737..1123432 Escherichia coli 536 4187609 YP_668982.1 CDS flgE NC_008253.1 1123457 1124662 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1123457..1124662 Escherichia coli 536 4187610 YP_668983.1 CDS flgF NC_008253.1 1124682 1125437 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1124682..1125437 Escherichia coli 536 4187611 YP_668984.1 CDS flgG NC_008253.1 1125609 1126391 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1125609..1126391 Escherichia coli 536 4187612 YP_668985.1 CDS flgH NC_008253.1 1126435 1127142 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1126435..1127142 Escherichia coli 536 4187613 YP_668986.1 CDS flgI NC_008253.1 1127154 1128251 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1127154..1128251 Escherichia coli 536 4187614 YP_668987.2 CDS flgJ NC_008253.1 1128251 1129192 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1128251..1129192 Escherichia coli 536 4187615 YP_668988.1 CDS flgK NC_008253.1 1129258 1130901 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1129258..1130901 Escherichia coli 536 4187616 YP_668989.1 CDS flgL NC_008253.1 1130913 1131866 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1130913..1131866 Escherichia coli 536 4187617 YP_668990.1 CDS rne NC_008253.1 1132061 1135246 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1132061..1135246) Escherichia coli 536 4187618 YP_668991.1 CDS ECP_1077 NC_008253.1 1135381 1135701 D hypothetical protein 1135381..1135701 Escherichia coli 536 4187619 YP_668992.1 CDS ECP_1078 NC_008253.1 1135819 1136778 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1135819..1136778 Escherichia coli 536 4187620 YP_668993.1 CDS ECP_1079 NC_008253.1 1136890 1137513 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1136890..1137513) Escherichia coli 536 4187621 YP_668994.1 CDS ECP_1080 NC_008253.1 1137673 1138194 D hypothetical protein 1137673..1138194 Escherichia coli 536 4187284 YP_668995.1 CDS rpmF NC_008253.1 1138246 1138419 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1138246..1138419 Escherichia coli 536 4187285 YP_668996.1 CDS ECP_1082 NC_008253.1 1138500 1139570 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1138500..1139570 Escherichia coli 536 4187286 YP_668997.1 CDS ECP_1083 NC_008253.1 1139638 1140591 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1139638..1140591 Escherichia coli 536 4187287 YP_668998.1 CDS ECP_1084 NC_008253.1 1140607 1141536 D malonyl CoA-acyl carrier protein transacylase 1140607..1141536 Escherichia coli 536 4187288 YP_668999.1 CDS fabG NC_008253.1 1141549 1142283 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1141549..1142283 Escherichia coli 536 4187289 YP_669000.1 CDS acpP NC_008253.1 1142494 1142730 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1142494..1142730 Escherichia coli 536 4187290 YP_669001.1 CDS ECP_1087 NC_008253.1 1142817 1144058 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1142817..1144058 Escherichia coli 536 4187291 YP_669002.1 CDS ECP_1088 NC_008253.1 1144178 1144987 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1144178..1144987 Escherichia coli 536 4187292 YP_669003.1 CDS ECP_1089 NC_008253.1 1144990 1146012 D 4-amino-4-deoxychorismate lyase; hypothetical protein 1144990..1146012 Escherichia coli 536 4187293 YP_669004.1 CDS tmk NC_008253.1 1146002 1146643 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1146002..1146643 Escherichia coli 536 4187294 YP_669005.1 CDS ECP_1091 NC_008253.1 1146640 1147644 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1146640..1147644 Escherichia coli 536 4187295 YP_669006.1 CDS ECP_1092 NC_008253.1 1147655 1148452 D metallodependent hydrolase 1147655..1148452 Escherichia coli 536 4187296 YP_669007.1 CDS ECP_1093 NC_008253.1 1148747 1150180 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; glucose-specific PTS system IIBC components 1148747..1150180 Escherichia coli 536 4187297 YP_669008.1 CDS ECP_1094 NC_008253.1 1150240 1152219 R ferric-rhodotorulic acid outer membrane transporter complement(1150240..1152219) Escherichia coli 536 4187298 YP_669009.1 CDS ECP_1095 NC_008253.1 1152764 1153123 D purine nucleoside phosphoramidase 1152764..1153123 Escherichia coli 536 4187299 YP_669010.1 CDS ECP_1096 NC_008253.1 1153126 1153503 D outer membrane lipoprotein YcfL 1153126..1153503 Escherichia coli 536 4187300 YP_669011.1 CDS ECP_1097 NC_008253.1 1153517 1154158 D hypothetical protein 1153517..1154158 Escherichia coli 536 4187301 YP_669012.1 CDS thiK NC_008253.1 1154139 1154963 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1154139..1154963 Escherichia coli 536 4187302 YP_669013.1 CDS ECP_1099 NC_008253.1 1154986 1155999 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1154986..1155999 Escherichia coli 536 4187303 YP_669014.1 CDS ECP_1100 NC_008253.1 1156022 1156564 D hypothetical protein 1156022..1156564 Escherichia coli 536 4190820 YP_669015.1 CDS ECP_1101 NC_008253.1 1156964 1158268 D NADH dehydrogenase 1156964..1158268 Escherichia coli 536 4190821 YP_669016.1 CDS ECP_1102 NC_008253.1 1158495 1159034 D hypothetical protein 1158495..1159034 Escherichia coli 536 4190822 YP_669017.1 CDS ECP_1103 NC_008253.1 1159096 1159728 R TetR family regulatory protein complement(1159096..1159728) Escherichia coli 536 4190823 YP_669018.1 CDS ECP_1104 NC_008253.1 1159969 1160226 D hypothetical protein 1159969..1160226 Escherichia coli 536 4190824 YP_669019.1 CDS ECP_1105 NC_008253.1 1160309 1161268 R hypothetical protein complement(1160309..1161268) Escherichia coli 536 4190825 YP_669020.1 CDS ECP_1106 NC_008253.1 1161416 1164910 R transcription-repair coupling factor complement(1161416..1164910) Escherichia coli 536 4190826 YP_669021.1 CDS ECP_1107 NC_008253.1 1164990 1165337 R similart to the C-terminal part of the hypothetical protein YcfT; hypothetical protein complement(1164990..1165337) Escherichia coli 536 4190827 YP_669022.1 CDS ECP_1108 NC_008253.1 1165359 1166063 R similar to the N-terminal part of the hypothetical protein YcfT; hypothetical protein complement(1165359..1166063) Escherichia coli 536 4190828 YP_669023.1 CDS ECP_1109 NC_008253.1 1166325 1167524 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1166325..1167524 Escherichia coli 536 4190829 YP_669024.1 CDS lolD NC_008253.1 1167574 1168218 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1167574..1168218 Escherichia coli 536 4190830 YP_669025.1 CDS ECP_1113 NC_008253.1 1169492 1170403 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1169492..1170403 Escherichia coli 536 4190833 YP_669026.1 CDS ECP_1114 NC_008253.1 1170419 1171240 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1170419..1171240 Escherichia coli 536 4190834 YP_669027.1 CDS ECP_1115 NC_008253.1 1171377 1172162 R hypothetical protein complement(1171377..1172162) Escherichia coli 536 4190835 YP_669028.1 CDS ECP_1116 NC_008253.1 1172159 1172620 R membrane protein YmfA complement(1172159..1172620) Escherichia coli 536 4190836 YP_669029.1 CDS potD NC_008253.1 1172678 1173724 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1172678..1173724) Escherichia coli 536 4187470 YP_669030.1 CDS potC NC_008253.1 1173721 1174515 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1173721..1174515) Escherichia coli 536 4187471 YP_669031.1 CDS potB NC_008253.1 1174512 1175369 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1174512..1175369) Escherichia coli 536 4187472 YP_669032.1 CDS potA NC_008253.1 1175353 1176489 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1175353..1176489) Escherichia coli 536 4187473 YP_669033.1 CDS ECP_1121 NC_008253.1 1176468 1176683 R hypothetical protein complement(1176468..1176683) Escherichia coli 536 4187474 YP_669034.1 CDS ECP_1122 NC_008253.1 1176739 1177965 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1176739..1177965 Escherichia coli 536 4187475 YP_669035.1 CDS ECP_1123 NC_008253.1 1178014 1179144 R hypothetical protein complement(1178014..1179144) Escherichia coli 536 4187476 YP_669036.1 CDS ECP_1124 NC_008253.1 1179211 1180671 R sensor protein PhoQ complement(1179211..1180671) Escherichia coli 536 4187477 YP_669037.1 CDS ECP_1125 NC_008253.1 1180671 1181342 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1180671..1181342) Escherichia coli 536 4187478 YP_669038.1 CDS ECP_1126 NC_008253.1 1181512 1182882 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1181512..1182882) Escherichia coli 536 4187479 YP_669039.1 CDS ECP_1127 NC_008253.1 1182886 1183533 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1182886..1183533) Escherichia coli 536 4187480 YP_669040.1 CDS mnmA NC_008253.1 1183563 1184669 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1183563..1184669) Escherichia coli 536 4187481 YP_669041.1 CDS ECP_1129 NC_008253.1 1184723 1185184 R nudix hydrolase YmfB complement(1184723..1185184) Escherichia coli 536 4187482 YP_669042.1 CDS ECP_1130 NC_008253.1 1185194 1185847 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1185194..1185847) Escherichia coli 536 4187483 YP_669043.1 CDS ECP_1131 NC_008253.1 1186019 1187269 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1186019..1187269 Escherichia coli 536 4187484 YP_669044.1 CDS ECP_1132 NC_008253.1 1187383 1187871 R hypothetical protein complement(1187383..1187871) Escherichia coli 536 4187485 YP_669045.1 CDS ECP_1133 NC_008253.1 1188067 1188846 R transposase/IS protein complement(1188067..1188846) Escherichia coli 536 4187486 YP_669046.1 CDS ECP_1134 NC_008253.1 1188846 1189868 R transposase for insertion sequence IS100 complement(1188846..1189868) Escherichia coli 536 4187487 YP_669047.1 CDS ECP_1135 NC_008253.1 1189882 1190484 R hypothetical protein complement(1189882..1190484) Escherichia coli 536 4187488 YP_669048.1 CDS ECP_1136 NC_008253.1 1190474 1190710 R excisionase complement(1190474..1190710) Escherichia coli 536 4188022 YP_669049.1 CDS ECP_1137 NC_008253.1 1190850 1191089 R hypothetical protein complement(1190850..1191089) Escherichia coli 536 4188023 YP_669050.1 CDS ECP_1138 NC_008253.1 1191137 1191355 R hypothetical protein complement(1191137..1191355) Escherichia coli 536 4188024 YP_669051.1 CDS ECP_1139 NC_008253.1 1191454 1191669 R hypothetical protein complement(1191454..1191669) Escherichia coli 536 4188025 YP_669052.1 CDS ECP_1140 NC_008253.1 1192089 1192769 R exonuclease complement(1192089..1192769) Escherichia coli 536 4188026 YP_669053.1 CDS ECP_1141 NC_008253.1 1192766 1193551 R bacteriophage recombination protein complement(1192766..1193551) Escherichia coli 536 4188027 YP_669054.1 CDS ECP_1142 NC_008253.1 1193557 1193853 R host-nuclease inhibitor protein Gam complement(1193557..1193853) Escherichia coli 536 4188028 YP_669055.1 CDS ECP_1143 NC_008253.1 1193928 1194314 R prophage Kil protein complement(1193928..1194314) Escherichia coli 536 4188029 YP_669056.1 CDS ECP_1144 NC_008253.1 1194610 1194987 R phage associated protein complement(1194610..1194987) Escherichia coli 536 4188030 YP_669057.1 CDS ECP_1145 NC_008253.1 1194965 1196026 R hypothetical protein complement(1194965..1196026) Escherichia coli 536 4188031 YP_669058.1 CDS ECP_1146 NC_008253.1 1196107 1196799 R regulatory protein CI; phage-related repressor protein complement(1196107..1196799) Escherichia coli 536 4188032 YP_669059.1 CDS ECP_1147 NC_008253.1 1196910 1197137 D hypothetical protein 1196910..1197137 Escherichia coli 536 4188033 YP_669060.1 CDS ECP_1148 NC_008253.1 1197162 1197707 D bacteriophage regulatory protein CII 1197162..1197707 Escherichia coli 536 4188034 YP_669061.1 CDS ECP_1149 NC_008253.1 1197704 1198723 D replication protein O 1197704..1198723 Escherichia coli 536 4188035 YP_669062.1 CDS ECP_1150 NC_008253.1 1198720 1199433 D replication protein 14 1198720..1199433 Escherichia coli 536 4188036 YP_669063.1 CDS ECP_1151 NC_008253.1 1199512 1199940 R hypothetical protein complement(1199512..1199940) Escherichia coli 536 4188037 YP_669064.1 CDS ECP_1152 NC_008253.1 1199937 1200314 R hypothetical protein complement(1199937..1200314) Escherichia coli 536 4188038 YP_669065.1 CDS ECP_1153 NC_008253.1 1200582 1201037 D DLP12 prophage; hypothetical protein 1200582..1201037 Escherichia coli 536 4188039 YP_669066.1 CDS ECP_1154 NC_008253.1 1201200 1201490 D hypothetical protein 1201200..1201490 Escherichia coli 536 4188040 YP_669067.1 CDS ECP_1155 NC_008253.1 1201487 1201849 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1201487..1201849 Escherichia coli 536 4188041 YP_669068.1 CDS ECP_1156 NC_008253.1 1202072 1202455 D antitermination protein Q 1202072..1202455 Escherichia coli 536 4191800 YP_669069.1 CDS ECP_1157 NC_008253.1 1202644 1203726 R outer membrane porin protein LC complement(1202644..1203726) Escherichia coli 536 4191801 YP_669070.1 CDS ECP_1158 NC_008253.1 1204055 1204204 D hypothetical protein 1204055..1204204 Escherichia coli 536 4191802 YP_669071.1 CDS ECP_1159 NC_008253.1 1204315 1204530 D lysis protein S 1204315..1204530 Escherichia coli 536 4191803 YP_669072.1 CDS ECP_1160 NC_008253.1 1204530 1205027 D lysozyme 1204530..1205027 Escherichia coli 536 4191804 YP_669073.1 CDS ECP_1161 NC_008253.1 1205024 1205485 D endopeptidase 1205024..1205485 Escherichia coli 536 4191805 YP_669074.1 CDS ECP_1162 NC_008253.1 1205517 1205810 R Bor protein complement(1205517..1205810) Escherichia coli 536 4191806 YP_669075.1 CDS ECP_1163 NC_008253.1 1206291 1206617 D may be prophage encoded; TonB-like membrane protein 1206291..1206617 Escherichia coli 536 4191807 YP_669076.1 CDS ECP_1164 NC_008253.1 1206824 1207006 D hypothetical protein 1206824..1207006 Escherichia coli 536 4191808 YP_669077.1 CDS ECP_1165 NC_008253.1 1207236 1207487 D hypothetical protein 1207236..1207487 Escherichia coli 536 4191809 YP_669078.1 CDS ECP_1166 NC_008253.1 1207569 1208114 D terminase small subunit 1207569..1208114 Escherichia coli 536 4191810 YP_669079.1 CDS ECP_1167 NC_008253.1 1208089 1210014 D terminase large subunit 1208089..1210014 Escherichia coli 536 4191811 YP_669080.1 CDS ECP_1168 NC_008253.1 1210011 1210217 D head-to-tail joining protein W 1210011..1210217 Escherichia coli 536 4191812 YP_669081.1 CDS ECP_1169 NC_008253.1 1210214 1211815 D minor capsid protein B 1210214..1211815 Escherichia coli 536 4191813 YP_669082.1 CDS ECP_1170 NC_008253.1 1211796 1213115 D minor capsid protein C 1211796..1213115 Escherichia coli 536 4191814 YP_669083.1 CDS ECP_1171 NC_008253.1 1213125 1213457 D major capsid protein D 1213125..1213457 Escherichia coli 536 4191815 YP_669084.1 CDS ECP_1172 NC_008253.1 1213513 1214538 D major coat protein 1213513..1214538 Escherichia coli 536 4191816 YP_669085.1 CDS ECP_1173 NC_008253.1 1214580 1214975 D DNA packaging protein FI 1214580..1214975 Escherichia coli 536 4191817 YP_669086.1 CDS ECP_1174 NC_008253.1 1214987 1215340 D tail attachment protein minor capsid protein FII) 1214987..1215340 Escherichia coli 536 4191818 YP_669087.1 CDS ECP_1175 NC_008253.1 1215352 1215930 D minor tail protein Z 1215352..1215930 Escherichia coli 536 4189104 YP_669088.1 CDS ECP_1176 NC_008253.1 1215927 1216322 D minor tail protein U 1215927..1216322 Escherichia coli 536 4189105 YP_669089.1 CDS ECP_1177 NC_008253.1 1216330 1217070 D major tail protein V 1216330..1217070 Escherichia coli 536 4189106 YP_669090.1 CDS ECP_1178 NC_008253.1 1217086 1217508 D minor tail protein G 1217086..1217508 Escherichia coli 536 4189107 YP_669091.1 CDS ECP_1179 NC_008253.1 1217490 1217924 D minor tail protein T 1217490..1217924 Escherichia coli 536 4189108 YP_669092.1 CDS ECP_1180 NC_008253.1 1217917 1220484 D minor tail protein H 1217917..1220484 Escherichia coli 536 4189109 YP_669093.1 CDS ECP_1181 NC_008253.1 1220481 1220810 D minor tail protein M 1220481..1220810 Escherichia coli 536 4189110 YP_669094.1 CDS ECP_1182 NC_008253.1 1220810 1221508 D minor tail protein L 1220810..1221508 Escherichia coli 536 4189111 YP_669095.1 CDS ECP_1183 NC_008253.1 1221514 1222257 D tail assembly protein K 1221514..1222257 Escherichia coli 536 4189112 YP_669096.1 CDS ECP_1184 NC_008253.1 1222155 1222826 D tail assembly protein I 1222155..1222826 Escherichia coli 536 4189113 YP_669097.1 CDS ECP_1185 NC_008253.1 1222887 1226369 D host specificity protein J 1222887..1226369 Escherichia coli 536 4189114 YP_669098.1 CDS ECP_1186 NC_008253.1 1226428 1228488 D tail fiber protein 1226428..1228488 Escherichia coli 536 4189115 YP_669099.1 CDS ECP_1187 NC_008253.1 1228485 1228763 D hypothetical protein 1228485..1228763 Escherichia coli 536 4189116 YP_669100.1 CDS ECP_1188 NC_008253.1 1228776 1229069 D hypothetical protein 1228776..1229069 Escherichia coli 536 4189117 YP_669101.1 CDS ECP_1189 NC_008253.1 1229161 1230018 R iron transport protein, inner membrane component complement(1229161..1230018) Escherichia coli 536 4189118 YP_669102.1 CDS ECP_1190 NC_008253.1 1230015 1230872 R iron transport protein, inner membrane component complement(1230015..1230872) Escherichia coli 536 4189119 YP_669103.1 CDS ECP_1191 NC_008253.1 1230869 1231696 R iron ABC transporter ATP-binding protein complement(1230869..1231696) Escherichia coli 536 4189120 YP_669104.1 CDS ECP_1192 NC_008253.1 1231696 1232610 R iron transport protein, periplasmic-binding protein complement(1231696..1232610) Escherichia coli 536 4189121 YP_669105.1 CDS ECP_1193 NC_008253.1 1232889 1233482 D acetyltransferase 1232889..1233482 Escherichia coli 536 4189122 YP_669106.1 CDS ECP_1194 NC_008253.1 1233737 1234321 D transcriptional regulator 1233737..1234321 Escherichia coli 536 4189123 YP_669107.1 CDS ECP_1195 NC_008253.1 1234346 1234783 R hypothetical protein complement(1234346..1234783) Escherichia coli 536 4189012 YP_669108.1 CDS ECP_1196 NC_008253.1 1235057 1235224 R hypothetical protein complement(1235057..1235224) Escherichia coli 536 4189013 YP_669109.1 CDS ECP_1197 NC_008253.1 1235263 1235415 D hypothetical protein 1235263..1235415 Escherichia coli 536 4189014 YP_669110.1 CDS ECP_1198 NC_008253.1 1235677 1236081 R hypothetical protein complement(1235677..1236081) Escherichia coli 536 4189015 YP_669111.1 CDS ECP_1199 NC_008253.1 1236302 1237033 R transcriptional regulator YcgE complement(1236302..1237033) Escherichia coli 536 4189016 YP_669112.1 CDS ECP_1200 NC_008253.1 1237238 1238449 R hypothetical protein complement(1237238..1238449) Escherichia coli 536 4189017 YP_669113.1 CDS ECP_1201 NC_008253.1 1238763 1238999 D hypothetical protein 1238763..1238999 Escherichia coli 536 4189018 YP_669114.1 CDS ECP_1202 NC_008253.1 1239042 1239314 D hypothetical protein 1239042..1239314 Escherichia coli 536 4189019 YP_669115.1 CDS ECP_1203 NC_008253.1 1239343 1239609 D hypothetical protein 1239343..1239609 Escherichia coli 536 4189020 YP_669116.1 CDS ECP_1204 NC_008253.1 1239722 1239970 D hypothetical protein 1239722..1239970 Escherichia coli 536 4189021 YP_669117.1 CDS ECP_1205 NC_008253.1 1240310 1241161 D hypothetical protein 1240310..1241161 Escherichia coli 536 4189022 YP_669118.1 CDS ECP_1206 NC_008253.1 1241257 1241511 D hypothetical protein 1241257..1241511 Escherichia coli 536 4189023 YP_669119.1 CDS ECP_1207 NC_008253.1 1241909 1242088 D hypothetical protein 1241909..1242088 Escherichia coli 536 4189024 YP_669120.1 CDS ECP_1208 NC_008253.1 1242378 1242755 D hypothetical protein 1242378..1242755 Escherichia coli 536 4189025 YP_669121.1 CDS ECP_1209 NC_008253.1 1242901 1243428 D hypothetical protein 1242901..1243428 Escherichia coli 536 4189026 YP_669122.1 CDS ECP_1210 NC_008253.1 1243486 1243815 R hypothetical protein complement(1243486..1243815) Escherichia coli 536 4189027 YP_669123.1 CDS ECP_1211 NC_008253.1 1243825 1244109 R hypothetical protein complement(1243825..1244109) Escherichia coli 536 4189028 YP_669124.1 CDS ECP_1212 NC_008253.1 1244171 1244344 R hypothetical protein complement(1244171..1244344) Escherichia coli 536 4189029 YP_669125.1 CDS ECP_1213 NC_008253.1 1244445 1244630 D hypothetical protein 1244445..1244630 Escherichia coli 536 4189030 YP_669126.1 CDS ECP_1214 NC_008253.1 1244762 1245088 D autotransporter 1244762..1245088 Escherichia coli 536 4189850 YP_669127.1 CDS ECP_1215 NC_008253.1 1245134 1245319 D hypothetical protein 1245134..1245319 Escherichia coli 536 4189851 YP_669128.1 CDS minE NC_008253.1 1245461 1245727 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1245461..1245727) Escherichia coli 536 4189852 YP_669129.1 CDS ECP_1217 NC_008253.1 1245731 1246543 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1245731..1246543) Escherichia coli 536 4189853 YP_669130.1 CDS minC NC_008253.1 1246567 1247262 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1246567..1247262) Escherichia coli 536 4189854 YP_669131.1 CDS ECP_1219 NC_008253.1 1247402 1247629 D hypothetical protein 1247402..1247629 Escherichia coli 536 4189855 YP_669132.1 CDS ECP_1220 NC_008253.1 1247782 1248150 D hypothetical protein 1247782..1248150 Escherichia coli 536 4189856 YP_669133.1 CDS ECP_1221 NC_008253.1 1248253 1248654 R protein YcgK complement(1248253..1248654) Escherichia coli 536 4189857 YP_669134.1 CDS ECP_1222 NC_008253.1 1248863 1249189 D hypothetical protein 1248863..1249189 Escherichia coli 536 4189858 YP_669135.1 CDS ECP_1223 NC_008253.1 1249261 1249920 D hypothetical protein 1249261..1249920 Escherichia coli 536 4189859 YP_669136.2 CDS ECP_1224 NC_008253.1 1250012 1250458 D hypothetical protein 1250012..1250458 Escherichia coli 536 4189860 YP_669137.1 CDS ECP_1225 NC_008253.1 1250665 1250946 R hypothetical protein complement(1250665..1250946) Escherichia coli 536 4189861 YP_669138.1 CDS ECP_1226 NC_008253.1 1251238 1251657 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1251238..1251657 Escherichia coli 536 4189862 YP_669139.1 CDS umuC NC_008253.1 1251657 1252925 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1251657..1252925 Escherichia coli 536 4189863 YP_669140.1 CDS ECP_1228 NC_008253.1 1252970 1253500 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1252970..1253500) Escherichia coli 536 4189864 YP_669141.1 CDS nhaB NC_008253.1 1253646 1255187 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1253646..1255187) Escherichia coli 536 4189865 YP_669142.1 CDS ECP_1230 NC_008253.1 1255409 1256128 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1255409..1256128 Escherichia coli 536 4189866 YP_669143.1 CDS ECP_1231 NC_008253.1 1256291 1257823 R SpoVR family protein complement(1256291..1257823) Escherichia coli 536 4189867 YP_669144.1 CDS ECP_1232 NC_008253.1 1258153 1259451 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1258153..1259451 Escherichia coli 536 4189868 YP_669145.1 CDS dadX NC_008253.1 1259461 1260531 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1259461..1260531 Escherichia coli 536 4189869 YP_669146.1 CDS ECP_1234 NC_008253.1 1260588 1262324 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1260588..1262324) Escherichia coli 536 4191976 YP_669147.1 CDS ldcA NC_008253.1 1262419 1263333 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1262419..1263333) Escherichia coli 536 4191977 YP_669148.1 CDS ECP_1236 NC_008253.1 1263319 1264044 D membrane-bound lytic murein transglycosylase E 1263319..1264044 Escherichia coli 536 4191978 YP_669149.1 CDS ECP_1237 NC_008253.1 1264046 1264780 R hypothetical protein complement(1264046..1264780) Escherichia coli 536 4191979 YP_669150.1 CDS ECP_1238 NC_008253.1 1264981 1265235 D transglycosylase associated protein 1264981..1265235 Escherichia coli 536 4191980 YP_669151.1 CDS ECP_1239 NC_008253.1 1265285 1267255 R TonB-dependent outer membrane receptor complement(1265285..1267255) Escherichia coli 536 4191981 YP_669152.1 CDS ECP_1240 NC_008253.1 1267281 1268135 R involved in molybdenum transport; molybdenum transport protein ModD complement(1267281..1268135) Escherichia coli 536 4191982 YP_669153.1 CDS ECP_1241 NC_008253.1 1268132 1268944 R hypothetical protein complement(1268132..1268944) Escherichia coli 536 4191983 YP_669154.1 CDS ECP_1242 NC_008253.1 1268954 1269712 R iron ABC transporter ATP-binding protein complement(1268954..1269712) Escherichia coli 536 4191984 YP_669155.1 CDS ECP_1243 NC_008253.1 1269709 1270689 R iron(III) ABC transporter permease complement(1269709..1270689) Escherichia coli 536 4191985 YP_669156.1 CDS ECP_1244 NC_008253.1 1270689 1271711 R iron ABC transporter substrate-binding protein complement(1270689..1271711) Escherichia coli 536 4191986 YP_669157.1 CDS treA NC_008253.1 1272048 1273745 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1272048..1273745) Escherichia coli 536 4191987 YP_669158.1 CDS ECP_1246 NC_008253.1 1274065 1275483 R phosphotransferaese subunit; phosphorylates dihydroxyacetone; dihydroxyacetone kinase subunit DhaM complement(1274065..1275483) Escherichia coli 536 4191988 YP_669159.1 CDS ECP_1247 NC_008253.1 1275494 1276126 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase ADP-binding subunit complement(1275494..1276126) Escherichia coli 536 4191989 YP_669160.1 CDS ECP_1248 NC_008253.1 1276137 1277207 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1276137..1277207) Escherichia coli 536 4191990 YP_669161.1 CDS ECP_1249 NC_008253.1 1277435 1279354 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1277435..1279354 Escherichia coli 536 4191991 YP_669162.1 CDS ECP_1250 NC_008253.1 1279391 1279621 R hypothetical protein complement(1279391..1279621) Escherichia coli 536 4191992 YP_669163.1 CDS ECP_1251 NC_008253.1 1279759 1280850 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1279759..1280850) Escherichia coli 536 4191993 YP_669164.1 CDS ECP_1252 NC_008253.1 1280967 1281551 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1280967..1281551) Escherichia coli 536 4191994 YP_669165.1 CDS ECP_1253 NC_008253.1 1281829 1282107 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1281829..1282107 Escherichia coli 536 4189735 YP_669166.1 CDS ECP_1254 NC_008253.1 1282162 1283814 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1282162..1283814) Escherichia coli 536 4189736 YP_669167.1 CDS ECP_1255 NC_008253.1 1283966 1284913 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1283966..1284913) Escherichia coli 536 4189737 YP_669168.1 CDS ipk NC_008253.1 1285064 1285915 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1285064..1285915) Escherichia coli 536 4189738 YP_669169.1 CDS lolB NC_008253.1 1285915 1286538 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB complement(1285915..1286538) Escherichia coli 536 4189739 YP_669170.1 CDS hemA NC_008253.1 1286752 1288008 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1286752..1288008 Escherichia coli 536 4189740 YP_669171.1 CDS prfA NC_008253.1 1288050 1289132 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1288050..1289132 Escherichia coli 536 4189741 YP_669172.1 CDS ECP_1260 NC_008253.1 1289132 1289965 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1289132..1289965 Escherichia coli 536 4189742 YP_669173.1 CDS ECP_1261 NC_008253.1 1289962 1290354 D transcriptional regulator 1289962..1290354 Escherichia coli 536 4189743 YP_669174.1 CDS ECP_1262 NC_008253.1 1290358 1291167 D transcriptional regulator 1290358..1291167 Escherichia coli 536 4189744 YP_669175.1 CDS ECP_1263 NC_008253.1 1291203 1292057 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1291203..1292057 Escherichia coli 536 4189745 YP_669176.1 CDS ECP_1264 NC_008253.1 1292205 1292372 R hypothetical protein complement(1292205..1292372) Escherichia coli 536 4189746 YP_669177.1 CDS ECP_1265 NC_008253.1 1292717 1293817 R calcium/sodium:proton antiporter complement(1292717..1293817) Escherichia coli 536 4189747 YP_669178.1 CDS chaB NC_008253.1 1294087 1294317 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1294087..1294317 Escherichia coli 536 4189748 YP_669179.1 CDS ECP_1267 NC_008253.1 1294454 1295170 D cation transport protein ChaC 1294454..1295170 Escherichia coli 536 4189749 YP_669180.1 CDS ECP_1268 NC_008253.1 1295214 1295567 R hypothetical protein complement(1295214..1295567) Escherichia coli 536 4189750 YP_669181.1 CDS ECP_1269 NC_008253.1 1295752 1297146 D hypothetical protein 1295752..1297146 Escherichia coli 536 4189751 YP_669182.1 CDS ECP_1270 NC_008253.1 1297147 1297797 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1297147..1297797) Escherichia coli 536 4189752 YP_669183.1 CDS ECP_1271 NC_008253.1 1297790 1299586 R nitrate/nitrite sensor protein NarX complement(1297790..1299586) Escherichia coli 536 4189753 YP_669184.1 CDS ECP_1272 NC_008253.1 1299612 1299830 D hypothetical protein 1299612..1299830 Escherichia coli 536 4189754 YP_669185.1 CDS ECP_1273 NC_008253.1 1299925 1301316 D nitrite extrusion protein 1299925..1301316 Escherichia coli 536 4189755 YP_669186.1 CDS ECP_1274 NC_008253.1 1301709 1305452 D respiratory nitrate reductase 1 subunit alpha 1301709..1305452 Escherichia coli 536 4189756 YP_669187.1 CDS ECP_1275 NC_008253.1 1305449 1306987 D respiratory nitrate reductase 1 subunit beta 1305449..1306987 Escherichia coli 536 4189757 YP_669188.1 CDS ECP_1276 NC_008253.1 1306984 1307694 D respiratory nitrate reductase 1 subunit delta 1306984..1307694 Escherichia coli 536 4189758 YP_669189.1 CDS ECP_1277 NC_008253.1 1307694 1308371 D respiratory nitrate reductase 1 subunit gamma 1307694..1308371 Escherichia coli 536 4189759 YP_669190.1 CDS ECP_1278 NC_008253.1 1308424 1309623 R transposase complement(1308424..1309623) Escherichia coli 536 4189760 YP_669191.1 CDS purU NC_008253.1 1310417 1311259 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1310417..1311259) Escherichia coli 536 4189761 YP_669192.1 CDS ECP_1280 NC_008253.1 1311309 1311767 R hypothetical protein complement(1311309..1311767) Escherichia coli 536 4189762 YP_669193.1 CDS ECP_1281 NC_008253.1 1311880 1312785 D hypothetical protein 1311880..1312785 Escherichia coli 536 4189763 YP_669194.1 CDS ECP_1282 NC_008253.1 1312877 1313890 D response regulator of RpoS 1312877..1313890 Escherichia coli 536 4189764 YP_669195.1 CDS ECP_1283 NC_008253.1 1314092 1315000 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1314092..1315000 Escherichia coli 536 4189765 YP_669196.1 CDS ECP_1284 NC_008253.1 1315144 1315557 R global DNA-binding transcriptional dual regulator H-NS complement(1315144..1315557) Escherichia coli 536 4189766 YP_669197.1 CDS ECP_1285 NC_008253.1 1316161 1316778 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1316161..1316778 Escherichia coli 536 4189767 YP_669198.1 CDS ECP_1286 NC_008253.1 1316905 1318110 R for insertion sequence element IS4; transposase InsG complement(1316905..1318110) Escherichia coli 536 4189768 YP_669199.1 CDS ECP_1287 NC_008253.1 1318236 1320911 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1318236..1320911) Escherichia coli 536 4189769 YP_669200.1 CDS ECP_1288 NC_008253.1 1321388 1322035 D hypothetical protein 1321388..1322035 Escherichia coli 536 4189770 YP_669201.1 CDS ECP_1289 NC_008253.1 1322193 1322489 R hypothetical protein complement(1322193..1322489) Escherichia coli 536 4189771 YP_669202.1 CDS ECP_1290 NC_008253.1 1322728 1324404 D periplasmic oligopeptide-binding protein 1322728..1324404 Escherichia coli 536 4189772 YP_669203.1 CDS oppB NC_008253.1 1324490 1325410 D oligopeptide transporter permease 1324490..1325410 Escherichia coli 536 4189773 YP_669204.1 CDS ECP_1292 NC_008253.1 1325425 1326333 D oligopeptide transport system permease OppC 1325425..1326333 Escherichia coli 536 4190235 YP_669205.1 CDS oppD NC_008253.1 1326345 1327358 D oligopeptide ABC transporter ATP-binding protein 1326345..1327358 Escherichia coli 536 4190236 YP_669206.1 CDS ECP_1294 NC_008253.1 1327355 1328359 D oligopeptide transport ATP-binding protein OppF 1327355..1328359 Escherichia coli 536 4190237 YP_669207.1 CDS ECP_1295 NC_008253.1 1328411 1328740 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1328411..1328740) Escherichia coli 536 4190238 YP_669208.1 CDS cls NC_008253.1 1328775 1330235 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1328775..1330235) Escherichia coli 536 4190239 YP_669209.1 CDS ECP_1297 NC_008253.1 1330345 1330551 D hypothetical protein 1330345..1330551 Escherichia coli 536 4190240 YP_669210.1 CDS ECP_1298 NC_008253.1 1330606 1331859 R voltage-gated potassium channel complement(1330606..1331859) Escherichia coli 536 4190241 YP_669211.1 CDS ECP_1299 NC_008253.1 1332159 1332455 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein complement(1332159..1332455) Escherichia coli 536 4190242 YP_669212.1 CDS ECP_1300 NC_008253.1 1332664 1333395 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1332664..1333395 Escherichia coli 536 4190243 YP_669213.1 CDS ECP_1301 NC_008253.1 1333435 1333833 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase complement(1333435..1333833) Escherichia coli 536 4190244 YP_669214.1 CDS ECP_1302 NC_008253.1 1333939 1334478 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1333939..1334478) Escherichia coli 536 4190245 YP_669215.1 CDS ECP_1303 NC_008253.1 1334508 1335251 R hypothetical protein complement(1334508..1335251) Escherichia coli 536 4190246 YP_669216.1 CDS ECP_1304 NC_008253.1 1335558 1336244 D receptor for colicin S4; outer membrane protein W 1335558..1336244 Escherichia coli 536 4190247 YP_669217.1 CDS ECP_1305 NC_008253.1 1336303 1336809 R protein YciE complement(1336303..1336809) Escherichia coli 536 4190248 YP_669218.1 CDS ECP_1306 NC_008253.1 1336855 1337355 R protein YciF complement(1336855..1337355) Escherichia coli 536 4190249 YP_669219.1 CDS ECP_1307 NC_008253.1 1337441 1337620 R hypothetical protein complement(1337441..1337620) Escherichia coli 536 4190250 YP_669220.1 CDS trpA NC_008253.1 1338001 1338807 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1338001..1338807) Escherichia coli 536 4190251 YP_669221.1 CDS ECP_1309 NC_008253.1 1338807 1340000 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1338807..1340000) Escherichia coli 536 4190252 YP_669222.1 CDS ECP_1310 NC_008253.1 1340012 1341370 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1340012..1341370) Escherichia coli 536 4190253 YP_669223.1 CDS ECP_1311 NC_008253.1 1341374 1342969 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1341374..1342969) Escherichia coli 536 4190254 YP_669224.1 CDS ECP_1312 NC_008253.1 1342969 1344531 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1342969..1344531) Escherichia coli 536 4189870 YP_669225.1 CDS ECP_1313 NC_008253.1 1344805 1345686 D phosphotransferase domain-containing protein 1344805..1345686 Escherichia coli 536 4189871 YP_669226.1 CDS ECP_1314 NC_008253.1 1345683 1346303 D hypothetical protein 1345683..1346303 Escherichia coli 536 4189872 YP_669227.1 CDS ECP_1315 NC_008253.1 1346328 1348220 D membrane protein YciQ 1346328..1348220 Escherichia coli 536 4189873 YP_669228.1 CDS ECP_1316 NC_008253.1 1348433 1349308 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1348433..1349308 Escherichia coli 536 4189874 YP_669229.1 CDS ECP_1317 NC_008253.1 1349478 1350500 D hypothetical protein 1349478..1350500 Escherichia coli 536 4189875 YP_669230.1 CDS ECP_1318 NC_008253.1 1350510 1350818 D hypothetical protein 1350510..1350818 Escherichia coli 536 4189876 YP_669231.1 CDS ECP_1319 NC_008253.1 1350875 1351465 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1350875..1351465) Escherichia coli 536 4189877 YP_669232.1 CDS ECP_1320 NC_008253.1 1351462 1352220 R short chain dehydrogenase complement(1351462..1352220) Escherichia coli 536 4189878 YP_669233.1 CDS ECP_1321 NC_008253.1 1352264 1352428 R hypothetical protein complement(1352264..1352428) Escherichia coli 536 4189879 YP_669234.1 CDS ECP_1322 NC_008253.1 1352440 1353489 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1352440..1353489 Escherichia coli 536 4189880 YP_669235.1 CDS ECP_1323 NC_008253.1 1353525 1353776 R hypothetical protein complement(1353525..1353776) Escherichia coli 536 4189881 YP_669236.1 CDS ECP_1324 NC_008253.1 1353821 1354033 D hypothetical protein 1353821..1354033 Escherichia coli 536 4189882 YP_669237.1 CDS ECP_1325 NC_008253.1 1354114 1356753 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1354114..1356753 Escherichia coli 536 4189883 YP_669238.1 CDS cysB NC_008253.1 1356963 1357937 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1356963..1357937 Escherichia coli 536 4189884 YP_669239.1 CDS ECP_1327 NC_008253.1 1358268 1358396 D hypothetical protein 1358268..1358396 Escherichia coli 536 4189885 YP_669240.1 CDS ECP_1328 NC_008253.1 1358399 1358566 D hypothetical protein 1358399..1358566 Escherichia coli 536 4189886 YP_669241.1 CDS ECP_1329 NC_008253.1 1358925 1361600 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1358925..1361600 Escherichia coli 536 4189887 YP_669242.1 CDS ribA NC_008253.1 1361664 1362254 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1361664..1362254) Escherichia coli 536 4189888 YP_669243.1 CDS ECP_1331 NC_008253.1 1362424 1363188 D phosphatidylglycerophosphatase B 1362424..1363188 Escherichia coli 536 4190314 YP_669244.1 CDS ECP_1332 NC_008253.1 1363337 1363645 D hypothetical protein 1363337..1363645 Escherichia coli 536 4190315 YP_669245.1 CDS ECP_1333 NC_008253.1 1363652 1364821 D tetratricopeptide repeat protein 1363652..1364821 Escherichia coli 536 4190316 YP_669246.1 CDS ECP_1334 NC_008253.1 1365013 1365750 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1365013..1365750 Escherichia coli 536 4190317 YP_669247.1 CDS ECP_1335 NC_008253.1 1365750 1366076 D hypothetical translation initiation factor SUI; involved in start site selection during the initiation of translation; translation initiation factor Sui1 1365750..1366076 Escherichia coli 536 4190318 YP_669248.1 CDS ECP_1336 NC_008253.1 1366202 1366420 R lipoprotein complement(1366202..1366420) Escherichia coli 536 4190319 YP_669249.1 CDS ECP_1337 NC_008253.1 1366689 1367438 R regulatory protein YciT complement(1366689..1367438) Escherichia coli 536 4190320 YP_669250.1 CDS ECP_1338 NC_008253.1 1367528 1367701 R hypothetical protein complement(1367528..1367701) Escherichia coli 536 4190321 YP_669251.1 CDS ECP_1339 NC_008253.1 1367849 1369834 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1367849..1369834) Escherichia coli 536 4190322 YP_669252.1 CDS ECP_1340 NC_008253.1 1370068 1372002 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1370068..1372002) Escherichia coli 536 4190323 YP_669253.1 CDS ECP_1341 NC_008253.1 1372070 1373197 R hypothetical protein complement(1372070..1373197) Escherichia coli 536 4190324 YP_669254.1 CDS ECP_1342 NC_008253.1 1373342 1374130 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1373342..1374130) Escherichia coli 536 4190325 YP_669255.1 CDS ECP_1343 NC_008253.1 1374608 1375174 D TetR family transcriptional regulator 1374608..1375174 Escherichia coli 536 4190326 YP_669256.1 CDS ECP_1344 NC_008253.1 1375323 1376444 D multidrug-efflux transport protein 1375323..1376444 Escherichia coli 536 4190327 YP_669257.1 CDS ECP_1345 NC_008253.1 1376444 1379551 D multidrug efflux protein 1376444..1379551 Escherichia coli 536 4190328 YP_669258.1 CDS ECP_1346 NC_008253.1 1379555 1380928 D outer membrane efflux lipoprotein 1379555..1380928 Escherichia coli 536 4190329 YP_669259.1 CDS ECP_1347 NC_008253.1 1380937 1382100 D drug transport transmembrane protein 1380937..1382100 Escherichia coli 536 4190330 YP_669260.1 CDS ECP_1348 NC_008253.1 1382148 1382954 R peptide transport system ATP-binding protein SapF complement(1382148..1382954) Escherichia coli 536 4190331 YP_669261.1 CDS ECP_1349 NC_008253.1 1382956 1383948 R peptide transport system ATP-binding protein SapD complement(1382956..1383948) Escherichia coli 536 4190332 YP_669262.1 CDS ECP_1350 NC_008253.1 1383948 1384838 R peptide transport system permease SapC complement(1383948..1384838) Escherichia coli 536 4190333 YP_669263.1 CDS ECP_1351 NC_008253.1 1384825 1385790 R peptide transport system permease SapB complement(1384825..1385790) Escherichia coli 536 4191878 YP_669264.1 CDS ECP_1352 NC_008253.1 1385787 1387430 R peptide transport periplasmic protein SapA complement(1385787..1387430) Escherichia coli 536 4191879 YP_669265.1 CDS ECP_1353 NC_008253.1 1387743 1387988 R hypothetical protein complement(1387743..1387988) Escherichia coli 536 4191880 YP_669266.1 CDS ECP_1354 NC_008253.1 1388102 1388284 D hypothetical protein 1388102..1388284 Escherichia coli 536 4191881 YP_669267.1 CDS pspF NC_008253.1 1388415 1389392 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1388415..1389392) Escherichia coli 536 4191882 YP_669268.1 CDS ECP_1356 NC_008253.1 1389558 1390226 D negative regulatory gene for the psp opreon; involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1389558..1390226 Escherichia coli 536 4191883 YP_669269.1 CDS pspB NC_008253.1 1390280 1390504 D phage shock regulatory protein; acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1390280..1390504 Escherichia coli 536 4191884 YP_669270.1 CDS ECP_1358 NC_008253.1 1390504 1390863 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1390504..1390863 Escherichia coli 536 4191885 YP_669271.1 CDS ECP_1359 NC_008253.1 1390872 1391093 D peripheral inner membrane phage-shock protein 1390872..1391093 Escherichia coli 536 4191886 YP_669272.1 CDS ECP_1360 NC_008253.1 1391168 1391482 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1391168..1391482 Escherichia coli 536 4191887 YP_669273.1 CDS ECP_1361 NC_008253.1 1391665 1393371 D sucrose phosphorylase 1391665..1393371 Escherichia coli 536 4191888 YP_669274.1 CDS ECP_1362 NC_008253.1 1393385 1394677 D ABC transporter substrate-binding protein 1393385..1394677 Escherichia coli 536 4191889 YP_669275.1 CDS ECP_1363 NC_008253.1 1394698 1395579 D YcjO protein; binding-protein-dependent transport system inner membrane protein 1394698..1395579 Escherichia coli 536 4191890 YP_669276.1 CDS ECP_1364 NC_008253.1 1395566 1396408 D YcjP protein; binding-protein-dependent transport system inner membrane protein 1395566..1396408 Escherichia coli 536 4191891 YP_669277.1 CDS ECP_1365 NC_008253.1 1396439 1397491 D zinc-type alcohol dehydrogenase-like protein YcjQ 1396439..1397491 Escherichia coli 536 4191892 YP_669278.1 CDS ECP_1366 NC_008253.1 1397510 1398298 D hypothetical protein 1397510..1398298 Escherichia coli 536 4191893 YP_669279.1 CDS ECP_1367 NC_008253.1 1398320 1399363 D oxidoreductase YcjS 1398320..1399363 Escherichia coli 536 4191894 YP_669280.1 CDS ECP_1368 NC_008253.1 1399360 1401627 D glycosyl hydrolase 1399360..1401627 Escherichia coli 536 4191895 YP_669281.1 CDS ECP_1369 NC_008253.1 1401624 1402283 D beta-phosphoglucomutase 1401624..1402283 Escherichia coli 536 4191896 YP_669282.1 CDS ECP_1370 NC_008253.1 1402297 1402632 D similar to N-terminal part of ATP-binding protein YcjV; ABC transporter 1402297..1402632 Escherichia coli 536 4188149 YP_669283.1 CDS ECP_1371 NC_008253.1 1402640 1403380 D similar to C-terminal part of ATP-binding protein YcjV; ABC transporter 1402640..1403380 Escherichia coli 536 4188150 YP_669284.1 CDS ECP_1372 NC_008253.1 1403425 1404330 D outer membrane protein G 1403425..1404330 Escherichia coli 536 4188151 YP_669285.1 CDS ECP_1373 NC_008253.1 1404381 1405379 R transcriptional regulator YcjW complement(1404381..1405379) Escherichia coli 536 4188152 YP_669286.1 CDS ECP_1374 NC_008253.1 1405534 1406931 D hypothetical protein 1405534..1406931 Escherichia coli 536 4188153 YP_669287.1 CDS ECP_1375 NC_008253.1 1406928 1407989 D hypothetical protein 1406928..1407989 Escherichia coli 536 4188154 YP_669288.1 CDS ECP_1376 NC_008253.1 1408137 1409678 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1408137..1409678 Escherichia coli 536 4188155 YP_669289.1 CDS tpx NC_008253.1 1409722 1410228 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1409722..1410228) Escherichia coli 536 4188156 YP_669290.1 CDS ECP_1378 NC_008253.1 1410347 1411312 D hypothetical protein YcjG; mandelate racemase/muconate lactonizing enzyme family protein 1410347..1411312 Escherichia coli 536 4188157 YP_669291.1 CDS ECP_1379 NC_008253.1 1411287 1412015 R murein peptide amidase A complement(1411287..1412015) Escherichia coli 536 4188158 YP_669292.1 CDS ECP_1380 NC_008253.1 1412306 1412944 R hypothetical protein complement(1412306..1412944) Escherichia coli 536 4188159 YP_669293.1 CDS ECP_1381 NC_008253.1 1413015 1413935 R hypothetical protein complement(1413015..1413935) Escherichia coli 536 4188160 YP_669294.1 CDS ECP_1382 NC_008253.1 1414073 1414972 D LysR family transcriptional regulator 1414073..1414972 Escherichia coli 536 4188161 YP_669295.1 CDS ECP_1385 NC_008253.1 1416974 1418005 R hypothetical protein complement(1416974..1418005) Escherichia coli 536 4188164 YP_669296.1 CDS ECP_1386 NC_008253.1 1418249 1418506 D hypothetical protein 1418249..1418506 Escherichia coli 536 4188165 YP_669297.1 CDS ECP_1387 NC_008253.1 1418556 1419506 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1418556..1419506) Escherichia coli 536 4187564 YP_669298.1 CDS ECP_1388 NC_008253.1 1419658 1420452 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1419658..1420452) Escherichia coli 536 4187565 YP_669299.1 CDS ECP_1389 NC_008253.1 1420605 1421120 R O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1420605..1421120) Escherichia coli 536 4187566 YP_669300.1 CDS ECP_1390 NC_008253.1 1421633 1422448 R AraC family transcriptional regulator complement(1421633..1422448) Escherichia coli 536 4187567 YP_669301.1 CDS ECP_1391 NC_008253.1 1422545 1423573 D multidrug resistance protein A 1422545..1423573 Escherichia coli 536 4187568 YP_669302.1 CDS ECP_1392 NC_008253.1 1423570 1425084 D multidrug resistance protein B 1423570..1425084 Escherichia coli 536 4187569 YP_669303.1 CDS ECP_1393 NC_008253.1 1425279 1425842 D hypothetical protein 1425279..1425842 Escherichia coli 536 4187570 YP_669304.1 CDS ECP_1394 NC_008253.1 1425863 1427095 R hypothetical protein complement(1425863..1427095) Escherichia coli 536 4187571 YP_669305.1 CDS zntB NC_008253.1 1427350 1428333 D zinc transporter 1427350..1428333 Escherichia coli 536 4187572 YP_669306.1 CDS ECP_1396 NC_008253.1 1428608 1428781 D hypothetical protein 1428608..1428781 Escherichia coli 536 4187573 YP_669307.1 CDS ECP_1397 NC_008253.1 1428811 1430184 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1428811..1430184 Escherichia coli 536 4187574 YP_669308.1 CDS ECP_1398 NC_008253.1 1430313 1431248 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1430313..1431248) Escherichia coli 536 4187575 YP_669309.1 CDS ECP_1399 NC_008253.1 1431300 1431608 R hypothetical protein complement(1431300..1431608) Escherichia coli 536 4187576 YP_669310.1 CDS ECP_1400 NC_008253.1 1433117 1433485 R hypothetical protein complement(1433117..1433485) Escherichia coli 536 4187577 YP_669311.1 CDS ECP_1401 NC_008253.1 1433574 1434008 R universal stress protein complement(1433574..1434008) Escherichia coli 536 4187578 YP_669312.1 CDS ECP_1402 NC_008253.1 1434149 1435282 R outer membrane protein N complement(1434149..1435282) Escherichia coli 536 4187579 YP_669313.1 CDS ECP_1403 NC_008253.1 1435648 1439172 R pyruvate-flavodoxin oxidoreductase complement(1435648..1439172) Escherichia coli 536 4187580 YP_669314.1 CDS ECP_1404 NC_008253.1 1439446 1439712 D hypothetical protein 1439446..1439712 Escherichia coli 536 4187581 YP_669315.1 CDS ECP_1405 NC_008253.1 1439709 1440131 R heat-inducible protein complement(1439709..1440131) Escherichia coli 536 4187582 YP_669316.1 CDS ECP_1406 NC_008253.1 1440242 1441231 R D-lactate dehydrogenase complement(1440242..1441231) Escherichia coli 536 4187583 YP_669317.1 CDS ECP_1407 NC_008253.1 1441439 1444078 D hypothetical protein 1441439..1444078 Escherichia coli 536 4190894 YP_669318.1 CDS ECP_1408 NC_008253.1 1444075 1444260 D hypothetical protein 1444075..1444260 Escherichia coli 536 4190895 YP_669319.1 CDS ECP_1409 NC_008253.1 1444220 1444594 D hypothetical protein 1444220..1444594 Escherichia coli 536 4190896 YP_669320.1 CDS ECP_1410 NC_008253.1 1444970 1452346 D autotransporter/adhesin 1444970..1452346 Escherichia coli 536 4190897 YP_669321.1 CDS ECP_1411 NC_008253.1 1452555 1453415 D oxidoreductase 1452555..1453415 Escherichia coli 536 4190898 YP_669322.1 CDS ECP_1412 NC_008253.1 1453460 1453684 R hypothetical protein complement(1453460..1453684) Escherichia coli 536 4190899 YP_669323.1 CDS ECP_1413 NC_008253.1 1453714 1454319 D CDP-alcohol phosphatidyltransferase 1453714..1454319 Escherichia coli 536 4190900 YP_669324.1 CDS ECP_1414 NC_008253.1 1454493 1455215 D phosphatidate cytidylyltransferase 1454493..1455215 Escherichia coli 536 4190901 YP_669325.1 CDS ECP_1415 NC_008253.1 1455231 1456988 D hypothetical protein 1455231..1456988 Escherichia coli 536 4190902 YP_669326.1 CDS ECP_1416 NC_008253.1 1457334 1458293 D dual specificity phosphatase 1457334..1458293 Escherichia coli 536 4190903 YP_669327.1 CDS ECP_1417 NC_008253.1 1458347 1458952 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1458347..1458952) Escherichia coli 536 4190904 YP_669328.1 CDS ECP_1418 NC_008253.1 1459153 1463055 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1459153..1463055 Escherichia coli 536 4190905 YP_669329.1 CDS ECP_1419 NC_008253.1 1463328 1464128 D hypothetical protein 1463328..1464128 Escherichia coli 536 4190906 YP_669330.1 CDS ECP_1420 NC_008253.1 1464325 1465764 D NAD-linked; aldehyde dehydrogenase 1464325..1465764 Escherichia coli 536 4190907 YP_669331.1 CDS ECP_1421 NC_008253.1 1465806 1466807 R glyceraldehyde 3-phosphate dehydrogenase C complement(1465806..1466807) Escherichia coli 536 4190908 YP_669332.1 CDS ECP_1422 NC_008253.1 1466996 1467526 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1466996..1467526 Escherichia coli 536 4190909 YP_669333.1 CDS ECP_1423 NC_008253.1 1467771 1467944 D hypothetical protein 1467771..1467944 Escherichia coli 536 4190910 YP_669335.1 CDS ECP_1427 NC_008253.1 1470232 1471155 R LysR family transcriptional regulator complement(1470232..1471155) Escherichia coli 536 4188280 YP_669336.1 CDS ECP_1428 NC_008253.1 1471372 1472715 D hypothetical protein 1471372..1472715 Escherichia coli 536 4188281 YP_669337.1 CDS mdoD NC_008253.1 1472976 1474595 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1472976..1474595 Escherichia coli 536 4188282 YP_669338.1 CDS ECP_1430 NC_008253.1 1474735 1474959 D hypothetical protein 1474735..1474959 Escherichia coli 536 4188283 YP_669339.1 CDS ECP_1431 NC_008253.1 1475022 1475561 D ribosomal-protein-L7/L12-serine acetyltransferase 1475022..1475561 Escherichia coli 536 4188284 YP_669340.1 CDS ECP_1432 NC_008253.1 1475553 1476533 R hypothetical protein complement(1475553..1476533) Escherichia coli 536 4188285 YP_669341.1 CDS ECP_1433 NC_008253.1 1476645 1477649 D potassium-tellurite ethidium and proflavin transporter 1476645..1477649 Escherichia coli 536 4188286 YP_669342.1 CDS ECP_1434 NC_008253.1 1477646 1478239 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1477646..1478239 Escherichia coli 536 4188287 YP_669343.1 CDS ECP_1435 NC_008253.1 1478542 1479210 D lipoprotein YdcL 1478542..1479210 Escherichia coli 536 4188288 YP_669344.1 CDS ECP_1436 NC_008253.1 1479245 1480510 R benzoate membrane transport protein complement(1479245..1480510) Escherichia coli 536 4188289 YP_669345.1 CDS ECP_1437 NC_008253.1 1480509 1481045 D hypothetical protein 1480509..1481045 Escherichia coli 536 4188290 YP_669346.1 CDS ECP_1438 NC_008253.1 1481076 1483079 D peptidase 1481076..1483079 Escherichia coli 536 4188291 YP_669347.1 CDS ECP_1439 NC_008253.1 1483171 1483401 R hypothetical protein complement(1483171..1483401) Escherichia coli 536 4188292 YP_669348.1 CDS ECP_1440 NC_008253.1 1483613 1483816 D hypothetical protein 1483613..1483816 Escherichia coli 536 4188293 YP_669349.1 CDS ECP_1441 NC_008253.1 1483895 1485301 D GntR family transcriptional regulator 1483895..1485301 Escherichia coli 536 4188294 YP_669350.1 CDS ECP_1442 NC_008253.1 1485546 1486691 D extracellular solute-binding protein YdcS 1485546..1486691 Escherichia coli 536 4188295 YP_669351.1 CDS ECP_1443 NC_008253.1 1486709 1487722 D ABC transporter ATP-binding protein 1486709..1487722 Escherichia coli 536 4187342 YP_669352.1 CDS ECP_1444 NC_008253.1 1487723 1488664 D binding-protein-dependent transport system inner membrane protein 1487723..1488664 Escherichia coli 536 4187343 YP_669353.1 CDS ECP_1445 NC_008253.1 1488654 1489448 D hypothetical protein 1488654..1489448 Escherichia coli 536 4187344 YP_669354.1 CDS ECP_1446 NC_008253.1 1489470 1490894 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1489470..1490894 Escherichia coli 536 4187345 YP_669355.1 CDS ECP_1447 NC_008253.1 1491233 1491454 D inner membrane protein 1491233..1491454 Escherichia coli 536 4187346 YP_669356.1 CDS ECP_1448 NC_008253.1 1491540 1491773 D hypothetical protein 1491540..1491773 Escherichia coli 536 4187347 YP_669357.1 CDS ECP_1449 NC_008253.1 1491774 1492223 R hypothetical protein complement(1491774..1492223) Escherichia coli 536 4187348 YP_669358.1 CDS ECP_1450 NC_008253.1 1492220 1492738 R acetyltransferase YncA complement(1492220..1492738) Escherichia coli 536 4187349 YP_669359.1 CDS ECP_1451 NC_008253.1 1492945 1493181 D hypothetical protein 1492945..1493181 Escherichia coli 536 4187350 YP_669360.1 CDS ECP_1452 NC_008253.1 1493219 1495321 R tonB-dependent receptor YncD complement(1493219..1495321) Escherichia coli 536 4187351 YP_669361.1 CDS ECP_1453 NC_008253.1 1495563 1496624 D hypothetical protein 1495563..1496624 Escherichia coli 536 4187352 YP_669362.1 CDS ECP_1454 NC_008253.1 1496737 1498236 R L-asparagine permease complement(1496737..1498236) Escherichia coli 536 4187353 YP_669363.1 CDS ECP_1455 NC_008253.1 1498503 1498679 D glutathione S-transferase 1498503..1498679 Escherichia coli 536 4187354 YP_669364.1 CDS ECP_1456 NC_008253.1 1498693 1499103 D glutathione S-transferase 1498693..1499103 Escherichia coli 536 4187355 YP_669365.1 CDS ECP_1457 NC_008253.1 1499644 1499928 D hypothetical protein 1499644..1499928 Escherichia coli 536 4187356 YP_669366.1 CDS ECP_1458 NC_008253.1 1499947 1502352 D Rhs/Vgr-family protein 1499947..1502352 Escherichia coli 536 4187357 YP_669367.1 CDS ECP_1459 NC_008253.1 1502342 1503103 D hypothetical protein 1502342..1503103 Escherichia coli 536 4187358 YP_669368.1 CDS ECP_1460 NC_008253.1 1503239 1503418 D hypothetical protein 1503239..1503418 Escherichia coli 536 4187359 YP_669369.1 CDS ECP_1461 NC_008253.1 1503472 1503939 D hypothetical protein 1503472..1503939 Escherichia coli 536 4187360 YP_669370.1 CDS ECP_1462 NC_008253.1 1504052 1504195 D H repeat-containing Rhs element protein 1504052..1504195 Escherichia coli 536 4187361 YP_669371.1 CDS ECP_1463 NC_008253.1 1504273 1504488 D hypothetical protein 1504273..1504488 Escherichia coli 536 4190996 YP_669372.1 CDS ECP_1464 NC_008253.1 1504805 1505374 R hypothetical protein complement(1504805..1505374) Escherichia coli 536 4190997 YP_669373.1 CDS ECP_1465 NC_008253.1 1505549 1506394 D N-hydroxyarylamine O-acetyltransferase 1505549..1506394 Escherichia coli 536 4190998 YP_669374.1 CDS ECP_1466 NC_008253.1 1506490 1507383 R hypothetical protein complement(1506490..1507383) Escherichia coli 536 4190999 YP_669375.1 CDS ECP_1467 NC_008253.1 1507463 1508143 R nitrate reductase 2 subunit gamma complement(1507463..1508143) Escherichia coli 536 4191000 YP_669376.1 CDS ECP_1468 NC_008253.1 1508140 1508835 R respiratory nitrate reductase 2 subunit delta complement(1508140..1508835) Escherichia coli 536 4191001 YP_669377.1 CDS ECP_1469 NC_008253.1 1508835 1510379 R respiratory nitrate reductase 2 subunit beta complement(1508835..1510379) Escherichia coli 536 4191002 YP_669378.1 CDS ECP_1470 NC_008253.1 1510376 1514116 R respiratory nitrate reductase 2 subunit a complement(1510376..1514116) Escherichia coli 536 4191003 YP_669379.1 CDS ECP_1471 NC_008253.1 1514211 1515599 R nitrite extrusion protein 2 complement(1514211..1515599) Escherichia coli 536 4191004 YP_669380.1 CDS ECP_1472 NC_008253.1 1515872 1516753 R hypothetical protein complement(1515872..1516753) Escherichia coli 536 4191005 YP_669382.1 CDS ECP_1474 NC_008253.1 1516986 1517573 D formate dehydrogenase, nitrate-inducible, major subunit 1516986..1517573 Escherichia coli 536 4191007 YP_669383.1 CDS ECP_1475 NC_008253.1 1517622 1520033 D formate dehydrogenase, nitrate-inducible, major subunit 1517622..1520033 Escherichia coli 536 4191008 YP_669384.1 CDS ECP_1476 NC_008253.1 1520052 1520930 D formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 1520052..1520930 Escherichia coli 536 4191009 YP_669385.1 CDS ECP_1477 NC_008253.1 1520905 1521576 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1520905..1521576 Escherichia coli 536 4191010 YP_669386.1 CDS ECP_1478 NC_008253.1 1521805 1522089 R HTH-type transcriptional regulator YddM complement(1521805..1522089) Escherichia coli 536 4191011 YP_669387.1 CDS ECP_1479 NC_008253.1 1522089 1522361 R hypothetical protein complement(1522089..1522361) Escherichia coli 536 4191012 YP_669388.1 CDS ECP_1480 NC_008253.1 1522553 1523563 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1522553..1523563) Escherichia coli 536 4191013 YP_669389.1 CDS ECP_1481 NC_008253.1 1523697 1525394 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1523697..1525394) Escherichia coli 536 4191014 YP_669390.1 CDS rpsV NC_008253.1 1525551 1525688 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1525551..1525688) Escherichia coli 536 4191858 YP_669391.1 CDS ECP_1483 NC_008253.1 1525790 1526005 R biofilm-dependent modulation protein complement(1525790..1526005) Escherichia coli 536 4191859 YP_669392.1 CDS ECP_1484 NC_008253.1 1526350 1526781 D osmotically inducible protein C 1526350..1526781 Escherichia coli 536 4191860 YP_669393.1 CDS ECP_1485 NC_008253.1 1526971 1529370 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1526971..1529370) Escherichia coli 536 4191861 YP_669394.1 CDS ECP_1486 NC_008253.1 1529395 1529607 R hypothetical protein complement(1529395..1529607) Escherichia coli 536 4191862 YP_669395.1 CDS ECP_1487 NC_008253.1 1529937 1531256 R lipoprotein YddW precursor complement(1529937..1531256) Escherichia coli 536 4191863 YP_669396.1 CDS ECP_1488 NC_008253.1 1531387 1532922 R amino acid antiporter complement(1531387..1532922) Escherichia coli 536 4191864 YP_669397.1 CDS ECP_1489 NC_008253.1 1533078 1534478 R glutamate decarboxylase complement(1533078..1534478) Escherichia coli 536 4191865 YP_669398.1 CDS ECP_1490 NC_008253.1 1534840 1537623 R zinc protease PqqL complement(1534840..1537623) Escherichia coli 536 4191866 YP_669399.1 CDS ECP_1491 NC_008253.1 1537680 1540052 R hypothetical protein complement(1537680..1540052) Escherichia coli 536 4191867 YP_669400.1 CDS ECP_1492 NC_008253.1 1540090 1541775 R ABC transporter ATP-binding protein complement(1540090..1541775) Escherichia coli 536 4191868 YP_669401.1 CDS ECP_1493 NC_008253.1 1542066 1543223 R hypothetical protein complement(1542066..1543223) Escherichia coli 536 4191869 YP_669402.1 CDS ECP_1494 NC_008253.1 1543275 1544957 R sulfatase YdeN complement(1543275..1544957) Escherichia coli 536 4191870 YP_669403.1 CDS ECP_1495 NC_008253.1 1545359 1546120 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1545359..1546120) Escherichia coli 536 4191871 YP_669404.1 CDS ECP_1496 NC_008253.1 1546196 1546393 R hypothetical protein complement(1546196..1546393) Escherichia coli 536 4191872 YP_669405.1 CDS ECP_1497 NC_008253.1 1546641 1548920 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase complement(1546641..1548920) Escherichia coli 536 4191873 YP_669406.1 CDS ECP_1498 NC_008253.1 1549206 1549493 R fimbrial-like protein complement(1549206..1549493) Escherichia coli 536 4191874 YP_669407.1 CDS ECP_1499 NC_008253.1 1549507 1550343 R fimbrial usher protein complement(1549507..1550343) Escherichia coli 536 4191875 YP_669408.1 CDS ECP_1500 NC_008253.1 1550384 1551055 D transcriptional regulator 1550384..1551055 Escherichia coli 536 4191876 YP_669409.1 CDS ECP_1501 NC_008253.1 1551349 1552221 R hypothetical protein complement(1551349..1552221) Escherichia coli 536 4191877 YP_669410.1 CDS ECP_1502 NC_008253.1 1552221 1552505 R DNA-binding transcriptional regulator HipB complement(1552221..1552505) Escherichia coli 536 4187927 YP_669411.1 CDS ECP_1503 NC_008253.1 1552795 1553553 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1552795..1553553 Escherichia coli 536 4187928 YP_669412.1 CDS ECP_1504 NC_008253.1 1553557 1554471 R hypothetical protein complement(1553557..1554471) Escherichia coli 536 4187929 YP_669413.1 CDS ECP_1505 NC_008253.1 1554668 1556119 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1554668..1556119) Escherichia coli 536 4187930 YP_669414.1 CDS ECP_1506 NC_008253.1 1556346 1557764 R hypothetical protein complement(1556346..1557764) Escherichia coli 536 4187931 YP_669415.1 CDS ECP_1507 NC_008253.1 1557903 1558262 R hypothetical protein complement(1557903..1558262) Escherichia coli 536 4187932 YP_669416.1 CDS ECP_1508 NC_008253.1 1558262 1559188 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1558262..1559188) Escherichia coli 536 4187933 YP_669417.1 CDS ECP_1509 NC_008253.1 1559252 1560640 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(1559252..1560640) Escherichia coli 536 4187934 YP_669418.1 CDS ECP_1510 NC_008253.1 1560741 1561622 D transcriptional regulator YneJ 1560741..1561622 Escherichia coli 536 4187935 YP_669419.1 CDS ECP_1511 NC_008253.1 1561961 1563151 D sugar efflux transporter 1561961..1563151 Escherichia coli 536 4187936 YP_669420.1 CDS ECP_1512 NC_008253.1 1563176 1563841 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1563176..1563841) Escherichia coli 536 4187937 YP_669421.1 CDS ECP_1513 NC_008253.1 1564053 1564487 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1564053..1564487 Escherichia coli 536 4187938 YP_669422.1 CDS ECP_1514 NC_008253.1 1564508 1564891 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1564508..1564891 Escherichia coli 536 4187939 YP_669423.1 CDS ECP_1515 NC_008253.1 1564923 1565141 D hypothetical protein 1564923..1565141 Escherichia coli 536 4187940 YP_669424.1 CDS celA NC_008253.1 1565198 1566637 R converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase complement(1565198..1566637) Escherichia coli 536 4187941 YP_669425.1 CDS ECP_1517 NC_008253.1 1566661 1566972 R hypothetical protein complement(1566661..1566972) Escherichia coli 536 4187942 YP_669426.1 CDS ECP_1518 NC_008253.1 1566980 1567450 D hypothetical protein 1566980..1567450 Escherichia coli 536 4187943 YP_669427.1 CDS ECP_1519 NC_008253.1 1567495 1568394 R O-acetylserine/cysteine export protein complement(1567495..1568394) Escherichia coli 536 4187944 YP_669428.1 CDS ECP_1520 NC_008253.1 1568589 1569776 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1568589..1569776 Escherichia coli 536 4187945 YP_669429.1 CDS ECP_1521 NC_008253.1 1570217 1571107 R hypothetical protein complement(1570217..1571107) Escherichia coli 536 4189391 YP_669430.1 CDS ECP_1522 NC_008253.1 1571614 1573659 R dipeptidyl carboxypeptidase II complement(1571614..1573659) Escherichia coli 536 4189392 YP_669431.1 CDS ECP_1523 NC_008253.1 1573796 1574542 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1573796..1574542 Escherichia coli 536 4189393 YP_669432.1 CDS ECP_1524 NC_008253.1 1574631 1575317 D transcriptional regulator YdfH 1574631..1575317 Escherichia coli 536 4189394 YP_669433.1 CDS ECP_1525 NC_008253.1 1575494 1575697 D hypothetical protein 1575494..1575697 Escherichia coli 536 4189395 YP_669434.1 CDS ECP_1526 NC_008253.1 1575733 1577193 R oxidoreductase YdfI complement(1575733..1577193) Escherichia coli 536 4189396 YP_669435.1 CDS ECP_1527 NC_008253.1 1577282 1578649 R metabolite transport protein YdfJ complement(1577282..1578649) Escherichia coli 536 4189397 YP_669436.1 CDS ECP_1528 NC_008253.1 1578707 1579726 R dehydrogenase complement(1578707..1579726) Escherichia coli 536 4189398 YP_669437.1 CDS ECP_1529 NC_008253.1 1579738 1580952 R starvation sensing protein RspA complement(1579738..1580952) Escherichia coli 536 4189399 YP_669438.1 CDS ECP_1530 NC_008253.1 1581158 1581484 R hypothetical protein complement(1581158..1581484) Escherichia coli 536 4189400 YP_669439.1 CDS ECP_1531 NC_008253.1 1581619 1581960 D hypothetical protein 1581619..1581960 Escherichia coli 536 4189401 YP_669440.1 CDS ECP_1532 NC_008253.1 1581995 1582555 D spermidine N1-acetyltransferase 1581995..1582555 Escherichia coli 536 4189402 YP_669441.1 CDS ECP_1533 NC_008253.1 1582558 1583268 R hypothetical protein complement(1582558..1583268) Escherichia coli 536 4189403 YP_669442.1 CDS ECP_1534 