-- dump date 20140619_081201 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_851209.2 229775982 4491344 317..2779 1 NC_008563.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2779 thrA 4491344 thrA Escherichia coli APEC O1 bifunctional aspartokinase I/homoserine dehydrogenase I YP_851209.2 317 D 405955 CDS YP_851210.1 117622297 4491345 2781..3713 1 NC_008563.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3713 thrB 4491345 thrB Escherichia coli APEC O1 homoserine kinase YP_851210.1 2781 D 405955 CDS YP_851211.1 117622298 4491346 3714..5000 1 NC_008563.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5000 thrC 4491346 thrC Escherichia coli APEC O1 threonine synthase YP_851211.1 3714 D 405955 CDS YP_851212.1 117622299 4491347 5214..5510 1 NC_008563.1 hypothetical protein 5510 yaaX 4491347 yaaX Escherichia coli APEC O1 hypothetical protein YP_851212.1 5214 D 405955 CDS YP_851213.1 117622300 4491348 complement(5550..6326) 1 NC_008563.1 hypothetical protein 6326 yaaA 4491348 yaaA Escherichia coli APEC O1 hypothetical protein YP_851213.1 5550 R 405955 CDS YP_851214.1 117622301 4491349 complement(6396..7826) 1 NC_008563.1 transporter YaaJ 7826 yaaJ 4491349 yaaJ Escherichia coli APEC O1 transporter YaaJ YP_851214.1 6396 R 405955 CDS YP_851215.2 162317588 4491350 8105..9058 1 NC_008563.1 transaldolase B 9058 talB 4491350 talB Escherichia coli APEC O1 transaldolase B YP_851215.2 8105 D 405955 CDS YP_851216.1 117622303 4491351 9173..9760 1 NC_008563.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9760 mogA 4491351 mogA Escherichia coli APEC O1 molybdenum cofactor biosynthesis protein MogA YP_851216.1 9173 D 405955 CDS YP_851217.1 117622304 4491352 complement(9965..10531) 1 NC_008563.1 hypothetical protein 10531 yaaH 4491352 yaaH Escherichia coli APEC O1 hypothetical protein YP_851217.1 9965 R 405955 CDS YP_851218.1 117622305 4491353 complement(10680..11393) 1 NC_008563.1 hypothetical protein 11393 yaaW 4491353 yaaW Escherichia coli APEC O1 hypothetical protein YP_851218.1 10680 R 405955 CDS YP_851219.1 117622306 4491354 complement(11419..11823) 1 NC_008563.1 hypothetical protein 11823 yaaI 4491354 yaaI Escherichia coli APEC O1 hypothetical protein YP_851219.1 11419 R 405955 CDS YP_851220.1 117622307 4491355 12195..14111 1 NC_008563.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14111 dnaK 4491355 dnaK Escherichia coli APEC O1 molecular chaperone DnaK YP_851220.1 12195 D 405955 CDS YP_851221.2 229775981 4491356 14200..15330 1 NC_008563.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 15330 dnaJ 4491356 dnaJ Escherichia coli APEC O1 chaperone protein DnaJ YP_851221.2 14200 D 405955 CDS YP_851222.1 117622309 4491357 16199..16960 1 NC_008563.1 hypothetical protein 16960 4491357 APECO1_1963 Escherichia coli APEC O1 hypothetical protein YP_851222.1 16199 D 405955 CDS YP_851223.1 117622310 4491358 16950..18473 1 NC_008563.1 arylsulfatase 18473 aslA 4491358 aslA Escherichia coli APEC O1 arylsulfatase YP_851223.1 16950 D 405955 CDS YP_851224.1 117622311 4491359 18596..19861 1 NC_008563.1 hypothetical protein 19861 4491359 APECO1_1961 Escherichia coli APEC O1 hypothetical protein YP_851224.1 18596 D 405955 CDS YP_851225.1 117622312 4491360 20096..21262 1 NC_008563.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 21262 nhaA 4491360 nhaA Escherichia coli APEC O1 pH-dependent sodium/proton antiporter YP_851225.1 20096 D 405955 CDS YP_851226.1 117622313 4491361 21322..22227 1 NC_008563.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 22227 nhaR 4491361 nhaR Escherichia coli APEC O1 transcriptional activator NhaR YP_851226.1 21322 D 405955 CDS YP_851227.1 117622314 4491362 22915..23856 1 NC_008563.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 23856 ribF 4491362 ribF Escherichia coli APEC O1 bifunctional riboflavin kinase/FMN adenylyltransferase YP_851227.1 22915 D 405955 CDS YP_851228.1 117622315 4491420 23899..26715 1 NC_008563.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 26715 ileS 4491420 ileS Escherichia coli APEC O1 isoleucyl-tRNA synthetase YP_851228.1 23899 D 405955 CDS YP_851229.1 117622316 4491421 26715..27209 1 NC_008563.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 27209 lspA 4491421 lspA Escherichia coli APEC O1 lipoprotein signal peptidase YP_851229.1 26715 D 405955 CDS YP_851230.1 117622317 4491422 27317..27766 1 NC_008563.1 FKBP-type peptidyl-prolyl cis-trans isomerase 27766 slpA 4491422 slpA Escherichia coli APEC O1 FKBP-type peptidyl-prolyl cis-trans isomerase YP_851230.1 27317 D 405955 CDS YP_851231.1 117622318 4491423 27768..28718 1 NC_008563.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 28718 ispH 4491423 ispH Escherichia coli APEC O1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_851231.1 27768 D 405955 CDS YP_851232.1 117622319 4491424 28784..29698 1 NC_008563.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 29698 rihC 4491424 rihC Escherichia coli APEC O1 ribonucleoside hydrolase RihC YP_851232.1 28784 D 405955 CDS YP_851233.1 117622320 4491425 29721..30086 1 NC_008563.1 hypothetical protein 30086 4491425 APECO1_1952 Escherichia coli APEC O1 hypothetical protein YP_851233.1 29721 D 405955 CDS YP_851234.1 117622321 4491426 30247..31068 1 NC_008563.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 31068 dapB 4491426 dapB Escherichia coli APEC O1 dihydrodipicolinate reductase YP_851234.1 30247 D 405955 CDS YP_851235.1 117622322 4491427 31497..32672 1 NC_008563.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 32672 carA 4491427 carA Escherichia coli APEC O1 carbamoyl phosphate synthase small subunit YP_851235.1 31497 D 405955 CDS YP_851236.1 117622323 4491428 32690..35911 1 NC_008563.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 35911 carB 4491428 carB Escherichia coli APEC O1 carbamoyl phosphate synthase large subunit YP_851236.1 32690 D 405955 CDS YP_851237.1 117622324 4491429 36135..36593 1 NC_008563.1 IS200-related; transposase 36593 4491429 APECO1_1948 Escherichia coli APEC O1 transposase YP_851237.1 36135 D 405955 CDS YP_851238.1 117622325 4491430 36778..37278 1 NC_008563.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; CaiF family transcriptional regulator 37278 caiF 4491430 caiF Escherichia coli APEC O1 CaiF family transcriptional regulator YP_851238.1 36778 D 405955 CDS YP_851239.1 117622326 4491431 complement(37397..38008) 1 NC_008563.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 38008 caiE 4491431 caiE Escherichia coli APEC O1 carnitine operon protein CaiE YP_851239.1 37397 R 405955 CDS YP_851240.2 229775980 4491432 complement(37993..38778) 1 NC_008563.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 38778 caiD 4491432 caiD Escherichia coli APEC O1 carnitinyl-CoA dehydratase YP_851240.2 37993 R 405955 CDS YP_851241.1 117622328 4491433 complement(38887..40455) 1 NC_008563.1 crotonobetaine/carnitine-CoA ligase 40455 caiC 4491433 caiC Escherichia coli APEC O1 crotonobetaine/carnitine-CoA ligase YP_851241.1 38887 R 405955 CDS YP_851242.1 117622329 4491434 complement(40513..41730) 1 NC_008563.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 41730 caiB 4491434 caiB Escherichia coli APEC O1 crotonobetainyl-CoA:carnitine CoA-transferase YP_851242.1 40513 R 405955 CDS YP_851243.1 117622330 4491435 complement(41858..43000) 1 NC_008563.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 43000 caiA 4491435 caiA Escherichia coli APEC O1 crotonobetainyl-CoA dehydrogenase YP_851243.1 41858 R 405955 CDS YP_851244.1 117622331 4491436 complement(43031..44545) 1 NC_008563.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 44545 caiT 4491436 caiT Escherichia coli APEC O1 L-carnitine/gamma-butyrobetaine antiporter YP_851244.1 43031 R 405955 CDS YP_851245.1 117622332 4491437 44955..45788 1 NC_008563.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45788 fixA 4491437 fixA Escherichia coli APEC O1 electron transfer flavoprotein FixA YP_851245.1 44955 D 405955 CDS YP_851246.1 117622333 4491438 45803..46744 1 NC_008563.1 involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 46744 fixB 4491438 fixB Escherichia coli APEC O1 electron transfer flavoprotein FixB YP_851246.1 45803 D 405955 CDS YP_851247.1 117622334 4491439 46795..48081 1 NC_008563.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 48081 ydiS 4491439 ydiS Escherichia coli APEC O1 oxidoreductase FixC YP_851247.1 46795 D 405955 CDS YP_851248.1 117622335 4493283 48424..49755 1 NC_008563.1 metabolite transport protein YaaU 49755 yaaU 4493283 yaaU Escherichia coli APEC O1 metabolite transport protein YaaU YP_851248.1 48424 D 405955 CDS YP_851249.1 117622336 4493284 49863..50393 1 NC_008563.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 50393 yabF 4493284 yabF Escherichia coli APEC O1 glutathione-regulated potassium-efflux system ancillary protein KefF YP_851249.1 49863 D 405955 CDS YP_851250.1 117622337 4493285 50314..52248 1 NC_008563.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52248 kefC 4493285 kefC Escherichia coli APEC O1 glutathione-regulated potassium-efflux system protein KefC YP_851250.1 50314 D 405955 CDS YP_851251.1 117622338 4493286 52305..52919 1 NC_008563.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52919 folA 4493286 folA Escherichia coli APEC O1 dihydrofolate reductase YP_851251.1 52305 D 405955 CDS YP_851252.1 117622339 4493287 complement(53553..54401) 1 NC_008563.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 54401 apaH 4493287 apaH Escherichia coli APEC O1 diadenosine tetraphosphatase YP_851252.1 53553 R 405955 CDS YP_851253.1 117622340 4493288 complement(54408..54785) 1 NC_008563.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 54785 apaG 4493288 apaG Escherichia coli APEC O1 ApaG protein YP_851253.1 54408 R 405955 CDS YP_851254.1 117622341 4493289 complement(54788..55609) 1 NC_008563.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 55609 ksgA 4493289 ksgA Escherichia coli APEC O1 dimethyladenosine transferase YP_851254.1 54788 R 405955 CDS YP_851255.1 117622342 4493290 complement(55606..56595) 1 NC_008563.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 56595 pdxA 4493290 pdxA Escherichia coli APEC O1 4-hydroxythreonine-4-phosphate dehydrogenase YP_851255.1 55606 R 405955 CDS YP_851256.1 117622343 4493291 complement(56595..57881) 1 NC_008563.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 57881 surA 4493291 surA Escherichia coli APEC O1 peptidyl-prolyl cis-trans isomerase SurA YP_851256.1 56595 R 405955 CDS YP_851257.1 117622344 4493292 complement(57934..60288) 1 NC_008563.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 60288 imp 4493292 imp Escherichia coli APEC O1 organic solvent tolerance protein YP_851257.1 57934 R 405955 CDS YP_851258.1 117622345 4493293 60450..61358 1 NC_008563.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 61358 djlA 4493293 djlA Escherichia coli APEC O1 Dna-J like membrane chaperone protein YP_851258.1 60450 D 405955 CDS YP_851259.1 117622346 4493294 complement(61508..62167) 1 NC_008563.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 62167 rluA 4493294 rluA Escherichia coli APEC O1 23S rRNA/tRNA pseudouridine synthase A YP_851259.1 61508 R 405955 CDS YP_851260.1 117622347 4493295 complement(62179..65085) 1 NC_008563.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 65085 hepA 4493295 hepA Escherichia coli APEC O1 ATP-dependent helicase HepA YP_851260.1 62179 R 405955 CDS YP_851261.1 117622348 4493296 complement(65249..67600) 1 NC_008563.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 67600 polB 4493296 polB Escherichia coli APEC O1 DNA polymerase II YP_851261.1 65249 R 405955 CDS YP_851262.1 117622349 4493297 complement(67675..68370) 1 NC_008563.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 68370 araD 4493297 araD Escherichia coli APEC O1 L-ribulose-5-phosphate 4-epimerase YP_851262.1 67675 R 405955 CDS YP_851263.1 117622350 4493298 complement(68655..70157) 1 NC_008563.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 70157 araA 4493298 araA Escherichia coli APEC O1 L-arabinose isomerase YP_851263.1 68655 R 405955 CDS YP_851264.1 117622351 4493299 complement(70168..71868) 1 NC_008563.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 71868 araB 4493299 araB Escherichia coli APEC O1 ribulokinase YP_851264.1 70168 R 405955 CDS YP_851265.1 117622352 4493300 72156..73052 1 NC_008563.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; AraC family transcriptional regulator 73052 araC 4493300 araC Escherichia coli APEC O1 AraC family transcriptional regulator YP_851265.1 72156 D 405955 CDS YP_851266.1 117622353 4493301 73842..74414 1 NC_008563.1 hypothetical protein 74414 4493301 APECO1_1919 Escherichia coli APEC O1 hypothetical protein YP_851266.1 73842 D 405955 CDS YP_851267.1 117622354 4493185 74421..74843 1 NC_008563.1 hypothetical protein 74843 4493185 APECO1_1918 Escherichia coli APEC O1 hypothetical protein YP_851267.1 74421 D 405955 CDS YP_851268.1 117622355 4493186 74998..75762 1 NC_008563.1 integral membrane protein YabI 75762 yabI 4493186 yabI Escherichia coli APEC O1 integral membrane protein YabI YP_851268.1 74998 D 405955 CDS YP_851269.1 117622356 4493187 complement(75876..76574) 1 NC_008563.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 76574 thiQ 4493187 thiQ Escherichia coli APEC O1 thiamine transporter ATP-binding subunit YP_851269.1 75876 R 405955 CDS YP_851270.1 117622357 4493188 complement(76558..78168) 1 NC_008563.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 78168 thiP 4493188 thiP Escherichia coli APEC O1 thiamine transporter membrane protein YP_851270.1 76558 R 405955 CDS YP_851271.1 117622358 4493189 complement(78144..79139) 1 NC_008563.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 79139 tbpA 4493189 tbpA Escherichia coli APEC O1 thiamine transporter substrate binding subunit YP_851271.1 78144 R 405955 CDS YP_851272.1 117622359 4493190 complement(79291..80946) 1 NC_008563.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 80946 sgrR 4493190 sgrR Escherichia coli APEC O1 transcriptional regulator SgrR YP_851272.1 79291 R 405955 CDS YP_851273.1 117622360 4493191 complement(81274..81879) 1 NC_008563.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 81879 leuD 4493191 leuD Escherichia coli APEC O1 isopropylmalate isomerase small subunit YP_851273.1 81274 R 405955 CDS YP_851274.1 117622361 4493195 complement(81890..83290) 1 NC_008563.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 83290 leuC 4493195 leuC Escherichia coli APEC O1 isopropylmalate isomerase large subunit YP_851274.1 81890 R 405955 CDS YP_851275.1 117622362 4493196 complement(83293..84387) 1 NC_008563.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 84387 leuB 4493196 leuB Escherichia coli APEC O1 3-isopropylmalate dehydrogenase YP_851275.1 83293 R 405955 CDS YP_851276.1 117622363 4493197 complement(84384..85955) 1 NC_008563.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 85955 leuA 4493197 leuA Escherichia coli APEC O1 2-isopropylmalate synthase YP_851276.1 84384 R 405955 CDS YP_851277.1 117622364 4493198 86707..87735 1 NC_008563.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 87735 leuO 4493198 leuO Escherichia coli APEC O1 leucine transcriptional activator YP_851277.1 86707 D 405955 CDS YP_851278.1 117622365 4493199 87963..89777 1 NC_008563.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 89777 ilvI 4493199 ilvI Escherichia coli APEC O1 acetolactate synthase 3 catalytic subunit YP_851278.1 87963 D 405955 CDS YP_851279.1 117622366 4493200 89750..90271 1 NC_008563.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 90271 ilvH 4493200 ilvH Escherichia coli APEC O1 acetolactate synthase 3 regulatory subunit YP_851279.1 89750 D 405955 CDS YP_851280.1 117622367 4493201 90451..91455 1 NC_008563.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 91455 fruR 4493201 fruR Escherichia coli APEC O1 DNA-binding transcriptional regulator FruR YP_851280.1 90451 D 405955 CDS YP_851281.1 117622368 4493202 92418..93458 1 NC_008563.1 S-adenosyl-methyltransferase MraW 93458 mraW 4493202 mraW Escherichia coli APEC O1 S-adenosyl-methyltransferase MraW YP_851281.1 92418 D 405955 CDS YP_851282.1 117622369 4493203 93455..93820 1 NC_008563.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 93820 ftsL 4493203 ftsL Escherichia coli APEC O1 cell division protein FtsL YP_851282.1 93455 D 405955 CDS YP_851283.1 117622370 4493204 93836..95602 1 NC_008563.1 peptidoglycan synthetase FtsI 95602 ftsI 4493204 ftsI Escherichia coli APEC O1 peptidoglycan synthetase FtsI YP_851283.1 93836 D 405955 CDS YP_851284.1 117622371 4493067 95589..97076 1 NC_008563.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 97076 murE 4493067 murE Escherichia coli APEC O1 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_851284.1 95589 D 405955 CDS YP_851285.1 117622372 4493068 97073..98431 1 NC_008563.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 98431 murF 4493068 murF Escherichia coli APEC O1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_851285.1 97073 D 405955 CDS YP_851286.1 117622373 4493069 98425..99507 1 NC_008563.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 99507 mraY 4493069 mraY Escherichia coli APEC O1 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_851286.1 98425 D 405955 CDS YP_851287.1 117622374 4493070 99510..100826 1 NC_008563.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 100826 murD 4493070 murD Escherichia coli APEC O1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_851287.1 99510 D 405955 CDS YP_851288.1 117622375 4493071 100826..102070 1 NC_008563.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 102070 ftsW 4493071 ftsW Escherichia coli APEC O1 cell division protein FtsW YP_851288.1 100826 D 405955 CDS YP_851289.1 117622376 4493072 102067..103134 1 NC_008563.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 103134 murG 4493072 murG Escherichia coli APEC O1 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_851289.1 102067 D 405955 CDS YP_851290.1 117622377 4493073 103188..104663 1 NC_008563.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 104663 murC 4493073 murC Escherichia coli APEC O1 UDP-N-acetylmuramate--L-alanine ligase YP_851290.1 103188 D 405955 CDS YP_851291.1 117622378 4493074 104656..105576 1 NC_008563.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 105576 ddl 4493074 ddl Escherichia coli APEC O1 D-alanine--D-alanine ligase YP_851291.1 104656 D 405955 CDS YP_851292.1 117622379 4493075 105578..106408 1 NC_008563.1 involved in septum formation; cell division protein FtsQ 106408 ftsQ 4493075 ftsQ Escherichia coli APEC O1 cell division protein FtsQ YP_851292.1 105578 D 405955 CDS YP_851293.1 117622380 4493076 106405..107667 1 NC_008563.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 107667 ftsA 4493076 ftsA Escherichia coli APEC O1 cell division protein FtsA YP_851293.1 106405 D 405955 CDS YP_851294.1 117622381 4493077 107728..108879 1 NC_008563.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 108879 ftsZ 4493077 ftsZ Escherichia coli APEC O1 cell division protein FtsZ YP_851294.1 107728 D 405955 CDS YP_851295.1 117622382 4493078 108980..109897 1 NC_008563.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 109897 lpxC 4493078 lpxC Escherichia coli APEC O1 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_851295.1 108980 D 405955 CDS YP_851296.1 117622383 4493079 110053..110640 1 NC_008563.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 110640 secM 4493079 secM Escherichia coli APEC O1 SecA regulator SecM YP_851296.1 110053 D 405955 CDS YP_851297.1 117622384 4493080 110702..113407 1 NC_008563.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 113407 secA 4493080 secA Escherichia coli APEC O1 preprotein translocase subunit SecA YP_851297.1 110702 D 405955 CDS YP_851298.1 117622385 4493081 113467..113865 1 NC_008563.1 nucleoside triphosphate pyrophosphohydrolase 113865 mutT 4493081 mutT Escherichia coli APEC O1 nucleoside triphosphate pyrophosphohydrolase YP_851298.1 113467 D 405955 CDS YP_851299.1 117622386 4493082 complement(114160..114903) 1 NC_008563.1 hypothetical protein 114903 yacF 4493082 yacF Escherichia coli APEC O1 hypothetical protein YP_851299.1 114160 R 405955 CDS YP_851300.1 117622387 4493083 complement(114903..115523) 1 NC_008563.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 115523 coaE 4493083 coaE Escherichia coli APEC O1 dephospho-CoA kinase YP_851300.1 114903 R 405955 CDS YP_851301.1 117622388 4493084 115748..116791 1 NC_008563.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 116791 guaC 4493084 guaC Escherichia coli APEC O1 guanosine 5'-monophosphate oxidoreductase YP_851301.1 115748 D 405955 CDS YP_851302.1 117622389 4493085 complement(116826..118028) 1 NC_008563.1 type IV pilin biogenesis protein 118028 hofC 4493085 hofC Escherichia coli APEC O1 type IV pilin biogenesis protein YP_851302.1 116826 R 405955 CDS YP_851303.1 117622390 4492796 complement(118018..119403) 1 NC_008563.1 hypothetical protein 119403 hofB 4492796 hofB Escherichia coli APEC O1 hypothetical protein YP_851303.1 118018 R 405955 CDS YP_851304.1 117622391 4492797 complement(119413..119853) 1 NC_008563.1 major pilin subunit 119853 pppD 4492797 pppD Escherichia coli APEC O1 major pilin subunit YP_851304.1 119413 R 405955 CDS YP_851305.1 117622392 4492798 complement(120057..120992) 1 NC_008563.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 120992 nadC 4492798 nadC Escherichia coli APEC O1 quinolinate phosphoribosyltransferase YP_851305.1 120057 R 405955 CDS YP_851306.1 117622393 4492799 121038..121589 1 NC_008563.1 regulator of AmpC; N-acetyl-anhydromuranmyl-L-alanine amidase 121589 ampD 4492799 ampD Escherichia coli APEC O1 N-acetyl-anhydromuranmyl-L-alanine amidase YP_851306.1 121038 D 405955 CDS YP_851307.1 117622394 4492800 121586..122440 1 NC_008563.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 122440 ampE 4492800 ampE Escherichia coli APEC O1 regulatory protein AmpE YP_851307.1 121586 D 405955 CDS YP_851308.1 117622395 4492801 complement(122483..123853) 1 NC_008563.1 aromatic amino acid transporter 123853 aroP 4492801 aroP Escherichia coli APEC O1 aromatic amino acid transporter YP_851308.1 122483 R 405955 CDS YP_851309.1 117622396 4492802 124381..126162 1 NC_008563.1 similar to bacteriocin protein; uropathogenic specific protein 126162 usp 4492802 usp Escherichia coli APEC O1 uropathogenic specific protein YP_851309.1 124381 D 405955 CDS YP_851310.1 117622397 4492803 126165..126449 1 NC_008563.1 similar to colicin immunity protein; hypothetical protein 126449 4492803 APECO1_1875 Escherichia coli APEC O1 hypothetical protein YP_851310.1 126165 D 405955 CDS YP_851311.1 117622398 4492804 126857..127147 1 NC_008563.1 similar to colicin immunity protein; hypothetical protein 127147 4492804 APECO1_1874 Escherichia coli APEC O1 hypothetical protein YP_851311.1 126857 D 405955 CDS YP_851312.1 117622399 4492805 127550..127846 1 NC_008563.1 similar to colicin immunity protein; hypothetical protein 127846 4492805 APECO1_1873 Escherichia coli APEC O1 hypothetical protein YP_851312.1 127550 D 405955 CDS YP_851313.1 117622400 4492806 128302..129066 1 NC_008563.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 129066 pdhR 4492806 pdhR Escherichia coli APEC O1 transcriptional regulator PdhR YP_851313.1 128302 D 405955 CDS YP_851314.1 117622401 4492807 129227..131890 1 NC_008563.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 131890 aceE 4492807 aceE Escherichia coli APEC O1 pyruvate dehydrogenase subunit E1 YP_851314.1 129227 D 405955 CDS YP_851315.1 117622402 4492808 131905..133797 1 NC_008563.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 133797 aceF 4492808 aceF Escherichia coli APEC O1 dihydrolipoamide acetyltransferase YP_851315.1 131905 D 405955 CDS YP_851316.1 117622403 4492809 134001..135428 1 NC_008563.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 135428 lpd 4492809 lpd Escherichia coli APEC O1 dihydrolipoamide dehydrogenase YP_851316.1 134001 D 405955 CDS YP_851317.1 117622404 4492810 complement(135670..137427) 1 NC_008563.1 hypothetical protein 137427 yacH 4492810 yacH Escherichia coli APEC O1 hypothetical protein YP_851317.1 135670 R 405955 CDS YP_851318.1 117622405 4492811 137629..140379 1 NC_008563.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 140379 acnB 4492811 acnB Escherichia coli APEC O1 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_851318.1 137629 D 405955 CDS YP_851319.1 117622406 4492812 140506..140766 1 NC_008563.1 hypothetical protein 140766 yacL 4492812 yacL Escherichia coli APEC O1 hypothetical protein YP_851319.1 140506 D 405955 CDS YP_851320.1 117622407 4492813 complement(140950..141501) 1 NC_008563.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 141501 speD 4492813 speD Escherichia coli APEC O1 S-adenosylmethionine decarboxylase YP_851320.1 140950 R 405955 CDS YP_851321.1 117622408 4492814 complement(141760..142626) 1 NC_008563.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 142626 speE 4492814 speE Escherichia coli APEC O1 spermidine synthase YP_851321.1 141760 R 405955 CDS YP_851322.1 117622409 4492815 complement(142732..143118) 1 NC_008563.1 hypothetical protein 143118 yacC 4492815 yacC Escherichia coli APEC O1 hypothetical protein YP_851322.1 142732 R 405955 CDS YP_851323.1 117622410 4491696 143245..144795 1 NC_008563.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 144795 cueO 4491696 cueO Escherichia coli APEC O1 multicopper oxidase YP_851323.1 143245 D 405955 CDS YP_851324.1 117622411 4491697 complement(144842..147232) 1 NC_008563.1 glucose dehydrogenase 147232 gcd 4491697 gcd Escherichia coli APEC O1 glucose dehydrogenase YP_851324.1 144842 R 405955 CDS YP_851325.1 117622412 4491698 147399..147974 1 NC_008563.1 hypoxanthine-guanine phosphoribosyltransferase 147974 hpt 4491698 hpt Escherichia coli APEC O1 hypoxanthine-guanine phosphoribosyltransferase YP_851325.1 147399 D 405955 CDS YP_851326.1 117622413 4491699 complement(148015..148677) 1 NC_008563.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 148677 yadF 4491699 yadF Escherichia coli APEC O1 carbonic anhydrase YP_851326.1 148015 R 405955 CDS YP_851327.1 117622414 4491700 148786..149712 1 NC_008563.1 ABC transporter ATP-binding protein 149712 yadG 4491700 yadG Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_851327.1 148786 D 405955 CDS YP_851328.1 117622415 4491701 149709..150479 1 NC_008563.1 hypothetical protein 150479 4491701 APECO1_1857 Escherichia coli APEC O1 hypothetical protein YP_851328.1 149709 D 405955 CDS YP_851329.1 117622416 4491702 150584..151024 1 NC_008563.1 PTS system IIA component YadI 151024 yadI 4491702 yadI Escherichia coli APEC O1 PTS system IIA component YadI YP_851329.1 150584 D 405955 CDS YP_851330.1 117622417 4491703 151088..152317 1 NC_008563.1 hypothetical protein 152317 yadE 4491703 yadE Escherichia coli APEC O1 hypothetical protein YP_851330.1 151088 D 405955 CDS YP_851331.1 117622418 4491704 complement(152321..152701) 1 NC_008563.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 152701 4491704 APECO1_1854 Escherichia coli APEC O1 aspartate alpha-decarboxylase YP_851331.1 152321 R 405955 CDS YP_851332.1 117622419 4491705 152975..153859 1 NC_008563.1 hypothetical protein 153859 4491705 APECO1_1853 Escherichia coli APEC O1 hypothetical protein YP_851332.1 152975 D 405955 CDS YP_851333.1 117622420 4491706 complement(153941..154792) 1 NC_008563.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 154792 panC 4491706 panC Escherichia coli APEC O1 pantoate--beta-alanine ligase YP_851333.1 153941 R 405955 CDS YP_851334.1 117622421 4491707 complement(154804..155598) 1 NC_008563.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 155598 panB 4491707 panB Escherichia coli APEC O1 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_851334.1 154804 R 405955 CDS YP_851335.1 117622422 4491708 complement(155710..156975) 1 NC_008563.1 fimbrial-like adhesin protein 156975 yadC 4491708 yadC Escherichia coli APEC O1 fimbrial-like adhesin protein YP_851335.1 155710 R 405955 CDS YP_851336.1 117622423 4491709 complement(157025..157621) 1 NC_008563.1 hypothetical protein 157621 yadK 4491709 yadK Escherichia coli APEC O1 hypothetical protein YP_851336.1 157025 R 405955 CDS YP_851337.1 117622424 4491710 complement(157648..158262) 1 NC_008563.1 hypothetical protein 158262 yadL 4491710 yadL Escherichia coli APEC O1 hypothetical protein YP_851337.1 157648 R 405955 CDS YP_851338.1 117622425 4491711 complement(158268..158834) 1 NC_008563.1 fimbrial-like adhesin protein 158834 yadM 4491711 yadM Escherichia coli APEC O1 fimbrial-like adhesin protein YP_851338.1 158268 R 405955 CDS YP_851339.1 117622426 4491712 complement(158851..161439) 1 NC_008563.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 161439 htrE 4491712 htrE Escherichia coli APEC O1 outer membrane usher protein YP_851339.1 158851 R 405955 CDS YP_851340.1 117622427 4491713 complement(161474..162214) 1 NC_008563.1 chaperone protein EcpD 162214 ecpD 4491713 ecpD Escherichia coli APEC O1 chaperone protein EcpD YP_851340.1 161474 R 405955 CDS YP_851341.1 117622428 4491714 complement(162323..162937) 1 NC_008563.1 fimbrial-like adhesin protein 162937 yadN 4491714 yadN Escherichia coli APEC O1 fimbrial-like adhesin protein YP_851341.1 162323 R 405955 CDS YP_851342.1 117622429 4495464 complement(163275..163754) 1 NC_008563.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 163754 folK 4495464 folK Escherichia coli APEC O1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_851342.1 163275 R 405955 CDS YP_851343.1 117622430 4495465 complement(163751..165115) 1 NC_008563.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 165115 pcnB 4495465 pcnB Escherichia coli APEC O1 poly(A) polymerase I YP_851343.1 163751 R 405955 CDS YP_851344.2 162317587 4495466 complement(165208..166104) 1 NC_008563.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 166104 yadB 4495466 yadB Escherichia coli APEC O1 glutamyl-Q tRNA(Asp) synthetase YP_851344.2 165208 R 405955 CDS YP_851345.1 117622432 4495467 complement(166171..166644) 1 NC_008563.1 RNA polymerase-binding transcription factor 166644 dksA 4495467 dksA Escherichia coli APEC O1 RNA polymerase-binding transcription factor YP_851345.1 166171 R 405955 CDS YP_851346.1 117622433 4495468 complement(166804..167508) 1 NC_008563.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 167508 4495468 APECO1_1839 Escherichia coli APEC O1 sugar fermentation stimulation protein A YP_851346.1 166804 R 405955 CDS YP_851347.1 117622434 4495469 complement(167523..168266) 1 NC_008563.1 2'-5' RNA ligase 168266 yadP 4495469 yadP Escherichia coli APEC O1 2'-5' RNA ligase YP_851347.1 167523 R 405955 CDS YP_851348.1 117622435 4495470 168082..170556 1 NC_008563.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 170556 hrpB 4495470 hrpB Escherichia coli APEC O1 ATP-dependent RNA helicase HrpB YP_851348.1 168082 D 405955 CDS YP_851349.1 117622436 4495472 170650..173184 1 NC_008563.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 173184 mrcB 4495472 mrcB Escherichia coli APEC O1 penicillin-binding protein 1b YP_851349.1 170650 D 405955 CDS YP_851350.1 117622437 4495473 173404..175647 1 NC_008563.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 175647 fhuA 4495473 fhuA Escherichia coli APEC O1 ferrichrome outer membrane transporter YP_851350.1 173404 D 405955 CDS YP_851351.1 117622438 4495474 175698..176495 1 NC_008563.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 176495 fhuC 4495474 fhuC Escherichia coli APEC O1 iron-hydroxamate transporter ATP-binding subunit YP_851351.1 175698 D 405955 CDS YP_851352.1 117622439 4495475 176495..177385 1 NC_008563.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 177385 fhuD 4495475 fhuD Escherichia coli APEC O1 iron-hydroxamate transporter substrate-binding subunit YP_851352.1 176495 D 405955 CDS YP_851353.1 117622440 4495476 177382..179364 1 NC_008563.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 179364 fhuB 4495476 fhuB Escherichia coli APEC O1 iron-hydroxamate transporter permease subunit YP_851353.1 177382 D 405955 CDS YP_851354.1 117622441 4495477 complement(179399..180679) 1 NC_008563.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 180679 hemL 4495477 hemL Escherichia coli APEC O1 glutamate-1-semialdehyde aminotransferase YP_851354.1 179399 R 405955 CDS YP_851355.1 117622442 4495478 180904..182325 1 NC_008563.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 182325 yadQ 4495478 yadQ Escherichia coli APEC O1 chloride channel protein YP_851355.1 180904 D 405955 CDS YP_851356.1 117622443 4495479 182407..182751 1 NC_008563.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 182751 yadR 4495479 yadR Escherichia coli APEC O1 iron-sulfur cluster insertion protein ErpA YP_851356.1 182407 D 405955 CDS YP_851357.1 117622444 4495480 complement(182798..183421) 1 NC_008563.1 hypothetical protein 183421 yadS 4495480 yadS Escherichia coli APEC O1 hypothetical protein YP_851357.1 182798 R 405955 CDS YP_851358.1 117622445 4495481 complement(183459..184259) 1 NC_008563.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 184259 yadT 4495481 yadT Escherichia coli APEC O1 vitamin B12-transporter protein BtuF YP_851358.1 183459 R 405955 CDS YP_851359.1 117622446 4495482 complement(184252..184950) 1 NC_008563.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 184950 4495482 APECO1_1826 Escherichia coli APEC O1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_851359.1 184252 R 405955 CDS YP_851360.1 117622447 4495483 185034..186551 1 NC_008563.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 186551 dgt 4495483 dgt Escherichia coli APEC O1 deoxyguanosinetriphosphate triphosphohydrolase YP_851360.1 185034 D 405955 CDS YP_851361.1 117622448 4493684 186681..188105 1 NC_008563.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 188105 htrA 4493684 htrA Escherichia coli APEC O1 serine endoprotease YP_851361.1 186681 D 405955 CDS YP_851362.1 117622449 4493685 188283..189413 1 NC_008563.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 189413 cdaR 4493685 cdaR Escherichia coli APEC O1 carbohydrate diacid transcriptional activator CdaR YP_851362.1 188283 D 405955 CDS YP_851363.1 117622450 4493686 complement(189467..189853) 1 NC_008563.1 hypothetical protein 189853 4493686 APECO1_1822 Escherichia coli APEC O1 hypothetical protein YP_851363.1 189467 R 405955 CDS YP_851364.1 117622451 4493687 complement(190165..190989) 1 NC_008563.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 190989 dapD 4493687 dapD Escherichia coli APEC O1 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_851364.1 190165 R 405955 CDS YP_851365.1 117622452 4493688 complement(191020..193692) 1 NC_008563.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 193692 glnD 4493688 glnD Escherichia coli APEC O1 PII uridylyl-transferase YP_851365.1 191020 R 405955 CDS YP_851366.1 117622453 4493689 complement(193754..194548) 1 NC_008563.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 194548 map 4493689 map Escherichia coli APEC O1 methionine aminopeptidase YP_851366.1 193754 R 405955 CDS YP_851367.1 117622454 4493690 194916..195641 1 NC_008563.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 195641 rpsB 4493690 rpsB Escherichia coli APEC O1 30S ribosomal protein S2 YP_851367.1 194916 D 405955 CDS YP_851368.1 117622455 4493691 complement(195593..196522) 1 NC_008563.1 hypothetical protein 196522 4493691 APECO1_1817 Escherichia coli APEC O1 hypothetical protein YP_851368.1 195593 R 405955 CDS YP_851369.1 117622456 4493692 196774..197499 1 NC_008563.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 197499 pyrH 4493692 pyrH Escherichia coli APEC O1 uridylate kinase YP_851369.1 196774 D 405955 CDS YP_851370.1 117622457 4493693 197685..198206 1 NC_008563.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 198206 frr 4493693 frr Escherichia coli APEC O1 ribosome recycling factor YP_851370.1 197685 D 405955 CDS YP_851371.1 117622458 4493694 198298..199494 1 NC_008563.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 199494 dxr 4493694 dxr Escherichia coli APEC O1 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_851371.1 198298 D 405955 CDS YP_851372.1 117622459 4493695 199680..200441 1 NC_008563.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 200441 4493695 APECO1_1813 Escherichia coli APEC O1 undecaprenyl pyrophosphate synthase YP_851372.1 199680 D 405955 CDS YP_851373.1 117622460 4493696 200484..201311 1 NC_008563.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 201311 cdsA 4493696 cdsA Escherichia coli APEC O1 CDP-diglyceride synthase YP_851373.1 200484 D 405955 CDS YP_851374.1 117622461 4493697 201323..202675 1 NC_008563.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 202675 yaeL 4493697 yaeL Escherichia coli APEC O1 zinc metallopeptidase RseP YP_851374.1 201323 D 405955 CDS YP_851375.1 117622462 4493698 202705..205137 1 NC_008563.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 205137 4493698 APECO1_1810 Escherichia coli APEC O1 outer membrane protein assembly factor YaeT YP_851375.1 202705 D 405955 CDS YP_851376.1 117622463 4493699 205259..205744 1 NC_008563.1 periplasmic chaperone 205744 4493699 APECO1_1809 Escherichia coli APEC O1 periplasmic chaperone YP_851376.1 205259 D 405955 CDS YP_851377.1 117622464 4493700 205748..206773 1 NC_008563.1 third step of endotoxin (lipidA) synthesis; adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 206773 lpxD 4493700 lpxD Escherichia coli APEC O1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_851377.1 205748 D 405955 CDS YP_851378.1 117622465 4493701 206953..207333 1 NC_008563.1 (3R)-hydroxymyristoyl-ACP dehydratase 207333 fabZ 4493701 fabZ Escherichia coli APEC O1 (3R)-hydroxymyristoyl-ACP dehydratase YP_851378.1 206953 D 405955 CDS YP_851379.1 117622466 4493702 207337..208125 1 NC_008563.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 208125 lpxA 4493702 lpxA Escherichia coli APEC O1 UDP-N-acetylglucosamine acyltransferase YP_851379.1 207337 D 405955 CDS YP_851380.1 117622467 4494815 208125..209273 1 NC_008563.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 209273 lpxB 4494815 lpxB Escherichia coli APEC O1 lipid-A-disaccharide synthase YP_851380.1 208125 D 405955 CDS YP_851381.1 117622468 4494816 209270..209866 1 NC_008563.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 209866 rnhB 4494816 rnhB Escherichia coli APEC O1 ribonuclease HII YP_851381.1 209270 D 405955 CDS YP_851382.1 117622469 4494817 209903..213385 1 NC_008563.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 213385 dnaE 4494817 dnaE Escherichia coli APEC O1 DNA polymerase III subunit alpha YP_851382.1 209903 D 405955 CDS YP_851383.1 117622470 4494818 213398..214357 1 NC_008563.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 214357 accA 4494818 accA Escherichia coli APEC O1 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_851383.1 213398 D 405955 CDS YP_851384.1 117622471 4494819 214455..216596 1 NC_008563.1 lysine decarboxylase, constitutive 216596 ldcC 4494819 ldcC Escherichia coli APEC O1 lysine decarboxylase, constitutive YP_851384.1 214455 D 405955 CDS YP_851385.1 117622472 4494820 216626..217042 1 NC_008563.1 hypothetical protein 217042 yaeR 4494820 yaeR Escherichia coli APEC O1 hypothetical protein YP_851385.1 216626 D 405955 CDS YP_851386.1 117622473 4494821 217107..218405 1 NC_008563.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 218405 tilS 4494821 tilS Escherichia coli APEC O1 tRNA(Ile)-lysidine synthetase YP_851386.1 217107 D 405955 CDS YP_851387.1 117622474 4494822 complement(218453..218713) 1 NC_008563.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 218713 rof 4494822 rof Escherichia coli APEC O1 Rho-binding antiterminator YP_851387.1 218453 R 405955 CDS YP_851388.1 117622475 4494823 219066..219611 1 NC_008563.1 hypothetical protein 219611 yaeQ 4494823 yaeQ Escherichia coli APEC O1 hypothetical protein YP_851388.1 219066 D 405955 CDS YP_851389.1 117622476 4494824 219608..220030 1 NC_008563.1 peptidyl-tRNA hydrolase domain-containing protein 220030 yaeJ 4494824 yaeJ Escherichia coli APEC O1 peptidyl-tRNA hydrolase domain-containing protein YP_851389.1 219608 D 405955 CDS YP_851390.1 117622477 4494825 220044..220754 1 NC_008563.1 lipoprotein involved with copper homeostasis and adhesion 220754 cutF 4494825 cutF Escherichia coli APEC O1 lipoprotein involved with copper homeostasis and adhesion YP_851390.1 220044 D 405955 CDS YP_851391.1 117622478 4494826 complement(220910..221734) 1 NC_008563.1 hypothetical protein 221734 yaeF 4494826 yaeF Escherichia coli APEC O1 hypothetical protein YP_851391.1 220910 R 405955 CDS YP_851392.1 117622479 4494827 complement(221787..223505) 1 NC_008563.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 223505 proS 4494827 proS Escherichia coli APEC O1 prolyl-tRNA synthetase YP_851392.1 221787 R 405955 CDS YP_851393.1 117622480 4494828 complement(223616..224323) 1 NC_008563.1 hypothetical protein 224323 yaeB 4494828 yaeB Escherichia coli APEC O1 hypothetical protein YP_851393.1 223616 R 405955 CDS YP_851394.1 117622481 4494829 complement(224320..224724) 1 NC_008563.1 outer membrane lipoprotein 224724 rcsF 4494829 rcsF Escherichia coli APEC O1 outer membrane lipoprotein YP_851394.1 224320 R 405955 CDS YP_851395.1 117622482 4494830 complement(224842..225657) 1 NC_008563.1 DL-methionine transporter substrate-binding subunit 225657 metQ 4494830 metQ Escherichia coli APEC O1 DL-methionine transporter substrate-binding subunit YP_851395.1 224842 R 405955 CDS YP_851396.1 117622483 4494831 complement(225697..226350) 1 NC_008563.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 226350 metI 4494831 metI Escherichia coli APEC O1 DL-methionine transporter permease YP_851396.1 225697 R 405955 CDS YP_851397.1 117622484 4494832 complement(226343..227374) 1 NC_008563.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 227374 metN 4494832 metN Escherichia coli APEC O1 DL-methionine transporter ATP-binding subunit YP_851397.1 226343 R 405955 CDS YP_851398.1 117622485 4494833 227562..228134 1 NC_008563.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 228134 yaeD 4494833 yaeD Escherichia coli APEC O1 D,D-heptose 1,7-bisphosphate phosphatase YP_851398.1 227562 D 405955 CDS YP_851402.1 117622489 4495809 233893..234696 1 NC_008563.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 234696 dkgB 4495809 dkgB Escherichia coli APEC O1 2,5-diketo-D-gluconate reductase B YP_851402.1 233893 D 405955 CDS YP_851403.1 117622490 4495810 complement(234693..235607) 1 NC_008563.1 LysR family transcriptional regulator 235607 4495810 APECO1_1782 Escherichia coli APEC O1 LysR family transcriptional regulator YP_851403.1 234693 R 405955 CDS YP_851404.1 117622491 4495811 235824..236648 1 NC_008563.1 hypothetical protein 236648 yafD 4495811 yafD Escherichia coli APEC O1 hypothetical protein YP_851404.1 235824 D 405955 CDS YP_851405.1 117622492 4495812 236726..237496 1 NC_008563.1 hypothetical protein 237496 yafE 4495812 yafE Escherichia coli APEC O1 hypothetical protein YP_851405.1 236726 D 405955 CDS YP_851406.1 117622493 4495813 complement(237543..238901) 1 NC_008563.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 238901 mltD 4495813 mltD Escherichia coli APEC O1 membrane-bound lytic murein transglycosylase D YP_851406.1 237543 R 405955 CDS YP_851407.1 117622494 4495814 complement(238973..239728) 1 NC_008563.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 239728 gloB 4495814 gloB Escherichia coli APEC O1 hydroxyacylglutathione hydrolase YP_851407.1 238973 R 405955 CDS YP_851408.1 117622495 4495815 239744..240484 1 NC_008563.1 S-adenosyl-L-methionine-dependent methyltransferase 240484 yafS 4495815 yafS Escherichia coli APEC O1 S-adenosyl-L-methionine-dependent methyltransferase YP_851408.1 239744 D 405955 CDS YP_851409.1 117622496 4495816 complement(240481..241059) 1 NC_008563.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 241059 rnhA 4495816 rnhA Escherichia coli APEC O1 ribonuclease H YP_851409.1 240481 R 405955 CDS YP_851410.1 117622497 4495817 241004..241744 1 NC_008563.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 241744 dnaQ 4495817 dnaQ Escherichia coli APEC O1 DNA polymerase III subunit epsilon YP_851410.1 241004 D 405955 CDS YP_851412.1 117622499 4495819 242282..243067 1 NC_008563.1 aminopeptidase 243067 yafT 4495819 yafT Escherichia coli APEC O1 aminopeptidase YP_851412.1 242282 D 405955 CDS YP_851413.1 117622500 4495820 complement(243407..243886) 1 NC_008563.1 similar to hemolysin co-regulated protein; hypothetical protein 243886 aec32 4495820 aec32 Escherichia coli APEC O1 hypothetical protein YP_851413.1 243407 R 405955 CDS YP_851414.1 117622501 4495821 complement(243904..245403) 1 NC_008563.1 hypothetical protein 245403 aec31 4495821 aec31 Escherichia coli APEC O1 hypothetical protein YP_851414.1 243904 R 405955 CDS YP_851415.1 117622502 4495822 complement(245273..248800) 1 NC_008563.1 similar to macrophage toxin; hypothetical protein 248800 aec30 4495822 aec30 Escherichia coli APEC O1 hypothetical protein YP_851415.1 245273 R 405955 CDS YP_851416.1 117622503 4495823 complement(248820..250262) 1 NC_008563.1 hypothetical protein 250262 aec29 4495823 aec29 Escherichia coli APEC O1 hypothetical protein YP_851416.1 248820 R 405955 CDS YP_851417.1 117622504 4495824 complement(250267..251010) 1 NC_008563.1 hypothetical protein 251010 aec28 4495824 aec28 Escherichia coli APEC O1 hypothetical protein YP_851417.1 250267 R 405955 CDS YP_851418.1 117622505 4495825 complement(251007..253766) 1 NC_008563.1 ATPase 253766 aec27 4495825 aec27 Escherichia coli APEC O1 ATPase YP_851418.1 251007 R 405955 CDS YP_851419.1 117622506 4495095 complement(253776..254540) 1 NC_008563.1 hypothetical protein 254540 aec26 4495095 aec26 Escherichia coli APEC O1 hypothetical protein YP_851419.1 253776 R 405955 CDS YP_851420.1 117622507 4495096 complement(254545..255891) 1 NC_008563.1 hypothetical protein 255891 aec25 4495096 aec25 Escherichia coli APEC O1 hypothetical protein YP_851420.1 254545 R 405955 CDS YP_851421.1 117622508 4495097 complement(255894..256418) 1 NC_008563.1 hypothetical protein 256418 aec24 4495097 aec24 Escherichia coli APEC O1 hypothetical protein YP_851421.1 255894 R 405955 CDS YP_851422.1 117622509 4495098 complement(256415..257707) 1 NC_008563.1 hypothetical protein 257707 aec23 4495098 aec23 Escherichia coli APEC O1 hypothetical protein YP_851422.1 256415 R 405955 CDS YP_851423.1 117622510 4495099 complement(257712..258761) 1 NC_008563.1 hypothetical protein 258761 aec22 4495099 aec22 Escherichia coli APEC O1 hypothetical protein YP_851423.1 257712 R 405955 CDS YP_851424.1 117622511 4495100 complement(258725..260575) 1 NC_008563.1 hypothetical protein 260575 4495100 APECO1_1761 Escherichia coli APEC O1 hypothetical protein YP_851424.1 258725 R 405955 CDS YP_851425.1 117622512 4495101 complement(260572..260997) 1 NC_008563.1 hypothetical protein 260997 aec19 4495101 aec19 Escherichia coli APEC O1 hypothetical protein YP_851425.1 260572 R 405955 CDS YP_851426.1 117622513 4495102 complement(261002..262486) 1 NC_008563.1 hypothetical protein 262486 aec18 4495102 aec18 Escherichia coli APEC O1 hypothetical protein YP_851426.1 261002 R 405955 CDS YP_851427.1 117622514 4495103 complement(262509..263012) 1 NC_008563.1 hypothetical protein 263012 aec17 4495103 aec17 Escherichia coli APEC O1 hypothetical protein YP_851427.1 262509 R 405955 CDS YP_851428.1 117622515 4495104 263718..264236 1 NC_008563.1 hypothetical protein 264236 aec16 4495104 aec16 Escherichia coli APEC O1 hypothetical protein YP_851428.1 263718 D 405955 CDS YP_851429.1 117622516 4495105 264457..266439 1 NC_008563.1 hypothetical protein 266439 aec15 4495105 aec15 Escherichia coli APEC O1 hypothetical protein YP_851429.1 264457 D 405955 CDS YP_851430.1 117622517 4495106 266546..267592 1 NC_008563.1 hypothetical protein 267592 aec14 4495106 aec14 Escherichia coli APEC O1 hypothetical protein YP_851430.1 266546 D 405955 CDS YP_851431.1 117622518 4495107 267585..269024 1 NC_008563.1 hypothetical protein 269024 4495107 APECO1_1753 Escherichia coli APEC O1 hypothetical protein YP_851431.1 267585 D 405955 CDS YP_851432.1 117622519 4495108 268999..269289 1 NC_008563.1 hypothetical protein 269289 aec11 4495108 aec11 Escherichia coli APEC O1 hypothetical protein YP_851432.1 268999 D 405955 CDS YP_851433.1 117622520 4495109 269826..270311 1 NC_008563.1 transposase 270311 yhhI 4495109 yhhI Escherichia coli APEC O1 transposase YP_851433.1 269826 D 405955 CDS YP_851434.1 117622521 4495110 270540..271043 1 NC_008563.1 hypothetical protein 271043 aec8 4495110 aec8 Escherichia coli APEC O1 hypothetical protein YP_851434.1 270540 D 405955 CDS YP_851435.1 117622522 4495111 271113..271625 1 NC_008563.1 hypothetical protein 271625 aec7 4495111 aec7 Escherichia coli APEC O1 hypothetical protein YP_851435.1 271113 D 405955 CDS YP_851436.1 117622523 4495112 complement(271896..272666) 1 NC_008563.1 hypothetical protein 272666 yafV 4495112 yafV Escherichia coli APEC O1 hypothetical protein YP_851436.1 271896 R 405955 CDS YP_851437.1 117622524 4495113 272820..273293 1 NC_008563.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 273293 ivy 4495113 ivy Escherichia coli APEC O1 C-lysozyme inhibitor YP_851437.1 272820 D 405955 CDS YP_851438.2 162317586 4495114 complement(273336..275780) 1 NC_008563.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 275780 fadE 4495114 fadE Escherichia coli APEC O1 acyl-CoA dehydrogenase YP_851438.2 273336 R 405955 CDS YP_851439.1 117622526 4495049 275858..276598 1 NC_008563.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 276598 gmhA 4495049 gmhA Escherichia coli APEC O1 phosphoheptose isomerase YP_851439.1 275858 D 405955 CDS YP_851440.1 117622527 4495050 276804..277571 1 NC_008563.1 amidotransferase 277571 yafJ 4495050 yafJ Escherichia coli APEC O1 amidotransferase YP_851440.1 276804 D 405955 CDS YP_851441.1 117622528 4495051 complement(277542..278282) 1 NC_008563.1 hypothetical protein 278282 yafK 4495051 yafK Escherichia coli APEC O1 hypothetical protein YP_851441.1 277542 R 405955 CDS YP_851442.1 117622529 4495052 278585..279343 1 NC_008563.1 lipoprotein 279343 yafL 4495052 yafL Escherichia coli APEC O1 lipoprotein YP_851442.1 278585 D 405955 CDS YP_851443.1 117622530 4495053 279519..280016 1 NC_008563.1 hypothetical protein 280016 yafM 4495053 yafM Escherichia coli APEC O1 hypothetical protein YP_851443.1 279519 D 405955 CDS YP_851444.1 117622531 4495054 complement(280336..282075) 1 NC_008563.1 FhiA protein 282075 fhiA 4495054 fhiA Escherichia coli APEC O1 FhiA protein YP_851444.1 280336 R 405955 CDS YP_851445.1 117622532 4495057 282020..282805 1 NC_008563.1 hypothetical protein 282805 mbhA 4495057 mbhA Escherichia coli APEC O1 hypothetical protein YP_851445.1 282020 D 405955 CDS YP_851446.1 117622533 4495059 282876..283931 1 NC_008563.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 283931 dinB 4495059 dinB Escherichia coli APEC O1 DNA polymerase IV YP_851446.1 282876 D 405955 CDS YP_851447.1 117622534 4495060 283983..284276 1 NC_008563.1 antitoxin of the YafO-YafN toxin-antitoxin system 284276 yafN 4495060 yafN Escherichia coli APEC O1 antitoxin of the YafO-YafN toxin-antitoxin system YP_851447.1 283983 D 405955 CDS YP_851448.1 117622535 4495061 284279..284677 1 NC_008563.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 284677 4495061 APECO1_1736 Escherichia coli APEC O1 toxin YafO YP_851448.1 284279 D 405955 CDS YP_851449.1 117622536 4495062 284687..285139 1 NC_008563.1 hypothetical protein 285139 yafP 4495062 yafP Escherichia coli APEC O1 hypothetical protein YP_851449.1 284687 D 405955 CDS YP_851450.1 117622537 4495063 285317..286468 1 NC_008563.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 286468 4495063 APECO1_1734 Escherichia coli APEC O1 hypothetical protein YP_851450.1 285317 D 405955 CDS YP_851451.1 117622538 4495064 286381..287079 1 NC_008563.1 similar to release factor 1 and 2; peptide chain release factor-like protein 287079 prfH 4495064 prfH Escherichia coli APEC O1 peptide chain release factor-like protein YP_851451.1 286381 D 405955 CDS YP_851452.1 117622539 4495065 complement(287136..288593) 1 NC_008563.1 aminoacyl-histidine dipeptidase 288593 pepD 4495065 pepD Escherichia coli APEC O1 aminoacyl-histidine dipeptidase YP_851452.1 287136 R 405955 CDS YP_851453.1 117622540 4495066 288854..289312 1 NC_008563.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 289312 gpt 4495066 gpt Escherichia coli APEC O1 xanthine-guanine phosphoribosyltransferase YP_851453.1 288854 D 405955 CDS YP_851454.1 117622541 4495067 289404..290648 1 NC_008563.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 290648 frsA 4495067 frsA Escherichia coli APEC O1 fermentation/respiration switch protein YP_851454.1 289404 D 405955 CDS YP_851455.1 117622542 4492718 290706..291107 1 NC_008563.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 291107 crl 4492718 crl Escherichia coli APEC O1 DNA-binding transcriptional regulator Crl YP_851455.1 290706 D 405955 CDS YP_851456.1 117622543 4492719 complement(291217..292278) 1 NC_008563.1 outer membrane phosphoporin protein E 292278 phoE 4492719 phoE Escherichia coli APEC O1 outer membrane phosphoporin protein E YP_851456.1 291217 R 405955 CDS YP_851457.1 117622544 4492720 292561..293664 1 NC_008563.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 293664 proB 4492720 proB Escherichia coli APEC O1 gamma-glutamyl kinase YP_851457.1 292561 D 405955 CDS YP_851458.1 117622545 4492721 293676..294929 1 NC_008563.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 294929 proA 4492721 proA Escherichia coli APEC O1 gamma-glutamyl phosphate reductase YP_851458.1 293676 D 405955 CDS YP_851459.1 117622546 4492722 complement(295178..295492) 1 NC_008563.1 hypothetical protein 295492 4492722 APECO1_1725 Escherichia coli APEC O1 hypothetical protein YP_851459.1 295178 R 405955 CDS YP_851460.1 117622547 4492723 296225..296608 1 NC_008563.1 hypothetical protein 296608 4492723 APECO1_1724 Escherichia coli APEC O1 hypothetical protein YP_851460.1 296225 D 405955 CDS YP_851461.1 117622548 4492724 299152..299841 1 NC_008563.1 hypothetical protein 299841 4492724 APECO1_1723 Escherichia coli APEC O1 hypothetical protein YP_851461.1 299152 D 405955 CDS YP_851462.1 117622549 4492725 299853..300131 1 NC_008563.1 hypothetical protein 300131 4492725 APECO1_1722 Escherichia coli APEC O1 hypothetical protein YP_851462.1 299853 D 405955 CDS YP_851463.1 117622550 4492726 300264..300668 1 NC_008563.1 hypothetical protein 300668 4492726 APECO1_1721 Escherichia coli APEC O1 hypothetical protein YP_851463.1 300264 D 405955 CDS YP_851464.1 117622551 4492727 300646..301005 1 NC_008563.1 hypothetical protein 301005 4492727 APECO1_1720 Escherichia coli APEC O1 hypothetical protein YP_851464.1 300646 D 405955 CDS YP_851465.1 117622552 4492728 301550..301912 1 NC_008563.1 hypothetical protein 301912 4492728 APECO1_1719 Escherichia coli APEC O1 hypothetical protein YP_851465.1 301550 D 405955 CDS YP_851466.1 117622553 4492729 301931..302959 1 NC_008563.1 hypothetical protein 302959 4492729 APECO1_1718 Escherichia coli APEC O1 hypothetical protein YP_851466.1 301931 D 405955 CDS YP_851467.1 117622554 4492730 303266..305095 1 NC_008563.1 hypothetical protein 305095 4492730 APECO1_1717 Escherichia coli APEC O1 hypothetical protein YP_851467.1 303266 D 405955 CDS YP_851468.1 117622555 4492731 305130..305843 1 NC_008563.1 hypothetical protein 305843 4492731 APECO1_1716 Escherichia coli APEC O1 hypothetical protein YP_851468.1 305130 D 405955 CDS YP_851469.1 117622556 4492732 complement(305925..307259) 1 NC_008563.1 integrase 307259 4492732 APECO1_1715 Escherichia coli APEC O1 integrase YP_851469.1 305925 R 405955 CDS YP_851470.1 117622557 4492733 complement(307569..307961) 1 NC_008563.1 integrase 307961 4492733 APECO1_1714 Escherichia coli APEC O1 integrase YP_851470.1 307569 R 405955 CDS YP_851471.1 117622558 4492734 complement(308292..308816) 1 NC_008563.1 hypothetical protein 308816 4492734 APECO1_1713 Escherichia coli APEC O1 hypothetical protein YP_851471.1 308292 R 405955 CDS YP_851472.1 117622559 4492735 complement(308942..313072) 1 NC_008563.1 hemoglobin protease; vacuolating autotransporter 313072 vat 4492735 vat Escherichia coli APEC O1 vacuolating autotransporter YP_851472.1 308942 R 405955 CDS YP_851473.1 117622560 4492737 complement(314071..314346) 1 NC_008563.1 hypothetical protein 314346 4492737 APECO1_1711 Escherichia coli APEC O1 hypothetical protein YP_851473.1 314071 R 405955 CDS YP_851474.1 117622561 4494875 315182..315796 1 NC_008563.1 hypothetical protein 315796 yagU 4494875 yagU Escherichia coli APEC O1 hypothetical protein YP_851474.1 315182 D 405955 CDS YP_851475.1 117622562 4494876 complement(316045..316374) 1 NC_008563.1 ferredoxin 316374 ykgJ 4494876 ykgJ Escherichia coli APEC O1 ferredoxin YP_851475.1 316045 R 405955 CDS YP_851476.1 117622563 4494877 complement(316681..317436) 1 NC_008563.1 hypothetical protein 317436 yagV 4494877 yagV Escherichia coli APEC O1 hypothetical protein YP_851476.1 316681 R 405955 CDS YP_851477.1 117622564 4494878 complement(317360..319003) 1 NC_008563.1 hypothetical protein 319003 yagW 4494878 yagW Escherichia coli APEC O1 hypothetical protein YP_851477.1 317360 R 405955 CDS YP_851478.1 117622565 4494879 complement(318993..321518) 1 NC_008563.1 hypothetical protein 321518 yagX 4494879 yagX Escherichia coli APEC O1 hypothetical protein YP_851478.1 318993 R 405955 CDS YP_851479.1 117622566 4494880 complement(321544..322260) 1 NC_008563.1 hypothetical protein 322260 yagY 4494880 yagY Escherichia coli APEC O1 hypothetical protein YP_851479.1 321544 R 405955 CDS YP_851480.1 117622567 4494881 complement(322269..322856) 1 NC_008563.1 hypothetical protein 322856 matB 4494881 matB Escherichia coli APEC O1 hypothetical protein YP_851480.1 322269 R 405955 CDS YP_851481.1 117622568 4494882 complement(322930..323520) 1 NC_008563.1 hypothetical protein 323520 ykgK 4494882 ykgK Escherichia coli APEC O1 hypothetical protein YP_851481.1 322930 R 405955 CDS YP_851482.1 117622569 4494883 323944..324234 1 NC_008563.1 hypothetical protein 324234 4494883 APECO1_1702 Escherichia coli APEC O1 hypothetical protein YP_851482.1 323944 D 405955 CDS YP_851483.1 117622570 4494884 complement(324696..324962) 1 NC_008563.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 324962 rpmE2 4494884 rpmE2 Escherichia coli APEC O1 50S ribosomal protein L31 YP_851483.1 324696 R 405955 CDS YP_851484.1 117622571 4494885 complement(325899..327041) 1 NC_008563.1 NADH-dependent flavin oxidoreductase 327041 4494885 APECO1_1700 Escherichia coli APEC O1 NADH-dependent flavin oxidoreductase YP_851484.1 325899 R 405955 CDS YP_851485.1 117622572 4494886 complement(327213..328133) 1 NC_008563.1 hypothetical protein 328133 ycjY 4494886 ycjY Escherichia coli APEC O1 hypothetical protein YP_851485.1 327213 R 405955 CDS YP_851486.1 117622573 4494887 328227..329216 1 NC_008563.1 LysR family transcriptional regulator 329216 4494887 APECO1_1698 Escherichia coli APEC O1 LysR family transcriptional regulator YP_851486.1 328227 D 405955 CDS YP_851487.1 117622574 4494888 329341..330309 1 NC_008563.1 transcriptional regulator 330309 ycjZ 4494888 ycjZ Escherichia coli APEC O1 transcriptional regulator YP_851487.1 329341 D 405955 CDS YP_851488.1 117622575 4494889 complement(330340..331329) 1 NC_008563.1 aldo/keto reductase 331329 4494889 APECO1_1696 Escherichia coli APEC O1 aldo/keto reductase YP_851488.1 330340 R 405955 CDS YP_851489.1 117622576 4494890 complement(331356..332207) 1 NC_008563.1 2,5-diketo-D-gluconic acid reductase A 332207 4494890 APECO1_1695 Escherichia coli APEC O1 2,5-diketo-D-gluconic acid reductase A YP_851489.1 331356 R 405955 CDS YP_851490.1 117622577 4494891 332773..337023 1 NC_008563.1 attaching and effacing protein, pathogenesis factor EaeH 337023 eaeH 4494891 eaeH Escherichia coli APEC O1 attaching and effacing protein, pathogenesis factor EaeH YP_851490.1 332773 D 405955 CDS YP_851491.1 117622578 4494892 complement(337148..338038) 1 NC_008563.1 transcriptional regulator 338038 ykgA 4494892 ykgA Escherichia coli APEC O1 transcriptional regulator YP_851491.1 337148 R 405955 CDS YP_851492.1 117622579 4494893 338238..339122 1 NC_008563.1 2,5-diketo-D-gluconic acid reductase A 339122 4494893 APECO1_1692 Escherichia coli APEC O1 2,5-diketo-D-gluconic acid reductase A YP_851492.1 338238 D 405955 CDS YP_851493.1 117622580 4495503 complement(339282..339884) 1 NC_008563.1 hypothetical protein 339884 ykgB 4495503 ykgB Escherichia coli APEC O1 hypothetical protein YP_851493.1 339282 R 405955 CDS YP_851494.1 117622581 4495504 complement(340232..341584) 1 NC_008563.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 341584 ykgC 4495504 ykgC Escherichia coli APEC O1 pyridine nucleotide-disulfide oxidoreductase YP_851494.1 340232 R 405955 CDS YP_851495.1 117622582 4495505 341784..342638 1 NC_008563.1 DNA-binding transcriptional regulator 342638 ykgD 4495505 ykgD Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851495.1 341784 D 405955 CDS YP_851496.1 117622583 4495506 343165..343884 1 NC_008563.1 hypothetical protein 343884 ykgE 4495506 ykgE Escherichia coli APEC O1 hypothetical protein YP_851496.1 343165 D 405955 CDS YP_851497.1 117622584 4495507 344022..345323 1 NC_008563.1 hypothetical protein 345323 ykgG 4495507 ykgG Escherichia coli APEC O1 hypothetical protein YP_851497.1 344022 D 405955 CDS YP_851498.1 117622585 4495508 345163..346011 1 NC_008563.1 hypothetical protein 346011 ykgG 4495508 ykgG Escherichia coli APEC O1 hypothetical protein YP_851498.1 345163 D 405955 CDS YP_851499.1 117622586 4495509 complement(346254..346922) 1 NC_008563.1 hypothetical protein 346922 ykgH 4495509 ykgH Escherichia coli APEC O1 hypothetical protein YP_851499.1 346254 R 405955 CDS YP_851500.1 117622587 4495510 complement(347106..349418) 1 NC_008563.1 hypothetical protein 349418 4495510 APECO1_1684 Escherichia coli APEC O1 hypothetical protein YP_851500.1 347106 R 405955 CDS YP_851501.1 117622588 4495511 complement(349445..350206) 1 NC_008563.1 hypothetical protein 350206 4495511 APECO1_1683 Escherichia coli APEC O1 hypothetical protein YP_851501.1 349445 R 405955 CDS YP_851502.1 117622589 4495512 complement(350360..351154) 1 NC_008563.1 hypothetical protein 351154 4495512 APECO1_1682 Escherichia coli APEC O1 hypothetical protein YP_851502.1 350360 R 405955 CDS YP_851503.1 117622590 4495513 complement(351484..352086) 1 NC_008563.1 hypothetical protein 352086 4495513 APECO1_1681 Escherichia coli APEC O1 hypothetical protein YP_851503.1 351484 R 405955 CDS YP_851504.1 117622591 4495514 352811..353092 1 NC_008563.1 hypothetical protein 353092 4495514 APECO1_1680 Escherichia coli APEC O1 hypothetical protein YP_851504.1 352811 D 405955 CDS YP_851505.2 229775979 4495515 complement(353117..354805) 1 NC_008563.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 354805 betA 4495515 betA Escherichia coli APEC O1 choline dehydrogenase YP_851505.2 353117 R 405955 CDS YP_851506.1 117622593 4495516 complement(354819..356294) 1 NC_008563.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 356294 betB 4495516 betB Escherichia coli APEC O1 betaine aldehyde dehydrogenase YP_851506.1 354819 R 405955 CDS YP_851507.1 117622594 4493869 complement(356305..356901) 1 NC_008563.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 356901 betI 4493869 betI Escherichia coli APEC O1 transcriptional regulator BetI YP_851507.1 356305 R 405955 CDS YP_851508.1 117622595 4493870 357021..359054 1 NC_008563.1 proton-motive-force-driven choline transporter; choline transport protein BetT 359054 betT 4493870 betT Escherichia coli APEC O1 choline transport protein BetT YP_851508.1 357021 D 405955 CDS YP_851509.1 117622596 4493871 359926..361020 1 NC_008563.1 DNA-binding transcriptional regulator 361020 yahA 4493871 yahA Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851509.1 359926 D 405955 CDS YP_851510.1 117622597 4493872 complement(361062..361994) 1 NC_008563.1 DNA-binding transcriptional regulator 361994 yahB 4493872 yahB Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851510.1 361062 R 405955 CDS YP_851511.1 117622598 4493873 complement(362086..362583) 1 NC_008563.1 hypothetical protein 362583 yahC 4493873 yahC Escherichia coli APEC O1 hypothetical protein YP_851511.1 362086 R 405955 CDS YP_851512.1 117622599 4493874 362841..363446 1 NC_008563.1 transcription factor 363446 yahD 4493874 yahD Escherichia coli APEC O1 transcription factor YP_851512.1 362841 D 405955 CDS YP_851513.1 117622600 4493875 363486..364349 1 NC_008563.1 hypothetical protein 364349 yahE 4493875 yahE Escherichia coli APEC O1 hypothetical protein YP_851513.1 363486 D 405955 CDS YP_851514.1 117622601 4493876 364339..365886 1 NC_008563.1 acyl-CoA synthetase 365886 yahF 4493876 yahF Escherichia coli APEC O1 acyl-CoA synthetase YP_851514.1 364339 D 405955 CDS YP_851515.1 117622602 4493877 365886..367304 1 NC_008563.1 hypothetical protein 367304 4493877 APECO1_1669 Escherichia coli APEC O1 hypothetical protein YP_851515.1 365886 D 405955 CDS YP_851516.1 117622603 4493878 367458..368408 1 NC_008563.1 carbamate kinase 368408 yahI 4493878 yahI Escherichia coli APEC O1 carbamate kinase YP_851516.1 367458 D 405955 CDS YP_851517.1 117622604 4493879 368418..369800 1 NC_008563.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 369800 yahJ 4493879 yahJ Escherichia coli APEC O1 deaminase YP_851517.1 368418 D 405955 CDS YP_851518.1 117622605 4493880 370098..370508 1 NC_008563.1 hypothetical protein 370508 4493880 APECO1_1666 Escherichia coli APEC O1 hypothetical protein YP_851518.1 370098 D 405955 CDS YP_851519.1 117622606 4493881 370759..371745 1 NC_008563.1 periplasmic binding protein, substrate ribose 371745 4493881 APECO1_1665 Escherichia coli APEC O1 periplasmic binding protein, substrate ribose YP_851519.1 370759 D 405955 CDS YP_851520.1 117622607 4493882 371794..373278 1 NC_008563.1 sugar ABC transporter ATP-binding protein 373278 4493882 APECO1_1664 Escherichia coli APEC O1 sugar ABC transporter ATP-binding protein YP_851520.1 371794 D 405955 CDS YP_851521.1 117622608 4493883 373271..374242 1 NC_008563.1 ribose ABC transporter permease 374242 4493883 APECO1_1663 Escherichia coli APEC O1 ribose ABC transporter permease YP_851521.1 373271 D 405955 CDS YP_851522.1 117622609 4493884 374209..375195 1 NC_008563.1 permease component of transport system 375195 4493884 APECO1_1662 Escherichia coli APEC O1 permease component of transport system YP_851522.1 374209 D 405955 CDS YP_851523.1 117622610 4493885 375282..376331 1 NC_008563.1 zinc-type alcohol dehydrogenase-like protein YahK 376331 yahK 4493885 yahK Escherichia coli APEC O1 zinc-type alcohol dehydrogenase-like protein YahK YP_851523.1 375282 D 405955 CDS YP_851524.1 117622611 4493886 complement(377215..377886) 1 NC_008563.1 cytochrome subunit of dehydrogenase 377886 yahN 4493886 yahN Escherichia coli APEC O1 cytochrome subunit of dehydrogenase YP_851524.1 377215 R 405955 CDS YP_851525.1 117622612 4493887 378033..378308 1 NC_008563.1 hypothetical protein 378308 yahO 4493887 yahO Escherichia coli APEC O1 hypothetical protein YP_851525.1 378033 D 405955 CDS YP_851526.1 117622613 4494448 complement(378409..379995) 1 NC_008563.1 DNA-binding transcriptional activator 379995 prpR 4494448 prpR Escherichia coli APEC O1 DNA-binding transcriptional activator YP_851526.1 378409 R 405955 CDS YP_851527.1 117622614 4494449 380234..381124 1 NC_008563.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 381124 prpB 4494449 prpB Escherichia coli APEC O1 2-methylisocitrate lyase YP_851527.1 380234 D 405955 CDS YP_851528.1 117622615 4494450 381169..382338 1 NC_008563.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 382338 prpC 4494450 prpC Escherichia coli APEC O1 methylcitrate synthase YP_851528.1 381169 D 405955 CDS YP_851529.1 117622616 4494451 382372..383823 1 NC_008563.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 383823 prpD 4494451 prpD Escherichia coli APEC O1 2-methylcitrate dehydratase YP_851529.1 382372 D 405955 CDS YP_851530.1 117622617 4494452 383863..385749 1 NC_008563.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 385749 prpE 4494452 prpE Escherichia coli APEC O1 propionyl-CoA synthetase YP_851530.1 383863 D 405955 CDS YP_851531.1 117622618 4494453 386074..387333 1 NC_008563.1 cytosine permease 387333 codB 4494453 codB Escherichia coli APEC O1 cytosine permease YP_851531.1 386074 D 405955 CDS YP_851532.1 117622619 4494454 387308..388606 1 NC_008563.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 388606 codA 4494454 codA Escherichia coli APEC O1 cytosine deaminase YP_851532.1 387308 D 405955 CDS YP_851533.1 117622620 4494455 complement(388727..389389) 1 NC_008563.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 389389 lacA 4494455 lacA Escherichia coli APEC O1 galactoside O-acetyltransferase YP_851533.1 388727 R 405955 CDS YP_851534.1 117622621 4494456 complement(389404..390657) 1 NC_008563.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 390657 lacY 4494456 lacY Escherichia coli APEC O1 galactoside permease YP_851534.1 389404 R 405955 CDS YP_851535.1 117622622 4494457 complement(390709..393783) 1 NC_008563.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 393783 lacZ 4494457 lacZ Escherichia coli APEC O1 beta-D-galactosidase YP_851535.1 390709 R 405955 CDS YP_851536.1 117622623 4494458 complement(393907..394998) 1 NC_008563.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 394998 lacI 4494458 lacI Escherichia coli APEC O1 lac repressor YP_851536.1 393907 R 405955 CDS YP_851537.1 117622624 4494459 395191..395730 1 NC_008563.1 nucleoprotein/polynucleotide-associated enzyme 395730 yaiL 4494459 yaiL Escherichia coli APEC O1 nucleoprotein/polynucleotide-associated enzyme YP_851537.1 395191 D 405955 CDS YP_851538.1 117622625 4494460 complement(395956..396789) 1 NC_008563.1 hypothetical protein 396789 yaiM 4494460 yaiM Escherichia coli APEC O1 hypothetical protein YP_851538.1 395956 R 405955 CDS YP_851539.1 117622626 4494461 complement(396882..397991) 1 NC_008563.1 glutathione-dependent formaldehyde dehydrogenase 397991 adhC 4494461 adhC Escherichia coli APEC O1 glutathione-dependent formaldehyde dehydrogenase YP_851539.1 396882 R 405955 CDS YP_851540.1 117622627 4494462 complement(398026..398322) 1 NC_008563.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 398322 frmR 4494462 frmR Escherichia coli APEC O1 regulator protein FrmR YP_851540.1 398026 R 405955 CDS YP_851541.1 117622628 4494463 complement(398490..399263) 1 NC_008563.1 hypothetical protein 399263 yaiO 4494463 yaiO Escherichia coli APEC O1 hypothetical protein YP_851541.1 398490 R 405955 CDS YP_851542.1 117622629 4494464 complement(399265..399975) 1 NC_008563.1 transferase 399975 4494464 APECO1_1642 Escherichia coli APEC O1 transferase YP_851542.1 399265 R 405955 CDS YP_851543.1 117622630 4494465 complement(399824..401020) 1 NC_008563.1 glucosyltransferase 401020 yaiP 4494465 yaiP Escherichia coli APEC O1 glucosyltransferase YP_851543.1 399824 R 405955 CDS YP_851544.1 117622631 4494466 complement(401030..401716) 1 NC_008563.1 hypothetical protein 401716 4494466 APECO1_1640 Escherichia coli APEC O1 hypothetical protein YP_851544.1 401030 R 405955 CDS YP_851545.1 117622632 4494467 402247..403266 1 NC_008563.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 403266 tauA 4494467 tauA Escherichia coli APEC O1 taurine transporter substrate binding subunit YP_851545.1 402247 D 405955 CDS YP_851546.1 117622633 4491940 403279..404046 1 NC_008563.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 404046 tauB 4491940 tauB Escherichia coli APEC O1 taurine transporter ATP-binding subunit YP_851546.1 403279 D 405955 CDS YP_851547.1 117622634 4491941 404043..404870 1 NC_008563.1 taurine transporter subunit 404870 tauC 4491941 tauC Escherichia coli APEC O1 taurine transporter subunit YP_851547.1 404043 D 405955 CDS YP_851548.1 117622635 4491942 404867..405718 1 NC_008563.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 405718 tauD 4491942 tauD Escherichia coli APEC O1 taurine dioxygenase YP_851548.1 404867 D 405955 CDS YP_851549.1 117622636 4491943 complement(405758..406765) 1 NC_008563.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 406765 hemB 4491943 hemB Escherichia coli APEC O1 delta-aminolevulinic acid dehydratase YP_851549.1 405758 R 405955 CDS YP_851550.1 117622637 4491944 407258..410245 1 NC_008563.1 structural protein 410245 4491944 APECO1_1634 Escherichia coli APEC O1 structural protein YP_851550.1 407258 D 405955 CDS YP_851551.1 117622638 4491945 410286..410954 1 NC_008563.1 DNA-binding transcriptional regulator 410954 yaiV 4491945 yaiV Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851551.1 410286 D 405955 CDS YP_851552.1 117622639 4491946 complement(410955..412085) 1 NC_008563.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 412085 ampH 4491946 ampH Escherichia coli APEC O1 beta-lactam binding protein AmpH YP_851552.1 410955 R 405955 CDS YP_851553.1 117622640 4491947 412458..413684 1 NC_008563.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 413684 sbmA 4491947 sbmA Escherichia coli APEC O1 transporter YP_851553.1 412458 D 405955 CDS YP_851554.1 117622641 4491948 413697..414791 1 NC_008563.1 hypothetical protein 414791 yaiW 4491948 yaiW Escherichia coli APEC O1 hypothetical protein YP_851554.1 413697 D 405955 CDS YP_851555.1 117622642 4491949 complement(414850..415158) 1 NC_008563.1 hypothetical protein 415158 4491949 APECO1_1629 Escherichia coli APEC O1 hypothetical protein YP_851555.1 414850 R 405955 CDS YP_851556.1 117622643 4491950 415286..415630 1 NC_008563.1 hypothetical protein 415630 yaiZ 4491950 yaiZ Escherichia coli APEC O1 hypothetical protein YP_851556.1 415286 D 405955 CDS YP_851557.1 117622644 4491951 complement(415654..416748) 1 NC_008563.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 416748 ddl 4491951 ddl Escherichia coli APEC O1 D-alanyl-alanine synthetase A YP_851557.1 415654 R 405955 CDS YP_851558.1 117622645 4491952 417211..417471 1 NC_008563.1 hypothetical protein 417471 yaiB 4491952 yaiB Escherichia coli APEC O1 hypothetical protein YP_851558.1 417211 D 405955 CDS YP_851559.1 117622646 4491953 417572..418987 1 NC_008563.1 alkaline phosphatase 418987 phoA 4491953 phoA Escherichia coli APEC O1 alkaline phosphatase YP_851559.1 417572 D 405955 CDS YP_851560.1 117622647 4491954 419088..419426 1 NC_008563.1 hypothetical protein 419426 psiF 4491954 psiF Escherichia coli APEC O1 hypothetical protein YP_851560.1 419088 D 405955 CDS YP_851561.1 117622648 4491955 419528..420643 1 NC_008563.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 420643 adrA 4491955 adrA Escherichia coli APEC O1 diguanylate cyclase AdrA YP_851561.1 419528 D 405955 CDS YP_851562.1 117622649 4491956 complement(420660..421469) 1 NC_008563.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 421469 proC 4491956 proC Escherichia coli APEC O1 pyrroline-5-carboxylate reductase YP_851562.1 420660 R 405955 CDS YP_851563.1 117622650 4491957 421589..422047 1 NC_008563.1 hypothetical protein 422047 4491957 APECO1_1621 Escherichia coli APEC O1 hypothetical protein YP_851563.1 421589 D 405955 CDS YP_851564.1 117622651 4491958 422230..422754 1 NC_008563.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 422754 aroL 4491958 aroL Escherichia coli APEC O1 shikimate kinase YP_851564.1 422230 D 405955 CDS YP_851565.1 117622652 4492464 complement(422744..423067) 1 NC_008563.1 hypothetical protein 423067 4492464 APECO1_1619 Escherichia coli APEC O1 hypothetical protein YP_851565.1 422744 R 405955 CDS YP_851566.1 117622653 4492465 423253..423930 1 NC_008563.1 hypothetical protein 423930 aroM 4492465 aroM Escherichia coli APEC O1 hypothetical protein YP_851566.1 423253 D 405955 CDS YP_851567.1 117622654 4492466 424002..424286 1 NC_008563.1 hypothetical protein 424286 4492466 APECO1_1617 Escherichia coli APEC O1 hypothetical protein YP_851567.1 424002 D 405955 CDS YP_851568.1 117622655 4492467 complement(424933..425790) 1 NC_008563.1 Required for efficient pilin antigenic variation; recombination associated protein 425790 rdgC 4492467 rdgC Escherichia coli APEC O1 recombination associated protein YP_851568.1 424933 R 405955 CDS YP_851569.1 117622656 4492468 425844..426878 1 NC_008563.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 426878 yajF 4492468 yajF Escherichia coli APEC O1 fructokinase YP_851569.1 425844 D 405955 CDS YP_851570.1 117622657 4492469 complement(427147..428367) 1 NC_008563.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 428367 araJ 4492469 araJ Escherichia coli APEC O1 MFS transport protein AraJ YP_851570.1 427147 R 405955 CDS YP_851571.1 117622658 4492470 complement(428457..431600) 1 NC_008563.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 431600 sbcC 4492470 sbcC Escherichia coli APEC O1 exonuclease subunit SbcC YP_851571.1 428457 R 405955 CDS YP_851572.1 117622659 4492471 complement(431597..432823) 1 NC_008563.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 432823 sbcD 4492471 sbcD Escherichia coli APEC O1 exonuclease subunit SbcD YP_851572.1 431597 R 405955 CDS YP_851573.1 117622660 4492472 432989..433678 1 NC_008563.1 sensor is PhoR; two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 433678 phoB 4492472 phoB Escherichia coli APEC O1 transcriptional regulator PhoB YP_851573.1 432989 D 405955 CDS YP_851574.1 117622661 4492473 433736..435031 1 NC_008563.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 435031 phoR 4492473 phoR Escherichia coli APEC O1 phosphate regulon sensor protein YP_851574.1 433736 D 405955 CDS YP_851575.1 117622662 4492474 435438..436757 1 NC_008563.1 branched-chain amino acid transport system II carrier protein 436757 brnQ 4492474 brnQ Escherichia coli APEC O1 branched-chain amino acid transport system II carrier protein YP_851575.1 435438 D 405955 CDS YP_851576.1 117622663 4492475 436833..438206 1 NC_008563.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 438206 proY 4492475 proY Escherichia coli APEC O1 proline-specific permease YP_851576.1 436833 D 405955 CDS YP_851577.1 117622664 4492476 438362..440179 1 NC_008563.1 maltodextrin glucosidase 440179 malZ 4492476 malZ Escherichia coli APEC O1 maltodextrin glucosidase YP_851577.1 438362 D 405955 CDS YP_851578.1 117622665 4492477 complement(440184..440822) 1 NC_008563.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 440822 yajB 4492477 yajB Escherichia coli APEC O1 acyl carrier protein phosphodiesterase YP_851578.1 440184 R 405955 CDS YP_851579.1 117622666 4492478 440984..442054 1 NC_008563.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 442054 queA 4492478 queA Escherichia coli APEC O1 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_851579.1 440984 D 405955 CDS YP_851580.1 117622667 4492479 442109..443236 1 NC_008563.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 443236 tgt 4492479 tgt Escherichia coli APEC O1 queuine tRNA-ribosyltransferase YP_851580.1 442109 D 405955 CDS YP_851581.1 117622668 4492480 443259..443591 1 NC_008563.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 443591 yajC 4492480 yajC Escherichia coli APEC O1 preprotein translocase subunit YajC YP_851581.1 443259 D 405955 CDS YP_851582.1 117622669 4492481 443619..445466 1 NC_008563.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 445466 secD 4492481 secD Escherichia coli APEC O1 preprotein translocase subunit SecD YP_851582.1 443619 D 405955 CDS YP_851583.1 117622670 4492482 445432..446448 1 NC_008563.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 446448 secF 4492482 secF Escherichia coli APEC O1 preprotein translocase subunit SecF YP_851583.1 445432 D 405955 CDS YP_851584.1 117622671 4492483 446509..446925 1 NC_008563.1 hypothetical protein 446925 yajD 4492483 yajD Escherichia coli APEC O1 hypothetical protein YP_851584.1 446509 D 405955 CDS YP_851585.1 117622672 4493703 complement(446963..447847) 1 NC_008563.1 nucleoside-specific channel-forming protein Tsx 447847 tsx 4493703 tsx Escherichia coli APEC O1 nucleoside-specific channel-forming protein Tsx YP_851585.1 446963 R 405955 CDS YP_851586.1 117622673 4493704 complement(448145..448744) 1 NC_008563.1 hypothetical protein 448744 yajI 4493704 yajI Escherichia coli APEC O1 hypothetical protein YP_851586.1 448145 R 405955 CDS YP_851587.1 117622674 4493705 448835..449284 1 NC_008563.1 NrdR family transcriptional regulator 449284 nrdR 4493705 nrdR Escherichia coli APEC O1 NrdR family transcriptional regulator YP_851587.1 448835 D 405955 CDS YP_851588.1 117622675 4493706 449288..450391 1 NC_008563.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 450391 ribD 4493706 ribD Escherichia coli APEC O1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_851588.1 449288 D 405955 CDS YP_851589.1 117622676 4493707 450384..450950 1 NC_008563.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 450950 ribH 4493707 ribH Escherichia coli APEC O1 6,7-dimethyl-8-ribityllumazine synthase YP_851589.1 450384 D 405955 CDS YP_851591.1 117622678 4493709 451467..452444 1 NC_008563.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 452444 thiL 4493709 thiL Escherichia coli APEC O1 thiamine monophosphate kinase YP_851591.1 451467 D 405955 CDS YP_851592.1 117622679 4493710 452422..452940 1 NC_008563.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 452940 pgpA 4493710 pgpA Escherichia coli APEC O1 phosphatidylglycerophosphatase A YP_851592.1 452422 D 405955 CDS YP_851593.1 117622680 4493711 complement(452994..453968) 1 NC_008563.1 oxidoreductase, NAD(P)-binding 453968 yajO 4493711 yajO Escherichia coli APEC O1 oxidoreductase, NAD(P)-binding YP_851593.1 452994 R 405955 CDS YP_851594.1 117622681 4493712 complement(454023..455885) 1 NC_008563.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 455885 dxs 4493712 dxs Escherichia coli APEC O1 1-deoxy-D-xylulose-5-phosphate synthase YP_851594.1 454023 R 405955 CDS YP_851595.1 117622682 4493713 complement(455910..456809) 1 NC_008563.1 geranyltranstransferase 456809 ispA 4493713 ispA Escherichia coli APEC O1 geranyltranstransferase YP_851595.1 455910 R 405955 CDS YP_851596.1 117622683 4493714 457257..458705 1 NC_008563.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 458705 thiI 4493714 thiI Escherichia coli APEC O1 thiamine biosynthesis protein ThiI YP_851596.1 457257 D 405955 CDS YP_851597.1 117622684 4493715 complement(458759..459355) 1 NC_008563.1 DJ-1 family protein 459355 thiJ 4493715 thiJ Escherichia coli APEC O1 DJ-1 family protein YP_851597.1 458759 R 405955 CDS YP_851598.1 117622685 4493716 complement(459312..460223) 1 NC_008563.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 460223 apbA 4493716 apbA Escherichia coli APEC O1 2-dehydropantoate 2-reductase YP_851598.1 459312 R 405955 CDS YP_851599.1 117622686 4493717 460373..460882 1 NC_008563.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 460882 yajQ 4493717 yajQ Escherichia coli APEC O1 nucleotide-binding protein YP_851599.1 460373 D 405955 CDS YP_851600.1 117622687 4493718 complement(461010..462380) 1 NC_008563.1 hypothetical protein 462380 yajR 4493718 yajR Escherichia coli APEC O1 hypothetical protein YP_851600.1 461010 R 405955 CDS YP_851601.1 117622688 4493719 complement(462523..463458) 1 NC_008563.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 463458 cyoE 4493719 cyoE Escherichia coli APEC O1 protoheme IX farnesyltransferase YP_851601.1 462523 R 405955 CDS YP_851602.1 117622689 4493720 complement(463425..463835) 1 NC_008563.1 cytochrome o ubiquinol oxidase subunit IV 463835 cyoD 4493720 cyoD Escherichia coli APEC O1 cytochrome o ubiquinol oxidase subunit IV YP_851602.1 463425 R 405955 CDS YP_851603.1 117622690 4493721 complement(463754..464368) 1 NC_008563.1 cytochrome o ubiquinol oxidase subunit III 464368 cyoC 4493721 cyoC Escherichia coli APEC O1 cytochrome o ubiquinol oxidase subunit III YP_851603.1 463754 R 405955 CDS YP_851604.1 117622691 4492874 complement(464358..466349) 1 NC_008563.1 cytochrome o ubiquinol oxidase subunit I 466349 cyoB 4492874 cyoB Escherichia coli APEC O1 cytochrome o ubiquinol oxidase subunit I YP_851604.1 464358 R 405955 CDS YP_851605.1 117622692 4492875 complement(466371..467327) 1 NC_008563.1 cytochrome o ubiquinol oxidase subunit II 467327 cyoA 4492875 cyoA Escherichia coli APEC O1 cytochrome o ubiquinol oxidase subunit II YP_851605.1 466371 R 405955 CDS YP_851606.1 117622693 4492876 complement(467786..469261) 1 NC_008563.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 469261 ampG 4492876 ampG Escherichia coli APEC O1 muropeptide transporter YP_851606.1 467786 R 405955 CDS YP_851607.1 117622694 4492877 complement(469305..469985) 1 NC_008563.1 hypothetical protein 469985 yajG 4492877 yajG Escherichia coli APEC O1 hypothetical protein YP_851607.1 469305 R 405955 CDS YP_851608.2 162317585 4492878 470188..470505 1 NC_008563.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 470505 bolA 4492878 bolA Escherichia coli APEC O1 transcriptional regulator BolA YP_851608.2 470188 D 405955 CDS YP_851609.1 117622696 4492879 470849..472138 1 NC_008563.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 472138 tig 4492879 tig Escherichia coli APEC O1 trigger factor YP_851609.1 470849 D 405955 CDS YP_851610.1 117622697 4492880 472393..473016 1 NC_008563.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 473016 clpP 4492880 clpP Escherichia coli APEC O1 ATP-dependent Clp protease proteolytic subunit YP_851610.1 472393 D 405955 CDS YP_851611.1 117622698 4492881 473142..474416 1 NC_008563.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 474416 clpX 4492881 clpX Escherichia coli APEC O1 ATP-dependent protease ATP-binding subunit ClpX YP_851611.1 473142 D 405955 CDS YP_851612.1 117622699 4492882 474559..476958 1 NC_008563.1 DNA-binding ATP-dependent protease La 476958 lon 4492882 lon Escherichia coli APEC O1 DNA-binding ATP-dependent protease La YP_851612.1 474559 D 405955 CDS YP_851613.1 117622700 4492883 477167..477439 1 NC_008563.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 477439 hupB 4492883 hupB Escherichia coli APEC O1 transcriptional regulator HU subunit beta YP_851613.1 477167 D 405955 CDS YP_851614.1 117622701 4492884 477631..479502 1 NC_008563.1 peptidyl-prolyl cis-trans isomerase 479502 ppiD 4492884 ppiD Escherichia coli APEC O1 peptidyl-prolyl cis-trans isomerase YP_851614.1 477631 D 405955 CDS YP_851615.1 117622702 4492885 479653..480024 1 NC_008563.1 hypothetical protein 480024 ybaV 4492885 ybaV Escherichia coli APEC O1 hypothetical protein YP_851615.1 479653 D 405955 CDS YP_851616.1 117622703 4492886 480130..480528 1 NC_008563.1 hypothetical protein 480528 ybaW 4492886 ybaW Escherichia coli APEC O1 hypothetical protein YP_851616.1 480130 D 405955 CDS YP_851617.1 117622704 4492887 complement(480580..481275) 1 NC_008563.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 481275 4492887 APECO1_1567 Escherichia coli APEC O1 queuosine biosynthesis protein QueC YP_851617.1 480580 R 405955 CDS YP_851618.1 117622705 4492888 complement(481340..483040) 1 NC_008563.1 hypothetical protein 483040 ybaE 4492888 ybaE Escherichia coli APEC O1 hypothetical protein YP_851618.1 481340 R 405955 CDS YP_851619.1 117622706 4492889 483128..483958 1 NC_008563.1 hypothetical protein 483958 cof 4492889 cof Escherichia coli APEC O1 hypothetical protein YP_851619.1 483128 D 405955 CDS YP_851620.1 117622707 4492890 483958..484569 1 NC_008563.1 transcriptional regulator YbaO 484569 ybaO 4492890 ybaO Escherichia coli APEC O1 transcriptional regulator YbaO YP_851620.1 483958 D 405955 CDS YP_851621.1 117622708 4492891 484599..486371 1 NC_008563.1 multidrug transporter membrane\ATP-binding components 486371 mdlA 4492891 mdlA Escherichia coli APEC O1 multidrug transporter membrane\ATP-binding components YP_851621.1 484599 D 405955 CDS YP_851622.2 229775978 4492892 486364..488145 1 NC_008563.1 multidrug transporter membrane\ATP-binding components 488145 mdlB 4492892 mdlB Escherichia coli APEC O1 multidrug transporter membrane\ATP-binding components YP_851622.2 486364 D 405955 CDS YP_851623.1 117622710 4492893 488188..488664 1 NC_008563.1 glutamine synthetase 488664 glnK 4492893 glnK Escherichia coli APEC O1 glutamine synthetase YP_851623.1 488188 D 405955 CDS YP_851624.1 117622711 4494024 488694..489980 1 NC_008563.1 ammonium transporter 489980 amtB 4494024 amtB Escherichia coli APEC O1 ammonium transporter YP_851624.1 488694 D 405955 CDS YP_851625.1 117622712 4494025 complement(490029..490889) 1 NC_008563.1 acyl-CoA thioesterase II 490889 tesB 4494025 tesB Escherichia coli APEC O1 acyl-CoA thioesterase II YP_851625.1 490029 R 405955 CDS YP_851626.1 117622713 4494026 491107..491679 1 NC_008563.1 lipoprotein 491679 ybaY 4494026 ybaY Escherichia coli APEC O1 lipoprotein YP_851626.1 491107 D 405955 CDS YP_851627.1 117622714 4494027 complement(491710..492099) 1 NC_008563.1 hypothetical protein 492099 ybaZ 4494027 ybaZ Escherichia coli APEC O1 hypothetical protein YP_851627.1 491710 R 405955 CDS YP_851628.1 117622715 4494028 492400..492753 1 NC_008563.1 hypothetical protein 492753 4494028 APECO1_1556 Escherichia coli APEC O1 hypothetical protein YP_851628.1 492400 D 405955 CDS YP_851629.1 117622716 4494029 complement(492795..494351) 1 NC_008563.1 hypothetical protein 494351 ylaB 4494029 ylaB Escherichia coli APEC O1 hypothetical protein YP_851629.1 492795 R 405955 CDS YP_851630.1 117622717 4494030 complement(494509..495018) 1 NC_008563.1 hypothetical protein 495018 ylaC 4494030 ylaC Escherichia coli APEC O1 hypothetical protein YP_851630.1 494509 R 405955 CDS YP_851631.1 117622718 4494031 complement(495095..495646) 1 NC_008563.1 maltose O-acetyltransferase 495646 maa 4494031 maa Escherichia coli APEC O1 maltose O-acetyltransferase YP_851631.1 495095 R 405955 CDS YP_851632.1 117622719 4494032 complement(495820..496239) 1 NC_008563.1 Hha protein 496239 hha 4494032 hha Escherichia coli APEC O1 Hha protein YP_851632.1 495820 R 405955 CDS YP_851633.1 117622720 4494033 complement(496983..500132) 1 NC_008563.1 acridine efflux pump 500132 acrB 4494033 acrB Escherichia coli APEC O1 acridine efflux pump YP_851633.1 496983 R 405955 CDS YP_851634.1 117622721 4494034 complement(500155..501348) 1 NC_008563.1 acriflavine resistance protein A precursor 501348 acrA 4494034 acrA Escherichia coli APEC O1 acriflavine resistance protein A precursor YP_851634.1 500155 R 405955 CDS YP_851635.1 117622722 4494035 501490..502137 1 NC_008563.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 502137 acrR 4494035 acrR Escherichia coli APEC O1 DNA-binding transcriptional repressor AcrR YP_851635.1 501490 D 405955 CDS YP_851636.1 117622723 4494036 502265..505627 1 NC_008563.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 505627 kefA 4494036 kefA Escherichia coli APEC O1 potassium efflux protein KefA YP_851636.1 502265 D 405955 CDS YP_851637.1 117622724 4494037 complement(506014..506541) 1 NC_008563.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 506541 priC 4494037 priC Escherichia coli APEC O1 primosomal replication protein N'' YP_851637.1 506014 R 405955 CDS YP_851638.1 117622725 4494038 506611..506988 1 NC_008563.1 hypothetical protein 506988 ybaN 4494038 ybaN Escherichia coli APEC O1 hypothetical protein YP_851638.1 506611 D 405955 CDS YP_851639.1 117622726 4494039 507108..507692 1 NC_008563.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 507692 apt 4494039 apt Escherichia coli APEC O1 adenine phosphoribosyltransferase YP_851639.1 507108 D 405955 CDS YP_851640.1 117622727 4494040 507821..509752 1 NC_008563.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 509752 dnaX 4494040 dnaX Escherichia coli APEC O1 DNA polymerase III subunits gamma and tau YP_851640.1 507821 D 405955 CDS YP_851641.1 117622728 4494041 509805..510134 1 NC_008563.1 hypothetical protein 510134 4494041 APECO1_1544 Escherichia coli APEC O1 hypothetical protein YP_851641.1 509805 D 405955 CDS YP_851642.1 117622729 4494042 510134..510739 1 NC_008563.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 510739 recR 4494042 recR Escherichia coli APEC O1 recombination protein RecR YP_851642.1 510134 D 405955 CDS YP_851643.1 117622730 4493664 510849..512723 1 NC_008563.1 molecular chaperone; heat shock protein 90 512723 htpG 4493664 htpG Escherichia coli APEC O1 heat shock protein 90 YP_851643.1 510849 D 405955 CDS YP_851644.2 229775977 4493665 512904..513548 1 NC_008563.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 513548 adk 4493665 adk Escherichia coli APEC O1 adenylate kinase YP_851644.2 512904 D 405955 CDS YP_851645.1 117622732 4493666 513680..514642 1 NC_008563.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 514642 hemH 4493666 hemH Escherichia coli APEC O1 ferrochelatase YP_851645.1 513680 D 405955 CDS YP_851646.1 117622733 4493667 complement(514639..515598) 1 NC_008563.1 acetyl esterase 515598 ybaC 4493667 ybaC Escherichia coli APEC O1 acetyl esterase YP_851646.1 514639 R 405955 CDS YP_851647.1 117622734 4493668 515750..517054 1 NC_008563.1 inosine-guanosine kinase 517054 gsk 4493668 gsk Escherichia coli APEC O1 inosine-guanosine kinase YP_851647.1 515750 D 405955 CDS YP_851648.1 117622735 4493669 complement(517184..518860) 1 NC_008563.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 518860 ybaL 4493669 ybaL Escherichia coli APEC O1 cation:proton antiport protein YP_851648.1 517184 R 405955 CDS YP_851649.1 117622736 4493670 complement(519099..520319) 1 NC_008563.1 fosmidomycin resistance protein 520319 fsr 4493670 fsr Escherichia coli APEC O1 fosmidomycin resistance protein YP_851649.1 519099 R 405955 CDS YP_851650.1 117622737 4493671 520537..522189 1 NC_008563.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 522189 ushA 4493671 ushA Escherichia coli APEC O1 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_851650.1 520537 D 405955 CDS YP_851651.1 117622738 4493672 complement(522227..522730) 1 NC_008563.1 hypothetical protein 522730 4493672 APECO1_1534 Escherichia coli APEC O1 hypothetical protein YP_851651.1 522227 R 405955 CDS YP_851652.1 117622739 4493673 complement(522727..523527) 1 NC_008563.1 hypothetical protein 523527 4493673 APECO1_1533 Escherichia coli APEC O1 hypothetical protein YP_851652.1 522727 R 405955 CDS YP_851653.1 117622740 4493674 complement(523551..524030) 1 NC_008563.1 hypothetical protein 524030 ybaK 4493674 ybaK Escherichia coli APEC O1 hypothetical protein YP_851653.1 523551 R 405955 CDS YP_851654.1 117622741 4493675 complement(524234..525028) 1 NC_008563.1 ligase 525028 ybaP 4493675 ybaP Escherichia coli APEC O1 ligase YP_851654.1 524234 R 405955 CDS YP_851655.1 117622742 4493676 525161..525463 1 NC_008563.1 hypothetical protein 525463 4493676 APECO1_1530 Escherichia coli APEC O1 hypothetical protein YP_851655.1 525161 D 405955 CDS YP_851656.1 117622743 4493677 525499..525840 1 NC_008563.1 DNA-binding transcriptional regulator 525840 ybaQ 4493677 ybaQ Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851656.1 525499 D 405955 CDS YP_851657.1 117622744 4493678 complement(525898..528402) 1 NC_008563.1 copper exporting ATPase 528402 copA 4493678 copA Escherichia coli APEC O1 copper exporting ATPase YP_851657.1 525898 R 405955 CDS YP_851658.1 117622745 4493679 528664..529596 1 NC_008563.1 catalyzes the formation of glutamate from glutamine; glutaminase 529596 ybaS 4493679 ybaS Escherichia coli APEC O1 glutaminase YP_851658.1 528664 D 405955 CDS YP_851659.1 117622746 4493680 529599..530891 1 NC_008563.1 transporter 530891 ybaT 4493680 ybaT Escherichia coli APEC O1 transporter YP_851659.1 529599 D 405955 CDS YP_851660.1 117622747 4493681 531016..531423 1 NC_008563.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 531423 ybbI 4493681 ybbI Escherichia coli APEC O1 DNA-binding transcriptional regulator CueR YP_851660.1 531016 D 405955 CDS YP_851661.1 117622748 4493682 complement(531627..532049) 1 NC_008563.1 hypothetical protein 532049 4493682 APECO1_1524 Escherichia coli APEC O1 hypothetical protein YP_851661.1 531627 R 405955 CDS YP_851662.1 117622749 4493683 complement(532135..533151) 1 NC_008563.1 adhesin/invasin-like protein 533151 4493683 APECO1_1523 Escherichia coli APEC O1 adhesin/invasin-like protein YP_851662.1 532135 R 405955 CDS YP_851663.1 117622750 4493606 533518..533880 1 NC_008563.1 hypothetical protein 533880 4493606 APECO1_1522 Escherichia coli APEC O1 hypothetical protein YP_851663.1 533518 D 405955 CDS YP_851664.1 117622751 4493607 complement(533983..534441) 1 NC_008563.1 hypothetical protein 534441 ybbJ 4493607 ybbJ Escherichia coli APEC O1 hypothetical protein YP_851664.1 533983 R 405955 CDS YP_851665.1 117622752 4493608 complement(534438..535355) 1 NC_008563.1 protease YbbK 535355 ybbK 4493608 ybbK Escherichia coli APEC O1 protease YbbK YP_851665.1 534438 R 405955 CDS YP_851666.1 117622753 4493609 535501..536178 1 NC_008563.1 ABC transporter ATP-binding protein 536178 ybbL 4493609 ybbL Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_851666.1 535501 D 405955 CDS YP_851667.1 117622754 4493610 536138..536944 1 NC_008563.1 metal resistance protein 536944 ybbM 4493610 ybbM Escherichia coli APEC O1 metal resistance protein YP_851667.1 536138 D 405955 CDS YP_851668.1 117622755 4493611 complement(537007..537897) 1 NC_008563.1 thioredoxin 537897 ybbN 4493611 ybbN Escherichia coli APEC O1 thioredoxin YP_851668.1 537007 R 405955 CDS YP_851669.1 117622756 4493612 complement(537922..538731) 1 NC_008563.1 short chain dehydrogenase 538731 ybbO 4493612 ybbO Escherichia coli APEC O1 short chain dehydrogenase YP_851669.1 537922 R 405955 CDS YP_851670.1 117622757 4493613 complement(538721..539377) 1 NC_008563.1 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 539377 tesA 4493613 tesA Escherichia coli APEC O1 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_851670.1 538721 R 405955 CDS YP_851671.1 117622758 4493614 539315..540001 1 NC_008563.1 ABC transporter ATP-binding protein 540001 ybbA 4493614 ybbA Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_851671.1 539315 D 405955 CDS YP_851672.1 117622759 4493615 539998..542412 1 NC_008563.1 hypothetical protein 542412 ybbP 4493615 ybbP Escherichia coli APEC O1 hypothetical protein YP_851672.1 539998 D 405955 CDS YP_851673.1 117622760 4493616 complement(542471..543565) 1 NC_008563.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 543565 ybbB 4493616 ybbB Escherichia coli APEC O1 tRNA 2-selenouridine synthase YP_851673.1 542471 R 405955 CDS YP_851674.1 117622761 4493617 complement(543634..544560) 1 NC_008563.1 activator of the allDC-ylbA operon involved in allantoin utilization; AllS family transcriptional regulator 544560 ybbS 4493617 ybbS Escherichia coli APEC O1 AllS family transcriptional regulator YP_851674.1 543634 R 405955 CDS YP_851675.1 117622762 4493618 544790..545272 1 NC_008563.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 545272 allA 4493618 allA Escherichia coli APEC O1 ureidoglycolate hydrolase YP_851675.1 544790 D 405955 CDS YP_851676.1 117622763 4493619 545350..546165 1 NC_008563.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 546165 ybbU 4493619 ybbU Escherichia coli APEC O1 DNA-binding transcriptional repressor AllR YP_851676.1 545350 D 405955 CDS YP_851677.1 117622764 4493620 546165..548036 1 NC_008563.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 548036 gcl 4493620 gcl Escherichia coli APEC O1 glyoxylate carboligase YP_851677.1 546165 D 405955 CDS YP_851678.1 117622765 4493621 548049..548825 1 NC_008563.1 hydroxypyruvate isomerase 548825 hyi 4493621 hyi Escherichia coli APEC O1 hydroxypyruvate isomerase YP_851678.1 548049 D 405955 CDS YP_851679.1 117622766 4493622 548925..549803 1 NC_008563.1 2-hydroxy-3-oxopropionate reductase 549803 ybbQ 4493622 ybbQ Escherichia coli APEC O1 2-hydroxy-3-oxopropionate reductase YP_851679.1 548925 D 405955 CDS YP_851680.1 117622767 4493623 549973..551427 1 NC_008563.1 allantoin permease 551427 ybbW 4493623 ybbW Escherichia coli APEC O1 allantoin permease YP_851680.1 549973 D 405955 CDS YP_851681.1 117622768 4493624 551487..552848 1 NC_008563.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 552848 allB 4493624 allB Escherichia coli APEC O1 allantoinase YP_851681.1 551487 D 405955 CDS YP_851682.1 117622769 4494856 552898..554205 1 NC_008563.1 purine permease YbbY 554205 ybbY 4494856 ybbY Escherichia coli APEC O1 purine permease YbbY YP_851682.1 552898 D 405955 CDS YP_851683.1 117622770 4494857 554227..555372 1 NC_008563.1 glycerate kinase 555372 glxK 4494857 glxK Escherichia coli APEC O1 glycerate kinase YP_851683.1 554227 D 405955 CDS YP_851684.1 117622771 4494858 complement(555501..556286) 1 NC_008563.1 hypothetical protein 556286 ylbA 4494858 ylbA Escherichia coli APEC O1 hypothetical protein YP_851684.1 555501 R 405955 CDS YP_851685.1 117622772 4494859 complement(556297..557532) 1 NC_008563.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 557532 allC 4494859 allC Escherichia coli APEC O1 allantoate amidohydrolase YP_851685.1 556297 R 405955 CDS YP_851686.1 117622773 4494860 complement(557554..558603) 1 NC_008563.1 ureidoglycolate dehydrogenase 558603 allD 4494860 allD Escherichia coli APEC O1 ureidoglycolate dehydrogenase YP_851686.1 557554 R 405955 CDS YP_851687.1 117622774 4494861 558920..560587 1 NC_008563.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 560587 fdrA 4494861 fdrA Escherichia coli APEC O1 membrane protein FdrA YP_851687.1 558920 D 405955 CDS YP_851688.1 117622775 4494862 560597..561856 1 NC_008563.1 hypothetical protein 561856 ylbE 4494862 ylbE Escherichia coli APEC O1 hypothetical protein YP_851688.1 560597 D 405955 CDS YP_851689.1 117622776 4494863 561867..562682 1 NC_008563.1 hypothetical protein 562682 ylbF 4494863 ylbF Escherichia coli APEC O1 hypothetical protein YP_851689.1 561867 D 405955 CDS YP_851690.1 117622777 4494864 562679..563572 1 NC_008563.1 carbamate kinase 563572 arcC 4494864 arcC Escherichia coli APEC O1 carbamate kinase YP_851690.1 562679 D 405955 CDS YP_851691.1 117622778 4494865 complement(563725..564792) 1 NC_008563.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 564792 purK 4494865 purK Escherichia coli APEC O1 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_851691.1 563725 R 405955 CDS YP_851692.1 117622779 4494866 complement(564789..565298) 1 NC_008563.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 565298 purE 4494866 purE Escherichia coli APEC O1 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_851692.1 564789 R 405955 CDS YP_851693.1 117622780 4494867 complement(565394..565723) 1 NC_008563.1 hypothetical protein 565723 4494867 APECO1_1491 Escherichia coli APEC O1 hypothetical protein YP_851693.1 565394 R 405955 CDS YP_851694.1 117622781 4494868 complement(565834..566556) 1 NC_008563.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 566556 ybbF 4494868 ybbF Escherichia coli APEC O1 UDP-2,3-diacylglucosamine hydrolase YP_851694.1 565834 R 405955 CDS YP_851696.1 117622783 4494870 567227..568612 1 NC_008563.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 568612 cysS 4494870 cysS Escherichia coli APEC O1 cysteinyl-tRNA synthetase YP_851696.1 567227 D 405955 CDS YP_851697.1 117622784 4494871 complement(568648..569169) 1 NC_008563.1 hypothetical protein 569169 4494871 APECO1_1487 Escherichia coli APEC O1 hypothetical protein YP_851697.1 568648 R 405955 CDS YP_851698.1 117622785 4494872 complement(569491..570357) 1 NC_008563.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 570357 folD 4494872 folD Escherichia coli APEC O1 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_851698.1 569491 R 405955 CDS YP_851699.1 117622786 4494873 complement(570712..571092) 1 NC_008563.1 prophage DLP12 integrase 571092 intD 4494873 intD Escherichia coli APEC O1 prophage DLP12 integrase YP_851699.1 570712 R 405955 CDS YP_851700.1 117622787 4494874 complement(571040..571447) 1 NC_008563.1 prophage DLP12 integrase 571447 intD 4494874 intD Escherichia coli APEC O1 prophage DLP12 integrase YP_851700.1 571040 R 405955 CDS YP_851701.1 117622788 4493850 complement(571757..572422) 1 NC_008563.1 hypothetical protein 572422 ybcY 4493850 ybcY Escherichia coli APEC O1 hypothetical protein YP_851701.1 571757 R 405955 CDS YP_851702.1 117622789 4493851 complement(572657..573610) 1 NC_008563.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 573610 ompT 4493851 ompT Escherichia coli APEC O1 outer membrane protease YP_851702.1 572657 R 405955 CDS YP_851703.1 117622790 4493852 complement(574268..575158) 1 NC_008563.1 hypothetical protein 575158 ybcH 4493852 ybcH Escherichia coli APEC O1 hypothetical protein YP_851703.1 574268 R 405955 CDS YP_851704.1 117622791 4493853 complement(575159..578131) 1 NC_008563.1 bacteriophage N4 receptor, outer membrane subunit 578131 nfrA 4493853 nfrA Escherichia coli APEC O1 bacteriophage N4 receptor, outer membrane subunit YP_851704.1 575159 R 405955 CDS YP_851705.1 117622792 4493854 complement(578118..580355) 1 NC_008563.1 bacteriophage N4 adsorption protein B 580355 nfrB 4493854 nfrB Escherichia coli APEC O1 bacteriophage N4 adsorption protein B YP_851705.1 578118 R 405955 CDS YP_851706.1 117622793 4493855 complement(580505..581947) 1 NC_008563.1 sensor kinase CusS 581947 cusS 4493855 cusS Escherichia coli APEC O1 sensor kinase CusS YP_851706.1 580505 R 405955 CDS YP_851707.1 117622794 4493856 complement(581937..582620) 1 NC_008563.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; CusR family transcriptional regulator 582620 ylcA 4493856 ylcA Escherichia coli APEC O1 CusR family transcriptional regulator YP_851707.1 581937 R 405955 CDS YP_851708.1 117622795 4493857 582777..584159 1 NC_008563.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 584159 cusC 4493857 cusC Escherichia coli APEC O1 copper/silver efflux system outer membrane protein CusC YP_851708.1 582777 D 405955 CDS YP_851709.1 117622796 4493858 584183..584515 1 NC_008563.1 copper-binding protein 584515 4493858 APECO1_1475 Escherichia coli APEC O1 copper-binding protein YP_851709.1 584183 D 405955 CDS YP_851710.1 117622797 4493859 584531..585754 1 NC_008563.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 585754 cusB 4493859 cusB Escherichia coli APEC O1 copper/silver efflux system membrane fusion protein CusB YP_851710.1 584531 D 405955 CDS YP_851711.1 117622798 4493864 585766..588909 1 NC_008563.1 copper/silver efflux system, membrane component 588909 cusA 4493864 cusA Escherichia coli APEC O1 copper/silver efflux system, membrane component YP_851711.1 585766 D 405955 CDS YP_851712.1 117622799 4493865 588975..590387 1 NC_008563.1 phenylalanine transporter 590387 pheP 4493865 pheP Escherichia coli APEC O1 phenylalanine transporter YP_851712.1 588975 D 405955 CDS YP_851713.1 117622800 4493866 complement(590469..591716) 1 NC_008563.1 hypothetical protein 591716 ybdG 4493866 ybdG Escherichia coli APEC O1 hypothetical protein YP_851713.1 590469 R 405955 CDS YP_851714.1 117622801 4493867 complement(591824..592477) 1 NC_008563.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 592477 nfnB 4493867 nfnB Escherichia coli APEC O1 dihydropteridine reductase YP_851714.1 591824 R 405955 CDS YP_851715.1 117622802 4493359 complement(592556..592939) 1 NC_008563.1 hypothetical protein 592939 ybdF 4493359 ybdF Escherichia coli APEC O1 hypothetical protein YP_851715.1 592556 R 405955 CDS YP_851716.1 117622803 4493360 complement(593318..594436) 1 NC_008563.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 594436 ybdK 4493360 ybdK Escherichia coli APEC O1 carboxylate-amine ligase YP_851716.1 593318 R 405955 CDS YP_851717.1 117622804 4493361 complement(594652..594921) 1 NC_008563.1 hypothetical protein 594921 4493361 APECO1_1467 Escherichia coli APEC O1 hypothetical protein YP_851717.1 594652 R 405955 CDS YP_851718.1 117622805 4493362 complement(595164..595934) 1 NC_008563.1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 595934 entD 4493362 entD Escherichia coli APEC O1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_851718.1 595164 R 405955 CDS YP_851719.2 229775976 4493363 complement(596253..598199) 1 NC_008563.1 ferrienterobactin receptor 598199 fepA 4493363 fepA Escherichia coli APEC O1 ferrienterobactin receptor YP_851719.2 596253 R 405955 CDS YP_851720.1 117622807 4493364 598442..599644 1 NC_008563.1 enterobactin/ferric enterobactin esterase 599644 fes 4493364 fes Escherichia coli APEC O1 enterobactin/ferric enterobactin esterase YP_851720.1 598442 D 405955 CDS YP_851721.1 117622808 4493365 599724..603743 1 NC_008563.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 603743 entF 4493365 entF Escherichia coli APEC O1 enterobactin synthase subunit F YP_851721.1 599724 D 405955 CDS YP_851722.1 117622809 4493366 603839..605092 1 NC_008563.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 605092 fepE 4493366 fepE Escherichia coli APEC O1 ferric enterobactin transport protein FepE YP_851722.1 603839 D 405955 CDS YP_851723.1 117622810 4493367 complement(605089..606222) 1 NC_008563.1 iron-enterobactin transporter ATP-binding protein 606222 fepC 4493367 fepC Escherichia coli APEC O1 iron-enterobactin transporter ATP-binding protein YP_851723.1 605089 R 405955 CDS YP_851724.1 117622811 4493368 complement(605901..606893) 1 NC_008563.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 606893 fepG 4493368 fepG Escherichia coli APEC O1 iron-enterobactin transporter permease YP_851724.1 605901 R 405955 CDS YP_851725.1 117622812 4493369 complement(606890..607906) 1 NC_008563.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 607906 fepD 4493369 fepD Escherichia coli APEC O1 iron-enterobactin transporter membrane protein YP_851725.1 606890 R 405955 CDS YP_851726.1 117622813 4493370 608005..609255 1 NC_008563.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 609255 ybdA 4493370 ybdA Escherichia coli APEC O1 enterobactin exporter EntS YP_851726.1 608005 D 405955 CDS YP_851727.1 117622814 4493371 complement(609259..610215) 1 NC_008563.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 610215 fepB 4493371 fepB Escherichia coli APEC O1 iron-enterobactin transporter periplasmic binding protein YP_851727.1 609259 R 405955 CDS YP_851728.1 117622815 4493372 610392..611579 1 NC_008563.1 isochorismate synthase 611579 entC 4493372 entC Escherichia coli APEC O1 isochorismate synthase YP_851728.1 610392 D 405955 CDS YP_851729.1 117622816 4493373 611589..613199 1 NC_008563.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 613199 entE 4493373 entE Escherichia coli APEC O1 enterobactin synthase subunit E YP_851729.1 611589 D 405955 CDS YP_851730.1 117622817 4493374 613213..614070 1 NC_008563.1 2,3-dihydro-2,3-dihydroxybenzoate synthetase 614070 entB 4493374 entB Escherichia coli APEC O1 2,3-dihydro-2,3-dihydroxybenzoate synthetase YP_851730.1 613213 D 405955 CDS YP_851731.1 117622818 4493375 614040..614816 1 NC_008563.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 614816 entA 4493375 entA Escherichia coli APEC O1 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_851731.1 614040 D 405955 CDS YP_851732.1 117622819 4493376 614819..615232 1 NC_008563.1 hypothetical protein 615232 4493376 APECO1_1452 Escherichia coli APEC O1 hypothetical protein YP_851732.1 614819 D 405955 CDS YP_851733.1 117622820 4493377 615413..617518 1 NC_008563.1 carbon starvation protein 617518 cstA 4493377 cstA Escherichia coli APEC O1 carbon starvation protein YP_851733.1 615413 D 405955 CDS YP_851734.1 117622821 4493378 complement(617838..618926) 1 NC_008563.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 618926 ybdH 4493378 ybdH Escherichia coli APEC O1 hypothetical protein YP_851734.1 617838 R 405955 CDS YP_851735.1 117622822 4492932 618998..620206 1 NC_008563.1 catalyzes the transfer of an amino moiety; aminotransferase 620206 ybdL 4492932 ybdL Escherichia coli APEC O1 aminotransferase YP_851735.1 618998 D 405955 CDS YP_851736.1 117622823 4492933 complement(620207..620836) 1 NC_008563.1 hypothetical protein 620836 ybdM 4492933 ybdM Escherichia coli APEC O1 hypothetical protein YP_851736.1 620207 R 405955 CDS YP_851737.1 117622824 4492934 complement(620809..622029) 1 NC_008563.1 hypothetical protein 622029 ybdN 4492934 ybdN Escherichia coli APEC O1 hypothetical protein YP_851737.1 620809 R 405955 CDS YP_851738.1 117622825 4492935 complement(622176..623114) 1 NC_008563.1 transcriptional regulator YbdO 623114 ybdO 4492935 ybdO Escherichia coli APEC O1 transcriptional regulator YbdO YP_851738.1 622176 R 405955 CDS YP_851739.1 117622826 4492936 complement(623283..624089) 1 NC_008563.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 624089 dsbG 4492936 dsbG Escherichia coli APEC O1 disulfide isomerase/thiol-disulfide oxidase YP_851739.1 623283 R 405955 CDS YP_851740.1 117622827 4492937 624401..624964 1 NC_008563.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 624964 ahpC 4492937 ahpC Escherichia coli APEC O1 alkyl hydroperoxide reductase subunit C YP_851740.1 624401 D 405955 CDS YP_851741.1 117622828 4492938 625105..626700 1 NC_008563.1 alkyl hydroperoxide reductase subunit F 626700 ahpF 4492938 ahpF Escherichia coli APEC O1 alkyl hydroperoxide reductase subunit F YP_851741.1 625105 D 405955 CDS YP_851742.1 117622829 4492939 complement(626822..627283) 1 NC_008563.1 universal stress protein UspG 627283 uspG 4492939 uspG Escherichia coli APEC O1 universal stress protein UspG YP_851742.1 626822 R 405955 CDS YP_851743.1 117622830 4492940 complement(627606..628016) 1 NC_008563.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 628016 rnk 4492940 rnk Escherichia coli APEC O1 nucleoside diphosphate kinase regulator YP_851743.1 627606 R 405955 CDS YP_851744.1 117622831 4492941 complement(628246..629070) 1 NC_008563.1 ribonuclease I 629070 rna 4492941 rna Escherichia coli APEC O1 ribonuclease I YP_851744.1 628246 R 405955 CDS YP_851745.1 117622832 4492942 complement(629166..630629) 1 NC_008563.1 citrate carrier/transporter 630629 ybdS 4492942 ybdS Escherichia coli APEC O1 citrate carrier/transporter YP_851745.1 629166 R 405955 CDS YP_851746.1 117622833 4492943 complement(630680..631558) 1 NC_008563.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 631558 citG 4492943 citG Escherichia coli APEC O1 triphosphoribosyl-dephospho-CoA synthase YP_851746.1 630680 R 405955 CDS YP_851747.1 117622834 4492944 complement(631533..632084) 1 NC_008563.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 632084 citX 4492944 citX Escherichia coli APEC O1 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_851747.1 631533 R 405955 CDS YP_851748.1 117622835 4492945 complement(632088..633662) 1 NC_008563.1 citrate lyase subunit alpha 633662 citF 4492945 citF Escherichia coli APEC O1 citrate lyase subunit alpha YP_851748.1 632088 R 405955 CDS YP_851749.1 117622836 4492946 complement(633631..634554) 1 NC_008563.1 citrate lyase subunit beta 634554 citE 4492946 citE Escherichia coli APEC O1 citrate lyase subunit beta YP_851749.1 633631 R 405955 CDS YP_851750.1 117622837 4492947 complement(634847..635992) 1 NC_008563.1 citrate lyase synthetase 635992 citC 4492947 citC Escherichia coli APEC O1 citrate lyase synthetase YP_851750.1 634847 R 405955 CDS YP_851751.1 117622838 4492948 636284..637942 1 NC_008563.1 sensor kinase DpiB 637942 dpiB 4492948 dpiB Escherichia coli APEC O1 sensor kinase DpiB YP_851751.1 636284 D 405955 CDS YP_851752.1 117622839 4492949 637911..638591 1 NC_008563.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 638591 dpiA 4492949 dpiA Escherichia coli APEC O1 two-component response regulator DpiA YP_851752.1 637911 D 405955 CDS YP_851753.1 117622840 4492950 complement(638632..640017) 1 NC_008563.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 640017 dcuC 4492950 dcuC Escherichia coli APEC O1 C4-dicarboxylate transporter DcuC YP_851753.1 638632 R 405955 CDS YP_851754.1 117622841 4494290 640604..641164 1 NC_008563.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 641164 pagP 4494290 pagP Escherichia coli APEC O1 palmitoyl transferase YP_851754.1 640604 D 405955 CDS YP_851755.1 117622842 4494291 complement(641602..641985) 1 NC_008563.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 641985 crcB 4494291 crcB Escherichia coli APEC O1 camphor resistance protein CrcB YP_851755.1 641602 R 405955 CDS YP_851756.1 117622843 4494292 642075..642869 1 NC_008563.1 amidase 642869 ybeM 4494292 ybeM Escherichia coli APEC O1 amidase YP_851756.1 642075 D 405955 CDS YP_851757.1 117622844 4494293 complement(643301..644266) 1 NC_008563.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 644266 lipA 4494293 lipA Escherichia coli APEC O1 lipoyl synthase YP_851757.1 643301 R 405955 CDS YP_851758.1 117622845 4494294 complement(644485..644826) 1 NC_008563.1 hypothetical protein 644826 4494294 APECO1_1426 Escherichia coli APEC O1 hypothetical protein YP_851758.1 644485 R 405955 CDS YP_851759.1 117622846 4494295 complement(645086..645661) 1 NC_008563.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase 645661 lipB 4494295 lipB Escherichia coli APEC O1 lipoyltransferase YP_851759.1 645086 R 405955 CDS YP_851760.1 117622847 4494296 complement(645828..646091) 1 NC_008563.1 hypothetical protein 646091 4494296 APECO1_1424 Escherichia coli APEC O1 hypothetical protein YP_851760.1 645828 R 405955 CDS YP_851761.1 117622848 4494297 complement(646201..647412) 1 NC_008563.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 647412 dacA 4494297 dacA Escherichia coli APEC O1 D-alanyl-D-alanine carboxypeptidase YP_851761.1 646201 R 405955 CDS YP_851762.1 117622849 4494298 complement(647552..648889) 1 NC_008563.1 rare lipoprotein A 648889 rlpA 4494298 rlpA Escherichia coli APEC O1 rare lipoprotein A YP_851762.1 647552 R 405955 CDS YP_851763.1 117622850 4494299 complement(648652..649764) 1 NC_008563.1 cell wall shape-determining protein 649764 mrdB 4494299 mrdB Escherichia coli APEC O1 cell wall shape-determining protein YP_851763.1 648652 R 405955 CDS YP_851764.1 117622851 4494300 complement(649767..651668) 1 NC_008563.1 penicillin-binding protein 2 651668 pbpA 4494300 pbpA Escherichia coli APEC O1 penicillin-binding protein 2 YP_851764.1 649767 R 405955 CDS YP_851765.1 117622852 4494301 complement(651699..652166) 1 NC_008563.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 652166 4494301 APECO1_1419 Escherichia coli APEC O1 rRNA large subunit methyltransferase YP_851765.1 651699 R 405955 CDS YP_851766.1 117622853 4494302 652501..652791 1 NC_008563.1 hypothetical protein 652791 4494302 APECO1_1418 Escherichia coli APEC O1 hypothetical protein YP_851766.1 652501 D 405955 CDS YP_851767.1 117622854 4494303 complement(652747..653361) 1 NC_008563.1 alpha-ribazole-5'-phosphate phosphatase 653361 phpB 4494303 phpB Escherichia coli APEC O1 alpha-ribazole-5'-phosphate phosphatase YP_851767.1 652747 R 405955 CDS YP_851768.1 117622855 4494304 complement(653382..654023) 1 NC_008563.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 654023 nadD 4494304 nadD Escherichia coli APEC O1 nicotinic acid mononucleotide adenylyltransferase YP_851768.1 653382 R 405955 CDS YP_851769.1 117622856 4494305 complement(654025..655056) 1 NC_008563.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 655056 holA 4494305 holA Escherichia coli APEC O1 DNA polymerase III subunit delta YP_851769.1 654025 R 405955 CDS YP_851770.1 117622857 4494306 complement(655056..655637) 1 NC_008563.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 655637 rlpB 4494306 rlpB Escherichia coli APEC O1 LPS-assembly lipoprotein RlpB YP_851770.1 655056 R 405955 CDS YP_851771.1 117622858 4494307 complement(655652..658375) 1 NC_008563.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 658375 leuS 4494307 leuS Escherichia coli APEC O1 leucyl-tRNA synthetase YP_851771.1 655652 R 405955 CDS YP_851772.1 117622859 4494308 658469..658951 1 NC_008563.1 hypothetical protein 658951 ybeL 4494308 ybeL Escherichia coli APEC O1 hypothetical protein YP_851772.1 658469 D 405955 CDS YP_851773.1 117622860 4494309 complement(658996..659931) 1 NC_008563.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 659931 rihA 4494309 rihA Escherichia coli APEC O1 ribonucleoside hydrolase 1 YP_851773.1 658996 R 405955 CDS YP_851774.1 117622861 4492387 complement(660049..660774) 1 NC_008563.1 glutamate/aspartate ABC transporter ATP-binding protein 660774 gltL 4492387 gltL Escherichia coli APEC O1 glutamate/aspartate ABC transporter ATP-binding protein YP_851774.1 660049 R 405955 CDS YP_851775.1 117622862 4492388 complement(660774..661448) 1 NC_008563.1 glutamate/aspartate transport system permease 661448 gltK 4492388 gltK Escherichia coli APEC O1 glutamate/aspartate transport system permease YP_851775.1 660774 R 405955 CDS YP_851776.1 117622863 4492389 complement(661448..662188) 1 NC_008563.1 glutamate and aspartate transporter subunit 662188 gltJ 4492389 gltJ Escherichia coli APEC O1 glutamate and aspartate transporter subunit YP_851776.1 661448 R 405955 CDS YP_851777.1 117622864 4492390 complement(662358..663335) 1 NC_008563.1 glutamate and aspartate transporter subunit 663335 ybeJ 4492390 ybeJ Escherichia coli APEC O1 glutamate and aspartate transporter subunit YP_851777.1 662358 R 405955 CDS YP_851778.1 117622865 4492391 663720..665597 1 NC_008563.1 hypothetical protein 665597 4492391 APECO1_1407 Escherichia coli APEC O1 hypothetical protein YP_851778.1 663720 D 405955 CDS YP_851779.1 117622866 4492392 complement(665724..667265) 1 NC_008563.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 667265 lnt 4492392 lnt Escherichia coli APEC O1 apolipoprotein N-acyltransferase YP_851779.1 665724 R 405955 CDS YP_851780.1 117622867 4492393 complement(667290..668168) 1 NC_008563.1 transporter 668168 ybeX 4492393 ybeX Escherichia coli APEC O1 transporter YP_851780.1 667290 R 405955 CDS YP_851781.1 117622868 4492394 complement(668258..668725) 1 NC_008563.1 metalloprotease 668725 4492394 APECO1_1404 Escherichia coli APEC O1 metalloprotease YP_851781.1 668258 R 405955 CDS YP_851782.1 117622869 4492395 complement(668722..669801) 1 NC_008563.1 ATP-binding protein in pho regulon 669801 ybeZ 4492395 ybeZ Escherichia coli APEC O1 ATP-binding protein in pho regulon YP_851782.1 668722 R 405955 CDS YP_851783.1 117622870 4492396 complement(669915..671339) 1 NC_008563.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 671339 miaB 4492396 miaB Escherichia coli APEC O1 (dimethylallyl)adenosine tRNA methylthiotransferase YP_851783.1 669915 R 405955 CDS YP_851784.1 117622871 4492397 671485..672660 1 NC_008563.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 672660 ubiF 4492397 ubiF Escherichia coli APEC O1 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_851784.1 671485 D 405955 CDS YP_851787.1 117622874 4492400 complement(673901..675799) 1 NC_008563.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 675799 asnB 4492400 asnB Escherichia coli APEC O1 asparagine synthetase B YP_851787.1 673901 R 405955 CDS YP_851788.1 117622875 4492401 complement(675821..676573) 1 NC_008563.1 UMP phosphatase 676573 nagD 4492401 nagD Escherichia coli APEC O1 UMP phosphatase YP_851788.1 675821 R 405955 CDS YP_851789.1 117622876 4492402 complement(676621..677841) 1 NC_008563.1 transcriptional repressor of nag 677841 nagC 4492402 nagC Escherichia coli APEC O1 transcriptional repressor of nag YP_851789.1 676621 R 405955 CDS YP_851790.1 117622877 4492403 complement(677850..678998) 1 NC_008563.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 678998 nagA 4492403 nagA Escherichia coli APEC O1 N-acetylglucosamine-6-phosphate deacetylase YP_851790.1 677850 R 405955 CDS YP_851791.1 117622878 4492404 complement(679058..679858) 1 NC_008563.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 679858 nagB 4492404 nagB Escherichia coli APEC O1 glucosamine-6-phosphate deaminase YP_851791.1 679058 R 405955 CDS YP_851792.1 117622879 4492405 680191..682137 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 682137 nagE 4492405 nagE Escherichia coli APEC O1 PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_851792.1 680191 D 405955 CDS YP_851793.1 117622880 4492278 complement(682226..683752) 1 NC_008563.1 hypothetical protein 683752 4492278 APECO1_1392 Escherichia coli APEC O1 hypothetical protein YP_851793.1 682226 R 405955 CDS YP_851794.1 117622881 4492279 complement(683987..685156) 1 NC_008563.1 hypothetical protein 685156 4492279 APECO1_1391 Escherichia coli APEC O1 hypothetical protein YP_851794.1 683987 R 405955 CDS YP_851795.1 117622882 4492280 complement(685221..685742) 1 NC_008563.1 hypothetical protein 685742 4492280 APECO1_1390 Escherichia coli APEC O1 hypothetical protein YP_851795.1 685221 R 405955 CDS YP_851796.1 117622883 4492281 complement(686002..686889) 1 NC_008563.1 dihydrodipicolinate synthase 686889 4492281 APECO1_1389 Escherichia coli APEC O1 dihydrodipicolinate synthase YP_851796.1 686002 R 405955 CDS YP_851797.1 117622884 4492282 complement(686893..688050) 1 NC_008563.1 alcohol dehydrogenase 688050 4492282 APECO1_1388 Escherichia coli APEC O1 alcohol dehydrogenase YP_851797.1 686893 R 405955 CDS YP_851798.1 117622885 4492283 688214..689455 1 NC_008563.1 hypothetical protein 689455 4492283 APECO1_1387 Escherichia coli APEC O1 hypothetical protein YP_851798.1 688214 D 405955 CDS YP_851799.1 117622886 4492284 689448..690434 1 NC_008563.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 690434 pdxA 4492284 pdxA Escherichia coli APEC O1 4-hydroxythreonine-4-phosphate dehydrogenase YP_851799.1 689448 D 405955 CDS YP_851800.1 117622887 4492285 690436..691197 1 NC_008563.1 transcriptional regulator 691197 4492285 APECO1_1385 Escherichia coli APEC O1 transcriptional regulator YP_851800.1 690436 D 405955 CDS YP_851801.1 117622888 4492286 691417..693081 1 NC_008563.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 693081 glnS 4492286 glnS Escherichia coli APEC O1 glutaminyl-tRNA synthetase YP_851801.1 691417 D 405955 CDS YP_851802.1 117622889 4492287 693530..694936 1 NC_008563.1 hypothetical protein 694936 ybfM 4492287 ybfM Escherichia coli APEC O1 hypothetical protein YP_851802.1 693530 D 405955 CDS YP_851803.1 117622890 4492288 694986..695312 1 NC_008563.1 lipoprotein ybfN precursor 695312 ybfN 4492288 ybfN Escherichia coli APEC O1 lipoprotein ybfN precursor YP_851803.1 694986 D 405955 CDS YP_851804.1 117622891 4492289 complement(695396..695842) 1 NC_008563.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 695842 fur 4492289 fur Escherichia coli APEC O1 ferric uptake regulator YP_851804.1 695396 R 405955 CDS YP_851805.1 117622892 4492290 complement(696131..696778) 1 NC_008563.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 696778 fldA 4492290 fldA Escherichia coli APEC O1 flavodoxin FldA YP_851805.1 696131 R 405955 CDS YP_851806.1 117622893 4493477 complement(696801..697163) 1 NC_008563.1 LexA regulated protein 697163 ybfE 4493477 ybfE Escherichia coli APEC O1 LexA regulated protein YP_851806.1 696801 R 405955 CDS YP_851807.1 117622894 4493478 complement(697234..697998) 1 NC_008563.1 hypothetical protein 697998 ybfF 4493478 ybfF Escherichia coli APEC O1 hypothetical protein YP_851807.1 697234 R 405955 CDS YP_851808.1 117622895 4493479 698183..698728 1 NC_008563.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 698728 seqA 4493479 seqA Escherichia coli APEC O1 replication initiation regulator SeqA YP_851808.1 698183 D 405955 CDS YP_851809.1 117622896 4493480 698754..700394 1 NC_008563.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 700394 pgm 4493480 pgm Escherichia coli APEC O1 phosphoglucomutase YP_851809.1 698754 D 405955 CDS YP_851810.1 117622897 4493481 complement(700451..701770) 1 NC_008563.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 701770 potE 4493481 potE Escherichia coli APEC O1 putrescine transporter YP_851810.1 700451 R 405955 CDS YP_851811.1 117622898 4493482 complement(701767..703974) 1 NC_008563.1 ornithine decarboxylase 703974 speF 4493482 speF Escherichia coli APEC O1 ornithine decarboxylase YP_851811.1 701767 R 405955 CDS YP_851812.1 117622899 4493483 complement(704654..705331) 1 NC_008563.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 705331 kdpE 4493483 kdpE Escherichia coli APEC O1 DNA-binding transcriptional activator KdpE YP_851812.1 704654 R 405955 CDS YP_851813.1 117622900 4493484 complement(705328..708012) 1 NC_008563.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 708012 kdpD 4493484 kdpD Escherichia coli APEC O1 sensor protein KdpD YP_851813.1 705328 R 405955 CDS YP_851814.1 117622901 4493485 complement(708005..708589) 1 NC_008563.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 708589 kdpC 4493485 kdpC Escherichia coli APEC O1 potassium-transporting ATPase subunit C YP_851814.1 708005 R 405955 CDS YP_851815.1 117622902 4493486 complement(708586..710634) 1 NC_008563.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 710634 kdpB 4493486 kdpB Escherichia coli APEC O1 potassium-transporting ATPase subunit B YP_851815.1 708586 R 405955 CDS YP_851816.1 117622903 4493487 complement(710657..712426) 1 NC_008563.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 712426 kdpA 4493487 kdpA Escherichia coli APEC O1 potassium-transporting ATPase subunit A YP_851816.1 710657 R 405955 CDS YP_851817.1 117622904 4493488 713039..713548 1 NC_008563.1 hypothetical protein 713548 ybgA 4493488 ybgA Escherichia coli APEC O1 hypothetical protein YP_851817.1 713039 D 405955 CDS YP_851818.1 117622905 4493489 713545..714963 1 NC_008563.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 714963 phrB 4493489 phrB Escherichia coli APEC O1 deoxyribodipyrimidine photolyase YP_851818.1 713545 D 405955 CDS YP_851819.1 117622906 4493490 complement(715005..716486) 1 NC_008563.1 hypothetical protein 716486 ybgH 4493490 ybgH Escherichia coli APEC O1 hypothetical protein YP_851819.1 715005 R 405955 CDS YP_851820.1 117622907 4493491 716757..717500 1 NC_008563.1 hydrolase-oxidase 717500 ybgI 4493491 ybgI Escherichia coli APEC O1 hydrolase-oxidase YP_851820.1 716757 D 405955 CDS YP_851821.1 117622908 4493492 717523..718179 1 NC_008563.1 hypothetical protein 718179 ybgJ 4493492 ybgJ Escherichia coli APEC O1 hypothetical protein YP_851821.1 717523 D 405955 CDS YP_851822.1 117622909 4493493 718173..719105 1 NC_008563.1 hypothetical protein 719105 ybgK 4493493 ybgK Escherichia coli APEC O1 hypothetical protein YP_851822.1 718173 D 405955 CDS YP_851823.1 117622910 4493494 719095..719829 1 NC_008563.1 LamB/YcsF family protein 719829 ybgL 4493494 ybgL Escherichia coli APEC O1 LamB/YcsF family protein YP_851823.1 719095 D 405955 CDS YP_851824.1 117622911 4493495 719865..720656 1 NC_008563.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 720656 nei 4493495 nei Escherichia coli APEC O1 endonuclease VIII YP_851824.1 719865 D 405955 CDS YP_851825.1 117622912 4494310 complement(720653..721744) 1 NC_008563.1 transport protein AbrB 721744 abrB 4494310 abrB Escherichia coli APEC O1 transport protein AbrB YP_851825.1 720653 R 405955 CDS YP_851826.1 117622913 4494311 complement(721851..722225) 1 NC_008563.1 hypothetical protein 722225 ybgO 4494311 ybgO Escherichia coli APEC O1 hypothetical protein YP_851826.1 721851 R 405955 CDS YP_851827.1 117622914 4494312 complement(722373..723656) 1 NC_008563.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 723656 gltA 4494312 gltA Escherichia coli APEC O1 type II citrate synthase YP_851827.1 722373 R 405955 CDS YP_851828.1 117622915 4494313 724350..724754 1 NC_008563.1 succinate dehydrogenase cytochrome b556 large membrane subunit 724754 sdhC 4494313 sdhC Escherichia coli APEC O1 succinate dehydrogenase cytochrome b556 large membrane subunit YP_851828.1 724350 D 405955 CDS YP_851829.1 117622916 4494314 724748..725095 1 NC_008563.1 succinate dehydrogenase cytochrome b556 small membrane subunit 725095 sdhD 4494314 sdhD Escherichia coli APEC O1 succinate dehydrogenase cytochrome b556 small membrane subunit YP_851829.1 724748 D 405955 CDS YP_851830.1 117622917 4494315 725083..726861 1 NC_008563.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 726861 sdhA 4494315 sdhA Escherichia coli APEC O1 succinate dehydrogenase flavoprotein subunit YP_851830.1 725083 D 405955 CDS YP_851831.1 117622918 4494318 726877..727593 1 NC_008563.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 727593 sdhB 4494318 sdhB Escherichia coli APEC O1 succinate dehydrogenase iron-sulfur subunit YP_851831.1 726877 D 405955 CDS YP_851832.1 117622919 4494319 727954..730755 1 NC_008563.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 730755 sucA 4494319 sucA Escherichia coli APEC O1 2-oxoglutarate dehydrogenase E1 component YP_851832.1 727954 D 405955 CDS YP_851833.1 117622920 4494320 730770..731987 1 NC_008563.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 731987 sucB 4494320 sucB Escherichia coli APEC O1 dihydrolipoamide succinyltransferase YP_851833.1 730770 D 405955 CDS YP_851834.1 117622921 4494321 732081..733247 1 NC_008563.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 733247 sucC 4494321 sucC Escherichia coli APEC O1 succinyl-CoA synthetase subunit beta YP_851834.1 732081 D 405955 CDS YP_851835.1 117622922 4494322 733247..734116 1 NC_008563.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 734116 sucD 4494322 sucD Escherichia coli APEC O1 succinyl-CoA synthetase subunit alpha YP_851835.1 733247 D 405955 CDS YP_851836.1 117622923 4494323 734356..735471 1 NC_008563.1 hypothetical protein 735471 4494323 APECO1_1349 Escherichia coli APEC O1 hypothetical protein YP_851836.1 734356 D 405955 CDS YP_851837.1 117622924 4494324 736798..738369 1 NC_008563.1 cytochrome d terminal oxidase, subunit I 738369 cydA 4494324 cydA Escherichia coli APEC O1 cytochrome d terminal oxidase, subunit I YP_851837.1 736798 D 405955 CDS YP_851839.1 117622926 4494326 739652..739945 1 NC_008563.1 hypothetical protein 739945 4494326 APECO1_1346 Escherichia coli APEC O1 hypothetical protein YP_851839.1 739652 D 405955 CDS YP_851840.1 117622927 4494327 740095..740499 1 NC_008563.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 740499 4494327 APECO1_1345 Escherichia coli APEC O1 acyl-CoA thioester hydrolase YbgC YP_851840.1 740095 D 405955 CDS YP_851841.1 117622928 4494328 740496..741188 1 NC_008563.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 741188 tolQ 4494328 tolQ Escherichia coli APEC O1 colicin uptake protein TolQ YP_851841.1 740496 D 405955 CDS YP_851842.1 117622929 4494329 741192..741620 1 NC_008563.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 741620 4494329 APECO1_1343 Escherichia coli APEC O1 colicin uptake protein TolR YP_851842.1 741192 D 405955 CDS YP_851843.1 117622930 4495308 741685..742935 1 NC_008563.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 742935 tolA 4495308 tolA Escherichia coli APEC O1 cell envelope integrity inner membrane protein TolA YP_851843.1 741685 D 405955 CDS YP_851844.1 117622931 4495309 743065..744360 1 NC_008563.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 744360 tolB 4495309 tolB Escherichia coli APEC O1 translocation protein TolB YP_851844.1 743065 D 405955 CDS YP_851845.1 117622932 4495310 744395..744916 1 NC_008563.1 peptidoglycan-associated outer membrane lipoprotein 744916 pal 4495310 pal Escherichia coli APEC O1 peptidoglycan-associated outer membrane lipoprotein YP_851845.1 744395 D 405955 CDS YP_851846.1 117622933 4495311 744926..745717 1 NC_008563.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 745717 ybgF 4495311 ybgF Escherichia coli APEC O1 tol-pal system protein YbgF YP_851846.1 744926 D 405955 CDS YP_851847.1 117622934 4495312 746863..747906 1 NC_008563.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 747906 nadA 4495312 nadA Escherichia coli APEC O1 quinolinate synthetase YP_851847.1 746863 D 405955 CDS YP_851848.1 117622935 4495313 747944..748663 1 NC_008563.1 hypothetical protein 748663 pnuC 4495313 pnuC Escherichia coli APEC O1 hypothetical protein YP_851848.1 747944 D 405955 CDS YP_851849.1 117622936 4495314 complement(748660..749601) 1 NC_008563.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 749601 ybgR 4495314 ybgR Escherichia coli APEC O1 zinc transporter ZitB YP_851849.1 748660 R 405955 CDS YP_851850.1 117622937 4495315 complement(749715..750095) 1 NC_008563.1 hypothetical protein 750095 ybgS 4495315 ybgS Escherichia coli APEC O1 hypothetical protein YP_851850.1 749715 R 405955 CDS YP_851851.1 117622938 4495316 750411..751463 1 NC_008563.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 751463 aroG 4495316 aroG Escherichia coli APEC O1 phospho-2-dehydro-3-deoxyheptonate aldolase YP_851851.1 750411 D 405955 CDS YP_851852.1 117622939 4495317 complement(751630..752382) 1 NC_008563.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 752382 gpmA 4495317 gpmA Escherichia coli APEC O1 phosphoglyceromutase YP_851852.1 751630 R 405955 CDS YP_851853.1 117622940 4495318 complement(752585..753625) 1 NC_008563.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 753625 galM 4495318 galM Escherichia coli APEC O1 aldose 1-epimerase YP_851853.1 752585 R 405955 CDS YP_851854.1 117622941 4495319 complement(753619..754767) 1 NC_008563.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 754767 galK 4495319 galK Escherichia coli APEC O1 galactokinase YP_851854.1 753619 R 405955 CDS YP_851855.1 117622942 4495320 complement(754771..755817) 1 NC_008563.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 755817 galT 4495320 galT Escherichia coli APEC O1 galactose-1-phosphate uridylyltransferase YP_851855.1 754771 R 405955 CDS YP_851856.1 117622943 4495321 complement(755827..756885) 1 NC_008563.1 UDP-galactose-4-epimerase 756885 galE 4495321 galE Escherichia coli APEC O1 UDP-galactose-4-epimerase YP_851856.1 755827 R 405955 CDS YP_851857.2 162317584 4495322 complement(757106..758578) 1 NC_008563.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 758578 modF 4495322 modF Escherichia coli APEC O1 molybdenum transport ATP-binding protein ModF YP_851857.2 757106 R 405955 CDS YP_851858.1 117622945 4495323 complement(758646..759434) 1 NC_008563.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 759434 modE 4495323 modE Escherichia coli APEC O1 DNA-binding transcriptional regulator ModE YP_851858.1 758646 R 405955 CDS YP_851859.1 117622946 4495324 759879..760652 1 NC_008563.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 760652 modA 4495324 modA Escherichia coli APEC O1 molybdate transporter periplasmic protein YP_851859.1 759879 D 405955 CDS YP_851860.1 117622947 4495325 760652..761341 1 NC_008563.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 761341 modB 4495325 modB Escherichia coli APEC O1 molybdate ABC transporter permease YP_851860.1 760652 D 405955 CDS YP_851861.1 117622948 4495326 761344..762402 1 NC_008563.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 762402 modC 4495326 modC Escherichia coli APEC O1 molybdate transporter ATP-binding protein YP_851861.1 761344 D 405955 CDS YP_851862.1 117622949 4493438 complement(762403..763317) 1 NC_008563.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 763317 yghA 4493438 yghA Escherichia coli APEC O1 phosphotransferase YP_851862.1 762403 R 405955 CDS YP_851863.1 117622950 4493439 763376..764371 1 NC_008563.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 764371 ybhE 4493439 ybhE Escherichia coli APEC O1 6-phosphogluconolactonase YP_851863.1 763376 D 405955 CDS YP_851864.1 117622951 4493440 complement(764412..765428) 1 NC_008563.1 DNA-binding transcriptional regulator 765428 ybhD 4493440 ybhD Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851864.1 764412 R 405955 CDS YP_851865.1 117622952 4493441 765549..766601 1 NC_008563.1 hypothetical protein 766601 4493441 APECO1_1320 Escherichia coli APEC O1 hypothetical protein YP_851865.1 765549 D 405955 CDS YP_851866.1 117622953 4493442 766677..768110 1 NC_008563.1 hypothetical protein 768110 ybhI 4493442 ybhI Escherichia coli APEC O1 hypothetical protein YP_851866.1 766677 D 405955 CDS YP_851867.1 117622954 4493443 768269..770554 1 NC_008563.1 hypothetical protein 770554 ybhJ 4493443 ybhJ Escherichia coli APEC O1 hypothetical protein YP_851867.1 768269 D 405955 CDS YP_851868.1 117622955 4493444 complement(770695..771978) 1 NC_008563.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase 771978 ybhC 4493444 ybhC Escherichia coli APEC O1 pectinesterase YP_851868.1 770695 R 405955 CDS YP_851869.1 117622956 4493445 complement(772130..772606) 1 NC_008563.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 772606 ybhB 4493445 ybhB Escherichia coli APEC O1 kinase inhibitor protein YP_851869.1 772130 R 405955 CDS YP_851870.1 117622957 4493446 complement(772665..773954) 1 NC_008563.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 773954 bioA 4493446 bioA Escherichia coli APEC O1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_851870.1 772665 R 405955 CDS YP_851871.1 117622958 4493447 774042..775082 1 NC_008563.1 biotin synthase 775082 bioB 4493447 bioB Escherichia coli APEC O1 biotin synthase YP_851871.1 774042 D 405955 CDS YP_851872.1 117622959 4493448 775079..776233 1 NC_008563.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 776233 bioF 4493448 bioF Escherichia coli APEC O1 8-amino-7-oxononanoate synthase YP_851872.1 775079 D 405955 CDS YP_851873.2 229775975 4493449 776220..776975 1 NC_008563.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 776975 bioC 4493449 bioC Escherichia coli APEC O1 biotin biosynthesis protein BioC YP_851873.2 776220 D 405955 CDS YP_851874.1 117622961 4493450 776968..777645 1 NC_008563.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 777645 bioD 4493450 bioD Escherichia coli APEC O1 dithiobiotin synthetase YP_851874.1 776968 D 405955 CDS YP_851875.1 117622962 4493451 778224..780245 1 NC_008563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 780245 uvrB 4493451 uvrB Escherichia coli APEC O1 excinuclease ABC subunit B YP_851875.1 778224 D 405955 CDS YP_851876.1 117622963 4493452 complement(780283..781191) 1 NC_008563.1 hypothetical protein 781191 ybhK 4493452 ybhK Escherichia coli APEC O1 hypothetical protein YP_851876.1 780283 R 405955 CDS YP_851877.1 117622964 4493453 781513..782577 1 NC_008563.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 782577 moaA 4493453 moaA Escherichia coli APEC O1 molybdenum cofactor biosynthesis protein A YP_851877.1 781513 D 405955 CDS YP_851878.1 117622965 4493454 782599..783111 1 NC_008563.1 molybdopterin biosynthesis, protein B 783111 moaB 4493454 moaB Escherichia coli APEC O1 molybdopterin biosynthesis, protein B YP_851878.1 782599 D 405955 CDS YP_851879.1 117622966 4493455 783114..783599 1 NC_008563.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 783599 moaC 4493455 moaC Escherichia coli APEC O1 molybdenum cofactor biosynthesis protein MoaC YP_851879.1 783114 D 405955 CDS YP_851880.1 117622967 4493456 783839..784291 1 NC_008563.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 784291 moaE 4493456 moaE Escherichia coli APEC O1 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_851880.1 783839 D 405955 CDS YP_851881.1 117622968 4493457 784428..785132 1 NC_008563.1 hypothetical protein 785132 ybhL 4493457 ybhL Escherichia coli APEC O1 hypothetical protein YP_851881.1 784428 D 405955 CDS YP_851882.1 117622969 4492329 785311..786051 1 NC_008563.1 hypothetical protein 786051 ybhM 4492329 ybhM Escherichia coli APEC O1 hypothetical protein YP_851882.1 785311 D 405955 CDS YP_851883.1 117622970 4492330 complement(786087..787043) 1 NC_008563.1 hypothetical protein 787043 ybhN 4492330 ybhN Escherichia coli APEC O1 hypothetical protein YP_851883.1 786087 R 405955 CDS YP_851884.1 117622971 4492331 complement(787043..788284) 1 NC_008563.1 cardiolipin synthase 2 788284 ybhO 4492331 ybhO Escherichia coli APEC O1 cardiolipin synthase 2 YP_851884.1 787043 R 405955 CDS YP_851885.1 117622972 4492332 complement(788281..789042) 1 NC_008563.1 metal-dependent hydrolase 789042 4492332 APECO1_1300 Escherichia coli APEC O1 metal-dependent hydrolase YP_851885.1 788281 R 405955 CDS YP_851886.1 117622973 4492333 789175..789585 1 NC_008563.1 hypothetical protein 789585 ybhQ 4492333 ybhQ Escherichia coli APEC O1 hypothetical protein YP_851886.1 789175 D 405955 CDS YP_851887.1 117622974 4492334 complement(789547..790653) 1 NC_008563.1 hypothetical protein 790653 ybhR 4492334 ybhR Escherichia coli APEC O1 hypothetical protein YP_851887.1 789547 R 405955 CDS YP_851888.1 117622975 4492335 complement(790664..791797) 1 NC_008563.1 hypothetical protein 791797 ybhS 4492335 ybhS Escherichia coli APEC O1 hypothetical protein YP_851888.1 790664 R 405955 CDS YP_851889.1 117622976 4492336 complement(791790..793541) 1 NC_008563.1 ABC transporter 793541 ybhF 4492336 ybhF Escherichia coli APEC O1 ABC transporter YP_851889.1 791790 R 405955 CDS YP_851890.1 117622977 4492337 complement(793519..794517) 1 NC_008563.1 hypothetical protein 794517 ybhG 4492337 ybhG Escherichia coli APEC O1 hypothetical protein YP_851890.1 793519 R 405955 CDS YP_851891.1 117622978 4492338 complement(794517..795200) 1 NC_008563.1 DNA-binding transcriptional regulator 795200 ybiH 4492338 ybiH Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_851891.1 794517 R 405955 CDS YP_851892.1 117622979 4492339 795417..796778 1 NC_008563.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 796778 rhlE 4492339 rhlE Escherichia coli APEC O1 ATP-dependent RNA helicase RhlE YP_851892.1 795417 D 405955 CDS YP_851893.1 117622980 4492340 complement(797011..797316) 1 NC_008563.1 hypothetical protein 797316 4492340 APECO1_1292 Escherichia coli APEC O1 hypothetical protein YP_851893.1 797011 R 405955 CDS YP_851894.1 117622981 4492341 797315..799465 1 NC_008563.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 799465 dinG 4492341 dinG Escherichia coli APEC O1 ATP-dependent DNA helicase DinG YP_851894.1 797315 D 405955 CDS YP_851895.1 117622982 4492342 799493..800455 1 NC_008563.1 glycosyl transferase family protein 800455 ybiB 4492342 ybiB Escherichia coli APEC O1 glycosyl transferase family protein YP_851895.1 799493 D 405955 CDS YP_851896.1 117622983 4492343 800596..801681 1 NC_008563.1 hypothetical protein 801681 ybiC 4492343 ybiC Escherichia coli APEC O1 hypothetical protein YP_851896.1 800596 D 405955 CDS YP_851898.1 117622985 4492345 complement(802774..803487) 1 NC_008563.1 hydroxylase 803487 ybiX 4492345 ybiX Escherichia coli APEC O1 hydroxylase YP_851898.1 802774 R 405955 CDS YP_851899.1 117622986 4492346 complement(803667..805949) 1 NC_008563.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 805949 ybiL 4492346 ybiL Escherichia coli APEC O1 catecholate siderophore receptor Fiu YP_851899.1 803667 R 405955 CDS YP_851900.1 117622987 4492347 complement(806214..806621) 1 NC_008563.1 hypothetical protein 806621 ybiM 4492347 ybiM Escherichia coli APEC O1 hypothetical protein YP_851900.1 806214 R 405955 CDS YP_851901.1 117622988 4494605 806660..807676 1 NC_008563.1 SAM-dependent methyltransferase 807676 ybiN 4494605 ybiN Escherichia coli APEC O1 SAM-dependent methyltransferase YP_851901.1 806660 D 405955 CDS YP_851902.1 117622989 4494608 complement(807673..809898) 1 NC_008563.1 hypothetical protein 809898 ybiO 4494608 ybiO Escherichia coli APEC O1 hypothetical protein YP_851902.1 807673 R 405955 CDS YP_851903.1 117622990 4494609 complement(810015..810737) 1 NC_008563.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 810737 glnQ 4494609 glnQ Escherichia coli APEC O1 glutamine ABC transporter ATP-binding protein YP_851903.1 810015 R 405955 CDS YP_851904.1 117622991 4494610 complement(810734..811393) 1 NC_008563.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 811393 glnP 4494610 glnP Escherichia coli APEC O1 glutamine ABC transporter permease YP_851904.1 810734 R 405955 CDS YP_851905.1 117622992 4494611 complement(811532..812278) 1 NC_008563.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 812278 glnH 4494611 glnH Escherichia coli APEC O1 glutamine ABC transporter periplasmic protein YP_851905.1 811532 R 405955 CDS YP_851906.1 117622993 4494612 complement(812682..813278) 1 NC_008563.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 813278 dps 4494612 dps Escherichia coli APEC O1 DNA starvation/stationary phase protection protein Dps YP_851906.1 812682 R 405955 CDS YP_851907.1 117622994 4494613 complement(813484..814383) 1 NC_008563.1 threonine and homoserine efflux system 814383 ybiF 4494613 ybiF Escherichia coli APEC O1 threonine and homoserine efflux system YP_851907.1 813484 R 405955 CDS YP_851908.1 117622995 4494614 814718..815239 1 NC_008563.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 815239 ompX 4494614 ompX Escherichia coli APEC O1 outer membrane protein X YP_851908.1 814718 D 405955 CDS YP_851909.1 117622996 4494615 complement(815289..816872) 1 NC_008563.1 hypothetical protein 816872 ybiP 4494615 ybiP Escherichia coli APEC O1 hypothetical protein YP_851909.1 815289 R 405955 CDS YP_851910.1 117622997 4494616 817458..817925 1 NC_008563.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 817925 mntR 4494616 mntR Escherichia coli APEC O1 manganese transport regulator MntR YP_851910.1 817458 D 405955 CDS YP_851911.1 117622998 4494617 817922..819040 1 NC_008563.1 hypothetical protein 819040 ybiR 4494617 ybiR Escherichia coli APEC O1 hypothetical protein YP_851911.1 817922 D 405955 CDS YP_851912.1 117622999 4494618 complement(819098..820018) 1 NC_008563.1 hypothetical protein 820018 ybiS 4494618 ybiS Escherichia coli APEC O1 hypothetical protein YP_851912.1 819098 R 405955 CDS YP_851913.1 117623000 4494619 820237..821829 1 NC_008563.1 ATP-binding component of a transport system 821829 ybiT 4494619 ybiT Escherichia coli APEC O1 ATP-binding component of a transport system YP_851913.1 820237 D 405955 CDS YP_851914.1 117623001 4494620 complement(822029..822844) 1 NC_008563.1 hypothetical protein 822844 ybiV 4494620 ybiV Escherichia coli APEC O1 hypothetical protein YP_851914.1 822029 R 405955 CDS YP_851915.1 117623002 4494621 complement(822990..825422) 1 NC_008563.1 formate acetyltransferase 3 825422 ybiW 4494621 ybiW Escherichia coli APEC O1 formate acetyltransferase 3 YP_851915.1 822990 R 405955 CDS YP_851916.1 117623003 4494622 complement(825428..826327) 1 NC_008563.1 pyruvate formate lyase activating enzyme 826327 ybiY 4494622 ybiY Escherichia coli APEC O1 pyruvate formate lyase activating enzyme YP_851916.1 825428 R 405955 CDS YP_851917.2 162317583 4494658 826458..827120 1 NC_008563.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 827120 4494658 APECO1_1268 Escherichia coli APEC O1 fructose-6-phosphate aldolase YP_851917.2 826458 D 405955 CDS YP_851918.1 117623005 4494659 complement(827196..827945) 1 NC_008563.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 827945 moeB 4494659 moeB Escherichia coli APEC O1 molybdopterin biosynthesis protein MoeB YP_851918.1 827196 R 405955 CDS YP_851919.1 117623006 4494660 complement(827945..829180) 1 NC_008563.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 829180 moeA 4494660 moeA Escherichia coli APEC O1 molybdopterin biosynthesis protein MoeA YP_851919.1 827945 R 405955 CDS YP_851920.1 117623007 4494661 829384..830349 1 NC_008563.1 L-asparaginase 830349 iaaA 4494661 iaaA Escherichia coli APEC O1 L-asparaginase YP_851920.1 829384 D 405955 CDS YP_851921.1 117623008 4494662 830228..832207 1 NC_008563.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 832207 yliA 4494662 yliA Escherichia coli APEC O1 glutathione transporter ATP-binding protein YP_851921.1 830228 D 405955 CDS YP_851922.1 117623009 4494663 831819..832937 1 NC_008563.1 peptide transporter periplasmic-binding protein 832937 yliB 4494663 yliB Escherichia coli APEC O1 peptide transporter periplasmic-binding protein YP_851922.1 831819 D 405955 CDS YP_851923.1 117623010 4494664 832921..833766 1 NC_008563.1 peptide transporter periplasmic-binding protein 833766 yliB 4494664 yliB Escherichia coli APEC O1 peptide transporter periplasmic-binding protein YP_851923.1 832921 D 405955 CDS YP_851924.1 117623011 4494665 833784..834704 1 NC_008563.1 peptide transporter membrane protein 834704 yliC 4494665 yliC Escherichia coli APEC O1 peptide transporter membrane protein YP_851924.1 833784 D 405955 CDS YP_851925.1 117623012 4494666 834707..835618 1 NC_008563.1 peptide transporter membrane protein 835618 yliD 4494666 yliD Escherichia coli APEC O1 peptide transporter membrane protein YP_851925.1 834707 D 405955 CDS YP_851926.1 117623013 4494667 835795..838143 1 NC_008563.1 hypothetical protein 838143 yliE 4494667 yliE Escherichia coli APEC O1 hypothetical protein YP_851926.1 835795 D 405955 CDS YP_851927.1 117623014 4494668 838151..839479 1 NC_008563.1 diguanylate cyclase 839479 yliF 4494668 yliF Escherichia coli APEC O1 diguanylate cyclase YP_851927.1 838151 D 405955 CDS YP_851928.1 117623015 4494669 complement(839526..840851) 1 NC_008563.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 840851 rimO 4494669 rimO Escherichia coli APEC O1 ribosomal protein S12 methylthiotransferase YP_851928.1 839526 R 405955 CDS YP_851929.1 117623016 4494670 841064..841447 1 NC_008563.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 841447 bssR 4494670 bssR Escherichia coli APEC O1 biofilm formation regulatory protein BssR YP_851929.1 841064 D 405955 CDS YP_851930.1 117623017 4494673 841558..842673 1 NC_008563.1 dehydrogenase 842673 yliI 4494673 yliI Escherichia coli APEC O1 dehydrogenase YP_851930.1 841558 D 405955 CDS YP_851931.1 117623018 4494674 complement(842670..843302) 1 NC_008563.1 glutathione S-transferase 843302 yliJ 4494674 yliJ Escherichia coli APEC O1 glutathione S-transferase YP_851931.1 842670 R 405955 CDS YP_851932.1 117623019 4494675 843522..844745 1 NC_008563.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 844745 dacC 4494675 dacC Escherichia coli APEC O1 D-alanyl-D-alanine carboxypeptidase YP_851932.1 843522 D 405955 CDS YP_851933.1 117623020 4494676 complement(844792..845550) 1 NC_008563.1 DNA-binding transcriptional repressor DeoR 845550 deoR 4494676 deoR Escherichia coli APEC O1 DNA-binding transcriptional repressor DeoR YP_851933.1 844792 R 405955 CDS YP_851934.1 117623021 4492952 complement(845608..846204) 1 NC_008563.1 undecaprenyl pyrophosphate phosphatase 846204 ybjG 4492952 ybjG Escherichia coli APEC O1 undecaprenyl pyrophosphate phosphatase YP_851934.1 845608 R 405955 CDS YP_851935.1 117623022 4492953 846489..847721 1 NC_008563.1 proton motive force efflux pump 847721 cmr 4492953 cmr Escherichia coli APEC O1 proton motive force efflux pump YP_851935.1 846489 D 405955 CDS YP_851936.1 117623023 4492954 complement(847762..848028) 1 NC_008563.1 hypothetical protein 848028 ybjH 4492954 ybjH Escherichia coli APEC O1 hypothetical protein YP_851936.1 847762 R 405955 CDS YP_851937.1 117623024 4492955 complement(848113..848928) 1 NC_008563.1 hypothetical protein 848928 ybjI 4492955 ybjI Escherichia coli APEC O1 hypothetical protein YP_851937.1 848113 R 405955 CDS YP_851938.1 117623025 4492956 complement(848928..850136) 1 NC_008563.1 DEOR-type transcriptional regulator 850136 ybjJ 4492956 ybjJ Escherichia coli APEC O1 DEOR-type transcriptional regulator YP_851938.1 848928 R 405955 CDS YP_851939.1 117623026 4492957 850220..850756 1 NC_008563.1 DEOR-type transcriptional regulator 850756 ybjK 4492957 ybjK Escherichia coli APEC O1 DEOR-type transcriptional regulator YP_851939.1 850220 D 405955 CDS YP_851940.1 117623027 4492958 complement(850931..852616) 1 NC_008563.1 hypothetical protein 852616 4492958 APECO1_1246 Escherichia coli APEC O1 hypothetical protein YP_851940.1 850931 R 405955 CDS YP_851941.1 117623028 4492959 852886..853263 1 NC_008563.1 hypothetical protein 853263 ybjM 4492959 ybjM Escherichia coli APEC O1 hypothetical protein YP_851941.1 852886 D 405955 CDS YP_851942.1 117623029 4492960 complement(853293..853565) 1 NC_008563.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 853565 grxA 4492960 grxA Escherichia coli APEC O1 glutaredoxin YP_851942.1 853293 R 405955 CDS YP_851943.1 117623030 4492961 853710..853997 1 NC_008563.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 853997 ybjC 4492961 ybjC Escherichia coli APEC O1 hypothetical protein YP_851943.1 853710 D 405955 CDS YP_851944.1 117623031 4492962 853981..854703 1 NC_008563.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 854703 nfsA 4492962 nfsA Escherichia coli APEC O1 nitroreductase A YP_851944.1 853981 D 405955 CDS YP_851945.1 117623032 4492963 854764..855666 1 NC_008563.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 855666 rimK 4492963 rimK Escherichia coli APEC O1 ribosomal protein S6 modification protein YP_851945.1 854764 D 405955 CDS YP_851946.1 117623033 4492964 855754..856230 1 NC_008563.1 hypothetical protein 856230 ybjN 4492964 ybjN Escherichia coli APEC O1 hypothetical protein YP_851946.1 855754 D 405955 CDS YP_851947.1 117623034 4492965 856436..857692 1 NC_008563.1 putrescine ABC transporter periplasmic-binding protein 857692 potF 4492965 potF Escherichia coli APEC O1 putrescine ABC transporter periplasmic-binding protein YP_851947.1 856436 D 405955 CDS YP_851948.1 117623035 4492966 857706..858920 1 NC_008563.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 858920 potG 4492966 potG Escherichia coli APEC O1 putrescine ABC transporter ATP-binding protein YP_851948.1 857706 D 405955 CDS YP_851949.1 117623036 4492967 858930..859883 1 NC_008563.1 putrescine ABC transporter membrane protein 859883 potH 4492967 potH Escherichia coli APEC O1 putrescine ABC transporter membrane protein YP_851949.1 858930 D 405955 CDS YP_851950.1 117623037 4492968 859838..860725 1 NC_008563.1 putrescine ABC transporter membrane protein 860725 potI 4492968 potI Escherichia coli APEC O1 putrescine ABC transporter membrane protein YP_851950.1 859838 D 405955 CDS YP_851951.1 117623038 4492969 860785..861273 1 NC_008563.1 hypothetical protein 861273 4492969 APECO1_1235 Escherichia coli APEC O1 hypothetical protein YP_851951.1 860785 D 405955 CDS YP_851952.1 117623039 4492970 861314..862441 1 NC_008563.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 862441 rumB 4492970 rumB Escherichia coli APEC O1 23S rRNA methyluridine methyltransferase YP_851952.1 861314 D 405955 CDS YP_851953.1 117623040 4493302 complement(862470..863252) 1 NC_008563.1 arginine/ornithine ABC transporter substrate-binding protein 863252 artJ 4493302 artJ Escherichia coli APEC O1 arginine/ornithine ABC transporter substrate-binding protein YP_851953.1 862470 R 405955 CDS YP_851954.1 117623041 4493303 complement(863427..864095) 1 NC_008563.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 864095 artM 4493303 artM Escherichia coli APEC O1 arginine transporter permease subunit ArtM YP_851954.1 863427 R 405955 CDS YP_851955.1 117623042 4493304 complement(864095..864811) 1 NC_008563.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 864811 artQ 4493304 artQ Escherichia coli APEC O1 arginine transporter permease subunit ArtQ YP_851955.1 864095 R 405955 CDS YP_851956.1 117623043 4493305 complement(864818..865549) 1 NC_008563.1 arginine transporter subunit 865549 artI 4493305 artI Escherichia coli APEC O1 arginine transporter subunit YP_851956.1 864818 R 405955 CDS YP_851957.1 117623044 4493306 complement(865567..866301) 1 NC_008563.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 866301 artP 4493306 artP Escherichia coli APEC O1 arginine transporter ATP-binding subunit YP_851957.1 865567 R 405955 CDS YP_851958.1 117623045 4493307 complement(866513..866899) 1 NC_008563.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 866899 ybjP 4493307 ybjP Escherichia coli APEC O1 lipoprotein YP_851958.1 866513 R 405955 CDS YP_851959.1 117623046 4493308 867153..867476 1 NC_008563.1 hypothetical protein 867476 4493308 APECO1_1227 Escherichia coli APEC O1 hypothetical protein YP_851959.1 867153 D 405955 CDS YP_851960.1 117623047 4493309 867473..868303 1 NC_008563.1 N-acetylmuramoyl-L-alanine amidase YbjR 868303 ybjR 4493309 ybjR Escherichia coli APEC O1 N-acetylmuramoyl-L-alanine amidase YbjR YP_851960.1 867473 D 405955 CDS YP_851961.1 117623048 4493310 complement(869412..870905) 1 NC_008563.1 hypothetical protein 870905 ybjS 4493310 ybjS Escherichia coli APEC O1 hypothetical protein YP_851961.1 869412 R 405955 CDS YP_851962.1 117623049 4493311 complement(870853..871854) 1 NC_008563.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 871854 ybjU 4493311 ybjU Escherichia coli APEC O1 L-threonine aldolase YP_851962.1 870853 R 405955 CDS YP_851963.1 117623050 4493312 complement(871891..873609) 1 NC_008563.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 873609 poxB 4493312 poxB Escherichia coli APEC O1 pyruvate dehydrogenase YP_851963.1 871891 R 405955 CDS YP_851964.1 117623051 4493313 complement(873742..874710) 1 NC_008563.1 HCP oxidoreductase 874710 hcr 4493313 hcr Escherichia coli APEC O1 HCP oxidoreductase YP_851964.1 873742 R 405955 CDS YP_851965.1 117623052 4493314 complement(874722..876380) 1 NC_008563.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 876380 hcp 4493314 hcp Escherichia coli APEC O1 hydroxylamine reductase YP_851965.1 874722 R 405955 CDS YP_851966.1 117623053 4493315 complement(876518..877462) 1 NC_008563.1 hypothetical protein 877462 ybjE 4493315 ybjE Escherichia coli APEC O1 hypothetical protein YP_851966.1 876518 R 405955 CDS YP_851967.1 117623054 4493316 complement(877738..878439) 1 NC_008563.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 878439 aqpZ 4493316 aqpZ Escherichia coli APEC O1 aquaporin Z YP_851967.1 877738 R 405955 CDS YP_851968.1 117623055 4493317 878859..880517 1 NC_008563.1 hypothetical protein 880517 ybjD 4493317 ybjD Escherichia coli APEC O1 hypothetical protein YP_851968.1 878859 D 405955 CDS YP_851969.1 117623056 4493318 complement(880514..881506) 1 NC_008563.1 hypothetical protein 881506 ybjX 4493318 ybjX Escherichia coli APEC O1 hypothetical protein YP_851969.1 880514 R 405955 CDS YP_851970.1 117623057 4493319 881621..882736 1 NC_008563.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 882736 macA 4493319 macA Escherichia coli APEC O1 macrolide transporter subunit MacA YP_851970.1 881621 D 405955 CDS YP_851971.1 117623058 4493320 882733..884679 1 NC_008563.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 884679 ybjZ 4493320 ybjZ Escherichia coli APEC O1 macrolide transporter ATP-binding /permease YP_851971.1 882733 D 405955 CDS YP_851972.1 117623059 4491889 885299..885619 1 NC_008563.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 885619 clpS 4491889 clpS Escherichia coli APEC O1 ATP-dependent Clp protease adaptor protein ClpS YP_851972.1 885299 D 405955 CDS YP_851973.1 117623060 4491890 885644..887926 1 NC_008563.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 887926 clpA 4491890 clpA Escherichia coli APEC O1 ATP-dependent Clp protease ATP-binding subunit YP_851973.1 885644 D 405955 CDS YP_851974.1 117623061 4491891 complement(888044..888316) 1 NC_008563.1 hypothetical protein 888316 4491891 APECO1_1212 Escherichia coli APEC O1 hypothetical protein YP_851974.1 888044 R 405955 CDS YP_851975.1 117623062 4491892 888633..889622 1 NC_008563.1 hypothetical protein 889622 4491892 APECO1_1211 Escherichia coli APEC O1 hypothetical protein YP_851975.1 888633 D 405955 CDS YP_851976.1 117623063 4491893 889619..892852 1 NC_008563.1 hypothetical protein 892852 4491893 APECO1_1210 Escherichia coli APEC O1 hypothetical protein YP_851976.1 889619 D 405955 CDS YP_851977.1 117623064 4491894 893182..894489 1 NC_008563.1 hypothetical protein 894489 4491894 APECO1_1209 Escherichia coli APEC O1 hypothetical protein YP_851977.1 893182 D 405955 CDS YP_851978.1 117623065 4491895 894768..895409 1 NC_008563.1 hypothetical protein 895409 4491895 APECO1_1208 Escherichia coli APEC O1 hypothetical protein YP_851978.1 894768 D 405955 CDS YP_851979.1 117623066 4491896 895420..896421 1 NC_008563.1 hypothetical protein 896421 4491896 APECO1_1207 Escherichia coli APEC O1 hypothetical protein YP_851979.1 895420 D 405955 CDS YP_851980.1 117623067 4491897 896390..896986 1 NC_008563.1 hypothetical protein 896986 4491897 APECO1_1206 Escherichia coli APEC O1 hypothetical protein YP_851980.1 896390 D 405955 CDS YP_851981.1 117623068 4491898 897554..897874 1 NC_008563.1 hypothetical protein 897874 4491898 APECO1_1205 Escherichia coli APEC O1 hypothetical protein YP_851981.1 897554 D 405955 CDS YP_851982.1 117623069 4491899 complement(898531..899235) 1 NC_008563.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 899235 aat 4491899 aat Escherichia coli APEC O1 leucyl/phenylalanyl-tRNA--protein transferase YP_851982.1 898531 R 405955 CDS YP_851983.1 117623070 4491900 complement(899277..900998) 1 NC_008563.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 900998 cydC 4491900 cydC Escherichia coli APEC O1 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_851983.1 899277 R 405955 CDS YP_851984.1 117623071 4491901 complement(900999..902765) 1 NC_008563.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 902765 cydD 4491901 cydD Escherichia coli APEC O1 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_851984.1 900999 R 405955 CDS YP_851985.1 117623072 4491902 complement(902888..903958) 1 NC_008563.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 903958 trxB 4491902 trxB Escherichia coli APEC O1 thioredoxin reductase YP_851985.1 902888 R 405955 CDS YP_851986.1 117623073 4491903 904343..904891 1 NC_008563.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 904891 lrp 4491903 lrp Escherichia coli APEC O1 leucine-responsive transcriptional regulator YP_851986.1 904343 D 405955 CDS YP_851987.1 117623074 4491904 905137..909069 1 NC_008563.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 909069 ftsK 4491904 ftsK Escherichia coli APEC O1 DNA translocase FtsK YP_851987.1 905137 D 405955 CDS YP_851988.1 117623075 4491905 909225..909839 1 NC_008563.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 909839 lolA 4491905 lolA Escherichia coli APEC O1 outer-membrane lipoprotein carrier protein YP_851988.1 909225 D 405955 CDS YP_851989.1 117623076 4491906 909850..911193 1 NC_008563.1 recombination factor protein RarA 911193 ycaJ 4491906 ycaJ Escherichia coli APEC O1 recombination factor protein RarA YP_851989.1 909850 D 405955 CDS YP_851990.1 117623077 4491907 911284..912576 1 NC_008563.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 912576 serS 4491907 serS Escherichia coli APEC O1 seryl-tRNA synthetase YP_851990.1 911284 D 405955 CDS YP_851991.1 117623078 4491908 912815..915259 1 NC_008563.1 anaerobic dimethyl sulfoxide reductase subunit A 915259 dmsA 4491908 dmsA Escherichia coli APEC O1 anaerobic dimethyl sulfoxide reductase subunit A YP_851991.1 912815 D 405955 CDS YP_851992.1 117623079 4491401 915270..915887 1 NC_008563.1 anaerobic dimethyl sulfoxide reductase subunit B 915887 dmsB 4491401 dmsB Escherichia coli APEC O1 anaerobic dimethyl sulfoxide reductase subunit B YP_851992.1 915270 D 405955 CDS YP_851993.1 117623080 4491402 915826..916752 1 NC_008563.1 anaerobic dimethyl sulfoxide reductase subunit C 916752 dmsC 4491402 dmsC Escherichia coli APEC O1 anaerobic dimethyl sulfoxide reductase subunit C YP_851993.1 915826 D 405955 CDS YP_851994.1 117623081 4491403 complement(916788..917513) 1 NC_008563.1 hypothetical protein 917513 ycaC 4491403 ycaC Escherichia coli APEC O1 hypothetical protein YP_851994.1 916788 R 405955 CDS YP_851995.1 117623082 4491404 917728..918876 1 NC_008563.1 MFS family transporter protein 918876 ycaD 4491404 ycaD Escherichia coli APEC O1 MFS family transporter protein YP_851995.1 917728 D 405955 CDS YP_851996.1 117623083 4491405 complement(918973..919770) 1 NC_008563.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 919770 pflA 4491405 pflA Escherichia coli APEC O1 pyruvate formate lyase-activating enzyme 1 YP_851996.1 918973 R 405955 CDS YP_851997.1 117623084 4491406 complement(919802..920797) 1 NC_008563.1 integrase 920797 4491406 APECO1_1189 Escherichia coli APEC O1 integrase YP_851997.1 919802 R 405955 CDS YP_851998.1 117623085 4491407 complement(920891..921202) 1 NC_008563.1 Phage protein C 921202 c 4491407 c Escherichia coli APEC O1 Phage protein C YP_851998.1 920891 R 405955 CDS YP_851999.1 117623086 4491408 921307..921663 1 NC_008563.1 phage-associated; Cox protein 921663 cox 4491408 cox Escherichia coli APEC O1 Cox protein YP_851999.1 921307 D 405955 CDS YP_852000.1 117623087 4491409 921835..922341 1 NC_008563.1 phage-associated; hypothetical protein 922341 gpB 4491409 gpB Escherichia coli APEC O1 hypothetical protein YP_852000.1 921835 D 405955 CDS YP_852001.1 117623088 4491410 922629..922928 1 NC_008563.1 phage-associated; hypothetical protein 922928 4491410 APECO1_4462 Escherichia coli APEC O1 hypothetical protein YP_852001.1 922629 D 405955 CDS YP_852002.1 117623089 4491411 923152..923427 1 NC_008563.1 phage-associated; relication initiation protein 923427 4491411 APECO1_4463 Escherichia coli APEC O1 relication initiation protein YP_852002.1 923152 D 405955 CDS YP_852003.1 117623090 4491412 923417..925708 1 NC_008563.1 phage replication initiation protein 925708 4491412 APECO1_4464 Escherichia coli APEC O1 phage replication initiation protein YP_852003.1 923417 D 405955 CDS YP_852004.1 117623091 4491413 complement(925932..928148) 1 NC_008563.1 hypothetical protein 928148 4491413 APECO1_4465 Escherichia coli APEC O1 hypothetical protein YP_852004.1 925932 R 405955 CDS YP_852005.1 117623092 4491414 complement(928652..929686) 1 NC_008563.1 phage capsid protein 929686 4491414 APECO1_4466 Escherichia coli APEC O1 phage capsid protein YP_852005.1 928652 R 405955 CDS YP_852006.1 117623093 4491415 complement(929686..931458) 1 NC_008563.1 phage terminase 931458 4491415 APECO1_4467 Escherichia coli APEC O1 phage terminase YP_852006.1 929686 R 405955 CDS YP_852007.1 117623094 4491416 931566..932486 1 NC_008563.1 phage capsid scaffolding protein 932486 4491416 APECO1_4468 Escherichia coli APEC O1 phage capsid scaffolding protein YP_852007.1 931566 D 405955 CDS YP_852008.1 117623095 4491417 932545..933618 1 NC_008563.1 phage-associated; major capsid protein 933618 4491417 APECO1_4469 Escherichia coli APEC O1 major capsid protein YP_852008.1 932545 D 405955 CDS YP_852009.1 117623096 4491418 933622..934365 1 NC_008563.1 small terminase subunit 934365 4491418 APECO1_4470 Escherichia coli APEC O1 small terminase subunit YP_852009.1 933622 D 405955 CDS YP_852010.1 117623097 4491419 934405..934974 1 NC_008563.1 capsid completion protein 934974 4491419 APECO1_4471 Escherichia coli APEC O1 capsid completion protein YP_852010.1 934405 D 405955 CDS YP_852011.1 117623098 4492816 935181..935462 1 NC_008563.1 phage lysis holin 935462 4492816 APECO1_4472 Escherichia coli APEC O1 phage lysis holin YP_852011.1 935181 D 405955 CDS YP_852012.1 117623099 4492817 935462..935959 1 NC_008563.1 phage lysin 935959 4492817 APECO1_4473 Escherichia coli APEC O1 phage lysin YP_852012.1 935462 D 405955 CDS YP_852013.1 117623100 4492818 935974..936399 1 NC_008563.1 phage-associated; LysA protein 936399 4492818 APECO1_4474 Escherichia coli APEC O1 LysA protein YP_852013.1 935974 D 405955 CDS YP_852014.1 117623101 4492819 936387..936812 1 NC_008563.1 phage-associated; LysB protein 936812 4492819 APECO1_4475 Escherichia coli APEC O1 LysB protein YP_852014.1 936387 D 405955 CDS YP_852015.1 117623102 4492820 936920..937387 1 NC_008563.1 phage-associated; tail protein 937387 4492820 APECO1_4476 Escherichia coli APEC O1 tail protein YP_852015.1 936920 D 405955 CDS YP_852016.1 117623103 4492821 937380..937832 1 NC_008563.1 phage-associated; tail protein 937832 4492821 APECO1_4477 Escherichia coli APEC O1 tail protein YP_852016.1 937380 D 405955 CDS YP_852017.1 117623104 4492822 937899..938534 1 NC_008563.1 phage baseplate protein 938534 4492822 APECO1_4478 Escherichia coli APEC O1 phage baseplate protein YP_852017.1 937899 D 405955 CDS YP_852018.1 117623105 4492823 938531..938878 1 NC_008563.1 phage baseplate protein 938878 4492823 APECO1_4479 Escherichia coli APEC O1 phage baseplate protein YP_852018.1 938531 D 405955 CDS YP_852019.1 117623106 4492824 938883..939791 1 NC_008563.1 phage-associated; baseplate assembly protein 939791 4492824 APECO1_4480 Escherichia coli APEC O1 baseplate assembly protein YP_852019.1 938883 D 405955 CDS YP_852020.1 117623107 4492825 939784..940314 1 NC_008563.1 tail protein 940314 4492825 APECO1_4481 Escherichia coli APEC O1 tail protein YP_852020.1 939784 D 405955 CDS YP_852021.1 117623108 4492826 940325..942334 1 NC_008563.1 phage-associated; tail fiber protein 942334 4492826 APECO1_4482 Escherichia coli APEC O1 tail fiber protein YP_852021.1 940325 D 405955 CDS YP_852022.1 117623109 4492827 942338..942865 1 NC_008563.1 phage-associated; tail fiber assembly protein 942865 4492827 APECO1_44822 Escherichia coli APEC O1 tail fiber assembly protein YP_852022.1 942338 D 405955 CDS YP_852023.1 117623110 4492828 complement(943266..944852) 1 NC_008563.1 phage-associated protein 944852 funZ 4492828 funZ Escherichia coli APEC O1 phage-associated protein YP_852023.1 943266 R 405955 CDS YP_852024.1 117623111 4492830 945243..945659 1 NC_008563.1 Phage tail sheath protein; hypothetical protein 945659 gpF1 4492830 gpF1 Escherichia coli APEC O1 hypothetical protein YP_852024.1 945243 D 405955 CDS YP_852025.1 117623112 4492831 945800..946996 1 NC_008563.1 transposase for ISEc12; hypothetical protein 946996 tnpA 4492831 tnpA Escherichia coli APEC O1 hypothetical protein YP_852025.1 945800 D 405955 CDS YP_852026.1 117623113 4492832 947354..948103 1 NC_008563.1 ISEc12 ATP-binding protein; hypothetical protein 948103 tnpA 4492832 tnpA Escherichia coli APEC O1 hypothetical protein YP_852026.1 947354 D 405955 CDS YP_852027.1 117623114 4492833 948154..949020 1 NC_008563.1 Phage tail sheath protein; hypothetical protein 949020 gpF1 4492833 gpF1 Escherichia coli APEC O1 hypothetical protein YP_852027.1 948154 D 405955 CDS YP_852028.1 117623115 4492834 949033..949551 1 NC_008563.1 Phage tail tube protein FII; hypothetical protein 949551 gpFII 4492834 gpFII Escherichia coli APEC O1 hypothetical protein YP_852028.1 949033 D 405955 CDS YP_852029.1 117623116 4492835 complement(949563..949952) 1 NC_008563.1 hypothetical protein 949952 4492835 APECO1_10 Escherichia coli APEC O1 hypothetical protein YP_852029.1 949563 R 405955 CDS YP_852030.1 117623117 4494330 950028..952475 1 NC_008563.1 Phage-related tail protein; hypothetical protein 952475 gpT 4494330 gpT Escherichia coli APEC O1 hypothetical protein YP_852030.1 950028 D 405955 CDS YP_852031.1 117623118 4494331 952490..952969 1 NC_008563.1 essential tail protein; gpU phage protein 952969 gpU 4494331 gpU Escherichia coli APEC O1 gpU phage protein YP_852031.1 952490 D 405955 CDS YP_852032.1 117623119 4494332 952969..954132 1 NC_008563.1 essential tail protein; hypothetical protein 954132 gpD 4494332 gpD Escherichia coli APEC O1 hypothetical protein YP_852032.1 952969 D 405955 CDS YP_852033.1 117623120 4494333 954178..954432 1 NC_008563.1 Phage transcriptional activator; in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 954432 ogr 4494333 ogr Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_852033.1 954178 D 405955 CDS YP_852034.1 117623121 4494334 complement(954751..957033) 1 NC_008563.1 pyruvate formate lyase I; protein PflB 957033 pflB 4494334 pflB Escherichia coli APEC O1 protein PflB YP_852034.1 954751 R 405955 CDS YP_852035.1 117623122 4494335 complement(957088..958284) 1 NC_008563.1 Degradation of small molecules: carbon compounds; formate transporter 958284 focA 4494335 focA Escherichia coli APEC O1 formate transporter YP_852035.1 957088 R 405955 CDS YP_852036.1 117623123 4494336 complement(958351..960120) 1 NC_008563.1 hypothetical protein 960120 ycaO 4494336 ycaO Escherichia coli APEC O1 hypothetical protein YP_852036.1 958351 R 405955 CDS YP_852037.1 117623124 4494337 960241..960933 1 NC_008563.1 hypothetical protein 960933 ycaP 4494337 ycaP Escherichia coli APEC O1 hypothetical protein YP_852037.1 960241 D 405955 CDS YP_852038.1 117623125 4494338 961132..962220 1 NC_008563.1 3-phosphoserine/phosphohydroxythreonine aminotransferase; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 962220 serC 4494338 serC Escherichia coli APEC O1 phosphoserine aminotransferase YP_852038.1 961132 D 405955 CDS YP_852039.1 117623126 4494339 962291..963574 1 NC_008563.1 5-enolpyruvylshikimate-3-phosphate synthetase; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 963574 aroA 4494339 aroA Escherichia coli APEC O1 3-phosphoshikimate 1-carboxyvinyltransferase YP_852039.1 962291 D 405955 CDS YP_852040.1 117623127 4494340 963735..964508 1 NC_008563.1 predicted peptidase with chaperone function; hypothetical protein 964508 ycaL 4494340 ycaL Escherichia coli APEC O1 hypothetical protein YP_852040.1 963735 D 405955 CDS YP_852041.1 117623128 4494341 964681..965364 1 NC_008563.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 965364 cmk 4494341 cmk Escherichia coli APEC O1 cytidylate kinase YP_852041.1 964681 D 405955 CDS YP_852042.1 117623129 4494342 965475..967148 1 NC_008563.1 30S ribosomal subunit protein S1; in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 967148 rpsA 4494342 rpsA Escherichia coli APEC O1 30S ribosomal protein S1 YP_852042.1 965475 D 405955 CDS YP_852043.1 117623130 4494343 complement(967317..967625) 1 NC_008563.1 hypothetical protein 967625 4494343 APECO1_24 Escherichia coli APEC O1 hypothetical protein YP_852043.1 967317 R 405955 CDS YP_852044.1 117623131 4494344 967798..969663 1 NC_008563.1 conserved inner membrane protein; hypothetical protein 969663 ycaI 4494344 ycaI Escherichia coli APEC O1 hypothetical protein YP_852044.1 967798 D 405955 CDS YP_852045.1 117623132 4494345 970093..971841 1 NC_008563.1 probable transport ATP-binding protein MsbA; involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 971841 msbA 4494345 msbA Escherichia coli APEC O1 lipid transporter ATP-binding/permease YP_852045.1 970093 D 405955 CDS YP_852046.1 117623133 4494346 971838..972824 1 NC_008563.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 972824 lpxK 4494346 lpxK Escherichia coli APEC O1 tetraacyldisaccharide 4'-kinase YP_852046.1 971838 D 405955 CDS YP_852047.1 117623134 4494347 972861..974093 1 NC_008563.1 hypothetical protein 974093 ycaQ 4494347 ycaQ Escherichia coli APEC O1 hypothetical protein YP_852047.1 972861 D 405955 CDS YP_852048.1 117623135 4494348 complement(974150..974419) 1 NC_008563.1 hypothetical protein 974419 4494348 APECO1_29 Escherichia coli APEC O1 hypothetical protein YP_852048.1 974150 R 405955 CDS YP_852049.1 117623136 4491498 974324..975070 1 NC_008563.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 975070 kdsB 4491498 kdsB Escherichia coli APEC O1 3-deoxy-manno-octulosonate cytidylyltransferase YP_852049.1 974324 D 405955 CDS YP_852050.1 117623137 4491499 975224..976117 1 NC_008563.1 hypothetical protein 976117 ycbJ 4491499 ycbJ Escherichia coli APEC O1 hypothetical protein YP_852050.1 975224 D 405955 CDS YP_852051.1 117623138 4491500 complement(976094..976873) 1 NC_008563.1 hypothetical protein 976873 ycbC 4491500 ycbC Escherichia coli APEC O1 hypothetical protein YP_852051.1 976094 R 405955 CDS YP_852052.1 117623139 4491501 976997..977794 1 NC_008563.1 predicted S-adenosyl-L-methionine-dependent methyltransferase; involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 977794 smtA 4491501 smtA Escherichia coli APEC O1 metallothionein SmtA YP_852052.1 976997 D 405955 CDS YP_852053.1 117623140 4491502 977791..979113 1 NC_008563.1 Ca2+-binding protein involved in chromosome partitioning; acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 979113 mukF 4491502 mukF Escherichia coli APEC O1 condesin subunit F YP_852053.1 977791 D 405955 CDS YP_852054.1 117623141 4491503 979067..979798 1 NC_008563.1 protein involved in chromosome partitioning; acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 979798 mukE 4491503 mukE Escherichia coli APEC O1 condesin subunit E YP_852054.1 979067 D 405955 CDS YP_852055.1 117623142 4491504 979798..984258 1 NC_008563.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 984258 mukB 4491504 mukB Escherichia coli APEC O1 cell division protein MukB YP_852055.1 979798 D 405955 CDS YP_852056.1 117623143 4491505 984519..986366 1 NC_008563.1 predicted carboxypeptidase; hypothetical protein 986366 ycbB 4491505 ycbB Escherichia coli APEC O1 hypothetical protein YP_852056.1 984519 D 405955 CDS YP_852057.1 117623144 4491506 986547..987095 1 NC_008563.1 hypothetical protein 987095 ycbK 4491506 ycbK Escherichia coli APEC O1 hypothetical protein YP_852057.1 986547 D 405955 CDS YP_852058.1 117623145 4491507 987122..987769 1 NC_008563.1 hypothetical protein 987769 ycbL 4491507 ycbL Escherichia coli APEC O1 hypothetical protein YP_852058.1 987122 D 405955 CDS YP_852059.1 117623146 4491508 complement(987819..989009) 1 NC_008563.1 aspartate aminotransferase, PLP-dependent; catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 989009 aspC 4491508 aspC Escherichia coli APEC O1 aromatic amino acid aminotransferase YP_852059.1 987819 R 405955 CDS YP_852060.1 117623147 4491509 complement(989194..990282) 1 NC_008563.1 outer membrane porin 1a (Ia;b;F); outer membrane porin F; 1a; Ia; b; outer membrane protein F 990282 ompF 4491509 ompF Escherichia coli APEC O1 outer membrane protein F YP_852060.1 989194 R 405955 CDS YP_852061.2 162317582 4491510 complement(990884..992284) 1 NC_008563.1 asparagine tRNA synthetase; catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 992284 asnC 4491510 asnC Escherichia coli APEC O1 asparaginyl-tRNA synthetase YP_852061.2 990884 R 405955 CDS YP_852062.1 117623149 4491511 complement(992453..993703) 1 NC_008563.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 993703 pncB 4491511 pncB Escherichia coli APEC O1 nicotinate phosphoribosyltransferase YP_852062.1 992453 R 405955 CDS YP_852063.1 117623150 4491512 993921..996533 1 NC_008563.1 aminopeptidase N 996533 pepN 4491512 pepN Escherichia coli APEC O1 aminopeptidase N YP_852063.1 993921 D 405955 CDS YP_852064.1 117623151 4491513 complement(996728..997495) 1 NC_008563.1 alkanesulfonate transporter subunit; part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 997495 ssuB 4491513 ssuB Escherichia coli APEC O1 aliphatic sulfonates transport ATP-binding subunit YP_852064.1 996728 R 405955 CDS YP_852065.1 117623152 4491514 complement(997492..998286) 1 NC_008563.1 alkanesulfonate transporter subunit; part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 998286 ssuC 4491514 ssuC Escherichia coli APEC O1 alkanesulfonate transporter permease YP_852065.1 997492 R 405955 CDS YP_852066.1 117623153 4491515 complement(998295..999440) 1 NC_008563.1 alkanesulfonate monooxygenase, FMNH(2)-dependent; catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 999440 ssuD 4491515 ssuD Escherichia coli APEC O1 alkanesulfonate monooxygenase YP_852066.1 998295 R 405955 CDS YP_852067.1 117623154 4491516 complement(999437..1000438) 1 NC_008563.1 alkanesulfonate transporter subunit; part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1000438 ssuA 4491516 ssuA Escherichia coli APEC O1 alkanesulfonate transporter substrate-binding subunit YP_852067.1 999437 R 405955 CDS YP_852068.1 117623155 4491517 complement(1000389..1000964) 1 NC_008563.1 NAD(P)H-dependent FMN reductase 1000964 ssuE 4491517 ssuE Escherichia coli APEC O1 NAD(P)H-dependent FMN reductase YP_852068.1 1000389 R 405955 CDS YP_852069.1 117623156 4493773 1001201..1002211 1 NC_008563.1 dihydro-orotate oxidase, FMN-linked; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1002211 pyrD 4493773 pyrD Escherichia coli APEC O1 dihydroorotate dehydrogenase 2 YP_852069.1 1001201 D 405955 CDS YP_852070.1 117623157 4493774 1002349..1002927 1 NC_008563.1 hypothetical protein 1002927 ycbW 4493774 ycbW Escherichia coli APEC O1 hypothetical protein YP_852070.1 1002349 D 405955 CDS YP_852071.1 117623158 4493775 complement(1002924..1004033) 1 NC_008563.1 predicted 2Fe-2S cluster-containing protein; hypothetical protein 1004033 ycbX 4493775 ycbX Escherichia coli APEC O1 hypothetical protein YP_852071.1 1002924 R 405955 CDS YP_852072.1 117623159 4493776 1004131..1006239 1 NC_008563.1 predicted methyltransferase; catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1006239 rlmL 4493776 rlmL Escherichia coli APEC O1 23S rRNA m(2)G2445 methyltransferase YP_852072.1 1004131 D 405955 CDS YP_852073.1 117623160 4493777 1006251..1008158 1 NC_008563.1 ABC transporter ATP-binding protein uup; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1008158 uup 4493777 uup Escherichia coli APEC O1 ABC transporter ATPase YP_852073.1 1006251 D 405955 CDS YP_852074.1 117623161 4493778 1008288..1009541 1 NC_008563.1 paraquat-inducible protein A 1009541 pqiA 4493778 pqiA Escherichia coli APEC O1 paraquat-inducible protein A YP_852074.1 1008288 D 405955 CDS YP_852075.1 117623162 4493779 1009528..1011186 1 NC_008563.1 paraquat-inducible protein B 1011186 pqiB 4493779 pqiB Escherichia coli APEC O1 paraquat-inducible protein B YP_852075.1 1009528 D 405955 CDS YP_852076.1 117623163 4493780 1011183..1011746 1 NC_008563.1 hypothetical protein 1011746 4493780 APECO1_58 Escherichia coli APEC O1 hypothetical protein YP_852076.1 1011183 D 405955 CDS YP_852077.1 117623164 4493781 complement(1012239..1012955) 1 NC_008563.1 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1012955 fabA 4493781 fabA Escherichia coli APEC O1 3-hydroxydecanoyl-ACP dehydratase YP_852077.1 1012239 R 405955 CDS YP_852078.1 117623165 4493782 complement(1012826..1014412) 1 NC_008563.1 predicted peptidase; hypothetical protein 1014412 ycbZ 4493782 ycbZ Escherichia coli APEC O1 hypothetical protein YP_852078.1 1012826 R 405955 CDS YP_852079.1 117623166 4493783 1014772..1015224 1 NC_008563.1 hypothetical protein 1015224 ycbG 4493783 ycbG Escherichia coli APEC O1 hypothetical protein YP_852079.1 1014772 D 405955 CDS YP_852080.1 117623167 4493784 complement(1015302..1016414) 1 NC_008563.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1016414 ompA 4493784 ompA Escherichia coli APEC O1 outer membrane protein A YP_852080.1 1015302 R 405955 CDS YP_852081.1 117623168 4493785 complement(1016698..1017207) 1 NC_008563.1 SOS cell division inhibitor; suppressor of lon; inhibits cell division and ftsZ ring formation; SOS cell division inhibitor 1017207 sulA 4493785 sulA Escherichia coli APEC O1 SOS cell division inhibitor YP_852081.1 1016698 R 405955 CDS YP_852082.1 117623169 4493786 1017426..1018055 1 NC_008563.1 hypothetical protein 1018055 yccR 4493786 yccR Escherichia coli APEC O1 hypothetical protein YP_852082.1 1017426 D 405955 CDS YP_852083.1 117623170 4493787 complement(1018018..1020180) 1 NC_008563.1 predicted inner membrane protein of unknown function; hypothetical protein 1020180 yccS 4493787 yccS Escherichia coli APEC O1 hypothetical protein YP_852083.1 1018018 R 405955 CDS YP_852084.1 117623171 4493788 complement(1020190..1020636) 1 NC_008563.1 hypothetical protein 1020636 yccF 4493788 yccF Escherichia coli APEC O1 hypothetical protein YP_852084.1 1020190 R 405955 CDS YP_852085.1 117623172 4493789 1020666..1022813 1 NC_008563.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1022813 helD 4493789 helD Escherichia coli APEC O1 DNA helicase IV YP_852085.1 1020666 D 405955 CDS YP_852086.1 117623173 4493790 complement(1022845..1023312) 1 NC_008563.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1023312 mgsA 4493790 mgsA Escherichia coli APEC O1 methylglyoxal synthase YP_852086.1 1022845 R 405955 CDS YP_852087.1 117623174 4493791 complement(1023399..1024061) 1 NC_008563.1 hypothetical protein 1024061 4493791 APECO1_69 Escherichia coli APEC O1 hypothetical protein YP_852087.1 1023399 R 405955 CDS YP_852088.1 117623175 4494643 1024180..1024647 1 NC_008563.1 hypothetical protein 1024647 4494643 APECO1_70 Escherichia coli APEC O1 hypothetical protein YP_852088.1 1024180 D 405955 CDS YP_852089.1 117623176 4494644 complement(1024692..1025060) 1 NC_008563.1 heat shock protein HspQ 1025060 4494644 APECO1_71 Escherichia coli APEC O1 heat shock protein HspQ YP_852089.1 1024692 R 405955 CDS YP_852090.1 117623177 4494645 complement(1025067..1026257) 1 NC_008563.1 hypothetical protein 1026257 yccW 4494645 yccW Escherichia coli APEC O1 hypothetical protein YP_852090.1 1025067 R 405955 CDS YP_852091.1 117623178 4494646 1026139..1026630 1 NC_008563.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1026630 yccX 4494646 yccX Escherichia coli APEC O1 acylphosphatase YP_852091.1 1026139 D 405955 CDS YP_852092.1 117623179 4494647 complement(1026627..1026956) 1 NC_008563.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1026956 yccK 4494647 yccK Escherichia coli APEC O1 sulfur transfer protein TusE YP_852092.1 1026627 R 405955 CDS YP_852093.1 117623180 4494648 complement(1027048..1027707) 1 NC_008563.1 hypothetical protein 1027707 yccA 4494648 yccA Escherichia coli APEC O1 hypothetical protein YP_852093.1 1027048 R 405955 CDS YP_852094.1 117623181 4494649 1028401..1029546 1 NC_008563.1 hydrogenase 1, small subunit 1029546 hyaA 4494649 hyaA Escherichia coli APEC O1 hydrogenase 1, small subunit YP_852094.1 1028401 D 405955 CDS YP_852095.1 117623182 4494650 1029543..1031336 1 NC_008563.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1031336 hyaB 4494650 hyaB Escherichia coli APEC O1 hydrogenase 1 large subunit YP_852095.1 1029543 D 405955 CDS YP_852096.1 117623183 4494651 1031355..1032062 1 NC_008563.1 enzyme; Energy metabolism, carbon: Aerobic respiration; hydrogenase 1 b-type cytochrome subunit 1032062 hyaC 4494651 hyaC Escherichia coli APEC O1 hydrogenase 1 b-type cytochrome subunit YP_852096.1 1031355 D 405955 CDS YP_852097.1 117623184 4494652 1032059..1032646 1 NC_008563.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1032646 hyaD 4494652 hyaD Escherichia coli APEC O1 hydrogenase 1 maturation protease YP_852097.1 1032059 D 405955 CDS YP_852098.1 117623185 4494653 1032643..1033041 1 NC_008563.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1033041 hyaE 4494653 hyaE Escherichia coli APEC O1 hydrogenase-1 operon protein HyaE YP_852098.1 1032643 D 405955 CDS YP_852099.1 117623186 4494654 1032978..1033895 1 NC_008563.1 hydrogenase-1 operon protein HyaF 1033895 hyaF 4494654 hyaF Escherichia coli APEC O1 hydrogenase-1 operon protein HyaF YP_852099.1 1032978 D 405955 CDS YP_852100.1 117623187 4494655 1034023..1035573 1 NC_008563.1 cytochrome bd-II oxidase subunit I 1035573 appC 4494655 appC Escherichia coli APEC O1 cytochrome bd-II oxidase subunit I YP_852100.1 1034023 D 405955 CDS YP_852101.1 117623188 4494656 1035585..1036721 1 NC_008563.1 cytochrome bd-II oxidase subunit II 1036721 appB 4494656 appB Escherichia coli APEC O1 cytochrome bd-II oxidase subunit II YP_852101.1 1035585 D 405955 CDS YP_852102.1 117623189 4494657 1036876..1038216 1 NC_008563.1 phosphoanhydride phosphorylase 1038216 appA 4494657 appA Escherichia coli APEC O1 phosphoanhydride phosphorylase YP_852102.1 1036876 D 405955 CDS YP_852103.1 117623190 4494468 complement(1039530..1040603) 1 NC_008563.1 ferredoxin; electron transport protein YccM 1040603 yccM 4494468 yccM Escherichia coli APEC O1 electron transport protein YccM YP_852103.1 1039530 R 405955 CDS YP_852104.1 117623191 4494469 complement(1040686..1043418) 1 NC_008563.1 Histidine kinase; Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1043418 torS 4494469 torS Escherichia coli APEC O1 hybrid sensory histidine kinase TorS YP_852104.1 1040686 R 405955 CDS YP_852105.1 117623192 4494470 1043501..1044529 1 NC_008563.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1044529 torT 4494470 torT Escherichia coli APEC O1 TMAO reductase system periplasmic protein TorT YP_852105.1 1043501 D 405955 CDS YP_852106.1 117623193 4494471 complement(1044502..1045194) 1 NC_008563.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1045194 torR 4494471 torR Escherichia coli APEC O1 DNA-binding transcriptional regulator TorR YP_852106.1 1044502 R 405955 CDS YP_852107.1 117623194 4494472 1045324..1046496 1 NC_008563.1 cytochrome c-type protein TorC 1046496 torC 4494472 torC Escherichia coli APEC O1 cytochrome c-type protein TorC YP_852107.1 1045324 D 405955 CDS YP_852108.1 117623195 4494473 1046496..1049042 1 NC_008563.1 trimethylamine-N-oxide reductase 1 1049042 torA 4494473 torA Escherichia coli APEC O1 trimethylamine-N-oxide reductase 1 YP_852108.1 1046496 D 405955 CDS YP_852109.1 117623196 4494474 1049006..1049638 1 NC_008563.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1049638 torD 4494474 torD Escherichia coli APEC O1 chaperone protein TorD YP_852109.1 1049006 D 405955 CDS YP_852110.1 117623197 4494475 complement(1049994..1050299) 1 NC_008563.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1050299 yccD 4494475 yccD Escherichia coli APEC O1 chaperone-modulator protein CbpM YP_852110.1 1049994 R 405955 CDS YP_852111.1 117623198 4494476 complement(1050299..1051219) 1 NC_008563.1 DnaJ homolog that functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1051219 cbpA 4494476 cbpA Escherichia coli APEC O1 curved DNA-binding protein CbpA YP_852111.1 1050299 R 405955 CDS YP_852112.1 117623199 4494477 1051754..1052995 1 NC_008563.1 glucose-1-phosphatase/inositol phosphatase 1052995 agp 4494477 agp Escherichia coli APEC O1 glucose-1-phosphatase/inositol phosphatase YP_852112.1 1051754 D 405955 CDS YP_852113.1 117623200 4494478 complement(1053281..1053877) 1 NC_008563.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1053877 wrbA 4494478 wrbA Escherichia coli APEC O1 TrpR binding protein WrbA YP_852113.1 1053281 R 405955 CDS YP_852114.1 117623201 4494479 complement(1054506..1055201) 1 NC_008563.1 transporter 1055201 ycdG 4494479 ycdG Escherichia coli APEC O1 transporter YP_852114.1 1054506 R 405955 CDS YP_852115.1 117623202 4494480 complement(1055198..1055794) 1 NC_008563.1 hypothetical protein 1055794 4494480 APECO1_97 Escherichia coli APEC O1 hypothetical protein YP_852115.1 1055198 R 405955 CDS YP_852116.1 117623203 4494481 complement(1055749..1056324) 1 NC_008563.1 oxidoreductase, flavin:NADH component 1056324 ycdH 4494481 ycdH Escherichia coli APEC O1 oxidoreductase, flavin:NADH component YP_852116.1 1055749 R 405955 CDS YP_852117.1 117623204 4494482 complement(1056254..1056844) 1 NC_008563.1 hypothetical protein 1056844 ycdI 4494482 ycdI Escherichia coli APEC O1 hypothetical protein YP_852117.1 1056254 R 405955 CDS YP_852118.1 117623205 4494483 complement(1056854..1057654) 1 NC_008563.1 hydrolase 1057654 rarA 4494483 rarA Escherichia coli APEC O1 hydrolase YP_852118.1 1056854 R 405955 CDS YP_852119.1 117623206 4494484 complement(1057662..1058048) 1 NC_008563.1 hypothetical protein 1058048 ycdK 4494484 ycdK Escherichia coli APEC O1 hypothetical protein YP_852119.1 1057662 R 405955 CDS YP_852120.1 117623207 4494485 complement(1058060..1058794) 1 NC_008563.1 hypothetical protein 1058794 4494485 APECO1_102 Escherichia coli APEC O1 hypothetical protein YP_852120.1 1058060 R 405955 CDS YP_852121.1 117623208 4494486 complement(1058752..1059900) 1 NC_008563.1 monooxygenase YcdM 1059900 ycdM 4494486 ycdM Escherichia coli APEC O1 monooxygenase YcdM YP_852121.1 1058752 R 405955 CDS YP_852122.1 117623209 4495210 1060130..1060768 1 NC_008563.1 transcriptional regulator YcdC 1060768 ycdC 4495210 ycdC Escherichia coli APEC O1 transcriptional regulator YcdC YP_852122.1 1060130 D 405955 CDS YP_852123.1 117623210 4495211 complement(1060808..1064770) 1 NC_008563.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1064770 putA 4495211 putA Escherichia coli APEC O1 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_852123.1 1060808 R 405955 CDS YP_852124.1 117623211 4495212 1065193..1066701 1 NC_008563.1 proline:sodium symporter 1066701 putP 4495212 putP Escherichia coli APEC O1 proline:sodium symporter YP_852124.1 1065193 D 405955 CDS YP_852125.1 117623212 4495213 1066912..1067751 1 NC_008563.1 hypothetical protein 1067751 ycdN 4495213 ycdN Escherichia coli APEC O1 hypothetical protein YP_852125.1 1066912 D 405955 CDS YP_852126.1 117623213 4495214 1067809..1068936 1 NC_008563.1 hypothetical protein 1068936 ycdO 4495214 ycdO Escherichia coli APEC O1 hypothetical protein YP_852126.1 1067809 D 405955 CDS YP_852127.1 117623214 4495215 1068942..1070213 1 NC_008563.1 hypothetical protein 1070213 ycdB 4495215 ycdB Escherichia coli APEC O1 hypothetical protein YP_852127.1 1068942 D 405955 CDS YP_852128.1 117623215 4495217 1070704..1071627 1 NC_008563.1 hypothetical protein 1071627 phoH 4495217 phoH Escherichia coli APEC O1 hypothetical protein YP_852128.1 1070704 D 405955 CDS YP_852129.1 117623216 4495218 complement(1071677..1072090) 1 NC_008563.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1072090 pgaD 4495218 pgaD Escherichia coli APEC O1 PGA biosynthesis protein YP_852129.1 1071677 R 405955 CDS YP_852130.1 117623217 4495219 complement(1072092..1073417) 1 NC_008563.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1073417 ycdQ 4495219 ycdQ Escherichia coli APEC O1 N-glycosyltransferase YP_852130.1 1072092 R 405955 CDS YP_852131.1 117623218 4495220 complement(1073410..1075428) 1 NC_008563.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1075428 pgaB 4495220 pgaB Escherichia coli APEC O1 outer membrane N-deacetylase YP_852131.1 1073410 R 405955 CDS YP_852132.1 117623219 4495221 complement(1075437..1077860) 1 NC_008563.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1077860 pgaA 4495221 pgaA Escherichia coli APEC O1 outer membrane protein PgaA YP_852132.1 1075437 R 405955 CDS YP_852133.1 117623220 4495222 1078448..1079815 1 NC_008563.1 diguanylate cyclase 1079815 ycdT 4495222 ycdT Escherichia coli APEC O1 diguanylate cyclase YP_852133.1 1078448 D 405955 CDS YP_852135.1 117623222 4495224 1080202..1081179 1 NC_008563.1 dehydrogenase 1081179 ycdW 4495224 ycdW Escherichia coli APEC O1 dehydrogenase YP_852135.1 1080202 D 405955 CDS YP_852136.1 117623223 4495225 1081234..1081971 1 NC_008563.1 hydrolase 1081971 ycdX 4495225 ycdX Escherichia coli APEC O1 hydrolase YP_852136.1 1081234 D 405955 CDS YP_852137.1 117623224 4495226 1081995..1082549 1 NC_008563.1 hypothetical protein 1082549 ycdY 4495226 ycdY Escherichia coli APEC O1 hypothetical protein YP_852137.1 1081995 D 405955 CDS YP_852138.1 117623225 4495227 1082603..1083142 1 NC_008563.1 hypothetical protein 1083142 ycdZ 4495227 ycdZ Escherichia coli APEC O1 hypothetical protein YP_852138.1 1082603 D 405955 CDS YP_852139.1 117623226 4495228 complement(1083207..1084040) 1 NC_008563.1 assembly /transport component in curli production 1084040 csgG 4495228 csgG Escherichia coli APEC O1 assembly /transport component in curli production YP_852139.1 1083207 R 405955 CDS YP_852140.1 117623227 4495229 complement(1084067..1084483) 1 NC_008563.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1084483 csgF 4495229 csgF Escherichia coli APEC O1 curli assembly protein CsgF YP_852140.1 1084067 R 405955 CDS YP_852141.1 117623228 4495846 complement(1084508..1084897) 1 NC_008563.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1084897 csgE 4495846 csgE Escherichia coli APEC O1 curli assembly protein CsgE YP_852141.1 1084508 R 405955 CDS YP_852142.1 117623229 4495847 complement(1084902..1085552) 1 NC_008563.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1085552 csgD 4495847 csgD Escherichia coli APEC O1 DNA-binding transcriptional regulator CsgD YP_852142.1 1084902 R 405955 CDS YP_852143.1 117623230 4495848 1086278..1086760 1 NC_008563.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1086760 csgB 4495848 csgB Escherichia coli APEC O1 curlin minor subunit YP_852143.1 1086278 D 405955 CDS YP_852144.1 117623231 4495849 1086801..1087256 1 NC_008563.1 cryptic curlin major subunit 1087256 csgA 4495849 csgA Escherichia coli APEC O1 cryptic curlin major subunit YP_852144.1 1086801 D 405955 CDS YP_852145.2 229775974 4495850 1087315..1087647 1 NC_008563.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1087647 csgC 4495850 csgC Escherichia coli APEC O1 autoagglutination protein YP_852145.2 1087315 D 405955 CDS YP_852146.1 117623233 4495851 1087768..1088079 1 NC_008563.1 hypothetical protein 1088079 ymdA 4495851 ymdA Escherichia coli APEC O1 hypothetical protein YP_852146.1 1087768 D 405955 CDS YP_852147.1 117623234 4495852 1088174..1088707 1 NC_008563.1 hypothetical protein 1088707 ymdB 4495852 ymdB Escherichia coli APEC O1 hypothetical protein YP_852147.1 1088174 D 405955 CDS YP_852148.1 117623235 4495853 1088649..1090130 1 NC_008563.1 synthase 1090130 ymdC 4495853 ymdC Escherichia coli APEC O1 synthase YP_852148.1 1088649 D 405955 CDS YP_852149.1 117623236 4495854 complement(1090138..1091295) 1 NC_008563.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1091295 mdoC 4495854 mdoC Escherichia coli APEC O1 glucans biosynthesis protein YP_852149.1 1090138 R 405955 CDS YP_852150.1 117623237 4495855 1091671..1093224 1 NC_008563.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1093224 mdoG 4495855 mdoG Escherichia coli APEC O1 glucan biosynthesis protein G YP_852150.1 1091671 D 405955 CDS YP_852151.1 117623238 4495856 1093187..1095760 1 NC_008563.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1095760 modH 4495856 modH Escherichia coli APEC O1 glucosyltransferase MdoH YP_852151.1 1093187 D 405955 CDS YP_852152.1 117623239 4495857 complement(1096160..1096537) 1 NC_008563.1 Acidic protein msyB; hypothetical protein 1096537 msyB 4495857 msyB Escherichia coli APEC O1 hypothetical protein YP_852152.1 1096160 R 405955 CDS YP_852153.1 117623240 4495858 complement(1096617..1097843) 1 NC_008563.1 YceE/MdtG drug MFS transporter; Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1097843 yceE 4495858 yceE Escherichia coli APEC O1 drug efflux system protein MdtG YP_852153.1 1096617 R 405955 CDS YP_852154.1 117623241 4495859 complement(1098015..1098935) 1 NC_008563.1 Lipid A biosynthesis lauroyl acyltransferase; Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1098935 htrB 4495859 htrB Escherichia coli APEC O1 lipid A biosynthesis lauroyl acyltransferase YP_852154.1 1098015 R 405955 CDS YP_852155.1 117623242 4495860 1099160..1100212 1 NC_008563.1 hypothetical protein 1100212 yceA 4495860 yceA Escherichia coli APEC O1 hypothetical protein YP_852155.1 1099160 D 405955 CDS YP_852156.1 117623243 4495861 complement(1100254..1100829) 1 NC_008563.1 hypothetical protein 1100829 yceI 4495861 yceI Escherichia coli APEC O1 hypothetical protein YP_852156.1 1100254 R 405955 CDS YP_852157.1 117623244 4495862 complement(1100833..1101399) 1 NC_008563.1 cytochrome b561-like protein 2; hypothetical protein 1101399 yceJ 4495862 yceJ Escherichia coli APEC O1 hypothetical protein YP_852157.1 1100833 R 405955 CDS YP_852158.1 117623245 4495863 complement(1101821..1102939) 1 NC_008563.1 N-methyl-L-tryptophan oxidase; catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1102939 solA 4495863 solA Escherichia coli APEC O1 N-methyltryptophan oxidase YP_852158.1 1101821 R 405955 CDS YP_852159.1 117623246 4495864 complement(1103054..1103311) 1 NC_008563.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1103311 bssS 4495864 bssS Escherichia coli APEC O1 biofilm formation regulatory protein BssS YP_852159.1 1103054 R 405955 CDS YP_852160.2 229775973 4494101 complement(1103598..1103843) 1 NC_008563.1 DNA-damage-inducible protein I; DNA damage-inducible protein I 1103843 dinI 4494101 dinI Escherichia coli APEC O1 DNA damage-inducible protein I YP_852160.2 1103598 R 405955 CDS YP_852161.1 117623248 4494102 complement(1103917..1104963) 1 NC_008563.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1104963 pyrC 4494102 pyrC Escherichia coli APEC O1 dihydroorotase YP_852161.1 1103917 R 405955 CDS YP_852162.1 117623249 4494103 complement(1105069..1105686) 1 NC_008563.1 hypothetical protein 1105686 yceB 4494103 yceB Escherichia coli APEC O1 hypothetical protein YP_852162.1 1105069 R 405955 CDS YP_852163.1 117623250 4494104 complement(1105763..1106410) 1 NC_008563.1 cofactor involved in the reduction of disulfides; glutaredoxin 1106410 grxB 4494104 grxB Escherichia coli APEC O1 glutaredoxin YP_852163.1 1105763 R 405955 CDS YP_852164.1 117623251 4494105 complement(1106474..1107712) 1 NC_008563.1 transport protein; Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1107712 yceL 4494105 yceL Escherichia coli APEC O1 multidrug resistance protein MdtH YP_852164.1 1106474 R 405955 CDS YP_852165.1 117623252 4494106 1107918..1108502 1 NC_008563.1 Ribosomal-protein-alanine acetyltransferase; ribosomal-protein-S5-alanine N-acetyltransferase 1108502 rimJ 4494106 rimJ Escherichia coli APEC O1 ribosomal-protein-S5-alanine N-acetyltransferase YP_852165.1 1107918 D 405955 CDS YP_852166.1 117623253 4494107 1108513..1109160 1 NC_008563.1 hypothetical protein 1109160 yceH 4494107 yceH Escherichia coli APEC O1 hypothetical protein YP_852166.1 1108513 D 405955 CDS YP_852167.1 117623254 4494108 1109162..1110085 1 NC_008563.1 predicted oxidoreductase, NAD(P)-binding Rossmann-fold domain; hypothetical protein 1110085 mviM 4494108 mviM Escherichia coli APEC O1 hypothetical protein YP_852167.1 1109162 D 405955 CDS YP_852168.1 117623255 4494109 1110195..1111730 1 NC_008563.1 inner membrane protein; hypothetical protein 1111730 mviN 4494109 mviN Escherichia coli APEC O1 hypothetical protein YP_852168.1 1110195 D 405955 CDS YP_852169.1 117623256 4494110 complement(1111770..1112186) 1 NC_008563.1 flagellar biosynthesis/type III secretory pathway chaperone; flagella synthesis protein FlgN 1112186 flgN 4494110 flgN Escherichia coli APEC O1 flagella synthesis protein FlgN YP_852169.1 1111770 R 405955 CDS YP_852170.1 117623257 4494111 complement(1112191..1112484) 1 NC_008563.1 Negative regulator of flagellin synthesis; regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1112484 flgM 4494111 flgM Escherichia coli APEC O1 anti-sigma-28 factor FlgM YP_852170.1 1112191 R 405955 CDS YP_852171.1 117623258 4494112 complement(1112560..1113219) 1 NC_008563.1 flagellar biosynthesis; assembly of basal-body periplasmic P ring; required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1113219 flgA 4494112 flgA Escherichia coli APEC O1 flagellar basal body P-ring biosynthesis protein FlgA YP_852171.1 1112560 R 405955 CDS YP_852172.1 117623259 4494113 1113374..1113790 1 NC_008563.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1113790 flgB 4494113 flgB Escherichia coli APEC O1 flagellar basal body rod protein FlgB YP_852172.1 1113374 D 405955 CDS YP_852173.1 117623260 4494114 1113794..1114198 1 NC_008563.1 FlgC; with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1114198 flgC 4494114 flgC Escherichia coli APEC O1 flagellar basal body rod protein FlgC YP_852173.1 1113794 D 405955 CDS YP_852174.1 117623261 4494115 1114210..1114905 1 NC_008563.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1114905 flgD 4494115 flgD Escherichia coli APEC O1 flagellar basal body rod modification protein YP_852174.1 1114210 D 405955 CDS YP_852175.1 117623262 4494116 1114930..1116135 1 NC_008563.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1116135 flgE 4494116 flgE Escherichia coli APEC O1 flagellar hook protein FlgE YP_852175.1 1114930 D 405955 CDS YP_852176.1 117623263 4494117 1116155..1116910 1 NC_008563.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1116910 flgF 4494117 flgF Escherichia coli APEC O1 flagellar basal body rod protein FlgF YP_852176.1 1116155 D 405955 CDS YP_852177.1 117623264 4494118 1117082..1117864 1 NC_008563.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1117864 flgG 4494118 flgG Escherichia coli APEC O1 flagellar basal body rod protein FlgG YP_852177.1 1117082 D 405955 CDS YP_852178.1 117623265 4494119 1117908..1118615 1 NC_008563.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1118615 flgH 4494119 flgH Escherichia coli APEC O1 flagellar basal body L-ring protein YP_852178.1 1117908 D 405955 CDS YP_852179.1 117623266 4494120 1118624..1119724 1 NC_008563.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1119724 flgI 4494120 flgI Escherichia coli APEC O1 flagellar basal body P-ring protein YP_852179.1 1118624 D 405955 CDS YP_852180.2 162317581 4495633 1119724..1120665 1 NC_008563.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1120665 flgJ 4495633 flgJ Escherichia coli APEC O1 flagellar rod assembly protein/muramidase FlgJ YP_852180.2 1119724 D 405955 CDS YP_852181.1 117623268 4495634 1120731..1122374 1 NC_008563.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1122374 flgK 4495634 flgK Escherichia coli APEC O1 flagellar hook-associated protein FlgK YP_852181.1 1120731 D 405955 CDS YP_852182.1 117623269 4495635 1122386..1123339 1 NC_008563.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1123339 flgL 4495635 flgL Escherichia coli APEC O1 flagellar hook-associated protein FlgL YP_852182.1 1122386 D 405955 CDS YP_852183.1 117623270 4495636 complement(1123534..1126719) 1 NC_008563.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1126719 rne 4495636 rne Escherichia coli APEC O1 ribonuclease E YP_852183.1 1123534 R 405955 CDS YP_852184.1 117623271 4495637 1126800..1127174 1 NC_008563.1 hypothetical protein 1127174 4495637 APECO1_167 Escherichia coli APEC O1 hypothetical protein YP_852184.1 1126800 D 405955 CDS YP_852185.1 117623272 4495638 1127292..1128251 1 NC_008563.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1128251 4495638 APECO1_168 Escherichia coli APEC O1 23S rRNA pseudouridylate synthase C YP_852185.1 1127292 D 405955 CDS YP_852186.1 117623273 4495639 complement(1128363..1128986) 1 NC_008563.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1128986 yceF 4495639 yceF Escherichia coli APEC O1 Maf-like protein YP_852186.1 1128363 R 405955 CDS YP_852187.1 117623274 4495640 1129146..1129667 1 NC_008563.1 hypothetical protein 1129667 yceD 4495640 yceD Escherichia coli APEC O1 hypothetical protein YP_852187.1 1129146 D 405955 CDS YP_852188.1 117623275 4495641 1130003..1131043 1 NC_008563.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1131043 pslX 4495641 pslX Escherichia coli APEC O1 glycerol-3-phosphate acyltransferase PlsX YP_852188.1 1130003 D 405955 CDS YP_852189.1 117623276 4495642 1131111..1132064 1 NC_008563.1 FabH; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1132064 fabH 4495642 fabH Escherichia coli APEC O1 3-oxoacyl-ACP synthase YP_852189.1 1131111 D 405955 CDS YP_852190.1 117623277 4495643 1132080..1133009 1 NC_008563.1 FabD; malonyl-CoA-[acyl-carrier-protein] transacylase 1133009 fabD 4495643 fabD Escherichia coli APEC O1 malonyl-CoA-[acyl-carrier-protein] transacylase YP_852190.1 1132080 D 405955 CDS YP_852191.1 117623278 4495644 1133022..1133756 1 NC_008563.1 FabG; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1133756 fabG 4495644 fabG Escherichia coli APEC O1 3-ketoacyl-ACP reductase YP_852191.1 1133022 D 405955 CDS YP_852192.1 117623279 4495645 complement(1133913..1134194) 1 NC_008563.1 hypothetical protein 1134194 4495645 APECO1_175 Escherichia coli APEC O1 hypothetical protein YP_852192.1 1133913 R 405955 CDS YP_852193.1 117623280 4495646 1134290..1135531 1 NC_008563.1 FabF; FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1135531 fabF 4495646 fabF Escherichia coli APEC O1 3-oxoacyl-(acyl carrier protein) synthase II YP_852193.1 1134290 D 405955 CDS YP_852194.1 117623281 4495647 1135651..1136460 1 NC_008563.1 PabC; catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1136460 pabC 4495647 pabC Escherichia coli APEC O1 4-amino-4-deoxychorismate lyase YP_852194.1 1135651 D 405955 CDS YP_852195.1 117623282 4495648 1136463..1137485 1 NC_008563.1 hypothetical protein 1137485 yceG 4495648 yceG Escherichia coli APEC O1 hypothetical protein YP_852195.1 1136463 D 405955 CDS YP_852196.1 117623283 4495649 1137475..1138116 1 NC_008563.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1138116 tmk 4495649 tmk Escherichia coli APEC O1 thymidylate kinase YP_852196.1 1137475 D 405955 CDS YP_852197.1 117623284 4495650 1138113..1139117 1 NC_008563.1 HolB; catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1139117 holB 4495650 holB Escherichia coli APEC O1 DNA polymerase III subunit delta' YP_852197.1 1138113 D 405955 CDS YP_852198.1 117623285 4495651 1139128..1139925 1 NC_008563.1 metallodependent hydrolase 1139925 ycfH 4495651 ycfH Escherichia coli APEC O1 metallodependent hydrolase YP_852198.1 1139128 D 405955 CDS YP_852199.1 117623286 4493205 1140220..1141653 1 NC_008563.1 PtsG; phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1141653 ptsG 4493205 ptsG Escherichia coli APEC O1 PTS system glucose-specific transporter subunit IIBC YP_852199.1 1140220 D 405955 CDS YP_852200.1 117623287 4493206 complement(1141713..1143902) 1 NC_008563.1 FhuE; ferric-rhodotorulic acid outer membrane transporter 1143902 fhuE 4493206 fhuE Escherichia coli APEC O1 ferric-rhodotorulic acid outer membrane transporter YP_852200.1 1141713 R 405955 CDS YP_852201.1 117623288 4493207 1144236..1144595 1 NC_008563.1 purine nucleoside phosphoramidase 1144595 ycfF 4493207 ycfF Escherichia coli APEC O1 purine nucleoside phosphoramidase YP_852201.1 1144236 D 405955 CDS YP_852202.1 117623289 4493208 1144598..1144975 1 NC_008563.1 hypothetical protein 1144975 ycfL 4493208 ycfL Escherichia coli APEC O1 hypothetical protein YP_852202.1 1144598 D 405955 CDS YP_852203.1 117623290 4493209 1144989..1145630 1 NC_008563.1 hypothetical protein 1145630 4493209 APECO1_186 Escherichia coli APEC O1 hypothetical protein YP_852203.1 1144989 D 405955 CDS YP_852204.1 117623291 4493210 1145611..1146435 1 NC_008563.1 YcfN; catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1146435 thiK 4493210 thiK Escherichia coli APEC O1 thiamine kinase YP_852204.1 1145611 D 405955 CDS YP_852205.1 117623292 4493211 1146446..1147471 1 NC_008563.1 NagZ; hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1147471 nagZ 4493211 nagZ Escherichia coli APEC O1 beta-hexosaminidase YP_852205.1 1146446 D 405955 CDS YP_852206.1 117623293 4493212 1147437..1148036 1 NC_008563.1 hypothetical protein 1148036 ycfP 4493212 ycfP Escherichia coli APEC O1 hypothetical protein YP_852206.1 1147437 D 405955 CDS YP_852207.1 117623294 4493213 1148459..1149739 1 NC_008563.1 NADH dehydrogenase 1149739 ndh 4493213 ndh Escherichia coli APEC O1 NADH dehydrogenase YP_852207.1 1148459 D 405955 CDS YP_852208.1 117623295 4493214 1149966..1150505 1 NC_008563.1 hypothetical protein 1150505 ycfJ 4493214 ycfJ Escherichia coli APEC O1 hypothetical protein YP_852208.1 1149966 D 405955 CDS YP_852209.1 117623296 4493215 complement(1150567..1151277) 1 NC_008563.1 transcriptional regulator 1151277 ycfQ 4493215 ycfQ Escherichia coli APEC O1 transcriptional regulator YP_852209.1 1150567 R 405955 CDS YP_852210.1 117623297 4493216 1151440..1151697 1 NC_008563.1 hypothetical protein 1151697 ycfR 4493216 ycfR Escherichia coli APEC O1 hypothetical protein YP_852210.1 1151440 D 405955 CDS YP_852211.1 117623298 4493217 complement(1151779..1152741) 1 NC_008563.1 hypothetical protein 1152741 ycfS 4493217 ycfS Escherichia coli APEC O1 hypothetical protein YP_852211.1 1151779 R 405955 CDS YP_852212.1 117623299 4493218 complement(1152886..1156380) 1 NC_008563.1 Mfd; transcription-repair coupling factor 1156380 mfd 4493218 mfd Escherichia coli APEC O1 transcription-repair coupling factor YP_852212.1 1152886 R 405955 CDS YP_852213.1 117623300 4493219 complement(1156460..1157533) 1 NC_008563.1 hypothetical protein 1157533 ycfT 4493219 ycfT Escherichia coli APEC O1 hypothetical protein YP_852213.1 1156460 R 405955 CDS YP_852214.1 117623301 4493220 1157690..1158994 1 NC_008563.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1158994 ycfU 4493220 ycfU Escherichia coli APEC O1 outer membrane-specific lipoprotein transporter subunit LolC YP_852214.1 1157690 D 405955 CDS YP_852215.1 117623302 4493221 1158849..1159688 1 NC_008563.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1159688 lolD 4493221 lolD Escherichia coli APEC O1 lipoprotein transporter ATP-binding subunit YP_852215.1 1158849 D 405955 CDS YP_852216.1 117623303 4493222 1159688..1160932 1 NC_008563.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1160932 ycfW 4493222 ycfW Escherichia coli APEC O1 outer membrane-specific lipoprotein transporter subunit LolE YP_852216.1 1159688 D 405955 CDS YP_852217.1 117623304 4493223 1160961..1161872 1 NC_008563.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1161872 ycfX 4493223 ycfX Escherichia coli APEC O1 N-acetyl-D-glucosamine kinase YP_852217.1 1160961 D 405955 CDS YP_852218.1 117623305 4493224 1161888..1162709 1 NC_008563.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1162709 cobB 4493224 cobB Escherichia coli APEC O1 NAD-dependent deacetylase YP_852218.1 1161888 D 405955 CDS YP_852219.1 117623306 4492291 complement(1162847..1163737) 1 NC_008563.1 hypothetical protein 1163737 ycfZ 4492291 ycfZ Escherichia coli APEC O1 hypothetical protein YP_852219.1 1162847 R 405955 CDS YP_852220.1 117623307 4492292 complement(1163632..1164135) 1 NC_008563.1 hypothetical protein 1164135 ymfA 4492292 ymfA Escherichia coli APEC O1 hypothetical protein YP_852220.1 1163632 R 405955 CDS YP_852221.1 117623308 4492293 complement(1164151..1165197) 1 NC_008563.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1165197 potD 4492293 potD Escherichia coli APEC O1 spermidine/putrescine ABC transporter substrate-binding protein YP_852221.1 1164151 R 405955 CDS YP_852222.1 117623309 4492294 complement(1165194..1165988) 1 NC_008563.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1165988 potC 4492294 potC Escherichia coli APEC O1 spermidine/putrescine ABC transporter membrane protein YP_852222.1 1165194 R 405955 CDS YP_852223.1 117623310 4492295 complement(1165985..1166842) 1 NC_008563.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1166842 potB 4492295 potB Escherichia coli APEC O1 spermidine/putrescine ABC transporter membrane protein YP_852223.1 1165985 R 405955 CDS YP_852224.1 117623311 4492296 complement(1166826..1167962) 1 NC_008563.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1167962 potA 4492296 potA Escherichia coli APEC O1 putrescine/spermidine ABC transporter ATPase YP_852224.1 1166826 R 405955 CDS YP_852225.1 117623312 4492297 1168212..1169438 1 NC_008563.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1169438 pepT 4492297 pepT Escherichia coli APEC O1 peptidase T YP_852225.1 1168212 D 405955 CDS YP_852226.1 117623313 4492298 complement(1169487..1170617) 1 NC_008563.1 hypothetical protein 1170617 ycfD 4492298 ycfD Escherichia coli APEC O1 hypothetical protein YP_852226.1 1169487 R 405955 CDS YP_852227.1 117623314 4492299 complement(1170684..1172144) 1 NC_008563.1 sensor protein PhoQ 1172144 phoQ 4492299 phoQ Escherichia coli APEC O1 sensor protein PhoQ YP_852227.1 1170684 R 405955 CDS YP_852228.1 117623315 4492300 complement(1172144..1172815) 1 NC_008563.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1172815 phoP 4492300 phoP Escherichia coli APEC O1 DNA-binding transcriptional regulator PhoP YP_852228.1 1172144 R 405955 CDS YP_852229.1 117623316 4492301 complement(1172984..1174354) 1 NC_008563.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1174354 purB 4492301 purB Escherichia coli APEC O1 adenylosuccinate lyase YP_852229.1 1172984 R 405955 CDS YP_852230.1 117623317 4492302 complement(1174358..1175005) 1 NC_008563.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1175005 ycfC 4492302 ycfC Escherichia coli APEC O1 hypothetical protein YP_852230.1 1174358 R 405955 CDS YP_852231.1 117623318 4492303 complement(1175035..1176186) 1 NC_008563.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1176186 mnmA 4492303 mnmA Escherichia coli APEC O1 tRNA-specific 2-thiouridylase MnmA YP_852231.1 1175035 R 405955 CDS YP_852232.1 117623319 4492304 complement(1176195..1176656) 1 NC_008563.1 phosphohydrolase 1176656 4492304 APECO1_216 Escherichia coli APEC O1 phosphohydrolase YP_852232.1 1176195 R 405955 CDS YP_852233.1 117623320 4492305 complement(1176666..1177319) 1 NC_008563.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1177319 rluE 4492305 rluE Escherichia coli APEC O1 23S rRNA pseudouridine synthase E YP_852233.1 1176666 R 405955 CDS YP_852234.1 117623321 4492306 1177491..1178741 1 NC_008563.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1178741 4492306 APECO1_218 Escherichia coli APEC O1 isocitrate dehydrogenase YP_852234.1 1177491 D 405955 CDS YP_852235.1 117623322 4492307 complement(1178855..1179997) 1 NC_008563.1 prophage lambda integrase 1179997 int 4492307 int Escherichia coli APEC O1 prophage lambda integrase YP_852235.1 1178855 R 405955 CDS YP_852236.1 117623323 4492308 1180553..1180984 1 NC_008563.1 hypothetical protein 1180984 4492308 APECO1_220 Escherichia coli APEC O1 hypothetical protein YP_852236.1 1180553 D 405955 CDS YP_852237.1 117623324 4492309 complement(1181863..1182543) 1 NC_008563.1 exonuclease encoded by prophage CP-933K 1182543 4492309 APECO1_221 Escherichia coli APEC O1 exonuclease encoded by prophage CP-933K YP_852237.1 1181863 R 405955 CDS YP_852238.1 117623325 4491791 complement(1182540..1183325) 1 NC_008563.1 recombination protein Bet of prophage 1183325 4491791 APECO1_222 Escherichia coli APEC O1 recombination protein Bet of prophage YP_852238.1 1182540 R 405955 CDS YP_852239.1 117623326 4491792 complement(1183331..1183627) 1 NC_008563.1 host-nuclease inhibitor protein Gam of bacteriphage 1183627 gamW 4491792 gamW Escherichia coli APEC O1 host-nuclease inhibitor protein Gam of bacteriphage YP_852239.1 1183331 R 405955 CDS YP_852240.1 117623327 4491793 complement(1183703..1183972) 1 NC_008563.1 Kil protein 1183972 kil1 4491793 kil1 Escherichia coli APEC O1 Kil protein YP_852240.1 1183703 R 405955 CDS YP_852241.1 117623328 4491794 complement(1184052..1184420) 1 NC_008563.1 ssDNA-binding protein 1184420 4491794 APECO1_225 Escherichia coli APEC O1 ssDNA-binding protein YP_852241.1 1184052 R 405955 CDS YP_852242.1 117623329 4491795 1185017..1185598 1 NC_008563.1 superinfection exclusion protein B of prophage 1185598 4491795 APECO1_226 Escherichia coli APEC O1 superinfection exclusion protein B of prophage YP_852242.1 1185017 D 405955 CDS YP_852243.1 117623330 4491796 complement(1185615..1185959) 1 NC_008563.1 N protein 1185959 4491796 APECO1_227 Escherichia coli APEC O1 N protein YP_852243.1 1185615 R 405955 CDS YP_852244.1 117623331 4491797 complement(1186324..1187076) 1 NC_008563.1 hypothetical protein 1187076 4491797 APECO1_228 Escherichia coli APEC O1 hypothetical protein YP_852244.1 1186324 R 405955 CDS YP_852245.1 117623332 4491798 complement(1187073..1187513) 1 NC_008563.1 hypothetical protein 1187513 4491798 APECO1_229 Escherichia coli APEC O1 hypothetical protein YP_852245.1 1187073 R 405955 CDS YP_852246.1 117623333 4491799 complement(1187670..1188365) 1 NC_008563.1 CI repressor of bacteriophage 1188365 4491799 APECO1_230 Escherichia coli APEC O1 CI repressor of bacteriophage YP_852246.1 1187670 R 405955 CDS YP_852247.1 117623334 4491800 1188371..1188655 1 NC_008563.1 hypothetical protein 1188655 4491800 APECO1_231 Escherichia coli APEC O1 hypothetical protein YP_852247.1 1188371 D 405955 CDS YP_852248.1 117623335 4491801 1188797..1189093 1 NC_008563.1 regulatory protein CII of bacteriophage 1189093 4491801 APECO1_232 Escherichia coli APEC O1 regulatory protein CII of bacteriophage YP_852248.1 1188797 D 405955 CDS YP_852249.1 117623336 4491802 1189126..1190025 1 NC_008563.1 replication protein O of bacteriophage 1190025 4491802 APECO1_233 Escherichia coli APEC O1 replication protein O of bacteriophage YP_852249.1 1189126 D 405955 CDS YP_852250.1 117623337 4491803 1190022..1190723 1 NC_008563.1 replication protein P of bacteriophage 1190723 4491803 APECO1_234 Escherichia coli APEC O1 replication protein P of bacteriophage YP_852250.1 1190022 D 405955 CDS YP_852251.1 117623338 4491804 1190720..1191010 1 NC_008563.1 exclusion protein ren of prophage 1191010 4491804 APECO1_235 Escherichia coli APEC O1 exclusion protein ren of prophage YP_852251.1 1190720 D 405955 CDS YP_852252.1 117623339 4491805 1191084..1191524 1 NC_008563.1 hypothetical protein 1191524 ninB 4491805 ninB Escherichia coli APEC O1 hypothetical protein YP_852252.1 1191084 D 405955 CDS YP_852253.1 117623340 4491806 1191461..1192048 1 NC_008563.1 DNA N-6-adenine-methyltransferase of bacteriophage 1192048 4491806 APECO1_237 Escherichia coli APEC O1 DNA N-6-adenine-methyltransferase of bacteriophage YP_852253.1 1191461 D 405955 CDS YP_852254.1 117623341 4491807 1192182..1192565 1 NC_008563.1 hypothetical protein 1192565 4491807 APECO1_238 Escherichia coli APEC O1 hypothetical protein YP_852254.1 1192182 D 405955 CDS YP_852255.1 117623342 4491808 1192772..1193134 1 NC_008563.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1193134 rusA 4491808 rusA Escherichia coli APEC O1 endodeoxyribonuclease RUS YP_852255.1 1192772 D 405955 CDS YP_852256.1 117623343 4491809 1193357..1193740 1 NC_008563.1 similar to lambdoid prophage; antitermination protein Q-like protein 1193740 ybcQ 4491809 ybcQ Escherichia coli APEC O1 antitermination protein Q-like protein YP_852256.1 1193357 D 405955 CDS YP_852257.1 117623344 4491810 complement(1193929..1195071) 1 NC_008563.1 outer membrane porin protein NmpC 1195071 nmpC 4491810 nmpC Escherichia coli APEC O1 outer membrane porin protein NmpC YP_852257.1 1193929 R 405955 CDS YP_852258.1 117623345 4495652 1195815..1196312 1 NC_008563.1 bacteriophage lambda lysozyme-like protein 1196312 ybcS2 4495652 ybcS2 Escherichia coli APEC O1 bacteriophage lambda lysozyme-like protein YP_852258.1 1195815 D 405955 CDS YP_852259.1 117623346 4495653 1196297..1196770 1 NC_008563.1 Rz endopeptidase from lambdoid prophage 1196770 4495653 APECO1_243 Escherichia coli APEC O1 Rz endopeptidase from lambdoid prophage YP_852259.1 1196297 D 405955 CDS YP_852260.1 117623347 4495654 complement(1196802..1197110) 1 NC_008563.1 lambda prophage Bor protein 1197110 bor 4495654 bor Escherichia coli APEC O1 lambda prophage Bor protein YP_852260.1 1196802 R 405955 CDS YP_852261.1 117623348 4495655 1197522..1197902 1 NC_008563.1 truncated TonB-like membrane protein encoded within prophage 1197902 tonB 4495655 tonB Escherichia coli APEC O1 truncated TonB-like membrane protein encoded within prophage YP_852261.1 1197522 D 405955 CDS YP_852262.1 117623349 4495656 complement(1198025..1198378) 1 NC_008563.1 hypothetical protein 1198378 4495656 APECO1_246 Escherichia coli APEC O1 hypothetical protein YP_852262.1 1198025 R 405955 CDS YP_852263.1 117623350 4495657 1198763..1199311 1 NC_008563.1 prophage Qin DNA packaging protein NU1-like protein 1199311 nohA2 4495657 nohA2 Escherichia coli APEC O1 prophage Qin DNA packaging protein NU1-like protein YP_852263.1 1198763 D 405955 CDS YP_852264.1 117623351 4495658 1199241..1201211 1 NC_008563.1 DNA packaging protein of prophage; terminase large subunit 1201211 4495658 APECO1_248 Escherichia coli APEC O1 DNA packaging protein of prophage; terminase large subunit YP_852264.1 1199241 D 405955 CDS YP_852265.1 117623352 4495659 1201368..1202990 1 NC_008563.1 capsid protein of prophage 1202990 4495659 APECO1_249 Escherichia coli APEC O1 capsid protein of prophage YP_852265.1 1201368 D 405955 CDS YP_852266.1 117623353 4495660 1202980..1204485 1 NC_008563.1 head-tail preconnector protein gp5 of bacteriophage 1204485 4495660 APECO1_250 Escherichia coli APEC O1 head-tail preconnector protein gp5 of bacteriophage YP_852266.1 1202980 D 405955 CDS YP_852267.1 117623354 4495661 complement(1204501..1204872) 1 NC_008563.1 hypothetical protein 1204872 4495661 APECO1_251 Escherichia coli APEC O1 hypothetical protein YP_852267.1 1204501 R 405955 CDS YP_852268.1 117623355 4495662 1204927..1205955 1 NC_008563.1 capsid protein of prophage 1205955 4495662 APECO1_252 Escherichia coli APEC O1 capsid protein of prophage YP_852268.1 1204927 D 405955 CDS YP_852269.1 117623356 4495663 1205959..1206381 1 NC_008563.1 hypothetical protein 1206381 4495663 APECO1_253 Escherichia coli APEC O1 hypothetical protein YP_852269.1 1205959 D 405955 CDS YP_852270.1 117623357 4495664 1206338..1206727 1 NC_008563.1 head-tail joining protein of prophage 1206727 4495664 APECO1_254 Escherichia coli APEC O1 head-tail joining protein of prophage YP_852270.1 1206338 D 405955 CDS YP_852271.1 117623358 4495665 1206739..1207317 1 NC_008563.1 tail fiber component Z of prophage 1207317 4495665 APECO1_255 Escherichia coli APEC O1 tail fiber component Z of prophage YP_852271.1 1206739 D 405955 CDS YP_852272.1 117623359 4495666 1207314..1207709 1 NC_008563.1 tail component of prophage 1207709 4495666 APECO1_256 Escherichia coli APEC O1 tail component of prophage YP_852272.1 1207314 D 405955 CDS YP_852273.1 117623360 4495667 1207687..1208457 1 NC_008563.1 tail component of prophage CP-933X 1208457 4495667 APECO1_257 Escherichia coli APEC O1 tail component of prophage CP-933X YP_852273.1 1207687 D 405955 CDS YP_852274.1 117623361 4495668 1208473..1208895 1 NC_008563.1 tail component of prophage 1208895 4495668 APECO1_258 Escherichia coli APEC O1 tail component of prophage YP_852274.1 1208473 D 405955 CDS YP_852275.1 117623362 4495669 1208877..1209311 1 NC_008563.1 tail component of prophage 1209311 4495669 APECO1_259 Escherichia coli APEC O1 tail component of prophage YP_852275.1 1208877 D 405955 CDS YP_852276.1 117623363 4495670 1209304..1211865 1 NC_008563.1 tail component of prophage 1211865 4495670 APECO1_260 Escherichia coli APEC O1 tail component of prophage YP_852276.1 1209304 D 405955 CDS YP_852277.1 117623364 4493625 1211862..1212191 1 NC_008563.1 minor tail protein 1212191 4493625 APECO1_261 Escherichia coli APEC O1 minor tail protein YP_852277.1 1211862 D 405955 CDS YP_852278.1 117623365 4493626 1212191..1212889 1 NC_008563.1 tail component of prophage 1212889 4493626 APECO1_262 Escherichia coli APEC O1 tail component of prophage YP_852278.1 1212191 D 405955 CDS YP_852279.1 117623366 4493627 1212895..1213638 1 NC_008563.1 tail fiber component K of prophage 1213638 4493627 APECO1_263 Escherichia coli APEC O1 tail fiber component K of prophage YP_852279.1 1212895 D 405955 CDS YP_852280.1 117623367 4493628 1213536..1214207 1 NC_008563.1 tail component of prophage 1214207 4493628 APECO1_265 Escherichia coli APEC O1 tail component of prophage YP_852280.1 1213536 D 405955 CDS YP_852281.1 117623368 4493629 1214268..1217018 1 NC_008563.1 tail component of prophage 1217018 4493629 APECO1_266 Escherichia coli APEC O1 tail component of prophage YP_852281.1 1214268 D 405955 CDS YP_852282.1 117623369 4493630 1216993..1217751 1 NC_008563.1 tail component of prophage 1217751 4493630 APECO1_267 Escherichia coli APEC O1 tail component of prophage YP_852282.1 1216993 D 405955 CDS YP_852283.1 117623370 4493631 1217804..1219870 1 NC_008563.1 hypothetical protein 1219870 4493631 APECO1_268 Escherichia coli APEC O1 hypothetical protein YP_852283.1 1217804 D 405955 CDS YP_852284.1 117623371 4493632 1219867..1220145 1 NC_008563.1 hypothetical protein 1220145 4493632 APECO1_269 Escherichia coli APEC O1 hypothetical protein YP_852284.1 1219867 D 405955 CDS YP_852285.1 117623372 4493633 1220158..1220451 1 NC_008563.1 hypothetical protein 1220451 4493633 APECO1_270 Escherichia coli APEC O1 hypothetical protein YP_852285.1 1220158 D 405955 CDS YP_852286.1 117623373 4493634 complement(1220543..1221400) 1 NC_008563.1 Mn+2/Fe+2 ABC transporter inner membrane subunit SitD 1221400 sitD 4493634 sitD Escherichia coli APEC O1 Mn+2/Fe+2 ABC transporter inner membrane subunit SitD YP_852286.1 1220543 R 405955 CDS YP_852287.1 117623374 4493635 complement(1221397..1222254) 1 NC_008563.1 Mn+2/Fe+2 ABC transporter inner membrane subunit SitC 1222254 sitC 4493635 sitC Escherichia coli APEC O1 Mn+2/Fe+2 ABC transporter inner membrane subunit SitC YP_852287.1 1221397 R 405955 CDS YP_852288.1 117623375 4493636 complement(1222251..1223078) 1 NC_008563.1 Mn+2/Fe+2 ABC transporter ATPase SitB 1223078 sitB 4493636 sitB Escherichia coli APEC O1 Mn+2/Fe+2 ABC transporter ATPase SitB YP_852288.1 1222251 R 405955 CDS YP_852289.1 117623376 4493637 complement(1223078..1223992) 1 NC_008563.1 Mn+2/Fe+2 ABC transporter substrate-binding protein 1223992 sitA 4493637 sitA Escherichia coli APEC O1 Mn+2/Fe+2 ABC transporter substrate-binding protein YP_852289.1 1223078 R 405955 CDS YP_852290.1 117623377 4493638 1224679..1225449 1 NC_008563.1 hypothetical protein 1225449 4493638 APECO1_275 Escherichia coli APEC O1 hypothetical protein YP_852290.1 1224679 D 405955 CDS YP_852291.1 117623378 4493639 complement(1226335..1226739) 1 NC_008563.1 hypothetical protein 1226739 ycgX 4493639 ycgX Escherichia coli APEC O1 hypothetical protein YP_852291.1 1226335 R 405955 CDS YP_852292.1 117623379 4493640 complement(1226960..1227691) 1 NC_008563.1 transcriptional regulator 1227691 ycgE 4493640 ycgE Escherichia coli APEC O1 transcriptional regulator YP_852292.1 1226960 R 405955 CDS YP_852293.1 117623380 4493641 complement(1227896..1229107) 1 NC_008563.1 hypothetical protein 1229107 ycgF 4493641 ycgF Escherichia coli APEC O1 hypothetical protein YP_852293.1 1227896 R 405955 CDS YP_852294.1 117623381 4493642 1229700..1229972 1 NC_008563.1 hypothetical protein 1229972 4493642 APECO1_279 Escherichia coli APEC O1 hypothetical protein YP_852294.1 1229700 D 405955 CDS YP_852295.1 117623382 4493643 1230001..1230267 1 NC_008563.1 hypothetical protein 1230267 ymgB 4493643 ymgB Escherichia coli APEC O1 hypothetical protein YP_852295.1 1230001 D 405955 CDS YP_852296.1 117623383 4493644 1231100..1231819 1 NC_008563.1 hypothetical protein 1231819 4493644 APECO1_281 Escherichia coli APEC O1 hypothetical protein YP_852296.1 1231100 D 405955 CDS YP_852297.1 117623384 4491597 1233036..1233413 1 NC_008563.1 hypothetical protein 1233413 4491597 APECO1_282 Escherichia coli APEC O1 hypothetical protein YP_852297.1 1233036 D 405955 CDS YP_852298.1 117623385 4491598 1233559..1234086 1 NC_008563.1 hypothetical protein 1234086 4491598 APECO1_283 Escherichia coli APEC O1 hypothetical protein YP_852298.1 1233559 D 405955 CDS YP_852299.1 117623386 4491599 complement(1234144..1234479) 1 NC_008563.1 hypothetical protein 1234479 4491599 APECO1_284 Escherichia coli APEC O1 hypothetical protein YP_852299.1 1234144 R 405955 CDS YP_852300.1 117623387 4491600 complement(1234483..1234767) 1 NC_008563.1 hypothetical protein 1234767 4491600 APECO1_285 Escherichia coli APEC O1 hypothetical protein YP_852300.1 1234483 R 405955 CDS YP_852301.1 117623388 4491601 1235420..1235746 1 NC_008563.1 hypothetical protein 1235746 4491601 APECO1_286 Escherichia coli APEC O1 hypothetical protein YP_852301.1 1235420 D 405955 CDS YP_852302.1 117623389 4491602 complement(1236119..1236385) 1 NC_008563.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1236385 minE 4491602 minE Escherichia coli APEC O1 cell division topological specificity factor MinE YP_852302.1 1236119 R 405955 CDS YP_852303.1 117623390 4491603 complement(1236389..1237201) 1 NC_008563.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1237201 minD 4491603 minD Escherichia coli APEC O1 cell division inhibitor MinD YP_852303.1 1236389 R 405955 CDS YP_852304.1 117623391 4491604 complement(1237225..1237920) 1 NC_008563.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1237920 minC 4491604 minC Escherichia coli APEC O1 septum formation inhibitor YP_852304.1 1237225 R 405955 CDS YP_852305.1 117623392 4491605 1238440..1238808 1 NC_008563.1 hypothetical protein 1238808 ycgJ 4491605 ycgJ Escherichia coli APEC O1 hypothetical protein YP_852305.1 1238440 D 405955 CDS YP_852306.1 117623393 4491606 complement(1238928..1239329) 1 NC_008563.1 hypothetical protein 1239329 ycgK 4491606 ycgK Escherichia coli APEC O1 hypothetical protein YP_852306.1 1238928 R 405955 CDS YP_852307.1 117623394 4491607 1239538..1239864 1 NC_008563.1 hypothetical protein 1239864 4491607 APECO1_292 Escherichia coli APEC O1 hypothetical protein YP_852307.1 1239538 D 405955 CDS YP_852308.1 117623395 4491608 1239936..1240595 1 NC_008563.1 hypothetical protein 1240595 ycgM 4491608 ycgM Escherichia coli APEC O1 hypothetical protein YP_852308.1 1239936 D 405955 CDS YP_852309.2 162317580 4491609 1240687..1241133 1 NC_008563.1 hypothetical protein 1241133 ycgN 4491609 ycgN Escherichia coli APEC O1 hypothetical protein YP_852309.2 1240687 D 405955 CDS YP_852310.1 117623397 4491610 1241927..1242346 1 NC_008563.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1242346 umuD 4491610 umuD Escherichia coli APEC O1 DNA polymerase V subunit UmuD YP_852310.1 1241927 D 405955 CDS YP_852311.1 117623398 4491611 1242346..1243614 1 NC_008563.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1243614 umuC 4491611 umuC Escherichia coli APEC O1 DNA polymerase V subunit UmuC YP_852311.1 1242346 D 405955 CDS YP_852312.1 117623399 4491612 complement(1243659..1244195) 1 NC_008563.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1244195 dsbB 4491612 dsbB Escherichia coli APEC O1 disulfide bond formation protein B YP_852312.1 1243659 R 405955 CDS YP_852313.1 117623400 4491613 complement(1244335..1245876) 1 NC_008563.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1245876 nhaB 4491613 nhaB Escherichia coli APEC O1 sodium/proton antiporter YP_852313.1 1244335 R 405955 CDS YP_852314.1 117623401 4491614 1246098..1246817 1 NC_008563.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1246817 fadR 4491614 fadR Escherichia coli APEC O1 fatty acid metabolism regulator YP_852314.1 1246098 D 405955 CDS YP_852315.1 117623402 4491615 complement(1246980..1248512) 1 NC_008563.1 SpoVR family protein 1248512 ycgB 4491615 ycgB Escherichia coli APEC O1 SpoVR family protein YP_852315.1 1246980 R 405955 CDS YP_852316.1 117623403 4492425 1248836..1250140 1 NC_008563.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1250140 dadA 4492425 dadA Escherichia coli APEC O1 D-amino acid dehydrogenase small subunit YP_852316.1 1248836 D 405955 CDS YP_852317.1 117623404 4492426 1250150..1251220 1 NC_008563.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1251220 dadX 4492426 dadX Escherichia coli APEC O1 alanine racemase YP_852317.1 1250150 D 405955 CDS YP_852318.1 117623405 4492427 complement(1251277..1252887) 1 NC_008563.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1252887 ycgO 4492427 ycgO Escherichia coli APEC O1 potassium/proton antiporter YP_852318.1 1251277 R 405955 CDS YP_852319.1 117623406 4492428 complement(1253108..1254022) 1 NC_008563.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1254022 ldcA 4492428 ldcA Escherichia coli APEC O1 L,D-carboxypeptidase A YP_852319.1 1253108 R 405955 CDS YP_852320.1 117623407 4492429 1254008..1254733 1 NC_008563.1 murein transglycosylase E 1254733 mltE 4492429 mltE Escherichia coli APEC O1 murein transglycosylase E YP_852320.1 1254008 D 405955 CDS YP_852321.1 117623408 4492430 complement(1254735..1255469) 1 NC_008563.1 hypothetical protein 1255469 4492430 APECO1_306 Escherichia coli APEC O1 hypothetical protein YP_852321.1 1254735 R 405955 CDS YP_852322.1 117623409 4492431 1255670..1255924 1 NC_008563.1 transglycosylase 1255924 ymgE 4492431 ymgE Escherichia coli APEC O1 transglycosylase YP_852322.1 1255670 D 405955 CDS YP_852323.1 117623410 4492432 complement(1255974..1257944) 1 NC_008563.1 TonB dependent outer membrane receptor 1257944 prrA 4492432 prrA Escherichia coli APEC O1 TonB dependent outer membrane receptor YP_852323.1 1255974 R 405955 CDS YP_852324.1 117623411 4492433 complement(1257970..1258824) 1 NC_008563.1 involved in molybdenum transport; molybdenum transport protein ModD 1258824 modD 4492433 modD Escherichia coli APEC O1 molybdenum transport protein ModD YP_852324.1 1257970 R 405955 CDS YP_852325.1 117623412 4492434 complement(1258821..1259633) 1 NC_008563.1 hypothetical protein 1259633 4492434 APECO1_310 Escherichia coli APEC O1 hypothetical protein YP_852325.1 1258821 R 405955 CDS YP_852326.1 117623413 4492435 complement(1259643..1260539) 1 NC_008563.1 iron ABCtransporter ATP-binding protein 1260539 4492435 APECO1_311 Escherichia coli APEC O1 iron ABCtransporter ATP-binding protein YP_852326.1 1259643 R 405955 CDS YP_852327.1 117623414 4492436 complement(1260398..1261378) 1 NC_008563.1 iron ABCtransporter permease protein 1261378 4492436 APECO1_312 Escherichia coli APEC O1 iron ABCtransporter permease protein YP_852327.1 1260398 R 405955 CDS YP_852328.1 117623415 4492437 complement(1261378..1262442) 1 NC_008563.1 iron ABCtransporter periplasmic-binding protein 1262442 4492437 APECO1_313 Escherichia coli APEC O1 iron ABCtransporter periplasmic-binding protein YP_852328.1 1261378 R 405955 CDS YP_852329.1 117623416 4492438 complement(1262737..1264434) 1 NC_008563.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1264434 treA 4492438 treA Escherichia coli APEC O1 trehalase YP_852329.1 1262737 R 405955 CDS YP_852330.1 117623417 4492439 complement(1264753..1266174) 1 NC_008563.1 YcgC; phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM 1266174 ycgC 4492439 ycgC Escherichia coli APEC O1 dihydroxyacetone kinase subunit DhaM YP_852330.1 1264753 R 405955 CDS YP_852331.1 117623418 4492440 complement(1266182..1266889) 1 NC_008563.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1266889 dhaL 4492440 dhaL Escherichia coli APEC O1 dihydroxyacetone kinase subunit DhaL YP_852331.1 1266182 R 405955 CDS YP_852332.1 117623419 4492441 complement(1266825..1267925) 1 NC_008563.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1267925 dhaK 4492441 dhaK Escherichia coli APEC O1 dihydroxyacetone kinase subunit DhaK YP_852332.1 1266825 R 405955 CDS YP_852333.1 117623420 4492442 1268114..1270042 1 NC_008563.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1270042 4492442 APECO1_318 Escherichia coli APEC O1 DNA-binding transcriptional regulator DhaR YP_852333.1 1268114 D 405955 CDS YP_852334.1 117623421 4492443 complement(1270446..1271537) 1 NC_008563.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1271537 ychF 4492443 ychF Escherichia coli APEC O1 GTP-dependent nucleic acid-binding protein EngD YP_852334.1 1270446 R 405955 CDS YP_852335.1 117623422 4492444 complement(1271654..1272037) 1 NC_008563.1 peptidyl-tRNA hydrolase 1272037 pth 4492444 pth Escherichia coli APEC O1 peptidyl-tRNA hydrolase YP_852335.1 1271654 R 405955 CDS YP_852336.1 117623423 4494141 1272516..1272794 1 NC_008563.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1272794 ychH 4494141 ychH Escherichia coli APEC O1 hypothetical protein YP_852336.1 1272516 D 405955 CDS YP_852337.1 117623424 4494142 complement(1272849..1274501) 1 NC_008563.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1274501 ychM 4494142 ychM Escherichia coli APEC O1 sulfate transporter YchM YP_852337.1 1272849 R 405955 CDS YP_852338.1 117623425 4494143 complement(1274653..1275666) 1 NC_008563.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1275666 prsA 4494143 prsA Escherichia coli APEC O1 ribose-phosphate pyrophosphokinase YP_852338.1 1274653 R 405955 CDS YP_852339.1 117623426 4494144 complement(1275751..1276602) 1 NC_008563.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1276602 ipk 4494144 ipk Escherichia coli APEC O1 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_852339.1 1275751 R 405955 CDS YP_852340.1 117623427 4494145 complement(1276602..1277291) 1 NC_008563.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1277291 lolB 4494145 lolB Escherichia coli APEC O1 outer membrane lipoprotein LolB YP_852340.1 1276602 R 405955 CDS YP_852341.1 117623428 4494146 1277439..1278695 1 NC_008563.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1278695 hemA 4494146 hemA Escherichia coli APEC O1 glutamyl-tRNA reductase YP_852341.1 1277439 D 405955 CDS YP_852342.1 117623429 4494147 1278737..1279819 1 NC_008563.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1279819 prfA 4494147 prfA Escherichia coli APEC O1 peptide chain release factor 1 YP_852342.1 1278737 D 405955 CDS YP_852343.1 117623430 4494148 1279819..1280652 1 NC_008563.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1280652 hemK 4494148 hemK Escherichia coli APEC O1 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_852343.1 1279819 D 405955 CDS YP_852344.1 117623431 4494149 1280649..1281041 1 NC_008563.1 transcriptional regulator 1281041 4494149 APECO1_330 Escherichia coli APEC O1 transcriptional regulator YP_852344.1 1280649 D 405955 CDS YP_852345.1 117623432 4494150 1281045..1281854 1 NC_008563.1 transcriptional regulator 1281854 4494150 APECO1_331 Escherichia coli APEC O1 transcriptional regulator YP_852345.1 1281045 D 405955 CDS YP_852346.1 117623433 4494151 1281890..1282744 1 NC_008563.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1282744 4494151 APECO1_332 Escherichia coli APEC O1 2-dehydro-3-deoxyphosphooctonate aldolase YP_852346.1 1281890 D 405955 CDS YP_852347.1 117623434 4494152 complement(1283405..1284592) 1 NC_008563.1 calcium/sodium:proton antiporter 1284592 chaA 4494152 chaA Escherichia coli APEC O1 calcium/sodium:proton antiporter YP_852347.1 1283405 R 405955 CDS YP_852348.1 117623435 4494153 complement(1284769..1285068) 1 NC_008563.1 hypothetical protein 1285068 4494153 APECO1_334 Escherichia coli APEC O1 hypothetical protein YP_852348.1 1284769 R 405955 CDS YP_852349.1 117623436 4494154 1285142..1285858 1 NC_008563.1 cation transport protein ChaC 1285858 chaC 4494154 chaC Escherichia coli APEC O1 cation transport protein ChaC YP_852349.1 1285142 D 405955 CDS YP_852350.1 117623437 4494155 complement(1285902..1286255) 1 NC_008563.1 hypothetical protein 1286255 ychN 4494155 ychN Escherichia coli APEC O1 hypothetical protein YP_852350.1 1285902 R 405955 CDS YP_852351.1 117623438 4494156 1286581..1287834 1 NC_008563.1 hypothetical protein 1287834 ychO 4494156 ychO Escherichia coli APEC O1 hypothetical protein YP_852351.1 1286581 D 405955 CDS YP_852352.1 117623439 4494157 complement(1287835..1288485) 1 NC_008563.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1288485 narL 4494157 narL Escherichia coli APEC O1 transcriptional regulator NarL YP_852352.1 1287835 R 405955 CDS YP_852353.1 117623440 4494158 complement(1288478..1290274) 1 NC_008563.1 nitrate/nitrite sensor protein NarX 1290274 narX 4494158 narX Escherichia coli APEC O1 nitrate/nitrite sensor protein NarX YP_852353.1 1288478 R 405955 CDS YP_852354.1 117623441 4494159 1290613..1292004 1 NC_008563.1 nitrate/nitrite transporter NarK 1292004 narK 4494159 narK Escherichia coli APEC O1 nitrate/nitrite transporter NarK YP_852354.1 1290613 D 405955 CDS YP_852355.1 117623442 4495826 1292397..1296140 1 NC_008563.1 nitrate reductase 1 subunit alpha 1296140 narG 4495826 narG Escherichia coli APEC O1 nitrate reductase 1 subunit alpha YP_852355.1 1292397 D 405955 CDS YP_852356.1 117623443 4495827 1296137..1297675 1 NC_008563.1 nitrate reductase 1 subunit, beta (Fe-S) 1297675 narH 4495827 narH Escherichia coli APEC O1 nitrate reductase 1 subunit, beta (Fe-S) YP_852356.1 1296137 D 405955 CDS YP_852357.1 117623444 4495828 1297672..1298382 1 NC_008563.1 nitrate reductase 1 subunit delta 1298382 narJ 4495828 narJ Escherichia coli APEC O1 nitrate reductase 1 subunit delta YP_852357.1 1297672 D 405955 CDS YP_852358.1 117623445 4495829 1298382..1299059 1 NC_008563.1 respiratory nitrate reductase 1 subunit gamma 1299059 narI 4495829 narI Escherichia coli APEC O1 respiratory nitrate reductase 1 subunit gamma YP_852358.1 1298382 D 405955 CDS YP_852359.1 117623446 4495830 complement(1299112..1300311) 1 NC_008563.1 transposase 1300311 4495830 APECO1_345 Escherichia coli APEC O1 transposase YP_852359.1 1299112 R 405955 CDS YP_852360.1 117623447 4495831 complement(1301104..1301946) 1 NC_008563.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1301946 purU 4495831 purU Escherichia coli APEC O1 formyltetrahydrofolate deformylase YP_852360.1 1301104 R 405955 CDS YP_852361.1 117623448 4495832 complement(1301996..1302454) 1 NC_008563.1 hypothetical protein 1302454 ychJ 4495832 ychJ Escherichia coli APEC O1 hypothetical protein YP_852361.1 1301996 R 405955 CDS YP_852362.1 117623449 4495833 1302528..1303472 1 NC_008563.1 hypothetical protein 1303472 ychK 4495833 ychK Escherichia coli APEC O1 hypothetical protein YP_852362.1 1302528 D 405955 CDS YP_852363.1 117623450 4495834 1303564..1304577 1 NC_008563.1 response regulator of RpoS 1304577 rssB 4495834 rssB Escherichia coli APEC O1 response regulator of RpoS YP_852363.1 1303564 D 405955 CDS YP_852364.1 117623451 4495835 1304779..1305687 1 NC_008563.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1305687 galU 4495835 galU Escherichia coli APEC O1 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_852364.1 1304779 D 405955 CDS YP_852365.1 117623452 4495836 complement(1305831..1306244) 1 NC_008563.1 global DNA-binding transcriptional dual regulator H-NS 1306244 hns 4495836 hns Escherichia coli APEC O1 global DNA-binding transcriptional dual regulator H-NS YP_852365.1 1305831 R 405955 CDS YP_852366.1 117623453 4495837 1306848..1307465 1 NC_008563.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1307465 tdk 4495837 tdk Escherichia coli APEC O1 thymidine kinase YP_852366.1 1306848 D 405955 CDS YP_852367.1 117623454 4495838 complement(1307592..1308797) 1 NC_008563.1 transposase InsG for insertion sequence element IS4 1308797 insG 4495838 insG Escherichia coli APEC O1 transposase InsG for insertion sequence element IS4 YP_852367.1 1307592 R 405955 CDS YP_852368.1 117623455 4495839 complement(1308923..1311598) 1 NC_008563.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1311598 adhE 4495839 adhE Escherichia coli APEC O1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_852368.1 1308923 R 405955 CDS YP_852369.1 117623456 4495840 1312075..1312722 1 NC_008563.1 hypothetical protein 1312722 ychE 4495840 ychE Escherichia coli APEC O1 hypothetical protein YP_852369.1 1312075 D 405955 CDS YP_852370.1 117623457 4495841 complement(1312880..1313176) 1 NC_008563.1 hypothetical protein 1313176 4495841 APECO1_357 Escherichia coli APEC O1 hypothetical protein YP_852370.1 1312880 R 405955 CDS YP_852371.1 117623458 4495842 1313388..1315091 1 NC_008563.1 periplasmic oligopeptide-binding protein 1315091 oppA 4495842 oppA Escherichia coli APEC O1 periplasmic oligopeptide-binding protein YP_852371.1 1313388 D 405955 CDS YP_852372.1 117623459 4495843 1315177..1316097 1 NC_008563.1 oligopeptide transporter permease 1316097 oppB 4495843 oppB Escherichia coli APEC O1 oligopeptide transporter permease YP_852372.1 1315177 D 405955 CDS YP_852373.1 117623460 4495844 1316112..1317020 1 NC_008563.1 oligopeptide transporter subunit 1317020 oppC 4495844 oppC Escherichia coli APEC O1 oligopeptide transporter subunit YP_852373.1 1316112 D 405955 CDS YP_852374.1 117623461 4495845 1317032..1318045 1 NC_008563.1 oligopeptide ABC transporter ATP-binding protein 1318045 oppD 4495845 oppD Escherichia coli APEC O1 oligopeptide ABC transporter ATP-binding protein YP_852374.1 1317032 D 405955 CDS YP_852375.1 117623462 4495346 1318042..1319046 1 NC_008563.1 oligopeptide transport ATP-binding protein OppF 1319046 oppF 4495346 oppF Escherichia coli APEC O1 oligopeptide transport ATP-binding protein OppF YP_852375.1 1318042 D 405955 CDS YP_852376.1 117623463 4495347 complement(1319099..1319506) 1 NC_008563.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1319506 yciU 4495347 yciU Escherichia coli APEC O1 dsDNA-mimic protein YP_852376.1 1319099 R 405955 CDS YP_852377.1 117623464 4495348 complement(1319463..1320923) 1 NC_008563.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1320923 cls 4495348 cls Escherichia coli APEC O1 cardiolipin synthetase YP_852377.1 1319463 R 405955 CDS YP_852378.1 117623465 4495349 1320955..1321239 1 NC_008563.1 hypothetical protein 1321239 4495349 APECO1_365 Escherichia coli APEC O1 hypothetical protein YP_852378.1 1320955 D 405955 CDS YP_852379.1 117623466 4495350 complement(1321294..1322565) 1 NC_008563.1 voltage-gated potassium channel 1322565 kch 4495350 kch Escherichia coli APEC O1 voltage-gated potassium channel YP_852379.1 1321294 R 405955 CDS YP_852380.2 162317579 4495351 complement(1322847..1323143) 1 NC_008563.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1323143 yciI 4495351 yciI Escherichia coli APEC O1 YciI-like protein YP_852380.2 1322847 R 405955 CDS YP_852381.1 117623468 4495352 1323352..1324083 1 NC_008563.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1324083 tonB 4495352 tonB Escherichia coli APEC O1 transporter YP_852381.1 1323352 D 405955 CDS YP_852382.1 117623469 4495353 complement(1324123..1324521) 1 NC_008563.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1324521 4495353 APECO1_369 Escherichia coli APEC O1 acyl-CoA thioester hydrolase YP_852382.1 1324123 R 405955 CDS YP_852383.1 117623470 4495354 complement(1324627..1325166) 1 NC_008563.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1325166 yciB 4495354 yciB Escherichia coli APEC O1 intracellular septation protein A YP_852383.1 1324627 R 405955 CDS YP_852384.1 117623471 4495355 complement(1325196..1325939) 1 NC_008563.1 hypothetical protein 1325939 yciC 4495355 yciC Escherichia coli APEC O1 hypothetical protein YP_852384.1 1325196 R 405955 CDS YP_852385.1 117623472 4495356 1326217..1326933 1 NC_008563.1 receptor for colicin S4; outer membrane protein W 1326933 ompW 4495356 ompW Escherichia coli APEC O1 outer membrane protein W YP_852385.1 1326217 D 405955 CDS YP_852386.1 117623473 4495357 complement(1326979..1328109) 1 NC_008563.1 integrase for prophage CP-933O 1328109 intO 4495357 intO Escherichia coli APEC O1 integrase for prophage CP-933O YP_852386.1 1326979 R 405955 CDS YP_852387.1 117623474 4495358 complement(1328400..1330871) 1 NC_008563.1 exonuclease VIII, ds DNA exonuclease encoded by prophage 1330871 exoO 4495358 exoO Escherichia coli APEC O1 exonuclease VIII, ds DNA exonuclease encoded by prophage YP_852387.1 1328400 R 405955 CDS YP_852388.1 117623475 4495359 1330934..1331479 1 NC_008563.1 hypothetical protein 1331479 4495359 APECO1_375 Escherichia coli APEC O1 hypothetical protein YP_852388.1 1330934 D 405955 CDS YP_852389.1 117623476 4495360 complement(1332735..1333373) 1 NC_008563.1 repressor protein encoded within prophage CP-933O 1333373 4495360 APECO1_376 Escherichia coli APEC O1 repressor protein encoded within prophage CP-933O YP_852389.1 1332735 R 405955 CDS YP_852390.1 117623477 4495361 1333453..1333707 1 NC_008563.1 hypothetical protein 1333707 4495361 APECO1_377 Escherichia coli APEC O1 hypothetical protein YP_852390.1 1333453 D 405955 CDS YP_852391.1 117623478 4495362 1333619..1334116 1 NC_008563.1 hypothetical protein 1334116 4495362 APECO1_378 Escherichia coli APEC O1 hypothetical protein YP_852391.1 1333619 D 405955 CDS YP_852392.1 117623479 4495363 1334188..1335246 1 NC_008563.1 hypothetical protein 1335246 4495363 APECO1_379 Escherichia coli APEC O1 hypothetical protein YP_852392.1 1334188 D 405955 CDS YP_852393.1 117623480 4495364 1335287..1335709 1 NC_008563.1 hypothetical protein 1335709 4495364 APECO1_380 Escherichia coli APEC O1 hypothetical protein YP_852393.1 1335287 D 405955 CDS YP_852394.1 117623481 4495081 1335751..1336863 1 NC_008563.1 hypothetical protein 1336863 4495081 APECO1_381 Escherichia coli APEC O1 hypothetical protein YP_852394.1 1335751 D 405955 CDS YP_852395.1 117623482 4495082 1336879..1337880 1 NC_008563.1 hypothetical protein 1337880 4495082 APECO1_382 Escherichia coli APEC O1 hypothetical protein YP_852395.1 1336879 D 405955 CDS YP_852396.1 117623483 4495083 1337992..1338282 1 NC_008563.1 hypothetical protein 1338282 4495083 APECO1_383 Escherichia coli APEC O1 hypothetical protein YP_852396.1 1337992 D 405955 CDS YP_852397.1 117623484 4495084 1338692..1339099 1 NC_008563.1 hypothetical protein 1339099 4495084 APECO1_384 Escherichia coli APEC O1 hypothetical protein YP_852397.1 1338692 D 405955 CDS YP_852398.1 117623485 4495085 1339101..1340147 1 NC_008563.1 hypothetical protein 1340147 ydfU 4495085 ydfU Escherichia coli APEC O1 hypothetical protein YP_852398.1 1339101 D 405955 CDS YP_852399.1 117623486 4495086 1340160..1340534 1 NC_008563.1 endodeoxyribonuclease RusA 1340534 rusA 4495086 rusA Escherichia coli APEC O1 endodeoxyribonuclease RusA YP_852399.1 1340160 D 405955 CDS YP_852400.1 117623487 4495087 1340531..1341352 1 NC_008563.1 cryptic prophage CP-933M antitermination protein Q-like protein 1341352 4495087 APECO1_387 Escherichia coli APEC O1 cryptic prophage CP-933M antitermination protein Q-like protein YP_852400.1 1340531 D 405955 CDS YP_852401.1 117623488 4495088 1341925..1342974 1 NC_008563.1 DNA adenine methyltransferase encoded by prophage CP-933O 1342974 4495088 APECO1_388 Escherichia coli APEC O1 DNA adenine methyltransferase encoded by prophage CP-933O YP_852401.1 1341925 D 405955 CDS YP_852402.1 117623489 4495089 1344156..1344476 1 NC_008563.1 lambdoid prophage DLP12 lysis protein S-like protein 1344476 4495089 APECO1_389 Escherichia coli APEC O1 lambdoid prophage DLP12 lysis protein S-like protein YP_852402.1 1344156 D 405955 CDS YP_852403.1 117623490 4495090 1344481..1344825 1 NC_008563.1 YdfR; hypothetical protein 1344825 ydfR 4495090 ydfR Escherichia coli APEC O1 hypothetical protein YP_852403.1 1344481 D 405955 CDS YP_852404.1 117623491 4495091 complement(1344791..1345063) 1 NC_008563.1 hypothetical protein 1345063 4495091 APECO1_391 Escherichia coli APEC O1 hypothetical protein YP_852404.1 1344791 R 405955 CDS YP_852405.1 117623492 4495092 1345263..1345703 1 NC_008563.1 phage lysozyme 1345703 4495092 APECO1_392 Escherichia coli APEC O1 phage lysozyme YP_852405.1 1345263 D 405955 CDS YP_852406.1 117623493 4495093 complement(1345646..1345933) 1 NC_008563.1 hypothetical protein 1345933 4495093 APECO1_393 Escherichia coli APEC O1 hypothetical protein YP_852406.1 1345646 R 405955 CDS YP_852407.1 117623494 4495094 1346002..1346466 1 NC_008563.1 bacteriophage lambda cell lysis protein 1346466 4495094 APECO1_394 Escherichia coli APEC O1 bacteriophage lambda cell lysis protein YP_852407.1 1346002 D 405955 CDS YP_852408.1 117623495 4494005 complement(1346774..1347199) 1 NC_008563.1 YdfO; hypothetical protein 1347199 ydfO 4494005 ydfO Escherichia coli APEC O1 hypothetical protein YP_852408.1 1346774 R 405955 CDS YP_852409.1 117623496 4494006 1347623..1348411 1 NC_008563.1 prophage Qin DNA packaging protein NU1-like protein 1348411 nohA2 4494006 nohA2 Escherichia coli APEC O1 prophage Qin DNA packaging protein NU1-like protein YP_852409.1 1347623 D 405955 CDS YP_852410.1 117623497 4494007 1348341..1350311 1 NC_008563.1 DNA packaging protein of prophage; terminase large subunit 1350311 4494007 APECO1_397 Escherichia coli APEC O1 DNA packaging protein of prophage; terminase large subunit YP_852410.1 1348341 D 405955 CDS YP_852411.1 117623498 4494008 1350498..1352090 1 NC_008563.1 capsid protein of prophage 1352090 4494008 APECO1_398 Escherichia coli APEC O1 capsid protein of prophage YP_852411.1 1350498 D 405955 CDS YP_852412.1 117623499 4494009 1352080..1353585 1 NC_008563.1 capsid assembly protein of prophage 1353585 4494009 APECO1_399 Escherichia coli APEC O1 capsid assembly protein of prophage YP_852412.1 1352080 D 405955 CDS YP_852413.1 117623500 4494010 complement(1353601..1353972) 1 NC_008563.1 hypothetical protein 1353972 4494010 APECO1_400 Escherichia coli APEC O1 hypothetical protein YP_852413.1 1353601 R 405955 CDS YP_852414.1 117623501 4494011 1354027..1355055 1 NC_008563.1 capsid protein of prophage 1355055 4494011 APECO1_401 Escherichia coli APEC O1 capsid protein of prophage YP_852414.1 1354027 D 405955 CDS YP_852415.1 117623502 4494012 1355059..1355490 1 NC_008563.1 hypothetical protein 1355490 4494012 APECO1_402 Escherichia coli APEC O1 hypothetical protein YP_852415.1 1355059 D 405955 CDS YP_852416.1 117623503 4494013 1355483..1355836 1 NC_008563.1 head-tail joining protein of prophage 1355836 4494013 APECO1_403 Escherichia coli APEC O1 head-tail joining protein of prophage YP_852416.1 1355483 D 405955 CDS YP_852417.1 117623504 4494014 1355852..1356385 1 NC_008563.1 minor tail protein 1356385 4494014 APECO1_404 Escherichia coli APEC O1 minor tail protein YP_852417.1 1355852 D 405955 CDS YP_852418.1 117623505 4494015 1356382..1356777 1 NC_008563.1 tail component of prophage 1356777 4494015 APECO1_405 Escherichia coli APEC O1 tail component of prophage YP_852418.1 1356382 D 405955 CDS YP_852419.1 117623506 4494016 complement(1356878..1358212) 1 NC_008563.1 hypothetical protein 1358212 4494016 APECO1_406 Escherichia coli APEC O1 hypothetical protein YP_852419.1 1356878 R 405955 CDS YP_852420.1 117623507 4494017 1358403..1360976 1 NC_008563.1 tail component of prophage CP-933O 1360976 4494017 APECO1_407 Escherichia coli APEC O1 tail component of prophage CP-933O YP_852420.1 1358403 D 405955 CDS YP_852421.1 117623508 4494020 1360973..1361302 1 NC_008563.1 minor tail protein 1361302 4494020 APECO1_408 Escherichia coli APEC O1 minor tail protein YP_852421.1 1360973 D 405955 CDS YP_852422.1 117623509 4494021 1361302..1362000 1 NC_008563.1 minor tail protein 1362000 4494021 APECO1_409 Escherichia coli APEC O1 minor tail protein YP_852422.1 1361302 D 405955 CDS YP_852423.1 117623510 4494022 1362005..1362748 1 NC_008563.1 tail fiber component K of prophage 1362748 4494022 APECO1_410 Escherichia coli APEC O1 tail fiber component K of prophage YP_852423.1 1362005 D 405955 CDS YP_852424.1 117623511 4494023 1362646..1363287 1 NC_008563.1 tail component of prophage CP-933K 1363287 4494023 APECO1_411 Escherichia coli APEC O1 tail component of prophage CP-933K YP_852424.1 1362646 D 405955 CDS YP_852425.1 117623512 4493165 1363361..1363699 1 NC_008563.1 hypothetical protein 1363699 4493165 APECO1_412 Escherichia coli APEC O1 hypothetical protein YP_852425.1 1363361 D 405955 CDS YP_852426.1 117623513 4493166 1363766..1367245 1 NC_008563.1 tail component of prophage 1367245 4493166 APECO1_413 Escherichia coli APEC O1 tail component of prophage YP_852426.1 1363766 D 405955 CDS YP_852427.1 117623514 4493168 1367313..1367912 1 NC_008563.1 hypothetical protein 1367912 4493168 APECO1_414 Escherichia coli APEC O1 hypothetical protein YP_852427.1 1367313 D 405955 CDS YP_852428.1 117623515 4493169 1368064..1371171 1 NC_008563.1 tail fiber protein 1371171 4493169 APECO1_415 Escherichia coli APEC O1 tail fiber protein YP_852428.1 1368064 D 405955 CDS YP_852429.1 117623516 4493170 1371171..1371755 1 NC_008563.1 phage-related tail fiber assembly protein G 1371755 ynaC 4493170 ynaC Escherichia coli APEC O1 phage-related tail fiber assembly protein G YP_852429.1 1371171 D 405955 CDS YP_852430.1 117623517 4493171 complement(1371810..1372478) 1 NC_008563.1 hypothetical protein 1372478 4493171 APECO1_417 Escherichia coli APEC O1 hypothetical protein YP_852430.1 1371810 R 405955 CDS YP_852431.1 117623518 4493172 complement(1372624..1372974) 1 NC_008563.1 hypothetical protein 1372974 4493172 APECO1_418 Escherichia coli APEC O1 hypothetical protein YP_852431.1 1372624 R 405955 CDS YP_852432.1 117623519 4493173 complement(1373577..1374083) 1 NC_008563.1 hypothetical protein 1374083 4493173 APECO1_419 Escherichia coli APEC O1 hypothetical protein YP_852432.1 1373577 R 405955 CDS YP_852433.1 117623520 4493174 complement(1374129..1374650) 1 NC_008563.1 hypothetical protein 1374650 yciF 4493174 yciF Escherichia coli APEC O1 hypothetical protein YP_852433.1 1374129 R 405955 CDS YP_852434.1 117623521 4493175 complement(1375275..1376081) 1 NC_008563.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1376081 trpA 4493175 trpA Escherichia coli APEC O1 tryptophan synthase subunit alpha YP_852434.1 1375275 R 405955 CDS YP_852435.1 117623522 4493176 complement(1376081..1377274) 1 NC_008563.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1377274 trpB 4493176 trpB Escherichia coli APEC O1 tryptophan synthase subunit beta YP_852435.1 1376081 R 405955 CDS YP_852436.1 117623523 4493177 complement(1377286..1378644) 1 NC_008563.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1378644 trpC 4493177 trpC Escherichia coli APEC O1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_852436.1 1377286 R 405955 CDS YP_852437.1 117623524 4493178 complement(1378648..1380243) 1 NC_008563.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1380243 trpD 4493178 trpD Escherichia coli APEC O1 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_852437.1 1378648 R 405955 CDS YP_852438.1 117623525 4493179 complement(1380243..1381805) 1 NC_008563.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1381805 trpE 4493179 trpE Escherichia coli APEC O1 anthranilate synthase component I YP_852438.1 1380243 R 405955 CDS YP_852439.1 117623526 4493180 1382100..1382960 1 NC_008563.1 hypothetical protein 1382960 trpH 4493180 trpH Escherichia coli APEC O1 hypothetical protein YP_852439.1 1382100 D 405955 CDS YP_852440.1 117623527 4493181 1382921..1383577 1 NC_008563.1 hypothetical protein 1383577 4493181 APECO1_427 Escherichia coli APEC O1 hypothetical protein YP_852440.1 1382921 D 405955 CDS YP_852441.1 117623528 4493182 1383602..1385500 1 NC_008563.1 hypothetical protein 1385500 yciQ 4493182 yciQ Escherichia coli APEC O1 hypothetical protein YP_852441.1 1383602 D 405955 CDS YP_852442.1 117623529 4493183 1385713..1386588 1 NC_008563.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1386588 rluB 4493183 rluB Escherichia coli APEC O1 23S rRNA pseudouridylate synthase B YP_852442.1 1385713 D 405955 CDS YP_852443.1 117623530 4493184 complement(1386628..1387218) 1 NC_008563.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1387218 btuR 4493184 btuR Escherichia coli APEC O1 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_852443.1 1386628 R 405955 CDS YP_852444.1 117623531 4492221 complement(1387215..1387973) 1 NC_008563.1 short chain dehydrogenase 1387973 yciK 4492221 yciK Escherichia coli APEC O1 short chain dehydrogenase YP_852444.1 1387215 R 405955 CDS YP_852445.1 117623532 4492222 1388193..1389242 1 NC_008563.