NC_008253.1 1583376 1583681 D hypothetical protein 1583376..1583681 Escherichia coli 536 4189404 YP_669443.1 CDS ECP_1535 NC_008253.1 1583938 1584552 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1583938..1584552 Escherichia coli 536 4189405 YP_669444.1 CDS ECP_1536 NC_008253.1 1584710 1586002 D voltage-gated ClC-type chloride channel ClcB 1584710..1586002 Escherichia coli 536 4189406 YP_669445.1 CDS ECP_1537 NC_008253.1 1585955 1586650 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1585955..1586650) Escherichia coli 536 4189407 YP_669446.1 CDS ECP_1538 NC_008253.1 1586775 1587995 R Mlc protein complement(1586775..1587995) Escherichia coli 536 4189408 YP_669447.1 CDS ECP_1539 NC_008253.1 1588130 1589023 R transcriptional regulator YnfL complement(1588130..1589023) Escherichia coli 536 4189409 YP_669448.1 CDS ECP_1540 NC_008253.1 1589130 1590383 D transporter 1589130..1590383 Escherichia coli 536 4189410 YP_669449.1 CDS ECP_1541 NC_008253.1 1590808 1591116 D required for growth and survival under moderately acid conditions; acid shock protein 1590808..1591116 Escherichia coli 536 4187323 YP_669450.1 CDS ECP_1542 NC_008253.1 1591392 1592213 D protease YdgD 1591392..1592213 Escherichia coli 536 4187324 YP_669451.1 CDS ECP_1543 NC_008253.1 1592252 1592581 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1592252..1592581) Escherichia coli 536 4187325 YP_669452.1 CDS ECP_1544 NC_008253.1 1592568 1592933 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1592568..1592933) Escherichia coli 536 4187326 YP_669453.1 CDS tqsA NC_008253.1 1593345 1594379 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1593345..1594379 Escherichia coli 536 4187327 YP_669454.1 CDS pntB NC_008253.1 1594404 1595792 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1594404..1595792) Escherichia coli 536 4187328 YP_669455.1 CDS pntA NC_008253.1 1595803 1597335 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1595803..1597335) Escherichia coli 536 4187329 YP_669456.1 CDS ECP_1548 NC_008253.1 1597859 1598803 D protein YdgH 1597859..1598803 Escherichia coli 536 4187330 YP_669457.1 CDS ECP_1549 NC_008253.1 1598989 1600371 D arginine/ornithine antiporter 1598989..1600371 Escherichia coli 536 4187331 YP_669458.1 CDS ECP_1550 NC_008253.1 1600408 1601130 D short chain dehydrogenase 1600408..1601130 Escherichia coli 536 4187332 YP_669459.1 CDS ECP_1551 NC_008253.1 1601127 1601462 R hypothetical protein complement(1601127..1601462) Escherichia coli 536 4187333 YP_669460.1 CDS ECP_1552 NC_008253.1 1601591 1602310 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1601591..1602310 Escherichia coli 536 4187334 YP_669461.1 CDS ECP_1553 NC_008253.1 1602314 1603615 D sensor protein RstB 1602314..1603615 Escherichia coli 536 4187335 YP_669462.1 CDS ECP_1554 NC_008253.1 1603691 1604620 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1603691..1604620 Escherichia coli 536 4187336 YP_669463.1 CDS fumC NC_008253.1 1604617 1606020 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1604617..1606020) Escherichia coli 536 4187337 YP_669464.1 CDS ECP_1556 NC_008253.1 1606163 1607809 R class I fumarate hydratase complement(1606163..1607809) Escherichia coli 536 4187338 YP_669465.1 CDS ECP_1557 NC_008253.1 1608008 1609183 D mannose-6-phosphate isomerase 1608008..1609183 Escherichia coli 536 4187339 YP_669466.1 CDS ECP_1558 NC_008253.1 1609284 1610792 D hypothetical protein 1609284..1610792 Escherichia coli 536 4187340 YP_669467.1 CDS ECP_1559 NC_008253.1 1610837 1612102 R outer membrane porin protein complement(1610837..1612102) Escherichia coli 536 4187341 YP_669468.1 CDS ECP_1560 NC_008253.1 1612141 1613514 R glucuronide transporter complement(1612141..1613514) Escherichia coli 536 4187963 YP_669469.1 CDS ECP_1561 NC_008253.1 1613511 1615322 R beta-D-glucuronidase complement(1613511..1615322) Escherichia coli 536 4187964 YP_669470.1 CDS ECP_1562 NC_008253.1 1615712 1616302 R uid operon repressor complement(1615712..1616302) Escherichia coli 536 4187965 YP_669471.1 CDS ECP_1563 NC_008253.1 1616531 1617298 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1616531..1617298) Escherichia coli 536 4187966 YP_669472.1 CDS ECP_1564 NC_008253.1 1617411 1618439 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1617411..1618439) Escherichia coli 536 4187967 YP_669473.1 CDS ECP_1565 NC_008253.1 1618614 1620206 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; PTS system maltose and glucose-specific transporter subunit IICB 1618614..1620206 Escherichia coli 536 4187968 YP_669474.1 CDS ECP_1566 NC_008253.1 1620216 1621388 D MalY protein 1620216..1621388 Escherichia coli 536 4187969 YP_669475.1 CDS ECP_1567 NC_008253.1 1621492 1622493 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1621492..1622493 Escherichia coli 536 4187970 YP_669476.1 CDS ECP_1568 NC_008253.1 1622529 1623569 R oxidoreductase complement(1622529..1623569) Escherichia coli 536 4187971 YP_669477.1 CDS ECP_1569 NC_008253.1 1623782 1623937 D beta-lactam resistance protein 1623782..1623937 Escherichia coli 536 4187972 YP_669478.1 CDS ECP_1570 NC_008253.1 1624210 1624425 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1624210..1624425 Escherichia coli 536 4187973 YP_669479.1 CDS ECP_1571 NC_008253.1 1624511 1624951 D hypothetical protein 1624511..1624951 Escherichia coli 536 4187974 YP_669480.1 CDS ECP_1572 NC_008253.1 1625028 1625609 D Na(+)-translocating NADH-quinone reductase subunit E 1625028..1625609 Escherichia coli 536 4187975 YP_669481.1 CDS ECP_1573 NC_008253.1 1625609 1626187 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1625609..1626187 Escherichia coli 536 4187976 YP_669482.1 CDS ECP_1574 NC_008253.1 1626180 1628504 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1626180..1628504 Escherichia coli 536 4187977 YP_669483.1 CDS rnfD NC_008253.1 1628505 1629563 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1628505..1629563 Escherichia coli 536 4187978 YP_669484.1 CDS ECP_1576 NC_008253.1 1629567 1630187 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1629567..1630187 Escherichia coli 536 4187979 YP_669485.1 CDS ECP_1577 NC_008253.1 1630191 1630886 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1630191..1630886 Escherichia coli 536 4187980 YP_669486.1 CDS ECP_1578 NC_008253.1 1630886 1631521 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1630886..1631521 Escherichia coli 536 4187981 YP_669487.1 CDS tppB NC_008253.1 1632131 1633633 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1632131..1633633 Escherichia coli 536 4187982 YP_669488.1 CDS ECP_1580 NC_008253.1 1633739 1634344 D glutathionine S-transferase 1633739..1634344 Escherichia coli 536 4190462 YP_669489.1 CDS ECP_1581 NC_008253.1 1634388 1635248 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1634388..1635248) Escherichia coli 536 4190463 YP_669490.1 CDS ECP_1584 NC_008253.1 1636713 1637369 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1636713..1637369) Escherichia coli 536 4190466 YP_669491.1 CDS ECP_1585 NC_008253.1 1637428 1637751 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1637428..1637751) Escherichia coli 536 4190467 YP_669492.1 CDS anmK NC_008253.1 1637855 1638964 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1637855..1638964) Escherichia coli 536 4190468 YP_669493.1 CDS ECP_1587 NC_008253.1 1639238 1639705 D outer membrane lipoprotein 1639238..1639705 Escherichia coli 536 4190469 YP_669494.1 CDS ECP_1588 NC_008253.1 1639752 1640192 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1639752..1640192) Escherichia coli 536 4190470 YP_669495.1 CDS ECP_1589 NC_008253.1 1640395 1640622 D hypothetical protein 1640395..1640622 Escherichia coli 536 4190471 YP_669496.1 CDS ECP_1590 NC_008253.1 1640625 1641482 D hypothetical protein 1640625..1641482 Escherichia coli 536 4190472 YP_669497.1 CDS ECP_1591 NC_008253.1 1641482 1643494 D hypothetical protein 1641482..1643494 Escherichia coli 536 4190473 YP_669498.1 CDS ECP_1592 NC_008253.1 1643495 1644031 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1643495..1644031) Escherichia coli 536 4190474 YP_669499.1 CDS ECP_1593 NC_008253.1 1644097 1644993 R aldo/keto reductase complement(1644097..1644993) Escherichia coli 536 4190475 YP_669500.1 CDS ECP_1594 NC_008253.1 1645042 1645419 R hypothetical protein complement(1645042..1645419) Escherichia coli 536 4190476 YP_669501.1 CDS ECP_1595 NC_008253.1 1645384 1645983 D transcriptional regulator YdhM 1645384..1645983 Escherichia coli 536 4190477 YP_669502.1 CDS ECP_1596 NC_008253.1 1646020 1647117 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1646020..1647117 Escherichia coli 536 4190478 YP_669503.1 CDS ECP_1597 NC_008253.1 1647198 1647605 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1647198..1647605 Escherichia coli 536 4190407 YP_669504.1 CDS ECP_1598 NC_008253.1 1647708 1648355 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1647708..1648355 Escherichia coli 536 4190408 YP_669505.1 CDS ECP_1599 NC_008253.1 1648727 1649074 R hypothetical protein complement(1648727..1649074) Escherichia coli 536 4190409 YP_669506.1 CDS ECP_1600 NC_008253.1 1649409 1650224 D lipoprotein 1649409..1650224 Escherichia coli 536 4190410 YP_669507.1 CDS ECP_1601 NC_008253.1 1650352 1650933 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1650352..1650933 Escherichia coli 536 4190411 YP_669508.1 CDS ECP_1602 NC_008253.1 1651079 1652248 R transport transmembrane protein complement(1651079..1652248) Escherichia coli 536 4190412 YP_669509.1 CDS ECP_1603 NC_008253.1 1652414 1652503 R hypothetical protein complement(1652414..1652503) Escherichia coli 536 4190413 YP_669510.1 CDS ECP_1604 NC_008253.1 1652590 1652814 D hypothetical protein 1652590..1652814 Escherichia coli 536 4190414 YP_669511.1 CDS ECP_1605 NC_008253.1 1652802 1653827 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1652802..1653827 Escherichia coli 536 4190415 YP_669512.1 CDS ECP_1606 NC_008253.1 1653824 1654756 R DNA-binding transcriptional regulator complement(1653824..1654756) Escherichia coli 536 4190416 YP_669513.1 CDS ECP_1607 NC_008253.1 1654869 1656080 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1654869..1656080 Escherichia coli 536 4190417 YP_669514.1 CDS ECP_1608 NC_008253.1 1656371 1657519 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1656371..1657519 Escherichia coli 536 4190418 YP_669515.1 CDS ECP_1609 NC_008253.1 1657559 1658200 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1657559..1658200) Escherichia coli 536 4190419 YP_669516.1 CDS ECP_1610 NC_008253.1 1658415 1659788 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1658415..1659788 Escherichia coli 536 4190420 YP_669517.1 CDS ECP_1611 NC_008253.1 1659829 1661085 R hypothetical protein complement(1659829..1661085) Escherichia coli 536 4190421 YP_669518.1 CDS ECP_1614 NC_008253.1 1661660 1661965 D hypothetical protein 1661660..1661965 Escherichia coli 536 4190537 YP_669519.1 CDS ECP_1615 NC_008253.1 1662091 1663701 D hypothetical protein 1662091..1663701 Escherichia coli 536 4190538 YP_669520.1 CDS ECP_1616 NC_008253.1 1663707 1664471 R hypothetical protein complement(1663707..1664471) Escherichia coli 536 4190539 YP_669521.1 CDS ECP_1617 NC_008253.1 1664523 1665308 R PhsC-like protein complement(1664523..1665308) Escherichia coli 536 4190540 YP_669522.1 CDS ECP_1618 NC_008253.1 1665305 1665973 R ferredoxin-like protein YdhX complement(1665305..1665973) Escherichia coli 536 4190541 YP_669523.1 CDS ECP_1619 NC_008253.1 1666037 1666675 R hypothetical protein complement(1666037..1666675) Escherichia coli 536 4190542 YP_669524.1 CDS ECP_1620 NC_008253.1 1666688 1668790 R oxidoreductase complement(1666688..1668790) Escherichia coli 536 4190543 YP_669525.1 CDS ECP_1621 NC_008253.1 1668811 1669437 R hypothetical protein complement(1668811..1669437) Escherichia coli 536 4190544 YP_669526.1 CDS ECP_1622 NC_008253.1 1669893 1670102 R hypothetical protein complement(1669893..1670102) Escherichia coli 536 4190545 YP_669527.1 CDS ECP_1623 NC_008253.1 1670443 1672071 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1670443..1672071 Escherichia coli 536 4190546 YP_669528.1 CDS ECP_1624 NC_008253.1 1672382 1672618 D major outer membrane lipoprotein 1672382..1672618 Escherichia coli 536 4190547 YP_669529.1 CDS ECP_1625 NC_008253.1 1672681 1673685 R hypothetical protein complement(1672681..1673685) Escherichia coli 536 4190548 YP_669530.1 CDS ECP_1626 NC_008253.1 1673834 1674250 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1673834..1674250) Escherichia coli 536 4190549 YP_669531.1 CDS ECP_1627 NC_008253.1 1674263 1675483 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1674263..1675483) Escherichia coli 536 4190550 YP_669532.1 CDS ECP_1628 NC_008253.1 1675480 1676751 R required for stability of iron-sulfur component of FhuF; with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1675480..1676751) Escherichia coli 536 4190551 YP_669533.1 CDS sufC NC_008253.1 1676726 1677472 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1676726..1677472) Escherichia coli 536 4190552 YP_669534.1 CDS ECP_1630 NC_008253.1 1677482 1678969 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1677482..1678969) Escherichia coli 536 4190553 YP_669535.1 CDS sufA NC_008253.1 1678978 1679346 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1678978..1679346) Escherichia coli 536 4190554 YP_669536.1 CDS ECP_1632 NC_008253.1 1679895 1680083 R hypothetical protein complement(1679895..1680083) Escherichia coli 536 4190555 YP_669537.1 CDS ECP_1633 NC_008253.1 1680183 1680593 R hypothetical protein complement(1680183..1680593) Escherichia coli 536 4190556 YP_669538.1 CDS ECP_1634 NC_008253.1 1680590 1683646 R oxidase complement(1680590..1683646) Escherichia coli 536 4188394 YP_669539.1 CDS ECP_1635 NC_008253.1 1683860 1684972 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1683860..1684972 Escherichia coli 536 4188395 YP_669540.1 CDS ECP_1636 NC_008253.1 1685401 1685757 D hypothetical protein 1685401..1685757 Escherichia coli 536 4188396 YP_669541.1 CDS ECP_1637 NC_008253.1 1685857 1687071 D transporter 1685857..1687071 Escherichia coli 536 4188397 YP_669542.1 CDS ECP_1638 NC_008253.1 1687298 1688563 D transporter 1687298..1688563 Escherichia coli 536 4188398 YP_669543.1 CDS ECP_1639 NC_008253.1 1688575 1689441 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1688575..1689441 Escherichia coli 536 4188399 YP_669544.1 CDS aroD NC_008253.1 1689472 1690230 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1689472..1690230 Escherichia coli 536 4188400 YP_669545.1 CDS ECP_1641 NC_008253.1 1690375 1691970 D hypothetical protein 1690375..1691970 Escherichia coli 536 4188401 YP_669546.1 CDS ECP_1642 NC_008253.1 1691981 1693135 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1691981..1693135 Escherichia coli 536 4188402 YP_669547.1 CDS ECP_1643 NC_008253.1 1693178 1694089 R transcriptional regulator YdiP complement(1693178..1694089) Escherichia coli 536 4188403 YP_669548.1 CDS ECP_1644 NC_008253.1 1694405 1695169 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1694405..1695169 Escherichia coli 536 4188404 YP_669549.1 CDS ECP_1645 NC_008253.1 1695189 1696127 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1695189..1696127 Escherichia coli 536 4188405 YP_669550.1 CDS ECP_1646 NC_008253.1 1696182 1697471 D hypothetical protein 1696182..1697471 Escherichia coli 536 4188406 YP_669551.1 CDS ECP_1647 NC_008253.1 1697468 1697761 D ferredoxin-like protein YdiT 1697468..1697761 Escherichia coli 536 4188407 YP_669552.1 CDS ECP_1648 NC_008253.1 1697764 1699464 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1697764..1699464 Escherichia coli 536 4188408 YP_669553.1 CDS ECP_1649 NC_008253.1 1699521 1701899 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1699521..1701899) Escherichia coli 536 4188409 YP_669554.1 CDS ECP_1650 NC_008253.1 1701953 1702120 R hypothetical protein complement(1701953..1702120) Escherichia coli 536 4188410 YP_669555.1 CDS ECP_1651 NC_008253.1 1702232 1703065 D hypothetical protein 1702232..1703065 Escherichia coli 536 4188411 YP_669556.1 CDS ECP_1652 NC_008253.1 1703222 1704268 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1703222..1704268 Escherichia coli 536 4188412 YP_669557.1 CDS ECP_1653 NC_008253.1 1704400 1704591 D hypothetical protein 1704400..1704591 Escherichia coli 536 4190837 YP_669558.1 CDS ECP_1654 NC_008253.1 1704595 1706031 R hypothetical protein complement(1704595..1706031) Escherichia coli 536 4190838 YP_669559.1 CDS ECP_1655 NC_008253.1 1706094 1706807 R hypothetical protein complement(1706094..1706807) Escherichia coli 536 4190839 YP_669560.1 CDS ECP_1656 NC_008253.1 1707054 1707518 R lipoprotein NlpC complement(1707054..1707518) Escherichia coli 536 4190840 YP_669561.1 CDS ECP_1657 NC_008253.1 1707596 1708345 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1707596..1708345) Escherichia coli 536 4190841 YP_669562.1 CDS btuE NC_008253.1 1708345 1708896 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(1708345..1708896) Escherichia coli 536 4190842 YP_669563.1 CDS ECP_1659 NC_008253.1 1708958 1709938 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1708958..1709938) Escherichia coli 536 4190843 YP_669564.1 CDS ihfA NC_008253.1 1710039 1710338 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1710039..1710338) Escherichia coli 536 4190844 YP_669565.1 CDS pheT NC_008253.1 1710343 1712730 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1710343..1712730) Escherichia coli 536 4190845 YP_669566.1 CDS pheS NC_008253.1 1712745 1713728 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1712745..1713728) Escherichia coli 536 4190846 YP_669567.1 CDS rplT NC_008253.1 1714179 1714535 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1714179..1714535) Escherichia coli 536 4190847 YP_669568.1 CDS rpmI NC_008253.1 1714588 1714785 R 50S ribosomal protein L35 complement(1714588..1714785) Escherichia coli 536 4190848 YP_669569.1 CDS infC NC_008253.1 1714882 1715316 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1714882..1715316) Escherichia coli 536 4190849 YP_669570.1 CDS ECP_1666 NC_008253.1 1715428 1717356 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1715428..1717356) Escherichia coli 536 4190850 YP_669571.1 CDS ECP_1667 NC_008253.1 1718042 1718407 D hypothetical protein 1718042..1718407 Escherichia coli 536 4190851 YP_669572.1 CDS ECP_1668 NC_008253.1 1718362 1718763 D hypothetical protein 1718362..1718763 Escherichia coli 536 4190852 YP_669573.1 CDS ECP_1669 NC_008253.1 1719241 1719999 R hypothetical protein complement(1719241..1719999) Escherichia coli 536 4190853 YP_669574.1 CDS ECP_1670 NC_008253.1 1720286 1721215 D 6-phosphofructokinase 1720286..1721215 Escherichia coli 536 4190854 YP_669575.1 CDS ECP_1671 NC_008253.1 1721316 1721606 D hypothetical protein 1721316..1721606 Escherichia coli 536 4190855 YP_669576.1 CDS ECP_1672 NC_008253.1 1721712 1722572 D fructosamine kinase 1721712..1722572 Escherichia coli 536 4190856 YP_669577.1 CDS ECP_1673 NC_008253.1 1722613 1723149 R hypothetical protein complement(1722613..1723149) Escherichia coli 536 4191307 YP_669578.1 CDS ECP_1674 NC_008253.1 1723296 1723964 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1723296..1723964 Escherichia coli 536 4191308 YP_669579.1 CDS ECP_1675 NC_008253.1 1724128 1724718 D hypothetical protein 1724128..1724718 Escherichia coli 536 4191309 YP_669580.1 CDS ECP_1676 NC_008253.1 1724851 1726242 D sodium:dicarboxylate symporter YdjN 1724851..1726242 Escherichia coli 536 4191310 YP_669581.1 CDS ECP_1677 NC_008253.1 1726289 1726531 R cell division modulator complement(1726289..1726531) Escherichia coli 536 4191311 YP_669582.1 CDS katE NC_008253.1 1726735 1728996 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1726735..1728996 Escherichia coli 536 4191312 YP_669583.1 CDS ECP_1679 NC_008253.1 1729043 1729801 R hypothetical protein complement(1729043..1729801) Escherichia coli 536 4191313 YP_669584.1 CDS ECP_1680 NC_008253.1 1729814 1731166 R 6-phospho-beta-glucosidase complement(1729814..1731166) Escherichia coli 536 4191314 YP_669585.1 CDS ECP_1681 NC_008253.1 1731270 1732109 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1731270..1732109) Escherichia coli 536 4191315 YP_669586.1 CDS ECP_1682 NC_008253.1 1732120 1732470 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1732120..1732470) Escherichia coli 536 4191316 YP_669587.1 CDS ECP_1683 NC_008253.1 1732521 1733879 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1732521..1733879) Escherichia coli 536 4191317 YP_669588.1 CDS ECP_1684 NC_008253.1 1733964 1734284 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1733964..1734284) Escherichia coli 536 4191318 YP_669589.1 CDS ECP_1685 NC_008253.1 1734584 1734922 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1734584..1734922) Escherichia coli 536 4191319 YP_669590.1 CDS nadE NC_008253.1 1735124 1735951 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1735124..1735951 Escherichia coli 536 4191320 YP_669591.1 CDS ECP_1687 NC_008253.1 1736181 1737068 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1736181..1737068 Escherichia coli 536 4191321 YP_669592.1 CDS ECP_1688 NC_008253.1 1737028 1737603 R hypothetical protein complement(1737028..1737603) Escherichia coli 536 4191322 YP_669593.1 CDS ECP_1689 NC_008253.1 1737806 1738291 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(1737806..1738291) Escherichia coli 536 4191323 YP_669594.1 CDS ECP_1690 NC_008253.1 1738621 1739589 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1738621..1739589) Escherichia coli 536 4191324 YP_669595.1 CDS ECP_1691 NC_008253.1 1739582 1740925 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1739582..1740925) Escherichia coli 536 4191325 YP_669596.1 CDS astD NC_008253.1 1740922 1742400 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1740922..1742400) Escherichia coli 536 4188432 YP_669597.1 CDS ECP_1693 NC_008253.1 1742397 1743431 R arginine succinyltransferase complement(1742397..1743431) Escherichia coli 536 4188433 YP_669598.1 CDS ECP_1694 NC_008253.1 1743428 1744648 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1743428..1744648) Escherichia coli 536 4188434 YP_669599.1 CDS ECP_1695 NC_008253.1 1745082 1745900 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1745082..1745900 Escherichia coli 536 4188435 YP_669600.1 CDS ECP_1696 NC_008253.1 1746067 1746777 D hypothetical protein 1746067..1746777 Escherichia coli 536 4188436 YP_669601.1 CDS ECP_1697 NC_008253.1 1746782 1747459 D hypothetical protein 1746782..1747459 Escherichia coli 536 4188437 YP_669602.1 CDS ECP_1698 NC_008253.1 1747473 1748180 D hypothetical protein 1747473..1748180 Escherichia coli 536 4188438 YP_669603.1 CDS ECP_1699 NC_008253.1 1748180 1748728 D hypothetical protein 1748180..1748728 Escherichia coli 536 4188439 YP_669604.1 CDS ECP_1700 NC_008253.1 1748738 1749904 D ABC transporter substrate-binding protein 1748738..1749904 Escherichia coli 536 4188440 YP_669605.1 CDS ECP_1701 NC_008253.1 1749877 1751412 D ABC transporter permease 1749877..1751412 Escherichia coli 536 4188441 YP_669606.1 CDS ECP_1702 NC_008253.1 1751412 1752065 D ABC transporter ATP-binding protein 1751412..1752065 Escherichia coli 536 4188442 YP_669607.1 CDS ECP_1703 NC_008253.1 1752368 1753441 D thiosulfate sulfurtransferase 1752368..1753441 Escherichia coli 536 4188443 YP_669608.1 CDS ECP_1704 NC_008253.1 1753450 1754070 R hypothetical protein complement(1753450..1754070) Escherichia coli 536 4188444 YP_669609.1 CDS ECP_1705 NC_008253.1 1754157 1754564 D pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1754157..1754564 Escherichia coli 536 4188445 YP_669610.1 CDS ECP_1706 NC_008253.1 1754530 1754802 R hypothetical protein complement(1754530..1754802) Escherichia coli 536 4188446 YP_669611.1 CDS ECP_1707 NC_008253.1 1755038 1756381 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1755038..1756381 Escherichia coli 536 4188447 YP_669612.1 CDS ECP_1708 NC_008253.1 1756437 1758380 R hypothetical protein complement(1756437..1758380) Escherichia coli 536 4188448 YP_669613.1 CDS ECP_1709 NC_008253.1 1758408 1760357 R hypothetical protein complement(1758408..1760357) Escherichia coli 536 4188449 YP_669614.1 CDS ECP_1710 NC_008253.1 1760354 1762054 R chaperone protein HscC complement(1760354..1762054) Escherichia coli 536 4188450 YP_669615.1 CDS ECP_1711 NC_008253.1 1762422 1764368 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1762422..1764368) Escherichia coli 536 4188451 YP_669616.1 CDS ECP_1712 NC_008253.1 1764373 1765416 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1764373..1765416) Escherichia coli 536 4191897 YP_669617.1 CDS ECP_1713 NC_008253.1 1765533 1766084 R hypothetical protein complement(1765533..1766084) Escherichia coli 536 4191898 YP_669618.1 CDS ECP_1714 NC_008253.1 1766245 1768101 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1766245..1768101 Escherichia coli 536 4191899 YP_669619.1 CDS ansA NC_008253.1 1768268 1769284 D converts asparagine to aspartate and ammonia; asparaginase 1768268..1769284 Escherichia coli 536 4191900 YP_669620.1 CDS ECP_1716 NC_008253.1 1769295 1769936 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1769295..1769936 Escherichia coli 536 4191901 YP_669621.1 CDS ECP_1717 NC_008253.1 1770029 1771387 R metabolite transport protein YdjE complement(1770029..1771387) Escherichia coli 536 4191902 YP_669622.1 CDS ECP_1718 NC_008253.1 1771505 1772263 R transcriptional regulator YdjF complement(1771505..1772263) Escherichia coli 536 4191903 YP_669623.1 CDS ECP_1719 NC_008253.1 1772400 1773380 R oxidoreductase YdjG complement(1772400..1773380) Escherichia coli 536 4191904 YP_669624.1 CDS ECP_1720 NC_008253.1 1773390 1774358 R sugar kinase complement(1773390..1774358) Escherichia coli 536 4191905 YP_669625.1 CDS ECP_1721 NC_008253.1 1774342 1775178 R hypothetical protein complement(1774342..1775178) Escherichia coli 536 4191906 YP_669626.1 CDS ECP_1722 NC_008253.1 1775199 1776203 R zinc-type alcohol dehydrogenase-like protein YdjJ complement(1775199..1776203) Escherichia coli 536 4191907 YP_669627.1 CDS ECP_1723 NC_008253.1 1776259 1777638 R metabolite transport protein YdjK complement(1776259..1777638) Escherichia coli 536 4191908 YP_669628.1 CDS ECP_1724 NC_008253.1 1777665 1778741 R zinc-type alcohol dehydrogenase-like protein YdjL complement(1777665..1778741) Escherichia coli 536 4191909 YP_669629.1 CDS ECP_1725 NC_008253.1 1779111 1779383 R hypothetical protein complement(1779111..1779383) Escherichia coli 536 4191910 YP_669630.1 CDS ECP_1726 NC_008253.1 1779425 1779838 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1779425..1779838) Escherichia coli 536 4191911 YP_669631.1 CDS ECP_1727 NC_008253.1 1780180 1781175 D glyceraldehyde 3-phosphate dehydrogenase A 1780180..1781175 Escherichia coli 536 4191912 YP_669632.1 CDS ECP_1728 NC_008253.1 1781259 1782143 D aldose 1-epimerase 1781259..1782143 Escherichia coli 536 4191913 YP_669633.1 CDS ECP_1729 NC_008253.1 1782194 1783048 R hypothetical protein complement(1782194..1783048) Escherichia coli 536 4191914 YP_669634.1 CDS ECP_1730 NC_008253.1 1783138 1783884 R MltA-interacting protein complement(1783138..1783884) Escherichia coli 536 4191915 YP_669635.1 CDS ECP_1731 NC_008253.1 1784320 1786254 D hypothetical protein 1784320..1786254 Escherichia coli 536 4191956 YP_669636.1 CDS ECP_1732 NC_008253.1 1786367 1787650 D hypothetical protein 1786367..1787650 Escherichia coli 536 4191957 YP_669637.1 CDS ECP_1733 NC_008253.1 1787797 1789272 D hypothetical protein 1787797..1789272 Escherichia coli 536 4191958 YP_669638.1 CDS ECP_1734 NC_008253.1 1789453 1790943 D hypothetical protein 1789453..1790943 Escherichia coli 536 4191959 YP_669639.1 CDS ECP_1735 NC_008253.1 1790986 1791489 D hypothetical protein 1790986..1791489 Escherichia coli 536 4191960 YP_669640.1 CDS ECP_1736 NC_008253.1 1791764 1792210 D hypothetical protein 1791764..1792210 Escherichia coli 536 4191961 YP_669641.1 CDS ECP_1737 NC_008253.1 1792167 1792988 R transcriptional regulator YeaM complement(1792167..1792988) Escherichia coli 536 4191962 YP_669642.1 CDS ECP_1738 NC_008253.1 1793085 1794266 D transporter 1793085..1794266 Escherichia coli 536 4191963 YP_669643.1 CDS ECP_1739 NC_008253.1 1794321 1794668 D hypothetical protein 1794321..1794668 Escherichia coli 536 4191964 YP_669644.1 CDS ECP_1740 NC_008253.1 1794690 1794944 R hypothetical protein complement(1794690..1794944) Escherichia coli 536 4191965 YP_669645.1 CDS ECP_1741 NC_008253.1 1795127 1796152 D hypothetical protein 1795127..1796152 Escherichia coli 536 4191966 YP_669646.1 CDS ECP_1742 NC_008253.1 1796419 1796667 R hypothetical protein complement(1796419..1796667) Escherichia coli 536 4191967 YP_669647.1 CDS ECP_1743 NC_008253.1 1796815 1796997 R hypothetical protein complement(1796815..1796997) Escherichia coli 536 4191968 YP_669648.1 CDS ECP_1744 NC_008253.1 1797001 1797360 R hypothetical protein complement(1797001..1797360) Escherichia coli 536 4191969 YP_669649.1 CDS ECP_1745 NC_008253.1 1797533 1798171 R leucine export protein LeuE complement(1797533..1798171) Escherichia coli 536 4191970 YP_669650.1 CDS ECP_1746 NC_008253.1 1798298 1798630 R hypothetical protein complement(1798298..1798630) Escherichia coli 536 4191971 YP_669651.1 CDS ECP_1747 NC_008253.1 1798714 1799829 R ribonuclease D complement(1798714..1799829) Escherichia coli 536 4191972 YP_669652.1 CDS ECP_1748 NC_008253.1 1799911 1801629 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1799911..1801629) Escherichia coli 536 4191973 YP_669653.1 CDS ECP_1749 NC_008253.1 1801801 1802382 R Slp family outer membrane lipoprotein complement(1801801..1802382) Escherichia coli 536 4191974 YP_669654.1 CDS ECP_1750 NC_008253.1 1802422 1803117 R protease YeaZ complement(1802422..1803117) Escherichia coli 536 4191975 YP_669655.1 CDS ECP_1751 NC_008253.1 1803175 1805085 R ATP-dependent helicase YoaA complement(1803175..1805085) Escherichia coli 536 4188375 YP_669656.1 CDS ECP_1752 NC_008253.1 1805214 1805561 D hypothetical protein 1805214..1805561 Escherichia coli 536 4188376 YP_669657.1 CDS ECP_1753 NC_008253.1 1805983 1806282 D hypothetical protein 1805983..1806282 Escherichia coli 536 4188377 YP_669658.1 CDS ECP_1754 NC_008253.1 1806402 1806581 R hypothetical protein complement(1806402..1806581) Escherichia coli 536 4188378 YP_669659.1 CDS ECP_1755 NC_008253.1 1806655 1808016 D para-aminobenzoate synthase component I 1806655..1808016 Escherichia coli 536 4188379 YP_669660.1 CDS ECP_1756 NC_008253.1 1808020 1808598 D hypothetical protein 1808020..1808598 Escherichia coli 536 4188380 YP_669661.1 CDS ECP_1757 NC_008253.1 1808782 1810146 D L-serine dehydratase 1 1808782..1810146 Escherichia coli 536 4188381 YP_669662.1 CDS ECP_1758 NC_008253.1 1810277 1811875 D hypothetical protein 1810277..1811875 Escherichia coli 536 4188382 YP_669663.1 CDS ECP_1759 NC_008253.1 1811879 1813435 R hypothetical protein complement(1811879..1813435) Escherichia coli 536 4188383 YP_669664.1 CDS ECP_1760 NC_008253.1 1813898 1814869 D PTS system mannose-specific transporter subunit IIAB 1813898..1814869 Escherichia coli 536 4188384 YP_669665.1 CDS ECP_1761 NC_008253.1 1814932 1815732 D PTS system mannose-specific transporter subunit IIC 1814932..1815732 Escherichia coli 536 4188385 YP_669666.1 CDS ECP_1762 NC_008253.1 1815745 1816596 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; mannose-specific PTS system protein IID 1815745..1816596 Escherichia coli 536 4188386 YP_669667.1 CDS ECP_1763 NC_008253.1 1816651 1817109 D hypothetical protein 1816651..1817109 Escherichia coli 536 4188387 YP_669668.1 CDS ECP_1764 NC_008253.1 1817538 1818104 D membrane protein YebN; hypothetical protein 1817538..1818104 Escherichia coli 536 4188388 YP_669669.1 CDS rrmA NC_008253.1 1818101 1818910 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase complement(1818101..1818910) Escherichia coli 536 4188389 YP_669670.1 CDS ECP_1766 NC_008253.1 1819076 1819285 R cold shock-like protein CspC complement(1819076..1819285) Escherichia coli 536 4188390 YP_669671.1 CDS ECP_1767 NC_008253.1 1819298 1819441 R hypothetical protein complement(1819298..1819441) Escherichia coli 536 4188391 YP_669672.1 CDS ECP_1768 NC_008253.1 1820111 1820398 R hypothetical protein complement(1820111..1820398) Escherichia coli 536 4188392 YP_669674.1 CDS ECP_1770 NC_008253.1 1820775 1821014 D hypothetical protein 1820775..1821014 Escherichia coli 536 4191780 YP_669675.1 CDS ECP_1771 NC_008253.1 1821158 1821949 R transcriptional regulator KdgR complement(1821158..1821949) Escherichia coli 536 4191781 YP_669676.1 CDS ECP_1772 NC_008253.1 1822126 1823499 D transporter 1822126..1823499 Escherichia coli 536 4191782 YP_669677.1 CDS ECP_1773 NC_008253.1 1823545 1824426 R metalloprotease; heat shock protein HtpX complement(1823545..1824426) Escherichia coli 536 4191783 YP_669678.1 CDS ECP_1774 NC_008253.1 1824618 1826666 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1824618..1826666) Escherichia coli 536 4191784 YP_669679.1 CDS ECP_1775 NC_008253.1 1826686 1827384 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(1826686..1827384) Escherichia coli 536 4191785 YP_669680.1 CDS ECP_1776 NC_008253.1 1827481 1827978 R GAF domain-containing protein complement(1827481..1827978) Escherichia coli 536 4191786 YP_669681.1 CDS ECP_1777 NC_008253.1 1828108 1829391 D hypothetical protein 1828108..1829391 Escherichia coli 536 4191787 YP_669682.1 CDS ECP_1778 NC_008253.1 1829360 1831993 D hypothetical protein 1829360..1831993 Escherichia coli 536 4191788 YP_669683.1 CDS yebU NC_008253.1 1832067 1833512 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1832067..1833512 Escherichia coli 536 4191789 YP_669684.1 CDS ECP_1780 NC_008253.1 1833630 1833866 D hypothetical protein 1833630..1833866 Escherichia coli 536 4191790 YP_669685.1 CDS ECP_1781 NC_008253.1 1833971 1834162 D hypothetical protein 1833971..1834162 Escherichia coli 536 4191791 YP_669686.1 CDS pphA NC_008253.1 1834163 1834819 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(1834163..1834819) Escherichia coli 536 4191792 YP_669687.1 CDS ECP_1783 NC_008253.1 1835214 1835555 R hypothetical protein complement(1835214..1835555) Escherichia coli 536 4191793 YP_669688.1 CDS ECP_1784 NC_008253.1 1835568 1836440 R hypothetical protein complement(1835568..1836440) Escherichia coli 536 4191794 YP_669689.1 CDS ECP_1785 NC_008253.1 1836444 1836818 R hypothetical protein complement(1836444..1836818) Escherichia coli 536 4191795 YP_669690.1 CDS ECP_1786 NC_008253.1 1836870 1837187 D DNA polymerase III subunit theta 1836870..1837187 Escherichia coli 536 4191796 YP_669691.1 CDS ECP_1787 NC_008253.1 1837290 1837946 D hypothetical protein 1837290..1837946 Escherichia coli 536 4191797 YP_669692.1 CDS ECP_1788 NC_008253.1 1837970 1838632 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1837970..1838632 Escherichia coli 536 4191798 YP_669693.1 CDS ECP_1789 NC_008253.1 1838629 1840689 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(1838629..1840689) Escherichia coli 536 4191799 YP_669694.1 CDS ECP_1790 NC_008253.1 1840898 1841557 R hypothetical protein complement(1840898..1841557) Escherichia coli 536 4189811 YP_669695.1 CDS ECP_1791 NC_008253.1 1841884 1842240 R secreted protein; unknown function; hypothetical protein complement(1841884..1842240) Escherichia coli 536 4189812 YP_669696.1 CDS ECP_1792 NC_008253.1 1842307 1842597 R DNA damage-inducible protein YebG complement(1842307..1842597) Escherichia coli 536 4189813 YP_669697.1 CDS purT NC_008253.1 1842731 1843909 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1842731..1843909 Escherichia coli 536 4189814 YP_669698.1 CDS ECP_1794 NC_008253.1 1843965 1844606 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1843965..1844606) Escherichia coli 536 4189815 YP_669699.1 CDS ECP_1795 NC_008253.1 1844643 1846454 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1844643..1846454) Escherichia coli 536 4189816 YP_669700.1 CDS ECP_1796 NC_008253.1 1846689 1848164 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1846689..1848164) Escherichia coli 536 4189817 YP_669701.1 CDS ECP_1797 NC_008253.1 1848502 1849371 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1848502..1849371 Escherichia coli 536 4189818 YP_669702.1 CDS ECP_1798 NC_008253.1 1849499 1850941 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1849499..1850941 Escherichia coli 536 4189819 YP_669703.1 CDS ECP_1799 NC_008253.1 1851073 1852044 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(1851073..1852044) Escherichia coli 536 4189820 YP_669704.1 CDS ECP_1800 NC_008253.1 1852163 1853485 R hypothetical protein complement(1852163..1853485) Escherichia coli 536 4189821 YP_669705.1 CDS znuA NC_008253.1 1853501 1854487 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(1853501..1854487) Escherichia coli 536 4189822 YP_669706.1 CDS znuC NC_008253.1 1854512 1855267 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1854512..1855267 Escherichia coli 536 4189823 YP_669707.1 CDS znuB NC_008253.1 1855264 1856049 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1855264..1856049 Escherichia coli 536 4189824 YP_669708.1 CDS ruvB NC_008253.1 1856197 1857207 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1856197..1857207) Escherichia coli 536 4189825 YP_669709.1 CDS ruvA NC_008253.1 1857216 1857827 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1857216..1857827) Escherichia coli 536 4189826 YP_669710.1 CDS ECP_1806 NC_008253.1 1858104 1858706 D hypothetical protein 1858104..1858706 Escherichia coli 536 4189827 YP_669711.1 CDS ruvC NC_008253.1 1858708 1859229 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1858708..1859229) Escherichia coli 536 4189828 YP_669712.1 CDS ECP_1808 NC_008253.1 1859264 1860004 R hypothetical protein complement(1859264..1860004) Escherichia coli 536 4189829 YP_669713.1 CDS ntpA NC_008253.1 1860033 1860476 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(1860033..1860476) Escherichia coli 536 4188772 YP_669714.1 CDS aspS NC_008253.1 1860478 1862250 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1860478..1862250) Escherichia coli 536 4188773 YP_669715.1 CDS ECP_1811 NC_008253.1 1862560 1863126 D hypothetical protein 1862560..1863126 Escherichia coli 536 4188774 YP_669716.1 CDS ECP_1812 NC_008253.1 1863123 1863941 D hypothetical protein 1863123..1863941 Escherichia coli 536 4188775 YP_669717.1 CDS ECP_1813 NC_008253.1 1863994 1864389 D hypothetical protein 1863994..1864389 Escherichia coli 536 4188776 YP_669718.1 CDS ECP_1814 NC_008253.1 1864430 1865173 D protein YecO 1864430..1865173 Escherichia coli 536 4188777 YP_669719.1 CDS ECP_1815 NC_008253.1 1865170 1866141 D hypothetical protein 1865170..1866141 Escherichia coli 536 4188778 YP_669720.1 CDS ECP_1818 NC_008253.1 1868760 1869860 R cytochrome c-type protein TorY complement(1868760..1869860) Escherichia coli 536 4188781 YP_669721.1 CDS ECP_1819 NC_008253.1 1870248 1870994 R copper homeostasis protein CutC complement(1870248..1870994) Escherichia coli 536 4188782 YP_669722.1 CDS ECP_1820 NC_008253.1 1871008 1871574 R hypothetical protein complement(1871008..1871574) Escherichia coli 536 4188783 YP_669723.1 CDS ECP_1821 NC_008253.1 1871577 1871756 R hypothetical protein complement(1871577..1871756) Escherichia coli 536 4188784 YP_669724.1 CDS argS NC_008253.1 1871790 1873523 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1871790..1873523 Escherichia coli 536 4188785 YP_669725.1 CDS ECP_1823 NC_008253.1 1873576 1873968 R flagellar protein FlhE complement(1873576..1873968) Escherichia coli 536 4188786 YP_669726.1 CDS flhA NC_008253.1 1873968 1876046 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(1873968..1876046) Escherichia coli 536 4188787 YP_669727.1 CDS flhB NC_008253.1 1876039 1877187 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(1876039..1877187) Escherichia coli 536 4188788 YP_669728.1 CDS ECP_1826 NC_008253.1 1877396 1878040 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(1877396..1878040) Escherichia coli 536 4189528 YP_669729.1 CDS ECP_1827 NC_008253.1 1878051 1878440 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(1878051..1878440) Escherichia coli 536 4189529 YP_669730.1 CDS ECP_1828 NC_008253.1 1878455 1879504 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(1878455..1879504) Escherichia coli 536 4189530 YP_669731.1 CDS ECP_1829 NC_008253.1 1879507 1880367 R methylates the MCP; chemotaxis methyltransferase CheR complement(1879507..1880367) Escherichia coli 536 4189531 YP_669732.1 CDS ECP_1830 NC_008253.1 1880658 1882319 R methyl-accepting chemotaxis protein II complement(1880658..1882319) Escherichia coli 536 4189532 YP_669733.1 CDS ECP_1831 NC_008253.1 1882464 1882967 R purine-binding chemotaxis protein complement(1882464..1882967) Escherichia coli 536 4189533 YP_669734.1 CDS ECP_1832 NC_008253.1 1882988 1884946 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(1882988..1884946) Escherichia coli 536 4189534 YP_669735.1 CDS motB NC_008253.1 1884957 1885883 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(1884957..1885883) Escherichia coli 536 4189535 YP_669736.1 CDS ECP_1834 NC_008253.1 1885880 1886767 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(1885880..1886767) Escherichia coli 536 4189536 YP_669737.1 CDS ECP_1835 NC_008253.1 1886894 1887472 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(1886894..1887472) Escherichia coli 536 4189537 YP_669738.1 CDS ECP_1836 NC_008253.1 1887475 1887825 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(1887475..1887825) Escherichia coli 536 4189538 YP_669739.1 CDS ECP_1837 NC_008253.1 1888605 1889033 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1888605..1889033 Escherichia coli 536 4189539 YP_669740.1 CDS ECP_1838 NC_008253.1 1889040 1890464 R trehalose-6-phosphate synthase complement(1889040..1890464) Escherichia coli 536 4189540 YP_669741.1 CDS ECP_1839 NC_008253.1 1890439 1891296 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(1890439..1891296) Escherichia coli 536 4189541 YP_669742.1 CDS araH NC_008253.1 1891406 1892392 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(1891406..1892392) Escherichia coli 536 4189542 YP_669743.1 CDS araG NC_008253.1 1892407 1893921 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(1892407..1893921) Escherichia coli 536 4189543 YP_669744.1 CDS ECP_1842 NC_008253.1 1893991 1894980 R L-arabinose-binding periplasmic protein complement(1893991..1894980) Escherichia coli 536 4189544 YP_669745.1 CDS ECP_1843 NC_008253.1 1895066 1895305 R hypothetical protein complement(1895066..1895305) Escherichia coli 536 4189545 YP_669746.1 CDS ECP_1844 NC_008253.1 1895777 1896280 D ferritin 1895777..1896280 Escherichia coli 536 4189546 YP_669747.1 CDS ECP_1845 NC_008253.1 1896359 1896610 R hypothetical protein complement(1896359..1896610) Escherichia coli 536 4189547 YP_669748.1 CDS ECP_1846 NC_008253.1 1896722 1896868 D hypothetical protein 1896722..1896868 Escherichia coli 536 4191112 YP_669749.1 CDS ECP_1847 NC_008253.1 1897074 1897397 D hypothetical protein 1897074..1897397 Escherichia coli 536 4191113 YP_669750.1 CDS ECP_1848 NC_008253.1 1897569 1898066 D cytoplasmic iron storage protein; ferritin 1897569..1898066 Escherichia coli 536 4191114 YP_669751.1 CDS ECP_1849 NC_008253.1 1898104 1898343 R hypothetical protein complement(1898104..1898343) Escherichia coli 536 4191115 YP_669752.1 CDS ECP_1850 NC_008253.1 1898534 1899745 D tyrosine-specific transport protein 1898534..1899745 Escherichia coli 536 4191116 YP_669753.1 CDS ECP_1851 NC_008253.1 1899807 1900472 R metal-binding protein related to the C-terminal domain of SecA; hypothetical protein complement(1899807..1900472) Escherichia coli 536 4191117 YP_669754.1 CDS ECP_1852 NC_008253.1 1901121 1901669 R phosphatidylglycerophosphate synthetase complement(1901121..1901669) Escherichia coli 536 4191118 YP_669755.1 CDS ECP_1853 NC_008253.1 1901726 1903051 R UvrABC system protein C; UvrC excinuclease ABC subunit C complement(1901726..1903051) Escherichia coli 536 4191119 YP_669756.1 CDS ECP_1854 NC_008253.1 1903139 1903690 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(1903139..1903690) Escherichia coli 536 4191120 YP_669757.1 CDS fliA NC_008253.1 1903736 1904455 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(1903736..1904455) Escherichia coli 536 4191121 YP_669758.1 CDS ECP_1856 NC_008253.1 1904526 1904732 R hypothetical protein complement(1904526..1904732) Escherichia coli 536 4191122 YP_669759.1 CDS ECP_1857 NC_008253.1 1904774 1906441 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(1904774..1906441) Escherichia coli 536 4191123 YP_669760.1 CDS fliD NC_008253.1 1906707 1908113 D involved in flagellin assembly; flagellar capping protein 1906707..1908113 Escherichia coli 536 4191124 YP_669761.1 CDS fliS NC_008253.1 1908138 1908548 D flagellin specific chaperone; flagellar protein FliS 1908138..1908548 Escherichia coli 536 4191125 YP_669762.1 CDS ECP_1860 NC_008253.1 1908548 1908913 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 1908548..1908913 Escherichia coli 536 4191126 YP_669763.1 CDS ECP_1861 NC_008253.1 1908991 1910478 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1908991..1910478 Escherichia coli 536 4191127 YP_669764.1 CDS ECP_1862 NC_008253.1 1910512 1910925 R hypothetical protein complement(1910512..1910925) Escherichia coli 536 4191128 YP_669765.1 CDS ECP_1863 NC_008253.1 1911112 1912317 D inner membrane protein 1911112..1912317 Escherichia coli 536 4191129 YP_669766.1 CDS ECP_1864 NC_008253.1 1912314 1912547 D hypothetical protein 1912314..1912547 Escherichia coli 536 4191130 YP_669767.1 CDS ECP_1865 NC_008253.1 1912656 1913324 D hypothetical protein 1912656..1913324 Escherichia coli 536 4190368 YP_669768.1 CDS ECP_1866 NC_008253.1 1913321 1913506 D hypothetical protein 1913321..1913506 Escherichia coli 536 4190369 YP_669769.1 CDS ECP_1867 NC_008253.1 1913838 1914920 D outer membrane porin protein LC 1913838..1914920 Escherichia coli 536 4190370 YP_669770.1 CDS ECP_1868 NC_008253.1 1915422 1916174 R transcriptional regulator YbcM complement(1915422..1916174) Escherichia coli 536 4190371 YP_669771.1 CDS ECP_1869 NC_008253.1 1916229 1916780 R DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor complement(1916229..1916780) Escherichia coli 536 4190372 YP_669772.1 CDS emrE NC_008253.1 1916949 1917446 R ethidium resistance protein; member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein complement(1916949..1917446) Escherichia coli 536 4190373 YP_669773.1 CDS fliE NC_008253.1 1917626 1917940 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1917626..1917940) Escherichia coli 536 4190374 YP_669774.1 CDS fliF NC_008253.1 1918155 1919813 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1918155..1919813 Escherichia coli 536 4190375 YP_669775.1 CDS fliG NC_008253.1 1919806 1920801 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1919806..1920801 Escherichia coli 536 4190376 YP_669776.1 CDS fliH NC_008253.1 1920794 1921480 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1920794..1921480 Escherichia coli 536 4190377 YP_669777.1 CDS fliI NC_008253.1 1921480 1922853 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1921480..1922853 Escherichia coli 536 4190378 YP_669778.1 CDS fliJ NC_008253.1 1922872 1923315 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 1922872..1923315 Escherichia coli 536 4190379 YP_669779.1 CDS ECP_1877 NC_008253.1 1923312 1924439 D flagellar hook-length control protein 1923312..1924439 Escherichia coli 536 4190380 YP_669780.1 CDS fliL NC_008253.1 1924544 1925008 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 1924544..1925008 Escherichia coli 536 4190381 YP_669781.1 CDS fliM NC_008253.1 1924968 1926017 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1924968..1926017 Escherichia coli 536 4190382 YP_669782.1 CDS fliN NC_008253.1 1926014 1926427 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1926014..1926427 Escherichia coli 536 4190383 YP_669783.1 CDS ECP_1881 NC_008253.1 1926430 1926795 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 1926430..1926795 Escherichia coli 536 4190384 YP_669784.1 CDS fliP NC_008253.1 1926795 1927532 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1926795..1927532 Escherichia coli 536 4190385 YP_669785.1 CDS fliQ NC_008253.1 1927542 1927811 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1927542..1927811 Escherichia coli 536 4190386 YP_669786.1 CDS fliR NC_008253.1 1927820 1928605 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1927820..1928605 Escherichia coli 536 4190387 YP_669787.1 CDS ECP_1885 NC_008253.1 1928895 1929518 D colanic acid capsular biosynthesis activation protein A 1928895..1929518 Escherichia coli 536 4187245 YP_669788.1 CDS ECP_1886 NC_008253.1 1929562 1929750 R hypothetical protein complement(1929562..1929750) Escherichia coli 536 4187246 YP_669789.1 CDS ECP_1887 NC_008253.1 1929911 1930141 D hypothetical protein 1929911..1930141 Escherichia coli 536 4187247 YP_669790.1 CDS ECP_1888 NC_008253.1 1930437 1931252 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1930437..1931252 Escherichia coli 536 4187248 YP_669791.1 CDS ECP_1889 NC_008253.1 1931249 1932943 R hypothetical protein complement(1931249..1932943) Escherichia coli 536 4187249 YP_669792.1 CDS ECP_1890 NC_008253.1 1933114 1933296 R hypothetical protein complement(1933114..1933296) Escherichia coli 536 4187250 YP_669793.1 CDS ECP_1891 NC_008253.1 1933375 1934292 R hypothetical protein complement(1933375..1934292) Escherichia coli 536 4187251 YP_669794.1 CDS ECP_1892 NC_008253.1 1934465 1935385 D hypothetical protein 1934465..1935385 Escherichia coli 536 4187252 YP_669795.1 CDS ECP_1893 NC_008253.1 1935374 1935844 R very short patch repair protein complement(1935374..1935844) Escherichia coli 536 4187253 YP_669796.1 CDS ECP_1894 NC_008253.1 1935825 1937243 R DNA cytosine methylase complement(1935825..1937243) Escherichia coli 536 4187254 YP_669797.1 CDS ECP_1895 NC_008253.1 1937310 1938005 R hypothetical protein complement(1937310..1938005) Escherichia coli 536 4187255 YP_669798.1 CDS ECP_1896 NC_008253.1 1938045 1938347 R hypothetical protein complement(1938045..1938347) Escherichia coli 536 4187256 YP_669799.1 CDS ECP_1897 NC_008253.1 1938503 1938688 D hypothetical protein 1938503..1938688 Escherichia coli 536 4187257 YP_669800.1 CDS ECP_1898 NC_008253.1 1938975 1940033 D outer membrane pore protein 1938975..1940033 Escherichia coli 536 4187258 YP_669801.1 CDS ECP_1899 NC_008253.1 1940115 1940249 D hypothetical protein 1940115..1940249 Escherichia coli 536 4187259 YP_669802.1 CDS ECP_1900 NC_008253.1 1940629 1941480 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 1940629..1941480 Escherichia coli 536 4187260 YP_669803.1 CDS ECP_1901 NC_008253.1 1941588 1942946 R sensor-like histidine kinase YedV complement(1941588..1942946) Escherichia coli 536 4187261 YP_669804.1 CDS ECP_1902 NC_008253.1 1942946 1943728 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(1942946..1943728) Escherichia coli 536 4187262 YP_669805.1 CDS ECP_1903 NC_008253.1 1943750 1944163 D transthyretin-like protein 1943750..1944163 Escherichia coli 536 4187263 YP_669806.1 CDS ECP_1904 NC_008253.1 1944272 1944505 D hypothetical protein 1944272..1944505 Escherichia coli 536 4188224 YP_669807.1 CDS ECP_1905 NC_008253.1 1944640 1945275 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 1944640..1945275 Escherichia coli 536 4188225 YP_669808.1 CDS ECP_1906 NC_008253.1 1945276 1945911 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 1945276..1945911 Escherichia coli 536 4188226 YP_669809.1 CDS ECP_1907 NC_008253.1 1946169 1946819 D hypothetical protein 1946169..1946819 Escherichia coli 536 4188227 YP_669810.1 CDS ECP_1908 NC_008253.1 1946855 1947184 D hypothetical protein 1946855..1947184 Escherichia coli 536 4188228 YP_669811.1 CDS ECP_1909 NC_008253.1 1947667 1948887 D phage-related integrase 1947667..1948887 Escherichia coli 536 4188229 YP_669812.1 CDS ECP_1910 NC_008253.1 1949001 1950821 D hypothetical protein 1949001..1950821 Escherichia coli 536 4188230 YP_669813.1 CDS ECP_1911 NC_008253.1 1950936 1952399 R PilV-like protein complement(1950936..1952399) Escherichia coli 536 4188231 YP_669814.1 CDS ECP_1912 NC_008253.1 1952452 1953009 R type IV pilin protein complement(1952452..1953009) Escherichia coli 536 4188232 YP_669815.1 CDS ECP_1913 NC_008253.1 1953408 1953713 R hypothetical protein complement(1953408..1953713) Escherichia coli 536 4188233 YP_669816.1 CDS ECP_1914 NC_008253.1 1954359 1955861 D hypothetical protein 1954359..1955861 Escherichia coli 536 4188234 YP_669817.1 CDS ECP_1915 NC_008253.1 1955978 1956841 D hypothetical protein 1955978..1956841 Escherichia coli 536 4188235 YP_669818.1 CDS ECP_1916 NC_008253.1 1957136 1957369 D hypothetical protein 1957136..1957369 Escherichia coli 536 4188236 YP_669819.1 CDS ECP_1917 NC_008253.1 1957619 1958455 D hypothetical protein 1957619..1958455 Escherichia coli 536 4188237 YP_669820.1 CDS ECP_1918 NC_008253.1 1958515 1958790 R hypothetical protein complement(1958515..1958790) Escherichia coli 536 4188238 YP_669821.1 CDS ECP_1919 NC_008253.1 1958801 1959331 R hypothetical protein complement(1958801..1959331) Escherichia coli 536 4188239 YP_669822.1 CDS ECP_1920 NC_008253.1 1959764 1960237 D hypothetical protein 1959764..1960237 Escherichia coli 536 4188240 YP_669823.1 CDS ECP_1921 NC_008253.1 1960269 1960439 D hypothetical protein 1960269..1960439 Escherichia coli 536 4188241 YP_669824.1 CDS ECP_1922 NC_008253.1 1960727 1961899 R hypothetical protein complement(1960727..1961899) Escherichia coli 536 4188242 YP_669825.1 CDS ECP_1923 NC_008253.1 1961960 1962922 R hypothetical protein complement(1961960..1962922) Escherichia coli 536 4188243 YP_669826.1 CDS ECP_1924 NC_008253.1 1964276 1964857 D hypothetical protein 1964276..1964857 Escherichia coli 536 4187452 YP_669827.1 CDS ECP_1925 NC_008253.1 1964942 1965673 R hypothetical protein complement(1964942..1965673) Escherichia coli 536 4187453 YP_669828.1 CDS ECP_1926 NC_008253.1 1965847 1966326 D hypothetical protein 1965847..1966326 Escherichia coli 536 4187454 YP_669829.1 CDS ECP_1927 NC_008253.1 1966487 1966891 D DNA-binding protein 1966487..1966891 Escherichia coli 536 4187455 YP_669830.1 CDS ECP_1928 NC_008253.1 1966955 1967305 R hypothetical protein complement(1966955..1967305) Escherichia coli 536 4187456 YP_669831.1 CDS ECP_1929 NC_008253.1 1967414 1967656 R hypothetical protein complement(1967414..1967656) Escherichia coli 536 4187457 YP_669832.1 CDS ECP_1930 NC_008253.1 1967729 1968025 R hypothetical protein complement(1967729..1968025) Escherichia coli 536 4187458 YP_669833.1 CDS ECP_1931 NC_008253.1 1968078 1968368 R hypothetical protein complement(1968078..1968368) Escherichia coli 536 4187459 YP_669834.1 CDS ECP_1932 NC_008253.1 1968450 1968668 R regulatory protein complement(1968450..1968668) Escherichia coli 536 4187460 YP_669835.1 CDS ECP_1933 NC_008253.1 1968885 1969721 R hypothetical protein complement(1968885..1969721) Escherichia coli 536 4187461 YP_669836.1 CDS ECP_1934 NC_008253.1 1970183 1970980 D hypothetical protein 1970183..1970980 Escherichia coli 536 4187462 YP_669837.1 CDS ECP_1936 NC_008253.1 1971537 1972580 D P4-like integrase 1971537..1972580 Escherichia coli 536 4187464 YP_669838.1 CDS ECP_1937 NC_008253.1 1972774 1974078 R catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 complement(1972774..1974078) Escherichia coli 536 4187465 YP_669839.1 CDS ECP_1938 NC_008253.1 1974106 1975494 R YbtX; cytoplasmic transmembrane protein complement(1974106..1975494) Escherichia coli 536 4187466 YP_669840.1 CDS ECP_1939 NC_008253.1 1975379 1977181 R ABC transporter permease complement(1975379..1977181) Escherichia coli 536 4187467 YP_669841.1 CDS ECP_1940 NC_008253.1 1977168 1978880 R inner membrane ABC-transporter (YbtP) complement(1977168..1978880) Escherichia coli 536 4187468 YP_669842.1 CDS ECP_1941 NC_008253.1 1979137 1980096 D yersiniabactin transcriptional regulator, YbtA 1979137..1980096 Escherichia coli 536 4187469 YP_669843.1 CDS ECP_1942 NC_008253.1 1980287 1986394 D HMWP2 nonribosomal peptidesynthetase; yersiniabactin biosynthetic protein 1980287..1986394 Escherichia coli 536 4191228 YP_669844.1 CDS ECP_1943 NC_008253.1 1986482 1995973 D HMWP1nonribosomal peptide/polyketide synthase; yersiniabactin biosynthetic protein 1986482..1995973 Escherichia coli 536 4191229 YP_669845.1 CDS ECP_1944 NC_008253.1 1995970 1997070 D yersiniabactin biosynthetic protein YbtU 1995970..1997070 Escherichia coli 536 4191230 YP_669846.1 CDS ECP_1945 NC_008253.1 1997082 1997870 D yersiniabactin biosynthetic protein YbtT 1997082..1997870 Escherichia coli 536 4191231 YP_669847.1 CDS ECP_1946 NC_008253.1 1997874 1999451 D yersiniabactin siderophore biosynthetic protein YbtE 1997874..1999451 Escherichia coli 536 4191232 YP_669848.1 CDS ECP_1947 NC_008253.1 1999582 2001603 D pesticin receptor 1999582..2001603 Escherichia coli 536 4191233 YP_669849.1 CDS ECP_1948 NC_008253.1 2002251 2003000 D hypothetical protein 2002251..2003000 Escherichia coli 536 4191234 YP_669850.1 CDS ECP_1949 NC_008253.1 2002927 2003097 D hypothetical protein 2002927..2003097 Escherichia coli 536 4191235 YP_669851.1 CDS ECP_1950 NC_008253.1 2003133 2004602 D hypothetical protein 2003133..2004602 Escherichia coli 536 4191236 YP_669852.1 CDS ECP_1951 NC_008253.1 2004615 2005091 D hypothetical protein 2004615..2005091 Escherichia coli 536 4191237 YP_669853.1 CDS ECP_1952 NC_008253.1 2005219 2006271 R hypothetical protein complement(2005219..2006271) Escherichia coli 536 4191238 YP_669854.1 CDS ECP_1953 NC_008253.1 2006300 2006458 D hypothetical protein 2006300..2006458 Escherichia coli 536 4191239 YP_669855.1 CDS ECP_1954 NC_008253.1 2006586 2007902 D shikimate transporter 2006586..2007902 Escherichia coli 536 4191240 YP_669856.1 CDS ECP_1955 NC_008253.1 2008004 2009458 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2008004..2009458 Escherichia coli 536 4191241 YP_669857.1 CDS ECP_1956 NC_008253.1 2009801 2010517 D hypothetical protein 2009801..2010517 Escherichia coli 536 4191242 YP_669858.1 CDS ECP_1957 NC_008253.1 2010573 2010860 R hypothetical protein complement(2010573..2010860) Escherichia coli 536 4191243 YP_669859.1 CDS ECP_1958 NC_008253.1 2011373 2012290 D Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2011373..2012290 Escherichia coli 536 4191244 YP_669860.1 CDS cbl NC_008253.1 2012392 2013342 D LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2012392..2013342 Escherichia coli 536 4191245 YP_669861.1 CDS ECP_1960 NC_008253.1 2013616 2015103 D hypothetical protein 2013616..2015103 Escherichia coli 536 4191246 YP_669862.1 CDS ECP_1962 NC_008253.1 2015441 2016712 D bacteriophage integrase 2015441..2016712 Escherichia coli 536 4191574 YP_669863.1 CDS ECP_1963 NC_008253.1 2016992 2017504 R hypothetical protein complement(2016992..2017504) Escherichia coli 536 4191575 YP_669864.1 CDS ECP_1964 NC_008253.1 2017539 2018261 R thioesterase complement(2017539..2018261) Escherichia coli 536 4191576 YP_669865.1 CDS ECP_1965 NC_008253.1 2018254 2019768 R hypothetical protein complement(2018254..2019768) Escherichia coli 536 4191577 YP_669866.1 CDS ECP_1966 NC_008253.1 2019781 2022240 R polyketide synthase complement(2019781..2022240) Escherichia coli 536 4191578 YP_669867.1 CDS ECP_1967 NC_008253.1 2022271 2026638 R non-ribosomal peptide synthetase complement(2022271..2026638) Escherichia coli 536 4191579 YP_669868.1 CDS ECP_1968 NC_008253.1 2026635 2028074 R drug/sodium antiporter complement(2026635..2028074) Escherichia coli 536 4191580 YP_669869.1 CDS ECP_1969 NC_008253.1 2028136 2029599 R amidase complement(2028136..2029599) Escherichia coli 536 4191581 YP_669870.1 CDS ECP_1970 NC_008253.1 2029592 2036056 R non-ribosomal peptide synthase complement(2029592..2036056) Escherichia coli 536 4191582 YP_669871.1 CDS ECP_1971 NC_008253.1 2036067 2042567 R non-ribosomal peptide synthase complement(2036067..2042567) Escherichia coli 536 4191583 YP_669872.1 CDS ECP_1972 NC_008253.1 2042611 2045643 R polyketide synthase complement(2042611..2045643) Escherichia coli 536 4191584 YP_669873.1 CDS ECP_1973 NC_008253.1 2045693 2050489 R peptide synthetase complement(2045693..2050489) Escherichia coli 536 4191585 YP_669874.1 CDS ECP_1974 NC_008253.1 2050537 2051805 R malonyl-CoA transacylase complement(2050537..2051805) Escherichia coli 536 4191586 YP_669875.1 CDS ECP_1975 NC_008253.1 2051802 2052932 R acyl-CoA dehydrogenase complement(2051802..2052932) Escherichia coli 536 4191587 YP_669876.1 CDS ECP_1976 NC_008253.1 2052936 2053184 R D-alanyl carrier protein complement(2052936..2053184) Escherichia coli 536 4191588 YP_669877.1 CDS ECP_1977 NC_008253.1 2053214 2054083 R 3-hydroxybutyryl-CoA dehydrogenase complement(2053214..2054083) Escherichia coli 536 4191589 YP_669878.1 CDS ECP_1978 NC_008253.1 2054093 2056693 R polyketide synthase complement(2054093..2056693) Escherichia coli 536 4191590 YP_669879.1 CDS ECP_1979 NC_008253.1 2056734 2066354 R polyketide synthase complement(2056734..2066354) Escherichia coli 536 4191591 YP_669880.1 CDS ECP_1980 NC_008253.1 2066393 2066581 D hypothetical protein 2066393..2066581 Escherichia coli 536 4188002 YP_669881.1 CDS ECP_1981 NC_008253.1 2066788 2067000 D transcriptional regulator 2066788..2067000 Escherichia coli 536 4188003 YP_669882.1 CDS ECP_1982 NC_008253.1 2067001 2067735 D 4'-phosphopantetheinyl transferase 2067001..2067735 Escherichia coli 536 4188004 YP_669883.1 CDS ECP_1983 NC_008253.1 2067881 2068147 D IS1400 transposase A 2067881..2068147 Escherichia coli 536 4188005 YP_669884.1 CDS ECP_1984 NC_008253.1 2068252 2068731 D IS1400 transposase B 2068252..2068731 Escherichia coli 536 4188006 YP_669885.1 CDS ECP_1985 NC_008253.1 2068722 2068949 D transposase 2068722..2068949 Escherichia coli 536 4188007 YP_669886.1 CDS ECP_1986 NC_008253.1 2069039 2069452 R hypothetical protein complement(2069039..2069452) Escherichia coli 536 4188008 YP_669887.1 CDS ECP_1987 NC_008253.1 2069480 2069707 R hypothetical protein complement(2069480..2069707) Escherichia coli 536 4188009 YP_669888.1 CDS ECP_1988 NC_008253.1 2069756 2070691 R hypothetical protein complement(2069756..2070691) Escherichia coli 536 4188010 YP_669889.1 CDS cobT NC_008253.1 2070753 2071832 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2070753..2071832) Escherichia coli 536 4188011 YP_669890.1 CDS cobS NC_008253.1 2071844 2072587 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2071844..2072587) Escherichia coli 536 4188012 YP_669891.1 CDS cobU NC_008253.1 2072584 2073129 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(2072584..2073129) Escherichia coli 536 4188013 YP_669892.1 CDS ECP_1992 NC_008253.1 2073594 2073758 R hypothetical protein complement(2073594..2073758) Escherichia coli 536 4188014 YP_669893.1 CDS ECP_1993 NC_008253.1 2074497 2074694 D hypothetical protein 2074497..2074694 Escherichia coli 536 4188015 YP_669894.1 CDS ECP_1994 NC_008253.1 2074801 2076948 D outer membrane receptor for iron compound or colicin 2074801..2076948 Escherichia coli 536 4188016 YP_669895.1 CDS ECP_1995 NC_008253.1 2076923 2077207 R hypothetical protein complement(2076923..2077207) Escherichia coli 536 4188017 YP_669896.1 CDS ECP_1996 NC_008253.1 2077319 2077963 R hypothetical protein complement(2077319..2077963) Escherichia coli 536 4188018 YP_669897.1 CDS ECP_1997 NC_008253.1 2077948 2079171 R phosphoadenosine phosphosulfate reductase complement(2077948..2079171) Escherichia coli 536 4188019 YP_669898.1 CDS ECP_1998 NC_008253.1 2080219 2080872 D hypothetical protein 2080219..2080872 Escherichia coli 536 4188020 YP_669899.1 CDS ECP_1999 NC_008253.1 2080886 2082082 D hypothetical protein 2080886..2082082 Escherichia coli 536 4188021 YP_669900.1 CDS ECP_2000 NC_008253.1 2081949 2082641 D hypothetical protein 2081949..2082641 Escherichia coli 536 4190388 YP_669901.1 CDS ECP_2001 NC_008253.1 2082643 2083416 D hypothetical protein 2082643..2083416 Escherichia coli 536 4190389 YP_669902.1 CDS ECP_2002 NC_008253.1 2083687 2084166 D hypothetical protein 2083687..2084166 Escherichia coli 536 4190390 YP_669903.1 CDS ECP_2003 NC_008253.1 2084106 2084222 D hypothetical protein 2084106..2084222 Escherichia coli 536 4190391 YP_669904.1 CDS ECP_2004 NC_008253.1 2084418 