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1389242 sohB 4492222 sohB Escherichia coli APEC O1 periplasmic protease YP_852445.1 1388193 D 405955 CDS YP_852446.1 117623533 4492223 complement(1389278..1389529) 1 NC_008563.1 hypothetical protein 1389529 4492223 APECO1_433 Escherichia coli APEC O1 hypothetical protein YP_852446.1 1389278 R 405955 CDS YP_852447.1 117623534 4492224 1389867..1392506 1 NC_008563.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1392506 topA 4492224 topA Escherichia coli APEC O1 DNA topoisomerase I YP_852447.1 1389867 D 405955 CDS YP_852448.1 117623535 4492225 1392716..1393690 1 NC_008563.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1393690 cysB 4492225 cysB Escherichia coli APEC O1 transcriptional regulator CysB YP_852448.1 1392716 D 405955 CDS YP_852449.1 117623536 4492226 1394678..1397353 1 NC_008563.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1397353 acnA 4492226 acnA Escherichia coli APEC O1 aconitate hydratase YP_852449.1 1394678 D 405955 CDS YP_852450.1 117623537 4492227 complement(1397417..1398070) 1 NC_008563.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1398070 ribA 4492227 ribA Escherichia coli APEC O1 GTP cyclohydrolase II YP_852450.1 1397417 R 405955 CDS YP_852451.1 117623538 4492228 1398177..1398941 1 NC_008563.1 phosphatidylglycerophosphatase B 1398941 pgpB 4492228 pgpB Escherichia coli APEC O1 phosphatidylglycerophosphatase B YP_852451.1 1398177 D 405955 CDS YP_852452.1 117623539 4492229 1399090..1399398 1 NC_008563.1 hypothetical protein 1399398 yciS 4492229 yciS Escherichia coli APEC O1 hypothetical protein YP_852452.1 1399090 D 405955 CDS YP_852453.1 117623540 4492230 1399405..1400574 1 NC_008563.1 tetratricopeptide repeat protein 1400574 yciM 4492230 yciM Escherichia coli APEC O1 tetratricopeptide repeat protein YP_852453.1 1399405 D 405955 CDS YP_852454.1 117623541 4492231 1400706..1401491 1 NC_008563.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1401491 pyrF 4492231 pyrF Escherichia coli APEC O1 orotidine 5'-phosphate decarboxylase YP_852454.1 1400706 D 405955 CDS YP_852455.1 117623542 4492232 1401500..1401829 1 NC_008563.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1401829 yciH 4492232 yciH Escherichia coli APEC O1 translation initiation factor Sui1 YP_852455.1 1401500 D 405955 CDS YP_852456.1 117623543 4492233 complement(1402442..1403191) 1 NC_008563.1 DEOR-type transcriptional regulator 1403191 4492233 APECO1_443 Escherichia coli APEC O1 DEOR-type transcriptional regulator YP_852456.1 1402442 R 405955 CDS YP_852457.1 117623544 4492234 complement(1403602..1405587) 1 NC_008563.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1405587 yciR 4492234 yciR Escherichia coli APEC O1 RNase II stability modulator YP_852457.1 1403602 R 405955 CDS YP_852458.1 117623545 4492235 complement(1405822..1407756) 1 NC_008563.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1407756 rnb 4492235 rnb Escherichia coli APEC O1 exoribonuclease II YP_852458.1 1405822 R 405955 CDS YP_852459.1 117623546 4492236 complement(1407824..1408951) 1 NC_008563.1 hypothetical protein 1408951 yciW 4492236 yciW Escherichia coli APEC O1 hypothetical protein YP_852459.1 1407824 R 405955 CDS YP_852460.1 117623547 4492237 complement(1409096..1409884) 1 NC_008563.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 1409884 fabI 4492237 fabI Escherichia coli APEC O1 enoyl-(acyl carrier protein) reductase YP_852460.1 1409096 R 405955 CDS YP_852461.1 117623548 4492238 1410341..1410928 1 NC_008563.1 transcription regulatory protein 1410928 4492238 APECO1_448 Escherichia coli APEC O1 transcription regulatory protein YP_852461.1 1410341 D 405955 CDS YP_852462.1 117623549 4492239 1411044..1412198 1 NC_008563.1 acriflavine resistance protein A precursor 1412198 4492239 APECO1_449 Escherichia coli APEC O1 acriflavine resistance protein A precursor YP_852462.1 1411044 D 405955 CDS YP_852463.1 117623550 4492182 1412198..1415305 1 NC_008563.1 acriflavine resistance protein B 1415305 4492182 APECO1_450 Escherichia coli APEC O1 acriflavine resistance protein B YP_852463.1 1412198 D 405955 CDS YP_852464.1 117623551 4492183 1415309..1416682 1 NC_008563.1 outer membrane channel protein 1416682 4492183 APECO1_451 Escherichia coli APEC O1 outer membrane channel protein YP_852464.1 1415309 D 405955 CDS YP_852465.1 117623552 4492184 1416691..1417854 1 NC_008563.1 membrane transport protein 1417854 4492184 APECO1_452 Escherichia coli APEC O1 membrane transport protein YP_852465.1 1416691 D 405955 CDS YP_852466.1 117623553 4492185 complement(1417902..1418708) 1 NC_008563.1 peptide ABC transporter ATP-binding protein 1418708 sapF 4492185 sapF Escherichia coli APEC O1 peptide ABC transporter ATP-binding protein YP_852466.1 1417902 R 405955 CDS YP_852467.1 117623554 4492186 complement(1418710..1419702) 1 NC_008563.1 SapD; peptide ABC transporter ATP-binding protein 1419702 sapD 4492186 sapD Escherichia coli APEC O1 peptide ABC transporter ATP-binding protein YP_852467.1 1418710 R 405955 CDS YP_852468.1 117623555 4492187 complement(1419702..1420592) 1 NC_008563.1 SapC; peptide ABC transporter permease 1420592 sapC 4492187 sapC Escherichia coli APEC O1 peptide ABC transporter permease YP_852468.1 1419702 R 405955 CDS YP_852469.1 117623556 4492188 complement(1420579..1421544) 1 NC_008563.1 peptide transport system permease SapB 1421544 sapB 4492188 sapB Escherichia coli APEC O1 peptide transport system permease SapB YP_852469.1 1420579 R 405955 CDS YP_852470.1 117623557 4492189 complement(1421541..1423184) 1 NC_008563.1 peptide transport periplasmic protein SapA 1423184 sapA 4492189 sapA Escherichia coli APEC O1 peptide transport periplasmic protein SapA YP_852470.1 1421541 R 405955 CDS YP_852471.1 117623558 4492190 complement(1424169..1425161) 1 NC_008563.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1425161 pspF 4492190 pspF Escherichia coli APEC O1 phage shock protein operon transcriptional activator YP_852471.1 1424169 R 405955 CDS YP_852472.1 117623559 4492191 1425312..1425980 1 NC_008563.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1425980 pspA 4492191 pspA Escherichia coli APEC O1 phage shock protein PspA YP_852472.1 1425312 D 405955 CDS YP_852473.1 117623560 4492192 1426258..1426617 1 NC_008563.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1426617 pspC 4492192 pspC Escherichia coli APEC O1 DNA-binding transcriptional activator PspC YP_852473.1 1426258 D 405955 CDS YP_852474.1 117623561 4492193 1426922..1427236 1 NC_008563.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1427236 pspE 4492193 pspE Escherichia coli APEC O1 thiosulfate:cyanide sulfurtransferase YP_852474.1 1426922 D 405955 CDS YP_852475.1 117623562 4492194 1427419..1429125 1 NC_008563.1 sucrose phosphorylase 1429125 ycjM 4492194 ycjM Escherichia coli APEC O1 sucrose phosphorylase YP_852475.1 1427419 D 405955 CDS YP_852476.1 117623563 4492195 1429139..1430431 1 NC_008563.1 ABC transporter substrate-binding protein 1430431 ycjN 4492195 ycjN Escherichia coli APEC O1 ABC transporter substrate-binding protein YP_852476.1 1429139 D 405955 CDS YP_852477.1 117623564 4492196 1430452..1431333 1 NC_008563.1 binding-protein dependent transport protein 1431333 ycjO 4492196 ycjO Escherichia coli APEC O1 binding-protein dependent transport protein YP_852477.1 1430452 D 405955 CDS YP_852478.1 117623565 4492197 1431320..1432162 1 NC_008563.1 ABC transporter permease 1432162 ycjP 4492197 ycjP Escherichia coli APEC O1 ABC transporter permease YP_852478.1 1431320 D 405955 CDS YP_852479.1 117623566 4492198 1432193..1432915 1 NC_008563.1 zinc-type alcohol dehydrogenase-like protein YcjQ 1432915 ycjQ 4492198 ycjQ Escherichia coli APEC O1 zinc-type alcohol dehydrogenase-like protein YcjQ YP_852479.1 1432193 D 405955 CDS YP_852480.1 117623567 4492199 1433255..1434052 1 NC_008563.1 transient receptor potential locus 1434052 ycjR 4492199 ycjR Escherichia coli APEC O1 transient receptor potential locus YP_852480.1 1433255 D 405955 CDS YP_852481.1 117623568 4492200 1434062..1435117 1 NC_008563.1 oxidoreductase YcjS 1435117 ycjS 4492200 ycjS Escherichia coli APEC O1 oxidoreductase YcjS YP_852481.1 1434062 D 405955 CDS YP_852482.1 117623569 4492201 1435114..1437381 1 NC_008563.1 transporter 1437381 ycjT 4492201 ycjT Escherichia coli APEC O1 transporter YP_852482.1 1435114 D 405955 CDS YP_852483.1 117623570 4491538 1437378..1438037 1 NC_008563.1 beta-phosphoglucomutase 1438037 ycjU 4491538 ycjU Escherichia coli APEC O1 beta-phosphoglucomutase YP_852483.1 1437378 D 405955 CDS YP_852484.1 117623571 4491539 1438051..1439133 1 NC_008563.1 ABC transporter ATP-binding protein 1439133 ycjV 4491539 ycjV Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_852484.1 1438051 D 405955 CDS YP_852485.1 117623572 4491540 1439178..1440083 1 NC_008563.1 outer membrane protein G 1440083 ompG 4491540 ompG Escherichia coli APEC O1 outer membrane protein G YP_852485.1 1439178 D 405955 CDS YP_852486.1 117623573 4491541 complement(1440134..1441132) 1 NC_008563.1 transcriptional regulator YcjW 1441132 ycjW 4491541 ycjW Escherichia coli APEC O1 transcriptional regulator YcjW YP_852486.1 1440134 R 405955 CDS YP_852487.1 117623574 4491542 1441216..1442685 1 NC_008563.1 hypothetical protein 1442685 ycjX 4491542 ycjX Escherichia coli APEC O1 hypothetical protein YP_852487.1 1441216 D 405955 CDS YP_852488.1 117623575 4491543 1442682..1443743 1 NC_008563.1 hypothetical protein 1443743 ycjF 4491543 ycjF Escherichia coli APEC O1 hypothetical protein YP_852488.1 1442682 D 405955 CDS YP_852489.1 117623576 4491544 1443891..1445432 1 NC_008563.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1445432 tyrR 4491544 tyrR Escherichia coli APEC O1 DNA-binding transcriptional regulator TyrR YP_852489.1 1443891 D 405955 CDS YP_852490.1 117623577 4491545 complement(1445476..1445982) 1 NC_008563.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1445982 tpx 4491545 tpx Escherichia coli APEC O1 thiol peroxidase YP_852490.1 1445476 R 405955 CDS YP_852491.1 117623578 4491546 1446101..1447066 1 NC_008563.1 hypothetical protein 1447066 ycjG 4491546 ycjG Escherichia coli APEC O1 hypothetical protein YP_852491.1 1446101 D 405955 CDS YP_852492.1 117623579 4491547 complement(1447041..1447769) 1 NC_008563.1 murein peptide amidase A 1447769 ycjI 4491547 ycjI Escherichia coli APEC O1 murein peptide amidase A YP_852492.1 1447041 R 405955 CDS YP_852493.1 117623580 4491548 complement(1448060..1448698) 1 NC_008563.1 hypothetical protein 1448698 4491548 APECO1_480 Escherichia coli APEC O1 hypothetical protein YP_852493.1 1448060 R 405955 CDS YP_852494.1 117623581 4491549 complement(1448769..1449701) 1 NC_008563.1 hypothetical protein 1449701 ycjY 4491549 ycjY Escherichia coli APEC O1 hypothetical protein YP_852494.1 1448769 R 405955 CDS YP_852495.1 117623582 4491550 1449827..1450726 1 NC_008563.1 transcriptional regulator YcjZ 1450726 ycjZ 4491550 ycjZ Escherichia coli APEC O1 transcriptional regulator YcjZ YP_852495.1 1449827 D 405955 CDS YP_852496.1 117623583 4491551 1451042..1452676 1 NC_008563.1 periplasmic murein peptide-binding protein 1452676 mppA 4491551 mppA Escherichia coli APEC O1 periplasmic murein peptide-binding protein YP_852496.1 1451042 D 405955 CDS YP_852497.1 117623584 4491552 complement(1452727..1453758) 1 NC_008563.1 hypothetical protein 1453758 ynaI 4491552 ynaI Escherichia coli APEC O1 hypothetical protein YP_852497.1 1452727 R 405955 CDS YP_852498.1 117623585 4491553 1454002..1454259 1 NC_008563.1 hypothetical protein 1454259 ynaJ 4491553 ynaJ Escherichia coli APEC O1 hypothetical protein YP_852498.1 1454002 D 405955 CDS YP_852499.1 117623586 4491554 complement(1454309..1455259) 1 NC_008563.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1455259 4491554 APECO1_486 Escherichia coli APEC O1 universal stress protein UspE YP_852499.1 1454309 R 405955 CDS YP_852500.1 117623587 4491555 complement(1455411..1456205) 1 NC_008563.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1456205 fnr 4491555 fnr Escherichia coli APEC O1 fumarate/nitrate reduction transcriptional regulator YP_852500.1 1455411 R 405955 CDS YP_852501.1 117623588 4491556 complement(1456358..1456873) 1 NC_008563.1 O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1456873 ogt 4491556 ogt Escherichia coli APEC O1 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_852501.1 1456358 R 405955 CDS YP_852502.1 117623589 4495671 complement(1457404..1458219) 1 NC_008563.1 hypothetical protein 1458219 4495671 APECO1_489 Escherichia coli APEC O1 hypothetical protein YP_852502.1 1457404 R 405955 CDS YP_852503.1 117623590 4495672 1458313..1459344 1 NC_008563.1 secretion protein 1459344 hlyD 4495672 hlyD Escherichia coli APEC O1 secretion protein YP_852503.1 1458313 D 405955 CDS YP_852504.1 117623591 4495673 1459341..1460855 1 NC_008563.1 transporter 1460855 4495673 APECO1_491 Escherichia coli APEC O1 transporter YP_852504.1 1459341 D 405955 CDS YP_852505.1 117623592 4495674 1461050..1461613 1 NC_008563.1 hypothetical protein 1461613 ydaL 4495674 ydaL Escherichia coli APEC O1 hypothetical protein YP_852505.1 1461050 D 405955 CDS YP_852506.1 117623593 4495675 complement(1461634..1462926) 1 NC_008563.1 hypothetical protein 1462926 ydaM 4495675 ydaM Escherichia coli APEC O1 hypothetical protein YP_852506.1 1461634 R 405955 CDS YP_852507.1 117623594 4495676 1463121..1464104 1 NC_008563.1 zinc transporter 1464104 zntB 4495676 zntB Escherichia coli APEC O1 zinc transporter YP_852507.1 1463121 D 405955 CDS YP_852508.1 117623595 4495678 1464582..1465955 1 NC_008563.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1465955 dbpA 4495678 dbpA Escherichia coli APEC O1 ATP-dependent RNA helicase DbpA YP_852508.1 1464582 D 405955 CDS YP_852509.1 117623596 4495679 complement(1466084..1467019) 1 NC_008563.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1467019 ydaO 4495679 ydaO Escherichia coli APEC O1 C32 tRNA thiolase YP_852509.1 1466084 R 405955 CDS YP_852510.1 117623597 4495680 complement(1467071..1468306) 1 NC_008563.1 Rac prophage; integrase 1468306 intR 4495680 intR Escherichia coli APEC O1 Rac prophage; integrase YP_852510.1 1467071 R 405955 CDS YP_852511.1 117623598 4495682 complement(1468623..1468883) 1 NC_008563.1 Rac prophage; hypothetical protein 1468883 ydaC 4495682 ydaC Escherichia coli APEC O1 hypothetical protein YP_852511.1 1468623 R 405955 CDS YP_852512.1 117623599 4495683 complement(1469055..1469921) 1 NC_008563.1 recombination and repair protein RecT 1469921 recT 4495683 recT Escherichia coli APEC O1 recombination and repair protein RecT YP_852512.1 1469055 R 405955 CDS YP_852513.1 117623600 4495684 complement(1469857..1472457) 1 NC_008563.1 The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC.; exonuclease VIII 1472457 recE 4495684 recE Escherichia coli APEC O1 exonuclease VIII YP_852513.1 1469857 R 405955 CDS YP_852514.1 117623601 4495685 complement(1472559..1472882) 1 NC_008563.1 Rac prophage hypothetical protein; hypothetical protein 1472882 racC 4495685 racC Escherichia coli APEC O1 hypothetical protein YP_852514.1 1472559 R 405955 CDS YP_852515.1 117623602 4495686 1473608..1474219 1 NC_008563.1 prophage CP-933R superinfection exclusion protein 1474219 sieB 4495686 sieB Escherichia coli APEC O1 prophage CP-933R superinfection exclusion protein YP_852515.1 1473608 D 405955 CDS YP_852516.1 117623603 4495687 complement(1474820..1475239) 1 NC_008563.1 regulator 1475239 4495687 APECO1_503 Escherichia coli APEC O1 regulator YP_852516.1 1474820 R 405955 CDS YP_852517.1 117623604 4495688 1475575..1475997 1 NC_008563.1 Rac prophage hypothetical protein 1475997 ydaT 4495688 ydaT Escherichia coli APEC O1 Rac prophage hypothetical protein YP_852517.1 1475575 D 405955 CDS YP_852518.1 117623605 4495689 1476010..1476870 1 NC_008563.1 hypothetical protein 1476870 4495689 APECO1_505 Escherichia coli APEC O1 hypothetical protein YP_852518.1 1476010 D 405955 CDS YP_852519.1 117623606 4495690 1476877..1477623 1 NC_008563.1 replication protein 1477623 ydaV 4495690 ydaV Escherichia coli APEC O1 replication protein YP_852519.1 1476877 D 405955 CDS YP_852520.1 117623607 4492202 1477595..1478407 1 NC_008563.1 transcription regulatory protein 1478407 4492202 APECO1_507 Escherichia coli APEC O1 transcription regulatory protein YP_852520.1 1477595 D 405955 CDS YP_852521.1 117623608 4492203 1478423..1478839 1 NC_008563.1 hypothetical protein 1478839 4492203 APECO1_508 Escherichia coli APEC O1 hypothetical protein YP_852521.1 1478423 D 405955 CDS YP_852522.1 117623609 4492204 1479003..1479689 1 NC_008563.1 hypothetical protein 1479689 4492204 APECO1_509 Escherichia coli APEC O1 hypothetical protein YP_852522.1 1479003 D 405955 CDS YP_852523.1 117623610 4492205 1480490..1480975 1 NC_008563.1 bacteriophage protein 1480975 4492205 APECO1_510 Escherichia coli APEC O1 bacteriophage protein YP_852523.1 1480490 D 405955 CDS YP_852524.1 117623611 4492206 1481483..1482082 1 NC_008563.1 hypothetical protein 1482082 4492206 APECO1_511 Escherichia coli APEC O1 hypothetical protein YP_852524.1 1481483 D 405955 CDS YP_852525.1 117623612 4492207 1482249..1482905 1 NC_008563.1 antitermination protein 1482905 4492207 APECO1_512 Escherichia coli APEC O1 antitermination protein YP_852525.1 1482249 D 405955 CDS YP_852526.1 117623613 4492208 1484111..1484413 1 NC_008563.1 phage lysis protein 1484413 4492208 APECO1_513 Escherichia coli APEC O1 phage lysis protein YP_852526.1 1484111 D 405955 CDS YP_852527.1 117623614 4492209 1484413..1484910 1 NC_008563.1 phage-related lysozyme (muraminidase) 1484910 4492209 APECO1_514 Escherichia coli APEC O1 phage-related lysozyme (muraminidase) YP_852527.1 1484413 D 405955 CDS YP_852528.1 117623615 4492210 1484895..1485371 1 NC_008563.1 hypothetical protein 1485371 4492210 APECO1_515 Escherichia coli APEC O1 hypothetical protein YP_852528.1 1484895 D 405955 CDS YP_852529.1 117623616 4492211 1485509..1486966 1 NC_008563.1 Rac prophage; potassium transporter subunit 1486966 trkG 4492211 trkG Escherichia coli APEC O1 Rac prophage; potassium transporter subunit YP_852529.1 1485509 D 405955 CDS YP_852530.1 117623617 4492212 1487104..1487895 1 NC_008563.1 ParB-like; transcriptional regulator 1487895 4492212 APECO1_517 Escherichia coli APEC O1 transcriptional regulator YP_852530.1 1487104 D 405955 CDS YP_852531.1 117623618 4492213 1487867..1488820 1 NC_008563.1 hypothetical protein 1488820 4492213 APECO1_518 Escherichia coli APEC O1 hypothetical protein YP_852531.1 1487867 D 405955 CDS YP_852532.1 117623619 4492214 1488756..1489007 1 NC_008563.1 hypothetical protein 1489007 4492214 APECO1_519 Escherichia coli APEC O1 hypothetical protein YP_852532.1 1488756 D 405955 CDS YP_852533.1 117623620 4492215 1489347..1490105 1 NC_008563.1 hypothetical protein 1490105 4492215 APECO1_520 Escherichia coli APEC O1 hypothetical protein YP_852533.1 1489347 D 405955 CDS YP_852534.1 117623621 4492216 1490077..1491387 1 NC_008563.1 phage terminase 1491387 4492216 APECO1_521 Escherichia coli APEC O1 phage terminase YP_852534.1 1490077 D 405955 CDS YP_852535.1 117623622 4492217 1491390..1492796 1 NC_008563.1 chemotaxis protein; hypothetical protein 1492796 4492217 APECO1_522 Escherichia coli APEC O1 hypothetical protein YP_852535.1 1491390 D 405955 CDS YP_852536.1 117623623 4492218 1492777..1493892 1 NC_008563.1 hypothetical protein 1493892 4492218 APECO1_523 Escherichia coli APEC O1 hypothetical protein YP_852536.1 1492777 D 405955 CDS YP_852537.1 117623624 4492219 1493925..1494761 1 NC_008563.1 hypothetical protein 1494761 4492219 APECO1_524 Escherichia coli APEC O1 hypothetical protein YP_852537.1 1493925 D 405955 CDS YP_852538.1 117623625 4492220 1494791..1495999 1 NC_008563.1 hypothetical protein 1495999 4492220 APECO1_525 Escherichia coli APEC O1 hypothetical protein YP_852538.1 1494791 D 405955 CDS YP_852539.1 117623626 4493734 1496270..1496665 1 NC_008563.1 hypothetical protein 1496665 4493734 APECO1_526 Escherichia coli APEC O1 hypothetical protein YP_852539.1 1496270 D 405955 CDS YP_852540.1 117623627 4493735 1496662..1497048 1 NC_008563.1 hypothetical protein 1497048 4493735 APECO1_527 Escherichia coli APEC O1 hypothetical protein YP_852540.1 1496662 D 405955 CDS YP_852541.1 117623628 4493736 1497049..1497429 1 NC_008563.1 hypothetical protein 1497429 4493736 APECO1_528 Escherichia coli APEC O1 hypothetical protein YP_852541.1 1497049 D 405955 CDS YP_852542.1 117623629 4493737 1497426..1497818 1 NC_008563.1 hypothetical protein 1497818 4493737 APECO1_529 Escherichia coli APEC O1 hypothetical protein YP_852542.1 1497426 D 405955 CDS YP_852543.1 117623630 4493738 1497845..1498807 1 NC_008563.1 hypothetical protein 1498807 4493738 APECO1_530 Escherichia coli APEC O1 hypothetical protein YP_852543.1 1497845 D 405955 CDS YP_852544.1 117623631 4493739 1498856..1499317 1 NC_008563.1 Rac prophage hypothetical protein 1499317 ydaY 4493739 ydaY Escherichia coli APEC O1 Rac prophage hypothetical protein YP_852544.1 1498856 D 405955 CDS YP_852545.1 117623632 4493740 1499789..1503022 1 NC_008563.1 Rac prophage; tail protein 1503022 ynaA 4493740 ynaA Escherichia coli APEC O1 Rac prophage; tail protein YP_852545.1 1499789 D 405955 CDS YP_852546.1 117623633 4493741 1503015..1503353 1 NC_008563.1 minor tail protein 1503353 4493741 APECO1_533 Escherichia coli APEC O1 minor tail protein YP_852546.1 1503015 D 405955 CDS YP_852547.1 117623634 4493742 1503353..1504051 1 NC_008563.1 minor tail protein 1504051 4493742 APECO1_5332 Escherichia coli APEC O1 minor tail protein YP_852547.1 1503353 D 405955 CDS YP_852548.1 117623635 4493743 1504056..1504799 1 NC_008563.1 tail fiber component K of prophage 1504799 4493743 APECO1_534 Escherichia coli APEC O1 tail fiber component K of prophage YP_852548.1 1504056 D 405955 CDS YP_852549.1 117623636 4493744 1504697..1505344 1 NC_008563.1 tail component of prophage 1505344 4493744 APECO1_535 Escherichia coli APEC O1 tail component of prophage YP_852549.1 1504697 D 405955 CDS YP_852550.1 117623637 4493745 1505405..1508803 1 NC_008563.1 tail component of prophage 1508803 4493745 APECO1_536 Escherichia coli APEC O1 tail component of prophage YP_852550.1 1505405 D 405955 CDS YP_852551.1 117623638 4493746 1508871..1509470 1 NC_008563.1 outer membrane protein of prophage 1509470 4493746 APECO1_537 Escherichia coli APEC O1 outer membrane protein of prophage YP_852551.1 1508871 D 405955 CDS YP_852552.1 117623639 4493747 1509529..1511910 1 NC_008563.1 tail fiber protein 1511910 4493747 APECO1_538 Escherichia coli APEC O1 tail fiber protein YP_852552.1 1509529 D 405955 CDS YP_852553.1 117623640 4493748 1511910..1512191 1 NC_008563.1 hypothetical protein 1512191 4493748 APECO1_539 Escherichia coli APEC O1 hypothetical protein YP_852553.1 1511910 D 405955 CDS YP_852554.1 117623641 4493749 1512201..1512905 1 NC_008563.1 hypothetical protein 1512905 4493749 APECO1_540 Escherichia coli APEC O1 hypothetical protein YP_852554.1 1512201 D 405955 CDS YP_852555.1 117623642 4493750 1512916..1513206 1 NC_008563.1 hypothetical protein 1513206 4493750 APECO1_541 Escherichia coli APEC O1 hypothetical protein YP_852555.1 1512916 D 405955 CDS YP_852556.1 117623643 4493751 1513719..1514432 1 NC_008563.1 cytolethal distending toxin type IV subunit A 1514432 cdtA 4493751 cdtA Escherichia coli APEC O1 cytolethal distending toxin type IV subunit A YP_852556.1 1513719 D 405955 CDS YP_852557.1 117623644 4493752 1514429..1515250 1 NC_008563.1 cytolethal distending toxin type IV subunit B 1515250 cdtB 4493752 cdtB Escherichia coli APEC O1 cytolethal distending toxin type IV subunit B YP_852557.1 1514429 D 405955 CDS YP_852558.1 117623645 4493753 1515247..1515819 1 NC_008563.1 cytolethal distending toxin type IV subunit C 1515819 cdtC 4493753 cdtC Escherichia coli APEC O1 cytolethal distending toxin type IV subunit C YP_852558.1 1515247 D 405955 CDS YP_852559.1 117623646 4492620 complement(1515889..1517373) 1 NC_008563.1 hypothetical protein 1517373 4492620 APECO1_545 Escherichia coli APEC O1 hypothetical protein YP_852559.1 1515889 R 405955 CDS YP_852560.2 162317578 4492621 complement(1517558..1518508) 1 NC_008563.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 1518508 4492621 APECO1_546 Escherichia coli APEC O1 outer membrane protease YP_852560.2 1517558 R 405955 CDS YP_852561.1 117623648 4492622 complement(1518815..1519165) 1 NC_008563.1 hypothetical protein 1519165 4492622 APECO1_547 Escherichia coli APEC O1 hypothetical protein YP_852561.1 1518815 R 405955 CDS YP_852562.1 117623649 4492623 complement(1519398..1519706) 1 NC_008563.1 integrase 1519706 4492623 APECO1_548 Escherichia coli APEC O1 integrase YP_852562.1 1519398 R 405955 CDS YP_852563.1 117623650 4492624 complement(1521673..1522179) 1 NC_008563.1 filament protein 1522179 4492624 APECO1_549 Escherichia coli APEC O1 filament protein YP_852563.1 1521673 R 405955 CDS YP_852564.1 117623651 4492625 complement(1522248..1523381) 1 NC_008563.1 outer membrane pore protein N, non-specific 1523381 ompN 4492625 ompN Escherichia coli APEC O1 outer membrane pore protein N, non-specific YP_852564.1 1522248 R 405955 CDS YP_852565.1 117623652 4492626 complement(1523747..1527271) 1 NC_008563.1 pyruvate-flavodoxin oxidoreductase 1527271 ydbK 4492626 ydbK Escherichia coli APEC O1 pyruvate-flavodoxin oxidoreductase YP_852565.1 1523747 R 405955 CDS YP_852566.1 117623653 4492627 complement(1527342..1527782) 1 NC_008563.1 hypothetical protein 1527782 4492627 APECO1_552 Escherichia coli APEC O1 hypothetical protein YP_852566.1 1527342 R 405955 CDS YP_852567.1 117623654 4492628 complement(1527808..1528230) 1 NC_008563.1 heat-inducible protein 1528230 hslJ 4492628 hslJ Escherichia coli APEC O1 heat-inducible protein YP_852567.1 1527808 R 405955 CDS YP_852568.1 117623655 4492629 complement(1528341..1529330) 1 NC_008563.1 D-lactate dehydrogenase 1529330 ldhA 4492629 ldhA Escherichia coli APEC O1 D-lactate dehydrogenase YP_852568.1 1528341 R 405955 CDS YP_852569.1 117623656 4492630 1529538..1532177 1 NC_008563.1 hypothetical protein 1532177 ydbH 4492630 ydbH Escherichia coli APEC O1 hypothetical protein YP_852569.1 1529538 D 405955 CDS YP_852570.1 117623657 4492631 1532292..1532693 1 NC_008563.1 hypothetical protein 1532693 ydbL 4492631 ydbL Escherichia coli APEC O1 hypothetical protein YP_852570.1 1532292 D 405955 CDS YP_852571.1 117623658 4492632 1533069..1540061 1 NC_008563.1 EntS/YbdA MFS transporter 1540061 entS 4492632 entS Escherichia coli APEC O1 EntS/YbdA MFS transporter YP_852571.1 1533069 D 405955 CDS YP_852572.1 117623659 4492633 1540281..1541141 1 NC_008563.1 oxidoreductase 1541141 4492633 APECO1_558 Escherichia coli APEC O1 oxidoreductase YP_852572.1 1540281 D 405955 CDS YP_852573.1 117623660 4492634 1541440..1542045 1 NC_008563.1 hypothetical protein 1542045 ynbA 4492634 ynbA Escherichia coli APEC O1 hypothetical protein YP_852573.1 1541440 D 405955 CDS YP_852574.1 117623661 4492635 1542045..1542941 1 NC_008563.1 phosphatidate cytidylyltransferase 1542941 ynbB 4492635 ynbB Escherichia coli APEC O1 phosphatidate cytidylyltransferase YP_852574.1 1542045 D 405955 CDS YP_852575.1 117623662 4492636 1542957..1544714 1 NC_008563.1 methylase 1544714 ynbC 4492636 ynbC Escherichia coli APEC O1 methylase YP_852575.1 1542957 D 405955 CDS YP_852576.1 117623663 4492637 1544629..1546020 1 NC_008563.1 hypothetical protein 1546020 ynbD 4492637 ynbD Escherichia coli APEC O1 hypothetical protein YP_852576.1 1544629 D 405955 CDS YP_852577.1 117623664 4492638 1546005..1546667 1 NC_008563.1 hypothetical protein 1546667 4492638 APECO1_563 Escherichia coli APEC O1 hypothetical protein YP_852577.1 1546005 D 405955 CDS YP_852578.1 117623665 4491656 1546880..1550782 1 NC_008563.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1550782 hrpA 4491656 hrpA Escherichia coli APEC O1 ATP-dependent RNA helicase HrpA YP_852578.1 1546880 D 405955 CDS YP_852579.1 117623666 4491657 1551055..1551855 1 NC_008563.1 hypothetical protein 1551855 ydcF 4491657 ydcF Escherichia coli APEC O1 hypothetical protein YP_852579.1 1551055 D 405955 CDS YP_852580.1 117623667 4491658 1552052..1553491 1 NC_008563.1 NAD-linked; aldehyde dehydrogenase A 1553491 aldA 4491658 aldA Escherichia coli APEC O1 aldehyde dehydrogenase A YP_852580.1 1552052 D 405955 CDS YP_852581.1 117623668 4491659 complement(1553533..1554534) 1 NC_008563.1 glyceraldehyde 3-phosphate dehydrogenase A 1554534 4491659 APECO1_567 Escherichia coli APEC O1 glyceraldehyde 3-phosphate dehydrogenase A YP_852581.1 1553533 R 405955 CDS YP_852582.2 162317577 4491660 1554723..1555253 1 NC_008563.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1555253 cybB 4491660 cybB Escherichia coli APEC O1 cytochrome b561 YP_852582.2 1554723 D 405955 CDS YP_852583.1 117623670 4491661 1555829..1556299 1 NC_008563.1 hypothetical protein 1556299 4491661 APECO1_569 Escherichia coli APEC O1 hypothetical protein YP_852583.1 1555829 D 405955 CDS YP_852584.1 117623671 4491662 complement(1556337..1557401) 1 NC_008563.1 transcriptional regulator YdcI 1557401 ydcI 4491662 ydcI Escherichia coli APEC O1 transcriptional regulator YdcI YP_852584.1 1556337 R 405955 CDS YP_852585.1 117623672 4491663 1557477..1558820 1 NC_008563.1 hypothetical protein 1558820 ydcJ 4491663 ydcJ Escherichia coli APEC O1 hypothetical protein YP_852585.1 1557477 D 405955 CDS YP_852586.1 117623673 4491664 1559045..1560700 1 NC_008563.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1560700 mdoD 4491664 mdoD Escherichia coli APEC O1 glucan biosynthesis protein D YP_852586.1 1559045 D 405955 CDS YP_852587.1 117623674 4491665 1561127..1561666 1 NC_008563.1 ribosomal-protein-L7/L12-serine acetyltransferase 1561666 rimL 4491665 rimL Escherichia coli APEC O1 ribosomal-protein-L7/L12-serine acetyltransferase YP_852587.1 1561127 D 405955 CDS YP_852588.1 117623675 4491666 complement(1561658..1562638) 1 NC_008563.1 hypothetical protein 1562638 ydcK 4491666 ydcK Escherichia coli APEC O1 hypothetical protein YP_852588.1 1561658 R 405955 CDS YP_852589.1 117623676 4491668 1562654..1563754 1 NC_008563.1 potassium-tellurite ethidium and proflavin transporter 1563754 tehA 4491668 tehA Escherichia coli APEC O1 potassium-tellurite ethidium and proflavin transporter YP_852589.1 1562654 D 405955 CDS YP_852590.1 117623677 4491669 1563751..1564344 1 NC_008563.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1564344 tehB 4491669 tehB Escherichia coli APEC O1 tellurite resistance protein TehB YP_852590.1 1563751 D 405955 CDS YP_852591.1 117623678 4491670 1564647..1565315 1 NC_008563.1 hypothetical protein 1565315 4491670 APECO1_577 Escherichia coli APEC O1 hypothetical protein YP_852591.1 1564647 D 405955 CDS YP_852592.1 117623679 4491671 complement(1565350..1566645) 1 NC_008563.1 hypothetical protein 1566645 ydcO 4491671 ydcO Escherichia coli APEC O1 hypothetical protein YP_852592.1 1565350 R 405955 CDS YP_852593.1 117623680 4491672 1566614..1567150 1 NC_008563.1 hypothetical protein 1567150 ydcN 4491672 ydcN Escherichia coli APEC O1 hypothetical protein YP_852593.1 1566614 D 405955 CDS YP_852594.1 117623681 4491673 1567181..1569184 1 NC_008563.1 protease YdcP 1569184 ydcP 4491673 ydcP Escherichia coli APEC O1 protease YdcP YP_852594.1 1567181 D 405955 CDS YP_852595.1 117623682 4491674 1570000..1571406 1 NC_008563.1 fused DNA-binding transcriptional regulator/ amino transferase 1571406 ydcR 4491674 ydcR Escherichia coli APEC O1 fused DNA-binding transcriptional regulator/ amino transferase YP_852595.1 1570000 D 405955 CDS YP_852596.1 117623683 4491675 1571651..1572796 1 NC_008563.1 ABC transporter substrate-binding protein 1572796 ydcS 4491675 ydcS Escherichia coli APEC O1 ABC transporter substrate-binding protein YP_852596.1 1571651 D 405955 CDS YP_852597.1 117623684 4494894 1572814..1573827 1 NC_008563.1 ABC transporter ATP-binding protein 1573827 ydcT 4494894 ydcT Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_852597.1 1572814 D 405955 CDS YP_852598.1 117623685 4494895 1573828..1574769 1 NC_008563.1 ABC transporter permease 1574769 ydcU 4494895 ydcU Escherichia coli APEC O1 ABC transporter permease YP_852598.1 1573828 D 405955 CDS YP_852599.1 117623686 4494896 1574759..1575553 1 NC_008563.1 transport system permease 1575553 4494896 APECO1_585 Escherichia coli APEC O1 transport system permease YP_852599.1 1574759 D 405955 CDS YP_852600.1 117623687 4494897 1575575..1576999 1 NC_008563.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1576999 ydcW 4494897 ydcW Escherichia coli APEC O1 gamma-aminobutyraldehyde dehydrogenase YP_852600.1 1575575 D 405955 CDS YP_852601.1 117623688 4494898 complement(1577188..1577466) 1 NC_008563.1 hypothetical protein 1577466 4494898 APECO1_587 Escherichia coli APEC O1 hypothetical protein YP_852601.1 1577188 R 405955 CDS YP_852602.1 117623689 4494899 complement(1577879..1578328) 1 NC_008563.1 hypothetical protein 1578328 ydcZ 4494899 ydcZ Escherichia coli APEC O1 hypothetical protein YP_852602.1 1577879 R 405955 CDS YP_852603.1 117623690 4494900 complement(1578325..1578843) 1 NC_008563.1 acyltransferase 1578843 yncA 4494900 yncA Escherichia coli APEC O1 acyltransferase YP_852603.1 1578325 R 405955 CDS YP_852604.1 117623691 4494901 1578836..1579177 1 NC_008563.1 hypothetical protein 1579177 4494901 APECO1_590 Escherichia coli APEC O1 hypothetical protein YP_852604.1 1578836 D 405955 CDS YP_852605.1 117623692 4494902 complement(1579324..1581426) 1 NC_008563.1 iron outer membrane transporter 1581426 yncD 4494902 yncD Escherichia coli APEC O1 iron outer membrane transporter YP_852605.1 1579324 R 405955 CDS YP_852606.1 117623693 4494903 1581668..1582729 1 NC_008563.1 hypothetical protein 1582729 yncE 4494903 yncE Escherichia coli APEC O1 hypothetical protein YP_852606.1 1581668 D 405955 CDS YP_852607.1 117623694 4494904 complement(1582842..1584386) 1 NC_008563.1 L-asparagine permease 1584386 ansP 4494904 ansP Escherichia coli APEC O1 L-asparagine permease YP_852607.1 1582842 R 405955 CDS YP_852608.1 117623695 4494905 1584798..1585208 1 NC_008563.1 hypothetical protein 1585208 4494905 APECO1_594 Escherichia coli APEC O1 hypothetical protein YP_852608.1 1584798 D 405955 CDS YP_852609.1 117623696 4494906 1585749..1586033 1 NC_008563.1 hypothetical protein 1586033 4494906 APECO1_595 Escherichia coli APEC O1 hypothetical protein YP_852609.1 1585749 D 405955 CDS YP_852610.1 117623697 4494907 1586052..1588457 1 NC_008563.1 hypothetical protein 1588457 4494907 APECO1_596 Escherichia coli APEC O1 hypothetical protein YP_852610.1 1586052 D 405955 CDS YP_852611.1 117623698 4494908 1588417..1589208 1 NC_008563.1 hypothetical protein 1589208 4494908 APECO1_597 Escherichia coli APEC O1 hypothetical protein YP_852611.1 1588417 D 405955 CDS YP_852612.1 117623699 4494909 1589261..1589980 1 NC_008563.1 hypothetical protein 1589980 4494909 APECO1_598 Escherichia coli APEC O1 hypothetical protein YP_852612.1 1589261 D 405955 CDS YP_852613.1 117623700 4494910 complement(1590911..1591480) 1 NC_008563.1 hypothetical protein 1591480 yddH 4494910 yddH Escherichia coli APEC O1 hypothetical protein YP_852613.1 1590911 R 405955 CDS YP_852614.1 117623701 4494911 1591655..1592500 1 NC_008563.1 N-hydroxyarylamine O-acetyltransferase 1592500 nhoA 4494911 nhoA Escherichia coli APEC O1 N-hydroxyarylamine O-acetyltransferase YP_852614.1 1591655 D 405955 CDS YP_852615.1 117623702 4494912 complement(1592596..1593489) 1 NC_008563.1 hypothetical protein 1593489 yddE 4494912 yddE Escherichia coli APEC O1 hypothetical protein YP_852615.1 1592596 R 405955 CDS YP_852616.1 117623703 4494388 complement(1593569..1594249) 1 NC_008563.1 respiratory nitrate reductase 2 gamma chain 1594249 narV 4494388 narV Escherichia coli APEC O1 respiratory nitrate reductase 2 gamma chain YP_852616.1 1593569 R 405955 CDS YP_852617.1 117623704 4494389 complement(1594246..1594941) 1 NC_008563.1 cryptic nitrate reductase 2 subunit delta 1594941 narW 4494389 narW Escherichia coli APEC O1 cryptic nitrate reductase 2 subunit delta YP_852617.1 1594246 R 405955 CDS YP_852618.1 117623705 4494390 complement(1594941..1596485) 1 NC_008563.1 cryptic nitrate reductase 2 subunit beta 1596485 narY 4494390 narY Escherichia coli APEC O1 cryptic nitrate reductase 2 subunit beta YP_852618.1 1594941 R 405955 CDS YP_852619.1 117623706 4494391 complement(1596482..1600345) 1 NC_008563.1 respiratory nitrate reductase 2 alpha chain 1600345 narZ 4494391 narZ Escherichia coli APEC O1 respiratory nitrate reductase 2 alpha chain YP_852619.1 1596482 R 405955 CDS YP_852620.1 117623707 4494392 complement(1600317..1601723) 1 NC_008563.1 nitrite extrusion protein 2 1601723 narU 4494392 narU Escherichia coli APEC O1 nitrite extrusion protein 2 YP_852620.1 1600317 R 405955 CDS YP_852621.1 117623708 4494393 complement(1601978..1602859) 1 NC_008563.1 hypothetical protein 1602859 4494393 APECO1_607 Escherichia coli APEC O1 hypothetical protein YP_852621.1 1601978 R 405955 CDS YP_852622.1 117623709 4494394 complement(1603265..1604335) 1 NC_008563.1 hypothetical protein 1604335 4494394 APECO1_608 Escherichia coli APEC O1 hypothetical protein YP_852622.1 1603265 R 405955 CDS YP_852623.1 117623710 4494395 1603727..1606138 1 NC_008563.1 FdnG subunit alpha of formate dehydrogenase-N 1606138 fdnG 4494395 fdnG Escherichia coli APEC O1 FdnG subunit alpha of formate dehydrogenase-N YP_852623.1 1603727 D 405955 CDS YP_852625.1 117623712 4494397 1607010..1607681 1 NC_008563.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1607681 fdnI 4494397 fdnI Escherichia coli APEC O1 formate dehydrogenase-N subunit gamma YP_852625.1 1607010 D 405955 CDS YP_852626.1 117623713 4494398 complement(1607910..1608194) 1 NC_008563.1 hypothetical protein 1608194 4494398 APECO1_612 Escherichia coli APEC O1 hypothetical protein YP_852626.1 1607910 R 405955 CDS YP_852627.1 117623714 4494399 complement(1608194..1608472) 1 NC_008563.1 addiction system protein; hypothetical protein 1608472 4494399 APECO1_613 Escherichia coli APEC O1 hypothetical protein YP_852627.1 1608194 R 405955 CDS YP_852628.1 117623715 4494400 complement(1608658..1609698) 1 NC_008563.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1609698 adhP 4494400 adhP Escherichia coli APEC O1 alcohol dehydrogenase YP_852628.1 1608658 R 405955 CDS YP_852629.2 229775972 4494401 complement(1609802..1611499) 1 NC_008563.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1611499 sfcA 4494401 sfcA Escherichia coli APEC O1 malate dehydrogenase YP_852629.2 1609802 R 405955 CDS YP_852630.1 117623717 4494402 complement(1611894..1612172) 1 NC_008563.1 biofilm-dependent modulation protein 1612172 4494402 APECO1_616 Escherichia coli APEC O1 biofilm-dependent modulation protein YP_852630.1 1611894 R 405955 CDS YP_852631.1 117623718 4494403 1612454..1612885 1 NC_008563.1 osmotically inducible protein OsmC 1612885 osmC 4494403 osmC Escherichia coli APEC O1 osmotically inducible protein OsmC YP_852631.1 1612454 D 405955 CDS YP_852632.1 117623719 4494404 complement(1613075..1615498) 1 NC_008563.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1615498 4494404 APECO1_618 Escherichia coli APEC O1 cAMP phosphodiesterase YP_852632.1 1613075 R 405955 CDS YP_852633.1 117623720 4494405 complement(1616041..1617360) 1 NC_008563.1 lipoprotein YddW precursor 1617360 yddW 4494405 yddW Escherichia coli APEC O1 lipoprotein YddW precursor YP_852633.1 1616041 R 405955 CDS YP_852634.1 117623721 4494406 complement(1617491..1619026) 1 NC_008563.1 amino acid antiporter 1619026 xasA 4494406 xasA Escherichia coli APEC O1 amino acid antiporter YP_852634.1 1617491 R 405955 CDS YP_852635.1 117623722 4494407 complement(1619182..1620474) 1 NC_008563.1 glutamate decarboxylase 1620474 gadA 4494407 gadA Escherichia coli APEC O1 glutamate decarboxylase YP_852635.1 1619182 R 405955 CDS YP_852636.1 117623723 4493754 complement(1620943..1623738) 1 NC_008563.1 zinc protease PqqL 1623738 pqqL 4493754 pqqL Escherichia coli APEC O1 zinc protease PqqL YP_852636.1 1620943 R 405955 CDS YP_852637.1 117623724 4493755 complement(1623783..1626155) 1 NC_008563.1 hypothetical protein 1626155 yddB 4493755 yddB Escherichia coli APEC O1 hypothetical protein YP_852637.1 1623783 R 405955 CDS YP_852638.1 117623725 4493756 complement(1626193..1627878) 1 NC_008563.1 ATP-binding component of a transport system 1627878 yddA 4493756 yddA Escherichia coli APEC O1 ATP-binding component of a transport system YP_852638.1 1626193 R 405955 CDS YP_852639.1 117623726 4493757 complement(1628169..1629326) 1 NC_008563.1 hypothetical protein 1629326 ydeM 4493757 ydeM Escherichia coli APEC O1 hypothetical protein YP_852639.1 1628169 R 405955 CDS YP_852640.1 117623727 4493758 complement(1629378..1631060) 1 NC_008563.1 sulfatase 1631060 ydeN 4493758 ydeN Escherichia coli APEC O1 sulfatase YP_852640.1 1629378 R 405955 CDS YP_852641.1 117623728 4493759 complement(1631462..1632223) 1 NC_008563.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1632223 4493759 APECO1_627 Escherichia coli APEC O1 transcriptional regulator YdeO YP_852641.1 1631462 R 405955 CDS YP_852642.1 117623729 4493760 complement(1632743..1635022) 1 NC_008563.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase 1635022 ydeP 4493760 ydeP Escherichia coli APEC O1 oxidoreductase YP_852642.1 1632743 R 405955 CDS YP_852643.1 117623730 4493761 complement(1635361..1636275) 1 NC_008563.1 Fml fimbrial adhesin FmlD 1636275 fmlD 4493761 fmlD Escherichia coli APEC O1 Fml fimbrial adhesin FmlD YP_852643.1 1635361 R 405955 CDS YP_852644.1 117623731 4493762 complement(1636335..1636838) 1 NC_008563.1 fimbrial-like adhesin protein 1636838 ydeR 4493762 ydeR Escherichia coli APEC O1 fimbrial-like adhesin protein YP_852644.1 1636335 R 405955 CDS YP_852645.1 117623732 4493763 complement(1636851..1637381) 1 NC_008563.1 fimbrial-like adhesin protein 1637381 ydeS 4493763 ydeS Escherichia coli APEC O1 fimbrial-like adhesin protein YP_852645.1 1636851 R 405955 CDS YP_852646.1 117623733 4493764 complement(1637395..1640046) 1 NC_008563.1 outer membrane usher protein FimD 1640046 4493764 APECO1_632 Escherichia coli APEC O1 outer membrane usher protein FimD YP_852646.1 1637395 R 405955 CDS YP_852647.1 117623734 4493765 complement(1640088..1640807) 1 NC_008563.1 chaperone protein fimC precursor 1640807 4493765 APECO1_633 Escherichia coli APEC O1 chaperone protein fimC precursor YP_852647.1 1640088 R 405955 CDS YP_852648.1 117623735 4493766 complement(1641160..1641723) 1 NC_008563.1 Fml fimbriae subunit 1641723 fmlA 4493766 fmlA Escherichia coli APEC O1 Fml fimbriae subunit YP_852648.1 1641160 R 405955 CDS YP_852649.1 117623736 4493767 complement(1642499..1643281) 1 NC_008563.1 hypothetical protein 1643281 4493767 APECO1_635 Escherichia coli APEC O1 hypothetical protein YP_852649.1 1642499 R 405955 CDS YP_852650.1 117623737 4493768 1643391..1643648 1 NC_008563.1 hypothetical protein 1643648 4493768 APECO1_636 Escherichia coli APEC O1 hypothetical protein YP_852650.1 1643391 D 405955 CDS YP_852651.1 117623738 4493769 complement(1643907..1645286) 1 NC_008563.1 regulator with HipB 1645286 hipA 4493769 hipA Escherichia coli APEC O1 regulator with HipB YP_852651.1 1643907 R 405955 CDS YP_852652.1 117623739 4493770 complement(1645229..1645495) 1 NC_008563.1 DNA-binding transcriptional regulator HipB 1645495 hipB 4493770 hipB Escherichia coli APEC O1 DNA-binding transcriptional regulator HipB YP_852652.1 1645229 R 405955 CDS YP_852653.1 117623740 4493771 1645803..1646561 1 NC_008563.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1646561 tam 4493771 tam Escherichia coli APEC O1 trans-aconitate 2-methyltransferase YP_852653.1 1645803 D 405955 CDS YP_852654.1 117623741 4493772 complement(1646565..1647530) 1 NC_008563.1 hypothetical protein 1647530 4493772 APECO1_640 Escherichia coli APEC O1 hypothetical protein YP_852654.1 1646565 R 405955 CDS YP_852655.1 117623742 4493398 complement(1647676..1649127) 1 NC_008563.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1649127 uxaB 4493398 uxaB Escherichia coli APEC O1 altronate oxidoreductase YP_852655.1 1647676 R 405955 CDS YP_852656.1 117623743 4493399 complement(1649354..1650772) 1 NC_008563.1 hypothetical protein 1650772 yneF 4493399 yneF Escherichia coli APEC O1 hypothetical protein YP_852656.1 1649354 R 405955 CDS YP_852657.1 117623744 4493400 complement(1650911..1651270) 1 NC_008563.1 hypothetical protein 1651270 yneG 4493400 yneG Escherichia coli APEC O1 hypothetical protein YP_852657.1 1650911 R 405955 CDS YP_852658.1 117623745 4493401 complement(1651270..1652196) 1 NC_008563.1 catalyzes the formation of glutamate from glutamine; glutaminase 1652196 yneH 4493401 yneH Escherichia coli APEC O1 glutaminase YP_852658.1 1651270 R 405955 CDS YP_852659.1 117623746 4493402 complement(1652260..1653672) 1 NC_008563.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1653672 yneI 4493402 yneI Escherichia coli APEC O1 succinate semialdehyde dehydrogenase YP_852659.1 1652260 R 405955 CDS YP_852660.1 117623747 4493403 1653749..1654630 1 NC_008563.1 aldehyde-dehydrogenase like protein YneI 1654630 yneJ 4493403 yneJ Escherichia coli APEC O1 aldehyde-dehydrogenase like protein YneI YP_852660.1 1653749 D 405955 CDS YP_852661.1 117623748 4493404 1654969..1656159 1 NC_008563.1 sugar efflux transporter 1656159 sotB 4493404 sotB Escherichia coli APEC O1 sugar efflux transporter YP_852661.1 1654969 D 405955 CDS YP_852662.1 117623749 4493405 complement(1656184..1656849) 1 NC_008563.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1656849 marC 4493405 marC Escherichia coli APEC O1 multiple drug resistance protein MarC YP_852662.1 1656184 R 405955 CDS YP_852663.1 117623750 4493406 1657061..1657495 1 NC_008563.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1657495 marR 4493406 marR Escherichia coli APEC O1 DNA-binding transcriptional repressor MarR YP_852663.1 1657061 D 405955 CDS YP_852664.1 117623751 4493407 1657510..1657899 1 NC_008563.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1657899 marA 4493407 marA Escherichia coli APEC O1 DNA-binding transcriptional activator MarA YP_852664.1 1657510 D 405955 CDS YP_852665.1 117623752 4493408 complement(1658206..1659675) 1 NC_008563.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 1659675 celA 4493408 celA Escherichia coli APEC O1 6-phospho-beta-glucosidase YP_852665.1 1658206 R 405955 CDS YP_852666.1 117623753 4493409 complement(1659669..1661342) 1 NC_008563.1 outer membrane protein YieC 1661342 yieC 4493409 yieC Escherichia coli APEC O1 outer membrane protein YieC YP_852666.1 1659669 R 405955 CDS YP_852667.1 117623754 4493410 complement(1661397..1661711) 1 NC_008563.1 PTS system cellobiose-specific transporter subunit IIA 1661711 4493410 APECO1_652 Escherichia coli APEC O1 PTS system cellobiose-specific transporter subunit IIA YP_852667.1 1661397 R 405955 CDS YP_852668.1 117623755 4493411 complement(1661736..1663058) 1 NC_008563.1 hypothetical protein 1663058 4493411 APECO1_653 Escherichia coli APEC O1 hypothetical protein YP_852668.1 1661736 R 405955 CDS YP_852669.1 117623756 4493412 complement(1663173..1663484) 1 NC_008563.1 PTS system cellobiose-specific transporter subunit IIB 1663484 4493412 APECO1_654 Escherichia coli APEC O1 PTS system cellobiose-specific transporter subunit IIB YP_852669.1 1663173 R 405955 CDS YP_852670.1 117623757 4493413 1663683..1664381 1 NC_008563.1 transcriptional regulator 1664381 4493413 APECO1_655 Escherichia coli APEC O1 transcriptional regulator YP_852670.1 1663683 D 405955 CDS YP_852671.2 229775971 4493414 complement(1664426..1665325) 1 NC_008563.1 O-acetylserine/cysteine export protein 1665325 ydeD 4493414 ydeD Escherichia coli APEC O1 O-acetylserine/cysteine export protein YP_852671.2 1664426 R 405955 CDS YP_852672.1 117623759 4493415 1665520..1666707 1 NC_008563.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1666707 ydeE 4493415 ydeE Escherichia coli APEC O1 MFS-type transporter YdeE YP_852672.1 1665520 D 405955 CDS YP_852673.1 117623760 4493416 complement(1667148..1668044) 1 NC_008563.1 hypothetical protein 1668044 ydeH 4493416 ydeH Escherichia coli APEC O1 hypothetical protein YP_852673.1 1667148 R 405955 CDS YP_852674.1 117623761 4493417 complement(1668546..1670591) 1 NC_008563.1 dipeptidyl carboxypeptidase II 1670591 dcp 4493417 dcp Escherichia coli APEC O1 dipeptidyl carboxypeptidase II YP_852674.1 1668546 R 405955 CDS YP_852675.1 117623762 4494369 1670728..1671474 1 NC_008563.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1671474 ydfG 4494369 ydfG Escherichia coli APEC O1 3-hydroxy acid dehydrogenase YP_852675.1 1670728 D 405955 CDS YP_852676.1 117623763 4494370 1671563..1672249 1 NC_008563.1 hypothetical protein 1672249 4494370 APECO1_660 Escherichia coli APEC O1 hypothetical protein YP_852676.1 1671563 D 405955 CDS YP_852678.1 117623765 4494372 complement(1672665..1674125) 1 NC_008563.1 oxidoreductase 1674125 4494372 APECO1_662 Escherichia coli APEC O1 oxidoreductase YP_852678.1 1672665 R 405955 CDS YP_852679.2 229775970 4494373 complement(1674626..1675645) 1 NC_008563.1 dehydrogenase 1675645 rspB 4494373 rspB Escherichia coli APEC O1 dehydrogenase YP_852679.2 1674626 R 405955 CDS YP_852680.1 117623767 4494374 complement(1675657..1676904) 1 NC_008563.1 starvation sensing protein RspA 1676904 rspA 4494374 rspA Escherichia coli APEC O1 starvation sensing protein RspA YP_852680.1 1675657 R 405955 CDS YP_852681.1 117623768 4494375 complement(1677077..1677412) 1 NC_008563.1 hypothetical protein 1677412 ynfA 4494375 ynfA Escherichia coli APEC O1 hypothetical protein YP_852681.1 1677077 R 405955 CDS YP_852682.1 117623769 4494376 1677538..1677879 1 NC_008563.1 hypothetical protein 1677879 ynfB 4494376 ynfB Escherichia coli APEC O1 hypothetical protein YP_852682.1 1677538 D 405955 CDS YP_852683.1 117623770 4494377 1677914..1678474 1 NC_008563.1 spermidine N1-acetyltransferase 1678474 4494377 APECO1_667 Escherichia coli APEC O1 spermidine N1-acetyltransferase YP_852683.1 1677914 D 405955 CDS YP_852684.1 117623771 4494378 complement(1678477..1679223) 1 NC_008563.1 hypothetical protein 1679223 ynfC 4494378 ynfC Escherichia coli APEC O1 hypothetical protein YP_852684.1 1678477 R 405955 CDS YP_852685.1 117623772 4494379 1679253..1679600 1 NC_008563.1 hypothetical protein 1679600 ynfD 4494379 ynfD Escherichia coli APEC O1 hypothetical protein YP_852685.1 1679253 D 405955 CDS YP_852686.1 117623773 4494380 1679799..1682225 1 NC_008563.1 dimethyl sulfoxide reductase subunit YnfE 1682225 ynfE 4494380 ynfE Escherichia coli APEC O1 dimethyl sulfoxide reductase subunit YnfE YP_852686.1 1679799 D 405955 CDS YP_852687.1 117623774 4494381 1682283..1684709 1 NC_008563.1 dimethyl sulfoxide reductase subunit YnfF 1684709 ynfF 4494381 ynfF Escherichia coli APEC O1 dimethyl sulfoxide reductase subunit YnfF YP_852687.1 1682283 D 405955 CDS YP_852688.1 117623775 4494382 1684720..1685337 1 NC_008563.1 dimethyl sulfoxide reductase, anaerobic subunit B 1685337 dmsB 4494382 dmsB Escherichia coli APEC O1 dimethyl sulfoxide reductase, anaerobic subunit B YP_852688.1 1684720 D 405955 CDS YP_852689.1 117623776 4494383 1685099..1686193 1 NC_008563.1 oxidoreductase, membrane subunit 1686193 ynfH 4494383 ynfH Escherichia coli APEC O1 oxidoreductase, membrane subunit YP_852689.1 1685099 D 405955 CDS YP_852690.1 117623777 4494384 1686227..1686850 1 NC_008563.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1686850 ynfI 4494384 ynfI Escherichia coli APEC O1 twin-argninine leader-binding protein DmsD YP_852690.1 1686227 D 405955 CDS YP_852691.1 117623778 4494385 1686988..1688229 1 NC_008563.1 voltage-gated ClC-type chloride channel ClcB 1688229 ynfJ 4494385 ynfJ Escherichia coli APEC O1 voltage-gated ClC-type chloride channel ClcB YP_852691.1 1686988 D 405955 CDS YP_852692.1 117623779 4494386 complement(1688182..1688889) 1 NC_008563.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1688889 ynfK 4494386 ynfK Escherichia coli APEC O1 dithiobiotin synthetase YP_852692.1 1688182 R 405955 CDS YP_852693.1 117623780 4494387 complement(1689002..1690222) 1 NC_008563.1 Mlc protein 1690222 mlc 4494387 mlc Escherichia coli APEC O1 Mlc protein YP_852693.1 1689002 R 405955 CDS YP_852694.1 117623781 4492086 complement(1690357..1691250) 1 NC_008563.1 transcriptional regulator 1691250 ynfL 4492086 ynfL Escherichia coli APEC O1 transcriptional regulator YP_852694.1 1690357 R 405955 CDS YP_852695.1 117623782 4492087 1691357..1692610 1 NC_008563.1 transporter 1692610 ynfM 4492087 ynfM Escherichia coli APEC O1 transporter YP_852695.1 1691357 D 405955 CDS YP_852696.1 117623783 4492088 1693008..1693343 1 NC_008563.1 required for growth and survival under moderately acid conditions; acid shock protein 1693343 asr 4492088 asr Escherichia coli APEC O1 acid shock protein YP_852696.1 1693008 D 405955 CDS YP_852697.1 117623784 4492089 1693619..1694440 1 NC_008563.1 protease 1694440 ydgD 4492089 ydgD Escherichia coli APEC O1 protease YP_852697.1 1693619 D 405955 CDS YP_852698.1 117623785 4492090 complement(1694479..1694808) 1 NC_008563.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1694808 4492090 APECO1_682 Escherichia coli APEC O1 multidrug efflux system protein MdtI YP_852698.1 1694479 R 405955 CDS YP_852699.1 117623786 4492091 complement(1694795..1695160) 1 NC_008563.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1695160 ydgF 4492091 ydgF Escherichia coli APEC O1 multidrug efflux system protein MdtJ YP_852699.1 1694795 R 405955 CDS YP_852700.1 117623787 4492092 1695571..1696605 1 NC_008563.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1696605 tqsA 4492092 tqsA Escherichia coli APEC O1 transporter YP_852700.1 1695571 D 405955 CDS YP_852701.1 117623788 4492093 complement(1696630..1698018) 1 NC_008563.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1698018 pntB 4492093 pntB Escherichia coli APEC O1 pyridine nucleotide transhydrogenase YP_852701.1 1696630 R 405955 CDS YP_852702.1 117623789 4492094 complement(1698029..1699615) 1 NC_008563.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1699615 pntA 4492094 pntA Escherichia coli APEC O1 NAD(P) transhydrogenase subunit alpha YP_852702.1 1698029 R 405955 CDS YP_852703.1 117623790 4492095 1700085..1701029 1 NC_008563.1 hypothetical protein 1701029 ydgH 4492095 ydgH Escherichia coli APEC O1 hypothetical protein YP_852703.1 1700085 D 405955 CDS YP_852704.1 117623791 4492096 1701215..1702597 1 NC_008563.1 arginine/ornithine antiporter 1702597 ydgI 4492096 ydgI Escherichia coli APEC O1 arginine/ornithine antiporter YP_852704.1 1701215 D 405955 CDS YP_852705.1 117623792 4492097 1702634..1703356 1 NC_008563.1 short chain dehydrogenase 1703356 ydgB 4492097 ydgB Escherichia coli APEC O1 short chain dehydrogenase YP_852705.1 1702634 D 405955 CDS YP_852706.1 117623793 4492098 complement(1703353..1703688) 1 NC_008563.1 hypothetical protein 1703688 ydgC 4492098 ydgC Escherichia coli APEC O1 hypothetical protein YP_852706.1 1703353 R 405955 CDS YP_852707.1 117623794 4492099 1703781..1704536 1 NC_008563.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1704536 rstA 4492099 rstA Escherichia coli APEC O1 DNA-binding transcriptional regulator RstA YP_852707.1 1703781 D 405955 CDS YP_852708.1 117623795 4492100 1704540..1705841 1 NC_008563.1 sensor protein RstB 1705841 rstB 4492100 rstB Escherichia coli APEC O1 sensor protein RstB YP_852708.1 1704540 D 405955 CDS YP_852709.1 117623796 4492101 1705905..1706846 1 NC_008563.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1706846 tus 4492101 tus Escherichia coli APEC O1 DNA replication terminus site-binding protein YP_852709.1 1705905 D 405955 CDS YP_852710.1 117623797 4492102 complement(1706843..1708246) 1 NC_008563.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1708246 fumC 4492102 fumC Escherichia coli APEC O1 fumarate hydratase YP_852710.1 1706843 R 405955 CDS YP_852711.1 117623798 4493645 complement(1708389..1710035) 1 NC_008563.1 fumarate hydratase, aerobic class I 1710035 fumA 4493645 fumA Escherichia coli APEC O1 fumarate hydratase, aerobic class I YP_852711.1 1708389 R 405955 CDS YP_852712.1 117623799 4493646 1710234..1711409 1 NC_008563.1 mannose-6-phosphate isomerase 1711409 manA 4493646 manA Escherichia coli APEC O1 mannose-6-phosphate isomerase YP_852712.1 1710234 D 405955 CDS YP_852713.1 117623800 4493647 1711510..1713018 1 NC_008563.1 hypothetical protein 1713018 4493647 APECO1_697 Escherichia coli APEC O1 hypothetical protein YP_852713.1 1711510 D 405955 CDS YP_852714.1 117623801 4493648 complement(1713063..1714328) 1 NC_008563.1 outer membrane porin protein 1714328 uidC 4493648 uidC Escherichia coli APEC O1 outer membrane porin protein YP_852714.1 1713063 R 405955 CDS YP_852715.1 117623802 4493649 complement(1714367..1715740) 1 NC_008563.1 glucuronide transporter 1715740 uidB 4493649 uidB Escherichia coli APEC O1 glucuronide transporter YP_852715.1 1714367 R 405955 CDS YP_852716.1 117623803 4493650 complement(1715737..1717548) 1 NC_008563.1 beta-D-glucuronidase 1717548 uidA 4493650 uidA Escherichia coli APEC O1 beta-D-glucuronidase YP_852716.1 1715737 R 405955 CDS YP_852717.1 117623804 4493651 complement(1717938..1718528) 1 NC_008563.1 repressor for uid operon 1718528 uidR 4493651 uidR Escherichia coli APEC O1 repressor for uid operon YP_852717.1 1717938 R 405955 CDS YP_852718.1 117623805 4493652 complement(1718757..1719524) 1 NC_008563.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1719524 hdhA 4493652 hdhA Escherichia coli APEC O1 7-alpha-hydroxysteroid dehydrogenase YP_852718.1 1718757 R 405955 CDS YP_852719.1 117623806 4493653 complement(1719636..1720664) 1 NC_008563.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1720664 malI 4493653 malI Escherichia coli APEC O1 DNA-binding transcriptional repressor MalI YP_852719.1 1719636 R 405955 CDS YP_852720.1 117623807 4493654 1720839..1722431 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1722431 malX 4493654 malX Escherichia coli APEC O1 bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_852720.1 1720839 D 405955 CDS YP_852721.1 117623808 4493655 1722441..1723613 1 NC_008563.1 bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon 1723613 malY 4493655 malY Escherichia coli APEC O1 bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon YP_852721.1 1722441 D 405955 CDS YP_852722.1 117623809 4493656 1723717..1724718 1 NC_008563.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1724718 add 4493656 add Escherichia coli APEC O1 adenosine deaminase YP_852722.1 1723717 D 405955 CDS YP_852723.1 117623810 4493657 complement(1724754..1725833) 1 NC_008563.1 oxidoreductase 1725833 ydgJ 4493657 ydgJ Escherichia coli APEC O1 oxidoreductase YP_852723.1 1724754 R 405955 CDS YP_852724.1 117623811 4493658 1726251..1726514 1 NC_008563.1 hypothetical protein 1726514 4493658 APECO1_708 Escherichia coli APEC O1 hypothetical protein YP_852724.1 1726251 D 405955 CDS YP_852725.1 117623812 4493659 1726736..1727176 1 NC_008563.1 hypothetical protein 1727176 ydgK 4493659 ydgK Escherichia coli APEC O1 hypothetical protein YP_852725.1 1726736 D 405955 CDS YP_852726.1 117623813 4493660 1727253..1727834 1 NC_008563.1 Na(+)-translocating NADH-quinone reductase subunit E 1727834 rnfA 4493660 rnfA Escherichia coli APEC O1 Na(+)-translocating NADH-quinone reductase subunit E YP_852726.1 1727253 D 405955 CDS YP_852727.1 117623814 4493661 1727834..1728412 1 NC_008563.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1728412 rnfB 4493661 rnfB Escherichia coli APEC O1 electron transport complex protein RnfB YP_852727.1 1727834 D 405955 CDS YP_852728.1 117623815 4493662 1728405..1730531 1 NC_008563.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1730531 rnfC 4493662 rnfC Escherichia coli APEC O1 electron transport complex protein RnfC YP_852728.1 1728405 D 405955 CDS YP_852729.1 117623816 4493663 1730532..1731590 1 NC_008563.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1731590 rnfD 4493663 rnfD Escherichia coli APEC O1 electron transport complex protein RnfD YP_852729.1 1730532 D 405955 CDS YP_852730.1 117623817 4491616 1731594..1732214 1 NC_008563.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1732214 rnfG 4491616 rnfG Escherichia coli APEC O1 electron transport complex protein RnfG YP_852730.1 1731594 D 405955 CDS YP_852731.1 117623818 4491617 1732218..1732913 1 NC_008563.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1732913 rnfE 4491617 rnfE Escherichia coli APEC O1 electron transport complex protein RsxE YP_852731.1 1732218 D 405955 CDS YP_852732.1 117623819 4491618 1732913..1733548 1 NC_008563.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1733548 nth 4491618 nth Escherichia coli APEC O1 endonuclease III YP_852732.1 1732913 D 405955 CDS YP_852733.1 117623820 4491619 1734159..1735661 1 NC_008563.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1735661 tppB 4491619 tppB Escherichia coli APEC O1 tripeptide transporter permease YP_852733.1 1734159 D 405955 CDS YP_852734.1 117623821 4491620 1735766..1736371 1 NC_008563.1 glutathionine S-transferase 1736371 gst 4491620 gst Escherichia coli APEC O1 glutathionine S-transferase YP_852734.1 1735766 D 405955 CDS YP_852735.1 117623822 4491621 complement(1736415..1737278) 1 NC_008563.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1737278 pdxY 4491621 pdxY Escherichia coli APEC O1 pyridoxamine kinase YP_852735.1 1736415 R 405955 CDS YP_852736.1 117623823 4491622 complement(1737337..1738623) 1 NC_008563.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1738623 tyrS 4491622 tyrS Escherichia coli APEC O1 tyrosyl-tRNA synthetase YP_852736.1 1737337 R 405955 CDS YP_852737.1 117623824 4491623 complement(1738740..1739396) 1 NC_008563.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1739396 pdxH 4491623 pdxH Escherichia coli APEC O1 pyridoxamine 5'-phosphate oxidase YP_852737.1 1738740 R 405955 CDS YP_852738.1 117623825 4491624 complement(1739455..1739784) 1 NC_008563.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1739784 ydhA 4491624 ydhA Escherichia coli APEC O1 lysozyme inhibitor YP_852738.1 1739455 R 405955 CDS YP_852739.1 117623826 4491625 complement(1739882..1740991) 1 NC_008563.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1740991 anmK 4491625 anmK Escherichia coli APEC O1 anhydro-N-acetylmuramic acid kinase YP_852739.1 1739882 R 405955 CDS YP_852740.1 117623827 4491626 1741265..1741732 1 NC_008563.1 outer membrane lipoprotein SlyB 1741732 slyB 4491626 slyB Escherichia coli APEC O1 outer membrane lipoprotein SlyB YP_852740.1 1741265 D 405955 CDS YP_852741.1 117623828 4491627 complement(1741779..1742219) 1 NC_008563.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1742219 slyA 4491627 slyA Escherichia coli APEC O1 transcriptional regulator SlyA YP_852741.1 1741779 R 405955 CDS YP_852742.1 117623829 4491628 1742644..1743387 1 NC_008563.1 hypothetical protein 1743387 ydhJ 4491628 ydhJ Escherichia coli APEC O1 hypothetical protein YP_852742.1 1742644 D 405955 CDS YP_852743.1 117623830 4491629 1743509..1745521 1 NC_008563.1 hypothetical protein 1745521 ydhK 4491629 ydhK Escherichia coli APEC O1 hypothetical protein YP_852743.1 1743509 D 405955 CDS YP_852744.1 117623831 4491630 complement(1745522..1746094) 1 NC_008563.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1746094 sodC 4491630 sodC Escherichia coli APEC O1 superoxide dismutase YP_852744.1 1745522 R 405955 CDS YP_852745.1 117623832 4491631 complement(1746124..1747020) 1 NC_008563.1 oxidoreductase YdhF 1747020 ydhF 4491631 ydhF Escherichia coli APEC O1 oxidoreductase YdhF YP_852745.1 1746124 R 405955 CDS YP_852746.1 117623833 4491632 1747411..1748010 1 NC_008563.1 DNA-binding transcriptional regulator 1748010 ydhM 4491632 ydhM Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_852746.1 1747411 D 405955 CDS YP_852747.1 117623834 4491633 1748047..1749144 1 NC_008563.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1749144 nemA 4491633 nemA Escherichia coli APEC O1 N-ethylmaleimide reductase YP_852747.1 1748047 D 405955 CDS YP_852748.1 117623835 4491634 1749225..1749632 1 NC_008563.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1749632 gloA 4491634 gloA Escherichia coli APEC O1 glyoxalase I YP_852748.1 1749225 D 405955 CDS YP_852749.1 117623836 4491635 1749735..1750382 1 NC_008563.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1750382 rnt 4491635 rnt Escherichia coli APEC O1 ribonuclease T YP_852749.1 1749735 D 405955 CDS YP_852750.1 117623837 4492259 complement(1750754..1751101) 1 NC_008563.1 hypothetical protein 1751101 ydhO 4492259 ydhO Escherichia coli APEC O1 hypothetical protein YP_852750.1 1750754 R 405955 CDS YP_852751.1 117623838 4492260 1752379..1752960 1 NC_008563.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1752960 sodB 4492260 sodB Escherichia coli APEC O1 superoxide dismutase YP_852751.1 1752379 D 405955 CDS YP_852752.1 117623839 4492261 complement(1753106..1754275) 1 NC_008563.1 transporter 1754275 ydhP 4492261 ydhP Escherichia coli APEC O1 transporter YP_852752.1 1753106 R 405955 CDS YP_852753.1 117623840 4492262 1754829..1755854 1 NC_008563.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1755854 purR 4492262 purR Escherichia coli APEC O1 DNA-binding transcriptional repressor PurR YP_852753.1 1754829 D 405955 CDS YP_852754.1 117623841 4492263 complement(1755851..1756783) 1 NC_008563.1 DNA-binding transcriptional regulator 1756783 ydhB 4492263 ydhB Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_852754.1 1755851 R 405955 CDS YP_852755.1 117623842 4492264 1756896..1758107 1 NC_008563.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1758107 ydhC 4492264 ydhC Escherichia coli APEC O1 inner membrane transport protein YdhC YP_852755.1 1756896 D 405955 CDS YP_852756.1 117623843 4492265 1758398..1759546 1 NC_008563.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1759546 cfa 4492265 cfa Escherichia coli APEC O1 cyclopropane-fatty-acyl-phospholipid synthase YP_852756.1 1758398 D 405955 CDS YP_852757.1 117623844 4492266 complement(1759586..1760227) 1 NC_008563.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1760227 ribE 4492266 ribE Escherichia coli APEC O1 riboflavin synthase subunit alpha YP_852757.1 1759586 R 405955 CDS YP_852758.1 117623845 4492267 1760442..1761815 1 NC_008563.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1761815 mdtK 4492267 mdtK Escherichia coli APEC O1 multidrug efflux protein YP_852758.1 1760442 D 405955 CDS YP_852759.1 117623846 4492268 complement(1761856..1763112) 1 NC_008563.1 hypothetical protein 1763112 ydhQ 4492268 ydhQ Escherichia coli APEC O1 hypothetical protein YP_852759.1 1761856 R 405955 CDS YP_852761.1 117623848 4492270 1764117..1765067 1 NC_008563.1 hypothetical protein 1765067 ydhS 4492270 ydhS Escherichia coli APEC O1 hypothetical protein YP_852761.1 1764117 D 405955 CDS YP_852762.1 117623849 4492271 1765368..1765721 1 NC_008563.1 hypothetical protein 1765721 4492271 APECO1_747 Escherichia coli APEC O1 hypothetical protein YP_852762.1 1765368 D 405955 CDS YP_852763.1 117623850 4492272 complement(1765733..1766545) 1 NC_008563.1 hypothetical protein 1766545 ydhT 4492272 ydhT Escherichia coli APEC O1 hypothetical protein YP_852763.1 1765733 R 405955 CDS YP_852764.1 117623851 4492273 complement(1766549..1767334) 1 NC_008563.1 cytochrome 1767334 ydhU 4492273 ydhU Escherichia coli APEC O1 cytochrome YP_852764.1 1766549 R 405955 CDS YP_852765.1 117623852 4492274 complement(1767331..1768050) 1 NC_008563.1 oxidoreductase Fe-S subunit 1768050 4492274 APECO1_750 Escherichia coli APEC O1 oxidoreductase Fe-S subunit YP_852765.1 1767331 R 405955 CDS YP_852766.1 117623853 4492275 complement(1768063..1768710) 1 NC_008563.1 hypothetical protein 1768710 ydhW 4492275 ydhW Escherichia coli APEC O1 hypothetical protein YP_852766.1 1768063 R 405955 CDS YP_852767.2 229775969 4492276 complement(1768714..1770816) 1 NC_008563.1 oxidoreductase 1770816 ydhV 4492276 ydhV Escherichia coli APEC O1 oxidoreductase YP_852767.2 1768714 R 405955 CDS YP_852768.1 117623855 4492277 complement(1770837..1771463) 1 NC_008563.1 hypothetical protein 1771463 ydhY 4492277 ydhY Escherichia coli APEC O1 hypothetical protein YP_852768.1 1770837 R 405955 CDS YP_852769.1 117623856 4493418 1772469..1774097 1 NC_008563.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1774097 pykF 4493418 pykF Escherichia coli APEC O1 pyruvate kinase YP_852769.1 1772469 D 405955 CDS YP_852770.1 117623857 4493420 complement(1774707..1775711) 1 NC_008563.1 hypothetical protein 1775711 ynhG 4493420 ynhG Escherichia coli APEC O1 hypothetical protein YP_852770.1 1774707 R 405955 CDS YP_852771.1 117623858 4493421 complement(1775860..1776276) 1 NC_008563.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1776276 sufE 4493421 sufE Escherichia coli APEC O1 cysteine desufuration protein SufE YP_852771.1 1775860 R 405955 CDS YP_852772.1 117623859 4493422 complement(1776289..1777509) 1 NC_008563.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1777509 sufS 4493422 sufS Escherichia coli APEC O1 bifunctional cysteine desulfurase/selenocysteine lyase YP_852772.1 1776289 R 405955 CDS YP_852773.1 117623860 4493423 complement(1777506..1778777) 1 NC_008563.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1778777 sufD 4493423 sufD Escherichia coli APEC O1 cysteine desulfurase activator complex subunit SufD YP_852773.1 1777506 R 405955 CDS YP_852774.1 117623861 4493424 complement(1778752..1779498) 1 NC_008563.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 1779498 sufC 4493424 sufC Escherichia coli APEC O1 cysteine desulfurase YP_852774.1 1778752 R 405955 CDS YP_852775.1 117623862 4493425 complement(1779508..1781034) 1 NC_008563.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1781034 sufB 4493425 sufB Escherichia coli APEC O1 cysteine desulfurase activator complex subunit SufB YP_852775.1 1779508 R 405955 CDS YP_852776.1 117623863 4493426 complement(1781004..1781372) 1 NC_008563.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1781372 sufA 4493426 sufA Escherichia coli APEC O1 iron-sulfur cluster assembly scaffold protein YP_852776.1 1781004 R 405955 CDS YP_852777.1 117623864 4493427 complement(1781921..1782190) 1 NC_008563.1 hypothetical protein 1782190 ydiH 4493427 ydiH Escherichia coli APEC O1 hypothetical protein YP_852777.1 1781921 R 405955 CDS YP_852778.1 117623865 4493428 complement(1782209..1782619) 1 NC_008563.1 hypothetical protein 1782619 ydiI 4493428 ydiI Escherichia coli APEC O1 hypothetical protein YP_852778.1 1782209 R 405955 CDS YP_852779.1 117623866 4493429 complement(1782616..1785672) 1 NC_008563.1 FAD-linked oxidoreductase 1785672 ydiJ 4493429 ydiJ Escherichia coli APEC O1 FAD-linked oxidoreductase YP_852779.1 1782616 R 405955 CDS YP_852780.1 117623867 4493430 1785886..1786998 1 NC_008563.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; hypothetical protein 1786998 4493430 APECO1_765 Escherichia coli APEC O1 hypothetical protein YP_852780.1 1785886 D 405955 CDS YP_852781.1 117623868 4493431 1787883..1789097 1 NC_008563.1 transporter 1789097 ydiM 4493431 ydiM Escherichia coli APEC O1 transporter YP_852781.1 1787883 D 405955 CDS YP_852782.1 117623869 4493432 1789318..1790589 1 NC_008563.1 transporter 1790589 ydiN 4493432 ydiN Escherichia coli APEC O1 transporter YP_852782.1 1789318 D 405955 CDS YP_852783.1 117623870 4493433 1790601..1791467 1 NC_008563.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1791467 ydiB 4493433 ydiB Escherichia coli APEC O1 quinate/shikimate dehydrogenase YP_852783.1 1790601 D 405955 CDS YP_852784.1 117623871 4493434 1791498..1792256 1 NC_008563.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1792256 aroD 4493434 aroD Escherichia coli APEC O1 3-dehydroquinate dehydratase YP_852784.1 1791498 D 405955 CDS YP_852785.1 117623872 4493435 1792402..1793997 1 NC_008563.1 fused acetyl-CoA:acetoacetyl-CoA transferase 1793997 ydiF 4493435 ydiF Escherichia coli APEC O1 fused acetyl-CoA:acetoacetyl-CoA transferase YP_852785.1 1792402 D 405955 CDS YP_852786.2 162317576 4493436 1794011..1795162 1 NC_008563.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1795162 ydiO 4493436 ydiO Escherichia coli APEC O1 acyl-CoA dehydrogenase YP_852786.2 1794011 D 405955 CDS YP_852787.1 117623874 4493437 complement(1795205..1796116) 1 NC_008563.1 DNA-binding transcriptional regulator 1796116 ydiP 4493437 ydiP Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_852787.1 1795205 R 405955 CDS YP_852788.1 117623875 4492036 1796411..1797196 1 NC_008563.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1797196 ydiQ 4492036 ydiQ Escherichia coli APEC O1 electron transfer flavoprotein YdiQ YP_852788.1 1796411 D 405955 CDS YP_852789.1 117623876 4492037 1797216..1798154 1 NC_008563.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1798154 ydiR 4492037 ydiR Escherichia coli APEC O1 electron transfer flavoprotein subunit YdiR YP_852789.1 1797216 D 405955 CDS YP_852790.1 117623877 4492038 1798209..1799498 1 NC_008563.1 hypothetical protein 1799498 ydiS 4492038 ydiS Escherichia coli APEC O1 hypothetical protein YP_852790.1 1798209 D 405955 CDS YP_852791.1 117623878 4492039 1799495..1799788 1 NC_008563.1 4Fe-4S ferredoxin 1799788 ydiT 4492039 ydiT Escherichia coli APEC O1 4Fe-4S ferredoxin YP_852791.1 1799495 D 405955 CDS YP_852792.1 117623879 4492040 1799791..1801491 1 NC_008563.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1801491 ydiD 4492040 ydiD Escherichia coli APEC O1 short chain acyl-CoA synthetase YP_852792.1 1799791 D 405955 CDS YP_852793.1 117623880 4492041 complement(1801548..1803926) 1 NC_008563.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1803926 pps 4492041 pps Escherichia coli APEC O1 phosphoenolpyruvate synthase YP_852793.1 1801548 R 405955 CDS YP_852794.1 117623881 4492042 1804259..1805092 1 NC_008563.1 hypothetical protein 1805092 4492042 APECO1_779 Escherichia coli APEC O1 hypothetical protein YP_852794.1 1804259 D 405955 CDS YP_852795.1 117623882 4492043 1805249..1806295 1 NC_008563.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1806295 aroH 4492043 aroH Escherichia coli APEC O1 phospho-2-dehydro-3-deoxyheptonate aldolase YP_852795.1 1805249 D 405955 CDS YP_852796.1 117623883 4492044 complement(1806622..1808058) 1 NC_008563.1 hypothetical protein 1808058 ydiU 4492044 ydiU Escherichia coli APEC O1 hypothetical protein YP_852796.1 1806622 R 405955 CDS YP_852797.1 117623884 4492045 complement(1808121..1808834) 1 NC_008563.1 hypothetical protein 1808834 ydiV 4492045 ydiV Escherichia coli APEC O1 hypothetical protein YP_852797.1 1808121 R 405955 CDS YP_852798.1 117623885 4492046 complement(1809081..1809545) 1 NC_008563.1 lipoprotein 1809545 nlpC 4492046 nlpC Escherichia coli APEC O1 lipoprotein YP_852798.1 1809081 R 405955 CDS YP_852799.1 117623886 4492047 complement(1809623..1810372) 1 NC_008563.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1810372 btuC 4492047 btuC Escherichia coli APEC O1 vitamin B12-transporter ATPase YP_852799.1 1809623 R 405955 CDS YP_852800.1 117623887 4492048 complement(1810372..1810923) 1 NC_008563.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 1810923 btuE 4492048 btuE Escherichia coli APEC O1 glutathione peroxidase YP_852800.1 1810372 R 405955 CDS YP_852801.1 117623888 4492049 complement(1810985..1811965) 1 NC_008563.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1811965 btuC 4492049 btuC Escherichia coli APEC O1 vtamin B12-transporter permease YP_852801.1 1810985 R 405955 CDS YP_852802.1 117623889 4492050 complement(1812370..1814757) 1 NC_008563.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1814757 pheT 4492050 pheT Escherichia coli APEC O1 phenylalanyl-tRNA synthetase subunit beta YP_852802.1 1812370 R 405955 CDS YP_852803.2 162317575 4492051 complement(1814772..1815755) 1 NC_008563.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1815755 pheS 4492051 pheS Escherichia coli APEC O1 phenylalanyl-tRNA synthetase subunit alpha YP_852803.2 1814772 R 405955 CDS YP_852804.1 117623891 4492052 complement(1816206..1816562) 1 NC_008563.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1816562 rplT 4492052 rplT Escherichia coli APEC O1 50S ribosomal protein L20 YP_852804.1 1816206 R 405955 CDS YP_852806.1 117623893 4492054 complement(1817455..1819383) 1 NC_008563.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1819383 thrS 4492054 thrS Escherichia coli APEC O1 threonyl-tRNA synthetase YP_852806.1 1817455 R 405955 CDS YP_852807.1 117623894 4494428 1819906..1820340 1 NC_008563.1 hypothetical protein 1820340 4494428 APECO1_792 Escherichia coli APEC O1 hypothetical protein YP_852807.1 1819906 D 405955 CDS YP_852808.1 117623895 4494429 complement(1821267..1822025) 1 NC_008563.1 hypothetical protein 1822025 ydiY 4494429 ydiY Escherichia coli APEC O1 hypothetical protein YP_852808.1 1821267 R 405955 CDS YP_852809.1 117623896 4494430 1822308..1823240 1 NC_008563.1 6-phosphofructokinase 1823240 pfkB 4494430 pfkB Escherichia coli APEC O1 6-phosphofructokinase YP_852809.1 1822308 D 405955 CDS YP_852810.1 117623897 4494431 1823341..1823631 1 NC_008563.1 hypothetical protein 1823631 ydiZ 4494431 ydiZ Escherichia coli APEC O1 hypothetical protein YP_852810.1 1823341 D 405955 CDS YP_852811.1 117623898 4494432 1823737..1824597 1 NC_008563.1 phosphotransferase/kinase 1824597 yniA 4494432 yniA Escherichia coli APEC O1 phosphotransferase/kinase YP_852811.1 1823737 D 405955 CDS YP_852812.1 117623899 4494433 complement(1824638..1825174) 1 NC_008563.1 hypothetical protein 1825174 yniB 4494433 yniB Escherichia coli APEC O1 hypothetical protein YP_852812.1 1824638 R 405955 CDS YP_852813.1 117623900 4494434 1825321..1825989 1 NC_008563.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1825989 yniC 4494434 yniC Escherichia coli APEC O1 2-deoxyglucose-6-phosphatase YP_852813.1 1825321 D 405955 CDS YP_852814.1 117623901 4494435 1826141..1826743 1 NC_008563.1 hypothetical protein 1826743 ydjM 4494435 ydjM Escherichia coli APEC O1 hypothetical protein YP_852814.1 1826141 D 405955 CDS YP_852815.1 117623902 4494436 1826876..1828267 1 NC_008563.1 symporter protein YdjN 1828267 ydjN 4494436 ydjN Escherichia coli APEC O1 symporter protein YdjN YP_852815.1 1826876 D 405955 CDS YP_852816.1 117623903 4494437 complement(1828314..1828577) 1 NC_008563.1 cell division modulator 1828577 cedA 4494437 cedA Escherichia coli APEC O1 cell division modulator YP_852816.1 1828314 R 405955 CDS YP_852817.1 117623904 4494438 1828760..1831021 1 NC_008563.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1831021 katE 4494438 katE Escherichia coli APEC O1 hydroperoxidase II YP_852817.1 1828760 D 405955 CDS YP_852818.1 117623905 4494439 complement(1831067..1831825) 1 NC_008563.1 hypothetical protein 1831825 ydjC 4494439 ydjC Escherichia coli APEC O1 hypothetical protein YP_852818.1 1831067 R 405955 CDS YP_852819.1 117623906 4494440 complement(1831838..1833190) 1 NC_008563.1 6-phospho-beta-glucosidase 1833190 celF 4494440 celF Escherichia coli APEC O1 6-phospho-beta-glucosidase YP_852819.1 1831838 R 405955 CDS YP_852820.1 117623907 4494441 complement(1833294..1834136) 1 NC_008563.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1834136 celD 4494441 celD Escherichia coli APEC O1 DNA-binding transcriptional regulator ChbR YP_852820.1 1833294 R 405955 CDS YP_852821.1 117623908 4494442 complement(1834144..1834494) 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1834494 celC 4494442 celC Escherichia coli APEC O1 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_852821.1 1834144 R 405955 CDS YP_852822.1 117623909 4494443 complement(1834545..1835903) 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1835903 celB 4494443 celB Escherichia coli APEC O1 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_852822.1 1834545 R 405955 CDS YP_852823.1 117623910 4494444 complement(1835988..1836308) 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1836308 celA 4494444 celA Escherichia coli APEC O1 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_852823.1 1835988 R 405955 CDS YP_852824.1 117623911 4494445 complement(1836607..1836945) 1 NC_008563.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1836945 osmE 4494445 osmE Escherichia coli APEC O1 DNA-binding transcriptional activator OsmE YP_852824.1 1836607 R 405955 CDS YP_852825.1 117623912 4494446 1837147..1837974 1 NC_008563.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1837974 nadE 4494446 nadE Escherichia coli APEC O1 NAD synthetase YP_852825.1 1837147 D 405955 CDS YP_852826.1 117623913 4494447 1838204..1839091 1 NC_008563.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1839091 thrL 4494447 thrL Escherichia coli APEC O1 nucleotide excision repair endonuclease YP_852826.1 1838204 D 405955 CDS YP_852827.1 117623914 4495250 complement(1839051..1839626) 1 NC_008563.1 hypothetical protein 1839626 ydjR 4495250 ydjR Escherichia coli APEC O1 hypothetical protein YP_852827.1 1839051 R 405955 CDS YP_852828.1 117623915 4495251 complement(1839829..1840314) 1 NC_008563.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1840314 spy 4495251 spy Escherichia coli APEC O1 hypothetical protein YP_852828.1 1839829 R 405955 CDS YP_852829.1 117623916 4495252 complement(1840644..1841612) 1 NC_008563.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1841612 ydjS 4495252 ydjS Escherichia coli APEC O1 succinylglutamate desuccinylase YP_852829.1 1840644 R 405955 CDS YP_852830.1 117623917 4495253 complement(1841605..1842948) 1 NC_008563.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1842948 astB 4495253 astB Escherichia coli APEC O1 succinylarginine dihydrolase YP_852830.1 1841605 R 405955 CDS YP_852831.1 117623918 4495254 complement(1842945..1844132) 1 NC_008563.1 succinylglutamic semialdehyde dehydrogenase 1844132 thrL 4495254 thrL Escherichia coli APEC O1 succinylglutamic semialdehyde dehydrogenase YP_852831.1 1842945 R 405955 CDS YP_852832.1 117623919 4495255 complement(1844419..1845453) 1 NC_008563.1 arginine succinyltransferase 1845453 astA 4495255 astA Escherichia coli APEC O1 arginine succinyltransferase YP_852832.1 1844419 R 405955 CDS YP_852833.1 117623920 4495256 complement(1845450..1846670) 1 NC_008563.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1846670 cstC 4495256 cstC Escherichia coli APEC O1 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_852833.1 1845450 R 405955 CDS YP_852834.1 117623921 4495257 1847104..1847922 1 NC_008563.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1847922 xthA 4495257 xthA Escherichia coli APEC O1 exonuclease III YP_852834.1 1847104 D 405955 CDS YP_852835.1 117623922 4495258 1848089..1848799 1 NC_008563.1 hypothetical protein 1848799 ydjX 4495258 ydjX Escherichia coli APEC O1 hypothetical protein YP_852835.1 1848089 D 405955 CDS YP_852836.1 117623923 4495259 1848642..1849481 1 NC_008563.1 hypothetical protein 1849481 ydjY 4495259 ydjY Escherichia coli APEC O1 hypothetical protein YP_852836.1 1848642 D 405955 CDS YP_852837.1 117623924 4495260 1849495..1850202 1 NC_008563.1 hypothetical protein 1850202 ydjZ 4495260 ydjZ Escherichia coli APEC O1 hypothetical protein YP_852837.1 1849495 D 405955 CDS YP_852838.1 117623925 4495261 1850202..1850750 1 NC_008563.1 hypothetical protein 1850750 ynjA 4495261 ynjA Escherichia coli APEC O1 hypothetical protein YP_852838.1 1850202 D 405955 CDS YP_852839.1 117623926 4495262 1850760..1851926 1 NC_008563.1 ABC transporter substrate-binding protein 1851926 ynjB 4495262 ynjB Escherichia coli APEC O1 ABC transporter substrate-binding protein YP_852839.1 1850760 D 405955 CDS YP_852840.1 117623927 4495263 1851899..1853434 1 NC_008563.1 ABC transporter permease 1853434 ynjC 4495263 ynjC Escherichia coli APEC O1 ABC transporter permease YP_852840.1 1851899 D 405955 CDS YP_852841.1 117623928 4495264 1853347..1854087 1 NC_008563.1 ABC transporter ATP-binding protein 1854087 ynjD 4495264 ynjD Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_852841.1 1853347 D 405955 CDS YP_852842.1 117623929 4495265 1854139..1855461 1 NC_008563.1 thiosulfate sulfurtransferase YnjE 1855461 ynjE 4495265 ynjE Escherichia coli APEC O1 thiosulfate sulfurtransferase YnjE YP_852842.1 1854139 D 405955 CDS YP_852843.1 117623930 4495266 complement(1855470..1856096) 1 NC_008563.1 hypothetical protein 1856096 ynjF 4495266 ynjF Escherichia coli APEC O1 hypothetical protein YP_852843.1 1855470 R 405955 CDS YP_852844.1 117623931 4495267 1856177..1856584 1 NC_008563.1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1856584 ynjG 4495267 ynjG Escherichia coli APEC O1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_852844.1 1856177 D 405955 CDS YP_852845.1 117623932 4495268 complement(1856550..1856822) 1 NC_008563.1 hypothetical protein 1856822 ynjH 4495268 ynjH Escherichia coli APEC O1 hypothetical protein YP_852845.1 1856550 R 405955 CDS YP_852846.1 117623933 4491997 1857058..1858401 1 NC_008563.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1858401 gdhA 4491997 gdhA Escherichia coli APEC O1 glutamate dehydrogenase YP_852846.1 1857058 D 405955 CDS YP_852847.1 117623934 4491998 complement(1858478..1860487) 1 NC_008563.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1860487 topB 4491998 topB Escherichia coli APEC O1 DNA topoisomerase III YP_852847.1 1858478 R 405955 CDS YP_852848.1 117623935 4491999 complement(1860438..1861487) 1 NC_008563.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1861487 selD 4491999 selD Escherichia coli APEC O1 selenophosphate synthetase YP_852848.1 1860438 R 405955 CDS YP_852849.2 229775968 4492000 complement(1861598..1862149) 1 NC_008563.1 hypothetical protein 1862149 ydjA 4492000 ydjA Escherichia coli APEC O1 hypothetical protein YP_852849.2 1861598 R 405955 CDS YP_852850.1 117623937 4492001 1862310..1864166 1 NC_008563.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1864166 sppA 4492001 sppA Escherichia coli APEC O1 protease 4 YP_852850.1 1862310 D 405955 CDS YP_852851.1 117623938 4492002 1864333..1865349 1 NC_008563.1 converts asparagine to aspartate and ammonia; asparaginase 1865349 ansA 4492002 ansA Escherichia coli APEC O1 asparaginase YP_852851.1 1864333 D 405955 CDS YP_852852.1 117623939 4492003 1865342..1866001 1 NC_008563.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1866001 ydjB 4492003 ydjB Escherichia coli APEC O1 nicotinamidase/pyrazinamidase YP_852852.1 1865342 D 405955 CDS YP_852853.1 117623940 4492004 complement(1866094..1867521) 1 NC_008563.1 metabolite transport protein 1867521 ydjE 4492004 ydjE Escherichia coli APEC O1 metabolite transport protein YP_852853.1 1866094 R 405955 CDS YP_852854.1 117623941 4492005 complement(1867570..1868328) 1 NC_008563.1 Z2808; DEOR-type transcriptional regulator 1868328 4492005 APECO1_839 Escherichia coli APEC O1 DEOR-type transcriptional regulator YP_852854.1 1867570 R 405955 CDS YP_852855.1 117623942 4492006 complement(1868465..1869445) 1 NC_008563.1 oxidoreductase 1869445 ydjG 4492006 ydjG Escherichia coli APEC O1 oxidoreductase YP_852855.1 1868465 R 405955 CDS YP_852856.1 117623943 4492007 complement(1869455..1870222) 1 NC_008563.1 sugar kinase 1870222 ydjH 4492007 ydjH Escherichia coli APEC O1 sugar kinase YP_852856.1 1869455 R 405955 CDS YP_852857.1 117623944 4492008 complement(1870406..1871242) 1 NC_008563.1 hypothetical protein 1871242 ydjI 4492008 ydjI Escherichia coli APEC O1 hypothetical protein YP_852857.1 1870406 R 405955 CDS YP_852858.1 117623945 4492009 complement(1871263..1872306) 1 NC_008563.1 zinc-type alcohol dehydrogenase-like protein 1872306 ydjJ 4492009 ydjJ Escherichia coli APEC O1 zinc-type alcohol dehydrogenase-like protein YP_852858.1 1871263 R 405955 CDS YP_852859.1 117623946 4492010 complement(1872323..1873702) 1 NC_008563.1 metabolite transport protein 1873702 ydjK 4492010 ydjK Escherichia coli APEC O1 metabolite transport protein YP_852859.1 1872323 R 405955 CDS YP_852860.1 117623947 4492011 complement(1873729..1874805) 1 NC_008563.1 oxidoreductase 1874805 ydjL 4492011 ydjL Escherichia coli APEC O1 oxidoreductase YP_852860.1 1873729 R 405955 CDS YP_852861.1 117623948 4492012 complement(1875489..1875932) 1 NC_008563.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1875932 yeaA 4492012 yeaA Escherichia coli APEC O1 methionine sulfoxide reductase B YP_852861.1 1875489 R 405955 CDS YP_852862.1 117623949 4492013 1876235..1877239 1 NC_008563.1 glyceraldehyde 3-phosphate dehydrogenase A 1877239 gapA 4492013 gapA Escherichia coli APEC O1 glyceraldehyde 3-phosphate dehydrogenase A YP_852862.1 1876235 D 405955 CDS YP_852863.1 117623950 4492014 1877302..1878207 1 NC_008563.1 hypothetical protein 1878207 yeaD 4492014 yeaD Escherichia coli APEC O1 hypothetical protein YP_852863.1 1877302 D 405955 CDS YP_852864.1 117623951 4492015 complement(1878258..1879157) 1 NC_008563.1 hypothetical protein 1879157 yeaE 4492015 yeaE Escherichia coli APEC O1 hypothetical protein YP_852864.1 1878258 R 405955 CDS YP_852865.1 117623952 4492016 complement(1879202..1879948) 1 NC_008563.1 MltA-interacting protein 1879948 yeaF 4492016 yeaF Escherichia coli APEC O1 MltA-interacting protein YP_852865.1 1879202 R 405955 CDS YP_852866.1 117623953 4495406 1880384..1882318 1 NC_008563.1 hypothetical protein 1882318 yeaG 4495406 yeaG Escherichia coli APEC O1 hypothetical protein YP_852866.1 1880384 D 405955 CDS YP_852867.1 117623954 4495407 1882431..1883714 1 NC_008563.1 hypothetical protein 1883714 yeaH 4495407 yeaH Escherichia coli APEC O1 hypothetical protein YP_852867.1 1882431 D 405955 CDS YP_852868.1 117623955 4495409 1883861..1885336 1 NC_008563.1 hypothetical protein 1885336 yeaI 4495409 yeaI Escherichia coli APEC O1 hypothetical protein YP_852868.1 1883861 D 405955 CDS YP_852869.1 117623956 4495410 1885337..1887007 1 NC_008563.1 hypothetical protein 1887007 yeaJ 4495410 yeaJ Escherichia coli APEC O1 hypothetical protein YP_852869.1 1885337 D 405955 CDS YP_852870.1 117623957 4495411 1887050..1887553 1 NC_008563.1 hypothetical protein 1887553 yeaK 4495411 yeaK Escherichia coli APEC O1 hypothetical protein YP_852870.1 1887050 D 405955 CDS YP_852871.1 117623958 4495412 complement(1888231..1889052) 1 NC_008563.1 transcriptional regulator 1889052 yeaM 4495412 yeaM Escherichia coli APEC O1 transcriptional regulator YP_852871.1 1888231 R 405955 CDS YP_852872.1 117623959 4495413 1889149..1890330 1 NC_008563.1 transporter 1890330 yeaN 4495413 yeaN Escherichia coli APEC O1 transporter YP_852872.1 1889149 D 405955 CDS YP_852873.2 229775967 4495414 1890385..1890732 1 NC_008563.1 hypothetical protein 1890732 yeaO 4495414 yeaO Escherichia coli APEC O1 hypothetical protein YP_852873.2 1890385 D 405955 CDS YP_852874.1 117623961 4495415 1891191..1892216 1 NC_008563.1 hypothetical protein 1892216 yeaP 4495415 yeaP Escherichia coli APEC O1 hypothetical protein YP_852874.1 1891191 D 405955 CDS YP_852875.1 117623962 4495416 1892897..1893388 1 NC_008563.1 hypothetical protein 1893388 yeaR 4495416 yeaR Escherichia coli APEC O1 hypothetical protein YP_852875.1 1892897 D 405955 CDS YP_852876.1 117623963 4495417 complement(1893597..1894235) 1 NC_008563.1 leucine export protein LeuE 1894235 yeaS 4495417 yeaS Escherichia coli APEC O1 leucine export protein LeuE YP_852876.1 1893597 R 405955 CDS YP_852877.1 117623964 4495418 complement(1894778..1895893) 1 NC_008563.1 ribonuclease D 1895893 rnd 4495418 rnd Escherichia coli APEC O1 ribonuclease D YP_852877.1 1894778 R 405955 CDS YP_852878.1 117623965 4495419 complement(1895975..1897726) 1 NC_008563.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1897726 fadD 4495419 fadD Escherichia coli APEC O1 long-chain-fatty-acid--CoA ligase YP_852878.1 1895975 R 405955 CDS YP_852879.1 117623966 4495420 complement(1897865..1898446) 1 NC_008563.1 lipoprotein 1898446 yeaY 4495420 yeaY Escherichia coli APEC O1 lipoprotein YP_852879.1 1897865 R 405955 CDS YP_852880.1 117623967 4495421 complement(1898486..1899181) 1 NC_008563.1 O-sialoglycoprotein endopeptidase 1899181 yeaZ 4495421 yeaZ Escherichia coli APEC O1 O-sialoglycoprotein endopeptidase YP_852880.1 1898486 R 405955 CDS YP_852881.1 117623968 4495422 complement(1899239..1901149) 1 NC_008563.1 ATP-dependent helicase 1901149 yoaA 4495422 yoaA Escherichia coli APEC O1 ATP-dependent helicase YP_852881.1 1899239 R 405955 CDS YP_852882.1 117623969 4495423 1901233..1901625 1 NC_008563.1 hypothetical protein 1901625 yoaB 4495423 yoaB Escherichia coli APEC O1 hypothetical protein YP_852882.1 1901233 D 405955 CDS YP_852883.1 117623970 4495424 1901987..1902346 1 NC_008563.1 hypothetical protein 1902346 yoaC 4495424 yoaC Escherichia coli APEC O1 hypothetical protein YP_852883.1 1901987 D 405955 CDS YP_852884.1 117623971 4493888 1902719..1904080 1 NC_008563.1 para-aminobenzoate synthase component I 1904080 pabB 4493888 pabB Escherichia coli APEC O1 para-aminobenzoate synthase component I YP_852884.1 1902719 D 405955 CDS YP_852885.1 117623972 4493889 1904084..1904662 1 NC_008563.1 hypothetical protein 1904662 yeaB 4493889 yeaB Escherichia coli APEC O1 hypothetical protein YP_852885.1 1904084 D 405955 CDS YP_852886.1 117623973 4493890 1904846..1906210 1 NC_008563.1 L-serine dehydratase 1 1906210 sdaA 4493890 sdaA Escherichia coli APEC O1 L-serine dehydratase 1 YP_852886.1 1904846 D 405955 CDS YP_852887.1 117623974 4493891 1906332..1907939 1 NC_008563.1 hypothetical protein 1907939 yoaD 4493891 yoaD Escherichia coli APEC O1 hypothetical protein YP_852887.1 1906332 D 405955 CDS YP_852888.1 117623975 4493892 complement(1907943..1909499) 1 NC_008563.1 hypothetical protein 1909499 yoaE 4493892 yoaE Escherichia coli APEC O1 hypothetical protein YP_852888.1 1907943 R 405955 CDS YP_852889.1 117623976 4493893 1909962..1910933 1 NC_008563.1 PTS system mannose-specific transporter subunit IIAB 1910933 manX 4493893 manX Escherichia coli APEC O1 PTS system mannose-specific transporter subunit IIAB YP_852889.1 1909962 D 405955 CDS YP_852890.1 117623977 4493894 1910996..1911796 1 NC_008563.1 mannose-specific enzyme IIC 1911796 manY 4493894 manY Escherichia coli APEC O1 mannose-specific enzyme IIC YP_852890.1 1910996 D 405955 CDS YP_852891.1 117623978 4493895 1911800..1912660 1 NC_008563.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1912660 manZ 4493895 manZ Escherichia coli APEC O1 PTS system mannose-specific transporter subunit IID YP_852891.1 1911800 D 405955 CDS YP_852892.1 117623979 4493896 1912715..1913173 1 NC_008563.1 hypothetical protein 1913173 yobD 4493896 yobD Escherichia coli APEC O1 hypothetical protein YP_852892.1 1912715 D 405955 CDS YP_852893.1 117623980 4493897 1913548..1914168 1 NC_008563.1 membrane protein YebN; hypothetical protein 1914168 yebN 4493897 yebN Escherichia coli APEC O1 hypothetical protein YP_852893.1 1913548 D 405955 CDS YP_852894.1 117623981 4493898 complement(1914165..1914974) 1 NC_008563.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 1914974 rrmA 4493898 rrmA Escherichia coli APEC O1 23S rRNA methyltransferase A YP_852894.1 1914165 R 405955 CDS YP_852895.1 117623982 4493899 1915467..1915730 1 NC_008563.1 hypothetical protein 1915730 4493899 APECO1_880 Escherichia coli APEC O1 hypothetical protein YP_852895.1 1915467 D 405955 CDS YP_852896.1 117623983 4493900 complement(1916176..1916463) 1 NC_008563.1 hypothetical protein 1916463 yebO 4493900 yebO Escherichia coli APEC O1 hypothetical protein YP_852896.1 1916176 R 405955 CDS YP_852897.1 117623984 4493901 complement(1917223..1918014) 1 NC_008563.1 transcriptional regulator 1918014 kdgR 4493901 kdgR Escherichia coli APEC O1 transcriptional regulator YP_852897.1 1917223 R 405955 CDS YP_852898.1 117623985 4493902 1918080..1919564 1 NC_008563.1 transporter 1919564 yebQ 4493902 yebQ Escherichia coli APEC O1 transporter YP_852898.1 1918080 D 405955 CDS YP_852899.1 117623986 4493903 complement(1919610..1920491) 1 NC_008563.1 metalloprotease; heat shock protein HtpX 1920491 htpX 4493903 htpX Escherichia coli APEC O1 heat shock protein HtpX YP_852899.1 1919610 R 405955 CDS YP_852900.1 117623987 4493904 complement(1920683..1922731) 1 NC_008563.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1922731 prc 4493904 prc Escherichia coli APEC O1 carboxy-terminal protease YP_852900.1 1920683 R 405955 CDS YP_852901.1 117623988 4493905 complement(1922751..1923449) 1 NC_008563.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1923449 proQ 4493905 proQ Escherichia coli APEC O1 solute/DNA competence effector YP_852901.1 1922751 R 405955 CDS YP_852902.1 117623989 4493906 1924173..1925456 1 NC_008563.1 hypothetical protein 1925456 yebS 4493906 yebS Escherichia coli APEC O1 hypothetical protein YP_852902.1 1924173 D 405955 CDS YP_852903.1 117623990 4493907 1925419..1928058 1 NC_008563.1 hypothetical protein 1928058 yebT 4493907 yebT Escherichia coli APEC O1 hypothetical protein YP_852903.1 1925419 D 405955 CDS YP_852904.1 117623991 4491921 1928132..1929577 1 NC_008563.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1929577 yebU 4491921 yebU Escherichia coli APEC O1 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_852904.1 1928132 D 405955 CDS YP_852905.1 117623992 4491922 1929952..1930227 1 NC_008563.1 hypothetical protein 1930227 yebW 4491922 yebW Escherichia coli APEC O1 hypothetical protein YP_852905.1 1929952 D 405955 CDS YP_852906.1 117623993 4491923 complement(1930228..1930884) 1 NC_008563.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1930884 pphA 4491923 pphA Escherichia coli APEC O1 serine/threonine protein phosphatase 1 YP_852906.1 1930228 R 405955 CDS YP_852907.1 117623994 4491924 complement(1931279..1931620) 1 NC_008563.1 hypothetical protein 1931620 yebY 4491924 yebY Escherichia coli APEC O1 hypothetical protein YP_852907.1 1931279 R 405955 CDS YP_852908.1 117623995 4491925 complement(1931633..1932505) 1 NC_008563.1 hypothetical protein 1932505 yebZ 4491925 yebZ Escherichia coli APEC O1 hypothetical protein YP_852908.1 1931633 R 405955 CDS YP_852909.1 117623996 4491926 1933585..1934010 1 NC_008563.1 hypothetical protein 1934010 yobB 4491926 yobB Escherichia coli APEC O1 hypothetical protein YP_852909.1 1933585 D 405955 CDS YP_852910.1 117623997 4491927 1934033..1934695 1 NC_008563.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1934695 exoX 4491927 exoX Escherichia coli APEC O1 exodeoxyribonuclease X YP_852910.1 1934033 D 405955 CDS YP_852911.1 117623998 4491928 complement(1934692..1936752) 1 NC_008563.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1936752 ptrB 4491928 ptrB Escherichia coli APEC O1 protease 2 YP_852911.1 1934692 R 405955 CDS YP_852912.1 117623999 4491929 complement(1936961..1937620) 1 NC_008563.1 hypothetical protein 1937620 yebE 4491929 yebE Escherichia coli APEC O1 hypothetical protein YP_852912.1 1936961 R 405955 CDS YP_852913.1 117624000 4491930 complement(1937947..1938315) 1 NC_008563.1 secreted protein; unknown function; hypothetical protein 1938315 yebF 4491930 yebF Escherichia coli APEC O1 hypothetical protein YP_852913.1 1937947 R 405955 CDS YP_852914.1 117624001 4491931 1938794..1939972 1 NC_008563.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1939972 purT 4491931 purT Escherichia coli APEC O1 phosphoribosylglycinamide formyltransferase 2 YP_852914.1 1938794 D 405955 CDS YP_852915.1 117624002 4491932 complement(1940028..1940669) 1 NC_008563.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1940669 eda 4491932 eda Escherichia coli APEC O1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_852915.1 1940028 R 405955 CDS YP_852916.1 117624003 4491933 complement(1940706..1942583) 1 NC_008563.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1942583 edd 4491933 edd Escherichia coli APEC O1 phosphogluconate dehydratase YP_852916.1 1940706 R 405955 CDS YP_852917.1 117624004 4491934 complement(1942752..1944227) 1 NC_008563.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1944227 zwf 4491934 zwf Escherichia coli APEC O1 glucose-6-phosphate 1-dehydrogenase YP_852917.1 1942752 R 405955 CDS YP_852918.1 117624005 4491935 1944565..1945434 1 NC_008563.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1945434 yebK 4491935 yebK Escherichia coli APEC O1 DNA-binding transcriptional regulator HexR YP_852918.1 1944565 D 405955 CDS YP_852919.1 117624006 4491936 1945421..1947004 1 NC_008563.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1947004 pykA 4491936 pykA Escherichia coli APEC O1 pyruvate kinase YP_852919.1 1945421 D 405955 CDS YP_852920.1 117624007 4491937 complement(1947136..1948107) 1 NC_008563.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1948107 msbB 4491937 msbB Escherichia coli APEC O1 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_852920.1 1947136 R 405955 CDS YP_852921.1 117624008 4491938 complement(1948226..1949548) 1 NC_008563.1 hypothetical protein 1949548 4491938 APECO1_906 Escherichia coli APEC O1 hypothetical protein YP_852921.1 1948226 R 405955 CDS YP_852922.1 117624009 4491939 complement(1949564..1950550) 1 NC_008563.1 yebL precursor; involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1950550 znuA 4491939 znuA Escherichia coli APEC O1 high-affinity zinc transporter periplasmic protein YP_852922.1 1949564 R 405955 CDS YP_852923.1 117624010 4491478 1950575..1951330 1 NC_008563.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1951330 znuC 4491478 znuC Escherichia coli APEC O1 high-affinity zinc transporter ATPase YP_852923.1 1950575 D 405955 CDS YP_852924.1 117624011 4491479 1951327..1952112 1 NC_008563.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1952112 znuB 4491479 znuB Escherichia coli APEC O1 high-affinity zinc transporter membrane protein YP_852924.1 1951327 D 405955 CDS YP_852925.1 117624012 4491480 complement(1952329..1953339) 1 NC_008563.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1953339 ruvB 4491480 ruvB Escherichia coli APEC O1 Holliday junction DNA helicase RuvB YP_852925.1 1952329 R 405955 CDS YP_852926.1 117624013 4491481 complement(1953348..1953959) 1 NC_008563.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1953959 ruvA 4491481 ruvA Escherichia coli APEC O1 Holliday junction DNA helicase RuvA YP_852926.1 1953348 R 405955 CDS YP_852927.1 117624014 4491482 1954236..1954838 1 NC_008563.1 hypothetical protein 1954838 yebB 4491482 yebB Escherichia coli APEC O1 hypothetical protein YP_852927.1 1954236 D 405955 CDS YP_852928.1 117624015 4491483 complement(1954840..1955364) 1 NC_008563.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1955364 ruvC 4491483 ruvC Escherichia coli APEC O1 Holliday junction resolvase YP_852928.1 1954840 R 405955 CDS YP_852929.1 117624016 4491484 complement(1955396..1956136) 1 NC_008563.1 hypothetical protein 1956136 yebC 4491484 yebC Escherichia coli APEC O1 hypothetical protein YP_852929.1 1955396 R 405955 CDS YP_852930.1 117624017 4491485 complement(1956165..1956608) 1 NC_008563.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1956608 ntpA 4491485 ntpA Escherichia coli APEC O1 dATP pyrophosphohydrolase YP_852930.1 1956165 R 405955 CDS YP_852931.1 117624018 4491486 complement(1956610..1958382) 1 NC_008563.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1958382 aspS 4491486 aspS Escherichia coli APEC O1 aspartyl-tRNA synthetase YP_852931.1 1956610 R 405955 CDS YP_852932.1 117624019 4491487 1958692..1959258 1 NC_008563.1 hypothetical protein 1959258 yecD 4491487 yecD Escherichia coli APEC O1 hypothetical protein YP_852932.1 1958692 D 405955 CDS YP_852933.1 117624020 4491488 1959255..1960073 1 NC_008563.1 hypothetical protein 1960073 yecE 4491488 yecE Escherichia coli APEC O1 hypothetical protein YP_852933.1 1959255 D 405955 CDS YP_852934.1 117624021 4491489 1960096..1960521 1 NC_008563.1 hypothetical protein 1960521 yecN 4491489 yecN Escherichia coli APEC O1 hypothetical protein YP_852934.1 1960096 D 405955 CDS YP_852935.1 117624022 4491490 1960562..1961305 1 NC_008563.1 hypothetical protein 1961305 yecO 4491490 yecO Escherichia coli APEC O1 hypothetical protein YP_852935.1 1960562 D 405955 CDS YP_852936.1 117624023 4491491 1961302..1962273 1 NC_008563.1 hypothetical protein 1962273 yecP 4491491 yecP Escherichia coli APEC O1 hypothetical protein YP_852936.1 1961302 D 405955 CDS YP_852937.1 117624024 4491495 complement(1962438..1964780) 1 NC_008563.1 trimethylamine-N-oxide reductase 2 1964780 bisZ 4491495 bisZ Escherichia coli APEC O1 trimethylamine-N-oxide reductase 2 YP_852937.1 1962438 R 405955 CDS YP_852938.1 117624025 4491496 complement(1964891..1965991) 1 NC_008563.1 TMAO reductase III (TorYZ), cytochrome c-type subunit 1965991 torY 4491496 torY Escherichia coli APEC O1 TMAO reductase III (TorYZ), cytochrome c-type subunit YP_852938.1 1964891 R 405955 CDS YP_852939.1 117624026 4491497 complement(1966379..1967125) 1 NC_008563.1 copper homeostasis protein CutC 1967125 cutC 4491497 cutC Escherichia coli APEC O1 copper homeostasis protein CutC YP_852939.1 1966379 R 405955 CDS YP_852940.1 117624027 4495750 complement(1967139..1967711) 1 NC_008563.1 hypothetical protein 1967711 yecM 4495750 yecM Escherichia coli APEC O1 hypothetical protein YP_852940.1 1967139 R 405955 CDS YP_852941.1 117624028 4495751 1967921..1969654 1 NC_008563.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1969654 argS 4495751 argS Escherichia coli APEC O1 arginyl-tRNA synthetase YP_852941.1 1967921 D 405955 CDS YP_852942.1 117624029 4495752 complement(1969707..1970099) 1 NC_008563.1 flagellar protein FlhE 1970099 flhE 4495752 flhE Escherichia coli APEC O1 flagellar protein FlhE YP_852942.1 1969707 R 405955 CDS YP_852943.2 162317574 4495753 complement(1970099..1972177) 1 NC_008563.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1972177 flhA 4495753 flhA Escherichia coli APEC O1 flagellar biosynthesis protein FlhA YP_852943.2 1970099 R 405955 CDS YP_852944.1 117624031 4495754 complement(1972170..1973318) 1 NC_008563.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1973318 flhB 4495754 flhB Escherichia coli APEC O1 flagellar biosynthesis protein FlhB YP_852944.1 1972170 R 405955 CDS YP_852945.1 117624032 4495755 complement(1973527..1974171) 1 NC_008563.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1974171 cheZ 4495755 cheZ Escherichia coli APEC O1 chemotaxis regulator CheZ YP_852945.1 1973527 R 405955 CDS YP_852946.1 117624033 4495756 complement(1974182..1974571) 1 NC_008563.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1974571 cheY 4495756 cheY Escherichia coli APEC O1 chemotaxis regulatory protein CheY YP_852946.1 1974182 R 405955 CDS YP_852947.1 117624034 4495757 complement(1974586..1975635) 1 NC_008563.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1975635 cheB 4495757 cheB Escherichia coli APEC O1 chemotaxis-specific methylesterase YP_852947.1 1974586 R 405955 CDS YP_852948.1 117624035 4495758 complement(1975638..1976498) 1 NC_008563.1 methylates the MCP; chemotaxis methyltransferase CheR 1976498 cheR 4495758 cheR Escherichia coli APEC O1 chemotaxis methyltransferase CheR YP_852948.1 1975638 R 405955 CDS YP_852949.1 117624036 4495759 complement(1976789..1978450) 1 NC_008563.1 methyl-accepting chemotaxis protein II 1978450 tar 4495759 tar Escherichia coli APEC O1 methyl-accepting chemotaxis protein II YP_852949.1 1976789 R 405955 CDS YP_852950.1 117624037 4495760 complement(1978595..1979098) 1 NC_008563.1 purine-binding chemotaxis protein 1979098 cheW 4495760 cheW Escherichia coli APEC O1 purine-binding chemotaxis protein YP_852950.1 1978595 R 405955 CDS YP_852951.1 117624038 4495761 complement(1979119..1981122) 1 NC_008563.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1981122 cheA 4495761 cheA Escherichia coli APEC O1 chemotaxis protein CheA YP_852951.1 1979119 R 405955 CDS YP_852952.1 117624039 4495762 complement(1981088..1982014) 1 NC_008563.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1982014 motB 4495762 motB Escherichia coli APEC O1 flagellar motor protein MotB YP_852952.1 1981088 R 405955 CDS YP_852953.1 117624040 4495763 complement(1982011..1982898) 1 NC_008563.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1982898 motA 4495763 motA Escherichia coli APEC O1 flagellar motor protein MotA YP_852953.1 1982011 R 405955 CDS YP_852954.1 117624041 4495764 complement(1983025..1983603) 1 NC_008563.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1983603 flhC 4495764 flhC Escherichia coli APEC O1 transcriptional activator FlhC YP_852954.1 1983025 R 405955 CDS YP_852955.1 117624042 4495765 complement(1983606..1983965) 1 NC_008563.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1983965 flhD 4495765 flhD Escherichia coli APEC O1 transcriptional activator FlhD YP_852955.1 1983606 R 405955 CDS YP_852956.1 117624043 4495766 1984736..1985164 1 NC_008563.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1985164 yecG 4495766 yecG Escherichia coli APEC O1 universal stress protein UspC YP_852956.1 1984736 D 405955 CDS YP_852957.1 117624044 4495767 complement(1985171..1986604) 1 NC_008563.1 trehalose-6-phosphate synthase 1986604 otsA 4495767 otsA Escherichia coli APEC O1 trehalose-6-phosphate synthase YP_852957.1 1985171 R 405955 CDS YP_852958.1 117624045 4495768 complement(1986570..1987427) 1 NC_008563.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1987427 otsB 4495768 otsB Escherichia coli APEC O1 trehalose-6-phosphate phosphatase YP_852958.1 1986570 R 405955 CDS YP_852959.1 117624046 4494623 complement(1987537..1988526) 1 NC_008563.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1988526 araH 4494623 araH Escherichia coli APEC O1 L-arabinose transporter permease YP_852959.1 1987537 R 405955 CDS YP_852960.1 117624047 4494624 complement(1988538..1990097) 1 NC_008563.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1990097 araG 4494624 araG Escherichia coli APEC O1 L-arabinose transporter ATP-binding protein YP_852960.1 1988538 R 405955 CDS YP_852961.1 117624048 4494625 complement(1990122..1991162) 1 NC_008563.1 L-arabinose-binding periplasmic protein 1991162 araF 4494625 araF Escherichia coli APEC O1 L-arabinose-binding periplasmic protein YP_852961.1 1990122 R 405955 CDS YP_852962.1 117624049 4494626 1991908..1992411 1 NC_008563.1 ferritin-like protein 1992411 yecI 4494626 yecI Escherichia coli APEC O1 ferritin-like protein YP_852962.1 1991908 D 405955 CDS YP_852964.1 117624051 4494628 1993205..1993528 1 NC_008563.1 hypothetical protein 1993528 yecR 4494628 yecR Escherichia coli APEC O1 hypothetical protein YP_852964.1 1993205 D 405955 CDS YP_852965.1 117624052 4494629 1993700..1994197 1 NC_008563.1 cytoplasmic iron storage protein; ferritin 1994197 ftn 4494629 ftn Escherichia coli APEC O1 ferritin YP_852965.1 1993700 D 405955 CDS YP_852966.1 117624053 4494630 1994665..1995876 1 NC_008563.1 tyrosine-specific transporter 1995876 tyrP 4494630 tyrP Escherichia coli APEC O1 tyrosine-specific transporter YP_852966.1 1994665 D 405955 CDS YP_852967.1 117624054 4494631 complement(1995927..1996592) 1 NC_008563.1 hypothetical protein 1996592 4494631 APECO1_953 Escherichia coli APEC O1 hypothetical protein YP_852967.1 1995927 R 405955 CDS YP_852968.1 117624055 4494632 complement(1997242..1997790) 1 NC_008563.1 CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyl transferase; phosphatidylglycerophosphate synthetase 1997790 pgsA 4494632 pgsA Escherichia coli APEC O1 phosphatidylglycerophosphate synthetase YP_852968.1 1997242 R 405955 CDS YP_852969.1 117624056 4494633 complement(1997847..1999679) 1 NC_008563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1999679 uvrC 4494633 uvrC Escherichia coli APEC O1 excinuclease ABC subunit C YP_852969.1 1997847 R 405955 CDS YP_852970.1 117624057 4494634 complement(1999676..2000296) 1 NC_008563.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2000296 uvrY 4494634 uvrY Escherichia coli APEC O1 response regulator YP_852970.1 1999676 R 405955 CDS YP_852971.1 117624058 4494635 complement(2001083..2001805) 1 NC_008563.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2001805 sdiA 4494635 sdiA Escherichia coli APEC O1 DNA-binding transcriptional activator SdiA YP_852971.1 2001083 R 405955 CDS YP_852972.1 117624059 4494636 complement(2002035..2002787) 1 NC_008563.1 amino acid ABC transporter ATP-binding protein 2002787 yecC 4494636 yecC Escherichia coli APEC O1 amino acid ABC transporter ATP-binding protein YP_852972.1 2002035 R 405955 CDS YP_852973.1 117624060 4494637 complement(2002784..2003452) 1 NC_008563.1 transport system permease 2003452 yecS 4494637 yecS Escherichia coli APEC O1 transport system permease YP_852973.1 2002784 R 405955 CDS YP_852974.1 117624061 4494638 complement(2003467..2004549) 1 NC_008563.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2004549 yedO 4494638 yedO Escherichia coli APEC O1 D-cysteine desulfhydrase YP_852974.1 2003467 R 405955 CDS YP_852975.1 117624062 4494639 complement(2004558..2005415) 1 NC_008563.1 cystine transporter subunit 2005415 fliY 4494639 fliY Escherichia coli APEC O1 cystine transporter subunit YP_852975.1 2004558 R 405955 CDS YP_852976.1 117624063 4494640 complement(2005446..2006033) 1 NC_008563.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2006033 fliZ 4494640 fliZ Escherichia coli APEC O1 flagella biosynthesis protein FliZ YP_852976.1 2005446 R 405955 CDS YP_852977.1 117624064 4494641 complement(2006043..2006762) 1 NC_008563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2006762 fliA 4494641 fliA Escherichia coli APEC O1 flagellar biosynthesis sigma factor YP_852977.1 2006043 R 405955 CDS YP_852978.1 117624065 4494642 complement(2007082..2008839) 1 NC_008563.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2008839 fliC 4494642 fliC Escherichia coli APEC O1 flagellin YP_852978.1 2007082 R 405955 CDS YP_852979.1 117624066 4491850 2009105..2010511 1 NC_008563.1 involved in flagellin assembly; flagellar capping protein 2010511 fliD 4491850 fliD Escherichia coli APEC O1 flagellar capping protein YP_852979.1 2009105 D 405955 CDS YP_852980.1 117624067 4491851 2010536..2010946 1 NC_008563.1 flagellin specific chaperone; flagellar protein FliS 2010946 fliS 4491851 fliS Escherichia coli APEC O1 flagellar protein FliS YP_852980.1 2010536 D 405955 CDS YP_852981.1 117624068 4491852 2010946..2011311 1 NC_008563.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2011311 fliT 4491852 fliT Escherichia coli APEC O1 flagellar biosynthesis protein FliT YP_852981.1 2010946 D 405955 CDS YP_852982.1 117624069 4491853 2011389..2012876 1 NC_008563.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2012876 amyA 4491853 amyA Escherichia coli APEC O1 alpha-amylase YP_852982.1 2011389 D 405955 CDS YP_852983.1 117624070 4491854 complement(2012910..2013326) 1 NC_008563.1 hypothetical protein 2013326 yedD 4491854 yedD Escherichia coli APEC O1 hypothetical protein YP_852983.1 2012910 R 405955 CDS YP_852984.1 117624071 4491855 2013510..2014715 1 NC_008563.1 hypothetical protein 2014715 yedE 4491855 yedE Escherichia coli APEC O1 hypothetical protein YP_852984.1 2013510 D 405955 CDS YP_852985.1 117624072 4491856 2014961..2015722 1 NC_008563.1 hypothetical protein 2015722 yedK 4491856 yedK Escherichia coli APEC O1 hypothetical protein YP_852985.1 2014961 D 405955 CDS YP_852986.1 117624073 4491857 2016235..2017317 1 NC_008563.1 outer membrane porin protein NmpC 2017317 nmpC 4491857 nmpC Escherichia coli APEC O1 outer membrane porin protein NmpC YP_852986.1 2016235 D 405955 CDS YP_852987.1 117624074 4491858 complement(2017819..2018616) 1 NC_008563.1 transcriptional regulator 2018616 ybcM 4491858 ybcM Escherichia coli APEC O1 transcriptional regulator YP_852987.1 2017819 R 405955 CDS YP_852988.1 117624075 4491859 complement(2018626..2019177) 1 NC_008563.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor 2019177 ybcL 4491859 ybcL Escherichia coli APEC O1 kinase inhibitor YP_852988.1 2018626 R 405955 CDS YP_852989.1 117624076 4491860 complement(2019346..2019843) 1 NC_008563.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 2019843 emrE 4491860 emrE Escherichia coli APEC O1 multidrug efflux protein YP_852989.1 2019346 R 405955 CDS YP_852990.1 117624077 4491861 complement(2020023..2020337) 1 NC_008563.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2020337 fliE 4491861 fliE Escherichia coli APEC O1 flagellar hook-basal body protein FliE YP_852990.1 2020023 R 405955 CDS YP_852991.1 117624078 4491862 2020552..2021553 1 NC_008563.1 flagellar M-ring protein 2021553 fliF 4491862 fliF Escherichia coli APEC O1 flagellar M-ring protein YP_852991.1 2020552 D 405955 CDS YP_852992.1 117624079 4491863 2022204..2023199 1 NC_008563.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2023199 fliG 4491863 fliG Escherichia coli APEC O1 flagellar motor switch protein G YP_852992.1 2022204 D 405955 CDS YP_852993.1 117624080 4491864 2023192..2023878 1 NC_008563.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2023878 fliH 4491864 fliH Escherichia coli APEC O1 flagellar assembly protein H YP_852993.1 2023192 D 405955 CDS YP_852994.1 117624081 4491865 2023878..2025251 1 NC_008563.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2025251 fliI 4491865 fliI Escherichia coli APEC O1 flagellum-specific ATP synthase YP_852994.1 2023878 D 405955 CDS YP_852995.1 117624082 4491866 2025270..2025713 1 NC_008563.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2025713 fliJ 4491866 fliJ Escherichia coli APEC O1 flagellar biosynthesis chaperone YP_852995.1 2025270 D 405955 CDS YP_852996.1 117624083 4491867 2025710..2026837 1 NC_008563.1 flagellar hook-length control protein 2026837 fliK 4491867 fliK Escherichia coli APEC O1 flagellar hook-length control protein YP_852996.1 2025710 D 405955 CDS YP_852997.1 117624084 4491868 2026942..2027406 1 NC_008563.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2027406 fliL 4491868 fliL Escherichia coli APEC O1 flagellar basal body-associated protein FliL YP_852997.1 2026942 D 405955 CDS YP_852998.1 117624085 4492055 2027366..2028415 1 NC_008563.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2028415 fliM 4492055 fliM Escherichia coli APEC O1 flagellar motor switch protein FliM YP_852998.1 2027366 D 405955 CDS YP_852999.1 117624086 4492056 2028412..2028825 1 NC_008563.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2028825 fliN 4492056 fliN Escherichia coli APEC O1 flagellar motor switch protein FliN YP_852999.1 2028412 D 405955 CDS YP_853000.1 117624087 4492057 2028825..2029193 1 NC_008563.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2029193 fliO 4492057 fliO Escherichia coli APEC O1 flagellar biosynthesis protein FliO YP_853000.1 2028825 D 405955 CDS YP_853001.1 117624088 4492058 2029193..2029930 1 NC_008563.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2029930 fliP 4492058 fliP Escherichia coli APEC O1 flagellar biosynthesis protein FliP YP_853001.1 2029193 D 405955 CDS YP_853002.1 117624089 4492059 2029940..2030209 1 NC_008563.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2030209 fliQ 4492059 fliQ Escherichia coli APEC O1 flagellar biosynthesis protein FliQ YP_853002.1 2029940 D 405955 CDS YP_853003.1 117624090 4492060 2030218..2031003 1 NC_008563.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2031003 fliR 4492060 fliR Escherichia coli APEC O1 flagellar biosynthesis protein FliR YP_853003.1 2030218 D 405955 CDS YP_853004.1 117624091 4492061 2031293..2031916 1 NC_008563.1 positive regulator for ctr capsule biosynthesis, positive transcription factor 2031916 rcsA 4492061 rcsA Escherichia coli APEC O1 positive regulator for ctr capsule biosynthesis, positive transcription factor YP_853004.1 2031293 D 405955 CDS YP_853005.1 117624092 4492062 2031993..2032268 1 NC_008563.1 hypothetical protein 2032268 4492062 APECO1_991 Escherichia coli APEC O1 hypothetical protein YP_853005.1 2031993 D 405955 CDS YP_853007.1 117624094 4492064 2032836..2033651 1 NC_008563.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2033651 yedP 4492064 yedP Escherichia coli APEC O1 mannosyl-3-phosphoglycerate phosphatase YP_853007.1 2032836 D 405955 CDS YP_853008.1 117624095 4492065 complement(2033648..2035342) 1 NC_008563.1 hypothetical protein 2035342 yedQ 4492065 yedQ Escherichia coli APEC O1 hypothetical protein YP_853008.1 2033648 R 405955 CDS YP_853009.1 117624096 4492639 complement(2035774..2036691) 1 NC_008563.1 hypothetical protein 2036691 yedI 4492639 yedI Escherichia coli APEC O1 hypothetical protein YP_853009.1 2035774 R 405955 CDS YP_853010.1 117624097 4492640 2036864..2037784 1 NC_008563.1 hypothetical protein 2037784 yedA 4492640 yedA Escherichia coli APEC O1 hypothetical protein YP_853010.1 2036864 D 405955 CDS YP_853011.1 117624098 4492641 complement(2037773..2038243) 1 NC_008563.1 DNA mismatch endonuclease, patch repair protein 2038243 vsr 4492641 vsr Escherichia coli APEC O1 DNA mismatch endonuclease, patch repair protein YP_853011.1 2037773 R 405955 CDS YP_853012.1 117624099 4492642 complement(2038224..2039642) 1 NC_008563.1 DNA cytosine methylase 2039642 dcm 4492642 dcm Escherichia coli APEC O1 DNA cytosine methylase YP_853012.1 2038224 R 405955 CDS YP_853013.1 117624100 4492643 complement(2039709..2040404) 1 NC_008563.1 hypothetical protein 2040404 yedJ 4492643 yedJ Escherichia coli APEC O1 hypothetical protein YP_853013.1 2039709 R 405955 CDS YP_853014.1 117624101 4492644 complement(2040444..2040809) 1 NC_008563.1 Outer membrane protein N precursor 2040809 yedR 4492644 yedR Escherichia coli APEC O1 Outer membrane protein N precursor YP_853014.1 2040444 R 405955 CDS YP_853015.1 117624102 4492645 2041345..2042490 1 NC_008563.1 Outer membrane protein N precursor 2042490 ompN 4492645 ompN Escherichia coli APEC O1 Outer membrane protein N precursor YP_853015.1 2041345 D 405955 CDS YP_853016.1 117624103 4492646 2043085..2043936 1 NC_008563.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2043936 hchA 4492646 hchA Escherichia coli APEC O1 chaperone protein HchA YP_853016.1 2043085 D 405955 CDS YP_853017.1 117624104 4492647 complement(2044043..2045401) 1 NC_008563.1 2-component sensor protein 2045401 yedV 4492647 yedV Escherichia coli APEC O1 2-component sensor protein YP_853017.1 2044043 R 405955 CDS YP_853018.1 117624105 4492648 complement(2045401..2046183) 1 NC_008563.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2046183 yedW 4492648 yedW Escherichia coli APEC O1 transcriptional regulatory protein YedW YP_853018.1 2045401 R 405955 CDS YP_853019.1 117624106 4492649 2046205..2046618 1 NC_008563.1 hypothetical protein 2046618 yedX 4492649 yedX Escherichia coli APEC O1 hypothetical protein YP_853019.1 2046205 D 405955 CDS YP_853020.1 117624107 4492650 2046727..2047731 1 NC_008563.1 reductase; in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2047731 yedY 4492650 yedY Escherichia coli APEC O1 sulfite oxidase subunit YedY YP_853020.1 2046727 D 405955 CDS YP_853021.1 117624108 4492651 2047732..2048367 1 NC_008563.1 conserved inner membrane protein; in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2048367 yedZ 4492651 yedZ Escherichia coli APEC O1 sulfite oxidase subunit YedZ YP_853021.1 2047732 D 405955 CDS YP_853022.1 117624109 4492652 2048927..2049274 1 NC_008563.1 conserved metal-binding protein; YodA protein 2049274 yodA 4492652 yodA Escherichia coli APEC O1 YodA protein YP_853022.1 2048927 D 405955 CDS YP_853023.1 117624110 4492653 2049310..2049639 1 NC_008563.1 hypothetical protein 2049639 4492653 APECO1_1009 Escherichia coli APEC O1 hypothetical protein YP_853023.1 2049310 D 405955 CDS YP_853024.1 117624111 4492654 2050863..2051642 1 NC_008563.1 hypothetical protein 2051642 4492654 APECO1_1010 Escherichia coli APEC O1 hypothetical protein YP_853024.1 2050863 D 405955 CDS YP_853025.1 117624112 4492655 2051722..2052057 1 NC_008563.1 hypothetical protein 2052057 4492655 APECO1_1011 Escherichia coli APEC O1 hypothetical protein YP_853025.1 2051722 D 405955 CDS YP_853026.1 117624113 4492656 complement(2052150..2052428) 1 NC_008563.1 hypothetical protein 2052428 4492656 APECO1_1012 Escherichia coli APEC O1 hypothetical protein YP_853026.1 2052150 R 405955 CDS YP_853027.1 117624114 4492657 complement(2052425..2054491) 1 NC_008563.1 hypothetical protein 2054491 4492657 APECO1_6001 Escherichia coli APEC O1 hypothetical protein YP_853027.1 2052425 R 405955 CDS YP_853028.1 117624115 4493946 complement(2054544..2058026) 1 NC_008563.1 tail component of prophage 2058026 4493946 APECO1_6002 Escherichia coli APEC O1 tail component of prophage YP_853028.1 2054544 R 405955 CDS YP_853029.1 117624116 4493947 complement(2058087..2058758) 1 NC_008563.1 tail assembly protein I 2058758 4493947 APECO1_6003 Escherichia coli APEC O1 tail assembly protein I YP_853029.1 2058087 R 405955 CDS YP_853030.1 117624117 4493948 complement(2058656..2059399) 1 NC_008563.1 tail assembly protein 2059399 4493948 APECO1_6004 Escherichia coli APEC O1 tail assembly protein YP_853030.1 2058656 R 405955 CDS YP_853031.1 117624118 4493949 2059398..2060108 1 NC_008563.1 hypothetical protein 2060108 4493949 APECO1_6005 Escherichia coli APEC O1 hypothetical protein YP_853031.1 2059398 D 405955 CDS YP_853032.1 117624119 4493950 complement(2060102..2060443) 1 NC_008563.1 phage-related; minor tail protein 2060443 4493950 APECO1_6006 Escherichia coli APEC O1 minor tail protein YP_853032.1 2060102 R 405955 CDS YP_853033.1 117624120 4493951 complement(2060436..2063681) 1 NC_008563.1 phage-related minor tail protein 2063681 4493951 APECO1_6007 Escherichia coli APEC O1 phage-related minor tail protein YP_853033.1 2060436 R 405955 CDS YP_853034.1 117624121 4493952 complement(2063722..2064012) 1 NC_008563.1 Gp14; phage-related minor tail protein 2064012 4493952 APECO1_1015 Escherichia coli APEC O1 phage-related minor tail protein YP_853034.1 2063722 R 405955 CDS YP_853035.1 117624122 4493953 complement(2064024..2064410) 1 NC_008563.1 tail assembly chaperone 2064410 4493953 APECO1_1016 Escherichia coli APEC O1 tail assembly chaperone YP_853035.1 2064024 R 405955 CDS YP_853036.1 117624123 4493954 complement(2064410..2065165) 1 NC_008563.1 phage major tail subunit 2065165 gp14 4493954 gp14 Escherichia coli APEC O1 phage major tail subunit YP_853036.1 2064410 R 405955 CDS YP_853037.1 117624124 4493955 complement(2065174..2065518) 1 NC_008563.1 Gp11; hypothetical protein 2065518 4493955 APECO1_1018 Escherichia coli APEC O1 hypothetical protein YP_853037.1 2065174 R 405955 CDS YP_853038.1 117624125 4493956 complement(2065515..2065964) 1 NC_008563.1 Gp10; hypothetical protein 2065964 4493956 APECO1_1019 Escherichia coli APEC O1 hypothetical protein YP_853038.1 2065515 R 405955 CDS YP_853039.1 117624126 4493957 complement(2065961..2066299) 1 NC_008563.1 head-tail adaptor 2066299 gp7 4493957 gp7 Escherichia coli APEC O1 head-tail adaptor YP_853039.1 2065961 R 405955 CDS YP_853040.1 117624127 4493958 complement(2066308..2066796) 1 NC_008563.1 hypothetical protein 2066796 4493958 APECO1_1021 Escherichia coli APEC O1 hypothetical protein YP_853040.1 2066308 R 405955 CDS YP_853041.1 117624128 4493959 complement(2066702..2067919) 1 NC_008563.1 phage capsid protein 2067919 4493959 APECO1_1022 Escherichia coli APEC O1 phage capsid protein YP_853041.1 2066702 R 405955 CDS YP_853042.1 117624129 4493960 complement(2067934..2068533) 1 NC_008563.1 phage capsid protease 2068533 4493960 APECO1_1023 Escherichia coli APEC O1 phage capsid protease YP_853042.1 2067934 R 405955 CDS YP_853043.1 117624130 4493961 complement(2068526..2069752) 1 NC_008563.1 phage portal protein 2069752 4493961 APECO1_1024 Escherichia coli APEC O1 phage portal protein YP_853043.1 2068526 R 405955 CDS YP_853044.1 117624131 4493962 complement(2069900..2071657) 1 NC_008563.1 phage terminase 2071657 4493962 APECO1_1025 Escherichia coli APEC O1 phage terminase YP_853044.1 2069900 R 405955 CDS YP_853045.1 117624132 4493963 complement(2071657..2072139) 1 NC_008563.1 phage terminase 2072139 4493963 APECO1_1026 Escherichia coli APEC O1 phage terminase YP_853045.1 2071657 R 405955 CDS YP_853046.1 117624133 4493964 complement(2072287..2072637) 1 NC_008563.1 restriction endonuclase; HnhC 2072637 hnhC 4493964 hnhC Escherichia coli APEC O1 HnhC YP_853046.1 2072287 R 405955 CDS YP_853047.1 117624134 4493965 complement(2072680..2073147) 1 NC_008563.1 endopeptidase 2073147 4493965 APECO1_1028 Escherichia coli APEC O1 endopeptidase YP_853047.1 2072680 R 405955 CDS YP_853048.1 117624135 4493264 complement(2073144..2073677) 1 NC_008563.1 phage lysozyme 2073677 4493264 APECO1_1029 Escherichia coli APEC O1 phage lysozyme YP_853048.1 2073144 R 405955 CDS YP_853049.1 117624136 4493265 complement(2073741..2074091) 1 NC_008563.1 hypothetical protein 2074091 ydfR 4493265 ydfR Escherichia coli APEC O1 hypothetical protein YP_853049.1 2073741 R 405955 CDS YP_853050.1 117624137 4493266 complement(2075039..2075752) 1 NC_008563.1 hypothetical protein 2075752 4493266 APECO1_1031 Escherichia coli APEC O1 hypothetical protein YP_853050.1 2075039 R 405955 CDS YP_853051.1 117624138 4493267 complement(2075982..2076677) 1 NC_008563.1 Q antiterminator encoded by prophage CP-933P 2076677 4493267 APECO1_1032 Escherichia coli APEC O1 Q antiterminator encoded by prophage CP-933P YP_853051.1 2075982 R 405955 CDS YP_853052.1 117624139 4493268 complement(2076668..2077033) 1 NC_008563.1 Holliday junction resolvase 2077033 4493268 APECO1_1033 Escherichia coli APEC O1 Holliday junction resolvase YP_853052.1 2076668 R 405955 CDS YP_853053.1 117624140 4493269 complement(2077034..2078089) 1 NC_008563.1 hypothetical protein 2078089 4493269 APECO1_1034 Escherichia coli APEC O1 hypothetical protein YP_853053.1 2077034 R 405955 CDS YP_853054.1 117624141 4493270 complement(2079275..2079790) 1 NC_008563.1 hypothetical protein 2079790 4493270 APECO1_1035 Escherichia coli APEC O1 hypothetical protein YP_853054.1 2079275 R 405955 CDS YP_853055.1 117624142 4493271 complement(2080232..2080621) 1 NC_008563.1 hypothetical protein 2080621 4493271 APECO1_1036 Escherichia coli APEC O1 hypothetical protein YP_853055.1 2080232 R 405955 CDS YP_853056.1 117624143 4493272 complement(2080590..2080901) 1 NC_008563.1 hypothetical protein 2080901 4493272 APECO1_1037 Escherichia coli APEC O1 hypothetical protein YP_853056.1 2080590 R 405955 CDS YP_853057.1 117624144 4493273 complement(2080917..2081324) 1 NC_008563.1 hypothetical protein 2081324 4493273 APECO1_1038 Escherichia coli APEC O1 hypothetical protein YP_853057.1 2080917 R 405955 CDS YP_853058.1 117624145 4493274 complement(2081365..2082441) 1 NC_008563.1 hypothetical protein 2082441 4493274 APECO1_1040 Escherichia coli APEC O1 hypothetical protein YP_853058.1 2081365 R 405955 CDS YP_853059.1 117624146 4493275 complement(2082507..2082932) 1 NC_008563.1 hypothetical protein 2082932 4493275 APECO1_1041 Escherichia coli APEC O1 hypothetical protein YP_853059.1 2082507 R 405955 CDS YP_853060.1 117624147 4493276 complement(2082929..2083255) 1 NC_008563.1 regulatory protein 2083255 4493276 APECO1_1042 Escherichia coli APEC O1 regulatory protein YP_853060.1 2082929 R 405955 CDS YP_853061.1 117624148 4493277 2083263..2083682 1 NC_008563.1 transcriptional regulator 2083682 4493277 APECO1_1043 Escherichia coli APEC O1 transcriptional regulator YP_853061.1 2083263 D 405955 CDS YP_853062.1 117624149 4493278 2083983..2084339 1 NC_008563.1 hypothetical protein 2084339 4493278 APECO1_1044 Escherichia coli APEC O1 hypothetical protein YP_853062.1 2083983 D 405955 CDS YP_853063.1 117624150 4493279 complement(2084633..2084926) 1 NC_008563.1 hypothetical protein 2084926 4493279 APECO1_1045 Escherichia coli APEC O1 hypothetical protein YP_853063.1 2084633 R 405955 CDS YP_853064.1 117624151 4493280 complement(2085001..2085333) 1 NC_008563.1 hypothetical protein 2085333 4493280 APECO1_1046 Escherichia coli APEC O1 hypothetical protein YP_853064.1 2085001 R 405955 CDS YP_853065.1 117624152 4493281 2085328..2085585 1 NC_008563.1 hypothetical protein 2085585 4493281 APECO1_1047 Escherichia coli APEC O1 hypothetical protein YP_853065.1 2085328 D 405955 CDS YP_853066.1 117624153 4493282 2085665..2088136 1 NC_008563.1 hypothetical protein 2088136 4493282 APECO1_1048 Escherichia coli APEC O1 hypothetical protein YP_853066.1 2085665 D 405955 CDS YP_853067.1 117624154 4492528 2088398..2089423 1 NC_008563.1 phage integrase 2089423 4492528 APECO1_1049 Escherichia coli APEC O1 phage integrase YP_853067.1 2088398 D 405955 CDS YP_853068.1 117624155 4492529 2089620..2090456 1 NC_008563.1 hypothetical protein 2090456 4492529 APECO1_1050 Escherichia coli APEC O1 hypothetical protein YP_853068.1 2089620 D 405955 CDS YP_853069.1 117624156 4492530 2091013..2091975 1 NC_008563.1 phage integrase 2091975 4492530 APECO1_1051 Escherichia coli APEC O1 phage integrase YP_853069.1 2091013 D 405955 CDS YP_853070.1 117624157 4492531 complement(2092250..2093554) 1 NC_008563.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 2093554 4492531 APECO1_1052 Escherichia coli APEC O1 salicylate synthase Irp9 YP_853070.1 2092250 R 405955 CDS YP_853071.1 117624158 4492532 complement(2093582..2094970) 1 NC_008563.1 hypothetical protein 2094970 ybtX 4492532 ybtX Escherichia coli APEC O1 hypothetical protein YP_853071.1 2093582 R 405955 CDS YP_853072.1 117624159 4492533 complement(2094855..2096684) 1 NC_008563.1 ABC transporter 2096684 4492533 APECO1_1055 Escherichia coli APEC O1 ABC transporter YP_853072.1 2094855 R 405955 CDS YP_853073.1 117624160 4492534 complement(2096644..2098446) 1 NC_008563.1 inner membrane ABC-transporter 2098446 ybtP 4492534 ybtP Escherichia coli APEC O1 inner membrane ABC-transporter YP_853073.1 2096644 R 405955 CDS YP_853074.1 117624161 4492535 2098613..2099572 1 NC_008563.1 AraC family transcriptional regulator 2099572 4492535 APECO1_1057 Escherichia coli APEC O1 AraC family transcriptional regulator YP_853074.1 2098613 D 405955 CDS YP_853075.1 117624162 4492536 2099745..2105870 1 NC_008563.1 yersiniabactin biosynthetic protein 2105870 irp2 4492536 irp2 Escherichia coli APEC O1 yersiniabactin biosynthetic protein YP_853075.1 2099745 D 405955 CDS YP_853076.1 117624163 4492537 2105958..2115119 1 NC_008563.1 yersiniabactin biosynthetic protein 2115119 irp1 4492537 irp1 Escherichia coli APEC O1 yersiniabactin biosynthetic protein YP_853076.1 2105958 D 405955 CDS YP_853077.1 117624164 4492538 2115444..2116544 1 NC_008563.1 yersiniabactin biosynthetic protein 2116544 ybtU 4492538 ybtU Escherichia coli APEC O1 yersiniabactin biosynthetic protein YP_853077.1 2115444 D 405955 CDS YP_853078.1 117624165 4492539 2116541..2117344 1 NC_008563.1 yersiniabactin biosynthetic protein YbtT 2117344 ybtT 4492539 ybtT Escherichia coli APEC O1 yersiniabactin biosynthetic protein YbtT YP_853078.1 2116541 D 405955 CDS YP_853079.1 117624166 4492540 2117348..2118925 1 NC_008563.1 yersiniabactin siderophore biosynthetic protein 2118925 ybtE 4492540 ybtE Escherichia coli APEC O1 yersiniabactin siderophore biosynthetic protein YP_853079.1 2117348 D 405955 CDS YP_853080.1 117624167 4492541 2119056..2121077 1 NC_008563.1 pesticin/yersiniabactin receptor protein 2121077 fyuA 4492541 fyuA Escherichia coli APEC O1 pesticin/yersiniabactin receptor protein YP_853080.1 2119056 D 405955 CDS YP_853081.1 117624168 4492542 2121671..2122477 1 NC_008563.1 hypothetical protein 2122477 4492542 APECO1_1064 Escherichia coli APEC O1 hypothetical protein YP_853081.1 2121671 D 405955 CDS YP_853082.1 117624169 4492543 2122610..2124568 1 NC_008563.1 autotransporter 2124568 4492543 APECO1_1065 Escherichia coli APEC O1 autotransporter YP_853082.1 2122610 D 405955 CDS YP_853083.1 117624170 4492544 complement(2124696..2125748) 1 NC_008563.1 hypothetical protein 2125748 4492544 APECO1_1066 Escherichia coli APEC O1 hypothetical protein YP_853083.1 2124696 R 405955 CDS YP_853084.1 117624171 4492545 2126063..2127379 1 NC_008563.1 shikimate transporter 2127379 4492545 APECO1_1067 Escherichia coli APEC O1 shikimate transporter YP_853084.1 2126063 D 405955 CDS YP_853085.1 117624172 4492546 2127433..2128935 1 NC_008563.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2128935 amn 4492546 amn Escherichia coli APEC O1 AMP nucleosidase YP_853085.1 2127433 D 405955 CDS YP_853086.1 117624173 4492547 2129278..2129994 1 NC_008563.1 hypothetical protein 2129994 4492547 APECO1_1069 Escherichia coli APEC O1 hypothetical protein YP_853086.1 2129278 D 405955 CDS YP_853087.1 117624174 4492548 complement(2130050..2130337) 1 NC_008563.1 hypothetical protein 2130337 4492548 APECO1_1070 Escherichia coli APEC O1 hypothetical protein YP_853087.1 2130050 R 405955 CDS YP_853088.1 117624175 4492549 complement(2130624..2132114) 1 NC_008563.1 hypothetical protein 2132114 yeeO 4492549 yeeO Escherichia coli APEC O1 hypothetical protein YP_853088.1 2130624 R 405955 CDS YP_853089.1 117624176 4492550 complement(2132388..2133338) 1 NC_008563.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2133338 cbl 4492550 cbl Escherichia coli APEC O1 transcriptional regulator Cbl YP_853089.1 2132388 R 405955 CDS YP_853090.1 117624177 4492551 complement(2133440..2134357) 1 NC_008563.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2134357 nac 4492551 nac Escherichia coli APEC O1 nitrogen assimilation transcriptional regulator YP_853090.1 2133440 R 405955 CDS YP_853091.1 117624178 4492552 complement(2134815..2135750) 1 NC_008563.1 hypothetical protein 2135750 erfK 4492552 erfK Escherichia coli APEC O1 hypothetical protein YP_853091.1 2134815 R 405955 CDS YP_853092.1 117624179 4492553 complement(2135812..2136891) 1 NC_008563.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2136891 cobT 4492553 cobT Escherichia coli APEC O1 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_853092.1 2135812 R 405955 CDS YP_853093.1 117624180 4492554 complement(2136903..2137682) 1 NC_008563.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2137682 cobS 4492554 cobS Escherichia coli APEC O1 cobalamin synthase YP_853093.1 2136903 R 405955 CDS YP_853094.1 117624181 4492555 complement(2137643..2138188) 1 NC_008563.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 2138188 cobU 4492555 cobU Escherichia coli APEC O1 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_853094.1 2137643 R 405955 CDS YP_853095.1 117624182 4492556 complement(2140861..2141175) 1 NC_008563.1 hypothetical protein 2141175 4492556 APECO1_1075 Escherichia coli APEC O1 hypothetical protein YP_853095.1 2140861 R 405955 CDS YP_853096.1 117624183 4492557 2141294..2142508 1 NC_008563.1 carbohydrate kinase 2142508 4492557 APECO1_1076 Escherichia coli APEC O1 carbohydrate kinase YP_853096.1 2141294 D 405955 CDS YP_853097.1 117624184 4492558 2142522..2143280 1 NC_008563.1 hypothetical protein 2143280 4492558 APECO1_1077 Escherichia coli APEC O1 hypothetical protein YP_853097.1 2142522 D 405955 CDS YP_853098.1 117624185 4492559 2143337..2144302 1 NC_008563.1 hypothetical protein 2144302 4492559 APECO1_1078 Escherichia coli APEC O1 hypothetical protein YP_853098.1 2143337 D 405955 CDS YP_853099.1 117624186 4492560 2144305..2145339 1 NC_008563.1 phosphotriesterase-related protein 2145339 4492560 APECO1_1079 Escherichia coli APEC O1 phosphotriesterase-related protein YP_853099.1 2144305 D 405955 CDS YP_853100.1 117624187 4492561 complement(2145991..2146974) 1 NC_008563.1 transposase 2146974 4492561 APECO1_1080 Escherichia coli APEC O1 transposase YP_853100.1 2145991 R 405955 CDS YP_853101.1 117624188 4492776 complement(2147032..2147370) 1 NC_008563.1 hypothetical protein 2147370 4492776 APECO1_1081 Escherichia coli APEC O1 hypothetical protein YP_853101.1 2147032 R 405955 CDS YP_853102.1 117624189 4492777 complement(2147654..2148148) 1 NC_008563.1 hypothetical protein 2148148 4492777 APECO1_1082 Escherichia coli APEC O1 hypothetical protein YP_853102.1 2147654 R 405955 CDS YP_853103.1 117624190 4492778 complement(2148049..2148456) 1 NC_008563.1 hypothetical protein 2148456 4492778 APECO1_1083 Escherichia coli APEC O1 hypothetical protein YP_853103.1 2148049 R 405955 CDS YP_853104.1 117624191 4492779 complement(2148710..2149315) 1 NC_008563.1 hypothetical protein 2149315 4492779 APECO1_1084 Escherichia coli APEC O1 hypothetical protein YP_853104.1 2148710 R 405955 CDS YP_853105.1 117624192 4492780 2150106..2150429 1 NC_008563.1 hypothetical protein 2150429 4492780 APECO1_1085 Escherichia coli APEC O1 hypothetical protein YP_853105.1 2150106 D 405955 CDS YP_853106.1 117624193 4492781 2150605..2151012 1 NC_008563.1 transcriptional regulator 2151012 4492781 APECO1_1086 Escherichia coli APEC O1 transcriptional regulator YP_853106.1 2150605 D 405955 CDS YP_853107.1 117624194 4492782 2151091..2151708 1 NC_008563.1 hypothetical protein 2151708 4492782 APECO1_1087 Escherichia coli APEC O1 hypothetical protein YP_853107.1 2151091 D 405955 CDS YP_853108.1 117624195 4492783 complement(2152251..2153102) 1 NC_008563.1 transposase subunit 2153102 4492783 APECO1_1088 Escherichia coli APEC O1 transposase subunit YP_853108.1 2152251 R 405955 CDS YP_853109.1 117624196 4492784 complement(2153099..2153620) 1 NC_008563.1 transposase subunit 2153620 4492784 APECO1_1089 Escherichia coli APEC O1 transposase subunit YP_853109.1 2153099 R 405955 CDS YP_853110.1 117624197 4492785 2154070..2154345 1 NC_008563.1 transposase subunit 2154345 4492785 APECO1_1090 Escherichia coli APEC O1 transposase subunit YP_853110.1 2154070 D 405955 CDS YP_853111.1 117624198 4492786 complement(2154572..2154916) 1 NC_008563.1 hypothetical protein 2154916 4492786 APECO1_1091 Escherichia coli APEC O1 hypothetical protein YP_853111.1 2154572 R 405955 CDS YP_853112.1 117624199 4492787 2155537..2156700 1 NC_008563.1 hypothetical protein 2156700 4492787 APECO1_1092 Escherichia coli APEC O1 hypothetical protein YP_853112.1 2155537 D 405955 CDS YP_853113.1 117624200 4492788 2156745..2157656 1 NC_008563.1 hypothetical protein 2157656 4492788 APECO1_1093 Escherichia coli APEC O1 hypothetical protein YP_853113.1 2156745 D 405955 CDS YP_853114.1 117624201 4492789 2157874..2160270 1 NC_008563.1 hypothetical protein 2160270 4492789 APECO1_1094 Escherichia coli APEC O1 hypothetical protein YP_853114.1 2157874 D 405955 CDS YP_853115.1 117624202 4492790 2160267..2161172 1 NC_008563.1 hypothetical protein 2161172 4492790 APECO1_1095 Escherichia coli APEC O1 hypothetical protein YP_853115.1 2160267 D 405955 CDS YP_853116.1 117624203 4492791 2161169..2162239 1 NC_008563.1 esterase 2162239 4492791 APECO1_1097 Escherichia coli APEC O1 esterase YP_853116.1 2161169 D 405955 CDS YP_853117.1 117624204 4492792 2162267..2163058 1 NC_008563.1 hypothetical protein 2163058 4492792 APECO1_1098 Escherichia coli APEC O1 hypothetical protein YP_853117.1 2162267 D 405955 CDS YP_853118.1 117624205 4492793 2163074..2163484 1 NC_008563.1 hypothetical protein 2163484 4492793 APECO1_1099 Escherichia coli APEC O1 hypothetical protein YP_853118.1 2163074 D 405955 CDS YP_853119.1 117624206 4492794 complement(2163701..2164540) 1 NC_008563.1 hypothetical protein 2164540 4492794 APECO1_1100 Escherichia coli APEC O1 hypothetical protein YP_853119.1 2163701 R 405955 CDS YP_853120.1 117624207 4492795 complement(2164631..2165554) 1 NC_008563.1 hypothetical protein 2165554 4492795 APECO1_1101 Escherichia coli APEC O1 hypothetical protein YP_853120.1 2164631 R 405955 CDS YP_853121.1 117624208 4491734 2165924..2166292 1 NC_008563.1 antitoxin of the YeeV-YeeU toxin-antitoxin system 2166292 yeeU 4491734 yeeU Escherichia coli APEC O1 antitoxin of the YeeV-YeeU toxin-antitoxin system YP_853121.1 2165924 D 405955 CDS YP_853122.1 117624209 4491735 2166381..2166644 1 NC_008563.1 toxin of the YeeV-YeeU toxin-antitoxin system 2166644 yeeV 4491735 yeeV Escherichia coli APEC O1 toxin of the YeeV-YeeU toxin-antitoxin system YP_853122.1 2166381 D 405955 CDS YP_853123.1 117624210 4491736 2167386..2167742 1 NC_008563.1 hypothetical protein 2167742 yoeF 4491736 yoeF Escherichia coli APEC O1 hypothetical protein YP_853123.1 2167386 D 405955 CDS YP_853124.1 117624211 4491737 complement(2167843..2168238) 1 NC_008563.1 hypothetical protein 2168238 yeeX 4491737 yeeX Escherichia coli APEC O1 hypothetical protein YP_853124.1 2167843 R 405955 CDS YP_853125.1 117624212 4491738 complement(2168344..2169402) 1 NC_008563.1 hypothetical protein 2169402 yeeA 4491738 yeeA Escherichia coli APEC O1 hypothetical protein YP_853125.1 2168344 R 405955 CDS YP_853126.1 117624213 4491739 complement(2169600..2170073) 1 NC_008563.1 DNA gyrase inhibitor 2170073 sbmC 4491739 sbmC Escherichia coli APEC O1 DNA gyrase inhibitor YP_853126.1 2169600 R 405955 CDS YP_853127.1 117624214 4491740 complement(2170192..2171235) 1 NC_008563.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2171235 dacD 4491740 dacD Escherichia coli APEC O1 D-alanyl-D-alanine carboxypeptidase YP_853127.1 2170192 R 405955 CDS YP_853128.1 117624215 4491741 2171519..2172994 1 NC_008563.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2172994 sbcB 4491741 sbcB Escherichia coli APEC O1 exonuclease I YP_853128.1 2171519 D 405955 CDS YP_853129.1 117624216 4491742 complement(2173278..2174336) 1 NC_008563.1 hypothetical protein 2174336 yeeE 4491742 yeeE Escherichia coli APEC O1 hypothetical protein YP_853129.1 2173278 R 405955 CDS YP_853130.1 117624217 4491743 complement(2174515..2175879) 1 NC_008563.1 amino acid transporter 2175879 yeeF 4491743 yeeF Escherichia coli APEC O1 amino acid transporter YP_853130.1 2174515 R 405955 CDS YP_853131.1 117624218 4491744 complement(2176140..2177090) 1 NC_008563.1 DNA-binding transcriptional regulator 2177090 yeeY 4491744 yeeY Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_853131.1 2176140 R 405955 CDS YP_853132.1 117624219 4491745 complement(2177115..2177939) 1 NC_008563.1 epimerase 2177939 yeeZ 4491745 yeeZ Escherichia coli APEC O1 epimerase YP_853132.1 2177115 R 405955 CDS YP_853133.1 117624220 4491746 complement(2178022..2178276) 1 NC_008563.1 hypothetical protein 2178276 4491746 APECO1_1114 Escherichia coli APEC O1 hypothetical protein YP_853133.1 2178022 R 405955 CDS YP_853134.1 117624221 4491747 complement(2178273..2178551) 1 NC_008563.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2178551 yefM 4491747 yefM Escherichia coli APEC O1 antitoxin YefM YP_853134.1 2178273 R 405955 CDS YP_853135.1 117624222 4491748 2178994..2179893 1 NC_008563.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2179893 hisG 4491748 hisG Escherichia coli APEC O1 ATP phosphoribosyltransferase YP_853135.1 2178994 D 405955 CDS YP_853136.1 117624223 4491749 2179890..2181203 1 NC_008563.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2181203 hisD 4491749 hisD Escherichia coli APEC O1 histidinol dehydrogenase YP_853136.1 2179890 D 405955 CDS YP_853137.1 117624224 4491750 2181200..2182270 1 NC_008563.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2182270 hisC 4491750 hisC Escherichia coli APEC O1 histidinol-phosphate aminotransferase YP_853137.1 2181200 D 405955 CDS YP_853138.1 117624225 4491751 2182270..2183337 1 NC_008563.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2183337 hisB 4491751 hisB Escherichia coli APEC O1 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_853138.1 2182270 D 405955 CDS YP_853139.1 117624226 4491752 2183337..2183927 1 NC_008563.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2183927 hisH 4491752 hisH Escherichia coli APEC O1 imidazole glycerol phosphate synthase subunit HisH YP_853139.1 2183337 D 405955 CDS YP_853140.1 117624227 4491830 2183924..2184664 1 NC_008563.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2184664 hisA 4491830 hisA Escherichia coli APEC O1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_853140.1 2183924 D 405955 CDS YP_853141.1 117624228 4491831 2184646..2185422 1 NC_008563.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2185422 hisF 4491831 hisF Escherichia coli APEC O1 imidazole glycerol phosphate synthase subunit HisF YP_853141.1 2184646 D 405955 CDS YP_853142.1 117624229 4491832 2185416..2186027 1 NC_008563.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2186027 hisI 4491832 hisI Escherichia coli APEC O1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_853142.1 2185416 D 405955 CDS YP_853143.1 117624230 4491833 complement(2186123..2187139) 1 NC_008563.1 regulator of length of O-antigen component of lipopolysaccharide chains 2187139 cld 4491833 cld Escherichia coli APEC O1 regulator of length of O-antigen component of lipopolysaccharide chains YP_853143.1 2186123 R 405955 CDS YP_853144.1 117624231 4491834 complement(2187249..2188415) 1 NC_008563.1 UDP-glucose 6-dehydrogenase 2188415 ugd 4491834 ugd Escherichia coli APEC O1 UDP-glucose 6-dehydrogenase YP_853144.1 2187249 R 405955 CDS YP_853145.1 117624232 4491835 complement(2188663..2190069) 1 NC_008563.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2190069 gnd 4491835 gnd Escherichia coli APEC O1 6-phosphogluconate dehydrogenase YP_853145.1 2188663 R 405955 CDS YP_853146.1 117624233 4491838 complement(2195479..2196705) 1 NC_008563.1 O-antigen transporter 2196705 4491838 APECO1_1127 Escherichia coli APEC O1 O-antigen transporter YP_853146.1 2195479 R 405955 CDS YP_853147.1 117624234 4491839 complement(2196749..2197297) 1 NC_008563.1 dTDP-4-dehydrorhamnose 3,5-epimerase 2197297 rmlC 4491839 rmlC Escherichia coli APEC O1 dTDP-4-dehydrorhamnose 3,5-epimerase YP_853147.1 2196749 R 405955 CDS YP_853148.1 117624235 4491840 complement(2197302..2198180) 1 NC_008563.1 glucose-1-phosphate thymidylyltransferase 2198180 rmlA 4491840 rmlA Escherichia coli APEC O1 glucose-1-phosphate thymidylyltransferase YP_853148.1 2197302 R 405955 CDS YP_853149.1 117624236 4491841 complement(2198238..2199137) 1 NC_008563.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 2199137 rmlD 4491841 rmlD Escherichia coli APEC O1 dTDP-4-dehydrorhamnose reductase YP_853149.1 2198238 R 405955 CDS YP_853150.1 117624237 4491842 complement(2199137..2200222) 1 NC_008563.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase 2200222 rfbB 4491842 rfbB Escherichia coli APEC O1 dTDP-glucose-4,6-dehydratase YP_853150.1 2199137 R 405955 CDS YP_853151.1 117624238 4491843 complement(2200595..2201500) 1 NC_008563.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 2201500 galF 4491843 galF Escherichia coli APEC O1 UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_853151.1 2200595 R 405955 CDS YP_853152.1 117624239 4491844 complement(2201663..2203057) 1 NC_008563.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2203057 wcaM 4491844 wcaM Escherichia coli APEC O1 colanic acid biosynthesis protein YP_853152.1 2201663 R 405955 CDS YP_853153.1 117624240 4491845 complement(2203068..2204288) 1 NC_008563.1 colanic acid biosynthesis glycosyl transferase 2204288 wcaL 4491845 wcaL Escherichia coli APEC O1 colanic acid biosynthesis glycosyl transferase YP_853153.1 2203068 R 405955 CDS YP_853154.1 117624241 4491846 complement(2204285..2205565) 1 NC_008563.1 pyruvyl transferase 2205565 wcaK 4491846 wcaK Escherichia coli APEC O1 pyruvyl transferase YP_853154.1 2204285 R 405955 CDS YP_853155.1 117624242 4491847 complement(2205727..2207205) 1 NC_008563.1 colanic acid exporter 2207205 wzxC 4491847 wzxC Escherichia coli APEC O1 colanic acid exporter YP_853155.1 2205727 R 405955 CDS YP_853156.1 117624243 4491848 complement(2207207..2208601) 1 NC_008563.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2208601 wcaJ 4491848 wcaJ Escherichia coli APEC O1 UDP-glucose lipid carrier transferase YP_853156.1 2207207 R 405955 CDS YP_853157.1 117624244 4491849 complement(2208656..2210026) 1 NC_008563.1 phosphomannomutase 2210026 cpsG 4491849 cpsG Escherichia coli APEC O1 phosphomannomutase YP_853157.1 2208656 R 405955 CDS YP_853158.1 117624245 4494487 complement(2210128..2211564) 1 NC_008563.1 mannose-1-phosphate guanylyltransferase 2211564 cpsB 4494487 cpsB Escherichia coli APEC O1 mannose-1-phosphate guanylyltransferase YP_853158.1 2210128 R 405955 CDS YP_853159.1 117624246 4494488 complement(2211567..2212790) 1 NC_008563.1 glycosyl transferase family protein 2212790 wcaI 4494488 wcaI Escherichia coli APEC O1 glycosyl transferase family protein YP_853159.1 2211567 R 405955 CDS YP_853160.1 117624247 4494489 complement(2212787..2213269) 1 NC_008563.1 GDP-mannose mannosyl hydrolase 2213269 wcaH 4494489 wcaH Escherichia coli APEC O1 GDP-mannose mannosyl hydrolase YP_853160.1 2212787 R 405955 CDS YP_853161.1 117624248 4494490 complement(2213269..2214234) 1 NC_008563.1 GDP-fucose synthetase 2214234 wcaG 4494490 wcaG Escherichia coli APEC O1 GDP-fucose synthetase YP_853161.1 2213269 R 405955 CDS YP_853162.1 117624249 4494491 complement(2214237..2215358) 1 NC_008563.1 GDP-mannose 4,6-dehydratase 2215358 gmd 4494491 gmd Escherichia coli APEC O1 GDP-mannose 4,6-dehydratase YP_853162.1 2214237 R 405955 CDS YP_853163.1 117624250 4494492 complement(2215385..2215933) 1 NC_008563.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2215933 wcaF 4494492 wcaF Escherichia coli APEC O1 colanic acid biosynthesis acetyltransferase WcaF YP_853163.1 2215385 R 405955 CDS YP_853164.1 117624251 4494493 complement(2215949..2216695) 1 NC_008563.1 glycosyl transferase family protein 2216695 wcaE 4494493 wcaE Escherichia coli APEC O1 glycosyl transferase family protein YP_853164.1 2215949 R 405955 CDS YP_853165.2 229775966 4494494 complement(2216776..2217996) 1 NC_008563.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2217996 wcaD 4494494 wcaD Escherichia coli APEC O1 colanic acid biosynthesis protein YP_853165.2 2216776 R 405955 CDS YP_853166.1 117624253 4494495 complement(2217971..2219188) 1 NC_008563.1 glycosyl transferase family protein 2219188 wcaC 4494495 wcaC Escherichia coli APEC O1 glycosyl transferase family protein YP_853166.1 2217971 R 405955 CDS YP_853167.1 117624254 4494496 complement(2219185..2219673) 1 NC_008563.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2219673 wcaB 4494496 wcaB Escherichia coli APEC O1 colanic acid biosynthesis acetyltransferase WcaB YP_853167.1 2219185 R 405955 CDS YP_853168.1 117624255 4494497 complement(2219676..2220515) 1 NC_008563.1 glycosyl transferase family protein 2220515 wcaA 4494497 wcaA Escherichia coli APEC O1 glycosyl transferase family protein YP_853168.1 2219676 R 405955 CDS YP_853169.1 117624256 4494498 complement(2220644..2222842) 1 NC_008563.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2222842 wzc 4494498 wzc Escherichia coli APEC O1 tyrosine kinase YP_853169.1 2220644 R 405955 CDS YP_853170.1 117624257 4494499 complement(2222809..2223252) 1 NC_008563.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2223252 wzb 4494499 wzb Escherichia coli APEC O1 tyrosine phosphatase YP_853170.1 2222809 R 405955 CDS YP_853171.1 117624258 4494500 complement(2223258..2224397) 1 NC_008563.1 polysaccharide export protein 2224397 wza 4494500 wza Escherichia coli APEC O1 polysaccharide export protein YP_853171.1 2223258 R 405955 CDS YP_853172.1 117624259 4494501 2225017..2226639 1 NC_008563.1 hypothetical protein 2226639 yegH 4494501 yegH Escherichia coli APEC O1 hypothetical protein YP_853172.1 2225017 D 405955 CDS YP_853173.1 117624260 4494502 2226714..2227052 1 NC_008563.1 hypothetical protein 2227052 4494502 APECO1_1154 Escherichia coli APEC O1 hypothetical protein YP_853173.1 2226714 D 405955 CDS YP_853174.1 117624261 4494503 complement(2227385..2229238) 1 NC_008563.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2229238 asmA 4494503 asmA Escherichia coli APEC O1 assembly protein YP_853174.1 2227385 R 405955 CDS YP_853175.1 117624262 4494504 complement(2229260..2229841) 1 NC_008563.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2229841 dcd 4494504 dcd Escherichia coli APEC O1 deoxycytidine triphosphate deaminase YP_853175.1 2229260 R 405955 CDS YP_853176.1 117624263 4494505 complement(2229933..2230574) 1 NC_008563.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2230574 udk 4494505 udk Escherichia coli APEC O1 uridine kinase YP_853176.1 2229933 R 405955 CDS YP_853177.1 117624264 4494349 2230892..2234209 1 NC_008563.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2234209 yegE 4494349 yegE Escherichia coli APEC O1 sensor protein YP_853177.1 2230892 D 405955 CDS YP_853178.1 117624265 4494350 complement(2234320..2235168) 1 NC_008563.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2235168 alkA 4494350 alkA Escherichia coli APEC O1 3-methyladenine DNA glycosylase YP_853178.1 2234320 R 405955 CDS YP_853179.1 117624266 4494351 2235302..2236654 1 NC_008563.1 chaperone 2236654 yegD 4494351 yegD Escherichia coli APEC O1 chaperone YP_853179.1 2235302 D 405955 CDS YP_853180.1 117624267 4494352 complement(2236667..2238616) 1 NC_008563.1 hypothetical protein 2238616 yedI 4494352 yedI Escherichia coli APEC O1 hypothetical protein YP_853180.1 2236667 R 405955 CDS YP_853181.1 117624268 4494353 complement(2238604..2239365) 1 NC_008563.1 hypothetical protein 2239365 yedK 4494353 yedK Escherichia coli APEC O1 hypothetical protein YP_853181.1 2238604 R 405955 CDS YP_853182.1 117624269 4494354 complement(2239362..2240021) 1 NC_008563.1 hypothetical protein 2240021 yedL 4494354 yedL Escherichia coli APEC O1 hypothetical protein YP_853182.1 2239362 R 405955 CDS YP_853183.1 117624270 4494355 2240755..2242149 1 NC_008563.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2242149 yegM 4494355 yegM Escherichia coli APEC O1 multidrug efflux system subunit MdtA YP_853183.1 2240755 D 405955 CDS YP_853184.1 117624271 4494356 2242149..2245271 1 NC_008563.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2245271 yegN 4494356 yegN Escherichia coli APEC O1 multidrug efflux system subunit MdtB YP_853184.1 2242149 D 405955 CDS YP_853185.1 117624272 4494357 2245272..2248349 1 NC_008563.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2248349 yegO 4494357 yegO Escherichia coli APEC O1 multidrug efflux system subunit MdtC YP_853185.1 2245272 D 405955 CDS YP_853186.1 117624273 4494358 2248350..2249765 1 NC_008563.1 multidrug efflux system protein MdtE 2249765 yegB 4494358 yegB Escherichia coli APEC O1 multidrug efflux system protein MdtE YP_853186.1 2248350 D 405955 CDS YP_853187.1 117624274 4494359 2249762..2251165 1 NC_008563.1 signal transduction histidine-protein kinase BaeS 2251165 baeS 4494359 baeS Escherichia coli APEC O1 signal transduction histidine-protein kinase BaeS YP_853187.1 2249762 D 405955 CDS YP_853188.1 117624275 4494360 2251162..2251884 1 NC_008563.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2251884 4494360 APECO1_1169 Escherichia coli APEC O1 DNA-binding transcriptional regulator BaeR YP_853188.1 2251162 D 405955 CDS YP_853189.1 117624276 4494361 2252025..2252396 1 NC_008563.1 hypothetical protein 2252396 yegP 4494361 yegP Escherichia coli APEC O1 hypothetical protein YP_853189.1 2252025 D 405955 CDS YP_853190.1 117624277 4494362 complement(2252521..2253135) 1 NC_008563.1 hypothetical protein 2253135 4494362 APECO1_1171 Escherichia coli APEC O1 hypothetical protein YP_853190.1 2252521 R 405955 CDS YP_853191.1 117624278 4494363 complement(2253187..2253495) 1 NC_008563.1 hypothetical protein 2253495 4494363 APECO1_1172 Escherichia coli APEC O1 hypothetical protein YP_853191.1 2253187 R 405955 CDS YP_853192.1 117624279 4494364 complement(2253621..2255333) 1 NC_008563.1 hypothetical protein 2255333 4494364 APECO1_1173 Escherichia coli APEC O1 hypothetical protein YP_853192.1 2253621 R 405955 CDS YP_853193.1 117624280 4494365 complement(2255305..2256021) 1 NC_008563.1 hypothetical protein 2256021 4494365 APECO1_1174 Escherichia coli APEC O1 hypothetical protein YP_853193.1 2255305 R 405955 CDS YP_853194.1 117624281 4494366 complement(2256021..2257235) 1 NC_008563.1 hypothetical protein 2257235 4494366 APECO1_1175 Escherichia coli APEC O1 hypothetical protein YP_853194.1 2256021 R 405955 CDS YP_853195.1 117624282 4494367 2257723..2259084 1 NC_008563.1 hypothetical protein 2259084 yegQ 4494367 yegQ Escherichia coli APEC O1 hypothetical protein YP_853195.1 2257723 D 405955 CDS YP_853196.1 117624283 4494368 complement(2259657..2260820) 1 NC_008563.1 phage protein D 2260820 4494368 APECO1_1177 Escherichia coli APEC O1 phage protein D YP_853196.1 2259657 R 405955 CDS YP_853197.1 117624284 4493927 complement(2260820..2261299) 1 NC_008563.1 phage protein U 2261299 4493927 APECO1_1178 Escherichia coli APEC O1 phage protein U YP_853197.1 2260820 R 405955 CDS YP_853198.1 117624285 4493928 complement(2261314..2263761) 1 NC_008563.1 phage related tail protein 2263761 4493928 APECO1_1179 Escherichia coli APEC O1 phage related tail protein YP_853198.1 2261314 R 405955 CDS YP_853199.1 117624286 4493929 2270959..2272731 1 NC_008563.1 Phage protein P 2272731 gpP 4493929 gpP Escherichia coli APEC O1 Phage protein P YP_853199.1 2270959 D 405955 CDS YP_853200.1 117624287 4493930 2272731..2273765 1 NC_008563.1 Phage protein Q 2273765 gpQ 4493930 gpQ Escherichia coli APEC O1 Phage protein Q YP_853200.1 2272731 D 405955 CDS YP_853201.1 117624288 4493931 2274092..2275141 1 NC_008563.1 hypothetical protein 2275141 4493931 APECO1_1182 Escherichia coli APEC O1 hypothetical protein YP_853201.1 2274092 D 405955 CDS YP_853202.1 117624289 4493932 2275134..2276417 1 NC_008563.1 hypothetical protein 2276417 4493932 APECO1_1183 Escherichia coli APEC O1 hypothetical protein YP_853202.1 2275134 D 405955 CDS YP_853203.1 117624290 4493933 complement(2276593..2278848) 1 NC_008563.1 Phage protein A 2278848 gpA 4493933 gpA Escherichia coli APEC O1 Phage protein A YP_853203.1 2276593 R 405955 CDS YP_853204.1 117624291 4493934 complement(2279337..2279636) 1 NC_008563.1 hypothetical protein 2279636 4493934 APECO1_1185 Escherichia coli APEC O1 hypothetical protein YP_853204.1 2279337 R 405955 CDS YP_853205.1 117624292 4493935 complement(2279924..2280430) 1 NC_008563.1 Phage protein B 2280430 gpB 4493935 gpB Escherichia coli APEC O1 Phage protein B YP_853205.1 2279924 R 405955 CDS YP_853206.1 117624293 4493936 2280992..2281291 1 NC_008563.1 phage-associated; immunity repressor 2281291 gpC 4493936 gpC Escherichia coli APEC O1 immunity repressor YP_853206.1 2280992 D 405955 CDS YP_853207.1 117624294 4493937 2281407..2282420 1 NC_008563.1 phage integrase 2282420 4493937 APECO1_4458 Escherichia coli APEC O1 phage integrase YP_853207.1 2281407 D 405955 CDS YP_853208.1 117624295 4493938 complement(2282855..2283232) 1 NC_008563.1 hypothetical protein 2283232 yegR 4493938 yegR Escherichia coli APEC O1 hypothetical protein YP_853208.1 2282855 R 405955 CDS YP_853209.1 117624296 4493939 2283588..2284487 1 NC_008563.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2284487 4493939 APECO1_4456 Escherichia coli APEC O1 lipid kinase YP_853209.1 2283588 D 405955 CDS YP_853210.1 117624297 4493940 complement(2284569..2285348) 1 NC_008563.1 galactitol utilization operon repressor 2285348 gatR 4493940 gatR Escherichia coli APEC O1 galactitol utilization operon repressor YP_853210.1 2284569 R 405955 CDS YP_853211.1 117624298 4493941 complement(2285448..2286488) 1 NC_008563.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2286488 gatD 4493941 gatD Escherichia coli APEC O1 galactitol-1-phosphate dehydrogenase YP_853211.1 2285448 R 405955 CDS YP_853212.1 117624299 4493942 complement(2286536..2287891) 1 NC_008563.1 PTS system galactitol-specific transporter subunit IIC 2287891 gatC 4493942 gatC Escherichia coli APEC O1 PTS system galactitol-specific transporter subunit IIC YP_853212.1 2286536 R 405955 CDS YP_853213.1 117624300 4493943 complement(2287895..2288179) 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2288179 gatB 4493943 gatB Escherichia coli APEC O1 PTS system galactitol-specific transporter subunit IIB YP_853213.1 2287895 R 405955 CDS YP_853214.1 117624301 4493944 complement(2288210..2288662) 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2288662 gatA 4493944 gatA Escherichia coli APEC O1 PTS system galactitol-specific transporter subunit IIA YP_853214.1 2288210 R 405955 CDS YP_853215.1 117624302 4493945 complement(2288672..2289934) 1 NC_008563.1 tagatose 6-phosphate kinase GatZ 2289934 gatZ 4493945 gatZ Escherichia coli APEC O1 tagatose 6-phosphate kinase GatZ YP_853215.1 2288672 R 405955 CDS YP_853216.1 117624303 4494506 complement(2289963..2290817) 1 NC_008563.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2290817 gatY 4494506 gatY Escherichia coli APEC O1 tagatose-bisphosphate aldolase YP_853216.1 2289963 R 405955 CDS YP_853217.1 117624304 4494507 complement(2291046..2292170) 1 NC_008563.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2292170 4494507 APECO1_4448 Escherichia coli APEC O1 fructose-bisphosphate aldolase YP_853217.1 2291046 R 405955 CDS YP_853218.1 117624305 4494508 2292355..2293632 1 NC_008563.1 nucleoside transporter 2293632 yegT 4494508 yegT Escherichia coli APEC O1 nucleoside transporter YP_853218.1 2292355 D 405955 CDS YP_853219.1 117624306 4494509 2293629..2294633 1 NC_008563.1 hydrolase 2294633 yegW 4494509 yegW Escherichia coli APEC O1 hydrolase YP_853219.1 2293629 D 405955 CDS YP_853220.1 117624307 4494510 2294630..2295595 1 NC_008563.1 sugar kinase 2295595 yegV 4494510 yegV Escherichia coli APEC O1 sugar kinase YP_853220.1 2294630 D 405955 CDS YP_853221.1 117624308 4494511 complement(2295569..2296315) 1 NC_008563.1 transcriptional regulator 2296315 yegW 4494511 yegW Escherichia coli APEC O1 transcriptional regulator YP_853221.1 2295569 R 405955 CDS YP_853222.1 117624309 4494512 complement(2296367..2297194) 1 NC_008563.1 hypothetical protein 2297194 yegX 4494512 yegX Escherichia coli APEC O1 hypothetical protein YP_853222.1 2296367 R 405955 CDS YP_853223.1 117624310 4494513 complement(2297250..2298050) 1 NC_008563.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2298050 thiD 4494513 thiD Escherichia coli APEC O1 phosphomethylpyrimidine kinase YP_853223.1 2297250 R 405955 CDS YP_853224.1 117624311 4494514 complement(2298047..2298835) 1 NC_008563.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2298835 thiM 4494514 thiM Escherichia coli APEC O1 hydroxyethylthiazole kinase YP_853224.1 2298047 R 405955 CDS YP_853225.1 117624312 4494515 2299451..2300275 1 NC_008563.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2300275 yohL 4494515 yohL Escherichia coli APEC O1 nickel/cobalt efflux protein RcnA YP_853225.1 2299451 D 405955 CDS YP_853226.1 117624313 4494516 2300314..2300832 1 NC_008563.1 hypothetical protein 2300832 yohN 4494516 yohN Escherichia coli APEC O1 hypothetical protein YP_853226.1 2300314 D 405955 CDS YP_853227.1 117624314 4494517 complement(2300914..2301948) 1 NC_008563.1 fimbrial-like adhesin protein 2301948 yehA 4494517 yehA Escherichia coli APEC O1 fimbrial-like adhesin protein YP_853227.1 2300914 R 405955 CDS YP_853228.1 117624315 4494518 complement(2301964..2304444) 1 NC_008563.1 outer membrane usher protein YehB 2304444 yehB 4494518 yehB Escherichia coli APEC O1 outer membrane usher protein YehB YP_853228.1 2301964 R 405955 CDS YP_853229.1 117624316 4494519 complement(2304460..2305134) 1 NC_008563.1 fimbrial chaperone YehC 2305134 yehC 4494519 yehC Escherichia coli APEC O1 fimbrial chaperone YehC YP_853229.1 2304460 R 405955 CDS YP_853230.1 117624317 4494520 complement(2306051..2306332) 1 NC_008563.1 fimbrial-like adhesin protein 2306332 yehD 4494520 yehD Escherichia coli APEC O1 fimbrial-like adhesin protein YP_853230.1 2306051 R 405955 CDS YP_853231.1 117624318 4494521 complement(2306595..2307734) 1 NC_008563.1 ATPase 2307734 mrp 4494521 mrp Escherichia coli APEC O1 ATPase YP_853231.1 2306595 R 405955 CDS YP_853232.1 117624319 4494522 2307827..2309869 1 NC_008563.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2309869 metG 4494522 metG Escherichia coli APEC O1 methionyl-tRNA synthetase YP_853232.1 2307827 D 405955 CDS YP_853233.1 117624320 4494523 2310010..2313798 1 NC_008563.1 hypothetical protein 2313798 4494523 APECO1_4432 Escherichia coli APEC O1 hypothetical protein YP_853233.1 2310010 D 405955 CDS YP_853234.1 117624321 4494524 2314086..2317439 1 NC_008563.1 hypothetical protein 2317439 yehI 4494524 yehI Escherichia coli APEC O1 hypothetical protein YP_853234.1 2314086 D 405955 CDS YP_853235.1 117624322 4494525 2318530..2319684 1 NC_008563.1 ATPase 2319684 yehL 4494525 yehL Escherichia coli APEC O1 ATPase YP_853235.1 2318530 D 405955 CDS YP_853236.1 117624323 4494698 2319691..2321967 1 NC_008563.1 hypothetical protein 2321967 yehM 4494698 yehM Escherichia coli APEC O1 hypothetical protein YP_853236.1 2319691 D 405955 CDS YP_853237.1 117624324 4494699 2321750..2323096 1 NC_008563.1 hypothetical protein 2323096 yehN 4494699 yehN Escherichia coli APEC O1 hypothetical protein YP_853237.1 2321750 D 405955 CDS YP_853238.1 117624325 4494700 2323093..2325096 1 NC_008563.1 hypothetical protein 2325096 yehQ 4494700 yehQ Escherichia coli APEC O1 hypothetical protein YP_853238.1 2323093 D 405955 CDS YP_853239.1 117624326 4494701 2325209..2325682 1 NC_008563.1 hypothetical protein 2325682 yehR 4494701 yehR Escherichia coli APEC O1 hypothetical protein YP_853239.1 2325209 D 405955 CDS YP_853240.1 117624327 4494702 complement(2325723..2326193) 1 NC_008563.1 hypothetical protein 2326193 yehS 4494702 yehS Escherichia coli APEC O1 hypothetical protein YP_853240.1 2325723 R 405955 CDS YP_853241.1 117624328 4494703 complement(2326240..2326974) 1 NC_008563.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2326974 yehT 4494703 yehT Escherichia coli APEC O1 two-component response-regulatory protein YehT YP_853241.1 2326240 R 405955 CDS YP_853242.1 117624329 4494704 complement(2326956..2328641) 1 NC_008563.1 sensory kinase in two-component system with YehT 2328641 yehU 4494704 yehU Escherichia coli APEC O1 sensory kinase in two-component system with YehT YP_853242.1 2326956 R 405955 CDS YP_853243.1 117624330 4494705 2328863..2329594 1 NC_008563.1 MerR family transcriptional regulator 2329594 yehV 4494705 yehV Escherichia coli APEC O1 MerR family transcriptional regulator YP_853243.1 2328863 D 405955 CDS YP_853244.1 117624331 4494706 complement(2329742..2330473) 1 NC_008563.1 transporter subunit membrane protein 2330473 yehW 4494706 yehW Escherichia coli APEC O1 transporter subunit membrane protein YP_853244.1 2329742 R 405955 CDS YP_853245.1 117624332 4494707 complement(2330478..2331404) 1 NC_008563.1 transporter subunit ATP-binding protein 2331404 yehX 4494707 yehX Escherichia coli APEC O1 transporter subunit ATP-binding protein YP_853245.1 2330478 R 405955 CDS YP_853246.1 117624333 4494708 complement(2331397..2332554) 1 NC_008563.1 transporter subunit membrane protein 2332554 yehY 4494708 yehY Escherichia coli APEC O1 transporter subunit membrane protein YP_853246.1 2331397 R 405955 CDS YP_853247.1 117624334 4494709 complement(2332561..2333478) 1 NC_008563.1 transporter subunit periplasmic-binding protein 2333478 yehZ 4494709 yehZ Escherichia coli APEC O1 transporter subunit periplasmic-binding protein YP_853247.1 2332561 R 405955 CDS YP_853248.1 117624335 4494710 complement(2333668..2336037) 1 NC_008563.1 beta-D-glucoside glucohydrolase-like protein 2336037 bglX 4494710 bglX Escherichia coli APEC O1 beta-D-glucoside glucohydrolase-like protein YP_853248.1 2333668 R 405955 CDS YP_853249.1 117624336 4494711 2336170..2337876 1 NC_008563.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2337876 dld 4494711 dld Escherichia coli APEC O1 D-lactate dehydrogenase YP_853249.1 2336170 D 405955 CDS YP_853250.1 117624337 4494712 complement(2337915..2338856) 1 NC_008563.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2338856 pbpG 4494712 pbpG Escherichia coli APEC O1 D-alanyl-D-alanine endopeptidase YP_853250.1 2337915 R 405955 CDS YP_853251.1 117624338 4494713 complement(2339021..2339632) 1 NC_008563.1 hypothetical protein 2339632 yohC 4494713 yohC Escherichia coli APEC O1 hypothetical protein YP_853251.1 2339021 R 405955 CDS YP_853252.1 117624339 4494714 2339742..2340356 1 NC_008563.1 hypothetical protein 2340356 yohD 4494714 yohD Escherichia coli APEC O1 hypothetical protein YP_853252.1 2339742 D 405955 CDS YP_853253.1 117624340 4494715 complement(2340476..2341237) 1 NC_008563.1 acetoin dehydrogenase 2341237 yohF 4494715 yohF Escherichia coli APEC O1 acetoin dehydrogenase YP_853253.1 2340476 R 405955 CDS YP_853254.1 117624341 4491636 complement(2341290..2342807) 1 NC_008563.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2342807 yohG 4491636 yohG Escherichia coli APEC O1 multidrug resistance outer membrane protein MdtQ YP_853254.1 2341290 R 405955 CDS YP_853255.1 117624342 4491637 complement(2343421..2344371) 1 NC_008563.1 tRNA-dihydrouridine synthase C 2344371 dusC 4491637 dusC Escherichia coli APEC O1 tRNA-dihydrouridine synthase C YP_853255.1 2343421 R 405955 CDS YP_853256.1 117624343 4491638 2344610..2345008 1 NC_008563.1 hypothetical protein 2345008 yohJ 4491638 yohJ Escherichia coli APEC O1 hypothetical protein YP_853256.1 2344610 D 405955 CDS YP_853257.1 117624344 4491639 2345005..2345700 1 NC_008563.1 hypothetical protein 2345700 yohK 4491639 yohK Escherichia coli APEC O1 hypothetical protein YP_853257.1 2345005 D 405955 CDS YP_853258.1 117624345 4491640 2345830..2346714 1 NC_008563.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2346714 cdd 4491640 cdd Escherichia coli APEC O1 cytidine deaminase YP_853258.1 2345830 D 405955 CDS YP_853259.1 117624346 4491641 2346864..2347583 1 NC_008563.1 hypothetical protein 2347583 sanA 4491641 sanA Escherichia coli APEC O1 hypothetical protein YP_853259.1 2346864 D 405955 CDS YP_853260.1 117624347 4491642 2348019..2349257 1 NC_008563.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2349257 yeiT 4491642 yeiT Escherichia coli APEC O1 oxidoreductase YP_853260.1 2348019 D 405955 CDS YP_853261.1 117624348 4491643 2349251..2350486 1 NC_008563.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2350486 yeiA 4491643 yeiA Escherichia coli APEC O1 dihydropyrimidine dehydrogenase YP_853261.1 2349251 D 405955 CDS YP_853262.1 117624349 4491644 complement(2350729..2351739) 1 NC_008563.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 2351739 mglC 4491644 mglC Escherichia coli APEC O1 beta-methylgalactoside transporter inner membrane protein YP_853262.1 2350729 R 405955 CDS YP_853263.1 117624350 4491645 complement(2351755..2353275) 1 NC_008563.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2353275 mglA 4491645 mglA Escherichia coli APEC O1 galactose/methyl galaxtoside transporter ATP-binding protein YP_853263.1 2351755 R 405955 CDS YP_853264.1 117624351 4491646 complement(2353336..2354334) 1 NC_008563.1 methyl-galactoside transporter subunit MglB 2354334 mglB 4491646 mglB Escherichia coli APEC O1 methyl-galactoside transporter subunit MglB YP_853264.1 2353336 R 405955 CDS YP_853265.1 117624352 4491647 complement(2354614..2355654) 1 NC_008563.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2355654 galS 4491647 galS Escherichia coli APEC O1 DNA-binding transcriptional regulator GalS YP_853265.1 2354614 R 405955 CDS YP_853266.1 117624353 4491648 complement(2355796..2356953) 1 NC_008563.1 hypothetical protein 2356953 4491648 APECO1_4399 Escherichia coli APEC O1 hypothetical protein YP_853266.1 2355796 R 405955 CDS YP_853267.1 117624354 4491649 complement(2356970..2357638) 1 NC_008563.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2357638 folE 4491649 folE Escherichia coli APEC O1 GTP cyclohydrolase I YP_853267.1 2356970 R 405955 CDS YP_853268.1 117624355 4491650 2357896..2358732 1 NC_008563.1 esterase 2358732 yeiG 4491650 yeiG Escherichia coli APEC O1 esterase YP_853268.1 2357896 D 405955 CDS YP_853269.2 229775965 4491651 complement(2358764..2360755) 1 NC_008563.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2360755 cirA 4491651 cirA Escherichia coli APEC O1 colicin I receptor YP_853269.2 2358764 R 405955 CDS YP_853270.1 117624357 4491652 complement(2360961..2362430) 1 NC_008563.1 lysine transporter 2362430 lysP 4491652 lysP Escherichia coli APEC O1 lysine transporter YP_853270.1 2360961 R 405955 CDS YP_853271.1 117624358 4491653 complement(2362635..2363516) 1 NC_008563.1 DNA-binding transcriptional regulator 2363516 yeiE 4491653 yeiE Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_853271.1 2362635 R 405955 CDS YP_853272.1 117624359 4491654 2364738..2365595 1 NC_008563.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2365595 yeiH 4491654 yeiH Escherichia coli APEC O1 endonuclease IV YP_853272.1 2364738 D 405955 CDS YP_853273.1 117624360 4491655 2365599..2366687 1 NC_008563.1 hypothetical protein 2366687 yeiI 4491655 yeiI Escherichia coli APEC O1 hypothetical protein YP_853273.1 2365599 D 405955 CDS YP_853274.1 117624361 4493966 complement(2366955..2367896) 1 NC_008563.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2367896 rihB 4493966 rihB Escherichia coli APEC O1 ribonucleoside hydrolase 2 YP_853274.1 2366955 R 405955 CDS YP_853275.1 117624362 4493967 2368065..2368724 1 NC_008563.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2368724 yeiL 4493967 yeiL Escherichia coli APEC O1 DNA-binding transcriptional activator YeiL YP_853275.1 2368065 D 405955 CDS YP_853276.1 117624363 4493968 complement(2368791..2370041) 1 NC_008563.1 nucleoside transporter 2370041 yeiM 4493968 yeiM Escherichia coli APEC O1 nucleoside transporter YP_853276.1 2368791 R 405955 CDS YP_853277.1 117624364 4493969 complement(2370135..2371073) 1 NC_008563.1 hypothetical protein 2371073 yeiN 4493969 yeiN Escherichia coli APEC O1 hypothetical protein YP_853277.1 2370135 R 405955 CDS YP_853278.1 117624365 4493970 complement(2371061..2372116) 1 NC_008563.1 hypothetical protein 2372116 yeiC 4493970 yeiC Escherichia coli APEC O1 hypothetical protein YP_853278.1 2371061 R 405955 CDS YP_853279.1 117624366 4493971 complement(2372458..2374149) 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 2374149 fruA 4493971 fruA Escherichia coli APEC O1 PTS system fructose-specific transporter subunit IIBC YP_853279.1 2372458 R 405955 CDS YP_853280.1 117624367 4493972 complement(2374166..2375104) 1 NC_008563.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2375104 fruK 4493972 fruK Escherichia coli APEC O1 1-phosphofructokinase YP_853280.1 2374166 R 405955 CDS YP_853281.1 117624368 4493973 complement(2375104..2376234) 1 NC_008563.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 2376234 4493973 APECO1_4385 Escherichia coli APEC O1 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_853281.1 2375104 R 405955 CDS YP_853282.1 117624369 4493974 2376601..2377782 1 NC_008563.1 sugar efflux transporter B 2377782 yeiO 4493974 yeiO Escherichia coli APEC O1 sugar efflux transporter B YP_853282.1 2376601 D 405955 CDS YP_853283.1 117624370 4493975 2377933..2378760 1 NC_008563.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2378760 4493975 APECO1_4383 Escherichia coli APEC O1 elongation factor P YP_853283.1 2377933 D 405955 CDS YP_853284.1 117624371 4493976 2378983..2380449 1 NC_008563.1 dehydrogenase, NAD-dependent 2380449 yeiQ 4493976 yeiQ Escherichia coli APEC O1 dehydrogenase, NAD-dependent YP_853284.1 2378983 D 405955 CDS YP_853285.1 117624372 4493977 2380567..2381553 1 NC_008563.1 hypothetical protein 2381553 yeiR 4493977 yeiR Escherichia coli APEC O1 hypothetical protein YP_853285.1 2380567 D 405955 CDS YP_853286.1 117624373 4493978 2381592..2382305 1 NC_008563.1 undecaprenyl pyrophosphate phosphatase 2382305 yeiU 4493978 yeiU Escherichia coli APEC O1 undecaprenyl pyrophosphate phosphatase YP_853286.1 2381592 D 405955 CDS YP_853287.1 117624374 4493979 2382717..2383283 1 NC_008563.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2383283 spr 4493979 spr Escherichia coli APEC O1 outer membrane lipoprotein YP_853287.1 2382717 D 405955 CDS YP_853288.1 117624375 4493980 2383464..2385020 1 NC_008563.1 hypothetical protein 2385020 4493980 APECO1_4378 Escherichia coli APEC O1 hypothetical protein YP_853288.1 2383464 D 405955 CDS YP_853289.1 117624376 4493981 2385102..2386916 1 NC_008563.1 hypothetical protein 2386916 yejA 4493981 yejA Escherichia coli APEC O1 hypothetical protein YP_853289.1 2385102 D 405955 CDS YP_853290.1 117624377 4493982 2386917..2388011 1 NC_008563.1 oligopeptide transporter subunit 2388011 yejB 4493982 yejB Escherichia coli APEC O1 oligopeptide transporter subunit YP_853290.1 2386917 D 405955 CDS YP_853291.1 117624378 4493983 2388011..2389036 1 NC_008563.1 oligopeptide transporter subunit 2389036 yejE 4493983 yejE Escherichia coli APEC O1 oligopeptide transporter subunit YP_853291.1 2388011 D 405955 CDS YP_853292.1 117624379 4493984 2389038..2390627 1 NC_008563.1 ABC transporter ATP-binding protein 2390627 yejF 4493984 yejF Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_853292.1 2389038 D 405955 CDS YP_853293.1 117624380 4495174 complement(2391309..2392442) 1 NC_008563.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 2392442 bcr 4495174 bcr Escherichia coli APEC O1 bicyclomycin/multidrug efflux system protein YP_853293.1 2391309 R 405955 CDS YP_853294.1 117624381 4495175 complement(2392527..2393222) 1 NC_008563.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2393222 rsuA 4495175 rsuA Escherichia coli APEC O1 16S rRNA pseudouridylate synthase A YP_853294.1 2392527 R 405955 CDS YP_853295.1 117624382 4495176 2393372..2395132 1 NC_008563.1 ATP-dependet helicase 2395132 yejH 4495176 yejH Escherichia coli APEC O1 ATP-dependet helicase YP_853295.1 2393372 D 405955 CDS YP_853297.1 117624384 4495178 complement(2395680..2396687) 1 NC_008563.1 nucleoid-associated protein NdpA 2396687 yejK 4495178 yejK Escherichia coli APEC O1 nucleoid-associated protein NdpA YP_853297.1 2395680 R 405955 CDS YP_853298.1 117624385 4495179 2397116..2398876 1 NC_008563.1 hydrolase, inner membrane 2398876 yejM 4495179 yejM Escherichia coli APEC O1 hydrolase, inner membrane YP_853298.1 2397116 D 405955 CDS YP_853299.1 117624386 4495180 complement(2399129..2399614) 1 NC_008563.1 autotransporter outer membrane protein 2399614 yejO 4495180 yejO Escherichia coli APEC O1 autotransporter outer membrane protein YP_853299.1 2399129 R 405955 CDS YP_853300.1 117624387 4495181 complement(2399957..2400214) 1 NC_008563.1 hypothetical protein 2400214 4495181 APECO1_4366 Escherichia coli APEC O1 hypothetical protein YP_853300.1 2399957 R 405955 CDS YP_853301.1 117624388 4495182 2400216..2400893 1 NC_008563.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2400893 narP 4495182 narP Escherichia coli APEC O1 transcriptional regulator NarP YP_853301.1 2400216 D 405955 CDS YP_853302.1 117624389 4495183 complement(2400928..2401980) 1 NC_008563.1 heme lyase, CcmH subunit 2401980 ccmH 4495183 ccmH Escherichia coli APEC O1 heme lyase, CcmH subunit YP_853302.1 2400928 R 405955 CDS YP_853303.1 117624390 4495184 complement(2401977..2402534) 1 NC_008563.1 periplasmic thioredoxin of cytochrome c-type biogenesis 2402534 ccmG 4495184 ccmG Escherichia coli APEC O1 periplasmic thioredoxin of cytochrome c-type biogenesis YP_853303.1 2401977 R 405955 CDS YP_853304.1 117624391 4495185 complement(2402531..2404474) 1 NC_008563.1 heme lyase, CcmF subunit 2404474 ccmF 4495185 ccmF Escherichia coli APEC O1 heme lyase, CcmF subunit YP_853304.1 2402531 R 405955 CDS YP_853305.1 117624392 4495186 complement(2404471..2404950) 1 NC_008563.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2404950 ccmE 4495186 ccmE Escherichia coli APEC O1 cytochrome c-type biogenesis protein CcmE YP_853305.1 2404471 R 405955 CDS YP_853306.1 117624393 4495187 complement(2405153..2405890) 1 NC_008563.1 heme exporter protein C 2405890 ccmC 4495187 ccmC Escherichia coli APEC O1 heme exporter protein C YP_853306.1 2405153 R 405955 CDS YP_853307.1 117624394 4495188 complement(2405932..2406594) 1 NC_008563.1 heme exporter protein B 2406594 ccmB 4495188 ccmB Escherichia coli APEC O1 heme exporter protein B YP_853307.1 2405932 R 405955 CDS YP_853308.1 117624395 4495189 complement(2406591..2407214) 1 NC_008563.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2407214 ccmA 4495189 ccmA Escherichia coli APEC O1 cytochrome c biogenesis protein CcmA YP_853308.1 2406591 R 405955 CDS YP_853309.1 117624396 4495190 complement(2407227..2407829) 1 NC_008563.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2407829 napC 4495190 napC Escherichia coli APEC O1 cytochrome c-type protein NapC YP_853309.1 2407227 R 405955 CDS YP_853310.1 117624397 4493245 complement(2407839..2408309) 1 NC_008563.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2408309 napB 4493245 napB Escherichia coli APEC O1 citrate reductase cytochrome c-type subunit YP_853310.1 2407839 R 405955 CDS YP_853311.1 117624398 4493246 complement(2408285..2409148) 1 NC_008563.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2409148 napH 4493246 napH Escherichia coli APEC O1 quinol dehydrogenase membrane component YP_853311.1 2408285 R 405955 CDS YP_853312.1 117624399 4493247 complement(2409135..2409830) 1 NC_008563.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2409830 napG 4493247 napG Escherichia coli APEC O1 quinol dehydrogenase periplasmic component YP_853312.1 2409135 R 405955 CDS YP_853313.1 117624400 4493248 complement(2409837..2412323) 1 NC_008563.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2412323 napA 4493248 napA Escherichia coli APEC O1 nitrate reductase catalytic subunit YP_853313.1 2409837 R 405955 CDS YP_853314.1 117624401 4493249 complement(2412320..2412583) 1 NC_008563.1 assembly protein for periplasmic nitrate reductase 2412583 napD 4493249 napD Escherichia coli APEC O1 assembly protein for periplasmic nitrate reductase YP_853314.1 2412320 R 405955 CDS YP_853315.1 117624402 4493250 complement(2412573..2413067) 1 NC_008563.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 2413067 napF 4493250 napF Escherichia coli APEC O1 ferredoxin-type protein YP_853315.1 2412573 R 405955 CDS YP_853316.1 117624403 4493251 complement(2413655..2414113) 1 NC_008563.1 ecotin 2414113 eco 4493251 eco Escherichia coli APEC O1 ecotin YP_853316.1 2413655 R 405955 CDS YP_853317.1 117624404 4493252 complement(2414113..2415759) 1 NC_008563.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2415759 mqo 4493252 mqo Escherichia coli APEC O1 malate:quinone oxidoreductase YP_853317.1 2414113 R 405955 CDS YP_853318.1 117624405 4493253 complement(2415977..2417620) 1 NC_008563.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component 2417620 yojI 4493253 yojI Escherichia coli APEC O1 multidrug transporter membrane protein/ATP-binding component YP_853318.1 2415977 R 405955 CDS YP_853319.1 117624406 4493254 complement(2417696..2418346) 1 NC_008563.1 AlkB repair system protein for alkylated DNA and RNA 2418346 alkB 4493254 alkB Escherichia coli APEC O1 AlkB repair system protein for alkylated DNA and RNA YP_853319.1 2417696 R 405955 CDS YP_853320.1 117624407 4493255 complement(2418346..2419410) 1 NC_008563.1 Ada transcriptional dual regulator / O-6-methylguanine-DNA methyltransferase 2419410 ada 4493255 ada Escherichia coli APEC O1 Ada transcriptional dual regulator / O-6-methylguanine-DNA methyltransferase YP_853320.1 2418346 R 405955 CDS YP_853321.1 117624408 4493256 complement(2419484..2420539) 1 NC_008563.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2420539 yojL 4493256 yojL Escherichia coli APEC O1 thiamine biosynthesis lipoprotein ApbE YP_853321.1 2419484 R 405955 CDS YP_853322.1 117624409 4493257 complement(2420651..2421742) 1 NC_008563.1 OmpC; allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2421742 ompC 4493257 ompC Escherichia coli APEC O1 outer membrane porin protein C YP_853322.1 2420651 R 405955 CDS YP_853323.1 117624410 4493258 2422481..2425153 1 NC_008563.1 phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2425153 yojN 4493258 yojN Escherichia coli APEC O1 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_853323.1 2422481 D 405955 CDS YP_853324.1 117624411 4493259 2425170..2425820 1 NC_008563.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2425820 rcsB 4493259 rcsB Escherichia coli APEC O1 transcriptional regulator RcsB YP_853324.1 2425170 D 405955 CDS YP_853325.1 117624412 4493260 complement(2426020..2428821) 1 NC_008563.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2428821 rcsC 4493260 rcsC Escherichia coli APEC O1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_853325.1 2426020 R 405955 CDS YP_853326.1 117624413 4493261 2429036..2430862 1 NC_008563.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2430862 atoS 4493261 atoS Escherichia coli APEC O1 sensory histidine kinase AtoS YP_853326.1 2429036 D 405955 CDS YP_853327.1 117624414 4492564 2430859..2432244 1 NC_008563.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2432244 atoC 4492564 atoC Escherichia coli APEC O1 acetoacetate metabolism regulatory protein AtoC YP_853327.1 2430859 D 405955 CDS YP_853328.1 117624415 4492567 2432440..2433102 1 NC_008563.1 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2433102 atoD 4492567 atoD Escherichia coli APEC O1 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_853328.1 2432440 D 405955 CDS YP_853329.1 117624416 4492568 2433102..2433752 1 NC_008563.1 acetyl-CoA:acetoacetyl-CoA transferase subunit beta 2433752 atoA 4492568 atoA Escherichia coli APEC O1 acetyl-CoA:acetoacetyl-CoA transferase subunit beta YP_853329.1 2433102 D 405955 CDS YP_853330.1 117624417 4492569 2433749..2435071 1 NC_008563.1 short chain fatty acid transporter 2435071 atoE 4492569 atoE Escherichia coli APEC O1 short chain fatty acid transporter YP_853330.1 2433749 D 405955 CDS YP_853331.1 117624418 4492570 2435102..2435410 1 NC_008563.1 authentic frameshift; acetyl-CoA acetyltransferase 2435410 atoB 4492570 atoB Escherichia coli APEC O1 acetyl-CoA acetyltransferase YP_853331.1 2435102 D 405955 CDS YP_853332.1 117624419 4492571 2435432..2436286 1 NC_008563.1 authentic frameshift; acetyl-CoA acetyltransferase 2436286 atoB 4492571 atoB Escherichia coli APEC O1 acetyl-CoA acetyltransferase YP_853332.1 2435432 D 405955 CDS YP_853333.1 117624420 4492572 complement(2436360..2437136) 1 NC_008563.1 hypothetical protein 2437136 yfaP 4492572 yfaP Escherichia coli APEC O1 hypothetical protein YP_853333.1 2436360 R 405955 CDS YP_853334.1 117624421 4492573 complement(2437141..2438790) 1 NC_008563.1 hypothetical protein 2438790 yfaQ 4492573 yfaQ Escherichia coli APEC O1 hypothetical protein YP_853334.1 2437141 R 405955 CDS YP_853335.1 117624422 4492574 complement(2438791..2443395) 1 NC_008563.1 hypothetical protein 2443395 yfaS 4492574 yfaS Escherichia coli APEC O1 hypothetical protein YP_853335.1 2438791 R 405955 CDS YP_853336.1 117624423 4492575 complement(2443329..2443952) 1 NC_008563.1 hypothetical protein 2443952 yfaT 4492575 yfaT Escherichia coli APEC O1 hypothetical protein YP_853336.1 2443329 R 405955 CDS YP_853337.1 117624424 4492576 complement(2443949..2445637) 1 NC_008563.1 hypothetical protein 2445637 yfaA 4492576 yfaA Escherichia coli APEC O1 hypothetical protein YP_853337.1 2443949 R 405955 CDS YP_853338.1 117624425 4492577 complement(2445786..2448413) 1 NC_008563.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2448413 gyrA 4492577 gyrA Escherichia coli APEC O1 DNA gyrase subunit A YP_853338.1 2445786 R 405955 CDS YP_853339.1 117624426 4492578 2448512..2449282 1 NC_008563.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2449282 ubiG 4492578 ubiG Escherichia coli APEC O1 3-demethylubiquinone-9 3-methyltransferase YP_853339.1 2448512 D 405955 CDS YP_853340.1 117624427 4492579 complement(2449422..2453186) 1 NC_008563.1 adhesin 2453186 4492579 APECO1_4327 Escherichia coli APEC O1 adhesin YP_853340.1 2449422 R 405955 CDS YP_853341.1 117624428 4492580 2453862..2456147 1 NC_008563.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2456147 nrdA 4492580 nrdA Escherichia coli APEC O1 ribonucleotide-diphosphate reductase subunit alpha YP_853341.1 2453862 D 405955 CDS YP_853342.1 117624429 4492581 2456162..2457424 1 NC_008563.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2457424 nrdB 4492581 nrdB Escherichia coli APEC O1 ribonucleotide-diphosphate reductase subunit beta YP_853342.1 2456162 D 405955 CDS YP_853343.1 117624430 4494546 2457424..2457678 1 NC_008563.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2457678 yfaE 4494546 yfaE Escherichia coli APEC O1 2Fe-2S ferredoxin YP_853343.1 2457424 D 405955 CDS YP_853344.1 117624431 4494547 complement(2457732..2458382) 1 NC_008563.1 hypothetical protein 2458382 inaA 4494547 inaA Escherichia coli APEC O1 hypothetical protein YP_853344.1 2457732 R 405955 CDS YP_853345.1 117624432 4494548 complement(2458585..2459661) 1 NC_008563.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2459661 glpQ 4494548 glpQ Escherichia coli APEC O1 glycerophosphodiester phosphodiesterase YP_853345.1 2458585 R 405955 CDS YP_853346.1 117624433 4494549 complement(2459666..2461024) 1 NC_008563.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2461024 glpT 4494549 glpT Escherichia coli APEC O1 sn-glycerol-3-phosphate transporter YP_853346.1 2459666 R 405955 CDS YP_853347.1 117624434 4494550 2461297..2462925 1 NC_008563.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2462925 glpA 4494550 glpA Escherichia coli APEC O1 sn-glycerol-3-phosphate dehydrogenase subunit A YP_853347.1 2461297 D 405955 CDS YP_853348.1 117624435 4494551 2462915..2464174 1 NC_008563.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2464174 glpB 4494551 glpB Escherichia coli APEC O1 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_853348.1 2462915 D 405955 CDS YP_853349.1 117624436 4494552 2464171..2465361 1 NC_008563.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2465361 glpC 4494552 glpC Escherichia coli APEC O1 sn-glycerol-3-phosphate dehydrogenase subunit C YP_853349.1 2464171 D 405955 CDS YP_853350.1 117624437 4494553 2465554..2466513 1 NC_008563.1 hypothetical protein 2466513 yfaD 4494553 yfaD Escherichia coli APEC O1 hypothetical protein YP_853350.1 2465554 D 405955 CDS YP_853351.1 117624438 4494554 complement(2466752..2467555) 1 NC_008563.1 aldolase 2467555 yfaU 4494554 yfaU Escherichia coli APEC O1 aldolase YP_853351.1 2466752 R 405955 CDS YP_853352.1 117624439 4494555 complement(2467573..2468901) 1 NC_008563.1 hypothetical protein 2468901 yfaV 4494555 yfaV Escherichia coli APEC O1 hypothetical protein YP_853352.1 2467573 R 405955 CDS YP_853353.1 117624440 4494556 complement(2468919..2470136) 1 NC_008563.1 hypothetical protein 2470136 yfaW 4494556 yfaW Escherichia coli APEC O1 hypothetical protein YP_853353.1 2468919 R 405955 CDS YP_853354.1 117624441 4494557 complement(2470139..2470921) 1 NC_008563.1 transcriptional regulator YfaX 2470921 yfaX 4494557 yfaX Escherichia coli APEC O1 transcriptional regulator YfaX YP_853354.1 2470139 R 405955 CDS YP_853355.1 117624442 4494558 complement(2471141..2472343) 1 NC_008563.1 competence damage-inducible protein A 2472343 cinA 4494558 cinA Escherichia coli APEC O1 competence damage-inducible protein A YP_853355.1 2471141 R 405955 CDS YP_853356.1 117624443 4494559 complement(2472443..2473000) 1 NC_008563.1 hypothetical protein 2473000 yfaZ 4494559 yfaZ Escherichia coli APEC O1 hypothetical protein YP_853356.1 2472443 R 405955 CDS YP_853357.1 117624444 4494560 2473264..2473689 1 NC_008563.1 Nudix hydrolase YfaO 2473689 yfaO 4494560 yfaO Escherichia coli APEC O1 Nudix hydrolase YfaO YP_853357.1 2473264 D 405955 CDS YP_853358.1 117624445 4494561 complement(2473728..2474330) 1 NC_008563.1 aluminum inducible protein Ais 2474330 ais 4494561 ais Escherichia coli APEC O1 aluminum inducible protein Ais YP_853358.1 2473728 R 405955 CDS YP_853359.1 117624446 4494562 2474605..2475777 1 NC_008563.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2475777 yfbE 4494562 yfbE Escherichia coli APEC O1 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_853359.1 2474605 D 405955 CDS YP_853360.1 117624447 4494563 2475781..2476749 1 NC_008563.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2476749 yfbF 4494563 yfbF Escherichia coli APEC O1 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_853360.1 2475781 D 405955 CDS YP_853361.1 117624448 4494564 2476749..2478731 1 NC_008563.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2478731 yfbG 4494564 yfbG Escherichia coli APEC O1 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_853361.1 2476749 D 405955 CDS YP_853362.1 117624449 4492503 2478728..2479618 1 NC_008563.1 hypothetical protein 2479618 yfbH 4492503 yfbH Escherichia coli APEC O1 hypothetical protein YP_853362.1 2478728 D 405955 CDS YP_853363.1 117624450 4492504 2479618..2481270 1 NC_008563.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2481270 arnT 4492504 arnT Escherichia coli APEC O1 4-amino-4-deoxy-L-arabinose transferase YP_853363.1 2479618 D 405955 CDS YP_853364.2 229775964 4492505 2481602..2481988 1 NC_008563.1 hypothetical protein 2481988 yfbJ 4492505 yfbJ Escherichia coli APEC O1 hypothetical protein YP_853364.2 2481602 D 405955 CDS YP_853365.1 117624452 4492506 complement(2481982..2482278) 1 NC_008563.1 polymyxin B resistance protein PmrD 2482278 pmrD 4492506 pmrD Escherichia coli APEC O1 polymyxin B resistance protein PmrD YP_853365.1 2481982 R 405955 CDS YP_853366.1 117624453 4492507 complement(2482358..2483713) 1 NC_008563.1 O-succinylbenzoic acid--CoA ligase 2483713 menE 4492507 menE Escherichia coli APEC O1 O-succinylbenzoic acid--CoA ligase YP_853366.1 2482358 R 405955 CDS YP_853367.1 117624454 4492508 complement(2483710..2484672) 1 NC_008563.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2484672 menC 4492508 menC Escherichia coli APEC O1 O-succinylbenzoate synthase YP_853367.1 2483710 R 405955 CDS YP_853368.1 117624455 4492509 complement(2484672..2485529) 1 NC_008563.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2485529 menB 4492509 menB Escherichia coli APEC O1 naphthoate synthase YP_853368.1 2484672 R 405955 CDS YP_853369.1 117624456 4492510 complement(2485544..2486302) 1 NC_008563.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 2486302 yfbB 4492510 yfbB Escherichia coli APEC O1 acyl-CoA thioester hydrolase YfbB YP_853369.1 2485544 R 405955 CDS YP_853370.1 117624457 4492511 complement(2486299..2488158) 1 NC_008563.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2488158 menD 4492511 menD Escherichia coli APEC O1 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_853370.1 2486299 R 405955 CDS YP_853371.1 117624458 4492512 complement(2488058..2489353) 1 NC_008563.1 menaquinone-specific isochorismate synthase 2489353 menF 4492512 menF Escherichia coli APEC O1 menaquinone-specific isochorismate synthase YP_853371.1 2488058 R 405955 CDS YP_853372.1 117624459 4492513 complement(2489432..2489737) 1 NC_008563.1 hypothetical protein 2489737 elaB 4492513 elaB Escherichia coli APEC O1 hypothetical protein YP_853372.1 2489432 R 405955 CDS YP_853373.1 117624460 4492514 complement(2489792..2490253) 1 NC_008563.1 hypothetical protein 2490253 elaA 4492514 elaA Escherichia coli APEC O1 hypothetical protein YP_853373.1 2489792 R 405955 CDS YP_853374.1 117624461 4492515 2490318..2491235 1 NC_008563.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2491235 elaC 4492515 elaC Escherichia coli APEC O1 ribonuclease Z YP_853374.1 2490318 D 405955 CDS YP_853375.1 117624462 4492516 complement(2491356..2493098) 1 NC_008563.1 hypothetical protein 2493098 yfbK 4492516 yfbK Escherichia coli APEC O1 hypothetical protein YP_853375.1 2491356 R 405955 CDS YP_853376.1 117624463 4492517 2493236..2494207 1 NC_008563.1 hypothetical protein 2494207 yfbL 4492517 yfbL Escherichia coli APEC O1 hypothetical protein YP_853376.1 2493236 D 405955 CDS YP_853377.1 117624464 4492518 2494310..2494813 1 NC_008563.1 hypothetical protein 2494813 yfbM 4492518 yfbM Escherichia coli APEC O1 hypothetical protein YP_853377.1 2494310 D 405955 CDS YP_853378.1 117624465 4492519 complement(2494880..2496337) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2496337 nuoN 4492519 nuoN Escherichia coli APEC O1 NADH dehydrogenase subunit N YP_853378.1 2494880 R 405955 CDS YP_853379.1 117624466 4492520 complement(2496344..2497873) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2497873 nuoM 4492520 nuoM Escherichia coli APEC O1 NADH dehydrogenase subunit M YP_853379.1 2496344 R 405955 CDS YP_853380.1 117624467 4492521 complement(2498037..2499878) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2499878 nuoL 4492521 nuoL Escherichia coli APEC O1 NADH dehydrogenase subunit L YP_853380.1 2498037 R 405955 CDS YP_853381.1 117624468 4492522 complement(2499875..2500177) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2500177 nuoK 4492522 nuoK Escherichia coli APEC O1 NADH dehydrogenase subunit K YP_853381.1 2499875 R 405955 CDS YP_853382.1 117624469 4495517 complement(2500174..2500728) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2500728 nuoJ 4495517 nuoJ Escherichia coli APEC O1 NADH dehydrogenase subunit J YP_853382.1 2500174 R 405955 CDS YP_853383.1 117624470 4495518 complement(2500740..2501282) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2501282 nuoI 4495518 nuoI Escherichia coli APEC O1 NADH dehydrogenase subunit I YP_853383.1 2500740 R 405955 CDS YP_853384.1 117624471 4495519 complement(2501297..2502274) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2502274 nuoH 4495519 nuoH Escherichia coli APEC O1 NADH dehydrogenase subunit H YP_853384.1 2501297 R 405955 CDS YP_853385.1 117624472 4495520 complement(2502271..2505003) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2505003 nuoG 4495520 nuoG Escherichia coli APEC O1 NADH dehydrogenase subunit G YP_853385.1 2502271 R 405955 CDS YP_853386.1 117624473 4495521 complement(2505050..2506387) 1 NC_008563.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2506387 nuoF 4495521 nuoF Escherichia coli APEC O1 NADH dehydrogenase I subunit F YP_853386.1 2505050 R 405955 CDS YP_853387.1 117624474 4495522 complement(2506384..2506884) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2506884 nuoE 4495522 nuoE Escherichia coli APEC O1 NADH dehydrogenase subunit E YP_853387.1 2506384 R 405955 CDS YP_853388.1 117624475 4495523 complement(2506887..2508689) 1 NC_008563.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2508689 nuoC 4495523 nuoC Escherichia coli APEC O1 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_853388.1 2506887 R 405955 CDS YP_853389.1 117624476 4495524 complement(2508783..2509445) 1 NC_008563.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2509445 nuoB 4495524 nuoB Escherichia coli APEC O1 NADH dehydrogenase subunit B YP_853389.1 2508783 R 405955 CDS YP_853390.1 117624477 4495525 complement(2509461..2509904) 1 NC_008563.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2509904 nuoA 4495525 nuoA Escherichia coli APEC O1 NADH dehydrogenase subunit A YP_853390.1 2509461 R 405955 CDS YP_853391.1 117624478 4495526 complement(2510051..2510320) 1 NC_008563.1 hypothetical protein 2510320 4495526 APECO1_4276 Escherichia coli APEC O1 hypothetical protein YP_853391.1 2510051 R 405955 CDS YP_853392.1 117624479 4495527 complement(2510534..2511472) 1 NC_008563.1 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis protein 2511472 lrhA 4495527 lrhA Escherichia coli APEC O1 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis protein YP_853392.1 2510534 R 405955 CDS YP_853393.1 117624480 4495528 2512392..2513609 1 NC_008563.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2513609 yfbQ 4495528 yfbQ Escherichia coli APEC O1 aminotransferase AlaT YP_853393.1 2512392 D 405955 CDS YP_853394.1 117624481 4495530 2513693..2514292 1 NC_008563.1 hypothetical protein 2514292 yfbR 4495530 yfbR Escherichia coli APEC O1 hypothetical protein YP_853394.1 2513693 D 405955 CDS YP_853395.1 117624482 4495531 complement(2514351..2516183) 1 NC_008563.1 di- and tricarboxylate transporter 2516183 yfbS 4495531 yfbS Escherichia coli APEC O1 di- and tricarboxylate transporter YP_853395.1 2514351 R 405955 CDS YP_853396.1 117624483 4495532 complement(2516270..2516920) 1 NC_008563.1 phosphatase 2516920 yfbT 4495532 yfbT Escherichia coli APEC O1 phosphatase YP_853396.1 2516270 R 405955 CDS YP_853397.1 117624484 4495533 complement(2516931..2517443) 1 NC_008563.1 hypothetical protein 2517443 yfbU 4495533 yfbU Escherichia coli APEC O1 hypothetical protein YP_853397.1 2516931 R 405955 CDS YP_853398.1 117624485 4495534 complement(2517508..2517963) 1 NC_008563.1 hypothetical protein 2517963 yfbV 4495534 yfbV Escherichia coli APEC O1 hypothetical protein YP_853398.1 2517508 R 405955 CDS YP_853399.1 117624486 4495535 2518301..2519503 1 NC_008563.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2519503 ackA 4495535 ackA Escherichia coli APEC O1 acetate kinase YP_853399.1 2518301 D 405955 CDS YP_853401.1 117624488 4493568 2521891..2523432 1 NC_008563.1 hypothetical protein 2523432 yfcC 4493568 yfcC Escherichia coli APEC O1 hypothetical protein YP_853401.1 2521891 D 405955 CDS YP_853402.1 117624489 4493569 complement(2523465..2524007) 1 NC_008563.1 NUDIX hydrolase 2524007 yfcD 4493569 yfcD Escherichia coli APEC O1 NUDIX hydrolase YP_853402.1 2523465 R 405955 CDS YP_853403.1 117624490 4493570 complement(2524065..2524619) 1 NC_008563.1 phosphodiesterase 2524619 yfcE 4493570 yfcE Escherichia coli APEC O1 phosphodiesterase YP_853403.1 2524065 R 405955 CDS YP_853404.1 117624491 4493571 complement(2524672..2525316) 1 NC_008563.1 glutathione S-transferase 2525316 yfcF 4493571 yfcF Escherichia coli APEC O1 glutathione S-transferase YP_853404.1 2524672 R 405955 CDS YP_853405.1 117624492 4493572 2525452..2526099 1 NC_008563.1 glutathione S-transferase 2526099 yfcG 4493572 yfcG Escherichia coli APEC O1 glutathione S-transferase YP_853405.1 2525452 D 405955 CDS YP_853406.1 117624493 4493573 2526156..2526518 1 NC_008563.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2526518 folX 4493573 folX Escherichia coli APEC O1 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_853406.1 2526156 D 405955 CDS YP_853407.1 117624494 4493574 2526539..2527432 1 NC_008563.1 sugar nucleotide epimerase 2527432 yfcH 4493574 yfcH Escherichia coli APEC O1 sugar nucleotide epimerase YP_853407.1 2526539 D 405955 CDS YP_853408.1 117624495 4493575 complement(2527480..2528370) 1 NC_008563.1 hypothetical protein 2528370 yfcI 4493575 yfcI Escherichia coli APEC O1 hypothetical protein YP_853408.1 2527480 R 405955 CDS YP_853409.1 117624496 4493576 complement(2528566..2529339) 1 NC_008563.1 histidine/lysine/arginine/ornithine transporter subunit 2529339 hisP 4493576 hisP Escherichia coli APEC O1 histidine/lysine/arginine/ornithine transporter subunit YP_853409.1 2528566 R 405955 CDS YP_853410.1 117624497 4493577 complement(2529347..2530063) 1 NC_008563.1 histidine/lysine/arginine/ornithine transporter subunit 2530063 hisM 4493577 hisM Escherichia coli APEC O1 histidine/lysine/arginine/ornithine transporter subunit YP_853410.1 2529347 R 405955 CDS YP_853411.1 117624498 4493578 complement(2530060..2530746) 1 NC_008563.1 histidine transport system permease HisQ 2530746 hisQ 4493578 hisQ Escherichia coli APEC O1 histidine transport system permease HisQ YP_853411.1 2530060 R 405955 CDS YP_853412.1 117624499 4493579 complement(2530836..2531618) 1 NC_008563.1 histidine/lysine/arginine/ornithine transporter subunit 2531618 hisJ 4493579 hisJ Escherichia coli APEC O1 histidine/lysine/arginine/ornithine transporter subunit YP_853412.1 2530836 R 405955 CDS YP_853413.1 117624500 4493580 complement(2531839..2532621) 1 NC_008563.1 lysine/arginine/ornithine transporter subunit 2532621 argT 4493580 argT Escherichia coli APEC O1 lysine/arginine/ornithine transporter subunit YP_853413.1 2531839 R 405955 CDS YP_853414.1 117624501 4493581 complement(2532887..2533456) 1 NC_008563.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2533456 ubiX 4493581 ubiX Escherichia coli APEC O1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_853414.1 2532887 R 405955 CDS YP_853415.1 117624502 4493582 complement(2533551..2535068) 1 NC_008563.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2535068 purF 4493582 purF Escherichia coli APEC O1 amidophosphoribosyltransferase YP_853415.1 2533551 R 405955 CDS YP_853416.1 117624503 4493583 complement(2535105..2535593) 1 NC_008563.1 membrane protein required for colicin V production; colicin V production protein 2535593 cvpA 4493583 cvpA Escherichia coli APEC O1 colicin V production protein YP_853416.1 2535105 R 405955 CDS YP_853417.1 117624504 4493584 complement(2536125..2536787) 1 NC_008563.1 hypothetical protein 2536787 dedD 4493584 dedD Escherichia coli APEC O1 hypothetical protein YP_853417.1 2536125 R 405955 CDS YP_853418.1 117624505 4493585 complement(2536777..2538045) 1 NC_008563.1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2538045 folC 4493585 folC Escherichia coli APEC O1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_853418.1 2536777 R 405955 CDS YP_853419.2 162317573 4493586 complement(2538115..2539029) 1 NC_008563.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2539029 accD 4493586 accD Escherichia coli APEC O1 acetyl-CoA carboxylase subunit beta YP_853419.2 2538115 R 405955 CDS YP_853420.1 117624507 4495788 complement(2539185..2539844) 1 NC_008563.1 hypothetical protein 2539844 4495788 APECO1_4247 Escherichia coli APEC O1 hypothetical protein YP_853420.1 2539185 R 405955 CDS YP_853421.1 117624508 4495789 complement(2539927..2540739) 1 NC_008563.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2540739 truA 4495789 truA Escherichia coli APEC O1 tRNA pseudouridine synthase A YP_853421.1 2539927 R 405955 CDS YP_853422.1 117624509 4495790 complement(2540739..2541752) 1 NC_008563.1 semialdehyde dehydrogenase 2541752 usg 4495790 usg Escherichia coli APEC O1 semialdehyde dehydrogenase YP_853422.1 2540739 R 405955 CDS YP_853423.1 117624510 4495791 complement(2541818..2542954) 1 NC_008563.1 erythronate-4-phosphate dehydrogenase 2542954 pdxB 4495791 pdxB Escherichia coli APEC O1 erythronate-4-phosphate dehydrogenase YP_853423.1 2541818 R 405955 CDS YP_853424.1 117624511 4495792 2543053..2544048 1 NC_008563.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2544048 flk 4495792 flk Escherichia coli APEC O1 flagella biosynthesis regulator YP_853424.1 2543053 D 405955 CDS YP_853425.1 117624512 4495793 complement(2544045..2545223) 1 NC_008563.1 hypothetical protein 2545223 yfcJ 4495793 yfcJ Escherichia coli APEC O1 hypothetical protein YP_853425.1 2544045 R 405955 CDS YP_853426.1 117624513 4495794 complement(2545488..2546708) 1 NC_008563.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2546708 fabB 4495794 fabB Escherichia coli APEC O1 3-oxoacyl-ACP synthase YP_853426.1 2545488 R 405955 CDS YP_853427.1 117624514 4495795 2546867..2548873 1 NC_008563.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2548873 mnmC 4495795 mnmC Escherichia coli APEC O1 5-methylaminomethyl-2-thiouridine methyltransferase YP_853427.1 2546867 D 405955 CDS YP_853428.1 117624515 4495796 complement(2548994..2549272) 1 NC_008563.1 hypothetical protein 2549272 yfcL 4495796 yfcL Escherichia coli APEC O1 hypothetical protein YP_853428.1 2548994 R 405955 CDS YP_853429.1 117624516 4495797 complement(2549306..2549854) 1 NC_008563.1 hypothetical protein 2549854 yfcM 4495797 yfcM Escherichia coli APEC O1 hypothetical protein YP_853429.1 2549306 R 405955 CDS YP_853430.1 117624517 4495798 complement(2549854..2550663) 1 NC_008563.1 hypothetical protein 2550663 yfcA 4495798 yfcA Escherichia coli APEC O1 hypothetical protein YP_853430.1 2549854 R 405955 CDS YP_853431.1 117624518 4495799 complement(2550663..2551487) 1 NC_008563.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2551487 mepA 4495799 mepA Escherichia coli APEC O1 penicillin-insensitive murein endopeptidase YP_853431.1 2550663 R 405955 CDS YP_853432.1 117624519 4495800 complement(2551491..2552576) 1 NC_008563.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2552576 aroC 4495800 aroC Escherichia coli APEC O1 chorismate synthase YP_853432.1 2551491 R 405955 CDS YP_853433.1 117624520 4495801 complement(2552611..2553876) 1 NC_008563.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2553876 prmB 4495801 prmB Escherichia coli APEC O1 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_853433.1 2552611 R 405955 CDS YP_853434.1 117624521 4495802 complement(2554580..2555422) 1 NC_008563.1 fimbrial adhesin YfcO 2555422 yfcO 4495802 yfcO Escherichia coli APEC O1 fimbrial adhesin YfcO YP_853434.1 2554580 R 405955 CDS YP_853435.1 117624522 4495803 complement(2555424..2555951) 1 NC_008563.1 Yfc fimbriae subunit YfcP 2555951 yfcP 4495803 yfcP Escherichia coli APEC O1 Yfc fimbriae subunit YfcP YP_853435.1 2555424 R 405955 CDS YP_853436.1 117624523 4495804 complement(2555948..2556427) 1 NC_008563.1 Yfc fimbriae subunit YfcQ 2556427 yfcQ 4495804 yfcQ Escherichia coli APEC O1 Yfc fimbriae subunit YfcQ YP_853436.1 2555948 R 405955 CDS YP_853437.1 117624524 4495805 complement(2556424..2556969) 1 NC_008563.1 hypothetical protein 2556969 yfcR 4495805 yfcR Escherichia coli APEC O1 hypothetical protein YP_853437.1 2556424 R 405955 CDS YP_853438.1 117624525 4495806 complement(2556944..2557696) 1 NC_008563.1 periplasmic chaperone YfcS 2557696 yfcS 4495806 yfcS Escherichia coli APEC O1 periplasmic chaperone YfcS YP_853438.1 2556944 R 405955 CDS YP_853439.1 117624526 4495593 complement(2557716..2560370) 1 NC_008563.1 pilus assembly protein; outer membrane usher YfcU 2560370 yfcU 4495593 yfcU Escherichia coli APEC O1 outer membrane usher YfcU YP_853439.1 2557716 R 405955 CDS YP_853440.1 117624527 4495594 complement(2560238..2560987) 1 NC_008563.1 Yfc fimbriae subunit YfcV 2560987 yfcV 4495594 yfcV Escherichia coli APEC O1 Yfc fimbriae subunit YfcV YP_853440.1 2560238 R 405955 CDS YP_853441.1 117624528 4495595 complement(2561553..2562038) 1 NC_008563.1 phosphohistidine phosphatase 2562038 sixA 4495595 sixA Escherichia coli APEC O1 phosphohistidine phosphatase YP_853441.1 2561553 R 405955 CDS YP_853442.1 117624529 4495596 complement(2562241..2564385) 1 NC_008563.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2564385 fadJ 4495596 fadJ Escherichia coli APEC O1 multifunctional fatty acid oxidation complex subunit alpha YP_853442.1 2562241 R 405955 CDS YP_853443.1 117624530 4495597 complement(2564385..2565695) 1 NC_008563.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2565695 fadI 4495597 fadI Escherichia coli APEC O1 3-ketoacyl-CoA thiolase YP_853443.1 2564385 R 405955 CDS YP_853444.1 117624531 4495598 complement(2565876..2566184) 1 NC_008563.1 hypothetical protein 2566184 yfcZ 4495598 yfcZ Escherichia coli APEC O1 hypothetical protein YP_853444.1 2565876 R 405955 CDS YP_853445.1 117624532 4495599 complement(2566245..2566496) 1 NC_008563.1 hypothetical protein 2566496 4495599 APECO1_4222 Escherichia coli APEC O1 hypothetical protein YP_853445.1 2566245 R 405955 CDS YP_853446.1 117624533 4495600 2566526..2567872 1 NC_008563.1 long-chain fatty acid outer membrane transporter 2567872 fadL 4495600 fadL Escherichia coli APEC O1 long-chain fatty acid outer membrane transporter YP_853446.1 2566526 D 405955 CDS YP_853447.1 117624534 4495601 complement(2567930..2568685) 1 NC_008563.1 lipoprotein VacJ 2568685 vacJ 4495601 vacJ Escherichia coli APEC O1 lipoprotein VacJ YP_853447.1 2567930 R 405955 CDS YP_853448.1 117624535 4495602 2568979..2569911 1 NC_008563.1 transporter 2569911 yfdC 4495602 yfdC Escherichia coli APEC O1 transporter YP_853448.1 2568979 D 405955 CDS YP_853449.1 117624536 4495603 2570223..2571380 1 NC_008563.1 phage integrase 2571380 4495603 APECO1_4218 Escherichia coli APEC O1 phage integrase YP_853449.1 2570223 D 405955 CDS YP_853450.1 117624537 4495604 complement(2571620..2572543) 1 NC_008563.1 capsule O-acetyl transferase 2572543 4495604 APECO1_4217 Escherichia coli APEC O1 capsule O-acetyl transferase YP_853450.1 2571620 R 405955 CDS YP_853451.1 117624538 4495605 complement(2572697..2575642) 1 NC_008563.1 phage-associated; endo-alpha-sialidase 2575642 sia 4495605 sia Escherichia coli APEC O1 endo-alpha-sialidase YP_853451.1 2572697 R 405955 CDS YP_853452.1 117624539 4495606 complement(2575743..2576645) 1 NC_008563.1 phage-associated; antirepressor protein 2576645 4495606 APECO1_4215 Escherichia coli APEC O1 antirepressor protein YP_853452.1 2575743 R 405955 CDS YP_853453.1 117624540 4495607 2577393..2577929 1 NC_008563.1 protease; hypothetical protein 2577929 4495607 APECO1_4214 Escherichia coli APEC O1 hypothetical protein YP_853453.1 2577393 D 405955 CDS YP_853454.1 117624541 4495608 complement(2577978..2578427) 1 NC_008563.1 hypothetical protein 2578427 4495608 APECO1_4213 Escherichia coli APEC O1 hypothetical protein YP_853454.1 2577978 R 405955 CDS YP_853455.1 117624542 4495609 complement(2578436..2579002) 1 NC_008563.1 hypothetical protein 2579002 4495609 APECO1_4212 Escherichia coli APEC O1 hypothetical protein YP_853455.1 2578436 R 405955 CDS YP_853456.1 117624543 4495610 2579199..2579528 1 NC_008563.1 hypothetical protein 2579528 4495610 APECO1_42112 Escherichia coli APEC O1 hypothetical protein YP_853456.1 2579199 D 405955 CDS YP_853457.1 117624544 4495611 complement(2579546..2581561) 1 NC_008563.1 hypothetical protein 2581561 4495611 APECO1_4211 Escherichia coli APEC O1 hypothetical protein YP_853457.1 2579546 R 405955 CDS YP_853458.1 117624545 4495612 complement(2581558..2583009) 1 NC_008563.1 phage injection protein 2583009 4495612 APECO1_4210 Escherichia coli APEC O1 phage injection protein YP_853458.1 2581558 R 405955 CDS YP_853459.1 117624546 4494271 complement(2583020..2583712) 1 NC_008563.1 phage-associated; DNA transfer protein 2583712 4494271 APECO1_4209 Escherichia coli APEC O1 DNA transfer protein YP_853459.1 2583020 R 405955 CDS YP_853460.1 117624547 4494272 complement(2583715..2584170) 1 NC_008563.1 phage-associated; head assembly protein 2584170 4494272 APECO1_4208 Escherichia coli APEC O1 head assembly protein YP_853460.1 2583715 R 405955 CDS YP_853461.1 117624548 4494273 complement(2584170..2584871) 1 NC_008563.1 phage-associated; DNA stabilization protein 2584871 4494273 APECO1_4207 Escherichia coli APEC O1 DNA stabilization protein YP_853461.1 2584170 R 405955 CDS YP_853462.1 117624549 4494274 complement(2584871..2586289) 1 NC_008563.1 phage-associated; DNA stabilization protein 2586289 4494274 APECO1_4206 Escherichia coli APEC O1 DNA stabilization protein YP_853462.1 2584871 R 405955 CDS YP_853463.1 117624550 4494275 complement(2586299..2586760) 1 NC_008563.1 DNA stabilization protein 2586760 4494275 APECO1_4205 Escherichia coli APEC O1 DNA stabilization protein YP_853463.1 2586299 R 405955 CDS YP_853464.1 117624551 4494276 complement(2586971..2588224) 1 NC_008563.1 phage coat protein; hypothetical protein 2588224 4494276 APECO1_4204 Escherichia coli APEC O1 hypothetical protein YP_853464.1 2586971 R 405955 CDS YP_853465.1 117624552 4494277 complement(2588243..2589136) 1 NC_008563.1 phage scaffold protein 2589136 4494277 APECO1_4203 Escherichia coli APEC O1 phage scaffold protein YP_853465.1 2588243 R 405955 CDS YP_853466.1 117624553 4494278 complement(2589227..2591425) 1 NC_008563.1 phage portal protein 2591425 4494278 APECO1_4202 Escherichia coli APEC O1 phage portal protein YP_853466.1 2589227 R 405955 CDS YP_853467.1 117624554 4494279 complement(2591427..2592842) 1 NC_008563.1 phage terminase large subunit 2592842 4494279 APECO1_4201 Escherichia coli APEC O1 phage terminase large subunit YP_853467.1 2591427 R 405955 CDS YP_853468.1 117624555 4494280 complement(2592839..2593279) 1 NC_008563.1 phage-associated; hypothetical protein 2593279 4494280 APECO1_4200 Escherichia coli APEC O1 hypothetical protein YP_853468.1 2592839 R 405955 CDS YP_853469.1 117624556 4494281 complement(2593282..2593524) 1 NC_008563.1 phage-associated; hypothetical protein 2593524 4494281 APECO1_4199 Escherichia coli APEC O1 hypothetical protein YP_853469.1 2593282 R 405955 CDS YP_853470.1 117624557 4494282 complement(2593752..2594363) 1 NC_008563.1 phage-associated; hypothetical protein 2594363 4494282 APECO1_4198 Escherichia coli APEC O1 hypothetical protein YP_853470.1 2593752 R 405955 CDS YP_853471.1 117624558 4494283 complement(2594640..2595077) 1 NC_008563.1 phage-associated; hypothetical protein 2595077 4494283 APECO1_4197 Escherichia coli APEC O1 hypothetical protein YP_853471.1 2594640 R 405955 CDS YP_853472.1 117624559 4494284 complement(2595074..2595550) 1 NC_008563.1 phage-associated; endolysin 2595550 4494284 APECO1_4196 Escherichia coli APEC O1 endolysin YP_853472.1 2595074 R 405955 CDS YP_853473.1 117624560 4494285 complement(2595534..2595857) 1 NC_008563.1 cell lysis protein; holin 2595857 4494285 APECO1_4195 Escherichia coli APEC O1 holin YP_853473.1 2595534 R 405955 CDS YP_853474.1 117624561 4494286 complement(2596454..2596972) 1 NC_008563.1 phage-associated; antitermination protein 2596972 4494286 APECO1_4194 Escherichia coli APEC O1 antitermination protein YP_853474.1 2596454 R 405955 CDS YP_853475.1 117624562 4494287 complement(2597154..2597516) 1 NC_008563.1 Holliday junction resolvase 2597516 4494287 APECO1_4193 Escherichia coli APEC O1 Holliday junction resolvase YP_853475.1 2597154 R 405955 CDS YP_853476.1 117624563 4494288 complement(2597513..2597803) 1 NC_008563.1 phage-associated; hypothetical protein 2597803 4494288 APECO1_4192 Escherichia coli APEC O1 hypothetical protein YP_853476.1 2597513 R 405955 CDS YP_853477.1 117624564 4494289 complement(2597803..2598525) 1 NC_008563.1 phage-associated; DNA-binding protein Roi 2598525 roi 4494289 roi Escherichia coli APEC O1 DNA-binding protein Roi YP_853477.1 2597803 R 405955 CDS YP_853478.1 117624565 4493527 complement(2598687..2599112) 1 NC_008563.1 hypothetical protein 2599112 4493527 APECO1_4190 Escherichia coli APEC O1 hypothetical protein YP_853478.1 2598687 R 405955 CDS YP_853479.1 117624566 4493528 complement(2599282..2599542) 1 NC_008563.1 phage-associated; hypothetical protein 2599542 4493528 APECO1_4189 Escherichia coli APEC O1 hypothetical protein YP_853479.1 2599282 R 405955 CDS YP_853480.1 117624567 4493529 complement(2599892..2600206) 1 NC_008563.1 phage-associated; hypothetical protein 2600206 4493529 APECO1_4188 Escherichia coli APEC O1 hypothetical protein YP_853480.1 2599892 R 405955 CDS YP_853481.1 117624568 4493530 complement(2600601..2601977) 1 NC_008563.1 phage-associated; replicative DNA helicase 2601977 4493530 APECO1_4187 Escherichia coli APEC O1 replicative DNA helicase YP_853481.1 2600601 R 405955 CDS YP_853482.1 117624569 4493531 complement(2601974..2602921) 1 NC_008563.1 phage replication protein 2602921 4493531 APECO1_4186 Escherichia coli APEC O1 phage replication protein YP_853482.1 2601974 R 405955 CDS YP_853483.1 117624570 4493532 complement(2602924..2603196) 1 NC_008563.1 hypothetical protein 2603196 4493532 APECO1_4185 Escherichia coli APEC O1 hypothetical protein YP_853483.1 2602924 R 405955 CDS YP_853484.1 117624571 4493533 complement(2603219..2603599) 1 NC_008563.1 phage-associated; hypothetical protein 2603599 4493533 APECO1_4184 Escherichia coli APEC O1 hypothetical protein YP_853484.1 2603219 R 405955 CDS YP_853485.1 117624572 4493534 2603887..2604537 1 NC_008563.1 phage repressor protein 2604537 4493534 APECO1_4183 Escherichia coli APEC O1 phage repressor protein YP_853485.1 2603887 D 405955 CDS YP_853486.1 117624573 4493535 complement(2604659..2604955) 1 NC_008563.1 hypothetical protein 2604955 4493535 APECO1_4182 Escherichia coli APEC O1 hypothetical protein YP_853486.1 2604659 R 405955 CDS YP_853487.1 117624574 4493536 2605060..2605359 1 NC_008563.1 phage-associated; transcription antitermination protein 2605359 4493536 APECO1_4180 Escherichia coli APEC O1 transcription antitermination protein YP_853487.1 2605060 D 405955 CDS YP_853488.1 117624575 4493537 2605368..2605838 1 NC_008563.1 phage-associated; hypothetical protein 2605838 4493537 APECO1_4179 Escherichia coli APEC O1 hypothetical protein YP_853488.1 2605368 D 405955 CDS YP_853489.1 117624576 4493538 2606460..2607065 1 NC_008563.1 phage-associated; hypothetical protein 2607065 4493538 APECO1_4178 Escherichia coli APEC O1 hypothetical protein YP_853489.1 2606460 D 405955 CDS YP_853490.1 117624577 4493539 2607065..2607448 1 NC_008563.1 phage-associated; hypothetical protein 2607448 4493539 APECO1_4177 Escherichia coli APEC O1 hypothetical protein YP_853490.1 2607065 D 405955 CDS YP_853491.1 117624578 4493540 2607472..2607768 1 NC_008563.1 hypothetical protein 2607768 4493540 APECO1_4176 Escherichia coli APEC O1 hypothetical protein YP_853491.1 2607472 D 405955 CDS YP_853492.1 117624579 4493541 complement(2607817..2608503) 1 NC_008563.1 hypothetical protein 2608503 4493541 APECO1_4175 Escherichia coli APEC O1 hypothetical protein YP_853492.1 2607817 R 405955 CDS YP_853493.1 117624580 4493542 2608679..2609251 1 NC_008563.1 hypothetical protein 2609251 4493542 APECO1_4174 Escherichia coli APEC O1 hypothetical protein YP_853493.1 2608679 D 405955 CDS YP_853494.1 117624581 4493543 complement(2609618..2609953) 1 NC_008563.1 hypothetical protein 2609953 4493543 APECO1_4173 Escherichia coli APEC O1 hypothetical protein YP_853494.1 2609618 R 405955 CDS YP_853495.1 117624582 4493544 complement(2610499..2611434) 1 NC_008563.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 2611434 dsdC 4493544 dsdC Escherichia coli APEC O1 DNA-binding transcriptional regulator DsdC YP_853495.1 2610499 R 405955 CDS YP_853496.1 117624583 4493545 2611652..2612989 1 NC_008563.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2612989 dsdX 4493545 dsdX Escherichia coli APEC O1 permease DsdX YP_853496.1 2611652 D 405955 CDS YP_853497.1 117624584 4493546 2613007..2614335 1 NC_008563.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2614335 dsdA 4493546 dsdA Escherichia coli APEC O1 D-serine dehydratase YP_853497.1 2613007 D 405955 CDS YP_853498.1 117624585 4492484 complement(2614443..2615981) 1 NC_008563.1 multidrug resistance protein Y 2615981 emrY 4492484 emrY Escherichia coli APEC O1 multidrug resistance protein Y YP_853498.1 2614443 R 405955 CDS YP_853499.1 117624586 4492485 complement(2615981..2617036) 1 NC_008563.1 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein 2617036 emrK 4492485 emrK Escherichia coli APEC O1 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein YP_853499.1 2615981 R 405955 CDS YP_853500.1 117624587 4492486 2617560..2618174 1 NC_008563.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; EvgA family transcriptional regulator 2618174 evgA 4492486 evgA Escherichia coli APEC O1 EvgA family transcriptional regulator YP_853500.1 2617560 D 405955 CDS YP_853501.1 117624588 4492487 2618179..2621772 1 NC_008563.1 EvgA family transcriptional regulator 2621772 evgS 4492487 evgS Escherichia coli APEC O1 EvgA family transcriptional regulator YP_853501.1 2618179 D 405955 CDS YP_853502.1 117624589 4492488 complement(2621828..2622973) 1 NC_008563.1 hypothetical protein 2622973 yfdE 4492488 yfdE Escherichia coli APEC O1 hypothetical protein YP_853502.1 2621828 R 405955 CDS YP_853503.1 117624590 4492489 complement(2623047..2623991) 1 NC_008563.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 2623991 yfdV 4492489 yfdV Escherichia coli APEC O1 transporter YfdV YP_853503.1 2623047 R 405955 CDS YP_853504.1 117624591 4492490 complement(2624061..2625755) 1 NC_008563.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 2625755 4492490 APECO1_4163 Escherichia coli APEC O1 oxalyl-CoA decarboxylase YP_853504.1 2624061 R 405955 CDS YP_853505.1 117624592 4492491 complement(2625809..2627059) 1 NC_008563.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2627059 yfdW 4492491 yfdW Escherichia coli APEC O1 formyl-coenzyme A transferase YP_853505.1 2625809 R 405955 CDS YP_853506.1 117624593 4492492 complement(2627571..2628206) 1 NC_008563.1 hypothetical protein 2628206 yfdX 4492492 yfdX Escherichia coli APEC O1 hypothetical protein YP_853506.1 2627571 R 405955 CDS YP_853507.1 117624594 4492493 2628502..2628777 1 NC_008563.1 lipoprotein involved in colanic acid biosynthesis 2628777 ypdI 4492493 ypdI Escherichia coli APEC O1 lipoprotein involved in colanic acid biosynthesis YP_853507.1 2628502 D 405955 CDS YP_853508.1 117624595 4492494 2629449..2630369 1 NC_008563.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2630369 ddg 4492494 ddg Escherichia coli APEC O1 lipid A biosynthesis palmitoleoyl acyltransferase YP_853508.1 2629449 D 405955 CDS YP_853509.1 117624596 4492495 complement(2630861..2632099) 1 NC_008563.1 aminotransferase 2632099 4492495 APECO1_4158 Escherichia coli APEC O1 aminotransferase YP_853509.1 2630861 R 405955 CDS YP_853510.1 117624597 4492496 2632494..2634173 1 NC_008563.1 YpdA, sensory kinase in two-component system with YpdB 2634173 ypdA 4492496 ypdA Escherichia coli APEC O1 YpdA, sensory kinase in two-component system with YpdB YP_853510.1 2632494 D 405955 CDS YP_853511.1 117624598 4492497 2634263..2634925 1 NC_008563.1 YpdB, response regulator in two-component system with YpdA 2634925 ypdB 4492497 ypdB Escherichia coli APEC O1 YpdB, response regulator in two-component system with YpdA YP_853511.1 2634263 D 405955 CDS YP_853512.1 117624599 4492498 2634938..2635795 1 NC_008563.1 DNA-binding protein 2635795 ypdC 4492498 ypdC Escherichia coli APEC O1 DNA-binding protein YP_853512.1 2634938 D 405955 CDS YP_853513.1 117624600 4492499 complement(2635798..2638293) 1 NC_008563.1 phosphoenolpyruvate-protein phosphotransferase YpdD 2638293 ypdD 4492499 ypdD Escherichia coli APEC O1 phosphoenolpyruvate-protein phosphotransferase YpdD YP_853513.1 2635798 R 405955 CDS YP_853514.1 117624601 4492500 complement(2638318..2639355) 1 NC_008563.1 peptidase; metalloprotein; exoaminopeptidase 2639355 ypdE 4492500 ypdE Escherichia coli APEC O1 exoaminopeptidase YP_853514.1 2638318 R 405955 CDS YP_853515.1 117624602 4492501 complement(2639355..2640440) 1 NC_008563.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2640440 ypdF 4492501 ypdF Escherichia coli APEC O1 aminopeptidase YP_853515.1 2639355 R 405955 CDS YP_853516.1 117624603 4492502 complement(2640456..2641703) 1 NC_008563.1 PTS system trannsporter subunit IIC 2641703 ypdG 4492502 ypdG Escherichia coli APEC O1 PTS system trannsporter subunit IIC YP_853516.1 2640456 R 405955 CDS YP_853517.1 117624604 4491676 complement(2641725..2642051) 1 NC_008563.1 PTS system IIB component YpdH 2642051 ypdH 4491676 ypdH Escherichia coli APEC O1 PTS system IIB component YpdH YP_853517.1 2641725 R 405955 CDS YP_853518.1 117624605 4491677 complement(2642270..2643235) 1 NC_008563.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2643235 glk 4491677 glk Escherichia coli APEC O1 glucokinase YP_853518.1 2642270 R 405955 CDS YP_853519.1 117624606 4491678 2643439..2644695 1 NC_008563.1 hypothetical protein 2644695 yfeO 4491678 yfeO Escherichia coli APEC O1 hypothetical protein YP_853519.1 2643439 D 405955 CDS YP_853520.1 117624607 4491679 2644810..2645136 1 NC_008563.1 hypothetical protein 2645136 ypeC 4491679 ypeC Escherichia coli APEC O1 hypothetical protein YP_853520.1 2644810 D 405955 CDS YP_853521.1 117624608 4491680 complement(2645277..2646515) 1 NC_008563.1 manganese transport protein MntH 2646515 mntH 4491680 mntH Escherichia coli APEC O1 manganese transport protein MntH YP_853521.1 2645277 R 405955 CDS YP_853522.1 117624609 4491681 2646851..2648053 1 NC_008563.1 permease of transport system for 3 nucleosides 2648053 nupC 4491681 nupC Escherichia coli APEC O1 permease of transport system for 3 nucleosides YP_853522.1 2646851 D 405955 CDS YP_853523.1 117624610 4491682 complement(2648103..2650352) 1 NC_008563.1 ELA domain; outer membrane protein 2650352 yfdA 4491682 yfdA Escherichia coli APEC O1 outer membrane protein YP_853523.1 2648103 R 405955 CDS YP_853524.1 117624611 4491683 2650910..2651269 1 NC_008563.1 outer membrane protein 2651269 yfdC 4491683 yfdC Escherichia coli APEC O1 outer membrane protein YP_853524.1 2650910 D 405955 CDS YP_853525.1 117624612 4491684 2651271..2651663 1 NC_008563.1 DNA-binding transcriptional regulator 2651663 yfeD 4491684 yfeD Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_853525.1 2651271 D 405955 CDS YP_853526.1 117624613 4491685 complement(2651714..2653129) 1 NC_008563.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2653129 gltX 4491685 gltX Escherichia coli APEC O1 glutamyl-tRNA synthetase YP_853526.1 2651714 R 405955 CDS YP_853527.1 117624614 4491686 complement(2653896..2654795) 1 NC_008563.1 DNA-binding transcriptional activator XapR 2654795 xapR 4491686 xapR Escherichia coli APEC O1 DNA-binding transcriptional activator XapR YP_853527.1 2653896 R 405955 CDS YP_853528.1 117624615 4491687 complement(2655032..2656288) 1 NC_008563.1 xanthosine transporter 2656288 xapB 4491687 xapB Escherichia coli APEC O1 xanthosine transporter YP_853528.1 2655032 R 405955 CDS YP_853529.1 117624616 4491688 complement(2656349..2657182) 1 NC_008563.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2657182 xapA 4491688 xapA Escherichia coli APEC O1 purine nucleoside phosphorylase YP_853529.1 2656349 R 405955 CDS YP_853530.1 117624617 4491689 2657431..2658195 1 NC_008563.1 sugar hydrolase; hypothetical protein 2658195 yfeN 4491689 yfeN Escherichia coli APEC O1 hypothetical protein YP_853530.1 2657431 D 405955 CDS YP_853531.1 117624618 4491690 2659250..2660248 1 NC_008563.1 cytochrome oxidase 2660248 yfeH 4491690 yfeH Escherichia coli APEC O1 cytochrome oxidase YP_853531.1 2659250 D 405955 CDS YP_853532.1 117624619 4491691 complement(2660465..2662480) 1 NC_008563.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2662480 ligA 4491691 ligA Escherichia coli APEC O1 NAD-dependent DNA ligase LigA YP_853532.1 2660465 R 405955 CDS YP_853533.1 117624620 4491692 complement(2662551..2663549) 1 NC_008563.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2663549 zipA 4491692 zipA Escherichia coli APEC O1 cell division protein ZipA YP_853533.1 2662551 R 405955 CDS YP_853534.1 117624621 4491693 2663779..2664540 1 NC_008563.1 role in sulfur assimilation; sulfate transport protein CysZ 2664540 cysZ 4491693 cysZ Escherichia coli APEC O1 sulfate transport protein CysZ YP_853534.1 2663779 D 405955 CDS YP_853535.1 117624622 4491694 2664725..2665696 1 NC_008563.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2665696 cysK 4491694 cysK Escherichia coli APEC O1 cysteine synthase A YP_853535.1 2664725 D 405955 CDS YP_853536.1 117624623 4491695 complement(2666014..2666307) 1 NC_008563.1 hypothetical protein 2666307 4491695 APECO1_4130 Escherichia coli APEC O1 hypothetical protein YP_853536.1 2666014 R 405955 CDS YP_853537.1 117624624 4495731 2666382..2668109 1 NC_008563.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2668109 ptsI 4495731 ptsI Escherichia coli APEC O1 phosphoenolpyruvate-protein phosphotransferase YP_853537.1 2666382 D 405955 CDS YP_853538.1 117624625 4495732 2668150..2668659 1 NC_008563.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2668659 crr 4495732 crr Escherichia coli APEC O1 PTS system glucose-specific transporter YP_853538.1 2668150 D 405955 CDS YP_853539.1 117624626 4495733 complement(2668702..2669553) 1 NC_008563.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2669553 pdxK 4495733 pdxK Escherichia coli APEC O1 pyridoxal kinase YP_853539.1 2668702 R 405955 CDS YP_853540.1 117624627 4495734 2669694..2670026 1 NC_008563.1 hypothetical protein 2670026 yfeK 4495734 yfeK Escherichia coli APEC O1 hypothetical protein YP_853540.1 2669694 D 405955 CDS YP_853541.1 117624628 4495735 complement(2670029..2670886) 1 NC_008563.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2670886 cysM 4495735 cysM Escherichia coli APEC O1 cysteine synthase B YP_853541.1 2670029 R 405955 CDS YP_853542.1 117624629 4495736 complement(2671075..2672172) 1 NC_008563.1 sulfate/thiosulfate transporter subunit 2672172 cysA 4495736 cysA Escherichia coli APEC O1 sulfate/thiosulfate transporter subunit YP_853542.1 2671075 R 405955 CDS YP_853543.1 117624630 4495737 complement(2672162..2673037) 1 NC_008563.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2673037 cysW 4495737 cysW Escherichia coli APEC O1 sulfate/thiosulfate transporter permease subunit YP_853543.1 2672162 R 405955 CDS YP_853544.1 117624631 4495738 complement(2673037..2673870) 1 NC_008563.1 sulfate/thiosulfate transporter subunit 2673870 cysT 4495738 cysT Escherichia coli APEC O1 sulfate/thiosulfate transporter subunit YP_853544.1 2673037 R 405955 CDS YP_853545.1 117624632 4495739 complement(2673870..2674886) 1 NC_008563.1 thiosulfate transporter subunit 2674886 cysP 4495739 cysP Escherichia coli APEC O1 thiosulfate transporter subunit YP_853545.1 2673870 R 405955 CDS YP_853546.1 117624633 4495740 complement(2675044..2675835) 1 NC_008563.1 short chain dehydrogenase 2675835 ucpA 4495740 ucpA Escherichia coli APEC O1 short chain dehydrogenase YP_853546.1 2675044 R 405955 CDS YP_853547.1 117624634 4495741 2676115..2677011 1 NC_008563.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2677011 murQ 4495741 murQ Escherichia coli APEC O1 N-acetylmuramic acid 6-phosphate etherase YP_853547.1 2676115 D 405955 CDS YP_853548.1 117624635 4495742 2677015..2678439 1 NC_008563.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2678439 murP 4495742 murP Escherichia coli APEC O1 PTS system N-acetylmuramic acid transporter subunit IIBC YP_853548.1 2677015 D 405955 CDS YP_853550.1 117624637 4495744 complement(2679612..2680187) 1 NC_008563.1 hypothetical protein 2680187 yfdY 4495744 yfdY Escherichia coli APEC O1 hypothetical protein YP_853550.1 2679612 R 405955 CDS YP_853551.1 117624638 4495745 complement(2680248..2680697) 1 NC_008563.1 hypothetical protein 2680697 yfeZ 4495745 yfeZ Escherichia coli APEC O1 hypothetical protein YP_853551.1 2680248 R 405955 CDS YP_853552.1 117624639 4495746 complement(2680684..2681109) 1 NC_008563.1 acetyltransferase 2681109 ypeA 4495746 ypeA Escherichia coli APEC O1 acetyltransferase YP_853552.1 2680684 R 405955 CDS YP_853553.1 117624640 4495747 2681323..2682192 1 NC_008563.1 N-acetylmuramoyl-l-alanine amidase I 2682192 amiA 4495747 amiA Escherichia coli APEC O1 N-acetylmuramoyl-l-alanine amidase I YP_853553.1 2681323 D 405955 CDS YP_853554.1 117624641 4495748 2682196..2683095 1 NC_008563.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2683095 hemF 4495748 hemF Escherichia coli APEC O1 coproporphyrinogen III oxidase YP_853554.1 2682196 D 405955 CDS YP_853555.1 117624642 4495749 complement(2683101..2684153) 1 NC_008563.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2684153 yfeG 4495749 yfeG Escherichia coli APEC O1 transcriptional regulator EutR YP_853555.1 2683101 R 405955 CDS YP_853556.1 117624643 4494953 complement(2684199..2684699) 1 NC_008563.1 ethanolamine utilization protein EutK 2684699 eutK 4494953 eutK Escherichia coli APEC O1 ethanolamine utilization protein EutK YP_853556.1 2684199 R 405955 CDS YP_853557.1 117624644 4494954 complement(2684712..2685371) 1 NC_008563.1 ethanolamine utilization protein EutL 2685371 eutL 4494954 eutL Escherichia coli APEC O1 ethanolamine utilization protein EutL YP_853557.1 2684712 R 405955 CDS YP_853558.1 117624645 4494955 complement(2685381..2686268) 1 NC_008563.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2686268 eutC 4494955 eutC Escherichia coli APEC O1 ethanolamine ammonia-lyase small subunit YP_853558.1 2685381 R 405955 CDS YP_853559.1 117624646 4494956 complement(2686289..2687650) 1 NC_008563.1 regulatory subunit of ethanolamine ammonia-lyase 2687650 eutB 4494956 eutB Escherichia coli APEC O1 regulatory subunit of ethanolamine ammonia-lyase YP_853559.1 2686289 R 405955 CDS YP_853560.1 117624647 4494957 complement(2687662..2689065) 1 NC_008563.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2689065 eutA 4494957 eutA Escherichia coli APEC O1 reactivating factor for ethanolamine ammonia lyase YP_853560.1 2687662 R 405955 CDS YP_853561.1 117624648 4494958 complement(2689062..2690288) 1 NC_008563.1 ethanolamine utilization transport protein EutH 2690288 eutH 4494958 eutH Escherichia coli APEC O1 ethanolamine utilization transport protein EutH YP_853561.1 2689062 R 405955 CDS YP_853562.1 117624649 4494959 complement(2690505..2691719) 1 NC_008563.1 alcohol dehydrogenase in ethanolamine utilization 2691719 eutG 4494959 eutG Escherichia coli APEC O1 alcohol dehydrogenase in ethanolamine utilization YP_853562.1 2690505 R 405955 CDS YP_853563.1 117624650 4494960 complement(2691682..2692518) 1 NC_008563.1 chaperonin; ethanolamine utilization protein EutJ 2692518 eutJ 4494960 eutJ Escherichia coli APEC O1 ethanolamine utilization protein EutJ YP_853563.1 2691682 R 405955 CDS YP_853564.1 117624651 4494961 complement(2692529..2693932) 1 NC_008563.1 ethanolamine utilization protein EutE acetaldehyde dehydrogenase 2693932 eutE 4494961 eutE Escherichia coli APEC O1 ethanolamine utilization protein EutE acetaldehyde dehydrogenase YP_853564.1 2692529 R 405955 CDS YP_853565.1 117624652 4494962 complement(2693944..2694231) 1 NC_008563.1 carboxysome structural protein, ethanolamine utilization 2694231 cchB 4494962 cchB Escherichia coli APEC O1 carboxysome structural protein, ethanolamine utilization YP_853565.1 2693944 R 405955 CDS YP_853566.1 117624653 4494963 complement(2694338..2694673) 1 NC_008563.1 detox protein in ethanolamine utilization 2694673 eutM 4494963 eutM Escherichia coli APEC O1 detox protein in ethanolamine utilization YP_853566.1 2694338 R 405955 CDS YP_853567.1 117624654 4494964 complement(2694670..2695686) 1 NC_008563.1 ethanolamine utilization; in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2695686 eutD 4494964 eutD Escherichia coli APEC O1 phosphotransacetylase YP_853567.1 2694670 R 405955 CDS YP_853568.1 117624655 4494965 complement(2695683..2696486) 1 NC_008563.1 cobalamin adenosyltransferase 2696486 eutT 4494965 eutT Escherichia coli APEC O1 cobalamin adenosyltransferase YP_853568.1 2695683 R 405955 CDS YP_853569.1 117624656 4494966 complement(2696483..2697184) 1 NC_008563.1 ethanolamine utilization protein EutQ 2697184 eutQ 4494966 eutQ Escherichia coli APEC O1 ethanolamine utilization protein EutQ YP_853569.1 2696483 R 405955 CDS YP_853570.1 117624657 4494967 complement(2697159..2697638) 1 NC_008563.1 ethanolamine utilization protein EutP 2697638 eutP 4494967 eutP Escherichia coli APEC O1 ethanolamine utilization protein EutP YP_853570.1 2697159 R 405955 CDS YP_853571.1 117624658 4494968 complement(2697651..2697986) 1 NC_008563.1 ethanolamine utilization protein EutS 2697986 eutS 4494968 eutS Escherichia coli APEC O1 ethanolamine utilization protein EutS YP_853571.1 2697651 R 405955 CDS YP_853572.1 117624659 4494969 complement(2698279..2700558) 1 NC_008563.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2700558 4494969 APECO1_4094 Escherichia coli APEC O1 malic enzyme YP_853572.1 2698279 R 405955 CDS YP_853573.1 117624660 4494970 2700847..2701797 1 NC_008563.1 transaldolase A 2701797 talA 4494970 talA Escherichia coli APEC O1 transaldolase A YP_853573.1 2700847 D 405955 CDS YP_853574.1 117624661 4494971 2701817..2703820 1 NC_008563.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2703820 tktB 4494971 tktB Escherichia coli APEC O1 transketolase YP_853574.1 2701817 D 405955 CDS YP_853575.1 117624662 4495289 complement(2703897..2704940) 1 NC_008563.1 hypothetical protein 2704940 ypfG 4495289 ypfG Escherichia coli APEC O1 hypothetical protein YP_853575.1 2703897 R 405955 CDS YP_853576.1 117624663 4495290 complement(2705066..2705641) 1 NC_008563.1 NUDIX hydrolase 2705641 yffH 4495290 yffH Escherichia coli APEC O1 NUDIX hydrolase YP_853576.1 2705066 R 405955 CDS YP_853577.1 117624664 4495291 complement(2705709..2707688) 1 NC_008563.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 2707688 aegA 4495291 aegA Escherichia coli APEC O1 oxidoreductase Fe-S binding subunit YP_853577.1 2705709 R 405955 CDS YP_853578.1 117624665 4495292 2707879..2709594 1 NC_008563.1 nitrate/nitrite sensor protein; nitrate/nitrite sensor protein NarQ 2709594 narQ 4495292 narQ Escherichia coli APEC O1 nitrate/nitrite sensor protein NarQ YP_853578.1 2707879 D 405955 CDS YP_853579.1 117624666 4495293 2709758..2712871 1 NC_008563.1 aminoglycoside/multidrug efflux system 2712871 acrD 4495293 acrD Escherichia coli APEC O1 aminoglycoside/multidrug efflux system YP_853579.1 2709758 D 405955 CDS YP_853580.1 117624667 4495294 2713410..2713766 1 NC_008563.1 hypothetical protein 2713766 yffB 4495294 yffB Escherichia coli APEC O1 hypothetical protein YP_853580.1 2713410 D 405955 CDS YP_853581.1 117624668 4495295 2713770..2714897 1 NC_008563.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2714897 dapE 4495295 dapE Escherichia coli APEC O1 succinyl-diaminopimelate desuccinylase YP_853581.1 2713770 D 405955 CDS YP_853582.1 117624669 4495296 complement(2715206..2715928) 1 NC_008563.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 2715928 ypfH 4495296 ypfH Escherichia coli APEC O1 esterase YpfH YP_853582.1 2715206 R 405955 CDS YP_853583.1 117624670 4495297 complement(2715978..2717993) 1 NC_008563.1 hydrolase; hypothetical protein 2717993 ypfI 4495297 ypfI Escherichia coli APEC O1 hypothetical protein YP_853583.1 2715978 R 405955 CDS YP_853584.1 117624671 4495298 complement(2718008..2718871) 1 NC_008563.1 metalloprotease; hypothetical protein 2718871 ypfJ 4495298 ypfJ Escherichia coli APEC O1 hypothetical protein YP_853584.1 2718008 R 405955 CDS YP_853585.1 117624672 4495299 complement(2719039..2719761) 1 NC_008563.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2719761 purC 4495299 purC Escherichia coli APEC O1 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_853585.1 2719039 R 405955 CDS YP_853586.1 117624673 4495300 complement(2719965..2720999) 1 NC_008563.1 lipoprotein 2720999 nlpB 4495300 nlpB Escherichia coli APEC O1 lipoprotein YP_853586.1 2719965 R 405955 CDS YP_853587.1 117624674 4495301 complement(2721016..2721894) 1 NC_008563.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2721894 dapA 4495301 dapA Escherichia coli APEC O1 dihydrodipicolinate synthase YP_853587.1 2721016 R 405955 CDS YP_853588.1 117624675 4495302 2722067..2722612 1 NC_008563.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2722612 gcvR 4495302 gcvR Escherichia coli APEC O1 glycine cleavage system transcriptional repressor YP_853588.1 2722067 D 405955 CDS YP_853589.1 117624676 4495303 2722612..2723082 1 NC_008563.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2723082 bcp 4495303 bcp Escherichia coli APEC O1 thioredoxin-dependent thiol peroxidase YP_853589.1 2722612 D 405955 CDS YP_853590.1 117624677 4495304 complement(2723181..2724242) 1 NC_008563.1 permease PerM 2724242 yfgO 4495304 yfgO Escherichia coli APEC O1 permease PerM YP_853590.1 2723181 R 405955 CDS YP_853591.1 117624678 4495305 2724455..2725918 1 NC_008563.1 peptidase YfgC 2725918 yfgC 4495305 yfgC Escherichia coli APEC O1 peptidase YfgC YP_853591.1 2724455 D 405955 CDS YP_853592.1 117624679 4495306 2725939..2726298 1 NC_008563.1 oxidoreductase YfgD 2726298 yfgD 4495306 yfgD Escherichia coli APEC O1 oxidoreductase YfgD YP_853592.1 2725939 D 405955 CDS YP_853593.1 117624680 4495307 complement(2726436..2727182) 1 NC_008563.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2727182 had 4495307 had Escherichia coli APEC O1 DNA replication initiation factor YP_853593.1 2726436 R 405955 CDS YP_853594.1 117624681 4495068 complement(2727232..2728521) 1 NC_008563.1 uracil transporter 2728521 uraA 4495068 uraA Escherichia coli APEC O1 uracil transporter YP_853594.1 2727232 R 405955 CDS YP_853595.1 117624682 4495069 complement(2728607..2729233) 1 NC_008563.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2729233 upp 4495069 upp Escherichia coli APEC O1 uracil phosphoribosyltransferase YP_853595.1 2728607 R 405955 CDS YP_853596.1 117624683 4495070 2729542..2730594 1 NC_008563.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2730594 purM 4495070 purM Escherichia coli APEC O1 phosphoribosylaminoimidazole synthetase YP_853596.1 2729542 D 405955 CDS YP_853597.1 117624684 4495071 2730594..2731232 1 NC_008563.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2731232 purN 4495071 purN Escherichia coli APEC O1 phosphoribosylglycinamide formyltransferase YP_853597.1 2730594 D 405955 CDS YP_853598.1 117624685 4495072 2731404..2733470 1 NC_008563.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2733470 ppk 4495072 ppk Escherichia coli APEC O1 polyphosphate kinase YP_853598.1 2731404 D 405955 CDS YP_853599.1 117624686 4495073 2733475..2735016 1 NC_008563.1 exopolyphosphatase 2735016 ppx 4495073 ppx Escherichia coli APEC O1 exopolyphosphatase YP_853599.1 2733475 D 405955 CDS YP_853600.1 117624687 4495074 complement(2735113..2737299) 1 NC_008563.1 inner membrane protein; hypothetical protein 2737299 yfgF 4495074 yfgF Escherichia coli APEC O1 hypothetical protein YP_853600.1 2735113 R 405955 CDS YP_853601.1 117624688 4495075 complement(2737516..2737782) 1 NC_008563.1 hypothetical protein 2737782 4495075 APECO1_4065 Escherichia coli APEC O1 hypothetical protein YP_853601.1 2737516 R 405955 CDS YP_853602.1 117624689 4495076 2738153..2738671 1 NC_008563.1 outer membrane lipoprotein 2738671 yfgH 4495076 yfgH Escherichia coli APEC O1 outer membrane lipoprotein YP_853602.1 2738153 D 405955 CDS YP_853603.1 117624690 4495077 2738687..2739226 1 NC_008563.1 hypothetical protein 2739226 yfgI 4495077 yfgI Escherichia coli APEC O1 hypothetical protein YP_853603.1 2738687 D 405955 CDS YP_853604.1 117624691 4495078 complement(2739422..2739919) 1 NC_008563.1 phage lysis protein 2739919 4495078 APECO1_4062 Escherichia coli APEC O1 phage lysis protein YP_853604.1 2739422 R 405955 CDS YP_853605.1 117624692 4495079 complement(2739916..2740545) 1 NC_008563.1 phage-associated; endolysin 2740545 4495079 APECO1_4061 Escherichia coli APEC O1 endolysin YP_853605.1 2739916 R 405955 CDS YP_853606.1 117624693 4495080 complement(2740535..2740843) 1 NC_008563.1 holin 2740843 4495080 APECO1_4060 Escherichia coli APEC O1 holin YP_853606.1 2740535 R 405955 CDS YP_853607.1 117624694 4492738 complement(2740830..2741234) 1 NC_008563.1 phage-associated; hypothetical protein 2741234 4492738 APECO1_4059 Escherichia coli APEC O1 hypothetical protein YP_853607.1 2740830 R 405955 CDS YP_853608.1 117624695 4492739 complement(2741541..2744660) 1 NC_008563.1 similar to endo-N-acetylneuraminidase; hypothetical protein 2744660 4492739 APECO1_4058 Escherichia coli APEC O1 hypothetical protein YP_853608.1 2741541 R 405955 CDS YP_853609.1 117624696 4492740 2744733..2745113 1 NC_008563.1 phage-associated; hypothetical protein 2745113 4492740 APECO1_4057 Escherichia coli APEC O1 hypothetical protein YP_853609.1 2744733 D 405955 CDS YP_853610.1 117624697 4492741 2745429..2746124 1 NC_008563.1 phage-associated; anti-repressor protein 2746124 4492741 APECO1_4056 Escherichia coli APEC O1 anti-repressor protein YP_853610.1 2745429 D 405955 CDS YP_853611.1 117624698 4492742 complement(2747195..2747611) 1 NC_008563.1 hypothetical protein 2747611 4492742 APECO1_4055 Escherichia coli APEC O1 hypothetical protein YP_853611.1 2747195 R 405955 CDS YP_853612.1 117624699 4492743 complement(2747795..2750269) 1 NC_008563.1 phage-associated; hypothetical protein 2750269 4492743 APECO1_4054 Escherichia coli APEC O1 hypothetical protein YP_853612.1 2747795 R 405955 CDS YP_853613.1 117624700 4492744 complement(2750275..2752077) 1 NC_008563.1 phage-associated; hypothetical protein 2752077 4492744 APECO1_4053 Escherichia coli APEC O1 hypothetical protein YP_853613.1 2750275 R 405955 CDS YP_853614.1 117624701 4492745 complement(2752074..2754587) 1 NC_008563.1 phage-associated; hypothetical protein 2754587 4492745 APECO1_4052 Escherichia coli APEC O1 hypothetical protein YP_853614.1 2752074 R 405955 CDS YP_853615.1 117624702 4492746 complement(2754600..2755139) 1 NC_008563.1 phage-associated; hypothetical protein 2755139 4492746 APECO1_4051 Escherichia coli APEC O1 hypothetical protein YP_853615.1 2754600 R 405955 CDS YP_853616.1 117624703 4492747 complement(2755139..2755603) 1 NC_008563.1 phage-associated; hypothetical protein 2755603 4492747 APECO1_4050 Escherichia coli APEC O1 hypothetical protein YP_853616.1 2755139 R 405955 CDS YP_853617.1 117624704 4492748 complement(2755603..2758074) 1 NC_008563.1 phage-associated; hypothetical protein 2758074 4492748 APECO1_4049 Escherichia coli APEC O1 hypothetical protein YP_853617.1 2755603 R 405955 CDS YP_853618.1 117624705 4492749 complement(2758074..2758679) 1 NC_008563.1 phage-associated; hypothetical protein 2758679 4492749 APECO1_4048 Escherichia coli APEC O1 hypothetical protein YP_853618.1 2758074 R 405955 CDS YP_853619.1 117624706 4492750 complement(2758679..2759008) 1 NC_008563.1 phage-associated; hypothetical protein 2759008 4492750 APECO1_4047 Escherichia coli APEC O1 hypothetical protein YP_853619.1 2758679 R 405955 CDS YP_853620.1 117624707 4492751 complement(2759053..2759397) 1 NC_008563.1 phage-associated; hypothetical protein 2759397 4492751 APECO1_4046 Escherichia coli APEC O1 hypothetical protein YP_853620.1 2759053 R 405955 CDS YP_853621.1 117624708 4492752 complement(2759399..2759836) 1 NC_008563.1 phage-associated; hypothetical protein 2759836 4492752 APECO1_4045 Escherichia coli APEC O1 hypothetical protein YP_853621.1 2759399 R 405955 CDS YP_853622.1 117624709 4492753 complement(2759888..2760880) 1 NC_008563.1 phage-associated; hypothetical protein 2760880 4492753 APECO1_4044 Escherichia coli APEC O1 hypothetical protein YP_853622.1 2759888 R 405955 CDS YP_853623.1 117624710 4492754 complement(2760889..2761590) 1 NC_008563.1 phage-associated; hypothetical protein 2761590 4492754 APECO1_4043 Escherichia coli APEC O1 hypothetical protein YP_853623.1 2760889 R 405955 CDS YP_853624.1 117624711 4492755 complement(2761587..2761883) 1 NC_008563.1 phage-associated; hypothetical protein 2761883 4492755 APECO1_4042 Escherichia coli APEC O1 hypothetical protein YP_853624.1 2761587 R 405955 CDS YP_853625.1 117624712 4492756 complement(2761880..2763559) 1 NC_008563.1 phage-associated; tail protein 2763559 4492756 APECO1_4041 Escherichia coli APEC O1 tail protein YP_853625.1 2761880 R 405955 CDS YP_853627.1 117624714 4495692 2764483..2764863 1 NC_008563.1 phage-associated; hypothetical protein 2764863 4495692 APECO1_4039 Escherichia coli APEC O1 hypothetical protein YP_853627.1 2764483 D 405955 CDS YP_853628.1 117624715 4495693 complement(2764954..2766429) 1 NC_008563.1 phage terminase, large subunit 2766429 4495693 APECO1_4038 Escherichia coli APEC O1 phage terminase, large subunit YP_853628.1 2764954 R 405955 CDS YP_853629.1 117624716 4495694 complement(2766426..2767031) 1 NC_008563.1 phage terminase small subunit 2767031 4495694 APECO1_4037 Escherichia coli APEC O1 phage terminase small subunit YP_853629.1 2766426 R 405955 CDS YP_853630.1 117624717 4495695 complement(2767327..2767674) 1 NC_008563.1 phage-associated; hypothetical protein 2767674 4495695 APECO1_4036 Escherichia coli APEC O1 hypothetical protein YP_853630.1 2767327 R 405955 CDS YP_853631.1 117624718 4495696 complement(2767780..2768310) 1 NC_008563.1 phage-associated; hypothetical protein 2768310 4495696 APECO1_4035 Escherichia coli APEC O1 hypothetical protein YP_853631.1 2767780 R 405955 CDS YP_853632.1 117624719 4495697 complement(2768307..2768720) 1 NC_008563.1 phage-associated; hypothetical protein 2768720 4495697 APECO1_4034 Escherichia coli APEC O1 hypothetical protein YP_853632.1 2768307 R 405955 CDS YP_853633.1 117624720 4495698 complement(2768886..2769203) 1 NC_008563.1 phage-associated; hypothetical protein 2769203 4495698 APECO1_4033 Escherichia coli APEC O1 hypothetical protein YP_853633.1 2768886 R 405955 CDS YP_853634.1 117624721 4495699 complement(2769200..2769679) 1 NC_008563.1 phage-associated; hypothetical protein 2769679 4495699 APECO1_4032 Escherichia coli APEC O1 hypothetical protein YP_853634.1 2769200 R 405955 CDS YP_853635.1 117624722 4495700 complement(2769741..2770085) 1 NC_008563.1 phage-associated; hypothetical protein 2770085 4495700 APECO1_4031 Escherichia coli APEC O1 hypothetical protein YP_853635.1 2769741 R 405955 CDS YP_853636.1 117624723 4495701 complement(2770203..2770979) 1 NC_008563.1 hypothetical protein 2770979 4495701 APECO1_4030 Escherichia coli APEC O1 hypothetical protein YP_853636.1 2770203 R 405955 CDS YP_853637.1 117624724 4495702 complement(2770951..2771799) 1 NC_008563.1 hypothetical protein 2771799 4495702 APECO1_4029 Escherichia coli APEC O1 hypothetical protein YP_853637.1 2770951 R 405955 CDS YP_853638.1 117624725 4495703 2772508..2773092 1 NC_008563.1 repressor protein 2773092 4495703 APECO1_4028 Escherichia coli APEC O1 repressor protein YP_853638.1 2772508 D 405955 CDS YP_853639.1 117624726 4495704 2773386..2773700 1 NC_008563.1 hypothetical protein 2773700 4495704 APECO1_4027 Escherichia coli APEC O1 hypothetical protein YP_853639.1 2773386 D 405955 CDS YP_853640.1 117624727 4495705 2773697..2774596 1 NC_008563.1 phage-associated; hypothetical protein 2774596 4495705 APECO1_4026 Escherichia coli APEC O1 hypothetical protein YP_853640.1 2773697 D 405955 CDS YP_853641.1 117624728 4495706 2774606..2775628 1 NC_008563.1 phage recombinase; recombination and repair protein RecT 2775628 recT 4495706 recT Escherichia coli APEC O1 recombination and repair protein RecT YP_853641.1 2774606 D 405955 CDS YP_853642.1 117624729 4495707 2775678..2775926 1 NC_008563.1 phage regulatory protein 2775926 4495707 APECO1_4024 Escherichia coli APEC O1 phage regulatory protein YP_853642.1 2775678 D 405955 CDS YP_853643.1 117624730 4495708 2776036..2776335 1 NC_008563.1 hypothetical protein 2776335 4495708 APECO1_4023 Escherichia coli APEC O1 hypothetical protein YP_853643.1 2776036 D 405955 CDS YP_853644.1 117624731 4495709 2776328..2776978 1 NC_008563.1 phage-associated; adenine methylase 2776978 4495709 APECO1_4022 Escherichia coli APEC O1 adenine methylase YP_853644.1 2776328 D 405955 CDS YP_853645.1 117624732 4495710 2776855..2777634 1 NC_008563.1 diadenosine tetraphosphatase and related serine/threonine protein phosphatases COG; hypothetical protein 2777634 4495710 APECO1_4021 Escherichia coli APEC O1 hypothetical protein YP_853645.1 2776855 D 405955 CDS YP_853646.1 117624733 4494219 complement(2777637..2778893) 1 NC_008563.1 phage-associated; integrase-like protein 2778893 4494219 APECO1_4020 Escherichia coli APEC O1 integrase-like protein YP_853646.1 2777637 R 405955 CDS YP_853647.1 117624734 4494220 complement(2779086..2780663) 1 NC_008563.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2780663 guaA 4494220 guaA Escherichia coli APEC O1 GMP synthase YP_853647.1 2779086 R 405955 CDS YP_853648.1 117624735 4494221 complement(2780732..2782267) 1 NC_008563.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2782267 guaB 4494221 guaB Escherichia coli APEC O1 inosine 5'-monophosphate dehydrogenase YP_853648.1 2780732 R 405955 CDS YP_853649.1 117624736 4494222 2782360..2783736 1 NC_008563.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2783736 xseA 4494222 xseA Escherichia coli APEC O1 exodeoxyribonuclease VII large subunit YP_853649.1 2782360 D 405955 CDS YP_853650.1 117624737 4494223 complement(2783805..2791856) 1 NC_008563.1 RatA-like protein 2791856 4494223 APECO1_4016 Escherichia coli APEC O1 RatA-like protein YP_853650.1 2783805 R 405955 CDS YP_853651.1 117624738 4494224 complement(2791977..2792954) 1 NC_008563.1 SinI-like protein 2792954 sinI 4494224 sinI Escherichia coli APEC O1 SinI-like protein YP_853651.1 2791977 R 405955 CDS YP_853652.1 117624739 4494225 complement(2793009..2795240) 1 NC_008563.1 intimin/invasin 2795240 sinH 4494225 sinH Escherichia coli APEC O1 intimin/invasin YP_853652.1 2793009 R 405955 CDS YP_853653.1 117624740 4494226 complement(2795727..2797238) 1 NC_008563.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2797238 engA 4494226 engA Escherichia coli APEC O1 GTP-binding protein EngA YP_853653.1 2795727 R 405955 CDS YP_853654.1 117624741 4494227 complement(2797317..2798495) 1 NC_008563.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2798495 yfgL 4494227 yfgL Escherichia coli APEC O1 outer membrane protein assembly complex subunit YfgL YP_853654.1 2797317 R 405955 CDS YP_853655.1 117624742 4494228 complement(2798506..2799126) 1 NC_008563.1 hypothetical protein 2799126 yfgM 4494228 yfgM Escherichia coli APEC O1 hypothetical protein YP_853655.1 2798506 R 405955 CDS YP_853656.1 117624743 4494229 complement(2799144..2800418) 1 NC_008563.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2800418 hisS 4494229 hisS Escherichia coli APEC O1 histidyl-tRNA synthetase YP_853656.1 2799144 R 405955 CDS YP_853657.1 117624744 4494230 complement(2800529..2801647) 1 NC_008563.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2801647 ispG 4494230 ispG Escherichia coli APEC O1 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_853657.1 2800529 R 405955 CDS YP_853658.1 117624745 4494231 complement(2801674..2802681) 1 NC_008563.1 cytoskeletal protein RodZ 2802681 yfgA 4494231 yfgA Escherichia coli APEC O1 cytoskeletal protein RodZ YP_853658.1 2801674 R 405955 CDS YP_853659.1 117624746 4494232 complement(2802966..2804120) 1 NC_008563.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2804120 yfgB 4494232 yfgB Escherichia coli APEC O1 ribosomal RNA large subunit methyltransferase N YP_853659.1 2802966 R 405955 CDS YP_853660.1 117624747 4494233 complement(2804270..2804701) 1 NC_008563.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2804701 ndk 4494233 ndk Escherichia coli APEC O1 nucleoside diphosphate kinase YP_853660.1 2804270 R 405955 CDS YP_853661.1 117624748 4494234 complement(2804850..2807162) 1 NC_008563.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2807162 pbpC 4494234 pbpC Escherichia coli APEC O1 penicillin-binding protein 1C YP_853661.1 2804850 R 405955 CDS YP_853662.1 117624749 4494235 complement(2807163..2812124) 1 NC_008563.1 lipoprotein YfhM 2812124 yfhM 4494235 yfhM Escherichia coli APEC O1 lipoprotein YfhM YP_853662.1 2807163 R 405955 CDS YP_853663.1 117624750 4494236 2812172..2813176 1 NC_008563.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2813176 sseA 4494236 sseA Escherichia coli APEC O1 3-mercaptopyruvate sulfurtransferase YP_853663.1 2812172 D 405955 CDS YP_853664.1 117624751 4494237 complement(2813669..2814454) 1 NC_008563.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2814454 sseB 4494237 sseB Escherichia coli APEC O1 enhanced serine sensitivity protein SseB YP_853664.1 2813669 R 405955 CDS YP_853665.1 117624752 4492348 complement(2814587..2815870) 1 NC_008563.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 2815870 pepB 4492348 pepB Escherichia coli APEC O1 aminopeptidase B YP_853665.1 2814587 R 405955 CDS YP_853666.1 117624753 4492349 complement(2816141..2816476) 1 NC_008563.1 [2Fe-2S] ferredoxin 2816476 fdx 4492349 fdx Escherichia coli APEC O1 [2Fe-2S] ferredoxin YP_853666.1 2816141 R 405955 CDS YP_853667.1 117624754 4492350 complement(2816478..2818382) 1 NC_008563.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2818382 hscA 4492350 hscA Escherichia coli APEC O1 chaperone protein HscA YP_853667.1 2816478 R 405955 CDS YP_853668.1 117624755 4492351 complement(2818345..2818860) 1 NC_008563.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2818860 hscB 4492351 hscB Escherichia coli APEC O1 co-chaperone HscB YP_853668.1 2818345 R 405955 CDS YP_853669.1 117624756 4492352 complement(2818956..2819279) 1 NC_008563.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2819279 iscA 4492352 iscA Escherichia coli APEC O1 iron-sulfur cluster assembly protein YP_853669.1 2818956 R 405955 CDS YP_853670.1 117624757 4492353 complement(2819296..2819682) 1 NC_008563.1 scaffold protein 2819682 iscU 4492353 iscU Escherichia coli APEC O1 scaffold protein YP_853670.1 2819296 R 405955 CDS YP_853671.1 117624758 4492354 complement(2819710..2820948) 1 NC_008563.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2820948 iscS 4492354 iscS Escherichia coli APEC O1 cysteine desulfurase YP_853671.1 2819710 R 405955 CDS YP_853672.1 117624759 4492355 complement(2821036..2821524) 1 NC_008563.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2821524 iscR 4492355 iscR Escherichia coli APEC O1 DNA-binding transcriptional regulator IscR YP_853672.1 2821036 R 405955 CDS YP_853673.1 117624760 4492356 complement(2821794..2822534) 1 NC_008563.1 methyltransferase 2822534 yfhQ 4492356 yfhQ Escherichia coli APEC O1 methyltransferase YP_853673.1 2821794 R 405955 CDS YP_853674.1 117624761 4492357 2822653..2823456 1 NC_008563.1 inositol monophosphatase 2823456 suhB 4492357 suhB Escherichia coli APEC O1 inositol monophosphatase YP_853674.1 2822653 D 405955 CDS YP_853675.1 117624762 4492358 2823574..2824455 1 NC_008563.1 peptidase 2824455 yfhR 4492358 yfhR Escherichia coli APEC O1 peptidase YP_853675.1 2823574 D 405955 CDS YP_853676.1 117624763 4492359 2824625..2825926 1 NC_008563.1 stationary phase inducible protein CsiE 2825926 csiE 4492359 csiE Escherichia coli APEC O1 stationary phase inducible protein CsiE YP_853676.1 2824625 D 405955 CDS YP_853677.1 117624764 4492360 complement(2825918..2827057) 1 NC_008563.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 2827057 hcaT 4492360 hcaT Escherichia coli APEC O1 3-phenylpropionic acid transporter YP_853677.1 2825918 R 405955 CDS YP_853678.1 117624765 4492361 2827381..2827848 1 NC_008563.1 hypothetical protein 2827848 yphA 4492361 yphA Escherichia coli APEC O1 hypothetical protein YP_853678.1 2827381 D 405955 CDS YP_853679.1 117624766 4492362 complement(2828008..2828880) 1 NC_008563.1 hypothetical protein 2828880 yphB 4492362 yphB Escherichia coli APEC O1 hypothetical protein YP_853679.1 2828008 R 405955 CDS YP_853680.1 117624767 4492363 complement(2828892..2829986) 1 NC_008563.1 oxidoreductase, Zn-dependent and NAD(P)-binding 2829986 yphC 4492363 yphC Escherichia coli APEC O1 oxidoreductase, Zn-dependent and NAD(P)-binding YP_853680.1 2828892 R 405955 CDS YP_853681.1 117624768 4492364 complement(2830019..2831017) 1 NC_008563.1 sugar ABC transporter permease 2831017 yphD 4492364 yphD Escherichia coli APEC O1 sugar ABC transporter permease YP_853681.1 2830019 R 405955 CDS YP_853682.1 117624769 4492365 complement(2831042..2832553) 1 NC_008563.1 sugar ABC transporter ATP-binding protein 2832553 yphE 4492365 yphE Escherichia coli APEC O1 sugar ABC transporter ATP-binding protein YP_853682.1 2831042 R 405955 CDS YP_853683.1 117624770 4492366 complement(2832576..2833559) 1 NC_008563.1 sugar ABC transporter periplasmic component YphF 2833559 yphF 4492366 yphF Escherichia coli APEC O1 sugar ABC transporter periplasmic component YphF YP_853683.1 2832576 R 405955 CDS YP_853684.1 117624771 4492367 complement(2833656..2836937) 1 NC_008563.1 TPR repeat domain; hypothetical protein 2836937 yphG 4492367 yphG Escherichia coli APEC O1 hypothetical protein YP_853684.1 2833656 R 405955 CDS YP_853685.1 117624772 4492368 2837055..2838248 1 NC_008563.1 transcriptional regulator YchA 2838248 ychA 4492368 ychA Escherichia coli APEC O1 transcriptional regulator YchA YP_853685.1 2837055 D 405955 CDS YP_853686.1 117624773 4492369 complement(2838312..2839571) 1 NC_008563.