2085632 D carbohydrate kinase 2084418..2085632 Escherichia coli 536 4190392 YP_669905.1 CDS ECP_2005 NC_008253.1 2085646 2086404 D hypothetical protein 2085646..2086404 Escherichia coli 536 4190393 YP_669906.1 CDS ECP_2006 NC_008253.1 2086458 2087423 D hypothetical protein 2086458..2087423 Escherichia coli 536 4190394 YP_669907.1 CDS ECP_2007 NC_008253.1 2087426 2088460 D phosphotriesterase 2087426..2088460 Escherichia coli 536 4190395 YP_669908.1 CDS ECP_2008 NC_008253.1 2088500 2088613 R hypothetical protein complement(2088500..2088613) Escherichia coli 536 4190396 YP_669909.1 CDS ECP_2009 NC_008253.1 2088676 2088762 R hypothetical protein complement(2088676..2088762) Escherichia coli 536 4190397 YP_669910.1 CDS ECP_2010 NC_008253.1 2088872 2089033 R transposase (part) complement(2088872..2089033) Escherichia coli 536 4190398 YP_669911.1 CDS ECP_2011 NC_008253.1 2089112 2089969 R transposase complement(2089112..2089969) Escherichia coli 536 4190399 YP_669912.1 CDS ECP_2012 NC_008253.1 2090228 2090491 R transposase complement(2090228..2090491) Escherichia coli 536 4190400 YP_669913.1 CDS ECP_2013 NC_008253.1 2090775 2091014 R hypothetical protein complement(2090775..2091014) Escherichia coli 536 4190401 YP_669914.1 CDS ECP_2014 NC_008253.1 2091160 2091561 R hypothetical protein complement(2091160..2091561) Escherichia coli 536 4190402 YP_669915.1 CDS ECP_2015 NC_008253.1 2091727 2092185 R hypothetical protein complement(2091727..2092185) Escherichia coli 536 4190403 YP_669916.1 CDS ECP_2016 NC_008253.1 2092100 2092297 R hypothetical protein complement(2092100..2092297) Escherichia coli 536 4190404 YP_669917.1 CDS ECP_2017 NC_008253.1 2093064 2093444 D hypothetical protein 2093064..2093444 Escherichia coli 536 4190405 YP_669918.1 CDS ECP_2018 NC_008253.1 2093412 2093645 R hypothetical protein complement(2093412..2093645) Escherichia coli 536 4190406 YP_669919.1 CDS ECP_2019 NC_008253.1 2093877 2095073 D transposase 2093877..2095073 Escherichia coli 536 4190081 YP_669920.1 CDS ECP_2020 NC_008253.1 2095269 2095475 D regulatory protein 2095269..2095475 Escherichia coli 536 4190082 YP_669921.1 CDS ECP_2021 NC_008253.1 2095569 2096171 D hypothetical protein 2095569..2096171 Escherichia coli 536 4190083 YP_669922.1 CDS ECP_2022 NC_008253.1 2096645 2096860 D hypothetical protein 2096645..2096860 Escherichia coli 536 4190084 YP_669923.1 CDS ECP_2023 NC_008253.1 2096951 2097181 R hypothetical protein complement(2096951..2097181) Escherichia coli 536 4190085 YP_669924.1 CDS ECP_2024 NC_008253.1 2097197 2097976 R transposase/IS protein complement(2097197..2097976) Escherichia coli 536 4190086 YP_669925.1 CDS ECP_2025 NC_008253.1 2097976 2098998 R transposase for insertion sequence IS100 complement(2097976..2098998) Escherichia coli 536 4190087 YP_669926.1 CDS ECP_2026 NC_008253.1 2099025 2099267 R hypothetical protein complement(2099025..2099267) Escherichia coli 536 4190088 YP_669927.1 CDS ECP_2027 NC_008253.1 2099300 2099527 R hypothetical protein complement(2099300..2099527) Escherichia coli 536 4190089 YP_669928.1 CDS ECP_2028 NC_008253.1 2099549 2099926 R hypothetical protein complement(2099549..2099926) Escherichia coli 536 4190090 YP_669929.1 CDS ECP_2029 NC_008253.1 2099853 2100113 D hypothetical protein 2099853..2100113 Escherichia coli 536 4190091 YP_669930.1 CDS ECP_2030 NC_008253.1 2100495 2101280 D hypothetical protein 2100495..2101280 Escherichia coli 536 4190092 YP_669931.1 CDS ECP_2031 NC_008253.1 2101205 2101666 D hypothetical protein 2101205..2101666 Escherichia coli 536 4190093 YP_669932.1 CDS ECP_2032 NC_008253.1 2101731 2101967 D hypothetical protein 2101731..2101967 Escherichia coli 536 4190094 YP_669933.1 CDS ECP_2033 NC_008253.1 2102508 2103275 R ABC transporter complement(2102508..2103275) Escherichia coli 536 4190095 YP_669934.1 CDS ECP_2034 NC_008253.1 2103272 2104330 R iron ABC transporter complement(2103272..2104330) Escherichia coli 536 4190096 YP_669935.1 CDS ECP_2035 NC_008253.1 2104349 2105341 R iron-chelating periplasmic-binding protein complement(2104349..2105341) Escherichia coli 536 4190097 YP_669936.1 CDS ECP_2036 NC_008253.1 2105349 2107514 R TonB-dependent receptor complement(2105349..2107514) Escherichia coli 536 4190098 YP_669937.1 CDS ECP_2037 NC_008253.1 2107943 2108377 D hypothetical protein 2107943..2108377 Escherichia coli 536 4190099 YP_669938.1 CDS ECP_2038 NC_008253.1 2108595 2110979 D hypothetical protein 2108595..2110979 Escherichia coli 536 4190100 YP_669939.1 CDS ECP_2039 NC_008253.1 2110976 2111881 D hypothetical protein 2110976..2111881 Escherichia coli 536 4189792 YP_669940.1 CDS ECP_2040 NC_008253.1 2111878 2112948 D hypothetical protein 2111878..2112948 Escherichia coli 536 4189793 YP_669941.1 CDS ECP_2041 NC_008253.1 2113084 2113761 D hypothetical protein 2113084..2113761 Escherichia coli 536 4189794 YP_669942.1 CDS ECP_2042 NC_008253.1 2113777 2114187 D hypothetical protein 2113777..2114187 Escherichia coli 536 4189795 YP_669943.1 CDS ECP_2043 NC_008253.1 2114408 2115229 D hypothetical protein 2114408..2115229 Escherichia coli 536 4189796 YP_669944.1 CDS ECP_2044 NC_008253.1 2115492 2115965 D antirestriction protein 2115492..2115965 Escherichia coli 536 4189797 YP_669945.1 CDS ECP_2045 NC_008253.1 2115981 2116457 D radC-like protein YeeS 2115981..2116457 Escherichia coli 536 4189798 YP_669946.1 CDS ECP_2046 NC_008253.1 2116526 2116747 D hypothetical protein 2116526..2116747 Escherichia coli 536 4189799 YP_669947.1 CDS ECP_2047 NC_008253.1 2116821 2117189 D hypothetical protein 2116821..2117189 Escherichia coli 536 4189800 YP_669948.1 CDS ECP_2048 NC_008253.1 2117278 2117652 D hypothetical protein 2117278..2117652 Escherichia coli 536 4189801 YP_669949.1 CDS ECP_2049 NC_008253.1 2117649 2117843 D hypothetical protein 2117649..2117843 Escherichia coli 536 4189802 YP_669950.1 CDS ECP_2050 NC_008253.1 2118284 2118640 D hypothetical protein 2118284..2118640 Escherichia coli 536 4189803 YP_669951.1 CDS ECP_2051 NC_008253.1 2118741 2119070 R hypothetical protein complement(2118741..2119070) Escherichia coli 536 4189804 YP_669952.1 CDS ECP_2052 NC_008253.1 2119242 2120300 R hypothetical protein complement(2119242..2120300) Escherichia coli 536 4189805 YP_669953.1 CDS ECP_2053 NC_008253.1 2120498 2120971 R DNA gyrase inhibitor complement(2120498..2120971) Escherichia coli 536 4189806 YP_669954.1 CDS dacD NC_008253.1 2121090 2122256 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2121090..2122256) Escherichia coli 536 4189807 YP_669955.1 CDS sbcB NC_008253.1 2122465 2123892 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2122465..2123892 Escherichia coli 536 4189808 YP_669956.1 CDS ECP_2056 NC_008253.1 2123966 2124421 R similar to C-terminal part of amino acid permease YeeF; hypothetical protein complement(2123966..2124421) Escherichia coli 536 4189809 YP_669957.1 CDS ECP_2057 NC_008253.1 2124477 2125328 R similar to N-terminal part of amino acid permease YeeF; hypothetical protein complement(2124477..2125328) Escherichia coli 536 4189810 YP_669958.1 CDS ECP_2058 NC_008253.1 2125595 2126524 R LysR family transcriptional regulator complement(2125595..2126524) Escherichia coli 536 4191287 YP_669959.1 CDS ECP_2059 NC_008253.1 2126570 2127394 R protein YeeZ complement(2126570..2127394) Escherichia coli 536 4191288 YP_669960.1 CDS ECP_2060 NC_008253.1 2127477 2127731 R hypothetical protein complement(2127477..2127731) Escherichia coli 536 4191289 YP_669961.1 CDS ECP_2061 NC_008253.1 2127728 2127979 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2127728..2127979) Escherichia coli 536 4191290 YP_669962.1 CDS hisG NC_008253.1 2128458 2129357 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2128458..2129357 Escherichia coli 536 4191291 YP_669963.1 CDS hisD NC_008253.1 2129363 2130667 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2129363..2130667 Escherichia coli 536 4191292 YP_669964.1 CDS ECP_2064 NC_008253.1 2130664 2131734 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2130664..2131734 Escherichia coli 536 4191293 YP_669965.1 CDS ECP_2065 NC_008253.1 2131734 2132801 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2131734..2132801 Escherichia coli 536 4191294 YP_669966.1 CDS hisH NC_008253.1 2132801 2133391 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2132801..2133391 Escherichia coli 536 4191295 YP_669967.1 CDS ECP_2067 NC_008253.1 2133391 2134128 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2133391..2134128 Escherichia coli 536 4191296 YP_669968.1 CDS ECP_2068 NC_008253.1 2134110 2134886 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2134110..2134886 Escherichia coli 536 4191297 YP_669969.1 CDS ECP_2069 NC_008253.1 2134880 2135491 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2134880..2135491 Escherichia coli 536 4191298 YP_669970.1 CDS ECP_2070 NC_008253.1 2135677 2136654 R chain length determinant protein complement(2135677..2136654) Escherichia coli 536 4191299 YP_669971.1 CDS ECP_2071 NC_008253.1 2136797 2137963 R UDP-glucose 6-dehydrogenase complement(2136797..2137963) Escherichia coli 536 4191300 YP_669972.1 CDS ECP_2072 NC_008253.1 2138213 2139619 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2138213..2139619) Escherichia coli 536 4191301 YP_669973.1 CDS ECP_2073 NC_008253.1 2139782 2141152 R phosphomannomutase complement(2139782..2141152) Escherichia coli 536 4191302 YP_669974.1 CDS ECP_2074 NC_008253.1 2141235 2142686 R mannose-1-phosphate guanylyltransferase complement(2141235..2142686) Escherichia coli 536 4191303 YP_669975.1 CDS ECP_2075 NC_008253.1 2142664 2143869 R glycosyltransferase complement(2142664..2143869) Escherichia coli 536 4191304 YP_669976.1 CDS ECP_2076 NC_008253.1 2143890 2144897 R UDP-glucose 4-epimerase complement(2143890..2144897) Escherichia coli 536 4191305 YP_669977.1 CDS ECP_2077 NC_008253.1 2144914 2146059 R glycosyltransferase complement(2144914..2146059) Escherichia coli 536 4191306 YP_669978.1 CDS ECP_2078 NC_008253.1 2146046 2147077 R glycosyltransferase complement(2146046..2147077) Escherichia coli 536 4188806 YP_669979.1 CDS ECP_2079 NC_008253.1 2147074 2147934 R glycosyltransferase complement(2147074..2147934) Escherichia coli 536 4188807 YP_669980.1 CDS ECP_2080 NC_008253.1 2147940 2149283 R antigen polymerase complement(2147940..2149283) Escherichia coli 536 4188808 YP_669981.1 CDS ECP_2081 NC_008253.1 2149283 2150521 R O antigen flippase complement(2149283..2150521) Escherichia coli 536 4188809 YP_669982.1 CDS ECP_2082 NC_008253.1 2150896 2151789 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase complement(2150896..2151789) Escherichia coli 536 4188810 YP_669983.1 CDS wcaM NC_008253.1 2151964 2153358 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2151964..2153358) Escherichia coli 536 4188811 YP_669984.1 CDS ECP_2084 NC_008253.1 2153369 2154589 R colanic acid biosynthesis glycosyl transferase WcaL complement(2153369..2154589) Escherichia coli 536 4188812 YP_669985.1 CDS ECP_2085 NC_008253.1 2154586 2155866 R pyruvyl transferase complement(2154586..2155866) Escherichia coli 536 4188813 YP_669986.1 CDS ECP_2086 NC_008253.1 2156432 2157910 R colanic acid exporter complement(2156432..2157910) Escherichia coli 536 4188814 YP_669987.1 CDS ECP_2087 NC_008253.1 2157912 2159306 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2157912..2159306) Escherichia coli 536 4188815 YP_669988.1 CDS ECP_2088 NC_008253.1 2159361 2160731 R phosphomannomutase complement(2159361..2160731) Escherichia coli 536 4188816 YP_669989.1 CDS ECP_2089 NC_008253.1 2160924 2162360 R mannose-1-phosphate guanylyltransferase complement(2160924..2162360) Escherichia coli 536 4188817 YP_669990.1 CDS ECP_2090 NC_008253.1 2162363 2163586 R glycosyl transferase family protein complement(2162363..2163586) Escherichia coli 536 4188818 YP_669991.1 CDS ECP_2091 NC_008253.1 2163583 2164062 R GDP-mannose mannosyl hydrolase complement(2163583..2164062) Escherichia coli 536 4188819 YP_669992.1 CDS ECP_2092 NC_008253.1 2164065 2165030 R GDP-fucose synthetase complement(2164065..2165030) Escherichia coli 536 4188820 YP_669993.1 CDS ECP_2093 NC_008253.1 2165033 2166154 R GDP-mannose 4,6-dehydratase complement(2165033..2166154) Escherichia coli 536 4188821 YP_669994.1 CDS ECP_2094 NC_008253.1 2166181 2166729 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2166181..2166729) Escherichia coli 536 4188822 YP_669995.1 CDS ECP_2095 NC_008253.1 2166745 2167491 R glycosyl transferase family protein complement(2166745..2167491) Escherichia coli 536 4188823 YP_669996.1 CDS wcaD NC_008253.1 2167502 2168719 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2167502..2168719) Escherichia coli 536 4188824 YP_669997.1 CDS ECP_2097 NC_008253.1 2168694 2169911 R glycosyl transferase family protein complement(2168694..2169911) Escherichia coli 536 4187717 YP_669998.1 CDS ECP_2098 NC_008253.1 2169908 2170396 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2169908..2170396) Escherichia coli 536 4187718 YP_669999.1 CDS ECP_2099 NC_008253.1 2170399 2171238 R glycosyl transferase family protein complement(2170399..2171238) Escherichia coli 536 4187719 YP_670000.1 CDS ECP_2100 NC_008253.1 2171331 2173493 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2171331..2173493) Escherichia coli 536 4187720 YP_670001.1 CDS ECP_2101 NC_008253.1 2173496 2173939 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2173496..2173939) Escherichia coli 536 4187721 YP_670002.1 CDS ECP_2102 NC_008253.1 2173945 2175084 R polysaccharide export protein wza complement(2173945..2175084) Escherichia coli 536 4187722 YP_670003.1 CDS ECP_2103 NC_008253.1 2175743 2177326 D hypothetical protein 2175743..2177326 Escherichia coli 536 4187723 YP_670004.1 CDS ECP_2104 NC_008253.1 2177619 2179472 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2177619..2179472) Escherichia coli 536 4187724 YP_670005.1 CDS dcd NC_008253.1 2179494 2180075 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2179494..2180075) Escherichia coli 536 4187725 YP_670006.1 CDS ECP_2106 NC_008253.1 2180167 2180808 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2180167..2180808) Escherichia coli 536 4187726 YP_670007.1 CDS ECP_2107 NC_008253.1 2181126 2184443 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2181126..2184443 Escherichia coli 536 4187727 YP_670008.1 CDS ECP_2108 NC_008253.1 2184553 2185401 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2184553..2185401) Escherichia coli 536 4187728 YP_670009.1 CDS ECP_2109 NC_008253.1 2185535 2186887 D chaperone 2185535..2186887 Escherichia coli 536 4187729 YP_670010.1 CDS ECP_2110 NC_008253.1 2186900 2188840 R hypothetical protein complement(2186900..2188840) Escherichia coli 536 4187730 YP_670011.1 CDS ECP_2111 NC_008253.1 2188837 2189598 R hypothetical protein complement(2188837..2189598) Escherichia coli 536 4187731 YP_670012.1 CDS ECP_2112 NC_008253.1 2189595 2189759 R hypothetical protein complement(2189595..2189759) Escherichia coli 536 4187732 YP_670013.1 CDS ECP_2113 NC_008253.1 2189838 2190254 R hypothetical protein complement(2189838..2190254) Escherichia coli 536 4187733 YP_670014.1 CDS ECP_2114 NC_008253.1 2191135 2192382 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2191135..2192382 Escherichia coli 536 4187734 YP_670015.1 CDS ECP_2115 NC_008253.1 2192382 2195504 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2192382..2195504 Escherichia coli 536 4187735 YP_670016.1 CDS ECP_2116 NC_008253.1 2195505 2198582 D efflux transporter; Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2195505..2198582 Escherichia coli 536 4187736 YP_670017.1 CDS ECP_2117 NC_008253.1 2198583 2199998 D multidrug efflux system protein MdtE 2198583..2199998 Escherichia coli 536 4191668 YP_670018.1 CDS ECP_2118 NC_008253.1 2199995 2201398 D signal transduction histidine-protein kinase BaeS 2199995..2201398 Escherichia coli 536 4191669 YP_670019.1 CDS ECP_2119 NC_008253.1 2201395 2202117 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2201395..2202117 Escherichia coli 536 4191670 YP_670020.1 CDS ECP_2120 NC_008253.1 2202297 2202629 D hypothetical protein 2202297..2202629 Escherichia coli 536 4191671 YP_670021.1 CDS ECP_2121 NC_008253.1 2202754 2203368 R hypothetical protein complement(2202754..2203368) Escherichia coli 536 4191672 YP_670022.1 CDS ECP_2122 NC_008253.1 2203420 2205528 R hypothetical protein complement(2203420..2205528) Escherichia coli 536 4191673 YP_670023.1 CDS ECP_2123 NC_008253.1 2205539 2206255 R hypothetical protein complement(2205539..2206255) Escherichia coli 536 4191674 YP_670024.1 CDS ECP_2124 NC_008253.1 2206255 2207469 R hypothetical protein complement(2206255..2207469) Escherichia coli 536 4191675 YP_670025.1 CDS ECP_2125 NC_008253.1 2207957 2209318 D protease YegQ 2207957..2209318 Escherichia coli 536 4191676 YP_670026.1 CDS ECP_2126 NC_008253.1 2209818 2210135 R hypothetical protein complement(2209818..2210135) Escherichia coli 536 4191677 YP_670027.1 CDS ECP_2127 NC_008253.1 2210551 2211450 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2210551..2211450 Escherichia coli 536 4191678 YP_670028.1 CDS ECP_2128 NC_008253.1 2211532 2212305 R galactitol utilization operon repressor complement(2211532..2212305) Escherichia coli 536 4191679 YP_670029.1 CDS ECP_2129 NC_008253.1 2212411 2213358 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2212411..2213358) Escherichia coli 536 4191680 YP_670030.1 CDS ECP_2130 NC_008253.1 2213500 2214855 R PTS system galactitol-specific transporter subunit IIC complement(2213500..2214855) Escherichia coli 536 4191681 YP_670031.1 CDS ECP_2131 NC_008253.1 2214859 2215143 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; galactitol-specific PTS system component IIB complement(2214859..2215143) Escherichia coli 536 4191682 YP_670032.1 CDS ECP_2132 NC_008253.1 2215174 2215626 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; galactitol-specific PTS system component IIA complement(2215174..2215626) Escherichia coli 536 4191683 YP_670033.1 CDS ECP_2133 NC_008253.1 2215636 2216898 R tagatose 6-phosphate kinase gatZ complement(2215636..2216898) Escherichia coli 536 4191684 YP_670034.1 CDS gatY NC_008253.1 2216927 2217781 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2216927..2217781) Escherichia coli 536 4191685 YP_670035.1 CDS ECP_2135 NC_008253.1 2218008 2219060 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2218008..2219060) Escherichia coli 536 4191686 YP_670036.1 CDS ECP_2136 NC_008253.1 2219317 2220594 D nucleoside transporter YegT 2219317..2220594 Escherichia coli 536 4187641 YP_670037.1 CDS ECP_2137 NC_008253.1 2220591 2221595 D hypothetical protein 2220591..2221595 Escherichia coli 536 4187642 YP_670038.1 CDS ECP_2138 NC_008253.1 2221592 2222557 D sugar kinase 2221592..2222557 Escherichia coli 536 4187643 YP_670039.1 CDS ECP_2139 NC_008253.1 2222531 2223277 R transcriptional regulator YegW complement(2222531..2223277) Escherichia coli 536 4187644 YP_670040.1 CDS ECP_2140 NC_008253.1 2223329 2224147 R hypothetical protein complement(2223329..2224147) Escherichia coli 536 4187645 YP_670041.1 CDS ECP_2141 NC_008253.1 2224212 2225012 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2224212..2225012) Escherichia coli 536 4187646 YP_670042.1 CDS ECP_2142 NC_008253.1 2225009 2225797 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2225009..2225797) Escherichia coli 536 4187647 YP_670043.1 CDS ECP_2143 NC_008253.1 2226020 2226292 R hypothetical protein complement(2226020..2226292) Escherichia coli 536 4187648 YP_670044.1 CDS ECP_2144 NC_008253.1 2226413 2227237 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2226413..2227237 Escherichia coli 536 4187649 YP_670045.1 CDS ECP_2145 NC_008253.1 2227456 2227794 D hypothetical protein 2227456..2227794 Escherichia coli 536 4187650 YP_670046.1 CDS ECP_2146 NC_008253.1 2227876 2228910 R hypothetical protein complement(2227876..2228910) Escherichia coli 536 4187651 YP_670047.1 CDS ECP_2147 NC_008253.1 2228926 2231406 R outer membrane usher protein YehB complement(2228926..2231406) Escherichia coli 536 4187652 YP_670048.1 CDS ECP_2148 NC_008253.1 2231422 2232096 R fimbrial chaperone complement(2231422..2232096) Escherichia coli 536 4187653 YP_670049.1 CDS ECP_2149 NC_008253.1 2232177 2232719 R hypothetical protein complement(2232177..2232719) Escherichia coli 536 4187654 YP_670050.1 CDS ECP_2150 NC_008253.1 2233013 2233294 R hypothetical protein complement(2233013..2233294) Escherichia coli 536 4187655 YP_670051.1 CDS ECP_2151 NC_008253.1 2233557 2234666 R ATPase complement(2233557..2234666) Escherichia coli 536 4187656 YP_670052.1 CDS metG NC_008253.1 2234789 2236831 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2234789..2236831 Escherichia coli 536 4187657 YP_670053.1 CDS ECP_2153 NC_008253.1 2236972 2240760 D molybdate metabolism regulator 2236972..2240760 Escherichia coli 536 4187658 YP_670054.1 CDS ECP_2154 NC_008253.1 2240770 2244402 D hypothetical protein 2240770..2244402 Escherichia coli 536 4187659 YP_670055.1 CDS ECP_2155 NC_008253.1 2244463 2244648 D hypothetical protein 2244463..2244648 Escherichia coli 536 4187660 YP_670056.1 CDS ECP_2156 NC_008253.1 2245483 2246571 D hypothetical protein 2245483..2246571 Escherichia coli 536 4191170 YP_670057.1 CDS ECP_2157 NC_008253.1 2246582 2248861 D hypothetical protein 2246582..2248861 Escherichia coli 536 4191171 YP_670058.1 CDS ECP_2158 NC_008253.1 2248854 2249990 D hypothetical protein 2248854..2249990 Escherichia coli 536 4191172 YP_670059.1 CDS ECP_2159 NC_008253.1 2249987 2251777 D hypothetical protein 2249987..2251777 Escherichia coli 536 4191173 YP_670060.1 CDS ECP_2160 NC_008253.1 2251740 2251976 D hypothetical protein 2251740..2251976 Escherichia coli 536 4191174 YP_670061.1 CDS ECP_2161 NC_008253.1 2252101 2252562 D lipoprotein YehR 2252101..2252562 Escherichia coli 536 4191175 YP_670062.1 CDS ECP_2162 NC_008253.1 2252603 2253073 R hypothetical protein complement(2252603..2253073) Escherichia coli 536 4191176 YP_670063.1 CDS ECP_2163 NC_008253.1 2253120 2253839 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2253120..2253839) Escherichia coli 536 4191177 YP_670064.1 CDS ECP_2164 NC_008253.1 2253836 2255521 R hypothetical protein complement(2253836..2255521) Escherichia coli 536 4191178 YP_670065.1 CDS ECP_2165 NC_008253.1 2255743 2256474 D MerR family transcriptional regulator 2255743..2256474 Escherichia coli 536 4191179 YP_670066.1 CDS ECP_2166 NC_008253.1 2256534 2256641 D hypothetical protein 2256534..2256641 Escherichia coli 536 4191180 YP_670067.1 CDS ECP_2167 NC_008253.1 2256622 2257353 R ABC transporter permease complement(2256622..2257353) Escherichia coli 536 4191181 YP_670068.1 CDS ECP_2168 NC_008253.1 2257497 2258285 R ABC transporter ATP-binding protein complement(2257497..2258285) Escherichia coli 536 4191182 YP_670069.1 CDS ECP_2169 NC_008253.1 2258278 2259435 R ABC transporter permease complement(2258278..2259435) Escherichia coli 536 4191183 YP_670070.1 CDS ECP_2170 NC_008253.1 2259442 2260359 R hypothetical protein complement(2259442..2260359) Escherichia coli 536 4191184 YP_670071.1 CDS ECP_2171 NC_008253.1 2260549 2262918 R periplasmic beta-glucosidase complement(2260549..2262918) Escherichia coli 536 4191185 YP_670072.1 CDS ECP_2172 NC_008253.1 2263042 2264757 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2263042..2264757 Escherichia coli 536 4191186 YP_670073.1 CDS pbpG NC_008253.1 2264796 2265737 R penicillin-binding protein 7 precursor; specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2264796..2265737) Escherichia coli 536 4191187 YP_670074.1 CDS ECP_2174 NC_008253.1 2265902 2266489 R hypothetical protein complement(2265902..2266489) Escherichia coli 536 4191188 YP_670075.1 CDS ECP_2175 NC_008253.1 2266659 2267237 D DedA family membrane protein 2266659..2267237 Escherichia coli 536 4189830 YP_670076.1 CDS ECP_2176 NC_008253.1 2267357 2268118 R acetoin dehydrogenase complement(2267357..2268118) Escherichia coli 536 4189831 YP_670077.1 CDS ECP_2177 NC_008253.1 2268171 2269688 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2268171..2269688) Escherichia coli 536 4189832 YP_670078.1 CDS ECP_2178 NC_008253.1 2270066 2270275 R hypothetical protein complement(2270066..2270275) Escherichia coli 536 4189833 YP_670079.1 CDS ECP_2179 NC_008253.1 2270303 2271253 R tRNA-dihydrouridine synthase C complement(2270303..2271253) Escherichia coli 536 4189834 YP_670080.1 CDS ECP_2180 NC_008253.1 2271492 2271890 D hypothetical protein 2271492..2271890 Escherichia coli 536 4189835 YP_670081.1 CDS ECP_2181 NC_008253.1 2271887 2272582 D hypothetical protein 2271887..2272582 Escherichia coli 536 4189836 YP_670082.1 CDS ECP_2182 NC_008253.1 2272712 2273596 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2272712..2273596 Escherichia coli 536 4189837 YP_670083.1 CDS ECP_2183 NC_008253.1 2273746 2274465 D hypothetical protein 2273746..2274465 Escherichia coli 536 4189838 YP_670084.1 CDS ECP_2184 NC_008253.1 2274468 2274707 D hypothetical protein 2274468..2274707 Escherichia coli 536 4189839 YP_670085.1 CDS ECP_2185 NC_008253.1 2274901 2276139 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2274901..2276139 Escherichia coli 536 4189840 YP_670086.1 CDS ECP_2186 NC_008253.1 2276133 2277368 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2276133..2277368 Escherichia coli 536 4189841 YP_670087.1 CDS mglC NC_008253.1 2277611 2278621 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2277611..2278621) Escherichia coli 536 4189842 YP_670088.1 CDS ECP_2188 NC_008253.1 2278637 2280157 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2278637..2280157) Escherichia coli 536 4189843 YP_670089.1 CDS ECP_2189 NC_008253.1 2280218 2281216 R D-galactose-binding periplasmic protein complement(2280218..2281216) Escherichia coli 536 4189844 YP_670090.1 CDS ECP_2190 NC_008253.1 2281496 2282536 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2281496..2282536) Escherichia coli 536 4189845 YP_670091.1 CDS ECP_2191 NC_008253.1 2282526 2282729 D hypothetical protein 2282526..2282729 Escherichia coli 536 4189846 YP_670092.1 CDS ECP_2192 NC_008253.1 2282678 2283952 R hypothetical protein complement(2282678..2283952) Escherichia coli 536 4189847 YP_670093.1 CDS folE NC_008253.1 2283852 2284520 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2283852..2284520) Escherichia coli 536 4189848 YP_670094.1 CDS ECP_2194 NC_008253.1 2284778 2285614 D hypothetical protein 2284778..2285614 Escherichia coli 536 4189849 YP_670095.1 CDS ECP_2195 NC_008253.1 2285646 2287637 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2285646..2287637) Escherichia coli 536 4187378 YP_670096.1 CDS ECP_2196 NC_008253.1 2287929 2289398 R lysine transporter complement(2287929..2289398) Escherichia coli 536 4187379 YP_670097.1 CDS ECP_2197 NC_008253.1 2289603 2290484 R DNA-binding transcriptional regulator complement(2289603..2290484) Escherichia coli 536 4187380 YP_670098.1 CDS ECP_2198 NC_008253.1 2290583 2291632 D hypothetical protein 2290583..2291632 Escherichia coli 536 4187381 YP_670099.1 CDS ECP_2199 NC_008253.1 2291706 2292563 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2291706..2292563 Escherichia coli 536 4187382 YP_670100.1 CDS ECP_2200 NC_008253.1 2292567 2293655 D hypothetical protein 2292567..2293655 Escherichia coli 536 4187383 YP_670101.1 CDS ECP_2201 NC_008253.1 2293757 2294962 R Na+ dependent nucleoside transporter-family protein complement(2293757..2294962) Escherichia coli 536 4187384 YP_670102.1 CDS rihB NC_008253.1 2295062 2296003 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2295062..2296003) Escherichia coli 536 4187385 YP_670103.1 CDS ECP_2203 NC_008253.1 2296172 2296831 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2296172..2296831 Escherichia coli 536 4187386 YP_670104.1 CDS ECP_2204 NC_008253.1 2296898 2298148 R Na+ dependent nucleoside transporter-family protein complement(2296898..2298148) Escherichia coli 536 4187387 YP_670105.1 CDS ECP_2205 NC_008253.1 2298242 2299180 R hypothetical protein complement(2298242..2299180) Escherichia coli 536 4187388 YP_670106.1 CDS ECP_2206 NC_008253.1 2299168 2300109 R hypothetical protein complement(2299168..2300109) Escherichia coli 536 4187389 YP_670107.1 CDS ECP_2207 NC_008253.1 2300565 2302256 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2300565..2302256) Escherichia coli 536 4187390 YP_670108.1 CDS fruK NC_008253.1 2302273 2303211 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2302273..2303211) Escherichia coli 536 4187391 YP_670109.1 CDS ECP_2209 NC_008253.1 2303211 2304341 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional fructose-specific PTS IIA/HPr protein complement(2303211..2304341) Escherichia coli 536 4187392 YP_670110.1 CDS ECP_2210 NC_008253.1 2304709 2305890 D sugar efflux transporter B 2304709..2305890 Escherichia coli 536 4187393 YP_670111.1 CDS ECP_2211 NC_008253.1 2305887 2306141 R hypothetical protein complement(2305887..2306141) Escherichia coli 536 4187394 YP_670112.1 CDS ECP_2212 NC_008253.1 2306296 2306868 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2306296..2306868 Escherichia coli 536 4187395 YP_670113.1 CDS ECP_2213 NC_008253.1 2307091 2308557 D oxidoreductase YeiQ 2307091..2308557 Escherichia coli 536 4187396 YP_670114.1 CDS ECP_2214 NC_008253.1 2308675 2309661 D cobalamin synthesis protein 2308675..2309661 Escherichia coli 536 4189278 YP_670115.1 CDS ECP_2215 NC_008253.1 2309700 2310413 D hypothetical protein 2309700..2310413 Escherichia coli 536 4189279 YP_670116.1 CDS spr NC_008253.1 2310825 2311391 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2310825..2311391 Escherichia coli 536 4189280 YP_670117.1 CDS ECP_2217 NC_008253.1 2311572 2313128 D hypothetical protein 2311572..2313128 Escherichia coli 536 4189281 YP_670118.1 CDS ECP_2218 NC_008253.1 2313210 2315024 D hypothetical protein 2313210..2315024 Escherichia coli 536 4189282 YP_670119.1 CDS ECP_2219 NC_008253.1 2315025 2316119 D ABC transporter permease 2315025..2316119 Escherichia coli 536 4189283 YP_670120.1 CDS ECP_2220 NC_008253.1 2316119 2317144 D ABC transporter permease 2316119..2317144 Escherichia coli 536 4189284 YP_670121.1 CDS ECP_2221 NC_008253.1 2317146 2318735 D ABC transporter ATP-binding protein 2317146..2318735 Escherichia coli 536 4189285 YP_670122.1 CDS ECP_2222 NC_008253.1 2318739 2319083 R hypothetical protein complement(2318739..2319083) Escherichia coli 536 4189286 YP_670123.1 CDS ECP_2223 NC_008253.1 2319416 2320606 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2319416..2320606) Escherichia coli 536 4189287 YP_670124.1 CDS ECP_2224 NC_008253.1 2320634 2321329 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2320634..2321329) Escherichia coli 536 4189288 YP_670125.1 CDS ECP_2225 NC_008253.1 2321479 2323239 D hypothetical protein 2321479..2323239 Escherichia coli 536 4189289 YP_670126.1 CDS ECP_2226 NC_008253.1 2323364 2323648 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2323364..2323648 Escherichia coli 536 4189290 YP_670127.1 CDS ECP_2227 NC_008253.1 2323787 2324794 R nucleoid-associated protein NdpA complement(2323787..2324794) Escherichia coli 536 4189291 YP_670128.1 CDS ECP_2228 NC_008253.1 2324976 2325203 D hypothetical protein 2324976..2325203 Escherichia coli 536 4189292 YP_670129.1 CDS ECP_2229 NC_008253.1 2325223 2326983 D sulfatase 2325223..2326983 Escherichia coli 536 4189293 YP_670130.1 CDS ECP_2231 NC_008253.1 2327372 2327470 R hypothetical protein complement(2327372..2327470) Escherichia coli 536 4189295 YP_670131.1 CDS ECP_2232 NC_008253.1 2327473 2327862 R hypothetical protein complement(2327473..2327862) Escherichia coli 536 4189296 YP_670132.1 CDS ECP_2233 NC_008253.1 2328265 2328912 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2328265..2328912 Escherichia coli 536 4191745 YP_670133.1 CDS ECP_2234 NC_008253.1 2328947 2329831 R cytochrome c-type biogenesis protein CcmH complement(2328947..2329831) Escherichia coli 536 4191746 YP_670134.1 CDS ECP_2235 NC_008253.1 2329923 2330552 R thiol:disulfide interchange protein DsbE complement(2329923..2330552) Escherichia coli 536 4191747 YP_670135.1 CDS ECP_2236 NC_008253.1 2330549 2332492 R cytochrome c-type biogenesis protein CcmF complement(2330549..2332492) Escherichia coli 536 4191748 YP_670136.1 CDS ECP_2237 NC_008253.1 2332489 2332968 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2332489..2332968) Escherichia coli 536 4191749 YP_670137.1 CDS ECP_2238 NC_008253.1 2332965 2333174 R heme exporter protein D; cytochrome c-type biogenesis protein CcmD complement(2332965..2333174) Escherichia coli 536 4191750 YP_670138.1 CDS ECP_2241 NC_008253.1 2333951 2334613 R heme exporter protein B; cytochrome c-type biogenesis protein CcmB complement(2333951..2334613) Escherichia coli 536 4191753 YP_670139.1 CDS ECP_2242 NC_008253.1 2334610 2335227 R heme exporter protein A; ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2334610..2335227) Escherichia coli 536 4191754 YP_670140.1 CDS ECP_2243 NC_008253.1 2335246 2335848 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2335246..2335848) Escherichia coli 536 4191755 YP_670141.1 CDS napB NC_008253.1 2335858 2336307 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2335858..2336307) Escherichia coli 536 4191756 YP_670142.1 CDS napH NC_008253.1 2336304 2337167 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2336304..2337167) Escherichia coli 536 4191757 YP_670143.1 CDS napG NC_008253.1 2337154 2337849 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2337154..2337849) Escherichia coli 536 4191758 YP_670144.1 CDS ECP_2247 NC_008253.1 2337856 2340342 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2337856..2340342) Escherichia coli 536 4191759 YP_670145.1 CDS ECP_2248 NC_008253.1 2340339 2340602 R assembly protein for periplasmic nitrate reductase complement(2340339..2340602) Escherichia coli 536 4191760 YP_670146.1 CDS ECP_2249 NC_008253.1 2340592 2341086 R Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein complement(2340592..2341086) Escherichia coli 536 4191761 YP_670147.1 CDS ECP_2250 NC_008253.1 2341195 2341359 D hypothetical protein 2341195..2341359 Escherichia coli 536 4190121 YP_670148.1 CDS ECP_2251 NC_008253.1 2341494 2341982 D ecotin 2341494..2341982 Escherichia coli 536 4190122 YP_670149.1 CDS ECP_2252 NC_008253.1 2342132 2343760 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2342132..2343760) Escherichia coli 536 4190123 YP_670150.1 CDS ECP_2253 NC_008253.1 2343996 2344652 R similar to C-terminal part of ATP-binding protein YojI; ABC transporter complement(2343996..2344652) Escherichia coli 536 4190124 YP_670151.1 CDS ECP_2254 NC_008253.1 2344656 2345639 R similar to N-terminal part of ATP-binding protein YojI; ABC transporter complement(2344656..2345639) Escherichia coli 536 4190125 YP_670152.1 CDS ECP_2255 NC_008253.1 2345715 2346365 R alkylated DNA repair protein AlkB complement(2345715..2346365) Escherichia coli 536 4190126 YP_670153.1 CDS ECP_2256 NC_008253.1 2346365 2347429 R ADA regulatory protein complement(2346365..2347429) Escherichia coli 536 4190127 YP_670154.1 CDS ECP_2257 NC_008253.1 2347503 2348558 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2347503..2348558) Escherichia coli 536 4190128 YP_670155.1 CDS ECP_2258 NC_008253.1 2348670 2349797 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2348670..2349797) Escherichia coli 536 4190129 YP_670156.1 CDS ECP_2259 NC_008253.1 2350536 2353208 D phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2350536..2353208 Escherichia coli 536 4190130 YP_670157.1 CDS ECP_2260 NC_008253.1 2353225 2353875 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2353225..2353875 Escherichia coli 536 4190131 YP_670158.1 CDS ECP_2261 NC_008253.1 2354075 2356924 R hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2354075..2356924) Escherichia coli 536 4190132 YP_670159.1 CDS ECP_2262 NC_008253.1 2357091 2358917 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2357091..2358917 Escherichia coli 536 4190133 YP_670160.1 CDS ECP_2263 NC_008253.1 2358914 2360299 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2358914..2360299 Escherichia coli 536 4190134 YP_670161.1 CDS ECP_2266 NC_008253.1 2361158 2361808 D acetate CoA-transferase subunit beta 2361158..2361808 Escherichia coli 536 4190137 YP_670162.1 CDS ECP_2267 NC_008253.1 2361805 2363127 D short-chain fatty acids transporter 2361805..2363127 Escherichia coli 536 4191916 YP_670163.1 CDS ECP_2268 NC_008253.1 2363158 2364342 D acetyl-CoA acetyltransferase 2363158..2364342 Escherichia coli 536 4191917 YP_670164.1 CDS ECP_2269 NC_008253.1 2364416 2365192 R hypothetical protein complement(2364416..2365192) Escherichia coli 536 4191918 YP_670165.1 CDS ECP_2270 NC_008253.1 2365197 2366846 R hypothetical protein complement(2365197..2366846) Escherichia coli 536 4191919 YP_670166.1 CDS ECP_2271 NC_008253.1 2366847 2371451 R hypothetical protein complement(2366847..2371451) Escherichia coli 536 4191920 YP_670167.1 CDS ECP_2272 NC_008253.1 2371385 2372008 R hypothetical protein complement(2371385..2372008) Escherichia coli 536 4191921 YP_670168.1 CDS ECP_2273 NC_008253.1 2372005 2373693 R hypothetical protein complement(2372005..2373693) Escherichia coli 536 4191922 YP_670169.1 CDS ECP_2274 NC_008253.1 2373842 2376469 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2373842..2376469) Escherichia coli 536 4191923 YP_670170.1 CDS ECP_2275 NC_008253.1 2376616 2377338 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2376616..2377338 Escherichia coli 536 4191924 YP_670171.1 CDS ECP_2276 NC_008253.1 2377478 2381242 R adhesin complement(2377478..2381242) Escherichia coli 536 4191925 YP_670172.1 CDS ECP_2277 NC_008253.1 2381918 2384203 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2381918..2384203 Escherichia coli 536 4191926 YP_670173.1 CDS nrdB NC_008253.1 2384393 2385523 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2384393..2385523 Escherichia coli 536 4191927 YP_670174.1 CDS ECP_2279 NC_008253.1 2385523 2385777 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2385523..2385777 Escherichia coli 536 4191928 YP_670175.1 CDS ECP_2280 NC_008253.1 2385831 2386481 R PH-inducible protein involved in stress response; hypothetical protein complement(2385831..2386481) Escherichia coli 536 4191929 YP_670176.1 CDS glpQ NC_008253.1 2386684 2387691 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2386684..2387691) Escherichia coli 536 4191930 YP_670177.1 CDS glpT NC_008253.1 2387765 2389123 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2387765..2389123) Escherichia coli 536 4191931 YP_670178.1 CDS glpA NC_008253.1 2389396 2391024 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2389396..2391024 Escherichia coli 536 4191932 YP_670179.1 CDS ECP_2284 NC_008253.1 2391014 2392195 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2391014..2392195 Escherichia coli 536 4191933 YP_670180.1 CDS glpC NC_008253.1 2392270 2393460 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2392270..2393460 Escherichia coli 536 4191934 YP_670181.1 CDS ECP_2286 NC_008253.1 2393653 2394612 D hypothetical protein 2393653..2394612 Escherichia coli 536 4191935 YP_670182.1 CDS ECP_2287 NC_008253.1 2394625 2394810 D hypothetical protein 2394625..2394810 Escherichia coli 536 4190334 YP_670183.1 CDS ECP_2288 NC_008253.1 2394851 2395654 R aldolase complement(2394851..2395654) Escherichia coli 536 4190335 YP_670184.1 CDS ECP_2289 NC_008253.1 2395672 2396961 R transmembrane transporter YfaV complement(2395672..2396961) Escherichia coli 536 4190336 YP_670185.1 CDS ECP_2290 NC_008253.1 2397018 2398235 R hypothetical protein complement(2397018..2398235) Escherichia coli 536 4190337 YP_670186.1 CDS ECP_2291 NC_008253.1 2398238 2399020 R transcriptional regulator YfaX complement(2398238..2399020) Escherichia coli 536 4190338 YP_670187.1 CDS ECP_2292 NC_008253.1 2399240 2400442 R competence damage-inducible protein A complement(2399240..2400442) Escherichia coli 536 4190339 YP_670188.1 CDS ECP_2293 NC_008253.1 2400542 2401084 R hypothetical protein complement(2400542..2401084) Escherichia coli 536 4190340 YP_670189.1 CDS ECP_2294 NC_008253.1 2401364 2401789 D nudix hydrolase YfaO 2401364..2401789 Escherichia coli 536 4190341 YP_670190.1 CDS ECP_2295 NC_008253.1 2401828 2402430 R aluminum resistance protein complement(2401828..2402430) Escherichia coli 536 4190342 YP_670191.1 CDS ECP_2296 NC_008253.1 2402720 2403877 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2402720..2403877 Escherichia coli 536 4190343 YP_670192.1 CDS ECP_2297 NC_008253.1 2403881 2404849 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2403881..2404849 Escherichia coli 536 4190344 YP_670193.1 CDS ECP_2298 NC_008253.1 2404849 2406831 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2404849..2406831 Escherichia coli 536 4190345 YP_670194.1 CDS ECP_2299 NC_008253.1 2406828 2407718 D hypothetical protein 2406828..2407718 Escherichia coli 536 4190346 YP_670195.1 CDS arnT NC_008253.1 2407718 2409370 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2407718..2409370 Escherichia coli 536 4190347 YP_670196.1 CDS ECP_2301 NC_008253.1 2409367 2409702 D hypothetical protein 2409367..2409702 Escherichia coli 536 4190348 YP_670197.1 CDS ECP_2302 NC_008253.1 2409702 2410088 D hypothetical protein 2409702..2410088 Escherichia coli 536 4190349 YP_670198.1 CDS ECP_2303 NC_008253.1 2410082 2410348 R polymyxin B resistance protein pmrD complement(2410082..2410348) Escherichia coli 536 4190350 YP_670199.1 CDS ECP_2304 NC_008253.1 2410458 2411813 R O-succinylbenzoic acid--CoA ligase complement(2410458..2411813) Escherichia coli 536 4190351 YP_670200.1 CDS ECP_2305 NC_008253.1 2411810 2412772 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2411810..2412772) Escherichia coli 536 4190352 YP_670201.1 CDS ECP_2306 NC_008253.1 2412772 2413629 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2412772..2413629) Escherichia coli 536 4191442 YP_670202.1 CDS ECP_2307 NC_008253.1 2413644 2414402 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(2413644..2414402) Escherichia coli 536 4191443 YP_670203.1 CDS ECP_2308 NC_008253.1 2414399 2416258 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2414399..2416258) Escherichia coli 536 4191444 YP_670204.1 CDS ECP_2309 NC_008253.1 2416158 2417453 R menaquinone-specific isochorismate synthase complement(2416158..2417453) Escherichia coli 536 4191445 YP_670205.1 CDS ECP_2310 NC_008253.1 2417532 2417837 R hypothetical protein complement(2417532..2417837) Escherichia coli 536 4191446 YP_670206.1 CDS ECP_2311 NC_008253.1 2417892 2418353 R hypothetical protein complement(2417892..2418353) Escherichia coli 536 4191447 YP_670207.1 CDS ECP_2312 NC_008253.1 2418418 2419335 D member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2418418..2419335 Escherichia coli 536 4191448 YP_670208.1 CDS ECP_2313 NC_008253.1 2419691 2420662 D hypothetical protein 2419691..2420662 Escherichia coli 536 4191449 YP_670209.1 CDS ECP_2314 NC_008253.1 2420765 2421268 D hypothetical protein 2420765..2421268 Escherichia coli 536 4191450 YP_670210.1 CDS ECP_2315 NC_008253.1 2421335 2422792 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2421335..2422792) Escherichia coli 536 4191451 YP_670211.1 CDS ECP_2316 NC_008253.1 2422799 2424328 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2422799..2424328) Escherichia coli 536 4191452 YP_670212.1 CDS ECP_2317 NC_008253.1 2424492 2426333 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2424492..2426333) Escherichia coli 536 4191453 YP_670213.1 CDS ECP_2318 NC_008253.1 2426330 2426632 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2426330..2426632) Escherichia coli 536 4191454 YP_670214.1 CDS ECP_2319 NC_008253.1 2426629 2427183 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2426629..2427183) Escherichia coli 536 4191455 YP_670215.1 CDS ECP_2320 NC_008253.1 2427195 2427737 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2427195..2427737) Escherichia coli 536 4191456 YP_670216.1 CDS ECP_2321 NC_008253.1 2427752 2428729 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2427752..2428729) Escherichia coli 536 4191457 YP_670217.1 CDS ECP_2322 NC_008253.1 2428726 2431458 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2428726..2431458) Escherichia coli 536 4191458 YP_670218.1 CDS ECP_2323 NC_008253.1 2431505 2432842 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2431505..2432842) Escherichia coli 536 4191459 YP_670219.1 CDS ECP_2324 NC_008253.1 2432839 2433339 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2432839..2433339) Escherichia coli 536 4191460 YP_670220.1 CDS ECP_2325 NC_008253.1 2433342 2435132 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2433342..2435132) Escherichia coli 536 4191461 YP_670221.1 CDS ECP_2326 NC_008253.1 2435238 2435900 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2435238..2435900) Escherichia coli 536 4189352 YP_670222.1 CDS ECP_2327 NC_008253.1 2435916 2436359 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2435916..2436359) Escherichia coli 536 4189353 YP_670223.1 CDS ECP_2328 NC_008253.1 2436989 2437927 R transcriptional regulator lrhA complement(2436989..2437927) Escherichia coli 536 4189354 YP_670224.1 CDS ECP_2329 NC_008253.1 2438847 2440064 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2438847..2440064 Escherichia coli 536 4189355 YP_670225.1 CDS ECP_2330 NC_008253.1 2440148 2440747 D hypothetical protein 2440148..2440747 Escherichia coli 536 4189356 YP_670226.1 CDS ECP_2331 NC_008253.1 2440806 2442638 R hypothetical protein complement(2440806..2442638) Escherichia coli 536 4189357 YP_670227.1 CDS ECP_2332 NC_008253.1 2442725 2443375 R phosphatase complement(2442725..2443375) Escherichia coli 536 4189358 YP_670228.1 CDS ECP_2333 NC_008253.1 2443386 2443880 R hypothetical protein complement(2443386..2443880) Escherichia coli 536 4189359 YP_670229.1 CDS ECP_2334 NC_008253.1 2443963 2444418 R hypothetical protein complement(2443963..2444418) Escherichia coli 536 4189360 YP_670230.1 CDS ECP_2335 NC_008253.1 2444756 2445958 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2444756..2445958 Escherichia coli 536 4189361 YP_670231.1 CDS ECP_2336 NC_008253.1 2446033 2448177 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2446033..2448177 Escherichia coli 536 4189362 YP_670232.1 CDS ECP_2337 NC_008253.1 2448367 2449887 D hypothetical protein 2448367..2449887 Escherichia coli 536 4189363 YP_670233.1 CDS ECP_2338 NC_008253.1 2449921 2450463 R hypothetical protein complement(2449921..2450463) Escherichia coli 536 4189364 YP_670234.1 CDS ECP_2339 NC_008253.1 2450521 2451072 R phosphodiesterase complement(2450521..2451072) Escherichia coli 536 4189365 YP_670235.1 CDS ECP_2340 NC_008253.1 2451128 2451772 R GST-like protein complement(2451128..2451772) Escherichia coli 536 4189366 YP_670236.1 CDS ECP_2341 NC_008253.1 2451908 2452555 D glutathione S-transferase 2451908..2452555 Escherichia coli 536 4189367 YP_670237.1 CDS folX NC_008253.1 2452612 2452974 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2452612..2452974 Escherichia coli 536 4189368 YP_670238.1 CDS ECP_2343 NC_008253.1 2452995 2453888 D hypothetical protein 2452995..2453888 Escherichia coli 536 4189369 YP_670239.1 CDS ECP_2344 NC_008253.1 2453936 2454826 R hypothetical protein complement(2453936..2454826) Escherichia coli 536 4189370 YP_670240.1 CDS ECP_2345 NC_008253.1 2455022 2455795 R histidine/lysine/arginine/ornithine transporter subunit complement(2455022..2455795) Escherichia coli 536 4191189 YP_670241.1 CDS ECP_2346 NC_008253.1 2455803 2456519 R histidine transport system permease HisM complement(2455803..2456519) Escherichia coli 536 4191190 YP_670242.1 CDS ECP_2347 NC_008253.1 2456556 2457203 R histidine transport system permease HisQ complement(2456556..2457203) Escherichia coli 536 4191191 YP_670243.1 CDS ECP_2348 NC_008253.1 2457293 2458075 R histidine-binding periplasmic protein complement(2457293..2458075) Escherichia coli 536 4191192 YP_670244.1 CDS ECP_2349 NC_008253.1 2458296 2459078 R lysine-arginine-ornithine-binding periplasmic protein complement(2458296..2459078) Escherichia coli 536 4191193 YP_670245.1 CDS ECP_2350 NC_008253.1 2459344 2459913 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2459344..2459913) Escherichia coli 536 4191194 YP_670246.1 CDS ECP_2351 NC_008253.1 2460008 2461525 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2460008..2461525) Escherichia coli 536 4191195 YP_670247.1 CDS ECP_2352 NC_008253.1 2461562 2462050 R membrane protein required for colicin V production; colicin V production protein complement(2461562..2462050) Escherichia coli 536 4191196 YP_670248.1 CDS ECP_2353 NC_008253.1 2462855 2463517 R hypothetical protein complement(2462855..2463517) Escherichia coli 536 4191197 YP_670249.1 CDS ECP_2354 NC_008253.1 2463507 2464775 R bifunctional; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2463507..2464775) Escherichia coli 536 4191198 YP_670250.1 CDS ECP_2355 NC_008253.1 2464845 2465759 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2464845..2465759) Escherichia coli 536 4191199 YP_670251.1 CDS ECP_2356 NC_008253.1 2465915 2466574 R hypothetical protein complement(2465915..2466574) Escherichia coli 536 4191200 YP_670252.1 CDS truA NC_008253.1 2466657 2467469 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2466657..2467469) Escherichia coli 536 4191201 YP_670253.1 CDS ECP_2358 NC_008253.1 2467469 2468482 R semialdehyde dehydrogenase complement(2467469..2468482) Escherichia coli 536 4191202 YP_670254.1 CDS ECP_2359 NC_008253.1 2468548 2469684 R erythronate-4-phosphate dehydrogenase complement(2468548..2469684) Escherichia coli 536 4191203 YP_670255.1 CDS flk NC_008253.1 2469783 2470778 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2469783..2470778 Escherichia coli 536 4191204 YP_670256.1 CDS ECP_2361 NC_008253.1 2470775 2471953 R hypothetical protein complement(2470775..2471953) Escherichia coli 536 4191205 YP_670257.1 CDS ECP_2362 NC_008253.1 2472218 2473438 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2472218..2473438) Escherichia coli 536 4191206 YP_670258.1 CDS mnmC NC_008253.1 2473597 2475603 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2473597..2475603 Escherichia coli 536 4191207 YP_670259.1 CDS ECP_2364 NC_008253.1 2475724 2476002 R hypothetical protein complement(2475724..2476002) Escherichia coli 536 4191208 YP_670260.1 CDS ECP_2365 NC_008253.1 2476036 2476584 R hypothetical protein complement(2476036..2476584) Escherichia coli 536 4188697 YP_670261.1 CDS ECP_2366 NC_008253.1 2476584 2477393 R hypothetical protein complement(2476584..2477393) Escherichia coli 536 4188698 YP_670262.1 CDS mepA NC_008253.1 2477393 2478217 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2477393..2478217) Escherichia coli 536 4188699 YP_670263.1 CDS ECP_2368 NC_008253.1 2478221 2479306 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2478221..2479306) Escherichia coli 536 4188700 YP_670264.1 CDS ECP_2369 NC_008253.1 2479341 2480606 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2479341..2480606) Escherichia coli 536 4188701 YP_670265.1 CDS ECP_2370 NC_008253.1 2480439 2480990 D hypothetical protein 2480439..2480990 Escherichia coli 536 4188702 YP_670266.1 CDS ECP_2371 NC_008253.1 2481407 2482168 R hypothetical protein complement(2481407..2482168) Escherichia coli 536 4188703 YP_670267.1 CDS ECP_2372 NC_008253.1 2482170 2482697 R fimbrial-like protein YfcP complement(2482170..2482697) Escherichia coli 536 4188704 YP_670268.1 CDS ECP_2373 NC_008253.1 2482694 2483173 R fimbrial-like protein YfcQ complement(2482694..2483173) Escherichia coli 536 4188705 YP_670269.1 CDS ECP_2374 NC_008253.1 2483170 2483673 R hypothetical protein complement(2483170..2483673) Escherichia coli 536 4188706 YP_670270.1 CDS ECP_2375 NC_008253.1 2483690 2484442 R fimbrial chaperone complement(2483690..2484442) Escherichia coli 536 4188707 YP_670271.1 CDS ECP_2376 NC_008253.1 2484462 2487116 R outer membrane usher protein YfcU complement(2484462..2487116) Escherichia coli 536 4188708 YP_670272.1 CDS ECP_2377 NC_008253.1 2487191 2487757 R fimbrial-like protein YfcV complement(2487191..2487757) Escherichia coli 536 4188709 YP_670273.1 CDS ECP_2378 NC_008253.1 2488324 2488809 R phosphohistidine phosphatase complement(2488324..2488809) Escherichia coli 536 4188710 YP_670274.1 CDS fadJ NC_008253.1 2489012 2491156 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2489012..2491156) Escherichia coli 536 4188711 YP_670275.1 CDS fadI NC_008253.1 2491156 2492466 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2491156..2492466) Escherichia coli 536 4188712 YP_670276.1 CDS ECP_2381 NC_008253.1 2492646 2492930 R hypothetical protein complement(2492646..2492930) Escherichia coli 536 4188713 YP_670277.1 CDS ECP_2382 NC_008253.1 2493302 2494642 D long-chain fatty acid outer membrane transporter 2493302..2494642 Escherichia coli 536 4188714 YP_670278.1 CDS ECP_2383 NC_008253.1 2494704 2495459 R VacJ lipoprotein precursor complement(2494704..2495459) Escherichia coli 536 4188715 YP_670279.1 CDS ECP_2384 NC_008253.1 2495753 2496685 D transporter protein 2495753..2496685 Escherichia coli 536 4189621 YP_670280.1 CDS lacY NC_008253.1 2497286 2498533 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(2497286..2498533) Escherichia coli 536 4189623 YP_670281.1 CDS ECP_2387 NC_008253.1 2498602 2499519 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(2498602..2499519) Escherichia coli 536 4189624 YP_670282.1 CDS ECP_2388 NC_008253.1 2499735 2501168 D sucrose-6-phosphate hydrolase 2499735..2501168 Escherichia coli 536 4189625 YP_670283.1 CDS ECP_2389 NC_008253.1 2501176 2502171 R sucrose operon repressor complement(2501176..2502171) Escherichia coli 536 4189626 YP_670284.1 CDS ECP_2390 NC_008253.1 2502401 2502619 D hypothetical protein 2502401..2502619 Escherichia coli 536 4189627 YP_670285.1 CDS ECP_2391 NC_008253.1 2502637 2503965 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2502637..2503965 Escherichia coli 536 4189628 YP_670286.1 CDS ECP_2392 NC_008253.1 2504073 2505611 R multidrug resistance protein Y complement(2504073..2505611) Escherichia coli 536 4189629 YP_670287.1 CDS ECP_2393 NC_008253.1 2505611 2506651 R multidrug resistance protein K complement(2505611..2506651) Escherichia coli 536 4189630 YP_670288.1 CDS ECP_2394 NC_008253.1 2507190 2507804 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2507190..2507804 Escherichia coli 536 4189631 YP_670289.1 CDS ECP_2395 NC_008253.1 2507809 2511402 D hybrid sensory histidine kinase in two-component regulatory system with EvgA 2507809..2511402 Escherichia coli 536 4189632 YP_670290.1 CDS ECP_2396 NC_008253.1 2511458 2512603 R hypothetical protein complement(2511458..2512603) Escherichia coli 536 4189633 YP_670291.1 CDS ECP_2397 NC_008253.1 2512677 2513621 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(2512677..2513621) Escherichia coli 536 4189634 YP_670292.1 CDS ECP_2398 NC_008253.1 2513691 2515385 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(2513691..2515385) Escherichia coli 536 4189635 YP_670293.1 CDS ECP_2399 NC_008253.1 2515439 2516689 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2515439..2516689) Escherichia coli 536 4189636 YP_670294.1 CDS ECP_2400 NC_008253.1 2517201 2517668 R hypothetical protein complement(2517201..2517668) Escherichia coli 536 4189637 YP_670295.1 CDS ECP_2401 NC_008253.1 2517891 2518052 D hypothetical protein 2517891..2518052 Escherichia coli 536 4189638 YP_670296.1 CDS ECP_2402 NC_008253.1 2518126 2518401 D lipoprotein YpdI 2518126..2518401 Escherichia coli 536 4189639 YP_670297.1 CDS ECP_2403 NC_008253.1 2518478 2518720 R hypothetical protein complement(2518478..2518720) Escherichia coli 536 4189926 YP_670298.1 CDS ECP_2404 NC_008253.1 2519073 2519993 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2519073..2519993 Escherichia coli 536 4189927 YP_670299.1 CDS ECP_2405 NC_008253.1 2520485 2521723 R aminotransferase complement(2520485..2521723) Escherichia coli 536 4189928 YP_670300.1 CDS ECP_2406 NC_008253.1 2522118 2523797 D hypothetical protein 2522118..2523797 Escherichia coli 536 4189929 YP_670301.1 CDS ECP_2407 NC_008253.1 2523812 2524546 D hypothetical protein 2523812..2524546 Escherichia coli 536 4189930 YP_670302.1 CDS ECP_2408 NC_008253.1 2524559 2525416 D transcriptional regulator YpdC 2524559..2525416 Escherichia coli 536 4189931 YP_670303.1 CDS ECP_2409 NC_008253.1 2525419 2527914 R phosphoenolpyruvate-protein phosphotransferase YpdD complement(2525419..2527914) Escherichia coli 536 4189932 YP_670304.1 CDS ECP_2410 NC_008253.1 2527939 2528976 R metalloprotein; exoaminopeptidase complement(2527939..2528976) Escherichia coli 536 4189933 YP_670305.1 CDS ECP_2411 NC_008253.1 2528976 2530061 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2528976..2530061) Escherichia coli 536 4189934 YP_670306.1 CDS ECP_2412 NC_008253.1 2530077 2531324 R PTS system IIC component YpdG complement(2530077..2531324) Escherichia coli 536 4189935 YP_670307.1 CDS ECP_2413 NC_008253.1 2531346 2531672 R PTS system IIB component YpdH complement(2531346..2531672) Escherichia coli 536 4189936 YP_670308.1 CDS glk NC_008253.1 2531891 2532856 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2531891..2532856) Escherichia coli 536 4189937 YP_670309.1 CDS ECP_2415 NC_008253.1 2533060 2534316 D hypothetical protein 2533060..2534316 Escherichia coli 536 4189938 YP_670310.1 CDS ECP_2416 NC_008253.1 2534431 2534757 D hypothetical protein 2534431..2534757 Escherichia coli 536 4189939 YP_670311.1 CDS ECP_2417 NC_008253.1 2534898 2536136 R manganese transport protein MntH complement(2534898..2536136) Escherichia coli 536 4189940 YP_670312.1 CDS ECP_2418 NC_008253.1 2536472 2537674 D nucleoside permease NupC 2536472..2537674 Escherichia coli 536 4189941 YP_670313.1 CDS ECP_2419 NC_008253.1 2537724 2539973 R hypothetical protein complement(2537724..2539973) Escherichia coli 536 4189942 YP_670314.1 CDS ECP_2420 NC_008253.1 2540531 2540890 D hypothetical protein 2540531..2540890 Escherichia coli 536 4189943 YP_670315.1 CDS ECP_2421 NC_008253.1 2540892 2541284 D hypothetical protein 2540892..2541284 Escherichia coli 536 4189944 YP_670316.1 CDS gltX NC_008253.1 2541335 2542750 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2541335..2542750) Escherichia coli 536 4191540 YP_670317.1 CDS ECP_2427 NC_008253.1 2543517 2544401 R DNA-binding transcriptional activator XapR complement(2543517..2544401) Escherichia coli 536 4191545 YP_670318.1 CDS ECP_2428 NC_008253.1 2544442 2544600 R hypothetical protein complement(2544442..2544600) Escherichia coli 536 4191546 YP_670319.1 CDS ECP_2429 NC_008253.1 2544653 2545909 R xanthosine permease complement(2544653..2545909) Escherichia coli 536 4191547 YP_670320.1 CDS ECP_2430 NC_008253.1 2545970 2546803 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2545970..2546803) Escherichia coli 536 4191548 YP_670321.1 CDS ECP_2431 NC_008253.1 2547051 2547815 D hypothetical protein 2547051..2547815 Escherichia coli 536 4191549 YP_670322.1 CDS ECP_2432 NC_008253.1 2547854 2548780 R LysR family transcriptional regulator complement(2547854..2548780) Escherichia coli 536 4191550 YP_670323.1 CDS ECP_2433 NC_008253.1 2548870 2549868 D hypothetical protein 2548870..2549868 Escherichia coli 536 4191551 YP_670324.1 CDS ECP_2434 NC_008253.1 2549865 2550083 R hypothetical protein complement(2549865..2550083) Escherichia coli 536 4191552 YP_670325.1 CDS ligA NC_008253.1 2550085 2552100 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2550085..2552100) Escherichia coli 536 4191553 YP_670326.1 CDS ECP_2436 NC_008253.1 2552171 2553169 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2552171..2553169) Escherichia coli 536 4191554 YP_670327.1 CDS ECP_2437 NC_008253.1 2553399 2554160 D role in sulfur assimilation; sulfate transport protein CysZ 2553399..2554160 Escherichia coli 536 4188511 YP_670328.1 CDS ECP_2438 NC_008253.1 2554345 2555316 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2554345..2555316 Escherichia coli 536 4188512 YP_670329.1 CDS ECP_2439 NC_008253.1 2555700 2555957 D phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) 2555700..2555957 Escherichia coli 536 4188513 YP_670330.1 CDS ECP_2440 NC_008253.1 2556002 2557729 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2556002..2557729 Escherichia coli 536 4188514 YP_670331.1 CDS ECP_2441 NC_008253.1 2557770 2558279 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; glucose-specific PTS system component 2557770..2558279 Escherichia coli 536 4188515 YP_670332.1 CDS pdxK NC_008253.1 2558322 2559173 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2558322..2559173) Escherichia coli 536 4188516 YP_670333.1 CDS ECP_2443 NC_008253.1 2559372 2559647 D hypothetical protein 2559372..2559647 Escherichia coli 536 4188517 YP_670334.1 CDS cysM NC_008253.1 2559650 2560561 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2559650..2560561) Escherichia coli 536 4188518 YP_670335.1 CDS ECP_2445 NC_008253.1 2560696 2561793 R sulfate/thiosulfate transporter subunit complement(2560696..2561793) Escherichia coli 536 4188519 YP_670336.1 CDS cysW NC_008253.1 2561783 2562658 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2561783..2562658) Escherichia coli 536 4188520 YP_670337.1 CDS ECP_2447 NC_008253.1 2562658 2563491 R sulfate/thiosulfate transporter subunit complement(2562658..2563491) Escherichia coli 536 4188521 YP_670338.1 CDS ECP_2448 NC_008253.1 2563491 2564507 R thiosulfate transporter subunit complement(2563491..2564507) Escherichia coli 536 4188522 YP_670339.1 CDS ECP_2449 NC_008253.1 2564665 2565456 R short chain dehydrogenase complement(2564665..2565456) Escherichia coli 536 4188523 YP_670340.1 CDS murQ NC_008253.1 2565736 2566632 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2565736..2566632 Escherichia coli 536 4188524 YP_670341.1 CDS murP NC_008253.1 2566636 2568060 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; N-acetylmuramic acid phosphotransfer permease 2566636..2568060 Escherichia coli 536 4188525 YP_670342.1 CDS ECP_2452 NC_008253.1 2568238 2569137 R iron-dependent peroxidase complement(2568238..2569137) Escherichia coli 536 4188526 YP_670343.1 CDS ECP_2453 NC_008253.1 2569233 2569808 R hypothetical protein complement(2569233..2569808) Escherichia coli 536 4188527 YP_670344.1 CDS ECP_2454 NC_008253.1 2569869 2570318 R hypothetical protein complement(2569869..2570318) Escherichia coli 536 4188528 YP_670345.1 CDS ECP_2455 NC_008253.1 2570305 2570730 R acetyltransferase complement(2570305..2570730) Escherichia coli 536 4188529 YP_670346.1 CDS ECP_2456 NC_008253.1 2570944 2571813 D N-acetylmuramoyl-L-alanine amidase 2570944..2571813 Escherichia coli 536 4188530 YP_670347.1 CDS ECP_2457 NC_008253.1 2571817 2572716 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2571817..2572716 Escherichia coli 536 4191706 YP_670348.1 CDS ECP_2458 NC_008253.1 2572722 2573774 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2572722..2573774) Escherichia coli 536 4191707 YP_670349.1 CDS ECP_2459 NC_008253.1 2573820 2574320 R ethanolamine utilization protein EutK complement(2573820..2574320) Escherichia coli 536 4191708 YP_670350.1 CDS ECP_2460 NC_008253.1 2574333 2574992 R ethanolamine utilization protein EutL complement(2574333..2574992) Escherichia coli 536 4191709 YP_670351.1 CDS ECP_2461 NC_008253.1 2575002 2575889 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2575002..2575889) Escherichia coli 536 4191710 YP_670352.1 CDS ECP_2462 NC_008253.1 2575910 2577271 R ethanolamine ammonia-lyase heavy chain complement(2575910..2577271) Escherichia coli 536 4191711 YP_670353.1 CDS eutA NC_008253.1 2577283 2578686 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2577283..2578686) Escherichia coli 536 4191712 YP_670354.1 CDS ECP_2464 NC_008253.1 2578683 2579909 R ethanolamine utilization protein EutH complement(2578683..2579909) Escherichia coli 536 4191713 YP_670355.1 CDS ECP_2465 NC_008253.1 2580226 2581413 R ethanolamine utilization protein EutG complement(2580226..2581413) Escherichia coli 536 4191714 YP_670356.1 CDS ECP_2466 NC_008253.1 2581403 2582239 R ethanolamine utilization protein EutJ complement(2581403..2582239) Escherichia coli 536 4191715 YP_670357.1 CDS ECP_2467 NC_008253.1 2582250 2583653 R ethanolamine utilization protein EutE complement(2582250..2583653) Escherichia coli 536 4191716 YP_670358.1 CDS ECP_2468 NC_008253.1 2583665 2583952 R ethanolamine utilization protein EutN complement(2583665..2583952) Escherichia coli 536 4191717 YP_670359.1 CDS ECP_2469 NC_008253.1 2584059 2584352 R ethanolamine utilization protein EutM complement(2584059..2584352) Escherichia coli 536 4191718 YP_670360.1 CDS eutD NC_008253.1 2584391 2585407 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2584391..2585407) Escherichia coli 536 4191719 YP_670361.1 CDS ECP_2471 NC_008253.1 2585404 2586207 R ethanolamine utilization cobalamin adenosyltransferase complement(2585404..2586207) Escherichia coli 536 4191720 YP_670362.1 CDS ECP_2472 NC_008253.1 2586204 2586905 R ethanolamine utilization protein EutQ complement(2586204..2586905) Escherichia coli 536 4191721 YP_670363.1 CDS ECP_2473 NC_008253.1 2586880 2587359 R ethanolamine utilization protein EutP complement(2586880..2587359) Escherichia coli 536 4191722 YP_670364.1 CDS ECP_2474 NC_008253.1 2587372 2587707 R ethanolamine utilization protein EutS complement(2587372..2587707) Escherichia coli 536 4191723 YP_670365.1 CDS ECP_2475 NC_008253.1 2588000 2590279 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2588000..2590279) Escherichia coli 536 4191724 YP_670366.1 CDS ECP_2476 NC_008253.1 2590568 2591518 D transaldolase A 2590568..2591518 Escherichia coli 536 4189371 YP_670367.1 CDS ECP_2477 NC_008253.1 2591538 2593541 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2591538..2593541 Escherichia coli 536 4189372 YP_670368.1 CDS ECP_2478 NC_008253.1 2593618 2594661 R hypothetical protein complement(2593618..2594661) Escherichia coli 536 4189373 YP_670369.1 CDS ECP_2479 NC_008253.1 2594787 2595362 R hypothetical protein complement(2594787..2595362) Escherichia coli 536 4189374 YP_670370.1 CDS ECP_2480 NC_008253.1 2595430 2597409 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(2595430..2597409) Escherichia coli 536 4189375 YP_670371.1 CDS ECP_2481 NC_008253.1 2597615 2599315 D nitrate/nitrite sensor protein NarQ 2597615..2599315 Escherichia coli 536 4189376 YP_670372.1 CDS ECP_2482 NC_008253.1 2599479 2602592 D aminoglycoside/multidrug efflux system 2599479..2602592 Escherichia coli 536 4189377 YP_670373.1 CDS ECP_2483 NC_008253.1 2602665 2602892 D hypothetical protein 2602665..2602892 Escherichia coli 536 4189378 YP_670374.1 CDS ECP_2484 NC_008253.1 2603131 2603487 D hypothetical protein 2603131..2603487 Escherichia coli 536 4189379 YP_670375.1 CDS ECP_2485 NC_008253.1 2603491 2604618 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2603491..2604618 Escherichia coli 536 4189380 YP_670376.1 CDS ECP_2486 NC_008253.1 2604646 2604846 D hypothetical protein 2604646..2604846 Escherichia coli 536 4189381 YP_670377.1 CDS ECP_2487 NC_008253.1 2604927 2605625 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(2604927..2605625) Escherichia coli 536 4189382 YP_670378.1 CDS ECP_2488 NC_008253.1 2605699 2607714 R hypothetical protein complement(2605699..2607714) Escherichia coli 536 4189383 YP_670379.1 CDS ECP_2489 NC_008253.1 2607729 2608592 R hypothetical protein complement(2607729..2608592) Escherichia coli 536 4189384 YP_670380.1 CDS ECP_2490 NC_008253.1 2608760 2609473 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2608760..2609473) Escherichia coli 536 4189385 YP_670381.1 CDS ECP_2491 NC_008253.1 2609686 2610720 R lipoprotein complement(2609686..2610720) Escherichia coli 536 4189386 YP_670382.1 CDS ECP_2492 NC_008253.1 2610737 2611615 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2610737..2611615) Escherichia coli 536 4189387 YP_670383.1 CDS gcvR NC_008253.1 2611761 2612333 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2611761..2612333 Escherichia coli 536 4189388 YP_670384.1 CDS bcp NC_008253.1 2612333 2612803 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2612333..2612803 Escherichia coli 536 4189389 YP_670385.1 CDS ECP_2495 NC_008253.1 2612902 2613963 R permease PerM complement(2612902..2613963) Escherichia coli 536 4189390 YP_670386.1 CDS ECP_2496 NC_008253.1 2614176 2615639 D hypothetical protein 2614176..2615639 Escherichia coli 536 4187681 YP_670387.1 CDS ECP_2497 NC_008253.1 2615660 2616019 D arsenate reductase 2615660..2616019 Escherichia coli 536 4187682 YP_670388.1 CDS ECP_2498 NC_008253.1 2616157 2616903 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2616157..2616903) Escherichia coli 536 4187683 YP_670389.1 CDS ECP_2499 NC_008253.1 2616953 2618242 R uracil transporter complement(2616953..2618242) Escherichia coli 536 4187684 YP_670390.1 CDS upp NC_008253.1 2618328 2618954 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2618328..2618954) Escherichia coli 536 4187685 YP_670391.1 CDS ECP_2501 NC_008253.1 2619279 2620316 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2619279..2620316 Escherichia coli 536 4187686 YP_670392.1 CDS purN NC_008253.1 2620316 2620954 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2620316..2620954 Escherichia coli 536 4187687 YP_670393.1 CDS ECP_2503 NC_008253.1 2621126 2623192 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2621126..2623192 Escherichia coli 536 4187688 YP_670394.1 CDS ECP_2504 NC_008253.1 2623197 2624738 D exopolyphosphatase 2623197..2624738 Escherichia coli 536 4187689 YP_670395.1 CDS ECP_2505 NC_008253.1 2624777 2627020 R hypothetical protein complement(2624777..2627020) Escherichia coli 536 4187690 YP_670397.1 CDS ECP_2507 NC_008253.1 2627877 2628392 D hypothetical protein 2627877..2628392 Escherichia coli 536 4187692 YP_670398.1 CDS ECP_2508 NC_008253.1 2628408 2628947 D hypothetical protein 2628408..2628947 Escherichia coli 536 4187693 YP_670399.1 CDS guaA NC_008253.1 2629041 2630618 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2629041..2630618) Escherichia coli 536 4187694 YP_670400.1 CDS ECP_2510 NC_008253.1 2630687 2632222 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2630687..2632222) Escherichia coli 536 4187695 YP_670401.1 CDS xseA NC_008253.1 2632315 2633691 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2632315..2633691 Escherichia coli 536 4187696 YP_670402.1 CDS ECP_2512 NC_008253.1 2633760 2641811 R outer membrane protein complement(2633760..2641811) Escherichia coli 536 4187697 YP_670403.1 CDS ECP_2513 NC_008253.1 2641932 2642909 R outer membrane protein complement(2641932..2642909) Escherichia coli 536 4187698 YP_670404.1 CDS ECP_2514 NC_008253.1 2642964 2645141 R intimin/invasin complement(2642964..2645141) Escherichia coli 536 4187699 YP_670405.1 CDS ECP_2515 NC_008253.1 2645350 2645565 R hypothetical protein complement(2645350..2645565) Escherichia coli 536 4190294 YP_670406.1 CDS engA NC_008253.1 2645628 2647100 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2645628..2647100) Escherichia coli 536 4190295 YP_670407.1 CDS ECP_2517 NC_008253.1 2647218 2648396 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2647218..2648396) Escherichia coli 536 4190296 YP_670408.1 CDS ECP_2518 NC_008253.1 2648407 2649027 R hypothetical protein complement(2648407..2649027) Escherichia coli 536 4190297 YP_670409.1 CDS hisS NC_008253.1 2649045 2650319 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2649045..2650319) Escherichia coli 536 4190298 YP_670410.1 CDS ispG NC_008253.1 2650430 2651548 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2650430..2651548) Escherichia coli 536 4190299 YP_670411.1 CDS ECP_2521 NC_008253.1 2651575 2652582 R hypothetical protein complement(2651575..2652582) Escherichia coli 536 4190300 YP_670412.1 CDS ECP_2522 NC_008253.1 2652867 2654021 R hypothetical protein complement(2652867..2654021) Escherichia coli 536 4190301 YP_670413.1 CDS ndk NC_008253.1 2654171 2654602 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2654171..2654602) Escherichia coli 536 4190302 YP_670414.1 CDS ECP_2524 NC_008253.1 2654751 2657063 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2654751..2657063) Escherichia coli 536 4190303 YP_670415.1 CDS ECP_2525 NC_008253.1 2657064 2662025 R lipoprotein YfhM complement(2657064..2662025) Escherichia coli 536 4190304 YP_670416.1 CDS sseA NC_008253.1 2662232 2663077 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2662232..2663077 Escherichia coli 536 4190305 YP_670417.1 CDS ECP_2527 NC_008253.1 2663570 2664355 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2663570..2664355) Escherichia coli 536 4190306 YP_670418.1 CDS ECP_2528 NC_008253.1 2664489 2665772 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase complement(2664489..2665772) Escherichia coli 536 4190307 YP_670419.1 CDS ECP_2529 NC_008253.1 2665831 2666031 R hypothetical protein complement(2665831..2666031) Escherichia coli 536 4190308 YP_670420.1 CDS ECP_2530 NC_008253.1 2666043 2666378 R (2Fe-2S) ferredoxin complement(2666043..2666378) Escherichia coli 536 4190309 YP_670421.1 CDS hscA NC_008253.1 2666380 2668230 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2666380..2668230) Escherichia coli 536 4190310 YP_670422.1 CDS hscB NC_008253.1 2668247 2668762 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2668247..2668762) Escherichia coli 536 4190311 YP_670423.1 CDS iscA NC_008253.1 2668858 2669181 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2668858..2669181) Escherichia coli 536 4190312 YP_670424.1 CDS ECP_2534 NC_008253.1 2669198 2669584 R scaffold protein complement(2669198..2669584) Escherichia coli 536 4190313 YP_670425.1 CDS ECP_2535 NC_008253.1 2669612 2670826 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2669612..2670826) Escherichia coli 536 4190741 YP_670426.1 CDS ECP_2536 NC_008253.1 2670938 2671426 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2670938..2671426) Escherichia coli 536 4190742 YP_670427.1 CDS ECP_2537 NC_008253.1 2671696 2672436 R tRNA/rRNA methyltransferase YfhQ complement(2671696..2672436) Escherichia coli 536 4190743 YP_670428.1 CDS ECP_2538 NC_008253.1 2672555 2673358 D inositol monophosphatase 2672555..2673358 Escherichia coli 536 4190744 YP_670429.1 CDS ECP_2539 NC_008253.1 2673503 2674357 D hypothetical protein 2673503..2674357 Escherichia coli 536 4190745 YP_670430.1 CDS ECP_2540 NC_008253.1 2674548 2675828 D stationary phase inducible protein CsiE 2674548..2675828 Escherichia coli 536 4190746 YP_670431.1 CDS ECP_2541 NC_008253.1 2675820 2676959 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(2675820..2676959) Escherichia coli 536 4190747 YP_670432.1 CDS ECP_2542 NC_008253.1 2677328 2677750 D hypothetical protein 2677328..2677750 Escherichia coli 536 4190748 YP_670433.1 CDS ECP_2543 NC_008253.1 2677825 2678346 D IS transposase 2677825..2678346 Escherichia coli 536 4190749 YP_670434.1 CDS ECP_2544 NC_008253.1 2678571 2679173 D IS transposase 2678571..2679173 Escherichia coli 536 4190750 YP_670435.1 CDS ECP_2545 NC_008253.1 2679346 2680218 R hypothetical protein complement(2679346..2680218) Escherichia coli 536 4190751 YP_670436.1 CDS ECP_2546 NC_008253.1 2680230 2681324 R zinc-type alcohol dehydrogenase-like protein YphC complement(2680230..2681324) Escherichia coli 536 4190752 YP_670437.1 CDS ECP_2547 NC_008253.1 2681357 2682355 R ABC transporter permease complement(2681357..2682355) Escherichia coli 536 4190753 YP_670438.1 CDS ECP_2548 NC_008253.1 2682380 2683891 R ABC transporter ATP-binding protein complement(2682380..2683891) Escherichia coli 536 4190754 YP_670439.1 CDS ECP_2549 NC_008253.1 2683914 2684897 R ABC transporter substrate-binding protein YphF complement(2683914..2684897) Escherichia coli 536 4190755 YP_670440.1 CDS ECP_2550 NC_008253.1 2684994 2688275 R hypothetical protein complement(2684994..2688275) Escherichia coli 536 4190756 YP_670441.1 CDS ECP_2551 NC_008253.1 2688393 2689586 D hypothetical protein 2688393..2689586 Escherichia coli 536 4190757 YP_670442.1 CDS glyA NC_008253.1 2689650 2690903 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2689650..2690903) Escherichia coli 536 4190758 YP_670443.1 CDS ECP_2553 NC_008253.1 2691007 2691183 D hypothetical protein 2691007..2691183 Escherichia coli 536 4190759 YP_670444.1 CDS ECP_2554 NC_008253.1 2691232 2692422 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2691232..2692422 Escherichia coli 536 4190760 YP_670445.1 CDS ECP_2555 NC_008253.1 2692467 2692805 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2692467..2692805) Escherichia coli 536 4190761 YP_670446.1 CDS ECP_2556 NC_008253.1 2692866 2694200 R hypothetical protein complement(2692866..2694200) Escherichia coli 536 4190762 YP_670447.1 CDS ECP_2557 NC_008253.1 2694190 2694903 R hypothetical protein complement(2694190..2694903) Escherichia coli 536 4190763 YP_670448.1 CDS ECP_2558 NC_008253.1 2695068 2696558 R sensor-like histidine kinase YfhK complement(2695068..2696558) Escherichia coli 536 4190764 YP_670449.1 CDS ECP_2559 NC_008253.1 2697071 2700958 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2697071..2700958) Escherichia coli 536 4190765 YP_670450.1 CDS ECP_2560 NC_008253.1 2701216 2702772 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2701216..2702772 Escherichia coli 536 4190766 YP_670451.1 CDS ECP_2561 NC_008253.1 2702769 2703305 R tRNA-specific adenosine deaminase complement(2702769..2703305) Escherichia coli 536 4190767 YP_670452.1 CDS ECP_2562 NC_008253.1 2703330 2703965 R hypothetical protein complement(2703330..2703965) Escherichia coli 536 4190768 YP_670453.1 CDS ECP_2563 NC_008253.1 2704174 2705022 D DNA-binding transcriptional regulator 2704174..2705022 Escherichia coli 536 4190769 YP_670454.1 CDS ECP_2564 NC_008253.1 2705078 2705338 D ferredoxin-like protein YfhL 2705078..2705338 Escherichia coli 536 4190770 YP_670455.1 CDS acpS NC_008253.1 2706033 2706413 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2706033..2706413) Escherichia coli 536 4190771 YP_670456.1 CDS ECP_2566 NC_008253.1 2706413 2707144 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2706413..2707144) Escherichia coli 536 4190772 YP_670457.1 CDS recO NC_008253.1 2707156 2707884 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2707156..2707884) Escherichia coli 536 4190773 YP_670458.1 CDS era NC_008253.1 2707896 2708801 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2707896..2708801) Escherichia coli 536 4190774 YP_670459.1 CDS rnc NC_008253.1 2708798 2709478 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2708798..2709478) Escherichia coli 536 4190775 YP_670460.1 CDS ECP_2570 NC_008253.1 2709745 2710719 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2709745..2710719) Escherichia coli 536 4190776 YP_670461.1 CDS ECP_2571 NC_008253.1 2710735 2712534 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2710735..2712534) Escherichia coli 536 4190777 YP_670462.1 CDS ECP_2572 NC_008253.1 2712732 2713211 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2712732..2713211) Escherichia coli 536 4190778 YP_670463.1 CDS rseB NC_008253.1 2713208 2714164 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2713208..2714164) Escherichia coli 536 4190779 YP_670464.1 CDS ECP_2574 NC_008253.1 2714164 2714814 R anti-RNA polymerase sigma factor SigE complement(2714164..2714814) Escherichia coli 536 4189219 YP_670465.1 CDS ECP_2575 NC_008253.1 2714847 2715422 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2714847..2715422) Escherichia coli 536 4189220 YP_670466.1 CDS ECP_2576 NC_008253.1 2715830 2717452 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2715830..2717452 Escherichia coli 536 4189221 YP_670467.1 CDS ECP_2577 NC_008253.1 2717437 2718174 R hypothetical protein complement(2717437..2718174) Escherichia coli 536 4189222 YP_670468.1 CDS ECP_2578 NC_008253.1 2718306 2719640 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2718306..2719640 Escherichia coli 536 4189223 YP_670469.1 CDS ECP_2579 NC_008253.1 2719673 2720554 R transcriptional regulator YfiE complement(2719673..2720554) Escherichia coli 536 4189224 YP_670470.1 CDS ECP_2580 NC_008253.1 2720657 2721244 D neutral amino-acid efflux protein 2720657..2721244 Escherichia coli 536 4189225 YP_670471.1 CDS ECP_2581 NC_008253.1 2721300 2721683 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2721300..2721683) Escherichia coli 536 4189226 YP_670472.1 CDS ECP_2582 NC_008253.1 2721988 2722677 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2721988..2722677 Escherichia coli 536 4189227 YP_670473.1 CDS ECP_2583 NC_008253.1 2722725 2723762 R methyltransferase complement(2722725..2723762) Escherichia coli 536 4189228 YP_670474.1 CDS ECP_2584 NC_008253.1 2723969 2724388 D thioredoxin 2 2723969..2724388 Escherichia coli 536 4189229 YP_670475.1 CDS ECP_2585 NC_008253.1 2724433 2725155 D hypothetical protein 2724433..2725155 Escherichia coli 536 4189230 YP_670476.1 CDS ECP_2586 NC_008253.1 2725187 2727847 D hypothetical protein 2725187..2727847 Escherichia coli 536 4189231 YP_670477.1 CDS pssA NC_008253.1 2727961 2729316 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2727961..2729316 Escherichia coli 536 4189232 YP_670478.1 CDS ECP_2588 NC_008253.1 2729362 2729685 D hypothetical protein 2729362..2729685 Escherichia coli 536 4189233 YP_670479.1 CDS ECP_2589 NC_008253.1 2729682 2731073 R alpha-ketoglutarate transporter complement(2729682..2731073) Escherichia coli 536 4189234 YP_670480.1 CDS ECP_2590 NC_008253.1 2731323 2731541 R transposase complement(2731323..2731541) Escherichia coli 536 4189235 YP_670481.1 CDS ECP_2591 NC_008253.1 2731637 2731969 R transposase complement(2731637..2731969) Escherichia coli 536 4189236 YP_670482.1 CDS ECP_2592 NC_008253.1 2731885 2732289 R transposase complement(2731885..2732289) Escherichia coli 536 4189237 YP_670483.1 CDS ECP_2593 NC_008253.1 2732533 2733135 R IS transposase complement(2732533..2733135) Escherichia coli 536 4189449 YP_670484.1 CDS ECP_2594 NC_008253.1 2733360 2733881 R IS transposase complement(2733360..2733881) Escherichia coli 536 4189450 YP_670485.1 CDS ECP_2595 NC_008253.1 2739465 2742038 R protein disaggregation chaperone complement(2739465..2742038) Escherichia coli 536 4189451 YP_670486.1 CDS ECP_2596 NC_008253.1 2742168 2742899 R hypothetical protein complement(2742168..2742899) Escherichia coli 536 4189452 YP_670487.1 CDS rluD NC_008253.1 2742896 2743876 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2742896..2743876) Escherichia coli 536 4189453 YP_670488.1 CDS ECP_2598 NC_008253.1 2744011 2744748 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2744011..2744748 Escherichia coli 536 4189454 YP_670489.1 CDS ECP_2599 NC_008253.1 2745018 2745359 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2745018..2745359 Escherichia coli 536 4189455 YP_670490.1 CDS pheA NC_008253.1 2745609 2746769 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2745609..2746769 Escherichia coli 536 4189456 YP_670491.1 CDS tyrA NC_008253.1 2746812 2747933 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2746812..2747933) Escherichia coli 536 4189457 YP_670492.1 CDS ECP_2602 NC_008253.1 2747944 2749014 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2747944..2749014) Escherichia coli 536 4189458 YP_670493.1 CDS ECP_2603 NC_008253.1 2749224 2749589 D hypothetical protein 2749224..2749589 Escherichia coli 536 4189459 YP_670494.1 CDS ECP_2604 NC_008253.1 2749738 2750256 D hypothetical protein 2749738..2750256 Escherichia coli 536 4189460 YP_670495.1 CDS ECP_2605 NC_008253.1 2750246 2751472 D hypothetical protein 2750246..2751472 Escherichia coli 536 4189461 YP_670496.1 CDS ECP_2606 NC_008253.1 2751488 2751970 D outer membrane lipoprotein 2751488..2751970 Escherichia coli 536 4189462 YP_670497.1 CDS rplS NC_008253.1 2752047 2752394 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2752047..2752394) Escherichia coli 536 4189463 YP_670498.1 CDS trmD NC_008253.1 2752436 2753203 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(2752436..2753203) Escherichia coli 536 4189464 YP_670499.1 CDS rimM NC_008253.1 2753234 2753782 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2753234..2753782) Escherichia coli 536 4189465 YP_670500.1 CDS rpsP NC_008253.1 2753801 2754049 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2753801..2754049) Escherichia coli 536 4189466 YP_670501.1 CDS ECP_2611 NC_008253.1 2754186 2755547 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2754186..2755547) Escherichia coli 536 4189467 YP_670502.1 CDS ECP_2612 NC_008253.1 2755639 2756505 D cytochrome C-type biogenesis protein 2755639..2756505 Escherichia coli 536 4189468 YP_670503.1 CDS ECP_2613 NC_008253.1 2756550 2757812 D hypothetical protein 2756550..2757812 Escherichia coli 536 4187622 YP_670504.1 CDS ECP_2614 NC_008253.1 2757867 2758460 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2757867..2758460) Escherichia coli 536 4187623 YP_670505.1 CDS ppnK NC_008253.1 2758583 2759461 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2758583..2759461 Escherichia coli 536 4187624 YP_670506.1 CDS ECP_2616 NC_008253.1 2759547 2761208 D recombination and repair protein 2759547..2761208 Escherichia coli 536 4187625 YP_670507.1 CDS ECP_2617 NC_008253.1 2761357 2761698 D hypothetical protein 2761357..2761698 Escherichia coli 536 4187626 YP_670508.1 CDS ECP_2618 NC_008253.1 2761761 2762051 R hypothetical protein complement(2761761..2762051) Escherichia coli 536 4187627 YP_670509.1 CDS ECP_2619 NC_008253.1 2762041 2762517 R hypothetical protein complement(2762041..2762517) Escherichia coli 536 4187628 YP_670510.1 CDS smpB NC_008253.1 2762649 2763131 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2762649..2763131 Escherichia coli 536 4187629 YP_670511.1 CDS ECP_2621 NC_008253.1 2763710 2763892 R hypothetical protein complement(2763710..2763892) Escherichia coli 536 4187630 YP_670512.1 CDS ECP_2622 NC_008253.1 2764391 2765368 D Gab-like protein; in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2764391..2765368 Escherichia coli 536 4187631 YP_670513.1 CDS ECP_2623 NC_008253.1 2765388 2766656 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2765388..2766656 Escherichia coli 536 4187632 YP_670514.1 CDS gabD NC_008253.1 2766679 2768127 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2766679..2768127 Escherichia coli 536 4187633 YP_670515.1 CDS ECP_2625 NC_008253.1 2768141 2769421 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2768141..2769421 Escherichia coli 536 4187634 YP_670516.1 CDS ECP_2626 NC_008253.1 2769659 2771059 D gamma-aminobutyrate transporter 2769659..2771059 Escherichia coli 536 4187635 YP_670517.1 CDS ECP_2627 NC_008253.1 2771080 2771742 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2771080..2771742 Escherichia coli 536 4187636 YP_670518.1 CDS ECP_2628 NC_008253.1 2771743 2772192 R LysM domain/BON superfamily protein complement(2771743..2772192) Escherichia coli 536 4187637 YP_670519.1 CDS ECP_2629 NC_008253.1 2772276 2772434 R hypothetical protein complement(2772276..2772434) Escherichia coli 536 4187638 YP_670520.1 CDS ECP_2630 NC_008253.1 2772617 2772916 D transcriptional regulator YgaV 2772617..2772916 Escherichia coli 536 4187639 YP_670521.1 CDS ECP_2631 NC_008253.1 2772926 2773450 D hypothetical protein 2772926..2773450 Escherichia coli 536 4187640 YP_670522.1 CDS ECP_2632 NC_008253.1 2773497 2773901 R DNA binding protein complement(2773497..2773901) Escherichia coli 536 4190800 YP_670523.1 CDS ECP_2633 NC_008253.1 2774568 2775017 D hypothetical protein 2774568..2775017 Escherichia coli 536 4190801 YP_670524.1 CDS ECP_2634 NC_008253.1 2775054 2775398 R hypothetical protein complement(2775054..2775398) Escherichia coli 536 4190802 YP_670525.1 CDS ECP_2635 NC_008253.1 2775550 2775879 D hypothetical protein 2775550..2775879 Escherichia coli 536 4190803 YP_670526.1 CDS ECP_2636 NC_008253.1 2775936 2777270 R GntR family transcriptional regulator complement(2775936..2777270) Escherichia coli 536 4190804 YP_670527.1 CDS ECP_2637 NC_008253.1 2777358 2777789 D hypothetical protein 2777358..2777789 Escherichia coli 536 4190805 YP_670528.1 CDS ECP_2638 NC_008253.1 2777998 2778243 D glutaredoxin-like protein 2777998..2778243 Escherichia coli 536 4190806 YP_670529.1 CDS nrdI NC_008253.1 2778240 2778650 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2778240..2778650 Escherichia coli 536 4190807 YP_670530.1 CDS ECP_2640 NC_008253.1 2778662 2780767 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2778662..2780767 Escherichia coli 536 4190808 YP_670531.1 CDS nrdF NC_008253.1 2780777 2781736 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2780777..2781736 Escherichia coli 536 4190809 YP_670532.1 CDS ECP_2642 NC_008253.1 2781881 2782102 D hypothetical protein 2781881..2782102 Escherichia coli 536 4190810 YP_670533.1 CDS ECP_2643 NC_008253.1 2782092 2783294 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2782092..2783294 Escherichia coli 536 4190811 YP_670534.1 CDS ECP_2644 NC_008253.1 2783287 2784351 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2783287..2784351 Escherichia coli 536 4190812 YP_670535.1 CDS proX NC_008253.1 2784409 2785401 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2784409..2785401 Escherichia coli 536 4190813 YP_670536.1 CDS ECP_2646 NC_008253.1 2785593 2786777 D transmembrane transport protein 2785593..2786777 Escherichia coli 536 4190814 YP_670537.1 CDS ECP_2647 NC_008253.1 2786901 2787638 D hypothetical protein 2786901..2787638 Escherichia coli 536 4190815 YP_670538.1 CDS ECP_2648 NC_008253.1 2787628 2787963 D hypothetical protein 2787628..2787963 Escherichia coli 536 4190816 YP_670539.1 CDS ECP_2649 NC_008253.1 2788054 2788584 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2788054..2788584 Escherichia coli 536 4190817 YP_670540.1 CDS ECP_2650 NC_008253.1 2788711 2789883 D multidrug resistance protein A 2788711..2789883 Escherichia coli 536 4190818 YP_670541.1 CDS ECP_2651 NC_008253.1 2789900 2791438 D multidrug resistance protein B 2789900..2791438 Escherichia coli 536 4190819 YP_670542.1 CDS ECP_2652 NC_008253.1 2791502 2792017 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(2791502..2792017) Escherichia coli 536 4190722 YP_670543.1 CDS ECP_2653 NC_008253.1 2792167 2793723 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(2792167..2793723) Escherichia coli 536 4190723 YP_670544.1 CDS ECP_2654 NC_008253.1 2793796 2794224 R hypothetical protein complement(2793796..2794224) Escherichia coli 536 4190724 YP_670545.1 CDS ECP_2655 NC_008253.1 2794221 2794787 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(2794221..2794787) Escherichia coli 536 4190725 YP_670546.1 CDS ECP_2656 NC_008253.1 2795842 2796027 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(2795842..2796027) Escherichia coli 536 4190726 YP_670547.1 CDS alaS NC_008253.1 2796262 2798892 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2796262..2798892) Escherichia coli 536 4190727 YP_670548.1 CDS recX NC_008253.1 2799021 2799521 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(2799021..2799521) Escherichia coli 536 4190728 YP_670549.1 CDS recA NC_008253.1 2799590 2800651 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2799590..2800651) Escherichia coli 536 4190729 YP_670550.1 CDS ECP_2660 NC_008253.1 2800731 2801228 R competence damage-inducible protein A complement(2800731..2801228) Escherichia coli 536 4190730 YP_670551.1 CDS ECP_2661 NC_008253.1 2801373 2802506 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(2801373..2802506) Escherichia coli 536 4190731 YP_670552.1 CDS ECP_2662 NC_008253.1 2802715 2803278 D PTS family, glucitol/sorbitol-specific enzyme IIC component,one of two IIC components 2802715..2803278 Escherichia coli 536 4190732 YP_670553.1 CDS ECP_2663 NC_008253.1 2803275 2804234 D PTS system, glucitol/sorbitol-specific IIBC component 2803275..2804234 Escherichia coli 536 4190733 YP_670554.1 CDS ECP_2664 NC_008253.1 2804245 2804616 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; glucitol/sorbitol-specific PTS system component IIA 2804245..2804616 Escherichia coli 536 4190734 YP_670555.1 CDS ECP_2665 NC_008253.1 2804620 2805399 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2804620..2805399 Escherichia coli 536 4190735 YP_670556.1 CDS ECP_2666 NC_008253.1 2805505 2805864 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2805505..2805864 Escherichia coli 536 4190736 YP_670557.1 CDS srlR NC_008253.1 2805931 2806704 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2805931..2806704 Escherichia coli 536 4190737 YP_670558.1 CDS gutQ NC_008253.1 2806697 2807662 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2806697..2807662 Escherichia coli 536 4190738 YP_670559.1 CDS ECP_2669 NC_008253.1 2807659 2809173 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(2807659..2809173) Escherichia coli 536 4190739 YP_670560.1 CDS ECP_2670 NC_008253.1 2809360 2810799 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2809360..2810799 Escherichia coli 536 4190740 YP_670561.1 CDS ECP_2671 NC_008253.1 2810796 2811929 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2810796..2811929 Escherichia coli 536 4189565 YP_670562.1 CDS ECP_2672 NC_008253.1 2812151 2814403 R hydrogenase maturation protein HypF complement(2812151..2814403) Escherichia coli 536 4189566 YP_670563.1 CDS ECP_2673 NC_008253.1 2814556 2815083 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(2814556..2815083) Escherichia coli 536 4189567 YP_670564.1 CDS ECP_2674 NC_008253.1 2815061 2815228 R hypothetical protein complement(2815061..2815228) Escherichia coli 536 4189568 YP_670565.1 CDS ECP_2675 NC_008253.1 2815232 2816245 R cryptic asc operon repressor complement(2815232..2816245) Escherichia coli 536 4189569 YP_670566.1 CDS ECP_2676 NC_008253.1 2816502 2817959 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; cellobiose/arbutin/salicin-specific PTS system components IIBC 2816502..2817959 Escherichia coli 536 4189570 YP_670567.1 CDS ECP_2677 NC_008253.1 2817968 2819392 D cryptic 6-phospho-beta-glucosidase 2817968..2819392 Escherichia coli 536 4189571 YP_670568.1 CDS ECP_2678 NC_008253.1 2819490 2819909 R HTH-type transcriptional regulator YgjM complement(2819490..2819909) Escherichia coli 536 4189572 YP_670569.1 CDS ECP_2679 NC_008253.1 2819935 2820102 R hypothetical protein complement(2819935..2820102) Escherichia coli 536 4189573 YP_670570.1 CDS hycI NC_008253.1 2820145 2820615 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(2820145..2820615) Escherichia coli 536 4189574 YP_670571.1 CDS ECP_2681 NC_008253.1 2820608 2821018 R formate hydrogenlyase maturation protein HYch complement(2820608..2821018) Escherichia coli 536 4189575 YP_670572.1 CDS ECP_2682 NC_008253.1 2821015 2821782 R formate hydrogenlyase-3 component G complement(2821015..2821782) Escherichia coli 536 4189576 YP_670573.1 CDS ECP_2683 NC_008253.1 2821782 2822324 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(2821782..2822324) Escherichia coli 536 4189577 YP_670574.1 CDS ECP_2684 NC_008253.1 2822334 2824043 R formate hydrogenase-3 component E complement(2822334..2824043) Escherichia coli 536 4189578 YP_670575.1 CDS ECP_2685 NC_008253.1 2824061 2824984 R formate hydrogenlyase subunit 4 complement(2824061..2824984) Escherichia coli 536 4189579 YP_670576.1 CDS ECP_2686 NC_008253.1 2824987 2826813 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(2824987..2826813) Escherichia coli 536 4189580 YP_670577.1 CDS ECP_2687 NC_008253.1 2826810 2827421 R formate hydrogenase-3 component B complement(2826810..2827421) Escherichia coli 536 4189581 YP_670578.1 CDS ECP_2688 NC_008253.1 2827546 2828007 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(2827546..2828007) Escherichia coli 536 4189582 YP_670579.1 CDS hypA NC_008253.1 2828219 2828569 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 2828219..2828569 Escherichia coli 536 4189583 YP_670580.1 CDS ECP_2690 NC_008253.1 2828573 2829445 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2828573..2829445 Escherichia coli 536 4189584 YP_670581.1 CDS ECP_2691 NC_008253.1 2829436 2829708 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2829436..2829708 Escherichia coli 536 4190424 YP_670582.1 CDS ECP_2692 NC_008253.1 2829708 2830829 D hydrogenase isoenzymes formation protein HYpd 2829708..2830829 Escherichia coli 536 4190425 YP_670583.1 CDS ECP_2693 NC_008253.1 2830826 2831836 D hydrogenase isoenzymes formation protein HypE 2830826..2831836 Escherichia coli 536 4190426 YP_670584.1 CDS ECP_2694 NC_008253.1 2831910 2833988 D formate hydrogenlyase transcriptional activator 2831910..2833988 Escherichia coli 536 4190427 YP_670585.1 CDS ECP_2695 NC_008253.1 2834033 2834461 D molybdenum-pterin-binding protein 2834033..2834461 Escherichia coli 536 4190428 YP_670586.1 CDS ECP_2696 NC_008253.1 2834500 2834844 R hypothetical protein complement(2834500..2834844) Escherichia coli 536 4190429 YP_670587.1 CDS ECP_2697 NC_008253.1 2834899 2835054 R hypothetical protein complement(2834899..2835054) Escherichia coli 536 4190430 YP_670588.1 CDS ECP_2698 NC_008253.1 2835907 2836404 D hypothetical protein 2835907..2836404 Escherichia coli 536 4190431 YP_670589.1 CDS ECP_2699 NC_008253.1 2836428 2837312 R hypothetical protein complement(2836428..2837312) Escherichia coli 536 4190432 YP_670590.1 CDS ECP_2700 NC_008253.1 2837717 2837917 D hypothetical protein 2837717..2837917 Escherichia coli 536 4190433 YP_670591.1 CDS ECP_2701 NC_008253.1 2838745 2839782 D transposase 2838745..2839782 Escherichia coli 536 4190434 YP_670592.1 CDS ECP_2702 NC_008253.1 2839884 2841254 R hypothetical protein complement(2839884..2841254) Escherichia coli 536 4190435 YP_670593.1 CDS ECP_2703 NC_008253.1 2841293 2842072 R transposase/IS protein complement(2841293..2842072) Escherichia coli 536 4190436 YP_670594.1 CDS ECP_2704 NC_008253.1 2842072 2842428 R transposase complement(2842072..2842428) Escherichia coli 536 4190437 YP_670595.1 CDS ECP_2705 NC_008253.1 2842488 2842790 D transposase 2842488..2842790 Escherichia coli 536 4190438 YP_670596.1 CDS ECP_2706 NC_008253.1 2842817 2843656 D transposase 2842817..2843656 Escherichia coli 536 4190439 YP_670597.1 CDS ECP_2707 NC_008253.1 2843660 2844346 R transposase complement(2843660..2844346) Escherichia coli 536 4190440 YP_670598.1 CDS ECP_2708 NC_008253.1 2844403 2844642 D hypothetical protein 2844403..2844642 Escherichia coli 536 4190441 YP_670599.1 CDS ECP_2709 NC_008253.1 2844856 2848707 R hypothetical protein complement(2844856..2848707) Escherichia coli 536 4190442 YP_670600.1 CDS ECP_2710 NC_008253.1 2848976 2849725 R hypothetical protein complement(2848976..2849725) Escherichia coli 536 4189982 YP_670601.1 CDS ECP_2711 NC_008253.1 2849946 2852507 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2849946..2852507 Escherichia coli 536 4189983 YP_670602.1 CDS ECP_2712 NC_008253.1 2852613 2853269 D serine/threonine-specific protein phosphatase 2 2852613..2853269 Escherichia coli 536 4189984 YP_670603.1 CDS ECP_2713 NC_008253.1 2853320 2854117 R DeoR family transcriptional regulator complement(2853320..2854117) Escherichia coli 536 4189985 YP_670604.1 CDS ECP_2714 NC_008253.1 2854283 2855191 D oxidoreductase YgbJ 2854283..2855191 Escherichia coli 536 4189986 YP_670605.1 CDS ECP_2715 NC_008253.1 2855188 2856450 D hypothetical protein 2855188..2856450 Escherichia coli 536 4189987 YP_670606.1 CDS ECP_2716 NC_008253.1 2856447 2857085 D aldolase 2856447..2857085 Escherichia coli 536 4189988 YP_670607.1 CDS ECP_2717 NC_008253.1 2857090 2857866 D endonuclease; hypothetical protein 2857090..2857866 Escherichia coli 536 4189989 YP_670608.1 CDS ECP_2718 NC_008253.1 2857955 2858560 D hypothetical protein 2857955..2858560 Escherichia coli 536 4189990 YP_670609.1 CDS ECP_2719 NC_008253.1 2858574 2859320 D hypothetical protein 2858574..2859320 Escherichia coli 536 4189991 YP_670610.1 CDS ECP_2720 NC_008253.1 2859463 2860506 R beta-lactamase-like protein complement(2859463..2860506) Escherichia coli 536 4189992 YP_670611.1 CDS ECP_2721 NC_008253.1 2860731 2861282 D hypothetical protein 2860731..2861282 Escherichia coli 536 4189993 YP_670612.1 CDS ECP_2722 NC_008253.1 2861460 2862452 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(2861460..2862452) Escherichia coli 536 4189994 YP_670613.1 CDS nlpD NC_008253.1 2862515 2863654 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(2862515..2863654) Escherichia coli 536 4189995 YP_670614.1 CDS ECP_2724 NC_008253.1 2863794 2863946 R protein-L-isoaspartate O-methyltransferase complement(2863794..2863946) Escherichia coli 536 4189996 YP_670615.1 CDS ECP_2725 NC_008253.1 2864085 2864420 R protein-L-isoaspartate O-methyltransferase complement(2864085..2864420) Escherichia coli 536 4189997 YP_670616.1 CDS surE NC_008253.1 2864414 2865175 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(2864414..2865175) Escherichia coli 536 4189998 YP_670617.1 CDS truD NC_008253.1 2865156 2866205 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(2865156..2866205) Escherichia coli 536 4189999 YP_670618.1 CDS ispF NC_008253.1 2866202 2866681 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(2866202..2866681) Escherichia coli 536 4190000 YP_670619.1 CDS ispD NC_008253.1 2866681 2867391 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(2866681..2867391) Escherichia coli 536 4190001 YP_670620.1 CDS ftsB NC_008253.1 2867410 2867721 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(2867410..2867721) Escherichia coli 536 4191555 YP_670621.1 CDS ECP_2731 NC_008253.1 2867914 2868237 R hypothetical protein complement(2867914..2868237) Escherichia coli 536 4191556 YP_670622.1 CDS ECP_2732 NC_008253.1 2868287 2868892 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(2868287..2868892) Escherichia coli 536 4191557 YP_670623.1 CDS cysN NC_008253.1 2868892 2870319 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(2868892..2870319) Escherichia coli 536 4191558 YP_670624.1 CDS ECP_2734 NC_008253.1 2870321 2871229 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2870321..2871229) Escherichia coli 536 4191559 YP_670625.1 CDS ECP_2735 NC_008253.1 2871481 2872518 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 2871481..2872518 Escherichia coli 536 4191560 YP_670626.1 CDS ECP_2736 NC_008253.1 2873061 2873795 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(2873061..2873795) Escherichia coli 536 4191561 YP_670627.1 CDS ECP_2737 NC_008253.1 2873869 2875581 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(2873869..2875581) Escherichia coli 536 4191562 YP_670628.1 CDS cysJ NC_008253.1 2875581 2877380 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(2875581..2877380) Escherichia coli 536 4191563 YP_670629.1 CDS ECP_2739 NC_008253.1 2877696 2878061 D 6-pyruvoyl tetrahydrobiopterin synthase 2877696..2878061 Escherichia coli 536 4191564 YP_670630.1 CDS ECP_2740 NC_008253.1 2878139 2879410 D electron transfer flavoprotein-quinone oxidoreductase YgcN 2878139..2879410 Escherichia coli 536 4191565 YP_670631.1 CDS ECP_2741 NC_008253.1 2879401 2879661 D ferredoxin-like protein YgcO 2879401..2879661 Escherichia coli 536 4191566 YP_670632.1 CDS ECP_2742 NC_008253.1 2879678 2880253 D anti-terminator regulatory protein YgcP 2879678..2880253 Escherichia coli 536 4191567 YP_670633.1 CDS ECP_2743 NC_008253.1 2880400 2881260 R electron transfer flavoprotein subunit YgcQ complement(2880400..2881260) Escherichia coli 536 4191568 YP_670634.1 CDS ECP_2744 NC_008253.1 2881257 2882051 R electron transfer flavoprotein subunit YgcR complement(2881257..2882051) Escherichia coli 536 4191569 YP_670635.1 CDS ECP_2745 NC_008253.1 2882014 2883351 R metabolite transport protein YgcS complement(2882014..2883351) Escherichia coli 536 4191570 YP_670636.1 CDS ECP_2746 NC_008253.1 2883445 2884899 R flavoprotein YgcU complement(2883445..2884899) Escherichia coli 536 4191571 YP_670637.1 CDS ECP_2747 NC_008253.1 2884969 2885754 R oxidoreductase YgcW complement(2884969..2885754) Escherichia coli 536 4191572 YP_670638.1 CDS ECP_2748 NC_008253.1 2886072 2887349 D hypothetical protein 2886072..2887349 Escherichia coli 536 4191573 YP_670639.1 CDS ECP_2749 NC_008253.1 2887376 2888854 D sugar kinase 2887376..2888854 Escherichia coli 536 4191648 YP_670640.1 CDS ECP_2750 NC_008253.1 2889019 2889939 D phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 2889019..2889939 Escherichia coli 536 4191649 YP_670641.1 CDS ECP_2751 NC_008253.1 2890107 2891624 D sucrose porin 2890107..2891624 Escherichia coli 536 4191650 YP_670642.1 CDS ECP_2752 NC_008253.1 2891685 2893055 D PTS system, sucrose-specific IIBC component 2891685..2893055 Escherichia coli 536 4191651 YP_670643.1 CDS ECP_2753 NC_008253.1 2893055 2894464 D sucrose-6-phosphate hydrolase 2893055..2894464 Escherichia coli 536 4191652 YP_670644.1 CDS ECP_2754 NC_008253.1 2894490 2895497 D sucrose operon repressor 2894490..2895497 Escherichia coli 536 4191653 YP_670645.1 CDS ECP_2755 NC_008253.1 2895582 2896253 R hypothetical protein complement(2895582..2896253) Escherichia coli 536 4191654 YP_670646.1 CDS ECP_2756 NC_008253.1 2896426 2897028 D hypothetical protein 2896426..2897028 Escherichia coli 536 4191655 YP_670647.1 CDS ECP_2757 NC_008253.1 2897042 2897950 D hypothetical protein 2897042..2897950 Escherichia coli 536 4191656 YP_670648.1 CDS ECP_2758 NC_008253.1 2897965 2899113 D hypothetical protein 2897965..2899113 Escherichia coli 536 4191657 YP_670649.1 CDS ECP_2759 NC_008253.1 2899119 2899991 D hypothetical protein 2899119..2899991 Escherichia coli 536 4191658 YP_670650.1 CDS eno NC_008253.1 2900051 2901349 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(2900051..2901349) Escherichia coli 536 4191659 YP_670651.1 CDS pyrG NC_008253.1 2901437 2903074 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(2901437..2903074) Escherichia coli 536 4191660 YP_670652.1 CDS mazG NC_008253.1 2903302 2904093 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase complement(2903302..2904093) Escherichia coli 536 4191661 YP_670653.1 CDS ECP_2763 NC_008253.1 2904165 2904500 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(2904165..2904500) Escherichia coli 536 4191662 YP_670654.1 CDS ECP_2764 NC_008253.1 2904500 2904748 R PemI-like protein 1; part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(2904500..2904748) Escherichia coli 536 4191663 YP_670655.1 CDS relA NC_008253.1 2904826 2907060 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(2904826..2907060) Escherichia coli 536 4191664 YP_670656.1 CDS rumA NC_008253.1 2907108 2908409 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(2907108..2908409) Escherichia coli 536 4191665 YP_670657.1 CDS ECP_2767 NC_008253.1 2908466 2911222 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 2908466..2911222 Escherichia coli 536 4191666 YP_670658.1 CDS ECP_2768 NC_008253.1 2911453 2912793 R glucarate dehydratase complement(2911453..2912793) Escherichia coli 536 4191667 YP_670659.1 CDS ECP_2769 NC_008253.1 2912814 2914154 R glucarate dehydratase complement(2912814..2914154) Escherichia coli 536 4189087 YP_670660.1 CDS ECP_2770 NC_008253.1 2914156 2915508 R glucarate transporter complement(2914156..2915508) Escherichia coli 536 4189088 YP_670661.1 CDS ECP_2771 NC_008253.1 2915942 2916391 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(2915942..2916391) Escherichia coli 536 4189089 YP_670662.1 CDS ECP_2772 NC_008253.1 2916409 2917191 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(2916409..2917191) Escherichia coli 536 4189090 YP_670663.1 CDS ECP_2773 NC_008253.1 2917191 2917520 R hypothetical protein complement(2917191..2917520) Escherichia coli 536 4189091 YP_670664.1 CDS ECP_2774 NC_008253.1 2917767 2917907 R hypothetical protein complement(2917767..2917907) Escherichia coli 536 4189092 YP_670665.1 CDS ECP_2775 NC_008253.1 2918142 2918687 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(2918142..2918687) Escherichia coli 536 4189093 YP_670666.1 CDS queF NC_008253.1 2918755 2919603 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 2918755..2919603 Escherichia coli 536 4189094 YP_670667.1 CDS ECP_2777 NC_008253.1 2919715 2921079 D hypothetical protein 2919715..2921079 Escherichia coli 536 4189095 YP_670668.1 CDS ECP_2778 NC_008253.1 2921636 2922925 D serine transporter 2921636..2922925 Escherichia coli 536 4189096 YP_670669.1 CDS xni NC_008253.1 2924463 2925218 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 2924463..2925218 Escherichia coli 536 4189099 YP_670670.1 CDS ECP_2782 NC_008253.1 2925323 2926474 R L-1,2-propanediol oxidoreductase complement(2925323..2926474) Escherichia coli 536 4189100 YP_670671.1 CDS ECP_2783 NC_008253.1 2926499 2927146 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(2926499..2927146) Escherichia coli 536 4189101 YP_670672.1 CDS ECP_2784 NC_008253.1 2927693 2929009 D L-fucose transporter 2927693..2929009 Escherichia coli 536 4189102 YP_670673.1 CDS fucI NC_008253.1 2929042 2930817 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2929042..2930817 Escherichia coli 536 4189103 YP_670674.1 CDS ECP_2786 NC_008253.1 2930896 2932344 D L-fuculokinase 2930896..2932344 Escherichia coli 536 4187397 YP_670675.1 CDS ECP_2787 NC_008253.1 2932346 2932768 D fucose operon FucU protein 2932346..2932768 Escherichia coli 536 4187398 YP_670676.1 CDS ECP_2788 NC_008253.1 2932944 2933558 D DNA-binding transcriptional activator 2932944..2933558 Escherichia coli 536 4187399 YP_670677.1 CDS ECP_2789 NC_008253.1 2933602 2934702 R RNA 2'-O-ribose methyltransferase complement(2933602..2934702) Escherichia coli 536 4187400 YP_670678.1 CDS ECP_2790 NC_008253.1 2934695 2935090 R hypothetical protein complement(2934695..2935090) Escherichia coli 536 4187401 YP_670679.1 CDS ECP_2791 NC_008253.1 2935109 2936026 R regulatory protein for glycine cleavage pathway; Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(2935109..2936026) Escherichia coli 536 4187402 YP_670680.1 CDS ECP_2792 NC_008253.1 2936377 2936604 R lipoprotein complement(2936377..2936604) Escherichia coli 536 4187403 YP_670681.1 CDS ECP_2793 NC_008253.1 2936796 2938001 D cysteine sulfinate desulfinase 2936796..2938001 Escherichia coli 536 4187404 YP_670682.1 CDS ECP_2794 NC_008253.1 2938001 2938444 D hypothetical protein 2938001..2938444 Escherichia coli 536 4187405 YP_670683.1 CDS ECP_2795 NC_008253.1 2938495 2939301 R hypothetical protein complement(2938495..2939301) Escherichia coli 536 4187406 YP_670684.2 CDS mltA NC_008253.1 2939378 2940475 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(2939378..2940475) Escherichia coli 536 4187407 YP_670685.1 CDS ECP_2800 NC_008253.1 2941612 2942112 D hypothetical protein 2941612..2942112 Escherichia coli 536 4187411 YP_670686.1 CDS ECP_2801 NC_008253.1 2942171 2943709 D hypothetical protein 2942171..2943709 Escherichia coli 536 4187412 YP_670687.1 CDS ECP_2802 NC_008253.1 2943727 2945064 D hypothetical protein 2943727..2945064 Escherichia coli 536 4187413 YP_670688.1 CDS ECP_2803 NC_008253.1 2945061 2945726 D hypothetical protein 2945061..2945726 Escherichia coli 536 4187414 YP_670689.1 CDS ECP_2804 NC_008253.1 2945739 2947391 D OmpA family membrane protein 2945739..2947391 Escherichia coli 536 4187415 YP_670690.1 CDS ECP_2805 NC_008253.1 2947449 2947940 D hemolysin-coregulated protein Hcp 2947449..2947940 Escherichia coli 536 4187416 YP_670691.1 CDS ECP_2806 NC_008253.1 2948132 2950768 D CLPA/B-type chaperone protein 2948132..2950768 Escherichia coli 536 4187417 YP_670692.1 CDS ECP_2807 NC_008253.1 2950780 2953269 D VGR-related protein 2950780..2953269 Escherichia coli 536 4187418 YP_670693.1 CDS ECP_2808 NC_008253.1 2953335 2954153 D transmembrane protein 2953335..2954153 Escherichia coli 536 4187419 YP_670694.1 CDS ECP_2809 NC_008253.1 2954167 2954760 D hypothetical protein 2954167..2954760 Escherichia coli 536 4187420 YP_670695.1 CDS ECP_2810 NC_008253.1 2954805 2957324 D VGR-related protein 2954805..2957324 Escherichia coli 536 4187421 YP_670696.1 CDS ECP_2811 NC_008253.1 2957317 2958105 D hypothetical protein 2957317..2958105 Escherichia coli 536 4187422 YP_670697.1 CDS ECP_2812 NC_008253.1 2958190 2959110 D hypothetical protein 2958190..2959110 Escherichia coli 536 4187423 YP_670698.1 CDS ECP_2813 NC_008253.1 2959367 2960581 D hypothetical protein 2959367..2960581 Escherichia coli 536 4187424 YP_670699.1 CDS ECP_2814 NC_008253.1 2960533 2963964 D hypothetical protein 2960533..2963964 Escherichia coli 536 4187425 YP_670700.1 CDS ECP_2815 NC_008253.1 2963930 2965567 D hypothetical protein 2963930..2965567 Escherichia coli 536 4187426 YP_670701.1 CDS ECP_2816 NC_008253.1 2965573 2967003 D hypothetical protein 2965573..2967003 Escherichia coli 536 4187427 YP_670702.1 CDS ECP_2817 NC_008253.1 2966996 2967400 D hypothetical protein 2966996..2967400 Escherichia coli 536 4187428 YP_670703.1 CDS ECP_2818 NC_008253.1 2967475 2967792 D hypothetical protein 2967475..2967792 Escherichia coli 536 4187429 YP_670704.1 CDS ECP_2819 NC_008253.1 2967749 2969236 D hypothetical protein 2967749..2969236 Escherichia coli 536 4187430 YP_670705.1 CDS ECP_2820 NC_008253.1 2969200 2970279 D hypothetical protein 2969200..2970279 Escherichia coli 536 4187431 YP_670706.1 CDS ECP_2821 NC_008253.1 2970260 2970796 D hypothetical protein 2970260..2970796 Escherichia coli 536 4187432 YP_670707.1 CDS ECP_2822 NC_008253.1 2970800 2971228 D hypothetical protein 2970800..2971228 Escherichia coli 536 4187584 YP_670708.1 CDS ECP_2823 NC_008253.1 2971228 2972604 D hypothetical protein 2971228..2972604 Escherichia coli 536 4187585 YP_670709.1 CDS ECP_2824 NC_008253.1 2972904 2973851 R 2-hydroxyacid dehydrogenase complement(2972904..2973851) Escherichia coli 536 4187586 YP_670710.1 CDS ECP_2825 NC_008253.1 2973923 2974519 R posphosugar isomerase complement(2973923..2974519) Escherichia coli 536 4187587 YP_670711.1 CDS ECP_2826 NC_008253.1 2974522 2975697 R aminotransferase complement(2974522..2975697) Escherichia coli 536 4187588 YP_670712.1 CDS ECP_2827 NC_008253.1 2975697 2977226 R PTS system, maltose and glucose-specific IIABC component complement(2975697..2977226) Escherichia coli 536 4187589 YP_670713.1 CDS ECP_2828 NC_008253.1 2977309 2978133 R transcriptional antiterminator protein complement(2977309..2978133) Escherichia coli 536 4187590 YP_670714.1 CDS ECP_2829 NC_008253.1 2978391 2979644 R amidase complement(2978391..2979644) Escherichia coli 536 4187591 YP_670715.1 CDS ECP_2830 NC_008253.1 2979876 2981207 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 2979876..2981207 Escherichia coli 536 4187592 YP_670716.1 CDS recD NC_008253.1 2981289 2983115 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(2981289..2983115) Escherichia coli 536 4187593 YP_670717.1 CDS recB NC_008253.1 2983115 2986657 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(2983115..2986657) Escherichia coli 536 4187594 YP_670718.1 CDS ECP_2833 NC_008253.1 2986650 2989538 R protease III complement(2986650..2989538) Escherichia coli 536 4187595 YP_670719.1 CDS recC NC_008253.1 2989714 2993082 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(2989714..2993082) Escherichia coli 536 4187596 YP_670720.1 CDS ECP_2835 NC_008253.1 2993095 2993418 R hypothetical protein complement(2993095..2993418) Escherichia coli 536 4187597 YP_670721.1 CDS ECP_2836 NC_008253.1 2993403 2993810 R hypothetical protein complement(2993403..2993810) Escherichia coli 536 4187598 YP_670722.1 CDS ECP_2837 NC_008253.1 2993807 2994610 R hypothetical protein complement(2993807..2994610) Escherichia coli 536 4187599 YP_670723.1 CDS ECP_2838 NC_008253.1 2994361 2994831 R hypothetical protein complement(2994361..2994831) Escherichia coli 536 4187600 YP_670725.1 CDS thyA NC_008253.1 2995016 2995810 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(2995016..2995810) Escherichia coli 536 4187602 YP_670726.1 CDS ECP_2841 NC_008253.1 2995817 2996692 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(2995817..2996692) Escherichia coli 536 4188093 YP_670727.1 CDS ECP_2842 NC_008253.1 2996843 2999089 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(2996843..2999089) Escherichia coli 536 4188094 YP_670728.1 CDS ECP_2843 NC_008253.1 2999102 2999632 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(2999102..2999632) Escherichia coli 536 4188095 YP_670729.1 CDS ECP_2844 NC_008253.1 3000317 3001006 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3000317..3001006 Escherichia coli 536 4188096 YP_670730.1 CDS ECP_2845 NC_008253.1 3001075 3001788 D integral membrane transport protein 3001075..3001788 Escherichia coli 536 4188097 YP_670731.1 CDS ECP_2846 NC_008253.1 3001926 3002144 D lipoprotein 3001926..3002144 Escherichia coli 536 4188098 YP_670732.1 CDS tas NC_008253.1 3002252 3003292 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3002252..3003292 Escherichia coli 536 4188099 YP_670733.1 CDS ECP_2848 NC_008253.1 3003324 3004517 R lysophospholipid transporter LplT complement(3003324..3004517) Escherichia coli 536 4188100 YP_670734.1 CDS ECP_2849 NC_008253.1 3004510 3006669 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3004510..3006669) Escherichia coli 536 4188101 YP_670735.1 CDS ECP_2850 NC_008253.1 3007255 3008286 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3007255..3008286 Escherichia coli 536 4188102 YP_670736.1 CDS ECP_2851 NC_008253.1 3008293 3009555 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3008293..3009555) Escherichia coli 536 4188103 YP_670737.1 CDS ECP_2852 NC_008253.1 3009677 3010612 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3009677..3010612 Escherichia coli 536 4188104 YP_670738.1 CDS ECP_2853 NC_008253.1 3010599 3011291 R racemase complement(3010599..3011291) Escherichia coli 536 4188105 YP_670739.1 CDS ECP_2854 NC_008253.1 3011420 3012838 R arabinose-proton symporter complement(3011420..3012838) Escherichia coli 536 4188106 YP_670740.1 CDS ECP_2855 NC_008253.1 3013153 3013914 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3013153..3013914) Escherichia coli 536 4188107 YP_670741.1 CDS ECP_2856 NC_008253.1 3013944 3014780 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3013944..3014780) Escherichia coli 536 4188108 YP_670742.1 CDS ECP_2857 NC_008253.1 3015067 3016248 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3015067..3016248) Escherichia coli 536 4188109 YP_670743.1 CDS ECP_2858 NC_008253.1 3016503 3017732 D transporter 3016503..3017732 Escherichia coli 536 4188110 YP_670744.1 CDS ECP_2859 NC_008253.1 3018200 3018955 R metalloendopeptidase complement(3018200..3018955) Escherichia coli 536 4188111 YP_670745.1 CDS ECP_2860 NC_008253.1 3019369 3021666 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3019369..3021666 Escherichia coli 536 4188112 YP_670746.1 CDS ECP_2861 NC_008253.1 3021677 3022555 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3021677..3022555 Escherichia coli 536 4189124 YP_670747.1 CDS ECP_2862 NC_008253.1 3022552 3023031 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3022552..3023031 Escherichia coli 536 4189125 YP_670748.1 CDS ECP_2863 NC_008253.1 3023071 3024849 R sigma-54-dependent transcriptional regulator YgeV complement(3023071..3024849) Escherichia coli 536 4189126 YP_670749.1 CDS ECP_2864 NC_008253.1 3025325 3026515 D aspartate/ornithine carbamoyltransferase 3025325..3026515 Escherichia coli 536 4189127 YP_670750.1 CDS ECP_2865 NC_008253.1 3026573 3027769 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3026573..3027769 Escherichia coli 536 4189128 YP_670751.1 CDS ECP_2866 NC_008253.1 3027827 3029038 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3027827..3029038 Escherichia coli 536 4189129 YP_670752.1 CDS ECP_2867 NC_008253.1 3029091 3030476 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3029091..3030476 Escherichia coli 536 4189130 YP_670753.1 CDS ECP_2868 NC_008253.1 3030524 3031456 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3030524..3031456 Escherichia coli 536 4189131 YP_670754.1 CDS ECP_2869 NC_008253.1 3031497 3033122 R hypothetical protein complement(3031497..3033122) Escherichia coli 536 4189132 YP_670755.1 CDS ECP_2870 NC_008253.1 3033170 3033721 R hypothetical protein complement(3033170..3033721) Escherichia coli 536 4189133 YP_670756.1 CDS ECP_2871 NC_008253.1 3034092 3034622 D hypothetical protein 3034092..3034622 Escherichia coli 536 4189134 YP_670757.1 CDS ECP_2872 NC_008253.1 3034944 3038042 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3034944..3038042 Escherichia coli 536 4189135 YP_670758.1 CDS ECP_2873 NC_008253.1 3038045 3039373 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3038045..3039373 Escherichia coli 536 4189136 YP_670759.1 CDS ECP_2874 NC_008253.1 3039424 3040203 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3039424..3040203 Escherichia coli 536 4189137 YP_670760.1 CDS ECP_2875 NC_008253.1 3040200 3043070 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3040200..3043070 Escherichia coli 536 4189138 YP_670761.1 CDS ECP_2876 NC_008253.1 3043235 3044635 D transmembrane transport protein 3043235..3044635 Escherichia coli 536 4189139 YP_670762.1 CDS ECP_2877 NC_008253.1 3044653 3045969 D Catalyzes the deamination of guanine; guanine deaminase 3044653..3045969 Escherichia coli 536 4189140 YP_670763.1 CDS ECP_2878 NC_008253.1 3046005 3047372 D hypothetical protein 3046005..3047372 Escherichia coli 536 4189141 YP_670764.1 CDS ECP_2879 NC_008253.1 3047408 3047896 R electron transport protein YgfS complement(3047408..3047896) Escherichia coli 536 4189142 YP_670765.1 CDS ECP_2880 NC_008253.1 3047896 3049815 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3047896..3049815) Escherichia coli 536 4188863 YP_670766.1 CDS ECP_2881 NC_008253.1 3050251 3051699 D purine permease YgfU 3050251..3051699 Escherichia coli 536 4188864 YP_670767.1 CDS ECP_2882 NC_008253.1 3051949 3052497 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3051949..3052497 Escherichia coli 536 4188865 YP_670768.1 CDS lysS NC_008253.1 3052540 3054057 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3052540..3054057) Escherichia coli 536 4188866 YP_670769.1 CDS ECP_2884 NC_008253.1 3054067 3054948 R peptide chain release factor 2 complement(3054067..3054948) Escherichia coli 536 4188867 YP_670770.1 CDS ECP_2885 NC_008253.1 3055256 3056989 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3055256..3056989) Escherichia coli 536 4188868 YP_670771.1 CDS ECP_2886 NC_008253.1 3056995 3057705 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3056995..3057705) Escherichia coli 536 4188869 YP_670772.1 CDS xerD NC_008253.1 3057730 3058626 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3057730..3058626) Escherichia coli 536 4188870 YP_670773.1 CDS ECP_2888 NC_008253.1 3058738 3059259 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3058738..3059259 Escherichia coli 536 4188871 YP_670774.1 CDS ECP_2889 NC_008253.1 3059299 3059706 R hypothetical protein complement(3059299..3059706) Escherichia coli 536 4188872 YP_670775.1 CDS ECP_2890 NC_008253.1 3059687 3059953 R hypothetical protein complement(3059687..3059953) Escherichia coli 536 4188873 YP_670776.1 CDS ECP_2891 NC_008253.1 3059937 3060119 D hypothetical protein 3059937..3060119 Escherichia coli 536 4188874 YP_670777.1 CDS ECP_2892 NC_008253.1 3060196 3061176 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3060196..3061176 Escherichia coli 536 4188875 YP_670778.1 CDS ECP_2893 NC_008253.1 3061253 3061912 R hemolysin ( membrane protein) complement(3061253..3061912) Escherichia coli 536 4188876 YP_670779.1 CDS ECP_2894 NC_008253.1 3062076 3062387 R hypothetical protein complement(3062076..3062387) Escherichia coli 536 4188877 YP_670780.1 CDS ECP_2895 NC_008253.1 3062432 3063865 D 6-phospho-beta-glucosidase 3062432..3063865 Escherichia coli 536 4188878 YP_670781.1 CDS ECP_2896 NC_008253.1 3064031 3066904 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3064031..3066904) Escherichia coli 536 4188879 YP_670782.1 CDS ECP_2897 NC_008253.1 3067022 3067411 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3067022..3067411) Escherichia coli 536 4188880 YP_670783.2 CDS gcvT NC_008253.1 3067435 3068529 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3067435..3068529) Escherichia coli 536 4188881 YP_670784.1 CDS ECP_2899 NC_008253.1 3068977 3070179 R hypothetical protein complement(3068977..3070179) Escherichia coli 536 4188882 YP_670785.1 CDS ECP_2900 NC_008253.1 3070202 3071380 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3070202..3071380) Escherichia coli 536 4190944 YP_670786.1 CDS ECP_2901 NC_008253.1 3071377 3072702 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3071377..3072702) Escherichia coli 536 4190945 YP_670787.2 CDS ECP_2902 NC_008253.1 3072728 3073306 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3072728..3073306) Escherichia coli 536 4190946 YP_670788.1 CDS ECP_2903 NC_008253.1 3073474 3073803 D Z-ring-associated protein 3073474..3073803 Escherichia coli 536 4190947 YP_670789.2 CDS ECP_2904 NC_008253.1 3074103 3074651 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3074103..3074651 Escherichia coli 536 4190948 YP_670790.1 CDS ECP_2905 NC_008253.1 3075041 3076273 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3075041..3076273) Escherichia coli 536 4190949 YP_670791.1 CDS ECP_2906 NC_008253.1 3076529 3077224 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3076529..3077224) Escherichia coli 536 4190950 YP_670792.1 CDS ECP_2907 NC_008253.1 3077244 3077522 R hypothetical protein complement(3077244..3077522) Escherichia coli 536 4190951 YP_670793.1 CDS ECP_2908 NC_008253.1 3077615 3078508 D oriC replication inhibitor; specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3077615..3078508 Escherichia coli 536 4190952 YP_670794.1 CDS ECP_2909 NC_008253.1 3078711 3079805 D hypothetical protein 3078711..3079805 Escherichia coli 536 4190953 YP_670795.1 CDS ECP_2910 NC_008253.1 3079802 3080698 R transcriptional regulator YgfI complement(3079802..3080698) Escherichia coli 536 4190954 YP_670796.1 CDS ECP_2911 NC_008253.1 3080856 3081548 R hypothetical protein complement(3080856..3081548) Escherichia coli 536 4190955 YP_670797.1 CDS ECP_2912 NC_008253.1 3081689 3082324 R Involved in the export of arginine; arginine exporter protein complement(3081689..3082324) Escherichia coli 536 4190956 YP_670798.1 CDS ECP_2913 NC_008253.1 3082463 3083323 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3082463..3083323) Escherichia coli 536 4190957 YP_670799.1 CDS ECP_2914 NC_008253.1 3083346 3084611 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3083346..3084611) Escherichia coli 536 4190958 YP_670800.1 CDS pgk NC_008253.1 3084826 3085989 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3084826..3085989) Escherichia coli 536 4190959 YP_670801.1 CDS ECP_2916 NC_008253.1 3086039 3087058 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3086039..3087058) Escherichia coli 536 4190960 YP_670802.1 CDS ECP_2917 NC_008253.1 3087430 3087858 D hypothetical protein 3087430..3087858 Escherichia coli 536 4190961 YP_670803.1 CDS ECP_2918 NC_008253.1 3087885 3088463 D inner membrane protein 3087885..3088463 Escherichia coli 536 4190962 YP_670804.1 CDS ECP_2919 NC_008253.1 3088464 3089171 D ABC transporter permease 3088464..3089171 Escherichia coli 536 4188733 YP_670805.1 CDS ECP_2920 NC_008253.1 3089159 3089836 D ABC transporter ATP-binding protein 3089159..3089836 Escherichia coli 536 4188734 YP_670806.1 CDS ECP_2921 NC_008253.1 3089830 3090507 D ABC transporter ATP-binding protein 3089830..3090507 Escherichia coli 536 4188735 YP_670807.1 CDS frcK NC_008253.1 3090479 3091192 R fructose transport system kinase complement(3090479..3091192) Escherichia coli 536 4188736 YP_670808.1 CDS ECP_2923 NC_008253.1 3091189 3091698 R DNA-binding transcriptional regulator complement(3091189..3091698) Escherichia coli 536 4188737 YP_670809.1 CDS ECP_2924 NC_008253.1 3091847 3092035 R hypothetical protein complement(3091847..3092035) Escherichia coli 536 4188738 YP_670810.1 CDS ECP_2925 NC_008253.1 3092032 3093309 R hypothetical protein complement(3092032..3093309) Escherichia coli 536 4188739 YP_670811.1 CDS ECP_2926 NC_008253.1 3093324 3094712 R PTS system, mannitol (cryptic)-specific IIBC component complement(3093324..3094712) Escherichia coli 536 4188740 YP_670812.1 CDS cmtB NC_008253.1 3094740 3095183 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3094740..3095183) Escherichia coli 536 4188741 YP_670813.1 CDS ECP_2928 NC_008253.1 3095561 3096469 D SPFH domain-containing protein 3095561..3096469 Escherichia coli 536 4188742 YP_670814.1 CDS ECP_2929 NC_008253.1 3096689 3098680 