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2839571 glyA 4492369 glyA Escherichia coli APEC O1 serine hydroxymethyltransferase YP_853686.1 2838312 R 405955 CDS YP_853687.1 117624774 4492370 2839894..2841084 1 NC_008563.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2841084 hmpA 4492370 hmpA Escherichia coli APEC O1 nitric oxide dioxygenase YP_853687.1 2839894 D 405955 CDS YP_853688.1 117624775 4492371 complement(2841129..2841467) 1 NC_008563.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2841467 glnB 4492371 glnB Escherichia coli APEC O1 nitrogen regulatory protein P-II 1 YP_853688.1 2841129 R 405955 CDS YP_853689.1 117624776 4492372 complement(2841528..2842901) 1 NC_008563.1 two component system DNA-binding response regulator 2842901 yfhA 4492372 yfhA Escherichia coli APEC O1 two component system DNA-binding response regulator YP_853689.1 2841528 R 405955 CDS YP_853690.1 117624777 4492373 complement(2842852..2843571) 1 NC_008563.1 hypothetical protein 2843571 yfhG 4492373 yfhG Escherichia coli APEC O1 hypothetical protein YP_853690.1 2842852 R 405955 CDS YP_853691.1 117624778 4492374 complement(2843730..2845112) 1 NC_008563.1 sensor-like histidine kinase YfhK 2845112 yfhK 4492374 yfhK Escherichia coli APEC O1 sensor-like histidine kinase YfhK YP_853691.1 2843730 R 405955 CDS YP_853692.1 117624779 4492375 complement(2845733..2849620) 1 NC_008563.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2849620 purL 4492375 purL Escherichia coli APEC O1 phosphoribosylformylglycinamidine synthase YP_853692.1 2845733 R 405955 CDS YP_853693.1 117624780 4492376 2850019..2851437 1 NC_008563.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2851437 yfhD 4492376 yfhD Escherichia coli APEC O1 transglycosylase YP_853693.1 2850019 D 405955 CDS YP_853694.1 117624781 4492377 complement(2851434..2851970) 1 NC_008563.1 tRNA-specific adenosine deaminase 2851970 tadA 4492377 tadA Escherichia coli APEC O1 tRNA-specific adenosine deaminase YP_853694.1 2851434 R 405955 CDS YP_853695.1 117624782 4492378 2852767..2853687 1 NC_008563.1 DNA-binding transcriptional regulator 2853687 yfhH 4492378 yfhH Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_853695.1 2852767 D 405955 CDS YP_853696.1 117624783 4492379 2853743..2854003 1 NC_008563.1 4Fe-4S binding protein 2854003 yfhL 4492379 yfhL Escherichia coli APEC O1 4Fe-4S binding protein YP_853696.1 2853743 D 405955 CDS YP_853697.1 117624784 4492380 complement(2854698..2855078) 1 NC_008563.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2855078 acpS 4492380 acpS Escherichia coli APEC O1 4'-phosphopantetheinyl transferase YP_853697.1 2854698 R 405955 CDS YP_853698.1 117624785 4492381 complement(2855078..2855824) 1 NC_008563.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2855824 pdxJ 4492381 pdxJ Escherichia coli APEC O1 pyridoxine 5'-phosphate synthase YP_853698.1 2855078 R 405955 CDS YP_853699.1 117624786 4492382 complement(2855821..2856549) 1 NC_008563.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2856549 recO 4492382 recO Escherichia coli APEC O1 DNA repair protein RecO YP_853699.1 2855821 R 405955 CDS YP_853700.1 117624787 4492383 complement(2856561..2857466) 1 NC_008563.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2857466 era 4492383 era Escherichia coli APEC O1 GTP-binding protein Era YP_853700.1 2856561 R 405955 CDS YP_853701.1 117624788 4492384 complement(2857463..2858143) 1 NC_008563.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2858143 rnc 4492384 rnc Escherichia coli APEC O1 ribonuclease III YP_853701.1 2857463 R 405955 CDS YP_853702.1 117624789 4492385 complement(2858410..2859384) 1 NC_008563.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2859384 lepB 4492385 lepB Escherichia coli APEC O1 signal peptidase I YP_853702.1 2858410 R 405955 CDS YP_853703.1 117624790 4492386 complement(2859400..2861199) 1 NC_008563.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2861199 lepA 4492386 lepA Escherichia coli APEC O1 GTP-binding protein LepA YP_853703.1 2859400 R 405955 CDS YP_853704.1 117624791 4495425 complement(2861397..2861876) 1 NC_008563.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2861876 rseC 4495425 rseC Escherichia coli APEC O1 SoxR reducing system protein RseC YP_853704.1 2861397 R 405955 CDS YP_853705.1 117624792 4495426 complement(2861873..2862829) 1 NC_008563.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2862829 rseB 4495426 rseB Escherichia coli APEC O1 periplasmic negative regulator of sigmaE YP_853705.1 2861873 R 405955 CDS YP_853706.1 117624793 4495427 complement(2862829..2863479) 1 NC_008563.1 anti-RNA polymerase sigma factor SigE 2863479 rseA 4495427 rseA Escherichia coli APEC O1 anti-RNA polymerase sigma factor SigE YP_853706.1 2862829 R 405955 CDS YP_853707.1 117624794 4495428 complement(2863512..2864120) 1 NC_008563.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2864120 rpoE 4495428 rpoE Escherichia coli APEC O1 RNA polymerase sigma factor RpoE YP_853707.1 2863512 R 405955 CDS YP_853708.1 117624795 4495429 2864495..2866117 1 NC_008563.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2866117 nadB 4495429 nadB Escherichia coli APEC O1 L-aspartate oxidase YP_853708.1 2864495 D 405955 CDS YP_853709.1 117624796 4495430 complement(2866102..2866959) 1 NC_008563.1 hypothetical protein 2866959 yfiC 4495430 yfiC Escherichia coli APEC O1 hypothetical protein YP_853709.1 2866102 R 405955 CDS YP_853710.1 117624797 4495431 2866971..2868305 1 NC_008563.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2868305 srmB 4495431 srmB Escherichia coli APEC O1 ATP-dependent RNA helicase SrmB YP_853710.1 2866971 D 405955 CDS YP_853711.1 117624798 4495432 complement(2868338..2869264) 1 NC_008563.1 transcriptional regulator YfiE 2869264 yfiE 4495432 yfiE Escherichia coli APEC O1 transcriptional regulator YfiE YP_853711.1 2868338 R 405955 CDS YP_853712.1 117624799 4495433 2869322..2869909 1 NC_008563.1 neutral amino acid efflux protein 2869909 yfiK 4495433 yfiK Escherichia coli APEC O1 neutral amino acid efflux protein YP_853712.1 2869322 D 405955 CDS YP_853713.1 117624800 4495434 complement(2869965..2870348) 1 NC_008563.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2870348 yfiD 4495434 yfiD Escherichia coli APEC O1 autonomous glycyl radical cofactor GrcA YP_853713.1 2869965 R 405955 CDS YP_853714.1 117624801 4495435 2870653..2871342 1 NC_008563.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2871342 ung 4495435 ung Escherichia coli APEC O1 uracil-DNA glycosylase YP_853714.1 2870653 D 405955 CDS YP_853715.1 117624802 4495436 complement(2871390..2871761) 1 NC_008563.1 tRNA/rRNA methyltransferase YfiF 2871761 yfiF 4495436 yfiF Escherichia coli APEC O1 tRNA/rRNA methyltransferase YfiF YP_853715.1 2871390 R 405955 CDS YP_853716.1 117624803 4495437 2871967..2872569 1 NC_008563.1 tRNA/rRNA methyltransferase YfiF 2872569 yfiF 4495437 yfiF Escherichia coli APEC O1 tRNA/rRNA methyltransferase YfiF YP_853716.1 2871967 D 405955 CDS YP_853717.1 117624804 4495438 2872638..2873057 1 NC_008563.1 thioredoxin 2873057 trxC 4495438 trxC Escherichia coli APEC O1 thioredoxin YP_853717.1 2872638 D 405955 CDS YP_853718.1 117624805 4495439 2873102..2873824 1 NC_008563.1 hypothetical protein 2873824 yfiP 4495439 yfiP Escherichia coli APEC O1 hypothetical protein YP_853718.1 2873102 D 405955 CDS YP_853719.1 117624806 4495440 2873856..2876516 1 NC_008563.1 acyl-CoA synthetase (NDP forming) 2876516 yfiQ 4495440 yfiQ Escherichia coli APEC O1 acyl-CoA synthetase (NDP forming) YP_853719.1 2873856 D 405955 CDS YP_853720.1 117624807 4495441 2876627..2877985 1 NC_008563.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2877985 pssA 4495441 pssA Escherichia coli APEC O1 phosphatidylserine synthase YP_853720.1 2876627 D 405955 CDS YP_853721.1 117624808 4495442 2878082..2878354 1 NC_008563.1 hypothetical protein 2878354 yfiM 4495442 yfiM Escherichia coli APEC O1 hypothetical protein YP_853721.1 2878082 D 405955 CDS YP_853722.1 117624809 4495443 complement(2878351..2879742) 1 NC_008563.1 alpha-ketoglutarate transporter 2879742 kgtP 4495443 kgtP Escherichia coli APEC O1 alpha-ketoglutarate transporter YP_853722.1 2878351 R 405955 CDS YP_853723.1 117624810 4495444 complement(2879972..2880307) 1 NC_008563.1 ISEc12 ATP-binding protein 2880307 4495444 APECO1_3944 Escherichia coli APEC O1 ISEc12 ATP-binding protein YP_853723.1 2879972 R 405955 CDS YP_853724.1 117624811 4493458 complement(2880735..2882276) 1 NC_008563.1 transposase for ISEc12 2882276 4493458 APECO1_3943 Escherichia coli APEC O1 transposase for ISEc12 YP_853724.1 2880735 R 405955 CDS YP_853725.1 117624812 4493459 2882841..2883272 1 NC_008563.1 hypothetical protein 2883272 4493459 APECO1_3942 Escherichia coli APEC O1 hypothetical protein YP_853725.1 2882841 D 405955 CDS YP_853726.1 117624813 4493460 complement(2883791..2884513) 1 NC_008563.1 transposase subunit 2884513 4493460 APECO1_3941 Escherichia coli APEC O1 transposase subunit YP_853726.1 2883791 R 405955 CDS YP_853727.1 117624814 4493461 complement(2884618..2884941) 1 NC_008563.1 transposase subunit 2884941 4493461 APECO1_3940 Escherichia coli APEC O1 transposase subunit YP_853727.1 2884618 R 405955 CDS YP_853729.1 117624816 4493463 complement(2890825..2893410) 1 NC_008563.1 chaperone; protein disaggregation chaperone 2893410 clpB 4493463 clpB Escherichia coli APEC O1 protein disaggregation chaperone YP_853729.1 2890825 R 405955 CDS YP_853730.1 117624817 4493464 complement(2893528..2894259) 1 NC_008563.1 hypothetical protein 2894259 yfiH 4493464 yfiH Escherichia coli APEC O1 hypothetical protein YP_853730.1 2893528 R 405955 CDS YP_853731.1 117624818 4493465 complement(2894256..2895236) 1 NC_008563.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2895236 rluD 4493465 rluD Escherichia coli APEC O1 23S rRNA pseudouridine synthase D YP_853731.1 2894256 R 405955 CDS YP_853732.1 117624819 4493466 2895371..2896108 1 NC_008563.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2896108 yfiO 4493466 yfiO Escherichia coli APEC O1 outer membrane protein assembly complex subunit YfiO YP_853732.1 2895371 D 405955 CDS YP_853733.1 117624820 4493467 2896969..2898129 1 NC_008563.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2898129 pheA 4493467 pheA Escherichia coli APEC O1 bifunctional chorismate mutase/prephenate dehydratase YP_853733.1 2896969 D 405955 CDS YP_853734.1 117624821 4493468 complement(2898172..2899293) 1 NC_008563.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 2899293 tyrA 4493468 tyrA Escherichia coli APEC O1 bifunctional chorismate mutase/prephenate dehydrogenase YP_853734.1 2898172 R 405955 CDS YP_853735.2 229775963 4493469 complement(2899304..2900374) 1 NC_008563.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2900374 aroF 4493469 aroF Escherichia coli APEC O1 phospho-2-dehydro-3-deoxyheptonate aldolase YP_853735.2 2899304 R 405955 CDS YP_853736.1 117624823 4493470 2900584..2900949 1 NC_008563.1 hypothetical protein 2900949 yfiL 4493470 yfiL Escherichia coli APEC O1 hypothetical protein YP_853736.1 2900584 D 405955 CDS YP_853737.1 117624824 4493471 2901098..2901616 1 NC_008563.1 hypothetical protein 2901616 yfiR 4493471 yfiR Escherichia coli APEC O1 hypothetical protein YP_853737.1 2901098 D 405955 CDS YP_853738.1 117624825 4493472 2901606..2902832 1 NC_008563.1 hypothetical protein 2902832 yfiN 4493472 yfiN Escherichia coli APEC O1 hypothetical protein YP_853738.1 2901606 D 405955 CDS YP_853739.1 117624826 4493473 2902848..2903330 1 NC_008563.1 outer membrane lipoprotein 2903330 yfiB 4493473 yfiB Escherichia coli APEC O1 outer membrane lipoprotein YP_853739.1 2902848 D 405955 CDS YP_853740.1 117624827 4493474 complement(2903407..2903754) 1 NC_008563.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2903754 rplS 4493474 rplS Escherichia coli APEC O1 50S ribosomal protein L19 YP_853740.1 2903407 R 405955 CDS YP_853741.1 117624828 4493475 complement(2903796..2904128) 1 NC_008563.1 tRNA (guanine-1-)-methyltransferase 2904128 trmD 4493475 trmD Escherichia coli APEC O1 tRNA (guanine-1-)-methyltransferase YP_853741.1 2903796 R 405955 CDS YP_853742.1 117624829 4493476 complement(2904206..2904565) 1 NC_008563.1 tRNA (guanine-1-)-methyltransferase 2904565 trmD 4493476 trmD Escherichia coli APEC O1 tRNA (guanine-1-)-methyltransferase YP_853742.1 2904206 R 405955 CDS YP_853743.1 117624830 4495386 complement(2904596..2905147) 1 NC_008563.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2905147 rimM 4495386 rimM Escherichia coli APEC O1 16S rRNA-processing protein RimM YP_853743.1 2904596 R 405955 CDS YP_853744.1 117624831 4495387 complement(2905163..2905471) 1 NC_008563.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2905471 rpsP 4495387 rpsP Escherichia coli APEC O1 30S ribosomal protein S16 YP_853744.1 2905163 R 405955 CDS YP_853745.1 117624832 4495388 complement(2905548..2906909) 1 NC_008563.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 2906909 ffh 4495388 ffh Escherichia coli APEC O1 signal recognition particle protein YP_853745.1 2905548 R 405955 CDS YP_853746.1 117624833 4495389 2907001..2907867 1 NC_008563.1 inner membrane protein; hypothetical protein 2907867 ypjD 4495389 ypjD Escherichia coli APEC O1 hypothetical protein YP_853746.1 2907001 D 405955 CDS YP_853747.1 117624834 4495390 2907933..2909174 1 NC_008563.1 hypothetical protein 2909174 4495390 APECO1_3921 Escherichia coli APEC O1 hypothetical protein YP_853747.1 2907933 D 405955 CDS YP_853748.1 117624835 4495391 2909196..2909948 1 NC_008563.1 hypothetical protein 2909948 4495391 APECO1_3920 Escherichia coli APEC O1 hypothetical protein YP_853748.1 2909196 D 405955 CDS YP_853749.1 117624836 4495392 2909945..2910823 1 NC_008563.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2910823 ppnK 4495392 ppnK Escherichia coli APEC O1 inorganic polyphosphate/ATP-NAD kinase YP_853749.1 2909945 D 405955 CDS YP_853750.1 117624837 4495393 2910909..2912570 1 NC_008563.1 recombination and repair protein 2912570 recN 4495393 recN Escherichia coli APEC O1 recombination and repair protein YP_853750.1 2910909 D 405955 CDS YP_853751.1 117624838 4495394 2912719..2913060 1 NC_008563.1 hypothetical protein 2913060 smpA 4495394 smpA Escherichia coli APEC O1 hypothetical protein YP_853751.1 2912719 D 405955 CDS YP_853752.1 117624839 4495395 complement(2913402..2913878) 1 NC_008563.1 hypothetical protein 2913878 yfjG 4495395 yfjG Escherichia coli APEC O1 hypothetical protein YP_853752.1 2913402 R 405955 CDS YP_853753.1 117624840 4495396 2914010..2914492 1 NC_008563.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2914492 smpB 4495396 smpB Escherichia coli APEC O1 SsrA-binding protein YP_853753.1 2914010 D 405955 CDS YP_853754.1 117624841 4495397 complement(2915071..2915325) 1 NC_008563.1 hypothetical protein 2915325 4495397 APECO1_3914 Escherichia coli APEC O1 hypothetical protein YP_853754.1 2915071 R 405955 CDS YP_853755.1 117624842 4495398 2915649..2916437 1 NC_008563.1 hypothetical protein 2916437 4495398 APECO1_3913 Escherichia coli APEC O1 hypothetical protein YP_853755.1 2915649 D 405955 CDS YP_853756.1 117624843 4495399 complement(2916525..2916818) 1 NC_008563.1 hypothetical protein 2916818 4495399 APECO1_39122 Escherichia coli APEC O1 hypothetical protein YP_853756.1 2916525 R 405955 CDS YP_853757.1 117624844 4495400 complement(2917029..2917802) 1 NC_008563.1 hypothetical protein 2917802 4495400 APECO1_3912 Escherichia coli APEC O1 hypothetical protein YP_853757.1 2917029 R 405955 CDS YP_853758.1 117624845 4495401 2918794..2920608 1 NC_008563.1 hypothetical protein 2920608 4495401 APECO1_3911 Escherichia coli APEC O1 hypothetical protein YP_853758.1 2918794 D 405955 CDS YP_853759.1 117624846 4495402 2920995..2921489 1 NC_008563.1 tail fiber protein 2921489 4495402 APECO1_3910 Escherichia coli APEC O1 tail fiber protein YP_853759.1 2920995 D 405955 CDS YP_853760.1 117624847 4495403 2921489..2922091 1 NC_008563.1 tail fiber assembly protein 2922091 4495403 APECO1_3909 Escherichia coli APEC O1 tail fiber assembly protein YP_853760.1 2921489 D 405955 CDS YP_853761.1 117624848 4495404 complement(2922063..2922506) 1 NC_008563.1 phage-associated; hypothetical protein 2922506 4495404 APECO1_3908 Escherichia coli APEC O1 hypothetical protein YP_853761.1 2922063 R 405955 CDS YP_853762.1 117624849 4495405 complement(2923256..2923840) 1 NC_008563.1 phage-associated; hypothetical protein 2923840 4495405 APECO1_3907 Escherichia coli APEC O1 hypothetical protein YP_853762.1 2923256 R 405955 CDS YP_853763.1 117624850 4494180 complement(2923831..2924889) 1 NC_008563.1 bacteriophage V tail protein 2924889 4494180 APECO1_3906 Escherichia coli APEC O1 bacteriophage V tail protein YP_853763.1 2923831 R 405955 CDS YP_853764.1 117624851 4494181 complement(2924876..2925304) 1 NC_008563.1 bacteriophage V tail protein 2925304 4494181 APECO1_3905 Escherichia coli APEC O1 bacteriophage V tail protein YP_853764.1 2924876 R 405955 CDS YP_853765.1 117624852 4494182 complement(2925301..2925849) 1 NC_008563.1 bacteriophage V tail protein 2925849 4494182 APECO1_3904 Escherichia coli APEC O1 bacteriophage V tail protein YP_853765.1 2925301 R 405955 CDS YP_853766.1 117624853 4494183 complement(2925849..2926928) 1 NC_008563.1 tail protein 2926928 4494183 APECO1_3903 Escherichia coli APEC O1 tail protein YP_853766.1 2925849 R 405955 CDS YP_853767.1 117624854 4494184 complement(2926925..2928295) 1 NC_008563.1 bacteriophage V tail/DNA circulation protein 2928295 4494184 APECO1_3902 Escherichia coli APEC O1 bacteriophage V tail/DNA circulation protein YP_853767.1 2926925 R 405955 CDS YP_853768.1 117624855 4494185 complement(2928314..2930149) 1 NC_008563.1 bacteriophage V tail protein 2930149 4494185 APECO1_3901 Escherichia coli APEC O1 bacteriophage V tail protein YP_853768.1 2928314 R 405955 CDS YP_853769.1 117624856 4494186 2930148..2930441 1 NC_008563.1 hypothetical protein 2930441 4494186 APECO1_3900 Escherichia coli APEC O1 hypothetical protein YP_853769.1 2930148 D 405955 CDS YP_853770.1 117624857 4494187 complement(2930560..2930916) 1 NC_008563.1 phage-associated; hypothetical protein 2930916 4494187 APECO1_3899 Escherichia coli APEC O1 hypothetical protein YP_853770.1 2930560 R 405955 CDS YP_853771.1 117624858 4494188 complement(2930916..2932412) 1 NC_008563.1 bacteriophage V tail sheath pro 2932412 4494188 APECO1_3898 Escherichia coli APEC O1 bacteriophage V tail sheath pro YP_853771.1 2930916 R 405955 CDS YP_853772.1 117624859 4494189 complement(2932575..2933135) 1 NC_008563.1 phage-associated; hypothetical protein 2933135 4494189 APECO1_3897 Escherichia coli APEC O1 hypothetical protein YP_853772.1 2932575 R 405955 CDS YP_853773.1 117624860 4494190 complement(2933132..2933638) 1 NC_008563.1 phage-associated; hypothetical protein 2933638 4494190 APECO1_3896 Escherichia coli APEC O1 hypothetical protein YP_853773.1 2933132 R 405955 CDS YP_853774.1 117624861 4494191 complement(2933613..2934023) 1 NC_008563.1 bacteriophage head tail adaptor 2934023 4494191 APECO1_3895 Escherichia coli APEC O1 bacteriophage head tail adaptor YP_853774.1 2933613 R 405955 CDS YP_853775.1 117624862 4494192 complement(2934020..2934343) 1 NC_008563.1 phage-associated; hypothetical protein 2934343 4494192 APECO1_3894 Escherichia coli APEC O1 hypothetical protein YP_853775.1 2934020 R 405955 CDS YP_853776.1 117624863 4494193 complement(2934596..2935801) 1 NC_008563.1 major capsid protein 2935801 4494193 APECO1_3893 Escherichia coli APEC O1 major capsid protein YP_853776.1 2934596 R 405955 CDS YP_853777.1 117624864 4494194 complement(2935816..2936502) 1 NC_008563.1 pro-head protease 2936502 4494194 APECO1_3892 Escherichia coli APEC O1 pro-head protease YP_853777.1 2935816 R 405955 CDS YP_853778.1 117624865 4494195 complement(2936444..2937559) 1 NC_008563.1 phage portal protein 2937559 4494195 APECO1_3891 Escherichia coli APEC O1 phage portal protein YP_853778.1 2936444 R 405955 CDS YP_853779.1 117624866 4494196 complement(2937879..2939612) 1 NC_008563.1 bacteriophage V large terminase subunit 2939612 4494196 APECO1_3890 Escherichia coli APEC O1 bacteriophage V large terminase subunit YP_853779.1 2937879 R 405955 CDS YP_853780.1 117624867 4494197 complement(2939609..2940103) 1 NC_008563.1 bacteriophage V small terminase subunit 2940103 4494197 APECO1_3889 Escherichia coli APEC O1 bacteriophage V small terminase subunit YP_853780.1 2939609 R 405955 CDS YP_853781.1 117624868 4494198 complement(2940229..2940579) 1 NC_008563.1 phage endonuclease 2940579 4494198 APECO1_3888 Escherichia coli APEC O1 phage endonuclease YP_853781.1 2940229 R 405955 CDS YP_853782.1 117624869 4491304 complement(2941550..2941987) 1 NC_008563.1 phage lysis protein 2941987 4491304 APECO1_3887 Escherichia coli APEC O1 phage lysis protein YP_853782.1 2941550 R 405955 CDS YP_853783.1 117624870 4491305 complement(2941984..2942460) 1 NC_008563.1 phage-associated; muramidase 2942460 4491305 APECO1_3886 Escherichia coli APEC O1 muramidase YP_853783.1 2941984 R 405955 CDS YP_853784.1 117624871 4491306 complement(2942447..2942851) 1 NC_008563.1 phage-associated; hypothetical protein 2942851 4491306 APECO1_3885 Escherichia coli APEC O1 hypothetical protein YP_853784.1 2942447 R 405955 CDS YP_853785.1 117624872 4491307 complement(2942904..2943239) 1 NC_008563.1 phage-associated; hypothetical protein 2943239 4491307 APECO1_3884 Escherichia coli APEC O1 hypothetical protein YP_853785.1 2942904 R 405955 CDS YP_853786.1 117624873 4491308 complement(2943425..2944177) 1 NC_008563.1 phage-associated; Qin-like prophage; antitermination protein Q 2944177 4491308 APECO1_3883 Escherichia coli APEC O1 Qin-like prophage; antitermination protein Q YP_853786.1 2943425 R 405955 CDS YP_853787.1 117624874 4491310 complement(2944191..2945144) 1 NC_008563.1 phage-associated; hypothetical protein 2945144 4491310 APECO1_3882 Escherichia coli APEC O1 hypothetical protein YP_853787.1 2944191 R 405955 CDS YP_853788.1 117624875 4491311 complement(2945188..2945985) 1 NC_008563.1 phage-associated; hypothetical protein 2945985 4491311 APECO1_3881 Escherichia coli APEC O1 hypothetical protein YP_853788.1 2945188 R 405955 CDS YP_853789.1 117624876 4491313 complement(2946005..2946394) 1 NC_008563.1 phage-associated; bacteriophage V crossover junction endodeoxyribonuclease 2946394 4491313 APECO1_3880 Escherichia coli APEC O1 bacteriophage V crossover junction endodeoxyribonuclease YP_853789.1 2946005 R 405955 CDS YP_853790.1 117624877 4491314 complement(2946391..2946717) 1 NC_008563.1 phage-associated; hypothetical protein 2946717 4491314 APECO1_3879 Escherichia coli APEC O1 hypothetical protein YP_853790.1 2946391 R 405955 CDS YP_853791.1 117624878 4491315 complement(2946714..2947367) 1 NC_008563.1 phage-associated; DNA adenine methylase 2947367 4491315 APECO1_3878 Escherichia coli APEC O1 DNA adenine methylase YP_853791.1 2946714 R 405955 CDS YP_853792.1 117624879 4491316 complement(2947367..2947855) 1 NC_008563.1 phage-associated; hypothetical protein 2947855 4491316 APECO1_3877 Escherichia coli APEC O1 hypothetical protein YP_853792.1 2947367 R 405955 CDS YP_853793.1 117624880 4491318 complement(2947858..2948799) 1 NC_008563.1 phage-associated; hypothetical protein 2948799 4491318 APECO1_3876 Escherichia coli APEC O1 hypothetical protein YP_853793.1 2947858 R 405955 CDS YP_853794.1 117624881 4491319 complement(2948809..2949147) 1 NC_008563.1 phage-associated; hypothetical protein 2949147 ymfM 4491319 ymfM Escherichia coli APEC O1 hypothetical protein YP_853794.1 2948809 R 405955 CDS YP_853795.1 117624882 4491320 complement(2949144..2949707) 1 NC_008563.1 phage-associated; e14 prophage; DNA-binding transcriptional regulator 2949707 ymfL 4491320 ymfL Escherichia coli APEC O1 e14 prophage; DNA-binding transcriptional regulator YP_853795.1 2949144 R 405955 CDS YP_853796.1 117624883 4491321 complement(2949739..2950044) 1 NC_008563.1 phage-associated; hypothetical protein 2950044 4491321 APECO1_3873 Escherichia coli APEC O1 hypothetical protein YP_853796.1 2949739 R 405955 CDS YP_853797.1 117624884 4491322 2950030..2950704 1 NC_008563.1 phage-associated; phage repressor 2950704 4491322 APECO1_3872 Escherichia coli APEC O1 phage repressor YP_853797.1 2950030 D 405955 CDS YP_853798.1 117624885 4491323 complement(2950907..2951419) 1 NC_008563.1 hypothetical protein 2951419 4491323 APECO1_3871 Escherichia coli APEC O1 hypothetical protein YP_853798.1 2950907 R 405955 CDS YP_853799.1 117624886 4492445 2951570..2952250 1 NC_008563.1 hypothetical protein 2952250 4492445 APECO1_3870 Escherichia coli APEC O1 hypothetical protein YP_853799.1 2951570 D 405955 CDS YP_853800.1 117624887 4492446 2952316..2953140 1 NC_008563.1 hypothetical protein 2953140 yfdQ 4492446 yfdQ Escherichia coli APEC O1 hypothetical protein YP_853800.1 2952316 D 405955 CDS YP_853801.1 117624888 4492447 2953268..2953792 1 NC_008563.1 hypothetical protein 2953792 yfdR 4492447 yfdR Escherichia coli APEC O1 hypothetical protein YP_853801.1 2953268 D 405955 CDS YP_853802.1 117624889 4492448 2953901..2954767 1 NC_008563.1 hypothetical protein 2954767 4492448 APECO1_3867 Escherichia coli APEC O1 hypothetical protein YP_853802.1 2953901 D 405955 CDS YP_853803.1 117624890 4492449 2954976..2956148 1 NC_008563.1 hypothetical protein 2956148 4492449 APECO1_3866 Escherichia coli APEC O1 hypothetical protein YP_853803.1 2954976 D 405955 CDS YP_853804.1 117624891 4492450 complement(2956140..2956739) 1 NC_008563.1 hypothetical protein 2956739 4492450 APECO1_3865 Escherichia coli APEC O1 hypothetical protein YP_853804.1 2956140 R 405955 CDS YP_853805.1 117624892 4492451 complement(2956768..2957094) 1 NC_008563.1 hypothetical protein 2957094 4492451 APECO1_3864 Escherichia coli APEC O1 hypothetical protein YP_853805.1 2956768 R 405955 CDS YP_853806.1 117624893 4492452 complement(2957099..2958010) 1 NC_008563.1 hypothetical protein 2958010 4492452 APECO1_3863 Escherichia coli APEC O1 hypothetical protein YP_853806.1 2957099 R 405955 CDS YP_853807.1 117624894 4492453 2957976..2958239 1 NC_008563.1 hypothetical protein 2958239 4492453 APECO1_3862 Escherichia coli APEC O1 hypothetical protein YP_853807.1 2957976 D 405955 CDS YP_853808.1 117624895 4492454 2958871..2959848 1 NC_008563.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2959848 ygaT 4492454 ygaT Escherichia coli APEC O1 hypothetical protein YP_853808.1 2958871 D 405955 CDS YP_853809.1 117624896 4492455 2959868..2961136 1 NC_008563.1 dehydrogenase; catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2961136 ygaF 4492455 ygaF Escherichia coli APEC O1 hydroxyglutarate oxidase YP_853809.1 2959868 D 405955 CDS YP_853810.1 117624897 4492456 2961159..2962607 1 NC_008563.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2962607 gabD 4492456 gabD Escherichia coli APEC O1 succinate-semialdehyde dehydrogenase I YP_853810.1 2961159 D 405955 CDS YP_853811.1 117624898 4492457 2962615..2963901 1 NC_008563.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2963901 gabT 4492457 gabT Escherichia coli APEC O1 4-aminobutyrate aminotransferase YP_853811.1 2962615 D 405955 CDS YP_853812.1 117624899 4492458 2964076..2965539 1 NC_008563.1 gamma-aminobutyrate transporter 2965539 gabP 4492458 gabP Escherichia coli APEC O1 gamma-aminobutyrate transporter YP_853812.1 2964076 D 405955 CDS YP_853813.1 117624900 4492459 2965542..2966222 1 NC_008563.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2966222 ygaE 4492459 ygaE Escherichia coli APEC O1 DNA-binding transcriptional regulator CsiR YP_853813.1 2965542 D 405955 CDS YP_853814.1 117624901 4492460 complement(2966223..2966672) 1 NC_008563.1 LysM domain/BON superfamily protein 2966672 ygaU 4492460 ygaU Escherichia coli APEC O1 LysM domain/BON superfamily protein YP_853814.1 2966223 R 405955 CDS YP_853815.1 117624902 4492461 2967097..2967396 1 NC_008563.1 DNA-binding transcriptional regulator 2967396 ygaV 4492461 ygaV Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_853815.1 2967097 D 405955 CDS YP_853816.1 117624903 4492462 2967406..2967930 1 NC_008563.1 hypothetical protein 2967930 ygaP 4492462 ygaP Escherichia coli APEC O1 hypothetical protein YP_853816.1 2967406 D 405955 CDS YP_853817.1 117624904 4492463 complement(2967977..2968381) 1 NC_008563.1 DNA binding protein 2968381 stpA 4492463 stpA Escherichia coli APEC O1 DNA binding protein YP_853817.1 2967977 R 405955 CDS YP_853821.1 117624905 4493086 2969048..2969497 1 NC_008563.1 hypothetical protein 2969497 ygaW 4493086 ygaW Escherichia coli APEC O1 hypothetical protein YP_853821.1 2969048 D 405955 CDS YP_853831.1 117624906 4493087 complement(2969534..2969878) 1 NC_008563.1 hypothetical protein 2969878 ygaC 4493087 ygaC Escherichia coli APEC O1 hypothetical protein YP_853831.1 2969534 R 405955 CDS YP_853835.1 117624907 4493088 2970018..2970359 1 NC_008563.1 hypothetical protein 2970359 ygaM 4493088 ygaM Escherichia coli APEC O1 hypothetical protein YP_853835.1 2970018 D 405955 CDS YP_853846.1 117624908 4493089 complement(2970416..2971750) 1 NC_008563.1 GntR family transcriptional regulator 2971750 4493089 APECO1_3849 Escherichia coli APEC O1 GntR family transcriptional regulator YP_853846.1 2970416 R 405955 CDS YP_853848.1 117624909 4493090 2971838..2972269 1 NC_008563.1 hypothetical protein 2972269 4493090 APECO1_3848 Escherichia coli APEC O1 hypothetical protein YP_853848.1 2971838 D 405955 CDS YP_853850.1 117624910 4493091 2972720..2973130 1 NC_008563.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2973130 nrdI 4493091 nrdI Escherichia coli APEC O1 ribonucleotide reductase stimulatory protein YP_853850.1 2972720 D 405955 CDS YP_853851.1 117624911 4493092 2973142..2975247 1 NC_008563.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2975247 nrdE 4493092 nrdE Escherichia coli APEC O1 ribonucleotide-diphosphate reductase subunit alpha YP_853851.1 2973142 D 405955 CDS YP_853853.1 117624912 4493093 2975257..2976216 1 NC_008563.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2976216 nrdF 4493093 nrdF Escherichia coli APEC O1 ribonucleotide-diphosphate reductase subunit beta YP_853853.1 2975257 D 405955 CDS YP_853854.1 117624913 4493094 2976572..2977774 1 NC_008563.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2977774 proV 4493094 proV Escherichia coli APEC O1 glycine betaine transporter ATP-binding subunit YP_853854.1 2976572 D 405955 CDS YP_853857.1 117624914 4493095 2977767..2978831 1 NC_008563.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2978831 proW 4493095 proW Escherichia coli APEC O1 glycine betaine transporter membrane protein YP_853857.1 2977767 D 405955 CDS YP_853858.1 117624915 4493096 2978889..2979881 1 NC_008563.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2979881 proX 4493096 proX Escherichia coli APEC O1 glycine betaine transporter periplasmic subunit YP_853858.1 2978889 D 405955 CDS YP_853860.1 117624916 4493097 2980073..2981257 1 NC_008563.1 transporter 2981257 ygaY 4493097 ygaY Escherichia coli APEC O1 transporter YP_853860.1 2980073 D 405955 CDS YP_853863.1 117624917 4493098 2981381..2982118 1 NC_008563.1 hypothetical protein 2982118 ygaZ 4493098 ygaZ Escherichia coli APEC O1 hypothetical protein YP_853863.1 2981381 D 405955 CDS YP_853866.1 117624918 4493099 2982108..2982443 1 NC_008563.1 hypothetical protein 2982443 ygaH 4493099 ygaH Escherichia coli APEC O1 hypothetical protein YP_853866.1 2982108 D 405955 CDS YP_853870.1 117624919 4493100 2982534..2983064 1 NC_008563.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2983064 mprA 4493100 mprA Escherichia coli APEC O1 transcriptional repressor MprA YP_853870.1 2982534 D 405955 CDS YP_853871.1 117624920 4493101 2984380..2985918 1 NC_008563.1 multidrug resistance protein B 2985918 emrB 4493101 emrB Escherichia coli APEC O1 multidrug resistance protein B YP_853871.1 2984380 D 405955 CDS YP_853874.1 117624921 4493102 2986176..2986883 1 NC_008563.1 hypothetical protein 2986883 4493102 APECO1_3836 Escherichia coli APEC O1 hypothetical protein YP_853874.1 2986176 D 405955 CDS YP_853878.1 117624922 4493103 2986880..2987992 1 NC_008563.1 hypothetical protein 2987992 4493103 APECO1_3835 Escherichia coli APEC O1 hypothetical protein YP_853878.1 2986880 D 405955 CDS YP_853882.1 117624923 4493105 complement(2988043..2988558) 1 NC_008563.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2988558 luxS 4493105 luxS Escherichia coli APEC O1 S-ribosylhomocysteinase YP_853882.1 2988043 R 405955 CDS YP_853912.1 117624924 4493322 complement(2988709..2990031) 1 NC_008563.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 2990031 gshA 4493322 gshA Escherichia coli APEC O1 glutamate--cysteine ligase YP_853912.1 2988709 R 405955 CDS YP_853913.1 117624925 4493323 complement(2990338..2990673) 1 NC_008563.1 hypothetical protein 2990673 yqaA 4493323 yqaA Escherichia coli APEC O1 hypothetical protein YP_853913.1 2990338 R 405955 CDS YP_853914.1 117624926 4493324 complement(2990763..2991329) 1 NC_008563.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 2991329 yqaB 4493324 yqaB Escherichia coli APEC O1 fructose-1-phosphatase YP_853914.1 2990763 R 405955 CDS YP_853916.1 117624928 4493326 complement(2992939..2995569) 1 NC_008563.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2995569 alaS 4493326 alaS Escherichia coli APEC O1 alanyl-tRNA synthetase YP_853916.1 2992939 R 405955 CDS YP_853917.1 117624929 4493327 complement(2995697..2996197) 1 NC_008563.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2996197 recX 4493327 recX Escherichia coli APEC O1 recombination regulator RecX YP_853917.1 2995697 R 405955 CDS YP_853918.1 117624930 4493328 complement(2996266..2997342) 1 NC_008563.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2997342 recA 4493328 recA Escherichia coli APEC O1 recombinase A YP_853918.1 2996266 R 405955 CDS YP_853919.1 117624931 4493329 complement(2997407..2997904) 1 NC_008563.1 competence damage-inducible protein A 2997904 ygaD 4493329 ygaD Escherichia coli APEC O1 competence damage-inducible protein A YP_853919.1 2997407 R 405955 CDS YP_853920.1 117624932 4493330 complement(2998049..2999182) 1 NC_008563.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 2999182 mltB 4493330 mltB Escherichia coli APEC O1 murein hydrolase B YP_853920.1 2998049 R 405955 CDS YP_853921.1 117624933 4493331 2999391..2999954 1 NC_008563.1 PTS system, glucitol/sorbitol-specific IIC2 component 2999954 srlA 4493331 srlA Escherichia coli APEC O1 PTS system, glucitol/sorbitol-specific IIC2 component YP_853921.1 2999391 D 405955 CDS YP_853922.1 117624934 4493332 2999951..3000910 1 NC_008563.1 PTS system, glucitol/sorbitol-specific IIBC component 3000910 srlE 4493332 srlE Escherichia coli APEC O1 PTS system, glucitol/sorbitol-specific IIBC component YP_853922.1 2999951 D 405955 CDS YP_853923.1 117624935 4493333 3000921..3001292 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3001292 srlB 4493333 srlB Escherichia coli APEC O1 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_853923.1 3000921 D 405955 CDS YP_853924.1 117624936 4493334 3001296..3002075 1 NC_008563.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3002075 srlD 4493334 srlD Escherichia coli APEC O1 sorbitol-6-phosphate dehydrogenase YP_853924.1 3001296 D 405955 CDS YP_853925.1 117624937 4493335 3002181..3002540 1 NC_008563.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3002540 gutM 4493335 gutM Escherichia coli APEC O1 DNA-binding transcriptional activator GutM YP_853925.1 3002181 D 405955 CDS YP_853926.1 117624938 4493336 3002607..3003380 1 NC_008563.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3003380 srlR 4493336 srlR Escherichia coli APEC O1 DNA-binding transcriptional repressor SrlR YP_853926.1 3002607 D 405955 CDS YP_853927.1 117624939 4493339 3003373..3004338 1 NC_008563.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3004338 gutQ 4493339 gutQ Escherichia coli APEC O1 D-arabinose 5-phosphate isomerase YP_853927.1 3003373 D 405955 CDS YP_853928.1 117624940 4494837 complement(3004335..3005849) 1 NC_008563.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 3005849 ygaA 4494837 ygaA Escherichia coli APEC O1 anaerobic nitric oxide reductase transcriptional regulator YP_853928.1 3004335 R 405955 CDS YP_853929.1 117624941 4494838 3006036..3007475 1 NC_008563.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3007475 norV 4494838 norV Escherichia coli APEC O1 anaerobic nitric oxide reductase flavorubredoxin YP_853929.1 3006036 D 405955 CDS YP_853930.1 117624942 4494839 3007472..3008605 1 NC_008563.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3008605 ygbD 4494839 ygbD Escherichia coli APEC O1 nitric oxide reductase YP_853930.1 3007472 D 405955 CDS YP_853931.1 117624943 4494840 complement(3008829..3011081) 1 NC_008563.1 hydrogenase maturation protein HypF 3011081 hypF 4494840 hypF Escherichia coli APEC O1 hydrogenase maturation protein HypF YP_853931.1 3008829 R 405955 CDS YP_853932.1 117624944 4494841 complement(3011234..3011761) 1 NC_008563.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 3011761 hydN 4494841 hydN Escherichia coli APEC O1 electron transport protein HydN YP_853932.1 3011234 R 405955 CDS YP_853933.1 117624945 4494842 complement(3011910..3012929) 1 NC_008563.1 ascBF operon repressor 3012929 ascG 4494842 ascG Escherichia coli APEC O1 ascBF operon repressor YP_853933.1 3011910 R 405955 CDS YP_853934.1 117624946 4494843 3013180..3014637 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 3014637 ascF 4494843 ascF Escherichia coli APEC O1 PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_853934.1 3013180 D 405955 CDS YP_853935.1 117624947 4494844 3014640..3016070 1 NC_008563.1 cryptic 6-phospho-beta-glucosidase 3016070 ascB 4494844 ascB Escherichia coli APEC O1 cryptic 6-phospho-beta-glucosidase YP_853935.1 3014640 D 405955 CDS YP_853936.1 117624948 4494845 complement(3016168..3016587) 1 NC_008563.1 hypothetical protein 3016587 4494845 APECO1_3809 Escherichia coli APEC O1 hypothetical protein YP_853936.1 3016168 R 405955 CDS YP_853937.1 117624949 4494846 complement(3016823..3017293) 1 NC_008563.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3017293 hycI 4494846 hycI Escherichia coli APEC O1 hydrogenase 3 maturation protease YP_853937.1 3016823 R 405955 CDS YP_853938.1 117624950 4494847 complement(3017286..3017696) 1 NC_008563.1 formate hydrogenlyase maturation protein HycH 3017696 hycH 4494847 hycH Escherichia coli APEC O1 formate hydrogenlyase maturation protein HycH YP_853938.1 3017286 R 405955 CDS YP_853939.1 117624951 4494848 complement(3017693..3018460) 1 NC_008563.1 hydrogenase 3 and formate hydrogenase complex, HycG subunit 3018460 hycG 4494848 hycG Escherichia coli APEC O1 hydrogenase 3 and formate hydrogenase complex, HycG subunit YP_853939.1 3017693 R 405955 CDS YP_853940.1 117624952 4494849 complement(3018460..3019002) 1 NC_008563.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3019002 hycF 4494849 hycF Escherichia coli APEC O1 formate hydrogenlyase complex iron-sulfur subunit YP_853940.1 3018460 R 405955 CDS YP_853941.1 117624953 4494850 complement(3019012..3020721) 1 NC_008563.1 hydrogenase 3, large subunit 3020721 hycE 4494850 hycE Escherichia coli APEC O1 hydrogenase 3, large subunit YP_853941.1 3019012 R 405955 CDS YP_853942.1 117624954 4494851 complement(3020739..3021662) 1 NC_008563.1 membrane-spanning protein of formate hydrogenase 3021662 hycD 4494851 hycD Escherichia coli APEC O1 membrane-spanning protein of formate hydrogenase YP_853942.1 3020739 R 405955 CDS YP_853943.1 117624955 4494852 complement(3021665..3023491) 1 NC_008563.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3023491 hycC 4494852 hycC Escherichia coli APEC O1 formate hydrogenlyase subunit 3 YP_853943.1 3021665 R 405955 CDS YP_853944.1 117624956 4494853 complement(3023488..3024099) 1 NC_008563.1 hydrogenase 3, Fe-S subunit 3024099 hycB 4494853 hycB Escherichia coli APEC O1 hydrogenase 3, Fe-S subunit YP_853944.1 3023488 R 405955 CDS YP_853945.1 117624957 4494854 complement(3024224..3024685) 1 NC_008563.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3024685 hycA 4494854 hycA Escherichia coli APEC O1 formate hydrogenlyase regulatory protein HycA YP_853945.1 3024224 R 405955 CDS YP_853946.1 117624958 4495555 3024885..3025247 1 NC_008563.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3025247 hypA 4495555 hypA Escherichia coli APEC O1 hydrogenase nickel incorporation protein YP_853946.1 3024885 D 405955 CDS YP_853947.1 117624959 4495556 3025251..3026123 1 NC_008563.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3026123 hypB 4495556 hypB Escherichia coli APEC O1 hydrogenase nickel incorporation protein HypB YP_853947.1 3025251 D 405955 CDS YP_853948.1 117624960 4495557 3026114..3026386 1 NC_008563.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3026386 hypC 4495557 hypC Escherichia coli APEC O1 hydrogenase assembly chaperone YP_853948.1 3026114 D 405955 CDS YP_853949.1 117624961 4495558 3026386..3027507 1 NC_008563.1 hydrogenase maturation protein 3027507 hypD 4495558 hypD Escherichia coli APEC O1 hydrogenase maturation protein YP_853949.1 3026386 D 405955 CDS YP_853950.1 117624962 4495559 3027546..3028514 1 NC_008563.1 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 3028514 hypE 4495559 hypE Escherichia coli APEC O1 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein YP_853950.1 3027546 D 405955 CDS YP_853951.1 117624963 4495560 3028588..3030666 1 NC_008563.1 formate hydrogenlyase transcriptional activator 3030666 fhlA 4495560 fhlA Escherichia coli APEC O1 formate hydrogenlyase transcriptional activator YP_853951.1 3028588 D 405955 CDS YP_853952.1 117624964 4495561 3030696..3031139 1 NC_008563.1 molybdenum-pterin-binding-protein 3031139 4495561 APECO1_3793 Escherichia coli APEC O1 molybdenum-pterin-binding-protein YP_853952.1 3030696 D 405955 CDS YP_853953.1 117624965 4495562 complement(3031178..3031522) 1 NC_008563.1 hypothetical protein 3031522 ygbA 4495562 ygbA Escherichia coli APEC O1 hypothetical protein YP_853953.1 3031178 R 405955 CDS YP_853954.1 117624966 4495563 3031808..3034369 1 NC_008563.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3034369 mutS 4495563 mutS Escherichia coli APEC O1 DNA mismatch repair protein MutS YP_853954.1 3031808 D 405955 CDS YP_853955.1 117624967 4495564 3034475..3035131 1 NC_008563.1 serine/threonine-specific protein phosphatase 2 3035131 pphB 4495564 pphB Escherichia coli APEC O1 serine/threonine-specific protein phosphatase 2 YP_853955.1 3034475 D 405955 CDS YP_853956.1 117624968 4495565 complement(3035182..3035979) 1 NC_008563.1 transcriptional regulator YgbI 3035979 ygbI 4495565 ygbI Escherichia coli APEC O1 transcriptional regulator YgbI YP_853956.1 3035182 R 405955 CDS YP_853957.1 117624969 4495566 3036145..3037053 1 NC_008563.1 oxidoreductase YgbJ 3037053 ygbJ 4495566 ygbJ Escherichia coli APEC O1 oxidoreductase YgbJ YP_853957.1 3036145 D 405955 CDS YP_853958.1 117624970 4495567 3037050..3038312 1 NC_008563.1 hypothetical protein 3038312 ygbK 4495567 ygbK Escherichia coli APEC O1 hypothetical protein YP_853958.1 3037050 D 405955 CDS YP_853959.1 117624971 4495568 3038309..3038947 1 NC_008563.1 sugar aldolase; aldolase 3038947 ygbL 4495568 ygbL Escherichia coli APEC O1 aldolase YP_853959.1 3038309 D 405955 CDS YP_853960.1 117624972 4495569 3038952..3039728 1 NC_008563.1 hypothetical protein 3039728 ygbM 4495569 ygbM Escherichia coli APEC O1 hypothetical protein YP_853960.1 3038952 D 405955 CDS YP_853961.1 117624973 4495570 3039817..3041181 1 NC_008563.1 Zn-dependent hydrolase; member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3041181 ygbN 4495570 ygbN Escherichia coli APEC O1 inner membrane permease YgbN YP_853961.1 3039817 D 405955 CDS YP_853962.1 117624974 4495571 complement(3041324..3042367) 1 NC_008563.1 Zn-dependent hydrolase; hypothetical protein 3042367 4495571 APECO1_3784 Escherichia coli APEC O1 hypothetical protein YP_853962.1 3041324 R 405955 CDS YP_853963.1 117624975 4495572 3042592..3043143 1 NC_008563.1 hypothetical protein 3043143 4495572 APECO1_3783 Escherichia coli APEC O1 hypothetical protein YP_853963.1 3042592 D 405955 CDS YP_853964.1 117624976 4495573 complement(3043321..3044349) 1 NC_008563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3044349 rpoS 4495573 rpoS Escherichia coli APEC O1 RNA polymerase sigma factor RpoS YP_853964.1 3043321 R 405955 CDS YP_853965.1 117624977 4494585 complement(3044376..3045515) 1 NC_008563.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3045515 nlpD 4494585 nlpD Escherichia coli APEC O1 lipoprotein NlpD YP_853965.1 3044376 R 405955 CDS YP_853966.1 117624978 4494586 complement(3045655..3046281) 1 NC_008563.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3046281 pcm 4494586 pcm Escherichia coli APEC O1 protein-L-isoaspartate O-methyltransferase YP_853966.1 3045655 R 405955 CDS YP_853967.1 117624979 4494587 complement(3046275..3047036) 1 NC_008563.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3047036 surE 4494587 surE Escherichia coli APEC O1 stationary phase survival protein SurE YP_853967.1 3046275 R 405955 CDS YP_853968.1 117624980 4494588 complement(3047017..3048066) 1 NC_008563.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3048066 truD 4494588 truD Escherichia coli APEC O1 tRNA pseudouridine synthase D YP_853968.1 3047017 R 405955 CDS YP_853969.1 117624981 4494589 complement(3048063..3048542) 1 NC_008563.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3048542 ispF 4494589 ispF Escherichia coli APEC O1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_853969.1 3048063 R 405955 CDS YP_853970.1 117624982 4494590 complement(3048542..3049252) 1 NC_008563.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3049252 ispD 4494590 ispD Escherichia coli APEC O1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_853970.1 3048542 R 405955 CDS YP_853971.1 117624983 4494591 complement(3049271..3049582) 1 NC_008563.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3049582 ftsB 4494591 ftsB Escherichia coli APEC O1 cell division protein FtsB YP_853971.1 3049271 R 405955 CDS YP_853972.1 117624984 4494592 complement(3049775..3050098) 1 NC_008563.1 hypothetical protein 3050098 ygbE 4494592 ygbE Escherichia coli APEC O1 hypothetical protein YP_853972.1 3049775 R 405955 CDS YP_853973.1 117624985 4494593 complement(3050148..3050753) 1 NC_008563.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3050753 cysC 4494593 cysC Escherichia coli APEC O1 adenylylsulfate kinase YP_853973.1 3050148 R 405955 CDS YP_853974.1 117624986 4494594 complement(3050753..3052180) 1 NC_008563.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3052180 cysN 4494594 cysN Escherichia coli APEC O1 sulfate adenylyltransferase subunit 1 YP_853974.1 3050753 R 405955 CDS YP_853975.1 117624987 4494595 complement(3052182..3053090) 1 NC_008563.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3053090 cysD 4494595 cysD Escherichia coli APEC O1 sulfate adenylyltransferase subunit 2 YP_853975.1 3052182 R 405955 CDS YP_853976.1 117624988 4494596 3053342..3054379 1 NC_008563.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 3054379 iap 4494596 iap Escherichia coli APEC O1 alkaline phosphatase isozyme conversion aminopeptidase YP_853976.1 3053342 D 405955 CDS YP_853977.1 117624989 4494597 complement(3054921..3055655) 1 NC_008563.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3055655 cysH 4494597 cysH Escherichia coli APEC O1 phosphoadenosine phosphosulfate reductase YP_853977.1 3054921 R 405955 CDS YP_853978.1 117624990 4494598 complement(3055729..3057441) 1 NC_008563.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3057441 cysI 4494598 cysI Escherichia coli APEC O1 sulfite reductase subunit beta YP_853978.1 3055729 R 405955 CDS YP_853979.1 117624991 4494599 complement(3057441..3059240) 1 NC_008563.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3059240 cysJ 4494599 cysJ Escherichia coli APEC O1 sulfite reductase subunit alpha YP_853979.1 3057441 R 405955 CDS YP_853980.1 117624992 4494600 3059556..3059921 1 NC_008563.1 6-pyruvoyl tetrahydrobiopterin synthase 3059921 ygcM 4494600 ygcM Escherichia coli APEC O1 6-pyruvoyl tetrahydrobiopterin synthase YP_853980.1 3059556 D 405955 CDS YP_853981.1 117624993 4494601 3059999..3061270 1 NC_008563.1 electron transfer flavoprotein-quinone oxidoreductase YgcN 3061270 ygcN 4494601 ygcN Escherichia coli APEC O1 electron transfer flavoprotein-quinone oxidoreductase YgcN YP_853981.1 3059999 D 405955 CDS YP_853982.1 117624994 4494602 3061225..3061521 1 NC_008563.1 ferredoxin-like protein YgcO 3061521 ygcO 4494602 ygcO Escherichia coli APEC O1 ferredoxin-like protein YgcO YP_853982.1 3061225 D 405955 CDS YP_853983.1 117624995 4492406 3061538..3062113 1 NC_008563.1 anti-terminator regulatory protein 3062113 4492406 APECO1_3764 Escherichia coli APEC O1 anti-terminator regulatory protein YP_853983.1 3061538 D 405955 CDS YP_853984.1 117624996 4492407 complement(3062261..3063154) 1 NC_008563.1 electron transfer flavoprotein subunit YgcQ 3063154 ygcQ 4492407 ygcQ Escherichia coli APEC O1 electron transfer flavoprotein subunit YgcQ YP_853984.1 3062261 R 405955 CDS YP_853985.1 117624997 4492408 complement(3063118..3063912) 1 NC_008563.1 electron transfer flavoprotein subunit YgcR 3063912 ygcR 4492408 ygcR Escherichia coli APEC O1 electron transfer flavoprotein subunit YgcR YP_853985.1 3063118 R 405955 CDS YP_853986.1 117624998 4492409 complement(3063875..3065212) 1 NC_008563.1 metabolite transport protein YgcS 3065212 ygcS 4492409 ygcS Escherichia coli APEC O1 metabolite transport protein YgcS YP_853986.1 3063875 R 405955 CDS YP_853987.1 117624999 4492410 complement(3065234..3066688) 1 NC_008563.1 FAD containing dehydrogenase 3066688 ygcU 4492410 ygcU Escherichia coli APEC O1 FAD containing dehydrogenase YP_853987.1 3065234 R 405955 CDS YP_853988.1 117625000 4492411 complement(3066758..3067618) 1 NC_008563.1 oxidoreductase YgcW 3067618 ygcW 4492411 ygcW Escherichia coli APEC O1 oxidoreductase YgcW YP_853988.1 3066758 R 405955 CDS YP_853989.1 117625001 4492412 3067862..3069139 1 NC_008563.1 transporter 3069139 yqcE 4492412 yqcE Escherichia coli APEC O1 transporter YP_853989.1 3067862 D 405955 CDS YP_853990.1 117625002 4492413 3069166..3070644 1 NC_008563.1 sugar kinase 3070644 ygcE 4492413 ygcE Escherichia coli APEC O1 sugar kinase YP_853990.1 3069166 D 405955 CDS YP_853991.1 117625003 4492414 complement(3071118..3071789) 1 NC_008563.1 hypothetical protein 3071789 4492414 APECO1_3756 Escherichia coli APEC O1 hypothetical protein YP_853991.1 3071118 R 405955 CDS YP_853992.1 117625004 4492415 3071962..3072576 1 NC_008563.1 hypothetical protein 3072576 4492415 APECO1_3755 Escherichia coli APEC O1 hypothetical protein YP_853992.1 3071962 D 405955 CDS YP_853993.1 117625005 4492416 3072560..3073426 1 NC_008563.1 hypothetical protein 3073426 4492416 APECO1_3754 Escherichia coli APEC O1 hypothetical protein YP_853993.1 3072560 D 405955 CDS YP_853994.1 117625006 4492417 3073499..3074647 1 NC_008563.1 hypothetical protein 3074647 4492417 APECO1_3753 Escherichia coli APEC O1 hypothetical protein YP_853994.1 3073499 D 405955 CDS YP_853995.1 117625007 4492418 3074653..3075546 1 NC_008563.1 hypothetical protein 3075546 4492418 APECO1_3752 Escherichia coli APEC O1 hypothetical protein YP_853995.1 3074653 D 405955 CDS YP_853996.1 117625008 4492419 complement(3075606..3076904) 1 NC_008563.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3076904 eno 4492419 eno Escherichia coli APEC O1 phosphopyruvate hydratase YP_853996.1 3075606 R 405955 CDS YP_853997.1 117625009 4492420 complement(3076992..3078629) 1 NC_008563.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3078629 pyrG 4492420 pyrG Escherichia coli APEC O1 CTP synthetase YP_853997.1 3076992 R 405955 CDS YP_853998.1 117625010 4492421 complement(3078857..3079648) 1 NC_008563.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3079648 mazG 4492421 mazG Escherichia coli APEC O1 nucleoside triphosphate pyrophosphohydrolase YP_853998.1 3078857 R 405955 CDS YP_853999.1 117625011 4492422 complement(3079720..3080055) 1 NC_008563.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 3080055 chpA 4492422 chpA Escherichia coli APEC O1 toxin ChpA YP_853999.1 3079720 R 405955 CDS YP_854000.1 117625012 4492423 complement(3080381..3082615) 1 NC_008563.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3082615 relA 4492423 relA Escherichia coli APEC O1 GDP/GTP pyrophosphokinase YP_854000.1 3080381 R 405955 CDS YP_854001.1 117625013 4494409 complement(3082663..3083964) 1 NC_008563.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3083964 rumA 4494409 rumA Escherichia coli APEC O1 23S rRNA 5-methyluridine methyltransferase YP_854001.1 3082663 R 405955 CDS YP_854002.1 117625014 4494410 3084021..3086777 1 NC_008563.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3086777 barA 4494410 barA Escherichia coli APEC O1 hybrid sensory histidine kinase BarA YP_854002.1 3084021 D 405955 CDS YP_854003.1 117625015 4494411 complement(3087008..3088348) 1 NC_008563.1 glucarate dehydratase 3088348 gudD 4494411 gudD Escherichia coli APEC O1 glucarate dehydratase YP_854003.1 3087008 R 405955 CDS YP_854004.1 117625016 4494412 complement(3088369..3089709) 1 NC_008563.1 glucarate dehydratase 3089709 ygcY 4494412 ygcY Escherichia coli APEC O1 glucarate dehydratase YP_854004.1 3088369 R 405955 CDS YP_854005.1 117625017 4494413 complement(3089711..3091063) 1 NC_008563.1 D-glucarate transporter 3091063 gudP 4494413 gudP Escherichia coli APEC O1 D-glucarate transporter YP_854005.1 3089711 R 405955 CDS YP_854006.1 117625018 4494414 complement(3091497..3091946) 1 NC_008563.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3091946 yqcA 4494414 yqcA Escherichia coli APEC O1 flavodoxin YP_854006.1 3091497 R 405955 CDS YP_854007.1 117625019 4494415 complement(3091964..3092746) 1 NC_008563.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3092746 yqcB 4494415 yqcB Escherichia coli APEC O1 tRNA pseudouridine synthase C YP_854007.1 3091964 R 405955 CDS YP_854008.1 117625020 4494416 complement(3092746..3093075) 1 NC_008563.1 hypothetical protein 3093075 yqcC 4494416 yqcC Escherichia coli APEC O1 hypothetical protein YP_854008.1 3092746 R 405955 CDS YP_854009.1 117625021 4494417 complement(3093697..3093978) 1 NC_008563.1 SecY interacting protein Syd 3093978 syd 4494417 syd Escherichia coli APEC O1 SecY interacting protein Syd YP_854009.1 3093697 R 405955 CDS YP_854010.1 117625022 4494418 3094310..3095158 1 NC_008563.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3095158 queF 4494418 queF Escherichia coli APEC O1 7-cyano-7-deazaguanine reductase YP_854010.1 3094310 D 405955 CDS YP_854011.1 117625023 4494419 3095300..3096634 1 NC_008563.1 hypothetical protein 3096634 ygdH 4494419 ygdH Escherichia coli APEC O1 hypothetical protein YP_854011.1 3095300 D 405955 CDS YP_854012.1 117625024 4494420 3097191..3098480 1 NC_008563.1 serine transporter 3098480 sdaC 4494420 sdaC Escherichia coli APEC O1 serine transporter YP_854012.1 3097191 D 405955 CDS YP_854013.1 117625025 4494421 3098538..3099905 1 NC_008563.1 L-serine deaminase II 3099905 sdaB 4494421 sdaB Escherichia coli APEC O1 L-serine deaminase II YP_854013.1 3098538 D 405955 CDS YP_854014.1 117625026 4494422 3100128..3100772 1 NC_008563.1 exodeoxyribonuclease IX 3100772 exo 4494422 exo Escherichia coli APEC O1 exodeoxyribonuclease IX YP_854014.1 3100128 D 405955 CDS YP_854015.1 117625027 4494423 complement(3100877..3102028) 1 NC_008563.1 L-1,2-propanediol oxidoreductase 3102028 fucO 4494423 fucO Escherichia coli APEC O1 L-1,2-propanediol oxidoreductase YP_854015.1 3100877 R 405955 CDS YP_854016.1 117625028 4494424 complement(3102053..3102700) 1 NC_008563.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3102700 fucA 4494424 fucA Escherichia coli APEC O1 L-fuculose phosphate aldolase YP_854016.1 3102053 R 405955 CDS YP_854017.1 117625029 4494425 3103247..3104563 1 NC_008563.1 L-fucose transporter 3104563 fucP 4494425 fucP Escherichia coli APEC O1 L-fucose transporter YP_854017.1 3103247 D 405955 CDS YP_854018.1 117625030 4494426 3104596..3106371 1 NC_008563.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3106371 fucI 4494426 fucI Escherichia coli APEC O1 L-fucose isomerase YP_854018.1 3104596 D 405955 CDS YP_854019.1 117625031 4494427 3106450..3107898 1 NC_008563.1 L-fuculokinase 3107898 fucK 4494427 fucK Escherichia coli APEC O1 L-fuculokinase YP_854019.1 3106450 D 405955 CDS YP_854020.1 117625032 4491753 3107900..3108322 1 NC_008563.1 L-fucose mutarotase 3108322 fucU 4491753 fucU Escherichia coli APEC O1 L-fucose mutarotase YP_854020.1 3107900 D 405955 CDS YP_854021.1 117625033 4491754 3108371..3109111 1 NC_008563.1 regulates expression of genes involved in L-fucose utilization; FucR family transcriptional regulator 3109111 fucR 4491754 fucR Escherichia coli APEC O1 FucR family transcriptional regulator YP_854021.1 3108371 D 405955 CDS YP_854022.1 117625034 4491755 complement(3109155..3110255) 1 NC_008563.1 RNA 2'-O-ribose methyltransferase 3110255 ygdE 4491755 ygdE Escherichia coli APEC O1 RNA 2'-O-ribose methyltransferase YP_854022.1 3109155 R 405955 CDS YP_854023.1 117625035 4491756 complement(3110248..3110643) 1 NC_008563.1 hypothetical protein 3110643 4491756 APECO1_3724 Escherichia coli APEC O1 hypothetical protein YP_854023.1 3110248 R 405955 CDS YP_854024.1 117625036 4491757 complement(3110662..3111579) 1 NC_008563.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3111579 gcvA 4491757 gcvA Escherichia coli APEC O1 DNA-binding transcriptional activator GcvA YP_854024.1 3110662 R 405955 CDS YP_854025.1 117625037 4491758 3112349..3113554 1 NC_008563.1 cysteine sulfinate desulfinase 3113554 csdA 4491758 csdA Escherichia coli APEC O1 cysteine sulfinate desulfinase YP_854025.1 3112349 D 405955 CDS YP_854026.1 117625038 4491759 3113554..3113997 1 NC_008563.1 Fe-S metabolism protein 3113997 ygdK 4491759 ygdK Escherichia coli APEC O1 Fe-S metabolism protein YP_854026.1 3113554 D 405955 CDS YP_854027.1 117625039 4491760 complement(3114048..3114854) 1 NC_008563.1 hypothetical protein 3114854 ygdL 4491760 ygdL Escherichia coli APEC O1 hypothetical protein YP_854027.1 3114048 R 405955 CDS YP_854028.2 162317572 4491761 complement(3114931..3116028) 1 NC_008563.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3116028 mltA 4491761 mltA Escherichia coli APEC O1 murein transglycosylase A YP_854028.2 3114931 R 405955 CDS YP_854029.1 117625041 4491762 3117169..3117669 1 NC_008563.1 hypothetical protein 3117669 4491762 APECO1_3718 Escherichia coli APEC O1 hypothetical protein YP_854029.1 3117169 D 405955 CDS YP_854030.1 117625042 4491763 3117722..3119266 1 NC_008563.1 hypothetical protein 3119266 4491763 APECO1_3717 Escherichia coli APEC O1 hypothetical protein YP_854030.1 3117722 D 405955 CDS YP_854031.1 117625043 4491764 3119284..3120621 1 NC_008563.1 hypothetical protein 3120621 4491764 APECO1_3716 Escherichia coli APEC O1 hypothetical protein YP_854031.1 3119284 D 405955 CDS YP_854032.1 117625044 4491765 3120618..3121283 1 NC_008563.1 hypothetical protein 3121283 4491765 APECO1_3715 Escherichia coli APEC O1 hypothetical protein YP_854032.1 3120618 D 405955 CDS YP_854033.1 117625045 4491766 3121335..3122948 1 NC_008563.1 outer membrane protein 3122948 4491766 APECO1_3714 Escherichia coli APEC O1 outer membrane protein YP_854033.1 3121335 D 405955 CDS YP_854034.1 117625046 4491767 3123006..3123497 1 NC_008563.1 hemolysin-coregulated protein 3123497 4491767 APECO1_3713 Escherichia coli APEC O1 hemolysin-coregulated protein YP_854034.1 3123006 D 405955 CDS YP_854035.1 117625047 4491768 3123689..3126334 1 NC_008563.1 ATPase 3126334 4491768 APECO1_3712 Escherichia coli APEC O1 ATPase YP_854035.1 3123689 D 405955 CDS YP_854036.1 117625048 4491769 3126346..3128826 1 NC_008563.1 hypothetical protein 3128826 4491769 APECO1_3711 Escherichia coli APEC O1 hypothetical protein YP_854036.1 3126346 D 405955 CDS YP_854037.1 117625049 4491770 3128846..3130012 1 NC_008563.1 hypothetical protein 3130012 4491770 APECO1_3710 Escherichia coli APEC O1 hypothetical protein YP_854037.1 3128846 D 405955 CDS YP_854038.1 117625050 4491771 3130225..3130605 1 NC_008563.1 hypothetical protein 3130605 4491771 APECO1_3709 Escherichia coli APEC O1 hypothetical protein YP_854038.1 3130225 D 405955 CDS YP_854039.1 117625051 4495613 3130580..3131413 1 NC_008563.1 hypothetical protein 3131413 4495613 APECO1_3708 Escherichia coli APEC O1 hypothetical protein YP_854039.1 3130580 D 405955 CDS YP_854040.1 117625052 4495614 3131382..3131675 1 NC_008563.1 hypothetical protein 3131675 4495614 APECO1_3707 Escherichia coli APEC O1 hypothetical protein YP_854040.1 3131382 D 405955 CDS YP_854041.1 117625053 4495615 3133547..3136885 1 NC_008563.1 hypothetical protein 3136885 4495615 APECO1_3705 Escherichia coli APEC O1 hypothetical protein YP_854041.1 3133547 D 405955 CDS YP_854042.1 117625054 4495616 complement(3136943..3137692) 1 NC_008563.1 ISEc12 ATP-binding protein 3137692 4495616 APECO1_3704 Escherichia coli APEC O1 ISEc12 ATP-binding protein YP_854042.1 3136943 R 405955 CDS YP_854043.1 117625055 4495617 complement(3137704..3139245) 1 NC_008563.1 transposase for ISEc12 3139245 4495617 APECO1_3703 Escherichia coli APEC O1 transposase for ISEc12 YP_854043.1 3137704 R 405955 CDS YP_854044.1 117625056 4495618 3139452..3141089 1 NC_008563.1 hypothetical protein 3141089 4495618 APECO1_3702 Escherichia coli APEC O1 hypothetical protein YP_854044.1 3139452 D 405955 CDS YP_854045.1 117625057 4495619 3141089..3142672 1 NC_008563.1 hypothetical protein 3142672 4495619 APECO1_3701 Escherichia coli APEC O1 hypothetical protein YP_854045.1 3141089 D 405955 CDS YP_854046.1 117625058 4495620 3142672..3143301 1 NC_008563.1 hypothetical protein 3143301 4495620 APECO1_3700 Escherichia coli APEC O1 hypothetical protein YP_854046.1 3142672 D 405955 CDS YP_854047.1 117625059 4495621 3143558..3144001 1 NC_008563.1 hypothetical protein 3144001 4495621 APECO1_3699 Escherichia coli APEC O1 hypothetical protein YP_854047.1 3143558 D 405955 CDS YP_854048.1 117625060 4495622 3144371..3146131 1 NC_008563.1 hypothetical protein 3146131 4495622 APECO1_3698 Escherichia coli APEC O1 hypothetical protein YP_854048.1 3144371 D 405955 CDS YP_854049.1 117625061 4495623 3146095..3147174 1 NC_008563.1 hypothetical protein 3147174 4495623 APECO1_3697 Escherichia coli APEC O1 hypothetical protein YP_854049.1 3146095 D 405955 CDS YP_854050.1 117625062 4495624 3147155..3147691 1 NC_008563.1 hypothetical protein 3147691 4495624 APECO1_3696 Escherichia coli APEC O1 hypothetical protein YP_854050.1 3147155 D 405955 CDS YP_854051.1 117625063 4495625 3147695..3148123 1 NC_008563.1 hypothetical protein 3148123 4495625 APECO1_3695 Escherichia coli APEC O1 hypothetical protein YP_854051.1 3147695 D 405955 CDS YP_854052.1 117625064 4495626 3148123..3149499 1 NC_008563.1 hypothetical protein 3149499 4495626 APECO1_3694 Escherichia coli APEC O1 hypothetical protein YP_854052.1 3148123 D 405955 CDS YP_854053.1 117625065 4495627 complement(3149801..3150748) 1 NC_008563.1 2-hydroxyacid dehydrogenase 3150748 4495627 APECO1_3693 Escherichia coli APEC O1 2-hydroxyacid dehydrogenase YP_854053.1 3149801 R 405955 CDS YP_854054.1 117625066 4495628 complement(3150820..3151416) 1 NC_008563.1 phosphosugar isomerase 3151416 4495628 APECO1_3692 Escherichia coli APEC O1 phosphosugar isomerase YP_854054.1 3150820 R 405955 CDS YP_854055.1 117625067 4495629 complement(3151419..3152594) 1 NC_008563.1 aminotransferase 3152594 4495629 APECO1_3691 Escherichia coli APEC O1 aminotransferase YP_854055.1 3151419 R 405955 CDS YP_854056.1 117625068 4495630 complement(3152594..3154174) 1 NC_008563.1 PTS system, maltose and glucose-specific IIABC component 3154174 4495630 APECO1_3690 Escherichia coli APEC O1 PTS system, maltose and glucose-specific IIABC component YP_854056.1 3152594 R 405955 CDS YP_854057.1 117625069 4495631 complement(3154206..3155087) 1 NC_008563.1 antiterminator 3155087 4495631 APECO1_3689 Escherichia coli APEC O1 antiterminator YP_854057.1 3154206 R 405955 CDS YP_854058.1 117625070 4495632 complement(3155288..3156631) 1 NC_008563.1 N-acetylmuramoyl-L-alanine amidase 3156631 amiC 4495632 amiC Escherichia coli APEC O1 N-acetylmuramoyl-L-alanine amidase YP_854058.1 3155288 R 405955 CDS YP_854059.1 117625071 4492240 3156863..3158104 1 NC_008563.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3158104 argA 4492240 argA Escherichia coli APEC O1 N-acetylglutamate synthase YP_854059.1 3156863 D 405955 CDS YP_854060.1 117625072 4492241 complement(3158166..3159992) 1 NC_008563.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3159992 recD 4492241 recD Escherichia coli APEC O1 exonuclease V subunit alpha YP_854060.1 3158166 R 405955 CDS YP_854061.1 117625073 4492242 complement(3159992..3163534) 1 NC_008563.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3163534 recB 4492242 recB Escherichia coli APEC O1 exonuclease V subunit beta YP_854061.1 3159992 R 405955 CDS YP_854062.1 117625074 4492243 complement(3163527..3166415) 1 NC_008563.1 protease III 3166415 ptrA 4492243 ptrA Escherichia coli APEC O1 protease III YP_854062.1 3163527 R 405955 CDS YP_854063.1 117625075 4492244 complement(3166591..3169959) 1 NC_008563.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3169959 recC 4492244 recC Escherichia coli APEC O1 exonuclease V subunit gamma YP_854063.1 3166591 R 405955 CDS YP_854064.1 117625076 4492245 complement(3169972..3170295) 1 NC_008563.1 hypothetical protein 3170295 ppdC 4492245 ppdC Escherichia coli APEC O1 hypothetical protein YP_854064.1 3169972 R 405955 CDS YP_854065.1 117625077 4492246 complement(3170280..3170645) 1 NC_008563.1 hypothetical protein 3170645 ygdB 4492246 ygdB Escherichia coli APEC O1 hypothetical protein YP_854065.1 3170280 R 405955 CDS YP_854066.1 117625078 4492247 complement(3170684..3171487) 1 NC_008563.1 hypothetical protein 3171487 ppdB 4492247 ppdB Escherichia coli APEC O1 hypothetical protein YP_854066.1 3170684 R 405955 CDS YP_854067.1 117625079 4492248 complement(3171238..3171708) 1 NC_008563.1 type II secretory pathway, pseudopilin; hypothetical protein 3171708 ppdA 4492248 ppdA Escherichia coli APEC O1 hypothetical protein YP_854067.1 3171238 R 405955 CDS YP_854068.1 117625080 4492249 complement(3171893..3172687) 1 NC_008563.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3172687 thyA 4492249 thyA Escherichia coli APEC O1 thymidylate synthase YP_854068.1 3171893 R 405955 CDS YP_854069.1 117625081 4492250 complement(3172694..3173569) 1 NC_008563.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3173569 lgt 4492250 lgt Escherichia coli APEC O1 prolipoprotein diacylglyceryl transferase YP_854069.1 3172694 R 405955 CDS YP_854070.1 117625082 4492251 complement(3173720..3175966) 1 NC_008563.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3175966 ptsP 4492251 ptsP Escherichia coli APEC O1 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_854070.1 3173720 R 405955 CDS YP_854071.1 117625083 4492252 complement(3175979..3176443) 1 NC_008563.1 dinucleoside polyphosphate hydrolase 3176443 ygdP 4492252 ygdP Escherichia coli APEC O1 dinucleoside polyphosphate hydrolase YP_854071.1 3175979 R 405955 CDS YP_854072.1 117625084 4492253 3177194..3177883 1 NC_008563.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3177883 mutH 4492253 mutH Escherichia coli APEC O1 DNA mismatch repair protein YP_854072.1 3177194 D 405955 CDS YP_854073.1 117625085 4492254 3177952..3178665 1 NC_008563.1 possibly involved in tellurite resistance; integral membrane protein TerC 3178665 terC 4492254 terC Escherichia coli APEC O1 integral membrane protein TerC YP_854073.1 3177952 D 405955 CDS YP_854074.1 117625086 4492255 3179129..3180169 1 NC_008563.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3180169 tas 4492255 tas Escherichia coli APEC O1 aldo-keto reductase YP_854074.1 3179129 D 405955 CDS YP_854075.1 117625087 4492256 complement(3180201..3181394) 1 NC_008563.1 lysophospholipid transporter LplT 3181394 ygeD 4492256 ygeD Escherichia coli APEC O1 lysophospholipid transporter LplT YP_854075.1 3180201 R 405955 CDS YP_854076.1 117625088 4492257 complement(3181387..3183546) 1 NC_008563.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3183546 aas 4492257 aas Escherichia coli APEC O1 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_854076.1 3181387 R 405955 CDS YP_854077.1 117625089 4492258 3184132..3185163 1 NC_008563.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3185163 galR 4492258 galR Escherichia coli APEC O1 DNA-binding transcriptional regulator GalR YP_854077.1 3184132 D 405955 CDS YP_854078.1 117625090 4491518 complement(3185170..3186432) 1 NC_008563.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3186432 lysA 4491518 lysA Escherichia coli APEC O1 diaminopimelate decarboxylase YP_854078.1 3185170 R 405955 CDS YP_854079.1 117625091 4491519 3186554..3187489 1 NC_008563.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3187489 lysR 4491519 lysR Escherichia coli APEC O1 LysR family transcriptional regulator YP_854079.1 3186554 D 405955 CDS YP_854080.1 117625092 4491520 complement(3187476..3188168) 1 NC_008563.1 Asp/Glu/Hydantoin racemase family; racemase 3188168 ygeA 4491520 ygeA Escherichia coli APEC O1 racemase YP_854080.1 3187476 R 405955 CDS YP_854081.1 117625093 4491521 complement(3188297..3189715) 1 NC_008563.1 arabinose transporter 3189715 araE 4491521 araE Escherichia coli APEC O1 arabinose transporter YP_854081.1 3188297 R 405955 CDS YP_854082.1 117625094 4491522 complement(3190030..3190791) 1 NC_008563.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3190791 kduD 4491522 kduD Escherichia coli APEC O1 2-deoxy-D-gluconate 3-dehydrogenase YP_854082.1 3190030 R 405955 CDS YP_854083.1 117625095 4491523 complement(3190821..3191549) 1 NC_008563.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3191549 kduI 4491523 kduI Escherichia coli APEC O1 5-keto-4-deoxyuronate isomerase YP_854083.1 3190821 R 405955 CDS YP_854084.1 117625096 4491524 complement(3191944..3193125) 1 NC_008563.1 thiolase domain; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3193125 yqeF 4491524 yqeF Escherichia coli APEC O1 acetyl-CoA acetyltransferase YP_854084.1 3191944 R 405955 CDS YP_854085.1 117625097 4491525 3193380..3194609 1 NC_008563.1 transporter 3194609 yqeG 4491525 yqeG Escherichia coli APEC O1 transporter YP_854085.1 3193380 D 405955 CDS YP_854086.1 117625098 4491526 complement(3195078..3195791) 1 NC_008563.1 lipoportein 3195791 ygeR 4491526 ygeR Escherichia coli APEC O1 lipoportein YP_854086.1 3195078 R 405955 CDS YP_854087.1 117625099 4491527 3196247..3198544 1 NC_008563.1 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3198544 4491527 APECO1_3659 Escherichia coli APEC O1 xanthine dehydrogenase subunit XdhA YP_854087.1 3196247 D 405955 CDS YP_854088.1 117625100 4491528 3198555..3199433 1 NC_008563.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3199433 ygeT 4491528 ygeT Escherichia coli APEC O1 xanthine dehydrogenase subunit XdhB YP_854088.1 3198555 D 405955 CDS YP_854089.1 117625101 4491529 complement(3199949..3201727) 1 NC_008563.1 regulatory protein; DNA-binding transcriptional regulator 3201727 ygeV 4491529 ygeV Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_854089.1 3199949 R 405955 CDS YP_854090.1 117625102 4491530 3202203..3203393 1 NC_008563.1 aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase family protein 3203393 ygeW 4491530 ygeW Escherichia coli APEC O1 aspartate/ornithine carbamoyltransferase family protein YP_854090.1 3202203 D 405955 CDS YP_854091.1 117625103 4491531 3203451..3204647 1 NC_008563.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3204647 ygeX 4491531 ygeX Escherichia coli APEC O1 diaminopropionate ammonia-lyase YP_854091.1 3203451 D 405955 CDS YP_854092.1 117625104 4491532 3204705..3205916 1 NC_008563.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3205916 ygeY 4491532 ygeY Escherichia coli APEC O1 peptidase YP_854092.1 3204705 D 405955 CDS YP_854093.1 117625105 4491533 3205969..3207354 1 NC_008563.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3207354 ygeZ 4491533 ygeZ Escherichia coli APEC O1 phenylhydantoinase YP_854093.1 3205969 D 405955 CDS YP_854094.1 117625106 4491534 3207402..3208334 1 NC_008563.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3208334 yqeA 4491534 yqeA Escherichia coli APEC O1 carbamate kinase YP_854094.1 3207402 D 405955 CDS YP_854095.1 117625107 4491535 complement(3208375..3210000) 1 NC_008563.1 synthase 3210000 yqeB 4491535 yqeB Escherichia coli APEC O1 synthase YP_854095.1 3208375 R 405955 CDS YP_854096.1 117625108 4491536 complement(3210048..3210650) 1 NC_008563.1 hypothetical protein 3210650 yqeC 4491536 yqeC Escherichia coli APEC O1 hypothetical protein YP_854096.1 3210048 R 405955 CDS YP_854097.1 117625109 4491537 3210922..3211500 1 NC_008563.1 hypothetical protein 3211500 ygfJ 4491537 ygfJ Escherichia coli APEC O1 hypothetical protein YP_854097.1 3210922 D 405955 CDS YP_854098.1 117625110 4494913 3211822..3214920 1 NC_008563.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3214920 ygfK 4494913 ygfK Escherichia coli APEC O1 selenate reductase subunit YgfK YP_854098.1 3211822 D 405955 CDS YP_854099.1 117625111 4494914 3214923..3216251 1 NC_008563.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3216251 ssnA 4494914 ssnA Escherichia coli APEC O1 chlorohydrolase/aminohydrolase YP_854099.1 3214923 D 405955 CDS YP_854100.1 117625112 4494915 3216302..3217081 1 NC_008563.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3217081 ygfM 4494915 ygfM Escherichia coli APEC O1 selenate reductase subunit YgfM YP_854100.1 3216302 D 405955 CDS YP_854101.1 117625113 4494916 3217078..3219948 1 NC_008563.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3219948 xdhD 4494916 xdhD Escherichia coli APEC O1 selenate reductase subunit YgfN YP_854101.1 3217078 D 405955 CDS YP_854102.1 117625114 4494917 3220113..3221513 1 NC_008563.1 transporter 3221513 ygfO 4494917 ygfO Escherichia coli APEC O1 transporter YP_854102.1 3220113 D 405955 CDS YP_854103.1 117625115 4494918 3221528..3222847 1 NC_008563.1 Catalyzes the deamination of guanine; guanine deaminase 3222847 ygfP 4494918 ygfP Escherichia coli APEC O1 guanine deaminase YP_854103.1 3221528 D 405955 CDS YP_854104.1 117625116 4494919 3222883..3224250 1 NC_008563.1 transporter 3224250 ygfQ 4494919 ygfQ Escherichia coli APEC O1 transporter YP_854104.1 3222883 D 405955 CDS YP_854105.1 117625117 4494920 complement(3224286..3224774) 1 NC_008563.1 oxidoreductase, 4Fe-4S ferredoxin-type subunit 3224774 ygfS 4494920 ygfS Escherichia coli APEC O1 oxidoreductase, 4Fe-4S ferredoxin-type subunit YP_854105.1 3224286 R 405955 CDS YP_854106.1 117625118 4494921 complement(3224774..3226708) 1 NC_008563.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3226708 ygfT 4494921 ygfT Escherichia coli APEC O1 oxidoreductase Fe-S binding subunit YP_854106.1 3224774 R 405955 CDS YP_854107.1 117625119 4494922 3227060..3228577 1 NC_008563.1 purine permease YgfU 3228577 ygfU 4494922 ygfU Escherichia coli APEC O1 purine permease YgfU YP_854107.1 3227060 D 405955 CDS YP_854108.1 117625120 4494923 3228827..3229375 1 NC_008563.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3229375 4494923 APECO1_3638 Escherichia coli APEC O1 isopentenyl-diphosphate delta-isomerase YP_854108.1 3228827 D 405955 CDS YP_854109.1 117625121 4494924 complement(3229418..3230935) 1 NC_008563.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3230935 lysS 4494924 lysS Escherichia coli APEC O1 lysyl-tRNA synthetase YP_854109.1 3229418 R 405955 CDS YP_854110.1 117625122 4494925 complement(3230945..3231826) 1 NC_008563.1 peptide chain release factor 2 3231826 prfB 4494925 prfB Escherichia coli APEC O1 peptide chain release factor 2 YP_854110.1 3230945 R 405955 CDS YP_854111.1 117625123 4494926 complement(3232134..3233726) 1 NC_008563.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3233726 4494926 APECO1_3635 Escherichia coli APEC O1 ssDNA exonuclease RecJ YP_854111.1 3232134 R 405955 CDS YP_854112.1 117625124 4494927 complement(3233873..3234583) 1 NC_008563.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3234583 dsbC 4494927 dsbC Escherichia coli APEC O1 thiol:disulfide interchange protein DsbC YP_854112.1 3233873 R 405955 CDS YP_854113.1 117625125 4494928 complement(3234608..3235402) 1 NC_008563.1 site-specific tyrosine recombinase XerD 3235402 xerD 4494928 xerD Escherichia coli APEC O1 site-specific tyrosine recombinase XerD YP_854113.1 3234608 R 405955 CDS YP_854114.1 117625126 4494929 3235616..3236137 1 NC_008563.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3236137 fldB 4494929 fldB Escherichia coli APEC O1 flavodoxin FldB YP_854114.1 3235616 D 405955 CDS YP_854115.1 117625127 4494930 complement(3236177..3236491) 1 NC_008563.1 hypothetical protein 3236491 4494930 APECO1_3631 Escherichia coli APEC O1 hypothetical protein YP_854115.1 3236177 R 405955 CDS YP_854116.1 117625128 4494931 complement(3236565..3236831) 1 NC_008563.1 hypothetical protein 3236831 4494931 APECO1_3630 Escherichia coli APEC O1 hypothetical protein YP_854116.1 3236565 R 405955 CDS YP_854117.1 117625129 4493126 3237074..3238054 1 NC_008563.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3238054 ygfZ 4493126 ygfZ Escherichia coli APEC O1 global regulator YP_854117.1 3237074 D 405955 CDS YP_854118.1 117625130 4493127 complement(3238131..3238790) 1 NC_008563.1 oxidoreductase, inner membrane subunit 3238790 yqfA 4493127 yqfA Escherichia coli APEC O1 oxidoreductase, inner membrane subunit YP_854118.1 3238131 R 405955 CDS YP_854119.1 117625131 4493128 complement(3238954..3239265) 1 NC_008563.1 hypothetical protein 3239265 4493128 APECO1_3627 Escherichia coli APEC O1 hypothetical protein YP_854119.1 3238954 R 405955 CDS YP_854120.1 117625132 4493129 3239304..3240743 1 NC_008563.1 6-phospho-beta-glucosidase 3240743 bglA 4493129 bglA Escherichia coli APEC O1 6-phospho-beta-glucosidase YP_854120.1 3239304 D 405955 CDS YP_854121.1 117625133 4493130 complement(3240909..3243782) 1 NC_008563.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3243782 gcvP 4493130 gcvP Escherichia coli APEC O1 glycine dehydrogenase YP_854121.1 3240909 R 405955 CDS YP_854122.1 117625134 4493131 complement(3243900..3244289) 1 NC_008563.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3244289 gcvH 4493131 gcvH Escherichia coli APEC O1 glycine cleavage system protein H YP_854122.1 3243900 R 405955 CDS YP_854123.2 229775962 4493132 complement(3244313..3245407) 1 NC_008563.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3245407 gcvT 4493132 gcvT Escherichia coli APEC O1 glycine cleavage system aminomethyltransferase T YP_854123.2 3244313 R 405955 CDS YP_854124.1 117625136 4493133 complement(3245855..3247057) 1 NC_008563.1 hypothetical protein 3247057 visC 4493133 visC Escherichia coli APEC O1 hypothetical protein YP_854124.1 3245855 R 405955 CDS YP_854125.1 117625137 4493134 complement(3247080..3248258) 1 NC_008563.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3248258 ubiH 4493134 ubiH Escherichia coli APEC O1 2-octaprenyl-6-methoxyphenyl hydroxylase YP_854125.1 3247080 R 405955 CDS YP_854126.1 117625138 4493135 complement(3248255..3249580) 1 NC_008563.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3249580 pepB 4493135 pepB Escherichia coli APEC O1 proline aminopeptidase P II YP_854126.1 3248255 R 405955 CDS YP_854127.2 229775961 4493136 complement(3249606..3250184) 1 NC_008563.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3250184 ygfB 4493136 ygfB Escherichia coli APEC O1 hypothetical protein YP_854127.2 3249606 R 405955 CDS YP_854128.1 117625140 4493137 3250352..3250681 1 NC_008563.1 Z-ring-associated protein 3250681 4493137 APECO1_3618 Escherichia coli APEC O1 Z-ring-associated protein YP_854128.1 3250352 D 405955 CDS YP_854129.2 229775960 4493138 3250981..3251529 1 NC_008563.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3251529 4493138 APECO1_3617 Escherichia coli APEC O1 ligase YP_854129.2 3250981 D 405955 CDS YP_854130.1 117625142 4493139 complement(3251919..3253151) 1 NC_008563.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3253151 serA 4493139 serA Escherichia coli APEC O1 D-3-phosphoglycerate dehydrogenase YP_854130.1 3251919 R 405955 CDS YP_854131.1 117625143 4493140 complement(3253407..3254102) 1 NC_008563.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3254102 rpiA 4493140 rpiA Escherichia coli APEC O1 ribose-5-phosphate isomerase A YP_854131.1 3253407 R 405955 CDS YP_854132.2 162317571 4493141 3254493..3255386 1 NC_008563.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3255386 iciA 4493141 iciA Escherichia coli APEC O1 chromosome replication initiation inhibitor protein YP_854132.2 3254493 D 405955 CDS YP_854133.1 117625145 4493142 3255589..3256644 1 NC_008563.1 hypothetical protein 3256644 4493142 APECO1_3613 Escherichia coli APEC O1 hypothetical protein YP_854133.1 3255589 D 405955 CDS YP_854134.1 117625146 4493143 complement(3256641..3257537) 1 NC_008563.1 transcriptional regulator YgfI 3257537 ygfI 4493143 ygfI Escherichia coli APEC O1 transcriptional regulator YgfI YP_854134.1 3256641 R 405955 CDS YP_854135.1 117625147 4493144 complement(3257695..3258402) 1 NC_008563.1 hypothetical protein 3258402 yggE 4493144 yggE Escherichia coli APEC O1 hypothetical protein YP_854135.1 3257695 R 405955 CDS YP_854136.1 117625148 4493145 complement(3258528..3259118) 1 NC_008563.1 Involved in the export of arginine; arginine exporter protein 3259118 yggA 4493145 yggA Escherichia coli APEC O1 arginine exporter protein YP_854136.1 3258528 R 405955 CDS YP_854137.1 117625149 4495155 complement(3259299..3260159) 1 NC_008563.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3260159 mscS 4495155 mscS Escherichia coli APEC O1 mechanosensitive channel MscS YP_854137.1 3259299 R 405955 CDS YP_854138.1 117625150 4495156 complement(3260350..3261429) 1 NC_008563.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3261429 fba 4495156 fba Escherichia coli APEC O1 fructose-bisphosphate aldolase YP_854138.1 3260350 R 405955 CDS YP_854139.1 117625151 4495157 complement(3261644..3262807) 1 NC_008563.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3262807 pgk 4495157 pgk Escherichia coli APEC O1 phosphoglycerate kinase YP_854139.1 3261644 R 405955 CDS YP_854140.1 117625152 4495158 complement(3262857..3263876) 1 NC_008563.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3263876 epd 4495158 epd Escherichia coli APEC O1 erythrose 4-phosphate dehydrogenase YP_854140.1 3262857 R 405955 CDS YP_854141.1 117625153 4495159 3264248..3264679 1 NC_008563.1 hypothetical protein 3264679 4495159 APECO1_3605 Escherichia coli APEC O1 hypothetical protein YP_854141.1 3264248 D 405955 CDS YP_854142.1 117625154 4495160 3264702..3265280 1 NC_008563.1 hypothetical protein 3265280 4495160 APECO1_3604 Escherichia coli APEC O1 hypothetical protein YP_854142.1 3264702 D 405955 CDS YP_854143.1 117625155 4495161 3265281..3265988 1 NC_008563.1 permease protein of ABC-type cobalt transporter 3265988 4495161 APECO1_3603 Escherichia coli APEC O1 permease protein of ABC-type cobalt transporter YP_854143.1 3265281 D 405955 CDS YP_854144.1 117625156 4495162 3265976..3266653 1 NC_008563.1 ABC transporter ATP-binding protein 3266653 4495162 APECO1_3602 Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_854144.1 3265976 D 405955 CDS YP_854145.1 117625157 4495163 3266647..3267324 1 NC_008563.1 ABC transporter ATP-binding protein 3267324 4495163 APECO1_3601 Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_854145.1 3266647 D 405955 CDS YP_854146.1 117625158 4495164 complement(3267296..3267919) 1 NC_008563.1 fructose transport system kinase 3267919 frcK 4495164 frcK Escherichia coli APEC O1 fructose transport system kinase YP_854146.1 3267296 R 405955 CDS YP_854147.1 117625159 4495165 complement(3268006..3268515) 1 NC_008563.1 DNA-binding transcriptional regulator 3268515 yggD 4495165 yggD Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_854147.1 3268006 R 405955 CDS YP_854148.1 117625160 4495166 complement(3268849..3270126) 1 NC_008563.1 oxidoreductase 3270126 4495166 APECO1_3598 Escherichia coli APEC O1 oxidoreductase YP_854148.1 3268849 R 405955 CDS YP_854149.1 117625161 4495167 complement(3270141..3271529) 1 NC_008563.1 PTS system, mannitol (cryptic)-specific IIBC component 3271529 cmtA 4495167 cmtA Escherichia coli APEC O1 PTS system, mannitol (cryptic)-specific IIBC component YP_854149.1 3270141 R 405955 CDS YP_854150.1 117625162 4495168 complement(3271557..3272000) 1 NC_008563.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3272000 cmtB 4495168 cmtB Escherichia coli APEC O1 mannitol phosphotransferase subunit EIIA YP_854150.1 3271557 R 405955 CDS YP_854151.1 117625163 4495169 3272377..3273285 1 NC_008563.1 serine protease 3273285 4495169 APECO1_3595 Escherichia coli APEC O1 serine protease YP_854151.1 3272377 D 405955 CDS YP_854152.1 117625164 4495170 complement(3273505..3275496) 1 NC_008563.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3275496 tktA 4495170 tktA Escherichia coli APEC O1 transketolase YP_854152.1 3273505 R 405955 CDS YP_854153.1 117625165 4495171 3275648..3276532 1 NC_008563.1 metalloprotease YggG 3276532 yggG 4495171 yggG Escherichia coli APEC O1 metalloprotease YggG YP_854153.1 3275648 D 405955 CDS YP_854154.1 117625166 4495172 complement(3276736..3277656) 1 NC_008563.1 catalyzes the formation of putrescine from agmatine; agmatinase 3277656 speB 4495172 speB Escherichia coli APEC O1 agmatinase YP_854154.1 3276736 R 405955 CDS YP_854155.1 117625167 4495173 complement(3277792..3278523) 1 NC_008563.1 hypothetical protein 3278523 4495173 APECO1_3591 Escherichia coli APEC O1 hypothetical protein YP_854155.1 3277792 R 405955 CDS YP_854156.1 117625168 4493225 complement(3278669..3280645) 1 NC_008563.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3280645 speA 4493225 speA Escherichia coli APEC O1 arginine decarboxylase YP_854156.1 3278669 R 405955 CDS YP_854157.1 117625169 4493226 3281440..3282594 1 NC_008563.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3282594 metK 4493226 metK Escherichia coli APEC O1 S-adenosylmethionine synthetase YP_854157.1 3281440 D 405955 CDS YP_854158.1 117625170 4493227 3283031..3284425 1 NC_008563.1 D-galactose transporter 3284425 galP 4493227 galP Escherichia coli APEC O1 D-galactose transporter YP_854158.1 3283031 D 405955 CDS YP_854159.1 117625171 4493228 3284502..3284999 1 NC_008563.1 hypothetical protein 3284999 sprT 4493228 sprT Escherichia coli APEC O1 hypothetical protein YP_854159.1 3284502 D 405955 CDS YP_854160.1 117625172 4493229 3285094..3285801 1 NC_008563.1 DNA-specific endonuclease I 3285801 endA 4493229 endA Escherichia coli APEC O1 DNA-specific endonuclease I YP_854160.1 3285094 D 405955 CDS YP_854161.1 117625173 4493230 3285881..3286612 1 NC_008563.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3286612 yggJ 4493230 yggJ Escherichia coli APEC O1 16S ribosomal RNA methyltransferase RsmE YP_854161.1 3285881 D 405955 CDS YP_854162.1 117625174 4493231 3286625..3287575 1 NC_008563.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3287575 gshB 4493231 gshB Escherichia coli APEC O1 glutathione synthetase YP_854162.1 3286625 D 405955 CDS YP_854163.1 117625175 4493232 3287684..3288247 1 NC_008563.1 hypothetical protein 3288247 yqgE 4493232 yqgE Escherichia coli APEC O1 hypothetical protein YP_854163.1 3287684 D 405955 CDS YP_854164.1 117625176 4493233 3288247..3288663 1 NC_008563.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3288663 yqgF 4493233 yqgF Escherichia coli APEC O1 Holliday junction resolvase-like protein YP_854164.1 3288247 D 405955 CDS YP_854165.1 117625177 4493234 complement(3288837..3289817) 1 NC_008563.1 hypothetical protein 3289817 yggR 4493234 yggR Escherichia coli APEC O1 hypothetical protein YP_854165.1 3288837 R 405955 CDS YP_854166.1 117625178 4493235 3289835..3290539 1 NC_008563.1 hypothetical protein 3290539 yggS 4493235 yggS Escherichia coli APEC O1 hypothetical protein YP_854166.1 3289835 D 405955 CDS YP_854167.1 117625179 4493236 3290557..3291123 1 NC_008563.1 hypothetical protein 3291123 yggT 4493236 yggT Escherichia coli APEC O1 hypothetical protein YP_854167.1 3290557 D 405955 CDS YP_854168.1 117625180 4493237 3291120..3291410 1 NC_008563.1 hypothetical protein 3291410 yggU 4493237 yggU Escherichia coli APEC O1 hypothetical protein YP_854168.1 3291120 D 405955 CDS YP_854169.1 117625181 4493238 3291418..3292011 1 NC_008563.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3292011 yggV 4493238 yggV Escherichia coli APEC O1 deoxyribonucleotide triphosphate pyrophosphatase YP_854169.1 3291418 D 405955 CDS YP_854170.1 117625182 4493239 3292004..3293140 1 NC_008563.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3293140 yggW 4493239 yggW Escherichia coli APEC O1 coproporphyrinogen III oxidase YP_854170.1 3292004 D 405955 CDS YP_854171.1 117625183 4493240 complement(3293209..3294180) 1 NC_008563.1 hypothetical protein 3294180 yggM 4493240 yggM Escherichia coli APEC O1 hypothetical protein YP_854171.1 3293209 R 405955 CDS YP_854172.1 117625184 4493241 complement(3294333..3295379) 1 NC_008563.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3295379 ansB 4493241 ansB Escherichia coli APEC O1 L-asparaginase II YP_854172.1 3294333 R 405955 CDS YP_854173.1 117625185 4493242 complement(3295555..3296274) 1 NC_008563.1 hypothetical protein 3296274 yggN 4493242 yggN Escherichia coli APEC O1 hypothetical protein YP_854173.1 3295555 R 405955 CDS YP_854174.1 117625186 4493243 complement(3296458..3296784) 1 NC_008563.1 hypothetical protein 3296784 yggL 4493243 yggL Escherichia coli APEC O1 hypothetical protein YP_854174.1 3296458 R 405955 CDS YP_854175.1 117625187 4493244 complement(3296784..3297503) 1 NC_008563.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3297503 trmB 4493244 trmB Escherichia coli APEC O1 tRNA (guanine-N(7)-)-methyltransferase YP_854175.1 3296784 R 405955 CDS YP_854176.1 117625188 4493812 3297664..3298716 1 NC_008563.1 adenine DNA glycosylase 3298716 mutY 4493812 mutY Escherichia coli APEC O1 adenine DNA glycosylase YP_854176.1 3297664 D 405955 CDS YP_854177.1 117625189 4493813 3298744..3299019 1 NC_008563.1 hypothetical protein 3299019 yggX 4493813 yggX Escherichia coli APEC O1 hypothetical protein YP_854177.1 3298744 D 405955 CDS YP_854206.1 117625190 4493814 3299081..3300163 1 NC_008563.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3300163 mltC 4493814 mltC Escherichia coli APEC O1 murein transglycosylase C YP_854206.1 3299081 D 405955 CDS YP_854208.1 117625191 4493815 3300317..3301621 1 NC_008563.1 transport of nucleosides, permease protein 3301621 nupG 4493815 nupG Escherichia coli APEC O1 transport of nucleosides, permease protein YP_854208.1 3300317 D 405955 CDS YP_854211.1 117625192 4493816 complement(3301670..3303805) 1 NC_008563.1 ornithine decarboxylase 3303805 speC 4493816 speC Escherichia coli APEC O1 ornithine decarboxylase YP_854211.1 3301670 R 405955 CDS YP_854213.1 117625193 4493817 3304303..3304911 1 NC_008563.1 hypothetical protein 3304911 yqgA 4493817 yqgA Escherichia coli APEC O1 hypothetical protein YP_854213.1 3304303 D 405955 CDS YP_854214.1 117625194 4493818 3305290..3306552 1 NC_008563.1 integrase core domain; P4-like integrase 3306552 4493818 APECO1_3534 Escherichia coli APEC O1 P4-like integrase YP_854214.1 3305290 D 405955 CDS YP_854225.1 117625195 4493819 complement(3306652..3306915) 1 NC_008563.1 hypothetical protein 3306915 4493819 APECO1_3533 Escherichia coli APEC O1 hypothetical protein YP_854225.1 3306652 R 405955 CDS YP_854230.1 117625196 4493820 3306992..3310519 1 NC_008563.1 superfamily I DNA helicase 3310519 4493820 APECO1_3532 Escherichia coli APEC O1 superfamily I DNA helicase YP_854230.1 3306992 D 405955 CDS YP_854244.1 117625197 4493821 complement(3310628..3312127) 1 NC_008563.1 hypothetical protein 3312127 4493821 APECO1_3531 Escherichia coli APEC O1 hypothetical protein YP_854244.1 3310628 R 405955 CDS YP_854245.1 117625198 4493822 complement(3312302..3313057) 1 NC_008563.1 tia invasion determinant 3313057 tia 4493822 tia Escherichia coli APEC O1 tia invasion determinant YP_854245.1 3312302 R 405955 CDS YP_854246.1 117625199 4493823 complement(3313158..3313907) 1 NC_008563.1 ISEc12 ATP-binding protein 3313907 4493823 APECO1_3529 Escherichia coli APEC O1 ISEc12 ATP-binding protein YP_854246.1 3313158 R 405955 CDS YP_854247.1 117625200 4493824 complement(3313919..3315460) 1 NC_008563.1 transposase for ISEc12 3315460 4493824 APECO1_3528 Escherichia coli APEC O1 transposase for ISEc12 YP_854247.1 3313919 R 405955 CDS YP_854248.1 117625201 4493827 complement(3315994..3317004) 1 NC_008563.1 allele II; protein PapG 3317004 papG 4493827 papG Escherichia coli APEC O1 protein PapG YP_854248.1 3315994 R 405955 CDS YP_854249.1 117625202 4493828 complement(3317048..3317578) 1 NC_008563.1 P pilus minor tip component PapF 3317578 papF 4493828 papF Escherichia coli APEC O1 P pilus minor tip component PapF YP_854249.1 3317048 R 405955 CDS YP_854250.1 117625203 4493829 complement(3317623..3318144) 1 NC_008563.1 PapE protein 3318144 papE 4493829 papE Escherichia coli APEC O1 PapE protein YP_854250.1 3317623 R 405955 CDS YP_854251.1 117625204 4493830 complement(3318171..3318707) 1 NC_008563.1 pilus assembly protein PapK 3318707 papK 4493830 papK Escherichia coli APEC O1 pilus assembly protein PapK YP_854251.1 3318171 R 405955 CDS YP_854252.1 117625205 4493547 complement(3318717..3319298) 1 NC_008563.1 PapJ protein 3319298 papJ 4493547 papJ Escherichia coli APEC O1 PapJ protein YP_854252.1 3318717 R 405955 CDS YP_854253.1 117625206 4493548 complement(3319335..3320069) 1 NC_008563.1 pilus assembly protein chaperone PapD 3320069 papD 4493548 papD Escherichia coli APEC O1 pilus assembly protein chaperone PapD YP_854253.1 3319335 R 405955 CDS YP_854254.1 117625207 4493549 complement(3320140..3322659) 1 NC_008563.1 outer membrane usher protein PapC 3322659 papC 4493549 papC Escherichia coli APEC O1 outer membrane usher protein PapC YP_854254.1 3320140 R 405955 CDS YP_854255.1 117625208 4493550 complement(3322709..3323296) 1 NC_008563.1 minor pilin subunit PapH 3323296 papH 4493550 papH Escherichia coli APEC O1 minor pilin subunit PapH YP_854255.1 3322709 R 405955 CDS YP_854256.1 117625209 4493551 complement(3323359..3323928) 1 NC_008563.1 major fibrial protein 3323928 papA 4493551 papA Escherichia coli APEC O1 major fibrial protein YP_854256.1 3323359 R 405955 CDS YP_854257.1 117625210 4493552 complement(3324114..3324428) 1 NC_008563.1 fimbrial regulatory protein; PapB-like protein 3324428 4493552 APECO1_3518 Escherichia coli APEC O1 PapB-like protein YP_854257.1 3324114 R 405955 CDS YP_854258.1 117625211 4493553 complement(3324732..3325037) 1 NC_008563.1 fimbrial regulatory protein 3325037 papI 4493553 papI Escherichia coli APEC O1 fimbrial regulatory protein YP_854258.1 3324732 R 405955 CDS YP_854259.1 117625212 4493554 3325337..3325663 1 NC_008563.1 hypothetical protein 3325663 4493554 APECO1_3516 Escherichia coli APEC O1 hypothetical protein YP_854259.1 3325337 D 405955 CDS YP_854260.1 117625213 4493555 complement(3325741..3326316) 1 NC_008563.1 hypothetical protein 3326316 4493555 APECO1_3515 Escherichia coli APEC O1 hypothetical protein YP_854260.1 3325741 R 405955 CDS YP_854261.1 117625214 4493556 complement(3326574..3327140) 1 NC_008563.1 hypothetical protein 3327140 4493556 APECO1_3514 Escherichia coli APEC O1 hypothetical protein YP_854261.1 3326574 R 405955 CDS YP_854262.1 117625215 4493557 3327566..3327856 1 NC_008563.1 IS2 transposase 3327856 insC 4493557 insC Escherichia coli APEC O1 IS2 transposase YP_854262.1 3327566 D 405955 CDS YP_854263.1 117625216 4493558 3327814..3328527 1 NC_008563.1 IS2 transposase 3328527 insD 4493558 insD Escherichia coli APEC O1 IS2 transposase YP_854263.1 3327814 D 405955 CDS YP_854264.1 117625217 4493559 complement(3328729..3329094) 1 NC_008563.1 hypothetical protein 3329094 4493559 APECO1_3511 Escherichia coli APEC O1 hypothetical protein YP_854264.1 3328729 R 405955 CDS YP_854265.1 117625218 4493560 complement(3329137..3330501) 1 NC_008563.1 phosphoglycerate transporter protein PgtP 3330501 pgtP 4493560 pgtP Escherichia coli APEC O1 phosphoglycerate transporter protein PgtP YP_854265.1 3329137 R 405955 CDS YP_854266.1 117625219 4493561 3330846..3332117 1 NC_008563.1 phosphoglycerate transport regulatory protein 3332117 pgtC 4493561 pgtC Escherichia coli APEC O1 phosphoglycerate transport regulatory protein YP_854266.1 3330846 D 405955 CDS YP_854267.1 117625220 4493562 3332114..3334123 1 NC_008563.1 regulatory protein 3334123 pgtB 4493562 pgtB Escherichia coli APEC O1 regulatory protein YP_854267.1 3332114 D 405955 CDS YP_854268.1 117625221 4493563 3334104..3335360 1 NC_008563.1 phosphoglycerate activator protein 3335360 pgtA 4493563 pgtA Escherichia coli APEC O1 phosphoglycerate activator protein YP_854268.1 3334104 D 405955 CDS YP_854270.1 117625222 4493564 complement(3335953..3336258) 1 NC_008563.1 hypothetical protein 3336258 4493564 APECO1_3506 Escherichia coli APEC O1 hypothetical protein YP_854270.1 3335953 R 405955 CDS YP_854272.1 117625223 4493565 complement(3336341..3336985) 1 NC_008563.1 hypothetical protein 3336985 4493565 APECO1_3505 Escherichia coli APEC O1 hypothetical protein YP_854272.1 3336341 R 405955 CDS YP_854275.1 117625224 4493566 complement(3337006..3337275) 1 NC_008563.1 similar to transcriptional regulator; hypothetical protein 3337275 4493566 APECO1_3504 Escherichia coli APEC O1 hypothetical protein YP_854275.1 3337006 R 405955 CDS YP_854305.1 117625225 4491363 complement(3337436..3337999) 1 NC_008563.1 hypothetical protein 3337999 4491363 APECO1_3503 Escherichia coli APEC O1 hypothetical protein YP_854305.1 3337436 R 405955 CDS YP_854308.1 117625226 4491364 complement(3337984..3339216) 1 NC_008563.1 hypothetical protein 3339216 4491364 APECO1_3502 Escherichia coli APEC O1 hypothetical protein YP_854308.1 3337984 R 405955 CDS YP_854310.1 117625227 4491365 complement(3339352..3339996) 1 NC_008563.1 hypothetical protein 3339996 4491365 APECO1_3501 Escherichia coli APEC O1 hypothetical protein YP_854310.1 3339352 R 405955 CDS YP_854311.1 117625228 4491366 complement(3340190..3341638) 1 NC_008563.1 hypothetical protein 3341638 4491366 APECO1_3500 Escherichia coli APEC O1 hypothetical protein YP_854311.1 3340190 R 405955 CDS YP_854312.1 117625229 4491367 complement(3341809..3342696) 1 NC_008563.1 transposase for IS629 3342696 4491367 APECO1_3499 Escherichia coli APEC O1 transposase for IS629 YP_854312.1 3341809 R 405955 CDS YP_854313.1 117625230 4491368 complement(3342696..3343022) 1 NC_008563.1 transposase; OrfA protein of insertion sequence IS629 3343022 4491368 APECO1_3498 Escherichia coli APEC O1 transposase; OrfA protein of insertion sequence IS629 YP_854313.1 3342696 R 405955 CDS YP_854314.1 117625231 4491369 complement(3344416..3346464) 1 NC_008563.1 iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein; iron-regulated outer membrane virulence protein 3346464 ireA 4491369 ireA Escherichia coli APEC O1 iron-regulated outer membrane virulence protein YP_854314.1 3344416 R 405955 CDS YP_854315.1 117625232 4491370 complement(3347238..3347978) 1 NC_008563.1 hypothetical protein 3347978 4491370 APECO1_3496 Escherichia coli APEC O1 hypothetical protein YP_854315.1 3347238 R 405955 CDS YP_854316.1 117625233 4491371 3349670..3350458 1 NC_008563.1 hypothetical protein 3350458 4491371 APECO1_3495 Escherichia coli APEC O1 hypothetical protein YP_854316.1 3349670 D 405955 CDS YP_854317.1 117625234 4491372 complement(3350455..3351405) 1 NC_008563.1 hypothetical protein 3351405 4491372 APECO1_3494 Escherichia coli APEC O1 hypothetical protein YP_854317.1 3350455 R 405955 CDS YP_854318.1 117625235 4491373 3351511..3352395 1 NC_008563.1 hypothetical protein 3352395 4491373 APECO1_3493 Escherichia coli APEC O1 hypothetical protein YP_854318.1 3351511 D 405955 CDS YP_854319.1 117625236 4491374 3352598..3353278 1 NC_008563.1 transcriptional regulator 3353278 4491374 APECO1_3492 Escherichia coli APEC O1 transcriptional regulator YP_854319.1 3352598 D 405955 CDS YP_854320.1 117625237 4491375 3353321..3354103 1 NC_008563.1 hypothetical protein 3354103 4491375 APECO1_3491 Escherichia coli APEC O1 hypothetical protein YP_854320.1 3353321 D 405955 CDS YP_854321.1 117625238 4491376 3354432..3355250 1 NC_008563.1 hypothetical protein 3355250 yafZ 4491376 yafZ Escherichia coli APEC O1 hypothetical protein YP_854321.1 3354432 D 405955 CDS YP_854322.1 117625239 4491377 3355341..3355826 1 NC_008563.1 hypothetical protein 3355826 yfjX 4491377 yfjX Escherichia coli APEC O1 hypothetical protein YP_854322.1 3355341 D 405955 CDS YP_854323.1 117625240 4491378 3355841..3356317 1 NC_008563.1 radC-like protein YeeS 3356317 yeeS 4491378 yeeS Escherichia coli APEC O1 radC-like protein YeeS YP_854323.1 3355841 D 405955 CDS YP_854324.1 117625241 4491379 3356626..3357063 1 NC_008563.1 hypothetical protein 3357063 yeeU 4491379 yeeU Escherichia coli APEC O1 hypothetical protein YP_854324.1 3356626 D 405955 CDS YP_854325.1 117625242 4491380 3357110..3357487 1 NC_008563.1 hypothetical protein 3357487 yeeV 4491380 yeeV Escherichia coli APEC O1 hypothetical protein YP_854325.1 3357110 D 405955 CDS YP_854326.1 117625243 4491381 3357484..3357972 1 NC_008563.1 hypothetical protein 3357972 4491381 APECO1_3485 Escherichia coli APEC O1 hypothetical protein YP_854326.1 3357484 D 405955 CDS YP_854327.1 117625244 4494199 3358266..3359111 1 NC_008563.1 hypothetical protein 3359111 4494199 APECO1_3484 Escherichia coli APEC O1 hypothetical protein YP_854327.1 3358266 D 405955 CDS YP_854328.1 117625245 4494200 3359182..3360717 1 NC_008563.1 hypothetical protein 3360717 4494200 APECO1_3483 Escherichia coli APEC O1 hypothetical protein YP_854328.1 3359182 D 405955 CDS YP_854329.1 117625246 4494201 3362058..3363077 1 NC_008563.1 polysialic acid capsule synthesis protein KpsF 3363077 kpsF 4494201 kpsF Escherichia coli APEC O1 polysialic acid capsule synthesis protein KpsF YP_854329.1 3362058 D 405955 CDS YP_854330.1 117625247 4494202 3363149..3364297 1 NC_008563.1 polysialic acid transport protein KpsE 3364297 kpsE 4494202 kpsE Escherichia coli APEC O1 polysialic acid transport protein KpsE YP_854330.1 3363149 D 405955 CDS YP_854331.1 117625248 4494203 3364321..3365997 1 NC_008563.1 polysialic acid transport protein KpsD precursor 3365997 kpsD 4494203 kpsD Escherichia coli APEC O1 polysialic acid transport protein KpsD precursor YP_854331.1 3364321 D 405955 CDS YP_854332.1 117625249 4494204 3366007..3366747 1 NC_008563.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3366747 kpsU 4494204 kpsU Escherichia coli APEC O1 3-deoxy-manno-octulosonate cytidylyltransferase YP_854332.1 3366007 D 405955 CDS YP_854335.1 117625250 4494205 3366744..3368771 1 NC_008563.1 capsule polysaccharide export protein KpsC 3368771 kpsC 4494205 kpsC Escherichia coli APEC O1 capsule polysaccharide export protein KpsC YP_854335.1 3366744 D 405955 CDS YP_854344.1 117625251 4494206 3368806..3370011 1 NC_008563.1 polysialic acid capsule synthesis protein KpsS 3370011 kpsS 4494206 kpsS Escherichia coli APEC O1 polysialic acid capsule synthesis protein KpsS YP_854344.1 3368806 D 405955 CDS YP_854390.1 117625252 4494207 complement(3370161..3371390) 1 NC_008563.1 poly-alpha-2,8 sialosyl sialyltransferase NeuS 3371390 neuS 4494207 neuS Escherichia coli APEC O1 poly-alpha-2,8 sialosyl sialyltransferase NeuS YP_854390.1 3370161 R 405955 CDS YP_854391.1 117625253 4494208 complement(3371380..3372555) 1 NC_008563.1 polysialic acid biosynthesis protein NeuE 3372555 neuE 4494208 neuE Escherichia coli APEC O1 polysialic acid biosynthesis protein NeuE YP_854391.1 3371380 R 405955 CDS YP_854392.1 117625254 4494209 complement(3372521..3373696) 1 NC_008563.1 polysialic acid biosynthesis protein 3373696 neuC 4494209 neuC Escherichia coli APEC O1 polysialic acid biosynthesis protein YP_854392.1 3372521 R 405955 CDS YP_854393.1 117625255 4494210 complement(3373693..3374949) 1 NC_008563.1 acylneuraminate cytidylyltransferase 3374949 neuA 4494210 neuA Escherichia coli APEC O1 acylneuraminate cytidylyltransferase YP_854393.1 3373693 R 405955 CDS YP_854394.1 117625256 4494211 complement(3374949..3375989) 1 NC_008563.1 sialic acid synthase 3375989 neuB 4494211 neuB Escherichia coli APEC O1 sialic acid synthase YP_854394.1 3374949 R 405955 CDS YP_854395.1 117625257 4494212 complement(3375986..3376609) 1 NC_008563.1 sialic acid synthase 3376609 neuD 4494212 neuD Escherichia coli APEC O1 sialic acid synthase YP_854395.1 3375986 R 405955 CDS YP_854396.1 117625258 4494213 complement(3376659..3377318) 1 NC_008563.1 polysialic acid transport ATP-binding protein KpsT 3377318 kpsT 4494213 kpsT Escherichia coli APEC O1 polysialic acid transport ATP-binding protein KpsT YP_854396.1 3376659 R 405955 CDS YP_854397.1 117625259 4494214 complement(3377315..3378091) 1 NC_008563.1 polysialic acid transport protein KpsM 3378091 kpsM 4494214 kpsM Escherichia coli APEC O1 polysialic acid transport protein KpsM YP_854397.1 3377315 R 405955 CDS YP_854398.1 117625260 4494215 complement(3379149..3379685) 1 NC_008563.1 general secretion pathway protein YghD 3379685 gspM 4494215 gspM Escherichia coli APEC O1 general secretion pathway protein YghD YP_854398.1 3379149 R 405955 CDS YP_854399.2 162317570 4494216 complement(3379687..3380547) 1 NC_008563.1 similar to general secretory pathway protein L; GspL-like protein 3380547 gspL 4494216 gspL Escherichia coli APEC O1 GspL-like protein YP_854399.2 3379687 R 405955 CDS YP_854400.1 117625262 4494217 complement(3380862..3381839) 1 NC_008563.1 type II secretion protein GspK 3381839 gspK 4494217 gspK Escherichia coli APEC O1 type II secretion protein GspK YP_854400.1 3380862 R 405955 CDS YP_854401.1 117625263 4494218 complement(3381836..3382441) 1 NC_008563.1 type II secretion protein GspJ 3382441 gspJ 4494218 gspJ Escherichia coli APEC O1 type II secretion protein GspJ YP_854401.1 3381836 R 405955 CDS YP_854402.1 117625264 4491811 complement(3382438..3382809) 1 NC_008563.1 type II secretion protein GspI 3382809 gspI 4491811 gspI Escherichia coli APEC O1 type II secretion protein GspI YP_854402.1 3382438 R 405955 CDS YP_854403.1 117625265 4491812 complement(3382806..3383369) 1 NC_008563.1 type II secretion protein GspH 3383369 gspH 4491812 gspH Escherichia coli APEC O1 type II secretion protein GspH YP_854403.1 3382806 R 405955 CDS YP_854404.1 117625266 4491813 complement(3383373..3383828) 1 NC_008563.1 type II secretion protein GspG 3383828 gspG 4491813 gspG Escherichia coli APEC O1 type II secretion protein GspG YP_854404.1 3383373 R 405955 CDS YP_854405.1 117625267 4491814 complement(3383845..3385068) 1 NC_008563.1 type II secretion protein GspF 3385068 gspF 4491814 gspF Escherichia coli APEC O1 type II secretion protein GspF YP_854405.1 3383845 R 405955 CDS YP_854406.1 117625268 4491815 complement(3385068..3386561) 1 NC_008563.1 type II secretion protein GspE 3386561 gspE 4491815 gspE Escherichia coli APEC O1 type II secretion protein GspE YP_854406.1 3385068 R 405955 CDS YP_854407.1 117625269 4491816 complement(3386561..3388621) 1 NC_008563.1 type II secretion protein GspD 3388621 gspD 4491816 gspD Escherichia coli APEC O1 type II secretion protein GspD YP_854407.1 3386561 R 405955 CDS YP_854408.1 117625270 4491817 complement(3388651..3389493) 1 NC_008563.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC 3389493 gspC 4491817 gspC Escherichia coli APEC O1 type II secretion protein GspC YP_854408.1 3388651 R 405955 CDS YP_854410.1 117625271 4491818 complement(3389628..3390038) 1 NC_008563.1 hypothetical protein 3390038 4491818 APECO1_3456 Escherichia coli APEC O1 hypothetical protein YP_854410.1 3389628 R 405955 CDS YP_854416.1 117625272 4491819 complement(3390104..3391009) 1 NC_008563.1 prepilin peptidase A 3391009 pppA 4491819 pppA Escherichia coli APEC O1 prepilin peptidase A YP_854416.1 3390104 R 405955 CDS YP_854419.1 117625273 4491820 complement(3391077..3395639) 1 NC_008563.1 lipoprotein AcfD-like 3395639 yghJ 4491820 yghJ Escherichia coli APEC O1 lipoprotein AcfD-like YP_854419.1 3391077 R 405955 CDS YP_854446.1 117625274 4491821 3395790..3396095 1 NC_008563.1 hypothetical protein 3396095 4491821 APECO1_3453 Escherichia coli APEC O1 hypothetical protein YP_854446.1 3395790 D 405955 CDS YP_854447.1 117625275 4491822 complement(3396123..3397805) 1 NC_008563.1 glycolate transporter 3397805 yghK 4491822 yghK Escherichia coli APEC O1 glycolate transporter YP_854447.1 3396123 R 405955 CDS YP_854448.1 117625276 4491823 complement(3398161..3400332) 1 NC_008563.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3400332 glcB 4491823 glcB Escherichia coli APEC O1 malate synthase G YP_854448.1 3398161 R 405955 CDS YP_854449.1 117625277 4491824 complement(3400354..3400758) 1 NC_008563.1 hypothetical protein 3400758 glcC 4491824 glcC Escherichia coli APEC O1 hypothetical protein YP_854449.1 3400354 R 405955 CDS YP_854450.1 117625278 4491825 complement(3401997..3403049) 1 NC_008563.1 glycolate oxidase FAD binding subunit 3403049 glcE 4491825 glcE Escherichia coli APEC O1 glycolate oxidase FAD binding subunit YP_854450.1 3401997 R 405955 CDS YP_854451.1 117625279 4491826 complement(3403049..3404548) 1 NC_008563.1 glycolate oxidase subunit GlcD 3404548 glcD 4491826 glcD Escherichia coli APEC O1 glycolate oxidase subunit GlcD YP_854451.1 3403049 R 405955 CDS YP_854452.1 117625280 4491827 3404739..3405563 1 NC_008563.1 DNA-binding transcriptional regulator GlcC 3405563 glcC 4491827 glcC Escherichia coli APEC O1 DNA-binding transcriptional regulator GlcC YP_854452.1 3404739 D 405955 CDS YP_854453.1 117625281 4491828 complement(3405570..3406712) 1 NC_008563.1 hypothetical protein 3406712 4491828 APECO1_3446 Escherichia coli APEC O1 hypothetical protein YP_854453.1 3405570 R 405955 CDS YP_854454.1 117625282 4491829 3407083..3408807 1 NC_008563.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3408807 4491829 APECO1_3445 Escherichia coli APEC O1 acyl-CoA synthetase YP_854454.1 3407083 D 405955 CDS YP_854455.1 117625283 4494238 3408594..3409718 1 NC_008563.1 hypothetical protein 3409718 4494238 APECO1_3444 Escherichia coli APEC O1 hypothetical protein YP_854455.1 3408594 D 405955 CDS YP_854456.1 117625284 4494239 3409998..3411170 1 NC_008563.1 7-keto-8-aminopelargonate synthetase and related enzymes family; hypothetical protein 3411170 4494239 APECO1_3443 Escherichia coli APEC O1 hypothetical protein YP_854456.1 3409998 D 405955 CDS YP_854457.1 117625285 4494240 complement(3411205..3412284) 1 NC_008563.1 permease 3412284 4494240 APECO1_3442 Escherichia coli APEC O1 permease YP_854457.1 3411205 R 405955 CDS YP_854458.1 117625286 4494241 complement(3412281..3413351) 1 NC_008563.1 permease 3413351 4494241 APECO1_3441 Escherichia coli APEC O1 permease YP_854458.1 3412281 R 405955 CDS YP_854459.1 117625287 4494242 complement(3413382..3413942) 1 NC_008563.1 transcriptional regulator 3413942 ytfJ 4494242 ytfJ Escherichia coli APEC O1 transcriptional regulator YP_854459.1 3413382 R 405955 CDS YP_854460.1 117625288 4494243 complement(3413942..3414778) 1 NC_008563.1 hypothetical protein 3414778 4494243 APECO1_3439 Escherichia coli APEC O1 hypothetical protein YP_854460.1 3413942 R 405955 CDS YP_854461.1 117625289 4494244 complement(3414778..3415989) 1 NC_008563.1 hypothetical protein 3415989 yghQ 4494244 yghQ Escherichia coli APEC O1 hypothetical protein YP_854461.1 3414778 R 405955 CDS YP_854462.1 117625290 4494245 complement(3416173..3416943) 1 NC_008563.1 hypothetical protein 3416943 4494245 APECO1_3437 Escherichia coli APEC O1 hypothetical protein YP_854462.1 3416173 R 405955 CDS YP_854463.1 117625291 4494246 complement(3416963..3417676) 1 NC_008563.1 ATP-binding protein YghS 3417676 yghS 4494246 yghS Escherichia coli APEC O1 ATP-binding protein YghS YP_854463.1 3416963 R 405955 CDS YP_854464.1 117625292 4494247 3417851..3418543 1 NC_008563.1 nucleoside triphosphate hydrolase domain-containing protein 3418543 yghT 4494247 yghT Escherichia coli APEC O1 nucleoside triphosphate hydrolase domain-containing protein YP_854464.1 3417851 D 405955 CDS YP_854465.1 117625293 4494248 complement(3418592..3420091) 1 NC_008563.1 low-affinity inorganic phosphate transporter 2 3420091 pitB 4494248 pitB Escherichia coli APEC O1 low-affinity inorganic phosphate transporter 2 YP_854465.1 3418592 R 405955 CDS YP_854466.1 117625294 4494249 complement(3420383..3422245) 1 NC_008563.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3422245 gsp 4494249 gsp Escherichia coli APEC O1 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_854466.1 3420383 R 405955 CDS YP_854467.1 117625295 4494250 3422399..3423313 1 NC_008563.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 3423313 yghU 4494250 yghU Escherichia coli APEC O1 glutathione S-transferase YP_854467.1 3422399 D 405955 CDS YP_854468.1 117625296 4493010 complement(3423707..3424102) 1 NC_008563.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3424102 hybF 4493010 hybF Escherichia coli APEC O1 hydrogenase nickel incorporation protein HybF YP_854468.1 3423707 R 405955 CDS YP_854469.1 117625297 4493011 complement(3424041..3424529) 1 NC_008563.1 hydrogenase 2-specific chaperone 3424529 hybE 4493011 hybE Escherichia coli APEC O1 hydrogenase 2-specific chaperone YP_854469.1 3424041 R 405955 CDS YP_854481.1 117625298 4493012 complement(3424522..3425016) 1 NC_008563.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3425016 hybD 4493012 hybD Escherichia coli APEC O1 hydrogenase 2 maturation endopeptidase YP_854481.1 3424522 R 405955 CDS YP_854500.1 117625299 4493013 complement(3425016..3426719) 1 NC_008563.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3426719 hybC 4493013 hybC Escherichia coli APEC O1 hydrogenase 2 large subunit YP_854500.1 3425016 R 405955 CDS YP_854501.1 117625300 4493014 complement(3426716..3427894) 1 NC_008563.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3427894 hybB 4493014 hybB Escherichia coli APEC O1 hydrogenase 2 b cytochrome subunit YP_854501.1 3426716 R 405955 CDS YP_854502.1 117625301 4493015 complement(3427884..3428870) 1 NC_008563.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3428870 hybA 4493015 hybA Escherichia coli APEC O1 hydrogenase 2 protein HybA YP_854502.1 3427884 R 405955 CDS YP_854503.1 117625302 4493016 complement(3428873..3429991) 1 NC_008563.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3429991 hybO 4493016 hybO Escherichia coli APEC O1 hydrogenase 2 small subunit YP_854503.1 3428873 R 405955 CDS YP_854504.1 117625303 4493017 complement(3430180..3430467) 1 NC_008563.1 hypothetical protein 3430467 yghW 4493017 yghW Escherichia coli APEC O1 hypothetical protein YP_854504.1 3430180 R 405955 CDS YP_854505.1 117625304 4493018 complement(3430586..3431512) 1 NC_008563.1 hydrolase 3431512 4493018 APECO1_3423 Escherichia coli APEC O1 hydrolase YP_854505.1 3430586 R 405955 CDS YP_854506.1 117625305 4493019 3431630..3432670 1 NC_008563.1 aldo-keto reductase 3432670 yghZ 4493019 yghZ Escherichia coli APEC O1 aldo-keto reductase YP_854506.1 3431630 D 405955 CDS YP_854507.1 117625306 4493020 complement(3432710..3433204) 1 NC_008563.1 hypothetical protein 3433204 yqhA 4493020 yqhA Escherichia coli APEC O1 hypothetical protein YP_854507.1 3432710 R 405955 CDS YP_854508.1 117625307 4493021 3433392..3434279 1 NC_008563.1 oxidoreductase 3434279 yghA 4493021 yghA Escherichia coli APEC O1 oxidoreductase YP_854508.1 3433392 D 405955 CDS YP_854509.1 117625308 4493022 complement(3434318..3434743) 1 NC_008563.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3434743 exbD 4493022 exbD Escherichia coli APEC O1 biopolymer transport protein ExbD YP_854509.1 3434318 R 405955 CDS YP_854510.1 117625309 4493023 complement(3434750..3435484) 1 NC_008563.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3435484 exbB 4493023 exbB Escherichia coli APEC O1 biopolymer transport protein ExbB YP_854510.1 3434750 R 405955 CDS YP_854511.1 117625310 4493024 3435658..3436923 1 NC_008563.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3436923 metC 4493024 metC Escherichia coli APEC O1 cystathionine beta-lyase YP_854511.1 3435658 D 405955 CDS YP_854512.1 117625311 4493025 3437063..3437722 1 NC_008563.1 hypothetical protein 3437722 yghB 4493025 yghB Escherichia coli APEC O1 hypothetical protein YP_854512.1 3437063 D 405955 CDS YP_854513.1 117625312 4493026 complement(3437762..3438829) 1 NC_008563.1 DNA-binding transcriptional regulator 3438829 yqhC 4493026 yqhC Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_854513.1 3437762 R 405955 CDS YP_854514.1 117625313 4493027 3438855..3440018 1 NC_008563.1 alcohol dehydrogenase 3440018 yqhD 4493027 yqhD Escherichia coli APEC O1 alcohol dehydrogenase YP_854514.1 3438855 D 405955 CDS YP_854515.1 117625314 4493028 3440123..3440950 1 NC_008563.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3440950 dkgA 4493028 dkgA Escherichia coli APEC O1 2,5-diketo-D-gluconate reductase A YP_854515.1 3440123 D 405955 CDS YP_854516.1 117625315 4491577 3441150..3442076 1 NC_008563.1 hypothetical protein 3442076 yqhG 4491577 yqhG Escherichia coli APEC O1 hypothetical protein YP_854516.1 3441150 D 405955 CDS YP_854517.1 117625316 4491578 3442127..3442384 1 NC_008563.1 outer membrane lipoprotein 3442384 yqhH 4491578 yqhH Escherichia coli APEC O1 outer membrane lipoprotein YP_854517.1 3442127 D 405955 CDS YP_854518.1 117625317 4491579 complement(3442426..3444645) 1 NC_008563.1 hypothetical protein 3444645 ygiRQ 4491579 ygiRQ Escherichia coli APEC O1 hypothetical protein YP_854518.1 3442426 R 405955 CDS YP_854519.1 117625318 4491580 3444897..3445646 1 NC_008563.1 regulator 3445646 4491580 APECO1_3409 Escherichia coli APEC O1 regulator YP_854519.1 3444897 D 405955 CDS YP_854520.1 117625319 4491581 3445969..3447441 1 NC_008563.1 oxidoreductase YdfI 3447441 4491581 APECO1_3408 Escherichia coli APEC O1 oxidoreductase YdfI YP_854520.1 3445969 D 405955 CDS YP_854521.1 117625320 4491582 3447438..3448454 1 NC_008563.1 zinc-type alcohol dehydrogenase-like protein YjjN 3448454 4491582 APECO1_3407 Escherichia coli APEC O1 zinc-type alcohol dehydrogenase-like protein YjjN YP_854521.1 3447438 D 405955 CDS YP_854522.1 117625321 4491583 3448465..3449475 1 NC_008563.1 ureidoglycolate dehydrogenase 3449475 4491583 APECO1_3406 Escherichia coli APEC O1 ureidoglycolate dehydrogenase YP_854522.1 3448465 D 405955 CDS YP_854523.1 117625322 4491584 3449548..3450531 1 NC_008563.1 c4-dicarboxylate transport system binding protein 3450531 4491584 APECO1_3405 Escherichia coli APEC O1 c4-dicarboxylate transport system binding protein YP_854523.1 3449548 D 405955 CDS YP_854524.1 117625323 4491585 3450573..3451055 1 NC_008563.1 hypothetical protein 3451055 4491585 APECO1_3404 Escherichia coli APEC O1 hypothetical protein YP_854524.1 3450573 D 405955 CDS YP_854525.1 117625324 4491586 3451066..3452370 1 NC_008563.1 c4-dicarboxylate permease 3452370 ygiK 4491586 ygiK Escherichia coli APEC O1 c4-dicarboxylate permease YP_854525.1 3451066 D 405955 CDS YP_854526.1 117625325 4491587 complement(3452441..3453853) 1 NC_008563.1 repressor protein for FtsI 3453853 sufI 4491587 sufI Escherichia coli APEC O1 repressor protein for FtsI YP_854526.1 3452441 R 405955 CDS YP_854528.1 117625326 4491588 complement(3453928..3454665) 1 NC_008563.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 3454665 plsC 4491588 plsC Escherichia coli APEC O1 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_854528.1 3453928 R 405955 CDS YP_854531.1 117625327 4491589 complement(3454900..3457158) 1 NC_008563.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3457158 parC 4491589 parC Escherichia coli APEC O1 DNA topoisomerase IV subunit A YP_854531.1 3454900 R 405955 CDS YP_854541.1 117625328 4491590 complement(3457296..3458903) 1 NC_008563.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein 3458903 ygiS 4491590 ygiS Escherichia coli APEC O1 hypothetical protein YP_854541.1 3457296 R 405955 CDS YP_854596.1 117625329 4491591 complement(3459012..3459494) 1 NC_008563.1 transcriptional regulator 3459494 ygiV 4491591 ygiV Escherichia coli APEC O1 transcriptional regulator YP_854596.1 3459012 R 405955 CDS YP_854599.1 117625330 4491592 complement(3459547..3459939) 1 NC_008563.1 hypothetical protein 3459939 ygiW 4491592 ygiW Escherichia coli APEC O1 hypothetical protein YP_854599.1 3459547 R 405955 CDS YP_854614.1 117625331 4491593 3460091..3460750 1 NC_008563.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3460750 ygiX 4491593 ygiX Escherichia coli APEC O1 DNA-binding transcriptional regulator QseB YP_854614.1 3460091 D 405955 CDS YP_854615.1 117625332 4491594 3460747..3462096 1 NC_008563.1 sensor protein QseC 3462096 qseC 4491594 qseC Escherichia coli APEC O1 sensor protein QseC YP_854615.1 3460747 D 405955 CDS YP_854619.1 117625333 4491595 complement(3462142..3462474) 1 NC_008563.1 hypothetical protein 3462474 4491595 APECO1_3394 Escherichia coli APEC O1 hypothetical protein YP_854619.1 3462142 R 405955 CDS YP_854628.1 117625334 4491596 complement(3462481..3463191) 1 NC_008563.1 hypothetical protein 3463191 4491596 APECO1_3393 Escherichia coli APEC O1 hypothetical protein YP_854628.1 3462481 R 405955 CDS YP_854630.1 117625335 4495011 complement(3463194..3463673) 1 NC_008563.1 hypothetical protein 3463673 4495011 APECO1_3392 Escherichia coli APEC O1 hypothetical protein YP_854630.1 3463194 R 405955 CDS YP_854632.1 117625336 4495012 3463923..3464504 1 NC_008563.1 modulator of drug activity B 3464504 mdaB 4495012 mdaB Escherichia coli APEC O1 modulator of drug activity B YP_854632.1 3463923 D 405955 CDS YP_854641.1 117625338 4495014 complement(3464894..3465781) 1 NC_008563.1 phosphosugar isomerase 3465781 4495014 APECO1_3389 Escherichia coli APEC O1 phosphosugar isomerase YP_854641.1 3464894 R 405955 CDS YP_854644.1 117625339 4495015 complement(3465778..3466785) 1 NC_008563.1 iron ABC transporter substrate-binding protein 3466785 4495015 APECO1_3388 Escherichia coli APEC O1 iron ABC transporter substrate-binding protein YP_854644.1 3465778 R 405955 CDS YP_854652.1 117625340 4495016 complement(3466736..3467785) 1 NC_008563.1 iron ABC transporter permease 3467785 4495016 APECO1_3387 Escherichia coli APEC O1 iron ABC transporter permease YP_854652.1 3466736 R 405955 CDS YP_854655.1 117625341 4495017 complement(3467782..3468765) 1 NC_008563.1 iron ABC transporter permease 3468765 4495017 APECO1_3386 Escherichia coli APEC O1 iron ABC transporter permease YP_854655.1 3467782 R 405955 CDS YP_854656.1 117625342 4495018 complement(3468762..3469571) 1 NC_008563.1 ferric enterobactin transport ATP-binding protein FepC 3469571 fepC 4495018 fepC Escherichia coli APEC O1 ferric enterobactin transport ATP-binding protein FepC YP_854656.1 3468762 R 405955 CDS YP_854660.1 117625343 4495019 3469945..3472086 1 NC_008563.1 iron compound receptor 3472086 4495019 APECO1_3384 Escherichia coli APEC O1 iron compound receptor YP_854660.1 3469945 D 405955 CDS YP_854666.1 117625344 4495020 complement(3472150..3474042) 1 NC_008563.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3474042 parE 4495020 parE Escherichia coli APEC O1 DNA topoisomerase IV subunit B YP_854666.1 3472150 R 405955 CDS YP_854670.1 117625345 4495021 complement(3474071..3474652) 1 NC_008563.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 3474652 yqiA 4495021 yqiA Escherichia coli APEC O1 esterase YqiA YP_854670.1 3474071 R 405955 CDS YP_854771.1 117625346 4495022 complement(3474652..3475347) 1 NC_008563.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 3475347 icc 4495022 icc Escherichia coli APEC O1 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_854771.1 3474652 R 405955 CDS YP_854814.1 117625347 4495023 complement(3475504..3475926) 1 NC_008563.1 hypothetical protein 3475926 yqiB 4495023 yqiB Escherichia coli APEC O1 hypothetical protein YP_854814.1 3475504 R 405955 CDS YP_854822.1 117625348 4495024 complement(3475927..3476556) 1 NC_008563.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 3476556 nudF 4495024 nudF Escherichia coli APEC O1 ADP-ribose pyrophosphatase NudF YP_854822.1 3475927 R 405955 CDS YP_854844.1 117625349 4495025 3476755..3478242 1 NC_008563.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3478242 tolC 4495025 tolC Escherichia coli APEC O1 outer membrane channel protein YP_854844.1 3476755 D 405955 CDS YP_854846.1 117625350 4495026 3478357..3479061 1 NC_008563.1 hypothetical protein 3479061 4495026 APECO1_3377 Escherichia coli APEC O1 hypothetical protein YP_854846.1 3478357 D 405955 CDS YP_854849.1 117625351 4495027 3479067..3480227 1 NC_008563.1 synthetase/amidase 3480227 ygiC 4495027 ygiC Escherichia coli APEC O1 synthetase/amidase YP_854849.1 3479067 D 405955 CDS YP_854851.1 117625352 4495028 3480712..3482508 1 NC_008563.1 arylsulfate sulfotransferase 3482508 assT 4495028 assT Escherichia coli APEC O1 arylsulfate sulfotransferase YP_854851.1 3480712 D 405955 CDS YP_854974.1 117625353 4495029 3482526..3483194 1 NC_008563.1 disulfide isomerase 3483194 4495029 APECO1_3374 Escherichia coli APEC O1 disulfide isomerase YP_854974.1 3482526 D 405955 CDS YP_854977.1 117625354 4494526 3483209..3483880 1 NC_008563.1 disulfide oxidoreductase 3483880 4494526 APECO1_3373 Escherichia coli APEC O1 disulfide oxidoreductase YP_854977.1 3483209 D 405955 CDS YP_854981.1 117625355 4494527 complement(3483926..3484741) 1 NC_008563.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3484741 ygiD 4494527 ygiD Escherichia coli APEC O1 hypothetical protein YP_854981.1 3483926 R 405955 CDS YP_854983.1 117625356 4494528 3484857..3485630 1 NC_008563.1 zinc transporter ZupT 3485630 ygiE 4494528 ygiE Escherichia coli APEC O1 zinc transporter ZupT YP_854983.1 3484857 D 405955 CDS YP_855132.1 117625357 4494529 3486433..3486996 1 NC_008563.1 fimbrial protein 3486996 4494529 APECO1_3370 Escherichia coli APEC O1 fimbrial protein YP_855132.1 3486433 D 405955 CDS YP_855135.1 117625358 4494530 3487083..3489605 1 NC_008563.1 outer membrane usher protein YqiG 3489605 yqiG 4494530 yqiG Escherichia coli APEC O1 outer membrane usher protein YqiG YP_855135.1 3487083 D 405955 CDS YP_855137.1 117625359 4494531 3489612..3490361 1 NC_008563.1 periplasmic chaperone YqiH 3490361 yqiH 4494531 yqiH Escherichia coli APEC O1 periplasmic chaperone YqiH YP_855137.1 3489612 D 405955 CDS YP_855140.1 117625360 4494532 3490358..3491407 1 NC_008563.1 Yqi fimbrial adhesin 3491407 4494532 APECO1_3367 Escherichia coli APEC O1 Yqi fimbrial adhesin YP_855140.1 3490358 D 405955 CDS YP_855141.1 117625361 4494533 complement(3491461..3492114) 1 NC_008563.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3492114 ribB 4494533 ribB Escherichia coli APEC O1 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_855141.1 3491461 R 405955 CDS YP_855145.1 117625362 4494534 3492428..3492787 1 NC_008563.1 hypothetical protein 3492787 yqiC 4494534 yqiC Escherichia coli APEC O1 hypothetical protein YP_855145.1 3492428 D 405955 CDS YP_855154.1 117625363 4494535 3493292..3493921 1 NC_008563.1 hypothetical protein 3493921 yqiJ 4494535 yqiJ Escherichia coli APEC O1 hypothetical protein YP_855154.1 3493292 D 405955 CDS YP_855184.1 117625364 4494536 3493948..3495609 1 NC_008563.1 hypothetical protein 3495609 yqiK 4494536 yqiK Escherichia coli APEC O1 hypothetical protein YP_855184.1 3493948 D 405955 CDS YP_855187.1 117625365 4494537 complement(3496028..3497461) 1 NC_008563.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3497461 rfaE 4494537 rfaE Escherichia coli APEC O1 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_855187.1 3496028 R 405955 CDS YP_855254.1 117625366 4494538 complement(3497509..3500421) 1 NC_008563.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3500421 glnE 4494538 glnE Escherichia coli APEC O1 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_855254.1 3497509 R 405955 CDS YP_855256.1 117625367 4494539 complement(3500372..3501673) 1 NC_008563.1 adenylate cyclase 3501673 ygiF 4494539 ygiF Escherichia coli APEC O1 adenylate cyclase YP_855256.1 3500372 R 405955 CDS YP_855259.1 117625368 4494540 3501915..3502535 1 NC_008563.1 signal transduction protein 3502535 htrG 4494540 htrG Escherichia coli APEC O1 signal transduction protein YP_855259.1 3501915 D 405955 CDS YP_855260.1 117625369 4494541 3502599..3503837 1 NC_008563.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3503837 cca 4494541 cca Escherichia coli APEC O1 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_855260.1 3502599 D 405955 CDS YP_855309.1 117625370 4494542 complement(3504025..3504846) 1 NC_008563.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3504846 uppP 4494542 uppP Escherichia coli APEC O1 undecaprenyl pyrophosphate phosphatase YP_855309.1 3504025 R 405955 CDS YP_855325.1 117625371 4494543 complement(3504937..3505305) 1 NC_008563.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3505305 folB 4494543 folB Escherichia coli APEC O1 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_855325.1 3504937 R 405955 CDS YP_855413.1 117625372 4494544 3505410..3506027 1 NC_008563.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3506027 ygiH 4494544 ygiH Escherichia coli APEC O1 glycerol-3-phosphate acyltransferase PlsY YP_855413.1 3505410 D 405955 CDS YP_855415.1 117625373 4494545 complement(3506040..3507026) 1 NC_008563.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3507026 4494545 APECO1_3354 Escherichia coli APEC O1 transcriptional activator TtdR YP_855415.1 3506040 R 405955 CDS YP_855419.1 117625374 4492017 3507179..3508090 1 NC_008563.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3508090 ttdA 4492017 ttdA Escherichia coli APEC O1 tartrate dehydratase subunit alpha YP_855419.1 3507179 D 405955 CDS YP_855432.1 117625375 4492018 3508087..3508692 1 NC_008563.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3508692 ttdB 4492018 ttdB Escherichia coli APEC O1 L(+)-tartrate dehydratase subunit beta YP_855432.1 3508087 D 405955 CDS YP_855434.1 117625376 4492019 3508740..3510203 1 NC_008563.1 tartrate:succinate antiporter 3510203 ygjE 4492019 ygjE Escherichia coli APEC O1 tartrate:succinate antiporter YP_855434.1 3508740 D 405955 CDS YP_855494.1 117625377 4492020 complement(3510246..3511259) 1 NC_008563.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3511259 ygjD 4492020 ygjD Escherichia coli APEC O1 DNA-binding/iron metalloprotein/AP endonuclease YP_855494.1 3510246 R 405955 CDS YP_855495.1 117625378 4492021 3511823..3513568 1 NC_008563.1 synthesizes RNA primers at the replication forks; DNA primase 3513568 dnaG 4492021 dnaG Escherichia coli APEC O1 DNA primase YP_855495.1 3511823 D 405955 CDS YP_855524.1 117625379 4492022 3513763..3515604 1 NC_008563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3515604 rpoD 4492022 rpoD Escherichia coli APEC O1 RNA polymerase sigma factor RpoD YP_855524.1 3513763 D 405955 CDS YP_855530.1 117625380 4492023 complement(3515683..3516189) 1 NC_008563.1 G/U mismatch-specific DNA glycosylase 3516189 ygjF 4492023 ygjF Escherichia coli APEC O1 G/U mismatch-specific DNA glycosylase YP_855530.1 3515683 R 405955 CDS YP_855628.1 117625381 4492024 complement(3516443..3517207) 1 NC_008563.1 siderophore interacting protein 3517207 yqjH 4492024 yqjH Escherichia coli APEC O1 siderophore interacting protein YP_855628.1 3516443 R 405955 CDS YP_858705.1 117625382 4492025 3517484..3518107 1 NC_008563.1 hypothetical protein 3518107 yqjI 4492025 yqjI Escherichia coli APEC O1 hypothetical protein YP_858705.1 3517484 D 405955 CDS YP_858706.1 117625383 4492026 complement(3518261..3519781) 1 NC_008563.1 aerotaxis sensor receptor, flavoprotein 3519781 aer 4492026 aer Escherichia coli APEC O1 aerotaxis sensor receptor, flavoprotein YP_858706.1 3518261 R 405955 CDS YP_858707.1 117625384 4492027 3520088..3521578 1 NC_008563.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3521578 ygjG 4492027 ygjG Escherichia coli APEC O1 putrescine--2-oxoglutarate aminotransferase YP_858707.1 3520088 D 405955 CDS YP_858709.1 117625386 4492029 3522171..3523154 1 NC_008563.1 DNA-binding transcriptional repressor EbgR 3523154 ebgR 4492029 ebgR Escherichia coli APEC O1 DNA-binding transcriptional repressor EbgR YP_858709.1 3522171 D 405955 CDS YP_858710.1 117625387 4492030 3523302..3526430 1 NC_008563.