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3096689..3098680) Escherichia coli 536 4188743 YP_670815.1 CDS ECP_2930 NC_008253.1 3098832 3099716 D metalloprotease YggG 3098832..3099716 Escherichia coli 536 4188744 YP_670816.1 CDS ECP_2931 NC_008253.1 3099807 3100727 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3099807..3100727) Escherichia coli 536 4188745 YP_670817.1 CDS ECP_2932 NC_008253.1 3100863 3101594 R hypothetical protein complement(3100863..3101594) Escherichia coli 536 4188746 YP_670818.1 CDS ECP_2933 NC_008253.1 3101740 3103716 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3101740..3103716) Escherichia coli 536 4188747 YP_670819.1 CDS ECP_2934 NC_008253.1 3104204 3104455 R hypothetical protein complement(3104204..3104455) Escherichia coli 536 4188748 YP_670820.1 CDS ECP_2935 NC_008253.1 3104511 3105665 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3104511..3105665 Escherichia coli 536 4188749 YP_670821.1 CDS ECP_2936 NC_008253.1 3105728 3105943 D hypothetical protein 3105728..3105943 Escherichia coli 536 4188750 YP_670822.1 CDS ECP_2937 NC_008253.1 3106102 3107496 D galactose-proton symporter 3106102..3107496 Escherichia coli 536 4188751 YP_670823.1 CDS ECP_2938 NC_008253.1 3107519 3108070 D hypothetical protein 3107519..3108070 Escherichia coli 536 4188752 YP_670824.1 CDS ECP_2939 NC_008253.1 3108165 3108872 D endonuclease I 3108165..3108872 Escherichia coli 536 4188336 YP_670825.1 CDS ECP_2940 NC_008253.1 3108952 3109683 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3108952..3109683 Escherichia coli 536 4188337 YP_670826.1 CDS ECP_2941 NC_008253.1 3109696 3110646 D The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3109696..3110646 Escherichia coli 536 4188338 YP_670827.1 CDS ECP_2942 NC_008253.1 3110755 3111318 D hypothetical protein 3110755..3111318 Escherichia coli 536 4188339 YP_670828.1 CDS ECP_2943 NC_008253.1 3111318 3111734 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3111318..3111734 Escherichia coli 536 4188340 YP_670829.1 CDS ECP_2944 NC_008253.1 3111908 3112888 R hypothetical protein complement(3111908..3112888) Escherichia coli 536 4188341 YP_670830.1 CDS ECP_2945 NC_008253.1 3112906 3113610 D hypothetical protein 3112906..3113610 Escherichia coli 536 4188342 YP_670831.1 CDS ECP_2946 NC_008253.1 3113628 3114194 D membrane protein YggT 3113628..3114194 Escherichia coli 536 4188343 YP_670832.1 CDS ECP_2947 NC_008253.1 3114191 3114481 D hypothetical protein 3114191..3114481 Escherichia coli 536 4188344 YP_670833.1 CDS ECP_2948 NC_008253.1 3114489 3115082 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3114489..3115082 Escherichia coli 536 4188345 YP_670834.1 CDS ECP_2949 NC_008253.1 3115075 3116211 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3115075..3116211 Escherichia coli 536 4188346 YP_670835.1 CDS ECP_2950 NC_008253.1 3116276 3117283 R hypothetical protein complement(3116276..3117283) Escherichia coli 536 4188347 YP_670836.1 CDS ansB NC_008253.1 3117400 3118446 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3117400..3118446) Escherichia coli 536 4188348 YP_670837.1 CDS ECP_2952 NC_008253.1 3118622 3119341 R hypothetical protein complement(3118622..3119341) Escherichia coli 536 4188349 YP_670838.1 CDS ECP_2953 NC_008253.1 3119525 3119851 R hypothetical protein complement(3119525..3119851) Escherichia coli 536 4188350 YP_670839.1 CDS trmB NC_008253.1 3119851 3120570 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3119851..3120570) Escherichia coli 536 4188351 YP_670840.1 CDS ECP_2955 NC_008253.1 3120731 3121783 D adenine DNA glycosylase 3120731..3121783 Escherichia coli 536 4188352 YP_670841.1 CDS ECP_2956 NC_008253.1 3121811 3122086 D hypothetical protein 3121811..3122086 Escherichia coli 536 4188353 YP_670842.1 CDS mltC NC_008253.1 3122148 3123230 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3122148..3123230 Escherichia coli 536 4188354 YP_670843.1 CDS ECP_2958 NC_008253.1 3123432 3124688 D nucleoside permease NupG 3123432..3124688 Escherichia coli 536 4191093 YP_670844.1 CDS ECP_2959 NC_008253.1 3124737 3126872 R ornithine decarboxylase complement(3124737..3126872) Escherichia coli 536 4191094 YP_670845.1 CDS ECP_2960 NC_008253.1 3127271 3127978 D membrane protein YqgA 3127271..3127978 Escherichia coli 536 4191095 YP_670846.1 CDS ECP_2962 NC_008253.1 3128357 3129622 D P4-type integrase 3128357..3129622 Escherichia coli 536 4191097 YP_670847.1 CDS ECP_2963 NC_008253.1 3129973 3130362 D hypothetical protein 3129973..3130362 Escherichia coli 536 4191098 YP_670848.1 CDS ECP_2964 NC_008253.1 3130778 3130969 D transposase-like protein 3130778..3130969 Escherichia coli 536 4191099 YP_670849.1 CDS ECP_2965 NC_008253.1 3131239 3132021 R hypothetical protein complement(3131239..3132021) Escherichia coli 536 4191100 YP_670850.1 CDS ECP_2966 NC_008253.1 3132074 3133066 R PixG protein complement(3132074..3133066) Escherichia coli 536 4191101 YP_670851.1 CDS ECP_2967 NC_008253.1 3133089 3133607 R PixF protein complement(3133089..3133607) Escherichia coli 536 4191102 YP_670852.1 CDS ECP_2968 NC_008253.1 3133691 3134254 R PixJ protein complement(3133691..3134254) Escherichia coli 536 4191103 YP_670853.1 CDS ECP_2969 NC_008253.1 3134291 3135163 R PixD protein complement(3134291..3135163) Escherichia coli 536 4191104 YP_670854.1 CDS ECP_2970 NC_008253.1 3135091 3137661 R fimbrial usher protein PixC complement(3135091..3137661) Escherichia coli 536 4191105 YP_670855.1 CDS ECP_2971 NC_008253.1 3137722 3138309 R PixH protein complement(3137722..3138309) Escherichia coli 536 4191106 YP_670856.1 CDS ECP_2972 NC_008253.1 3138395 3138928 R PixA protein complement(3138395..3138928) Escherichia coli 536 4191107 YP_670857.1 CDS ECP_2973 NC_008253.1 3139664 3139888 R hypothetical protein complement(3139664..3139888) Escherichia coli 536 4191108 YP_670858.1 CDS ECP_2974 NC_008253.1 3140041 3140535 R hypothetical protein complement(3140041..3140535) Escherichia coli 536 4191109 YP_670859.1 CDS ECP_2975 NC_008253.1 3140894 3142150 R transport activator complement(3140894..3142150) Escherichia coli 536 4191110 YP_670860.1 CDS ECP_2976 NC_008253.1 3142131 3144140 R regulatory protein complement(3142131..3144140) Escherichia coli 536 4191111 YP_670861.1 CDS ECP_2977 NC_008253.1 3144137 3145408 R regulatory protein complement(3144137..3145408) Escherichia coli 536 4188260 YP_670862.1 CDS ECP_2978 NC_008253.1 3145753 3147117 D transporter protein 3145753..3147117 Escherichia coli 536 4188261 YP_670863.1 CDS ECP_2979 NC_008253.1 3147160 3147525 D hypothetical protein 3147160..3147525 Escherichia coli 536 4188262 YP_670864.1 CDS ECP_2980 NC_008253.1 3147553 3147759 D hypothetical protein 3147553..3147759 Escherichia coli 536 4188263 YP_670865.1 CDS ECP_2981 NC_008253.1 3148065 3149078 R hypothetical protein complement(3148065..3149078) Escherichia coli 536 4188264 YP_670866.1 CDS ECP_2982 NC_008253.1 3149090 3150406 R L-fucose permease complement(3149090..3150406) Escherichia coli 536 4188265 YP_670867.1 CDS ECP_2983 NC_008253.1 3150434 3151354 R ribokinase sugar kinase complement(3150434..3151354) Escherichia coli 536 4188266 YP_670868.1 CDS ECP_2984 NC_008253.1 3151659 3152441 D DeoR family transcriptional regulator 3151659..3152441 Escherichia coli 536 4188267 YP_670869.1 CDS ECP_2985 NC_008253.1 3152542 3152658 R hypothetical protein complement(3152542..3152658) Escherichia coli 536 4188268 YP_670870.1 CDS ECP_2986 NC_008253.1 3152669 3152869 R hypothetical protein complement(3152669..3152869) Escherichia coli 536 4188269 YP_670871.1 CDS ECP_2987 NC_008253.1 3153510 3153731 R hypothetical protein complement(3153510..3153731) Escherichia coli 536 4188270 YP_670872.1 CDS ECP_2988 NC_008253.1 3153836 3154369 R hypothetical protein complement(3153836..3154369) Escherichia coli 536 4188271 YP_670873.1 CDS ECP_2989 NC_008253.1 3154363 3155202 R transposase (orfB) complement(3154363..3155202) Escherichia coli 536 4188272 YP_670874.1 CDS ECP_2990 NC_008253.1 3155229 3155531 R transposase complement(3155229..3155531) Escherichia coli 536 4188273 YP_670875.1 CDS ECP_2991 NC_008253.1 3155676 3155873 R hypothetical protein complement(3155676..3155873) Escherichia coli 536 4188274 YP_670876.1 CDS ECP_2992 NC_008253.1 3156120 3156545 R hypothetical protein complement(3156120..3156545) Escherichia coli 536 4188275 YP_670877.1 CDS ECP_2993 NC_008253.1 3156542 3156925 R hypothetical protein complement(3156542..3156925) Escherichia coli 536 4188276 YP_670878.1 CDS ECP_2994 NC_008253.1 3156995 3157216 D hypothetical protein 3156995..3157216 Escherichia coli 536 4188277 YP_670879.1 CDS ECP_2995 NC_008253.1 3157431 3158453 D transposase for insertion sequence IS100 3157431..3158453 Escherichia coli 536 4188278 YP_670880.1 CDS ECP_2996 NC_008253.1 3158453 3159232 D transposase/IS protein 3158453..3159232 Escherichia coli 536 4188296 YP_670881.1 CDS ECP_2997 NC_008253.1 3159276 3159854 R hypothetical protein complement(3159276..3159854) Escherichia coli 536 4188297 YP_670882.1 CDS ECP_2998 NC_008253.1 3160086 3160472 R hemolysin expression modulating protein complement(3160086..3160472) Escherichia coli 536 4188298 YP_670883.1 CDS ECP_2999 NC_008253.1 3161311 3162102 D hypothetical protein 3161311..3162102 Escherichia coli 536 4188299 YP_670884.1 CDS ECP_3000 NC_008253.1 3162486 3162692 D regulatory protein 3162486..3162692 Escherichia coli 536 4188300 YP_670885.1 CDS ECP_3001 NC_008253.1 3162786 3163388 D hypothetical protein 3162786..3163388 Escherichia coli 536 4188301 YP_670886.1 CDS ECP_3002 NC_008253.1 3163449 3163763 R hypothetical protein complement(3163449..3163763) Escherichia coli 536 4188302 YP_670887.1 CDS ECP_3003 NC_008253.1 3164148 3164360 D hypothetical protein 3164148..3164360 Escherichia coli 536 4188303 YP_670888.1 CDS ECP_3004 NC_008253.1 3164407 3164709 D hypothetical protein 3164407..3164709 Escherichia coli 536 4188304 YP_670889.1 CDS ECP_3005 NC_008253.1 3165098 3165310 D hypothetical protein 3165098..3165310 Escherichia coli 536 4188305 YP_670890.1 CDS ECP_3006 NC_008253.1 3165831 3166457 D hypothetical protein 3165831..3166457 Escherichia coli 536 4188306 YP_670891.1 CDS ECP_3007 NC_008253.1 3166597 3167271 R hypothetical protein complement(3166597..3167271) Escherichia coli 536 4188307 YP_670892.1 CDS ECP_3008 NC_008253.1 3167566 3168438 D hypothetical protein 3167566..3168438 Escherichia coli 536 4188308 YP_670893.1 CDS ECP_3009 NC_008253.1 3168808 3171654 D autotransporter 3168808..3171654 Escherichia coli 536 4188309 YP_670894.1 CDS ECP_3010 NC_008253.1 3171725 3171958 D hypothetical protein 3171725..3171958 Escherichia coli 536 4188310 YP_670895.1 CDS ECP_3011 NC_008253.1 3172049 3172867 D hypothetical protein 3172049..3172867 Escherichia coli 536 4188311 YP_670896.1 CDS ECP_3012 NC_008253.1 3172959 3173444 D hypothetical protein 3172959..3173444 Escherichia coli 536 4188312 YP_670897.1 CDS ECP_3013 NC_008253.1 3173460 3173936 D radC-like protein YeeS 3173460..3173936 Escherichia coli 536 4188313 YP_670898.1 CDS ECP_3014 NC_008253.1 3174005 3174226 D hypothetical protein 3174005..3174226 Escherichia coli 536 4188314 YP_670899.1 CDS ECP_3015 NC_008253.1 3174240 3174668 D hypothetical protein 3174240..3174668 Escherichia coli 536 4188315 YP_670900.1 CDS ECP_3016 NC_008253.1 3174758 3175135 D hypothetical protein 3174758..3175135 Escherichia coli 536 4189430 YP_670901.1 CDS ECP_3017 NC_008253.1 3175132 3175620 D hypothetical protein 3175132..3175620 Escherichia coli 536 4189431 YP_670902.1 CDS ECP_3018 NC_008253.1 3175587 3175829 D hypothetical protein 3175587..3175829 Escherichia coli 536 4189432 YP_670903.1 CDS ECP_3019 NC_008253.1 3175914 3176756 D hypothetical protein 3175914..3176756 Escherichia coli 536 4189433 YP_670904.1 CDS ECP_3020 NC_008253.1 3178080 3179063 D polysialic acid capsule expression protein KpsF 3178080..3179063 Escherichia coli 536 4189434 YP_670905.1 CDS ECP_3021 NC_008253.1 3179135 3180283 D capsule polysaccharide export inner-membrane protein KpsE 3179135..3180283 Escherichia coli 536 4189435 YP_670906.1 CDS ECP_3022 NC_008253.1 3180307 3181983 D polysialic acid transport protein KpsD precursor 3180307..3181983 Escherichia coli 536 4189436 YP_670907.1 CDS ECP_3023 NC_008253.1 3181993 3182733 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3181993..3182733 Escherichia coli 536 4189437 YP_670908.1 CDS ECP_3024 NC_008253.1 3182730 3184178 D capsule polysaccharide export protein KpsC 3182730..3184178 Escherichia coli 536 4189438 YP_670909.1 CDS ECP_3025 NC_008253.1 3184216 3184593 D hypothetical protein 3184216..3184593 Escherichia coli 536 4189439 YP_670910.1 CDS ECP_3026 NC_008253.1 3184702 3185253 D hypothetical protein 3184702..3185253 Escherichia coli 536 4189440 YP_670911.1 CDS ECP_3027 NC_008253.1 3185408 3186658 R capsule polysaccharide export protein KpsS complement(3185408..3186658) Escherichia coli 536 4189441 YP_670912.1 CDS ECP_3028 NC_008253.1 3186695 3188824 R capsule export protein KpsC complement(3186695..3188824) Escherichia coli 536 4189442 YP_670913.1 CDS ECP_3029 NC_008253.1 3189178 3190116 R hypothetical protein complement(3189178..3190116) Escherichia coli 536 4189443 YP_670914.1 CDS ECP_3030 NC_008253.1 3190094 3190381 R hypothetical protein complement(3190094..3190381) Escherichia coli 536 4189444 YP_670915.1 CDS ECP_3031 NC_008253.1 3190414 3191052 R hypothetical protein complement(3190414..3191052) Escherichia coli 536 4189445 YP_670916.1 CDS ECP_3032 NC_008253.1 3191049 3192008 R hypothetical protein complement(3191049..3192008) Escherichia coli 536 4189446 YP_670917.1 CDS ECP_3033 NC_008253.1 3192005 3192994 R hypothetical protein complement(3192005..3192994) Escherichia coli 536 4189447 YP_670918.1 CDS ECP_3034 NC_008253.1 3192991 3193881 R glycosyltransferase complement(3192991..3193881) Escherichia coli 536 4189448 YP_670919.1 CDS ECP_3035 NC_008253.1 3194876 3195544 R polysialic acid transport ATP-binding protein KpsT complement(3194876..3195544) Escherichia coli 536 4188355 YP_670920.1 CDS ECP_3036 NC_008253.1 3195541 3196317 R polysialic acid transport protein KpsM complement(3195541..3196317) Escherichia coli 536 4188356 YP_670921.1 CDS ECP_3037 NC_008253.1 3197373 3197909 R general secretion pathway protein YghD complement(3197373..3197909) Escherichia coli 536 4188357 YP_670922.2 CDS ECP_3038 NC_008253.1 3197911 3198771 R similar to general secretory pathway protein L; GspL-like protein complement(3197911..3198771) Escherichia coli 536 4188358 YP_670923.1 CDS ECP_3039 NC_008253.1 3199086 3200063 R type II secretion protein GspK complement(3199086..3200063) Escherichia coli 536 4188359 YP_670924.1 CDS ECP_3040 NC_008253.1 3200060 3200665 R type II secretion protein GspJ complement(3200060..3200665) Escherichia coli 536 4188360 YP_670925.1 CDS ECP_3041 NC_008253.1 3200662 3201033 R type II secretion protein GspI complement(3200662..3201033) Escherichia coli 536 4188361 YP_670926.1 CDS ECP_3042 NC_008253.1 3201030 3201593 R type II secretion protein GspH complement(3201030..3201593) Escherichia coli 536 4188362 YP_670927.1 CDS ECP_3043 NC_008253.1 3201597 3202052 R type II secretion protein complement(3201597..3202052) Escherichia coli 536 4188363 YP_670928.1 CDS ECP_3044 NC_008253.1 3202069 3203292 R type II secretion protein GspF complement(3202069..3203292) Escherichia coli 536 4188364 YP_670929.1 CDS ECP_3045 NC_008253.1 3203292 3204785 R type II secretion protein GspE complement(3203292..3204785) Escherichia coli 536 4188365 YP_670930.1 CDS ECP_3046 NC_008253.1 3204785 3206845 R type II secretion protein GspD complement(3204785..3206845) Escherichia coli 536 4188366 YP_670931.1 CDS ECP_3047 NC_008253.1 3206875 3207834 R part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC complement(3206875..3207834) Escherichia coli 536 4188367 YP_670932.1 CDS ECP_3048 NC_008253.1 3207852 3208262 R lipoprotein complement(3207852..3208262) Escherichia coli 536 4188368 YP_670933.1 CDS ECP_3049 NC_008253.1 3208328 3209137 R prepilin peptidase complement(3208328..3209137) Escherichia coli 536 4188369 YP_670934.1 CDS ECP_3050 NC_008253.1 3209277 3213842 R lipoprotein AcfD complement(3209277..3213842) Escherichia coli 536 4188370 YP_670935.1 CDS ECP_3051 NC_008253.1 3213993 3214193 D hypothetical protein 3213993..3214193 Escherichia coli 536 4188371 YP_670936.1 CDS ECP_3052 NC_008253.1 3214327 3216009 R glycolate transporter complement(3214327..3216009) Escherichia coli 536 4188372 YP_670937.1 CDS ECP_3053 NC_008253.1 3216364 3218535 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3216364..3218535) Escherichia coli 536 4188373 YP_670938.1 CDS ECP_3054 NC_008253.1 3218557 3218961 R hypothetical protein complement(3218557..3218961) Escherichia coli 536 4188374 YP_670939.1 CDS glcF NC_008253.1 3218966 3220189 R glycolate oxidase iron-sulfur subunit complement(3218966..3220189) Escherichia coli 536 4189143 YP_670940.1 CDS glcE NC_008253.1 3220200 3221252 R glycolate oxidase FAD binding subunit complement(3220200..3221252) Escherichia coli 536 4189144 YP_670941.1 CDS ECP_3057 NC_008253.1 3221252 3222751 R glycolate oxidase subunit GlcD complement(3221252..3222751) Escherichia coli 536 4189145 YP_670942.1 CDS ECP_3058 NC_008253.1 3223002 3223766 D DNA-binding transcriptional regulator GlcC 3223002..3223766 Escherichia coli 536 4189146 YP_670943.1 CDS ECP_3059 NC_008253.1 3223773 3224915 R hypothetical protein complement(3223773..3224915) Escherichia coli 536 4189147 YP_670944.1 CDS ECP_3060 NC_008253.1 3225287 3227008 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3225287..3227008 Escherichia coli 536 4189148 YP_670945.1 CDS ECP_3061 NC_008253.1 3227005 3227919 D hypothetical protein 3227005..3227919 Escherichia coli 536 4189149 YP_670946.1 CDS ECP_3062 NC_008253.1 3227972 3228199 D acyl carrier protein 3227972..3228199 Escherichia coli 536 4189150 YP_670947.1 CDS ECP_3063 NC_008253.1 3228199 3229371 D aminotransferase 3228199..3229371 Escherichia coli 536 4189151 YP_670948.1 CDS ECP_3064 NC_008253.1 3229406 3230485 R permease complement(3229406..3230485) Escherichia coli 536 4189152 YP_670949.1 CDS ECP_3065 NC_008253.1 3230482 3231552 R permease complement(3230482..3231552) Escherichia coli 536 4189153 YP_670950.1 CDS ECP_3066 NC_008253.1 3231583 3232143 R hypothetical protein complement(3231583..3232143) Escherichia coli 536 4189154 YP_670951.1 CDS ECP_3067 NC_008253.1 3232155 3232979 R hypothetical protein complement(3232155..3232979) Escherichia coli 536 4189155 YP_670952.1 CDS ECP_3068 NC_008253.1 3232979 3234328 R hypothetical protein complement(3232979..3234328) Escherichia coli 536 4189156 YP_670953.1 CDS ECP_3069 NC_008253.1 3234374 3235132 R ATP-binding protein YghR complement(3234374..3235132) Escherichia coli 536 4189157 YP_670954.1 CDS ECP_3070 NC_008253.1 3235164 3235862 R ATP-binding protein YghS complement(3235164..3235862) Escherichia coli 536 4189158 YP_670955.1 CDS ECP_3071 NC_008253.1 3236051 3236743 D ATP-binding protein YghT 3236051..3236743 Escherichia coli 536 4189159 YP_670956.1 CDS ECP_3072 NC_008253.1 3236792 3238291 R inorganic phosphate transporter complement(3236792..3238291) Escherichia coli 536 4189160 YP_670957.1 CDS ECP_3073 NC_008253.1 3238583 3240442 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3238583..3240442) Escherichia coli 536 4189161 YP_670958.1 CDS ECP_3074 NC_008253.1 3240647 3240976 D hypothetical protein 3240647..3240976 Escherichia coli 536 4190498 YP_670959.1 CDS ECP_3075 NC_008253.1 3240930 3241514 D hypothetical protein 3240930..3241514 Escherichia coli 536 4190499 YP_670960.1 CDS ECP_3076 NC_008253.1 3241584 3241832 R hydrogenase 2 accessory protein HypG complement(3241584..3241832) Escherichia coli 536 4190500 YP_670961.1 CDS ECP_3077 NC_008253.1 3241845 3242186 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3241845..3242186) Escherichia coli 536 4190501 YP_670962.1 CDS ECP_3078 NC_008253.1 3242179 3242667 R hydrogenase 2-specific chaperone complement(3242179..3242667) Escherichia coli 536 4190502 YP_670963.1 CDS hybD NC_008253.1 3242660 3243154 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3242660..3243154) Escherichia coli 536 4190503 YP_670964.1 CDS ECP_3080 NC_008253.1 3243154 3244857 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3243154..3244857) Escherichia coli 536 4190504 YP_670965.1 CDS ECP_3081 NC_008253.1 3244854 3246032 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3244854..3246032) Escherichia coli 536 4190505 YP_670966.1 CDS ECP_3082 NC_008253.1 3246022 3247008 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3246022..3247008) Escherichia coli 536 4190506 YP_670967.1 CDS ECP_3083 NC_008253.1 3247011 3248129 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3247011..3248129) Escherichia coli 536 4190507 YP_670968.1 CDS ECP_3084 NC_008253.1 3248318 3248605 R hypothetical protein complement(3248318..3248605) Escherichia coli 536 4190508 YP_670969.1 CDS ECP_3085 NC_008253.1 3248724 3249614 R hydrolase complement(3248724..3249614) Escherichia coli 536 4190509 YP_670970.1 CDS ECP_3086 NC_008253.1 3249768 3250808 D aldo/keto reductase 3249768..3250808 Escherichia coli 536 4190510 YP_670971.1 CDS ECP_3087 NC_008253.1 3250848 3251342 R hypothetical protein complement(3250848..3251342) Escherichia coli 536 4190511 YP_670972.1 CDS ECP_3088 NC_008253.1 3251533 3252417 D oxidoreductase 3251533..3252417 Escherichia coli 536 4190512 YP_670973.1 CDS ECP_3089 NC_008253.1 3252456 3252881 R tonB-dependent uptake of B colicins; membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3252456..3252881) Escherichia coli 536 4190513 YP_670974.1 CDS ECP_3090 NC_008253.1 3252888 3253607 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3252888..3253607) Escherichia coli 536 4190514 YP_670975.1 CDS ECP_3091 NC_008253.1 3253874 3255061 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3253874..3255061 Escherichia coli 536 4190515 YP_670976.1 CDS ECP_3092 NC_008253.1 3255201 3255860 D hypothetical protein 3255201..3255860 Escherichia coli 536 4190516 YP_670977.1 CDS ECP_3093 NC_008253.1 3255900 3256967 R transcriptional regulator YqhC complement(3255900..3256967) Escherichia coli 536 4190517 YP_670978.1 CDS ECP_3094 NC_008253.1 3256993 3258156 D alcohol dehydrogenase 3256993..3258156 Escherichia coli 536 4190596 YP_670979.1 CDS dkgA NC_008253.1 3258261 3259088 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3258261..3259088 Escherichia coli 536 4190597 YP_670980.1 CDS ECP_3096 NC_008253.1 3259288 3260214 D hypothetical protein 3259288..3260214 Escherichia coli 536 4190598 YP_670981.1 CDS ECP_3097 NC_008253.1 3260265 3260522 D outer membrane lipoprotein 3260265..3260522 Escherichia coli 536 4190599 YP_670982.1 CDS ECP_3098 NC_008253.1 3260564 3262783 R hypothetical protein complement(3260564..3262783) Escherichia coli 536 4190600 YP_670983.1 CDS ECP_3099 NC_008253.1 3263035 3263784 D GntR family transcriptional regulator 3263035..3263784 Escherichia coli 536 4190601 YP_670984.1 CDS ECP_3100 NC_008253.1 3264107 3265579 D mannitol dehydrogenase 3264107..3265579 Escherichia coli 536 4190602 YP_670985.1 CDS ECP_3101 NC_008253.1 3265576 3266592 D zinc-binding dehydrogenase 3265576..3266592 Escherichia coli 536 4190603 YP_670986.1 CDS ECP_3102 NC_008253.1 3266603 3267613 D malate/L-lactate dehydrogenase 3266603..3267613 Escherichia coli 536 4190604 YP_670987.1 CDS ECP_3103 NC_008253.1 3267686 3268669 D C4-dicarboxylate transport system binding protein 3267686..3268669 Escherichia coli 536 4190605 YP_670988.1 CDS ECP_3104 NC_008253.1 3268711 3269193 D C4-dicarboxylate transport system 3268711..3269193 Escherichia coli 536 4190606 YP_670989.1 CDS ECP_3105 NC_008253.1 3269204 3270508 D C4-dicarboxylate transport system 3269204..3270508 Escherichia coli 536 4190607 YP_670990.1 CDS ECP_3106 NC_008253.1 3270579 3271991 R repressor protein for FtsI complement(3270579..3271991) Escherichia coli 536 4190608 YP_670991.1 CDS ECP_3107 NC_008253.1 3272066 3272803 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3272066..3272803) Escherichia coli 536 4190609 YP_670992.1 CDS ECP_3108 NC_008253.1 3273037 3275295 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3273037..3275295) Escherichia coli 536 4190610 YP_670993.1 CDS ECP_3109 NC_008253.1 3275433 3277040 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein complement(3275433..3277040) Escherichia coli 536 4190611 YP_670994.1 CDS ECP_3110 NC_008253.1 3277149 3277631 R AraC family transcriptional regulator complement(3277149..3277631) Escherichia coli 536 4190612 YP_670995.1 CDS ECP_3111 NC_008253.1 3277684 3278076 R protein YgiW complement(3277684..3278076) Escherichia coli 536 4190613 YP_670996.1 CDS ECP_3112 NC_008253.1 3278228 3278887 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3278228..3278887 Escherichia coli 536 4190614 YP_670997.1 CDS ECP_3113 NC_008253.1 3278884 3280233 D sensor protein QseC 3278884..3280233 Escherichia coli 536 4190673 YP_670998.1 CDS ECP_3114 NC_008253.1 3280343 3280924 D modulator of drug activity B 3280343..3280924 Escherichia coli 536 4190674 YP_670999.1 CDS ECP_3115 NC_008253.1 3280955 3281269 D hypothetical protein 3280955..3281269 Escherichia coli 536 4190675 YP_671000.1 CDS ECP_3116 NC_008253.1 3281314 3282201 R phosphosugar isomerase complement(3281314..3282201) Escherichia coli 536 4190676 YP_671001.1 CDS ECP_3117 NC_008253.1 3282198 3283145 R iron ABC transporter substrate-binding protein complement(3282198..3283145) Escherichia coli 536 4190677 YP_671002.1 CDS ECP_3118 NC_008253.1 3283156 3284205 R iron ABC transporter permease complement(3283156..3284205) Escherichia coli 536 4190678 YP_671003.1 CDS ECP_3119 NC_008253.1 3284202 3285185 R iron ABC transporter permease complement(3284202..3285185) Escherichia coli 536 4190679 YP_671004.1 CDS ECP_3120 NC_008253.1 3285182 3285991 R ferric enterobactin transport ATP-binding protein FepC complement(3285182..3285991) Escherichia coli 536 4190680 YP_671005.1 CDS ECP_3121 NC_008253.1 3286365 3288506 D iron compound receptor 3286365..3288506 Escherichia coli 536 4190681 YP_671006.1 CDS ECP_3122 NC_008253.1 3288570 3290462 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3288570..3290462) Escherichia coli 536 4190682 YP_671007.1 CDS ECP_3123 NC_008253.1 3290491 3291072 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(3290491..3291072) Escherichia coli 536 4190683 YP_671008.1 CDS ECP_3124 NC_008253.1 3291072 3291899 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3291072..3291899) Escherichia coli 536 4190684 YP_671009.1 CDS ECP_3125 NC_008253.1 3291924 3292346 R hypothetical protein complement(3291924..3292346) Escherichia coli 536 4190685 YP_671010.1 CDS nudF NC_008253.1 3292347 3292976 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase complement(3292347..3292976) Escherichia coli 536 4190686 YP_671011.1 CDS tolC NC_008253.1 3293181 3294662 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3293181..3294662 Escherichia coli 536 4190687 YP_671012.1 CDS ECP_3128 NC_008253.1 3294777 3295481 D hypothetical protein 3294777..3295481 Escherichia coli 536 4190688 YP_671013.1 CDS ECP_3129 NC_008253.1 3295487 3296647 D glutathionylspermidine synthase 3295487..3296647 Escherichia coli 536 4190689 YP_671014.1 CDS ECP_3130 NC_008253.1 3297132 3298928 D arylsulfate sulfotransferase 3297132..3298928 Escherichia coli 536 4190690 YP_671015.1 CDS ECP_3131 NC_008253.1 3298946 3299614 D thiol-disulfide isomerase and thioredoxin 3298946..3299614 Escherichia coli 536 4190691 YP_671016.1 CDS ECP_3132 NC_008253.1 3299644 3300300 D disulfide oxidoreductase 3299644..3300300 Escherichia coli 536 4190692 YP_671017.1 CDS ECP_3133 NC_008253.1 3300346 3301161 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3300346..3301161) Escherichia coli 536 4188550 YP_671018.1 CDS ECP_3134 NC_008253.1 3301277 3302050 D zinc transporter ZupT 3301277..3302050 Escherichia coli 536 4188551 YP_671019.1 CDS ECP_3135 NC_008253.1 3302108 3302278 R hypothetical protein complement(3302108..3302278) Escherichia coli 536 4188552 YP_671020.1 CDS ribB NC_008253.1 3302540 3303193 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3302540..3303193) Escherichia coli 536 4188553 YP_671021.1 CDS ECP_3137 NC_008253.1 3303568 3303867 D hypothetical protein 3303568..3303867 Escherichia coli 536 4188554 YP_671022.1 CDS ECP_3138 NC_008253.1 3303902 3304102 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3303902..3304102) Escherichia coli 536 4188555 YP_671023.1 CDS ECP_3139 NC_008253.1 3304371 3305000 D membrane protein YqiJ 3304371..3305000 Escherichia coli 536 4188556 YP_671024.1 CDS ECP_3140 NC_008253.1 3305027 3306688 D membrane protein YqiK 3305027..3306688 Escherichia coli 536 4188557 YP_671025.1 CDS ECP_3141 NC_008253.1 3307106 3308539 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3307106..3308539) Escherichia coli 536 4188558 YP_671026.1 CDS ECP_3142 NC_008253.1 3308587 3310758 R glutamate-ammonia-ligase adenylyltransferase complement(3308587..3310758) Escherichia coli 536 4188559 YP_671027.1 CDS ECP_3143 NC_008253.1 3310716 3311426 R glutamate-ammonia-ligase adenylyltransferase complement(3310716..3311426) Escherichia coli 536 4188560 YP_671028.1 CDS ECP_3144 NC_008253.1 3311449 3312750 R hypothetical protein complement(3311449..3312750) Escherichia coli 536 4188561 YP_671029.1 CDS ECP_3145 NC_008253.1 3312992 3313612 D signal transduction protein 3312992..3313612 Escherichia coli 536 4188562 YP_671030.1 CDS cca NC_008253.1 3313676 3314914 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3313676..3314914 Escherichia coli 536 4188563 YP_671031.1 CDS ECP_3147 NC_008253.1 3314995 3315816 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3314995..3315816) Escherichia coli 536 4188564 YP_671032.1 CDS folB NC_008253.1 3315907 3316275 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3315907..3316275) Escherichia coli 536 4188565 YP_671033.1 CDS ECP_3149 NC_008253.1 3316380 3316997 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3316380..3316997 Escherichia coli 536 4188566 YP_671034.1 CDS ECP_3150 NC_008253.1 3317010 3317942 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3317010..3317942) Escherichia coli 536 4188567 YP_671035.1 CDS ECP_3151 NC_008253.1 3318149 3319060 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3318149..3319060 Escherichia coli 536 4188568 YP_671036.1 CDS ECP_3152 NC_008253.1 3319057 3319662 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3319057..3319662 Escherichia coli 536 4188641 YP_671037.1 CDS ECP_3153 NC_008253.1 3319710 3321173 D tartrate carrier 3319710..3321173 Escherichia coli 536 4188642 YP_671038.1 CDS ECP_3154 NC_008253.1 3321216 3322229 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3321216..3322229) Escherichia coli 536 4188643 YP_671039.1 CDS rpsU NC_008253.1 3322467 3322682 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3322467..3322682 Escherichia coli 536 4188644 YP_671040.1 CDS dnaG NC_008253.1 3322793 3324538 D synthesizes RNA primers at the replication forks; DNA primase 3322793..3324538 Escherichia coli 536 4188645 YP_671041.1 CDS ECP_3157 NC_008253.1 3324733 3326574 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3324733..3326574 Escherichia coli 536 4188646 YP_671042.1 CDS ECP_3158 NC_008253.1 3326653 3327159 R G/U mismatch-specific DNA glycosylase complement(3326653..3327159) Escherichia coli 536 4188647 YP_671043.1 CDS ECP_3160 NC_008253.1 3327413 3328177 R hypothetical protein complement(3327413..3328177) Escherichia coli 536 4188649 YP_671044.1 CDS ECP_3161 NC_008253.1 3328465 3329088 D hypothetical protein 3328465..3329088 Escherichia coli 536 4188650 YP_671045.1 CDS ECP_3162 NC_008253.1 3329117 3330637 R aerotaxis receptor complement(3329117..3330637) Escherichia coli 536 4188651 YP_671046.1 CDS ECP_3163 NC_008253.1 3330944 3332434 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3330944..3332434 Escherichia coli 536 4188652 YP_671047.1 CDS ECP_3164 NC_008253.1 3332476 3332808 R hypothetical protein complement(3332476..3332808) Escherichia coli 536 4188653 YP_671048.1 CDS ECP_3165 NC_008253.1 3332915 3333097 D hypothetical protein 3332915..3333097 Escherichia coli 536 4188654 YP_671049.1 CDS ECP_3166 NC_008253.1 3333027 3334010 D DNA-binding transcriptional repressor EbgR 3333027..3334010 Escherichia coli 536 4188655 YP_671050.1 CDS ebgA NC_008253.1 3334194 3337286 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3334194..3337286 Escherichia coli 536 4188656 YP_671051.1 CDS ebgC NC_008253.1 3337283 3337732 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3337283..3337732 Escherichia coli 536 4188657 YP_671052.1 CDS ECP_3169 NC_008253.1 3337795 3339228 D transporter YgjI 3337795..3339228 Escherichia coli 536 4188658 YP_671053.1 CDS ECP_3170 NC_008253.1 3339362 3340432 D hypothetical protein 3339362..3340432 Escherichia coli 536 4188659 YP_671054.1 CDS ECP_3171 NC_008253.1 3340449 3342800 D glycosyl hydrolase 3340449..3342800 Escherichia coli 536 4188452 YP_671055.1 CDS ECP_3172 NC_008253.1 3342971 3344989 D 2,4-dienoyl-CoA reductase 3342971..3344989 Escherichia coli 536 4188453 YP_671056.1 CDS ECP_3173 NC_008253.1 3345082 3345498 R hypothetical protein complement(3345082..3345498) Escherichia coli 536 4188454 YP_671057.1 CDS ECP_3174 NC_008253.1 3345495 3345665 R hypothetical protein complement(3345495..3345665) Escherichia coli 536 4188455 YP_671058.1 CDS ECP_3175 NC_008253.1 3345769 3346905 R ribosomal RNA small subunit methyltransferase D complement(3345769..3346905) Escherichia coli 536 4188456 YP_671059.1 CDS ECP_3176 NC_008253.1 3346990 3347493 D hypothetical protein 3346990..3347493 Escherichia coli 536 4188457 YP_671060.1 CDS ECP_3177 NC_008253.1 3347570 3348253 D hypothetical protein 3347570..3348253 Escherichia coli 536 4188458 YP_671061.1 CDS ECP_3178 NC_008253.1 3348332 3349318 D oxidoreductase YgjR 3348332..3349318 Escherichia coli 536 4188459 YP_671062.1 CDS ECP_3179 NC_008253.1 3349601 3350566 D hypothetical protein 3349601..3350566 Escherichia coli 536 4188460 YP_671063.1 CDS ECP_3180 NC_008253.1 3350890 3352134 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3350890..3352134 Escherichia coli 536 4188461 YP_671064.1 CDS ECP_3181 NC_008253.1 3352138 3352689 R hypothetical protein complement(3352138..3352689) Escherichia coli 536 4188462 YP_671065.1 CDS ECP_3182 NC_008253.1 3352772 3354259 R altronate hydrolase complement(3352772..3354259) Escherichia coli 536 4188463 YP_671066.1 CDS ECP_3183 NC_008253.1 3354274 3355686 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3354274..3355686) Escherichia coli 536 4188464 YP_671067.1 CDS ECP_3184 NC_008253.1 3356169 3357467 D hexuronate transporter 3356169..3357467 Escherichia coli 536 4188465 YP_671068.1 CDS ECP_3185 NC_008253.1 3357543 3358625 R minor pilin protein complement(3357543..3358625) Escherichia coli 536 4188466 YP_671069.1 CDS ECP_3186 NC_008253.1 3358622 3361006 R usher protein complement(3358622..3361006) Escherichia coli 536 4188467 YP_671070.1 CDS ECP_3187 NC_008253.1 3360966 3361325 R hypothetical protein complement(3360966..3361325) Escherichia coli 536 4188468 YP_671071.1 CDS ECP_3188 NC_008253.1 3361398 3361898 R CS1 type fimbrial major subunit complement(3361398..3361898) Escherichia coli 536 4188469 YP_671072.1 CDS ECP_3189 NC_008253.1 3361928 3362644 R fimbrial protein complement(3361928..3362644) Escherichia coli 536 4188470 YP_671073.1 CDS ECP_3190 NC_008253.1 3362935 3363711 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3362935..3363711 Escherichia coli 536 4188491 YP_671074.1 CDS ECP_3191 NC_008253.1 3364056 3364718 D DedA family membrane protein 3364056..3364718 Escherichia coli 536 4188492 YP_671075.1 CDS ECP_3192 NC_008253.1 3364722 3365105 D hypothetical protein 3364722..3365105 Escherichia coli 536 4188493 YP_671076.2 CDS ECP_3193 NC_008253.1 3365252 3365620 D hypothetical protein 3365252..3365620 Escherichia coli 536 4188494 YP_671077.1 CDS ECP_3194 NC_008253.1 3365658 3365963 D hypothetical protein 3365658..3365963 Escherichia coli 536 4188495 YP_671078.1 CDS ECP_3195 NC_008253.1 3365966 3366370 D hypothetical protein 3365966..3366370 Escherichia coli 536 4188496 YP_671079.1 CDS ECP_3196 NC_008253.1 3366360 3366659 D hypothetical protein 3366360..3366659 Escherichia coli 536 4188497 YP_671080.1 CDS ECP_3197 NC_008253.1 3366846 3367238 D hypothetical protein 3366846..3367238 Escherichia coli 536 4188498 YP_671081.1 CDS ECP_3198 NC_008253.1 3367308 3368294 D glutathione S-transferase 3367308..3368294 Escherichia coli 536 4188499 YP_671082.1 CDS ECP_3199 NC_008253.1 3368577 3368945 D hypothetical protein 3368577..3368945 Escherichia coli 536 4188500 YP_671083.1 CDS ECP_3200 NC_008253.1 3368979 3369875 R LysR family transcriptional regulator complement(3368979..3369875) Escherichia coli 536 4188501 YP_671084.1 CDS ECP_3201 NC_008253.1 3369980 3370681 D hypothetical protein 3369980..3370681 Escherichia coli 536 4188502 YP_671085.1 CDS ECP_3202 NC_008253.1 3370704 3370868 D hypothetical protein 3370704..3370868 Escherichia coli 536 4188503 YP_671086.1 CDS ECP_3203 NC_008253.1 3370929 3372239 R hypothetical protein complement(3370929..3372239) Escherichia coli 536 4188504 YP_671087.1 CDS ECP_3204 NC_008253.1 3372267 3373598 R hypothetical protein complement(3372267..3373598) Escherichia coli 536 4188505 YP_671088.1 CDS ECP_3205 NC_008253.1 3373876 3375240 R L-serine dehydratase tdcG complement(3373876..3375240) Escherichia coli 536 4188506 YP_671089.1 CDS ECP_3206 NC_008253.1 3375312 3375701 R hypothetical protein complement(3375312..3375701) Escherichia coli 536 4188507 YP_671090.1 CDS ECP_3207 NC_008253.1 3375715 3378009 R keto-acid formate acetyltransferase complement(3375715..3378009) Escherichia coli 536 4188508 YP_671091.2 CDS ECP_3208 NC_008253.1 3378043 3379263 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3378043..3379263) Escherichia coli 536 4188509 YP_671092.1 CDS ECP_3209 NC_008253.1 3379277 3380608 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3379277..3380608) Escherichia coli 536 4188510 YP_671093.1 CDS ECP_3210 NC_008253.1 3380630 3381619 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3380630..3381619) Escherichia coli 536 4188531 YP_671094.1 CDS ECP_3211 NC_008253.1 3381718 3382656 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3381718..3382656) Escherichia coli 536 4188532 YP_671095.1 CDS ECP_3212 NC_008253.1 3382845 3383189 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3382845..3383189 Escherichia coli 536 4188533 YP_671096.1 CDS ECP_3213 NC_008253.1 3383778 3384227 D hypothetical protein 3383778..3384227 Escherichia coli 536 4188534 YP_671097.1 CDS ECP_3214 NC_008253.1 3384155 3385381 R glycerate kinase complement(3384155..3385381) Escherichia coli 536 4188535 YP_671098.1 CDS garR NC_008253.1 3385397 3386296 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3385397..3386296) Escherichia coli 536 4188536 YP_671099.1 CDS ECP_3216 NC_008253.1 3386317 3387087 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3386317..3387087) Escherichia coli 536 4188537 YP_671100.1 CDS ECP_3217 NC_008253.1 3387103 3388437 R galactarate transporter complement(3387103..3388437) Escherichia coli 536 4188538 YP_671101.1 CDS ECP_3218 NC_008253.1 3388812 3390383 D D-galactarate dehydratase 3388812..3390383 Escherichia coli 536 4188539 YP_671102.1 CDS ECP_3219 NC_008253.1 3390532 3390867 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 3390532..3390867 Escherichia coli 536 4188540 YP_671103.1 CDS ECP_3220 NC_008253.1 3390867 3391331 D hypothetical protein 3390867..3391331 Escherichia coli 536 4188541 YP_671104.1 CDS ECP_3221 NC_008253.1 3391386 3392195 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3391386..3392195) Escherichia coli 536 4188542 YP_671105.1 CDS ECP_3222 NC_008253.1 3392444 3393724 D tagatose 6-phosphate kinase agaZ 3392444..3393724 Escherichia coli 536 4188543 YP_671106.1 CDS ECP_3223 NC_008253.1 3393747 3394220 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IIB 3393747..3394220 Escherichia coli 536 4188544 YP_671107.1 CDS ECP_3224 NC_008253.1 3394231 3395010 D phosphotransferase system enzyme subunit (AgaW) 3394231..3395010 Escherichia coli 536 4188545 YP_671108.1 CDS ECP_3225 NC_008253.1 3395000 3395896 D PTS system N-acetylgalactosamine-specific transporter subunit IID 3395000..3395896 Escherichia coli 536 4188546 YP_671109.1 CDS ECP_3226 NC_008253.1 3395943 3396332 D phosphotransferase system enzyme subunit (AgaF) 3395943..3396332 Escherichia coli 536 4188547 YP_671110.1 CDS ECP_3227 NC_008253.1 3396329 3397462 D N-acetylgalctosamine-6-phosphate deacetylase 3396329..3397462 Escherichia coli 536 4188548 YP_671111.1 CDS ECP_3228 NC_008253.1 3397812 3398966 D tagatose-6-phosphate ketose/aldose isomerase 3397812..3398966 Escherichia coli 536 4188549 YP_671112.1 CDS kbaY NC_008253.1 3398979 3399839 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3398979..3399839 Escherichia coli 536 4188585 YP_671113.1 CDS ECP_3230 NC_008253.1 3400006 3400482 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IIB 3400006..3400482 Escherichia coli 536 4188586 YP_671114.1 CDS ECP_3231 NC_008253.1 3400521 3401324 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IIC 3400521..3401324 Escherichia coli 536 4188587 YP_671115.1 CDS ECP_3232 NC_008253.1 3401314 3402105 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IID 3401314..3402105 Escherichia coli 536 4188588 YP_671116.1 CDS ECP_3233 NC_008253.1 3402106 3402873 D galactosamine-6-phosphate isomerase 3402106..3402873 Escherichia coli 536 4188589 YP_671117.1 CDS ECP_3234 NC_008253.1 3402923 3403786 R tetrapyrrole methylase complement(3402923..3403786) Escherichia coli 536 4188590 YP_671118.1 CDS ECP_3235 NC_008253.1 3403851 3405887 D hypothetical protein 3403851..3405887 Escherichia coli 536 4188591 YP_671119.1 CDS ECP_3236 NC_008253.1 3405845 3406240 D hypothetical protein 3405845..3406240 Escherichia coli 536 4188592 YP_671120.1 CDS ECP_3237 NC_008253.1 3406260 3406850 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3406260..3406850 Escherichia coli 536 4188593 YP_671121.1 CDS ECP_3238 NC_008253.1 3406860 3407435 D hypothetical protein 3406860..3407435 Escherichia coli 536 4188594 YP_671122.1 CDS ECP_3239 NC_008253.1 3407548 3408588 R hypothetical protein complement(3407548..3408588) Escherichia coli 536 4188595 YP_671123.1 CDS ECP_3240 NC_008253.1 3408661 3409296 R hypothetical protein complement(3408661..3409296) Escherichia coli 536 4188596 YP_671124.1 CDS ECP_3241 NC_008253.1 3409424 3409942 D hypothetical protein 3409424..3409942 Escherichia coli 536 4188597 YP_671125.1 CDS ECP_3242 NC_008253.1 3409922 3410365 R hypothetical protein complement(3409922..3410365) Escherichia coli 536 4188598 YP_671126.1 CDS ECP_3243 NC_008253.1 3410416 3410718 D GIY-YIG nuclease superfamily protein 3410416..3410718 Escherichia coli 536 4188599 YP_671127.1 CDS ECP_3244 NC_008253.1 3410705 3411208 R acetyltransferase YhbS complement(3410705..3411208) Escherichia coli 536 4188600 YP_671128.1 CDS ECP_3245 NC_008253.1 3411202 3411750 R hypothetical protein complement(3411202..3411750) Escherichia coli 536 4188601 YP_671129.1 CDS ECP_3246 NC_008253.1 3411935 3412930 D protease YhbU 3411935..3412930 Escherichia coli 536 4188602 YP_671130.1 CDS ECP_3247 NC_008253.1 3412939 3413817 D peptidase YhbV 3412939..3413817 Escherichia coli 536 4188603 YP_671131.1 CDS ECP_3248 NC_008253.1 3413898 3414905 D hypothetical protein 3413898..3414905 Escherichia coli 536 4188604 YP_671132.1 CDS ECP_3249 NC_008253.1 3415023 3416267 R tryptophan transporter of high affinity; tryptophan permease complement(3415023..3416267) Escherichia coli 536 4188660 YP_671133.1 CDS ECP_3250 NC_008253.1 3416421 3418310 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3416421..3418310) Escherichia coli 536 4188661 YP_671134.1 CDS ECP_3251 NC_008253.1 3418490 3419374 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3418490..3419374) Escherichia coli 536 4188662 YP_671135.1 CDS ECP_3252 NC_008253.1 3419483 3421687 R polynucleotide phosphorylase complement(3419483..3421687) Escherichia coli 536 4188663 YP_671136.1 CDS rpsO NC_008253.1 3421865 3422134 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3421865..3422134) Escherichia coli 536 4188664 YP_671137.1 CDS truB NC_008253.1 3422283 3423227 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3422283..3423227) Escherichia coli 536 4188665 YP_671138.1 CDS rbfA NC_008253.1 3423227 3423628 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3423227..3423628) Escherichia coli 536 4188666 YP_671139.1 CDS infB NC_008253.1 3423792 3426464 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3423792..3426464) Escherichia coli 536 4188667 YP_671140.1 CDS nusA NC_008253.1 3426489 3427976 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3426489..3427976) Escherichia coli 536 4188668 YP_671141.1 CDS ECP_3258 NC_008253.1 3428004 3428456 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3428004..3428456) Escherichia coli 536 4188669 YP_671142.1 CDS ECP_3259 NC_008253.1 3429087 3430430 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3429087..3430430 Escherichia coli 536 4188670 YP_671143.1 CDS ECP_3260 NC_008253.1 3430438 3431169 R hypothetical protein complement(3430438..3431169) Escherichia coli 536 4188671 YP_671144.1 CDS ECP_3261 NC_008253.1 3431268 3431954 R hypothetical protein complement(3431268..3431954) Escherichia coli 536 4188672 YP_671145.1 CDS secG NC_008253.1 3432620 3432952 R preprotein translocase subunit SecG complement(3432620..3432952) Escherichia coli 536 4188673 YP_671146.1 CDS glmM NC_008253.1 3433180 3434517 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3433180..3434517) Escherichia coli 536 4188674 YP_671147.1 CDS folP NC_008253.1 3434510 3435358 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3434510..3435358) Escherichia coli 536 4188675 YP_671148.1 CDS hflB NC_008253.1 3435448 3437382 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3435448..3437382) Escherichia coli 536 4188676 YP_671149.1 CDS rrmJ NC_008253.1 3437482 3438111 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase complement(3437482..3438111) Escherichia coli 536 4188677 YP_671150.1 CDS ECP_3267 NC_008253.1 3438237 3438530 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3438237..3438530 Escherichia coli 536 4188678 YP_671151.1 CDS greA NC_008253.1 3438686 3439162 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3438686..3439162) Escherichia coli 536 4187661 YP_671152.1 CDS ECP_3269 NC_008253.1 3439410 3440843 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3439410..3440843 Escherichia coli 536 4187662 YP_671153.1 CDS obgE NC_008253.1 3440884 3442056 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3440884..3442056) Escherichia coli 536 4187663 YP_671154.1 CDS ECP_3271 NC_008253.1 3442072 3443037 R transporter complement(3442072..3443037) Escherichia coli 536 4187664 YP_671155.1 CDS rpmA NC_008253.1 3443165 3443422 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3443165..3443422) Escherichia coli 536 4187665 YP_671156.1 CDS rplU NC_008253.1 3443443 3443754 R 50S ribosomal protein L21 complement(3443443..3443754) Escherichia coli 536 4187666 YP_671157.1 CDS ECP_3274 NC_008253.1 3444013 3444984 D octaprenyl diphosphate synthase 3444013..3444984 Escherichia coli 536 4187667 YP_671158.1 CDS ECP_3275 NC_008253.1 3445217 3445495 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3445217..3445495 Escherichia coli 536 4187668 YP_671159.1 CDS ECP_3276 NC_008253.1 3445543 3446802 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3445543..3446802) Escherichia coli 536 4187669 YP_671160.1 CDS ECP_3277 NC_008253.1 3446857 3447126 R BolA family transcriptional regulator complement(3446857..3447126) Escherichia coli 536 4187670 YP_671161.1 CDS ECP_3278 NC_008253.1 3447271 3447564 R hypothetical protein complement(3447271..3447564) Escherichia coli 536 4187671 YP_671162.1 CDS ECP_3279 NC_008253.1 3447564 3448199 R hypothetical protein complement(3447564..3448199) Escherichia coli 536 4187672 YP_671163.1 CDS ECP_3280 NC_008253.1 3448218 3448769 R hypothetical protein complement(3448218..3448769) Escherichia coli 536 4187673 YP_671164.1 CDS ECP_3281 NC_008253.1 3448774 3449556 R hypothetical protein complement(3448774..3449556) Escherichia coli 536 4187674 YP_671165.1 CDS ECP_3282 NC_008253.1 3449564 3450373 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein complement(3449564..3450373) Escherichia coli 536 4187675 YP_671166.1 CDS ECP_3283 NC_008253.1 3450583 3451269 D sodium/calcium exchanger protein 3450583..3451269 Escherichia coli 536 4187676 YP_671167.1 CDS ECP_3284 NC_008253.1 3451344 3451559 D hypothetical protein 3451344..3451559 Escherichia coli 536 4187677 YP_671168.1 CDS ECP_3285 NC_008253.1 3451573 3452559 D D-arabinose 5-phosphate isomerase 3451573..3452559 Escherichia coli 536 4187678 YP_671169.1 CDS ECP_3286 NC_008253.1 3452580 3453146 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3452580..3453146 Escherichia coli 536 4187679 YP_671170.1 CDS ECP_3287 NC_008253.1 3453143 3453718 D hypothetical protein 3453143..3453718 Escherichia coli 536 4187680 YP_671171.1 CDS ECP_3288 NC_008253.1 3453687 3454244 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3453687..3454244 Escherichia coli 536 4189548 YP_671172.1 CDS ECP_3289 NC_008253.1 3454251 3454976 D ABC transporter ATP-binding protein 3454251..3454976 Escherichia coli 536 4189549 YP_671173.1 CDS ECP_3290 NC_008253.1 3455024 3456457 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3455024..3456457 Escherichia coli 536 4189550 YP_671174.1 CDS ECP_3291 NC_008253.1 3456480 3456767 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3456480..3456767 Escherichia coli 536 4189551 YP_671175.1 CDS ECP_3292 NC_008253.1 3456885 3457376 D PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 3456885..3457376 Escherichia coli 536 4189552 YP_671176.1 CDS ECP_3293 NC_008253.1 3457422 3458276 D hypothetical protein 3457422..3458276 Escherichia coli 536 4189553 YP_671177.1 CDS ECP_3294 NC_008253.1 3458273 3458545 D phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3458273..3458545 Escherichia coli 536 4189554 YP_671178.1 CDS ECP_3295 NC_008253.1 3458759 3459391 D hypothetical protein 3458759..3459391 Escherichia coli 536 4189555 YP_671179.1 CDS mtgA NC_008253.1 3459388 3460116 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3459388..3460116) Escherichia coli 536 4189556 YP_671180.1 CDS ECP_3297 NC_008253.1 3460113 3460766 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(3460113..3460766) Escherichia coli 536 4189557 YP_671181.1 CDS ECP_3298 NC_008253.1 3460996 3463332 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3460996..3463332) Escherichia coli 536 4189558 YP_671182.1 CDS ECP_3299 NC_008253.1 3463428 3464357 R hypothetical protein complement(3463428..3464357) Escherichia coli 536 4189559 YP_671183.1 CDS gltD NC_008253.1 3469506 3470924 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3469506..3470924 Escherichia coli 536 4189562 YP_671184.1 CDS ECP_3303 NC_008253.1 3471108 3472235 D hypothetical protein 3471108..3472235 Escherichia coli 536 4189563 YP_671185.1 CDS ECP_3304 NC_008253.1 3472295 3472759 R hypothetical protein complement(3472295..3472759) Escherichia coli 536 4189564 YP_671186.1 CDS ECP_3305 NC_008253.1 3472756 3473631 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3472756..3473631) Escherichia coli 536 4188825 YP_671187.1 CDS ECP_3306 NC_008253.1 3473628 3474317 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3473628..3474317) Escherichia coli 536 4188826 YP_671188.1 CDS ECP_3307 NC_008253.1 3474365 3475855 R sialic acid transporter complement(3474365..3475855) Escherichia coli 536 4188827 YP_671189.1 CDS ECP_3308 NC_008253.1 3475964 3476857 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3475964..3476857) Escherichia coli 536 4188828 YP_671190.1 CDS ECP_3309 NC_008253.1 3476979 3477770 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3476979..3477770) Escherichia coli 536 4188829 YP_671191.1 CDS ECP_3310 NC_008253.1 3477878 3478375 R ClpXP protease specificity-enhancing factor complement(3477878..3478375) Escherichia coli 536 4188830 YP_671192.1 CDS sspA NC_008253.1 3478381 3479019 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3478381..3479019) Escherichia coli 536 4188831 YP_671193.1 CDS ECP_3312 NC_008253.1 3478961 3479170 D hypothetical protein 3478961..3479170 Escherichia coli 536 4188832 YP_671194.1 CDS rpsI NC_008253.1 3479414 3479806 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3479414..3479806) Escherichia coli 536 4188833 YP_671195.1 CDS rplM NC_008253.1 3479822 3480250 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3479822..3480250) Escherichia coli 536 4188834 YP_671196.1 CDS ECP_3315 NC_008253.1 3480470 3481597 R ATPase complement(3480470..3481597) Escherichia coli 536 4188835 YP_671197.1 CDS ECP_3316 NC_008253.1 3481791 3482189 D cytochrome d ubiquinol oxidase subunit III 3481791..3482189 Escherichia coli 536 4188836 YP_671198.1 CDS ECP_3317 NC_008253.1 3482343 3483710 D serine endoprotease 3482343..3483710 Escherichia coli 536 4188837 YP_671199.1 CDS ECP_3318 NC_008253.1 3483800 3484867 D serine endoprotease 3483800..3484867 Escherichia coli 536 4188838 YP_671200.1 CDS ECP_3319 NC_008253.1 3484930 3485868 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3484930..3485868) Escherichia coli 536 4188839 YP_671201.1 CDS ECP_3320 NC_008253.1 3486146 3486319 D hypothetical protein 3486146..3486319 Escherichia coli 536 4188840 YP_671202.1 CDS ECP_3321 NC_008253.1 3486303 3486773 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3486303..3486773 Escherichia coli 536 4188841 YP_671203.1 CDS ECP_3322 NC_008253.1 3487137 3487400 D hypothetical protein 3487137..3487400 Escherichia coli 536 4188842 YP_671204.1 CDS ECP_3323 NC_008253.1 3487455 3487727 R hypothetical protein complement(3487455..3487727) Escherichia coli 536 4188843 YP_671205.1 CDS ECP_3324 NC_008253.1 3487819 3489786 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3487819..3489786) Escherichia coli 536 4190138 YP_671206.1 CDS ECP_3325 NC_008253.1 3489792 3490724 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3489792..3490724) Escherichia coli 536 4190139 YP_671207.1 CDS ECP_3326 NC_008253.1 3490732 3490935 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3490732..3490935) Escherichia coli 536 4190140 YP_671208.1 CDS ECP_3327 NC_008253.1 3491118 3492047 D DNA-binding transcriptional regulator 3491118..3492047 Escherichia coli 536 4190141 YP_671209.1 CDS tldD NC_008253.1 3492175 3493620 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3492175..3493620) Escherichia coli 536 4190142 YP_671210.1 CDS ECP_3329 NC_008253.1 3493776 3497576 R hypothetical protein complement(3493776..3497576) Escherichia coli 536 4190143 YP_671211.1 CDS ECP_3330 NC_008253.1 3497644 3499113 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3497644..3499113) Escherichia coli 536 4190144 YP_671212.1 CDS ECP_3331 NC_008253.1 3499103 3499696 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3499103..3499696) Escherichia coli 536 4190145 YP_671213.1 CDS ECP_3332 NC_008253.1 3499705 3500193 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3499705..3500193) Escherichia coli 536 4190146 YP_671214.1 CDS ECP_3333 NC_008253.1 3500193 3501296 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3500193..3501296) Escherichia coli 536 4190147 YP_671215.1 CDS ECP_3334 NC_008253.1 3501362 3502405 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3501362..3502405) Escherichia coli 536 4190148 YP_671216.1 CDS ECP_3335 NC_008253.1 3502513 3502701 D hypothetical protein 3502513..3502701 Escherichia coli 536 4190149 YP_671217.1 CDS ECP_3336 NC_008253.1 3502710 3504650 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3502710..3504650) Escherichia coli 536 4190150 YP_671218.1 CDS ECP_3337 NC_008253.1 3504802 3505776 D zinc-binding dehydrogenase 3504802..3505776 Escherichia coli 536 4190151 YP_671219.1 CDS ECP_3338 NC_008253.1 3505813 3505977 D hypothetical protein 3505813..3505977 Escherichia coli 536 4190152 YP_671220.1 CDS ECP_3339 NC_008253.1 3506185 3506349 D hypothetical protein 3506185..3506349 Escherichia coli 536 4190153 YP_671221.1 CDS ECP_3340 NC_008253.1 3506754 3507224 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3506754..3507224 Escherichia coli 536 4190154 YP_671222.1 CDS ECP_3341 NC_008253.1 3507235 3508584 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3507235..3508584 Escherichia coli 536 4190155 YP_671223.1 CDS ECP_3342 NC_008253.1 3508676 3509722 R hypothetical protein complement(3508676..3509722) Escherichia coli 536 4190156 YP_671224.1 CDS ECP_3343 NC_008253.1 3509719 3510681 R ribokinase sugar kinase complement(3509719..3510681) Escherichia coli 536 4190157 YP_671225.1 CDS ECP_3344 NC_008253.1 3510703 3511692 R sugar uptake ABC transporter permease complement(3510703..3511692) Escherichia coli 536 4188943 YP_671226.1 CDS ECP_3345 NC_008253.1 3511693 3513192 R sugar uptake ABC transporter ATP-binding protein complement(3511693..3513192) Escherichia coli 536 4188944 YP_671227.1 CDS ECP_3346 NC_008253.1 3513253 3514143 R sugar uptake ABC transporter periplasmic solute-binding protein complement(3513253..3514143) Escherichia coli 536 4188945 YP_671228.1 CDS gatY NC_008253.1 3514179 3515033 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(3514179..3515033) Escherichia coli 536 4188946 YP_671229.1 CDS ECP_3348 NC_008253.1 3515375 3516205 D DeoR family regulatory protein 3515375..3516205 Escherichia coli 536 4188947 YP_671230.1 CDS ECP_3349 NC_008253.1 3516216 3517172 D ribokinase sugar kinase 3516216..3517172 Escherichia coli 536 4188948 YP_671231.1 CDS ECP_3350 NC_008253.1 3517265 3517507 D hypothetical protein 3517265..3517507 Escherichia coli 536 4188949 YP_671232.1 CDS panF NC_008253.1 3517497 3518948 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3517497..3518948 Escherichia coli 536 4188950 YP_671233.1 CDS prmA NC_008253.1 3518960 3519841 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3518960..3519841 Escherichia coli 536 4188951 YP_671234.1 CDS ECP_3353 NC_008253.1 3520170 3521135 D tRNA-dihydrouridine synthase B 3520170..3521135 Escherichia coli 536 4188952 YP_671235.1 CDS fis NC_008253.1 3521161 3521457 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3521161..3521457 Escherichia coli 536 4188953 YP_671236.1 CDS ECP_3355 NC_008253.1 3521543 3522427 D methyltransferase 3521543..3522427 Escherichia coli 536 4188954 YP_671237.1 CDS ECP_3356 NC_008253.1 3522511 3522690 D hypothetical protein 3522511..3522690 Escherichia coli 536 4188955 YP_671238.1 CDS ECP_3357 NC_008253.1 3522693 3523355 R DNA-binding transcriptional regulator EnvR complement(3522693..3523355) Escherichia coli 536 4188956 YP_671239.1 CDS ECP_3358 NC_008253.1 3523556 3523765 R hypothetical protein complement(3523556..3523765) Escherichia coli 536 4188957 YP_671240.1 CDS ECP_3359 NC_008253.1 3523754 3524911 D acriflavine resistance protein E 3523754..3524911 Escherichia coli 536 4188958 YP_671241.1 CDS ECP_3360 NC_008253.1 3524923 3528027 D acriflavine resistance protein F 3524923..3528027 Escherichia coli 536 4188959 YP_671242.1 CDS ECP_3361 NC_008253.1 3528280 3528501 D hypothetical protein 3528280..3528501 Escherichia coli 536 4188960 YP_671243.1 CDS ECP_3362 NC_008253.1 3528727 3528903 D hypothetical protein 3528727..3528903 Escherichia coli 536 4188961 YP_671244.1 CDS ECP_3363 NC_008253.1 3528932 3529957 D amino-acid ABC transporter binding protein YhdW 3528932..3529957 Escherichia coli 536 4189258 YP_671245.1 CDS ECP_3364 NC_008253.1 3530025 3531206 D amino acid ABC transporter permease 3530025..3531206 Escherichia coli 536 4189259 YP_671246.1 CDS ECP_3365 NC_008253.1 3531216 3532319 D amino acid ABC transporter permease 3531216..3532319 Escherichia coli 536 4189260 YP_671247.1 CDS ECP_3366 NC_008253.1 3532327 3533085 D amino acid ABC transporter ATP-binding protein 3532327..3533085 Escherichia coli 536 4189261 YP_671248.1 CDS ECP_3367 NC_008253.1 3538877 3539431 D transferase 3538877..3539431 Escherichia coli 536 4189262 YP_671249.1 CDS ECP_3368 NC_008253.1 3539407 3539664 R hypothetical protein complement(3539407..3539664) Escherichia coli 536 4189263 YP_671250.1 CDS aroE NC_008253.1 3539661 3540479 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3539661..3540479) Escherichia coli 536 4189264 YP_671251.1 CDS ECP_3370 NC_008253.1 3540484 3541101 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3540484..3541101) Escherichia coli 536 4189265 YP_671252.1 CDS ECP_3371 NC_008253.1 3541061 3541603 R DNA topoisomerase complement(3541061..3541603) Escherichia coli 536 4189266 YP_671253.1 CDS ECP_3372 NC_008253.1 3541632 3542105 R hypothetical protein smg; hypothetical protein complement(3541632..3542105) Escherichia coli 536 4189267 YP_671254.1 CDS ECP_3373 NC_008253.1 3542077 3543201 R DNA protecting protein DprA complement(3542077..3543201) Escherichia coli 536 4189268 YP_671255.1 CDS def NC_008253.1 3543331 3543840 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3543331..3543840 Escherichia coli 536 4189269 YP_671256.1 CDS fmt NC_008253.1 3543855 3544802 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3543855..3544802 Escherichia coli 536 4189270 YP_671257.1 CDS ECP_3376 NC_008253.1 3544854 3546143 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3544854..3546143 Escherichia coli 536 4189271 YP_671258.1 CDS trkA NC_008253.1 3546165 3547541 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3546165..3547541 Escherichia coli 536 4189272 YP_671259.1 CDS mscL NC_008253.1 3547671 3548084 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3547671..3548084 Escherichia coli 536 4189273 YP_671260.1 CDS ECP_3379 NC_008253.1 3548081 3548299 R hypothetical protein complement(3548081..3548299) Escherichia coli 536 4189274 YP_671261.1 CDS zntR NC_008253.1 3548355 3548780 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3548355..3548780) Escherichia coli 536 4189275 YP_671262.1 CDS ECP_3381 NC_008253.1 3548791 3549159 R hypothetical protein complement(3548791..3549159) Escherichia coli 536 4189276 YP_671263.1 CDS rplQ NC_008253.1 3549266 3549649 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3549266..3549649) Escherichia coli 536 4189277 YP_671264.1 CDS ECP_3383 NC_008253.1 3549690 3550679 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3549690..3550679) Escherichia coli 536 4191209 YP_671265.1 CDS rpsD NC_008253.1 3550705 3551325 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3550705..3551325) Escherichia coli 536 4191210 YP_671266.1 CDS ECP_3385 NC_008253.1 3551359 3551748 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3551359..3551748) Escherichia coli 536 4191211 YP_671267.1 CDS rpsM NC_008253.1 3551765 3552121 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3551765..3552121) Escherichia coli 536 4191212 YP_671268.1 CDS rpmJ NC_008253.1 3552268 3552384 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3552268..3552384) Escherichia coli 536 4191213 YP_671269.1 CDS secY NC_008253.1 3552416 3553747 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3552416..3553747) Escherichia coli 536 4191214 YP_671270.1 CDS rplO NC_008253.1 3553755 3554189 R late assembly protein; 50S ribosomal protein L15 complement(3553755..3554189) Escherichia coli 536 4191215 YP_671271.1 CDS rpmD NC_008253.1 3554193 3554372 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3554193..3554372) Escherichia coli 536 4191216 YP_671272.1 CDS rpsE NC_008253.1 3554376 3554879 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3554376..3554879) Escherichia coli 536 4191217 YP_671273.1 CDS rplR NC_008253.1 3554894 3555247 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3554894..3555247) Escherichia coli 536 4191218 YP_671274.1 CDS rplF NC_008253.1 3555257 3555790 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3555257..3555790) Escherichia coli 536 4191219 YP_671275.1 CDS rpsH NC_008253.1 3555803 3556195 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3555803..3556195) Escherichia coli 536 4191220 YP_671276.1 CDS rpsN NC_008253.1 3556229 3556534 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3556229..3556534) Escherichia coli 536 4191221 YP_671277.1 CDS rplE NC_008253.1 3556549 3557088 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3556549..3557088) Escherichia