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3526430 ebgA 4492030 ebgA Escherichia coli APEC O1 cryptic beta-D-galactosidase subunit alpha YP_858710.1 3523302 D 405955 CDS YP_858711.1 117625388 4492031 3526427..3526876 1 NC_008563.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3526876 ebgC 4492031 ebgC Escherichia coli APEC O1 cryptic beta-D-galactosidase subunit beta YP_858711.1 3526427 D 405955 CDS YP_858712.1 117625389 4492032 3526939..3528372 1 NC_008563.1 oxidoreductase 3528372 ygjI 4492032 ygjI Escherichia coli APEC O1 oxidoreductase YP_858712.1 3526939 D 405955 CDS YP_858713.1 117625390 4492033 3528506..3529576 1 NC_008563.1 hypothetical protein 3529576 ygjJ 4492033 ygjJ Escherichia coli APEC O1 hypothetical protein YP_858713.1 3528506 D 405955 CDS YP_858714.1 117625391 4492034 3529593..3531944 1 NC_008563.1 glycosyl hydrolase 3531944 ygjK 4492034 ygjK Escherichia coli APEC O1 glycosyl hydrolase YP_858714.1 3529593 D 405955 CDS YP_858715.1 117625392 4492035 3532115..3534133 1 NC_008563.1 NADPH 2,4-dienoyl-CoA reductase 3534133 ygjL 4492035 ygjL Escherichia coli APEC O1 NADPH 2,4-dienoyl-CoA reductase YP_858715.1 3532115 D 405955 CDS YP_858716.1 117625393 4494991 complement(3534251..3535387) 1 NC_008563.1 ribosomal RNA small subunit methyltransferase D 3535387 ygjO 4494991 ygjO Escherichia coli APEC O1 ribosomal RNA small subunit methyltransferase D YP_858716.1 3534251 R 405955 CDS YP_858717.1 117625394 4494992 3536052..3536744 1 NC_008563.1 hypothetical protein 3536744 ygjQ 4494992 ygjQ Escherichia coli APEC O1 hypothetical protein YP_858717.1 3536052 D 405955 CDS YP_858718.1 117625395 4494993 3536805..3537809 1 NC_008563.1 oxidoreductase 3537809 ygjR 4494993 ygjR Escherichia coli APEC O1 oxidoreductase YP_858718.1 3536805 D 405955 CDS YP_858719.1 117625396 4494994 3538092..3539057 1 NC_008563.1 hypothetical protein 3539057 ygjT 4494994 ygjT Escherichia coli APEC O1 hypothetical protein YP_858719.1 3538092 D 405955 CDS YP_858720.1 117625397 4494995 3539381..3540625 1 NC_008563.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3540625 ygjU 4494995 ygjU Escherichia coli APEC O1 serine/threonine transporter SstT YP_858720.1 3539381 D 405955 CDS YP_858721.1 117625398 4494996 complement(3540629..3541180) 1 NC_008563.1 hypothetical protein 3541180 ygjV 4494996 ygjV Escherichia coli APEC O1 hypothetical protein YP_858721.1 3540629 R 405955 CDS YP_858722.1 117625399 4494997 complement(3541263..3542750) 1 NC_008563.1 altronate hydrolase 3542750 uxaA 4494997 uxaA Escherichia coli APEC O1 altronate hydrolase YP_858722.1 3541263 R 405955 CDS YP_858723.1 117625400 4494998 complement(3542765..3544177) 1 NC_008563.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3544177 uxaC 4494998 uxaC Escherichia coli APEC O1 glucuronate isomerase YP_858723.1 3542765 R 405955 CDS YP_858724.1 117625401 4494999 3544540..3545958 1 NC_008563.1 hexuronate transporter ExuT 3545958 exuT 4494999 exuT Escherichia coli APEC O1 hexuronate transporter ExuT YP_858724.1 3544540 D 405955 CDS YP_858725.1 117625402 4495000 3546073..3546864 1 NC_008563.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3546864 exuR 4495000 exuR Escherichia coli APEC O1 DNA-binding transcriptional repressor ExuR YP_858725.1 3546073 D 405955 CDS YP_858726.1 117625403 4495001 3547209..3547871 1 NC_008563.1 hypothetical protein 3547871 4495001 APECO1_3324 Escherichia coli APEC O1 hypothetical protein YP_858726.1 3547209 D 405955 CDS YP_858727.1 117625404 4495002 3547875..3548258 1 NC_008563.1 hypothetical protein 3548258 yqjB 4495002 yqjB Escherichia coli APEC O1 hypothetical protein YP_858727.1 3547875 D 405955 CDS YP_858728.2 229775959 4495003 3548405..3548773 1 NC_008563.1 hypothetical protein 3548773 yqjC 4495003 yqjC Escherichia coli APEC O1 hypothetical protein YP_858728.2 3548405 D 405955 CDS YP_858729.1 117625406 4495004 3549050..3549523 1 NC_008563.1 hypothetical protein 3549523 4495004 APECO1_3321 Escherichia coli APEC O1 hypothetical protein YP_858729.1 3549050 D 405955 CDS YP_858730.1 117625407 4495005 3549471..3549812 1 NC_008563.1 hypothetical protein 3549812 yqjK 4495005 yqjK Escherichia coli APEC O1 hypothetical protein YP_858730.1 3549471 D 405955 CDS YP_858731.1 117625408 4495006 3549909..3550391 1 NC_008563.1 hypothetical protein 3550391 yqjF 4495006 yqjF Escherichia coli APEC O1 hypothetical protein YP_858731.1 3549909 D 405955 CDS YP_858732.1 117625409 4495007 3550461..3551447 1 NC_008563.1 glutathione S-transferase 3551447 yqjG 4495007 yqjG Escherichia coli APEC O1 glutathione S-transferase YP_858732.1 3550461 D 405955 CDS YP_858733.1 117625410 4495008 3551730..3552098 1 NC_008563.1 cytochrome 3552098 yhaH 4495008 yhaH Escherichia coli APEC O1 cytochrome YP_858733.1 3551730 D 405955 CDS YP_858734.1 117625411 4495009 complement(3552132..3553028) 1 NC_008563.1 DNA-binding transcriptional regulator 3553028 yhaJ 4495009 yhaJ Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_858734.1 3552132 R 405955 CDS YP_858735.1 117625412 4495010 3553133..3553834 1 NC_008563.1 pirin-related protein 3553834 4495010 APECO1_3315 Escherichia coli APEC O1 pirin-related protein YP_858735.1 3553133 D 405955 CDS YP_858736.1 117625413 4491459 complement(3554153..3555463) 1 NC_008563.1 hypothetical protein 3555463 yhaM 4491459 yhaM Escherichia coli APEC O1 hypothetical protein YP_858736.1 3554153 R 405955 CDS YP_858737.1 117625414 4491460 complement(3555491..3556822) 1 NC_008563.1 amino acid permease 3556822 4491460 APECO1_3313 Escherichia coli APEC O1 amino acid permease YP_858737.1 3555491 R 405955 CDS YP_858738.1 117625415 4491461 complement(3557097..3558467) 1 NC_008563.1 L-serine dehydratase 3558467 tdcG 4491461 tdcG Escherichia coli APEC O1 L-serine dehydratase YP_858738.1 3557097 R 405955 CDS YP_858739.1 117625416 4491462 complement(3558533..3558970) 1 NC_008563.1 hypothetical protein 3558970 tdcF 4491462 tdcF Escherichia coli APEC O1 hypothetical protein YP_858739.1 3558533 R 405955 CDS YP_858740.1 117625417 4491463 complement(3558936..3561230) 1 NC_008563.1 formate acetyltransferase 3 3561230 tdcE 4491463 tdcE Escherichia coli APEC O1 formate acetyltransferase 3 YP_858740.1 3558936 R 405955 CDS YP_858741.1 117625418 4491464 complement(3561264..3562484) 1 NC_008563.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3562484 tdcD 4491464 tdcD Escherichia coli APEC O1 propionate/acetate kinase YP_858741.1 3561264 R 405955 CDS YP_858742.1 117625419 4491465 complement(3562498..3563829) 1 NC_008563.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3563829 tdcC 4491465 tdcC Escherichia coli APEC O1 threonine/serine transporter TdcC YP_858742.1 3562498 R 405955 CDS YP_858743.1 117625420 4491466 complement(3563851..3564840) 1 NC_008563.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3564840 tdcB 4491466 tdcB Escherichia coli APEC O1 threonine dehydratase YP_858743.1 3563851 R 405955 CDS YP_858744.1 117625421 4491467 complement(3564933..3565871) 1 NC_008563.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3565871 tdcA 4491467 tdcA Escherichia coli APEC O1 DNA-binding transcriptional activator TdcA YP_858744.1 3564933 R 405955 CDS YP_858745.1 117625422 4491468 3566061..3566405 1 NC_008563.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3566405 tdcR 4491468 tdcR Escherichia coli APEC O1 DNA-binding transcriptional activator TdcR YP_858745.1 3566061 D 405955 CDS YP_858746.1 117625423 4491469 3566924..3567451 1 NC_008563.1 hypothetical protein 3567451 4491469 APECO1_3304 Escherichia coli APEC O1 hypothetical protein YP_858746.1 3566924 D 405955 CDS YP_858747.1 117625424 4491470 complement(3567379..3568605) 1 NC_008563.1 glycerate kinase 3568605 garK 4491470 garK Escherichia coli APEC O1 glycerate kinase YP_858747.1 3567379 R 405955 CDS YP_858748.1 117625425 4491471 complement(3568621..3569520) 1 NC_008563.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3569520 garR 4491471 garR Escherichia coli APEC O1 tartronate semialdehyde reductase YP_858748.1 3568621 R 405955 CDS YP_858749.1 117625426 4491472 complement(3569541..3570311) 1 NC_008563.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3570311 garL 4491472 garL Escherichia coli APEC O1 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_858749.1 3569541 R 405955 CDS YP_858750.1 117625427 4491473 complement(3570327..3571661) 1 NC_008563.1 (D)-galactarate transporter 3571661 garP 4491473 garP Escherichia coli APEC O1 (D)-galactarate transporter YP_858750.1 3570327 R 405955 CDS YP_858751.1 117625428 4491474 3572036..3573607 1 NC_008563.1 D-galactarate dehydratase 3573607 garD 4491474 garD Escherichia coli APEC O1 D-galactarate dehydratase YP_858751.1 3572036 D 405955 CDS YP_858752.1 117625429 4491475 complement(3573659..3574483) 1 NC_008563.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; AgaR family transcriptional regulator 3574483 agaR 4491475 agaR Escherichia coli APEC O1 AgaR family transcriptional regulator YP_858752.1 3573659 R 405955 CDS YP_858753.1 117625430 4491476 3574732..3576012 1 NC_008563.1 tagatose 6-phosphate kinase 2 3576012 agaZ 4491476 agaZ Escherichia coli APEC O1 tagatose 6-phosphate kinase 2 YP_858753.1 3574732 D 405955 CDS YP_858754.1 117625431 4491477 3575999..3576508 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3576508 agaV 4491477 agaV Escherichia coli APEC O1 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_858754.1 3575999 D 405955 CDS YP_858755.1 117625432 4494756 3576519..3577298 1 NC_008563.1 phosphotransferase system enzyme subunit 3577298 4494756 APECO1_3295 Escherichia coli APEC O1 phosphotransferase system enzyme subunit YP_858755.1 3576519 D 405955 CDS YP_858756.1 117625433 4494757 3577288..3578166 1 NC_008563.1 PTS system N-acetylgalactosamine-specific transporter subunit IID 3578166 4494757 APECO1_3294 Escherichia coli APEC O1 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_858756.1 3577288 D 405955 CDS YP_858757.1 117625434 4494758 3578184..3578618 1 NC_008563.1 phosphotransferase system enzyme subunit 3578618 agaF 4494758 agaF Escherichia coli APEC O1 phosphotransferase system enzyme subunit YP_858757.1 3578184 D 405955 CDS YP_858758.1 117625435 4494759 3578594..3579748 1 NC_008563.1 N-acetylgalactosamine-6-phosphate deacetylase 3579748 4494759 APECO1_3292 Escherichia coli APEC O1 N-acetylgalactosamine-6-phosphate deacetylase YP_858758.1 3578594 D 405955 CDS YP_858759.1 117625436 4494760 3580097..3581251 1 NC_008563.1 tagatose-6-phosphate ketose/aldose isomerase 3581251 agaS 4494760 agaS Escherichia coli APEC O1 tagatose-6-phosphate ketose/aldose isomerase YP_858759.1 3580097 D 405955 CDS YP_858760.1 117625437 4494761 3581264..3582124 1 NC_008563.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3582124 kbaY 4494761 kbaY Escherichia coli APEC O1 tagatose-bisphosphate aldolase YP_858760.1 3581264 D 405955 CDS YP_858761.1 117625438 4494762 3582291..3582767 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3582767 agaB 4494762 agaB Escherichia coli APEC O1 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_858761.1 3582291 D 405955 CDS YP_858762.1 117625439 4494763 3582806..3583609 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3583609 agaC 4494763 agaC Escherichia coli APEC O1 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_858762.1 3582806 D 405955 CDS YP_858763.1 117625440 4494764 3583518..3584390 1 NC_008563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3584390 agaD 4494764 agaD Escherichia coli APEC O1 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_858763.1 3583518 D 405955 CDS YP_858764.1 117625441 4494765 3584391..3585158 1 NC_008563.1 galactosamine-6-phosphate isomerase 3585158 agaI 4494765 agaI Escherichia coli APEC O1 galactosamine-6-phosphate isomerase YP_858764.1 3584391 D 405955 CDS YP_858765.1 117625442 4494766 complement(3585208..3586071) 1 NC_008563.1 methyltransferase 3586071 yraL 4494766 yraL Escherichia coli APEC O1 methyltransferase YP_858765.1 3585208 R 405955 CDS YP_858766.1 117625443 4494767 3586136..3588172 1 NC_008563.1 hypothetical protein 3588172 yraM 4494767 yraM Escherichia coli APEC O1 hypothetical protein YP_858766.1 3586136 D 405955 CDS YP_858767.1 117625444 4494768 3588130..3588525 1 NC_008563.1 hypothetical protein 3588525 yraN 4494768 yraN Escherichia coli APEC O1 hypothetical protein YP_858767.1 3588130 D 405955 CDS YP_858768.1 117625445 4494769 3588545..3589135 1 NC_008563.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3589135 4494769 APECO1_3281 Escherichia coli APEC O1 DnaA initiator-associating protein DiaA YP_858768.1 3588545 D 405955 CDS YP_858769.1 117625446 4494770 3589145..3589720 1 NC_008563.1 periplasmic protein; hypothetical protein 3589720 yraP 4494770 yraP Escherichia coli APEC O1 hypothetical protein YP_858769.1 3589145 D 405955 CDS YP_858770.1 117625447 4494771 complement(3589833..3590873) 1 NC_008563.1 hypothetical protein 3590873 yraQ 4494771 yraQ Escherichia coli APEC O1 hypothetical protein YP_858770.1 3589833 R 405955 CDS YP_858771.1 117625448 4494772 complement(3590946..3591626) 1 NC_008563.1 hypothetical protein 3591626 4494772 APECO1_3278 Escherichia coli APEC O1 hypothetical protein YP_858771.1 3590946 R 405955 CDS YP_858772.1 117625449 4494773 3591709..3592227 1 NC_008563.1 hypothetical protein 3592227 4494773 APECO1_3277 Escherichia coli APEC O1 hypothetical protein YP_858772.1 3591709 D 405955 CDS YP_858773.1 117625450 4494774 complement(3592207..3592650) 1 NC_008563.1 hypothetical protein 3592650 yhbP 4494774 yhbP Escherichia coli APEC O1 hypothetical protein YP_858773.1 3592207 R 405955 CDS YP_858774.1 117625451 4494775 3592701..3593003 1 NC_008563.1 GIY-YIG nuclease superfamily protein 3593003 yhbQ 4494775 yhbQ Escherichia coli APEC O1 GIY-YIG nuclease superfamily protein YP_858774.1 3592701 D 405955 CDS YP_858775.1 117625452 4492103 complement(3592990..3593493) 1 NC_008563.1 acyltransferase 3593493 yhbS 4492103 yhbS Escherichia coli APEC O1 acyltransferase YP_858775.1 3592990 R 405955 CDS YP_858776.1 117625453 4492104 complement(3593487..3594011) 1 NC_008563.1 lipid carrier protein 3594011 yhbT 4492104 yhbT Escherichia coli APEC O1 lipid carrier protein YP_858776.1 3593487 R 405955 CDS YP_858777.1 117625454 4492105 3594220..3595215 1 NC_008563.1 collagenase 3595215 yhbU 4492105 yhbU Escherichia coli APEC O1 collagenase YP_858777.1 3594220 D 405955 CDS YP_858778.1 117625455 4492108 3595206..3596102 1 NC_008563.1 protease 3596102 yhbV 4492108 yhbV Escherichia coli APEC O1 protease YP_858778.1 3595206 D 405955 CDS YP_858779.1 117625456 4492109 3596183..3597190 1 NC_008563.1 hypothetical protein 3597190 yhbW 4492109 yhbW Escherichia coli APEC O1 hypothetical protein YP_858779.1 3596183 D 405955 CDS YP_858780.1 117625457 4492110 complement(3597308..3598552) 1 NC_008563.1 tryptophan transporter of high affinity; tryptophan permease 3598552 mtr 4492110 mtr Escherichia coli APEC O1 tryptophan permease YP_858780.1 3597308 R 405955 CDS YP_858781.1 117625458 4492111 complement(3598706..3600646) 1 NC_008563.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3600646 deaD 4492111 deaD Escherichia coli APEC O1 ATP-dependent RNA helicase DeaD YP_858781.1 3598706 R 405955 CDS YP_858782.1 117625459 4492112 complement(3600775..3601659) 1 NC_008563.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3601659 nlpI 4492112 nlpI Escherichia coli APEC O1 lipoprotein NlpI YP_858782.1 3600775 R 405955 CDS YP_858783.1 117625460 4492113 complement(3601768..3603972) 1 NC_008563.1 polynucleotide phosphorylase/polyadenylase 3603972 pnp 4492113 pnp Escherichia coli APEC O1 polynucleotide phosphorylase/polyadenylase YP_858783.1 3601768 R 405955 CDS YP_858784.1 117625461 4492114 complement(3604150..3604419) 1 NC_008563.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3604419 rpsO 4492114 rpsO Escherichia coli APEC O1 30S ribosomal protein S15 YP_858784.1 3604150 R 405955 CDS YP_858785.1 117625462 4492115 complement(3604568..3605512) 1 NC_008563.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3605512 truB 4492115 truB Escherichia coli APEC O1 tRNA pseudouridine synthase B YP_858785.1 3604568 R 405955 CDS YP_858786.1 117625463 4492116 complement(3605512..3605913) 1 NC_008563.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3605913 rbfA 4492116 rbfA Escherichia coli APEC O1 ribosome-binding factor A YP_858786.1 3605512 R 405955 CDS YP_858787.1 117625464 4492117 complement(3606077..3608749) 1 NC_008563.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3608749 infB 4492117 infB Escherichia coli APEC O1 translation initiation factor IF-2 YP_858787.1 3606077 R 405955 CDS YP_858788.1 117625465 4492118 complement(3608774..3610261) 1 NC_008563.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3610261 nusA 4492118 nusA Escherichia coli APEC O1 transcription elongation factor NusA YP_858788.1 3608774 R 405955 CDS YP_858789.2 229775958 4492119 complement(3610289..3610741) 1 NC_008563.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3610741 yhbC 4492119 yhbC Escherichia coli APEC O1 hypothetical protein YP_858789.2 3610289 R 405955 CDS YP_858790.1 117625467 4492120 3611372..3612715 1 NC_008563.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3612715 argG 4492120 argG Escherichia coli APEC O1 argininosuccinate synthase YP_858790.1 3611372 D 405955 CDS YP_858791.1 117625468 4492121 complement(3612723..3614366) 1 NC_008563.1 alkaline phosphatase I 3614366 yhbX 4492121 yhbX Escherichia coli APEC O1 alkaline phosphatase I YP_858791.1 3612723 R 405955 CDS YP_858792.1 117625469 4491324 complement(3614903..3615235) 1 NC_008563.1 preprotein translocase subunit SecG 3615235 secG 4491324 secG Escherichia coli APEC O1 preprotein translocase subunit SecG YP_858792.1 3614903 R 405955 CDS YP_858793.1 117625470 4491325 complement(3615463..3616800) 1 NC_008563.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3616800 glmM 4491325 glmM Escherichia coli APEC O1 phosphoglucosamine mutase YP_858793.1 3615463 R 405955 CDS YP_858794.1 117625471 4491326 complement(3616793..3617641) 1 NC_008563.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3617641 folP 4491326 folP Escherichia coli APEC O1 dihydropteroate synthase YP_858794.1 3616793 R 405955 CDS YP_858795.1 117625472 4491327 complement(3617731..3619665) 1 NC_008563.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3619665 hflB 4491327 hflB Escherichia coli APEC O1 ATP-dependent metalloprotease YP_858795.1 3617731 R 405955 CDS YP_858796.1 117625473 4491328 complement(3619765..3620394) 1 NC_008563.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 3620394 rrmJ 4491328 rrmJ Escherichia coli APEC O1 23S rRNA methyltransferase J YP_858796.1 3619765 R 405955 CDS YP_858797.1 117625474 4491329 complement(3620450..3620752) 1 NC_008563.1 hypothetical protein 3620752 4491329 APECO1_3252 Escherichia coli APEC O1 hypothetical protein YP_858797.1 3620450 R 405955 CDS YP_858798.1 117625475 4491330 complement(3620969..3621445) 1 NC_008563.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3621445 greA 4491330 greA Escherichia coli APEC O1 transcription elongation factor GreA YP_858798.1 3620969 R 405955 CDS YP_858799.1 117625476 4491331 3621693..3623126 1 NC_008563.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3623126 dacB 4491331 dacB Escherichia coli APEC O1 D-alanyl-D-alanine carboxypeptidase YP_858799.1 3621693 D 405955 CDS YP_858800.1 117625477 4491332 complement(3623167..3624339) 1 NC_008563.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3624339 obgE 4491332 obgE Escherichia coli APEC O1 GTPase ObgE YP_858800.1 3623167 R 405955 CDS YP_858801.1 117625478 4491333 complement(3624355..3625320) 1 NC_008563.1 hypothetical protein 3625320 yhbE 4491333 yhbE Escherichia coli APEC O1 hypothetical protein YP_858801.1 3624355 R 405955 CDS YP_858803.1 117625480 4491335 3626295..3627266 1 NC_008563.1 octaprenyl diphosphate synthase 3627266 ispB 4491335 ispB Escherichia coli APEC O1 octaprenyl diphosphate synthase YP_858803.1 3626295 D 405955 CDS YP_858804.1 117625481 4491336 3627499..3627777 1 NC_008563.1 regulatory factor of maltose metabolism; activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3627777 nlp 4491336 nlp Escherichia coli APEC O1 DNA-binding transcriptional regulator Nlp YP_858804.1 3627499 D 405955 CDS YP_858805.1 117625482 4491337 complement(3627825..3629084) 1 NC_008563.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3629084 murA 4491337 murA Escherichia coli APEC O1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_858805.1 3627825 R 405955 CDS YP_858806.1 117625483 4491338 complement(3629139..3629408) 1 NC_008563.1 DNA-binding transcriptional regulator 3629408 yrbA 4491338 yrbA Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_858806.1 3629139 R 405955 CDS YP_858807.1 117625484 4491339 complement(3629846..3630481) 1 NC_008563.1 hypothetical protein 3630481 yrbC 4491339 yrbC Escherichia coli APEC O1 hypothetical protein YP_858807.1 3629846 R 405955 CDS YP_858808.1 117625485 4491340 complement(3630500..3631051) 1 NC_008563.1 ABC-type organic solvent transporter 3631051 yrbD 4491340 yrbD Escherichia coli APEC O1 ABC-type organic solvent transporter YP_858808.1 3630500 R 405955 CDS YP_858809.1 117625486 4491341 complement(3631056..3631838) 1 NC_008563.1 toluene transporter subunit: permease component 3631838 yrbE 4491341 yrbE Escherichia coli APEC O1 toluene transporter subunit: permease component YP_858809.1 3631056 R 405955 CDS YP_858810.1 117625487 4491342 complement(3631846..3632655) 1 NC_008563.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein 3632655 yrbF 4491342 yrbF Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_858810.1 3631846 R 405955 CDS YP_858811.1 117625488 4491343 3632865..3633842 1 NC_008563.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3633842 yrbG 4491343 yrbG Escherichia coli APEC O1 calcium/sodium:proton antiporter YP_858811.1 3632865 D 405955 CDS YP_858812.1 117625489 4491382 3633856..3634842 1 NC_008563.1 D-arabinose 5-phosphate isomerase 3634842 kdsD 4491382 kdsD Escherichia coli APEC O1 D-arabinose 5-phosphate isomerase YP_858812.1 3633856 D 405955 CDS YP_858813.1 117625490 4491383 3634863..3635429 1 NC_008563.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3635429 yrbI 4491383 yrbI Escherichia coli APEC O1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_858813.1 3634863 D 405955 CDS YP_858814.1 117625491 4491384 3635426..3636001 1 NC_008563.1 hypothetical protein 3636001 4491384 APECO1_3236 Escherichia coli APEC O1 hypothetical protein YP_858814.1 3635426 D 405955 CDS YP_858815.1 117625492 4491385 3635970..3636527 1 NC_008563.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3636527 yhbN 4491385 yhbN Escherichia coli APEC O1 lipopolysaccharide transport periplasmic protein LptA YP_858815.1 3635970 D 405955 CDS YP_858816.1 117625493 4491386 3636534..3637259 1 NC_008563.1 ABC transporter ATP-binding protein 3637259 yhbG 4491386 yhbG Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_858816.1 3636534 D 405955 CDS YP_858817.1 117625494 4491387 3637307..3638740 1 NC_008563.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3638740 rpoN 4491387 rpoN Escherichia coli APEC O1 RNA polymerase factor sigma-54 YP_858817.1 3637307 D 405955 CDS YP_858818.1 117625495 4491388 3638763..3639050 1 NC_008563.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3639050 yhbH 4491388 yhbH Escherichia coli APEC O1 sigma(54) modulation protein YP_858818.1 3638763 D 405955 CDS YP_858819.1 117625496 4491389 3639144..3639659 1 NC_008563.1 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3639659 ptsN 4491389 ptsN Escherichia coli APEC O1 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_858819.1 3639144 D 405955 CDS YP_858820.1 117625497 4491390 3639705..3640559 1 NC_008563.1 hypothetical protein 3640559 4491390 APECO1_3230 Escherichia coli APEC O1 hypothetical protein YP_858820.1 3639705 D 405955 CDS YP_858821.1 117625498 4491391 3640556..3640828 1 NC_008563.1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3640828 ptsO 4491391 ptsO Escherichia coli APEC O1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_858821.1 3640556 D 405955 CDS YP_858822.1 117625499 4491392 3641042..3641674 1 NC_008563.1 hypothetical protein 3641674 yrbL 4491392 yrbL Escherichia coli APEC O1 hypothetical protein YP_858822.1 3641042 D 405955 CDS YP_858823.1 117625500 4491393 complement(3641671..3642399) 1 NC_008563.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3642399 mtgA 4491393 mtgA Escherichia coli APEC O1 monofunctional biosynthetic peptidoglycan transglycosylase YP_858823.1 3641671 R 405955 CDS YP_858824.1 117625501 4491394 complement(3642396..3643049) 1 NC_008563.1 isoprenoid biosynthesis protein with amidotransferase-like domain 3643049 yhbL 4491394 yhbL Escherichia coli APEC O1 isoprenoid biosynthesis protein with amidotransferase-like domain YP_858824.1 3642396 R 405955 CDS YP_858825.1 117625502 4491395 complement(3643279..3645615) 1 NC_008563.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3645615 arcB 4491395 arcB Escherichia coli APEC O1 aerobic respiration control sensor protein ArcB YP_858825.1 3643279 R 405955 CDS YP_858826.1 117625503 4491396 complement(3645711..3646640) 1 NC_008563.1 Fe-S oxidoreductase 3646640 yhcC 4491396 yhcC Escherichia coli APEC O1 Fe-S oxidoreductase YP_858826.1 3645711 R 405955 CDS YP_858827.1 117625504 4491397 3647207..3651775 1 NC_008563.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3651775 gltB 4491397 gltB Escherichia coli APEC O1 glutamate synthase subunit alpha YP_858827.1 3647207 D 405955 CDS YP_858828.1 117625505 4491398 3651788..3653206 1 NC_008563.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3653206 gltD 4491398 gltD Escherichia coli APEC O1 glutamate synthase subunit beta YP_858828.1 3651788 D 405955 CDS YP_858829.1 117625506 4491399 complement(3653274..3653738) 1 NC_008563.1 hypothetical protein 3653738 yhcH 4491399 yhcH Escherichia coli APEC O1 hypothetical protein YP_858829.1 3653274 R 405955 CDS YP_858830.1 117625507 4491400 complement(3653735..3654610) 1 NC_008563.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3654610 nanK 4491400 nanK Escherichia coli APEC O1 N-acetylmannosamine kinase YP_858830.1 3653735 R 405955 CDS YP_858831.1 117625508 4494716 complement(3654607..3655296) 1 NC_008563.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3655296 nanE 4494716 nanE Escherichia coli APEC O1 N-acetylmannosamine-6-phosphate 2-epimerase YP_858831.1 3654607 R 405955 CDS YP_858832.1 117625509 4494717 complement(3655344..3656864) 1 NC_008563.1 sialic acid transporter 3656864 nanT 4494717 nanT Escherichia coli APEC O1 sialic acid transporter YP_858832.1 3655344 R 405955 CDS YP_858833.1 117625510 4494718 complement(3656943..3657836) 1 NC_008563.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3657836 nanA 4494718 nanA Escherichia coli APEC O1 N-acetylneuraminate lyase YP_858833.1 3656943 R 405955 CDS YP_858834.1 117625511 4494719 complement(3657958..3658749) 1 NC_008563.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3658749 nanR 4494719 nanR Escherichia coli APEC O1 transcriptional regulator NanR YP_858834.1 3657958 R 405955 CDS YP_858835.1 117625512 4494720 complement(3658857..3659354) 1 NC_008563.1 ClpXP protease specificity-enhancing factor 3659354 sspB 4494720 sspB Escherichia coli APEC O1 ClpXP protease specificity-enhancing factor YP_858835.1 3658857 R 405955 CDS YP_858836.1 117625513 4494721 complement(3659360..3659998) 1 NC_008563.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3659998 sspA 4494721 sspA Escherichia coli APEC O1 stringent starvation protein A YP_858836.1 3659360 R 405955 CDS YP_858837.1 117625514 4494722 complement(3660393..3660785) 1 NC_008563.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3660785 rpsI 4494722 rpsI Escherichia coli APEC O1 30S ribosomal protein S9 YP_858837.1 3660393 R 405955 CDS YP_858838.1 117625515 4494723 complement(3660801..3661229) 1 NC_008563.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3661229 rplM 4494723 rplM Escherichia coli APEC O1 50S ribosomal protein L13 YP_858838.1 3660801 R 405955 CDS YP_858839.1 117625516 4494724 complement(3661449..3662576) 1 NC_008563.1 ATPase function; hypothetical protein 3662576 yhcM 4494724 yhcM Escherichia coli APEC O1 hypothetical protein YP_858839.1 3661449 R 405955 CDS YP_858840.1 117625517 4494725 3662819..3663229 1 NC_008563.1 hypothetical protein 3663229 4494725 APECO1_3211 Escherichia coli APEC O1 hypothetical protein YP_858840.1 3662819 D 405955 CDS YP_858841.1 117625518 4494726 3663322..3664689 1 NC_008563.1 serine endoprotease 3664689 degQ 4494726 degQ Escherichia coli APEC O1 serine endoprotease YP_858841.1 3663322 D 405955 CDS YP_858842.1 117625519 4494727 3664779..3665846 1 NC_008563.1 serine endoprotease 3665846 degS 4494727 degS Escherichia coli APEC O1 serine endoprotease YP_858842.1 3664779 D 405955 CDS YP_858843.1 117625520 4494728 complement(3665909..3666847) 1 NC_008563.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3666847 mdh 4494728 mdh Escherichia coli APEC O1 malate dehydrogenase YP_858843.1 3665909 R 405955 CDS YP_858844.1 117625521 4494729 3667282..3667752 1 NC_008563.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3667752 argR 4494729 argR Escherichia coli APEC O1 arginine repressor YP_858844.1 3667282 D 405955 CDS YP_858845.1 117625522 4494730 3668065..3668379 1 NC_008563.1 hypothetical protein 3668379 4494730 APECO1_3206 Escherichia coli APEC O1 hypothetical protein YP_858845.1 3668065 D 405955 CDS YP_858846.1 117625523 4494731 complement(3668434..3668706) 1 NC_008563.1 hypothetical protein 3668706 yhcO 4494731 yhcO Escherichia coli APEC O1 hypothetical protein YP_858846.1 3668434 R 405955 CDS YP_858847.1 117625524 4494732 complement(3668798..3670765) 1 NC_008563.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3670765 yhcP 4494732 yhcP Escherichia coli APEC O1 p-hydroxybenzoic acid efflux subunit AaeB YP_858847.1 3668798 R 405955 CDS YP_858848.1 117625525 4494733 complement(3670771..3671703) 1 NC_008563.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3671703 yhcQ 4494733 yhcQ Escherichia coli APEC O1 p-hydroxybenzoic acid efflux subunit AaeA YP_858848.1 3670771 R 405955 CDS YP_858849.2 229775957 4494734 complement(3671711..3671914) 1 NC_008563.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3671914 4494734 APECO1_3202 Escherichia coli APEC O1 hypothetical protein YP_858849.2 3671711 R 405955 CDS YP_858850.1 117625527 4494735 3672097..3673026 1 NC_008563.1 DNA-binding transcriptional regulator 3673026 aaeR 4494735 aaeR Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_858850.1 3672097 D 405955 CDS YP_858851.1 117625528 4493831 complement(3673154..3674599) 1 NC_008563.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3674599 tldD 4493831 tldD Escherichia coli APEC O1 protease TldD YP_858851.1 3673154 R 405955 CDS YP_858852.1 117625529 4493832 complement(3674755..3678555) 1 NC_008563.1 hypothetical protein 3678555 yhdP 4493832 yhdP Escherichia coli APEC O1 hypothetical protein YP_858852.1 3674755 R 405955 CDS YP_858853.1 117625530 4493833 complement(3678623..3680092) 1 NC_008563.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3680092 rng 4493833 rng Escherichia coli APEC O1 ribonuclease G YP_858853.1 3678623 R 405955 CDS YP_858854.1 117625531 4493834 complement(3680082..3680675) 1 NC_008563.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3680675 maf 4493834 maf Escherichia coli APEC O1 Maf-like protein YP_858854.1 3680082 R 405955 CDS YP_858855.1 117625532 4493835 complement(3680684..3681172) 1 NC_008563.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3681172 mreD 4493835 mreD Escherichia coli APEC O1 rod shape-determining protein MreD YP_858855.1 3680684 R 405955 CDS YP_858856.1 117625533 4493836 complement(3681172..3682275) 1 NC_008563.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3682275 mreC 4493836 mreC Escherichia coli APEC O1 rod shape-determining protein MreC YP_858856.1 3681172 R 405955 CDS YP_858857.1 117625534 4493837 complement(3682341..3683384) 1 NC_008563.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3683384 mreB 4493837 mreB Escherichia coli APEC O1 rod shape-determining protein MreB YP_858857.1 3682341 R 405955 CDS YP_858858.1 117625535 4493838 complement(3683689..3685629) 1 NC_008563.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3685629 yhdA 4493838 yhdA Escherichia coli APEC O1 regulatory protein CsrD YP_858858.1 3683689 R 405955 CDS YP_858859.1 117625536 4493839 3685781..3686755 1 NC_008563.1 oxidoreductase, Zn-dependent and NAD(P)-binding 3686755 yhdH 4493839 yhdH Escherichia coli APEC O1 oxidoreductase, Zn-dependent and NAD(P)-binding YP_858859.1 3685781 D 405955 CDS YP_858860.1 117625537 4493840 3687733..3688203 1 NC_008563.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3688203 accB 4493840 accB Escherichia coli APEC O1 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_858860.1 3687733 D 405955 CDS YP_858861.1 117625538 4493841 3688214..3689563 1 NC_008563.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3689563 accC 4493841 accC Escherichia coli APEC O1 acetyl-CoA carboxylase biotin carboxylase subunit YP_858861.1 3688214 D 405955 CDS YP_858862.1 117625539 4493842 complement(3689655..3690701) 1 NC_008563.1 hypothetical protein 3690701 4493842 APECO1_3189 Escherichia coli APEC O1 hypothetical protein YP_858862.1 3689655 R 405955 CDS YP_858863.1 117625540 4493843 complement(3690698..3691660) 1 NC_008563.1 ribokinase family sugar kinase 3691660 4493843 APECO1_3188 Escherichia coli APEC O1 ribokinase family sugar kinase YP_858863.1 3690698 R 405955 CDS YP_858864.1 117625541 4493844 complement(3691682..3692671) 1 NC_008563.1 ribose transport system permease RbsC 3692671 rbsC 4493844 rbsC Escherichia coli APEC O1 ribose transport system permease RbsC YP_858864.1 3691682 R 405955 CDS YP_858865.1 117625542 4493845 complement(3692672..3694171) 1 NC_008563.1 ribose transport ATP-binding protein RbsA 3694171 rbsA 4493845 rbsA Escherichia coli APEC O1 ribose transport ATP-binding protein RbsA YP_858865.1 3692672 R 405955 CDS YP_858866.1 117625543 4493846 complement(3694232..3695122) 1 NC_008563.1 ribose ABC transporter 3695122 4493846 APECO1_3185 Escherichia coli APEC O1 ribose ABC transporter YP_858866.1 3694232 R 405955 CDS YP_858867.1 117625544 4493847 complement(3695158..3696012) 1 NC_008563.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3696012 gatY 4493847 gatY Escherichia coli APEC O1 tagatose-bisphosphate aldolase YP_858867.1 3695158 R 405955 CDS YP_858868.1 117625545 4493848 3696353..3697183 1 NC_008563.1 DeoR family transcriptional regulator 3697183 4493848 APECO1_3183 Escherichia coli APEC O1 DeoR family transcriptional regulator YP_858868.1 3696353 D 405955 CDS YP_858869.1 117625546 4493849 3697140..3697790 1 NC_008563.1 hypothetical protein 3697790 4493849 APECO1_31822 Escherichia coli APEC O1 hypothetical protein YP_858869.1 3697140 D 405955 CDS YP_858870.1 117625547 4491869 3697869..3698150 1 NC_008563.1 hypothetical protein 3698150 4491869 APECO1_3182 Escherichia coli APEC O1 hypothetical protein YP_858870.1 3697869 D 405955 CDS YP_858871.1 117625548 4491870 3698225..3698485 1 NC_008563.1 hypothetical protein 3698485 yhdT 4491870 yhdT Escherichia coli APEC O1 hypothetical protein YP_858871.1 3698225 D 405955 CDS YP_858872.1 117625549 4491871 3698469..3699926 1 NC_008563.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3699926 panF 4491871 panF Escherichia coli APEC O1 sodium/panthothenate symporter YP_858872.1 3698469 D 405955 CDS YP_858873.1 117625550 4491872 3699938..3700819 1 NC_008563.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3700819 prmA 4491872 prmA Escherichia coli APEC O1 50S ribosomal protein L11 methyltransferase YP_858873.1 3699938 D 405955 CDS YP_858874.1 117625551 4491873 3701148..3702113 1 NC_008563.1 tRNA-dihydrouridine synthase B 3702113 dusB 4491873 dusB Escherichia coli APEC O1 tRNA-dihydrouridine synthase B YP_858874.1 3701148 D 405955 CDS YP_858875.1 117625552 4491874 3702139..3702435 1 NC_008563.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3702435 fis 4491874 fis Escherichia coli APEC O1 DNA-binding protein Fis YP_858875.1 3702139 D 405955 CDS YP_858876.1 117625553 4491875 3702523..3703407 1 NC_008563.1 methyltransferase 3703407 yhdJ 4491875 yhdJ Escherichia coli APEC O1 methyltransferase YP_858876.1 3702523 D 405955 CDS YP_858877.1 117625554 4491876 complement(3703673..3704335) 1 NC_008563.1 DNA-binding transcriptional regulator EnvR 3704335 envR 4491876 envR Escherichia coli APEC O1 DNA-binding transcriptional regulator EnvR YP_858877.1 3703673 R 405955 CDS YP_858878.1 117625555 4491877 3704734..3705891 1 NC_008563.1 acriflavine resistance protein E 3705891 acrE 4491877 acrE Escherichia coli APEC O1 acriflavine resistance protein E YP_858878.1 3704734 D 405955 CDS YP_858879.1 117625556 4491878 3705903..3709007 1 NC_008563.1 acriflavine resistance protein F 3709007 acrF 4491878 acrF Escherichia coli APEC O1 acriflavine resistance protein F YP_858879.1 3705903 D 405955 CDS YP_858880.1 117625557 4491879 3709912..3710937 1 NC_008563.1 periplasmic amino acid ABC transporter binding protein 3710937 yhdW 4491879 yhdW Escherichia coli APEC O1 periplasmic amino acid ABC transporter binding protein YP_858880.1 3709912 D 405955 CDS YP_858881.1 117625558 4491880 3710987..3712186 1 NC_008563.1 amino acid ABC transporter permease 3712186 yhdX 4491880 yhdX Escherichia coli APEC O1 amino acid ABC transporter permease YP_858881.1 3710987 D 405955 CDS YP_858882.1 117625559 4491881 3712193..3713299 1 NC_008563.1 transport system permease 3713299 yhdY 4491881 yhdY Escherichia coli APEC O1 transport system permease YP_858882.1 3712193 D 405955 CDS YP_858883.1 117625560 4491882 3713307..3714065 1 NC_008563.1 amino acid ABC transporter ATP-binding protein 3714065 yhdZ 4491882 yhdZ Escherichia coli APEC O1 amino acid ABC transporter ATP-binding protein YP_858883.1 3713307 D 405955 CDS YP_858886.1 117625563 4491885 3719736..3720506 1 NC_008563.1 hypothetical protein 3720506 4491885 APECO1_3166 Escherichia coli APEC O1 hypothetical protein YP_858886.1 3719736 D 405955 CDS YP_858887.1 117625564 4491886 complement(3720736..3721554) 1 NC_008563.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3721554 aroE 4491886 aroE Escherichia coli APEC O1 shikimate 5-dehydrogenase YP_858887.1 3720736 R 405955 CDS YP_858888.1 117625565 4491887 complement(3721559..3722176) 1 NC_008563.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 3722176 yrdC 4491887 yrdC Escherichia coli APEC O1 ribosome maturation factor YP_858888.1 3721559 R 405955 CDS YP_858889.1 117625566 4491888 complement(3722136..3722678) 1 NC_008563.1 DNA topoisomerase 3722678 yrdD 4491888 yrdD Escherichia coli APEC O1 DNA topoisomerase YP_858889.1 3722136 R 405955 CDS YP_858890.1 117625567 4491715 complement(3722707..3723180) 1 NC_008563.1 hypothetical protein 3723180 4491715 APECO1_3162 Escherichia coli APEC O1 hypothetical protein YP_858890.1 3722707 R 405955 CDS YP_858891.1 117625568 4491716 complement(3723152..3724276) 1 NC_008563.1 DNA protecting protein DprA 3724276 4491716 APECO1_3161 Escherichia coli APEC O1 DNA protecting protein DprA YP_858891.1 3723152 R 405955 CDS YP_858892.1 117625569 4491717 3724406..3724915 1 NC_008563.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3724915 def 4491717 def Escherichia coli APEC O1 peptide deformylase YP_858892.1 3724406 D 405955 CDS YP_858893.1 117625570 4491718 3724930..3725877 1 NC_008563.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3725877 fmt 4491718 fmt Escherichia coli APEC O1 methionyl-tRNA formyltransferase YP_858893.1 3724930 D 405955 CDS YP_858894.1 117625571 4491719 3725929..3727218 1 NC_008563.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3727218 sun 4491719 sun Escherichia coli APEC O1 16S rRNA methyltransferase B YP_858894.1 3725929 D 405955 CDS YP_858895.1 117625572 4491720 3727240..3728616 1 NC_008563.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3728616 trkA 4491720 trkA Escherichia coli APEC O1 potassium transporter peripheral membrane protein YP_858895.1 3727240 D 405955 CDS YP_858896.1 117625573 4491721 3728746..3729159 1 NC_008563.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3729159 mscL 4491721 mscL Escherichia coli APEC O1 large-conductance mechanosensitive channel YP_858896.1 3728746 D 405955 CDS YP_858897.1 117625574 4491722 complement(3729430..3729855) 1 NC_008563.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3729855 zntR 4491722 zntR Escherichia coli APEC O1 zinc-responsive transcriptional regulator YP_858897.1 3729430 R 405955 CDS YP_858898.1 117625575 4491723 complement(3729866..3730234) 1 NC_008563.1 hypothetical protein 3730234 yhdN 4491723 yhdN Escherichia coli APEC O1 hypothetical protein YP_858898.1 3729866 R 405955 CDS YP_858899.1 117625576 4491724 complement(3730341..3730724) 1 NC_008563.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3730724 rplQ 4491724 rplQ Escherichia coli APEC O1 50S ribosomal protein L17 YP_858899.1 3730341 R 405955 CDS YP_858900.1 117625577 4491725 complement(3730765..3731754) 1 NC_008563.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3731754 rpoA 4491725 rpoA Escherichia coli APEC O1 DNA-directed RNA polymerase subunit alpha YP_858900.1 3730765 R 405955 CDS YP_858901.1 117625578 4491726 complement(3731780..3732400) 1 NC_008563.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3732400 rpsD 4491726 rpsD Escherichia coli APEC O1 30S ribosomal protein S4 YP_858901.1 3731780 R 405955 CDS YP_858902.1 117625579 4491727 complement(3732434..3732823) 1 NC_008563.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3732823 rpsK 4491727 rpsK Escherichia coli APEC O1 30S ribosomal protein S11 YP_858902.1 3732434 R 405955 CDS YP_858903.1 117625580 4491728 complement(3732840..3733196) 1 NC_008563.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3733196 rpsM 4491728 rpsM Escherichia coli APEC O1 30S ribosomal protein S13 YP_858903.1 3732840 R 405955 CDS YP_858904.1 117625581 4491729 complement(3733491..3734822) 1 NC_008563.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3734822 secY 4491729 secY Escherichia coli APEC O1 preprotein translocase subunit SecY YP_858904.1 3733491 R 405955 CDS YP_858905.1 117625582 4491730 complement(3734830..3735264) 1 NC_008563.1 late assembly protein; 50S ribosomal protein L15 3735264 rplO 4491730 rplO Escherichia coli APEC O1 50S ribosomal protein L15 YP_858905.1 3734830 R 405955 CDS YP_858906.1 117625583 4491733 complement(3735451..3735954) 1 NC_008563.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3735954 rpsE 4491733 rpsE Escherichia coli APEC O1 30S ribosomal protein S5 YP_858906.1 3735451 R 405955 CDS YP_858907.1 117625584 4493722 complement(3735969..3736322) 1 NC_008563.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3736322 rplR 4493722 rplR Escherichia coli APEC O1 50S ribosomal protein L18 YP_858907.1 3735969 R 405955 CDS YP_858908.1 117625585 4493723 complement(3736332..3736865) 1 NC_008563.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3736865 rplF 4493723 rplF Escherichia coli APEC O1 50S ribosomal protein L6 YP_858908.1 3736332 R 405955 CDS YP_858909.1 117625586 4493724 complement(3736878..3737270) 1 NC_008563.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3737270 rpsH 4493724 rpsH Escherichia coli APEC O1 30S ribosomal protein S8 YP_858909.1 3736878 R 405955 CDS YP_858910.1 117625587 4493725 complement(3737304..3737609) 1 NC_008563.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3737609 rpsN 4493725 rpsN Escherichia coli APEC O1 30S ribosomal protein S14 YP_858910.1 3737304 R 405955 CDS YP_858911.1 117625588 4493726 complement(3737624..3738163) 1 NC_008563.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3738163 rplE 4493726 rplE Escherichia coli APEC O1 50S ribosomal protein L5 YP_858911.1 3737624 R 405955 CDS YP_858912.1 117625589 4493727 complement(3738178..3738492) 1 NC_008563.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3738492 rplX 4493727 rplX Escherichia coli APEC O1 50S ribosomal protein L24 YP_858912.1 3738178 R 405955 CDS YP_858913.1 117625590 4493728 complement(3738503..3738874) 1 NC_008563.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3738874 rplN 4493728 rplN Escherichia coli APEC O1 50S ribosomal protein L14 YP_858913.1 3738503 R 405955 CDS YP_858914.1 117625591 4493729 complement(3739039..3739293) 1 NC_008563.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3739293 rpsQ 4493729 rpsQ Escherichia coli APEC O1 30S ribosomal protein S17 YP_858914.1 3739039 R 405955 CDS YP_858915.1 117625592 4493730 complement(3739484..3739894) 1 NC_008563.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3739894 rplP 4493730 rplP Escherichia coli APEC O1 50S ribosomal protein L16 YP_858915.1 3739484 R 405955 CDS YP_858916.1 117625593 4493731 complement(3739907..3740608) 1 NC_008563.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3740608 rpsC 4493731 rpsC Escherichia coli APEC O1 30S ribosomal protein S3 YP_858916.1 3739907 R 405955 CDS YP_858917.1 117625594 4493732 complement(3740626..3740958) 1 NC_008563.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3740958 rplV 4493732 rplV Escherichia coli APEC O1 50S ribosomal protein L22 YP_858917.1 3740626 R 405955 CDS YP_858918.1 117625595 4493733 complement(3740973..3741251) 1 NC_008563.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3741251 rpsS 4493733 rpsS Escherichia coli APEC O1 30S ribosomal protein S19 YP_858918.1 3740973 R 405955 CDS YP_858919.1 117625596 4494796 complement(3741268..3742089) 1 NC_008563.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3742089 rplB 4494796 rplB Escherichia coli APEC O1 50S ribosomal protein L2 YP_858919.1 3741268 R 405955 CDS YP_858920.1 117625597 4494797 complement(3742406..3743011) 1 NC_008563.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3743011 rplD 4494797 rplD Escherichia coli APEC O1 50S ribosomal protein L4 YP_858920.1 3742406 R 405955 CDS YP_858921.1 117625598 4494798 complement(3743022..3743651) 1 NC_008563.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3743651 rplC 4494798 rplC Escherichia coli APEC O1 50S ribosomal protein L3 YP_858921.1 3743022 R 405955 CDS YP_858922.1 117625599 4494799 complement(3743684..3743995) 1 NC_008563.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3743995 rpsJ 4494799 rpsJ Escherichia coli APEC O1 30S ribosomal protein S10 YP_858922.1 3743684 R 405955 CDS YP_858923.1 117625600 4494800 complement(3744654..3745229) 1 NC_008563.1 general secretion pathway protein A 3745229 yheD 4494800 yheD Escherichia coli APEC O1 general secretion pathway protein A YP_858923.1 3744654 R 405955 CDS YP_858924.1 117625601 4494801 complement(3745160..3745831) 1 NC_008563.1 general secretion pathway protein A 3745831 yheD 4494801 yheD Escherichia coli APEC O1 general secretion pathway protein A YP_858924.1 3745160 R 405955 CDS YP_858925.1 117625602 4494802 3746321..3747136 1 NC_008563.1 general secretion pathway protein C 3747136 hofC 4494802 hofC Escherichia coli APEC O1 general secretion pathway protein C YP_858925.1 3746321 D 405955 CDS YP_858926.1 117625603 4494803 3747108..3749072 1 NC_008563.1 general secretion pathway protein D 3749072 hofD 4494803 hofD Escherichia coli APEC O1 general secretion pathway protein D YP_858926.1 3747108 D 405955 CDS YP_858927.1 117625604 4494804 3749580..3750563 1 NC_008563.1 general secretion pathway protein E 3750563 hofE 4494804 hofE Escherichia coli APEC O1 general secretion pathway protein E YP_858927.1 3749580 D 405955 CDS YP_858928.1 117625605 4494805 3750560..3751756 1 NC_008563.1 general secretion pathway protein F 3751756 hofF 4494805 hofF Escherichia coli APEC O1 general secretion pathway protein F YP_858928.1 3750560 D 405955 CDS YP_858929.1 117625606 4494806 3751766..3752203 1 NC_008563.1 general secretion pathway protein G 3752203 hofG 4494806 hofG Escherichia coli APEC O1 general secretion pathway protein G YP_858929.1 3751766 D 405955 CDS YP_858930.1 117625607 4494807 3752211..3752720 1 NC_008563.1 general secretion pathway protein H 3752720 hofH 4494807 hofH Escherichia coli APEC O1 general secretion pathway protein H YP_858930.1 3752211 D 405955 CDS YP_858931.1 117625608 4494808 3752678..3753112 1 NC_008563.1 general secretion pathway protein I 3753112 hofI 4494808 hofI Escherichia coli APEC O1 general secretion pathway protein I YP_858931.1 3752678 D 405955 CDS YP_858932.1 117625609 4494809 3753105..3753692 1 NC_008563.1 general secretion pathway protein J 3753692 hofJ 4494809 hofJ Escherichia coli APEC O1 general secretion pathway protein J YP_858932.1 3753105 D 405955 CDS YP_858933.1 117625610 4494810 3753685..3753975 1 NC_008563.1 general secretion pathway protein K 3753975 hofK 4494810 hofK Escherichia coli APEC O1 general secretion pathway protein K YP_858933.1 3753685 D 405955 CDS YP_858934.1 117625611 4494811 3754120..3754671 1 NC_008563.1 general secretion pathway protein K 3754671 hofK 4494811 hofK Escherichia coli APEC O1 general secretion pathway protein K YP_858934.1 3754120 D 405955 CDS YP_858935.1 117625612 4494812 3754686..3755849 1 NC_008563.1 general secretion pathway protein L 3755849 yheK 4494812 yheK Escherichia coli APEC O1 general secretion pathway protein L YP_858935.1 3754686 D 405955 CDS YP_858936.1 117625613 4494813 3755822..3756307 1 NC_008563.1 general secretion pathway protein M 3756307 pshM 4494813 pshM Escherichia coli APEC O1 general secretion pathway protein M YP_858936.1 3755822 D 405955 CDS YP_858937.1 117625614 4494814 3756307..3756984 1 NC_008563.1 type 4 prepilin-like proteins leader peptide processing enzyme 3756984 hofD 4494814 hofD Escherichia coli APEC O1 type 4 prepilin-like proteins leader peptide processing enzyme YP_858937.1 3756307 D 405955 CDS YP_858938.1 117625615 4494121 complement(3757013..3757489) 1 NC_008563.1 iron storage protein; bacterioferritin 3757489 bfr 4494121 bfr Escherichia coli APEC O1 bacterioferritin YP_858938.1 3757013 R 405955 CDS YP_858939.1 117625616 4494122 complement(3757924..3760581) 1 NC_008563.1 bifunctional chitinase/lysozyme 3760581 yheB 4494122 yheB Escherichia coli APEC O1 bifunctional chitinase/lysozyme YP_858939.1 3757924 R 405955 CDS YP_858940.2 162317569 4494123 complement(3760928..3762112) 1 NC_008563.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3762112 tufA 4494123 tufA Escherichia coli APEC O1 elongation factor Tu YP_858940.2 3760928 R 405955 CDS YP_858941.1 117625618 4494124 complement(3762183..3764297) 1 NC_008563.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3764297 fusA 4494124 fusA Escherichia coli APEC O1 elongation factor G YP_858941.1 3762183 R 405955 CDS YP_858942.1 117625619 4494125 complement(3764394..3764864) 1 NC_008563.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3764864 rpsG 4494125 rpsG Escherichia coli APEC O1 30S ribosomal protein S7 YP_858942.1 3764394 R 405955 CDS YP_858943.1 117625620 4494126 complement(3764961..3765335) 1 NC_008563.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3765335 rpsL 4494126 rpsL Escherichia coli APEC O1 30S ribosomal protein S12 YP_858943.1 3764961 R 405955 CDS YP_858944.1 117625621 4494127 complement(3765461..3765748) 1 NC_008563.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3765748 yheL 4494127 yheL Escherichia coli APEC O1 sulfur transfer complex subunit TusB YP_858944.1 3765461 R 405955 CDS YP_858945.1 117625622 4494128 complement(3765755..3766114) 1 NC_008563.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3766114 yheM 4494128 yheM Escherichia coli APEC O1 sulfur relay protein TusC YP_858945.1 3765755 R 405955 CDS YP_858946.1 117625623 4494129 complement(3766114..3766500) 1 NC_008563.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3766500 yheN 4494129 yheN Escherichia coli APEC O1 sulfur transfer complex subunit TusD YP_858946.1 3766114 R 405955 CDS YP_858947.1 117625624 4494130 complement(3766500..3767234) 1 NC_008563.1 hypothetical protein 3767234 yheO 4494130 yheO Escherichia coli APEC O1 hypothetical protein YP_858947.1 3766500 R 405955 CDS YP_858948.1 117625625 4494131 complement(3767389..3768201) 1 NC_008563.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3768201 fkpA 4494131 fkpA Escherichia coli APEC O1 FKBP-type peptidyl-prolyl cis-trans isomerase YP_858948.1 3767389 R 405955 CDS YP_858949.1 117625626 4494132 complement(3768689..3769279) 1 NC_008563.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3769279 slyD 4494132 slyD Escherichia coli APEC O1 FKBP-type peptidyl-prolyl cis-trans isomerase YP_858949.1 3768689 R 405955 CDS YP_858950.1 117625627 4494133 complement(3769584..3771389) 1 NC_008563.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3771389 kefB 4494133 kefB Escherichia coli APEC O1 glutathione-regulated potassium-efflux system protein KefB YP_858950.1 3769584 R 405955 CDS YP_858951.1 117625628 4494134 complement(3771389..3771943) 1 NC_008563.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3771943 yheR 4494134 yheR Escherichia coli APEC O1 glutathione-regulated potassium-efflux system ancillary protein KefG YP_858951.1 3771389 R 405955 CDS YP_858952.1 117625629 4494135 3772071..3773984 1 NC_008563.1 ABC transporter ATP-binding protein 3773984 yheS 4494135 yheS Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_858952.1 3772071 D 405955 CDS YP_858953.1 117625630 4494136 3773984..3775006 1 NC_008563.1 hydrolase 3775006 yheT 4494136 yheT Escherichia coli APEC O1 hydrolase YP_858953.1 3773984 D 405955 CDS YP_858954.1 117625631 4494137 3775272..3776141 1 NC_008563.1 phosphoribulokinase PrkB 3776141 prkB 4494137 prkB Escherichia coli APEC O1 phosphoribulokinase PrkB YP_858954.1 3775272 D 405955 CDS YP_858955.1 117625632 4494138 complement(3776196..3776600) 1 NC_008563.1 hypothetical protein 3776600 4494138 APECO1_3099 Escherichia coli APEC O1 hypothetical protein YP_858955.1 3776196 R 405955 CDS YP_858956.1 117625633 4494139 3776902..3777534 1 NC_008563.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3777534 crp 4494139 crp Escherichia coli APEC O1 cAMP-regulatory protein YP_858956.1 3776902 D 405955 CDS YP_858957.1 117625634 4493147 3777585..3779675 1 NC_008563.1 integral membrane protein; hypothetical protein 3779675 yhfK 4493147 yhfK Escherichia coli APEC O1 hypothetical protein YP_858957.1 3777585 D 405955 CDS YP_858958.1 117625635 4493148 complement(3779742..3780962) 1 NC_008563.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 3780962 argD 4493148 argD Escherichia coli APEC O1 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_858958.1 3779742 R 405955 CDS YP_858959.1 117625636 4493149 complement(3781048..3781611) 1 NC_008563.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3781611 pabA 4493149 pabA Escherichia coli APEC O1 para-aminobenzoate synthase component II YP_858959.1 3781048 R 405955 CDS YP_858960.1 117625637 4493150 complement(3781643..3782245) 1 NC_008563.1 cell filamentation protein Fic 3782245 fic 4493150 fic Escherichia coli APEC O1 cell filamentation protein Fic YP_858960.1 3781643 R 405955 CDS YP_858961.1 117625638 4493151 complement(3782507..3783079) 1 NC_008563.1 peptidyl-prolyl cis-trans isomerase A 3783079 ppiA 4493151 ppiA Escherichia coli APEC O1 peptidyl-prolyl cis-trans isomerase A YP_858961.1 3782507 R 405955 CDS YP_858962.1 117625639 4493152 3783349..3784530 1 NC_008563.1 hypothetical protein 3784530 yhfC 4493152 yhfC Escherichia coli APEC O1 hypothetical protein YP_858962.1 3783349 D 405955 CDS YP_858963.1 117625640 4493153 3784792..3787335 1 NC_008563.1 nitrite reductase, large subunit, NAD(P)H-binding 3787335 nirB 4493153 nirB Escherichia coli APEC O1 nitrite reductase, large subunit, NAD(P)H-binding YP_858963.1 3784792 D 405955 CDS YP_858964.1 117625641 4493154 3787332..3787658 1 NC_008563.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3787658 nirD 4493154 nirD Escherichia coli APEC O1 nitrite reductase small subunit YP_858964.1 3787332 D 405955 CDS YP_858965.1 117625642 4493155 3787784..3788590 1 NC_008563.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3788590 nirC 4493155 nirC Escherichia coli APEC O1 nitrite transporter NirC YP_858965.1 3787784 D 405955 CDS YP_858966.1 117625643 4493156 3788609..3789982 1 NC_008563.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3789982 cysG 4493156 cysG Escherichia coli APEC O1 siroheme synthase YP_858966.1 3788609 D 405955 CDS YP_858967.1 117625644 4493157 complement(3790509..3791594) 1 NC_008563.1 hypothetical protein 3791594 yhfS 4493157 yhfS Escherichia coli APEC O1 hypothetical protein YP_858967.1 3790509 R 405955 CDS YP_858968.1 117625645 4493158 complement(3791606..3792910) 1 NC_008563.1 hypothetical protein 3792910 yhfT 4493158 yhfT Escherichia coli APEC O1 hypothetical protein YP_858968.1 3791606 R 405955 CDS YP_858969.1 117625646 4493159 complement(3792922..3793275) 1 NC_008563.1 hypothetical protein 3793275 yhfU 4493159 yhfU Escherichia coli APEC O1 hypothetical protein YP_858969.1 3792922 R 405955 CDS YP_858970.1 117625647 4493160 complement(3793286..3794164) 1 NC_008563.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase 3794164 php 4493160 php Escherichia coli APEC O1 hydrolase YP_858970.1 3793286 R 405955 CDS YP_858971.1 117625648 4493161 complement(3794161..3795387) 1 NC_008563.1 mutase 3795387 yhfW 4493161 yhfW Escherichia coli APEC O1 mutase YP_858971.1 3794161 R 405955 CDS YP_858972.1 117625649 4493162 complement(3795388..3796551) 1 NC_008563.1 amino acid racemase 3796551 yhfX 4493162 yhfX Escherichia coli APEC O1 amino acid racemase YP_858972.1 3795388 R 405955 CDS YP_858973.1 117625650 4493163 complement(3796635..3796997) 1 NC_008563.1 hypothetical protein 3796997 yhfY 4493163 yhfY Escherichia coli APEC O1 hypothetical protein YP_858973.1 3796635 R 405955 CDS YP_858974.1 117625651 4493164 complement(3797014..3797919) 1 NC_008563.1 hypothetical protein 3797919 yhfZ 4493164 yhfZ Escherichia coli APEC O1 hypothetical protein YP_858974.1 3797014 R 405955 CDS YP_858975.1 117625652 4492162 complement(3798079..3799083) 1 NC_008563.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3799083 trpS 4492162 trpS Escherichia coli APEC O1 tryptophanyl-tRNA synthetase YP_858975.1 3798079 R 405955 CDS YP_858976.1 117625653 4492163 complement(3799076..3799834) 1 NC_008563.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3799834 gph 4492163 gph Escherichia coli APEC O1 phosphoglycolate phosphatase YP_858976.1 3799076 R 405955 CDS YP_858977.1 117625654 4492164 complement(3799827..3800504) 1 NC_008563.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3800504 rpe 4492164 rpe Escherichia coli APEC O1 ribulose-phosphate 3-epimerase YP_858977.1 3799827 R 405955 CDS YP_858978.1 117625655 4492165 complement(3800522..3801358) 1 NC_008563.1 DNA adenine methylase 3801358 dam 4492165 dam Escherichia coli APEC O1 DNA adenine methylase YP_858978.1 3800522 R 405955 CDS YP_858979.1 117625656 4492166 complement(3801465..3802751) 1 NC_008563.1 hypothetical protein 3802751 damX 4492166 damX Escherichia coli APEC O1 hypothetical protein YP_858979.1 3801465 R 405955 CDS YP_858980.1 117625657 4492167 complement(3802843..3803931) 1 NC_008563.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3803931 aroB 4492167 aroB Escherichia coli APEC O1 3-dehydroquinate synthase YP_858980.1 3802843 R 405955 CDS YP_858981.2 229775956 4492168 complement(3803988..3804509) 1 NC_008563.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3804509 aroK 4492168 aroK Escherichia coli APEC O1 shikimate kinase I YP_858981.2 3803988 R 405955 CDS YP_858982.1 117625659 4492169 complement(3804910..3806148) 1 NC_008563.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3806148 hofQ 4492169 hofQ Escherichia coli APEC O1 outer membrane porin HofQ YP_858982.1 3804910 R 405955 CDS YP_858983.1 117625660 4492170 complement(3806454..3806894) 1 NC_008563.1 hypothetical protein 3806894 yrfB 4492170 yrfB Escherichia coli APEC O1 hypothetical protein YP_858983.1 3806454 R 405955 CDS YP_858984.1 117625661 4492171 complement(3806878..3807417) 1 NC_008563.1 hypothetical protein 3807417 yrfC 4492171 yrfC Escherichia coli APEC O1 hypothetical protein YP_858984.1 3806878 R 405955 CDS YP_858985.1 117625662 4492172 complement(3807417..3808223) 1 NC_008563.1 hypothetical protein 3808223 yrfD 4492172 yrfD Escherichia coli APEC O1 hypothetical protein YP_858985.1 3807417 R 405955 CDS YP_858986.2 229775955 4492173 3808316..3810868 1 NC_008563.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3810868 mrcA 4492173 mrcA Escherichia coli APEC O1 peptidoglycan synthetase YP_858986.2 3808316 D 405955 CDS YP_858987.1 117625664 4492174 complement(3811034..3811594) 1 NC_008563.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3811594 nudE 4492174 nudE Escherichia coli APEC O1 ADP-ribose diphosphatase NudE YP_858987.1 3811034 R 405955 CDS YP_858988.1 117625665 4492175 3811914..3814049 1 NC_008563.1 protein IgaA-like membrane protein 3814049 yrfF 4492175 yrfF Escherichia coli APEC O1 protein IgaA-like membrane protein YP_858988.1 3811914 D 405955 CDS YP_858989.1 117625666 4492176 3814069..3814782 1 NC_008563.1 hydrolase 3814782 yrfG 4492176 yrfG Escherichia coli APEC O1 hydrolase YP_858989.1 3814069 D 405955 CDS YP_858990.1 117625667 4492177 3814793..3815194 1 NC_008563.1 ribosome-associated heat shock protein Hsp15 3815194 hslR 4492177 hslR Escherichia coli APEC O1 ribosome-associated heat shock protein Hsp15 YP_858990.1 3814793 D 405955 CDS YP_858991.1 117625668 4492178 3815213..3816097 1 NC_008563.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3816097 hslO 4492178 hslO Escherichia coli APEC O1 Hsp33-like chaperonin YP_858991.1 3815213 D 405955 CDS YP_858992.1 117625669 4492179 complement(3816160..3817884) 1 NC_008563.1 inner membrane transport protein 3817884 yhgE 4492179 yhgE Escherichia coli APEC O1 inner membrane transport protein YP_858992.1 3816160 R 405955 CDS YP_858993.1 117625670 4492180 3818263..3819885 1 NC_008563.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3819885 pckA 4492180 pckA Escherichia coli APEC O1 phosphoenolpyruvate carboxykinase YP_858993.1 3818263 D 405955 CDS YP_858994.1 117625671 4492181 complement(3819961..3821313) 1 NC_008563.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3821313 envZ 4492181 envZ Escherichia coli APEC O1 osmolarity sensor protein YP_858994.1 3819961 R 405955 CDS YP_858995.1 117625672 4492601 complement(3821310..3822029) 1 NC_008563.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3822029 ompR 4492601 ompR Escherichia coli APEC O1 osmolarity response regulator YP_858995.1 3821310 R 405955 CDS YP_858996.1 117625673 4492602 3822257..3822733 1 NC_008563.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3822733 greB 4492602 greB Escherichia coli APEC O1 transcription elongation factor GreB YP_858996.1 3822257 D 405955 CDS YP_858997.1 117625674 4492603 3822830..3825151 1 NC_008563.1 transcriptional accessory protein 3825151 yhgF 4492603 yhgF Escherichia coli APEC O1 transcriptional accessory protein YP_858997.1 3822830 D 405955 CDS YP_858998.1 117625675 4492604 3825823..3828156 1 NC_008563.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3828156 feoB 4492604 feoB Escherichia coli APEC O1 ferrous iron transport protein B YP_858998.1 3825823 D 405955 CDS YP_858999.1 117625676 4492605 3828606..3829499 1 NC_008563.1 hypothetical protein 3829499 yhgA 4492605 yhgA Escherichia coli APEC O1 hypothetical protein YP_858999.1 3828606 D 405955 CDS YP_859000.1 117625677 4492606 complement(3829719..3830489) 1 NC_008563.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3830489 bioH 4492606 bioH Escherichia coli APEC O1 carboxylesterase BioH YP_859000.1 3829719 R 405955 CDS YP_859001.1 117625678 4492607 3830479..3831210 1 NC_008563.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3831210 yhgH 4492607 yhgH Escherichia coli APEC O1 gluconate periplasmic binding protein YP_859001.1 3830479 D 405955 CDS YP_859002.1 117625679 4492608 3831269..3831844 1 NC_008563.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3831844 4492608 APECO1_3052 Escherichia coli APEC O1 DNA uptake protein YP_859002.1 3831269 D 405955 CDS YP_859003.1 117625680 4492609 3832205..3833521 1 NC_008563.1 high-affinity transport permease for gluconate 3833521 gntT 4492609 gntT Escherichia coli APEC O1 high-affinity transport permease for gluconate YP_859003.1 3832205 D 405955 CDS YP_859004.1 117625681 4492610 complement(3833566..3835650) 1 NC_008563.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3835650 malQ 4492610 malQ Escherichia coli APEC O1 4-alpha-glucanotransferase YP_859004.1 3833566 R 405955 CDS YP_859005.1 117625682 4492611 complement(3835660..3838053) 1 NC_008563.1 maltodextrin phosphorylase MalP 3838053 malP 4492611 malP Escherichia coli APEC O1 maltodextrin phosphorylase MalP YP_859005.1 3835660 R 405955 CDS YP_859006.1 117625683 4492612 3838676..3841381 1 NC_008563.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3841381 malT 4492612 malT Escherichia coli APEC O1 transcriptional regulator MalT YP_859006.1 3838676 D 405955 CDS YP_859007.1 117625684 4492613 complement(3841424..3842443) 1 NC_008563.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3842443 rtcA 4492613 rtcA Escherichia coli APEC O1 RNA 3'-terminal-phosphate cyclase YP_859007.1 3841424 R 405955 CDS YP_859008.1 117625685 4492614 complement(3842444..3843670) 1 NC_008563.1 hypothetical protein 3843670 rtcB 4492614 rtcB Escherichia coli APEC O1 hypothetical protein YP_859008.1 3842444 R 405955 CDS YP_859009.1 117625686 4492615 3843859..3845418 1 NC_008563.1 transcriptional regulatory protein RtcR 3845418 rtcR 4492615 rtcR Escherichia coli APEC O1 transcriptional regulatory protein RtcR YP_859009.1 3843859 D 405955 CDS YP_859010.1 117625687 4492616 complement(3845438..3846232) 1 NC_008563.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3846232 glpR 4492616 glpR Escherichia coli APEC O1 DNA-binding transcriptional repressor GlpR YP_859010.1 3845438 R 405955 CDS YP_859011.1 117625688 4492617 complement(3846213..3847043) 1 NC_008563.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3847043 glpG 4492617 glpG Escherichia coli APEC O1 intramembrane serine protease GlpG YP_859011.1 3846213 R 405955 CDS YP_859012.1 117625689 4492618 complement(3847088..3847414) 1 NC_008563.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3847414 glpE 4492618 glpE Escherichia coli APEC O1 thiosulfate sulfurtransferase YP_859012.1 3847088 R 405955 CDS YP_859013.1 117625690 4492619 3847604..3849109 1 NC_008563.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3849109 glpD 4492619 glpD Escherichia coli APEC O1 glycerol-3-phosphate dehydrogenase YP_859013.1 3847604 D 405955 CDS YP_859014.1 117625691 4492698 complement(3849163..3849768) 1 NC_008563.1 hypothetical protein 3849768 4492698 APECO1_3040 Escherichia coli APEC O1 hypothetical protein YP_859014.1 3849163 R 405955 CDS YP_859015.1 117625692 4492699 complement(3849771..3850538) 1 NC_008563.1 hypothetical protein 3850538 4492699 APECO1_3039 Escherichia coli APEC O1 hypothetical protein YP_859015.1 3849771 R 405955 CDS YP_859016.1 117625693 4492700 complement(3850541..3851251) 1 NC_008563.1 hypothetical protein 3851251 aufG 4492700 aufG Escherichia coli APEC O1 hypothetical protein YP_859016.1 3850541 R 405955 CDS YP_859017.1 117625694 4492701 complement(3851424..3852545) 1 NC_008563.1 fimbrial adhesin 3852545 4492701 APECO1_3037 Escherichia coli APEC O1 fimbrial adhesin YP_859017.1 3851424 R 405955 CDS YP_859018.1 117625695 4492702 complement(3852560..3852892) 1 NC_008563.1 Auf fimbrial chaperone AufF 3852892 aufF 4492702 aufF Escherichia coli APEC O1 Auf fimbrial chaperone AufF YP_859018.1 3852560 R 405955 CDS YP_859019.1 117625696 4492703 complement(3853030..3853368) 1 NC_008563.1 Auf fimbrial chaperone AufF 3853368 aufF 4492703 aufF Escherichia coli APEC O1 Auf fimbrial chaperone AufF YP_859019.1 3853030 R 405955 CDS YP_859020.1 117625697 4492704 complement(3853375..3853890) 1 NC_008563.1 Auf fimbriae minor subunit AufE 3853890 aufE 4492704 aufE Escherichia coli APEC O1 Auf fimbriae minor subunit AufE YP_859020.1 3853375 R 405955 CDS YP_859021.1 117625698 4492705 complement(3853835..3854407) 1 NC_008563.1 Auf fimbriae minor subunit AufD 3854407 aufD 4492705 aufD Escherichia coli APEC O1 Auf fimbriae minor subunit AufD YP_859021.1 3853835 R 405955 CDS YP_859022.1 117625699 4492706 complement(3854398..3856992) 1 NC_008563.1 outer membrane usher protein AufC 3856992 aufC 4492706 aufC Escherichia coli APEC O1 outer membrane usher protein AufC YP_859022.1 3854398 R 405955 CDS YP_859023.1 117625700 4492707 complement(3857029..3857808) 1 NC_008563.1 fimbrial chaperone protein 3857808 4492707 APECO1_3031 Escherichia coli APEC O1 fimbrial chaperone protein YP_859023.1 3857029 R 405955 CDS YP_859024.1 117625701 4492708 complement(3857882..3858586) 1 NC_008563.1 Auf fimbriae major subunit AufA 3858586 aufA 4492708 aufA Escherichia coli APEC O1 Auf fimbriae major subunit AufA YP_859024.1 3857882 R 405955 CDS YP_859025.1 117625702 4492709 complement(3859080..3861527) 1 NC_008563.1 glycogen phosphorylase GlgP 3861527 glgP 4492709 glgP Escherichia coli APEC O1 glycogen phosphorylase GlgP YP_859025.1 3859080 R 405955 CDS YP_859026.1 117625703 4492710 complement(3861546..3862979) 1 NC_008563.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3862979 glgA 4492710 glgA Escherichia coli APEC O1 glycogen synthase YP_859026.1 3861546 R 405955 CDS YP_859027.1 117625704 4492711 complement(3862979..3864310) 1 NC_008563.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3864310 glgC 4492711 glgC Escherichia coli APEC O1 glucose-1-phosphate adenylyltransferase YP_859027.1 3862979 R 405955 CDS YP_859028.1 117625705 4492712 complement(3864292..3866265) 1 NC_008563.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 3866265 glgX 4492712 glgX Escherichia coli APEC O1 glycogen debranching protein YP_859028.1 3864292 R 405955 CDS YP_859029.1 117625706 4492713 complement(3866262..3868448) 1 NC_008563.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3868448 glgB 4492713 glgB Escherichia coli APEC O1 glycogen branching protein YP_859029.1 3866262 R 405955 CDS YP_859030.1 117625707 4492714 complement(3868721..3869884) 1 NC_008563.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3869884 asd 4492714 asd Escherichia coli APEC O1 aspartate-semialdehyde dehydrogenase YP_859030.1 3868721 R 405955 CDS YP_859031.1 117625708 4492715 3870016..3870609 1 NC_008563.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3870609 yhgN 4492715 yhgN Escherichia coli APEC O1 dITP- and XTP- hydrolase YP_859031.1 3870016 D 405955 CDS YP_859032.1 117625709 4492716 complement(3870666..3871733) 1 NC_008563.1 gluconate transporter GntU, low affinity GNT 1 system 3871733 gntU 4492716 gntU Escherichia coli APEC O1 gluconate transporter GntU, low affinity GNT 1 system YP_859032.1 3870666 R 405955 CDS YP_859033.1 117625710 4492717 complement(3872013..3872501) 1 NC_008563.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 3872501 gntK 4492717 gntK Escherichia coli APEC O1 gluconate kinase YP_859033.1 3872013 R 405955 CDS YP_859034.1 117625711 4495191 complement(3872679..3873674) 1 NC_008563.1 DNA-binding transcriptional repressor 3873674 gntR 4495191 gntR Escherichia coli APEC O1 DNA-binding transcriptional repressor YP_859034.1 3872679 R 405955 CDS YP_859035.1 117625712 4495192 complement(3873767..3874462) 1 NC_008563.1 hypothetical protein 3874462 yhhW 4495192 yhhW Escherichia coli APEC O1 hypothetical protein YP_859035.1 3873767 R 405955 CDS YP_859036.1 117625713 4495193 complement(3874585..3875622) 1 NC_008563.1 dehydrogenase 3875622 yhhX 4495193 yhhX Escherichia coli APEC O1 dehydrogenase YP_859036.1 3874585 R 405955 CDS YP_859037.1 117625714 4495194 complement(3875679..3875933) 1 NC_008563.1 hypothetical protein 3875933 4495194 APECO1_3017 Escherichia coli APEC O1 hypothetical protein YP_859037.1 3875679 R 405955 CDS YP_859038.1 117625715 4495195 3875956..3876444 1 NC_008563.1 YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3876444 yhhY 4495195 yhhY Escherichia coli APEC O1 acetyltransferase YhhY YP_859038.1 3875956 D 405955 CDS YP_859039.1 117625716 4495196 3876680..3877480 1 NC_008563.1 hypothetical protein 3877480 yhhZ 4495196 yhhZ Escherichia coli APEC O1 hypothetical protein YP_859039.1 3876680 D 405955 CDS YP_859040.1 117625717 4495197 3877855..3878349 1 NC_008563.1 hypothetical protein 3878349 yrhA 4495197 yrhA Escherichia coli APEC O1 hypothetical protein YP_859040.1 3877855 D 405955 CDS YP_859041.1 117625718 4495198 3878799..3879083 1 NC_008563.1 hypothetical protein 3879083 yrhB 4495198 yrhB Escherichia coli APEC O1 hypothetical protein YP_859041.1 3878799 D 405955 CDS YP_859042.1 117625719 4495199 complement(3879121..3880854) 1 NC_008563.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3880854 ggt 4495199 ggt Escherichia coli APEC O1 gamma-glutamyltranspeptidase YP_859042.1 3879121 R 405955 CDS YP_859043.1 117625720 4495200 3880974..3881414 1 NC_008563.1 hypothetical protein 3881414 yhhA 4495200 yhhA Escherichia coli APEC O1 hypothetical protein YP_859043.1 3880974 D 405955 CDS YP_859044.1 117625721 4495201 complement(3881401..3882144) 1 NC_008563.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 3882144 ugpQ 4495201 ugpQ Escherichia coli APEC O1 glycerophosphodiester phosphodiesterase YP_859044.1 3881401 R 405955 CDS YP_859045.1 117625722 4495202 complement(3882141..3883211) 1 NC_008563.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3883211 ugpC 4495202 ugpC Escherichia coli APEC O1 glycerol-3-phosphate transporter ATP-binding subunit YP_859045.1 3882141 R 405955 CDS YP_859046.1 117625723 4495203 complement(3883213..3884058) 1 NC_008563.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3884058 ugpE 4495203 ugpE Escherichia coli APEC O1 glycerol-3-phosphate transporter membrane protein YP_859046.1 3883213 R 405955 CDS YP_859047.1 117625724 4495204 complement(3884055..3884942) 1 NC_008563.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3884942 ugpA 4495204 ugpA Escherichia coli APEC O1 glycerol-3-phosphate transporter permease YP_859047.1 3884055 R 405955 CDS YP_859048.1 117625725 4495205 complement(3885040..3886356) 1 NC_008563.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3886356 ugpB 4495205 ugpB Escherichia coli APEC O1 glycerol-3-phosphate transporter periplasmic binding protein YP_859048.1 3885040 R 405955 CDS YP_859049.1 117625726 4495206 complement(3886753..3887478) 1 NC_008563.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3887478 livF 4495206 livF Escherichia coli APEC O1 leucine/isoleucine/valine transporter ATP-binding subunit YP_859049.1 3886753 R 405955 CDS YP_859050.1 117625727 4495207 complement(3887468..3888235) 1 NC_008563.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3888235 livG 4495207 livG Escherichia coli APEC O1 leucine/isoleucine/valine transporter ATP-binding subunit YP_859050.1 3887468 R 405955 CDS YP_859051.1 117625728 4495208 complement(3888232..3889509) 1 NC_008563.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3889509 livM 4495208 livM Escherichia coli APEC O1 leucine/isoleucine/valine transporter permease subunit YP_859051.1 3888232 R 405955 CDS YP_859052.1 117625729 4495209 complement(3889506..3890432) 1 NC_008563.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3890432 livH 4495209 livH Escherichia coli APEC O1 branched-chain amino acid transporter permease subunit LivH YP_859052.1 3889506 R 405955 CDS YP_859053.1 117625730 4494677 complement(3890480..3891589) 1 NC_008563.1 leucine transporter subunit 3891589 livK 4494677 livK Escherichia coli APEC O1 leucine transporter subunit YP_859053.1 3890480 R 405955 CDS YP_859054.1 117625731 4494678 3892013..3892396 1 NC_008563.1 hypothetical protein 3892396 yhhK 4494678 yhhK Escherichia coli APEC O1 hypothetical protein YP_859054.1 3892013 D 405955 CDS YP_859055.1 117625732 4494679 complement(3892584..3893744) 1 NC_008563.1 Leu/Ile/Val-binding protein precursor 3893744 livJ 4494679 livJ Escherichia coli APEC O1 Leu/Ile/Val-binding protein precursor YP_859055.1 3892584 R 405955 CDS YP_859056.1 117625733 4494680 3894691..3895023 1 NC_008563.1 PTS system component; hypothetical protein 3895023 4494680 APECO1_2998 Escherichia coli APEC O1 hypothetical protein YP_859056.1 3894691 D 405955 CDS YP_859057.1 117625734 4494681 3895030..3895515 1 NC_008563.1 PTS system component; hypothetical protein 3895515 4494681 APECO1_2997 Escherichia coli APEC O1 hypothetical protein YP_859057.1 3895030 D 405955 CDS YP_859058.1 117625735 4494682 3895532..3896278 1 NC_008563.1 hypothetical protein 3896278 4494682 APECO1_2996 Escherichia coli APEC O1 hypothetical protein YP_859058.1 3895532 D 405955 CDS YP_859059.1 117625736 4494683 3896223..3897125 1 NC_008563.1 phosphotransferase system enzyme II; hypothetical protein 3897125 4494683 APECO1_2995 Escherichia coli APEC O1 hypothetical protein YP_859059.1 3896223 D 405955 CDS YP_859060.1 117625737 4494684 3897417..3898055 1 NC_008563.1 similar to D-3-phosphoglycerate dehydrogenase; hypothetical protein 3898055 4494684 APECO1_2994 Escherichia coli APEC O1 hypothetical protein YP_859060.1 3897417 D 405955 CDS YP_859061.1 117625738 4494685 3898055..3898939 1 NC_008563.1 hypothetical protein 3898939 4494685 APECO1_2993 Escherichia coli APEC O1 hypothetical protein YP_859061.1 3898055 D 405955 CDS YP_859062.1 117625739 4494686 complement(3899043..3899897) 1 NC_008563.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3899897 rpoH 4494686 rpoH Escherichia coli APEC O1 RNA polymerase factor sigma-32 YP_859062.1 3899043 R 405955 CDS YP_859063.1 117625740 4494687 complement(3900142..3901227) 1 NC_008563.1 ABC transporter membrane protein; cell division protein FtsX 3901227 ftsX 4494687 ftsX Escherichia coli APEC O1 cell division protein FtsX YP_859063.1 3900142 R 405955 CDS YP_859064.1 117625741 4494688 complement(3901193..3901861) 1 NC_008563.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3901861 ftsE 4494688 ftsE Escherichia coli APEC O1 cell division protein FtsE YP_859064.1 3901193 R 405955 CDS YP_859065.1 117625742 4494689 complement(3901864..3903360) 1 NC_008563.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3903360 ftsY 4494689 ftsY Escherichia coli APEC O1 cell division protein FtsY YP_859065.1 3901864 R 405955 CDS YP_859066.1 117625743 4494690 3903510..3904106 1 NC_008563.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3904106 rsmD 4494690 rsmD Escherichia coli APEC O1 16S rRNA m(2)G966-methyltransferase YP_859066.1 3903510 D 405955 CDS YP_859067.1 117625744 4494691 complement(3904368..3904727) 1 NC_008563.1 hypothetical protein 3904727 yhhM 4494691 yhhM Escherichia coli APEC O1 hypothetical protein YP_859067.1 3904368 R 405955 CDS YP_859068.1 117625745 4494692 3904868..3905494 1 NC_008563.1 inner membrane protein; hypothetical protein 3905494 yhhN 4494692 yhhN Escherichia coli APEC O1 hypothetical protein YP_859068.1 3904868 D 405955 CDS YP_859069.1 117625746 4494693 3905568..3907766 1 NC_008563.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3907766 zntA 4494693 zntA Escherichia coli APEC O1 zinc/cadmium/mercury/lead-transporting ATPase YP_859069.1 3905568 D 405955 CDS YP_859071.1 117625748 4494695 3908501..3909166 1 NC_008563.1 hypothetical protein 3909166 yhhQ 4494695 yhhQ Escherichia coli APEC O1 hypothetical protein YP_859071.1 3908501 D 405955 CDS YP_859072.1 117625749 4494696 3909197..3909796 1 NC_008563.1 hypothetical protein 3909796 4494696 APECO1_2982 Escherichia coli APEC O1 hypothetical protein YP_859072.1 3909197 D 405955 CDS YP_859073.2 162317568 4495327 complement(3909800..3911017) 1 NC_008563.1 major facilitator superfamily transporter 3911017 yhhS 4495327 yhhS Escherichia coli APEC O1 major facilitator superfamily transporter YP_859073.2 3909800 R 405955 CDS YP_859074.1 117625751 4495328 3911149..3912198 1 NC_008563.1 hypothetical protein 3912198 yhhT 4495328 yhhT Escherichia coli APEC O1 hypothetical protein YP_859074.1 3911149 D 405955 CDS YP_859075.1 117625752 4495329 3912253..3912840 1 NC_008563.1 holo-(acyl carrier protein) synthase 2 3912840 acpT 4495329 acpT Escherichia coli APEC O1 holo-(acyl carrier protein) synthase 2 YP_859075.1 3912253 D 405955 CDS YP_859076.1 117625753 4495330 3912951..3914525 1 NC_008563.1 nickel-binding periplasmic protein NikA 3914525 nikA 4495330 nikA Escherichia coli APEC O1 nickel-binding periplasmic protein NikA YP_859076.1 3912951 D 405955 CDS YP_859077.1 117625754 4495331 3914525..3915469 1 NC_008563.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3915469 nikB 4495331 nikB Escherichia coli APEC O1 nickel transporter permease NikB YP_859077.1 3914525 D 405955 CDS YP_859078.1 117625755 4495332 3915466..3916299 1 NC_008563.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3916299 nikC 4495332 nikC Escherichia coli APEC O1 nickel transporter permease NikC YP_859078.1 3915466 D 405955 CDS YP_859079.1 117625756 4495333 3916299..3917063 1 NC_008563.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3917063 nikD 4495333 nikD Escherichia coli APEC O1 nickel transporter ATP-binding protein NikD YP_859079.1 3916299 D 405955 CDS YP_859080.1 117625757 4495334 3917060..3917866 1 NC_008563.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3917866 nikE 4495334 nikE Escherichia coli APEC O1 nickel transporter ATP-binding protein NikE YP_859080.1 3917060 D 405955 CDS YP_859081.1 117625758 4495335 3917872..3918273 1 NC_008563.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3918273 nikR 4495335 nikR Escherichia coli APEC O1 nickel responsive regulator YP_859081.1 3917872 D 405955 CDS YP_859082.1 117625759 4495336 3918463..3919218 1 NC_008563.1 regulatory protein 3919218 4495336 APECO1_2972 Escherichia coli APEC O1 regulatory protein YP_859082.1 3918463 D 405955 CDS YP_859083.1 117625760 4495337 3919243..3919716 1 NC_008563.1 phosphotransferase system enzyme subunit 3919716 4495337 APECO1_2971 Escherichia coli APEC O1 phosphotransferase system enzyme subunit YP_859083.1 3919243 D 405955 CDS YP_859084.1 117625761 4495338 3919713..3919994 1 NC_008563.1 phosphotransferase system enzyme subunit 3919994 4495338 APECO1_2970 Escherichia coli APEC O1 phosphotransferase system enzyme subunit YP_859084.1 3919713 D 405955 CDS YP_859085.1 117625762 4495339 3920041..3921429 1 NC_008563.1 PTS system galactitol-specific transporter subunit IIC 3921429 4495339 APECO1_2969 Escherichia coli APEC O1 PTS system galactitol-specific transporter subunit IIC YP_859085.1 3920041 D 405955 CDS YP_859086.1 117625763 4495340 3921422..3922930 1 NC_008563.1 xylulose kinase 3922930 4495340 APECO1_2968 Escherichia coli APEC O1 xylulose kinase YP_859086.1 3921422 D 405955 CDS YP_859087.1 117625764 4495341 3922920..3923189 1 NC_008563.1 phosphotransferase system HPr enzyme 3923189 4495341 APECO1_2967 Escherichia coli APEC O1 phosphotransferase system HPr enzyme YP_859087.1 3922920 D 405955 CDS YP_859088.1 117625765 4495342 3923221..3924072 1 NC_008563.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3924072 gatY 4495342 gatY Escherichia coli APEC O1 fructose-1,6-bisphosphate aldolase YP_859088.1 3923221 D 405955 CDS YP_859089.1 117625766 4495343 complement(3924182..3925306) 1 NC_008563.1 ABC transporter membrane protein 3925306 yhhJ 4495343 yhhJ Escherichia coli APEC O1 ABC transporter membrane protein YP_859089.1 3924182 R 405955 CDS YP_859090.1 117625767 4495344 complement(3925306..3928041) 1 NC_008563.1 fused ribosome-associated ATPase: ATP-binding protein, membrane protein 3928041 rbbA 4495344 rbbA Escherichia coli APEC O1 fused ribosome-associated ATPase: ATP-binding protein, membrane protein YP_859090.1 3925306 R 405955 CDS YP_859091.1 117625768 4495345 complement(3928038..3929105) 1 NC_008563.1 hypothetical protein 3929105 yhiI 4495345 yhiI Escherichia coli APEC O1 hypothetical protein YP_859091.1 3928038 R 405955 CDS YP_859092.1 117625769 4495115 3929827..3930891 1 NC_008563.1 hypothetical protein 3930891 yhiM 4495115 yhiM Escherichia coli APEC O1 hypothetical protein YP_859092.1 3929827 D 405955 CDS YP_859093.1 117625770 4495116 complement(3930978..3932171) 1 NC_008563.1 hypothetical protein 3932171 yhiN 4495116 yhiN Escherichia coli APEC O1 hypothetical protein YP_859093.1 3930978 R 405955 CDS YP_859094.1 117625771 4495117 3932403..3933902 1 NC_008563.1 phosphate transporter low-affinity 3933902 pitA 4495117 pitA Escherichia coli APEC O1 phosphate transporter low-affinity YP_859094.1 3932403 D 405955 CDS YP_859095.1 117625772 4495118 complement(3933973..3934308) 1 NC_008563.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3934308 uspB 4495118 uspB Escherichia coli APEC O1 universal stress protein UspB YP_859095.1 3933973 R 405955 CDS YP_859096.1 117625773 4495119 3934699..3935133 1 NC_008563.1 universal stress global response regulator UspA 3935133 uspA 4495119 uspA Escherichia coli APEC O1 universal stress global response regulator UspA YP_859096.1 3934699 D 405955 CDS YP_859097.1 117625774 4495120 3935450..3936919 1 NC_008563.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3936919 yhiP 4495120 yhiP Escherichia coli APEC O1 inner membrane transporter YhiP YP_859097.1 3935450 D 405955 CDS YP_859098.1 117625775 4495121 complement(3936968..3937825) 1 NC_008563.1 predicted SAM-dependent methyltransferase; methyltransferase 3937825 yhiQ 4495121 yhiQ Escherichia coli APEC O1 methyltransferase YP_859098.1 3936968 R 405955 CDS YP_859099.1 117625776 4495122 complement(3937728..3939770) 1 NC_008563.1 oligopeptidase A 3939770 prlC 4495122 prlC Escherichia coli APEC O1 oligopeptidase A YP_859099.1 3937728 R 405955 CDS YP_859100.1 117625777 4495123 3939973..3940815 1 NC_008563.1 DNA (exogenous) processing protein 3940815 yhiR 4495123 yhiR Escherichia coli APEC O1 DNA (exogenous) processing protein YP_859100.1 3939973 D 405955 CDS YP_859101.1 117625778 4495124 3940887..3942239 1 NC_008563.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3942239 gor 4495124 gor Escherichia coli APEC O1 glutathione reductase YP_859101.1 3940887 D 405955 CDS YP_859102.1 117625779 4495125 3942910..3943335 1 NC_008563.1 arsenate reductase 3943335 arsC 4495125 arsC Escherichia coli APEC O1 arsenate reductase YP_859102.1 3942910 D 405955 CDS YP_859103.1 117625780 4495126 3944486..3945085 1 NC_008563.1 outer membrane protein 3945085 slp 4495126 slp Escherichia coli APEC O1 outer membrane protein YP_859103.1 3944486 D 405955 CDS YP_859104.1 117625781 4495127 3945238..3945768 1 NC_008563.1 DNA-binding ranscriptional regulator 3945768 yhiF 4495127 yhiF Escherichia coli APEC O1 DNA-binding ranscriptional regulator YP_859104.1 3945238 D 405955 CDS YP_859105.1 117625782 4495128 complement(3945825..3946853) 1 NC_008563.1 heme/hemoglobin transport protein ChuS 3946853 chuS 4495128 chuS Escherichia coli APEC O1 heme/hemoglobin transport protein ChuS YP_859105.1 3945825 R 405955 CDS YP_859106.1 117625783 4495129 complement(3946902..3948884) 1 NC_008563.1 outer membrane heme/hemoglobin receptor ChuA 3948884 chuA 4495129 chuA Escherichia coli APEC O1 outer membrane heme/hemoglobin receptor ChuA YP_859106.1 3946902 R 405955 CDS YP_859107.1 117625784 4495130 3949568..3950482 1 NC_008563.1 periplasmic binding protein ChuT 3950482 chuT 4495130 chuT Escherichia coli APEC O1 periplasmic binding protein ChuT YP_859107.1 3949568 D 405955 CDS YP_859108.1 117625785 4495131 3950502..3951839 1 NC_008563.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3951839 chuW 4495131 chuW Escherichia coli APEC O1 coproporphyrinogen III oxidase YP_859108.1 3950502 D 405955 CDS YP_859109.1 117625786 4495132 3951852..3952346 1 NC_008563.1 hypothetical protein 3952346 4495132 APECO1_2945 Escherichia coli APEC O1 hypothetical protein YP_859109.1 3951852 D 405955 CDS YP_859110.1 117625787 4495133 3952346..3952969 1 NC_008563.1 hypothetical protein 3952969 4495133 APECO1_2944 Escherichia coli APEC O1 hypothetical protein YP_859110.1 3952346 D 405955 CDS YP_859111.1 117625788 4495134 3953054..3954010 1 NC_008563.1 permease of iron ABCtransport system 3954010 chuU 4495134 chuU Escherichia coli APEC O1 permease of iron ABCtransport system YP_859111.1 3953054 D 405955 CDS YP_859112.1 117625789 4495484 3954007..3954777 1 NC_008563.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3954777 hmuV 4495484 hmuV Escherichia coli APEC O1 hemin importer ATP-binding subunit YP_859112.1 3954007 D 405955 CDS YP_859113.1 117625790 4495485 complement(3954829..3955476) 1 NC_008563.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 3955476 yhiD 4495485 yhiD Escherichia coli APEC O1 Mg(2+) transport ATPase YP_859113.1 3954829 R 405955 CDS YP_859114.1 117625791 4495486 complement(3955540..3955878) 1 NC_008563.1 acid-resistance protein 3955878 hdeB 4495486 hdeB Escherichia coli APEC O1 acid-resistance protein YP_859114.1 3955540 R 405955 CDS YP_859115.1 117625792 4495487 complement(3955982..3956314) 1 NC_008563.1 inactive form; acid-resistance protein 3956314 hdeA 4495487 hdeA Escherichia coli APEC O1 acid-resistance protein YP_859115.1 3955982 R 405955 CDS YP_859116.1 117625793 4495488 3956569..3957141 1 NC_008563.1 acid-resistance membrane protein 3957141 hdeD 4495488 hdeD Escherichia coli APEC O1 acid-resistance membrane protein YP_859116.1 3956569 D 405955 CDS YP_859117.1 117625794 4495489 3957907..3958467 1 NC_008563.1 DNA-binding transcriptional activator 3958467 gadE 4495489 gadE Escherichia coli APEC O1 DNA-binding transcriptional activator YP_859117.1 3957907 D 405955 CDS YP_859118.1 117625795 4495490 3958511..3958804 1 NC_008563.1 hypothetical protein 3958804 4495490 APECO1_2936 Escherichia coli APEC O1 hypothetical protein YP_859118.1 3958511 D 405955 CDS YP_859119.1 117625796 4495491 3958806..3959963 1 NC_008563.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3959963 mdtE 4495491 mdtE Escherichia coli APEC O1 multidrug efflux system protein MdtE YP_859119.1 3958806 D 405955 CDS YP_859120.1 117625797 4495492 3959988..3963101 1 NC_008563.1 multidrug transporter MdtF, RpoS-dependent 3963101 mdtF 4495492 mdtF Escherichia coli APEC O1 multidrug transporter MdtF, RpoS-dependent YP_859120.1 3959988 D 405955 CDS YP_859121.1 117625798 4495493 complement(3963464..3964192) 1 NC_008563.1 DNA-binding transcriptional activator YhiW 3964192 yhiW 4495493 yhiW Escherichia coli APEC O1 DNA-binding transcriptional activator YhiW YP_859121.1 3963464 R 405955 CDS YP_859122.1 117625799 4495494 complement(3964560..3965384) 1 NC_008563.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3965384 gadX 4495494 gadX Escherichia coli APEC O1 DNA-binding transcriptional regulator GadX YP_859122.1 3964560 R 405955 CDS YP_859123.1 117625800 4495495 complement(3965752..3967182) 1 NC_008563.1 glutamate decarboxylase 3967182 gadB 4495495 gadB Escherichia coli APEC O1 glutamate decarboxylase YP_859123.1 3965752 R 405955 CDS YP_859124.1 117625801 4495496 complement(3967363..3968760) 1 NC_008563.1 cytochrome C peroxidase 3968760 yhjA 4495496 yhjA Escherichia coli APEC O1 cytochrome C peroxidase YP_859124.1 3967363 R 405955 CDS YP_859125.1 117625802 4495497 3969165..3970814 1 NC_008563.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3970814 treF 4495497 treF Escherichia coli APEC O1 trehalase YP_859125.1 3969165 D 405955 CDS YP_859126.1 117625803 4495498 complement(3970865..3971467) 1 NC_008563.1 DNA-binding response regulator in two-component regulatory system 3971467 yhjB 4495498 yhjB Escherichia coli APEC O1 DNA-binding response regulator in two-component regulatory system YP_859126.1 3970865 R 405955 CDS YP_859127.1 117625804 4495499 3971915..3972886 1 NC_008563.1 DNA-binding transcriptional regulator YhjC 3972886 yhjC 4495499 yhjC Escherichia coli APEC O1 DNA-binding transcriptional regulator YhjC YP_859127.1 3971915 D 405955 CDS YP_859128.1 117625805 4495500 3972935..3973948 1 NC_008563.1 hypothetical protein 3973948 yhjD 4495500 yhjD Escherichia coli APEC O1 hypothetical protein YP_859128.1 3972935 D 405955 CDS YP_859129.1 117625806 4495501 3974341..3975663 1 NC_008563.1 metabolite transport protein YhjE 3975663 yhjE 4495501 yhjE Escherichia coli APEC O1 metabolite transport protein YhjE YP_859129.1 3974341 D 405955 CDS YP_859130.1 117625807 4495502 complement(3975704..3977779) 1 NC_008563.1 outer membrane biogenesis protein YhjG 3977779 yhjG 4495502 yhjG Escherichia coli APEC O1 outer membrane biogenesis protein YhjG YP_859130.1 3975704 R 405955 CDS YP_859131.1 117625808 4494081 complement(3977834..3978601) 1 NC_008563.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 3978601 yhjJ 4494081 yhjJ Escherichia coli APEC O1 EAL domain-containing protein YP_859131.1 3977834 R 405955 CDS YP_859132.1 117625809 4494082 3978614..3979762 1 NC_008563.1 2-dehydro-3-deoxygluconokinase 3979762 kdgK 4494082 kdgK Escherichia coli APEC O1 2-dehydro-3-deoxygluconokinase YP_859132.1 3978614 D 405955 CDS YP_859133.1 117625810 4494083 complement(3979858..3981354) 1 NC_008563.1 zinc-dependent peptidase 3981354 yhjJ 4494083 yhjJ Escherichia coli APEC O1 zinc-dependent peptidase YP_859133.1 3979858 R 405955 CDS YP_859134.1 117625811 4494084 complement(3981574..3982860) 1 NC_008563.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 3982860 dctA 4494084 dctA Escherichia coli APEC O1 C4-dicarboxylate transporter DctA YP_859134.1 3981574 R 405955 CDS YP_859135.1 117625812 4494085 complement(3983043..3984998) 1 NC_008563.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase 3984998 yhjK 4494085 yhjK Escherichia coli APEC O1 phosphodiesterase YP_859135.1 3983043 R 405955 CDS YP_859136.1 117625813 4494086 complement(3985113..3988586) 1 NC_008563.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 3988586 yhjL 4494086 yhjL Escherichia coli APEC O1 cellulose synthase subunit BcsC YP_859136.1 3985113 R 405955 CDS YP_859137.1 117625814 4494087 complement(3988568..3989674) 1 NC_008563.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 3989674 bcsZ 4494087 bcsZ Escherichia coli APEC O1 endo-1,4-D-glucanase YP_859137.1 3988568 R 405955 CDS YP_859138.1 117625815 4494088 complement(3989681..3992020) 1 NC_008563.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 3992020 bcsB 4494088 bcsB Escherichia coli APEC O1 cellulose synthase regulator protein YP_859138.1 3989681 R 405955 CDS YP_859139.1 117625816 4494089 complement(3992031..3994697) 1 NC_008563.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 3994697 bcsA 4494089 bcsA Escherichia coli APEC O1 cellulose synthase catalytic subunit YP_859139.1 3992031 R 405955 CDS YP_859140.1 117625817 4494090 complement(3994646..3995398) 1 NC_008563.1 cell division protein 3995398 yhjQ 4494090 yhjQ Escherichia coli APEC O1 cell division protein YP_859140.1 3994646 R 405955 CDS YP_859141.1 117625818 4494091 3995871..3997442 1 NC_008563.1 hypothetical protein 3997442 yhjS 4494091 yhjS Escherichia coli APEC O1 hypothetical protein YP_859141.1 3995871 D 405955 CDS YP_859142.1 117625819 4494092 3997627..3999306 1 NC_008563.1 inner membrane protein; hypothetical protein 3999306 yhjU 4494092 yhjU Escherichia coli APEC O1 hypothetical protein YP_859142.1 3997627 D 405955 CDS YP_859143.1 117625820 4494094 3999571..3999870 1 NC_008563.1 hypothetical protein 3999870 4494094 APECO1_2912 Escherichia coli APEC O1 hypothetical protein YP_859143.1 3999571 D 405955 CDS YP_859144.1 117625821 4494095 4000045..4000341 1 NC_008563.1 hypothetical protein 4000341 4494095 APECO1_2911 Escherichia coli APEC O1 hypothetical protein YP_859144.1 4000045 D 405955 CDS YP_859145.1 117625822 4494096 complement(4000357..4000632) 1 NC_008563.1 hypothetical protein 4000632 4494096 APECO1_2910 Escherichia coli APEC O1 hypothetical protein YP_859145.1 4000357 R 405955 CDS YP_859146.1 117625823 4494097 4000940..4002211 1 NC_008563.1 hypothetical protein 4002211 yhjV 4494097 yhjV Escherichia coli APEC O1 hypothetical protein YP_859146.1 4000940 D 405955 CDS YP_859147.1 117625824 4494098 complement(4002241..4003245) 1 NC_008563.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4003245 dppF 4494098 dppF Escherichia coli APEC O1 dipeptide transporter ATP-binding subunit YP_859147.1 4002241 R 405955 CDS YP_859148.1 117625825 4494099 complement(4003242..4004225) 1 NC_008563.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4004225 dppD 4494099 dppD Escherichia coli APEC O1 dipeptide transporter ATP-binding subunit YP_859148.1 4003242 R 405955 CDS YP_859149.1 117625826 4494100 complement(4004236..4005138) 1 NC_008563.1 dipeptide transporter 4005138 dppC 4494100 dppC Escherichia coli APEC O1 dipeptide transporter YP_859149.1 4004236 R 405955 CDS YP_859150.1 117625827 4492757 complement(4005148..4006167) 1 NC_008563.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4006167 dppB 4492757 dppB Escherichia coli APEC O1 dipeptide transporter permease DppB YP_859150.1 4005148 R 405955 CDS YP_859151.1 117625828 4492758 complement(4006318..4007925) 1 NC_008563.1 dipeptide transporter protein DppA 4007925 dppA 4492758 dppA Escherichia coli APEC O1 dipeptide transporter protein DppA YP_859151.1 4006318 R 405955 CDS YP_859153.1 117625830 4492760 complement(4008834..4010525) 1 NC_008563.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4010525 yhjW 4492760 yhjW Escherichia coli APEC O1 phosphoethanolamine transferase YP_859153.1 4008834 R 405955 CDS YP_859154.1 117625831 4492761 complement(4010849..4012057) 1 NC_008563.1 permease; transporter 4012057 yhjX 4492761 yhjX Escherichia coli APEC O1 transporter YP_859154.1 4010849 R 405955 CDS YP_859155.1 117625832 4492762 complement(4012286..4012984) 1 NC_008563.1 hypothetical protein 4012984 yhjY 4492762 yhjY Escherichia coli APEC O1 hypothetical protein YP_859155.1 4012286 R 405955 CDS YP_859156.2 162317567 4492763 4013142..4013705 1 NC_008563.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 4013705 tag 4492763 tag Escherichia coli APEC O1 3-methyladenine DNA glycosylase YP_859156.2 4013142 D 405955 CDS YP_859157.1 117625834 4492764 4013702..4014142 1 NC_008563.1 hypothetical protein 4014142 yiaC 4492764 yiaC Escherichia coli APEC O1 hypothetical protein YP_859157.1 4013702 D 405955 CDS YP_859158.1 117625835 4492765 complement(4014111..4016390) 1 NC_008563.1 biotin sulfoxide reductase 4016390 bisC 4492765 bisC Escherichia coli APEC O1 biotin sulfoxide reductase YP_859158.1 4014111 R 405955 CDS YP_859159.1 117625836 4492766 4016597..4017256 1 NC_008563.1 lipoprotein; outer membrane lipoprotein 4017256 yiaD 4492766 yiaD Escherichia coli APEC O1 outer membrane lipoprotein YP_859159.1 4016597 D 405955 CDS YP_859160.1 117625837 4492767 4017348..4018334 1 NC_008563.1 2-ketoaldonate reductase/glyoxylate reductase B 4018334 tkrA 4492767 tkrA Escherichia coli APEC O1 2-ketoaldonate reductase/glyoxylate reductase B YP_859160.1 4017348 D 405955 CDS YP_859161.1 117625838 4492768 complement(4018384..4019214) 1 NC_008563.1 hypothetical protein 4019214 yiaF 4492768 yiaF Escherichia coli APEC O1 hypothetical protein YP_859161.1 4018384 R 405955 CDS YP_859162.1 117625839 4492769 4019528..4019818 1 NC_008563.1 transcriptional regulator 4019818 yiaG 4492769 yiaG Escherichia coli APEC O1 transcriptional regulator YP_859162.1 4019528 D 405955 CDS YP_859163.1 117625840 4492770 complement(4020036..4020461) 1 NC_008563.1 hypothetical protein 4020461 4492770 APECO1_2892 Escherichia coli APEC O1 hypothetical protein YP_859163.1 4020036 R 405955 CDS YP_859164.1 117625841 4492771 complement(4020974..4023043) 1 NC_008563.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4023043 glyS 4492771 glyS Escherichia coli APEC O1 glycyl-tRNA synthetase subunit beta YP_859164.1 4020974 R 405955 CDS YP_859165.1 117625842 4492772 complement(4023053..4023964) 1 NC_008563.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4023964 glyQ 4492772 glyQ Escherichia coli APEC O1 glycyl-tRNA synthetase subunit alpha YP_859165.1 4023053 R 405955 CDS YP_859166.1 117625843 4492773 complement(4024059..4024358) 1 NC_008563.1 lipoprotein; hypothetical protein 4024358 ysaB 4492773 ysaB Escherichia coli APEC O1 hypothetical protein YP_859166.1 4024059 R 405955 CDS YP_859167.1 117625844 4492774 4024533..4025528 1 NC_008563.1 hypothetical protein 4025528 yiaH 4492774 yiaH Escherichia coli APEC O1 hypothetical protein YP_859167.1 4024533 D 405955 CDS YP_859168.1 117625845 4492775 complement(4025570..4026007) 1 NC_008563.1 hypothetical protein 4026007 yiaA 4492775 yiaA Escherichia coli APEC O1 hypothetical protein YP_859168.1 4025570 R 405955 CDS YP_859169.1 117625846 4492678 complement(4026053..4026406) 1 NC_008563.1 inner membrane protein; hypothetical protein 4026406 yiaB 4492678 yiaB Escherichia coli APEC O1 hypothetical protein YP_859169.1 4026053 R 405955 CDS YP_859170.1 117625847 4492679 complement(4026563..4028017) 1 NC_008563.1 xylulokinase 4028017 xylB 4492679 xylB Escherichia coli APEC O1 xylulokinase YP_859170.1 4026563 R 405955 CDS YP_859171.2 162317566 4492680 complement(4028089..4029411) 1 NC_008563.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4029411 xylA 4492680 xylA Escherichia coli APEC O1 xylose isomerase YP_859171.2 4028089 R 405955 CDS YP_859172.1 117625849 4492681 4029777..4030769 1 NC_008563.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4030769 xylF 4492681 xylF Escherichia coli APEC O1 D-xylose transporter subunit XylF YP_859172.1 4029777 D 405955 CDS YP_859173.2 229775954 4492682 4030847..4032388 1 NC_008563.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4032388 xylG 4492682 xylG Escherichia coli APEC O1 xylose transporter ATP-binding subunit YP_859173.2 4030847 D 405955 CDS YP_859174.1 117625851 4492683 4032366..4033547 1 NC_008563.1 DNA-binding transcriptional activator, xylose-binding 4033547 xylH 4492683 xylH Escherichia coli APEC O1 DNA-binding transcriptional activator, xylose-binding YP_859174.1 4032366 D 405955 CDS YP_859175.1 117625852 4492684 4033625..4034803 1 NC_008563.1 DNA-binding transcriptional activator, xylose-binding 4034803 xylR 4492684 xylR Escherichia coli APEC O1 DNA-binding transcriptional activator, xylose-binding YP_859175.1 4033625 D 405955 CDS YP_859176.1 117625853 4492685 complement(4034911..4035735) 1 NC_008563.1 hypothetical protein 4035735 bax 4492685 bax Escherichia coli APEC O1 hypothetical protein YP_859176.1 4034911 R 405955 CDS YP_859177.1 117625854 4492686 4036055..4038085 1 NC_008563.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4038085 malS 4492686 malS Escherichia coli APEC O1 periplasmic alpha-amylase YP_859177.1 4036055 D 405955 CDS YP_859178.1 117625855 4492687 4038263..4039516 1 NC_008563.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4039516 avtA 4492687 avtA Escherichia coli APEC O1 valine--pyruvate transaminase YP_859178.1 4038263 D 405955 CDS YP_859179.1 117625856 4492688 complement(4039668..4040147) 1 NC_008563.1 electron transport protein YsaA 4040147 ysaA 4492688 ysaA Escherichia coli APEC O1 electron transport protein YsaA YP_859179.1 4039668 R 405955 CDS YP_859180.1 117625857 4492689 complement(4040243..4041091) 1 NC_008563.1 DNA-binding transcriptional repressor 4041091 yiaJ 4492689 yiaJ Escherichia coli APEC O1 DNA-binding transcriptional repressor YP_859180.1 4040243 R 405955 CDS YP_859181.1 117625858 4492690 4041292..4042290 1 NC_008563.1 oxidoreductase; NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4042290 yiaK 4492690 yiaK Escherichia coli APEC O1 2,3-diketo-L-gulonate reductase YP_859181.1 4041292 D 405955 CDS YP_859182.1 117625859 4492691 4042302..4042766 1 NC_008563.1 hypothetical protein 4042766 yiaL 4492691 yiaL Escherichia coli APEC O1 hypothetical protein YP_859182.1 4042302 D 405955 CDS YP_859183.1 117625860 4492692 4042789..4043709 1 NC_008563.1 hypothetical protein 4043709 4492692 APECO1_2873 Escherichia coli APEC O1 hypothetical protein YP_859183.1 4042789 D 405955 CDS YP_859184.1 117625861 4492693 4044095..4045567 1 NC_008563.1 YiaN-like; DedA family membrane protein 4045567 4492693 APECO1_2872 Escherichia coli APEC O1 DedA family membrane protein YP_859184.1 4044095 D 405955 CDS YP_859185.1 117625862 4492694 4045585..4046571 1 NC_008563.1 extracellular substrate-binding protein YiaO 4046571 yiaO 4492694 yiaO Escherichia coli APEC O1 extracellular substrate-binding protein YiaO YP_859185.1 4045585 D 405955 CDS YP_859186.1 117625863 4492695 4046575..4048071 1 NC_008563.1 L-xylulose kinase 4048071 lyxK 4492695 lyxK Escherichia coli APEC O1 L-xylulose kinase YP_859186.1 4046575 D 405955 CDS YP_859187.1 117625864 4492696 4048068..4048730 1 NC_008563.1 3-hexulose-6-phosphate synthase; catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4048730 sgbH 4492696 sgbH Escherichia coli APEC O1 3-keto-L-gulonate-6-phosphate decarboxylase YP_859187.1 4048068 D 405955 CDS YP_859188.1 117625865 4492697 4048690..4049583 1 NC_008563.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4049583 sgbU 4492697 sgbU Escherichia coli APEC O1 L-xylulose 5-phosphate 3-epimerase YP_859188.1 4048690 D 405955 CDS YP_859189.1 117625866 4491772 complement(4049580..4050317) 1 NC_008563.1 hypothetical protein 4050317 4491772 APECO1_2867 Escherichia coli APEC O1 hypothetical protein YP_859189.1 4049580 R 405955 CDS YP_859190.1 117625867 4491774 complement(4050319..4051947) 1 NC_008563.1 lactaldehyde dehydrogenase 4051947 aldB 4491774 aldB Escherichia coli APEC O1 lactaldehyde dehydrogenase YP_859190.1 4050319 R 405955 CDS YP_859191.1 117625868 4491775 complement(4051965..4053260) 1 NC_008563.1 hypothetical protein 4053260 4491775 APECO1_2865 Escherichia coli APEC O1 hypothetical protein YP_859191.1 4051965 R 405955 CDS YP_859192.1 117625869 4491776 complement(4053390..4054541) 1 NC_008563.1 alcohol dehydrogenase 4054541 yiaY 4491776 yiaY Escherichia coli APEC O1 alcohol dehydrogenase YP_859192.1 4053390 R 405955 CDS YP_859193.1 117625870 4491777 complement(4054732..4056576) 1 NC_008563.1 selenocysteinyl-tRNA-specific translation factor 4056576 selB 4491777 selB Escherichia coli APEC O1 selenocysteinyl-tRNA-specific translation factor YP_859193.1 4054732 R 405955 CDS YP_859194.1 117625871 4491778 complement(4056573..4057964) 1 NC_008563.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4057964 selA 4491778 selA Escherichia coli APEC O1 selenocysteine synthase YP_859194.1 4056573 R 405955 CDS YP_859195.1 117625872 4491779 complement(4058062..4058670) 1 NC_008563.1 glutathione S-transferase 4058670 yibF 4491779 yibF Escherichia coli APEC O1 glutathione S-transferase YP_859195.1 4058062 R 405955 CDS YP_859196.1 117625873 4491780 complement(4058741..4059877) 1 NC_008563.1 hypothetical protein 4059877 yibH 4491780 yibH Escherichia coli APEC O1 hypothetical protein YP_859196.1 4058741 R 405955 CDS YP_859197.1 117625874 4491781 complement(4059880..4060242) 1 NC_008563.1 inner membrane protein; hypothetical protein 4060242 yibI 4491781 yibI Escherichia coli APEC O1 hypothetical protein YP_859197.1 4059880 R 405955 CDS YP_859198.1 117625875 4491782 4060778..4062691 1 NC_008563.1 PTS system mannitol-specific transporter subunit IIABC 4062691 mtlA 4491782 mtlA Escherichia coli APEC O1 PTS system mannitol-specific transporter subunit IIABC YP_859198.1 4060778 D 405955 CDS YP_859199.1 117625876 4491783 4062830..4064158 1 NC_008563.1 mannitol-1-phosphate 5-dehydrogenase 4064158 mtlD 4491783 mtlD Escherichia coli APEC O1 mannitol-1-phosphate 5-dehydrogenase YP_859199.1 4062830 D 405955 CDS YP_859200.1 117625877 4491784 4064158..4064745 1 NC_008563.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4064745 mtlR 4491784 mtlR Escherichia coli APEC O1 mannitol repressor protein YP_859200.1 4064158 D 405955 CDS YP_859201.1 117625878 4491785 4065249..4065611 1 NC_008563.1 hypothetical protein 4065611 4491785 APECO1_2855 Escherichia coli APEC O1 hypothetical protein YP_859201.1 4065249 D 405955 CDS YP_859202.1 117625879 4491786 4066404..4066853 1 NC_008563.1 hypothetical protein 4066853 4491786 APECO1_2854 Escherichia coli APEC O1 hypothetical protein YP_859202.1 4066404 D 405955 CDS YP_859203.1 117625880 4491787 4066897..4071648 1 NC_008563.1 autotransporter/adhesin 4071648 yadA 4491787 yadA Escherichia coli APEC O1 autotransporter/adhesin YP_859203.1 4066897 D 405955 CDS YP_859204.1 117625881 4491788 4072058..4073713 1 NC_008563.1 L-lactate permease 4073713 lldP 4491788 lldP Escherichia coli APEC O1 L-lactate permease YP_859204.1 4072058 D 405955 CDS YP_859205.1 117625882 4491789 4073713..4074489 1 NC_008563.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4074489 lldR 4491789 lldR Escherichia coli APEC O1 DNA-binding transcriptional repressor LldR YP_859205.1 4073713 D 405955 CDS YP_859206.1 117625883 4491790 4074486..4075676 1 NC_008563.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4075676 lldD 4491790 lldD Escherichia coli APEC O1 L-lactate dehydrogenase YP_859206.1 4074486 D 405955 CDS YP_859207.1 117625884 4493516 4075724..4076197 1 NC_008563.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4076197 yibK 4493516 yibK Escherichia coli APEC O1 tRNA/rRNA methyltransferase YibK YP_859207.1 4075724 D 405955 CDS YP_859208.1 117625885 4493517 complement(4076252..4077073) 1 NC_008563.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4077073 cysE 4493517 cysE Escherichia coli APEC O1 serine acetyltransferase YP_859208.1 4076252 R 405955 CDS YP_859209.1 117625886 4493518 complement(4077153..4078172) 1 NC_008563.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4078172 gpsA 4493518 gpsA Escherichia coli APEC O1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_859209.1 4077153 R 405955 CDS YP_859210.1 117625887 4493519 complement(4078172..4078699) 1 NC_008563.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4078699 secB 4493519 secB Escherichia coli APEC O1 preprotein translocase subunit SecB YP_859210.1 4078172 R 405955 CDS YP_859211.1 117625888 4493520 4078769..4079038 1 NC_008563.1 hypothetical protein 4079038 4493520 APECO1_2845 Escherichia coli APEC O1 hypothetical protein YP_859211.1 4078769 D 405955 CDS YP_859212.1 117625889 4493521 complement(4079095..4079526) 1 NC_008563.1 rhodanese-related sulfurtransferase 4079526 yibN 4493521 yibN Escherichia coli APEC O1 rhodanese-related sulfurtransferase YP_859212.1 4079095 R 405955 CDS YP_859213.1 117625890 4493522 4079771..4081315 1 NC_008563.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4081315 yibO 4493522 yibO Escherichia coli APEC O1 phosphoglyceromutase YP_859213.1 4079771 D 405955 CDS YP_859214.1 117625891 4493523 4081325..4082608 1 NC_008563.1 hypothetical protein 4082608 envC 4493523 envC Escherichia coli APEC O1 hypothetical protein YP_859214.1 4081325 D 405955 CDS YP_859215.1 117625892 4493524 4082738..4083571 1 NC_008563.1 polysaccharide deacetylase 4083571 yibQ 4493524 yibQ Escherichia coli APEC O1 polysaccharide deacetylase YP_859215.1 4082738 D 405955 CDS YP_859216.1 117625893 4493525 complement(4083558..4084592) 1 NC_008563.1 glycosyl transferase family protein 4084592 yibD 4493525 yibD Escherichia coli APEC O1 glycosyl transferase family protein YP_859216.1 4083558 R 405955 CDS YP_859217.1 117625894 4493526 complement(4084831..4085856) 1 NC_008563.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4085856 tdh 4493526 tdh Escherichia coli APEC O1 L-threonine 3-dehydrogenase YP_859217.1 4084831 R 405955 CDS YP_859218.1 117625895 4492582 complement(4085866..4087062) 1 NC_008563.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 4087062 kbl 4492582 kbl Escherichia coli APEC O1 2-amino-3-ketobutyrate coenzyme A ligase YP_859218.1 4085866 R 405955 CDS YP_859219.1 117625896 4492583 4087276..4088208 1 NC_008563.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4088208 rfaD 4492583 rfaD Escherichia coli APEC O1 ADP-L-glycero-D-manno-heptose-6-epimerase YP_859219.1 4087276 D 405955 CDS YP_859220.1 117625897 4492584 4088218..4089264 1 NC_008563.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4089264 rfaF 4492584 rfaF Escherichia coli APEC O1 ADP-heptose--LPS heptosyltransferase YP_859220.1 4088218 D 405955 CDS YP_859221.1 117625898 4492585 4089268..4090248 1 NC_008563.1 ADP-heptose--LPS heptosyltransferase 4090248 rfaC 4492585 rfaC Escherichia coli APEC O1 ADP-heptose--LPS heptosyltransferase YP_859221.1 4089268 D 405955 CDS YP_859222.1 117625899 4492586 complement(4090318..4091571) 1 NC_008563.1 lipid A-core, surface polymer ligase 4091571 waaL 4492586 waaL Escherichia coli APEC O1 lipid A-core, surface polymer ligase YP_859222.1 4090318 R 405955 CDS YP_859223.1 117625900 4492587 complement(4091617..4092600) 1 NC_008563.1 beta-1,3-glucosyltransferase 4092600 waaV 4492587 waaV Escherichia coli APEC O1 beta-1,3-glucosyltransferase YP_859223.1 4091617 R 405955 CDS YP_859224.1 117625901 4492588 complement(4092682..4093710) 1 NC_008563.1 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase 4093710 rfaJ 4492588 rfaJ Escherichia coli APEC O1 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase YP_859224.1 4092682 R 405955 CDS YP_859225.1 117625902 4492589 complement(4093736..4094428) 1 NC_008563.1 lipopolysaccharide core biosynthesis protein 4094428 4492589 APECO1_2831 Escherichia coli APEC O1 lipopolysaccharide core biosynthesis protein YP_859225.1 4093736 R 405955 CDS YP_859226.1 117625903 4492590 complement(4094438..4095433) 1 NC_008563.1 lipopolysaccharide 1,2-glucosyltransferase 4095433 rfaJ 4492590 rfaJ Escherichia coli APEC O1 lipopolysaccharide 1,2-glucosyltransferase YP_859226.1 4094438 R 405955 CDS YP_859227.1 117625904 4492591 complement(4095450..4096466) 1 NC_008563.1 lipopolysaccharide 1,3-galactosyltransferase 4096466 rafI 4492591 rafI Escherichia coli APEC O1 lipopolysaccharide 1,3-galactosyltransferase YP_859227.1 4095450 R 405955 CDS YP_859228.1 117625905 4492592 complement(4096482..4097288) 1 NC_008563.1 lipopolysaccharide core biosynthesis protein RfaP 4097288 rfaP 4492592 rfaP Escherichia coli APEC O1 lipopolysaccharide core biosynthesis protein RfaP YP_859228.1 4096482 R 405955 CDS YP_859229.1 117625906 4492593 complement(4097272..4098396) 1 NC_008563.1 lipopolysaccharide core biosynthesis glucosyltransferase I 4098396 rfaG 4492593 rfaG Escherichia coli APEC O1 lipopolysaccharide core biosynthesis glucosyltransferase I YP_859229.1 4097272 R 405955 CDS YP_859230.1 117625907 4492594 complement(4098393..4099451) 1 NC_008563.1 lipopolysaccharide core biosynthesis protein 4099451 rfaQ 4492594 rfaQ Escherichia coli APEC O1 lipopolysaccharide core biosynthesis protein YP_859230.1 4098393 R 405955 CDS YP_859231.1 117625908 4492595 4099864..4101141 1 NC_008563.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4101141 kdtA 4492595 kdtA Escherichia coli APEC O1 3-deoxy-D-manno-octulosonic-acid transferase YP_859231.1 4099864 D 405955 CDS YP_859232.1 117625909 4492596 complement(4101667..4102476) 1 NC_008563.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4102476 mutM 4492596 mutM Escherichia coli APEC O1 formamidopyrimidine-DNA glycosylase YP_859232.1 4101667 R 405955 CDS YP_859233.1 117625910 4492597 complement(4103215..4103889) 1 NC_008563.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4103889 radC 4492597 radC Escherichia coli APEC O1 DNA repair protein RadC YP_859233.1 4103215 R 405955 CDS YP_859234.2 229775953 4492598 4104055..4105275 1 NC_008563.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4105275 dfp 4492598 dfp Escherichia coli APEC O1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_859234.2 4104055 D 405955 CDS YP_859235.1 117625912 4492599 4105253..4105711 1 NC_008563.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4105711 dut 4492599 dut Escherichia coli APEC O1 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_859235.1 4105253 D 405955 CDS YP_859236.1 117625913 4492600 4105776..4106414 1 NC_008563.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4106414 slmA 4492600 slmA Escherichia coli APEC O1 nucleoid occlusion protein YP_859236.1 4105776 D 405955 CDS YP_859237.1 117625914 4495269 complement(4106451..4107107) 1 NC_008563.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4107107 pyrE 4495269 pyrE Escherichia coli APEC O1 orotate phosphoribosyltransferase YP_859237.1 4106451 R 405955 CDS YP_859238.1 117625915 4495270 complement(4107158..4107874) 1 NC_008563.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4107874 rph 4495270 rph Escherichia coli APEC O1 ribonuclease PH YP_859238.1 4107158 R 405955 CDS YP_859239.1 117625916 4495271 4108001..4108864 1 NC_008563.1 alpha-helix protein; hypothetical protein 4108864 yicC 4495271 yicC Escherichia coli APEC O1 hypothetical protein YP_859239.1 4108001 D 405955 CDS YP_859240.1 117625917 4495272 4109074..4109910 1 NC_008563.1 DNA-damage-inducible protein D 4109910 dinD 4495272 dinD Escherichia coli APEC O1 DNA-damage-inducible protein D YP_859240.1 4109074 D 405955 CDS YP_859241.1 117625918 4495273 4110148..4110819 1 NC_008563.1 hypothetical protein 4110819 4495273 APECO1_2815 Escherichia coli APEC O1 hypothetical protein YP_859241.1 4110148 D 405955 CDS YP_859242.1 117625919 4495274 complement(4110816..4112504) 1 NC_008563.1 LigB; this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4112504 ligB 4495274 ligB Escherichia coli APEC O1 NAD-dependent DNA ligase LigB YP_859242.1 4110816 R 405955 CDS YP_859243.1 117625920 4495275 4112699..4113379 1 NC_008563.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4113379 gmk 4495275 gmk Escherichia coli APEC O1 guanylate kinase YP_859243.1 4112699 D 405955 CDS YP_859244.1 117625921 4495276 4113434..4113709 1 NC_008563.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4113709 rpoZ 4495276 rpoZ Escherichia coli APEC O1 DNA-directed RNA polymerase subunit omega YP_859244.1 4113434 D 405955 CDS YP_859245.1 117625922 4495277 4113875..4115836 1 NC_008563.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4115836 spoT 4495277 spoT Escherichia coli APEC O1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_859245.1 4113875 D 405955 CDS YP_859246.1 117625923 4495278 4115843..4116532 1 NC_008563.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4116532 spoU 4495278 spoU Escherichia coli APEC O1 tRNA guanosine-2'-O-methyltransferase YP_859246.1 4115843 D 405955 CDS YP_859247.1 117625924 4495279 4116505..4118619 1 NC_008563.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4118619 recG 4495279 recG Escherichia coli APEC O1 ATP-dependent DNA helicase RecG YP_859247.1 4116505 D 405955 CDS YP_859248.1 117625925 4495280 complement(4118653..4119858) 1 NC_008563.1 glutamate transport protein 4119858 4495280 APECO1_2808 Escherichia coli APEC O1 glutamate transport protein YP_859248.1 4118653 R 405955 CDS YP_859249.1 117625926 4495281 4120138..4121529 1 NC_008563.1 purine permease YicE 4121529 yicE 4495281 yicE Escherichia coli APEC O1 purine permease YicE YP_859249.1 4120138 D 405955 CDS YP_859250.1 117625927 4495282 4121626..4123359 1 NC_008563.1 hypothetical protein 4123359 yicH 4495282 yicH Escherichia coli APEC O1 hypothetical protein YP_859250.1 4121626 D 405955 CDS YP_859251.1 117625928 4495283 complement(4123403..4124122) 1 NC_008563.1 hypothetical protein 4124122 4495283 APECO1_2805 Escherichia coli APEC O1 hypothetical protein YP_859251.1 4123403 R 405955 CDS YP_859252.1 117625929 4495284 complement(4124064..4125029) 1 NC_008563.1 hypothetical protein 4125029 yajF 4495284 yajF Escherichia coli APEC O1 hypothetical protein YP_859252.1 4124064 R 405955 CDS YP_859253.1 117625930 4495285 complement(4125044..4125904) 1 NC_008563.1 hypothetical protein 4125904 4495285 APECO1_2803 Escherichia coli APEC O1 hypothetical protein YP_859253.1 4125044 R 405955 CDS YP_859254.1 117625931 4495286 complement(4125985..4126836) 1 NC_008563.1 aldolase 4126836 4495286 APECO1_2802 Escherichia coli APEC O1 aldolase YP_859254.1 4125985 R 405955 CDS YP_859255.1 117625932 4495287 complement(4126848..4127939) 1 NC_008563.1 PTS enzyme-II fructose 4127939 4495287 APECO1_2801 Escherichia coli APEC O1 PTS enzyme-II fructose YP_859255.1 4126848 R 405955 CDS YP_859256.1 117625933 4495288 complement(4127964..4128278) 1 NC_008563.1 PTS system, fructose-like-2 IIB component 1 4128278 4495288 APECO1_2800 Escherichia coli APEC O1 PTS system, fructose-like-2 IIB component 1 YP_859256.1 4127964 R 405955 CDS YP_859257.1 117625934 4495769 complement(4128296..4128766) 1 NC_008563.1 phosphotransferase system (PTS), fructose-specific 4128766 4495769 APECO1_2799 Escherichia coli APEC O1 phosphotransferase system (PTS), fructose-specific YP_859257.1 4128296 R 405955 CDS YP_859258.1 117625935 4495770 complement(4128793..4130346) 1 NC_008563.1 transcriptional antiterminator 4130346 4495770 APECO1_2798 Escherichia coli APEC O1 transcriptional antiterminator YP_859258.1 4128793 R 405955 CDS YP_859259.1 117625936 4495771 complement(4130641..4132959) 1 NC_008563.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 4132959 yicI 4495771 yicI Escherichia coli APEC O1 alpha-xylosidase YP_859259.1 4130641 R 405955 CDS YP_859260.1 117625937 4495772 complement(4132969..4134408) 1 NC_008563.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4134408 yicJ 4495772 yicJ Escherichia coli APEC O1 transporter YP_859260.1 4132969 R 405955 CDS YP_859261.1 117625938 4495773 4134662..4135828 1 NC_008563.1 virulence protein RhuM; hypothetical protein 4135828 4495773 APECO1_2795 Escherichia coli APEC O1 hypothetical protein YP_859261.1 4134662 D 405955 CDS YP_859262.1 117625939 4495774 4136398..4136766 1 NC_008563.1 hypothetical protein 4136766 4495774 APECO1_2794 Escherichia coli APEC O1 hypothetical protein YP_859262.1 4136398 D 405955 CDS YP_859263.1 117625940 4495775 4137009..4137986 1 NC_008563.1 hypothetical protein 4137986 yicL 4495775 yicL Escherichia coli APEC O1 hypothetical protein YP_859263.1 4137009 D 405955 CDS YP_859264.1 117625941 4495776 complement(4137990..4138808) 1 NC_008563.1 hypothetical protein 4138808 nlpA 4495776 nlpA Escherichia coli APEC O1 hypothetical protein YP_859264.1 4137990 R 405955 CDS YP_859265.1 117625942 4495777 4138961..4139323 1 NC_008563.1 hypothetical protein 4139323 yicS 4495777 yicS Escherichia coli APEC O1 hypothetical protein YP_859265.1 4138961 D 405955 CDS YP_859266.2 162317565 4495778 complement(4139364..4140554) 1 NC_008563.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4140554 nepI 4495778 nepI Escherichia coli APEC O1 ribonucleoside transporter YP_859266.2 4139364 R 405955 CDS YP_859267.1 117625944 4495779 complement(4140765..4141244) 1 NC_008563.1 2-methylthioadenine synthetase; hypothetical protein 4141244 yicN 4495779 yicN Escherichia coli APEC O1 hypothetical protein YP_859267.1 4140765 R 405955 CDS YP_859268.1 117625945 4495780 complement(4141270..4142682) 1 NC_008563.1 xanthine/uracil permase YicO 4142682 yicO 4495780 yicO Escherichia coli APEC O1 xanthine/uracil permase YicO YP_859268.1 4141270 R 405955 CDS YP_859269.1 117625946 4495781 4142779..4144545 1 NC_008563.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4144545 ade 4495781 ade Escherichia coli APEC O1 cryptic adenine deaminase YP_859269.1 4142779 D 405955 CDS YP_859270.1 117625947 4495782 complement(4144592..4145983) 1 NC_008563.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4145983 uhpT 4495782 uhpT Escherichia coli APEC O1 sugar phosphate antiporter YP_859270.1 4144592 R 405955 CDS YP_859271.1 117625948 4495783 complement(4146121..4147443) 1 NC_008563.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4147443 uhpC 4495783 uhpC Escherichia coli APEC O1 regulatory protein UhpC YP_859271.1 4146121 R 405955 CDS YP_859272.1 117625949 4495784 complement(4147450..4148952) 1 NC_008563.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4148952 uhpB 4495784 uhpB Escherichia coli APEC O1 sensory histidine kinase UhpB YP_859272.1 4147450 R 405955 CDS YP_859273.1 117625950 4495785 complement(4148952..4149542) 1 NC_008563.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4149542 uhpA 4495785 uhpA Escherichia coli APEC O1 DNA-binding transcriptional activator UhpA YP_859273.1 4148952 R 405955 CDS YP_859274.1 117625951 4495786 complement(4149615..4149905) 1 NC_008563.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4149905 ilvN 4495786 ilvN Escherichia coli APEC O1 acetolactate synthase 1 regulatory subunit YP_859274.1 4149615 R 405955 CDS YP_859275.1 117625952 4495787 complement(4149909..4151597) 1 NC_008563.1 acetolactate synthase catalytic subunit 4151597 ilvB 4495787 ilvB Escherichia coli APEC O1 acetolactate synthase catalytic subunit YP_859275.1 4149909 R 405955 CDS YP_859276.1 117625953 4494776 4151581..4151913 1 NC_008563.1 hypothetical protein 4151913 4494776 APECO1_2780 Escherichia coli APEC O1 hypothetical protein YP_859276.1 4151581 D 405955 CDS YP_859277.1 117625954 4494777 4152196..4153386 1 NC_008563.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4153386 emrD 4494777 emrD Escherichia coli APEC O1 multidrug resistance protein D YP_859277.1 4152196 D 405955 CDS YP_859278.1 117625955 4494778 complement(4153394..4153891) 1 NC_008563.1 hypothetical protein 4153891 yidF 4494778 yidF Escherichia coli APEC O1 hypothetical protein YP_859278.1 4153394 R 405955 CDS YP_859279.1 117625956 4494779 complement(4153888..4154250) 1 NC_008563.1 hypothetical protein 4154250 yidG 4494779 yidG Escherichia coli APEC O1 hypothetical protein YP_859279.1 4153888 R 405955 CDS YP_859280.1 117625957 4494780 complement(4154240..4154647) 1 NC_008563.1 hypothetical protein 4154647 yidH 4494780 yidH Escherichia coli APEC O1 hypothetical protein YP_859280.1 4154240 R 405955 CDS YP_859281.1 117625958 4494781 complement(4154647..4156140) 1 NC_008563.1 sulfatase/phosphatase YidJ 4156140 yidJ 4494781 yidJ Escherichia coli APEC O1 sulfatase/phosphatase YidJ YP_859281.1 4154647 R 405955 CDS YP_859282.1 117625959 4494782 complement(4156137..4157852) 1 NC_008563.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4157852 yidK 4494782 yidK Escherichia coli APEC O1 symporter YidK YP_859282.1 4156137 R 405955 CDS YP_859283.1 117625960 4494783 4157989..4158885 1 NC_008563.1 DNA-binding transcriptional regulator YidL 4158885 yidL 4494783 yidL Escherichia coli APEC O1 DNA-binding transcriptional regulator YidL YP_859283.1 4157989 D 405955 CDS YP_859284.1 117625961 4494784 complement(4158975..4160660) 1 NC_008563.1 hypothetical protein 4160660 yidE 4494784 yidE Escherichia coli APEC O1 hypothetical protein YP_859284.1 4158975 R 405955 CDS YP_859285.2 229775952 4494785 complement(4160833..4161261) 1 NC_008563.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4161261 ibpB 4494785 ibpB Escherichia coli APEC O1 heat shock chaperone IbpB YP_859285.2 4160833 R 405955 CDS YP_859286.1 117625963 4494786 complement(4161373..4161786) 1 NC_008563.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4161786 ibpA 4494786 ibpA Escherichia coli APEC O1 heat shock protein IbpA YP_859286.1 4161373 R 405955 CDS YP_859287.1 117625964 4494787 4162017..4162424 1 NC_008563.1 hypothetical protein 4162424 yidQ 4494787 yidQ Escherichia coli APEC O1 hypothetical protein YP_859287.1 4162017 D 405955 CDS YP_859288.1 117625965 4494788 complement(4162428..4163675) 1 NC_008563.1 hypothetical protein 4163675 yidR 4494788 yidR Escherichia coli APEC O1 hypothetical protein YP_859288.1 4162428 R 405955 CDS YP_859289.1 117625966 4494789 4163722..4164843 1 NC_008563.1 dehydrogenase; FAD/NAD(P)-binding domain; oxidoreductase 4164843 yidS 4494789 yidS Escherichia coli APEC O1 oxidoreductase YP_859289.1 4163722 D 405955 CDS YP_859290.1 117625967 4494790 complement(4164804..4166141) 1 NC_008563.1 D-galactonate transporter 4166141 dgoT 4494790 dgoT Escherichia coli APEC O1 D-galactonate transporter YP_859290.1 4164804 R 405955 CDS YP_859291.1 117625968 4494791 complement(4166216..4167364) 1 NC_008563.1 galactonate dehydratase 4167364 dgoD 4494791 dgoD Escherichia coli APEC O1 galactonate dehydratase YP_859291.1 4166216 R 405955 CDS YP_859292.1 117625969 4494792 complement(4167361..4167978) 1 NC_008563.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4167978 dgoA 4494792 dgoA Escherichia coli APEC O1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_859292.1 4167361 R 405955 CDS YP_859293.1 117625970 4494793 complement(4167962..4168840) 1 NC_008563.1 2-oxo-3-deoxygalactonate kinase DgoK 4168840 dgoK 4494793 dgoK Escherichia coli APEC O1 2-oxo-3-deoxygalactonate kinase DgoK YP_859293.1 4167962 R 405955 CDS YP_859294.1 117625971 4494794 complement(4168837..4169526) 1 NC_008563.1 galactonate operon transcriptional repressor DgoR 4169526 dgoR 4494794 dgoR Escherichia coli APEC O1 galactonate operon transcriptional repressor DgoR YP_859294.1 4168837 R 405955 CDS YP_859295.1 117625972 4494795 4169805..4170461 1 NC_008563.1 hypothetical protein 4170461 4494795 APECO1_2761 Escherichia coli APEC O1 hypothetical protein YP_859295.1 4169805 D 405955 CDS YP_859296.1 117625973 4492310 complement(4170505..4171317) 1 NC_008563.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4171317 yidA 4492310 yidA Escherichia coli APEC O1 sugar phosphatase YP_859296.1 4170505 R 405955 CDS YP_859297.1 117625974 4492311 complement(4171432..4171839) 1 NC_008563.1 hypothetical protein 4171839 yidB 4492311 yidB Escherichia coli APEC O1 hypothetical protein YP_859297.1 4171432 R 405955 CDS YP_859298.1 117625975 4492312 complement(4172070..4174484) 1 NC_008563.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4174484 gyrB 4492312 gyrB Escherichia coli APEC O1 DNA gyrase subunit B YP_859298.1 4172070 R 405955 CDS YP_859299.1 117625976 4492313 complement(4174513..4175586) 1 NC_008563.1 RecF, a recombinational DNA repair ATPase; Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4175586 recF 4492313 recF Escherichia coli APEC O1 recombination protein F YP_859299.1 4174513 R 405955 CDS YP_859300.1 117625977 4492314 complement(4175586..4176686) 1 NC_008563.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4176686 dnaN 4492314 dnaN Escherichia coli APEC O1 DNA polymerase III subunit beta YP_859300.1 4175586 R 405955 CDS YP_859301.1 117625978 4492315 complement(4176691..4178106) 1 NC_008563.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 4178106 dnaA 4492315 dnaA Escherichia coli APEC O1 chromosomal replication initiation protein YP_859301.1 4176691 R 405955 CDS YP_859302.1 117625979 4492316 4178858..4179217 1 NC_008563.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4179217 rnpA 4492316 rnpA Escherichia coli APEC O1 ribonuclease P YP_859302.1 4178858 D 405955 CDS YP_859303.1 117625980 4492317 4179441..4181087 1 NC_008563.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; hypothetical protein 4181087 yidC 4492317 yidC Escherichia coli APEC O1 hypothetical protein YP_859303.1 4179441 D 405955 CDS YP_859304.1 117625981 4492318 4181193..4182557 1 NC_008563.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4182557 trmE 4492318 trmE Escherichia coli APEC O1 tRNA modification GTPase TrmE YP_859304.1 4181193 D 405955 CDS YP_859305.1 117625982 4492319 4183079..4184509 1 NC_008563.1 tryptophan deaminase, PLP-dependent; tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4184509 tnaA 4492319 tnaA Escherichia coli APEC O1 tryptophanase YP_859305.1 4183079 D 405955 CDS YP_859306.1 117625983 4492320 4184601..4185848 1 NC_008563.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4185848 tnaB 4492320 tnaB Escherichia coli APEC O1 tryptophan permease TnaB YP_859306.1 4184601 D 405955 CDS YP_859307.1 117625984 4492322 4185980..4187155 1 NC_008563.1 drug/chloramphenicol transport protein (MFS family); Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4187155 mdtL 4492322 mdtL Escherichia coli APEC O1 multidrug efflux system protein MdtL YP_859307.1 4185980 D 405955 CDS YP_859308.1 117625985 4492323 4187130..4188089 1 NC_008563.1 predicted DNA-binding transcriptional regulator; Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4188089 yidZ 4492323 yidZ Escherichia coli APEC O1 DNA-binding transcriptional regulator YidZ YP_859308.1 4187130 D 405955 CDS YP_859309.1 117625986 4492324 4188234..4188995 1 NC_008563.1 predicted phosphopantetheinyl transferase; hypothetical protein 4188995 yieE 4492324 yieE Escherichia coli APEC O1 hypothetical protein YP_859309.1 4188234 D 405955 CDS YP_859310.1 117625987 4492325 4189017..4189583 1 NC_008563.1 hypothetical protein 4189583 yieF 4492325 yieF Escherichia coli APEC O1 hypothetical protein YP_859310.1 4189017 D 405955 CDS YP_859311.1 117625988 4492326 complement(4189636..4190973) 1 NC_008563.1 membrane/transport protein 4190973 yieG 4492326 yieG Escherichia coli APEC O1 membrane/transport protein YP_859311.1 4189636 R 405955 CDS YP_859312.1 117625989 4492327 4191140..4191805 1 NC_008563.