coli 536 4191222 YP_671278.1 CDS rplX NC_008253.1 3557103 3557417 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3557103..3557417) Escherichia coli 536 4191223 YP_671279.1 CDS rplN NC_008253.1 3557428 3557799 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3557428..3557799) Escherichia coli 536 4191224 YP_671280.1 CDS rpsQ NC_008253.1 3557964 3558218 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3557964..3558218) Escherichia coli 536 4191225 YP_671281.1 CDS ECP_3400 NC_008253.1 3558218 3558409 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3558218..3558409) Escherichia coli 536 4191226 YP_671282.1 CDS rplP NC_008253.1 3558409 3558819 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3558409..3558819) Escherichia coli 536 4191227 YP_671283.1 CDS rpsC NC_008253.1 3558832 3559533 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3558832..3559533) Escherichia coli 536 4191480 YP_671284.1 CDS rplV NC_008253.1 3559551 3559883 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3559551..3559883) Escherichia coli 536 4191481 YP_671285.1 CDS rpsS NC_008253.1 3559898 3560176 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3559898..3560176) Escherichia coli 536 4191482 YP_671286.1 CDS rplB NC_008253.1 3560193 3561014 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3560193..3561014) Escherichia coli 536 4191483 YP_671287.1 CDS rplW NC_008253.1 3561032 3561334 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3561032..3561334) Escherichia coli 536 4191484 YP_671288.1 CDS rplD NC_008253.1 3561331 3561936 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3561331..3561936) Escherichia coli 536 4191485 YP_671289.1 CDS rplC NC_008253.1 3561947 3562576 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3561947..3562576) Escherichia coli 536 4191486 YP_671290.1 CDS rpsJ NC_008253.1 3562609 3562920 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3562609..3562920) Escherichia coli 536 4191487 YP_671291.1 CDS ECP_3410 NC_008253.1 3563158 3563577 R calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO complement(3563158..3563577) Escherichia coli 536 4191488 YP_671292.1 CDS ECP_3411 NC_008253.1 3563579 3565048 R general secretion pathway protein A complement(3563579..3565048) Escherichia coli 536 4191489 YP_671293.1 CDS ECP_3412 NC_008253.1 3565228 3566043 D general secretion pathway protein C 3565228..3566043 Escherichia coli 536 4191490 YP_671294.1 CDS ECP_3413 NC_008253.1 3566015 3567979 D general secretion pathway protein D 3566015..3567979 Escherichia coli 536 4191491 YP_671295.1 CDS ECP_3414 NC_008253.1 3567989 3569470 D general secretion pathway protein E 3567989..3569470 Escherichia coli 536 4191492 YP_671296.1 CDS ECP_3415 NC_008253.1 3569467 3570663 D general secretion pathway protein F 3569467..3570663 Escherichia coli 536 4191493 YP_671297.1 CDS ECP_3416 NC_008253.1 3570673 3571110 D general secretion pathway protein G 3570673..3571110 Escherichia coli 536 4191494 YP_671298.1 CDS ECP_3417 NC_008253.1 3571118 3571627 D general secretion pathway protein H 3571118..3571627 Escherichia coli 536 4191495 YP_671299.1 CDS ECP_3418 NC_008253.1 3571585 3572019 D general secretion pathway protein I 3571585..3572019 Escherichia coli 536 4191496 YP_671300.1 CDS ECP_3419 NC_008253.1 3572012 3572599 D general secretion pathway protein J 3572012..3572599 Escherichia coli 536 4191497 YP_671301.1 CDS ECP_3420 NC_008253.1 3572592 3573575 D general secretion pathway protein K 3572592..3573575 Escherichia coli 536 4191498 YP_671302.1 CDS ECP_3421 NC_008253.1 3573590 3574753 D general secretion pathway protein L 3573590..3574753 Escherichia coli 536 4191499 YP_671303.1 CDS ECP_3422 NC_008253.1 3574750 3575244 D general secretion pathway protein M 3574750..3575244 Escherichia coli 536 4190002 YP_671304.1 CDS ECP_3423 NC_008253.1 3575271 3576293 D transposase for insertion sequence IS100 3575271..3576293 Escherichia coli 536 4190003 YP_671305.1 CDS ECP_3424 NC_008253.1 3576293 3577072 D transposase/IS protein 3576293..3577072 Escherichia coli 536 4190004 YP_671306.1 CDS ECP_3425 NC_008253.1 3577170 3577847 D type 4 prepilin-like proteins leader peptide processing enzyme 3577170..3577847 Escherichia coli 536 4190005 YP_671307.1 CDS ECP_3426 NC_008253.1 3577876 3578352 R iron storage protein; bacterioferritin complement(3577876..3578352) Escherichia coli 536 4190006 YP_671308.1 CDS ECP_3427 NC_008253.1 3578424 3578618 R bacterioferritin-associated ferredoxin complement(3578424..3578618) Escherichia coli 536 4190007 YP_671309.1 CDS ECP_3428 NC_008253.1 3578787 3581489 R bifunctional chitinase/lysozyme complement(3578787..3581489) Escherichia coli 536 4190008 YP_671310.1 CDS ECP_3429 NC_008253.1 3581781 3582965 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3581781..3582965) Escherichia coli 536 4190009 YP_671311.1 CDS ECP_3430 NC_008253.1 3583036 3585150 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3583036..3585150) Escherichia coli 536 4190010 YP_671312.1 CDS ECP_3431 NC_008253.1 3585247 3585717 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3585247..3585717) Escherichia coli 536 4190011 YP_671313.1 CDS rpsL NC_008253.1 3585814 3586188 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3585814..3586188) Escherichia coli 536 4190012 YP_671314.1 CDS ECP_3433 NC_008253.1 3586314 3586601 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3586314..3586601) Escherichia coli 536 4190013 YP_671315.1 CDS ECP_3434 NC_008253.1 3586609 3586968 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3586609..3586968) Escherichia coli 536 4190014 YP_671316.1 CDS ECP_3435 NC_008253.1 3586968 3587354 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3586968..3587354) Escherichia coli 536 4190015 YP_671317.1 CDS ECP_3436 NC_008253.1 3587354 3588076 R hypothetical protein complement(3587354..3588076) Escherichia coli 536 4190016 YP_671318.1 CDS ECP_3437 NC_008253.1 3588243 3589055 R rotamase; FKBP-type peptidylprolyl isomerase complement(3588243..3589055) Escherichia coli 536 4190017 YP_671319.1 CDS ECP_3438 NC_008253.1 3589555 3590145 R rotamase; FKBP-type peptidylprolyl isomerase complement(3589555..3590145) Escherichia coli 536 4190018 YP_671320.1 CDS ECP_3439 NC_008253.1 3590240 3590440 R hypothetical protein complement(3590240..3590440) Escherichia coli 536 4190019 YP_671321.1 CDS ECP_3442 NC_008253.1 3592255 3592806 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3592255..3592806) Escherichia coli 536 4187871 YP_671322.1 CDS ECP_3443 NC_008253.1 3592937 3594850 D ABC transporter ATP-binding protein 3592937..3594850 Escherichia coli 536 4187872 YP_671323.1 CDS ECP_3444 NC_008253.1 3594850 3595872 D hydrolase 3594850..3595872 Escherichia coli 536 4187873 YP_671324.1 CDS ECP_3445 NC_008253.1 3595866 3596084 D hypothetical protein 3595866..3596084 Escherichia coli 536 4187874 YP_671325.1 CDS ECP_3446 NC_008253.1 3596138 3597007 D phosphoribulokinase 3596138..3597007 Escherichia coli 536 4187875 YP_671326.1 CDS ECP_3447 NC_008253.1 3597062 3597466 R hypothetical protein complement(3597062..3597466) Escherichia coli 536 4187876 YP_671327.1 CDS ECP_3448 NC_008253.1 3597768 3598400 D catabolite gene activator; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3597768..3598400 Escherichia coli 536 4187877 YP_671328.1 CDS ECP_3449 NC_008253.1 3598451 3600541 D hypothetical protein 3598451..3600541 Escherichia coli 536 4187878 YP_671329.1 CDS argD NC_008253.1 3600619 3601839 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase complement(3600619..3601839) Escherichia coli 536 4187879 YP_671330.1 CDS ECP_3451 NC_008253.1 3601925 3602488 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3601925..3602488) Escherichia coli 536 4187880 YP_671331.1 CDS ECP_3452 NC_008253.1 3602520 3603122 R cell filamentation protein Fic complement(3602520..3603122) Escherichia coli 536 4187881 YP_671332.1 CDS ECP_3453 NC_008253.1 3603112 3603279 R hypothetical protein complement(3603112..3603279) Escherichia coli 536 4187882 YP_671333.1 CDS ECP_3454 NC_008253.1 3603384 3603956 R peptidyl-prolyl cis-trans isomerase A complement(3603384..3603956) Escherichia coli 536 4187883 YP_671334.1 CDS ECP_3455 NC_008253.1 3604227 3605408 D hypothetical protein 3604227..3605408 Escherichia coli 536 4187884 YP_671335.1 CDS ECP_3456 NC_008253.1 3605670 3608213 D nitrite reductase [NAD(P)H] large subunit 3605670..3608213 Escherichia coli 536 4187885 YP_671336.1 CDS nirD NC_008253.1 3608210 3608536 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3608210..3608536 Escherichia coli 536 4187886 YP_671337.1 CDS ECP_3458 NC_008253.1 3608662 3609468 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3608662..3609468 Escherichia coli 536 4189031 YP_671338.1 CDS cysG NC_008253.1 3609487 3610860 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3609487..3610860 Escherichia coli 536 4189032 YP_671339.1 CDS ECP_3460 NC_008253.1 3611112 3611279 D hypothetical protein 3611112..3611279 Escherichia coli 536 4189033 YP_671340.1 CDS ECP_3461 NC_008253.1 3611386 3612471 R hypothetical protein complement(3611386..3612471) Escherichia coli 536 4189034 YP_671341.1 CDS ECP_3462 NC_008253.1 3612483 3613787 R hypothetical protein complement(3612483..3613787) Escherichia coli 536 4189035 YP_671342.1 CDS ECP_3463 NC_008253.1 3613799 3614152 R hypothetical protein complement(3613799..3614152) Escherichia coli 536 4189036 YP_671343.1 CDS ECP_3464 NC_008253.1 3614163 3615041 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3614163..3615041) Escherichia coli 536 4189037 YP_671344.1 CDS ECP_3465 NC_008253.1 3615038 3616264 R mutase complement(3615038..3616264) Escherichia coli 536 4189038 YP_671345.1 CDS ECP_3466 NC_008253.1 3616265 3617428 R hypothetical protein complement(3616265..3617428) Escherichia coli 536 4189039 YP_671346.1 CDS ECP_3467 NC_008253.1 3617512 3617874 R hypothetical protein complement(3617512..3617874) Escherichia coli 536 4189040 YP_671347.1 CDS ECP_3468 NC_008253.1 3617891 3618796 R hypothetical protein complement(3617891..3618796) Escherichia coli 536 4189041 YP_671348.1 CDS ECP_3469 NC_008253.1 3618956 3619960 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3618956..3619960) Escherichia coli 536 4189042 YP_671349.1 CDS ECP_3470 NC_008253.1 3619953 3620711 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3619953..3620711) Escherichia coli 536 4189043 YP_671350.1 CDS ECP_3471 NC_008253.1 3620704 3621381 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3620704..3621381) Escherichia coli 536 4189044 YP_671351.1 CDS ECP_3472 NC_008253.1 3621399 3622235 R DNA adenine methylase complement(3621399..3622235) Escherichia coli 536 4189045 YP_671352.1 CDS aroB NC_008253.1 3623722 3624810 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3623722..3624810) Escherichia coli 536 4191326 YP_671353.2 CDS aroK NC_008253.1 3624867 3625388 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3624867..3625388) Escherichia coli 536 4191327 YP_671354.1 CDS hofQ NC_008253.1 3625789 3627027 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3625789..3627027) Escherichia coli 536 4191328 YP_671355.1 CDS ECP_3478 NC_008253.1 3626939 3627343 R hypothetical protein complement(3626939..3627343) Escherichia coli 536 4191329 YP_671356.1 CDS ECP_3479 NC_008253.1 3627333 3627773 R hypothetical protein complement(3627333..3627773) Escherichia coli 536 4191330 YP_671357.1 CDS ECP_3480 NC_008253.1 3627757 3628296 R hypothetical protein complement(3627757..3628296) Escherichia coli 536 4191331 YP_671358.1 CDS ECP_3481 NC_008253.1 3628296 3629075 R hypothetical protein complement(3628296..3629075) Escherichia coli 536 4191332 YP_671359.1 CDS mrcA NC_008253.1 3629195 3631747 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3629195..3631747 Escherichia coli 536 4191333 YP_671360.1 CDS nudE NC_008253.1 3631914 3632474 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3631914..3632474) Escherichia coli 536 4191334 YP_671361.1 CDS ECP_3484 NC_008253.1 3632794 3634929 D membrane protein IgaA 3632794..3634929 Escherichia coli 536 4191335 YP_671362.1 CDS ECP_3485 NC_008253.1 3634994 3635662 D hydrolase 3634994..3635662 Escherichia coli 536 4191336 YP_671363.1 CDS ECP_3486 NC_008253.1 3635673 3636074 D ribosome-associated heat shock protein Hsp15 3635673..3636074 Escherichia coli 536 4191337 YP_671364.1 CDS hslO NC_008253.1 3636093 3636977 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3636093..3636977 Escherichia coli 536 4191338 YP_671365.1 CDS ECP_3488 NC_008253.1 3637040 3638764 R hypothetical protein complement(3637040..3638764) Escherichia coli 536 4191339 YP_671366.1 CDS ECP_3489 NC_008253.1 3639143 3640765 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3639143..3640765 Escherichia coli 536 4191340 YP_671367.1 CDS envZ NC_008253.1 3640842 3642194 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3640842..3642194) Escherichia coli 536 4191341 YP_671368.1 CDS ompR NC_008253.1 3642191 3642910 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3642191..3642910) Escherichia coli 536 4191342 YP_671369.1 CDS greB NC_008253.1 3643138 3643614 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3643138..3643614 Escherichia coli 536 4191343 YP_671370.1 CDS ECP_3493 NC_008253.1 3643711 3646032 D S1 RNA-binding domain-containing protein 3643711..3646032 Escherichia coli 536 4191344 YP_671371.1 CDS feoA NC_008253.1 3646470 3646697 D ferrous iron transport protein A 3646470..3646697 Escherichia coli 536 4191345 YP_671372.1 CDS feoB NC_008253.1 3646714 3649035 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3646714..3649035 Escherichia coli 536 4191346 YP_671373.1 CDS ECP_3496 NC_008253.1 3649046 3649282 D hypothetical protein 3649046..3649282 Escherichia coli 536 4191347 YP_671374.1 CDS ECP_3497 NC_008253.1 3649485 3650378 D hypothetical protein 3649485..3650378 Escherichia coli 536 4191348 YP_671375.1 CDS ECP_3498 NC_008253.1 3650598 3651368 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3650598..3651368) Escherichia coli 536 4191349 YP_671376.1 CDS ECP_3499 NC_008253.1 3651406 3652089 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3651406..3652089 Escherichia coli 536 4191350 YP_671377.1 CDS ECP_3500 NC_008253.1 3652148 3652723 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3652148..3652723 Escherichia coli 536 4191351 YP_671378.1 CDS ECP_3501 NC_008253.1 3653087 3654403 D high-affinity gluconate transporter 3653087..3654403 Escherichia coli 536 4191352 YP_671379.1 CDS malQ NC_008253.1 3654514 3656598 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3654514..3656598) Escherichia coli 536 4191353 YP_671380.1 CDS ECP_3503 NC_008253.1 3656608 3659001 R maltodextrin phosphorylase complement(3656608..3659001) Escherichia coli 536 4191354 YP_671381.1 CDS ECP_3504 NC_008253.1 3659624 3662329 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3659624..3662329 Escherichia coli 536 4191355 YP_671382.1 CDS ECP_3505 NC_008253.1 3662372 3663388 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3662372..3663388) Escherichia coli 536 4191356 YP_671383.1 CDS ECP_3506 NC_008253.1 3663392 3664618 R protein RtcB complement(3663392..3664618) Escherichia coli 536 4191357 YP_671384.1 CDS ECP_3507 NC_008253.1 3664807 3666405 D transcriptional regulatory protein RtcR 3664807..3666405 Escherichia coli 536 4191358 YP_671385.1 CDS ECP_3508 NC_008253.1 3666387 3667145 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3666387..3667145) Escherichia coli 536 4191359 YP_671386.1 CDS ECP_3509 NC_008253.1 3667162 3667992 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3667162..3667992) Escherichia coli 536 4191360 YP_671387.1 CDS glpE NC_008253.1 3668037 3668363 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3668037..3668363) Escherichia coli 536 4191361 YP_671388.1 CDS glpD NC_008253.1 3668553 3670058 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3668553..3670058 Escherichia coli 536 4191362 YP_671389.1 CDS ECP_3512 NC_008253.1 3670112 3670717 R hypothetical protein complement(3670112..3670717) Escherichia coli 536 4191363 YP_671390.1 CDS ECP_3513 NC_008253.1 3670720 3671496 R hypothetical protein complement(3670720..3671496) Escherichia coli 536 4191364 YP_671391.1 CDS ECP_3514 NC_008253.1 3671499 3672209 R hypothetical protein complement(3671499..3672209) Escherichia coli 536 4191385 YP_671392.1 CDS ECP_3515 NC_008253.1 3672383 3673504 R fimbrial adhesin complement(3672383..3673504) Escherichia coli 536 4191386 YP_671393.1 CDS ECP_3516 NC_008253.1 3673519 3674298 R fimbrial chaperone complement(3673519..3674298) Escherichia coli 536 4191387 YP_671394.1 CDS ECP_3517 NC_008253.1 3674264 3674836 R minor fimbrial subunit complement(3674264..3674836) Escherichia coli 536 4191388 YP_671395.1 CDS ECP_3518 NC_008253.1 3674787 3675350 R minor fimbrial subunit complement(3674787..3675350) Escherichia coli 536 4191389 YP_671396.1 CDS ECP_3519 NC_008253.1 3675350 3677944 R outer membrane usher protein complement(3675350..3677944) Escherichia coli 536 4191390 YP_671397.1 CDS ECP_3520 NC_008253.1 3677981 3678733 R fimbrial chaperone protein complement(3677981..3678733) Escherichia coli 536 4191391 YP_671398.1 CDS ECP_3521 NC_008253.1 3678834 3679538 R major fimbrial subunit complement(3678834..3679538) Escherichia coli 536 4191392 YP_671399.1 CDS ECP_3522 NC_008253.1 3680033 3682480 R glycogen phosphorylase complement(3680033..3682480) Escherichia coli 536 4191393 YP_671400.1 CDS glgA NC_008253.1 3682499 3683932 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3682499..3683932) Escherichia coli 536 4191394 YP_671401.1 CDS glgC NC_008253.1 3683932 3685227 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3683932..3685227) Escherichia coli 536 4191395 YP_671402.1 CDS ECP_3525 NC_008253.1 3685245 3687218 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3685245..3687218) Escherichia coli 536 4191396 YP_671403.1 CDS ECP_3526 NC_008253.1 3687215 3689401 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3687215..3689401) Escherichia coli 536 4191397 YP_671404.1 CDS ECP_3527 NC_008253.1 3689674 3690777 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3689674..3690777) Escherichia coli 536 4191398 YP_671405.1 CDS ECP_3528 NC_008253.1 3690969 3691562 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3690969..3691562 Escherichia coli 536 4191399 YP_671406.1 CDS ECP_3529 NC_008253.1 3691608 3692903 R DNA processing protein complement(3691608..3692903) Escherichia coli 536 4191400 YP_671407.1 CDS ECP_3530 NC_008253.1 3692810 3694906 R DNA helicase complement(3692810..3694906) Escherichia coli 536 4191401 YP_671408.1 CDS ECP_3531 NC_008253.1 3695047 3696387 R low affinity gluconate transporter complement(3695047..3696387) Escherichia coli 536 4191402 YP_671409.1 CDS gntK NC_008253.1 3696391 3696879 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3696391..3696879) Escherichia coli 536 4191403 YP_671410.1 CDS ECP_3533 NC_008253.1 3697057 3698052 R GalR/LacI family gluconate utilization operon gntUKR repressor complement(3697057..3698052) Escherichia coli 536 4191404 YP_671411.1 CDS ECP_3534 NC_008253.1 3698145 3698840 R pirin-related protein complement(3698145..3698840) Escherichia coli 536 4189489 YP_671412.1 CDS ECP_3535 NC_008253.1 3698963 3700000 R dehydrogenase complement(3698963..3700000) Escherichia coli 536 4189490 YP_671413.1 CDS ECP_3536 NC_008253.1 3700334 3700822 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3700334..3700822 Escherichia coli 536 4189491 YP_671414.1 CDS ECP_3537 NC_008253.1 3701058 3702242 D hypothetical protein 3701058..3702242 Escherichia coli 536 4189492 YP_671415.1 CDS ECP_3538 NC_008253.1 3702271 3702726 D hypothetical protein 3702271..3702726 Escherichia coli 536 4189493 YP_671416.1 CDS ECP_3539 NC_008253.1 3703176 3703460 D hypothetical protein 3703176..3703460 Escherichia coli 536 4189494 YP_671417.1 CDS ggt NC_008253.1 3703498 3705231 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3703498..3705231) Escherichia coli 536 4189495 YP_671418.1 CDS ECP_3541 NC_008253.1 3705351 3705791 D hypothetical protein 3705351..3705791 Escherichia coli 536 4189496 YP_671419.1 CDS ugpQ NC_008253.1 3705778 3706521 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3705778..3706521) Escherichia coli 536 4189497 YP_671420.1 CDS ugpC NC_008253.1 3706518 3707588 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3706518..3707588) Escherichia coli 536 4189498 YP_671421.1 CDS ECP_3544 NC_008253.1 3707590 3708435 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3707590..3708435) Escherichia coli 536 4189499 YP_671422.1 CDS ECP_3545 NC_008253.1 3708432 3709319 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3708432..3709319) Escherichia coli 536 4189500 YP_671423.1 CDS ECP_3546 NC_008253.1 3709417 3710733 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3709417..3710733) Escherichia coli 536 4189501 YP_671424.1 CDS livF NC_008253.1 3711130 3711843 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3711130..3711843) Escherichia coli 536 4189502 YP_671425.1 CDS livG NC_008253.1 3711845 3712612 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3711845..3712612) Escherichia coli 536 4189503 YP_671426.1 CDS livM NC_008253.1 3712609 3713886 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3712609..3713886) Escherichia coli 536 4189504 YP_671427.1 CDS ECP_3550 NC_008253.1 3713883 3714809 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3713883..3714809) Escherichia coli 536 4189505 YP_671428.1 CDS ECP_3551 NC_008253.1 3714857 3715966 R leucine-specific binding protein complement(3714857..3715966) Escherichia coli 536 4189506 YP_671429.1 CDS ECP_3552 NC_008253.1 3716390 3716773 D hypothetical protein 3716390..3716773 Escherichia coli 536 4189507 YP_671430.1 CDS ECP_3553 NC_008253.1 3716961 3718064 R Leu/Ile/Val-binding protein precursor complement(3716961..3718064) Escherichia coli 536 4189162 YP_671431.1 CDS ECP_3554 NC_008253.1 3718335 3719189 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3718335..3719189) Escherichia coli 536 4189163 YP_671432.1 CDS ftsX NC_008253.1 3719434 3720492 R ABC transporter membrane protein; cell division protein FtsX complement(3719434..3720492) Escherichia coli 536 4189164 YP_671433.1 CDS ECP_3556 NC_008253.1 3720485 3721153 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3720485..3721153) Escherichia coli 536 4189165 YP_671434.1 CDS ECP_3557 NC_008253.1 3721156 3722652 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3721156..3722652) Escherichia coli 536 4189166 YP_671435.1 CDS rsmD NC_008253.1 3722802 3723398 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3722802..3723398 Escherichia coli 536 4189167 YP_671436.1 CDS ECP_3559 NC_008253.1 3723388 3723657 D hypothetical protein 3723388..3723657 Escherichia coli 536 4189168 YP_671437.1 CDS ECP_3560 NC_008253.1 3723660 3724019 R hypothetical protein complement(3723660..3724019) Escherichia coli 536 4189169 YP_671438.1 CDS ECP_3561 NC_008253.1 3724160 3724786 D hypothetical protein 3724160..3724786 Escherichia coli 536 4189170 YP_671439.1 CDS zntA NC_008253.1 3724860 3727058 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3724860..3727058 Escherichia coli 536 4189171 YP_671440.1 CDS ECP_3563 NC_008253.1 3727236 3727958 R transposase complement(3727236..3727958) Escherichia coli 536 4189172 YP_671441.1 CDS ECP_3564 NC_008253.1 3728063 3728584 R IS transposase complement(3728063..3728584) Escherichia coli 536 4189173 YP_671442.1 CDS ECP_3565 NC_008253.1 3728763 3729008 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3728763..3729008) Escherichia coli 536 4189174 YP_671443.1 CDS ECP_3566 NC_008253.1 3729229 3729894 D hypothetical protein 3729229..3729894 Escherichia coli 536 4189175 YP_671444.1 CDS ECP_3567 NC_008253.1 3729967 3730524 D hypothetical protein 3729967..3730524 Escherichia coli 536 4189176 YP_671445.1 CDS ECP_3568 NC_008253.1 3730528 3731745 R major facilitator superfamily transporter complement(3730528..3731745) Escherichia coli 536 4189177 YP_671446.1 CDS ECP_3569 NC_008253.1 3731877 3732926 D hypothetical protein 3731877..3732926 Escherichia coli 536 4189178 YP_671447.1 CDS ECP_3570 NC_008253.1 3732981 3733568 D holo-(acyl carrier protein) synthase 2 3732981..3733568 Escherichia coli 536 4189179 YP_671448.1 CDS ECP_3571 NC_008253.1 3733679 3735253 D nickel-binding periplasmic protein 3733679..3735253 Escherichia coli 536 4189180 YP_671449.1 CDS ECP_3572 NC_008253.1 3735253 3736197 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3735253..3736197 Escherichia coli 536 4189181 YP_671450.1 CDS nikC NC_008253.1 3736194 3737027 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3736194..3737027 Escherichia coli 536 4187509 YP_671451.1 CDS nikD NC_008253.1 3737027 3737791 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3737027..3737791 Escherichia coli 536 4187510 YP_671452.1 CDS nikE NC_008253.1 3737788 3738594 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3737788..3738594 Escherichia coli 536 4187511 YP_671453.1 CDS ECP_3576 NC_008253.1 3738600 3739001 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3738600..3739001 Escherichia coli 536 4187512 YP_671454.1 CDS ECP_3577 NC_008253.1 3739010 3740134 R hypothetical protein complement(3739010..3740134) Escherichia coli 536 4187513 YP_671455.1 CDS ECP_3578 NC_008253.1 3740134 3742869 R ABC transporter ATP-binding protein complement(3740134..3742869) Escherichia coli 536 4187514 YP_671456.1 CDS ECP_3579 NC_008253.1 3742866 3743933 R hypothetical protein complement(3742866..3743933) Escherichia coli 536 4187515 YP_671457.1 CDS ECP_3580 NC_008253.1 3744209 3744415 D hypothetical protein 3744209..3744415 Escherichia coli 536 4187516 YP_671458.1 CDS ECP_3581 NC_008253.1 3744667 3745719 D hypothetical protein 3744667..3745719 Escherichia coli 536 4187517 YP_671459.1 CDS ECP_3582 NC_008253.1 3745806 3746999 R hypothetical protein complement(3745806..3746999) Escherichia coli 536 4187518 YP_671460.1 CDS ECP_3583 NC_008253.1 3747231 3748730 D low-affinity inorganic phosphate transporter 1 3747231..3748730 Escherichia coli 536 4187519 YP_671461.1 CDS ECP_3584 NC_008253.1 3748801 3749136 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3748801..3749136) Escherichia coli 536 4187520 YP_671462.1 CDS ECP_3585 NC_008253.1 3749527 3749961 D universal stress protein 3749527..3749961 Escherichia coli 536 4187521 YP_671463.1 CDS ECP_3586 NC_008253.1 3750278 3751747 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3750278..3751747 Escherichia coli 536 4187522 YP_671464.1 CDS ECP_3587 NC_008253.1 3751796 3752590 R predicted SAM-dependent methyltransferase; methyltransferase complement(3751796..3752590) Escherichia coli 536 4187523 YP_671465.1 CDS ECP_3588 NC_008253.1 3752556 3754598 R oligopeptidase A complement(3752556..3754598) Escherichia coli 536 4187524 YP_671466.1 CDS ECP_3589 NC_008253.1 3754801 3755643 D hypothetical protein 3754801..3755643 Escherichia coli 536 4187525 YP_671467.1 CDS ECP_3590 NC_008253.1 3755715 3757067 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3755715..3757067 Escherichia coli 536 4187526 YP_671468.1 CDS ECP_3591 NC_008253.1 3757232 3757405 D hypothetical protein 3757232..3757405 Escherichia coli 536 4187527 YP_671469.1 CDS ECP_3592 NC_008253.1 3757738 3758163 D arsenate reductase 3757738..3758163 Escherichia coli 536 4191150 YP_671470.1 CDS ECP_3593 NC_008253.1 3758780 3758953 D hypothetical protein 3758780..3758953 Escherichia coli 536 4191151 YP_671471.1 CDS ECP_3594 NC_008253.1 3759347 3759913 D outer membrane protein Slp 3759347..3759913 Escherichia coli 536 4191152 YP_671472.1 CDS ECP_3595 NC_008253.1 3760066 3760596 D transcriptional regulator YhiF 3760066..3760596 Escherichia coli 536 4191153 YP_671473.1 CDS ECP_3596 NC_008253.1 3760653 3761681 R heme/hemoglobin transport protein complement(3760653..3761681) Escherichia coli 536 4191154 YP_671474.1 CDS ECP_3597 NC_008253.1 3761730 3763712 R outer membrane hemin receptor complement(3761730..3763712) Escherichia coli 536 4191155 YP_671475.1 CDS ECP_3598 NC_008253.1 3763813 3763974 R hypothetical protein complement(3763813..3763974) Escherichia coli 536 4191156 YP_671476.1 CDS ECP_3599 NC_008253.1 3764124 3764288 R hypothetical protein complement(3764124..3764288) Escherichia coli 536 4191157 YP_671477.1 CDS ECP_3600 NC_008253.1 3764396 3765310 D hemin binding protein 3764396..3765310 Escherichia coli 536 4191158 YP_671478.1 CDS ECP_3601 NC_008253.1 3765330 3766667 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3765330..3766667 Escherichia coli 536 4191159 YP_671479.1 CDS ECP_3602 NC_008253.1 3766680 3767174 D hypothetical protein 3766680..3767174 Escherichia coli 536 4191160 YP_671480.1 CDS ECP_3603 NC_008253.1 3767174 3767797 D hypothetical protein 3767174..3767797 Escherichia coli 536 4191161 YP_671481.1 CDS ECP_3604 NC_008253.1 3767882 3768838 D permease of iron compound ABC transport system 3767882..3768838 Escherichia coli 536 4191162 YP_671482.1 CDS hmuV NC_008253.1 3768835 3769605 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3768835..3769605 Escherichia coli 536 4191163 YP_671483.1 CDS ECP_3606 NC_008253.1 3769657 3770304 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(3769657..3770304) Escherichia coli 536 4191164 YP_671484.1 CDS hdeB NC_008253.1 3770368 3770694 R acid-resistance protein complement(3770368..3770694) Escherichia coli 536 4191165 YP_671485.1 CDS ECP_3608 NC_008253.1 3770810 3771142 R inactive form; acid-resistance protein complement(3770810..3771142) Escherichia coli 536 4191166 YP_671486.1 CDS ECP_3609 NC_008253.1 3771397 3771969 D acid-resistance membrane protein 3771397..3771969 Escherichia coli 536 4191167 YP_671487.1 CDS ECP_3610 NC_008253.1 3772736 3773296 D hypothetical protein 3772736..3773296 Escherichia coli 536 4191168 YP_671488.1 CDS ECP_3611 NC_008253.1 3773346 3773633 D hypothetical protein 3773346..3773633 Escherichia coli 536 4191169 YP_671489.1 CDS ECP_3612 NC_008253.1 3773635 3774792 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3773635..3774792 Escherichia coli 536 4191248 YP_671490.1 CDS ECP_3613 NC_008253.1 3774817 3777930 D hypothetical protein 3774817..3777930 Escherichia coli 536 4191249 YP_671491.1 CDS ECP_3614 NC_008253.1 3778293 3779021 R transcriptional regulator YhiW complement(3778293..3779021) Escherichia coli 536 4191250 YP_671492.1 CDS ECP_3615 NC_008253.1 3779390 3780214 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3779390..3780214) Escherichia coli 536 4191251 YP_671493.1 CDS ECP_3616 NC_008253.1 3780582 3781982 R glutamate decarboxylase complement(3780582..3781982) Escherichia coli 536 4191252 YP_671494.1 CDS ECP_3617 NC_008253.1 3782193 3782489 R similar to the C-terminal part of the probable cytochrome C peroxidase YhjA; hypothetical protein complement(3782193..3782489) Escherichia coli 536 4191253 YP_671495.1 CDS ECP_3618 NC_008253.1 3782585 3783589 R similar to the N-terminal part of the probable cytochrome C peroxidase YhjA; hypothetical protein complement(3782585..3783589) Escherichia coli 536 4191254 YP_671496.1 CDS treF NC_008253.1 3783994 3785643 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3783994..3785643 Escherichia coli 536 4191255 YP_671497.1 CDS ECP_3620 NC_008253.1 3785694 3786296 R transcriptional regulator YhjB complement(3785694..3786296) Escherichia coli 536 4191256 YP_671498.1 CDS ECP_3621 NC_008253.1 3786744 3787664 D transcriptional regulator YhjC 3786744..3787664 Escherichia coli 536 4191257 YP_671499.1 CDS ECP_3622 NC_008253.1 3787763 3788776 D tRNA-processing ribonuclease 3787763..3788776 Escherichia coli 536 4191258 YP_671500.1 CDS ECP_3623 NC_008253.1 3789169 3790491 D metabolite transport protein YhjE 3789169..3790491 Escherichia coli 536 4191259 YP_671501.1 CDS ECP_3624 NC_008253.1 3790670 3792745 R AsmA family protein complement(3790670..3792745) Escherichia coli 536 4191260 YP_671502.1 CDS ECP_3625 NC_008253.1 3792800 3793567 R in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase complement(3792800..3793567) Escherichia coli 536 4191261 YP_671503.1 CDS ECP_3626 NC_008253.1 3793799 3794728 D 2-dehydro-3-deoxygluconokinase 3793799..3794728 Escherichia coli 536 4191262 YP_671504.1 CDS ECP_3627 NC_008253.1 3794824 3796320 R protein YhjJ complement(3794824..3796320) Escherichia coli 536 4191263 YP_671505.1 CDS ECP_3628 NC_008253.1 3796540 3797826 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3796540..3797826) Escherichia coli 536 4191264 YP_671506.2 CDS ECP_3629 NC_008253.1 3798009 3799964 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase complement(3798009..3799964) Escherichia coli 536 4191265 YP_671507.1 CDS ECP_3630 NC_008253.1 3800079 3803552 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3800079..3803552) Escherichia coli 536 4191266 YP_671508.1 CDS ECP_3631 NC_008253.1 3803534 3804640 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3803534..3804640) Escherichia coli 536 4191500 YP_671509.1 CDS ECP_3632 NC_008253.1 3804647 3806986 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3804647..3806986) Escherichia coli 536 4191501 YP_671510.1 CDS bcsA NC_008253.1 3806997 3809615 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3806997..3809615) Escherichia coli 536 4191502 YP_671511.1 CDS ECP_3634 NC_008253.1 3809612 3810364 R cell division protein complement(3809612..3810364) Escherichia coli 536 4191503 YP_671512.1 CDS ECP_3635 NC_008253.1 3810376 3810564 R hypothetical protein complement(3810376..3810564) Escherichia coli 536 4191504 YP_671513.1 CDS ECP_3636 NC_008253.1 3810849 3812408 D hypothetical protein 3810849..3812408 Escherichia coli 536 4191505 YP_671514.1 CDS ECP_3637 NC_008253.1 3812405 3812596 D hypothetical protein 3812405..3812596 Escherichia coli 536 4191506 YP_671515.1 CDS ECP_3638 NC_008253.1 3812593 3814272 D hypothetical protein 3812593..3814272 Escherichia coli 536 4191507 YP_671516.1 CDS ECP_3639 NC_008253.1 3814359 3814634 R hypothetical protein complement(3814359..3814634) Escherichia coli 536 4191508 YP_671517.1 CDS ECP_3640 NC_008253.1 3814942 3816213 D transporter 3814942..3816213 Escherichia coli 536 4191509 YP_671518.1 CDS dppF NC_008253.1 3816243 3817247 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(3816243..3817247) Escherichia coli 536 4191510 YP_671519.1 CDS dppD NC_008253.1 3817244 3818227 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(3817244..3818227) Escherichia coli 536 4191511 YP_671520.1 CDS ECP_3643 NC_008253.1 3818238 3819140 R dipeptide transporter complement(3818238..3819140) Escherichia coli 536 4191512 YP_671521.1 CDS ECP_3644 NC_008253.1 3819150 3820169 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(3819150..3820169) Escherichia coli 536 4191513 YP_671523.1 CDS ECP_3646 NC_008253.1 3820476 3822083 R periplasmic dipeptide transport protein complement(3820476..3822083) Escherichia coli 536 4191515 YP_671525.1 CDS ECP_3648 NC_008253.1 3823012 3824703 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(3823012..3824703) Escherichia coli 536 4191517 YP_671526.1 CDS ECP_3649 NC_008253.1 3825027 3826235 R hypothetical protein complement(3825027..3826235) Escherichia coli 536 4191518 YP_671527.1 CDS ECP_3650 NC_008253.1 3826464 3827162 R hypothetical protein complement(3826464..3827162) Escherichia coli 536 4191519 YP_671528.1 CDS ECP_3653 NC_008253.1 3827880 3828320 D hypothetical protein 3827880..3828320 Escherichia coli 536 4188718 YP_671529.1 CDS ECP_3654 NC_008253.1 3828289 3830622 R biotin sulfoxide reductase complement(3828289..3830622) Escherichia coli 536 4188719 YP_671530.1 CDS ECP_3655 NC_008253.1 3830775 3831434 D outer membrane lipoprotein 3830775..3831434 Escherichia coli 536 4188720 YP_671531.1 CDS ECP_3656 NC_008253.1 3831538 3832512 D 2-ketogluconate reductase 3831538..3832512 Escherichia coli 536 4188721 YP_671532.1 CDS ECP_3657 NC_008253.1 3832562 3833272 R hypothetical protein complement(3832562..3833272) Escherichia coli 536 4188722 YP_671533.1 CDS ECP_3658 NC_008253.1 3833706 3833996 D transcriptional regulator 3833706..3833996 Escherichia coli 536 4188723 YP_671534.1 CDS ECP_3659 NC_008253.1 3834277 3834489 D major cold shock protein 3834277..3834489 Escherichia coli 536 4188724 YP_671535.1 CDS ECP_3660 NC_008253.1 3834677 3834889 R small toxic polypeptide complement(3834677..3834889) Escherichia coli 536 4188725 YP_671536.1 CDS glyS NC_008253.1 3835152 3837221 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(3835152..3837221) Escherichia coli 536 4188726 YP_671537.1 CDS glyQ NC_008253.1 3837231 3838142 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(3837231..3838142) Escherichia coli 536 4188727 YP_671538.1 CDS ECP_3663 NC_008253.1 3838237 3838518 R hypothetical protein complement(3838237..3838518) Escherichia coli 536 4188728 YP_671539.1 CDS ECP_3664 NC_008253.1 3838771 3839715 D hypothetical protein 3838771..3839715 Escherichia coli 536 4188729 YP_671540.1 CDS ECP_3665 NC_008253.1 3839756 3840193 R hypothetical protein complement(3839756..3840193) Escherichia coli 536 4188730 YP_671541.1 CDS ECP_3666 NC_008253.1 3840239 3840580 R hypothetical protein complement(3840239..3840580) Escherichia coli 536 4188731 YP_671542.1 CDS ECP_3667 NC_008253.1 3840749 3842203 R xylulokinase complement(3840749..3842203) Escherichia coli 536 4188732 YP_671543.1 CDS ECP_3668 NC_008253.1 3842275 3843597 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(3842275..3843597) Escherichia coli 536 4188059 YP_671544.1 CDS xylF NC_008253.1 3843963 3844955 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3843963..3844955 Escherichia coli 536 4188060 YP_671545.2 CDS ECP_3670 NC_008253.1 3845033 3846574 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3845033..3846574 Escherichia coli 536 4188061 YP_671546.1 CDS ECP_3671 NC_008253.1 3846552 3847733 D xylose transport system permease XylH 3846552..3847733 Escherichia coli 536 4188062 YP_671547.1 CDS ECP_3672 NC_008253.1 3847811 3848989 D xylose operon regulatory protein 3847811..3848989 Escherichia coli 536 4188063 YP_671548.1 CDS ECP_3673 NC_008253.1 3849097 3849921 R hypothetical protein complement(3849097..3849921) Escherichia coli 536 4188064 YP_671549.1 CDS ECP_3674 NC_008253.1 3850071 3850244 D hypothetical protein 3850071..3850244 Escherichia coli 536 4188065 YP_671550.1 CDS malS NC_008253.1 3850241 3852271 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3850241..3852271 Escherichia coli 536 4188066 YP_671551.1 CDS avtA NC_008253.1 3852449 3853702 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3852449..3853702 Escherichia coli 536 4188067 YP_671552.1 CDS ECP_3677 NC_008253.1 3853854 3854327 R electron transport protein YsaA complement(3853854..3854327) Escherichia coli 536 4188068 YP_671553.1 CDS ECP_3678 NC_008253.1 3854429 3855277 R transcriptional regulator YiaJ complement(3854429..3855277) Escherichia coli 536 4188069 YP_671554.1 CDS ECP_3679 NC_008253.1 3855478 3856476 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3855478..3856476 Escherichia coli 536 4188070 YP_671555.1 CDS ECP_3680 NC_008253.1 3856488 3856952 D hypothetical protein 3856488..3856952 Escherichia coli 536 4188071 YP_671556.1 CDS ECP_3681 NC_008253.1 3856975 3857895 D hypothetical protein 3856975..3857895 Escherichia coli 536 4188072 YP_671557.1 CDS ECP_3682 NC_008253.1 3858009 3858476 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 3858009..3858476 Escherichia coli 536 4188073 YP_671558.1 CDS ECP_3683 NC_008253.1 3858479 3859756 D DedA family, membrane protein YiaN 3858479..3859756 Escherichia coli 536 4188074 YP_671559.1 CDS ECP_3684 NC_008253.1 3859769 3860755 D extracellular solute-binding protein YiaO 3859769..3860755 Escherichia coli 536 4188075 YP_671560.1 CDS ECP_3685 NC_008253.1 3860759 3862255 D cryptic L-xylulose kinase 3860759..3862255 Escherichia coli 536 4188076 YP_671561.1 CDS sgbH NC_008253.1 3862252 3862914 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3862252..3862914 Escherichia coli 536 4188077 YP_671562.1 CDS ECP_3687 NC_008253.1 3862907 3863767 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 3862907..3863767 Escherichia coli 536 4190857 YP_671563.1 CDS sgbE NC_008253.1 3863761 3864456 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3863761..3864456 Escherichia coli 536 4190858 YP_671564.1 CDS ECP_3691 NC_008253.1 3866208 3867359 R alcohol dehydrogenase complement(3866208..3867359) Escherichia coli 536 4190861 YP_671565.1 CDS ECP_3692 NC_008253.1 3867550 3869394 R selenocysteinyl-tRNA-specific translation factor complement(3867550..3869394) Escherichia coli 536 4190862 YP_671566.1 CDS ECP_3693 NC_008253.1 3869391 3870782 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(3869391..3870782) Escherichia coli 536 4190863 YP_671567.1 CDS ECP_3694 NC_008253.1 3870880 3871488 R glutathione S-transferase complement(3870880..3871488) Escherichia coli 536 4190864 YP_671568.1 CDS ECP_3695 NC_008253.1 3871559 3872695 R hypothetical protein complement(3871559..3872695) Escherichia coli 536 4190865 YP_671569.1 CDS ECP_3696 NC_008253.1 3872698 3873060 R hypothetical protein complement(3872698..3873060) Escherichia coli 536 4190866 YP_671570.1 CDS ECP_3697 NC_008253.1 3873597 3875510 D PTS system mannitol-specific transporter subunit IIABC 3873597..3875510 Escherichia coli 536 4190867 YP_671571.1 CDS ECP_3698 NC_008253.1 3876016 3877179 D mannitol-1-phosphate 5-dehydrogenase 3876016..3877179 Escherichia coli 536 4190868 YP_671572.1 CDS mtlR NC_008253.1 3877179 3877766 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 3877179..3877766 Escherichia coli 536 4190869 YP_671573.1 CDS ECP_3700 NC_008253.1 3877777 3877986 R hypothetical protein complement(3877777..3877986) Escherichia coli 536 4190870 YP_671574.1 CDS ECP_3701 NC_008253.1 3878270 3878632 D hypothetical protein 3878270..3878632 Escherichia coli 536 4190871 YP_671575.1 CDS ECP_3702 NC_008253.1 3879191 3879874 D hypothetical protein 3879191..3879874 Escherichia coli 536 4190872 YP_671576.1 CDS ECP_3703 NC_008253.1 3879918 3884792 D hemagglutinin/invasin 3879918..3884792 Escherichia coli 536 4190873 YP_671577.1 CDS ECP_3704 NC_008253.1 3885204 3886859 D L-lactate permease 3885204..3886859 Escherichia coli 536 4190274 YP_671578.1 CDS ECP_3705 NC_008253.1 3886859 3887635 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3886859..3887635 Escherichia coli 536 4190275 YP_671579.1 CDS lldD NC_008253.1 3887632 3888822 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3887632..3888822 Escherichia coli 536 4190276 YP_671580.1 CDS ECP_3707 NC_008253.1 3888870 3889343 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 3888870..3889343 Escherichia coli 536 4190277 YP_671581.1 CDS cysE NC_008253.1 3889398 3890219 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(3889398..3890219) Escherichia coli 536 4190278 YP_671582.1 CDS gpsA NC_008253.1 3890299 3891318 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(3890299..3891318) Escherichia coli 536 4190279 YP_671583.1 CDS ECP_3710 NC_008253.1 3891318 3891785 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(3891318..3891785) Escherichia coli 536 4190280 YP_671584.1 CDS ECP_3711 NC_008253.1 3891849 3892100 R glutaredoxin 3 complement(3891849..3892100) Escherichia coli 536 4190281 YP_671585.1 CDS ECP_3712 NC_008253.1 3892241 3892672 R hypothetical protein complement(3892241..3892672) Escherichia coli 536 4190282 YP_671586.1 CDS ECP_3713 NC_008253.1 3892917 3894461 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3892917..3894461 Escherichia coli 536 4190283 YP_671587.1 CDS ECP_3714 NC_008253.1 3894471 3895754 D hypothetical protein 3894471..3895754 Escherichia coli 536 4190284 YP_671588.1 CDS ECP_3715 NC_008253.1 3895758 3896717 D hypothetical protein 3895758..3896717 Escherichia coli 536 4190285 YP_671589.1 CDS ECP_3716 NC_008253.1 3896704 3897738 R glycosyl transferase family protein complement(3896704..3897738) Escherichia coli 536 4190286 YP_671590.1 CDS tdh NC_008253.1 3897977 3899002 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(3897977..3899002) Escherichia coli 536 4190287 YP_671591.1 CDS ECP_3718 NC_008253.1 3899012 3900208 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase complement(3899012..3900208) Escherichia coli 536 4190288 YP_671592.1 CDS rfaD NC_008253.1 3900422 3901354 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 3900422..3901354 Escherichia coli 536 4190289 YP_671593.1 CDS ECP_3720 NC_008253.1 3901364 3902410 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 3901364..3902410 Escherichia coli 536 4190290 YP_671594.1 CDS ECP_3721 NC_008253.1 3902414 3903394 D ADP-heptose--LPS heptosyltransferase 3902414..3903394 Escherichia coli 536 4190291 YP_671595.1 CDS ECP_3722 NC_008253.1 3903464 3904717 R lipid A-core:surface polymer ligase WaaL complement(3903464..3904717) Escherichia coli 536 4190292 YP_671596.1 CDS ECP_3723 NC_008253.1 3904763 3905746 R beta1,3-glucosyltransferase WaaV complement(3904763..3905746) Escherichia coli 536 4190293 YP_671597.1 CDS ECP_3724 NC_008253.1 3905828 3906856 R UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW complement(3905828..3906856) Escherichia coli 536 4189297 YP_671598.1 CDS ECP_3725 NC_008253.1 3906882 3907574 R lipopolysaccharide core biosynthesis protein complement(3906882..3907574) Escherichia coli 536 4189298 YP_671599.1 CDS ECP_3726 NC_008253.1 3907584 3908579 R UDP-galactose:(glucosyl) LPS alpha1,2-galactosyltransferase WaaT complement(3907584..3908579) Escherichia coli 536 4189299 YP_671600.1 CDS ECP_3727 NC_008253.1 3908596 3909612 R UDP-glucose:(glucosyl) LPS alpha1,3-glucosyltransferase WaaO complement(3908596..3909612) Escherichia coli 536 4189300 YP_671601.1 CDS ECP_3728 NC_008253.1 3909628 3910425 R lipopolysaccharide core biosynthesis protein WaaP complement(3909628..3910425) Escherichia coli 536 4189301 YP_671602.1 CDS ECP_3729 NC_008253.1 3910418 3911542 R UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG complement(3910418..3911542) Escherichia coli 536 4189302 YP_671603.1 CDS ECP_3730 NC_008253.1 3911539 3912561 R lipopolysaccharide core biosynthesis protein complement(3911539..3912561) Escherichia coli 536 4189303 YP_671604.1 CDS ECP_3731 NC_008253.1 3913010 3914287 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 3913010..3914287 Escherichia coli 536 4189304 YP_671605.1 CDS coaD NC_008253.1 3914295 3914774 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3914295..3914774 Escherichia coli 536 4189305 YP_671606.1 CDS ECP_3733 NC_008253.1 3914813 3915622 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(3914813..3915622) Escherichia coli 536 4189306 YP_671607.1 CDS rpmG NC_008253.1 3915720 3915887 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(3915720..3915887) Escherichia coli 536 4189307 YP_671608.1 CDS rpmB NC_008253.1 3915908 3916144 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(3915908..3916144) Escherichia coli 536 4189308 YP_671609.1 CDS radC NC_008253.1 3916361 3917005 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(3916361..3917005) Escherichia coli 536 4189309 YP_671610.1 CDS ECP_3737 NC_008253.1 3917201 3918421 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3917201..3918421 Escherichia coli 536 4189310 YP_671611.1 CDS dut NC_008253.1 3918399 3918857 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3918399..3918857 Escherichia coli 536 4189311 YP_671612.1 CDS slmA NC_008253.1 3918964 3919560 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 3918964..3919560 Escherichia coli 536 4189312 YP_671613.1 CDS pyrE NC_008253.1 3919597 3920238 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(3919597..3920238) Escherichia coli 536 4189313 YP_671614.1 CDS rph NC_008253.1 3920304 3921020 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(3920304..3921020) Escherichia coli 536 4189314 YP_671615.1 CDS ECP_3742 NC_008253.1 3921147 3922010 D hypothetical protein 3921147..3922010 Escherichia coli 536 4189315 YP_671616.1 CDS dinD NC_008253.1 3922231 3923055 D DNA-damage-inducible protein D 3922231..3923055 Escherichia coli 536 4191267 YP_671617.1 CDS ECP_3744 NC_008253.1 3923347 3923964 D hypothetical protein 3923347..3923964 Escherichia coli 536 4191268 YP_671618.1 CDS ligB NC_008253.1 3923961 3925646 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(3923961..3925646) Escherichia coli 536 4191269 YP_671619.1 CDS gmk NC_008253.1 3925901 3926524 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3925901..3926524 Escherichia coli 536 4191270 YP_671620.1 CDS rpoZ NC_008253.1 3926579 3926854 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3926579..3926854 Escherichia coli 536 4191271 YP_671621.1 CDS ECP_3748 NC_008253.1 3926873 3928981 D bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3926873..3928981 Escherichia coli 536 4191272 YP_671622.1 CDS ECP_3749 NC_008253.1 3928988 3929677 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 3928988..3929677 Escherichia coli 536 4191273 YP_671623.1 CDS ECP_3750 NC_008253.1 3929683 3931764 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3929683..3931764 Escherichia coli 536 4191274 YP_671624.1 CDS ECP_3751 NC_008253.1 3931798 3933003 R sodium/glutamate symport carrier protein complement(3931798..3933003) Escherichia coli 536 4191275 YP_671625.1 CDS ECP_3752 NC_008253.1 3933283 3934674 D purine permease YicE 3933283..3934674 Escherichia coli 536 4191276 YP_671626.1 CDS ECP_3753 NC_008253.1 3934771 3936504 D hypothetical protein 3934771..3936504 Escherichia coli 536 4191277 YP_671627.1 CDS ECP_3754 NC_008253.1 3936548 3937228 R hypothetical protein complement(3936548..3937228) Escherichia coli 536 4191278 YP_671628.1 CDS ECP_3755 NC_008253.1 3937209 3938141 R hypothetical protein complement(3937209..3938141) Escherichia coli 536 4191279 YP_671629.1 CDS ECP_3756 NC_008253.1 3938189 3939049 R hypothetical protein complement(3938189..3939049) Escherichia coli 536 4191280 YP_671630.1 CDS ECP_3757 NC_008253.1 3939130 3939981 R fructose-bisphosphate aldolase class-II complement(3939130..3939981) Escherichia coli 536 4191281 YP_671631.1 CDS ECP_3758 NC_008253.1 3939993 3941084 R PTS enzyme-II fructose complement(3939993..3941084) Escherichia coli 536 4191282 YP_671632.1 CDS ECP_3759 NC_008253.1 3941109 3941423 R PTS system, fructose-like-2 IIB component 1 complement(3941109..3941423) Escherichia coli 536 4191283 YP_671633.1 CDS ECP_3760 NC_008253.1 3941441 3941911 R phosphotransferase system (PTS), fructose-specific complement(3941441..3941911) Escherichia coli 536 4191284 YP_671634.1 CDS ECP_3761 NC_008253.1 3941938 3943491 R transcriptional antiterminator complement(3941938..3943491) Escherichia coli 536 4191285 YP_671635.1 CDS ECP_3762 NC_008253.1 3943786 3946104 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(3943786..3946104) Escherichia coli 536 4191286 YP_671636.1 CDS ECP_3763 NC_008253.1 3946114 3947541 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(3946114..3947541) Escherichia coli 536 4191462 YP_671637.1 CDS ECP_3765 NC_008253.1 3948173 3949354 D phage integrase 3948173..3949354 Escherichia coli 536 4191464 YP_671638.1 CDS ECP_3766 NC_008253.1 3949965 3950912 D type II 5-cytosoine methyltransferase 3949965..3950912 Escherichia coli 536 4191465 YP_671639.1 CDS ECP_3767 NC_008253.1 3950924 3951841 D type II 5-cytosoine methyltransferase 3950924..3951841 Escherichia coli 536 4191466 YP_671640.1 CDS ECP_3768 NC_008253.1 3951905 3953161 D hypothetical protein 3951905..3953161 Escherichia coli 536 4191467 YP_671641.1 CDS ECP_3769 NC_008253.1 3953679 3953927 D hypothetical protein 3953679..3953927 Escherichia coli 536 4191468 YP_671642.1 CDS ECP_3770 NC_008253.1 3954069 3954209 R hypothetical protein complement(3954069..3954209) Escherichia coli 536 4191469 YP_671643.1 CDS ECP_3771 NC_008253.1 3954835 3955068 D hypothetical protein 3954835..3955068 Escherichia coli 536 4191470 YP_671644.1 CDS ECP_3772 NC_008253.1 3955045 3955698 R transposase complement(3955045..3955698) Escherichia coli 536 4191471 YP_671645.1 CDS ECP_3773 NC_008253.1 3955801 3956583 R transposase/IS protein complement(3955801..3956583) Escherichia coli 536 4191472 YP_671646.1 CDS ECP_3774 NC_008253.1 3956580 3957602 R transposase complement(3956580..3957602) Escherichia coli 536 4191473 YP_671647.1 CDS ECP_3775 NC_008253.1 3957659 3958183 D hypothetical protein 3957659..3958183 Escherichia coli 536 4191474 YP_671648.1 CDS ECP_3776 NC_008253.1 3958381 3958932 R MarR family transcriptional regulator complement(3958381..3958932) Escherichia coli 536 4191475 YP_671649.1 CDS ECP_3777 NC_008253.1 3958961 3959170 R hypothetical protein complement(3958961..3959170) Escherichia coli 536 4191476 YP_671650.1 CDS ECP_3778 NC_008253.1 3959407 3959619 R hypothetical protein complement(3959407..3959619) Escherichia coli 536 4191477 YP_671651.1 CDS ECP_3779 NC_008253.1 3959662 3959808 D hypothetical protein 3959662..3959808 Escherichia coli 536 4191478 YP_671652.1 CDS ECP_3780 NC_008253.1 3960065 3960433 R hypothetical protein complement(3960065..3960433) Escherichia coli 536 4191479 YP_671653.1 CDS ECP_3781 NC_008253.1 3960415 3960690 D hypothetical protein 3960415..3960690 Escherichia coli 536 4191520 YP_671654.1 CDS ECP_3782 NC_008253.1 3960709 3961788 R F17-like fimbril adhesin subunit complement(3960709..3961788) Escherichia coli 536 4191521 YP_671655.1 CDS ECP_3783 NC_008253.1 3961785 3964319 R F17-like fimbrial usher complement(3961785..3964319) Escherichia coli 536 4191522 YP_671656.1 CDS ECP_3784 NC_008253.1 3964327 3965052 R F17-like fimbrial chaperone complement(3964327..3965052) Escherichia coli 536 4191523 YP_671657.1 CDS ECP_3785 NC_008253.1 3965110 3965661 R F17 fimbrial protein complement(3965110..3965661) Escherichia coli 536 4191524 YP_671658.1 CDS ECP_3786 NC_008253.1 3965689 3965955 D hypothetical protein 3965689..3965955 Escherichia coli 536 4191525 YP_671659.1 CDS ECP_3787 NC_008253.1 3966233 3966655 R hypothetical protein complement(3966233..3966655) Escherichia coli 536 4191526 YP_671660.1 CDS ECP_3788 NC_008253.1 3966658 3967887 R FMN-dependent dehydrogenase complement(3966658..3967887) Escherichia coli 536 4191527 YP_671661.1 CDS ECP_3789 NC_008253.1 3967926 3968474 R hypothetical protein complement(3967926..3968474) Escherichia coli 536 4191528 YP_671662.1 CDS ECP_3790 NC_008253.1 3968446 3969285 D transcription regulator protein 3968446..3969285 Escherichia coli 536 4191529 YP_671663.1 CDS ECP_3791 NC_008253.1 3969269 3969577 D hypothetical protein 3969269..3969577 Escherichia coli 536 4191530 YP_671664.1 CDS ECP_3792 NC_008253.1 3969628 3969846 R hypothetical protein complement(3969628..3969846) Escherichia coli 536 4191531 YP_671665.1 CDS ECP_3793 NC_008253.1 3970073 3970210 R hypothetical protein complement(3970073..3970210) Escherichia coli 536 4191532 YP_671666.1 CDS ECP_3794 NC_008253.1 3970254 3970457 D hypothetical protein 3970254..3970457 Escherichia coli 536 4191533 YP_671667.1 CDS ECP_3795 NC_008253.1 3970450 3970740 D transposase 3970450..3970740 Escherichia coli 536 4191534 YP_671668.1 CDS ECP_3796 NC_008253.1 3970733 3972415 D hypothetical protein 3970733..3972415 Escherichia coli 536 4191535 YP_671669.1 CDS ECP_3797 NC_008253.1 3972603 3972884 R hypothetical protein complement(3972603..3972884) Escherichia coli 536 4191536 YP_671670.1 CDS ECP_3798 NC_008253.1 3973972 3974538 D hypothetical protein 3973972..3974538 Escherichia coli 536 4191537 YP_671671.1 CDS ECP_3799 NC_008253.1 3974653 3975357 D hypothetical protein 3974653..3975357 Escherichia coli 536 4191538 YP_671672.1 CDS ECP_3800 NC_008253.1 3975426 3975659 D regulatory protein 3975426..3975659 Escherichia coli 536 4191539 YP_671673.1 CDS ECP_3801 NC_008253.1 3975656 3975814 D hypothetical protein 3975656..3975814 Escherichia coli 536 4191609 YP_671674.1 CDS ECP_3802 NC_008253.1 3975890 3976072 D hypothetical protein 3975890..3976072 Escherichia coli 536 4191610 YP_671675.1 CDS ECP_3803 NC_008253.1 3976106 3976387 D hypothetical protein 3976106..3976387 Escherichia coli 536 4191611 YP_671676.1 CDS ECP_3804 NC_008253.1 3976498 3976962 R transposase complement(3976498..3976962) Escherichia coli 536 4191612 YP_671677.1 CDS ECP_3805 NC_008253.1 3977161 3977388 R hypothetical protein complement(3977161..3977388) Escherichia coli 536 4191613 YP_671678.1 CDS ECP_3806 NC_008253.1 3977411 3978250 R transposase complement(3977411..3978250) Escherichia coli 536 4191614 YP_671679.1 CDS ECP_3807 NC_008253.1 3978277 3978579 R transposase complement(3978277..3978579) Escherichia coli 536 4191615 YP_671680.1 CDS ECP_3808 NC_008253.1 3978847 3979020 R hypothetical protein complement(3978847..3979020) Escherichia coli 536 4191616 YP_671681.1 CDS ECP_3809 NC_008253.1 3979072 3979209 D hypothetical protein 3979072..3979209 Escherichia coli 536 4191617 YP_671682.1 CDS ECP_3810 NC_008253.1 3979617 3980447 R CS12 fimbrial-like upstream regulatory protein complement(3979617..3980447) Escherichia coli 536 4191618 YP_671683.1 CDS ECP_3811 NC_008253.1 3980576 3981229 D hypothetical protein 3980576..3981229 Escherichia coli 536 4191619 YP_671684.1 CDS ECP_3812 NC_008253.1 3981285 3981986 D CS12 fimbria chaperone FasB-like protein 3981285..3981986 Escherichia coli 536 4191620 YP_671685.1 CDS ECP_3813 NC_008253.1 3981967 3982398 D CS12 fimbria chaperone protein 3981967..3982398 Escherichia coli 536 4191621 YP_671686.1 CDS ECP_3814 NC_008253.1 3982471 3984978 D CS12 fimbria outer membrane usher protein 3982471..3984978 Escherichia coli 536 4191622 YP_671687.1 CDS ECP_3815 NC_008253.1 3984966 3985418 D CS12 fimbria chaperone protein 3984966..3985418 Escherichia coli 536 4191623 YP_671688.1 CDS ECP_3816 NC_008253.1 3985408 3985956 D CS12 fimbria minor subunit protein 3985408..3985956 Escherichia coli 536 4191624 YP_671689.1 CDS ECP_3817 NC_008253.1 3985976 3987241 D FasG-like protein 3985976..3987241 Escherichia coli 536 4191625 YP_671690.1 CDS ECP_3818 NC_008253.1 3987475 3988671 R transposase complement(3987475..3988671) Escherichia coli 536 4191626 YP_671691.1 CDS ECP_3819 NC_008253.1 3988780 3988956 R hypothetical protein complement(3988780..3988956) Escherichia coli 536 4191627 YP_671692.1 CDS ECP_3820 NC_008253.1 3988997 3989359 R hypothetical protein complement(3988997..3989359) Escherichia coli 536 4191725 YP_671693.1 CDS ECP_3821 NC_008253.1 3989342 3989521 D hypothetical protein 3989342..3989521 Escherichia coli 536 4191726 YP_671694.1 CDS ECP_3822 NC_008253.1 3989622 3990458 D ABC transporter ATP-binding protein 3989622..3990458 Escherichia coli 536 4191727 YP_671695.1 CDS ECP_3823 NC_008253.1 3990383 3991309 D ABC-transporter membrane protein 3990383..3991309 Escherichia coli 536 4191728 YP_671696.1 CDS ECP_3824 NC_008253.1 3991353 3992231 D periplasmic binding protein 3991353..3992231 Escherichia coli 536 4191729 YP_671697.1 CDS ECP_3825 NC_008253.1 3992418 3992630 D hypothetical protein 3992418..3992630 Escherichia coli 536 4191730 YP_671698.1 CDS ECP_3826 NC_008253.1 3993046 3993558 D hemolysin-activating lysine-acyltransferase HlyC 3993046..3993558 Escherichia coli 536 4191731 YP_671699.1 CDS ECP_3827 NC_008253.1 3993570 3996644 D hemolysin A 3993570..3996644 Escherichia coli 536 4191732 YP_671700.1 CDS ECP_3828 NC_008253.1 3996715 3998838 D alpha-hemolysin translocation ATP-binding protein HlyB 3996715..3998838 Escherichia coli 536 4191733 YP_671701.1 CDS ECP_3829 NC_008253.1 3998857 4000293 D hemolysin D 3998857..4000293 Escherichia coli 536 4191734 YP_671702.1 CDS ECP_3830 NC_008253.1 4000591 4001511 D urea transporter 4000591..4001511 Escherichia coli 536 4191735 YP_671703.1 CDS ECP_3831 NC_008253.1 4001753 4002985 D phosphoadenosine phosphosulfate reductase 4001753..4002985 Escherichia coli 536 4191736 YP_671704.1 CDS ECP_3832 NC_008253.1 4002970 4003614 D ParB-like nuclease 4002970..4003614 Escherichia coli 536 4191737 YP_671705.1 CDS ECP_3833 NC_008253.1 4003655 4003861 R transposase complement(4003655..4003861) Escherichia coli 536 4191738 YP_671706.1 CDS ECP_3834 NC_008253.1 4003883 4004413 R transposase complement(4003883..4004413) Escherichia coli 536 4191739 YP_671707.1 CDS ECP_3835 NC_008253.1 4005143 4005958 D AraC family transcriptional regulator 4005143..4005958 Escherichia coli 536 4191740 YP_671708.1 CDS ECP_3836 NC_008253.1 4006163 4006492 D hypothetical protein 4006163..4006492 Escherichia coli 536 4191741 YP_671709.1 CDS ECP_3837 NC_008253.1 4007002 4007694 D transposase 4007002..4007694 Escherichia coli 536 4191742 YP_671710.1 CDS ECP_3838 NC_008253.1 4008032 4009264 R reverse transcriptase complement(4008032..4009264) Escherichia coli 536 4191743 YP_671711.1 CDS ECP_3839 NC_008253.1 4009478 4009678 D hypothetical protein 4009478..4009678 Escherichia coli 536 4191744 YP_671712.1 CDS ECP_3840 NC_008253.1 4009726 4011057 R transposase complement(4009726..4011057) Escherichia coli 536 4188413 YP_671713.1 CDS ECP_3841 NC_008253.1 4011116 4012138 D transposase 4011116..4012138 Escherichia coli 536 4188414 YP_671714.1 CDS ECP_3842 NC_008253.1 4012135 4012917 D transposase/IS protein 4012135..4012917 Escherichia coli 536 4188415 YP_671715.1 CDS ECP_3843 NC_008253.1 4012968 4014032 R transposase complement(4012968..4014032) Escherichia coli 536 4188416 YP_671716.1 CDS ECP_3844 NC_008253.1 4014160 4014429 R IS orf complement(4014160..4014429) Escherichia coli 536 4188417 YP_671717.1 CDS ECP_3845 NC_008253.1 4014426 4014806 R transposase complement(4014426..4014806) Escherichia coli 536 4188418 YP_671718.1 CDS ECP_3846 NC_008253.1 4015470 4015682 R hypothetical protein complement(4015470..4015682) Escherichia coli 536 4188419 YP_671719.1 CDS ECP_3847 NC_008253.1 4015823 4016038 R hypothetical protein complement(4015823..4016038) Escherichia coli 536 4188420 YP_671720.1 CDS ECP_3848 NC_008253.1 4016243 4016446 R hypothetical protein complement(4016243..4016446) Escherichia coli 536 4188421 YP_671721.1 CDS ECP_3849 NC_008253.1 4016473 4016790 R transposase complement(4016473..4016790) Escherichia coli 536 4188422 YP_671722.1 CDS ECP_3850 NC_008253.1 4016935 4017819 D hypothetical protein 4016935..4017819 Escherichia coli 536 4188423 YP_671723.1 CDS ECP_3851 NC_008253.1 4018022 4018702 D hypothetical protein 4018022..4018702 Escherichia coli 536 4188424 YP_671724.1 CDS ECP_3852 NC_008253.1 4018745 4019527 D hypothetical protein 4018745..4019527 Escherichia coli 536 4188425 YP_671725.1 CDS ECP_3853 NC_008253.1 4019533 4019766 D hypothetical protein 4019533..4019766 Escherichia coli 536 4188426 YP_671726.1 CDS ECP_3854 NC_008253.1 4019856 4020674 D hypothetical protein 4019856..4020674 Escherichia coli 536 4188427 YP_671727.1 CDS ECP_3855 NC_008253.1 4020766 4021251 D antirestriction protein 4020766..4021251 Escherichia coli 536 4188428 YP_671728.1 CDS ECP_3856 NC_008253.1 4021266 4021742 D radC-like protein 4021266..4021742 Escherichia coli 536 4188429 YP_671729.1 CDS ECP_3857 NC_008253.1 4021805 4022026 D hypothetical protein 4021805..4022026 Escherichia coli 536 4188430 YP_671730.1 CDS ECP_3858 NC_008253.1 4022100 4022468 D hypothetical protein 4022100..4022468 Escherichia coli 536 4188431 YP_671731.1 CDS ECP_3859 NC_008253.1 4022558 4022932 D hypothetical protein 4022558..4022932 Escherichia coli 536 4189048 YP_671732.1 CDS ECP_3860 NC_008253.1 4022929 4023408 D hypothetical protein 4022929..4023408 Escherichia coli 536 4189049 YP_671733.1 CDS ECP_3861 NC_008253.1 4023375 4023617 D hypothetical protein 4023375..4023617 Escherichia coli 536 4189050 YP_671734.1 CDS ECP_3862 NC_008253.1 4023701 4024546 D hypothetical protein 4023701..4024546 Escherichia coli 536 4189051 YP_671735.1 CDS ECP_3863 NC_008253.1 4024777 4024998 D hypothetical protein 4024777..4024998 Escherichia coli 536 4189052 YP_671736.1 CDS ECP_3864 NC_008253.1 4025139 4025507 D hypothetical protein 4025139..4025507 Escherichia coli 536 4189053 YP_671737.1 CDS ECP_3865 NC_008253.1 4025804 4026727 D hypothetical protein 4025804..4026727 Escherichia coli 536 4189054 YP_671738.1 CDS ECP_3866 NC_008253.1 4026731 4027549 R hypothetical protein complement(4026731..4027549) Escherichia coli 536 4189055 YP_671739.1 CDS ECP_3867 NC_008253.1 4027771 4028064 D hypothetical protein 4027771..4028064 Escherichia coli 536 4189056 YP_671740.2 CDS nepI NC_008253.1 4028105 4029295 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4028105..4029295) Escherichia coli 536 4189057 YP_671741.1 CDS ECP_3869 NC_008253.1 4029506 4029985 R hypothetical protein complement(4029506..4029985) Escherichia coli 536 4189058 