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4191805 yieH 4492327 yieH Escherichia coli APEC O1 6-phosphogluconate phosphatase YP_859312.1 4191140 D 405955 CDS YP_859313.1 117625990 4492328 4191872..4192345 1 NC_008563.1 might be involved in hypersensitivity to nitrofurzone; hypothetical protein 4192345 yieI 4492328 yieI Escherichia coli APEC O1 hypothetical protein YP_859313.1 4191872 D 405955 CDS YP_859314.1 117625991 4495711 complement(4192427..4193149) 1 NC_008563.1 isomerase-like; 6-phosphogluconolactonase 4193149 yieK 4495711 yieK Escherichia coli APEC O1 6-phosphogluconolactonase YP_859314.1 4192427 R 405955 CDS YP_859315.1 117625992 4495712 complement(4193164..4194360) 1 NC_008563.1 xylanase 4194360 yieL 4495712 yieL Escherichia coli APEC O1 xylanase YP_859315.1 4193164 R 405955 CDS YP_859316.1 117625993 4495713 complement(4194360..4195976) 1 NC_008563.1 carbohydrate-specific outer membrane porin, cryptic 4195976 bglH 4495713 bglH Escherichia coli APEC O1 carbohydrate-specific outer membrane porin, cryptic YP_859316.1 4194360 R 405955 CDS YP_859317.1 117625994 4495714 complement(4196062..4197456) 1 NC_008563.1 6-phospho-beta-glucosidase 4197456 bglB 4495714 bglB Escherichia coli APEC O1 6-phospho-beta-glucosidase YP_859317.1 4196062 R 405955 CDS YP_859318.1 117625995 4495715 complement(4197475..4199349) 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 4199349 bglF 4495715 bglF Escherichia coli APEC O1 PTS system beta-glucoside-specific transporter subunit IIABC YP_859318.1 4197475 R 405955 CDS YP_859319.1 117625996 4495716 complement(4199483..4200319) 1 NC_008563.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4200319 bglG 4495716 bglG Escherichia coli APEC O1 transcriptional antiterminator BglG YP_859319.1 4199483 R 405955 CDS YP_859320.1 117625997 4495717 complement(4200605..4201330) 1 NC_008563.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4201330 phoU 4495717 phoU Escherichia coli APEC O1 transcriptional regulator PhoU YP_859320.1 4200605 R 405955 CDS YP_859321.1 117625998 4495718 complement(4201345..4202118) 1 NC_008563.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4202118 pstB 4495718 pstB Escherichia coli APEC O1 phosphate transporter ATP-binding protein YP_859321.1 4201345 R 405955 CDS YP_859322.1 117625999 4495719 complement(4202209..4203099) 1 NC_008563.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4203099 pstA 4495719 pstA Escherichia coli APEC O1 phosphate transporter permease subunit PtsA YP_859322.1 4202209 R 405955 CDS YP_859323.1 117626000 4495720 complement(4203099..4204058) 1 NC_008563.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4204058 pstC 4495720 pstC Escherichia coli APEC O1 phosphate transporter permease subunit PstC YP_859323.1 4203099 R 405955 CDS YP_859324.1 117626001 4495721 complement(4204145..4205185) 1 NC_008563.1 periplasmic-binding component of ABC superfamily; phosphate ABC transporter substrate-binding protein 4205185 pstS 4495721 pstS Escherichia coli APEC O1 phosphate ABC transporter substrate-binding protein YP_859324.1 4204145 R 405955 CDS YP_859325.1 117626002 4495722 complement(4205504..4207333) 1 NC_008563.1 GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4207333 glmS 4495722 glmS Escherichia coli APEC O1 glucosamine--fructose-6-phosphate aminotransferase YP_859325.1 4205504 R 405955 CDS YP_859326.1 117626003 4495723 complement(4207494..4208864) 1 NC_008563.1 GlmU; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4208864 glmU 4495723 glmU Escherichia coli APEC O1 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_859326.1 4207494 R 405955 CDS YP_859327.1 117626004 4495724 4209110..4209661 1 NC_008563.1 hypothetical protein 4209661 4495724 APECO1_2730 Escherichia coli APEC O1 hypothetical protein YP_859327.1 4209110 D 405955 CDS YP_859328.1 117626005 4495725 complement(4209658..4211040) 1 NC_008563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4211040 atpD 4495725 atpD Escherichia coli APEC O1 F0F1 ATP synthase subunit beta YP_859328.1 4209658 R 405955 CDS YP_859329.1 117626006 4495726 complement(4211067..4211930) 1 NC_008563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4211930 atpG 4495726 atpG Escherichia coli APEC O1 F0F1 ATP synthase subunit gamma YP_859329.1 4211067 R 405955 CDS YP_859330.1 117626007 4495727 4212086..4213669 1 NC_008563.1 hypothetical protein 4213669 4495727 APECO1_2727 Escherichia coli APEC O1 hypothetical protein YP_859330.1 4212086 D 405955 CDS YP_859331.1 117626008 4495728 4213775..4214446 1 NC_008563.1 hypothetical protein 4214446 4495728 APECO1_2726 Escherichia coli APEC O1 hypothetical protein YP_859331.1 4213775 D 405955 CDS YP_859332.1 117626009 4495729 complement(4214901..4215716) 1 NC_008563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4215716 atpB 4495729 atpB Escherichia coli APEC O1 F0F1 ATP synthase subunit A YP_859332.1 4214901 R 405955 CDS YP_859333.1 117626010 4495730 complement(4215725..4216117) 1 NC_008563.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4216117 atpI 4495730 atpI Escherichia coli APEC O1 F0F1 ATP synthase subunit I YP_859333.1 4215725 R 405955 CDS YP_859334.1 117626011 4491978 complement(4216722..4217345) 1 NC_008563.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4217345 gidB 4491978 gidB Escherichia coli APEC O1 16S rRNA methyltransferase GidB YP_859334.1 4216722 R 405955 CDS YP_859335.1 117626012 4491979 complement(4217409..4219298) 1 NC_008563.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4219298 gidA 4491979 gidA Escherichia coli APEC O1 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_859335.1 4217409 R 405955 CDS YP_859336.1 117626013 4491980 complement(4219677..4220120) 1 NC_008563.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4220120 mioC 4491980 mioC Escherichia coli APEC O1 flavodoxin YP_859336.1 4219677 R 405955 CDS YP_859337.1 117626014 4491981 complement(4220210..4220668) 1 NC_008563.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; AsnC family transcriptional regulator 4220668 asnC 4491981 asnC Escherichia coli APEC O1 AsnC family transcriptional regulator YP_859337.1 4220210 R 405955 CDS YP_859338.1 117626015 4491982 4220820..4221812 1 NC_008563.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4221812 asnA 4491982 asnA Escherichia coli APEC O1 asparagine synthetase AsnA YP_859338.1 4220820 D 405955 CDS YP_859339.1 117626016 4491983 complement(4221817..4223268) 1 NC_008563.1 predicted von Willibrand factor-containing protein; contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4223268 yieM 4491983 yieM Escherichia coli APEC O1 hypothetical protein YP_859339.1 4221817 R 405955 CDS YP_859340.1 117626017 4491984 complement(4223262..4224758) 1 NC_008563.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4224758 yieN 4491984 yieN Escherichia coli APEC O1 regulatory ATPase RavA YP_859340.1 4223262 R 405955 CDS YP_859341.1 117626018 4491985 4224981..4226849 1 NC_008563.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4226849 trkD 4491985 trkD Escherichia coli APEC O1 potassium transport protein Kup YP_859341.1 4224981 D 405955 CDS YP_859342.2 229775951 4491986 4227016..4227435 1 NC_008563.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4227435 rbsD 4491986 rbsD Escherichia coli APEC O1 D-ribose pyranase YP_859342.2 4227016 D 405955 CDS YP_859343.1 117626020 4491987 4227443..4228948 1 NC_008563.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4228948 rbsA 4491987 rbsA Escherichia coli APEC O1 D-ribose transporter ATP-binding protein YP_859343.1 4227443 D 405955 CDS YP_859344.1 117626021 4491988 4228953..4229918 1 NC_008563.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4229918 rbsC 4491988 rbsC Escherichia coli APEC O1 ribose ABC transporter permease YP_859344.1 4228953 D 405955 CDS YP_859345.1 117626022 4491989 4229943..4230833 1 NC_008563.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4230833 rbsB 4491989 rbsB Escherichia coli APEC O1 D-ribose transporter subunit RbsB YP_859345.1 4229943 D 405955 CDS YP_859346.1 117626023 4491990 4230932..4231888 1 NC_008563.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4231888 rbsK 4491990 rbsK Escherichia coli APEC O1 ribokinase YP_859346.1 4230932 D 405955 CDS YP_859347.1 117626024 4491991 4231901..4232884 1 NC_008563.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4232884 rbsR 4491991 rbsR Escherichia coli APEC O1 transcriptional repressor RbsR YP_859347.1 4231901 D 405955 CDS YP_859348.1 117626025 4491992 complement(4232850..4234277) 1 NC_008563.1 transporter 4234277 yieO 4491992 yieO Escherichia coli APEC O1 transporter YP_859348.1 4232850 R 405955 CDS YP_859349.1 117626026 4491993 complement(4234300..4234992) 1 NC_008563.1 transcriptional regulator 4234992 yieP 4491993 yieP Escherichia coli APEC O1 transcriptional regulator YP_859349.1 4234300 R 405955 CDS YP_859351.1 117626028 4491995 complement(4240793..4241632) 1 NC_008563.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4241632 hdfR 4491995 hdfR Escherichia coli APEC O1 transcriptional regulator HdfR YP_859351.1 4240793 R 405955 CDS YP_859352.1 117626029 4491996 4241751..4242089 1 NC_008563.1 hypothetical protein 4242089 4491996 APECO1_2705 Escherichia coli APEC O1 hypothetical protein YP_859352.1 4241751 D 405955 CDS YP_859353.1 117626030 4492990 complement(4242114..4243664) 1 NC_008563.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 4243664 yifB 4492990 yifB Escherichia coli APEC O1 ATP-dependent protease YP_859353.1 4242114 R 405955 CDS YP_859354.1 117626031 4492991 4244225..4245871 1 NC_008563.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4245871 ilvG 4492991 ilvG Escherichia coli APEC O1 acetolactate synthase 2 catalytic subunit YP_859354.1 4244225 D 405955 CDS YP_859355.1 117626032 4492992 4245868..4246131 1 NC_008563.1 acetolactate synthase 2 regulatory subunit 4246131 ilvM 4492992 ilvM Escherichia coli APEC O1 acetolactate synthase 2 regulatory subunit YP_859355.1 4245868 D 405955 CDS YP_859356.1 117626033 4492993 4246151..4247080 1 NC_008563.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4247080 ilvE 4492993 ilvE Escherichia coli APEC O1 branched-chain amino acid aminotransferase YP_859356.1 4246151 D 405955 CDS YP_859357.1 117626034 4492994 4247145..4248995 1 NC_008563.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4248995 ilvD 4492994 ilvD Escherichia coli APEC O1 dihydroxy-acid dehydratase YP_859357.1 4247145 D 405955 CDS YP_859358.1 117626035 4492995 4248995..4250542 1 NC_008563.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4250542 ilvA 4492995 ilvA Escherichia coli APEC O1 threonine dehydratase YP_859358.1 4248995 D 405955 CDS YP_859359.1 117626036 4492996 complement(4250539..4251513) 1 NC_008563.1 DNA-binding transcriptional dual regulator; participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4251513 ilvY 4492996 ilvY Escherichia coli APEC O1 DNA-binding transcriptional regulator IlvY YP_859359.1 4250539 R 405955 CDS YP_859360.1 117626037 4492997 4251579..4253054 1 NC_008563.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4253054 ilvC 4492997 ilvC Escherichia coli APEC O1 ketol-acid reductoisomerase YP_859360.1 4251579 D 405955 CDS YP_859361.1 117626038 4492998 complement(4253100..4253381) 1 NC_008563.1 peptidyl-prolyl cis-trans isomerase C 4253381 ppiC 4492998 ppiC Escherichia coli APEC O1 peptidyl-prolyl cis-trans isomerase C YP_859361.1 4253100 R 405955 CDS YP_859362.1 117626039 4492999 4253468..4255489 1 NC_008563.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4255489 rep 4492999 rep Escherichia coli APEC O1 ATP-dependent DNA helicase Rep YP_859362.1 4253468 D 405955 CDS YP_859363.1 117626040 4493000 complement(4255536..4257029) 1 NC_008563.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4257029 gppA 4493000 gppA Escherichia coli APEC O1 guanosine pentaphosphate phosphohydrolase YP_859363.1 4255536 R 405955 CDS YP_859364.1 117626041 4493001 complement(4257156..4258421) 1 NC_008563.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4258421 rhlB 4493001 rhlB Escherichia coli APEC O1 ATP-dependent RNA helicase RhlB YP_859364.1 4257156 R 405955 CDS YP_859365.1 117626042 4493002 complement(4258546..4258938) 1 NC_008563.1 hypothetical protein 4258938 4493002 APECO1_2692 Escherichia coli APEC O1 hypothetical protein YP_859365.1 4258546 R 405955 CDS YP_859366.1 117626043 4493003 4259136..4260467 1 NC_008563.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4260467 rho 4493003 rho Escherichia coli APEC O1 transcription termination factor Rho YP_859366.1 4259136 D 405955 CDS YP_859367.1 117626044 4493004 4260707..4261810 1 NC_008563.1 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase 4261810 rfe 4493004 rfe Escherichia coli APEC O1 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase YP_859367.1 4260707 D 405955 CDS YP_859368.1 117626045 4493005 4261822..4262868 1 NC_008563.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4262868 wzzE 4493005 wzzE Escherichia coli APEC O1 lipopolysaccharide biosynthesis protein WzzE YP_859368.1 4261822 D 405955 CDS YP_859369.1 117626046 4493006 4262882..4264054 1 NC_008563.1 UDP-N-acetylglucosamine 2-epimerase 4264054 rffE 4493006 rffE Escherichia coli APEC O1 UDP-N-acetylglucosamine 2-epimerase YP_859369.1 4262882 D 405955 CDS YP_859370.1 117626047 4493007 4264051..4265313 1 NC_008563.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4265313 wecC 4493007 wecC Escherichia coli APEC O1 UDP-N-acetyl-D-mannosamine dehydrogenase YP_859370.1 4264051 D 405955 CDS YP_859371.1 117626048 4493008 4265313..4266380 1 NC_008563.1 dTDP-glucose 4,6-dehydratase 4266380 rffG 4493008 rffG Escherichia coli APEC O1 dTDP-glucose 4,6-dehydratase YP_859371.1 4265313 D 405955 CDS YP_859372.1 117626049 4493009 4266399..4267280 1 NC_008563.1 glucose-1-phosphate thymidylyltransferase; lipopolysaccharide biosynthesis protein RffH 4267280 rffH 4493009 rffH Escherichia coli APEC O1 lipopolysaccharide biosynthesis protein RffH YP_859372.1 4266399 D 405955 CDS YP_859373.1 117626050 4495445 4267258..4267932 1 NC_008563.1 TDP-fucosamine acetyltransferase 4267932 rffC 4495445 rffC Escherichia coli APEC O1 TDP-fucosamine acetyltransferase YP_859373.1 4267258 D 405955 CDS YP_859374.1 117626051 4495446 4267937..4269067 1 NC_008563.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4269067 rffA 4495446 rffA Escherichia coli APEC O1 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_859374.1 4267937 D 405955 CDS YP_859375.1 117626052 4495447 4269069..4270319 1 NC_008563.1 O-antigen translocase 4270319 wzxE 4495447 wzxE Escherichia coli APEC O1 O-antigen translocase YP_859375.1 4269069 D 405955 CDS YP_859376.1 117626053 4495448 4270316..4271395 1 NC_008563.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4271395 rffT 4495448 rffT Escherichia coli APEC O1 4-alpha-L-fucosyltransferase YP_859376.1 4270316 D 405955 CDS YP_859377.1 117626054 4495449 4271392..4272744 1 NC_008563.1 enterobacterial common antigen polymerase; common antigen polymerase 4272744 wecF 4495449 wecF Escherichia coli APEC O1 common antigen polymerase YP_859377.1 4271392 D 405955 CDS YP_859378.1 117626055 4495450 4272747..4273487 1 NC_008563.1 UDP-N-acetyl-D-mannosaminuronic acid transferase 4273487 wecG 4495450 wecG Escherichia coli APEC O1 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_859378.1 4272747 D 405955 CDS YP_859379.1 117626056 4495451 4273678..4275063 1 NC_008563.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4275063 yifK 4495451 yifK Escherichia coli APEC O1 transporter YP_859379.1 4273678 D 405955 CDS YP_859380.1 117626057 4495452 4275749..4276984 1 NC_008563.1 regulator of arylsulfatase activity 4276984 aslB 4495452 aslB Escherichia coli APEC O1 regulator of arylsulfatase activity YP_859380.1 4275749 D 405955 CDS YP_859381.1 117626058 4495453 complement(4277142..4278797) 1 NC_008563.1 arylsulfatase-like enzyme 4278797 aslA 4495453 aslA Escherichia coli APEC O1 arylsulfatase-like enzyme YP_859381.1 4277142 R 405955 CDS YP_859382.1 117626059 4495454 complement(4279476..4280672) 1 NC_008563.1 protoheme IX biogenesis protein 4280672 hemY 4495454 hemY Escherichia coli APEC O1 protoheme IX biogenesis protein YP_859382.1 4279476 R 405955 CDS YP_859383.1 117626060 4495455 complement(4280675..4281868) 1 NC_008563.1 uroporphyrinogen III C-methyltransferase 4281868 hemX 4495455 hemX Escherichia coli APEC O1 uroporphyrinogen III C-methyltransferase YP_859383.1 4280675 R 405955 CDS YP_859384.1 117626061 4495456 complement(4281890..4282630) 1 NC_008563.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4282630 hemD 4495456 hemD Escherichia coli APEC O1 uroporphyrinogen-III synthase YP_859384.1 4281890 R 405955 CDS YP_859385.1 117626062 4495457 complement(4282627..4283589) 1 NC_008563.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4283589 hemC 4495457 hemC Escherichia coli APEC O1 porphobilinogen deaminase YP_859385.1 4282627 R 405955 CDS YP_859386.2 229775950 4495458 4283955..4286501 1 NC_008563.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4286501 cyaA 4495458 cyaA Escherichia coli APEC O1 adenylate cyclase YP_859386.2 4283955 D 405955 CDS YP_859387.1 117626064 4495459 complement(4286541..4286861) 1 NC_008563.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4286861 cyaY 4495459 cyaY Escherichia coli APEC O1 frataxin-like protein YP_859387.1 4286541 R 405955 CDS YP_859388.1 117626065 4495460 complement(4286909..4288225) 1 NC_008563.1 hypothetical protein 4288225 4495460 APECO1_2670 Escherichia coli APEC O1 hypothetical protein YP_859388.1 4286909 R 405955 CDS YP_859389.1 117626066 4495461 complement(4288222..4288791) 1 NC_008563.1 hypothetical protein 4288791 4495461 APECO1_2669 Escherichia coli APEC O1 hypothetical protein YP_859389.1 4288222 R 405955 CDS YP_859390.1 117626067 4495462 complement(4288876..4289721) 1 NC_008563.1 hypothetical protein 4289721 4495462 APECO1_2668 Escherichia coli APEC O1 hypothetical protein YP_859390.1 4288876 R 405955 CDS YP_859391.1 117626068 4495463 4290117..4290944 1 NC_008563.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4290944 dapF 4495463 dapF Escherichia coli APEC O1 diaminopimelate epimerase YP_859391.1 4290117 D 405955 CDS YP_859392.1 117626069 4492066 4290941..4291648 1 NC_008563.1 hypothetical protein 4291648 yigA 4492066 yigA Escherichia coli APEC O1 hypothetical protein YP_859392.1 4290941 D 405955 CDS YP_859393.1 117626070 4492067 4291645..4292541 1 NC_008563.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4292541 xerC 4492067 xerC Escherichia coli APEC O1 site-specific tyrosine recombinase XerC YP_859393.1 4291645 D 405955 CDS YP_859394.1 117626071 4492068 4292541..4293257 1 NC_008563.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4293257 yigB 4492068 yigB Escherichia coli APEC O1 flavin mononucleotide phosphatase YP_859394.1 4292541 D 405955 CDS YP_859395.1 117626072 4492069 4293341..4295503 1 NC_008563.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4295503 uvrD 4492069 uvrD Escherichia coli APEC O1 DNA-dependent helicase II YP_859395.1 4293341 D 405955 CDS YP_859396.1 117626073 4492070 complement(4295548..4296450) 1 NC_008563.1 hypothetical protein 4296450 4492070 APECO1_2662 Escherichia coli APEC O1 hypothetical protein YP_859396.1 4295548 R 405955 CDS YP_859397.1 117626074 4492071 complement(4296533..4297297) 1 NC_008563.1 hypothetical protein 4297297 yigE 4492071 yigE Escherichia coli APEC O1 hypothetical protein YP_859397.1 4296533 R 405955 CDS YP_859398.1 117626075 4492072 4297667..4298617 1 NC_008563.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4298617 corA 4492072 corA Escherichia coli APEC O1 magnesium/nickel/cobalt transporter CorA YP_859398.1 4297667 D 405955 CDS YP_859399.1 117626076 4492073 complement(4298653..4299150) 1 NC_008563.1 hypothetical protein 4299150 4492073 APECO1_2659 Escherichia coli APEC O1 hypothetical protein YP_859399.1 4298653 R 405955 CDS YP_859400.1 117626077 4492074 complement(4299147..4299995) 1 NC_008563.1 hypothetical protein 4299995 4492074 APECO1_2658 Escherichia coli APEC O1 hypothetical protein YP_859400.1 4299147 R 405955 CDS YP_859401.1 117626078 4492075 complement(4300306..4301196) 1 NC_008563.1 chloramphenical resistance permease 4301196 rarD 4492075 rarD Escherichia coli APEC O1 chloramphenical resistance permease YP_859401.1 4300306 R 405955 CDS YP_859402.1 117626079 4492076 complement(4301248..4301733) 1 NC_008563.1 hypothetical protein 4301733 yigI 4492076 yigI Escherichia coli APEC O1 hypothetical protein YP_859402.1 4301248 R 405955 CDS YP_859403.1 117626080 4492077 4301880..4302749 1 NC_008563.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4302749 pldA 4492077 pldA Escherichia coli APEC O1 phospholipase A YP_859403.1 4301880 D 405955 CDS YP_859404.1 117626081 4492078 4302868..4304703 1 NC_008563.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4304703 recQ 4492078 recQ Escherichia coli APEC O1 ATP-dependent DNA helicase RecQ YP_859404.1 4302868 D 405955 CDS YP_859405.1 117626082 4492079 4304767..4305387 1 NC_008563.1 threonine efflux system 4305387 rhtC 4492079 rhtC Escherichia coli APEC O1 threonine efflux system YP_859405.1 4304767 D 405955 CDS YP_859406.1 117626083 4492080 complement(4305448..4306068) 1 NC_008563.1 homoserine/homoserine lactone efflux protein 4306068 rhtB 4492080 rhtB Escherichia coli APEC O1 homoserine/homoserine lactone efflux protein YP_859406.1 4305448 R 405955 CDS YP_859407.1 117626084 4492081 4306179..4307201 1 NC_008563.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4307201 pldB 4492081 pldB Escherichia coli APEC O1 lysophospholipase L2 YP_859407.1 4306179 D 405955 CDS YP_859408.1 117626085 4492082 4307092..4308009 1 NC_008563.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4308009 4492082 APECO1_2650 Escherichia coli APEC O1 sugar phosphatase YP_859408.1 4307092 D 405955 CDS YP_859409.1 117626086 4492083 4308085..4308984 1 NC_008563.1 hypothetical protein 4308984 yigM 4492083 yigM Escherichia coli APEC O1 hypothetical protein YP_859409.1 4308085 D 405955 CDS YP_859410.1 117626087 4492084 complement(4308872..4309825) 1 NC_008563.1 regulator for metE and metH; DNA-binding transcriptional activator, homocysteine-binding 4309825 metR 4492084 metR Escherichia coli APEC O1 DNA-binding transcriptional activator, homocysteine-binding YP_859410.1 4308872 R 405955 CDS YP_859411.1 117626088 4492085 4309943..4312204 1 NC_008563.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4312204 metE 4492085 metE Escherichia coli APEC O1 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_859411.1 4309943 D 405955 CDS YP_859412.1 117626089 4492913 complement(4312693..4312950) 1 NC_008563.1 hypothetical protein 4312950 4492913 APECO1_2646 Escherichia coli APEC O1 hypothetical protein YP_859412.1 4312693 R 405955 CDS YP_859413.1 117626090 4492914 complement(4312947..4313438) 1 NC_008563.1 hypothetical protein 4313438 4492914 APECO1_2645 Escherichia coli APEC O1 hypothetical protein YP_859413.1 4312947 R 405955 CDS YP_859414.1 117626091 4492915 complement(4313787..4314080) 1 NC_008563.1 hypothetical protein 4314080 4492915 APECO1_2644 Escherichia coli APEC O1 hypothetical protein YP_859414.1 4313787 R 405955 CDS YP_859415.1 117626092 4492916 4314532..4315122 1 NC_008563.1 sugar isomerase 4315122 4492916 APECO1_2643 Escherichia coli APEC O1 sugar isomerase YP_859415.1 4314532 D 405955 CDS YP_859416.1 117626093 4492917 4315164..4316672 1 NC_008563.1 PTS system, glucose-specific IIBC component 4316672 4492917 APECO1_2642 Escherichia coli APEC O1 PTS system, glucose-specific IIBC component YP_859416.1 4315164 D 405955 CDS YP_859417.1 117626094 4492918 4316723..4318720 1 NC_008563.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4318720 4492918 APECO1_2641 Escherichia coli APEC O1 transketolase YP_859417.1 4316723 D 405955 CDS YP_859418.1 117626095 4492919 complement(4318750..4319595) 1 NC_008563.1 transcriptional regulatory protein 4319595 4492919 APECO1_2640 Escherichia coli APEC O1 transcriptional regulatory protein YP_859418.1 4318750 R 405955 CDS YP_859419.1 117626096 4492920 complement(4319796..4320701) 1 NC_008563.1 transcriptional regulatory protein 4320701 4492920 APECO1_2639 Escherichia coli APEC O1 transcriptional regulatory protein YP_859419.1 4319796 R 405955 CDS YP_859420.1 117626097 4492921 complement(4320779..4322002) 1 NC_008563.1 cytosine/purines uracil thiamine allantoin permease 4322002 4492921 APECO1_2638 Escherichia coli APEC O1 cytosine/purines uracil thiamine allantoin permease YP_859420.1 4320779 R 405955 CDS YP_859421.1 117626098 4492922 complement(4322028..4322417) 1 NC_008563.1 hypothetical protein 4322417 4492922 APECO1_2637 Escherichia coli APEC O1 hypothetical protein YP_859421.1 4322028 R 405955 CDS YP_859422.2 162317564 4492923 complement(4322434..4323390) 1 NC_008563.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4323390 4492923 APECO1_2636 Escherichia coli APEC O1 carbamate kinase YP_859422.2 4322434 R 405955 CDS YP_859423.1 117626100 4492924 complement(4323383..4324858) 1 NC_008563.1 hypothetical protein 4324858 yahG 4492924 yahG Escherichia coli APEC O1 hypothetical protein YP_859423.1 4323383 R 405955 CDS YP_859424.1 117626101 4492925 complement(4324804..4326363) 1 NC_008563.1 hypothetical protein 4326363 yahF 4492925 yahF Escherichia coli APEC O1 hypothetical protein YP_859424.1 4324804 R 405955 CDS YP_859425.1 117626102 4492926 complement(4326458..4327318) 1 NC_008563.1 hypothetical protein 4327318 yahE 4492926 yahE Escherichia coli APEC O1 hypothetical protein YP_859425.1 4326458 R 405955 CDS YP_859426.1 117626103 4492927 complement(4327324..4327992) 1 NC_008563.1 isochorismatase hydrolase 4327992 4492927 APECO1_2632 Escherichia coli APEC O1 isochorismatase hydrolase YP_859426.1 4327324 R 405955 CDS YP_859427.1 117626104 4492928 complement(4328249..4329124) 1 NC_008563.1 dienelactone hydrolase 4329124 4492928 APECO1_2631 Escherichia coli APEC O1 dienelactone hydrolase YP_859427.1 4328249 R 405955 CDS YP_859428.1 117626105 4492929 4329320..4330084 1 NC_008563.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4330084 udp 4492929 udp Escherichia coli APEC O1 uridine phosphorylase YP_859428.1 4329320 D 405955 CDS YP_859429.1 117626106 4492930 complement(4330119..4331609) 1 NC_008563.1 hypothetical protein 4331609 4492930 APECO1_2629 Escherichia coli APEC O1 hypothetical protein YP_859429.1 4330119 R 405955 CDS YP_859430.1 117626107 4492931 complement(4331622..4332128) 1 NC_008563.1 hypothetical protein 4332128 4492931 APECO1_2628 Escherichia coli APEC O1 hypothetical protein YP_859430.1 4331622 R 405955 CDS YP_859431.1 117626108 4494160 complement(4332145..4333119) 1 NC_008563.1 hypothetical protein 4333119 4494160 APECO1_2627 Escherichia coli APEC O1 hypothetical protein YP_859431.1 4332145 R 405955 CDS YP_859432.1 117626109 4494161 4333280..4333804 1 NC_008563.1 aldolase 4333804 4494161 APECO1_2626 Escherichia coli APEC O1 aldolase YP_859432.1 4333280 D 405955 CDS YP_859433.1 117626110 4494162 complement(4333763..4334767) 1 NC_008563.1 2-keto-3-deoxygalactokinase 4334767 4494162 APECO1_2625 Escherichia coli APEC O1 2-keto-3-deoxygalactokinase YP_859433.1 4333763 R 405955 CDS YP_859434.1 117626111 4494163 complement(4334791..4335645) 1 NC_008563.1 transcriptional regulatory protein 4335645 4494163 APECO1_2624 Escherichia coli APEC O1 transcriptional regulatory protein YP_859434.1 4334791 R 405955 CDS YP_859435.1 117626112 4494168 4335775..4337202 1 NC_008563.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4337202 rmuC 4494168 rmuC Escherichia coli APEC O1 DNA recombination protein RmuC YP_859435.1 4335775 D 405955 CDS YP_859436.1 117626113 4494172 4337297..4338052 1 NC_008563.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4338052 ubiE 4494172 ubiE Escherichia coli APEC O1 ubiquinone/menaquinone biosynthesis methyltransferase YP_859436.1 4337297 D 405955 CDS YP_859437.1 117626114 4494173 4338036..4338671 1 NC_008563.1 hypothetical protein 4338671 yigP 4494173 yigP Escherichia coli APEC O1 hypothetical protein YP_859437.1 4338036 D 405955 CDS YP_859438.1 117626115 4494174 4338668..4340308 1 NC_008563.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4340308 ubiB 4494174 ubiB Escherichia coli APEC O1 ubiquinone biosynthesis protein UbiB YP_859438.1 4338668 D 405955 CDS YP_859439.1 117626116 4494175 4340345..4340656 1 NC_008563.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4340656 tatA 4494175 tatA Escherichia coli APEC O1 twin arginine translocase protein A YP_859439.1 4340345 D 405955 CDS YP_859440.1 117626117 4494176 4340660..4341175 1 NC_008563.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4341175 tatB 4494176 tatB Escherichia coli APEC O1 sec-independent translocase YP_859440.1 4340660 D 405955 CDS YP_859441.1 117626118 4494177 4341178..4341954 1 NC_008563.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4341954 tatC 4494177 tatC Escherichia coli APEC O1 twin-arginine protein translocation system subunit TatC YP_859441.1 4341178 D 405955 CDS YP_859442.1 117626119 4494178 4341984..4342778 1 NC_008563.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4342778 tatD 4494178 tatD Escherichia coli APEC O1 DNase TatD YP_859442.1 4341984 D 405955 CDS YP_859443.1 117626120 4494179 complement(4342775..4343263) 1 NC_008563.1 transcriptional activator RfaH 4343263 rfaH 4494179 rfaH Escherichia coli APEC O1 transcriptional activator RfaH YP_859443.1 4342775 R 405955 CDS YP_859444.1 117626121 4492836 4343430..4344923 1 NC_008563.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4344923 ubiD 4492836 ubiD Escherichia coli APEC O1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_859444.1 4343430 D 405955 CDS YP_859445.1 117626122 4492837 4344969..4345670 1 NC_008563.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4345670 fre 4492837 fre Escherichia coli APEC O1 FMN reductase YP_859445.1 4344969 D 405955 CDS YP_859446.1 117626123 4492838 complement(4345953..4347116) 1 NC_008563.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4347116 fadA 4492838 fadA Escherichia coli APEC O1 3-ketoacyl-CoA thiolase YP_859446.1 4345953 R 405955 CDS YP_859447.1 117626124 4492839 complement(4347126..4349441) 1 NC_008563.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4349441 fadB 4492839 fadB Escherichia coli APEC O1 multifunctional fatty acid oxidation complex subunit alpha YP_859447.1 4347126 R 405955 CDS YP_859448.1 117626125 4492840 4349505..4350836 1 NC_008563.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4350836 pepQ 4492840 pepQ Escherichia coli APEC O1 proline dipeptidase YP_859448.1 4349505 D 405955 CDS YP_859449.1 117626126 4492841 4350833..4351450 1 NC_008563.1 hypothetical protein 4351450 yigZ 4492841 yigZ Escherichia coli APEC O1 hypothetical protein YP_859449.1 4350833 D 405955 CDS YP_859450.1 117626127 4492842 4351489..4352940 1 NC_008563.1 potassium transporter 4352940 trkH 4492842 trkH Escherichia coli APEC O1 potassium transporter YP_859450.1 4351489 D 405955 CDS YP_859451.1 117626128 4492843 4352952..4353497 1 NC_008563.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4353497 hemG 4492843 hemG Escherichia coli APEC O1 protoporphyrinogen oxidase YP_859451.1 4352952 D 405955 CDS YP_859453.1 117626130 4492845 complement(4359077..4359604) 1 NC_008563.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4359604 mobB 4492845 mobB Escherichia coli APEC O1 molybdopterin-guanine dinucleotide biosynthesis protein B YP_859453.1 4359077 R 405955 CDS YP_859454.1 117626131 4492846 complement(4359586..4360170) 1 NC_008563.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4360170 mobA 4492846 mobA Escherichia coli APEC O1 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_859454.1 4359586 R 405955 CDS YP_859455.1 117626132 4492847 4360240..4360509 1 NC_008563.1 hypothetical protein 4360509 4492847 APECO1_2603 Escherichia coli APEC O1 hypothetical protein YP_859455.1 4360240 D 405955 CDS YP_859456.1 117626133 4492848 4360586..4361572 1 NC_008563.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4361572 yihE 4492848 yihE Escherichia coli APEC O1 serine/threonine protein kinase YP_859456.1 4360586 D 405955 CDS YP_859457.1 117626134 4492849 4361589..4362215 1 NC_008563.1 protein disulfide isomerase I 4362215 dsbA 4492849 dsbA Escherichia coli APEC O1 protein disulfide isomerase I YP_859457.1 4361589 D 405955 CDS YP_859458.1 117626135 4492850 4362328..4363800 1 NC_008563.1 hypothetical protein 4363800 yihF 4492850 yihF Escherichia coli APEC O1 hypothetical protein YP_859458.1 4362328 D 405955 CDS YP_859459.1 117626136 4492851 complement(4363841..4364773) 1 NC_008563.1 acyltransferase 4364773 yihG 4492851 yihG Escherichia coli APEC O1 acyltransferase YP_859459.1 4363841 R 405955 CDS YP_859460.1 117626137 4492852 4365137..4367923 1 NC_008563.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4367923 polA 4492852 polA Escherichia coli APEC O1 DNA polymerase I YP_859460.1 4365137 D 405955 CDS YP_859461.1 117626138 4492853 complement(4368305..4368952) 1 NC_008563.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4368952 engB 4492853 engB Escherichia coli APEC O1 ribosome biogenesis GTP-binding protein YsxC YP_859461.1 4368305 R 405955 CDS YP_859462.1 117626139 4492854 4369519..4370028 1 NC_008563.1 hypothetical protein 4370028 yihI 4492854 yihI Escherichia coli APEC O1 hypothetical protein YP_859462.1 4369519 D 405955 CDS YP_859463.1 117626140 4493496 4370211..4371590 1 NC_008563.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4371590 hemN 4493496 hemN Escherichia coli APEC O1 coproporphyrinogen III oxidase YP_859463.1 4370211 D 405955 CDS YP_859464.1 117626141 4493497 complement(4371950..4373359) 1 NC_008563.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4373359 glnG 4493497 glnG Escherichia coli APEC O1 nitrogen regulation protein NR(I) YP_859464.1 4371950 R 405955 CDS YP_859465.1 117626142 4493498 complement(4373371..4374420) 1 NC_008563.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4374420 glnL 4493498 glnL Escherichia coli APEC O1 nitrogen regulation protein NR(II) YP_859465.1 4373371 R 405955 CDS YP_859466.1 117626143 4493499 complement(4374594..4376003) 1 NC_008563.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4376003 glnA 4493499 glnA Escherichia coli APEC O1 glutamine synthetase YP_859466.1 4374594 R 405955 CDS YP_859467.1 117626144 4493500 4376376..4378199 1 NC_008563.1 GTP-binding protein 4378199 bipA 4493500 bipA Escherichia coli APEC O1 GTP-binding protein YP_859467.1 4376376 D 405955 CDS YP_859468.1 117626145 4493501 complement(4378306..4379094) 1 NC_008563.1 similar to DNA-binding transcriptional regulator YihW; regulatory protein 4379094 4493501 APECO1_2590 Escherichia coli APEC O1 regulatory protein YP_859468.1 4378306 R 405955 CDS YP_859469.1 117626146 4493502 complement(4379134..4380081) 1 NC_008563.1 similar to ribokinase YihV; ribokinase family; hypothetical protein 4380081 4493502 APECO1_2589 Escherichia coli APEC O1 hypothetical protein YP_859469.1 4379134 R 405955 CDS YP_859470.1 117626147 4493503 4380133..4381080 1 NC_008563.1 similar to oxidoreductase YihU; hypothetical protein 4381080 4493503 APECO1_2588 Escherichia coli APEC O1 hypothetical protein YP_859470.1 4380133 D 405955 CDS YP_859471.1 117626148 4493504 4381105..4381992 1 NC_008563.1 hypothetical protein 4381992 4493504 APECO1_2587 Escherichia coli APEC O1 hypothetical protein YP_859471.1 4381105 D 405955 CDS YP_859472.1 117626149 4493505 4382025..4383035 1 NC_008563.1 dehydrogenase 4383035 4493505 APECO1_2586 Escherichia coli APEC O1 dehydrogenase YP_859472.1 4382025 D 405955 CDS YP_859473.1 117626150 4493506 4383105..4384538 1 NC_008563.1 major facilitator superfamily; hypothetical protein 4384538 4493506 APECO1_2585 Escherichia coli APEC O1 hypothetical protein YP_859473.1 4383105 D 405955 CDS YP_859474.1 117626151 4493507 4384637..4385986 1 NC_008563.1 major facilitator superfamily; shikimate transporter 4385986 4493507 APECO1_2584 Escherichia coli APEC O1 shikimate transporter YP_859474.1 4384637 D 405955 CDS YP_859475.1 117626152 4493508 4385931..4386863 1 NC_008563.1 hypothetical protein 4386863 4493508 APECO1_2583 Escherichia coli APEC O1 hypothetical protein YP_859475.1 4385931 D 405955 CDS YP_859476.1 117626153 4493509 4386983..4387603 1 NC_008563.1 hydrolase; phosphatase 4387603 4493509 APECO1_2582 Escherichia coli APEC O1 phosphatase YP_859476.1 4386983 D 405955 CDS YP_859477.1 117626154 4493510 4387597..4388469 1 NC_008563.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4388469 rbn 4493510 rbn Escherichia coli APEC O1 ribonuclease BN YP_859477.1 4387597 D 405955 CDS YP_859478.1 117626155 4493511 4388466..4388903 1 NC_008563.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4388903 dtd 4493511 dtd Escherichia coli APEC O1 D-tyrosyl-tRNA(Tyr) deacylase YP_859478.1 4388466 D 405955 CDS YP_859479.1 117626156 4493512 4388900..4389889 1 NC_008563.1 acetyltransferase 4389889 yiiD 4493512 yiiD Escherichia coli APEC O1 acetyltransferase YP_859479.1 4388900 D 405955 CDS YP_859480.1 117626157 4493513 complement(4389953..4390936) 1 NC_008563.1 esterase/lipase/thioesterase domain; lipase 4390936 4493513 APECO1_2578 Escherichia coli APEC O1 lipase YP_859480.1 4389953 R 405955 CDS YP_859481.1 117626158 4493514 4391090..4391401 1 NC_008563.1 hypothetical protein 4391401 4493514 APECO1_2577 Escherichia coli APEC O1 hypothetical protein YP_859481.1 4391090 D 405955 CDS YP_859482.1 117626159 4493515 4391402..4391692 1 NC_008563.1 hypothetical protein 4391692 4493515 APECO1_2576 Escherichia coli APEC O1 hypothetical protein YP_859482.1 4391402 D 405955 CDS YP_859483.1 117626160 4495574 4392051..4392329 1 NC_008563.1 hypothetical protein 4392329 4495574 APECO1_2575 Escherichia coli APEC O1 hypothetical protein YP_859483.1 4392051 D 405955 CDS YP_859484.1 117626161 4495575 complement(4393159..4394088) 1 NC_008563.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4394088 fdhE 4495575 fdhE Escherichia coli APEC O1 formate dehydrogenase accessory protein FdhE YP_859484.1 4393159 R 405955 CDS YP_859485.1 117626162 4495576 complement(4394085..4394720) 1 NC_008563.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4394720 fdoI 4495576 fdoI Escherichia coli APEC O1 formate dehydrogenase-O subunit gamma YP_859485.1 4394085 R 405955 CDS YP_859486.1 117626163 4495577 complement(4394717..4395619) 1 NC_008563.1 formate dehydrogenase-O, Fe-S subunit 4395619 fdoH 4495577 fdoH Escherichia coli APEC O1 formate dehydrogenase-O, Fe-S subunit YP_859486.1 4394717 R 405955 CDS YP_859487.1 117626164 4495578 complement(4395632..4398046) 1 NC_008563.1 authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-O, large subunit 4398046 fdoG 4495578 fdoG Escherichia coli APEC O1 formate dehydrogenase-O, large subunit YP_859487.1 4395632 R 405955 CDS YP_859488.1 117626165 4495579 complement(4398095..4398682) 1 NC_008563.1 authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-O, large subunit 4398682 fdoG 4495579 fdoG Escherichia coli APEC O1 formate dehydrogenase-O, large subunit YP_859488.1 4398095 R 405955 CDS YP_859489.1 117626166 4495580 4398876..4399709 1 NC_008563.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4399709 fdhD 4495580 fdhD Escherichia coli APEC O1 formate dehydrogenase accessory protein YP_859489.1 4398876 D 405955 CDS YP_859490.1 117626167 4495581 4400105..4400485 1 NC_008563.1 hypothetical protein 4400485 yiiG 4495581 yiiG Escherichia coli APEC O1 hypothetical protein YP_859490.1 4400105 D 405955 CDS YP_859491.1 117626168 4495582 4400839..4402233 1 NC_008563.1 porin domain; glycoporin 4402233 4495582 APECO1_2568 Escherichia coli APEC O1 glycoporin YP_859491.1 4400839 D 405955 CDS YP_859492.1 117626169 4495583 complement(4402274..4402588) 1 NC_008563.1 L-rhamnose mutarotase; hypothetical protein 4402588 yiiL 4495583 yiiL Escherichia coli APEC O1 hypothetical protein YP_859492.1 4402274 R 405955 CDS YP_859493.1 117626170 4495584 complement(4402598..4403422) 1 NC_008563.1 rhamnulose-1-phosphate aldolase 4403422 rhaD 4495584 rhaD Escherichia coli APEC O1 rhamnulose-1-phosphate aldolase YP_859493.1 4402598 R 405955 CDS YP_859494.1 117626171 4495585 complement(4403699..4404958) 1 NC_008563.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4404958 rhaA 4495585 rhaA Escherichia coli APEC O1 L-rhamnose isomerase YP_859494.1 4403699 R 405955 CDS YP_859495.1 117626172 4495586 complement(4404955..4406424) 1 NC_008563.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4406424 rhaB 4495586 rhaB Escherichia coli APEC O1 rhamnulokinase YP_859495.1 4404955 R 405955 CDS YP_859496.1 117626173 4495587 4406712..4407548 1 NC_008563.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4407548 rhaS 4495587 rhaS Escherichia coli APEC O1 transcriptional activator RhaS YP_859496.1 4406712 D 405955 CDS YP_859497.1 117626174 4495588 4407532..4408470 1 NC_008563.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4408470 rhaR 4495588 rhaR Escherichia coli APEC O1 transcriptional activator RhaR YP_859497.1 4407532 D 405955 CDS YP_859498.1 117626175 4495589 complement(4408467..4409501) 1 NC_008563.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4409501 rhaT 4495589 rhaT Escherichia coli APEC O1 rhamnose-proton symporter YP_859498.1 4408467 R 405955 CDS YP_859499.1 117626176 4494047 4409780..4410406 1 NC_008563.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4410406 sodA 4494047 sodA Escherichia coli APEC O1 superoxide dismutase YP_859499.1 4409780 D 405955 CDS YP_859500.2 162317563 4494048 4410666..4411649 1 NC_008563.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4411649 kdgT 4494048 kdgT Escherichia coli APEC O1 2-keto-3-deoxygluconate permease YP_859500.2 4410666 D 405955 CDS YP_859501.1 117626178 4494049 4411783..4412472 1 NC_008563.1 hypothetical protein 4412472 yiiM 4494049 yiiM Escherichia coli APEC O1 hypothetical protein YP_859501.1 4411783 D 405955 CDS YP_859502.1 117626179 4494050 complement(4412578..4413951) 1 NC_008563.1 CpxA controls the expression of genes involved in protein folding and degradation; part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4413951 cpxA 4494050 cpxA Escherichia coli APEC O1 two-component sensor protein YP_859502.1 4412578 R 405955 CDS YP_859503.1 117626180 4494051 complement(4413948..4414646) 1 NC_008563.1 CpxR controls the expression of genes involved in protein folding and degradation, DNA-binding response regulator in two-component regulatory system with CpxA; response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4414646 cpxR 4494051 cpxR Escherichia coli APEC O1 DNA-binding transcriptional regulator CpxR YP_859503.1 4413948 R 405955 CDS YP_859504.1 117626181 4494052 4414793..4415296 1 NC_008563.1 periplasmic protein combats stress; repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4415296 cpxP 4494052 cpxP Escherichia coli APEC O1 repressor CpxP YP_859504.1 4414793 D 405955 CDS YP_859505.1 117626182 4494053 4415445..4416347 1 NC_008563.1 transport function, CDF family; member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4416347 fieF 4494053 fieF Escherichia coli APEC O1 ferrous iron efflux protein F YP_859505.1 4415445 D 405955 CDS YP_859506.1 117626183 4494054 4416468..4417490 1 NC_008563.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4417490 pfkA 4494054 pfkA Escherichia coli APEC O1 6-phosphofructokinase YP_859506.1 4416468 D 405955 CDS YP_859507.1 117626184 4494055 4417810..4418799 1 NC_008563.1 sulfate transporter subunit 4418799 sbp 4494055 sbp Escherichia coli APEC O1 sulfate transporter subunit YP_859507.1 4417810 D 405955 CDS YP_859508.1 117626185 4494056 4418717..4419661 1 NC_008563.1 CDP-diacylglycerol pyrophosphatase 4419661 cdh 4494056 cdh Escherichia coli APEC O1 CDP-diacylglycerol pyrophosphatase YP_859508.1 4418717 D 405955 CDS YP_859509.1 117626186 4494057 complement(4419716..4420483) 1 NC_008563.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4420483 tpiA 4494057 tpiA Escherichia coli APEC O1 triosephosphate isomerase YP_859509.1 4419716 R 405955 CDS YP_859510.1 117626187 4494058 complement(4420591..4421190) 1 NC_008563.1 hypothetical protein 4421190 yiiQ 4494058 yiiQ Escherichia coli APEC O1 hypothetical protein YP_859510.1 4420591 R 405955 CDS YP_859511.1 117626188 4494059 4421291..4421731 1 NC_008563.1 hypothetical protein 4421731 yiiR 4494059 yiiR Escherichia coli APEC O1 hypothetical protein YP_859511.1 4421291 D 405955 CDS YP_859512.1 117626189 4494060 4421943..4422242 1 NC_008563.1 hypothetical protein 4422242 yiiS 4494060 yiiS Escherichia coli APEC O1 hypothetical protein YP_859512.1 4421943 D 405955 CDS YP_859513.1 117626190 4494972 4422269..4422697 1 NC_008563.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4422697 yiiT 4494972 yiiT Escherichia coli APEC O1 universal stress protein UspD YP_859513.1 4422269 D 405955 CDS YP_859514.1 117626191 4494973 complement(4422702..4423448) 1 NC_008563.1 ferredoxin-NADP reductase 4423448 fpr 4494973 fpr Escherichia coli APEC O1 ferredoxin-NADP reductase YP_859514.1 4422702 R 405955 CDS YP_859515.1 117626192 4494974 complement(4423545..4424555) 1 NC_008563.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4424555 glpX 4494974 glpX Escherichia coli APEC O1 fructose 1,6-bisphosphatase II YP_859515.1 4423545 R 405955 CDS YP_859516.1 117626193 4494975 complement(4424726..4426255) 1 NC_008563.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4426255 glpK 4494975 glpK Escherichia coli APEC O1 glycerol kinase YP_859516.1 4424726 R 405955 CDS YP_859517.1 117626194 4494976 complement(4426257..4427102) 1 NC_008563.1 glycerol uptake facilitator protein 4427102 glpF 4494976 glpF Escherichia coli APEC O1 glycerol uptake facilitator protein YP_859517.1 4426257 R 405955 CDS YP_859518.1 117626195 4494977 4427914..4428420 1 NC_008563.1 hypothetical protein 4428420 4494977 APECO1_2541 Escherichia coli APEC O1 hypothetical protein YP_859518.1 4427914 D 405955 CDS YP_859519.1 117626196 4494978 complement(4428435..4429361) 1 NC_008563.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4429361 menA 4494978 menA Escherichia coli APEC O1 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_859519.1 4428435 R 405955 CDS YP_859520.1 117626197 4494979 complement(4429428..4430759) 1 NC_008563.1 heat shock protein, homologous to chaperones; heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4430759 hslU 4494979 hslU Escherichia coli APEC O1 ATP-dependent protease ATP-binding subunit HslU YP_859520.1 4429428 R 405955 CDS YP_859521.1 117626198 4494980 complement(4430769..4431299) 1 NC_008563.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4431299 hslV 4494980 hslV Escherichia coli APEC O1 ATP-dependent protease peptidase subunit YP_859521.1 4430769 R 405955 CDS YP_859522.1 117626199 4494981 complement(4431392..4432351) 1 NC_008563.1 cell division protein FtsN 4432351 ftsN 4494981 ftsN Escherichia coli APEC O1 cell division protein FtsN YP_859522.1 4431392 R 405955 CDS YP_859523.1 117626200 4494982 complement(4432443..4433474) 1 NC_008563.1 regulator for deo operon, udp, cdd, tsx, nupC, and nupG; negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4433474 cytR 4494982 cytR Escherichia coli APEC O1 DNA-binding transcriptional regulator CytR YP_859523.1 4432443 R 405955 CDS YP_859524.1 117626201 4494983 complement(4433624..4435894) 1 NC_008563.1 primosomal protein N' (factor Y) directs replication fork assembly at D-loops, ATP-dependent; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4435894 priA 4494983 priA Escherichia coli APEC O1 primosome assembly protein PriA YP_859524.1 4433624 R 405955 CDS YP_859525.1 117626202 4494984 complement(4436298..4436906) 1 NC_008563.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 4436906 yliX 4494984 yliX Escherichia coli APEC O1 peptidoglycan peptidase YP_859525.1 4436298 R 405955 CDS YP_859526.1 117626203 4494985 complement(4436966..4437421) 1 NC_008563.1 repressor of all met genes but metF; when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4437421 metJ 4494985 metJ Escherichia coli APEC O1 transcriptional repressor protein MetJ YP_859526.1 4436966 R 405955 CDS YP_859527.1 117626204 4494986 4437506..4438720 1 NC_008563.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4438720 metB 4494986 metB Escherichia coli APEC O1 cystathionine gamma-synthase YP_859527.1 4437506 D 405955 CDS YP_859528.1 117626205 4494987 4438723..4441155 1 NC_008563.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4441155 metL 4494987 metL Escherichia coli APEC O1 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_859528.1 4438723 D 405955 CDS YP_859529.1 117626206 4494988 complement(4441373..4442233) 1 NC_008563.1 nucleoside-specific channel-forming protein Tsx precursor 4442233 tsx 4494988 tsx Escherichia coli APEC O1 nucleoside-specific channel-forming protein Tsx precursor YP_859529.1 4441373 R 405955 CDS YP_859530.1 117626207 4494989 complement(4442310..4443935) 1 NC_008563.1 metallophosphoesterase; hypothetical protein 4443935 4494989 APECO1_2529 Escherichia coli APEC O1 hypothetical protein YP_859530.1 4442310 R 405955 CDS YP_859531.1 117626208 4494990 complement(4443970..4445523) 1 NC_008563.1 dihydroorotase; hypothetical protein 4445523 4494990 APECO1_2528 Escherichia coli APEC O1 hypothetical protein YP_859531.1 4443970 R 405955 CDS YP_859532.1 117626209 4491557 complement(4445753..4446877) 1 NC_008563.1 hypothetical protein 4446877 4491557 APECO1_2527 Escherichia coli APEC O1 hypothetical protein YP_859532.1 4445753 R 405955 CDS YP_859533.1 117626210 4491558 4447010..4448563 1 NC_008563.1 5'-nucleotidase 4448563 4491558 APECO1_2526 Escherichia coli APEC O1 5'-nucleotidase YP_859533.1 4447010 D 405955 CDS YP_859534.1 117626211 4491559 4448945..4449835 1 NC_008563.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4449835 metF 4491559 metF Escherichia coli APEC O1 5,10-methylenetetrahydrofolate reductase YP_859534.1 4448945 D 405955 CDS YP_859535.1 117626212 4491560 4450164..4452344 1 NC_008563.1 catalase/hydroperoxidase HPI(I) 4452344 katG 4491560 katG Escherichia coli APEC O1 catalase/hydroperoxidase HPI(I) YP_859535.1 4450164 D 405955 CDS YP_859536.1 117626213 4491561 4452372..4453343 1 NC_008563.1 permease 4453343 yijE 4491561 yijE Escherichia coli APEC O1 permease YP_859536.1 4452372 D 405955 CDS YP_859537.1 117626214 4491562 complement(4453370..4453987) 1 NC_008563.1 hypothetical protein 4453987 yijF 4491562 yijF Escherichia coli APEC O1 hypothetical protein YP_859537.1 4453370 R 405955 CDS YP_859538.1 117626215 4491563 complement(4454263..4455405) 1 NC_008563.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4455405 gldA 4491563 gldA Escherichia coli APEC O1 glycerol dehydrogenase YP_859538.1 4454263 R 405955 CDS YP_859539.1 117626216 4491564 complement(4455377..4456039) 1 NC_008563.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4456039 fsaB 4491564 fsaB Escherichia coli APEC O1 fructose-6-phosphate aldolase YP_859539.1 4455377 R 405955 CDS YP_859540.1 117626217 4491565 complement(4456051..4458552) 1 NC_008563.1 PTS family Hpr; phosphoenolpyruvate-protein phosphotransferase PtsA 4458552 ptsA 4491565 ptsA Escherichia coli APEC O1 phosphoenolpyruvate-protein phosphotransferase PtsA YP_859540.1 4456051 R 405955 CDS YP_859541.1 117626218 4491566 4458861..4459940 1 NC_008563.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4459940 fruA 4491566 fruA Escherichia coli APEC O1 fructose-like permease EIIC subunit 2 YP_859541.1 4458861 D 405955 CDS YP_859542.1 117626219 4491567 complement(4459988..4460314) 1 NC_008563.1 hypothetical protein 4460314 4491567 APECO1_2517 Escherichia coli APEC O1 hypothetical protein YP_859542.1 4459988 R 405955 CDS YP_859543.1 117626220 4491568 4460326..4462623 1 NC_008563.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4462623 pflD 4491568 pflD Escherichia coli APEC O1 formate acetyltransferase 2 YP_859543.1 4460326 D 405955 CDS YP_859544.1 117626221 4491569 4462520..4463467 1 NC_008563.1 pyruvate formate lyase II activase 4463467 pflC 4491569 pflC Escherichia coli APEC O1 pyruvate formate lyase II activase YP_859544.1 4462520 D 405955 CDS YP_859545.2 229775949 4491570 4463469..4463810 1 NC_008563.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4463810 frwD 4491570 frwD Escherichia coli APEC O1 fructose-like phosphotransferase EIIB subunit 3 YP_859545.2 4463469 D 405955 CDS YP_859546.1 117626223 4491571 complement(4463797..4464648) 1 NC_008563.1 DNA-binding transcriptional regulator 4464648 yijO 4491571 yijO Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_859546.1 4463797 R 405955 CDS YP_859547.1 117626224 4491572 complement(4464874..4466607) 1 NC_008563.1 sulfatase; hypothetical protein 4466607 yjjP 4491572 yjjP Escherichia coli APEC O1 hypothetical protein YP_859547.1 4464874 R 405955 CDS YP_859548.1 117626225 4491573 complement(4466790..4469441) 1 NC_008563.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4469441 ppc 4491573 ppc Escherichia coli APEC O1 phosphoenolpyruvate carboxylase YP_859548.1 4466790 R 405955 CDS YP_859549.1 117626226 4491574 complement(4469743..4470933) 1 NC_008563.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4470933 argE 4491574 argE Escherichia coli APEC O1 acetylornithine deacetylase YP_859549.1 4469743 R 405955 CDS YP_859550.1 117626227 4491575 4471048..4472052 1 NC_008563.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4472052 argC 4491575 argC Escherichia coli APEC O1 N-acetyl-gamma-glutamyl-phosphate reductase YP_859550.1 4471048 D 405955 CDS YP_859551.1 117626228 4491576 4472027..4472836 1 NC_008563.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4472836 argB 4491576 argB Escherichia coli APEC O1 acetylglutamate kinase YP_859551.1 4472027 D 405955 CDS YP_859552.1 117626229 4491440 4472897..4474270 1 NC_008563.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4474270 argH 4491440 argH Escherichia coli APEC O1 argininosuccinate lyase YP_859552.1 4472897 D 405955 CDS YP_859553.1 117626230 4491441 4474708..4475982 1 NC_008563.1 starvation sensing protein RspA 4475982 rspA 4491441 rspA Escherichia coli APEC O1 starvation sensing protein RspA YP_859553.1 4474708 D 405955 CDS YP_859554.1 117626231 4491442 4476049..4477332 1 NC_008563.1 major facilitator superfamily; hypothetical protein 4477332 yjjL 4491442 yjjL Escherichia coli APEC O1 hypothetical protein YP_859554.1 4476049 D 405955 CDS YP_859555.1 117626232 4491443 4477539..4478501 1 NC_008563.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4478501 oxyR 4491443 oxyR Escherichia coli APEC O1 DNA-binding transcriptional regulator OxyR YP_859555.1 4477539 D 405955 CDS YP_859556.1 117626233 4491444 complement(4478484..4479884) 1 NC_008563.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4479884 udhA 4491444 udhA Escherichia coli APEC O1 soluble pyridine nucleotide transhydrogenase YP_859556.1 4478484 R 405955 CDS YP_859557.1 117626234 4491445 4480214..4481380 1 NC_008563.1 hippuricase 4481380 4491445 APECO1_2502 Escherichia coli APEC O1 hippuricase YP_859557.1 4480214 D 405955 CDS YP_859558.1 117626235 4491446 4481423..4482739 1 NC_008563.1 transporter 4482739 4491446 APECO1_2501 Escherichia coli APEC O1 transporter YP_859558.1 4481423 D 405955 CDS YP_859559.1 117626236 4491447 4482789..4483493 1 NC_008563.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4483493 yijC 4491447 yijC Escherichia coli APEC O1 DNA-binding transcriptional repressor FabR YP_859559.1 4482789 D 405955 CDS YP_859560.1 117626237 4491448 4483493..4483852 1 NC_008563.1 hypothetical protein 4483852 yijD 4491448 yijD Escherichia coli APEC O1 hypothetical protein YP_859560.1 4483493 D 405955 CDS YP_859561.1 117626238 4491449 complement(4483892..4484992) 1 NC_008563.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4484992 trmA 4491449 trmA Escherichia coli APEC O1 tRNA (uracil-5-)-methyltransferase YP_859561.1 4483892 R 405955 CDS YP_859562.2 229775948 4491450 4485361..4487205 1 NC_008563.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4487205 btuB 4491450 btuB Escherichia coli APEC O1 vitamin B12/cobalamin outer membrane transporter YP_859562.2 4485361 D 405955 CDS YP_859563.2 162317562 4491451 4487150..4488007 1 NC_008563.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4488007 murI 4491451 murI Escherichia coli APEC O1 glutamate racemase YP_859563.2 4487150 D 405955 CDS YP_859564.1 117626241 4491452 4493638..4494666 1 NC_008563.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4494666 murB 4491452 murB Escherichia coli APEC O1 UDP-N-acetylenolpyruvoylglucosamine reductase YP_859564.1 4493638 D 405955 CDS YP_859565.1 117626242 4491453 4494663..4495628 1 NC_008563.1 biotin ligase; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4495628 birA 4491453 birA Escherichia coli APEC O1 biotin--protein ligase YP_859565.1 4494663 D 405955 CDS YP_859566.1 117626243 4491454 complement(4495657..4496628) 1 NC_008563.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4496628 coaA 4491454 coaA Escherichia coli APEC O1 pantothenate kinase YP_859566.1 4495657 R 405955 CDS YP_859567.1 117626244 4491455 4497525..4498709 1 NC_008563.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4498709 tufA 4491455 tufA Escherichia coli APEC O1 elongation factor Tu YP_859567.1 4497525 D 405955 CDS YP_859568.1 117626245 4491456 4498939..4499322 1 NC_008563.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4499322 secE 4491456 secE Escherichia coli APEC O1 preprotein translocase subunit SecE YP_859568.1 4498939 D 405955 CDS YP_859569.1 117626246 4491457 4499324..4499869 1 NC_008563.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4499869 nusG 4491457 nusG Escherichia coli APEC O1 transcription antitermination protein NusG YP_859569.1 4499324 D 405955 CDS YP_859570.1 117626247 4491458 complement(4499974..4500975) 1 NC_008563.1 hypothetical protein 4500975 4491458 APECO1_2489 Escherichia coli APEC O1 hypothetical protein YP_859570.1 4499974 R 405955 CDS YP_004770506.1 342515490 11031901 4500028..4500456 1 NC_008563.1 50S ribosomal protein L11 4500456 11031901 APECO1_p1 Escherichia coli APEC O1 50S ribosomal protein L11 YP_004770506.1 4500028 D 405955 CDS YP_004770507.1 342515491 11031903 4500460..4501164 1 NC_008563.1 50S ribosomal protein L1 4501164 11031903 APECO1_p2 Escherichia coli APEC O1 50S ribosomal protein L1 YP_004770507.1 4500460 D 405955 CDS YP_859571.1 117626248 4493792 4501456..4501953 1 NC_008563.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4501953 rplJ 4493792 rplJ Escherichia coli APEC O1 50S ribosomal protein L10 YP_859571.1 4501456 D 405955 CDS YP_859572.1 117626249 4493793 complement(4502005..4502445) 1 NC_008563.1 hypothetical protein 4502445 4493793 APECO1_2487 Escherichia coli APEC O1 hypothetical protein YP_859572.1 4502005 R 405955 CDS YP_859573.1 117626250 4493794 4502672..4506733 1 NC_008563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4506733 rpoB 4493794 rpoB Escherichia coli APEC O1 DNA-directed RNA polymerase subunit beta YP_859573.1 4502672 D 405955 CDS YP_859574.1 117626251 4493795 4506810..4511033 1 NC_008563.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4511033 rpoC 4493795 rpoC Escherichia coli APEC O1 DNA-directed RNA polymerase subunit beta' YP_859574.1 4506810 D 405955 CDS YP_859575.1 117626252 4493796 complement(4511273..4512406) 1 NC_008563.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4512406 thiH 4493796 thiH Escherichia coli APEC O1 thiamine biosynthesis protein ThiH YP_859575.1 4511273 R 405955 CDS YP_859576.2 162317561 4493798 complement(4512403..4513173) 1 NC_008563.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4513173 thiG 4493798 thiG Escherichia coli APEC O1 thiazole synthase YP_859576.2 4512403 R 405955 CDS YP_859577.1 117626254 4493799 complement(4513359..4514207) 1 NC_008563.1 thiazole biosynthesis protein ThiF 4514207 thiF 4493799 thiF Escherichia coli APEC O1 thiazole biosynthesis protein ThiF YP_859577.1 4513359 R 405955 CDS YP_859578.1 117626255 4493800 complement(4514107..4514742) 1 NC_008563.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4514742 thiE 4493800 thiE Escherichia coli APEC O1 thiamine-phosphate pyrophosphorylase YP_859578.1 4514107 R 405955 CDS YP_859579.1 117626256 4493801 complement(4514742..4516637) 1 NC_008563.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4516637 thiC 4493801 thiC Escherichia coli APEC O1 thiamine biosynthesis protein ThiC YP_859579.1 4514742 R 405955 CDS YP_859580.1 117626257 4493802 complement(4516870..4517346) 1 NC_008563.1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ; binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4517346 yjaE 4493802 yjaE Escherichia coli APEC O1 anti-RNA polymerase sigma 70 factor YP_859580.1 4516870 R 405955 CDS YP_859581.1 117626258 4493803 4517441..4518214 1 NC_008563.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4518214 nudC 4493803 nudC Escherichia coli APEC O1 NADH pyrophosphatase YP_859581.1 4517441 D 405955 CDS YP_859582.1 117626259 4493804 4518254..4519318 1 NC_008563.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4519318 hemE 4493804 hemE Escherichia coli APEC O1 uroporphyrinogen decarboxylase YP_859582.1 4518254 D 405955 CDS YP_859583.1 117626260 4493805 4519328..4519999 1 NC_008563.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4519999 nfi 4493805 nfi Escherichia coli APEC O1 endonuclease V YP_859583.1 4519328 D 405955 CDS YP_859584.1 117626261 4493806 4520042..4520632 1 NC_008563.1 hypothetical protein 4520632 yjaG 4493806 yjaG Escherichia coli APEC O1 hypothetical protein YP_859584.1 4520042 D 405955 CDS YP_859585.1 117626262 4493807 4520819..4521091 1 NC_008563.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4521091 4493807 APECO1_2475 Escherichia coli APEC O1 transcriptional regulator HU subunit alpha YP_859585.1 4520819 D 405955 CDS YP_859586.1 117626263 4493808 4521098..4521799 1 NC_008563.1 hypothetical protein 4521799 yjaH 4493808 yjaH Escherichia coli APEC O1 hypothetical protein YP_859586.1 4521098 D 405955 CDS YP_859587.1 117626264 4493809 complement(4521801..4522361) 1 NC_008563.1 zinc resistance protein 4522361 zraP 4493809 zraP Escherichia coli APEC O1 zinc resistance protein YP_859587.1 4521801 R 405955 CDS YP_859588.1 117626265 4493810 4522458..4523834 1 NC_008563.1 sensor protein ZraS 4523834 zraS 4493810 zraS Escherichia coli APEC O1 sensor protein ZraS YP_859588.1 4522458 D 405955 CDS YP_859589.1 117626266 4493811 4523831..4525156 1 NC_008563.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4525156 zraR 4493811 zraR Escherichia coli APEC O1 transcriptional regulatory protein ZraR YP_859589.1 4523831 D 405955 CDS YP_859590.1 117626267 4492855 complement(4525153..4526442) 1 NC_008563.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4526442 purD 4492855 purD Escherichia coli APEC O1 phosphoribosylamine--glycine ligase YP_859590.1 4525153 R 405955 CDS YP_859591.1 117626268 4492856 complement(4526454..4528043) 1 NC_008563.1 purine biosynthesis; involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4528043 purH 4492856 purH Escherichia coli APEC O1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_859591.1 4526454 R 405955 CDS YP_859592.1 117626269 4492857 complement(4528359..4528619) 1 NC_008563.1 hypothetical protein 4528619 4492857 APECO1_2468 Escherichia coli APEC O1 hypothetical protein YP_859592.1 4528359 R 405955 CDS YP_859595.1 117626272 4492860 4533761..4534144 1 NC_008563.1 hypothetical protein 4534144 yjaA 4492860 yjaA Escherichia coli APEC O1 hypothetical protein YP_859595.1 4533761 D 405955 CDS YP_859596.1 117626273 4492861 complement(4534208..4534651) 1 NC_008563.1 acetyltransferase (GNAT) family; hypothetical protein 4534651 yjaB 4492861 yjaB Escherichia coli APEC O1 hypothetical protein YP_859596.1 4534208 R 405955 CDS YP_859597.1 117626274 4492862 4534808..4535737 1 NC_008563.1 acyltransferase activity; catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4535737 metA 4492862 metA Escherichia coli APEC O1 homoserine O-succinyltransferase YP_859597.1 4534808 D 405955 CDS YP_859598.1 117626275 4492863 4535988..4537607 1 NC_008563.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4537607 aceB 4492863 aceB Escherichia coli APEC O1 malate synthase YP_859598.1 4535988 D 405955 CDS YP_859599.1 117626276 4492864 4537622..4538941 1 NC_008563.1 isocitrate lyase 4538941 aceA 4492864 aceA Escherichia coli APEC O1 isocitrate lyase YP_859599.1 4537622 D 405955 CDS YP_859600.1 117626277 4492865 4538990..4540714 1 NC_008563.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4540714 aceK 4492865 aceK Escherichia coli APEC O1 bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_859600.1 4538990 D 405955 CDS YP_859601.1 117626278 4492866 complement(4540731..4541594) 1 NC_008563.1 bacterial regulatory protein; regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4541594 iclR 4492866 iclR Escherichia coli APEC O1 IclR family transcriptional regulator YP_859601.1 4540731 R 405955 CDS YP_859602.1 117626279 4492867 4541740..4545438 1 NC_008563.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4545438 metH 4492867 metH Escherichia coli APEC O1 B12-dependent methionine synthase YP_859602.1 4541740 D 405955 CDS YP_859603.1 117626280 4492868 4545498..4545818 1 NC_008563.1 hypothetical protein 4545818 4492868 APECO1_2457 Escherichia coli APEC O1 hypothetical protein YP_859603.1 4545498 D 405955 CDS YP_859604.1 117626281 4492869 4545861..4546310 1 NC_008563.1 hypothetical protein 4546310 4492869 APECO1_2456 Escherichia coli APEC O1 hypothetical protein YP_859604.1 4545861 D 405955 CDS YP_859605.1 117626282 4492870 4546481..4548112 1 NC_008563.1 hypothetical protein 4548112 yjbB 4492870 yjbB Escherichia coli APEC O1 hypothetical protein YP_859605.1 4546481 D 405955 CDS YP_859606.1 117626283 4492871 complement(4548202..4548891) 1 NC_008563.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4548891 pepE 4492871 pepE Escherichia coli APEC O1 peptidase E YP_859606.1 4548202 R 405955 CDS YP_859607.1 117626284 4492872 complement(4549273..4550514) 1 NC_008563.1 L-sorbose-1-P-reductase 4550514 4492872 APECO1_2453 Escherichia coli APEC O1 L-sorbose-1-P-reductase YP_859607.1 4549273 R 405955 CDS YP_859608.1 117626285 4492873 complement(4550554..4551396) 1 NC_008563.1 PTS system mannose-specific transporter subunit IID 4551396 4492873 APECO1_2452 Escherichia coli APEC O1 PTS system mannose-specific transporter subunit IID YP_859608.1 4550554 R 405955 CDS YP_859609.1 117626286 4493985 complement(4551389..4552186) 1 NC_008563.1 sorbose-permease PTS system IIC component SorA 4552186 sorA 4493985 sorA Escherichia coli APEC O1 sorbose-permease PTS system IIC component SorA YP_859609.1 4551389 R 405955 CDS YP_859610.1 117626287 4493986 complement(4552252..4552746) 1 NC_008563.1 PTS system, sorbose-specific IIB component 4552746 4493986 APECO1_2450 Escherichia coli APEC O1 PTS system, sorbose-specific IIB component YP_859610.1 4552252 R 405955 CDS YP_859611.1 117626288 4493987 complement(4552746..4553153) 1 NC_008563.1 sorbose PTS component 4553153 4493987 APECO1_2449 Escherichia coli APEC O1 sorbose PTS component YP_859611.1 4552746 R 405955 CDS YP_859612.1 117626289 4493988 complement(4553163..4553969) 1 NC_008563.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 4553969 4493988 APECO1_2448 Escherichia coli APEC O1 sorbitol-6-phosphate 2-dehydrogenase YP_859612.1 4553163 R 405955 CDS YP_859613.1 117626290 4493989 complement(4554039..4555031) 1 NC_008563.1 transcriptional regulator of sorbose uptake and utilization genes 4555031 4493989 APECO1_2447 Escherichia coli APEC O1 transcriptional regulator of sorbose uptake and utilization genes YP_859613.1 4554039 R 405955 CDS YP_859614.1 117626291 4493990 4555334..4556206 1 NC_008563.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4556206 yjbC 4493990 yjbC Escherichia coli APEC O1 23S rRNA pseudouridine synthase F YP_859614.1 4555334 D 405955 CDS YP_859615.1 117626292 4493991 complement(4556207..4556479) 1 NC_008563.1 hypothetical protein 4556479 yjbD 4493991 yjbD Escherichia coli APEC O1 hypothetical protein YP_859615.1 4556207 R 405955 CDS YP_859616.1 117626293 4493992 complement(4556732..4558081) 1 NC_008563.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4558081 lysC 4493992 lysC Escherichia coli APEC O1 aspartate kinase III YP_859616.1 4556732 R 405955 CDS YP_859617.1 117626294 4493993 4558606..4560255 1 NC_008563.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4560255 pgi 4493993 pgi Escherichia coli APEC O1 glucose-6-phosphate isomerase YP_859617.1 4558606 D 405955 CDS YP_859619.1 117626296 4493995 4561080..4561748 1 NC_008563.1 hypothetical protein 4561748 yjbF 4493995 yjbF Escherichia coli APEC O1 hypothetical protein YP_859619.1 4561080 D 405955 CDS YP_859620.1 117626297 4493996 4561745..4562482 1 NC_008563.1 hypothetical protein 4562482 yjbG 4493996 yjbG Escherichia coli APEC O1 hypothetical protein YP_859620.1 4561745 D 405955 CDS YP_859621.1 117626298 4493997 4562482..4564578 1 NC_008563.1 hypothetical protein 4564578 yjbH 4493997 yjbH Escherichia coli APEC O1 hypothetical protein YP_859621.1 4562482 D 405955 CDS YP_859622.1 117626299 4493998 complement(4564625..4564903) 1 NC_008563.1 hypothetical protein 4564903 4493998 APECO1_2438 Escherichia coli APEC O1 hypothetical protein YP_859622.1 4564625 R 405955 CDS YP_859623.1 117626300 4493999 4565118..4565528 1 NC_008563.1 phosphate-starvation-inducible protein PsiE 4565528 yjbE 4493999 yjbE Escherichia coli APEC O1 phosphate-starvation-inducible protein PsiE YP_859623.1 4565118 D 405955 CDS YP_859624.1 117626301 4494000 complement(4565622..4566512) 1 NC_008563.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4566512 malG 4494000 malG Escherichia coli APEC O1 maltose transporter permease YP_859624.1 4565622 R 405955 CDS YP_859625.1 117626302 4494001 complement(4566527..4568086) 1 NC_008563.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4568086 malF 4494001 malF Escherichia coli APEC O1 maltose transporter membrane protein YP_859625.1 4566527 R 405955 CDS YP_859626.1 117626303 4494002 complement(4568225..4569415) 1 NC_008563.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4569415 malE 4494002 malE Escherichia coli APEC O1 maltose ABC transporter periplasmic protein YP_859626.1 4568225 R 405955 CDS YP_859627.1 117626304 4494003 4569690..4570895 1 NC_008563.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4570895 malK 4494003 malK Escherichia coli APEC O1 maltose/maltodextrin transporter ATP-binding protein YP_859627.1 4569690 D 405955 CDS YP_859628.1 117626305 4494004 4570967..4572307 1 NC_008563.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4572307 lamB 4494004 lamB Escherichia coli APEC O1 maltoporin YP_859628.1 4570967 D 405955 CDS YP_859629.1 117626306 4493029 4572621..4573550 1 NC_008563.1 maltose regulon periplasmic protein 4573550 malM 4493029 malM Escherichia coli APEC O1 maltose regulon periplasmic protein YP_859629.1 4572621 D 405955 CDS YP_859630.1 117626307 4493030 4573729..4574226 1 NC_008563.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4574226 ubiC 4493030 ubiC Escherichia coli APEC O1 chorismate pyruvate lyase YP_859630.1 4573729 D 405955 CDS YP_859631.1 117626308 4493031 4574239..4575111 1 NC_008563.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4575111 ubiA 4493031 ubiA Escherichia coli APEC O1 4-hydroxybenzoate octaprenyltransferase YP_859631.1 4574239 D 405955 CDS YP_859632.1 117626309 4493032 complement(4575264..4577747) 1 NC_008563.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4577747 plsB 4493032 plsB Escherichia coli APEC O1 glycerol-3-phosphate acyltransferase YP_859632.1 4575264 R 405955 CDS YP_859633.1 117626310 4493033 4577858..4578226 1 NC_008563.1 diacylglycerol kinase DgkA 4578226 dgkA 4493033 dgkA Escherichia coli APEC O1 diacylglycerol kinase DgkA YP_859633.1 4577858 D 405955 CDS YP_859634.1 117626311 4493034 4578336..4578944 1 NC_008563.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4578944 lexA 4493034 lexA Escherichia coli APEC O1 LexA repressor YP_859634.1 4578336 D 405955 CDS YP_859635.1 117626312 4493035 4578963..4580342 1 NC_008563.1 DNA-damage-inducible SOS response protein 4580342 dinF 4493035 dinF Escherichia coli APEC O1 DNA-damage-inducible SOS response protein YP_859635.1 4578963 D 405955 CDS YP_859636.1 117626313 4493036 complement(4580709..4581395) 1 NC_008563.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4581395 yjbK 4493036 yjbK Escherichia coli APEC O1 zinc uptake transcriptional repressor YP_859636.1 4580709 R 405955 CDS YP_859637.1 117626314 4493037 4581380..4582375 1 NC_008563.1 tRNA-dihydrouridine synthase A 4582375 yjbN 4493037 yjbN Escherichia coli APEC O1 tRNA-dihydrouridine synthase A YP_859637.1 4581380 D 405955 CDS YP_859638.1 117626315 4493038 4582299..4582751 1 NC_008563.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4582751 pspG 4493038 pspG Escherichia coli APEC O1 phage shock protein G YP_859638.1 4582299 D 405955 CDS YP_859639.1 117626316 4493039 complement(4582916..4583899) 1 NC_008563.1 quinone oxidoreductase 4583899 qor 4493039 qor Escherichia coli APEC O1 quinone oxidoreductase YP_859639.1 4582916 R 405955 CDS YP_859640.1 117626317 4493040 complement(4584005..4586125) 1 NC_008563.1 oxidoreductase 4586125 4493040 APECO1_2420 Escherichia coli APEC O1 oxidoreductase YP_859640.1 4584005 R 405955 CDS YP_859641.1 117626318 4493041 complement(4586043..4587443) 1 NC_008563.1 transmembrane transport protein 4587443 4493041 APECO1_2419 Escherichia coli APEC O1 transmembrane transport protein YP_859641.1 4586043 R 405955 CDS YP_859642.1 117626319 4493042 complement(4587534..4588313) 1 NC_008563.1 enoyl-CoA hydratase/isomerase family protein 4588313 4493042 APECO1_2418 Escherichia coli APEC O1 enoyl-CoA hydratase/isomerase family protein YP_859642.1 4587534 R 405955 CDS YP_859643.1 117626320 4493043 complement(4588306..4589877) 1 NC_008563.1 propionate CoA-transferase 4589877 4493043 APECO1_2417 Escherichia coli APEC O1 propionate CoA-transferase YP_859643.1 4588306 R 405955 CDS YP_859644.1 117626321 4493044 4590133..4591167 1 NC_008563.1 LacI family transcriptional regulator 4591167 4493044 APECO1_2416 Escherichia coli APEC O1 LacI family transcriptional regulator YP_859644.1 4590133 D 405955 CDS YP_859645.1 117626322 4493045 4591240..4592655 1 NC_008563.1 unwinds double stranded DNA; replicative DNA helicase 4592655 dnaB 4493045 dnaB Escherichia coli APEC O1 replicative DNA helicase YP_859645.1 4591240 D 405955 CDS YP_859646.1 117626323 4493046 4592708..4593787 1 NC_008563.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4593787 alr 4493046 alr Escherichia coli APEC O1 alanine racemase YP_859646.1 4592708 D 405955 CDS YP_859647.1 117626324 4493047 4593810..4594367 1 NC_008563.1 transporter 4594367 4493047 APECO1_2413 Escherichia coli APEC O1 transporter YP_859647.1 4593810 D 405955 CDS YP_859648.1 117626325 4492658 4594340..4595362 1 NC_008563.1 NadR transcriptional repressor / NMN adenylyltransferase 4595362 4492658 APECO1_2412 Escherichia coli APEC O1 NadR transcriptional repressor / NMN adenylyltransferase YP_859648.1 4594340 D 405955 CDS YP_859649.1 117626326 4492659 4595444..4596637 1 NC_008563.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4596637 tyrB 4492659 tyrB Escherichia coli APEC O1 aromatic amino acid aminotransferase YP_859649.1 4595444 D 405955 CDS YP_859650.1 117626327 4492660 4596819..4599563 1 NC_008563.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 4599563 sucA 4492660 sucA Escherichia coli APEC O1 2-oxoglutarate dehydrogenase E1 component YP_859650.1 4596819 D 405955 CDS YP_859651.1 117626328 4492661 4599596..4600750 1 NC_008563.1 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 4600750 4492661 APECO1_2409 Escherichia coli APEC O1 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex YP_859651.1 4599596 D 405955 CDS YP_859652.1 117626329 4492662 4600762..4602180 1 NC_008563.1 subunit of 2-oxoglutarate dehydrogenase 4602180 4492662 APECO1_2408 Escherichia coli APEC O1 subunit of 2-oxoglutarate dehydrogenase YP_859652.1 4600762 D 405955 CDS YP_859653.1 117626330 4492663 4602202..4603371 1 NC_008563.1 SucC, succinyl-CoA synthetase beta chain 4603371 sucC 4492663 sucC Escherichia coli APEC O1 SucC, succinyl-CoA synthetase beta chain YP_859653.1 4602202 D 405955 CDS YP_859654.1 117626331 4492664 4603384..4604256 1 NC_008563.1 succinyl-CoA synthetase subunit alpha 4604256 4492664 APECO1_2406 Escherichia coli APEC O1 succinyl-CoA synthetase subunit alpha YP_859654.1 4603384 D 405955 CDS YP_859655.1 117626332 4492665 4604462..4605967 1 NC_008563.1 membrane-bound protein 4605967 4492665 APECO1_2405 Escherichia coli APEC O1 membrane-bound protein YP_859655.1 4604462 D 405955 CDS YP_859656.1 117626333 4492666 4605841..4607052 1 NC_008563.1 lactate dehydrogenase 4607052 4492666 APECO1_2404 Escherichia coli APEC O1 lactate dehydrogenase YP_859656.1 4605841 D 405955 CDS YP_859657.1 117626334 4492667 complement(4607041..4608399) 1 NC_008563.1 two component response regulator 4608399 4492667 APECO1_2403 Escherichia coli APEC O1 two component response regulator YP_859657.1 4607041 R 405955 CDS YP_859658.1 117626335 4492668 complement(4608392..4610212) 1 NC_008563.1 transport sensor protein 4610212 4492668 APECO1_2402 Escherichia coli APEC O1 transport sensor protein YP_859658.1 4608392 R 405955 CDS YP_859659.1 117626336 4492669 4610420..4611202 1 NC_008563.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4611202 aphA 4492669 aphA Escherichia coli APEC O1 acid phosphatase/phosphotransferase YP_859659.1 4610420 D 405955 CDS YP_859660.1 117626337 4492670 4611313..4611729 1 NC_008563.1 hypothetical protein 4611729 yjbQ 4492670 yjbQ Escherichia coli APEC O1 hypothetical protein YP_859660.1 4611313 D 405955 CDS YP_859661.1 117626338 4492671 4611733..4612089 1 NC_008563.1 hypothetical protein 4612089 yjbR 4492671 yjbR Escherichia coli APEC O1 hypothetical protein YP_859661.1 4611733 D 405955 CDS YP_859662.1 117626339 4492672 complement(4612124..4614946) 1 NC_008563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4614946 uvrA 4492672 uvrA Escherichia coli APEC O1 excinuclease ABC subunit A YP_859662.1 4612124 R 405955 CDS YP_859663.2 162317560 4492673 4615200..4615736 1 NC_008563.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4615736 ssb 4492673 ssb Escherichia coli APEC O1 single-stranded DNA-binding protein YP_859663.2 4615200 D 405955 CDS YP_859664.1 117626341 4492674 complement(4615835..4616185) 1 NC_008563.1 hypothetical protein 4616185 yjcB 4492674 yjcB Escherichia coli APEC O1 hypothetical protein YP_859664.1 4615835 R 405955 CDS YP_859665.1 117626342 4492675 4616545..4618131 1 NC_008563.1 signal transduction protein YjcC 4618131 yjcC 4492675 yjcC Escherichia coli APEC O1 signal transduction protein YjcC YP_859665.1 4616545 D 405955 CDS YP_859666.1 117626343 4492676 4618543..4619007 1 NC_008563.1 redox-sensitive transcriptional activator SoxR 4619007 soxR 4492676 soxR Escherichia coli APEC O1 redox-sensitive transcriptional activator SoxR YP_859666.1 4618543 D 405955 CDS YP_859667.1 117626344 4492677 4619554..4620903 1 NC_008563.1 xanthine/uracil permeases family protein YjcD 4620903 yjcD 4492677 yjcD Escherichia coli APEC O1 xanthine/uracil permeases family protein YjcD YP_859667.1 4619554 D 405955 CDS YP_859668.1 117626345 4493379 4621054..4622703 1 NC_008563.1 sodium/hydrogen exchanger family protein YjcE 4622703 yjcE 4493379 yjcE Escherichia coli APEC O1 sodium/hydrogen exchanger family protein YjcE YP_859668.1 4621054 D 405955 CDS YP_859669.1 117626346 4493380 complement(4622739..4623623) 1 NC_008563.1 LysR family transcriptional regulator 4623623 4493380 APECO1_2391 Escherichia coli APEC O1 LysR family transcriptional regulator YP_859669.1 4622739 R 405955 CDS YP_859670.1 117626347 4493381 4623727..4624137 1 NC_008563.1 murein hydrolase exporter 4624137 4493381 APECO1_2390 Escherichia coli APEC O1 murein hydrolase exporter YP_859670.1 4623727 D 405955 CDS YP_859671.1 117626348 4493382 4624130..4624819 1 NC_008563.1 LrgB family murein hydrolase regulator 4624819 4493382 APECO1_2389 Escherichia coli APEC O1 LrgB family murein hydrolase regulator YP_859671.1 4624130 D 405955 CDS YP_859672.1 117626349 4493383 complement(4624858..4626507) 1 NC_008563.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4626507 actP 4493383 actP Escherichia coli APEC O1 acetate permease YP_859672.1 4624858 R 405955 CDS YP_859673.1 117626350 4493384 complement(4626504..4626821) 1 NC_008563.1 hypothetical protein 4626821 yjcH 4493384 yjcH Escherichia coli APEC O1 hypothetical protein YP_859673.1 4626504 R 405955 CDS YP_859674.1 117626351 4493385 complement(4627110..4629068) 1 NC_008563.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4629068 acs 4493385 acs Escherichia coli APEC O1 acetyl-CoA synthetase YP_859674.1 4627110 R 405955 CDS YP_859675.1 117626352 4493386 4629460..4630896 1 NC_008563.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4630896 nrfA 4493386 nrfA Escherichia coli APEC O1 cytochrome c552 YP_859675.1 4629460 D 405955 CDS YP_859676.1 117626353 4493387 4630935..4631507 1 NC_008563.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4631507 nrfB 4493387 nrfB Escherichia coli APEC O1 cytochrome c nitrite reductase pentaheme subunit YP_859676.1 4630935 D 405955 CDS YP_859677.1 117626354 4493388 4631504..4632175 1 NC_008563.1 formate-dependent nitire reductase subunit NrfC 4632175 nrfC 4493388 nrfC Escherichia coli APEC O1 formate-dependent nitire reductase subunit NrfC YP_859677.1 4631504 D 405955 CDS YP_859678.1 117626355 4493389 4632172..4633128 1 NC_008563.1 formate-dependent nitrite reductase, membrane subunit NrfD 4633128 nrfD 4493389 nrfD Escherichia coli APEC O1 formate-dependent nitrite reductase, membrane subunit NrfD YP_859678.1 4632172 D 405955 CDS YP_859679.1 117626356 4493390 4633208..4634866 1 NC_008563.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4634866 nrfE 4493390 nrfE Escherichia coli APEC O1 heme lyase subunit NrfE YP_859679.1 4633208 D 405955 CDS YP_859680.1 117626357 4493391 4635173..4635835 1 NC_008563.1 formate-dependent nitrite reductase complex subunit NrfG 4635835 nrfG 4493391 nrfG Escherichia coli APEC O1 formate-dependent nitrite reductase complex subunit NrfG YP_859680.1 4635173 D 405955 CDS YP_859681.1 117626358 4493392 4636178..4637491 1 NC_008563.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4637491 gltP 4493392 gltP Escherichia coli APEC O1 glutamate/aspartate:proton symporter YP_859681.1 4636178 D 405955 CDS YP_859682.1 117626359 4493393 complement(4637639..4638328) 1 NC_008563.1 hypothetical protein 4638328 yjcO 4493393 yjcO Escherichia coli APEC O1 hypothetical protein YP_859682.1 4637639 R 405955 CDS YP_859683.1 117626360 4493394 complement(4638439..4639143) 1 NC_008563.1 ABC transporter ATP-binding protein 4639143 yddO 4493394 yddO Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_859683.1 4638439 R 405955 CDS YP_859684.1 117626361 4493395 complement(4639130..4639999) 1 NC_008563.1 ABC transporter transporter ATP-binding protein 4639999 yddP 4493395 yddP Escherichia coli APEC O1 ABC transporter transporter ATP-binding protein YP_859684.1 4639130 R 405955 CDS YP_859685.1 117626362 4493396 complement(4639959..4640792) 1 NC_008563.1 ABC transporter permease 4640792 yddQ 4493396 yddQ Escherichia coli APEC O1 ABC transporter permease YP_859685.1 4639959 R 405955 CDS YP_859686.1 117626363 4493397 complement(4640792..4641934) 1 NC_008563.1 ABC transporter permease 4641934 yddR 4493397 yddR Escherichia coli APEC O1 ABC transporter permease YP_859686.1 4640792 R 405955 CDS YP_859687.1 117626364 4493106 complement(4641941..4643509) 1 NC_008563.1 ABC transporter periplasmic oligo-dipeptide/nickel binding protein 4643509 4493106 APECO1_2373 Escherichia coli APEC O1 ABC transporter periplasmic oligo-dipeptide/nickel binding protein YP_859687.1 4641941 R 405955 CDS YP_859688.1 117626365 4493107 complement(4643884..4645563) 1 NC_008563.1 authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-H, selenopolypeptide subunit 4645563 fdhF 4493107 fdhF Escherichia coli APEC O1 formate dehydrogenase-H, selenopolypeptide subunit YP_859688.1 4643884 R 405955 CDS YP_859689.1 117626366 4493108 complement(4645612..4646031) 1 NC_008563.1 authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-H, selenopolypeptide subunit 4646031 fdhF 4493108 fdhF Escherichia coli APEC O1 formate dehydrogenase-H, selenopolypeptide subunit YP_859689.1 4645612 R 405955 CDS YP_859690.1 117626367 4493109 complement(4646229..4647695) 1 NC_008563.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4647695 yjcP 4493109 yjcP Escherichia coli APEC O1 outer membrane efflux protein MdtP YP_859690.1 4646229 R 405955 CDS YP_859691.1 117626368 4493110 complement(4647692..4649743) 1 NC_008563.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4649743 yjcQ 4493110 yjcQ Escherichia coli APEC O1 multidrug efflux system protein MdtO YP_859691.1 4647692 R 405955 CDS YP_859692.1 117626369 4493111 complement(4649743..4650774) 1 NC_008563.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4650774 yjcR 4493111 yjcR Escherichia coli APEC O1 multidrug resistance protein MdtN YP_859692.1 4649743 R 405955 CDS YP_859693.1 117626370 4493112 complement(4650793..4651068) 1 NC_008563.1 hypothetical protein 4651068 4493112 APECO1_2368 Escherichia coli APEC O1 hypothetical protein YP_859693.1 4650793 R 405955 CDS YP_859694.1 117626371 4493113 complement(4651276..4653273) 1 NC_008563.1 hypothetical protein 4653273 yjcS 4493113 yjcS Escherichia coli APEC O1 hypothetical protein YP_859694.1 4651276 R 405955 CDS YP_859695.1 117626372 4493114 complement(4653536..4654465) 1 NC_008563.1 D-allose kinase 4654465 yjcT 4493114 yjcT Escherichia coli APEC O1 D-allose kinase YP_859695.1 4653536 R 405955 CDS YP_859696.1 117626373 4493115 complement(4654449..4655144) 1 NC_008563.1 allulose-6-phosphate 3-epimerase 4655144 yjcU 4493115 yjcU Escherichia coli APEC O1 allulose-6-phosphate 3-epimerase YP_859696.1 4654449 R 405955 CDS YP_859697.1 117626374 4493116 complement(4655155..4655862) 1 NC_008563.1 D-allose transport system permease protein AlsC 4655862 alsC 4493116 alsC Escherichia coli APEC O1 D-allose transport system permease protein AlsC YP_859697.1 4655155 R 405955 CDS YP_859698.1 117626375 4493117 complement(4656114..4657646) 1 NC_008563.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4657646 alsA 4493117 alsA Escherichia coli APEC O1 D-allose transporter ATP-binding protein YP_859698.1 4656114 R 405955 CDS YP_859699.1 117626376 4493118 complement(4657773..4658714) 1 NC_008563.1 D-allose transporter subunit 4658714 4493118 APECO1_2362 Escherichia coli APEC O1 D-allose transporter subunit YP_859699.1 4657773 R 405955 CDS YP_859700.1 117626377 4493119 complement(4658767..4659690) 1 NC_008563.1 involved in rpiB and als operon repression; RpiR family transcriptional regulator 4659690 rpiR 4493119 rpiR Escherichia coli APEC O1 RpiR family transcriptional regulator YP_859700.1 4658767 R 405955 CDS YP_859701.1 117626378 4493120 4660016..4660465 1 NC_008563.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4660465 rpiB 4493120 rpiB Escherichia coli APEC O1 ribose-5-phosphate isomerase B YP_859701.1 4660016 D 405955 CDS YP_859702.1 117626379 4493121 4660534..4660863 1 NC_008563.1 hypothetical protein 4660863 4493121 APECO1_2359 Escherichia coli APEC O1 hypothetical protein YP_859702.1 4660534 D 405955 CDS YP_859703.1 117626380 4493122 complement(4660891..4661649) 1 NC_008563.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4661649 phnP 4493122 phnP Escherichia coli APEC O1 carbon-phosphorus lyase complex accessory protein YP_859703.1 4660891 R 405955 CDS YP_859704.1 117626381 4493123 complement(4661651..4662085) 1 NC_008563.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4662085 phnO 4493123 phnO Escherichia coli APEC O1 aminoalkylphosphonic acid N-acetyltransferase YP_859704.1 4661651 R 405955 CDS YP_859705.1 117626382 4493124 complement(4662072..4662629) 1 NC_008563.1 ribose 1,5-bisphosphokinase 4662629 phnN 4493124 phnN Escherichia coli APEC O1 ribose 1,5-bisphosphokinase YP_859705.1 4662072 R 405955 CDS YP_859706.1 117626383 4493125 complement(4662629..4663765) 1 NC_008563.1 carbon-phosphorus lyase complex subunit PhnM 4663765 phnM 4493125 phnM Escherichia coli APEC O1 carbon-phosphorus lyase complex subunit PhnM YP_859706.1 4662629 R 405955 CDS YP_859707.1 117626384 4492894 complement(4663762..4664541) 1 NC_008563.1 phosphonates transport ATP-binding protein PhnL 4664541 phnL 4492894 phnL Escherichia coli APEC O1 phosphonates transport ATP-binding protein PhnL YP_859707.1 4663762 R 405955 CDS YP_859708.1 117626385 4492895 complement(4664553..4665311) 1 NC_008563.1 phosphonate C-P lyase system protein PhnK 4665311 phnK 4492895 phnK Escherichia coli APEC O1 phosphonate C-P lyase system protein PhnK YP_859708.1 4664553 R 405955 CDS YP_859709.1 117626386 4492896 4665410..4666081 1 NC_008563.1 carbon-phosphorus lyase complex subunit PhnJ 4666081 phnJ 4492896 phnJ Escherichia coli APEC O1 carbon-phosphorus lyase complex subunit PhnJ YP_859709.1 4665410 D 405955 CDS YP_859710.1 117626387 4492897 complement(4666146..4667216) 1 NC_008563.1 carbon-phosphorus lyase complex subunit PhnI 4667216 phnI 4492897 phnI Escherichia coli APEC O1 carbon-phosphorus lyase complex subunit PhnI YP_859710.1 4666146 R 405955 CDS YP_859711.1 117626388 4492898 complement(4667210..4667794) 1 NC_008563.1 carbon-phosphorus lyase complex subunit 4667794 phnH 4492898 phnH Escherichia coli APEC O1 carbon-phosphorus lyase complex subunit YP_859711.1 4667210 R 405955 CDS YP_859712.1 117626389 4492899 complement(4667791..4668243) 1 NC_008563.1 carbon-phosphorus lyase complex subunit PhnG 4668243 phnG 4492899 phnG Escherichia coli APEC O1 carbon-phosphorus lyase complex subunit PhnG YP_859712.1 4667791 R 405955 CDS YP_859713.1 117626390 4492900 complement(4668244..4668975) 1 NC_008563.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4668975 phnF 4492900 phnF Escherichia coli APEC O1 phosphonate metabolism transcriptional regulator PhnF YP_859713.1 4668244 R 405955 CDS YP_859714.1 117626391 4492901 complement(4668990..4669832) 1 NC_008563.1 alkylphosphonate ABC transporter subunit PhnE 4669832 phnE 4492901 phnE Escherichia coli APEC O1 alkylphosphonate ABC transporter subunit PhnE YP_859714.1 4668990 R 405955 CDS YP_859715.1 117626392 4492902 complement(4669875..4670891) 1 NC_008563.1 alkylphosphonate ABC transporter subunit PhnD 4670891 phnD 4492902 phnD Escherichia coli APEC O1 alkylphosphonate ABC transporter subunit PhnD YP_859715.1 4669875 R 405955 CDS YP_859716.1 117626393 4492903 complement(4670916..4671704) 1 NC_008563.1 phosphonate/organophosphate ester transporter subunit 4671704 phnC 4492903 phnC Escherichia coli APEC O1 phosphonate/organophosphate ester transporter subunit YP_859716.1 4670916 R 405955 CDS YP_859717.1 117626394 4492904 complement(4671837..4672280) 1 NC_008563.1 hypothetical protein 4672280 phnB 4492904 phnB Escherichia coli APEC O1 hypothetical protein YP_859717.1 4671837 R 405955 CDS YP_859718.1 117626395 4492905 4672335..4672769 1 NC_008563.1 hypothetical protein 4672769 4492905 APECO1_2343 Escherichia coli APEC O1 hypothetical protein YP_859718.1 4672335 D 405955 CDS YP_859719.1 117626396 4492906 4673178..4675406 1 NC_008563.1 hypothetical protein 4675406 yjdA 4492906 yjdA Escherichia coli APEC O1 hypothetical protein YP_859719.1 4673178 D 405955 CDS YP_859720.1 117626397 4492907 4675436..4676281 1 NC_008563.1 hypothetical protein 4676281 yjcZ 4492907 yjcZ Escherichia coli APEC O1 hypothetical protein YP_859720.1 4675436 D 405955 CDS YP_859721.1 117626398 4492908 4676545..4678047 1 NC_008563.1 proline/glycine betaine transporter 4678047 proP 4492908 proP Escherichia coli APEC O1 proline/glycine betaine transporter YP_859721.1 4676545 D 405955 CDS YP_859722.1 117626399 4492909 complement(4678224..4679315) 1 NC_008563.1 sensor protein BasS/PmrB 4679315 basS 4492909 basS Escherichia coli APEC O1 sensor protein BasS/PmrB YP_859722.1 4678224 R 405955 CDS YP_859723.1 117626400 4492910 complement(4679325..4679993) 1 NC_008563.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4679993 basR 4492910 basR Escherichia coli APEC O1 DNA-binding transcriptional regulator BasR YP_859723.1 4679325 R 405955 CDS YP_859724.1 117626401 4492911 complement(4679990..4681663) 1 NC_008563.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 4681663 yjdB 4492911 yjdB Escherichia coli APEC O1 cell division protein YP_859724.1 4679990 R 405955 CDS YP_859725.1 117626402 4492912 complement(4681737..4683074) 1 NC_008563.1 arginine:agmatin antiporter 4683074 yjdE 4492912 yjdE Escherichia coli APEC O1 arginine:agmatin antiporter YP_859725.1 4681737 R 405955 CDS YP_859726.1 117626403 4494565 complement(4683211..4683972) 1 NC_008563.1 regulatory protein AdiY 4683972 adiY 4494565 adiY Escherichia coli APEC O1 regulatory protein AdiY YP_859726.1 4683211 R 405955 CDS YP_859727.1 117626404 4494566 complement(4684308..4686578) 1 NC_008563.1 biodegradative arginine decarboxylase 4686578 adiA 4494566 adiA Escherichia coli APEC O1 biodegradative arginine decarboxylase YP_859727.1 4684308 R 405955 CDS YP_859728.1 117626405 4494567 complement(4686774..4687682) 1 NC_008563.1 DNA-binding transcriptional regulator MelR 4687682 melR 4494567 melR Escherichia coli APEC O1 DNA-binding transcriptional regulator MelR YP_859728.1 4686774 R 405955 CDS YP_859729.1 117626406 4494568 4687965..4689320 1 NC_008563.1 alpha-galactosidase 4689320 melA 4494568 melA Escherichia coli APEC O1 alpha-galactosidase YP_859729.1 4687965 D 405955 CDS YP_859730.1 117626407 4494569 complement(4689317..4689967) 1 NC_008563.1 hypothetical protein 4689967 yjdF 4494569 yjdF Escherichia coli APEC O1 hypothetical protein YP_859730.1 4689317 R 405955 CDS YP_859731.1 117626408 4494570 complement(4690090..4691736) 1 NC_008563.1 anaerobic class I fumarate hydratase 4691736 fumB 4494570 fumB Escherichia coli APEC O1 anaerobic class I fumarate hydratase YP_859731.1 4690090 R 405955 CDS YP_859732.1 117626409 4494571 complement(4691814..4693154) 1 NC_008563.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4693154 dcuB 4494571 dcuB Escherichia coli APEC O1 anaerobic C4-dicarboxylate transporter YP_859732.1 4691814 R 405955 CDS YP_859733.1 117626410 4494572 complement(4693725..4694444) 1 NC_008563.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DcuR family transcriptional regulator 4694444 yjdG 4494572 yjdG Escherichia coli APEC O1 DcuR family transcriptional regulator YP_859733.1 4693725 R 405955 CDS YP_859734.1 117626411 4494573 complement(4694441..4696072) 1 NC_008563.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4696072 yjdH 4494573 yjdH Escherichia coli APEC O1 sensory histidine kinase DcuS YP_859734.1 4694441 R 405955 CDS YP_859735.1 117626412 4494574 4696495..4696767 1 NC_008563.1 acyltransferase 4696767 yjdJ 4494574 yjdJ Escherichia coli APEC O1 acyltransferase YP_859735.1 4696495 D 405955 CDS YP_859736.1 117626413 4494575 4696995..4697291 1 NC_008563.1 hypothetical protein 4697291 yjdK 4494575 yjdK Escherichia coli APEC O1 hypothetical protein YP_859736.1 4696995 D 405955 CDS YP_859737.1 117626414 4494576 complement(4697611..4699128) 1 NC_008563.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4699128 lysS 4494576 lysS Escherichia coli APEC O1 lysyl-tRNA synthetase YP_859737.1 4697611 R 405955 CDS YP_859738.1 117626415 4494577 complement(4699365..4700822) 1 NC_008563.1 peptide transporter 4700822 yjdL 4494577 yjdL Escherichia coli APEC O1 peptide transporter YP_859738.1 4699365 R 405955 CDS YP_859739.1 117626416 4494578 complement(4700881..4703067) 1 NC_008563.1 lysine decarboxylase 1 4703067 cadA 4494578 cadA Escherichia coli APEC O1 lysine decarboxylase 1 YP_859739.1 4700881 R 405955 CDS YP_859740.1 117626417 4494579 complement(4703108..4704442) 1 NC_008563.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4704442 cadB 4494579 cadB Escherichia coli APEC O1 lysine/cadaverine antiporter YP_859740.1 4703108 R 405955 CDS YP_859741.1 117626418 4494580 complement(4704808..4706346) 1 NC_008563.1 regulates the cadBA operon; CadC family transcriptional regulator 4706346 cadC 4494580 cadC Escherichia coli APEC O1 CadC family transcriptional regulator YP_859741.1 4704808 R 405955 CDS YP_859742.1 117626419 4494581 complement(4707178..4707741) 1 NC_008563.1 hypothetical protein 4707741 4494581 APECO1_2319 Escherichia coli APEC O1 hypothetical protein YP_859742.1 4707178 R 405955 CDS YP_859743.1 117626420 4494582 complement(4707826..4708248) 1 NC_008563.1 hypothetical protein 4708248 4494582 APECO1_2318 Escherichia coli APEC O1 hypothetical protein YP_859743.1 4707826 R 405955 CDS YP_859744.1 117626421 4494583 4708543..4709076 1 NC_008563.1 hypothetical protein 4709076 4494583 APECO1_2317 Escherichia coli APEC O1 hypothetical protein YP_859744.1 4708543 D 405955 CDS YP_859745.1 117626422 4494584 complement(4709467..4709943) 1 NC_008563.1 radC-like protein YeeS 4709943 yeeS3 4494584 yeeS3 Escherichia coli APEC O1 radC-like protein YeeS YP_859745.1 4709467 R 405955 CDS YP_859746.1 117626423 4495030 4709994..4710401 1 NC_008563.1 hypothetical protein 4710401 4495030 APECO1_2315 Escherichia coli APEC O1 hypothetical protein YP_859746.1 4709994 D 405955 CDS YP_859747.1 117626424 4495031 complement(4710703..4711521) 1 NC_008563.1 hypothetical protein 4711521 4495031 APECO1_2314 Escherichia coli APEC O1 hypothetical protein YP_859747.1 4710703 R 405955 CDS YP_859748.1 117626425 4495032 complement(4711850..4712635) 1 NC_008563.1 hypothetical protein 4712635 4495032 APECO1_2313 Escherichia coli APEC O1 hypothetical protein YP_859748.1 4711850 R 405955 CDS YP_859749.1 117626426 4495033 complement(4712678..4713358) 1 NC_008563.1 transcriptional regulator 4713358 yfjR 4495033 yfjR Escherichia coli APEC O1 transcriptional regulator YP_859749.1 4712678 R 405955 CDS YP_859750.1 117626427 4495034 complement(4713561..4714445) 1 NC_008563.1 GTPase 4714445 4495034 APECO1_2311 Escherichia coli APEC O1 GTPase YP_859750.1 4713561 R 405955 CDS YP_859751.1 117626428 4495035 4714546..4715769 1 NC_008563.1 hypothetical protein 4715769 4495035 APECO1_2310 Escherichia coli APEC O1 hypothetical protein YP_859751.1 4714546 D 405955 CDS YP_859752.1 117626429 4495036 4717222..4717953 1 NC_008563.1 hypothetical protein 4717953 4495036 APECO1_2309 Escherichia coli APEC O1 hypothetical protein YP_859752.1 4717222 D 405955 CDS YP_859753.1 117626430 4495037 4718111..4718875 1 NC_008563.1 hypothetical protein 4718875 4495037 APECO1_2308 Escherichia coli APEC O1 hypothetical protein YP_859753.1 4718111 D 405955 CDS YP_859755.1 117626432 4495039 complement(4719452..4719787) 1 NC_008563.1 transposase InsC for insertion element IS2A/D/F/H/I/K 4719787 4495039 APECO1_2306 Escherichia coli APEC O1 transposase InsC for insertion element IS2A/D/F/H/I/K YP_859755.1 4719452 R 405955 CDS YP_859756.1 117626433 4495040 4719926..4720990 1 NC_008563.1 cation/multidrug efflux pump protein 4720990 4495040 APECO1_2305 Escherichia coli APEC O1 cation/multidrug efflux pump protein YP_859756.1 4719926 D 405955 CDS YP_859757.1 117626434 4495041 4721090..4721461 1 NC_008563.1 transcriptional repressor 4721461 4495041 APECO1_2304 Escherichia coli APEC O1 transcriptional repressor YP_859757.1 4721090 D 405955 CDS YP_859758.1 117626435 4495042 complement(4722436..4723077) 1 NC_008563.1 hypothetical protein 4723077 4495042 APECO1_2303 Escherichia coli APEC O1 hypothetical protein YP_859758.1 4722436 R 405955 CDS YP_859759.2 162317559 4495043 complement(4723026..4724177) 1 NC_008563.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 4724177 4495043 APECO1_2302 Escherichia coli APEC O1 S-adenosylmethionine synthetase YP_859759.2 4723026 R 405955 CDS YP_859760.1 117626437 4495044 complement(4724306..4725361) 1 NC_008563.1 hypothetical protein 4725361 4495044 APECO1_2301 Escherichia coli APEC O1 hypothetical protein YP_859760.1 4724306 R 405955 CDS YP_859761.1 117626438 4495045 complement(4725378..4726640) 1 NC_008563.1 histidine kinase 4726640 4495045 APECO1_2300 Escherichia coli APEC O1 histidine kinase YP_859761.1 4725378 R 405955 CDS YP_859762.1 117626439 4495046 4726675..4726986 1 NC_008563.1 hypothetical protein 4726986 4495046 APECO1_2299 Escherichia coli APEC O1 hypothetical protein YP_859762.1 4726675 D 405955 CDS YP_859763.1 117626440 4495047 complement(4727190..4727711) 1 NC_008563.1 reverse trasncriptase-like protein; hypothetical protein 4727711 4495047 APECO1_2298 Escherichia coli APEC O1 hypothetical protein YP_859763.1 4727190 R 405955 CDS YP_859764.1 117626441 4495048 complement(4727739..4728278) 1 NC_008563.1 reverse trasncriptase-like protein; hypothetical protein 4728278 4495048 APECO1_2297 Escherichia coli APEC O1 hypothetical protein YP_859764.1 4727739 R 405955 CDS YP_859765.1 117626442 4494251 4728503..4728790 1 NC_008563.1 hypothetical protein 4728790 4494251 APECO1_2296 Escherichia coli APEC O1 hypothetical protein YP_859765.1 4728503 D 405955 CDS YP_859766.1 117626443 4494252 complement(4728764..4729669) 1 NC_008563.1 hypothetical protein 4729669 4494252 APECO1_2295 Escherichia coli APEC O1 hypothetical protein YP_859766.1 4728764 R 405955 CDS YP_859767.1 117626444 4494253 complement(4729806..4730723) 1 NC_008563.1 pyruvate-formate lyase-activating enzyme 4730723 4494253 APECO1_2294 Escherichia coli APEC O1 pyruvate-formate lyase-activating enzyme YP_859767.1 4729806 R 405955 CDS YP_859768.1 117626445 4494254 complement(4730832..4733384) 1 NC_008563.1 pyruvate formate-lyase 4733384 4494254 APECO1_2293 Escherichia coli APEC O1 pyruvate formate-lyase YP_859768.1 4730832 R 405955 CDS YP_859769.1 117626446 4494255 complement(4733433..4734143) 1 NC_008563.1 peptidase 4734143 4494255 APECO1_2292 Escherichia coli APEC O1 peptidase YP_859769.1 4733433 R 405955 CDS YP_859770.1 117626447 4494256 complement(4734342..4735868) 1 NC_008563.1 ethanolamine utilization protein EutE 4735868 eutE 4494256 eutE Escherichia coli APEC O1 ethanolamine utilization protein EutE YP_859770.1 4734342 R 405955 CDS YP_859771.1 117626448 4494257 complement(4735929..4736714) 1 NC_008563.1 propanediol utilization protein 4736714 eutL 4494257 eutL Escherichia coli APEC O1 propanediol utilization protein YP_859771.1 4735929 R 405955 CDS YP_859772.1 117626449 4494258 complement(4736736..4737017) 1 NC_008563.1 propanediol utilization protein PduA 4737017 pduA 4494258 pduA Escherichia coli APEC O1 propanediol utilization protein PduA YP_859772.1 4736736 R 405955 CDS YP_859773.1 117626450 4494259 complement(4737302..4738609) 1 NC_008563.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 4738609 4494259 APECO1_2288 Escherichia coli APEC O1 propionate/acetate kinase YP_859773.1 4737302 R 405955 CDS YP_859774.1 117626451 4494260 complement(4738527..4739024) 1 NC_008563.1 propanediol utilization protein 4739024 pduO 4494260 pduO Escherichia coli APEC O1 propanediol utilization protein YP_859774.1 4738527 R 405955 CDS YP_859775.1 117626452 4494261 complement(4739052..4739321) 1 NC_008563.1 ethanolamine utilization protein EutN 4739321 eutN 4494261 eutN Escherichia coli APEC O1 ethanolamine utilization protein EutN YP_859775.1 4739052 R 405955 CDS YP_859776.1 117626453 4494262 complement(4739333..4740058) 1 NC_008563.1 hypothetical protein 4740058 4494262 APECO1_2285 Escherichia coli APEC O1 hypothetical protein YP_859776.1 4739333 R 405955 CDS YP_859777.1 117626454 4494263 complement(4740042..4740800) 1 NC_008563.1 ethanolamine utilization protein EutJ 4740800 eutJ 4494263 eutJ Escherichia coli APEC O1 ethanolamine utilization protein EutJ YP_859777.1 4740042 R 405955 CDS YP_859778.1 117626455 4494264 complement(4740855..4741541) 1 NC_008563.1 propanediol utilization protein 4741541 4494264 APECO1_2283 Escherichia coli APEC O1 propanediol utilization protein YP_859778.1 4740855 R 405955 CDS YP_859779.1 117626456 4494265 complement(4741681..4742799) 1 NC_008563.1 iron-containing alcohol dehydrogenase 4742799 4494265 APECO1_2282 Escherichia coli APEC O1 iron-containing alcohol dehydrogenase YP_859779.1 4741681 R 405955 CDS YP_859780.1 117626457 4494266 complement(4743291..4743695) 1 NC_008563.1 hypothetical protein 4743695 4494266 APECO1_2281 Escherichia coli APEC O1 hypothetical protein YP_859780.1 4743291 R 405955 CDS YP_859781.1 117626458 4494267 4743929..4744204 1 NC_008563.1 hypothetical protein 4744204 4494267 APECO1_2280 Escherichia coli APEC O1 hypothetical protein YP_859781.1 4743929 D 405955 CDS YP_859782.1 117626459 4494268 4744842..4745252 1 NC_008563.1 hemolysin activator protein 4745252 4494268 APECO1_2279 Escherichia coli APEC O1 hemolysin activator protein YP_859782.1 4744842 D 405955 CDS YP_859783.1 117626460 4494269 4745339..4745722 1 NC_008563.1 hypothetical protein 4745722 4494269 APECO1_2278 Escherichia coli APEC O1 hypothetical protein YP_859783.1 4745339 D 405955 CDS YP_859784.1 117626461 4494270 4745961..4747415 1 NC_008563.1 hypothetical protein 4747415 4494270 APECO1_2277 Escherichia coli APEC O1 hypothetical protein YP_859784.1 4745961 D 405955 CDS YP_859785.1 117626462 4492971 4747547..4749331 1 NC_008563.1 KAP family protein 4749331 4492971 APECO1_2276 Escherichia coli APEC O1 KAP family protein YP_859785.1 4747547 D 405955 CDS YP_859786.1 117626463 4492972 4749331..4750083 1 NC_008563.1 hypothetical protein 4750083 4492972 APECO1_2275 Escherichia coli APEC O1 hypothetical protein YP_859786.1 4749331 D 405955 CDS YP_859787.1 117626464 4492973 4750065..4751384 1 NC_008563.1 hypothetical protein 4751384 4492973 APECO1_2274 Escherichia coli APEC O1 hypothetical protein YP_859787.1 4750065 D 405955 CDS YP_859788.1 117626465 4492974 4751381..4752106 1 NC_008563.1 TatD-related deoxyribonuclease 4752106 4492974 APECO1_2273 Escherichia coli APEC O1 TatD-related deoxyribonuclease YP_859788.1 4751381 D 405955 CDS YP_859789.1 117626466 4492975 complement(4752659..4753234) 1 NC_008563.1 hypothetical protein 4753234 4492975 APECO1_2272 Escherichia coli APEC O1 hypothetical protein YP_859789.1 4752659 R 405955 CDS YP_859790.1 117626467 4492976 complement(4753242..4754570) 1 NC_008563.1 hypothetical protein 4754570 4492976 APECO1_2271 Escherichia coli APEC O1 hypothetical protein YP_859790.1 4753242 R 405955 CDS YP_859791.1 117626468 4492977 complement(4754911..4755723) 1 NC_008563.1 transposase insF for insertion sequence IS3A/B/C/D/E/fA 4755723 4492977 APECO1_2270 Escherichia coli APEC O1 transposase insF for insertion sequence IS3A/B/C/D/E/fA YP_859791.1 4754911 R 405955 CDS YP_859792.1 117626469 4492978 complement(4755780..4756103) 1 NC_008563.1 transposase InsN for insertion sequence element IS911B 4756103 insN 4492978 insN Escherichia coli APEC O1 transposase InsN for insertion sequence element IS911B YP_859792.1 4755780 R 405955 CDS YP_859793.1 117626470 4492979 complement(4756137..4756514) 1 NC_008563.1 hypothetical protein 4756514 4492979 APECO1_2268 Escherichia coli APEC O1 hypothetical protein YP_859793.1 4756137 R 405955 CDS YP_859794.1 117626471 4492980 complement(4757137..4757496) 1 NC_008563.1 iso-InsB; IS1 InsB protein 4757496 insB 4492980 insB Escherichia coli APEC O1 IS1 InsB protein YP_859794.1 4757137 R 405955 CDS YP_859795.1 117626472 4492981 complement(4757523..4757795) 1 NC_008563.1 iso-InsA; IS1 InsA protein 4757795 insA 4492981 insA Escherichia coli APEC O1 IS1 InsA protein YP_859795.1 4757523 R 405955 CDS YP_859796.1 117626473 4492982 4758048..4759517 1 NC_008563.1 antiporter 4759517 4492982 APECO1_2265 Escherichia coli APEC O1 antiporter YP_859796.1 4758048 D 405955 CDS YP_859797.1 117626474 4492983 4759622..4761991 1 NC_008563.1 hypothetical protein 4761991 4492983 APECO1_2264 Escherichia coli APEC O1 hypothetical protein YP_859797.1 4759622 D 405955 CDS YP_859798.1 117626475 4492984 4762066..4763565 1 NC_008563.1 amino acid antiporter 4763565 4492984 APECO1_2263 Escherichia coli APEC O1 amino acid antiporter YP_859798.1 4762066 D 405955 CDS YP_859799.1 117626476 4492985 4763708..4763983 1 NC_008563.1 IS1 InsA protein 4763983 insA 4492985 insA Escherichia coli APEC O1 IS1 InsA protein YP_859799.1 4763708 D 405955 CDS YP_859800.1 117626477 4492986 4763902..4764405 1 NC_008563.1 IS1 transposase; IS1 InsB protein 4764405 insB 4492986 insB Escherichia coli APEC O1 IS1 InsB protein YP_859800.1 4763902 D 405955 CDS YP_859801.1 117626478 4492987 complement(4764872..4765423) 1 NC_008563.1 regulator PapX protein 4765423 papX 4492987 papX Escherichia coli APEC O1 regulator PapX protein YP_859801.1 4764872 R 405955 CDS YP_859802.1 117626479 4492988 complement(4765590..4765955) 1 NC_008563.1 integrase-like protein; hypothetical protein 4765955 4492988 APECO1_2259 Escherichia coli APEC O1 hypothetical protein YP_859802.1 4765590 R 405955 CDS YP_859803.1 117626480 4492989 complement(4766031..4766357) 1 NC_008563.1 hypothetical protein 4766357 4492989 APECO1_2258 Escherichia coli APEC O1 hypothetical protein YP_859803.1 4766031 R 405955 CDS YP_859804.1 117626481 4491909 complement(4766398..4766901) 1 NC_008563.1 IS1 transposase; IS1 InsB protein 4766901 insB 4491909 insB Escherichia coli APEC O1 IS1 InsB protein YP_859804.1 4766398 R 405955 CDS YP_859805.1 117626482 4491910 complement(4766820..4767095) 1 NC_008563.1 IS1 InsA protein 4767095 insA 4491910 insA Escherichia coli APEC O1 IS1 InsA protein YP_859805.1 4766820 R 405955 CDS YP_859806.1 117626483 4491911 complement(4767625..4768698) 1 NC_008563.1 ShiA-like protein 4768698 shiA 4491911 shiA Escherichia coli APEC O1 ShiA-like protein YP_859806.1 4767625 R 405955 CDS YP_859807.1 117626484 4491912 complement(4768924..4770189) 1 NC_008563.1 Int ( P4-type integrase) 4770189 int 4491912 int Escherichia coli APEC O1 Int ( P4-type integrase) YP_859807.1 4768924 R 405955 CDS YP_859808.1 117626485 4491913 complement(4770569..4771168) 1 NC_008563.1 transcriptional regulator 4771168 yjdC 4491913 yjdC Escherichia coli APEC O1 transcriptional regulator YP_859808.1 4770569 R 405955 CDS YP_859809.1 117626486 4491914 complement(4771181..4772959) 1 NC_008563.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4772959 dipZ 4491914 dipZ Escherichia coli APEC O1 thiol:disulfide interchange protein YP_859809.1 4771181 R 405955 CDS YP_859810.1 117626487 4491915 complement(4773308..4774609) 1 NC_008563.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4774609 dcuA 4491915 dcuA Escherichia coli APEC O1 anaerobic C4-dicarboxylate transporter YP_859810.1 4773308 R 405955 CDS YP_859811.1 117626488 4491916 complement(4774727..4776208) 1 NC_008563.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4776208 aspA 4491916 aspA Escherichia coli APEC O1 aspartate ammonia-lyase YP_859811.1 4774727 R 405955 CDS YP_859812.1 117626489 4491917 4776599..4776976 1 NC_008563.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4776976 fxsA 4491917 fxsA Escherichia coli APEC O1 FxsA protein YP_859812.1 4776599 D 405955 CDS YP_859813.1 117626490 4491918 complement(4776992..4778308) 1 NC_008563.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 4778308 yjeH 4491918 yjeH Escherichia coli APEC O1 hypothetical protein YP_859813.1 4776992 R 405955 CDS YP_859814.1 117626491 4491919 complement(4778391..4778714) 1 NC_008563.1 hypothetical protein 4778714 4491919 APECO1_2247 Escherichia coli APEC O1 hypothetical protein YP_859814.1 4778391 R 405955 CDS YP_859815.1 117626492 4491920 4778861..4780507 1 NC_008563.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4780507 groEL 4491920 groEL Escherichia coli APEC O1 chaperonin GroEL YP_859815.1 4778861 D 405955 CDS YP_859816.1 117626493 4495536 4780612..4780998 1 NC_008563.1 hypothetical protein 4780998 yjeI 4495536 yjeI Escherichia coli APEC O1 hypothetical protein YP_859816.1 4780612 D 405955 CDS YP_859817.1 117626494 4495537 complement(4781048..4781917) 1 NC_008563.1 hypothetical protein 4781917 yjeJ 4495537 yjeJ Escherichia coli APEC O1 hypothetical protein YP_859817.1 4781048 R 405955 CDS YP_859818.1 117626495 4495538 complement(4782152..4783180) 1 NC_008563.1 lysine aminomutase 4783180 yjeK 4495538 yjeK Escherichia coli APEC O1 lysine aminomutase YP_859818.1 4782152 R 405955 CDS YP_859819.1 117626496 4495539 4783222..4783788 1 NC_008563.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4783788 efp 4495539 efp Escherichia coli APEC O1 elongation factor P YP_859819.1 4783222 D 405955 CDS YP_859820.1 117626497 4495540 4784398..4784715 1 NC_008563.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4784715 sugE 4495540 sugE Escherichia coli APEC O1 quaternary ammonium compound-resistance protein SugE YP_859820.1 4784398 D 405955 CDS YP_859821.1 117626498 4495541 complement(4784712..4785245) 1 NC_008563.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4785245 blc 4495541 blc Escherichia coli APEC O1 outer membrane lipoprotein Blc YP_859821.1 4784712 R 405955 CDS YP_859822.1 117626499 4495542 complement(4785334..4786596) 1 NC_008563.1 beta-lactamase 4786596 ampC 4495542 ampC Escherichia coli APEC O1 beta-lactamase YP_859822.1 4785334 R 405955 CDS YP_859823.1 117626500 4495543 complement(4786530..4786889) 1 NC_008563.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4786889 frdD 4495543 frdD Escherichia coli APEC O1 fumarate reductase subunit D YP_859823.1 4786530 R 405955 CDS YP_859824.1 117626501 4495544 complement(4786900..4787295) 1 NC_008563.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4787295 frdC 4495544 frdC Escherichia coli APEC O1 fumarate reductase subunit C YP_859824.1 4786900 R 405955 CDS YP_859825.2 229775947 4495546 complement(4787306..4788040) 1 NC_008563.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4788040 frdB 4495546 frdB Escherichia coli APEC O1 fumarate reductase iron-sulfur subunit YP_859825.2 4787306 R 405955 CDS YP_859826.1 117626503 4495547 complement(4788033..4789841) 1 NC_008563.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4789841 frdA 4495547 frdA Escherichia coli APEC O1 fumarate reductase flavoprotein subunit YP_859826.1 4788033 R 405955 CDS YP_859827.1 117626504 4495548 4790136..4791143 1 NC_008563.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4791143 yjeA 4495548 yjeA Escherichia coli APEC O1 lysyl-tRNA synthetase YP_859827.1 4790136 D 405955 CDS YP_859828.1 117626505 4495549 4791320..4792864 1 NC_008563.1 transporter 4792864 yjeM 4495549 yjeM Escherichia coli APEC O1 transporter YP_859828.1 4791320 D 405955 CDS YP_859829.1 117626506 4495550 4792927..4793241 1 NC_008563.1 hypothetical protein 4793241 yjeN 4495550 yjeN Escherichia coli APEC O1 hypothetical protein YP_859829.1 4792927 D 405955 CDS YP_859830.1 117626507 4495551 4793238..4793552 1 NC_008563.1 hypothetical protein 4793552 yjeO 4495551 yjeO Escherichia coli APEC O1 hypothetical protein YP_859830.1 4793238 D 405955 CDS YP_859831.1 117626508 4495552 complement(4793583..4796906) 1 NC_008563.1 hypothetical protein 4796906 yjeP 4495552 yjeP Escherichia coli APEC O1 hypothetical protein YP_859831.1 4793583 R 405955 CDS YP_859832.1 117626509 4495553 4796970..4797851 1 NC_008563.1 hypothetical protein 4797851 4495553 APECO1_2229 Escherichia coli APEC O1 hypothetical protein YP_859832.1 4796970 D 405955 CDS YP_859833.1 117626510 4495554 complement(4797993..4799006) 1 NC_008563.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4799006 yjeQ 4495554 yjeQ Escherichia coli APEC O1 ribosome-associated GTPase YP_859833.1 4797993 R 405955 CDS YP_859834.2 229775946 4492122 4799140..4799685 1 NC_008563.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4799685 orn 4492122 orn Escherichia coli APEC O1 oligoribonuclease YP_859834.2 4799140 D 405955 CDS YP_859836.1 117626513 4492124 complement(4800464..4801711) 1 NC_008563.1 electron transport protein YjeS 4801711 yjeS 4492124 yjeS Escherichia coli APEC O1 electron transport protein YjeS YP_859836.1 4800464 R 405955 CDS YP_859837.1 117626514 4492125 4801602..4803149 1 NC_008563.1 hypothetical protein 4803149 yjeF 4492125 yjeF Escherichia coli APEC O1 hypothetical protein YP_859837.1 4801602 D 405955 CDS YP_859838.1 117626515 4492126 4803121..4803582 1 NC_008563.1 possibly involved in cell wall synthesis; ATPase 4803582 yjeE 4492126 yjeE Escherichia coli APEC O1 ATPase YP_859838.1 4803121 D 405955 CDS YP_859839.1 117626516 4492127 4803601..4804938 1 NC_008563.1 N-acetylmuramoyl-l-alanine amidase II 4804938 amiB 4492127 amiB Escherichia coli APEC O1 N-acetylmuramoyl-l-alanine amidase II YP_859839.1 4803601 D 405955 CDS YP_859840.1 117626517 4492128 4804948..4806795 1 NC_008563.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4806795 mutL 4492128 mutL Escherichia coli APEC O1 DNA mismatch repair protein YP_859840.1 4804948 D 405955 CDS YP_859841.1 117626518 4492129 4806788..4807738 1 NC_008563.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4807738 miaA 4492129 miaA Escherichia coli APEC O1 tRNA delta(2)-isopentenylpyrophosphate transferase YP_859841.1 4806788 D 405955 CDS YP_859842.1 117626519 4492130 4807824..4808132 1 NC_008563.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4808132 hfq 4492130 hfq Escherichia coli APEC O1 RNA-binding protein Hfq YP_859842.1 4807824 D 405955 CDS YP_859843.1 117626520 4492131 4808277..4809488 1 NC_008563.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4809488 hflX 4492131 hflX Escherichia coli APEC O1 GTPase HflX YP_859843.1 4808277 D 405955 CDS YP_859844.1 117626521 4492132 4809574..4810833 1 NC_008563.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4810833 hflK 4492132 hflK Escherichia coli APEC O1 FtsH protease regulator HflK YP_859844.1 4809574 D 405955 CDS YP_859845.1 117626522 4492133 4810836..4811840 1 NC_008563.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4811840 hflC 4492133 hflC Escherichia coli APEC O1 FtsH protease regulator HflC YP_859845.1 4810836 D 405955 CDS YP_859846.1 117626523 4492134 4812223..4813521 1 NC_008563.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4813521 purA 4492134 purA Escherichia coli APEC O1 adenylosuccinate synthetase YP_859846.1 4812223 D 405955 CDS YP_859847.1 117626524 4492135 4813726..4814151 1 NC_008563.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4814151 yjeB 4492135 yjeB Escherichia coli APEC O1 transcriptional repressor NsrR YP_859847.1 4813726 D 405955 CDS YP_859848.1 117626525 4492136 4814148..4816631 1 NC_008563.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4816631 rnr 4492136 rnr Escherichia coli APEC O1 exoribonuclease R YP_859848.1 4814148 D 405955 CDS YP_859849.1 117626526 4492137 4816723..4817454 1 NC_008563.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4817454 yjfH 4492137 yjfH Escherichia coli APEC O1 23S rRNA (guanosine-2'-O-)-methyltransferase YP_859849.1 4816723 D 405955 CDS YP_859850.1 117626527 4492138 4817581..4817982 1 NC_008563.1 hypothetical protein 4817982 yjfI 4492138 yjfI Escherichia coli APEC O1 hypothetical protein YP_859850.1 4817581 D 405955 CDS YP_859851.1 117626528 4492139 4818001..4818699 1 NC_008563.1 transcriptional regulator effector protein 4818699 yjfJ 4492139 yjfJ Escherichia coli APEC O1 transcriptional regulator effector protein YP_859851.1 4818001 D 405955 CDS YP_859852.1 117626529 4492140 4818749..4819408 1 NC_008563.1 hypothetical protein 4819408 yjfK 4492140 yjfK Escherichia coli APEC O1 hypothetical protein YP_859852.1 4818749 D 405955 CDS YP_859853.1 117626530 4492141 4819345..4819824 1 NC_008563.1 hypothetical protein 4819824 yjfL 4492141 yjfL Escherichia coli APEC O1 hypothetical protein YP_859853.1 4819345 D 405955 CDS YP_859854.1 117626531 4493587 4819834..4820472 1 NC_008563.1 hypothetical protein 4820472 yjfM 4493587 yjfM Escherichia coli APEC O1 hypothetical protein YP_859854.1 4819834 D 405955 CDS YP_859855.1 117626532 4493588 4820475..4821638 1 NC_008563.1 synthetase/amidase 4821638 yjfC 4493588 yjfC Escherichia coli APEC O1 synthetase/amidase YP_859855.1 4820475 D 405955 CDS YP_859856.1 117626533 4493589 4821707..4823347 1 NC_008563.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4823347 aidB 4493589 aidB Escherichia coli APEC O1 isovaleryl CoA dehydrogenase YP_859856.1 4821707 D 405955 CDS YP_859857.1 117626534 4493590 complement(4823464..4823766) 1 NC_008563.1 hypothetical protein 4823766 yjfN 4493590 yjfN Escherichia coli APEC O1 hypothetical protein YP_859857.1 4823464 R 405955 CDS YP_859858.1 117626535 4493591 complement(4823888..4824316) 1 NC_008563.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 4824316 4493591 APECO1_2203 Escherichia coli APEC O1 biofilm stress and motility protein A YP_859858.1 4823888 R 405955 CDS YP_859859.1 117626536 4493592 4824399..4825148 1 NC_008563.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4825148 4493592 APECO1_2202 Escherichia coli APEC O1 esterase YP_859859.1 4824399 D 405955 CDS YP_859860.1 117626537 4493593 complement(4825145..4825900) 1 NC_008563.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4825900 yjfQ 4493593 yjfQ Escherichia coli APEC O1 transcriptional repressor UlaR YP_859860.1 4825145 R 405955 CDS YP_859861.1 117626538 4493594 complement(4826008..4827078) 1 NC_008563.1 L-ascorbate 6-phosphate lactonase 4827078 ulaG 4493594 ulaG Escherichia coli APEC O1 L-ascorbate 6-phosphate lactonase YP_859861.1 4826008 R 405955 CDS YP_859862.2 162317558 4493595 4827427..4828824 1 NC_008563.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4828824 ulaA 4493595 ulaA Escherichia coli APEC O1 PTS system ascorbate-specific transporter subunit IIC YP_859862.2 4827427 D 405955 CDS YP_859864.1 117626541 4493597 complement(4829161..4829493) 1 NC_008563.1 hypothetical protein 4829493 4493597 APECO1_2197 Escherichia coli APEC O1 hypothetical protein YP_859864.1 4829161 R 405955 CDS YP_859865.2 162317557 4493598 4829633..4830283 1 NC_008563.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4830283 ulaD 4493598 ulaD Escherichia coli APEC O1 3-keto-L-gulonate-6-phosphate decarboxylase YP_859865.2 4829633 D 405955 CDS YP_859866.1 117626543 4493599 4830293..4831147 1 NC_008563.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4831147 ulaE 4493599 ulaE Escherichia coli APEC O1 L-xylulose 5-phosphate 3-epimerase YP_859866.1 4830293 D 405955 CDS YP_859867.1 117626544 4493600 4831147..4831833 1 NC_008563.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4831833 sgaE 4493600 sgaE Escherichia coli APEC O1 L-ribulose-5-phosphate 4-epimerase YP_859867.1 4831147 D 405955 CDS YP_859868.1 117626545 4493601 complement(4831962..4832237) 1 NC_008563.1 hypothetical protein 4832237 yjfY 4493601 yjfY Escherichia coli APEC O1 hypothetical protein YP_859868.1 4831962 R 405955 CDS YP_859869.1 117626546 4493602 4832565..4832960 1 NC_008563.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4832960 rpsF 4493602 rpsF Escherichia coli APEC O1 30S ribosomal protein S6 YP_859869.1 4832565 D 405955 CDS YP_859870.1 117626547 4493603 4832967..4833281 1 NC_008563.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4833281 priB 4493603 priB Escherichia coli APEC O1 primosomal replication protein N YP_859870.1 4832967 D 405955 CDS YP_859871.1 117626548 4493604 4833555..4834004 1 NC_008563.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4834004 rplI 4493604 rplI Escherichia coli APEC O1 50S ribosomal protein L9 YP_859871.1 4833555 D 405955 CDS YP_859872.1 117626549 4493605 4834406..4834897 1 NC_008563.1 hypothetical protein 4834897 4493605 APECO1_2189 Escherichia coli APEC O1 hypothetical protein YP_859872.1 4834406 D 405955 CDS YP_859873.1 117626550 4495230 4834900..4836168 1 NC_008563.1 hypothetical protein 4836168 4495230 APECO1_2188 Escherichia coli APEC O1 hypothetical protein YP_859873.1 4834900 D 405955 CDS YP_859874.1 117626551 4495231 complement(4836311..4837588) 1 NC_008563.1 hexuronate transporter 4837588 4495231 APECO1_2187 Escherichia coli APEC O1 hexuronate transporter YP_859874.1 4836311 R 405955 CDS YP_859875.1 117626552 4495232 complement(4837681..4839753) 1 NC_008563.1 oxidoreductase 4839753 4495232 APECO1_2186 Escherichia coli APEC O1 oxidoreductase YP_859875.1 4837681 R 405955 CDS YP_859876.1 117626553 4495233 complement(4839750..4841291) 1 NC_008563.1 acetyl-CoA:acetoacetyl-CoA transferase 4841291 4495233 APECO1_2185 Escherichia coli APEC O1 acetyl-CoA:acetoacetyl-CoA transferase YP_859876.1 4839750 R 405955 CDS YP_859877.1 117626554 4495235 complement(4841301..4842077) 1 NC_008563.1 hypothetical protein 4842077 4495235 APECO1_2184 Escherichia coli APEC O1 hypothetical protein YP_859877.1 4841301 R 405955 CDS YP_859878.1 117626555 4495236 complement(4842080..4842928) 1 NC_008563.1 hypothetical protein 4842928 4495236 APECO1_2183 Escherichia coli APEC O1 hypothetical protein YP_859878.1 4842080 R 405955 CDS YP_859879.2 162317556 4495237 complement(4842938..4843729) 1 NC_008563.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4843729 4495237 APECO1_2182 Escherichia coli APEC O1 3-ketoacyl-ACP reductase YP_859879.2 4842938 R 405955 CDS YP_859880.1 117626557 4495238 4843905..4844588 1 NC_008563.1 transcriptional regulator 4844588 4495238 APECO1_2181 Escherichia coli APEC O1 transcriptional regulator YP_859880.1 4843905 D 405955 CDS YP_859881.1 117626558 4495239 complement(4844572..4845246) 1 NC_008563.1 cell envelope opacity-associated protein 4845246 ytfB 4495239 ytfB Escherichia coli APEC O1 cell envelope opacity-associated protein YP_859881.1 4844572 R 405955 CDS YP_859882.1 117626559 4495240 4845269..4846048 1 NC_008563.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4846048 fklB 4495240 fklB Escherichia coli APEC O1 peptidyl-prolyl cis-trans isomerase YP_859882.1 4845269 D 405955 CDS YP_859883.1 117626560 4495241 4846357..4847769 1 NC_008563.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4847769 cycA 4495241 cycA Escherichia coli APEC O1 D-alanine/D-serine/glycine permease YP_859883.1 4846357 D 405955 CDS YP_859884.1 117626561 4495242 complement(4847814..4848476) 1 NC_008563.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4848476 ytfE 4495242 ytfE Escherichia coli APEC O1 iron-sulfur cluster repair di-iron protein YP_859884.1 4847814 R 405955 CDS YP_859885.1 117626562 4495244 complement(4848584..4849558) 1 NC_008563.1 hypothetical protein 4849558 ytfF 4495244 ytfF Escherichia coli APEC O1 hypothetical protein YP_859885.1 4848584 R 405955 CDS YP_859886.1 117626563 4495245 complement(4849657..4850517) 1 NC_008563.1 hypothetical protein 4850517 ytfG 4495245 ytfG Escherichia coli APEC O1 hypothetical protein YP_859886.1 4849657 R 405955 CDS YP_859887.1 117626564 4495246 4850495..4850986 1 NC_008563.1 hypothetical protein 4850986 ytfH 4495246 ytfH Escherichia coli APEC O1 hypothetical protein YP_859887.1 4850495 D 405955 CDS YP_859888.1 117626565 4495247 complement(4851115..4853067) 1 NC_008563.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4853067 cpdB 4495247 cpdB Escherichia coli APEC O1 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_859888.1 4851115 R 405955 CDS YP_859889.1 117626566 4493048 4853248..4853988 1 NC_008563.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4853988 cysQ 4493048 cysQ Escherichia coli APEC O1 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_859889.1 4853248 D 405955 CDS YP_859890.1 117626567 4493049 complement(4853978..4854535) 1 NC_008563.1 hypothetical protein 4854535 ytfJ 4493049 ytfJ Escherichia coli APEC O1 hypothetical protein YP_859890.1 4853978 R 405955 CDS YP_859891.1 117626568 4493050 complement(4855144..4856487) 1 NC_008563.1 transporter 4856487 ytfL 4493050 ytfL Escherichia coli APEC O1 transporter YP_859891.1 4855144 R 405955 CDS YP_859892.1 117626569 4493051 complement(4856810..4857475) 1 NC_008563.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4857475 msrA 4493051 msrA Escherichia coli APEC O1 methionine sulfoxide reductase A YP_859892.1 4856810 R 405955 CDS YP_859893.1 117626570 4493052 4857654..4859387 1 NC_008563.1 outer membrane protein 4859387 ytfM 4493052 ytfM Escherichia coli APEC O1 outer membrane protein YP_859893.1 4857654 D 405955 CDS YP_859894.1 117626571 4493053 4859384..4863163 1 NC_008563.1 hypothetical protein 4863163 ytfN 4493053 ytfN Escherichia coli APEC O1 hypothetical protein YP_859894.1 4859384 D 405955 CDS YP_859895.1 117626572 4493054 4863166..4863507 1 NC_008563.1 hypothetical protein 4863507 4493054 APECO1_2166 Escherichia coli APEC O1 hypothetical protein YP_859895.1 4863166 D 405955 CDS YP_859896.1 117626573 4493055 complement(4863887..4864417) 1 NC_008563.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4864417 ppa 4493055 ppa Escherichia coli APEC O1 inorganic pyrophosphatase YP_859896.1 4863887 R 405955 CDS YP_859897.1 117626574 4493056 4864727..4865683 1 NC_008563.1 ABC transporter substrate-binding protein 4865683 ytfQ 4493056 ytfQ Escherichia coli APEC O1 ABC transporter substrate-binding protein YP_859897.1 4864727 D 405955 CDS YP_859898.1 117626575 4493057 4865823..4867325 1 NC_008563.1 ATP-binding component of a transport system 4867325 ytfR 4493057 ytfR Escherichia coli APEC O1 ATP-binding component of a transport system YP_859898.1 4865823 D 405955 CDS YP_859899.1 117626576 4493058 4867336..4868361 1 NC_008563.1 ABC transporter permease 4868361 ytfT 4493058 ytfT Escherichia coli APEC O1 ABC transporter permease YP_859899.1 4867336 D 405955 CDS YP_859900.1 117626577 4493059 4868348..4869343 1 NC_008563.1 membrane component of a sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4869343 yjfF 4493059 yjfF Escherichia coli APEC O1 inner membrane ABC transporter permease YjfF YP_859900.1 4868348 D 405955 CDS YP_859901.1 117626578 4493060 complement(4869376..4870374) 1 NC_008563.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4870374 fbp 4493060 fbp Escherichia coli APEC O1 fructose-1,6-bisphosphatase YP_859901.1 4869376 R 405955 CDS YP_859902.1 117626579 4493061 4870550..4871923 1 NC_008563.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4871923 mpl 4493061 mpl Escherichia coli APEC O1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_859902.1 4870550 D 405955 CDS YP_859903.1 117626580 4493062 complement(4872081..4872632) 1 NC_008563.1 hypothetical protein 4872632 yjgA 4493062 yjgA Escherichia coli APEC O1 hypothetical protein YP_859903.1 4872081 R 405955 CDS YP_859904.1 117626581 4493063 4872726..4874078 1 NC_008563.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4874078 pmbA 4493063 pmbA Escherichia coli APEC O1 peptidase PmbA YP_859904.1 4872726 D 405955 CDS YP_859905.1 117626582 4493064 4874262..4874648 1 NC_008563.1 soluble cytochrome b562 4874648 cybC 4493064 cybC Escherichia coli APEC O1 soluble cytochrome b562 YP_859905.1 4874262 D 405955 CDS YP_859906.1 117626583 4493065 complement(4874693..4875157) 1 NC_008563.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4875157 nrdG 4493065 nrdG Escherichia coli APEC O1 anaerobic ribonucleotide reductase-activating protein YP_859906.1 4874693 R 405955 CDS YP_859907.1 117626584 4493066 complement(4875315..4877453) 1 NC_008563.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4877453 nrdD 4493066 nrdD Escherichia coli APEC O1 anaerobic ribonucleoside triphosphate reductase YP_859907.1 4875315 R 405955 CDS YP_859908.1 117626585 4494061 complement(4877847..4879502) 1 NC_008563.1 trehalose-6-phosphate hydrolase 4879502 treC 4494061 treC Escherichia coli APEC O1 trehalose-6-phosphate hydrolase YP_859908.1 4877847 R 405955 CDS YP_859909.1 117626586 4494062 complement(4879552..4880973) 1 NC_008563.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4880973 treB 4494062 treB Escherichia coli APEC O1 PTS system trehalose(maltose)-specific transporter subunit IIBC YP_859909.1 4879552 R 405955 CDS YP_859910.1 117626587 4494063 complement(4881092..4882039) 1 NC_008563.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4882039 treR 4494063 treR Escherichia coli APEC O1 trehalose repressor YP_859910.1 4881092 R 405955 CDS YP_859911.1 117626588 4494064 4882418..4885114 1 NC_008563.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4885114 mgtA 4494064 mgtA Escherichia coli APEC O1 magnesium-transporting ATPase MgtA YP_859911.1 4882418 D 405955 CDS YP_859912.1 117626589 4494065 complement(4885320..4885745) 1 NC_008563.1 hypothetical protein 4885745 yjgF 4494065 yjgF Escherichia coli APEC O1 hypothetical protein YP_859912.1 4885320 R 405955 CDS YP_859913.1 117626590 4494066 complement(4885779..4886240) 1 NC_008563.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4886240 pyrI 4494066 pyrI Escherichia coli APEC O1 aspartate carbamoyltransferase regulatory subunit YP_859913.1 4885779 R 405955 CDS YP_859914.1 117626591 4494067 complement(4886253..4887188) 1 NC_008563.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4887188 pyrB 4494067 pyrB Escherichia coli APEC O1 aspartate carbamoyltransferase catalytic subunit YP_859914.1 4886253 R 405955 CDS YP_859915.1 117626592 4494068 complement(4887416..4887970) 1 NC_008563.1 arganine repressor 4887970 4494068 APECO1_2146 Escherichia coli APEC O1 arganine repressor YP_859915.1 4887416 R 405955 CDS YP_859916.1 117626593 4494069 complement(4888020..4888973) 1 NC_008563.1 hypothetical protein 4888973 4494069 APECO1_2145 Escherichia coli APEC O1 hypothetical protein YP_859916.1 4888020 R 405955 CDS YP_859917.1 117626594 4494070 complement(4889480..4890484) 1 NC_008563.