YP_671742.1 CDS ECP_3870 NC_008253.1 4030011 4031423 R xanthine/uracil permease complement(4030011..4031423) Escherichia coli 536 4189059 YP_671743.1 CDS ECP_3871 NC_008253.1 4031520 4033286 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4031520..4033286 Escherichia coli 536 4189060 YP_671744.1 CDS uhpT NC_008253.1 4033332 4034723 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4033332..4034723) Escherichia coli 536 4189061 YP_671745.1 CDS ECP_3873 NC_008253.1 4034861 4036180 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4034861..4036180) Escherichia coli 536 4189062 YP_671746.1 CDS ECP_3874 NC_008253.1 4036190 4037692 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4036190..4037692) Escherichia coli 536 4189063 YP_671747.1 CDS ECP_3875 NC_008253.1 4037692 4038282 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4037692..4038282) Escherichia coli 536 4189064 YP_671748.1 CDS ECP_3876 NC_008253.1 4038594 4039556 D hypothetical protein 4038594..4039556 Escherichia coli 536 4189065 YP_671749.1 CDS ECP_3877 NC_008253.1 4039747 4040037 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4039747..4040037) Escherichia coli 536 4189066 YP_671750.1 CDS ECP_3878 NC_008253.1 4040041 4041729 R acetolactate synthase catalytic subunit complement(4040041..4041729) Escherichia coli 536 4189067 YP_671751.1 CDS emrD NC_008253.1 4042328 4043518 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4042328..4043518 Escherichia coli 536 4190479 YP_671752.1 CDS ECP_3880 NC_008253.1 4043526 4044023 R hypothetical protein complement(4043526..4044023) Escherichia coli 536 4190480 YP_671753.1 CDS ECP_3881 NC_008253.1 4044020 4044382 R hypothetical protein complement(4044020..4044382) Escherichia coli 536 4190481 YP_671754.1 CDS ECP_3882 NC_008253.1 4044372 4044779 R hypothetical protein complement(4044372..4044779) Escherichia coli 536 4190482 YP_671755.1 CDS ECP_3883 NC_008253.1 4044779 4046272 R sulfatase complement(4044779..4046272) Escherichia coli 536 4190483 YP_671756.1 CDS ECP_3884 NC_008253.1 4046269 4047984 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4046269..4047984) Escherichia coli 536 4190484 YP_671757.1 CDS ECP_3885 NC_008253.1 4048151 4049017 D transcriptional regulator YidL 4048151..4049017 Escherichia coli 536 4190485 YP_671758.1 CDS ECP_3886 NC_008253.1 4049107 4050792 R hypothetical protein complement(4049107..4050792) Escherichia coli 536 4190486 YP_671759.2 CDS ECP_3887 NC_008253.1 4050965 4051393 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4050965..4051393) Escherichia coli 536 4190487 YP_671760.1 CDS ECP_3888 NC_008253.1 4051505 4051918 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4051505..4051918) Escherichia coli 536 4190488 YP_671761.1 CDS ECP_3889 NC_008253.1 4052149 4052556 D hypothetical protein 4052149..4052556 Escherichia coli 536 4190489 YP_671762.1 CDS ECP_3890 NC_008253.1 4052560 4053774 R hypothetical protein complement(4052560..4053774) Escherichia coli 536 4190490 YP_671763.1 CDS ECP_3891 NC_008253.1 4053854 4054975 D FAD/NAD(P)-binding domain; oxidoreductase 4053854..4054975 Escherichia coli 536 4190491 YP_671764.1 CDS ECP_3892 NC_008253.1 4054936 4056273 R D-galactonate transporter complement(4054936..4056273) Escherichia coli 536 4190492 YP_671765.1 CDS ECP_3893 NC_008253.1 4056348 4057496 R bifunctional; galactonate dehydratase complement(4056348..4057496) Escherichia coli 536 4190493 YP_671766.1 CDS ECP_3894 NC_008253.1 4057493 4058110 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4057493..4058110) Escherichia coli 536 4190494 YP_671767.1 CDS ECP_3895 NC_008253.1 4058094 4058972 R 2-dehydro-3-deoxygalactonokinase complement(4058094..4058972) Escherichia coli 536 4190495 YP_671768.1 CDS ECP_3896 NC_008253.1 4058969 4059658 R galactonate operon transcriptional repressor complement(4058969..4059658) Escherichia coli 536 4190496 YP_671769.1 CDS ECP_3897 NC_008253.1 4059937 4060593 D hypothetical protein 4059937..4060593 Escherichia coli 536 4190497 YP_671770.1 CDS ECP_3898 NC_008253.1 4060637 4061449 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4060637..4061449) Escherichia coli 536 4188962 YP_671771.1 CDS ECP_3899 NC_008253.1 4061564 4061962 R hypothetical protein complement(4061564..4061962) Escherichia coli 536 4188963 YP_671772.1 CDS gyrB NC_008253.1 4062202 4064616 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4062202..4064616) Escherichia coli 536 4188964 YP_671773.1 CDS recF NC_008253.1 4064645 4065718 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4064645..4065718) Escherichia coli 536 4188965 YP_671774.1 CDS ECP_3902 NC_008253.1 4065718 4066818 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4065718..4066818) Escherichia coli 536 4188966 YP_671775.1 CDS ECP_3903 NC_008253.1 4066823 4068157 R chromosomal replication initiator protein DnaA complement(4066823..4068157) Escherichia coli 536 4188967 YP_671776.1 CDS ECP_3904 NC_008253.1 4068740 4068880 R hypothetical protein complement(4068740..4068880) Escherichia coli 536 4188968 YP_671777.1 CDS ECP_3905 NC_008253.1 4069023 4069349 D ribonuclease P protein component 4069023..4069349 Escherichia coli 536 4188969 YP_671778.1 CDS ECP_3906 NC_008253.1 4069573 4071219 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4069573..4071219 Escherichia coli 536 4188970 YP_671779.1 CDS trmE NC_008253.1 4071325 4072689 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4071325..4072689 Escherichia coli 536 4188971 YP_671780.1 CDS tnaA NC_008253.1 4073226 4074641 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4073226..4074641 Escherichia coli 536 4188972 YP_671781.1 CDS ECP_3909 NC_008253.1 4074733 4075980 D tryptophan transporter of low affinity; tryptophan permease TnaB 4074733..4075980 Escherichia coli 536 4188973 YP_671782.1 CDS ECP_3910 NC_008253.1 4076112 4077287 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4076112..4077287 Escherichia coli 536 4188974 YP_671783.1 CDS ECP_3911 NC_008253.1 4077334 4078221 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4077334..4078221 Escherichia coli 536 4188975 YP_671784.1 CDS ECP_3912 NC_008253.1 4078366 4079127 D hypothetical protein 4078366..4079127 Escherichia coli 536 4188976 YP_671785.1 CDS ECP_3913 NC_008253.1 4079149 4079715 D hypothetical protein 4079149..4079715 Escherichia coli 536 4188977 YP_671786.1 CDS ECP_3914 NC_008253.1 4079769 4081106 R membrane transport protein complement(4079769..4081106) Escherichia coli 536 4188978 YP_671787.1 CDS ECP_3915 NC_008253.1 4081273 4081938 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4081273..4081938 Escherichia coli 536 4188979 YP_671788.1 CDS ECP_3916 NC_008253.1 4082005 4082478 D might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4082005..4082478 Escherichia coli 536 4188980 YP_671789.1 CDS ECP_3917 NC_008253.1 4082560 4083282 R 6-phosphogluconolactonase complement(4082560..4083282) Escherichia coli 536 4188981 YP_671790.1 CDS ECP_3918 NC_008253.1 4083297 4084466 R hypothetical protein complement(4083297..4084466) Escherichia coli 536 4187754 YP_671791.1 CDS ECP_3919 NC_008253.1 4084493 4086109 R outer membrane protein YieC complement(4084493..4086109) Escherichia coli 536 4187755 YP_671792.1 CDS ECP_3920 NC_008253.1 4086195 4087589 R 6-phospho-beta-glucosidase complement(4086195..4087589) Escherichia coli 536 4187756 YP_671793.1 CDS ECP_3921 NC_008253.1 4087608 4089482 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; beta-glucoside-specific PTS system components IIABC complement(4087608..4089482) Escherichia coli 536 4187757 YP_671794.1 CDS ECP_3922 NC_008253.1 4089615 4090451 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4089615..4090451) Escherichia coli 536 4187758 YP_671795.1 CDS ECP_3923 NC_008253.1 4090737 4091462 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4090737..4091462) Escherichia coli 536 4187759 YP_671796.1 CDS ECP_3924 NC_008253.1 4091477 4092250 R phosphate transporter subunit complement(4091477..4092250) Escherichia coli 536 4187760 YP_671797.1 CDS pstA NC_008253.1 4092341 4093225 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4092341..4093225) Escherichia coli 536 4187761 YP_671798.1 CDS pstC NC_008253.1 4093231 4094190 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4093231..4094190) Escherichia coli 536 4187762 YP_671799.1 CDS ECP_3927 NC_008253.1 4094277 4095317 R phosphate ABC transporter substrate-binding protein complement(4094277..4095317) Escherichia coli 536 4187763 YP_671800.1 CDS ECP_3928 NC_008253.1 4095631 4097460 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4095631..4097460) Escherichia coli 536 4187764 YP_671801.1 CDS glmU NC_008253.1 4097621 4098991 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4097621..4098991) Escherichia coli 536 4187765 YP_671802.1 CDS atpC NC_008253.1 4099342 4099761 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(4099342..4099761) Escherichia coli 536 4187766 YP_671803.1 CDS ECP_3931 NC_008253.1 4099782 4101164 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(4099782..4101164) Escherichia coli 536 4187767 YP_671804.1 CDS ECP_3932 NC_008253.1 4101191 4102054 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(4101191..4102054) Escherichia coli 536 4187768 YP_671805.1 CDS ECP_3933 NC_008253.1 4102105 4103646 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(4102105..4103646) Escherichia coli 536 4187769 YP_671806.1 CDS ECP_3934 NC_008253.1 4103659 4104192 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(4103659..4104192) Escherichia coli 536 4187770 YP_671807.1 CDS ECP_3935 NC_008253.1 4104207 4104677 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(4104207..4104677) Escherichia coli 536 4187771 YP_671808.1 CDS ECP_3936 NC_008253.1 4104739 4104978 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(4104739..4104978) Escherichia coli 536 4187772 YP_671809.1 CDS ECP_3937 NC_008253.1 4105025 4105840 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(4105025..4105840) Escherichia coli 536 4189316 YP_671810.1 CDS ECP_3938 NC_008253.1 4105849 4106241 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4105849..4106241) Escherichia coli 536 4189317 YP_671811.1 CDS gidB NC_008253.1 4106846 4107469 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4106846..4107469) Escherichia coli 536 4189318 YP_671812.1 CDS ECP_3940 NC_008253.1 4107533 4109422 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4107533..4109422) Escherichia coli 536 4189319 YP_671813.1 CDS ECP_3941 NC_008253.1 4109801 4110244 R initiation of chromosome replication; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4109801..4110244) Escherichia coli 536 4189320 YP_671814.1 CDS ECP_3942 NC_008253.1 4110334 4110792 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4110334..4110792) Escherichia coli 536 4189321 YP_671815.1 CDS ECP_3943 NC_008253.1 4110944 4111936 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4110944..4111936 Escherichia coli 536 4189322 YP_671816.1 CDS yieM NC_008253.1 4111941 4113392 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4111941..4113392) Escherichia coli 536 4189323 YP_671817.1 CDS ECP_3945 NC_008253.1 4113386 4114882 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4113386..4114882) Escherichia coli 536 4189324 YP_671818.1 CDS trkD NC_008253.1 4115105 4116973 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4115105..4116973 Escherichia coli 536 4189325 YP_671819.2 CDS ECP_3947 NC_008253.1 4117140 4117559 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4117140..4117559 Escherichia coli 536 4189326 YP_671820.1 CDS ECP_3948 NC_008253.1 4117567 4119072 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4117567..4119072 Escherichia coli 536 4189327 YP_671821.1 CDS ECP_3951 NC_008253.1 4120068 4120958 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4120068..4120958 Escherichia coli 536 4189330 YP_671822.1 CDS ECP_3952 NC_008253.1 4121069 4122013 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4121069..4122013 Escherichia coli 536 4189331 YP_671823.1 CDS ECP_3953 NC_008253.1 4122017 4123009 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4122017..4123009 Escherichia coli 536 4189332 YP_671824.1 CDS ECP_3954 NC_008253.1 4122975 4124402 R transporter complement(4122975..4124402) Escherichia coli 536 4188605 YP_671825.1 CDS ECP_3955 NC_008253.1 4124425 4125117 R GntR family transcriptional regulator complement(4124425..4125117) Escherichia coli 536 4188606 YP_671826.1 CDS ECP_3959 NC_008253.1 4130918 4131757 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4130918..4131757) Escherichia coli 536 4188610 YP_671827.1 CDS ECP_3960 NC_008253.1 4131876 4132214 D hypothetical protein 4131876..4132214 Escherichia coli 536 4188611 YP_671828.1 CDS ECP_3961 NC_008253.1 4132239 4133759 R among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4132239..4133759) Escherichia coli 536 4188612 YP_671829.1 CDS ECP_3962 NC_008253.1 4134350 4135996 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4134350..4135996 Escherichia coli 536 4188613 YP_671830.1 CDS ECP_3963 NC_008253.1 4136276 4137205 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4136276..4137205 Escherichia coli 536 4188614 YP_671831.1 CDS ECP_3964 NC_008253.1 4137270 4139120 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4137270..4139120 Escherichia coli 536 4188615 YP_671832.1 CDS ECP_3965 NC_008253.1 4139120 4140667 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4139120..4140667 Escherichia coli 536 4188616 YP_671833.1 CDS ECP_3966 NC_008253.1 4140664 4141689 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4140664..4141689) Escherichia coli 536 4188617 YP_671834.1 CDS ECP_3967 NC_008253.1 4141704 4143179 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4141704..4143179 Escherichia coli 536 4188618 YP_671835.1 CDS ECP_3968 NC_008253.1 4143225 4143506 R peptidyl-prolyl cis-trans isomerase C complement(4143225..4143506) Escherichia coli 536 4188619 YP_671836.1 CDS ECP_3969 NC_008253.1 4143593 4145614 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4143593..4145614 Escherichia coli 536 4188620 YP_671837.1 CDS ECP_3972 NC_008253.1 4147282 4148547 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4147282..4148547) Escherichia coli 536 4188044 YP_671838.1 CDS trxA NC_008253.1 4148573 4149007 D thioredoxin 4148573..4149007 Escherichia coli 536 4188045 YP_671839.1 CDS rho NC_008253.1 4149262 4150593 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4149262..4150593 Escherichia coli 536 4188046 YP_671840.1 CDS ECP_3975 NC_008253.1 4150833 4151936 D undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 4150833..4151936 Escherichia coli 536 4188047 YP_671841.1 CDS ECP_3976 NC_008253.1 4151948 4152994 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4151948..4152994 Escherichia coli 536 4188048 YP_671842.1 CDS ECP_3977 NC_008253.1 4153050 4154180 D UDP-N-acetylglucosamine 2-epimerase 4153050..4154180 Escherichia coli 536 4188049 YP_671843.1 CDS ECP_3978 NC_008253.1 4154415 4155440 D UDP-N-acetyl-D-mannosamine dehydrogenase 4154415..4155440 Escherichia coli 536 4188050 YP_671844.1 CDS ECP_3979 NC_008253.1 4155440 4156507 D dTDP-glucose 4,6-dehydratase 4155440..4156507 Escherichia coli 536 4188051 YP_671845.1 CDS ECP_3980 NC_008253.1 4156526 4157407 D glucose-1-phosphate thymidylyltransferase 4156526..4157407 Escherichia coli 536 4188052 YP_671846.1 CDS ECP_3981 NC_008253.1 4157385 4158059 D TDP-fucosamine acetyltransferase 4157385..4158059 Escherichia coli 536 4188053 YP_671847.1 CDS ECP_3982 NC_008253.1 4158064 4159194 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4158064..4159194 Escherichia coli 536 4188054 YP_671848.1 CDS ECP_3983 NC_008253.1 4159196 4160446 D lipopolysaccharide biosynthesis protein WzxE 4159196..4160446 Escherichia coli 536 4188055 YP_671849.1 CDS ECP_3984 NC_008253.1 4160443 4161522 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4160443..4161522 Escherichia coli 536 4188056 YP_671850.1 CDS ECP_3985 NC_008253.1 4161519 4162871 D enterobacterial common antigen polymerase; common antigen polymerase 4161519..4162871 Escherichia coli 536 4188057 YP_671851.1 CDS ECP_3986 NC_008253.1 4162874 4163614 D UDP-N-acetyl-D-mannosaminuronic acid transferase 4162874..4163614 Escherichia coli 536 4188058 YP_671852.1 CDS ECP_3987 NC_008253.1 4163805 4165190 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4163805..4165190 Escherichia coli 536 4190963 YP_671853.1 CDS ECP_3992 NC_008253.1 4165876 4167111 D arylsulfatase regulatory protein 4165876..4167111 Escherichia coli 536 4190968 YP_671854.1 CDS ECP_3993 NC_008253.1 4167202 4168857 R arylsulfatase complement(4167202..4168857) Escherichia coli 536 4190969 YP_671855.1 CDS ECP_3994 NC_008253.1 4169536 4170732 R protoheme IX biogenesis protein complement(4169536..4170732) Escherichia coli 536 4190970 YP_671856.1 CDS ECP_3995 NC_008253.1 4170735 4171934 R uroporphyrinogen III C-methyltransferase complement(4170735..4171934) Escherichia coli 536 4190971 YP_671857.1 CDS hemD NC_008253.1 4171956 4172696 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4171956..4172696) Escherichia coli 536 4190972 YP_671858.1 CDS hemC NC_008253.1 4172693 4173655 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4172693..4173655) Escherichia coli 536 4190973 YP_671859.1 CDS ECP_3998 NC_008253.1 4173787 4174116 R hypothetical protein complement(4173787..4174116) Escherichia coli 536 4190974 YP_671860.2 CDS cyaA NC_008253.1 4174021 4176567 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4174021..4176567 Escherichia coli 536 4190975 YP_671861.1 CDS cyaY NC_008253.1 4176607 4176927 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4176607..4176927) Escherichia coli 536 4190976 YP_671862.1 CDS ECP_4001 NC_008253.1 4176975 4177208 R hypothetical protein complement(4176975..4177208) Escherichia coli 536 4190977 YP_671863.1 CDS ECP_4002 NC_008253.1 4177397 4177600 D hypothetical protein 4177397..4177600 Escherichia coli 536 4190780 YP_671864.1 CDS dapF NC_008253.1 4177637 4178461 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4177637..4178461 Escherichia coli 536 4190781 YP_671865.1 CDS ECP_4004 NC_008253.1 4178458 4179165 D hypothetical protein 4178458..4179165 Escherichia coli 536 4190782 YP_671866.1 CDS xerC NC_008253.1 4179162 4180058 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4179162..4180058 Escherichia coli 536 4190783 YP_671867.1 CDS ECP_4006 NC_008253.1 4180058 4180774 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4180058..4180774 Escherichia coli 536 4190784 YP_671868.1 CDS uvrD NC_008253.1 4180858 4183020 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4180858..4183020 Escherichia coli 536 4190785 YP_671869.1 CDS ECP_4008 NC_008253.1 4183065 4183967 R hypothetical protein complement(4183065..4183967) Escherichia coli 536 4190786 YP_671870.1 CDS ECP_4009 NC_008253.1 4184050 4184814 R hypothetical protein complement(4184050..4184814) Escherichia coli 536 4190787 YP_671871.1 CDS ECP_4010 NC_008253.1 4185184 4186134 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4185184..4186134 Escherichia coli 536 4190788 YP_671872.1 CDS ECP_4011 NC_008253.1 4186170 4186667 R hypothetical protein complement(4186170..4186667) Escherichia coli 536 4190789 YP_671873.1 CDS ECP_4012 NC_008253.1 4186664 4187512 R hypothetical protein complement(4186664..4187512) Escherichia coli 536 4190790 YP_671874.1 CDS ECP_4013 NC_008253.1 4187822 4188712 R hypothetical protein complement(4187822..4188712) Escherichia coli 536 4190791 YP_671875.1 CDS ECP_4014 NC_008253.1 4188764 4189231 R hypothetical protein complement(4188764..4189231) Escherichia coli 536 4190792 YP_671876.1 CDS ECP_4015 NC_008253.1 4189395 4190264 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4189395..4190264 Escherichia coli 536 4190793 YP_671877.1 CDS ECP_4016 NC_008253.1 4190389 4192218 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4190389..4192218 Escherichia coli 536 4190794 YP_671878.1 CDS ECP_4017 NC_008253.1 4192282 4192902 D threonine efflux system 4192282..4192902 Escherichia coli 536 4190795 YP_671879.1 CDS rhtB NC_008253.1 4192963 4193583 R homoserine/homoserine lactone efflux protein complement(4192963..4193583) Escherichia coli 536 4190796 YP_671880.1 CDS ECP_4019 NC_008253.1 4193694 4194716 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4193694..4194716 Escherichia coli 536 4190797 YP_671881.1 CDS ECP_4020 NC_008253.1 4194724 4195524 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4194724..4195524 Escherichia coli 536 4190798 YP_671882.1 CDS ECP_4021 NC_008253.1 4195600 4196499 D hypothetical protein 4195600..4196499 Escherichia coli 536 4190799 YP_671883.1 CDS ECP_4022 NC_008253.1 4196387 4197340 R LysR family transcriptional regulator complement(4196387..4197340) Escherichia coli 536 4188753 YP_671884.1 CDS ECP_4023 NC_008253.1 4197458 4199719 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4197458..4199719 Escherichia coli 536 4188754 YP_671885.1 CDS ECP_4024 NC_008253.1 4199888 4200133 R hypothetical protein complement(4199888..4200133) Escherichia coli 536 4188755 YP_671886.1 CDS ECP_4025 NC_008253.1 4200208 4200465 R hypothetical protein complement(4200208..4200465) Escherichia coli 536 4188756 YP_671887.1 CDS ECP_4026 NC_008253.1 4200462 4201595 R hypothetical protein complement(4200462..4201595) Escherichia coli 536 4188757 YP_671888.1 CDS ECP_4027 NC_008253.1 4202080 4202637 D hypothetical protein 4202080..4202637 Escherichia coli 536 4188758 YP_671889.1 CDS ECP_4028 NC_008253.1 4202679 4204187 D PTS system, glucose-specific IIBC component 4202679..4204187 Escherichia coli 536 4188759 YP_671890.1 CDS ECP_4029 NC_008253.1 4204238 4206235 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4204238..4206235 Escherichia coli 536 4188760 YP_671891.1 CDS ECP_4030 NC_008253.1 4206265 4207110 R transcriptional regulator complement(4206265..4207110) Escherichia coli 536 4188761 YP_671892.1 CDS ECP_4031 NC_008253.1 4207311 4208216 R LysR family transcriptional regulator complement(4207311..4208216) Escherichia coli 536 4188762 YP_671893.1 CDS ECP_4032 NC_008253.1 4208294 4209517 R permease complement(4208294..4209517) Escherichia coli 536 4188763 YP_671894.1 CDS ECP_4033 NC_008253.1 4209543 4209932 R hypothetical protein complement(4209543..4209932) Escherichia coli 536 4188764 YP_671895.1 CDS ECP_4034 NC_008253.1 4209949 4210905 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4209949..4210905) Escherichia coli 536 4188765 YP_671896.1 CDS ECP_4035 NC_008253.1 4210898 4212322 R hypothetical protein complement(4210898..4212322) Escherichia coli 536 4188766 YP_671897.1 CDS ECP_4036 NC_008253.1 4212319 4213878 R YahF/FdrA-like protein complement(4212319..4213878) Escherichia coli 536 4188767 YP_671898.1 CDS ECP_4037 NC_008253.1 4213973 4214833 R hypothetical protein complement(4213973..4214833) Escherichia coli 536 4188768 YP_671899.1 CDS ECP_4038 NC_008253.1 4214839 4215507 R isochorismatase YcdL complement(4214839..4215507) Escherichia coli 536 4188769 YP_671900.1 CDS ECP_4039 NC_008253.1 4215764 4216573 R carboxymethylenebutenolidase complement(4215764..4216573) Escherichia coli 536 4188770 YP_671901.1 CDS ECP_4040 NC_008253.1 4216835 4217599 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4216835..4217599 Escherichia coli 536 4188771 YP_671902.1 CDS ECP_4041 NC_008253.1 4217634 4219124 R hypothetical protein complement(4217634..4219124) Escherichia coli 536 4187907 YP_671903.1 CDS ECP_4042 NC_008253.1 4219137 4219643 R hypothetical protein complement(4219137..4219643) Escherichia coli 536 4187908 YP_671904.1 CDS ECP_4043 NC_008253.1 4219660 4220634 R hypothetical protein complement(4219660..4220634) Escherichia coli 536 4187909 YP_671905.1 CDS ECP_4044 NC_008253.1 4220659 4221288 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4220659..4221288) Escherichia coli 536 4187910 YP_671906.1 CDS ECP_4045 NC_008253.1 4221278 4222282 R 2-oxo-3-deoxygalactonate kinase complement(4221278..4222282) Escherichia coli 536 4187911 YP_671907.1 CDS ECP_4046 NC_008253.1 4222306 4223073 R transcriptional regulator complement(4222306..4223073) Escherichia coli 536 4187912 YP_671908.1 CDS ECP_4047 NC_008253.1 4223290 4224717 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4223290..4224717 Escherichia coli 536 4187913 YP_671909.1 CDS ubiE NC_008253.1 4224812 4225567 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4224812..4225567 Escherichia coli 536 4187914 YP_671910.1 CDS ECP_4049 NC_008253.1 4225581 4226186 D hypothetical protein 4225581..4226186 Escherichia coli 536 4187915 YP_671911.1 CDS ubiB NC_008253.1 4226183 4227823 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4226183..4227823 Escherichia coli 536 4187916 YP_671912.1 CDS tatA NC_008253.1 4227902 4228171 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4227902..4228171 Escherichia coli 536 4187917 YP_671913.1 CDS ECP_4052 NC_008253.1 4228175 4228690 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4228175..4228690 Escherichia coli 536 4187918 YP_671914.1 CDS ECP_4053 NC_008253.1 4228693 4229469 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4228693..4229469 Escherichia coli 536 4187919 YP_671915.1 CDS ECP_4054 NC_008253.1 4229499 4230293 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4229499..4230293 Escherichia coli 536 4187920 YP_671916.1 CDS rfaH NC_008253.1 4230290 4230778 R transcriptional activator RfaH complement(4230290..4230778) Escherichia coli 536 4187921 YP_671917.1 CDS ECP_4056 NC_008253.1 4230945 4232441 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4230945..4232441 Escherichia coli 536 4187922 YP_671918.1 CDS fre NC_008253.1 4232487 4233188 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4232487..4233188 Escherichia coli 536 4187923 YP_671919.1 CDS fadA NC_008253.1 4233470 4234633 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4233470..4234633) Escherichia coli 536 4187924 YP_671920.1 CDS fadB NC_008253.1 4234643 4236832 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4234643..4236832) Escherichia coli 536 4187925 YP_671921.1 CDS ECP_4060 NC_008253.1 4237022 4238353 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4237022..4238353 Escherichia coli 536 4187926 YP_671922.1 CDS ECP_4061 NC_008253.1 4238350 4238967 D hypothetical protein 4238350..4238967 Escherichia coli 536 4187700 YP_671923.1 CDS ECP_4062 NC_008253.1 4239006 4240457 D potassium transporter 4239006..4240457 Escherichia coli 536 4187701 YP_671924.1 CDS hemG NC_008253.1 4240469 4241014 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4240469..4241014 Escherichia coli 536 4187702 YP_671925.1 CDS ECP_4066 NC_008253.1 4246599 4247126 R molybdopterin-guanine dinucleotide biosynthesis protein B complement(4246599..4247126) Escherichia coli 536 4187705 YP_671926.1 CDS mobA NC_008253.1 4247108 4247683 R Links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A complement(4247108..4247683) Escherichia coli 536 4187706 YP_671927.1 CDS ECP_4068 NC_008253.1 4247762 4248031 D hypothetical protein 4247762..4248031 Escherichia coli 536 4187707 YP_671928.1 CDS ECP_4069 NC_008253.1 4248108 4249094 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4248108..4249094 Escherichia coli 536 4187708 YP_671929.1 CDS ECP_4070 NC_008253.1 4249111 4249737 D protein disulfide isomerase I 4249111..4249737 Escherichia coli 536 4187709 YP_671930.1 CDS ECP_4071 NC_008253.1 4249892 4251322 D hypothetical protein 4249892..4251322 Escherichia coli 536 4187710 YP_671931.1 CDS ECP_4072 NC_008253.1 4251363 4252295 R acyltransferase complement(4251363..4252295) Escherichia coli 536 4187711 YP_671932.1 CDS ECP_4073 NC_008253.1 4252415 4252600 R hypothetical protein complement(4252415..4252600) Escherichia coli 536 4187712 YP_671933.1 CDS ECP_4074 NC_008253.1 4252659 4255445 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4252659..4255445 Escherichia coli 536 4187713 YP_671934.1 CDS ECP_4075 NC_008253.1 4255827 4256420 R GTP-binding protein EngB complement(4255827..4256420) Escherichia coli 536 4187714 YP_671935.1 CDS ECP_4076 NC_008253.1 4257042 4257551 D hypothetical protein 4257042..4257551 Escherichia coli 536 4187715 YP_671936.1 CDS ECP_4077 NC_008253.1 4257740 4259113 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4257740..4259113 Escherichia coli 536 4187716 YP_671937.1 CDS ECP_4078 NC_008253.1 4259346 4259456 R hypothetical protein complement(4259346..4259456) Escherichia coli 536 4187206 YP_671938.1 CDS glnG NC_008253.1 4259568 4260977 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4259568..4260977) Escherichia coli 536 4187207 YP_671939.1 CDS glnL NC_008253.1 4260989 4262038 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4260989..4262038) Escherichia coli 536 4187208 YP_671940.1 CDS glnA NC_008253.1 4262212 4263621 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4262212..4263621) Escherichia coli 536 4187209 YP_671941.1 CDS ECP_4082 NC_008253.1 4263994 4265817 D GTP-binding protein 4263994..4265817 Escherichia coli 536 4187210 YP_671942.1 CDS ECP_4083 NC_008253.1 4266034 4266744 D transcriptional regulator YihL 4266034..4266744 Escherichia coli 536 4187211 YP_671943.1 CDS ECP_4084 NC_008253.1 4266752 4267732 D hypothetical protein 4266752..4267732 Escherichia coli 536 4187212 YP_671944.1 CDS ECP_4085 NC_008253.1 4267834 4269099 D membrane protein YihN 4267834..4269099 Escherichia coli 536 4187213 YP_671945.1 CDS ECP_4086 NC_008253.1 4269159 4269947 R transcriptional regulator YihW complement(4269159..4269947) Escherichia coli 536 4187214 YP_671946.1 CDS ECP_4087 NC_008253.1 4269987 4270883 R sugar kinase complement(4269987..4270883) Escherichia coli 536 4187215 YP_671947.1 CDS ECP_4088 NC_008253.1 4271056 4271934 D oxidoreductase YihU 4271056..4271934 Escherichia coli 536 4187216 YP_671948.1 CDS ECP_4089 NC_008253.1 4271959 4272846 D hypothetical protein 4271959..4272846 Escherichia coli 536 4187217 YP_671949.1 CDS ECP_4090 NC_008253.1 4272879 4273889 D dehydrogenase 4272879..4273889 Escherichia coli 536 4187218 YP_671950.1 CDS ECP_4091 NC_008253.1 4273959 4275392 D hypothetical protein 4273959..4275392 Escherichia coli 536 4187219 YP_671951.1 CDS ECP_4092 NC_008253.1 4275491 4276840 D transmembrane transport protein 4275491..4276840 Escherichia coli 536 4187220 YP_671952.1 CDS ECP_4093 NC_008253.1 4276830 4277717 D aldose-1-epimerase 4276830..4277717 Escherichia coli 536 4187221 YP_671953.1 CDS ECP_4094 NC_008253.1 4277858 4278457 D phosphatase 4277858..4278457 Escherichia coli 536 4187222 YP_671954.1 CDS rbn NC_008253.1 4278451 4279323 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4278451..4279323 Escherichia coli 536 4187223 YP_671955.1 CDS ECP_4096 NC_008253.1 4279320 4279757 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4279320..4279757 Escherichia coli 536 4187224 YP_671956.1 CDS ECP_4097 NC_008253.1 4279754 4280743 D acetyltransferase 4279754..4280743 Escherichia coli 536 4187225 YP_671957.1 CDS ECP_4098 NC_008253.1 4280807 4281727 R acetyl-hydrolase complement(4280807..4281727) Escherichia coli 536 4189718 YP_671958.1 CDS ECP_4099 NC_008253.1 4282094 4282255 D hypothetical protein 4282094..4282255 Escherichia coli 536 4189719 YP_671959.1 CDS ECP_4100 NC_008253.1 4282256 4282546 D hypothetical protein 4282256..4282546 Escherichia coli 536 4189720 YP_671960.1 CDS ECP_4101 NC_008253.1 4282954 4283121 R hypothetical protein complement(4282954..4283121) Escherichia coli 536 4189721 YP_671961.1 CDS ECP_4102 NC_008253.1 4283151 4283369 D hypothetical protein 4283151..4283369 Escherichia coli 536 4189722 YP_671962.1 CDS ECP_4103 NC_008253.1 4283584 4284513 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4283584..4284513) Escherichia coli 536 4189723 YP_671963.1 CDS ECP_4104 NC_008253.1 4284510 4285145 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4284510..4285145) Escherichia coli 536 4189724 YP_671964.1 CDS ECP_4105 NC_008253.1 4285142 4286044 R formate dehydrogenase-O, iron-sulfur subunit complement(4285142..4286044) Escherichia coli 536 4189725 YP_671965.1 CDS ECP_4108 NC_008253.1 4289301 4290134 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4289301..4290134 Escherichia coli 536 4189728 YP_671966.1 CDS ECP_4109 NC_008253.1 4290184 4290846 D hypothetical protein 4290184..4290846 Escherichia coli 536 4189729 YP_671967.1 CDS ECP_4110 NC_008253.1 4291267 4292661 D hypothetical protein 4291267..4292661 Escherichia coli 536 4189730 YP_671968.1 CDS ECP_4111 NC_008253.1 4292702 4293016 R hypothetical protein complement(4292702..4293016) Escherichia coli 536 4189731 YP_671969.1 CDS ECP_4112 NC_008253.1 4293026 4293850 R rhamnulose-1-phosphate aldolase complement(4293026..4293850) Escherichia coli 536 4189732 YP_671970.1 CDS ECP_4113 NC_008253.1 4294025 4295284 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4294025..4295284) Escherichia coli 536 4189733 YP_671971.1 CDS rhaB NC_008253.1 4295281 4296750 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4295281..4296750) Escherichia coli 536 4189734 YP_671972.1 CDS ECP_4115 NC_008253.1 4297038 4297874 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4297038..4297874 Escherichia coli 536 4191054 YP_671973.1 CDS ECP_4116 NC_008253.1 4297858 4298796 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4297858..4298796 Escherichia coli 536 4191055 YP_671974.1 CDS ECP_4117 NC_008253.1 4298793 4299827 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4298793..4299827) Escherichia coli 536 4191056 YP_671975.1 CDS ECP_4118 NC_008253.1 4300113 4300733 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4300113..4300733 Escherichia coli 536 4191057 YP_671976.1 CDS ECP_4119 NC_008253.1 4300993 4301976 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4300993..4301976 Escherichia coli 536 4191058 YP_671977.1 CDS ECP_4120 NC_008253.1 4302125 4302799 D hypothetical protein 4302125..4302799 Escherichia coli 536 4191059 YP_671978.1 CDS cpxA NC_008253.1 4302971 4304344 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4302971..4304344) Escherichia coli 536 4191060 YP_671979.1 CDS ECP_4122 NC_008253.1 4304341 4305039 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4304341..4305039) Escherichia coli 536 4191061 YP_671980.1 CDS cpxP NC_008253.1 4305189 4305689 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4305189..4305689 Escherichia coli 536 4191062 YP_671981.1 CDS fieF NC_008253.1 4305838 4306740 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4305838..4306740 Escherichia coli 536 4191063 YP_671982.1 CDS ECP_4125 NC_008253.1 4306921 4307883 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4306921..4307883 Escherichia coli 536 4191064 YP_671983.1 CDS ECP_4126 NC_008253.1 4308203 4309192 D sulfate transporter subunit 4308203..4309192 Escherichia coli 536 4191065 YP_671984.1 CDS ECP_4127 NC_008253.1 4309329 4310054 D CDP-diacylglycerol pyrophosphatase 4309329..4310054 Escherichia coli 536 4191066 YP_671985.1 CDS tpiA NC_008253.1 4310109 4310876 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4310109..4310876) Escherichia coli 536 4191067 YP_671986.1 CDS ECP_4129 NC_008253.1 4310984 4311583 R hypothetical protein complement(4310984..4311583) Escherichia coli 536 4191068 YP_671987.1 CDS ECP_4130 NC_008253.1 4311684 4312124 D hypothetical protein 4311684..4312124 Escherichia coli 536 4191069 YP_671988.1 CDS ECP_4131 NC_008253.1 4312335 4312634 D hypothetical protein 4312335..4312634 Escherichia coli 536 4191070 YP_671989.1 CDS ECP_4132 NC_008253.1 4312661 4313089 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4312661..4313089 Escherichia coli 536 4191071 YP_671990.1 CDS ECP_4133 NC_008253.1 4313094 4313840 R ferredoxin-NADP reductase complement(4313094..4313840) Escherichia coli 536 4191072 YP_671991.1 CDS glpX NC_008253.1 4313937 4314947 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4313937..4314947) Escherichia coli 536 4188316 YP_671992.1 CDS glpK NC_008253.1 4315118 4316626 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4315118..4316626) Escherichia coli 536 4188317 YP_671993.1 CDS ECP_4136 NC_008253.1 4316649 4317494 R glycerol uptake facilitator protein complement(4316649..4317494) Escherichia coli 536 4188318 YP_671994.1 CDS ECP_4137 NC_008253.1 4317925 4318164 D hypothetical protein 4317925..4318164 Escherichia coli 536 4188319 YP_671995.1 CDS ECP_4138 NC_008253.1 4318249 4318734 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4318249..4318734) Escherichia coli 536 4188320 YP_671996.1 CDS ECP_4139 NC_008253.1 4318827 4319753 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4318827..4319753) Escherichia coli 536 4188321 YP_671997.1 CDS hslU NC_008253.1 4319820 4321151 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4319820..4321151) Escherichia coli 536 4188322 YP_671998.1 CDS ECP_4141 NC_008253.1 4321161 4321691 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4321161..4321691) Escherichia coli 536 4188323 YP_671999.1 CDS ECP_4142 NC_008253.1 4321784 4322743 R cell division protein FtsN complement(4321784..4322743) Escherichia coli 536 4188324 YP_672000.1 CDS ECP_4143 NC_008253.1 4322835 4323860 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4322835..4323860) Escherichia coli 536 4188325 YP_672001.1 CDS ECP_4144 NC_008253.1 4324016 4326214 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4324016..4326214) Escherichia coli 536 4188326 YP_672002.1 CDS rpmE NC_008253.1 4326417 4326629 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4326417..4326629 Escherichia coli 536 4188327 YP_672003.1 CDS ECP_4146 NC_008253.1 4326690 4327298 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4326690..4327298) Escherichia coli 536 4188328 YP_672004.1 CDS ECP_4147 NC_008253.1 4327358 4327675 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4327358..4327675) Escherichia coli 536 4188329 YP_672005.1 CDS ECP_4148 NC_008253.1 4327952 4329112 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4327952..4329112 Escherichia coli 536 4188330 YP_672006.1 CDS metL NC_008253.1 4329115 4331547 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4329115..4331547 Escherichia coli 536 4188331 YP_672007.1 CDS ECP_4150 NC_008253.1 4331765 4332523 R nucleoside-specific channel-forming protein tsx complement(4331765..4332523) Escherichia coli 536 4188332 YP_672008.1 CDS ECP_4151 NC_008253.1 4332702 4334321 R 5'-nucleotidase complement(4332702..4334321) Escherichia coli 536 4188333 YP_672009.1 CDS ECP_4152 NC_008253.1 4334362 4335912 R 5'-nucleotidase complement(4334362..4335912) Escherichia coli 536 4188334 YP_672010.1 CDS ECP_4153 NC_008253.1 4336145 4337269 R hypothetical protein complement(4336145..4337269) Escherichia coli 536 4188335 YP_672011.1 CDS ECP_4154 NC_008253.1 4337402 4338955 D 5'-nucleotidase 4337402..4338955 Escherichia coli 536 4189182 YP_672012.1 CDS metF NC_008253.1 4339337 4340227 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4339337..4340227 Escherichia coli 536 4189183 YP_672013.1 CDS ECP_4156 NC_008253.1 4340556 4342736 D peroxidase/catalase HPI 4340556..4342736 Escherichia coli 536 4189184 YP_672014.1 CDS ECP_4157 NC_008253.1 4342764 4343735 D transporter 4342764..4343735 Escherichia coli 536 4189185 YP_672015.1 CDS ECP_4158 NC_008253.1 4343762 4344379 R hypothetical protein complement(4343762..4344379) Escherichia coli 536 4189186 YP_672016.1 CDS gldA NC_008253.1 4344655 4345758 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4344655..4345758) Escherichia coli 536 4189187 YP_672017.1 CDS ECP_4160 NC_008253.1 4345769 4346431 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4345769..4346431) Escherichia coli 536 4189188 YP_672018.1 CDS ECP_4161 NC_008253.1 4346443 4348944 R phosphoenolpyruvate-protein phosphotransferase PtsA complement(4346443..4348944) Escherichia coli 536 4189189 YP_672019.1 CDS ECP_4162 NC_008253.1 4349253 4350332 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4349253..4350332 Escherichia coli 536 4189190 YP_672020.1 CDS ECP_4163 NC_008253.1 4350347 4350667 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; fructose-like phosphotransferase EIIB subunit 2 4350347..4350667 Escherichia coli 536 4189191 YP_672021.1 CDS pflD NC_008253.1 4350718 4353015 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4350718..4353015 Escherichia coli 536 4189192 YP_672022.1 CDS ECP_4165 NC_008253.1 4352981 4353859 D pyruvate formate lyase II activase 4352981..4353859 Escherichia coli 536 4189193 YP_672023.1 CDS ECP_4166 NC_008253.1 4353861 4354202 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4353861..4354202 Escherichia coli 536 4189194 YP_672024.1 CDS ECP_4167 NC_008253.1 4354189 4355040 R transcriptional regulator YijO complement(4354189..4355040) Escherichia coli 536 4189195 YP_672025.1 CDS ECP_4168 NC_008253.1 4355266 4356999 R hypothetical protein complement(4355266..4356999) Escherichia coli 536 4189196 YP_672026.1 CDS ECP_4169 NC_008253.1 4357182 4359833 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4357182..4359833) Escherichia coli 536 4189197 YP_672027.1 CDS ECP_4170 NC_008253.1 4360135 4361286 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4360135..4361286) Escherichia coli 536 4189198 YP_672028.1 CDS argC NC_008253.1 4361440 4362444 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4361440..4362444 Escherichia coli 536 4189199 YP_672029.1 CDS ECP_4172 NC_008253.1 4362455 4363228 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4362455..4363228 Escherichia coli 536 4189200 YP_672030.1 CDS ECP_4173 NC_008253.1 4363289 4364662 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4363289..4364662 Escherichia coli 536 4189201 YP_672031.1 CDS ECP_4174 NC_008253.1 4365100 4366374 D starvation sensing protein RspA 4365100..4366374 Escherichia coli 536 4189202 YP_672032.1 CDS ECP_4175 NC_008253.1 4366441 4367724 D transporter 4366441..4367724 Escherichia coli 536 4189203 YP_672033.1 CDS ECP_4176 NC_008253.1 4367976 4368893 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4367976..4368893 Escherichia coli 536 4189204 YP_672034.1 CDS ECP_4177 NC_008253.1 4368876 4370276 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4368876..4370276) Escherichia coli 536 4189205 YP_672035.1 CDS ECP_4178 NC_008253.1 4370606 4371772 D hippuricase; hippurate hydrolase 4370606..4371772 Escherichia coli 536 4189206 YP_672036.1 CDS ECP_4179 NC_008253.1 4371815 4373131 D transporter transmembrane protein 4371815..4373131 Escherichia coli 536 4189207 YP_672037.1 CDS ECP_4180 NC_008253.1 4373181 4373885 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4373181..4373885 Escherichia coli 536 4189208 YP_672038.1 CDS ECP_4181 NC_008253.1 4373885 4374244 D hypothetical protein 4373885..4374244 Escherichia coli 536 4189209 YP_672039.1 CDS ECP_4182 NC_008253.1 4374284 4375384 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4374284..4375384) Escherichia coli 536 4189210 YP_672040.2 CDS btuB NC_008253.1 4375753 4377597 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4375753..4377597 Escherichia coli 536 4189211 YP_672041.2 CDS ECP_4184 NC_008253.1 4377542 4378399 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4377542..4378399 Escherichia coli 536 4189212 YP_672042.1 CDS murB NC_008253.1 4384015 4385043 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4384015..4385043 Escherichia coli 536 4189214 YP_672043.1 CDS ECP_4187 NC_008253.1 4385040 4386005 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4385040..4386005 Escherichia coli 536 4189215 YP_672044.1 CDS ECP_4188 NC_008253.1 4386034 4387005 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4386034..4387005) Escherichia coli 536 4189216 YP_672045.1 CDS ECP_4193 NC_008253.1 4387902 4389086 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4387902..4389086 Escherichia coli 536 4188246 YP_672046.1 CDS secE NC_008253.1 4389316 4389699 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4389316..4389699 Escherichia coli 536 4188247 YP_672047.1 CDS nusG NC_008253.1 4389701 4390246 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4389701..4390246 Escherichia coli 536 4188248 YP_672048.1 CDS rplK NC_008253.1 4390405 4390833 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4390405..4390833 Escherichia coli 536 4188249 YP_672049.1 CDS rplA NC_008253.1 4390837 4391541 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4390837..4391541 Escherichia coli 536 4188250 YP_672050.1 CDS rplJ NC_008253.1 4391833 4392330 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4391833..4392330 Escherichia coli 536 4188251 YP_672051.1 CDS rplL NC_008253.1 4392397 4392762 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4392397..4392762 Escherichia coli 536 4188252 YP_672052.1 CDS rpoB NC_008253.1 4393082 4397110 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4393082..4397110 Escherichia coli 536 4188253 YP_672053.1 CDS ECP_4201 NC_008253.1 4397187 4401410 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4397187..4401410 Escherichia coli 536 4188254 YP_672054.1 CDS thiH NC_008253.1 4401652 4402785 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4401652..4402785) Escherichia coli 536 4188255 YP_672055.1 CDS thiG NC_008253.1 4402782 4403552 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4402782..4403552) Escherichia coli 536 4188256 YP_672056.1 CDS ECP_4204 NC_008253.1 4403554 4403754 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4403554..4403754) Escherichia coli 536 4188257 YP_672057.1 CDS ECP_4205 NC_008253.1 4403738 4404493 R adenylyltransferase complement(4403738..4404493) Escherichia coli 536 4188258 YP_672058.1 CDS ECP_4206 NC_008253.1 4404486 4405121 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4404486..4405121) Escherichia coli 536 4188259 YP_672059.1 CDS ECP_4207 NC_008253.1 4405121 4407016 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4405121..4407016) Escherichia coli 536 4188679 YP_672060.1 CDS ECP_4208 NC_008253.1 4407249 4407725 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4407249..4407725) Escherichia coli 536 4188680 YP_672061.1 CDS nudC NC_008253.1 4407820 4408593 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4407820..4408593 Escherichia coli 536 4188681 YP_672062.1 CDS hemE NC_008253.1 4408633 4409697 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4408633..4409697 Escherichia coli 536 4188682 YP_672063.1 CDS ECP_4211 NC_008253.1 4409707 4410378 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4409707..4410378 Escherichia coli 536 4188683 YP_672064.1 CDS ECP_4212 NC_008253.1 4410421 4411011 D hypothetical protein 4410421..4411011 Escherichia coli 536 4188684 YP_672065.1 CDS ECP_4213 NC_008253.1 4411198 4411470 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4411198..4411470 Escherichia coli 536 4188685 YP_672066.1 CDS ECP_4214 NC_008253.1 4411543 4412178 D hypothetical protein 4411543..4412178 Escherichia coli 536 4188686 YP_672067.1 CDS zraP NC_008253.1 4412180 4412599 R zinc resistance protein complement(4412180..4412599) Escherichia coli 536 4188687 YP_672068.1 CDS ECP_4216 NC_008253.1 4412837 4414213 D sensor protein ZraS 4412837..4414213 Escherichia coli 536 4188688 YP_672069.1 CDS ECP_4217 NC_008253.1 4414210 4415535 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4414210..4415535 Escherichia coli 536 4188689 YP_672070.1 CDS ECP_4218 NC_008253.1 4415532 4416821 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4415532..4416821) Escherichia coli 536 4188690 YP_672071.1 CDS purH NC_008253.1 4416833 4418422 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4416833..4418422) Escherichia coli 536 4188691 YP_672072.1 CDS ECP_4221 NC_008253.1 4424126 4424509 D hypothetical protein 4424126..4424509 Escherichia coli 536 4188693 YP_672073.1 CDS ECP_4222 NC_008253.1 4424573 4425016 R hypothetical protein complement(4424573..4425016) Escherichia coli 536 4188694 YP_672074.1 CDS ECP_4223 NC_008253.1 4425173 4426102 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4425173..4426102 Escherichia coli 536 4188695 YP_672075.1 CDS ECP_4224 NC_008253.1 4426371 4427972 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4426371..4427972 Escherichia coli 536 4188696 YP_672076.1 CDS ECP_4225 NC_008253.1 4428002 4429306 D isocitrate lyase 4428002..4429306 Escherichia coli 536 4188923 YP_672077.1 CDS aceK NC_008253.1 4429522 4431246 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4429522..4431246 Escherichia coli 536 4188924 YP_672078.1 CDS ECP_4227 NC_008253.1 4431263 4432087 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4431263..4432087) Escherichia coli 536 4188925 YP_672079.1 CDS metH NC_008253.1 4432272 4435970 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4432272..4435970 Escherichia coli 536 4188926 YP_672080.1 CDS ECP_4229 NC_008253.1 4436030 4436350 D hypothetical protein 4436030..4436350 Escherichia coli 536 4188927 YP_672081.1 CDS ECP_4230 NC_008253.1 4436393 4436842 D hypothetical protein 4436393..4436842 Escherichia coli 536 4188928 YP_672082.1 CDS ECP_4231 NC_008253.1 4437013 4438644 D hypothetical protein 4437013..4438644 Escherichia coli 536 4188929 YP_672083.1 CDS ECP_4232 NC_008253.1 4438734 4439423 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4438734..4439423) Escherichia coli 536 4188930 YP_672084.1 CDS ECP_4233 NC_008253.1 4439805 4441034 R L-sorbose 1-phosphate reductase complement(4439805..4441034) Escherichia coli 536 4188931 YP_672085.1 CDS ECP_4234 NC_008253.1 4441086 4441910 R PTS system, sorbose-specific IID component complement(4441086..4441910) Escherichia coli 536 4188932 YP_672086.1 CDS ECP_4235 NC_008253.1 4441921 4442718 R PTS system sorbose-specific transporter subunit IIC complement(4441921..4442718) Escherichia coli 536 4188933 YP_672087.1 CDS ECP_4236 NC_008253.1 4442784 4443278 R PTS system, sorbose-specific IIB component complement(4442784..4443278) Escherichia coli 536 4188934 YP_672088.1 CDS ECP_4237 NC_008253.1 4443278 4443685 R PTS system, sorbose-specific IIA component complement(4443278..4443685) Escherichia coli 536 4188935 YP_672089.1 CDS ECP_4238 NC_008253.1 4443695 4444501 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4443695..4444501) Escherichia coli 536 4188936 YP_672090.1 CDS ECP_4239 NC_008253.1 4444571 4445518 R transcriptional regulator of sorbose uptake and utilization genes complement(4444571..4445518) Escherichia coli 536 4188937 YP_672091.1 CDS ECP_4240 NC_008253.1 4445866 4446738 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4445866..4446738 Escherichia coli 536 4188938 YP_672092.1 CDS ECP_4241 NC_008253.1 4446739 4447011 R hypothetical protein complement(4446739..4447011) Escherichia coli 536 4188939 YP_672093.1 CDS ECP_4242 NC_008253.1 4447264 4448613 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase complement(4447264..4448613) Escherichia coli 536 4188940 YP_672094.1 CDS pgi NC_008253.1 4449138 4450787 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4449138..4450787 Escherichia coli 536 4188941 YP_672095.1 CDS ECP_4244 NC_008253.1 4451286 4451528 D hypothetical protein 4451286..4451528 Escherichia coli 536 4188942 YP_672096.1 CDS ECP_4245 NC_008253.1 4451715 4452353 D lipoprotein YjbF 4451715..4452353 Escherichia coli 536 4187946 YP_672097.1 CDS ECP_4246 NC_008253.1 4452350 4453087 D hypothetical protein 4452350..4453087 Escherichia coli 536 4187947 YP_672098.1 CDS ECP_4247 NC_008253.1 4453087 4455183 D lipoprotein YjbH 4453087..4455183 Escherichia coli 536 4187948 YP_672099.1 CDS ECP_4248 NC_008253.1 4455568 4455726 D hypothetical protein 4455568..4455726 Escherichia coli 536 4187949 YP_672100.1 CDS ECP_4249 NC_008253.1 4455723 4456133 D phosphate-starvation-inducible protein PsiE 4455723..4456133 Escherichia coli 536 4187950 YP_672101.1 CDS malG NC_008253.1 4456227 4457117 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4456227..4457117) Escherichia coli 536 4187951 YP_672102.1 CDS malF NC_008253.1 4457132 4458676 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4457132..4458676) Escherichia coli 536 4187952 YP_672103.1 CDS malE NC_008253.1 4458830 4460020 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4458830..4460020) Escherichia coli 536 4187953 YP_672104.1 CDS ECP_4253 NC_008253.1 4460385 4461500 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4460385..4461500 Escherichia coli 536 4187954 YP_672105.1 CDS lamB NC_008253.1 4461572 4462912 D porin involved in the transport of maltose and maltodextrins; maltoporin 4461572..4462912 Escherichia coli 536 4187955 YP_672106.1 CDS ECP_4255 NC_008253.1 4463235 4464155 D maltose regulon periplasmic protein 4463235..4464155 Escherichia coli 536 4187956 YP_672107.1 CDS ubiC NC_008253.1 4464334 4464831 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4464334..4464831 Escherichia coli 536 4187957 YP_672108.1 CDS ubiA NC_008253.1 4464844 4465716 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4464844..4465716 Escherichia coli 536 4187958 YP_672109.1 CDS ECP_4260 NC_008253.1 4468464 4468832 D diacylglycerol kinase 4468464..4468832 Escherichia coli 536 4187961 YP_672110.1 CDS ECP_4261 NC_008253.1 4468942 4469550 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4468942..4469550 Escherichia coli 536 4187962 YP_672111.1 CDS ECP_4262 NC_008253.1 4469569 4470948 D DNA-damage-inducible SOS response protein 4469569..4470948 Escherichia coli 536 4189333 YP_672112.1 CDS ECP_4263 NC_008253.1 4471064 4471273 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4471064..4471273 Escherichia coli 536 4189334 YP_672113.1 CDS ECP_4264 NC_008253.1 4471315 4471908 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4471315..4471908) Escherichia coli 536 4189335 YP_672114.1 CDS ECP_4265 NC_008253.1 4471986 4472981 D tRNA-dihydrouridine synthase A 4471986..4472981 Escherichia coli 536 4189336 YP_672115.1 CDS pspG NC_008253.1 4472938 4473357 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4472938..4473357 Escherichia coli 536 4189337 YP_672116.1 CDS ECP_4267 NC_008253.1 4473522 4474505 R quinone oxidoreductase complement(4473522..4474505) Escherichia coli 536 4189338 YP_672117.1 CDS ECP_4268 NC_008253.1 4474588 4476003 D unwinds double stranded DNA; replicative DNA helicase 4474588..4476003 Escherichia coli 536 4189339 YP_672118.1 CDS ECP_4269 NC_008253.1 4476038 4476658 R hypothetical protein complement(4476038..4476658) Escherichia coli 536 4189340 YP_672119.1 CDS alr NC_008253.1 4476725 4477804 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4476725..4477804 Escherichia coli 536 4189341 YP_672120.1 CDS ECP_4271 NC_008253.1 4477827 4478384 D hypothetical protein 4477827..4478384 Escherichia coli 536 4189342 YP_672121.1 CDS ECP_4272 NC_008253.1 4478381 4479385 D hypothetical protein 4478381..4479385 Escherichia coli 536 4189343 YP_672122.1 CDS ECP_4273 NC_008253.1 4479467 4480660 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4479467..4480660 Escherichia coli 536 4189344 YP_672123.1 CDS sucA NC_008253.1 4480842 4483586 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4480842..4483586 Escherichia coli 536 4189345 YP_672124.1 CDS ECP_4275 NC_008253.1 4483619 4484773 D component of 2-oxoglutarate dehydrogenase complex; dihydrolipoamide succinyltransferase 4483619..4484773 Escherichia coli 536 4189346 YP_672125.1 CDS ECP_4276 NC_008253.1 4484785 4486203 D pyridine nucleotide-disulfide oxidoreductase 4484785..4486203 Escherichia coli 536 4189347 YP_672126.1 CDS ECP_4277 NC_008253.1 4486225 4487394 D succinyl-CoA synthetase beta chain 4486225..4487394 Escherichia coli 536 4189348 YP_672127.1 CDS ECP_4278 NC_008253.1 4487407 4488279 D succinyl-CoA synthetase subunit alpha 4487407..4488279 Escherichia coli 536 4189349 YP_672128.1 CDS ECP_4279 NC_008253.1 4488491 4489990 D sodium:sulfate symporter transmembrane protein 4488491..4489990 Escherichia coli 536 4189350 YP_672129.1 CDS ECP_4280 NC_008253.1 4490002 4491075 D malate/L-lactate dehydrogenase YbiC 4490002..4491075 Escherichia coli 536 4189351 YP_672130.1 CDS ECP_4281 NC_008253.1 4491064 4492422 R two component response regulator complement(4491064..4492422) Escherichia coli 536 4187831 YP_672131.1 CDS ECP_4282 NC_008253.1 4492415 4494235 R transport sensor protein complement(4492415..4494235) Escherichia coli 536 4187832 YP_672132.1 CDS aphA NC_008253.1 4494512 4495225 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4494512..4495225 Escherichia coli 536 4187833 YP_672133.1 CDS ECP_4284 NC_008253.1 4495336 4495752 D hypothetical protein 4495336..4495752 Escherichia coli 536 4187834 YP_672134.1 CDS ECP_4285 NC_008253.1 4495756 4496112 D hypothetical protein 4495756..4496112 Escherichia coli 536 4187835 YP_672135.1 CDS uvrA NC_008253.1 4496147 4498969 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4496147..4498969) Escherichia coli 536 4187836 YP_672136.1 CDS ECP_4287 NC_008253.1 4499224 4499760 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4499224..4499760 Escherichia coli 536 4187837 YP_672137.1 CDS ECP_4288 NC_008253.1 4499859 4500140 R hypothetical protein complement(4499859..4500140) Escherichia coli 536 4187838 YP_672138.1 CDS ECP_4289 NC_008253.1 4500569 4502155 D hypothetical protein 4500569..4502155 Escherichia coli 536 4187839 YP_672139.1 CDS ECP_4290 NC_008253.1 4502158 4502481 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4502158..4502481) Escherichia coli 536 4187840 YP_672140.1 CDS ECP_4291 NC_008253.1 4502567 4503031 D redox-sensitive transcriptional activator SoxR 4502567..4503031 Escherichia coli 536 4187841 YP_672141.1 CDS ECP_4292 NC_008253.1 4503322 4503537 R hypothetical protein complement(4503322..4503537) Escherichia coli 536 4187842 YP_672142.1 CDS ECP_4293 NC_008253.1 4503578 4504927 D xanthine/uracil permeases family protein YjcD 4503578..4504927 Escherichia coli 536 4187843 YP_672143.1 CDS ECP_4294 NC_008253.1 4505078 4506727 D sodium/hydrogen exchanger family protein YjcE 4505078..4506727 Escherichia coli 536 4187844 YP_672144.1 CDS ECP_4295 NC_008253.1 4506763 4507095 R hypothetical protein complement(4506763..4507095) Escherichia coli 536 4187845 YP_672145.1 CDS ECP_4296 NC_008253.1 4507166 4507558 R hypothetical protein complement(4507166..4507558) Escherichia coli 536 4187846 YP_672146.1 CDS ECP_4297 NC_008253.1 4507662 4508072 D murein hydrolase exporter 4507662..4508072 Escherichia coli 536 4187847 YP_672147.1 CDS ECP_4298 NC_008253.1 4508065 4508754 D LrgB family murein hydrolase regulator 4508065..4508754 Escherichia coli 536 4187848 YP_672148.1 CDS actP NC_008253.1 4508793 4510442 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4508793..4510442) Escherichia coli 536 4187849 YP_672149.1 CDS ECP_4300 NC_008253.1 4510439 4510753 R hypothetical protein complement(4510439..4510753) Escherichia coli 536 4187850 YP_672150.1 CDS ECP_4301 NC_008253.1 4511056 4513014 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4511056..4513014) Escherichia coli 536 4187304 YP_672151.1 CDS ECP_4302 NC_008253.1 4513288 4513485 D hypothetical protein 4513288..4513485 Escherichia coli 536 4187305 YP_672152.1 CDS nrfA NC_008253.1 4513406 4514842 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4513406..4514842 Escherichia coli 536 4187306 YP_672153.1 CDS ECP_4304 NC_008253.1 4514887 4515453 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4514887..4515453 Escherichia coli 536 4187307 YP_672154.1 CDS ECP_4305 NC_008253.1 4515450 4516121 D NrfC protein 4515450..4516121 Escherichia coli 536 4187308 YP_672155.1 CDS ECP_4306 NC_008253.1 4516118 4517074 D NrfD protein 4516118..4517074 Escherichia coli 536 4187309 YP_672156.1 CDS ECP_4307 NC_008253.1 4517154 4518812 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4517154..4518812 Escherichia coli 536 4187310 YP_672157.1 CDS ECP_4308 NC_008253.1 4518805 4519188 D formate-dependent nitrite reductase complex subunit NrfF 4518805..4519188 Escherichia coli 536 4187311 YP_672158.1 CDS ECP_4309 NC_008253.1 4519185 4519781 D formate-dependent nitrite reductase complex subunit NrfG 4519185..4519781 Escherichia coli 536 4187312 YP_672159.1 CDS gltP NC_008253.1 4520124 4521437 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4520124..4521437 Escherichia coli 536 4187313 YP_672160.1 CDS ECP_4311 NC_008253.1 4522153 4522674 D IS transposase 4522153..4522674 Escherichia coli 536 4187314 YP_672161.1 CDS ECP_4312 NC_008253.1 4522779 4523501 D transposase 4522779..4523501 Escherichia coli 536 4187315 YP_672162.1 CDS ECP_4313 NC_008253.1 4523699 4524388 R hypothetical protein complement(4523699..4524388) Escherichia coli 536 4187316 YP_672163.1 CDS ECP_4314 NC_008253.1 4524499 4525203 R ABC transporter ATP-binding protein complement(4524499..4525203) Escherichia coli 536 4187317 YP_672164.1 CDS ECP_4315 NC_008253.1 4525190 4526044 R ABC transporter transporter ATP-binding protein complement(4525190..4526044) Escherichia coli 536 4187318 YP_672165.1 CDS ECP_4316 NC_008253.1 4526019 4526852 R transporter permease complement(4526019..4526852) Escherichia coli 536 4187319 YP_672166.1 CDS ECP_4317 NC_008253.1 4526852 4527994 R transporter permease complement(4526852..4527994) Escherichia coli 536 4187320 YP_672167.1 CDS ECP_4318 NC_008253.1 4528001 4529569 R dipeptide binding periplasmic protein complement(4528001..4529569) Escherichia coli 536 4187321 YP_672168.1 CDS ECP_4321 NC_008253.1 4532289 4533755 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(4532289..4533755) Escherichia coli 536 4190354 YP_672169.1 CDS ECP_4322 NC_008253.1 4533752 4535803 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4533752..4535803) Escherichia coli 536 4190355 YP_672170.1 CDS ECP_4323 NC_008253.1 4535803 4536834 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4535803..4536834) Escherichia coli 536 4190356 YP_672171.1 CDS ECP_4324 NC_008253.1 4536853 4537128 R hypothetical protein complement(4536853..4537128) Escherichia coli 536 4190357 YP_672172.1 CDS ECP_4325 NC_008253.1 4537337 4539322 R hypothetical protein complement(4537337..4539322) Escherichia coli 536 4190358 YP_672173.1 CDS ECP_4326 NC_008253.1 4539595 4540524 R D-allose kinase complement(4539595..4540524) Escherichia coli 536 4190359 YP_672174.1 CDS ECP_4327 NC_008253.1 4540508 4541203 R allulose-6-phosphate 3-epimerase complement(4540508..4541203) Escherichia coli 536 4190360 YP_672175.1 CDS ECP_4330 NC_008253.1 4542172 4543704 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4542172..4543704) Escherichia coli 536 4190363 YP_672176.1 CDS ECP_4331 NC_008253.1 4543832 4544773 R D-allose transporter subunit complement(4543832..4544773) Escherichia coli 536 4190364 YP_672177.1 CDS ECP_4332 NC_008253.1 4544826 4545716 R involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR complement(4544826..4545716) Escherichia coli 536 4190365 YP_672178.1 CDS ECP_4333 NC_008253.1 4546075 4546524 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4546075..4546524 Escherichia coli 536 4190366 YP_672179.1 CDS ECP_4334 NC_008253.1 4546593 4546922 D hypothetical protein 4546593..4546922 Escherichia coli 536 4190367 YP_672180.1 CDS phnP NC_008253.1 4546950 4547708 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4546950..4547708) Escherichia coli 536 4187226 YP_672181.1 CDS ECP_4336 NC_008253.1 4547710 4548144 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4547710..4548144) Escherichia coli 536 4187227 YP_672182.1 CDS ECP_4337 NC_008253.1 4548131 4548688 R ribose 1,5-bisphosphokinase complement(4548131..4548688) Escherichia coli 536 4187228 YP_672183.1 CDS ECP_4338 NC_008253.1 4548688 4549824 R HisM-like integral membrane protein PhnM complement(4548688..4549824) Escherichia coli 536 4187229 YP_672184.1 CDS ECP_4339 NC_008253.1 4549821 4550501 R phosphonates transport ATP-binding protein PhnL complement(4549821..4550501) Escherichia coli 536 4187230 YP_672185.1 CDS phnK NC_008253.1 4550612 4551370 R phosphonate C-P lyase system protein PhnK complement(4550612..4551370) Escherichia coli 536 4187231 YP_672186.1 CDS ECP_4341 NC_008253.1 4551367 4552212 R PhnJ protein complement(4551367..4552212) Escherichia coli 536 4187232 YP_672187.1 CDS ECP_4342 NC_008253.1 4552205 4553269 R PhnI protein complement(4552205..4553269) Escherichia coli 536 4187233 YP_672188.1 CDS phnH NC_008253.1 4553269 4553853 R carbon-phosphorus lyase complex subunit complement(4553269..4553853) Escherichia coli 536 4187234 YP_672189.1 CDS ECP_4344 NC_008253.1 4553850 4554302 R PhnG protein complement(4553850..4554302) Escherichia coli 536 4187235 YP_672190.1 CDS ECP_4345 NC_008253.1 4554303 4555028 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4554303..4555028) Escherichia coli 536 4187236 YP_672191.1 CDS ECP_4346 NC_008253.1 4555049 4555828 R phosphonates transport system permease PhnE complement(4555049..4555828) Escherichia coli 536 4187237 YP_672192.1 CDS ECP_4347 NC_008253.1 4555934 4556950 R PhnD protein complement(4555934..4556950) Escherichia coli 536 4187238 YP_672193.1 CDS ECP_4348 NC_008253.1 4556975 4557763 R phosphonate/organophosphate ester transporter subunit complement(4556975..4557763) Escherichia coli 536 4187239 YP_672194.1 CDS ECP_4349 NC_008253.1 4557896 4558339 R hypothetical protein complement(4557896..4558339) Escherichia coli 536 4187240 YP_672195.1 CDS ECP_4350 NC_008253.1 4558499 4558834 R hypothetical protein complement(4558499..4558834) Escherichia coli 536 4187241 YP_672196.1 CDS ECP_4351 NC_008253.1 4558806 4559018 D hypothetical protein 4558806..4559018 Escherichia coli 536 4187242 YP_672197.1 CDS ECP_4352 NC_008253.1 4559237 4561465 D hypothetical protein 4559237..4561465 Escherichia coli 536 4187243 YP_672198.1 CDS ECP_4353 NC_008253.1 4561462 4562340 D hypothetical protein 4561462..4562340 Escherichia coli 536 4187244 YP_672199.1 CDS ECP_4354 NC_008253.1 4562604 4564106 D proline/glycine betaine transporter 4562604..4564106 Escherichia coli 536 4191628 YP_672200.1 CDS ECP_4355 NC_008253.1 4564283 4565374 R sensor protein BasS/PmrB complement(4564283..4565374) Escherichia coli 536 4191629 YP_672201.1 CDS ECP_4356 NC_008253.1 4565384 4566052 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4565384..4566052) Escherichia coli 536 4191630 YP_672202.1 CDS ECP_4357 NC_008253.1 4566049 4567722 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4566049..4567722) Escherichia coli 536 4191631 YP_672203.1 CDS ECP_4358 NC_008253.1 4567796 4569133 R arginine:agmatin antiporter complement(4567796..4569133) Escherichia coli 536 4191632 YP_672204.1 CDS ECP_4359 NC_008253.1 4569270 4570031 R regulatory protein AdiY complement(4569270..4570031) Escherichia coli 536 4191633 YP_672205.1 CDS ECP_4360 NC_008253.1 4570367 4572637 R biodegradative arginine decarboxylase complement(4570367..4572637) Escherichia coli 536 4191634 YP_672206.1 CDS ECP_4361 NC_008253.1 4572833 4573741 R DNA-binding transcriptional regulator MelR complement(4572833..4573741) Escherichia coli 536 4191635 YP_672207.1 CDS ECP_4362 NC_008253.1 4574024 4575379 D alpha-galactosidase 4574024..4575379 Escherichia coli 536 4191636 YP_672208.1 CDS ECP_4363 NC_008253.1 4575376 4576026 R hypothetical protein complement(4575376..4576026) Escherichia coli 536 4191637 YP_672209.1 CDS ECP_4364 NC_008253.1 4576149 4577795 R fumarate hydratase class I, anaerobic complement(4576149..4577795) Escherichia coli 536 4191638 YP_672210.1 CDS ECP_4365 NC_008253.1 4577873 4579213 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4577873..4579213) Escherichia coli 536 4191639 YP_672211.1 CDS ECP_4366 NC_008253.1 4579281 4579439 D hypothetical protein 4579281..4579439 Escherichia coli 536 4191640 YP_672212.1 CDS ECP_4367 NC_008253.1 4579784 4580503 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4579784..4580503) Escherichia coli 536 4191641 YP_672213.1 CDS ECP_4368 NC_008253.1 4580500 4582131 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4580500..4582131) Escherichia coli 536 4191642 YP_672214.1 CDS ECP_4369 NC_008253.1 4582312 4582542 D hypothetical protein 4582312..4582542 Escherichia coli 536 4191643 YP_672215.1 CDS ECP_4370 NC_008253.1 4582554 4582826 D hypothetical protein 4582554..4582826 Escherichia coli 536 4191644 YP_672216.1 CDS ECP_4371 NC_008253.1 4583055 4583351 D hypothetical protein 4583055..4583351 Escherichia coli 536 4191645 YP_672217.1 CDS ECP_4372 NC_008253.1 4583379 4583552 D hypothetical protein 4583379..4583552 Escherichia coli 536 4191646 YP_672218.1 CDS ECP_4373 NC_008253.1 4583671 4585188 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4583671..4585188) Escherichia coli 536 4191647 YP_672219.1 CDS ECP_4374 NC_008253.1 4585425 4586882 R POT family di-/tripeptide transport protein complement(4585425..4586882) Escherichia coli 536 4190443 YP_672220.1 CDS ECP_4375 NC_008253.1 4586941 4589088 R lysine decarboxylase, inducible complement(4586941..4589088) Escherichia coli 536 4190444 YP_672221.1 CDS cadB NC_008253.1 4589168 4590502 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4589168..4590502) Escherichia coli 536 4190445 YP_672222.1 CDS ECP_4377 NC_008253.1 4590868 4592406 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4590868..4592406) Escherichia coli 536 4190446 YP_672223.1 CDS ECP_4378 NC_008253.1 4592693 4592911 D hypothetical protein 4592693..4592911 Escherichia coli 536 4190447 YP_672224.1 CDS ECP_4379 NC_008253.1 4593205 4593780 R transcriptional regulator complement(4593205..4593780) Escherichia coli 536 4190448 YP_672225.1 CDS dipZ NC_008253.1 4593817 4595514 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4593817..4595514) Escherichia coli 536 4190449 YP_672226.1 CDS ECP_4381 NC_008253.1 4595490 4595828 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4595490..4595828) Escherichia coli 536 4190450 YP_672227.1 CDS ECP_4382 NC_008253.1 4595944 4597245 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4595944..4597245) Escherichia coli 536 4190451 YP_672228.1 CDS aspA NC_008253.1 4597363 4598799 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4597363..4598799) Escherichia coli 536 4190452 YP_672229.1 CDS fxsA NC_008253.1 4599136 4599612 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4599136..4599612 Escherichia coli 536 4190453 YP_672230.1 CDS ECP_4385 NC_008253.1 4599628 4600884 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(4599628..4600884) Escherichia coli 536 4190454 YP_672231.1 CDS groES NC_008253.1 4601160 4601453 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4601160..4601453 Escherichia coli 536 4190455 YP_672232.1 CDS groEL NC_008253.1 4601497 4603143 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4601497..4603143 Escherichia coli 536 4190456 YP_672233.1 CDS ECP_4388 NC_008253.1 4603281 4603634 D hypothetical protein 4603281..4603634 Escherichia coli 536 4190457 YP_672234.1 CDS ECP_4389 NC_008253.1 4603684 4604553 R hypothetical protein complement(4603684..4604553) Escherichia coli 536 4190458 YP_672235.1 CDS ECP_4390 NC_008253.1 4604788 4605816 R hypothetical protein complement(4604788..4605816) Escherichia coli 536 4190459 YP_672236.1 CDS ECP_4391 NC_008253.1 4605858 4606424 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4605858..4606424 Escherichia coli 536 4190460 YP_672237.1 CDS ECP_4392 NC_008253.1 4606476 4606601 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4606476..4606601 Escherichia coli 536 4190461 YP_672238.1 CDS ECP_4393 NC_008253.1 4606712 4606858 D entericidin B 4606712..4606858 Escherichia coli 536 4190197 YP_672239.1 CDS ECP_4394 NC_008253.1 4607048 4607365 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4607048..4607365 Escherichia coli 536 4190198 YP_672240.1 CDS ECP_4395 NC_008253.1 4607362 4607895 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4607362..4607895) Escherichia coli 536 4190199 YP_672241.1 CDS ampC NC_008253.1 4607984 4609246 R beta-lactamase complement(4607984..4609246) Escherichia coli 536 4190200 YP_672242.1 CDS ECP_4397 NC_008253.1 4609180 4609539 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4609180..4609539) Escherichia coli 536 4190201 YP_672243.1 CDS ECP_4398 NC_008253.1 4609550 4609945 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4609550..4609945) Escherichia coli 536 4190202 YP_672244.1 CDS ECP_4399 NC_008253.1 4609956 4610690 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4609956..4610690) Escherichia coli 536 4190203 YP_672245.1 CDS ECP_4400 NC_008253.1 4610683 4612491 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4610683..4612491) Escherichia coli 536 4190204 YP_672246.1 CDS ECP_4401 NC_008253.1 4612816 4613793 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4612816..4613793 Escherichia coli 536 4190205 YP_672247.1 CDS ECP_4402 NC_008253.1 4614012 4615514 D transporter YjeM 4614012..4615514 Escherichia coli 536 4190206 YP_672248.1 CDS ECP_4403 NC_008253.1 4615665 4618988 R hypothetical protein complement(4615665..4618988) Escherichia coli 536 4190207 YP_672249.1 CDS psd NC_008253.1 4619010 4619978 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4619010..4619978) Escherichia coli 536 4190208 YP_672250.1 CDS ECP_4405 NC_008253.1 4620075 4621160 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4620075..4621160) Escherichia coli 536 4190209 YP_672251.2 CDS ECP_4406 NC_008253.1 4621222 4621767 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4621222..4621767 Escherichia coli 536 4190210 YP_672252.1 CDS ECP_4407 NC_008253.1 4621802 4621933 D hypothetical protein 4621802..4621933 Escherichia coli 536 4190211 YP_672253.1 CDS ECP_4411 NC_008253.1 4622545 4623684 R electron transport protein YjeS complement(4622545..4623684) Escherichia coli 536 4191424 YP_672254.1 CDS ECP_4412 NC_008253.1 4623683 4625230 D hypothetical protein 4623683..4625230 Escherichia coli 536 4191425 YP_672255.1 CDS ECP_4413 NC_008253.1 4625202 4625663 D possibly involved in cell wall synthesis; ATPase 4625202..4625663 Escherichia coli 536 4191426 YP_672256.1 CDS ECP_4414 NC_008253.1 4625682 4627019 D N-acetylmuramoyl-L-alanine amidase 4625682..4627019 Escherichia coli 536 4191427 YP_672257.1 CDS mutL NC_008253.1 4627029 4628876 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4627029..4628876 Escherichia coli 536 4191428 YP_672258.1 CDS miaA NC_008253.1 4628869 4629819 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4628869..4629819 Escherichia coli 536 4191429 YP_672259.1 CDS hfq NC_008253.1 4629905 4630213 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4629905..4630213 Escherichia coli 536 4191430 YP_672260.1 CDS ECP_4418 NC_008253.1 4630289 4631569 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4630289..4631569 Escherichia coli 536 4191431 YP_672261.1 CDS ECP_4419 NC_008253.1 4631655 4632914 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4631655..4632914 Escherichia coli 536 4191432 YP_672262.1 CDS ECP_4420 NC_008253.1 4632917 4633921 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4632917..4633921 Escherichia coli 536 4191433 YP_672263.1 CDS ECP_4421 NC_008253.1 4634003 4634200 D membrane protein YjeT 4634003..4634200 Escherichia coli 536 4191434 YP_672264.1 CDS ECP_4422 NC_008253.1 4634304 4635602 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4634304..4635602 Escherichia coli 536 4191435 YP_672265.1 CDS ECP_4423 NC_008253.1 4635807 4636232 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4635807..4636232 Escherichia coli 536 4191436 YP_672266.1 CDS ECP_4424 NC_008253.1 4636271 4638712 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4636271..4638712 Escherichia coli 536 4191437 YP_672267.1 CDS ECP_4425 NC_008253.1 4638803 4639534 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4638803..4639534 Escherichia coli 536 4191438 YP_672268.1 CDS ECP_4426 NC_008253.1 4639661 4640062 D hypothetical protein 4639661..4640062 Escherichia coli 536 4191439 YP_672269.1 CDS ECP_4427 NC_008253.1 4640081 4640779 D phage shock protein A 4640081..4640779 Escherichia coli 536 4191440 YP_672270.1 CDS ECP_4428 NC_008253.1 4640829 4641488 D hypothetical protein 4640829..4641488 Escherichia coli 536 4191441 YP_672271.1 CDS ECP_4429 NC_008253.1 4641506 4641904 D membrane protein YjfL 4641506..4641904 Escherichia coli 536 4190021 YP_672272.1 CDS ECP_4430 NC_008253.1 4641914 4642552 D hypothetical protein 4641914..4642552 Escherichia coli 536 4190022 YP_672273.1 CDS ECP_4431 NC_008253.1 4642555 4643718 D glutathionylspermidine synthase YjfC 4642555..4643718 Escherichia coli 536 4190023 YP_672274.1 CDS ECP_4432 NC_008253.1 4643787 4645427 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4643787..4645427 Escherichia coli 536 4190024 YP_672275.1 CDS ECP_4433 NC_008253.1 4645544 4645831 R hypothetical protein complement(4645544..4645831) Escherichia coli 536 4190025 YP_672276.1 CDS ECP_4434 NC_008253.1 4645968 4646396 R hypothetical protein complement(4645968..4646396) Escherichia coli 536 4190026 YP_672277.1 CDS ECP_4435 NC_008253.1 4646479 4647228 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4646479..4647228 Escherichia coli 536 4190027 YP_672278.1 CDS ECP_4436 NC_008253.1 4647225 4647980 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4647225..4647980) Escherichia coli 536 4190028 YP_672279.1 CDS ECP_4437 NC_008253.1 4648088 4649152 R L-ascorbate 6-phosphate lactonase complement(4648088..4649152) Escherichia coli 536 4190029 YP_672280.1 CDS ulaA NC_008253.1 4649507 4650904 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4649507..4650904 Escherichia coli 536 4190030 YP_672281.1 CDS ECP_4439 NC_008253.1 4650920 4651225 D L-ascorbate-specific enzyme IIB component of PTS 4650920..4651225 Escherichia coli 536 4190031 YP_672282.1 CDS ECP_4440 NC_008253.1 4651235 4651699 D L-ascorbate-specific enzyme IIA component of PTS 4651235..4651699 Escherichia coli 536 4190032 YP_672283.1 CDS ulaD NC_008253.1 4651713 4652363 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4651713..4652363 Escherichia coli 536 4190033 YP_672284.1 CDS ECP_4442 NC_008253.1 4652373 4653227 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4652373..4653227 Escherichia coli 536 4190034 YP_672285.1 CDS sgaE NC_008253.1 4653227 4653913 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4653227..4653913 Escherichia coli 536 4190035 YP_672286.1 CDS ECP_4444 NC_008253.1 4654043 4654318 R hypothetical protein complement(4654043..4654318) Escherichia coli 536 4190036 YP_672287.1 CDS ECP_4445 NC_008253.1 4654737 4655042 D 30S ribosomal protein S6 4654737..4655042 Escherichia coli 536 4190037 YP_672288.1 CDS ECP_4446 NC_008253.1 4655049 4655363 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4655049..4655363 Escherichia coli 536 4190038 YP_672289.1 CDS rpsR NC_008253.1 4655368 4655595 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4655368..4655595 Escherichia coli 536 4190039 YP_672290.1 CDS rplI NC_008253.1 4655637 4656086 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4655637..4656086 Escherichia coli 536 4190040 YP_672291.1 CDS ECP_4449 NC_008253.1 4656197 4656394 R hypothetical protein complement(4656197..4656394) Escherichia coli 536 4187851 YP_672292.1 CDS ECP_4450 NC_008253.1 4656488 4656979 D hypothetical protein 4656488..4656979 Escherichia coli 536 4187852 YP_672293.1 CDS ECP_4451 NC_008253.1 4656982 4657569 D hypothetical protein 4656982..4657569 Escherichia coli 536 4187853 YP_672294.1 CDS ECP_4452 NC_008253.1 4657640 4658251 D hypothetical protein 4657640..4658251 Escherichia coli 536 4187854 YP_672295.1 CDS ECP_4453 NC_008253.1 4658394 4659671 R permease complement(4658394..4659671) Escherichia coli 536 4187855 YP_672296.1 CDS ECP_4454 NC_008253.1 4659764 4661836 R oxidoreductase complement(4659764..4661836) Escherichia coli 536 4187856 YP_672297.1 CDS ECP_4455 NC_008253.1 4661833 4663374 R acetyl-CoA:acetoacetyl-CoA transferase subunit beta complement(4661833..4663374) Escherichia coli 536 4187857 YP_672298.1 CDS ECP_4456 NC_008253.1 4663384 4664160 R 3-hydroxybutyryl-CoA dehydratase complement(4663384..4664160) Escherichia coli 536 4187858 YP_672299.1 CDS ECP_4457 NC_008253.1 4664170 4665012 R endonuclease complement(4664170..4665012) Escherichia coli 536 4187859 YP_672300.1 CDS ECP_4458 NC_008253.1 4665022 4665813 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(4665022..4665813) Escherichia coli 536 4187860 YP_672301.1 CDS ECP_4459 NC_008253.1 4666026 4666673 D TetR/AcrR family transcriptional regulator 4666026..4666673 Escherichia coli 536 4187861 YP_672302.1 CDS ECP_4460 NC_008253.1 4666657 4667295 R membrane protein YtfB complement(4666657..4667295) Escherichia coli 536 4187862 YP_672303.1 CDS ECP_4461 NC_008253.1 4667513 4668133 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4667513..4668133 Escherichia coli 536 4187863 YP_672304.1 CDS ECP_4462 NC_008253.1 4668442 4669854 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4668442..4669854 Escherichia coli 536 4187864 YP_672305.1 CDS ECP_4463 NC_008253.1 4669899 4670561 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4669899..4670561) Escherichia coli 536 4187865 YP_672306.1 CDS ECP_4464 NC_008253.1 4670669 4671643 R membrane protein YtfF complement(4670669..4671643) Escherichia coli 536 4187866 YP_672307.1 CDS ECP_4465 NC_008253.1 4671743 4672603 R hypothetical protein complement(4671743..4672603) Escherichia coli 536 4187867 YP_672308.1 CDS ECP_4466 NC_008253.1 4672692 4673072 D transcriptional regulator YtfH 4672692..4673072 Escherichia coli 536 4187868 YP_672309.1 CDS cpdB NC_008253.1 4673201 4675144 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4673201..4675144) Escherichia coli 536 4187869 YP_672310.1 CDS ECP_4468 NC_008253.1 4675334 4676074 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4675334..4676074 Escherichia coli 536 4187887 YP_672311.1 CDS ECP_4469 NC_008253.1 4676064 4676621 R protein YtfJ complement(4676064..4676621) Escherichia coli 536 4187888 YP_672312.1 CDS ECP_4470 NC_008253.1 4676946 4677152 D hypothetical protein 4676946..4677152 Escherichia coli 536 4187889 YP_672313.1 CDS ECP_4471 NC_008253.1 4677230 4678573 R hypothetical protein complement(4677230..4678573) Escherichia coli 536 4187890 YP_672314.1 CDS ECP_4472 NC_008253.1 4678896 4679534 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4678896..4679534) Escherichia coli 536 4187891 YP_672315.1 CDS ECP_4473 NC_008253.1 4679741 4681474 D outer membrane protein 4679741..4681474 Escherichia coli 536 4187892 YP_672316.1 CDS ECP_4474 NC_008253.1 4681471 4685250 D hypothetical protein 4681471..4685250 Escherichia coli 536 4187893 YP_672317.1 CDS ECP_4475 NC_008253.1 4685253 4685594 D hypothetical protein 4685253..4685594 Escherichia coli 536 4187894 YP_672318.1 CDS ECP_4476 NC_008253.1 4685973 4686503 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4685973..4686503) Escherichia coli 536 4187895 YP_672319.1 CDS ECP_4477 NC_008253.1 4686813 4687769 D ABC transporter substrate-binding protein YtfQ 4686813..4687769 Escherichia coli 536 4187896 YP_672320.1 CDS ECP_4478 NC_008253.1 4687909 4689411 D sugar transport system ATP-binding protein 4687909..4689411 Escherichia coli 536 4187897 YP_672321.1 CDS ECP_4479 NC_008253.1 4689425 4690447 D ABC transporter permease 4689425..4690447 Escherichia coli 536 4187898 YP_672322.1 CDS ECP_4480 NC_008253.1 4690434 4691429 D membrane component of a sugar ABC transporter system; ABC transporter permease 4690434..4691429 Escherichia coli 536 4187899 YP_672323.1 CDS ECP_4481 NC_008253.1 4691462 4692460 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4691462..4692460) Escherichia coli 536 4187900 YP_672324.1 CDS ECP_4482 NC_008253.1 4692636 4694009 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4692636..4694009 Escherichia coli 536 4187901 YP_672325.1 CDS ECP_4483 NC_008253.1 4694167 4694718 R hypothetical protein complement(4694167..4694718) Escherichia coli 536 4187902 YP_672326.1 CDS ECP_4484 NC_008253.1 4694812 4696164 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4694812..4696164 Escherichia coli 536 4187903 YP_672327.1 CDS ECP_4485 NC_008253.1 4696347 4696733 D soluble cytochrome 4696347..4696733 Escherichia coli 536 4187904 YP_672328.1 CDS nrdG NC_008253.1 4696778 4697242 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4696778..4697242) Escherichia coli 536 4187905 YP_672329.1 CDS ECP_4487 NC_008253.1 4697400 4699538 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4697400..4699538) Escherichia coli 536 4187906 YP_672330.1 CDS ECP_4488 NC_008253.1 4699932 4701587 R trehalose-6-phosphate hydrolase complement(4699932..4701587) Escherichia coli 536 4188132 YP_672331.1 CDS ECP_4489 NC_008253.1 4701637 4703058 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; trehalose(maltose)-specific PTS system components IIBC complement(4701637..4703058) Escherichia coli 536 4188133 YP_672332.1 CDS treR NC_008253.1 4703177 4704124 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4703177..4704124) Escherichia coli 536 4188134 YP_672333.1 CDS ECP_4491 NC_008253.1 4704129 4704362 D hypothetical protein 4704129..4704362 Escherichia coli 536 4188135 YP_672334.1 CDS ECP_4492 NC_008253.1 4704503 4707199 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4704503..4707199 Escherichia coli 536 4188136 YP_672335.1 CDS ECP_4493 NC_008253.1 4707405 4707791 R endoribonuclease L-PSP complement(4707405..4707791) Escherichia coli 536 4188137 YP_672336.1 CDS ECP_4494 NC_008253.1 4707864 4708325 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(4707864..4708325) Escherichia coli 536 4188138 YP_672337.1 CDS pyrB NC_008253.1 4708338 4709273 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(4708338..4709273) Escherichia coli 536 4188139 YP_672338.1 CDS ECP_4496 NC_008253.1 4709501 4709989 R arginine repressor complement(4709501..4709989) Escherichia coli 536 4188140 YP_672339.1 CDS ECP_4497 NC_008253.1 4710105 4711508 R C4-dicarboxylate anaerobic carrier complement(4710105..4711508) Escherichia coli 536 4188141 YP_672340.1 CDS ECP_4498 NC_008253.1 4711588 4712568 R ornithine carbamoyltransferase complement(4711588..4712568) Escherichia coli 536 4188142 YP_672341.1 CDS ECP_4499 NC_008253.1 4712579 4713523 R reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4712579..4713523) Escherichia coli 536 4188143 YP_672342.1 CDS ECP_4500 NC_008253.1 4713534 4714754 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(4713534..4714754) Escherichia coli 536 4188144 YP_672343.1 CDS ECP_4501 NC_008253.1 4715432 4715884 D hypothetical protein 4715432..4715884 Escherichia coli 536 4188145 YP_672344.1 CDS ECP_4504 NC_008253.1 4717096 4717512 D hypothetical protein 4717096..4717512 Escherichia coli 536 4188148 YP_672345.1 CDS ECP_4505 NC_008253.1 4717689 4718192 R acetyltransferase YjgM complement(4717689..4718192) Escherichia coli 536 4188569 YP_672346.1 CDS ECP_4506 NC_008253.1 4718385 4719572 D membrane protein YjgN 4718385..4719572 Escherichia coli 536 4188570 YP_672347.1 CDS valS NC_008253.1 4719619 4722474 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4719619..4722474) Escherichia coli 536 4188571 YP_672348.1 CDS ECP_4508 NC_008253.1 4722474 4722917 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4722474..4722917) Escherichia coli 536 4188572 YP_672349.1 CDS ECP_4509 NC_008253.1 4723175 4724686 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4723175..4724686) Escherichia coli 536 4188573 YP_672350.1 CDS ECP_4510 NC_008253.1 4724953 4726053 D membrane protein YjgP 4724953..4726053 Escherichia coli 536 4188574 YP_672351.1 CDS ECP_4511 NC_008253.1 4726053 4727135 D membrane protein YjgQ 4726053..4727135 Escherichia coli 536 4188575 YP_672352.1 CDS ECP_4512 NC_008253.1 4727296 4728798 R hypothetical protein complement(4727296..4728798) Escherichia coli 536 4188576 YP_672353.1 CDS ECP_4513 NC_008253.1 4728876 4729874 R L-idonate regulatory protein; HTH-type transcriptional regulator IdnR complement(4728876..4729874) Escherichia coli 536 4188577 YP_672354.1 CDS ECP_4514 NC_008253.1 4729941 4731260 R Gnt-II system L-idonate transporter complement(4729941..4731260) Escherichia coli 536 4188578 YP_672355.1 CDS ECP_4515 NC_008253.1 4731325 4732089 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(4731325..4732089) Escherichia coli 536 4188579 YP_672356.1 CDS ECP_4516 NC_008253.1 4732113 4733144 R NAD-binding; L-idonate 5-dehydrogenase complement(4732113..4733144) Escherichia coli 536 4188580 YP_672357.1 CDS ECP_4519 NC_008253.1 4733932 4734951 R zinc-type alcohol dehydrogenase-like protein YjgB complement(4733932..4734951) Escherichia coli 536 4188583 YP_672358.1 CDS ECP_4521 NC_008253.1 4735418 4736680 D prophage P4 integrase 4735418..4736680 Escherichia coli 536 4188621 YP_672359.1 CDS ECP_4522 NC_008253.1 4736780 4737043 R hypothetical protein complement(4736780..4737043) Escherichia coli 536 4188622 YP_672360.1 CDS ECP_4523 NC_008253.1 4737132 4740647 D superfamily I DNA helicases 4737132..4740647 Escherichia coli 536 4188623 YP_672361.1 CDS ECP_4524 NC_008253.1 4740756 4742255 R hypothetical protein complement(4740756..4742255) Escherichia coli 536 4188624 YP_672362.1 CDS ECP_4525 NC_008253.1 4742430 4743170 R OmpA family protein complement(4742430..4743170) Escherichia coli 536 4188625 YP_672363.1 CDS ECP_4526 NC_008253.1 4743388 4743756 R hypothetical protein complement(4743388..4743756) Escherichia coli 536 4188626 YP_672364.1 CDS ECP_4527 NC_008253.1 4743857 4744027 R hypothetical protein complement(4743857..4744027) Escherichia coli 536 4188627 YP_672365.1 CDS ECP_4528 NC_008253.1 4744149 4744322 R hypothetical protein complement(4744149..4744322) Escherichia coli 536 4188628 YP_672366.1 CDS ECP_4529 NC_008253.1 4744532 4744693 D hypothetical protein 4744532..4744693 Escherichia coli 536 4188629 YP_672367.1 CDS ECP_4530 NC_008253.1 4745087 4745302 R hypothetical protein complement(4745087..4745302) Escherichia coli 536 4188630 YP_672368.1 CDS ECP_4531 NC_008253.1 4745321 4745875 R PapX protein complement(4745321..4745875) Escherichia coli 536 4188631 YP_672369.1 CDS ECP_4532 NC_008253.1 4745901 4746134 R hypothetical protein complement(4745901..4746134) Escherichia coli 536 4188632 YP_672370.1 CDS ECP_4533 NC_008253.1 4746135 4747142 R protein PapG complement(4746135..4747142) Escherichia coli 536 4188633 YP_672371.1 CDS ECP_4534 NC_008253.1 4747186 4747689 R PapF protein complement(4747186..4747689) Escherichia coli 536 4188634 YP_672372.1 CDS ECP_4535 NC_008253.1 4747764 4748240 R PapE protein complement(4747764..4748240) Escherichia coli 536 4188635 YP_672373.1 CDS ECP_4536 NC_008253.1 4748312 4748848 R PapK fimbrial adapter complement(4748312..4748848) Escherichia coli 536 4188636 YP_672374.1 CDS ECP_4537 NC_008253.1 4748858 4749439 R protein PapJ complement(4748858..4749439) Escherichia coli 536 4188637 YP_672375.1 CDS ECP_4538 NC_008253.1 4749476 4750210 R chaperone protein PapD complement(4749476..4750210) Escherichia coli 536 4188638 YP_672376.1 CDS ECP_4539 NC_008253.1 4750281 4752803 R outer membrane usher protein PapC complement(4750281..4752803) Escherichia coli 536 4188639 YP_672377.1 CDS ECP_4540 NC_008253.1 4752850 4753437 R protein PapH complement(4752850..4753437) Escherichia coli 536 4188640 YP_672378.1 CDS ECP_4541 NC_008253.1 4753507 4754124 R protein PapA complement(4753507..4754124) Escherichia coli 536 4188844 YP_672379.1 CDS ECP_4542 NC_008253.1 4754299 4754613 R major pilu subunit operon regulatory protein PapB complement(4754299..4754613) Escherichia coli 536 4188845 YP_672380.1 CDS ECP_4543 NC_008253.1 4754917 4755195 R hypothetical protein complement(4754917..4755195) Escherichia coli 536 4188846 YP_672381.1 CDS ECP_4544 NC_008253.1 4755317 4755604 D hypothetical protein 4755317..4755604 Escherichia coli 536 4188847 YP_672382.1 CDS ECP_4545 NC_008253.1 4755755 4756123 D hypothetical protein 4755755..4756123 Escherichia coli 536 4188848 YP_672383.1 CDS ECP_4546 NC_008253.1 4756262 4756471 D hypothetical protein 4756262..4756471 Escherichia coli 536 4188849 YP_672384.1 CDS ECP_4547 NC_008253.1 4756629 4756778 D hypothetical protein 4756629..4756778 Escherichia coli 536 4188850 YP_672385.1 CDS ECP_4548 NC_008253.1 4756812 4756970 R hypothetical protein complement(4756812..4756970) Escherichia coli 536 4188851 YP_672386.1 CDS ECP_4549 NC_008253.1 4757034 4757369 D transposase 4757034..4757369 Escherichia coli 536 4188852 YP_672387.1 CDS ECP_4550 NC_008253.1 4757558 4757989 D transposase 4757558..4757989 Escherichia coli 536 4188853 YP_672388.1 CDS ECP_4551 NC_008253.1 4758208 4759284 D transposase 4758208..4759284 Escherichia coli 536 4188854 YP_672389.1 CDS ECP_4552 NC_008253.1 4759367 4759609 D transposase 4759367..4759609 Escherichia coli 536 4188855 YP_672390.1 CDS ECP_4553 NC_008253.1 4759981 4761417 R hemolysin D complement(4759981..4761417) Escherichia coli 536 4188856 YP_672391.1 CDS ECP_4554 NC_008253.1 4761436 4763559 R alpha-hemolysin translocation ATP-binding protein HlyB complement(4761436..4763559) Escherichia coli 536 4188857 YP_672392.1 CDS ECP_4555 NC_008253.1 4763630 4766704 R hemolysin A complement(4763630..4766704) Escherichia coli 536 4188858 YP_672393.1 CDS ECP_4556 NC_008253.1 4766716 4767228 R hemolysin-activating lysine-acyltransferase HlyC complement(4766716..4767228) Escherichia coli 536 4188859 YP_672394.1 CDS ECP_4557 NC_008253.1 4767316 4767537 D hypothetical protein 4767316..4767537 Escherichia coli 536 4188860 YP_672395.1 CDS ECP_4558 NC_008253.1 4767694 4767897 R hypothetical protein complement(4767694..4767897) Escherichia coli 536 4188861 YP_672396.1 CDS ECP_4559 NC_008253.1 4768355 4768618 D hypothetical protein 4768355..4768618 Escherichia coli 536 4188862 YP_672397.1 CDS ECP_4560 NC_008253.1 4768692 4769462 R hypothetical protein complement(4768692..4769462) Escherichia coli 536 4188883 YP_672398.1 CDS ECP_4561 NC_008253.1 4769462 4770061 R hypothetical protein complement(4769462..4770061) Escherichia coli 536 4188884 YP_672399.1 CDS ECP_4562 NC_008253.1 4770202 4770921 D DNA-binding response regulator 4770202..4770921 Escherichia coli 536 4188885 YP_672400.1 CDS ECP_4563 NC_008253.1 4770922 4771773 D hypothetical protein 4770922..4771773 Escherichia coli 536 4188886 YP_672401.1 CDS ECP_4564 NC_008253.1 4771806 4772393 D histidine kinase-like ATPases 4771806..4772393 Escherichia coli 536 4188887 YP_672402.1 CDS ECP_4565 NC_008253.1 4772473 4772841 R transposase-like protein complement(4772473..4772841) Escherichia coli 536 4188888 YP_672403.1 CDS ECP_4566 NC_008253.1 4773155 4773295 R hypothetical protein complement(4773155..4773295) Escherichia coli 536 4188889 YP_672404.1 CDS ECP_4567 NC_008253.1 4773322 4773642 R transposase complement(4773322..4773642) Escherichia coli 536 4188890 YP_672405.1 CDS ECP_4568 NC_008253.1 4773671 4773937 R hypothetical protein complement(4773671..4773937) Escherichia coli 536 4188891 YP_672406.1 CDS ECP_4569 NC_008253.1 4774017 4774265 R hypothetical protein complement(4774017..4774265) Escherichia coli 536 4188892 YP_672407.1 CDS ECP_4570 NC_008253.1 4774618 4776285 R hypothetical protein complement(4774618..4776285) Escherichia coli 536 4188893 YP_672408.1 CDS ECP_4571 NC_008253.1 4776299 4779259 R hypothetical protein complement(4776299..4779259) Escherichia coli 536 4188894 YP_672409.1 CDS ECP_4572 NC_008253.1 4779264 4780310 R modification methylase complement(4779264..4780310) Escherichia coli 536 4188895 YP_672410.1 CDS ECP_4573 NC_008253.1 4780396 4780575 R hypothetical protein complement(4780396..4780575) Escherichia coli 536 4188896 YP_672411.1 CDS ECP_4574 NC_008253.1 4780691 4781047 R hypothetical protein complement(4780691..4781047) Escherichia coli 536 4188897 YP_672412.1 CDS ECP_4575 NC_008253.1 4781057 4781491 R hypothetical protein complement(4781057..4781491) Escherichia coli 536 4188898 YP_672413.1 CDS ECP_4576 NC_008253.1 4781568 4781903 R hypothetical protein complement(4781568..4781903) Escherichia coli 536 4188899 YP_672414.1 CDS ECP_4577 NC_008253.1 4781893 4782162 R hypothetical protein complement(4781893..4782162) Escherichia coli 536 4188900 YP_672415.1 CDS ECP_4578 NC_008253.1 4782205 4782582 R hypothetical protein complement(4782205..4782582) Escherichia coli 536 4188901 YP_672416.1 CDS ECP_4579 NC_008253.1 4782613 4782999 R hypothetical protein complement(4782613..4782999) Escherichia coli 536 4188902 YP_672417.1 CDS ECP_4580 NC_008253.1 4782996 4792724 R hemagglutinin-related protein complement(4782996..4792724) Escherichia coli 536 4189068 YP_672418.1 CDS ECP_4581 NC_008253.1 4792737 4794503 R hemolysin activator HlyB complement(4792737..4794503) Escherichia coli 536 4189069 YP_672419.1 CDS ECP_4582 NC_008253.1 4794562 4794726 R hypothetical protein complement(4794562..4794726) Escherichia coli 536 4189070 YP_672420.1 CDS ECP_4583 NC_008253.1 4794867 4795100 R hypothetical protein complement(4794867..4795100) Escherichia coli 536 4189071 YP_672421.1 CDS ECP_4584 NC_008253.1 4795198 4795857 R hypothetical protein complement(4795198..4795857) Escherichia coli 536 4189072 YP_672422.1 CDS ECP_4585 NC_008253.1 4796089 4796637 R hypothetical protein complement(4796089..4796637) Escherichia coli 536 4189073 YP_672424.1 CDS ECP_4587 NC_008253.1 4796904 4797218 R hypothetical protein complement(4796904..4797218) Escherichia coli 536 4189075 YP_672425.1 CDS ECP_4588 NC_008253.1 4797206 4797898 R hypothetical protein complement(4797206..4797898) Escherichia coli 536 4189076 YP_672426.1 CDS ECP_4589 NC_008253.1 4798013 4798579 R hypothetical protein complement(4798013..4798579) Escherichia coli 536 4189077 YP_672427.1 CDS ECP_4590 NC_008253.1 4799690 4801018 R catalyzes the formation of pyruvate from serine; D-serine dehydratase complement(4799690..4801018) Escherichia coli 536 4189078 YP_672428.1 CDS ECP_4591 NC_008253.1 4801036 4802373 R member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX complement(4801036..4802373) Escherichia coli 536 4189079 YP_672429.1 CDS ECP_4592 NC_008253.1 4802585 4803535 D regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 4802585..4803535 Escherichia coli 536 4189080 YP_672430.1 CDS ECP_4593 NC_008253.1 4803604 4803948 D IS orf 4803604..4803948 Escherichia coli 536 4189081 YP_672431.1 CDS ECP_4594 NC_008253.1 4804188 4804517 R quaternary ammonium compound-resistance protein QacE complement(4804188..4804517) Escherichia coli 536 4189082 YP_672432.1 CDS ECP_4595 NC_008253.1 4804533 4804934 R quaternary ammonium compound-resistance protein QacE complement(4804533..4804934) Escherichia coli 536 4189083 YP_672433.1 CDS ECP_4596 NC_008253.1 4804967 4805632 R hypothetical protein complement(4804967..4805632) Escherichia coli 536 4189084 YP_672434.1 CDS ECP_4597 NC_008253.1 4805644 4806264 R hypothetical protein complement(4805644..4806264) Escherichia coli 536 4189085 YP_672435.1 CDS ECP_4598 NC_008253.1 4806261 4806725 R hypothetical protein complement(4806261..4806725) Escherichia coli 536 4189086 YP_672436.1 CDS ECP_4599 NC_008253.1 4806737 4807684 R hypothetical protein complement(4806737..4807684) Escherichia coli 536 4189469 YP_672437.1 CDS ECP_4600 NC_008253.1 4807736 4811158 R hypothetical protein complement(4807736..4811158) Escherichia coli 536 4189470 YP_672438.1 CDS ECP_4601 NC_008253.1 4811149 4812315 R hypothetical protein complement(4811149..4812315) Escherichia coli 536 4189471 YP_672439.1 CDS ECP_4602 NC_008253.1 4812319 4812576 R hypothetical protein complement(4812319..4812576) Escherichia coli 536 4189472 YP_672440.1 CDS ECP_4603 NC_008253.1 4812603 4814189 R hypothetical protein complement(4812603..4814189) Escherichia coli 536 4189473 YP_672441.1 CDS ECP_4604 NC_008253.1 4814243 4814521 R hypothetical protein complement(4814243..4814521) Escherichia coli 536 4189474 YP_672442.1 CDS ECP_4605 NC_008253.1 4814536 4814820 R hypothetical protein complement(4814536..4814820) Escherichia coli 536 4189475 YP_672443.1 CDS ECP_4606 NC_008253.1 4814838 4815167 R hypothetical protein complement(4814838..4815167) Escherichia coli 536 4189476 YP_672444.1 CDS ECP_4607 NC_008253.1 4815372 4815557 D hypothetical protein 4815372..4815557 Escherichia coli 536 4189477 YP_672445.1 CDS ECP_4608 NC_008253.1 4815636 4816154 R hypothetical protein complement(4815636..4816154) Escherichia coli 536 4189478 YP_672446.1 CDS ECP_4609 NC_008253.1 4816154 4816972 R hypothetical protein complement(4816154..4816972) Escherichia coli 536 4189479 YP_672447.1 CDS ECP_4610 NC_008253.1 4816995 4817573 R transcription regulator protein complement(4816995..4817573) Escherichia coli 536 4189480 YP_672448.1 CDS ECP_4611 NC_008253.1 4817864 4818754 R transposase OrfB protein of insertion sequence IS629 complement(4817864..4818754) Escherichia coli 536 4189481 YP_672449.1 CDS ECP_4612 NC_008253.1 4818751 4819077 R transposase OrfA protein of insertion sequence IS629 complement(4818751..4819077) Escherichia coli 536 4189482 YP_672450.1 CDS ECP_4613 NC_008253.1 4819211 4819429 D hypothetical protein 4819211..4819429 Escherichia coli 536 4189483 YP_672451.1 CDS ECP_4614 NC_008253.1 4819437 4820729 D aminotransferase 4819437..4820729 Escherichia coli 536 4189484 YP_672452.1 CDS ECP_4615 NC_008253.1 4820674 4821912 D Na+/H+ antiporter 4820674..4821912 Escherichia coli 536 4189485 YP_672453.1 CDS ECP_4616 NC_008253.1 4821922 4822704 R transposase/IS protein complement(4821922..4822704) Escherichia coli 536 4189486 YP_672454.1 CDS ECP_4617 NC_008253.1 4822701 4823723 R transposase complement(4822701..4823723) Escherichia coli 536 4189487 YP_672455.1 CDS ECP_4618 NC_008253.1 4823776 4824132 D Na+/H+ antiporter 4823776..4824132 Escherichia coli 536 4189488 YP_672456.1 CDS ECP_4619 NC_008253.1 4824756 4824935 D transposase 4824756..4824935 Escherichia coli 536 4189585 YP_672457.1 CDS ECP_4620 NC_008253.1 4824932 4825411 D hypothetical protein 4824932..4825411 Escherichia coli 536 4189586 YP_672458.1 CDS ECP_4621 NC_008253.1 4825446 4826324 R hypothetical protein complement(4825446..4826324) Escherichia coli 536 4189587 YP_672459.1 CDS ECP_4622 NC_008253.1 4826652 4827383 R hypothetical protein complement(4826652..4827383) Escherichia coli 536 4189588 YP_672460.1 CDS ECP_4623 NC_008253.1 4827427 4827621 R hypothetical protein complement(4827427..4827621) Escherichia coli 536 4189589 YP_672461.1 CDS ECP_4624 NC_008253.1 4827805 4828041 R hypothetical protein complement(4827805..4828041) Escherichia coli 536 4189590 YP_672462.1 CDS ECP_4625 NC_008253.1 4828866 4830089 R hypothetical protein complement(4828866..4830089) Escherichia coli 536 4189591 YP_672463.1 CDS ECP_4626 NC_008253.1 4830190 4831074 D hypothetical protein 4830190..4831074 Escherichia coli 536 4189592 YP_672464.1 CDS ECP_4627 NC_008253.1 4831277 4831957 D hypothetical protein 4831277..4831957 Escherichia coli 536 4189593 YP_672465.1 CDS ECP_4628 NC_008253.1 4832000 4832782 D hypothetical protein 4832000..4832782 Escherichia coli 536 4189594 YP_672466.1 CDS ECP_4629 NC_008253.1 4833111 4833929 D hypothetical protein 4833111..4833929 Escherichia coli 536 4189595 YP_672467.1 CDS ECP_4630 NC_008253.1 4834062 4834505 D hypothetical protein 4834062..4834505 Escherichia coli 536 4189596 YP_672468.1 CDS ECP_4631 NC_008253.1 4834520 4834996 D DNA repair protein 4834520..4834996 Escherichia coli 536 4189597 YP_672469.1 CDS ECP_4632 NC_008253.1 4835083 4835304 D hypothetical protein 4835083..4835304 Escherichia coli 536 4189598 YP_672470.1 CDS ECP_4633 NC_008253.1 4835384 4835752 D hypothetical protein 4835384..4835752 Escherichia coli 536 4189599 YP_672471.1 CDS ECP_4634 NC_008253.1 4835842 4836219 D hypothetical protein 4835842..4836219 Escherichia coli 536 4189600 YP_672472.1 CDS ECP_4635 NC_008253.1 4836270 4836704 D hypothetical protein 4836270..4836704 Escherichia coli 536 4189601 YP_672473.1 CDS ECP_4636 NC_008253.1 4836671 4836913 D hypothetical protein 4836671..4836913 Escherichia coli 536 4189602 YP_672474.1 CDS ECP_4637 NC_008253.1 4836992 4837150 D hypothetical protein 4836992..4837150 Escherichia coli 536 4189603 YP_672475.1 CDS ECP_4638 NC_008253.1 4837169 4837606 D hypothetical protein 4837169..4837606 Escherichia coli 536 4190215 YP_672476.1 CDS ECP_4639 NC_008253.1 4838090 4840138 D hypothetical protein 4838090..4840138 Escherichia coli 536 4190216 YP_672477.1 CDS ECP_4640 NC_008253.1 4840537 4840716 R hypothetical protein complement(4840537..4840716) Escherichia coli 536 4190217 YP_672478.1 CDS ECP_4641 NC_008253.1 4840761 4841633 R hypothetical protein complement(4840761..4841633) Escherichia coli 536 4190218 YP_672479.1 CDS ECP_4642 NC_008253.1 4841845 4842825 R hypothetical protein complement(4841845..4842825) Escherichia coli 536 4190219 YP_672480.1 CDS ECP_4643 NC_008253.1 4842890 4843996 R hypothetical protein complement(4842890..4843996) Escherichia coli 536 4190220 YP_672481.1 CDS ECP_4644 NC_008253.1 4844016 4844732 R hypothetical protein complement(4844016..4844732) Escherichia coli 536 4190221 YP_672482.1 CDS ECP_4645 NC_008253.1 4845529 4845807 R hypothetical protein complement(4845529..4845807) Escherichia coli 536 4190222 YP_672483.1 CDS ECP_4646 NC_008253.1 4846196 4846798 D inversion of on/off regulator of fimA; tyrosine recombinase 4846196..4846798 Escherichia coli 536 4190223 YP_672484.1 CDS ECP_4647 NC_008253.1 4847276 4847872 D inversion of on/off regulator of fimA; tyrosine recombinase 4847276..4847872 Escherichia coli 536 4190224 YP_672485.1 CDS ECP_4648 NC_008253.1 4847951 4848166 R hypothetical protein complement(4847951..4848166) Escherichia coli 536 4190225 YP_672486.1 CDS ECP_4649 NC_008253.1 4848353 4848901 D type-1 fimbrial major subunit 4848353..4848901 Escherichia coli 536 4190226 YP_672487.1 CDS ECP_4650 NC_008253.1 4848867 4849505 D fimbrin-like protein fimI 4848867..4849505 Escherichia coli 536 4190227 YP_672488.1 CDS ECP_4651 NC_008253.1 4849611 4850267 D chaperone protein FimC 4849611..4850267 Escherichia coli 536 4190228 YP_672489.1 CDS ECP_4652 NC_008253.1 4850333 4852969 D outer membrane usher protein FimD 4850333..4852969 Escherichia coli 536 4190229 YP_672490.1 CDS ECP_4653 NC_008253.1 4852979 4853509 D FimF protein 4852979..4853509 Escherichia coli 536 4190230 YP_672491.1 CDS ECP_4654 NC_008253.1 4853522 4854025 D FimG protein 4853522..4854025 Escherichia coli 536 4190231 YP_672492.1 CDS ECP_4655 NC_008253.1 4854036 4854947 D FimH protein 4854036..4854947 Escherichia coli 536 4190232 YP_672493.1 CDS ECP_4656 NC_008253.1 4855257 4855391 D hypothetical protein 4855257..4855391 Escherichia coli 536 4190233 YP_672494.1 CDS ECP_4657 NC_008253.1 4855494 4855649 D hypothetical protein 4855494..4855649 Escherichia coli 536 4190234 YP_672495.1 CDS ECP_4658 NC_008253.1 4855676 4856860 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4855676..4856860 Escherichia coli 536 4190557 YP_672496.1 CDS ECP_4659 NC_008253.1 4856941 4858401 D D-mannonate oxidoreductase 4856941..4858401 Escherichia coli 536 4190558 YP_672497.1 CDS ECP_4660 NC_008253.1 4858616 4859389 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4858616..4859389 Escherichia coli 536 4190559 YP_672498.1 CDS ECP_4661 NC_008253.1 4859803 4860186 D hypothetical protein 4859803..4860186 Escherichia coli 536 4190560 YP_672499.1 CDS ECP_4662 NC_008253.1 4860234 4860575 R hypothetical protein complement(4860234..4860575) Escherichia coli 536 4190561 YP_672500.1 CDS ECP_4663 NC_008253.1 4860612 4861568 R DNA-binding transcriptional regulator complement(4860612..4861568) Escherichia coli 536 4190562 YP_672501.1 CDS ECP_4664 NC_008253.1 4861588 4862760 R isoaspartyl dipeptidase complement(4861588..4862760) Escherichia coli 536 4190563 YP_672502.1 CDS ECP_4665 NC_008253.1 4862773 4863234 R hypothetical protein complement(4862773..4863234) Escherichia coli 536 4190564 YP_672503.1 CDS ECP_4666 NC_008253.1 4863231 4863914 R hypothetical protein complement(4863231..4863914) Escherichia coli 536 4190565 YP_672504.1 CDS ECP_4667 NC_008253.1 4864164 4864718 D in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4864164..4864718 Escherichia coli 536 4190566 YP_672505.1 CDS ECP_4668 NC_008253.1 4864731 4865909 R hypothetical protein complement(4864731..4865909) Escherichia coli 536 4190567 YP_672506.1 CDS ECP_4669 NC_008253.1 4865977 4866945 R hypothetical protein complement(4865977..4866945) Escherichia coli 536 4190568 YP_672507.1 CDS ECP_4670 NC_008253.1 4867156 4867923 R R-phenyllactate dehydratase activator complement(4867156..4867923) Escherichia coli 536 4190569 YP_672508.1 CDS ECP_4671 NC_008253.1 4867933 4869084 R hypothetical protein complement(4867933..4869084) Escherichia coli 536 4190570 YP_672509.1 CDS ECP_4672 NC_008253.1 4869200 4870480 R hypothetical protein complement(4869200..4870480) Escherichia coli 536 4190571 YP_672510.1 CDS ECP_4673 NC_008253.1 4870665 4871585 D hypothetical protein 4870665..4871585 Escherichia coli 536 4190572 YP_672511.1 CDS ECP_4674 NC_008253.1 4871883 4874084 D hypothetical protein 4871883..4874084 Escherichia coli 536 4190573 YP_672512.1 CDS ECP_4675 NC_008253.1 4874131 4874472 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(4874131..4874472) Escherichia coli 536 4190574 YP_672513.1 CDS ECP_4676 NC_008253.1 4874693 4876399 R type I restriction enzyme EcoEI specificity protein complement(4874693..4876399) Escherichia coli 536 4190575 YP_672514.1 CDS ECP_4677 NC_008253.1 4876399 4877904 R type I restriction enzyme EcoEI M protein complement(4876399..4877904) Escherichia coli 536 4190576 YP_672515.1 CDS ECP_4678 NC_008253.1 4877935 4880367 R type I restriction enzyme EcoAI R protein complement(4877935..4880367) Escherichia coli 536 4190577 YP_672516.1 CDS ECP_4679 NC_008253.1 4880645 4882297 D hypothetical protein 4880645..4882297 Escherichia coli 536 4190578 YP_672517.1 CDS ECP_4680 NC_008253.1 4882366 4883322 R GTP-binding protein YjiA complement(4882366..4883322) Escherichia coli 536 4190579 YP_672518.1 CDS ECP_4681 NC_008253.1 4883333 4883536 R hypothetical protein complement(4883333..4883536) Escherichia coli 536 4190580 YP_672519.1 CDS ECP_4682 NC_008253.1 4883654 4885804 R carbon starvation protein complement(4883654..4885804) Escherichia coli 536 4190581 YP_672520.1 CDS ECP_4683 NC_008253.1 4886181 4887845 D serine chemoreceptorprotein; methyl-accepting chemotaxis protein I 4886181..4887845 Escherichia coli 536 4190582 YP_672521.1 CDS ECP_4684 NC_008253.1 4887888 4889159 R C4-dicarboxylate transporter large subunit complement(4887888..4889159) Escherichia coli 536 4190583 YP_672522.1 CDS ECP_4685 NC_008253.1 4889156 4889629 R C4-dicarboxylate transporter small subunit complement(4889156..4889629) Escherichia coli 536 4190584 YP_672523.1 CDS ECP_4686 NC_008253.1 4889693 4890664 R C4-dicarboxylate-binding protein complement(4889693..4890664) Escherichia coli 536 4190585 YP_672524.1 CDS ECP_4687 NC_008253.1 4891334 4893007 D Na(+)/H(+) exchanger YjcE 4891334..4893007 Escherichia coli 536 4190586 YP_672525.1 CDS ECP_4688 NC_008253.1 4893178 4894083 R hypothetical protein complement(4893178..4894083) Escherichia coli 536 4190587 YP_672526.1 CDS ECP_4689 NC_008253.1 4894222 4895244 D zinc-type alcohol dehydrogenase-like protein YjjN 4894222..4895244 Escherichia coli 536 4190588 YP_672527.1 CDS ECP_4690 NC_008253.1 4895384 4897675 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4895384..4897675) Escherichia coli 536 4190589 YP_672528.1 CDS ECP_4691 NC_008253.1 4897929 4898426 R hypothetical protein complement(4897929..4898426) Escherichia coli 536 4190590 YP_672529.1 CDS ECP_4692 NC_008253.1 4898472 4899209 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4898472..4899209) Escherichia coli 536 4190591 YP_672530.1 CDS ECP_4693 NC_008253.1 4899212 4899751 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4899212..4899751) Escherichia coli 536 4190592 YP_672531.1 CDS ECP_4694 NC_008253.1 4899859 4900332 R hypothetical protein complement(4899859..4900332) Escherichia coli 536 4190593 YP_672532.1 CDS ECP_4695 NC_008253.1 4900323 4901093 R hypothetical protein complement(4900323..4901093) Escherichia coli 536 4190594 YP_672533.1 CDS ECP_4696 NC_008253.1 4901788 4902438 D LuxR family transcriptional regulator 4901788..4902438 Escherichia coli 536 4190595 YP_672534.1 CDS ECP_4697 NC_008253.1 4902546 4903073 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4902546..4903073 Escherichia coli 536 4190646 YP_672535.1 CDS ECP_4698 NC_008253.1 4903111 4903899 R ferric hydroximate transport ferric iron reductase complement(4903111..4903899) Escherichia coli 536 4190647 YP_672536.1 CDS ECP_4699 NC_008253.1 4904001 4904276 D hypothetical protein 4904001..4904276 Escherichia coli 536 4190648 YP_672537.1 CDS rsmC NC_008253.1 4904837 4905868 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4904837..4905868) Escherichia coli 536 4190940 YP_672538.1 CDS ECP_4755 NC_008253.1 4905971 4906384 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4905971..4906384 Escherichia coli 536 4190941 YP_672539.1 CDS rimI NC_008253.1 4906353 4906799 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4906353..4906799 Escherichia coli 536 4190942 YP_672540.1 CDS ECP_4757 NC_008253.1 4906814 4907491 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4906814..4907491 Escherichia coli 536 4190943 YP_672541.1 CDS prfC NC_008253.1 4907555 4909171 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4907555..4909171 Escherichia coli 536 4189659 YP_672542.1 CDS ECP_4759 NC_008253.1 4909564 4910169 D hypothetical protein 4909564..4910169 Escherichia coli 536 4189660 YP_672543.1 CDS ECP_4760 NC_008253.1 4910296 4910457 D hypothetical protein 4910296..4910457 Escherichia coli 536 4189661 YP_672544.1 CDS ECP_4761 NC_008253.1 4910579 4911652 D hypothetical protein 4910579..4911652 Escherichia coli 536 4189662 YP_672545.1 CDS ECP_4762 NC_008253.1 4911649 4912428 D deoxyribonuclease YjjV 4911649..4912428 Escherichia coli 536 4189663 YP_672546.1 CDS ECP_4763 NC_008253.1 4912645 4913508 R hypothetical protein complement(4912645..4913508) Escherichia coli 536 4189664 YP_672547.1 CDS ECP_4764 NC_008253.1 4913480 4915030 R hypothetical protein complement(4913480..4915030) Escherichia coli 536 4189665 YP_672548.1 CDS ECP_4765 NC_008253.1 4915288 4916067 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4915288..4916067 Escherichia coli 536 4189666 YP_672549.1 CDS deoA NC_008253.1 4916094 4917467 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4916094..4917467 Escherichia coli 536 4189667 YP_672550.1 CDS ECP_4767 NC_008253.1 4917519 4918742 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4917519..4918742 Escherichia coli 536 4189668 YP_672551.1 CDS deoD NC_008253.1 4918799 4919518 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4918799..4919518 Escherichia coli 536 4189669 YP_672552.1 CDS ECP_4769 NC_008253.1 4919700 4919942 R hypothetical protein complement(4919700..4919942) Escherichia coli 536 4189670 YP_672553.1 CDS lplA NC_008253.1 4919974 4920990 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(4919974..4920990) Escherichia coli 536 4189671 YP_672554.1 CDS ECP_4771 NC_008253.1 4921018 4921662 R hypothetical protein complement(4921018..4921662) Escherichia coli 536 4189672 YP_672555.1 CDS serB NC_008253.1 4921768 4922736 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4921768..4922736 Escherichia coli 536 4189673 YP_672556.1 CDS ECP_4773 NC_008253.1 4922785 4924167 D DNA repair protein sms; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4922785..4924167 Escherichia coli 536 4189674 YP_672557.1 CDS ECP_4774 NC_008253.1 4924188 4925420 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4924188..4925420 Escherichia coli 536 4189675 YP_672558.1 CDS ECP_4775 NC_008253.1 4925545 4925844 D hypothetical protein 4925545..4925844 Escherichia coli 536 4189676 YP_672559.1 CDS ECP_4776 NC_008253.1 4925846 4926130 D MerR family transcriptional regulator 4925846..4926130 Escherichia coli 536 4189677 YP_672560.1 CDS ECP_4777 NC_008253.1 4926186 4927853 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(4926186..4927853) Escherichia coli 536 4189678 YP_672561.1 CDS ECP_4778 NC_008253.1 4928060 4929997 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4928060..4929997 Escherichia coli 536 4190634 YP_672562.1 CDS ECP_4779 NC_008253.1 4930087 4930413 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4930087..4930413 Escherichia coli 536 4190635 YP_672563.1 CDS ECP_4780 NC_008253.1 4930486 4931022 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(4930486..4931022) Escherichia coli 536 4190636 YP_672564.1 CDS ECP_4781 NC_008253.1 4931065 4931712 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4931065..4931712 Escherichia coli 536 4190637 YP_672565.1 CDS ECP_4782 NC_008253.1 4931709 4932578 R right origin-binding protein complement(4931709..4932578) Escherichia coli 536 4190638 YP_672566.1 CDS ECP_4783 NC_008253.1 4932789 4933262 D hypothetical protein 4932789..4933262 Escherichia coli 536 4190639 YP_672567.1 CDS ECP_4784 NC_008253.1 4933275 4933964 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4933275..4933964 Escherichia coli 536 4190640 YP_672568.1 CDS ECP_4785 NC_008253.1 4933964 4935388 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4933964..4935388 Escherichia coli 536 4190641 YP_672569.1 CDS ECP_4786 NC_008253.1 4935446 4936798 D hypothetical protein 4935446..4936798 Escherichia coli 536 4190642 YP_672570.1 CDS ECP_4787 NC_008253.1 4936858 4937574 R dye resistance protein; two-component response regulator complement(4936858..4937574) Escherichia coli 536 4190643 ECP_0211 tRNA ECP_0211 NC_008253.1 229558 229633 D tRNA-Glu 229558..229633 Escherichia coli 536 4191955 ECP_0212 tRNA ECP_0212 NC_008253.1 232996 233072 D tRNA-Asp 232996..233072 Escherichia coli 536 4187362 ECP_0222 tRNA ECP_0222 NC_008253.1 241221 241297 D tRNA-Asp 241221..241297 Escherichia coli 536 4187372 ECP_0273 tRNA ECP_0273 NC_008253.1 294319 294394 D tRNA-Thr 294319..294394 Escherichia coli 536 4190165 ECP_0310 tRNA ECP_0310 NC_008253.1 332397 332473 D tRNA-Arg 332397..332473 Escherichia coli 536 4190524 ECP_0403 tRNA ECP_0403 NC_008253.1 426970 427050 D tRNA-OTHER 426970..427050 Escherichia coli 536 4191764 ECP_0592 tRNA ECP_0592 NC_008253.1 620974 621050 D tRNA-Arg 620974..621050 Escherichia coli 536 4189891 ECP_4731 tRNA ECP_4731 NC_008253.1 723221 723295 R tRNA-Gln complement(723221..723295) Escherichia coli 536 4188987 ECP_4730 tRNA ECP_4730 NC_008253.1 723333 723407 R tRNA-Gln complement(723333..723407) Escherichia coli 536 4188986 ECP_4729 tRNA ECP_4729 NC_008253.1 723456 723532 R tRNA-Met complement(723456..723532) Escherichia coli 536 4188985 ECP_0754 tRNA ECP_0754 NC_008253.1 795927 796002 D tRNA-Lys 795927..796002 Escherichia coli 536 4190669 ECP_0755 tRNA ECP_0755 NC_008253.1 796038 796113 D tRNA-Val 796038..796113 Escherichia coli 536 4190670 ECP_0756 tRNA ECP_0756 NC_008253.1 796116 796191 D tRNA-Lys 796116..796191 Escherichia coli 536 4190671 ECP_0757 tRNA ECP_0757 NC_008253.1 796243 796318 D tRNA-Val 796243..796318 Escherichia coli 536 4190672 ECP_0758 tRNA ECP_0758 NC_008253.1 796322 796397 D tRNA-Lys 796322..796397 Escherichia coli 536 4188078 ECP_0759 tRNA ECP_0759 NC_008253.1 796446 796521 D tRNA-Lys 796446..796521 Escherichia coli 536 4188079 ECP_0760 tRNA ECP_0760 NC_008253.1 796555 796630 D tRNA-Lys 796555..796630 Escherichia coli 536 4188080 ECP_4728 tRNA ECP_4728 NC_008253.1 939676 939763 R tRNA-Ser complement(939676..939763) Escherichia coli 536 4188984 ECP_4727 tRNA ECP_4727 NC_008253.1 1034999 1035086 R tRNA-Ser complement(1034999..1035086) Escherichia coli 536 4188983 ECP_4726 tRNA ECP_4726 NC_008253.1 1088445 1088532 R tRNA-Ser complement(1088445..1088532) Escherichia coli 536 4188982 ECP_4725 tRNA ECP_4725 NC_008253.1 1310055 1310139 R tRNA-Tyr complement(1310055..1310139) Escherichia coli 536 4191033 ECP_4724 tRNA ECP_4724 NC_008253.1 1310173 1310257 R tRNA-Tyr complement(1310173..1310257) Escherichia coli 536 4191032 ECP_1612 tRNA ECP_1612 NC_008253.1 1661394 1661470 D tRNA-Val 1661394..1661470 Escherichia coli 536 4190422 ECP_1613 tRNA ECP_1613 NC_008253.1 1661475 1661551 D tRNA-Val 1661475..1661551 Escherichia coli 536 4190423 ECP_4723 tRNA ECP_4723 NC_008253.1 1900668 1900754 R tRNA-Leu complement(1900668..1900754) Escherichia coli 536 4191031 ECP_4722 tRNA ECP_4722 NC_008253.1 1900767 1900840 R tRNA-Cys complement(1900767..1900840) Escherichia coli 536 4191030 ECP_4721 tRNA ECP_4721 NC_008253.1 1900894 1900969 R tRNA-Gly complement(1900894..1900969) Escherichia coli 536 4191029 ECP_4720 tRNA ECP_4720 NC_008253.1 1970000 1970089 R tRNA-Ser complement(1970000..1970089) Escherichia coli 536 4191028 ECP_1935 tRNA ECP_1935 NC_008253.1 1971081 1971156 D tRNA-Asn 1971081..1971156 Escherichia coli 536 4187463 ECP_4719 tRNA ECP_4719 NC_008253.1 2010971 2011046 R tRNA-Asn complement(2010971..2011046) Escherichia coli 536 4191027 ECP_4718 tRNA ECP_4718 NC_008253.1 2013380 2013455 R tRNA-Asn complement(2013380..2013455) Escherichia coli 536 4191026 ECP_1961 tRNA ECP_1961 NC_008253.1 2015204 2015279 D tRNA-Asn 2015204..2015279 Escherichia coli 536 4191247 ECP_2230 tRNA ECP_2230 NC_008253.1 2327058 2327134 D tRNA-Pro 2327058..2327134 Escherichia coli 536 4189294 ECP_2385 tRNA ECP_2385 NC_008253.1 2496761 2496835 D tRNA-Arg 2496761..2496835 Escherichia coli 536 4189622 ECP_4717 tRNA ECP_4717 NC_008253.1 2540120 2540195 R tRNA-Ala complement(2540120..2540195) Escherichia coli 536 4191025 ECP_4716 tRNA ECP_4716 NC_008253.1 2540235 2540310 R tRNA-Ala complement(2540235..2540310) Escherichia coli 536 4190721 ECP_2423 tRNA ECP_2423 NC_008253.1 2543009 2543084 D tRNA-Val 2543009..2543084 Escherichia coli 536 4191541 ECP_2424 tRNA ECP_2424 NC_008253.1 2543129 2543204 D tRNA-Val 2543129..2543204 Escherichia coli 536 4191542 ECP_2425 tRNA ECP_2425 NC_008253.1 2543251 2543326 D tRNA-Val 2543251..2543326 Escherichia coli 536 4191543 ECP_2426 tRNA ECP_2426 NC_008253.1 2543331 2543406 D tRNA-Lys 2543331..2543406 Escherichia coli 536 4191544 ECP_4715 tRNA ECP_4715 NC_008253.1 2737320 2737395 R tRNA-Glu complement(2737320..2737395) Escherichia coli 536 4190720 ECP_4714 tRNA ECP_4714 NC_008253.1 2794935 2795011 R tRNA-Arg complement(2794935..2795011) Escherichia coli 536 4190719 ECP_4713 tRNA ECP_4713 NC_008253.1 2795075 2795151 R tRNA-Arg complement(2795075..2795151) Escherichia coli 536 4190718 ECP_4712 tRNA ECP_4712 NC_008253.1 2795214 2795290 R tRNA-Arg complement(2795214..2795290) Escherichia coli 536 4190717 ECP_4711 tRNA ECP_4711 NC_008253.1 2795355 2795431 R tRNA-Arg complement(2795355..2795431) Escherichia coli 536 4190716 ECP_4710 tRNA ECP_4710 NC_008253.1 2795435 2795527 R tRNA-Ser complement(2795435..2795527) Escherichia coli 536 4190715 ECP_2797 tRNA ECP_2797 NC_008253.1 2940684 2940760 D tRNA-Met 2940684..2940760 Escherichia coli 536 4187408 ECP_2798 tRNA ECP_2798 NC_008253.1 2940794 2940870 D tRNA-Met 2940794..2940870 Escherichia coli 536 4187409 ECP_2799 tRNA ECP_2799 NC_008253.1 2940904 2940980 D tRNA-Met 2940904..2940980 Escherichia coli 536 4187410 ECP_4709 tRNA ECP_4709 NC_008253.1 3018048 3018121 R tRNA-Gly complement(3018048..3018121) Escherichia coli 536 4190714 ECP_2961 tRNA ECP_2961 NC_008253.1 3128084 3128159 D tRNA-Phe 3128084..3128159 Escherichia coli 536 4191096 ECP_3159 tRNA ECP_3159 NC_008253.1 3327284 3327359 D tRNA-Met 3327284..3327359 Escherichia coli 536 4188648 ECP_4708 tRNA ECP_4708 NC_008253.1 3428663 3428739 R tRNA-Met complement(3428663..3428739) Escherichia coli 536 4190713 ECP_4707 tRNA ECP_4707 NC_008253.1 3432519 3432605 R tRNA-Leu complement(3432519..3432605) Escherichia coli 536 4190656 ECP_4706 tRNA ECP_4706 NC_008253.1 3533303 3533378 R tRNA-Thr complement(3533303..3533378) Escherichia coli 536 4190655 ECP_4705 tRNA ECP_4705 NC_008253.1 3536702 3536777 R tRNA-Glu complement(3536702..3536777) Escherichia coli 536 4190654 ECP_4704 tRNA ECP_4704 NC_008253.1 3822847 3822923 R tRNA-Pro complement(3822847..3822923) Escherichia coli 536 4190653 ECP_3764 tRNA ECP_3764 NC_008253.1 3947789 3947879 D tRNA-Sec 3947789..3947879 Escherichia coli 536 4191463 ECP_3956 tRNA ECP_3956 NC_008253.1 4127225 4127300 D tRNA-Glu 4127225..4127300 Escherichia coli 536 4188607 ECP_3957 tRNA ECP_3957 NC_008253.1 4130662 4130738 D tRNA-Asp 4130662..4130738 Escherichia coli 536 4188608 ECP_3958 tRNA ECP_3958 NC_008253.1 4130747 4130822 D tRNA-Trp 4130747..4130822 Escherichia coli 536 4188609 ECP_3988 tRNA ECP_3988 NC_008253.1 4165293 4165369 D tRNA-Arg 4165293..4165369 Escherichia coli 536 4190964 ECP_3989 tRNA ECP_3989 NC_008253.1 4165428 4165503 D tRNA-His 4165428..4165503 Escherichia coli 536 4190965 ECP_3990 tRNA ECP_3990 NC_008253.1 4165524 4165610 D tRNA-Leu 4165524..4165610 Escherichia coli 536 4190966 ECP_3991 tRNA ECP_3991 NC_008253.1 4165653 4165729 D tRNA-Pro 4165653..4165729 Escherichia coli 536 4190967 ECP_4064 tRNA ECP_4064 NC_008253.1 4243002 4243078 D tRNA-Ile 4243002..4243078 Escherichia coli 536 4187703 ECP_4065 tRNA ECP_4065 NC_008253.1 4243121 4243196 D tRNA-Ala 4243121..4243196 Escherichia coli 536 4187704 ECP_4185 tRNA ECP_4185 NC_008253.1 4380495 4380570 D tRNA-Glu 4380495..4380570 Escherichia coli 536 4189213 ECP_4189 tRNA ECP_4189 NC_008253.1 4387346 4387421 D tRNA-Thr 4387346..4387421 Escherichia coli 536 4189217 ECP_4190 tRNA ECP_4190 NC_008253.1 4387430 4387514 D tRNA-Tyr 4387430..4387514 Escherichia coli 536 4189218 ECP_4191 tRNA ECP_4191 NC_008253.1 4387631 4387705 D tRNA-Gly 4387631..4387705 Escherichia coli 536 4188244 ECP_4192 tRNA ECP_4192 NC_008253.1 4387712 4387787 D tRNA-Thr 4387712..4387787 Escherichia coli 536 4188245 ECP_4220 tRNA ECP_4220 NC_008253.1 4420666 4420741 D tRNA-Glu 4420666..4420741 Escherichia coli 536 4188692 ECP_4703 tRNA ECP_4703 NC_008253.1 4593023 4593098 R tRNA-Phe complement(4593023..4593098) Escherichia coli 536 4190652 ECP_4408 tRNA ECP_4408 NC_008253.1 4621978 4622053 D tRNA-Gly 4621978..4622053 Escherichia coli 536 4190212 ECP_4409 tRNA ECP_4409 NC_008253.1 4622090 4622165 D tRNA-Gly 4622090..4622165 Escherichia coli 536 4190213 ECP_4410 tRNA ECP_4410 NC_008253.1 4622201 4622276 D tRNA-Gly 4622201..4622276 Escherichia coli 536 4190214 ECP_4520 tRNA ECP_4520 NC_008253.1 4735147 4735231 D tRNA-Leu 4735147..4735231 Escherichia coli 536 4188584 ECP_4702 tRNA ECP_4702 NC_008253.1 4904315 4904401 R tRNA-Leu complement(4904315..4904401) Escherichia coli 536 4190651 ECP_4701 tRNA ECP_4701 NC_008253.1 4904436 4904522 R tRNA-Leu complement(4904436..4904522) Escherichia coli 536 4190650 ECP_4700 tRNA ECP_4700 NC_008253.1 4904551 4904637 R tRNA-Leu complement(4904551..4904637) Escherichia coli 536 4190649 ECP_4736 rRNA ECP_4736 NC_008253.1 227931 229472 D 16S ribosomal RNA 227931..229472 Escherichia coli 536 4191015 ECP_4735 rRNA ECP_4735 NC_008253.1 229827 232730 D 23S ribosomal RNA 229827..232730 Escherichia coli 536 4188991 ECP_4737 rRNA ECP_4737 NC_008253.1 232824 232943 D 5S ribosomal RNA 232824..232943 Escherichia coli 536 4191016 ECP_4734 rRNA ECP_4734 NC_008253.1 2734010 2734129 R 5S ribosomal RNA complement(2734010..2734129) Escherichia coli 536 4188990 ECP_4733 rRNA ECP_4733 NC_008253.1 2734223 2737126 R 23S ribosomal RNA complement(2734223..2737126) Escherichia coli 536 4188989 ECP_4732 rRNA ECP_4732 NC_008253.1 2737481 2739023 R 16S ribosomal RNA complement(2737481..2739023) Escherichia coli 536 4188988 ECP_4747 rRNA ECP_4747 NC_008253.1 3533150 3533262 R 5S ribosomal RNA complement(3533150..3533262) Escherichia coli 536 4190933 ECP_4746 rRNA ECP_4746 NC_008253.1 3533391 3533510 R 5S ribosomal RNA complement(3533391..3533510) Escherichia coli 536 4190932 ECP_4744 rRNA ECP_4744 NC_008253.1 3533604 3536508 R 23S ribosomal RNA complement(3533604..3536508) Escherichia coli 536 4191023 ECP_4745 rRNA ECP_4745 NC_008253.1 3536863 3538404 R 16S ribosomal RNA complement(3536863..3538404) Escherichia coli 536 4191024 ECP_4749 rRNA ECP_4749 NC_008253.1 4125597 4127139 D 16S ribosomal RNA 4125597..4127139 Escherichia coli 536 4190935 ECP_4748 rRNA ECP_4748 NC_008253.1 4127494 4130397 D 23S ribosomal RNA 4127494..4130397 Escherichia coli 536 4190934 ECP_4750 rRNA ECP_4750 NC_008253.1 4130491 4130610 D 5S ribosomal RNA 4130491..4130610 Escherichia coli 536 4190936 ECP_4742 rRNA ECP_4742 NC_008253.1 4241392 4242933 D 16S ribosomal RNA 4241392..4242933 Escherichia coli 536 4191021 ECP_4741 rRNA ECP_4741 NC_008253.1 4243380 4246283 D 23S ribosomal RNA 4243380..4246283 Escherichia coli 536 4191020 ECP_4743 rRNA ECP_4743 NC_008253.1 4246377 4246496 D 5S ribosomal RNA 4246377..4246496 Escherichia coli 536 4191022 ECP_4752 rRNA ECP_4752 NC_008253.1 4378773 4380323 D 16S ribosomal RNA 4378773..4380323 Escherichia coli 536 4190938 ECP_4751 rRNA ECP_4751 NC_008253.1 4380764 4383667 D 23S ribosomal RNA 4380764..4383667 Escherichia coli 536 4190937 ECP_4753 rRNA ECP_4753 NC_008253.1 4383761 4383880 D 5S ribosomal RNA 4383761..4383880 Escherichia coli 536 4190939 ECP_4739 rRNA ECP_4739 NC_008253.1 4419039 4420580 D 16S ribosomal RNA 4419039..4420580 Escherichia coli 536 4191018 ECP_4738 rRNA ECP_4738 NC_008253.1 4420935 4423838 D 23S ribosomal RNA 4420935..4423838 Escherichia coli 536 4191017 ECP_4740 rRNA ECP_4740 NC_008253.1 4423932 4424051 D 5S ribosomal RNA 4423932..4424051 Escherichia coli 536 4191019