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 4890484 argF 4494070 argF Escherichia coli APEC O1 ornithine carbamoyltransferase YP_859917.1 4889480 R 405955 CDS YP_859918.2 162317555 4494071 complement(4890495..4891439) 1 NC_008563.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4891439 4494071 APECO1_2143 Escherichia coli APEC O1 carbamate kinase YP_859918.2 4890495 R 405955 CDS YP_859919.1 117626596 4494072 complement(4891450..4892673) 1 NC_008563.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 4892673 4494072 APECO1_2142 Escherichia coli APEC O1 arginine deiminase YP_859919.1 4891450 R 405955 CDS YP_859920.1 117626597 4494073 4893348..4893800 1 NC_008563.1 hypothetical protein 4893800 yjgK 4494073 yjgK Escherichia coli APEC O1 hypothetical protein YP_859920.1 4893348 D 405955 CDS YP_859921.1 117626598 4494074 complement(4893846..4895054) 1 NC_008563.1 ornithine carbamoyltransferase 1 4895054 argI 4494074 argI Escherichia coli APEC O1 ornithine carbamoyltransferase 1 YP_859921.1 4893846 R 405955 CDS YP_859922.1 117626599 4494075 4895012..4895428 1 NC_008563.1 hypothetical protein 4895428 yjgD 4494075 yjgD Escherichia coli APEC O1 hypothetical protein YP_859922.1 4895012 D 405955 CDS YP_859923.1 117626600 4494076 complement(4895605..4896108) 1 NC_008563.1 acetyltransferase YjgM 4896108 yjgM 4494076 yjgM Escherichia coli APEC O1 acetyltransferase YjgM YP_859923.1 4895605 R 405955 CDS YP_859924.1 117626601 4494077 4896301..4897488 1 NC_008563.1 hypothetical protein 4897488 yjgN 4494077 yjgN Escherichia coli APEC O1 hypothetical protein YP_859924.1 4896301 D 405955 CDS YP_859925.1 117626602 4494078 complement(4897535..4900390) 1 NC_008563.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4900390 valS 4494078 valS Escherichia coli APEC O1 valyl-tRNA synthetase YP_859925.1 4897535 R 405955 CDS YP_859926.1 117626603 4494079 complement(4900390..4900833) 1 NC_008563.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4900833 holC 4494079 holC Escherichia coli APEC O1 DNA polymerase III subunit chi YP_859926.1 4900390 R 405955 CDS YP_859927.1 117626604 4494080 complement(4901091..4902602) 1 NC_008563.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4902602 pepA 4494080 pepA Escherichia coli APEC O1 leucyl aminopeptidase YP_859927.1 4901091 R 405955 CDS YP_859928.1 117626605 4493908 4902869..4903969 1 NC_008563.1 hypothetical protein 4903969 4493908 APECO1_2133 Escherichia coli APEC O1 hypothetical protein YP_859928.1 4902869 D 405955 CDS YP_859929.1 117626606 4493909 4903966..4905051 1 NC_008563.1 hypothetical protein 4905051 yjgQ 4493909 yjgQ Escherichia coli APEC O1 hypothetical protein YP_859929.1 4903966 D 405955 CDS YP_859930.1 117626607 4493910 complement(4905186..4906715) 1 NC_008563.1 hypothetical protein 4906715 yjgR 4493910 yjgR Escherichia coli APEC O1 hypothetical protein YP_859930.1 4905186 R 405955 CDS YP_859931.1 117626608 4493911 complement(4906793..4907791) 1 NC_008563.1 L-idonate regulatory protein 4907791 idnR 4493911 idnR Escherichia coli APEC O1 L-idonate regulatory protein YP_859931.1 4906793 R 405955 CDS YP_859932.1 117626609 4493912 complement(4907858..4909177) 1 NC_008563.1 L-idonate and D-gluconate transporter 4909177 idnT 4493912 idnT Escherichia coli APEC O1 L-idonate and D-gluconate transporter YP_859932.1 4907858 R 405955 CDS YP_859933.1 117626610 4493913 complement(4909242..4910006) 1 NC_008563.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 4910006 idnO 4493913 idnO Escherichia coli APEC O1 gluconate 5-dehydrogenase YP_859933.1 4909242 R 405955 CDS YP_859934.1 117626611 4493914 complement(4910030..4911061) 1 NC_008563.1 NAD-binding; L-idonate 5-dehydrogenase 4911061 idnD 4493914 idnD Escherichia coli APEC O1 L-idonate 5-dehydrogenase YP_859934.1 4910030 R 405955 CDS YP_859935.1 117626612 4493915 4911278..4911841 1 NC_008563.1 D-gluconate kinase 4911841 idnK 4493915 idnK Escherichia coli APEC O1 D-gluconate kinase YP_859935.1 4911278 D 405955 CDS YP_859936.1 117626613 4493916 complement(4911845..4912906) 1 NC_008563.1 oxidoreductase 4912906 yjgB 4493916 yjgB Escherichia coli APEC O1 oxidoreductase YP_859936.1 4911845 R 405955 CDS YP_859937.1 117626614 4493917 4913953..4915869 1 NC_008563.1 hypothetical protein 4915869 4493917 APECO1_2124 Escherichia coli APEC O1 hypothetical protein YP_859937.1 4913953 D 405955 CDS YP_859938.1 117626615 4493918 complement(4916492..4917397) 1 NC_008563.1 hypothetical protein 4917397 4493918 APECO1_2123 Escherichia coli APEC O1 hypothetical protein YP_859938.1 4916492 R 405955 CDS YP_859939.1 117626616 4493919 complement(4917576..4918556) 1 NC_008563.1 hypothetical protein 4918556 yjhS 4493919 yjhS Escherichia coli APEC O1 hypothetical protein YP_859939.1 4917576 R 405955 CDS YP_859940.1 117626617 4493920 complement(4918621..4919835) 1 NC_008563.1 N-acetylneuraminic acid mutarotase 4919835 yjhT 4493920 yjhT Escherichia coli APEC O1 N-acetylneuraminic acid mutarotase YP_859940.1 4918621 R 405955 CDS YP_859941.1 117626618 4493921 complement(4919747..4920472) 1 NC_008563.1 hypothetical protein 4920472 yjhA 4493921 yjhA Escherichia coli APEC O1 hypothetical protein YP_859941.1 4919747 R 405955 CDS YP_859942.1 117626619 4493922 complement(4921262..4921669) 1 NC_008563.1 hypothetical protein 4921669 4493922 APECO1_2119 Escherichia coli APEC O1 hypothetical protein YP_859942.1 4921262 R 405955 CDS YP_859943.1 117626620 4493923 4921929..4922531 1 NC_008563.1 inversion of on/off regulator of fimA; tyrosine recombinase 4922531 fimB 4493923 fimB Escherichia coli APEC O1 tyrosine recombinase YP_859943.1 4921929 D 405955 CDS YP_859944.1 117626621 4493924 4923009..4923605 1 NC_008563.1 inversion of on/off regulator of fimA; tyrosine recombinase 4923605 fimE 4493924 fimE Escherichia coli APEC O1 tyrosine recombinase YP_859944.1 4923009 D 405955 CDS YP_859945.1 117626622 4493925 4924029..4924640 1 NC_008563.1 type 1 fimbriae major subunit FimA 4924640 fimA 4493925 fimA Escherichia coli APEC O1 type 1 fimbriae major subunit FimA YP_859945.1 4924029 D 405955 CDS YP_859946.1 117626623 4493926 4924582..4925244 1 NC_008563.1 FimI fimbrial protein 4925244 fimI 4493926 fimI Escherichia coli APEC O1 FimI fimbrial protein YP_859946.1 4924582 D 405955 CDS YP_859947.1 117626624 4492142 4925281..4926006 1 NC_008563.1 type I fimbrial chaperone 4926006 fimC 4492142 fimC Escherichia coli APEC O1 type I fimbrial chaperone YP_859947.1 4925281 D 405955 CDS YP_859948.1 117626625 4492143 4926072..4928708 1 NC_008563.1 outer membrane usher protein FimD 4928708 fimD 4492143 fimD Escherichia coli APEC O1 outer membrane usher protein FimD YP_859948.1 4926072 D 405955 CDS YP_859949.1 117626626 4492144 4928715..4929248 1 NC_008563.1 FimF protein 4929248 4492144 APECO1_2112 Escherichia coli APEC O1 FimF protein YP_859949.1 4928715 D 405955 CDS YP_859950.1 117626627 4492145 4929255..4929764 1 NC_008563.1 P pilus assembly protein, pilin FimA 4929764 fimA 4492145 fimA Escherichia coli APEC O1 P pilus assembly protein, pilin FimA YP_859950.1 4929255 D 405955 CDS YP_859951.1 117626628 4492146 4929775..4930686 1 NC_008563.1 type 1 fimbiral adhesin FimH 4930686 fimH 4492146 fimH Escherichia coli APEC O1 type 1 fimbiral adhesin FimH YP_859951.1 4929775 D 405955 CDS YP_859952.1 117626629 4492147 4931415..4932599 1 NC_008563.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4932599 uxuA 4492147 uxuA Escherichia coli APEC O1 mannonate dehydratase YP_859952.1 4931415 D 405955 CDS YP_859953.1 117626630 4492148 4932680..4934140 1 NC_008563.1 D-mannonate oxidoreductase 4934140 uxuB 4492148 uxuB Escherichia coli APEC O1 D-mannonate oxidoreductase YP_859953.1 4932680 D 405955 CDS YP_859954.1 117626631 4492149 4934355..4935128 1 NC_008563.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4935128 uxuR 4492149 uxuR Escherichia coli APEC O1 DNA-binding transcriptional repressor UxuR YP_859954.1 4934355 D 405955 CDS YP_859955.1 117626632 4492150 4935533..4935925 1 NC_008563.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4935925 iraD 4492150 iraD Escherichia coli APEC O1 DNA replication/recombination/repair protein YP_859955.1 4935533 D 405955 CDS YP_859956.1 117626633 4492151 complement(4935973..4938354) 1 NC_008563.1 phosphoenolpyruvate-protein phosphoryltransferase PptE 4938354 pptE 4492151 pptE Escherichia coli APEC O1 phosphoenolpyruvate-protein phosphoryltransferase PptE YP_859956.1 4935973 R 405955 CDS YP_859957.1 117626634 4492152 complement(4938358..4938990) 1 NC_008563.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 4938990 ptnK 4492152 ptnK Escherichia coli APEC O1 dihydroxyacetone kinase subunit DhaL YP_859957.1 4938358 R 405955 CDS YP_859958.1 117626635 4492153 complement(4939003..4940073) 1 NC_008563.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 4940073 ptnC 4492153 ptnC Escherichia coli APEC O1 dihydroxyacetone kinase subunit DhaK YP_859958.1 4939003 R 405955 CDS YP_859959.1 117626636 4492154 4940392..4941474 1 NC_008563.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4941474 gldA 4492154 gldA Escherichia coli APEC O1 glycerol dehydrogenase YP_859959.1 4940392 D 405955 CDS YP_859960.1 117626637 4492155 4941541..4942809 1 NC_008563.1 transporter 4942809 4492155 APECO1_2101 Escherichia coli APEC O1 transporter YP_859960.1 4941541 D 405955 CDS YP_859961.1 117626638 4492156 4942827..4944191 1 NC_008563.1 dihydrolipoamide dehydrogenase 4944191 4492156 APECO1_2100 Escherichia coli APEC O1 dihydrolipoamide dehydrogenase YP_859961.1 4942827 D 405955 CDS YP_859962.1 117626639 4492157 4944492..4946033 1 NC_008563.1 carnitine transporter CniT 4946033 cniT 4492157 cniT Escherichia coli APEC O1 carnitine transporter CniT YP_859962.1 4944492 D 405955 CDS YP_859963.1 117626640 4492158 complement(4946089..4947231) 1 NC_008563.1 glycerate kinase 4947231 gclK 4492158 gclK Escherichia coli APEC O1 glycerate kinase YP_859963.1 4946089 R 405955 CDS YP_859964.1 117626641 4492159 complement(4947306..4948193) 1 NC_008563.1 3-hydroxyisobutyrate dehydrogenase 4948193 ghbD 4492159 ghbD Escherichia coli APEC O1 3-hydroxyisobutyrate dehydrogenase YP_859964.1 4947306 R 405955 CDS YP_859965.1 117626642 4492160 complement(4948211..4948993) 1 NC_008563.1 regulatory protein GclR 4948993 gclR 4492160 gclR Escherichia coli APEC O1 regulatory protein GclR YP_859965.1 4948211 R 405955 CDS YP_859966.1 117626643 4492161 complement(4949006..4950745) 1 NC_008563.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 4950745 gclA 4492161 gclA Escherichia coli APEC O1 glyoxylate carboligase YP_859966.1 4949006 R 405955 CDS YP_859967.1 117626644 4493340 4951124..4953073 1 NC_008563.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 4953073 ibeR 4493340 ibeR Escherichia coli APEC O1 DNA-binding transcriptional regulator DhaR YP_859967.1 4951124 D 405955 CDS YP_859968.1 117626645 4493341 4953360..4954730 1 NC_008563.1 invasion protein IbeA 4954730 ibeA 4493341 ibeA Escherichia coli APEC O1 invasion protein IbeA YP_859968.1 4953360 D 405955 CDS YP_859969.1 117626646 4493342 4954745..4956148 1 NC_008563.1 transporter IbeT 4956148 ibeT 4493342 ibeT Escherichia coli APEC O1 transporter IbeT YP_859969.1 4954745 D 405955 CDS YP_859970.1 117626647 4493343 complement(4956235..4956963) 1 NC_008563.1 DNA-binding transcriptional regulator 4956963 yjiE 4493343 yjiE Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_859970.1 4956235 R 405955 CDS YP_859971.1 117626648 4493344 complement(4957211..4958383) 1 NC_008563.1 isoaspartyl dipeptidase 4958383 iadA 4493344 iadA Escherichia coli APEC O1 isoaspartyl dipeptidase YP_859971.1 4957211 R 405955 CDS YP_859972.1 117626649 4493345 complement(4958396..4958857) 1 NC_008563.1 hypothetical protein 4958857 yjiG 4493345 yjiG Escherichia coli APEC O1 hypothetical protein YP_859972.1 4958396 R 405955 CDS YP_859973.1 117626650 4493346 complement(4958854..4959549) 1 NC_008563.1 hypothetical protein 4959549 yjiH 4493346 yjiH Escherichia coli APEC O1 hypothetical protein YP_859973.1 4958854 R 405955 CDS YP_859974.1 117626651 4493347 4959685..4960146 1 NC_008563.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4960146 yjiI 4493347 yjiI Escherichia coli APEC O1 RNA 2'-phosphotransferase-like protein YP_859974.1 4959685 D 405955 CDS YP_859975.1 117626652 4493348 complement(4960353..4961531) 1 NC_008563.1 permease 4961531 yjiJ 4493348 yjiJ Escherichia coli APEC O1 permease YP_859975.1 4960353 R 405955 CDS YP_859976.1 117626653 4493349 complement(4961599..4962570) 1 NC_008563.1 hypothetical protein 4962570 yjiK 4493349 yjiK Escherichia coli APEC O1 hypothetical protein YP_859976.1 4961599 R 405955 CDS YP_859977.1 117626654 4493350 complement(4962778..4963551) 1 NC_008563.1 ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase 4963551 yjiL 4493350 yjiL Escherichia coli APEC O1 ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase YP_859977.1 4962778 R 405955 CDS YP_859978.1 117626655 4493351 complement(4963555..4964727) 1 NC_008563.1 2-hydroxyglutaryl-CoA dehydratase 4964727 yjiM 4493351 yjiM Escherichia coli APEC O1 2-hydroxyglutaryl-CoA dehydratase YP_859978.1 4963555 R 405955 CDS YP_859979.1 117626656 4493352 complement(4964822..4966102) 1 NC_008563.1 hypothetical protein 4966102 yjiN 4493352 yjiN Escherichia coli APEC O1 hypothetical protein YP_859979.1 4964822 R 405955 CDS YP_859980.1 117626657 4493353 4966287..4967207 1 NC_008563.1 hypothetical protein 4967207 yjiP 4493353 yjiP Escherichia coli APEC O1 hypothetical protein YP_859980.1 4966287 D 405955 CDS YP_859981.1 117626658 4493354 4967505..4969706 1 NC_008563.1 hypothetical protein 4969706 4493354 APECO1_2080 Escherichia coli APEC O1 hypothetical protein YP_859981.1 4967505 D 405955 CDS YP_859982.1 117626659 4493355 complement(4969753..4970151) 1 NC_008563.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 4970151 yjiW 4493355 yjiW Escherichia coli APEC O1 endoribonuclease SymE YP_859982.1 4969753 R 405955 CDS YP_859983.1 117626660 4493356 complement(4970323..4971690) 1 NC_008563.1 specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS 4971690 hsdS 4493356 hsdS Escherichia coli APEC O1 EcoKI restriction-modification system protein HsdS YP_859983.1 4970323 R 405955 CDS YP_859984.1 117626661 4493357 complement(4971687..4973276) 1 NC_008563.1 DNA methylase M 4973276 hsdM 4493357 hsdM Escherichia coli APEC O1 DNA methylase M YP_859984.1 4971687 R 405955 CDS YP_859985.1 117626662 4493358 complement(4973478..4976990) 1 NC_008563.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R 4976990 hsdR 4493358 hsdR Escherichia coli APEC O1 type I restriction enzyme EcoKI subunit R YP_859985.1 4973478 R 405955 CDS YP_859986.1 117626663 4494932 4977178..4978092 1 NC_008563.1 methylated adenine and cytosine restriction protein 4978092 mrr 4494932 mrr Escherichia coli APEC O1 methylated adenine and cytosine restriction protein YP_859986.1 4977178 D 405955 CDS YP_859987.1 117626664 4494933 complement(4978138..4979178) 1 NC_008563.1 GTP-binding protein YjiA 4979178 yjiA 4494933 yjiA Escherichia coli APEC O1 GTP-binding protein YjiA YP_859987.1 4978138 R 405955 CDS YP_859988.1 117626665 4494934 complement(4979426..4981591) 1 NC_008563.1 carbon starvation protein 4981591 yjiY 4494934 yjiY Escherichia coli APEC O1 carbon starvation protein YP_859988.1 4979426 R 405955 CDS YP_859989.1 117626666 4494935 4981953..4983608 1 NC_008563.1 methyl-accepting chemotaxis protein I, serine sensor receptor 4983608 tsr 4494935 tsr Escherichia coli APEC O1 methyl-accepting chemotaxis protein I, serine sensor receptor YP_859989.1 4981953 D 405955 CDS YP_859990.1 117626667 4494936 complement(4983651..4984922) 1 NC_008563.1 C4-dicarboxylate transport system permease large protein 4984922 4494936 APECO1_2071 Escherichia coli APEC O1 C4-dicarboxylate transport system permease large protein YP_859990.1 4983651 R 405955 CDS YP_859991.1 117626668 4494937 complement(4984919..4985392) 1 NC_008563.1 C4-dicarboxylate transport system permease small protein 4985392 4494937 APECO1_2070 Escherichia coli APEC O1 C4-dicarboxylate transport system permease small protein YP_859991.1 4984919 R 405955 CDS YP_859992.1 117626669 4494938 complement(4985456..4986427) 1 NC_008563.1 C4-dicarboxylate-binding protein 4986427 4494938 APECO1_2069 Escherichia coli APEC O1 C4-dicarboxylate-binding protein YP_859992.1 4985456 R 405955 CDS YP_859993.1 117626670 4494939 4987097..4988770 1 NC_008563.1 Na(+)/H(+) exchanger YjcE 4988770 yjcE 4494939 yjcE Escherichia coli APEC O1 Na(+)/H(+) exchanger YjcE YP_859993.1 4987097 D 405955 CDS YP_859994.1 117626671 4494940 complement(4988941..4989846) 1 NC_008563.1 DNA-binding transcriptional regulator 4989846 yjjM 4494940 yjjM Escherichia coli APEC O1 DNA-binding transcriptional regulator YP_859994.1 4988941 R 405955 CDS YP_859995.1 117626672 4494941 4989985..4991007 1 NC_008563.1 oxidoreductase, Zn-dependent and NAD(P)-binding 4991007 yjjN 4494941 yjjN Escherichia coli APEC O1 oxidoreductase, Zn-dependent and NAD(P)-binding YP_859995.1 4989985 D 405955 CDS YP_859996.1 117626673 4494942 complement(4991147..4993399) 1 NC_008563.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4993399 mdoB 4494942 mdoB Escherichia coli APEC O1 phosphoglycerol transferase I YP_859996.1 4991147 R 405955 CDS YP_859997.1 117626674 4494943 complement(4993692..4994189) 1 NC_008563.1 hypothetical protein 4994189 yjjA 4494943 yjjA Escherichia coli APEC O1 hypothetical protein YP_859997.1 4993692 R 405955 CDS YP_859998.1 117626675 4494944 complement(4994235..4994972) 1 NC_008563.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4994972 dnaC 4494944 dnaC Escherichia coli APEC O1 DNA replication protein DnaC YP_859998.1 4994235 R 405955 CDS YP_859999.1 117626676 4494945 complement(4994975..4995514) 1 NC_008563.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4995514 dnaT 4494945 dnaT Escherichia coli APEC O1 primosomal protein DnaI YP_859999.1 4994975 R 405955 CDS YP_860000.1 117626677 4494946 complement(4995622..4996095) 1 NC_008563.1 hypothetical protein 4996095 yjjB 4494946 yjjB Escherichia coli APEC O1 hypothetical protein YP_860000.1 4995622 R 405955 CDS YP_860001.1 117626678 4494947 complement(4996086..4996919) 1 NC_008563.1 hypothetical protein 4996919 yjjP 4494947 yjjP Escherichia coli APEC O1 hypothetical protein YP_860001.1 4996086 R 405955 CDS YP_860002.1 117626679 4494948 4997476..4998201 1 NC_008563.1 global regulator; hypothetical protein 4998201 yjjQ 4494948 yjjQ Escherichia coli APEC O1 hypothetical protein YP_860002.1 4997476 D 405955 CDS YP_860003.1 117626680 4494949 4998159..4998836 1 NC_008563.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; BglJ family transcriptional regulator 4998836 bglJ 4494949 bglJ Escherichia coli APEC O1 BglJ family transcriptional regulator YP_860003.1 4998159 D 405955 CDS YP_860004.1 117626681 4494950 complement(4998874..4999662) 1 NC_008563.1 ferric hydroximate transport ferric iron reductase 4999662 fhuF 4494950 fhuF Escherichia coli APEC O1 ferric hydroximate transport ferric iron reductase YP_860004.1 4998874 R 405955 CDS YP_860005.1 117626682 4494951 4999764..5000039 1 NC_008563.1 hypothetical protein 5000039 4494951 APECO1_2056 Escherichia coli APEC O1 hypothetical protein YP_860005.1 4999764 D 405955 CDS YP_860006.1 117626683 4495367 complement(5000601..5001632) 1 NC_008563.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 5001632 rsmC 4495367 rsmC Escherichia coli APEC O1 16S ribosomal RNA m2G1207 methyltransferase YP_860006.1 5000601 R 405955 CDS YP_860008.1 117626685 4495369 5002117..5002563 1 NC_008563.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5002563 rimI 4495369 rimI Escherichia coli APEC O1 ribosomal-protein-alanine N-acetyltransferase YP_860008.1 5002117 D 405955 CDS YP_860009.1 117626686 4495370 5002578..5003255 1 NC_008563.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5003255 yjjG 4495370 yjjG Escherichia coli APEC O1 nucleotidase YP_860009.1 5002578 D 405955 CDS YP_860010.1 117626687 4495371 5003641..5004855 1 NC_008563.1 hypothetical protein 5004855 4495371 APECO1_2052 Escherichia coli APEC O1 hypothetical protein YP_860010.1 5003641 D 405955 CDS YP_860011.1 117626688 4495372 complement(5005231..5006226) 1 NC_008563.1 hypothetical protein 5006226 4495372 APECO1_2051 Escherichia coli APEC O1 hypothetical protein YP_860011.1 5005231 R 405955 CDS YP_860012.1 117626689 4495373 complement(5006794..5007414) 1 NC_008563.1 hypothetical protein 5007414 4495373 APECO1_2050 Escherichia coli APEC O1 hypothetical protein YP_860012.1 5006794 R 405955 CDS YP_860013.1 117626690 4495374 complement(5007414..5007776) 1 NC_008563.1 hypothetical protein 5007776 4495374 APECO1_2049 Escherichia coli APEC O1 hypothetical protein YP_860013.1 5007414 R 405955 CDS YP_860014.1 117626691 4495375 complement(5007767..5008333) 1 NC_008563.1 hypothetical protein 5008333 yfdR 4495375 yfdR Escherichia coli APEC O1 hypothetical protein YP_860014.1 5007767 R 405955 CDS YP_860015.1 117626692 4495376 complement(5008431..5009255) 1 NC_008563.1 hypothetical protein 5009255 yfdQ 4495376 yfdQ Escherichia coli APEC O1 hypothetical protein YP_860015.1 5008431 R 405955 CDS YP_860016.1 117626693 4495377 complement(5009321..5009701) 1 NC_008563.1 hypothetical protein 5009701 4495377 APECO1_2046 Escherichia coli APEC O1 hypothetical protein YP_860016.1 5009321 R 405955 CDS YP_860017.1 117626694 4495378 complement(5010406..5011098) 1 NC_008563.1 regulatory protein 5011098 4495378 APECO1_2045 Escherichia coli APEC O1 regulatory protein YP_860017.1 5010406 R 405955 CDS YP_860018.1 117626695 4495379 5011196..5011456 1 NC_008563.1 hypothetical protein 5011456 4495379 APECO1_2044 Escherichia coli APEC O1 hypothetical protein YP_860018.1 5011196 D 405955 CDS YP_860019.1 117626696 4495380 5011449..5012000 1 NC_008563.1 hypothetical protein 5012000 4495380 APECO1_2043 Escherichia coli APEC O1 hypothetical protein YP_860019.1 5011449 D 405955 CDS YP_860020.1 117626697 4495381 5011997..5013148 1 NC_008563.1 phage-related; antirepressor 5013148 4495381 APECO1_2042 Escherichia coli APEC O1 antirepressor YP_860020.1 5011997 D 405955 CDS YP_860021.1 117626698 4495382 5013366..5014184 1 NC_008563.1 phage-related; replication protein 5014184 4495382 APECO1_2041 Escherichia coli APEC O1 replication protein YP_860021.1 5013366 D 405955 CDS YP_860022.1 117626699 4495383 5014187..5014675 1 NC_008563.1 phage-related; hypothetical protein 5014675 yfdN 4495383 yfdN Escherichia coli APEC O1 hypothetical protein YP_860022.1 5014187 D 405955 CDS YP_860023.1 117626700 4495384 5014642..5015001 1 NC_008563.1 phage-related; hypothetical protein 5015001 4495384 APECO1_2039 Escherichia coli APEC O1 hypothetical protein YP_860023.1 5014642 D 405955 CDS YP_860024.1 117626701 4495385 5014998..5015387 1 NC_008563.1 Holliday junction resolvase; bacteriophage V crossover junction endodeoxyribonuclease 5015387 4495385 APECO1_2038 Escherichia coli APEC O1 bacteriophage V crossover junction endodeoxyribonuclease YP_860024.1 5014998 D 405955 CDS YP_860025.1 117626702 4495135 5015407..5015895 1 NC_008563.1 hypothetical protein 5015895 4495135 APECO1_2037 Escherichia coli APEC O1 hypothetical protein YP_860025.1 5015407 D 405955 CDS YP_860026.1 117626703 4495136 5016207..5017202 1 NC_008563.1 hypothetical protein 5017202 ydfA 4495136 ydfA Escherichia coli APEC O1 hypothetical protein YP_860026.1 5016207 D 405955 CDS YP_860027.1 117626704 4495137 5017174..5017968 1 NC_008563.1 lambdoid prophage Qin antitermination protein Q-like protein 5017968 4495137 APECO1_2035 Escherichia coli APEC O1 lambdoid prophage Qin antitermination protein Q-like protein YP_860027.1 5017174 D 405955 CDS YP_860028.1 117626705 4495138 5020085..5020636 1 NC_008563.1 hypothetical protein 5020636 4495138 APECO1_2034 Escherichia coli APEC O1 hypothetical protein YP_860028.1 5020085 D 405955 CDS YP_860029.1 117626706 4495139 5020958..5021491 1 NC_008563.1 Qin prophage; lysozyme 5021491 ydfQ 4495139 ydfQ Escherichia coli APEC O1 Qin prophage; lysozyme YP_860029.1 5020958 D 405955 CDS YP_860030.1 117626707 4495140 5021488..5021985 1 NC_008563.1 hypothetical protein 5021985 ydfP 4495140 ydfP Escherichia coli APEC O1 hypothetical protein YP_860030.1 5021488 D 405955 CDS YP_860031.1 117626708 4495141 5022794..5023063 1 NC_008563.1 hypothetical protein 5023063 4495141 APECO1_2031 Escherichia coli APEC O1 hypothetical protein YP_860031.1 5022794 D 405955 CDS YP_860032.1 117626709 4495142 5024196..5024474 1 NC_008563.1 hypothetical protein 5024474 4495142 APECO1_2030 Escherichia coli APEC O1 hypothetical protein YP_860032.1 5024196 D 405955 CDS YP_860033.1 117626710 4495143 5024464..5024955 1 NC_008563.1 phage-related; hypothetical protein 5024955 4495143 APECO1_2029 Escherichia coli APEC O1 hypothetical protein YP_860033.1 5024464 D 405955 CDS YP_860034.1 117626711 4495144 5024955..5027057 1 NC_008563.1 DNA packaging protein of prophage CP-933K 5027057 4495144 APECO1_2028 Escherichia coli APEC O1 DNA packaging protein of prophage CP-933K YP_860034.1 5024955 D 405955 CDS YP_860035.1 117626712 4495145 5027194..5028774 1 NC_008563.1 capsid protein 5028774 4495145 APECO1_2027 Escherichia coli APEC O1 capsid protein YP_860035.1 5027194 D 405955 CDS YP_860036.1 117626713 4495146 5028569..5030746 1 NC_008563.1 protease/scaffold protein 5030746 4495146 APECO1_2026 Escherichia coli APEC O1 protease/scaffold protein YP_860036.1 5028569 D 405955 CDS YP_860037.1 117626714 4495147 5030833..5031156 1 NC_008563.1 hypothetical protein 5031156 4495147 APECO1_2025 Escherichia coli APEC O1 hypothetical protein YP_860037.1 5030833 D 405955 CDS YP_860038.1 117626715 4495148 5031149..5031424 1 NC_008563.1 phage-related; hypothetical protein 5031424 4495148 APECO1_2024 Escherichia coli APEC O1 hypothetical protein YP_860038.1 5031149 D 405955 CDS YP_860039.1 117626716 4495149 5031436..5032014 1 NC_008563.1 tail component of prophage CP-933K 5032014 4495149 APECO1_2023 Escherichia coli APEC O1 tail component of prophage CP-933K YP_860039.1 5031436 D 405955 CDS YP_860040.1 117626717 4495150 5032348..5033166 1 NC_008563.1 tail component of prophage CP-933K 5033166 4495150 APECO1_2022 Escherichia coli APEC O1 tail component of prophage CP-933K YP_860040.1 5032348 D 405955 CDS YP_860041.1 117626718 4495151 5033215..5033613 1 NC_008563.1 tail component of prophage CP-933K 5033613 4495151 APECO1_2021 Escherichia coli APEC O1 tail component of prophage CP-933K YP_860041.1 5033215 D 405955 CDS YP_860042.1 117626719 4495152 5033622..5033951 1 NC_008563.1 minor tail protein 5033951 4495152 APECO1_2020 Escherichia coli APEC O1 minor tail protein YP_860042.1 5033622 D 405955 CDS YP_860043.1 117626720 4495153 5033914..5036988 1 NC_008563.1 tail component of prophage CP-933K 5036988 4495153 APECO1_2019 Escherichia coli APEC O1 tail component of prophage CP-933K YP_860043.1 5033914 D 405955 CDS YP_860044.1 117626721 4495154 5036988..5037317 1 NC_008563.1 minor tail protein 5037317 4495154 APECO1_2018 Escherichia coli APEC O1 minor tail protein YP_860044.1 5036988 D 405955 CDS YP_860045.1 117626722 4491959 5037327..5038025 1 NC_008563.1 minor tail protein 5038025 4491959 APECO1_2017 Escherichia coli APEC O1 minor tail protein YP_860045.1 5037327 D 405955 CDS YP_860046.1 117626723 4491960 5038030..5038773 1 NC_008563.1 tail fiber component K of prophage 5038773 4491960 APECO1_2016 Escherichia coli APEC O1 tail fiber component K of prophage YP_860046.1 5038030 D 405955 CDS YP_860047.1 117626724 4491961 5038671..5039318 1 NC_008563.1 phage-related; tail component of prophage CP-933K 5039318 4491961 APECO1_2015 Escherichia coli APEC O1 tail component of prophage CP-933K YP_860047.1 5038671 D 405955 CDS YP_860048.1 117626725 4491962 5039379..5042774 1 NC_008563.1 phage-related; tail component of prophage 5042774 4491962 APECO1_2014 Escherichia coli APEC O1 tail component of prophage YP_860048.1 5039379 D 405955 CDS YP_860049.1 117626726 4491963 5042842..5043441 1 NC_008563.1 outer membrane protein 5043441 4491963 APECO1_2013 Escherichia coli APEC O1 outer membrane protein YP_860049.1 5042842 D 405955 CDS YP_860050.1 117626727 4491964 5043500..5045884 1 NC_008563.1 phage-related; hypothetical protein 5045884 4491964 APECO1_2012 Escherichia coli APEC O1 hypothetical protein YP_860050.1 5043500 D 405955 CDS YP_860051.1 117626728 4491965 5045884..5046165 1 NC_008563.1 hypothetical protein 5046165 4491965 APECO1_2011 Escherichia coli APEC O1 hypothetical protein YP_860051.1 5045884 D 405955 CDS YP_860052.1 117626729 4491966 5046175..5046879 1 NC_008563.1 hypothetical protein 5046879 4491966 APECO1_2010 Escherichia coli APEC O1 hypothetical protein YP_860052.1 5046175 D 405955 CDS YP_860053.1 117626730 4491967 complement(5046970..5047323) 1 NC_008563.1 hypothetical protein 5047323 4491967 APECO1_2009 Escherichia coli APEC O1 hypothetical protein YP_860053.1 5046970 R 405955 CDS YP_860054.1 117626731 4491968 complement(5047411..5048001) 1 NC_008563.1 recombinase; Rac prophage; site-specific recombinase 5048001 pinR 4491968 pinR Escherichia coli APEC O1 Rac prophage; site-specific recombinase YP_860054.1 5047411 R 405955 CDS YP_860055.1 117626732 4491969 complement(5048318..5048584) 1 NC_008563.1 hypothetical protein 5048584 ydfK 4491969 ydfK Escherichia coli APEC O1 hypothetical protein YP_860055.1 5048318 R 405955 CDS YP_860056.1 117626733 4491970 5049628..5051214 1 NC_008563.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5051214 prfC 4491970 prfC Escherichia coli APEC O1 peptide chain release factor 3 YP_860056.1 5049628 D 405955 CDS YP_860057.1 117626734 4491971 5051607..5052212 1 NC_008563.1 hypothetical protein 5052212 4491971 APECO1_2005 Escherichia coli APEC O1 hypothetical protein YP_860057.1 5051607 D 405955 CDS YP_860058.1 117626735 4491972 5052622..5053695 1 NC_008563.1 hypothetical protein 5053695 yjjU 4491972 yjjU Escherichia coli APEC O1 hypothetical protein YP_860058.1 5052622 D 405955 CDS YP_860059.1 117626736 4491973 5053836..5054471 1 NC_008563.1 deoxyribonuclease YjjV 5054471 yjjV 4491973 yjjV Escherichia coli APEC O1 deoxyribonuclease YjjV YP_860059.1 5053836 D 405955 CDS YP_860060.1 117626737 4491974 complement(5054688..5055551) 1 NC_008563.1 hypothetical protein 5055551 4491974 APECO1_2002 Escherichia coli APEC O1 hypothetical protein YP_860060.1 5054688 R 405955 CDS YP_860061.1 117626738 4491975 complement(5055523..5057073) 1 NC_008563.1 hypothetical protein 5057073 yjjI 4491975 yjjI Escherichia coli APEC O1 hypothetical protein YP_860061.1 5055523 R 405955 CDS YP_860062.1 117626739 4491976 5057331..5058110 1 NC_008563.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5058110 deoC 4491976 deoC Escherichia coli APEC O1 deoxyribose-phosphate aldolase YP_860062.1 5057331 D 405955 CDS YP_860063.1 117626740 4491977 5058137..5059510 1 NC_008563.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5059510 deoA 4491977 deoA Escherichia coli APEC O1 thymidine phosphorylase YP_860063.1 5058137 D 405955 CDS YP_860064.1 117626741 4494736 5059562..5060785 1 NC_008563.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5060785 deoB 4494736 deoB Escherichia coli APEC O1 phosphopentomutase YP_860064.1 5059562 D 405955 CDS YP_860065.1 117626742 4494737 5060785..5061561 1 NC_008563.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5061561 deoD 4494737 deoD Escherichia coli APEC O1 purine nucleoside phosphorylase YP_860065.1 5060785 D 405955 CDS YP_860066.1 117626743 4494738 5061728..5063059 1 NC_008563.1 hypothetical protein 5063059 yjjJ 4494738 yjjJ Escherichia coli APEC O1 hypothetical protein YP_860066.1 5061728 D 405955 CDS YP_860067.1 117626744 4494739 complement(5063060..5064076) 1 NC_008563.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 5064076 lplA 4494739 lplA Escherichia coli APEC O1 lipoate-protein ligase A YP_860067.1 5063060 R 405955 CDS YP_860068.1 117626745 4494740 complement(5064104..5064748) 1 NC_008563.1 hypothetical protein 5064748 smp 4494740 smp Escherichia coli APEC O1 hypothetical protein YP_860068.1 5064104 R 405955 CDS YP_860069.2 229775945 4494741 5064854..5065822 1 NC_008563.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5065822 serB 4494741 serB Escherichia coli APEC O1 phosphoserine phosphatase YP_860069.2 5064854 D 405955 CDS YP_860070.1 117626747 4494742 5065871..5067253 1 NC_008563.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5067253 radA 4494742 radA Escherichia coli APEC O1 DNA repair protein RadA YP_860070.1 5065871 D 405955 CDS YP_860071.1 117626748 4494743 5067253..5068506 1 NC_008563.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5068506 nadR 4494743 nadR Escherichia coli APEC O1 nicotinamide-nucleotide adenylyltransferase YP_860071.1 5067253 D 405955 CDS YP_860072.1 117626749 4494744 5068520..5068930 1 NC_008563.1 hypothetical protein 5068930 4494744 APECO1_1990 Escherichia coli APEC O1 hypothetical protein YP_860072.1 5068520 D 405955 CDS YP_860073.1 117626750 4494745 5068932..5069216 1 NC_008563.1 regulatory protein 5069216 4494745 APECO1_1989 Escherichia coli APEC O1 regulatory protein YP_860073.1 5068932 D 405955 CDS YP_860074.1 117626751 4494746 complement(5069272..5070939) 1 NC_008563.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 5070939 yjjK 4494746 yjjK Escherichia coli APEC O1 ABC transporter ATP-binding protein YP_860074.1 5069272 R 405955 CDS YP_860075.1 117626752 4494747 5071146..5073083 1 NC_008563.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5073083 slt 4494747 slt Escherichia coli APEC O1 lytic murein transglycosylase YP_860075.1 5071146 D 405955 CDS YP_860076.1 117626753 4494748 5073173..5073499 1 NC_008563.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5073499 trpR 4494748 trpR Escherichia coli APEC O1 Trp operon repressor YP_860076.1 5073173 D 405955 CDS YP_860077.1 117626754 4494749 complement(5073572..5074108) 1 NC_008563.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 5074108 yjjX 4494749 yjjX Escherichia coli APEC O1 NTPase YP_860077.1 5073572 R 405955 CDS YP_860078.1 117626755 4494750 5074151..5074798 1 NC_008563.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5074798 gpmB 4494750 gpmB Escherichia coli APEC O1 phosphoglycerate mutase YP_860078.1 5074151 D 405955 CDS YP_860079.1 117626756 4494751 complement(5074795..5075664) 1 NC_008563.1 right origin-binding protein 5075664 rob 4494751 rob Escherichia coli APEC O1 right origin-binding protein YP_860079.1 5074795 R 405955 CDS YP_860080.1 117626757 4494752 5075875..5076348 1 NC_008563.1 hypothetical protein 5076348 creA 4494752 creA Escherichia coli APEC O1 hypothetical protein YP_860080.1 5075875 D 405955 CDS YP_860081.1 117626758 4494753 5076361..5077050 1 NC_008563.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5077050 creB 4494753 creB Escherichia coli APEC O1 DNA-binding response regulator CreB YP_860081.1 5076361 D 405955 CDS YP_860082.1 117626759 4494754 5077050..5078474 1 NC_008563.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5078474 creC 4494754 creC Escherichia coli APEC O1 sensory histidine kinase CreC YP_860082.1 5077050 D 405955 CDS YP_860083.1 117626760 4494755 5078532..5079884 1 NC_008563.1 hypothetical protein 5079884 creD 4494755 creD Escherichia coli APEC O1 hypothetical protein YP_860083.1 5078532 D 405955 CDS YP_860084.1 117626761 4495365 complement(5079944..5080660) 1 NC_008563.1 two-component response regulator 5080660 arcA 4495365 arcA Escherichia coli APEC O1 two-component response regulator YP_860084.1 5079944 R 405955 CDS YP_860085.1 117626762 4495366 5081296..5081982 1 NC_008563.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5081982 lasT 4495366 lasT Escherichia coli APEC O1 RNA methyltransferase YP_860085.1 5081296 D 405955 CDS YP_001481156.1 157418084 5616509 27..239 1 NC_009837.1 IS1 InsA protein; similar to CAA11401; hypothetical protein 239 insA 5616509 insA Escherichia coli APEC O1 hypothetical protein YP_001481156.1 27 D 405955 CDS YP_001481157.1 157418085 5616510 250..753 1 NC_009837.1 IS1 InsB protein; identified by match to protein family HMM PF03400; similar to AAK09058; hypothetical protein 753 insB 5616510 insB Escherichia coli APEC O1 hypothetical protein YP_001481157.1 250 D 405955 CDS YP_001481158.2 229776985 5616511 1053..2219 1 NC_009837.1 stabilization of plasmid protein A; identified by match to protein family HMM PF01656; similar to NP_866033; plasmid-partitioning protein SopA 2219 sopA 5616511 sopA Escherichia coli APEC O1 plasmid-partitioning protein SopA YP_001481158.2 1053 D 405955 CDS YP_001481159.1 157418087 5616512 2219..3190 1 NC_009837.1 stabilization of plasmid protein B; identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; SopB; plasmid-partitioning protein 3190 sopB 5616512 sopB Escherichia coli APEC O1 plasmid-partitioning protein YP_001481159.1 2219 D 405955 CDS YP_001481160.1 157418088 5616513 3775..4035 1 NC_009837.1 hypothetical protein 4035 5616513 APECO1_O1CoBM5 Escherichia coli APEC O1 hypothetical protein YP_001481160.1 3775 D 405955 CDS YP_001481161.1 157418089 5616514 complement(4146..5264) 1 NC_009837.1 transposase for IS186; similar to AAC75453; identified by match to protein family HMM PF01609; InsL 5264 insL 5616514 insL Escherichia coli APEC O1 InsL YP_001481161.1 4146 R 405955 CDS YP_001481162.1 157418090 5616515 5311..5826 1 NC_009837.1 putative antirestriction protein; similar to AAO49634; identified by match to protein family HMM PF03230; hypothetical protein 5826 5616515 APECO1_O1CoBM7 Escherichia coli APEC O1 hypothetical protein YP_001481162.1 5311 D 405955 CDS YP_001481163.1 157418091 5616516 5917..6288 1 NC_009837.1 similar to BAA84887; hypothetical protein 6288 5616516 APECO1_O1CoBM8 Escherichia coli APEC O1 hypothetical protein YP_001481163.1 5917 D 405955 CDS YP_001481164.1 157418092 5616517 complement(6624..6968) 1 NC_009837.1 similar to AAO49636; hypothetical protein 6968 5616517 APECO1_O1CoBM9 Escherichia coli APEC O1 hypothetical protein YP_001481164.1 6624 R 405955 CDS YP_001481165.1 157418093 5616518 complement(7482..7742) 1 NC_009837.1 similar to YP_053128; hypothetical protein 7742 5616518 APECO1_O1CoBM10 Escherichia coli APEC O1 hypothetical protein YP_001481165.1 7482 R 405955 CDS YP_001481166.1 157418094 5616519 7746..9107 1 NC_009837.1 putative hydrolase; similar to YP_194824; hypothetical protein 9107 5616519 APECO1_O1CoBM11 Escherichia coli APEC O1 hypothetical protein YP_001481166.1 7746 D 405955 CDS YP_001481167.1 157418095 5616520 9155..9718 1 NC_009837.1 similar to ZP00719055; adenine-specific DNA methylase 9718 5616520 APECO1_O1CoBM12 Escherichia coli APEC O1 adenine-specific DNA methylase YP_001481167.1 9155 D 405955 CDS YP_001481168.1 157418096 5616521 10133..10381 1 NC_009837.1 similar to AAO49639; hypothetical protein 10381 5616521 APECO1_O1CoBM13 Escherichia coli APEC O1 hypothetical protein YP_001481168.1 10133 D 405955 CDS YP_001481169.1 157418097 5616522 10570..11136 1 NC_009837.1 single-stranded binding protein; similar to AAO49641; identified by match to protein family HMM PF00436; single-stranded DNA-binding protein 11136 ssb 5616522 ssb Escherichia coli APEC O1 single-stranded DNA-binding protein YP_001481169.1 10570 D 405955 CDS YP_001481170.1 157418098 5616523 11165..11425 1 NC_009837.1 similar to AAR05684; identified by match to protein family HMM PF06006; hypothetical protein 11425 5616523 APECO1_O1CoBM15 Escherichia coli APEC O1 hypothetical protein YP_001481170.1 11165 D 405955 CDS YP_001481171.1 157418099 5616524 11478..13442 1 NC_009837.1 putative transcriptional regulator; similar to AAR05685; hypothetical protein 13442 5616524 APECO1_O1CoBM16 Escherichia coli APEC O1 hypothetical protein YP_001481171.1 11478 D 405955 CDS YP_001481172.1 157418100 5616525 13494..13931 1 NC_009837.1 plasmid SOS inhibition protein; similar to AAR25067; identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 13931 psiB 5616525 psiB Escherichia coli APEC O1 plasmid SOS inhibition protein B YP_001481172.1 13494 D 405955 CDS YP_001481173.1 157418101 5616526 13928..14647 1 NC_009837.1 plasmid SOS inhibition protein; similar to AAO49644; identified by match to protein family HMM PF06952; PsiA; plasmid SOS inhibition protein A 14647 psiA 5616526 psiA Escherichia coli APEC O1 plasmid SOS inhibition protein A YP_001481173.1 13928 D 405955 CDS YP_001481174.1 157418102 5616527 complement(14659..14883) 1 NC_009837.1 suppression of killing; similar to SOK_ECOLI; hypothetical protein 14883 sok 5616527 sok Escherichia coli APEC O1 hypothetical protein YP_001481174.1 14659 R 405955 CDS YP_001481175.1 157418103 5616528 14869..15081 1 NC_009837.1 modulator protein; similar to AAO49646; Mok; similar to F leading maintenance protein C; modulator of post-segregation killing protein 15081 mok 5616528 mok Escherichia coli APEC O1 modulator of post-segregation killing protein YP_001481175.1 14869 D 405955 CDS YP_001481176.1 157418104 5616529 15305..15535 1 NC_009837.1 hypothetical protein 15535 5616529 APECO1_O1CoBM21 Escherichia coli APEC O1 hypothetical protein YP_001481176.1 15305 D 405955 CDS YP_001481177.1 157418105 5616530 15532..15774 1 NC_009837.1 similar to AAR05690; hypothetical protein 15774 5616530 APECO1_O1CoBM22 Escherichia coli APEC O1 hypothetical protein YP_001481177.1 15532 D 405955 CDS YP_001481178.1 157418106 5616531 16007..16294 1 NC_009837.1 similar to AAO49511; hypothetical protein 16294 5616531 APECO1_O1CoBM23 Escherichia coli APEC O1 hypothetical protein YP_001481178.1 16007 D 405955 CDS YP_001481179.1 157418107 5616532 16301..17236 1 NC_009837.1 similar to YP_190149; identified by match to protein family HMM PF06067; hypothetical protein 17236 5616532 APECO1_O1CoBM24 Escherichia coli APEC O1 hypothetical protein YP_001481179.1 16301 D 405955 CDS YP_001481180.1 157418108 5616533 complement(17533..18135) 1 NC_009837.1 similar to YP_190148; identified by match to protein family HMM PF01464; lytic transglycosylase 18135 5616533 APECO1_O1CoBM25 Escherichia coli APEC O1 lytic transglycosylase YP_001481180.1 17533 R 405955 CDS YP_001481181.1 157418109 5616534 18456..18839 1 NC_009837.1 conjugal transfer protein; similar to AAO49514; identified by match to protein family HMM PF05261; conjugal transfer protein TraM 18839 traM 5616534 traM Escherichia coli APEC O1 conjugal transfer protein TraM YP_001481181.1 18456 D 405955 CDS YP_001481182.1 157418110 5616535 19026..19715 1 NC_009837.1 positive regulator of conjugative transfer; similar to AAO49515; conjugal transfer transcriptional regulator TraJ 19715 traJ 5616535 traJ Escherichia coli APEC O1 conjugal transfer transcriptional regulator TraJ YP_001481182.1 19026 D 405955 CDS YP_001481183.1 157418111 5616536 19808..20209 1 NC_009837.1 conjugal transfer protein; similar to AAO49516; identified by match to protein family HMM PF05509; conjugal transfer protein TraY 20209 traY 5616536 traY Escherichia coli APEC O1 conjugal transfer protein TraY YP_001481183.1 19808 D 405955 CDS YP_001481184.1 157418112 5616537 20242..20607 1 NC_009837.1 pilin protein; similar to AAO49517; identified by match to protein family HMM PF05513; conjugal transfer pilin subunit TraA 20607 traA 5616537 traA Escherichia coli APEC O1 conjugal transfer pilin subunit TraA YP_001481184.1 20242 D 405955 CDS YP_001481185.1 157418113 5616538 20622..20933 1 NC_009837.1 conjugal transfer protein; similar to AAO49518; identified by match to protein family HMM PF07178; conjugal transfer pilus assembly protein TraL 20933 traL 5616538 traL Escherichia coli APEC O1 conjugal transfer pilus assembly protein TraL YP_001481185.1 20622 D 405955 CDS YP_001481186.1 157418114 5616539 20955..21521 1 NC_009837.1 conjugal transfer protein; similar to AAO49519; identified by match to protein family HMM PF05309; conjugal transfer pilus assembly protein TraE 21521 traE 5616539 traE Escherichia coli APEC O1 conjugal transfer pilus assembly protein TraE YP_001481186.1 20955 D 405955 CDS YP_001481187.1 157418115 5616540 21508..22236 1 NC_009837.1 conjugal transfer protein; similar to AAO49520; identified by match to protein family HMM PF06586; conjugal transfer protein TraK 22236 traK 5616540 traK Escherichia coli APEC O1 conjugal transfer protein TraK YP_001481187.1 21508 D 405955 CDS YP_001481188.1 157418116 5616541 22236..23663 1 NC_009837.1 conjugal transfer protein; similar to AAO49521; identified by match to protein family HMM PF06447; conjugal transfer pilus assembly protein TraB 23663 traB 5616541 traB Escherichia coli APEC O1 conjugal transfer pilus assembly protein TraB YP_001481188.1 22236 D 405955 CDS YP_001481189.1 157418117 5616542 23653..24243 1 NC_009837.1 conjugal transfer protein; similar to AAO49522; identified by match to protein family HMM PF07296; conjugal transfer protein TraP 24243 traP 5616542 traP Escherichia coli APEC O1 conjugal transfer protein TraP YP_001481189.1 23653 D 405955 CDS YP_001481190.1 157418118 5616543 24197..24427 1 NC_009837.1 conjugal transfer protein; similar to AAO49523; conjugal transfer protein TrbD 24427 trbD 5616543 trbD Escherichia coli APEC O1 conjugal transfer protein TrbD YP_001481190.1 24197 D 405955 CDS YP_001481191.1 157418119 5616544 24439..24690 1 NC_009837.1 conjugal transfer protein; similar to AAO49524; conjugal transfer protein TrbG 24690 trbG 5616544 trbG Escherichia coli APEC O1 conjugal transfer protein TrbG YP_001481191.1 24439 D 405955 CDS YP_001481192.1 157418120 5616545 24687..25202 1 NC_009837.1 conjugal transfer protein; similar to AAO49525; conjugal transfer protein TraV 25202 traV 5616545 traV Escherichia coli APEC O1 conjugal transfer protein TraV YP_001481192.1 24687 D 405955 CDS YP_001481193.1 157418121 5616546 25337..25558 1 NC_009837.1 conjugal transfer protein; similar to AAO49526; conjugal transfer protein TraR 25558 traR 5616546 traR Escherichia coli APEC O1 conjugal transfer protein TraR YP_001481193.1 25337 D 405955 CDS YP_001481194.1 157418122 5616547 25718..28345 1 NC_009837.1 pilus assembly and synthesis; similar to AAO49527; similar to VirB4; conjugal transfer ATP-binding protein TraC 28345 traC 5616547 traC Escherichia coli APEC O1 conjugal transfer ATP-binding protein TraC YP_001481194.1 25718 D 405955 CDS YP_001481195.1 157418123 5616548 28342..28728 1 NC_009837.1 conjugal transfer protein; similar to AAO49648; conjugal transfer protein TrbI 28728 trbI 5616548 trbI Escherichia coli APEC O1 conjugal transfer protein TrbI YP_001481195.1 28342 D 405955 CDS YP_001481196.2 229776984 5616549 28725..29357 1 NC_009837.1 conjugal transfer protein; similar to AAO49528; conjugal transfer pilus assembly protein TraW 29357 traW 5616549 traW Escherichia coli APEC O1 conjugal transfer pilus assembly protein TraW YP_001481196.2 28725 D 405955 CDS YP_001481197.1 157418125 5616550 29354..30346 1 NC_009837.1 conjugal transfer protein; similar to AAO49529; identified by match to protein family HMM PF06834; conjugal transfer pilus assembly protein TraU 30346 traU 5616550 traU Escherichia coli APEC O1 conjugal transfer pilus assembly protein TraU YP_001481197.1 29354 D 405955 CDS YP_001481198.1 157418126 5616551 30352..30993 1 NC_009837.1 periplasmic protein; similar to AAC44205; conjugal transfer pilus assembly protein TrbC 30993 trbC 5616551 trbC Escherichia coli APEC O1 conjugal transfer pilus assembly protein TrbC YP_001481198.1 30352 D 405955 CDS YP_001481199.1 157418127 5616552 30990..32798 1 NC_009837.1 mating pair stabilization protein; similar to AAO49531; identified by match to protein family HMM PF06986; TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 32798 traN 5616552 traN Escherichia coli APEC O1 conjugal transfer mating pair stabilization protein TraN YP_001481199.1 30990 D 405955 CDS YP_001481200.1 157418128 5616553 32822..33082 1 NC_009837.1 conjugal transfer protein; similar to AAO49532; conjugal transfer protein TrbE 33082 trbE 5616553 trbE Escherichia coli APEC O1 conjugal transfer protein TrbE YP_001481200.1 32822 D 405955 CDS YP_001481201.1 157418129 5616554 33045..33818 1 NC_009837.1 conjugal transfer protein; similar to AAO49533; type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal pilus assembly protein TraF 33818 traF 5616554 traF Escherichia coli APEC O1 conjugal pilus assembly protein TraF YP_001481201.1 33045 D 405955 CDS YP_001481202.1 157418130 5616555 33834..34181 1 NC_009837.1 conjugal transfer protein; similar to AAO49534; conjugal transfer protein TrbA 34181 trbA 5616555 trbA Escherichia coli APEC O1 conjugal transfer protein TrbA YP_001481202.1 33834 D 405955 CDS YP_001481203.1 157418131 5616556 complement(34183..34458) 1 NC_009837.1 conserved hypothetical protein; similar to AAC44178; hypothetical protein 34458 artA 5616556 artA Escherichia coli APEC O1 hypothetical protein YP_001481203.1 34183 R 405955 CDS YP_001481204.1 157418132 5616557 34584..34820 1 NC_009837.1 pilin chaperone protein; similar to AAO49536; conjugal transfer pilin chaperone TraQ 34820 traQ 5616557 traQ Escherichia coli APEC O1 conjugal transfer pilin chaperone TraQ YP_001481204.1 34584 D 405955 CDS YP_001481205.1 157418133 5616558 34807..35352 1 NC_009837.1 conjugal transfer protein; similar to AAR25104; conjugal transfer protein TrbB 35352 trbB 5616558 trbB Escherichia coli APEC O1 conjugal transfer protein TrbB YP_001481205.1 34807 D 405955 CDS YP_001481206.1 157418134 5616559 35282..35623 1 NC_009837.1 conjugal transfer protein; similar to AAO49538; conjugal transfer protein TrbJ 35623 trbJ 5616559 trbJ Escherichia coli APEC O1 conjugal transfer protein TrbJ YP_001481206.1 35282 D 405955 CDS YP_001481207.1 157418135 5616560 complement(35663..35968) 1 NC_009837.1 conjugal transfer protein; similar to AAO49539; hypothetical protein 35968 trbF 5616560 trbF Escherichia coli APEC O1 hypothetical protein YP_001481207.1 35663 R 405955 CDS YP_001481208.1 157418136 5616561 35989..40185 1 NC_009837.1 pilus assembly protein; similar to YP_190118; identified by match to protein family HMM PF06122; hypothetical protein 40185 traG 5616561 traG Escherichia coli APEC O1 hypothetical protein YP_001481208.1 35989 D 405955 CDS YP_001481209.1 157418137 5616562 40182..40691 1 NC_009837.1 surface exclusion protein; similar to AAO49542; conjugal transfer entry exclusion protein TraS 40691 traS 5616562 traS Escherichia coli APEC O1 conjugal transfer entry exclusion protein TraS YP_001481209.1 40182 D 405955 CDS YP_001481210.1 157418138 5616563 40705..41436 1 NC_009837.1 surface exclusion and complement resistance protein; similar to AAT85681; identified by match to protein family HMM PF05818; conjugal transfer surface exclusion protein TraT 41436 traT 5616563 traT Escherichia coli APEC O1 conjugal transfer surface exclusion protein TraT YP_001481210.1 40705 D 405955 CDS YP_001481211.1 157418139 5616566 41689..43842 1 NC_009837.1 coupling protein; similar to AAC44181; type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD 43842 traD 5616566 traD Escherichia coli APEC O1 conjugal transfer protein TraD YP_001481211.1 41689 D 405955 CDS YP_001481212.1 157418140 5616564 43842..44561 1 NC_009837.1 conserved hypothetical protein; similar to AAP79033; identified by match to protein family HMM PF01850; TrbH 44561 trbH 5616566 trbH Escherichia coli APEC O1 TrbH YP_001481212.1 43842 D 405955 CDS YP_001481213.1 157418141 5616565 44537..49828 1 NC_009837.1 DNA helicase I; similar to YP_190115; identified by match to protein family HMM PF07057; cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer nickase/helicase TraI 49828 traI 5616565 traI Escherichia coli APEC O1 conjugal transfer nickase/helicase TraI YP_001481213.1 44537 D 405955 CDS YP_001481214.1 157418142 5616567 49848..50594 1 NC_009837.1 F pilin acetylase; similar to YP_190114; conjugal transfer pilus acetylation protein TraX 50594 traX 5616567 traX Escherichia coli APEC O1 conjugal transfer pilus acetylation protein TraX YP_001481214.1 49848 D 405955 CDS YP_001481215.1 157418143 5616568 50653..51513 1 NC_009837.1 putative hydrolase, alpha/beta fold family; similar to YP_190113; identified by match to protein family HMM PF00561; hypothetical protein 51513 5616568 APECO1_O1CoBM60 Escherichia coli APEC O1 hypothetical protein YP_001481215.1 50653 D 405955 CDS YP_001481216.1 157418144 5616569 51616..52176 1 NC_009837.1 fertility inhibition protein; similar to YP_313451; identified by match to protein family HMM PF05286; conjugal transfer fertility inhibition protein FinO 52176 finO 5616569 finO Escherichia coli APEC O1 conjugal transfer fertility inhibition protein FinO YP_001481216.1 51616 D 405955 CDS YP_001481217.1 157418145 5616570 52312..52524 1 NC_009837.1 similar to YP_313453; hypothetical protein 52524 5616570 APECO1_O1CoBM62 Escherichia coli APEC O1 hypothetical protein YP_001481217.1 52312 D 405955 CDS YP_001481218.1 157418146 5616571 53043..53354 1 NC_009837.1 modulator of post-segregational killing; similar to BAA97874; hypothetical protein 53354 srnB 5616571 srnB Escherichia coli APEC O1 hypothetical protein YP_001481218.1 53043 D 405955 CDS YP_001481219.1 157418147 5616572 53638..53895 1 NC_009837.1 replication regulatory protein; similar to BAA97876; replication protein 53895 repA2 5616572 repA2 Escherichia coli APEC O1 replication protein YP_001481219.1 53638 D 405955 CDS YP_001481220.1 157418148 5616573 complement(53912..54214) 1 NC_009837.1 replication protein; similar to CAA23641; RepA3 54214 repA3 5616573 repA3 Escherichia coli APEC O1 RepA3 YP_001481220.1 53912 R 405955 CDS YP_001481221.1 157418149 5616574 54182..54676 1 NC_009837.1 repFIC initiation protein; similar to AAA99008; hypothetical protein 54676 repA 5616574 repA Escherichia coli APEC O1 hypothetical protein YP_001481221.1 54182 D 405955 CDS YP_001481222.2 229776983 5616575 54669..55526 1 NC_009837.1 replication protein; similar to AAO49555; identified by match to protein family HMM PF02387; IncFII replicon family; RepA; replication protein 55526 repA1 5616575 repA1 Escherichia coli APEC O1 replication protein YP_001481222.2 54669 D 405955 CDS YP_001481223.1 157418151 5616576 complement(56095..56373) 1 NC_009837.1 replication protein; similar to NP_052991; hypothetical protein 56373 repA4 5616576 repA4 Escherichia coli APEC O1 hypothetical protein YP_001481223.1 56095 R 405955 CDS YP_001481224.1 157418152 5616577 56435..56740 1 NC_009837.1 antitoxin of toxin stability system; similar to YP_313640; identified by match to protein family HMM PF02604; hypothetical protein 56740 5616577 APECO1_O1CoBM69 Escherichia coli APEC O1 hypothetical protein YP_001481224.1 56435 D 405955 CDS YP_001481225.1 157418153 5616578 56737..57024 1 NC_009837.1 cytotoxic translational repressor; similar to YP_313641; identified by match to protein family HMM PF05016; hypothetical protein 57024 relE 5616578 relE Escherichia coli APEC O1 hypothetical protein YP_001481225.1 56737 D 405955 CDS YP_001481226.1 157418154 5616579 complement(57293..58183) 1 NC_009837.1 transposase for IS629; similar to CAD88882; identified by match to protein family HMM PF00665; hypothetical protein 58183 5616579 APECO1_O1CoBM71 Escherichia coli APEC O1 hypothetical protein YP_001481226.1 57293 R 405955 CDS YP_001481227.1 157418155 5616580 complement(58180..58506) 1 NC_009837.1 similar to NP_288505; hypothetical protein 58506 5616580 APECO1_O1CoBM72 Escherichia coli APEC O1 hypothetical protein YP_001481227.1 58180 R 405955 CDS YP_001481228.1 157418156 5616581 58775..62908 1 NC_009837.1 temperature sensitive hemagglutinin; similar to AAA24698; identified by match to protein family HMM PF02395; Tsh 62908 tsh 5616581 tsh Escherichia coli APEC O1 Tsh YP_001481228.1 58775 D 405955 CDS YP_001481229.1 157418157 5616582 62991..63203 1 NC_009837.1 transposase fro IS1; similar to CAE55752; hypothetical protein 63203 insA 5616582 insA Escherichia coli APEC O1 hypothetical protein YP_001481229.1 62991 D 405955 CDS YP_001481230.1 157418158 5616583 63214..63702 1 NC_009837.1 IS1 InsB protein; similar to NP_863025; identified by match to protein family HMM PF03400; hypothetical protein 63702 insB 5616583 insB Escherichia coli APEC O1 hypothetical protein YP_001481230.1 63214 D 405955 CDS YP_001481231.1 157418159 5616584 complement(63773..64522) 1 NC_009837.1 similar to DQ269483; identified by match to protein family HMM PF01695; ISEc12 putative ATP-binding protein 64522 5616584 APECO1_O1CoBM76 Escherichia coli APEC O1 ISEc12 putative ATP-binding protein YP_001481231.1 63773 R 405955 CDS YP_001481232.1 157418160 5616585 complement(64534..66075) 1 NC_009837.1 similar to DQ269483; identified by match to protein family HMM PF00665; putative transposase for ISEc12 66075 5616585 APECO1_O1CoBM77 Escherichia coli APEC O1 putative transposase for ISEc12 YP_001481232.1 64534 R 405955 CDS YP_001481233.1 157418161 5616586 complement(66313..67350) 1 NC_009837.1 similar to YP_194858; hypothetical protein 67350 5616586 APECO1_O1CoBM78 Escherichia coli APEC O1 hypothetical protein YP_001481233.1 66313 R 405955 CDS YP_001481234.1 157418162 5616587 complement(67335..68900) 1 NC_009837.1 similar to YP_194859; hypothetical protein 68900 5616587 APECO1_O1CoBM79 Escherichia coli APEC O1 hypothetical protein YP_001481234.1 67335 R 405955 CDS YP_001481235.1 157418163 5616588 68894..69649 1 NC_009837.1 virulence-associated gene D; similar to YP_194860; identified by match to protein family HMM PF01850; hypothetical protein 69649 vagD 5616588 vagD Escherichia coli APEC O1 hypothetical protein YP_001481235.1 68894 D 405955 CDS YP_001481236.1 157418164 5616589 69950..70432 1 NC_009837.1 putative acetyltransferase; similar to NP_761263; identified by match to protein family HMM PF04014; hypothetical protein 70432 5616589 APECO1_O1CoBM81 Escherichia coli APEC O1 hypothetical protein YP_001481236.1 69950 D 405955 CDS YP_001481237.1 157418165 5616590 complement(70464..71996) 1 NC_009837.1 putative dimethylaniline monoxygenase; similar to CAA11511; identified by match to protein family HMM PF00743; hypothetical protein 71996 5616590 APECO1_O1CoBM82 Escherichia coli APEC O1 hypothetical protein YP_001481237.1 70464 R 405955 CDS YP_001481238.1 157418166 5616591 71817..72305 1 NC_009837.1 similar to NP_875585; hypothetical protein 72305 5616591 APECO1_O1CoBM83 Escherichia coli APEC O1 hypothetical protein YP_001481238.1 71817 D 405955 CDS YP_001481239.1 157418167 5616592 complement(72264..73283) 1 NC_009837.1 putative oxidoreductase; similar to CAA11512; identified by match to protein family HMM PF01408; hypothetical protein 73283 5616592 APECO1_O1CoBM84 Escherichia coli APEC O1 hypothetical protein YP_001481239.1 72264 R 405955 CDS YP_001481240.1 157418168 5616593 complement(73283..74203) 1 NC_009837.1 putative hydrolase; similar to AAK03131; identified by match to protein family HMM TIGR01484; hypothetical protein 74203 5616593 APECO1_O1CoBM85 Escherichia coli APEC O1 hypothetical protein YP_001481240.1 73283 R 405955 CDS YP_001481241.1 157418169 5616594 complement(74094..75332) 1 NC_009837.1 putative aminotransferase; similar to NP_388936; identified by match to protein family HMM PF01041; hypothetical protein 75332 5616594 APECO1_O1CoBM86 Escherichia coli APEC O1 hypothetical protein YP_001481241.1 74094 R 405955 CDS YP_001481242.1 157418170 5616595 75872..77005 1 NC_009837.1 similar to NP_943348; hypothetical protein 77005 5616595 APECO1_O1CoBM87 Escherichia coli APEC O1 hypothetical protein YP_001481242.1 75872 D 405955 CDS YP_001481243.1 157418171 5616596 77025..77309 1 NC_009837.1 conserved hypothetical protein; similar to NP_943347; hypothetical protein 77309 korC 5616596 korC Escherichia coli APEC O1 hypothetical protein YP_001481243.1 77025 D 405955 CDS YP_001481244.1 157418172 5616597 complement(77306..77503) 1 NC_009837.1 similar to NP_943346; hypothetical protein 77503 5616597 APECO1_O1CoBM89 Escherichia coli APEC O1 hypothetical protein YP_001481244.1 77306 R 405955 CDS YP_001481245.1 157418173 5616598 complement(77552..77761) 1 NC_009837.1 hypothetical protein 77761 5616598 APECO1_O1CoBM90 Escherichia coli APEC O1 hypothetical protein YP_001481245.1 77552 R 405955 CDS YP_001481246.1 157418174 5616599 78075..78476 1 NC_009837.1 similar to NP_755452; identified by match to protein family HMM PF01527; hypothetical protein 78476 5616599 APECO1_O1CoBM91 Escherichia coli APEC O1 hypothetical protein YP_001481246.1 78075 D 405955 CDS YP_001481247.1 157418175 5616600 78473..78820 1 NC_009837.1 putative transposase of ISEc8; identified by match to protein family HMM PF05717; hypothetical protein 78820 5616600 APECO1_O1CoBM92 Escherichia coli APEC O1 hypothetical protein YP_001481247.1 78473 D 405955 CDS YP_001481248.1 157418176 5616601 78870..80408 1 NC_009837.1 putative transposase; identified by match to protein family HMM PF03050; hypothetical protein 80408 5616601 APECO1_O1CoBM93 Escherichia coli APEC O1 hypothetical protein YP_001481248.1 78870 D 405955 CDS YP_001481249.1 157418177 5616602 80524..80802 1 NC_009837.1 similar to NP_085375; identified by match to protein family HMM PF01527; hypothetical protein 80802 5616602 APECO1_O1CoBM94 Escherichia coli APEC O1 hypothetical protein YP_001481249.1 80524 D 405955 CDS YP_001481250.1 157418178 5616603 80760..81665 1 NC_009837.1 IS2 transposase; similar to NP_418693; identified by match to protein family HMM PF00665; IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 81665 5616603 APECO1_O1CoBM95 Escherichia coli APEC O1 insertion element IS2 transposase InsD YP_001481250.1 80760 D 405955 CDS YP_001481251.1 157418179 5616604 81930..85427 1 NC_009837.1 putative adhesin; similar to BAB33785; identified by match to protein family HMM PF03212; match to protein family HMM PF03797; hypothetical protein 85427 5616604 APECO1_O1CoBM96 Escherichia coli APEC O1 hypothetical protein YP_001481251.1 81930 D 405955 CDS YP_001481252.1 157418180 5616605 85574..85900 1 NC_009837.1 similar to NP_288505; hypothetical protein 85900 5616605 APECO1_O1CoBM97 Escherichia coli APEC O1 hypothetical protein YP_001481252.1 85574 D 405955 CDS YP_001481253.1 157418181 5616606 85922..86767 1 NC_009837.1 IS629 transposase; similar to CAD88882; identified by match to protein family HMM PF00665; transposase 86767 5616606 APECO1_O1CoBM98 Escherichia coli APEC O1 transposase YP_001481253.1 85922 D 405955 CDS YP_001481254.1 157418182 5616607 complement(86860..88182) 1 NC_009837.1 putative iron transport system, membrane component; similar to ABA54770; identified by match to protein family HMM PF07690; EitD 88182 eitD 5616607 eitD Escherichia coli APEC O1 EitD YP_001481254.1 86860 R 405955 CDS YP_001481255.1 157418183 5616608 complement(88104..88868) 1 NC_009837.1 putative iron transport system, ATP-binding component; similar to AAX22060; identified by match to protein family HMM PF00005; EitC 88868 eitC 5616608 eitC Escherichia coli APEC O1 EitC YP_001481255.1 88104 R 405955 CDS YP_001481256.1 157418184 5616609 complement(88865..89902) 1 NC_009837.1 putative iron transport system, permease component; similar to AAX22061; identified by match to protein family HMM PF01032; EitB 89902 eitB 5616609 eitB Escherichia coli APEC O1 EitB YP_001481256.1 88865 R 405955 CDS YP_001481257.1 157418185 5616610 complement(89902..90900) 1 NC_009837.1 putative iron transport system, periplasmic binding protein; similar to AAX22062; identified by match to protein family HMM PF01497; EitA 90900 eitA 5616610 eitA Escherichia coli APEC O1 EitA YP_001481257.1 89902 R 405955 CDS YP_001481258.1 157418186 5616611 complement(91255..91845) 1 NC_009837.1 similar to EAN42275; identified by match to protein family HMM PF00239; resolvase 91845 5616611 APECO1_O1CoBM103 Escherichia coli APEC O1 resolvase YP_001481258.1 91255 R 405955 CDS YP_001481259.1 157418187 5616612 92346..92630 1 NC_009837.1 similar to AAC70078; identified by match to protein family HMM PF01402; ribbon-helix-helix protein, copG family domain; hypothetical protein 92630 5616612 APECO1_O1CoBM104 Escherichia coli APEC O1 hypothetical protein YP_001481259.1 92346 D 405955 CDS YP_001481260.1 157418188 5616613 92630..92905 1 NC_009837.1 similar to AAT94182; identified by match to protein family HMM PF05016; putative plasmid stabilization system protein; hypothetical protein 92905 5616613 APECO1_O1CoBM105 Escherichia coli APEC O1 hypothetical protein YP_001481260.1 92630 D 405955 CDS YP_001481261.1 157418189 5616614 complement(92987..93244) 1 NC_009837.1 similar to AAT94181; hypothetical protein 93244 5616614 APECO1_O1CoBM106 Escherichia coli APEC O1 hypothetical protein YP_001481261.1 92987 R 405955 CDS YP_001481262.1 157418190 5616615 complement(93413..94240) 1 NC_009837.1 IS1294 transposase; similar to AAM14707; transposase 94240 5616615 APECO1_O1CoBM107 Escherichia coli APEC O1 transposase YP_001481262.1 93413 R 405955 CDS YP_001481263.1 157418191 5616616 complement(94303..94704) 1 NC_009837.1 similar to ZP_00714559; hypothetical protein 94704 5616616 APECO1_O1CoBM108 Escherichia coli APEC O1 hypothetical protein YP_001481263.1 94303 R 405955 CDS YP_001481264.1 157418192 5616617 94722..94952 1 NC_009837.1 hypothetical protein 94952 5616617 APECO1_O1CoBM109 Escherichia coli APEC O1 hypothetical protein YP_001481264.1 94722 D 405955 CDS YP_001481265.1 157418193 5616618 94942..97080 1 NC_009837.1 similar to AAP42487; hypothetical protein 97080 5616618 APECO1_O1CoBM110 Escherichia coli APEC O1 hypothetical protein YP_001481265.1 94942 D 405955 CDS YP_001481266.1 157418194 5616619 complement(97242..97658) 1 NC_009837.1 virulence-associated gene D; similar to AAP42488; identified by match to protein family HMM PF01850; hypothetical protein 97658 vagD 5616619 vagD Escherichia coli APEC O1 hypothetical protein YP_001481266.1 97242 R 405955 CDS YP_001481267.1 157418195 5616620 complement(97655..97885) 1 NC_009837.1 virulence associated gene C; similar to AAP42489; identified by match to protein family HMM PF04014; hypothetical protein 97885 vagC 5616620 vagC Escherichia coli APEC O1 hypothetical protein YP_001481267.1 97655 R 405955 CDS YP_001481268.1 157418196 5616621 97973..98176 1 NC_009837.1 hypothetical protein 98176 5616621 APECO1_O1CoBM113 Escherichia coli APEC O1 hypothetical protein YP_001481268.1 97973 D 405955 CDS YP_001481269.1 157418197 5616622 98447..98797 1 NC_009837.1 similar to AAO49566; hypothetical protein 98797 5616622 APECO1_O1CoBM114 Escherichia coli APEC O1 hypothetical protein YP_001481269.1 98447 D 405955 CDS YP_001481270.1 157418198 5616623 98841..99530 1 NC_009837.1 similar to AAO49564; hypothetical protein 99530 5616623 APECO1_O1CoBM115 Escherichia coli APEC O1 hypothetical protein YP_001481270.1 98841 D 405955 CDS YP_001481271.1 157418199 5616624 99527..100318 1 NC_009837.1 putative site-specific recombinase; similar to YP_190186; identified by match to protein family HMM PF00589; resolvase 100318 5616624 APECO1_O1CoBM116 Escherichia coli APEC O1 resolvase YP_001481271.1 99527 D 405955 CDS YP_001481272.1 157418200 5616625 100424..100849 1 NC_009837.1 colicin M immunity protein; similar to IMMM_ECOLI; Cmi 100849 cmi 5616625 cmi Escherichia coli APEC O1 Cmi YP_001481272.1 100424 D 405955 CDS YP_001481273.1 157418201 5616626 complement(100899..101714) 1 NC_009837.1 colicin M activity protein; similar to CEAM_ECOLI; hypothetical protein 101714 cma 5616626 cma Escherichia coli APEC O1 hypothetical protein YP_001481273.1 100899 R 405955 CDS YP_001481274.1 157418203 5616627 101958..102485 1 NC_009837.1 colicin B immunity protein; similar to IMMB_ECOLI; Cbi 102485 cbi 5616627 cbi Escherichia coli APEC O1 Cbi YP_001481274.1 101958 D 405955 CDS YP_001481275.1 157418204 5616629 102518..102637 1 NC_009837.1 colicin B activity protein; similar to CEAB_ECOLI; Cba 102637 cba 5616629 cba Escherichia coli APEC O1 Cba YP_001481275.1 102518 D 405955 CDS YP_001481276.1 157418202 5616630 102843..103124 1 NC_009837.1 similar to AAT94181; hypothetical protein 103124 5616630 APECO1_O1CoBM121 Escherichia coli APEC O1 hypothetical protein YP_001481276.1 102843 D 405955 CDS YP_001481277.1 157418205 5616628 complement(103507..103695) 1 NC_009837.1 hypothetical protein 103695 5616628 APECO1_O1CoBM122 Escherichia coli APEC O1 hypothetical protein YP_001481277.1 103507 R 405955 CDS YP_001481278.1 157418206 5616631 complement(103670..105241) 1 NC_009837.1 fusion between colicin V secretion protein and transposase for IS186; assembly verified for accuracy; amino acids 1-195 are similar to 1-195 of IS186 transposase, amino acids 198-523 are similar to 45-362 of cvaB; similar to identified by match to protein family HMM PF01609; CvaB, IS186 transposase 105241 cvaB 5616631 cvaB Escherichia coli APEC O1 CvaB, IS186 transposase YP_001481278.1 103670 R 405955 CDS YP_001481279.1 157418207 5616632 complement(105216..106457) 1 NC_009837.1 colicin V secretion protein; similar to CAA40743; identified by match to protein family HMM PF00529; CvaA 106457 cvaA 5616632 cvaA Escherichia coli APEC O1 CvaA YP_001481279.1 105216 R 405955 CDS YP_001481280.1 157418208 5616633 complement(106687..107592) 1 NC_009837.1 transposase for IS2; similar to NP_418693; identified by match to protein family HMM PF00665; InsD 107592 insD 5616633 insD Escherichia coli APEC O1 InsD YP_001481280.1 106687 R 405955 CDS YP_001481281.1 157418209 5616634 complement(107550..107960) 1 NC_009837.1 IS2 transposase subunit; similar to NP_839581; identified by match to protein family HMM PF01527; IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 107960 insL 5616634 insL Escherichia coli APEC O1 insertion sequence 2 OrfA protein YP_001481281.1 107550 R 405955 CDS YP_001481282.1 157418210 5616635 complement(108234..108443) 1 NC_009837.1 similar to AAX22082; hypothetical protein 108443 5616635 APECO1_O1CoBM127 Escherichia coli APEC O1 hypothetical protein YP_001481282.1 108234 R 405955 CDS YP_001481283.1 157418211 5616636 108437..108706 1 NC_009837.1 unknown function; similar to AAZ05342; YacA 108706 yacA 5616636 yacA Escherichia coli APEC O1 YacA YP_001481283.1 108437 D 405955 CDS YP_001481284.1 157418212 5616637 108703..108984 1 NC_009837.1 plasmid stabilization system protein, RelE/ParE family superfamily; similar to YP_190105; identified by match to protein family HMM PF05016; YacB 108984 yacB 5616637 yacB Escherichia coli APEC O1 YacB YP_001481284.1 108703 D 405955 CDS YP_001481285.1 157418213 5616638 109030..109878 1 NC_009837.1 putative transposase; identified by match to protein family HMM PF00929; YacC 109878 yacC 5616638 yacC Escherichia coli APEC O1 YacC YP_001481285.1 109030 D 405955 CDS YP_001481286.1 157418214 5616639 109995..110477 1 NC_009837.1 putative cytoplasmic protein; similar to AAZ05345; YadA 110477 5616639 APECO1_O1CoBM130a Escherichia coli APEC O1 YadA YP_001481286.1 109995 D 405955 CDS YP_001481287.1 157418215 5616707 110779..111126 1 NC_009837.1 similar to YP_308785; hypothetical protein 111126 5616707 APECO1_O1CoBM131 Escherichia coli APEC O1 hypothetical protein YP_001481287.1 110779 D 405955 CDS YP_001481288.1 157418216 5616640 111130..111327 1 NC_009837.1 similar to AAX22086; hypothetical protein 111327 5616640 APECO1_O1CoBM132 Escherichia coli APEC O1 hypothetical protein YP_001481288.1 111130 D 405955 CDS YP_001481289.1 157418217 5616641 111476..111667 1 NC_009837.1 hypothetical protein 111667 5616641 APECO1_O1CoBM133 Escherichia coli APEC O1 hypothetical protein YP_001481289.1 111476 D 405955 CDS YP_001481290.1 157418218 5616642 111685..112626 1 NC_009837.1 similar to CAC43413; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 112626 5616642 APECO1_O1CoBM134 Escherichia coli APEC O1 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001481290.1 111685 D 405955 CDS YP_001481291.1 157418219 5616643 112641..112841 1 NC_009837.1 similar to NP_753138; hypothetical protein 112841 5616643 APECO1_O1CoBM135 Escherichia coli APEC O1 hypothetical protein YP_001481291.1 112641 D 405955 CDS YP_001481292.1 157418220 5616644 complement(113050..113277) 1 NC_009837.1 similar to AAX22088; hypothetical protein 113277 5616644 APECO1_O1CoBM136 Escherichia coli APEC O1 hypothetical protein YP_001481292.1 113050 R 405955 CDS YP_001481293.1 157418221 5616645 113575..115752 1 NC_009837.1 salmochelin siderophore system, salmochelin receptor; similar to AAS80269; identified by match to protein family HMM PF00593; Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 115752 iroN 5616645 iroN Escherichia coli APEC O1 outer membrane receptor FepA YP_001481293.1 113575 D 405955 CDS YP_001481294.1 157418222 5616646 complement(115797..116753) 1 NC_009837.1 salmochelin siderophore system component; similar to AAP42473; hypothetical protein 116753 5616646 APECO1_O1CoBM138 Escherichia coli APEC O1 hypothetical protein YP_001481294.1 115797 R 405955 CDS YP_001481295.1 157418223 5616647 complement(116838..118067) 1 NC_009837.1 salmochelin siderophore system, ferric enterochelin esterase; similar to AAS80267; identified by match to protein family HMM PF; IroD 118067 iroD 5616647 iroD Escherichia coli APEC O1 IroD YP_001481295.1 116838 R 405955 CDS YP_001481296.1 157418224 5616648 complement(118171..121956) 1 NC_009837.1 salmochelin siderophore system, ATP-binding cassette; similar to AAP41471; identified by match to protein family HMM PF00005; IroC 121956 iroC 5616648 iroC Escherichia coli APEC O1 IroC YP_001481296.1 118171 R 405955 CDS YP_001481297.1 157418225 5616649 complement(121970..123133) 1 NC_009837.1 salmochelin siderophore system, glycosyltransferase; similar to AAS80265; identified by match to protein family HMM PF06722; IroB 123133 iroB 5616649 iroB Escherichia coli APEC O1 IroB YP_001481297.1 121970 R 405955 CDS YP_001481298.1 157418226 5616650 complement(123284..123553) 1 NC_009837.1 similar to AAS80264; hypothetical protein 123553 5616650 APECO1_O1CoBM142 Escherichia coli APEC O1 hypothetical protein YP_001481298.1 123284 R 405955 CDS YP_001481299.1 157418227 5616651 complement(124321..124881) 1 NC_009837.1 putative integrase; similar to AAP42475; identified by match to protein family HMM PF00665; hypothetical protein 124881 5616651 APECO1_O1CoBM143 Escherichia coli APEC O1 hypothetical protein YP_001481299.1 124321 R 405955 CDS YP_001481300.1 157418228 5616652 complement(125072..125365) 1 NC_009837.1 similar to AAP42476; hypothetical protein 125365 5616652 APECO1_O1CoBM144 Escherichia coli APEC O1 hypothetical protein YP_001481300.1 125072 R 405955 CDS YP_001481301.1 157418229 5616653 complement(125931..126224) 1 NC_009837.1 similar to AAP41478; hypothetical protein 126224 5616653 APECO1_O1CoBM145 Escherichia coli APEC O1 hypothetical protein YP_001481301.1 125931 R 405955 CDS YP_001481302.1 157418230 5616654 complement(126237..126545) 1 NC_009837.1 increased serum survival protein; involved in complement resistance; similar to AAS80261; identified by match to protein family; Iss 126545 iss 5616654 iss Escherichia coli APEC O1 Iss YP_001481302.1 126237 R 405955 CDS YP_001481303.1 157418231 5616655 126696..126884 1 NC_009837.1 similar to AAX22091; hypothetical protein 126884 5616655 APECO1_O1CoBM147 Escherichia coli APEC O1 hypothetical protein YP_001481303.1 126696 D 405955 CDS YP_001481304.1 157418232 5616656 127112..127522 1 NC_009837.1 putative transposase; similar to NP_418692; identified by match to protein family HMM PF01527; IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 127522 insL 5616656 insL Escherichia coli APEC O1 insertion sequence 2 OrfA protein YP_001481304.1 127112 D 405955 CDS YP_001481305.1 157418233 5616657 127480..128385 1 NC_009837.1 IS2 transposase; similar to AAO49621; identified by match to protein family HMM PF00665; InsD 128385 insD 5616657 insD Escherichia coli APEC O1 InsD YP_001481305.1 127480 D 405955 CDS YP_001481306.1 157418234 5616658 128970..129194 1 NC_009837.1 hypothetical protein 129194 5616658 APECO1_O1CoBM150 Escherichia coli APEC O1 hypothetical protein YP_001481306.1 128970 D 405955 CDS YP_001481307.1 157418235 5616659 129609..130802 1 NC_009837.1 cobalamin synthesis protein cobW C-terminal domain; similar to AAX22904; identified by match to protein family HMM PF02492; hypothetical protein 130802 5616659 APECO1_O1CoBM151 Escherichia coli APEC O1 hypothetical protein YP_001481307.1 129609 D 405955 CDS YP_001481308.1 157418236 5616660 130935..131252 1 NC_009837.1 similar to AAX22096; hypothetical protein 131252 5616660 APECO1_O1CoBM152 Escherichia coli APEC O1 hypothetical protein YP_001481308.1 130935 D 405955 CDS YP_001481309.1 157418237 5616661 131439..132305 1 NC_009837.1 similar to AAX22097; hypothetical protein 132305 5616661 APECO1_O1CoBM153 Escherichia coli APEC O1 hypothetical protein YP_001481309.1 131439 D 405955 CDS YP_001481310.1 157418238 5616662 132442..132828 1 NC_009837.1 similar to AAX22097; hypothetical protein 132828 5616662 APECO1_O1CoBM154 Escherichia coli APEC O1 hypothetical protein YP_001481310.1 132442 D 405955 CDS YP_001481311.1 157418239 5616663 132865..133053 1 NC_009837.1 hypothetical protein 133053 5616663 APECO1_O1CoBM155 Escherichia coli APEC O1 hypothetical protein YP_001481311.1 132865 D 405955 CDS YP_001481312.1 157418240 5616664 133063..134004 1 NC_009837.1 similar to YP_268363; hypothetical protein 134004 5616664 APECO1_O1CoBM156 Escherichia coli APEC O1 hypothetical protein YP_001481312.1 133063 D 405955 CDS YP_001481313.1 157418241 5616665 complement(134100..134327) 1 NC_009837.1 hypothetical protein 134327 5616665 APECO1_O1CoBM157 Escherichia coli APEC O1 hypothetical protein YP_001481313.1 134100 R 405955 CDS YP_001481314.1 157418242 5616666 complement(134716..135219) 1 NC_009837.1 IS1 transposase; similar to AAO49620; identified by match to protein family HMM PF03400; hypothetical protein 135219 insB 5616666 insB Escherichia coli APEC O1 hypothetical protein YP_001481314.1 134716 R 405955 CDS YP_001481315.1 157418245 5616667 complement(135138..135413) 1 NC_009837.1 IS1 InsA protein; similar to AAO49621; hypothetical protein 135413 5616667 APECO1_O1CoBM159 Escherichia coli APEC O1 hypothetical protein YP_001481315.1 135138 R 405955 CDS YP_001481316.1 157418244 5616670 complement(135927..137429) 1 NC_009837.1 similar to AAO49625; hypothetical protein 137429 5616670 APECO1_O1CoBM160 Escherichia coli APEC O1 hypothetical protein YP_001481316.1 135927 R 405955 CDS YP_001481317.1 157418246 5616669 137715..137924 1 NC_009837.1 hypothetical protein 137924 5616669 APECO1_O1CoBM161 Escherichia coli APEC O1 hypothetical protein YP_001481317.1 137715 D 405955 CDS YP_001481318.1 157418247 5616671 complement(138064..138513) 1 NC_009837.1 hypothetical protein 138513 5616671 APECO1_O1CoBM162 Escherichia coli APEC O1 hypothetical protein YP_001481318.1 138064 R 405955 CDS YP_001481319.1 157418248 5616672 138631..139110 1 NC_009837.1 similar to AAO49623; hypothetical protein 139110 5616672 APECO1_O1CoBM163 Escherichia coli APEC O1 hypothetical protein YP_001481319.1 138631 D 405955 CDS YP_001481320.1 157418249 5616673 139550..140212 1 NC_009837.1 hypothetical protein 140212 5616673 APECO1_O1CoBM164 Escherichia coli APEC O1 hypothetical protein YP_001481320.1 139550 D 405955 CDS YP_001481321.1 157418250 5616674 complement(140223..140726) 1 NC_009837.1 IS1 transposase; similar to AAO49620; identified by match to protein family HMM PF03400; hypothetical protein 140726 insB 5616674 insB Escherichia coli APEC O1 hypothetical protein YP_001481321.1 140223 R 405955 CDS YP_001481322.1 157418243 5616675 complement(140645..140920) 1 NC_009837.1 IS1 InsA protein; similar to AAO49621; hypothetical protein 140920 5616675 APECO1_O1CoBM166 Escherichia coli APEC O1 hypothetical protein YP_001481322.1 140645 R 405955 CDS YP_001481323.1 157418251 5616668 141032..141304 1 NC_009837.1 similar to ABA54745; hypothetical protein 141304 5616668 APECO1_O1CoBM167 Escherichia coli APEC O1 hypothetical protein YP_001481323.1 141032 D 405955 CDS YP_001481324.1 157418252 5616676 complement(141445..143646) 1 NC_009837.1 aerobactin siderophore system, ferric aerobactin receptor protein; similar to ABA54744; identified by match to protein family HMM PF00593; IutA 143646 iutA 5616676 iutA Escherichia coli APEC O1 IutA YP_001481324.1 141445 R 405955 CDS YP_001481325.1 157418253 5616677 complement(143728..145005) 1 NC_009837.1 aerobactin siderophore system, L-lysine 6-monooxygenase; similar to CAE55774; IucD 145005 iucD 5616677 iucD Escherichia coli APEC O1 IucD YP_001481325.1 143728 R 405955 CDS YP_001481326.1 157418254 5616678 complement(145002..146744) 1 NC_009837.1 aerobactin siderophore system, aerobactin biosynthesis protein; similar to ABA54742; identified by match to protein family HMMPFO4183; IucC 146744 iucC 5616678 iucC Escherichia coli APEC O1 IucC YP_001481326.1 145002 R 405955 CDS YP_001481327.1 157418255 5616679 complement(146744..147691) 1 NC_009837.1 aerobactin siderophore system, N-hydroxylysine acetylase; similar to ABA54741; IucB 147691 5616679 APECO1_O1CoBM171 Escherichia coli APEC O1 IucB YP_001481327.1 146744 R 405955 CDS YP_001481328.1 157418256 5616680 complement(147692..149473) 1 NC_009837.1 aerobactin siderophore system, aerobactin synthetase; similar to ABA54740; identified by match to protein family HMM PF04183; IucA 149473 iucA 5616680 iucA Escherichia coli APEC O1 IucA YP_001481328.1 147692 R 405955 CDS YP_001481329.1 157418257 5616681 149552..150745 1 NC_009837.1 transporter, major facilitator family subfamily; similar to AAZ29623; identified by match to protein family HMM PF07690; ShiF 150745 shiF 5616681 shiF Escherichia coli APEC O1 ShiF YP_001481329.1 149552 D 405955 CDS YP_001481330.1 157418258 5616682 complement(151126..151506) 1 NC_009837.1 similar to CAH64818; identified by match to protein family HMM PF02537; may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 151506 crcB 5616682 crcB Escherichia coli APEC O1 camphor resistance protein CrcB YP_001481330.1 151126 R 405955 CDS YP_001481331.1 157418259 5616683 complement(151578..151850) 1 NC_009837.1 similar to ABA54737; hypothetical protein 151850 5616683 APECO1_O1CoBM175 Escherichia coli APEC O1 hypothetical protein YP_001481331.1 151578 R 405955 CDS YP_001481332.1 157418260 5616684 complement(151847..152176) 1 NC_009837.1 putative enolase, C-terminal TIM barrel domain; similar to CAH64819; identified by match to protein family HMM PF00113; hypothetical protein 152176 eno 5616684 eno Escherichia coli APEC O1 hypothetical protein YP_001481332.1 151847 R 405955 CDS YP_001481333.1 157418261 5616685 complement(152749..153606) 1 NC_009837.1 ABC iron transport system, inner membrane component; similar to ABA54734; identified by match to protein family HMM PF00950; SitD 153606 sitD 5616685 sitD Escherichia coli APEC O1 SitD YP_001481333.1 152749 R 405955 CDS YP_001481334.1 157418262 5616686 complement(153603..154460) 1 NC_009837.1 ABC iron transport system, permease component; similar to AAT11266; identified by match to protein family HMM PF00950; SitC 154460 sitC 5616686 sitC Escherichia coli APEC O1 SitC YP_001481334.1 153603 R 405955 CDS YP_001481335.1 157418263 5616687 complement(154457..155284) 1 NC_009837.1 ABC iron transport system, ATP-binding component; similar to ABA54732; identified by match to protein family HMM PF00005; SitB 155284 sitB 5616687 sitB Escherichia coli APEC O1 SitB YP_001481335.1 154457 R 405955 CDS YP_001481336.1 157418264 5616688 complement(155284..156198) 1 NC_009837.1 ABC iron transport system, periplasmic binding protein; similar to AAT11264; identified by match to protein family HMM PF01297; SitA 156198 sitA 5616688 sitA Escherichia coli APEC O1 SitA YP_001481336.1 155284 R 405955 CDS YP_001481337.1 157418265 5616689 156554..156829 1 NC_009837.1 IS1 InsA protein; similar to AAO49621; hypothetical protein 156829 insA 5616689 insA Escherichia coli APEC O1 hypothetical protein YP_001481337.1 156554 D 405955 CDS YP_001481338.1 157418266 5616690 156748..157251 1 NC_009837.1 IS1 transposase; similar to AAO49620; hypothetical protein 157251 insB 5616690 insB Escherichia coli APEC O1 hypothetical protein YP_001481338.1 156748 D 405955 CDS YP_001481339.1 157418267 5616691 complement(157431..157778) 1 NC_009837.1 similar to AAO49619; hypothetical protein 157778 5616691 APECO1_O1CoBM183 Escherichia coli APEC O1 hypothetical protein YP_001481339.1 157431 R 405955 CDS YP_001481340.1 157418268 5616692 complement(158078..158434) 1 NC_009837.1 IS21 transposase; similar to AAO49618; transposase 158434 5616692 APECO1_O1CoBM184 Escherichia coli APEC O1 transposase YP_001481340.1 158078 R 405955 CDS YP_001481341.1 157418269 5616693 158475..158771 1 NC_009837.1 similar to AAR05705; hypothetical protein 158771 5616693 APECO1_O1CoBM185 Escherichia coli APEC O1 hypothetical protein YP_001481341.1 158475 D 405955 CDS YP_001481342.1 157418270 5616694 159180..160157 1 NC_009837.1 repFIB replication protein; similar to AAO49616; identified by match to protein family HMM PF01051; hypothetical protein 160157 repA 5616694 repA Escherichia coli APEC O1 hypothetical protein YP_001481342.1 159180 D 405955 CDS YP_001481343.1 157418271 5616695 complement(160442..161182) 1 NC_009837.1 site-specific integrase; similar to AAO49615; identified by match to protein family HMM PF00589; hypothetical protein 161182 int 5616695 int Escherichia coli APEC O1 hypothetical protein YP_001481343.1 160442 R 405955 CDS YP_001481344.1 157418272 5616696 complement(161865..162773) 1 NC_009837.1 putative transcriptional regulator; similar to AAO49614; identified by match to protein family HMM PF07395; hypothetical protein 162773 5616696 APECO1_O1CoBM188 Escherichia coli APEC O1 hypothetical protein YP_001481344.1 161865 R 405955 CDS YP_001481345.1 157418273 5616697 complement(162836..163945) 1 NC_009837.1 putative avian hemolysin; similar to AAO49613; identified by match to protein family HMM PF01073; HlyF 163945 hlyF 5616697 hlyF Escherichia coli APEC O1 HlyF YP_001481345.1 162836 R 405955 CDS YP_001481346.1 157418274 5616698 164004..164288 1 NC_009837.1 hypothetical protein 164288 5616698 APECO1_O1CoBM190 Escherichia coli APEC O1 hypothetical protein YP_001481346.1 164004 D 405955 CDS YP_001481347.1 157418275 5616699 165436..165825 1 NC_009837.1 outer membrane protease; similar to ABA54754; identified by match to protein family HMM PF01278; OmpT 165825 ompT 5616699 ompT Escherichia coli APEC O1 OmpT YP_001481347.1 165436 D 405955 CDS YP_001481348.1 157418276 5616706 complement(166196..166456) 1 NC_009837.1 similar to ABA54756; hypothetical protein 166456 5616706 APECO1_O1CoBM193 Escherichia coli APEC O1 hypothetical protein YP_001481348.1 166196 R 405955 CDS YP_001481349.1 157418277 5616700 166967..167293 1 NC_009837.1 similar to NP_288505; hypothetical protein 167293 5616700 APECO1_O1CoBM194 Escherichia coli APEC O1 hypothetical protein YP_001481349.1 166967 D 405955 CDS YP_001481350.1 157418278 5616701 167290..168180 1 NC_009837.1 similar to CAD88882; identified by match to protein family HMM PF00665; IS629 transposase 168180 5616701 APECO1_O1CoBM195 Escherichia coli APEC O1 IS629 transposase YP_001481350.1 167290 D 405955 CDS YP_001481351.1 157418279 5616702 complement(168450..168740) 1 NC_009837.1 hypothetical protein 168740 5616702 APECO1_O1CoBM196 Escherichia coli APEC O1 hypothetical protein YP_001481351.1 168450 R 405955 CDS YP_001481352.1 157418280 5616703 169634..170821 1 NC_009837.1 E. coli transport system, membrane fusion protein; similar to ABA54761; identified by match to protein family HMM PF00529; EtsA 170821 etsA 5616703 etsA Escherichia coli APEC O1 EtsA YP_001481352.1 169634 D 405955 CDS YP_001481353.1 157418281 5616704 170818..172758 1 NC_009837.1 E. coli transport system, ATP-binding/permease protein; similar to ABA54762; identified by match to protein family HMM PF00005; EtsB 172758 etsB 5616704 etsB Escherichia coli APEC O1 EtsB YP_001481353.1 170818 D 405955 CDS YP_001481354.1 157418282 5616705 172762..174132 1 NC_009837.1 E. coli transport system, efflux protein; similar to ABA54763; identified by match to protein family HMM PF02321; EtsC 174132 etsC 5616705 etsC Escherichia coli APEC O1 EtsC YP_001481354.1 172762 D 405955 CDS YP_001481355.1 157412015 5616708 1..876 1 NC_009838.1 putative replication protein; hypothetical protein 876 repA 5616708 repA Escherichia coli APEC O1 hypothetical protein YP_001481355.1 1 D 405955 CDS YP_001481356.1 157412016 5616712 1998..2378 1 NC_009838.1 putative pilin presursor; HtdZ 2378 htdZ 5616712 htdZ Escherichia coli APEC O1 HtdZ YP_001481356.1 1998 D 405955 CDS YP_001481357.1 157412017 5616713 2396..2746 1 NC_009838.1 putative plasmid transfer protein; TrhL 2746 trhL 5616713 trhL Escherichia coli APEC O1 TrhL YP_001481357.1 2396 D 405955 CDS YP_001481358.1 157412018 5616714 2758..3546 1 NC_009838.1 putative pilus assembly protein; TrhE 3546 trhE 5616714 trhE Escherichia coli APEC O1 TrhE YP_001481358.1 2758 D 405955 CDS YP_001481359.1 157412019 5616715 3543..4817 1 NC_009838.1 TrhK 4817 trhK 5616715 trhK Escherichia coli APEC O1 TrhK YP_001481359.1 3543 D 405955 CDS YP_001481360.1 157412020 5616716 4819..5280 1 NC_009838.1 HtdO 5280 htdO 5616716 htdO Escherichia coli APEC O1 HtdO YP_001481360.1 4819 D 405955 CDS YP_001481361.1 157412021 5616717 5258..6625 1 NC_009838.1 putative transport protein; hypothetical protein 6625 trhB 5616717 trhB Escherichia coli APEC O1 hypothetical protein YP_001481361.1 5258 D 405955 CDS YP_001481362.1 157412022 5616718 6633..7115 1 NC_009838.1 HtdV 7115 htdV 5616718 htdV Escherichia coli APEC O1 HtdV YP_001481362.1 6633 D 405955 CDS YP_001481363.1 157412023 5616719 7006..7986 1 NC_009838.1 putative transfer-associated protein; HtdT 7986 htdT 5616719 htdT Escherichia coli APEC O1 HtdT YP_001481363.1 7006 D 405955 CDS YP_001481364.1 157412024 5616720 7996..8946 1 NC_009838.1 putative plasmid transfer protein; TrhV 8946 trhV 5616720 trhV Escherichia coli APEC O1 TrhV YP_001481364.1 7996 D 405955 CDS YP_001481365.1 157412025 5616721 8955..11636 1 NC_009838.1 putative pilus assembly protein; TrhC 11636 trhC 5616721 trhC Escherichia coli APEC O1 TrhC YP_001481365.1 8955 D 405955 CDS YP_001481366.1 157412026 5616722 16229..17482 1 NC_009838.1 putative plasmid partitioning protein; hypothetical protein 17482 parA 5616722 parA Escherichia coli APEC O1 hypothetical protein YP_001481366.1 16229 D 405955 CDS YP_001481367.1 157412027 5616723 17479..18483 1 NC_009838.1 putative plasmid partitioning protein; hypothetical protein 18483 parB 5616723 parB Escherichia coli APEC O1 hypothetical protein YP_001481367.1 17479 D 405955 CDS YP_001481368.1 157412028 5616724 complement(18545..18934) 1 NC_009838.1 TrhZ 18934 trhZ 5616724 trhZ Escherichia coli APEC O1 TrhZ YP_001481368.1 18545 R 405955 CDS YP_001481369.1 157412029 5616725 complement(18931..19452) 1 NC_009838.1 hypothetical protein 19452 5616725 APECO1_O1R15 Escherichia coli APEC O1 hypothetical protein YP_001481369.1 18931 R 405955 CDS YP_001481370.1 157412030 5616726 complement(19445..20281) 1 NC_009838.1 hypothetical protein 20281 5616726 APECO1_O1R16 Escherichia coli APEC O1 hypothetical protein YP_001481370.1 19445 R 405955 CDS YP_001481371.1 157412031 5616727 complement(20278..21225) 1 NC_009838.1 TrhO 21225 trhO 5616727 trhO Escherichia coli APEC O1 TrhO YP_001481371.1 20278 R 405955 CDS YP_001481372.1 157412032 5616728 21589..22626 1 NC_009838.1 plasmid partitioning protein; ParM 22626 parM 5616728 parM Escherichia coli APEC O1 ParM YP_001481372.1 21589 D 405955 CDS YP_001481373.1 157412033 5616729 22638..23276 1 NC_009838.1 plasmid partitioning protein; ParR 23276 parR 5616729 parR Escherichia coli APEC O1 ParR YP_001481373.1 22638 D 405955 CDS YP_001481374.1 157412034 5616730 complement(23624..24604) 1 NC_009838.1 putative transposase 24604 5616730 APECO1_O1R21 Escherichia coli APEC O1 putative transposase YP_001481374.1 23624 R 405955 CDS YP_001481375.1 157412035 5616731 24880..25332 1 NC_009838.1 IncHI2 transfer repressor; HtdA 25332 htdA 5616731 htdA Escherichia coli APEC O1 HtdA YP_001481375.1 24880 D 405955 CDS YP_001481376.1 157412036 5616732 25322..25747 1 NC_009838.1 putative exported plasmid transfer protein; HtdF 25747 htdF 5616732 htdF Escherichia coli APEC O1 HtdF YP_001481376.1 25322 D 405955 CDS YP_001481377.1 157412037 5616733 25729..26310 1 NC_009838.1 putative plasmid transfer protein 26310 hdtK 5616733 hdtK Escherichia coli APEC O1 putative plasmid transfer protein YP_001481377.1 25729 D 405955 CDS YP_001481378.1 157412038 5616734 26430..30734 1 NC_009838.1 hypothetical protein 30734 5616734 APECO1_O1R25 Escherichia coli APEC O1 hypothetical protein YP_001481378.1 26430 D 405955 CDS YP_001481379.1 157412039 5616735 31012..31524 1 NC_009838.1 putative signal peptidase; TrhF 31524 trhF 5616735 trhF Escherichia coli APEC O1 TrhF YP_001481379.1 31012 D 405955 CDS YP_001481380.1 157412040 5616736 31511..33022 1 NC_009838.1 putative transfer protein; TrhW 33022 trhW 5616736 trhW Escherichia coli APEC O1 TrhW YP_001481380.1 31511 D 405955 CDS YP_001481381.1 157412041 5616737 33062..34222 1 NC_009838.1 putative transfer protein; TrhU 34222 trhU 5616737 trhU Escherichia coli APEC O1 TrhU YP_001481381.1 33062 D 405955 CDS YP_001481382.1 157412042 5616738 34241..37429 1 NC_009838.1 putative transfer protein; TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 37429 trhN 5616738 trhN Escherichia coli APEC O1 conjugal transfer mating pair stabilization protein TraN YP_001481382.1 34241 D 405955 CDS YP_001481383.1 157412043 5616739 complement(37458..38330) 1 NC_009838.1 hypothetical protein 38330 5616739 APECO1_O1R30 Escherichia coli APEC O1 hypothetical protein YP_001481383.1 37458 R 405955 CDS YP_001481384.1 157412044 5616740 38510..40294 1 NC_009838.1 putative DNA helicase; TrhI 40294 trhI 5616740 trhI Escherichia coli APEC O1 TrhI YP_001481384.1 38510 D 405955 CDS YP_001481385.1 157412045 5616741 40689..41561 1 NC_009838.1 hypothetical protein 41561 5616741 APECO1_O1R32 Escherichia coli APEC O1 hypothetical protein YP_001481385.1 40689 D 405955 CDS YP_001481386.1 157412046 5616742 41619..41996 1 NC_009838.1 hypothetical protein 41996 5616742 APECO1_O1R33 Escherichia coli APEC O1 hypothetical protein YP_001481386.1 41619 D 405955 CDS YP_001481387.1 157412047 5616743 42057..43034 1 NC_009838.1 hypothetical protein 43034 5616743 APECO1_O1R34 Escherichia coli APEC O1 hypothetical protein YP_001481387.1 42057 D 405955 CDS YP_001481388.1 157412048 5616744 43092..44150 1 NC_009838.1 putative ATP-binding protein 44150 5616744 APECO1_O1R35 Escherichia coli APEC O1 putative ATP-binding protein YP_001481388.1 43092 D 405955 CDS YP_001481389.1 157412049 5616745 44519..45646 1 NC_009838.1 hypothetical protein 45646 5616745 APECO1_O1R36 Escherichia coli APEC O1 hypothetical protein YP_001481389.1 44519 D 405955 CDS YP_001481390.1 157412050 5616746 45724..47736 1 NC_009838.1 hypothetical protein 47736 5616746 APECO1_O1R37 Escherichia coli APEC O1 hypothetical protein YP_001481390.1 45724 D 405955 CDS YP_001481391.1 157412051 5616747 47808..48029 1 NC_009838.1 hypothetical protein 48029 5616747 APECO1_O1R38 Escherichia coli APEC O1 hypothetical protein YP_001481391.1 47808 D 405955 CDS YP_001481392.1 157412052 5616748 48071..49375 1 NC_009838.1 hypothetical protein 49375 5616748 APECO1_O1R39 Escherichia coli APEC O1 hypothetical protein YP_001481392.1 48071 D 405955 CDS YP_001481393.1 157412053 5616749 49646..50167 1 NC_009838.1 hypothetical protein 50167 5616749 APECO1_O1R40 Escherichia coli APEC O1 hypothetical protein YP_001481393.1 49646 D 405955 CDS YP_001481394.1 157412054 5616750 50246..51124 1 NC_009838.1 hypothetical protein 51124 5616750 APECO1_O1R41 Escherichia coli APEC O1 hypothetical protein YP_001481394.1 50246 D 405955 CDS YP_001481395.1 157412055 5616751 51195..52130 1 NC_009838.1 hypothetical protein 52130 5616751 APECO1_O1R42 Escherichia coli APEC O1 hypothetical protein YP_001481395.1 51195 D 405955 CDS YP_001481396.1 157412056 5616752 52199..53119 1 NC_009838.1 hypothetical protein 53119 5616752 APECO1_O1R43 Escherichia coli APEC O1 hypothetical protein YP_001481396.1 52199 D 405955 CDS YP_001481397.1 157412057 5616753 53186..54124 1 NC_009838.1 hypothetical protein 54124 5616753 APECO1_O1R44 Escherichia coli APEC O1 hypothetical protein YP_001481397.1 53186 D 405955 CDS YP_001481398.1 157412058 5616754 54290..55252 1 NC_009838.1 hypothetical protein 55252 5616754 APECO1_O1R45 Escherichia coli APEC O1 hypothetical protein YP_001481398.1 54290 D 405955 CDS YP_001481399.1 157412059 5616755 55516..55791 1 NC_009838.1 hypothetical protein 55791 5616755 APECO1_O1R46 Escherichia coli APEC O1 hypothetical protein YP_001481399.1 55516 D 405955 CDS YP_001481400.1 157412060 5616756 55836..56426 1 NC_009838.1 hypothetical protein 56426 5616756 APECO1_O1R47 Escherichia coli APEC O1 hypothetical protein YP_001481400.1 55836 D 405955 CDS YP_001481401.1 157412061 5616757 56434..56691 1 NC_009838.1 hypothetical protein 56691 5616757 APECO1_O1R48 Escherichia coli APEC O1 hypothetical protein YP_001481401.1 56434 D 405955 CDS YP_001481402.1 157412062 5616758 56765..57301 1 NC_009838.1 hypothetical protein 57301 5616758 APECO1_O1R49 Escherichia coli APEC O1 hypothetical protein YP_001481402.1 56765 D 405955 CDS YP_001481403.1 157412063 5616759 57318..57764 1 NC_009838.1 hypothetical protein 57764 5616759 APECO1_O1R50 Escherichia coli APEC O1 hypothetical protein YP_001481403.1 57318 D 405955 CDS YP_001481404.1 157412064 5616760 57837..58817 1 NC_009838.1 putative DNA replication termination protein 58817 5616760 APECO1_O1R51 Escherichia coli APEC O1 putative DNA replication termination protein YP_001481404.1 57837 D 405955 CDS YP_001481405.1 157412065 5616761 58827..59732 1 NC_009838.1 hypothetical protein 59732 5616761 APECO1_O1R52 Escherichia coli APEC O1 hypothetical protein YP_001481405.1 58827 D 405955 CDS YP_001481406.1 157412066 5616762 complement(60034..61218) 1 NC_009838.1 recombinase 61218 5616762 APECO1_O1R53 Escherichia coli APEC O1 recombinase YP_001481406.1 60034 R 405955 CDS YP_001481407.1 157412067 5616763 61953..63035 1 NC_009838.1 hypothetical protein 63035 5616763 APECO1_O1R54 Escherichia coli APEC O1 hypothetical protein YP_001481407.1 61953 D 405955 CDS YP_001481408.1 157412068 5616764 complement(63202..64755) 1 NC_009838.1 putative protein kinase 64755 5616764 APECO1_O1R55 Escherichia coli APEC O1 putative protein kinase YP_001481408.1 63202 R 405955 CDS YP_001481409.1 157412069 5616765 complement(64727..66364) 1 NC_009838.1 hypothetical protein 66364 5616765 APECO1_O1R56 Escherichia coli APEC O1 hypothetical protein YP_001481409.1 64727 R 405955 CDS YP_001481410.1 157412070 5616766 complement(66364..67404) 1 NC_009838.1 tellurite resistance protein; TerY3 67404 terY3 5616766 terY3 Escherichia coli APEC O1 TerY3 YP_001481410.1 66364 R 405955 CDS YP_001481411.1 157412071 5616767 complement(67490..68131) 1 NC_009838.1 tellurite resistance protein; TerY2 68131 terY2 5616767 terY2 Escherichia coli APEC O1 TerY2 YP_001481411.1 67490 R 405955 CDS YP_001481412.1 157412072 5616768 complement(68128..68769) 1 NC_009838.1 tellurite resistance protein; TerX 68769 terX 5616768 terX Escherichia coli APEC O1 TerX YP_001481412.1 68128 R 405955 CDS YP_001481413.1 157412073 5616769 complement(68792..69511) 1 NC_009838.1 tellurite resistance protein; TerY1 69511 terY1 5616769 terY1 Escherichia coli APEC O1 TerY1 YP_001481413.1 68792 R 405955 CDS YP_001481414.1 157412074 5616770 complement(69893..70360) 1 NC_009838.1 tellurite resistance protein; TerW 70360 terW 5616770 terW Escherichia coli APEC O1 TerW YP_001481414.1 69893 R 405955 CDS YP_001481415.1 157412075 5616771 complement(70378..71586) 1 NC_009838.1 hypothetical protein 71586 5616771 APECO1_O1R62 Escherichia coli APEC O1 hypothetical protein YP_001481415.1 70378 R 405955 CDS YP_001481416.1 157412076 5616772 complement(71597..72553) 1 NC_009838.1 hypothetical protein 72553 5616772 APECO1_O1R63 Escherichia coli APEC O1 hypothetical protein YP_001481416.1 71597 R 405955 CDS YP_001481417.1 157412077 5616773 complement(72553..73668) 1 NC_009838.1 putative ATP-binding protein 73668 5616773 APECO1_O1R64 Escherichia coli APEC O1 putative ATP-binding protein YP_001481417.1 72553 R 405955 CDS YP_001481418.1 157412078 5616774 complement(73634..74743) 1 NC_009838.1 hypothetical protein 74743 5616774 APECO1_O1R65 Escherichia coli APEC O1 hypothetical protein YP_001481418.1 73634 R 405955 CDS YP_001481419.1 157412079 5616775 complement(74400..75542) 1 NC_009838.1 hypothetical protein 75542 5616775 APECO1_O1R66 Escherichia coli APEC O1 hypothetical protein YP_001481419.1 74400 R 405955 CDS YP_001481420.1 157412080 5616776 complement(75552..76610) 1 NC_009838.1 hypothetical protein 76610 5616776 APECO1_O1R67 Escherichia coli APEC O1 hypothetical protein YP_001481420.1 75552 R 405955 CDS YP_001481421.1 157412081 5616777 76935..77516 1 NC_009838.1 tellurite resistance protein; TerZ 77516 terZ 5616777 terZ Escherichia coli APEC O1 TerZ YP_001481421.1 76935 D 405955 CDS YP_001481422.1 157412082 5616778 77516..78673 1 NC_009838.1 tellurite resistance protein; TerA 78673 terA 5616778 terA Escherichia coli APEC O1 TerA YP_001481422.1 77516 D 405955 CDS YP_001481423.1 157412083 5616779 78696..79151 1 NC_009838.1 tellurite resistance protein; TerB 79151 terB 5616779 terB Escherichia coli APEC O1 TerB YP_001481423.1 78696 D 405955 CDS YP_001481424.1 157412084 5616780 79174..80214 1 NC_009838.1 tellurite resistance protein; TerC 80214 terC 5616780 terC Escherichia coli APEC O1 TerC YP_001481424.1 79174 D 405955 CDS YP_001481425.1 157412085 5616781 80263..80841 1 NC_009838.1 tellurite resistance protein; TerD 80841 terD 5616781 terD Escherichia coli APEC O1 TerD YP_001481425.1 80263 D 405955 CDS YP_001481426.1 157412086 5616782 80705..81484 1 NC_009838.1 tellurite resistance protein; TerE 81484 terE 5616782 terE Escherichia coli APEC O1 TerE YP_001481426.1 80705 D 405955 CDS YP_001481427.1 157412087 5616783 81913..83154 1 NC_009838.1 tellurite resistance protein; TerF 83154 terF 5616783 terF Escherichia coli APEC O1 TerF YP_001481427.1 81913 D 405955 CDS YP_001481428.1 157412088 5616784 complement(84331..84702) 1 NC_009838.1 hypothetical protein 84702 5616784 APECO1_O1R75 Escherichia coli APEC O1 hypothetical protein YP_001481428.1 84331 R 405955 CDS YP_001481429.1 157412089 5616785 85006..85437 1 NC_009838.1 hypothetical protein 85437 5616785 APECO1_O1R76 Escherichia coli APEC O1 hypothetical protein YP_001481429.1 85006 D 405955 CDS YP_001481430.1 157412090 5616709 85416..85727 1 NC_009838.1 hypothetical protein 85727 5616709 APECO1_O1R77 Escherichia coli APEC O1 hypothetical protein YP_001481430.1 85416 D 405955 CDS YP_001481431.1 157412091 5616710 86038..86334 1 NC_009838.1 hypothetical protein 86334 5616710 APECO1_O1R78 Escherichia coli APEC O1 hypothetical protein YP_001481431.1 86038 D 405955 CDS YP_001481432.1 157412092 5616711 86339..87664 1 NC_009838.1 putative capsule biosynthesis protein 87664 5616711 APECO1_O1R79 Escherichia coli APEC O1 putative capsule biosynthesis protein YP_001481432.1 86339 D 405955 CDS YP_001481433.1 157412236 5616786 87801..88517 1 NC_009838.1 hypothetical protein 88517 tnpA 5616786 tnpA Escherichia coli APEC O1 hypothetical protein YP_001481433.1 87801 D 405955 CDS YP_001481434.1 157412093 5616787 88575..89078 1 NC_009838.1 hypothetical protein 89078 5616787 APECO1_O1R81 Escherichia coli APEC O1 hypothetical protein YP_001481434.1 88575 D 405955 CDS YP_001481435.1 157412094 5616788 complement(89361..89699) 1 NC_009838.1 hypothetical protein 89699 5616788 APECO1_O1R82 Escherichia coli APEC O1 hypothetical protein YP_001481435.1 89361 R 405955 CDS YP_001481436.1 157412095 5616789 complement(89603..90793) 1 NC_009838.1 tetracycline resistance protein; TetA 90793 tetA 5616789 tetA Escherichia coli APEC O1 TetA YP_001481436.1 89603 R 405955 CDS YP_001481437.1 157412096 5616790 90886..91545 1 NC_009838.1 tetracycline repressor protein; hypothetical protein 91545 tetR 5616790 tetR Escherichia coli APEC O1 hypothetical protein YP_001481437.1 90886 D 405955 CDS YP_001481438.1 157412097 5616791 complement(91623..94595) 1 NC_009838.1 transposase 94595 tnpA 5616791 tnpA Escherichia coli APEC O1 transposase YP_001481438.1 91623 R 405955 CDS YP_001481439.1 157412098 5616792 complement(94598..95077) 1 NC_009838.1 recombinase 95077 tnpR 5616792 tnpR Escherichia coli APEC O1 recombinase YP_001481439.1 94598 R 405955 CDS YP_001481440.1 157412099 5616793 complement(95193..95516) 1 NC_009838.1 transposition modulator protein 95516 tnpM 5616793 tnpM Escherichia coli APEC O1 transposition modulator protein YP_001481440.1 95193 R 405955 CDS YP_001481441.1 157412100 5616794 complement(95461..96474) 1 NC_009838.1 integrase for class 1 integron; IntI1 integrase 96474 intI1 5616794 intI1 Escherichia coli APEC O1 IntI1 integrase YP_001481441.1 95461 R 405955 CDS YP_001481442.2 229776987 5616795 96620..97411 1 NC_009838.1 streptomycin/spectinomycin resistance; adenlytransferase; streptomycin 3'-adenyltransferase; aminoglycoside resistance protein 97411 aadA 5616795 aadA Escherichia coli APEC O1 aminoglycoside resistance protein YP_001481442.2 96620 D 405955 CDS YP_001481443.1 157412102 5616796 97575..98477 1 NC_009838.1 gentamicin resistance protein; Aac3-VI 98477 aac3-VI 5616796 aac3-VI Escherichia coli APEC O1 Aac3-VI YP_001481443.1 97575 D 405955 CDS YP_001481444.1 157412103 5616797 99060..100697 1 NC_009838.1 chaperonin; heat shock protein; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 100697 groEL 5616797 groEL Escherichia coli APEC O1 chaperonin GroEL YP_001481444.1 99060 D 405955 CDS YP_001481445.1 157412104 5616798 100886..102415 1 NC_009838.1 transposase 102415 tnpA 5616798 tnpA Escherichia coli APEC O1 transposase YP_001481445.1 100886 D 405955 CDS YP_001481446.1 157412105 5616799 complement(101936..103855) 1 NC_009838.1 hypothetical protein 103855 5616799 APECO1_O1R93 Escherichia coli APEC O1 hypothetical protein YP_001481446.1 101936 R 405955 CDS YP_001481447.1 157412106 5616800 104136..104483 1 NC_009838.1 quaternary ammonium compound resistance protein 104483 qacEdelta1 5616800 qacEdelta1 Escherichia coli APEC O1 quaternary ammonium compound resistance protein YP_001481447.1 104136 D 405955 CDS YP_001481448.2 229776986 5616801 104477..105316 1 NC_009838.1 sulfonamide resistance; dihydropteroate synthase 105316 sulI 5616801 sulI Escherichia coli APEC O1 dihydropteroate synthase YP_001481448.2 104477 D 405955 CDS YP_001481449.1 157412108 5616802 105530..106255 1 NC_009838.1 hypothetical protein 106255 5616802 APECO1_O1R96 Escherichia coli APEC O1 hypothetical protein YP_001481449.1 105530 D 405955 CDS YP_001481450.1 157412109 5616803 complement(106376..107197) 1 NC_009838.1 putative transposase 107197 5616803 APECO1_O1R96.2 Escherichia coli APEC O1 putative transposase YP_001481450.1 106376 R 405955 CDS YP_001481451.1 157412110 5616804 107507..108580 1 NC_009838.1 putative transposase 108580 tnpA 5616804 tnpA Escherichia coli APEC O1 putative transposase YP_001481451.1 107507 D 405955 CDS YP_001481452.1 157412111 5616805 109164..110006 1 NC_009838.1 Tn7-like transposase; TnsA 110006 tnsA 5616805 tnsA Escherichia coli APEC O1 TnsA YP_001481452.1 109164 D 405955 CDS YP_001481453.1 157412112 5616806 109993..112116 1 NC_009838.1 Tn7-like transposase; TnsB 112116 tnsB 5616806 tnsB Escherichia coli APEC O1 TnsB YP_001481453.1 109993 D 405955 CDS YP_001481454.1 157412113 5616807 112116..113564 1 NC_009838.1 Tn7-like transposase; TnsC 113564 tnsC 5616807 tnsC Escherichia coli APEC O1 TnsC YP_001481454.1 112116 D 405955 CDS YP_001481455.1 157412114 5616808 113596..115161 1 NC_009838.1 Tn7-like transposase; TnsD 115161 tnsD 5616808 tnsD Escherichia coli APEC O1 TnsD YP_001481455.1 113596 D 405955 CDS YP_001481456.1 157412115 5616809 115173..115841 1 NC_009838.1 hypothetical protein 115841 5616809 APECO1_O1R102 Escherichia coli APEC O1 hypothetical protein YP_001481456.1 115173 D 405955 CDS YP_001481457.1 157412116 5616810 complement(115878..116801) 1 NC_009838.1 IS4 transposase 116801 tnpA 5616810 tnpA Escherichia coli APEC O1 IS4 transposase YP_001481457.1 115878 R 405955 CDS YP_001481458.1 157412117 5616811 116826..117164 1 NC_009838.1 hypothetical protein 117164 5616811 APECO1_O1R104 Escherichia coli APEC O1 hypothetical protein YP_001481458.1 116826 D 405955 CDS YP_001481459.1 157412118 5616812 117517..117816 1 NC_009838.1 putative transcriptional regulator 117816 5616812 APECO1_O1R105 Escherichia coli APEC O1 putative transcriptional regulator YP_001481459.1 117517 D 405955 CDS YP_001481460.1 157412119 5616813 118381..120207 1 NC_009838.1 ATP/GTP-binding protein 120207 5616813 APECO1_O1R106 Escherichia coli APEC O1 ATP/GTP-binding protein YP_001481460.1 118381 D 405955 CDS YP_001481461.1 157412120 5616814 120434..120775 1 NC_009838.1 hypothetical protein 120775 5616814 APECO1_O1R107 Escherichia coli APEC O1 hypothetical protein YP_001481461.1 120434 D 405955 CDS YP_001481462.1 157412121 5616815 complement(120874..121422) 1 NC_009838.1 silver binding protein; silver resistance; SilE 121422 silE 5616815 silE Escherichia coli APEC O1 SilE YP_001481462.1 120874 R 405955 CDS YP_001481463.1 157412122 5616816 complement(121550..123031) 1 NC_009838.1 putative sensor kinase; silver resistance; sensor kinase CusS 123031 silS 5616816 silS Escherichia coli APEC O1 sensor kinase CusS YP_001481463.1 121550 R 405955 CDS YP_001481464.1 157412123 5616817 complement(123024..123704) 1 NC_009838.1 putative transcriptional regulatory protein; silver resistance; response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 123704 silR 5616817 silR Escherichia coli APEC O1 DNA-binding transcriptional activator CusR YP_001481464.1 123024 R 405955 CDS YP_001481465.1 157412124 5616818 123591..125279 1 NC_009838.1 outer membrane efflux protein; silver resistance; with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 125279 silC 5616818 silC Escherichia coli APEC O1 copper/silver efflux system outer membrane protein CusC YP_001481465.1 123591 D 405955 CDS YP_001481466.1 157412125 5616819 125307..125660 1 NC_009838.1 periplasmic copper-binding protein 125660 5616819 APECO1_O1R112 Escherichia coli APEC O1 periplasmic copper-binding protein YP_001481466.1 125307 D 405955 CDS YP_001481467.1 157412126 5616820 125774..127066 1 NC_009838.1 silver resistance protein; with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 127066 silB 5616820 silB Escherichia coli APEC O1 copper/silver efflux system membrane fusion protein CusB YP_001481467.1 125774 D 405955 CDS YP_001481468.1 157412127 5616821 127077..130223 1 NC_009838.1 cation efflux system protein; silver resistance; SilA 130223 silA 5616821 silA Escherichia coli APEC O1 SilA YP_001481468.1 127077 D 405955 CDS YP_001481469.1 157412128 5616822 130304..130750 1 NC_009838.1 hypothetical protein 130750 5616822 APECO1_O1R115 Escherichia coli APEC O1 hypothetical protein YP_001481469.1 130304 D 405955 CDS YP_001481470.1 157412129 5616823 130877..133324 1 NC_009838.1 cation-transporting P-type ATPase; silver resistance; SilP 133324 silP 5616823 silP Escherichia coli APEC O1 SilP YP_001481470.1 130877 D 405955 CDS YP_001481471.1 157412130 5616824 complement(133596..134333) 1 NC_009838.1 putative peptidase 134333 5616824 APECO1_O1R117 Escherichia coli APEC O1 putative peptidase YP_001481471.1 133596 R 405955 CDS YP_001481472.1 157412131 5616825 complement(134622..135071) 1 NC_009838.1 copper resistance protein; PcoE 135071 pcoE 5616825 pcoE Escherichia coli APEC O1 PcoE YP_001481472.1 134622 R 405955 CDS YP_001481473.1 157412132 5616826 135300..137123 1 NC_009838.1 copper resistance protein; PcoA 137123 pcoA 5616826 pcoA Escherichia coli APEC O1 PcoA YP_001481473.1 135300 D 405955 CDS YP_001481474.1 157412133 5616827 137120..138019 1 NC_009838.1 copper resistance protein; PcoB 138019 pcoB 5616827 pcoB Escherichia coli APEC O1 PcoB YP_001481474.1 137120 D 405955 CDS YP_001481475.1 157412134 5616828 138059..138439 1 NC_009838.1 copper resistance protein; PcoC 138439 pcoC 5616828 pcoC Escherichia coli APEC O1 PcoC YP_001481475.1 138059 D 405955 CDS YP_001481476.1 157412135 5616829 138444..139373 1 NC_009838.1 copper resistance protein; PcoD 139373 pcoD 5616829 pcoD Escherichia coli APEC O1 PcoD YP_001481476.1 138444 D 405955 CDS YP_001481477.1 157412136 5616830 139428..140108 1 NC_009838.1 copper resistance regulatory protein; PcoR 140108 pcoR 5616830 pcoR Escherichia coli APEC O1 PcoR YP_001481477.1 139428 D 405955 CDS YP_001481478.1 157412137 5616831 140105..141505 1 NC_009838.1 copper resistance sensor kinase; PcoS 141505 pcoS 5616831 pcoS Escherichia coli APEC O1 PcoS YP_001481478.1 140105 D 405955 CDS YP_001481479.1 157412138 5616832 141723..142157 1 NC_009838.1 copper binding protein; PcoE 142157 pcoE 5616832 pcoE Escherichia coli APEC O1 PcoE YP_001481479.1 141723 D 405955 CDS YP_001481480.1 157412139 5616833 142523..143353 1 NC_009838.1 hypothetical protein 143353 5616833 APECO1_O1R124 Escherichia coli APEC O1 hypothetical protein YP_001481480.1 142523 D 405955 CDS YP_001481481.1 157412140 5616834 143350..144555 1 NC_009838.1 ATP/GTP-binding protein 144555 5616834 APECO1_O1R125 Escherichia coli APEC O1 ATP/GTP-binding protein YP_001481481.1 143350 D 405955 CDS YP_001481482.1 157412141 5616835 complement(144835..146154) 1 NC_009838.1 hypothetical protein 146154 5616835 APECO1_O1R126 Escherichia coli APEC O1 hypothetical protein YP_001481482.1 144835 R 405955 CDS YP_001481483.1 157412142 5616836 complement(146405..147874) 1 NC_009838.1 DNA cytosine methylase 147874 5616836 APECO1_O1R127 Escherichia coli APEC O1 DNA cytosine methylase YP_001481483.1 146405 R 405955 CDS YP_001481484.1 157412143 5616837 148008..148562 1 NC_009838.1 putative nuclease 148562 5616837 APECO1_O1R128 Escherichia coli APEC O1 putative nuclease YP_001481484.1 148008 D 405955 CDS YP_001481485.1 157412144 5616838 148481..149461 1 NC_009838.1 hypothetical protein 149461 5616838 APECO1_O1R129 Escherichia coli APEC O1 hypothetical protein YP_001481485.1 148481 D 405955 CDS YP_001481486.1 157412145 5616839 complement(149465..149716) 1 NC_009838.1 hypothetical protein 149716 5616839 APECO1_O1R130 Escherichia coli APEC O1 hypothetical protein YP_001481486.1 149465 R 405955 CDS YP_001481487.1 157412146 5616840 150782..151081 1 NC_009838.1 hypothetical protein 151081 5616840 APECO1_O1R131 Escherichia coli APEC O1 hypothetical protein YP_001481487.1 150782 D 405955 CDS YP_001481488.1 157412147 5616841 151418..151954 1 NC_009838.1 hypothetical protein 151954 5616841 APECO1_O1R132 Escherichia coli APEC O1 hypothetical protein YP_001481488.1 151418 D 405955 CDS YP_001481489.1 157412148 5616842 152016..152378 1 NC_009838.1 hypothetical protein 152378 5616842 APECO1_O1R133 Escherichia coli APEC O1 hypothetical protein YP_001481489.1 152016 D 405955 CDS YP_001481490.1 157412149 5616843 153315..154031 1 NC_009838.1 IS26 transposase 154031 tnpA 5616843 tnpA Escherichia coli APEC O1 IS26 transposase YP_001481490.1 153315 D 405955 CDS YP_001481491.1 157412150 5616844 154453..154887 1 NC_009838.1 UV protection and repair protein 154887 mucA 5616844 mucA Escherichia coli APEC O1 UV protection and repair protein YP_001481491.1 154453 D 405955 CDS YP_001481492.1 157412151 5616845 154871..156130 1 NC_009838.1 UV protection and repair protein 156130 mucB 5616845 mucB Escherichia coli APEC O1 UV protection and repair protein YP_001481492.1 154871 D 405955 CDS YP_001481493.1 157412152 5616846 complement(156176..156985) 1 NC_009838.1 hypothetical protein 156985 5616846 APECO1_O1R137 Escherichia coli APEC O1 hypothetical protein YP_001481493.1 156176 R 405955 CDS YP_001481494.1 157412153 5616847 157092..157703 1 NC_009838.1 hypothetical protein 157703 5616847 APECO1_O1R138 Escherichia coli APEC O1 hypothetical protein YP_001481494.1 157092 D 405955 CDS YP_001481495.1 157412154 5616848 complement(157763..158185) 1 NC_009838.1 hypothetical protein 158185 5616848 APECO1_O1R139 Escherichia coli APEC O1 hypothetical protein YP_001481495.1 157763 R 405955 CDS YP_001481496.1 157412155 5616849 complement(158219..158617) 1 NC_009838.1 hypothetical protein 158617 5616849 APECO1_O1R140 Escherichia coli APEC O1 hypothetical protein YP_001481496.1 158219 R 405955 CDS YP_001481497.1 157412156 5616850 complement(158636..159385) 1 NC_009838.1 thiol:disulfide interchange protein; DsbC 159385 dsbC 5616850 dsbC Escherichia coli APEC O1 DsbC YP_001481497.1 158636 R 405955 CDS YP_001481498.1 157412157 5616851 159533..160072 1 NC_009838.1 putative pilin biogenesis protein 160072 5616851 APECO1_O1R142 Escherichia coli APEC O1 putative pilin biogenesis protein YP_001481498.1 159533 D 405955 CDS YP_001481499.1 157412158 5616852 160203..160721 1 NC_009838.1 hypothetical protein 160721 5616852 APECO1_O1R143 Escherichia coli APEC O1 hypothetical protein YP_001481499.1 160203 D 405955 CDS YP_001481500.1 157412159 5616853 complement(160829..162118) 1 NC_009838.1 hypothetical protein 162118 5616853 APECO1_O1R144 Escherichia coli APEC O1 hypothetical protein YP_001481500.1 160829 R 405955 CDS YP_001481501.1 157412160 5616854 complement(162299..166252) 1 NC_009838.1 inner membrane protein 166252 trhG 5616854 trhG Escherichia coli APEC O1 inner membrane protein YP_001481501.1 162299 R 405955 CDS YP_001481502.1 157412161 5616855 complement(166261..167739) 1 NC_009838.1 pilus assembly protein 167739 trhH 5616855 trhH Escherichia coli APEC O1 pilus assembly protein YP_001481502.1 166261 R 405955 CDS YP_001481503.1 157412162 5616856 complement(167666..168712) 1 NC_009838.1 pilus assembly protein 168712 trhF 5616856 trhF Escherichia coli APEC O1 pilus assembly protein YP_001481503.1 167666 R 405955 CDS YP_001481504.1 157412163 5616857 complement(169306..169818) 1 NC_009838.1 plasmid transfer protein 169818 trhY 5616857 trhY Escherichia coli APEC O1 plasmid transfer protein YP_001481504.1 169306 R 405955 CDS YP_001481505.1 157412164 5616858 complement(169820..170620) 1 NC_009838.1 plasmid transfer protein 170620 trhR 5616858 trhR Escherichia coli APEC O1 plasmid transfer protein YP_001481505.1 169820 R 405955 CDS YP_001481506.1 157412165 5616859 171379..171864 1 NC_009838.1 plasmid transfer protein 171864 traH 5616859 traH Escherichia coli APEC O1 plasmid transfer protein YP_001481506.1 171379 D 405955 CDS YP_001481507.1 157412166 5616860 171861..172598 1 NC_009838.1 hypothetical protein 172598 5616860 APECO1_O1R151 Escherichia coli APEC O1 hypothetical protein YP_001481507.1 171861 D 405955 CDS YP_001481508.1 157412167 5616861 172602..175754 1 NC_009838.1 plasmid transfer protein; hypothetical protein 175754 traI 5616861 traI Escherichia coli APEC O1 hypothetical protein YP_001481508.1 172602 D 405955 CDS YP_001481509.1 157412168 5616862 175754..177838 1 NC_009838.1 plasmid transfer protein; hypothetical protein 177838 traG 5616862 traG Escherichia coli APEC O1 hypothetical protein YP_001481509.1 175754 D 405955 CDS YP_001481510.1 157412169 5616863 177838..178947 1 NC_009838.1 hypothetical protein 178947 5616863 APECO1_O1R154 Escherichia coli APEC O1 hypothetical protein YP_001481510.1 177838 D 405955 CDS YP_001481511.1 157412170 5616864 178916..179596 1 NC_009838.1 plasmid transfer protein; hypothetical protein 179596 traJ 5616864 traJ Escherichia coli APEC O1 hypothetical protein YP_001481511.1 178916 D 405955 CDS YP_001481512.1 157412171 5616865 179607..180788 1 NC_009838.1 hypothetical protein 180788 5616865 APECO1_O1R156 Escherichia coli APEC O1 hypothetical protein YP_001481512.1 179607 D 405955 CDS YP_001481513.1 157412172 5616866 180790..181521 1 NC_009838.1 hypothetical protein 181521 5616866 APECO1_O1R157 Escherichia coli APEC O1 hypothetical protein YP_001481513.1 180790 D 405955 CDS YP_001481514.1 157412173 5616867 complement(181808..182170) 1 NC_009838.1 hypothetical protein 182170 5616867 APECO1_O1R158 Escherichia coli APEC O1 hypothetical protein YP_001481514.1 181808 R 405955 CDS YP_001481515.1 157412174 5616868 complement(182227..182511) 1 NC_009838.1 hypothetical protein 182511 5616868 APECO1_O1R159 Escherichia coli APEC O1 hypothetical protein YP_001481515.1 182227 R 405955 CDS YP_001481516.1 157412175 5616869 complement(182868..183170) 1 NC_009838.1 hypothetical protein 183170 5616869 APECO1_O1R160 Escherichia coli APEC O1 hypothetical protein YP_001481516.1 182868 R 405955 CDS YP_001481517.1 157412176 5616870 complement(183603..183971) 1 NC_009838.1 hypothetical protein 183971 5616870 APECO1_O1R161 Escherichia coli APEC O1 hypothetical protein YP_001481517.1 183603 R 405955 CDS YP_001481518.1 157412177 5616871 complement(184136..184678) 1 NC_009838.1 hypothetical protein 184678 5616871 APECO1_O1R162 Escherichia coli APEC O1 hypothetical protein YP_001481518.1 184136 R 405955 CDS YP_001481519.1 157412178 5616872 complement(184740..185177) 1 NC_009838.1 hypothetical protein 185177 5616872 APECO1_O1R163 Escherichia coli APEC O1 hypothetical protein YP_001481519.1 184740 R 405955 CDS YP_001481520.1 157412179 5616873 complement(185222..185518) 1 NC_009838.1 hypothetical protein 185518 5616873 APECO1_O1R164 Escherichia coli APEC O1 hypothetical protein YP_001481520.1 185222 R 405955 CDS YP_001481521.1 157412180 5616874 186120..186512 1 NC_009838.1 hypothetical protein 186512 5616874 APECO1_O1R165 Escherichia coli APEC O1 hypothetical protein YP_001481521.1 186120 D 405955 CDS YP_001481522.1 157412181 5616875 complement(186449..187633) 1 NC_009838.1 putative DNA binding protein 187633 5616875 APECO1_O1R166 Escherichia coli APEC O1 putative DNA binding protein YP_001481522.1 186449 R 405955 CDS YP_001481523.1 157412182 5616876 187664..188044 1 NC_009838.1 hypothetical protein 188044 5616876 APECO1_O1R167 Escherichia coli APEC O1 hypothetical protein YP_001481523.1 187664 D 405955 CDS YP_001481524.1 157412183 5616877 complement(188049..188279) 1 NC_009838.1 hypothetical protein 188279 5616877 APECO1_O1R168 Escherichia coli APEC O1 hypothetical protein YP_001481524.1 188049 R 405955 CDS YP_001481525.1 157412184 5616878 188735..189679 1 NC_009838.1 hypothetical protein 189679 5616878 APECO1_O1R169 Escherichia coli APEC O1 hypothetical protein YP_001481525.1 188735 D 405955 CDS YP_001481526.1 157412185 5616879 189776..190378 1 NC_009838.1 hypothetical protein 190378 5616879 APECO1_O1R170 Escherichia coli APEC O1 hypothetical protein YP_001481526.1 189776 D 405955 CDS YP_001481527.1 157412186 5616880 190432..190788 1 NC_009838.1 hypothetical protein 190788 5616880 APECO1_O1R171 Escherichia coli APEC O1 hypothetical protein YP_001481527.1 190432 D 405955 CDS YP_001481528.1 157412187 5616881 complement(191047..191349) 1 NC_009838.1 hypothetical protein 191349 5616881 APECO1_O1R172 Escherichia coli APEC O1 hypothetical protein YP_001481528.1 191047 R 405955 CDS YP_001481529.1 157412188 5616882 complement(191456..191671) 1 NC_009838.1 plasmid stable inheritance protein; small toxic polypeptide 191671 stm 5616882 stm Escherichia coli APEC O1 small toxic polypeptide YP_001481529.1 191456 R 405955 CDS YP_001481530.1 157412189 5616883 complement(191969..192574) 1 NC_009838.1 hypothetical protein 192574 5616883 APECO1_O1R174 Escherichia coli APEC O1 hypothetical protein YP_001481530.1 191969 R 405955 CDS YP_001481531.1 157412190 5616884 192700..193113 1 NC_009838.1 hypothetical protein 193113 5616884 APECO1_O1R175 Escherichia coli APEC O1 hypothetical protein YP_001481531.1 192700 D 405955 CDS YP_001481532.1 157412191 5616885 complement(193446..193757) 1 NC_009838.1 hypothetical protein 193757 5616885 APECO1_O1R176 Escherichia coli APEC O1 hypothetical protein YP_001481532.1 193446 R 405955 CDS YP_001481533.1 157412192 5616886 194026..194427 1 NC_009838.1 hypothetical protein 194427 5616886 APECO1_O1R177 Escherichia coli APEC O1 hypothetical protein YP_001481533.1 194026 D 405955 CDS YP_001481534.1 157412193 5616887 complement(195255..195746) 1 NC_009838.1 hypothetical protein 195746 5616887 APECO1_O1R178 Escherichia coli APEC O1 hypothetical protein YP_001481534.1 195255 R 405955 CDS YP_001481535.1 157412194 5616888 complement(195751..196062) 1 NC_009838.1 hypothetical protein 196062 5616888 APECO1_O1R179 Escherichia coli APEC O1 hypothetical protein YP_001481535.1 195751 R 405955 CDS YP_001481536.1 157412195 5616889 complement(196578..196898) 1 NC_009838.1 hypothetical protein 196898 5616889 APECO1_O1R180 Escherichia coli APEC O1 hypothetical protein YP_001481536.1 196578 R 405955 CDS YP_001481537.1 157412196 5616890 complement(197078..197305) 1 NC_009838.1 hypothetical protein 197305 5616890 APECO1_O1R181 Escherichia coli APEC O1 hypothetical protein YP_001481537.1 197078 R 405955 CDS YP_001481538.1 157412197 5616891 complement(197533..198144) 1 NC_009838.1 hypothetical protein 198144 5616891 APECO1_O1R182 Escherichia coli APEC O1 hypothetical protein YP_001481538.1 197533 R 405955 CDS YP_001481539.1 157412198 5616892 complement(198256..198822) 1 NC_009838.1 hypothetical protein 198822 5616892 APECO1_O1R183 Escherichia coli APEC O1 hypothetical protein YP_001481539.1 198256 R 405955 CDS YP_001481540.1 157412199 5616893 complement(199035..199346) 1 NC_009838.1 hypothetical protein 199346 5616893 APECO1_O1R184 Escherichia coli APEC O1 hypothetical protein YP_001481540.1 199035 R 405955 CDS YP_001481541.1 157412200 5616894 199298..199651 1 NC_009838.1 hypothetical protein 199651 5616894 APECO1_O1R185 Escherichia coli APEC O1 hypothetical protein YP_001481541.1 199298 D 405955 CDS YP_001481542.1 157412201 5616895 complement(199898..202282) 1 NC_009838.1 hypothetical protein 202282 5616895 APECO1_O1R186 Escherichia coli APEC O1 hypothetical protein YP_001481542.1 199898 R 405955 CDS YP_001481543.1 157412202 5616896 complement(202454..202903) 1 NC_009838.1 hypothetical protein 202903 5616896 APECO1_O1R187 Escherichia coli APEC O1 hypothetical protein YP_001481543.1 202454 R 405955 CDS YP_001481544.1 157412203 5616897 complement(202955..203746) 1 NC_009838.1 hypothetical protein 203746 5616897 APECO1_O1R188 Escherichia coli APEC O1 hypothetical protein YP_001481544.1 202955 R 405955 CDS YP_001481545.1 157412204 5616898 complement(204122..205045) 1 NC_009838.1 putative transposase 205045 5616898 APECO1_O1R189 Escherichia coli APEC O1 putative transposase YP_001481545.1 204122 R 405955 CDS YP_001481546.1 157412205 5616899 205146..207218 1 NC_009838.1 hypothetical protein 207218 5616899 APECO1_O1R190 Escherichia coli APEC O1 hypothetical protein YP_001481546.1 205146 D 405955 CDS YP_001481547.1 157412237 5616900 208326..209414 1 NC_009838.1 RepH12 209414 repHI2 5616900 repHI2 Escherichia coli APEC O1 RepH12 YP_001481547.1 208326 D 405955 CDS YP_001481548.1 157412206 5616901 209778..210467 1 NC_009838.1 hypothetical protein 210467 5616901 APECO1_O1R192 Escherichia coli APEC O1 hypothetical protein YP_001481548.1 209778 D 405955 CDS YP_001481549.1 157412207 5616902 complement(211493..213913) 1 NC_009838.1 hypothetical protein 213913 5616902 APECO1_O1R193 Escherichia coli APEC O1 hypothetical protein YP_001481549.1 211493 R 405955 CDS YP_001481550.1 157412238 5616903 complement(214378..214989) 1 NC_009838.1 hypothetical protein 214989 5616903 APECO1_O1R194 Escherichia coli APEC O1 hypothetical protein YP_001481550.1 214378 R 405955 CDS YP_001481551.1 157412208 5616904 complement(215010..215273) 1 NC_009838.1 hypothetical protein 215273 5616904 APECO1_O1R195 Escherichia coli APEC O1 hypothetical protein YP_001481551.1 215010 R 405955 CDS YP_001481552.1 157412209 5616905 complement(215367..216128) 1 NC_009838.1 hypothetical protein 216128 5616905 APECO1_O1R196 Escherichia coli APEC O1 hypothetical protein YP_001481552.1 215367 R 405955 CDS YP_001481553.1 157412210 5616906 complement(216209..216973) 1 NC_009838.1 hypothetical protein 216973 5616906 APECO1_O1R197 Escherichia coli APEC O1 hypothetical protein YP_001481553.1 216209 R 405955 CDS YP_001481554.1 157412211 5616907 217303..217818 1 NC_009838.1 hypothetical protein 217818 5616907 APECO1_O1R198 Escherichia coli APEC O1 hypothetical protein YP_001481554.1 217303 D 405955 CDS YP_001481555.1 157412212 5616908 217922..218359 1 NC_009838.1 hypothetical protein 218359 5616908 APECO1_O1R199 Escherichia coli APEC O1 hypothetical protein YP_001481555.1 217922 D 405955 CDS YP_001481556.1 157412213 5616909 218346..218603 1 NC_009838.1 hypothetical protein 218603 5616909 APECO1_O1R200 Escherichia coli APEC O1 hypothetical protein YP_001481556.1 218346 D 405955 CDS YP_001481557.1 157412214 5616910 218811..219062 1 NC_009838.1 hypothetical protein 219062 5616910 APECO1_O1R201 Escherichia coli APEC O1 hypothetical protein YP_001481557.1 218811 D 405955 CDS YP_001481558.1 157412215 5616911 219439..221856 1 NC_009838.1 hypothetical protein 221856 5616911 APECO1_O1R202 Escherichia coli APEC O1 hypothetical protein YP_001481558.1 219439 D 405955 CDS YP_001481559.1 157412216 5616912 222291..222761 1 NC_009838.1 hypothetical protein 222761 5616912 APECO1_O1R203 Escherichia coli APEC O1 hypothetical protein YP_001481559.1 222291 D 405955 CDS YP_001481560.1 157412217 5616913 222811..223107 1 NC_009838.1 putative plasmid maintenance protein 223107 5616913 APECO1_O1R204 Escherichia coli APEC O1 putative plasmid maintenance protein YP_001481560.1 222811 D 405955 CDS YP_001481561.1 157412218 5616914 223116..224297 1 NC_009838.1 hypothetical protein 224297 5616914 APECO1_O1R205 Escherichia coli APEC O1 hypothetical protein YP_001481561.1 223116 D 405955 CDS YP_001481562.1 157412219 5616915 224705..225082 1 NC_009838.1 hypothetical protein 225082 5616915 APECO1_O1R206 Escherichia coli APEC O1 hypothetical protein YP_001481562.1 224705 D 405955 CDS YP_001481563.1 157412220 5616916 225177..225605 1 NC_009838.1 hypothetical protein 225605 5616916 APECO1_O1R207 Escherichia coli APEC O1 hypothetical protein YP_001481563.1 225177 D 405955 CDS YP_001481564.1 157412221 5616917 complement(225637..226023) 1 NC_009838.1 hypothetical protein 226023 5616917 APECO1_O1R208 Escherichia coli APEC O1 hypothetical protein YP_001481564.1 225637 R 405955 CDS YP_001481565.1 157412222 5616918 226083..226691 1 NC_009838.1 hypothetical protein 226691 5616918 APECO1_O1R209 Escherichia coli APEC O1 hypothetical protein YP_001481565.1 226083 D 405955 CDS YP_001481566.1 157412223 5616919 226860..228110 1 NC_009838.1 putative DNA methyltransferase 228110 5616919 APECO1_O1R210 Escherichia coli APEC O1 putative DNA methyltransferase YP_001481566.1 226860 D 405955 CDS YP_001481567.1 157412224 5616920 complement(228463..228768) 1 NC_009838.1 hypothetical protein 228768 5616920 APECO1_O1R211 Escherichia coli APEC O1 hypothetical protein YP_001481567.1 228463 R 405955 CDS YP_001481568.1 157412225 5616921 228953..229279 1 NC_009838.1 putative DNA methyltransferase 229279 5616921 APECO1_O1R212 Escherichia coli APEC O1 putative DNA methyltransferase YP_001481568.1 228953 D 405955 CDS YP_001481569.1 157412226 5616922 229594..230517 1 NC_009838.1 IS4 transposase 230517 5616922 APECO1_O1R213 Escherichia coli APEC O1 IS4 transposase YP_001481569.1 229594 D 405955 CDS YP_001481570.1 157412227 5616923 complement(230835..232370) 1 NC_009838.1 ISEc8 transposase 232370 5616923 APECO1_O1R214 Escherichia coli APEC O1 ISEc8 transposase YP_001481570.1 230835 R 405955 CDS YP_001481571.1 157412228 5616924 complement(232420..232767) 1 NC_009838.1 ISEc8 transposase 232767 5616924 APECO1_O1R215 Escherichia coli APEC O1 ISEc8 transposase YP_001481571.1 232420 R 405955 CDS YP_001481572.1 157412229 5616925 complement(232764..233147) 1 NC_009838.1 hypothetical protein 233147 5616925 APECO1_O1R216 Escherichia coli APEC O1 hypothetical protein YP_001481572.1 232764 R 405955 CDS YP_001481573.1 157412230 5616926 complement(233543..235234) 1 NC_009838.1 DNA restriction methylase 235234 5616926 APECO1_O1R217 Escherichia coli APEC O1 DNA restriction methylase YP_001481573.1 233543 R 405955 CDS YP_001481574.1 157412231 5616927 complement(235482..236645) 1 NC_009838.1 DNA-binding plasmid partitioning protein 236645 5616927 APECO1_O1R218 Escherichia coli APEC O1 DNA-binding plasmid partitioning protein YP_001481574.1 235482 R 405955 CDS YP_001481575.1 157412232 5616928 237015..237827 1 NC_009838.1 DNA adenine methylase 237827 dam 5616928 dam Escherichia coli APEC O1 DNA adenine methylase YP_001481575.1 237015 D 405955 CDS YP_001481576.1 157412233 5616929 complement(237836..238693) 1 NC_009838.1 hypothetical protein 238693 5616929 APECO1_O1R220 Escherichia coli APEC O1 hypothetical protein YP_001481576.1 237836 R 405955 CDS YP_001481577.1 157412234 5616930 complement(238925..239641) 1 NC_009838.1 hypothetical protein 239641 5616930 APECO1_O1R221 Escherichia coli APEC O1 hypothetical protein YP_001481577.1 238925 R 405955 CDS YP_001481578.1 157412235 5616931 complement(239856..240911) 1 NC_009838.1 hypothetical protein 240911 5616931 APECO1_O1R222 Escherichia coli APEC O1 hypothetical protein YP_001481578.1 239856 R 405955 CDS