-- dump date 20140619_081156 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 405955000001 SEQ_END SEQ_END NC_008563.1 5082025 5082025 DR NC_008563.1; contig end 5082025..5082025 Escherichia coli APEC O1 405955000002 SEQ_END SEQ_END NC_009837.1 174241 174241 DR NC_009837.1; contig end 174241..174241 Escherichia coli APEC O1 405955000003 SEQ_END SEQ_END NC_009838.1 241387 241387 DR NC_009838.1; contig end 241387..241387 Escherichia coli APEC O1 YP_851209.2 CDS thrA NC_008563.1 317 2779 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 317..2779 Escherichia coli APEC O1 4491344 YP_851210.1 CDS thrB NC_008563.1 2781 3713 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2781..3713 Escherichia coli APEC O1 4491345 YP_851211.1 CDS thrC NC_008563.1 3714 5000 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3714..5000 Escherichia coli APEC O1 4491346 YP_851212.1 CDS yaaX NC_008563.1 5214 5510 D hypothetical protein 5214..5510 Escherichia coli APEC O1 4491347 YP_851213.1 CDS yaaA NC_008563.1 5550 6326 R hypothetical protein complement(5550..6326) Escherichia coli APEC O1 4491348 YP_851214.1 CDS yaaJ NC_008563.1 6396 7826 R transporter YaaJ complement(6396..7826) Escherichia coli APEC O1 4491349 YP_851215.2 CDS talB NC_008563.1 8105 9058 D transaldolase B 8105..9058 Escherichia coli APEC O1 4491350 YP_851216.1 CDS mogA NC_008563.1 9173 9760 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9173..9760 Escherichia coli APEC O1 4491351 YP_851217.1 CDS yaaH NC_008563.1 9965 10531 R hypothetical protein complement(9965..10531) Escherichia coli APEC O1 4491352 YP_851218.1 CDS yaaW NC_008563.1 10680 11393 R hypothetical protein complement(10680..11393) Escherichia coli APEC O1 4491353 YP_851219.1 CDS yaaI NC_008563.1 11419 11823 R hypothetical protein complement(11419..11823) Escherichia coli APEC O1 4491354 YP_851220.1 CDS dnaK NC_008563.1 12195 14111 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12195..14111 Escherichia coli APEC O1 4491355 YP_851221.2 CDS dnaJ NC_008563.1 14200 15330 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 14200..15330 Escherichia coli APEC O1 4491356 YP_851222.1 CDS APECO1_1963 NC_008563.1 16199 16960 D hypothetical protein 16199..16960 Escherichia coli APEC O1 4491357 YP_851223.1 CDS aslA NC_008563.1 16950 18473 D arylsulfatase 16950..18473 Escherichia coli APEC O1 4491358 YP_851224.1 CDS APECO1_1961 NC_008563.1 18596 19861 D hypothetical protein 18596..19861 Escherichia coli APEC O1 4491359 YP_851225.1 CDS nhaA NC_008563.1 20096 21262 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 20096..21262 Escherichia coli APEC O1 4491360 YP_851226.1 CDS nhaR NC_008563.1 21322 22227 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 21322..22227 Escherichia coli APEC O1 4491361 YP_851227.1 CDS ribF NC_008563.1 22915 23856 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 22915..23856 Escherichia coli APEC O1 4491362 YP_851228.1 CDS ileS NC_008563.1 23899 26715 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 23899..26715 Escherichia coli APEC O1 4491420 YP_851229.1 CDS lspA NC_008563.1 26715 27209 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 26715..27209 Escherichia coli APEC O1 4491421 YP_851230.1 CDS slpA NC_008563.1 27317 27766 D FKBP-type peptidyl-prolyl cis-trans isomerase 27317..27766 Escherichia coli APEC O1 4491422 YP_851231.1 CDS ispH NC_008563.1 27768 28718 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 27768..28718 Escherichia coli APEC O1 4491423 YP_851232.1 CDS rihC NC_008563.1 28784 29698 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 28784..29698 Escherichia coli APEC O1 4491424 YP_851233.1 CDS APECO1_1952 NC_008563.1 29721 30086 D hypothetical protein 29721..30086 Escherichia coli APEC O1 4491425 YP_851234.1 CDS dapB NC_008563.1 30247 31068 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 30247..31068 Escherichia coli APEC O1 4491426 YP_851235.1 CDS carA NC_008563.1 31497 32672 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 31497..32672 Escherichia coli APEC O1 4491427 YP_851236.1 CDS carB NC_008563.1 32690 35911 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 32690..35911 Escherichia coli APEC O1 4491428 YP_851237.1 CDS APECO1_1948 NC_008563.1 36135 36593 D IS200-related; transposase 36135..36593 Escherichia coli APEC O1 4491429 YP_851238.1 CDS caiF NC_008563.1 36778 37278 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; CaiF family transcriptional regulator 36778..37278 Escherichia coli APEC O1 4491430 YP_851239.1 CDS caiE NC_008563.1 37397 38008 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(37397..38008) Escherichia coli APEC O1 4491431 YP_851240.2 CDS caiD NC_008563.1 37993 38778 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(37993..38778) Escherichia coli APEC O1 4491432 YP_851241.1 CDS caiC NC_008563.1 38887 40455 R crotonobetaine/carnitine-CoA ligase complement(38887..40455) Escherichia coli APEC O1 4491433 YP_851242.1 CDS caiB NC_008563.1 40513 41730 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(40513..41730) Escherichia coli APEC O1 4491434 YP_851243.1 CDS caiA NC_008563.1 41858 43000 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(41858..43000) Escherichia coli APEC O1 4491435 YP_851244.1 CDS caiT NC_008563.1 43031 44545 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(43031..44545) Escherichia coli APEC O1 4491436 YP_851245.1 CDS fixA NC_008563.1 44955 45788 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 44955..45788 Escherichia coli APEC O1 4491437 YP_851246.1 CDS fixB NC_008563.1 45803 46744 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 45803..46744 Escherichia coli APEC O1 4491438 YP_851247.1 CDS ydiS NC_008563.1 46795 48081 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 46795..48081 Escherichia coli APEC O1 4491439 YP_851248.1 CDS yaaU NC_008563.1 48424 49755 D metabolite transport protein YaaU 48424..49755 Escherichia coli APEC O1 4493283 YP_851249.1 CDS yabF NC_008563.1 49863 50393 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 49863..50393 Escherichia coli APEC O1 4493284 YP_851250.1 CDS kefC NC_008563.1 50314 52248 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 50314..52248 Escherichia coli APEC O1 4493285 YP_851251.1 CDS folA NC_008563.1 52305 52919 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52305..52919 Escherichia coli APEC O1 4493286 YP_851252.1 CDS apaH NC_008563.1 53553 54401 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(53553..54401) Escherichia coli APEC O1 4493287 YP_851253.1 CDS apaG NC_008563.1 54408 54785 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(54408..54785) Escherichia coli APEC O1 4493288 YP_851254.1 CDS ksgA NC_008563.1 54788 55609 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(54788..55609) Escherichia coli APEC O1 4493289 YP_851255.1 CDS pdxA NC_008563.1 55606 56595 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(55606..56595) Escherichia coli APEC O1 4493290 YP_851256.1 CDS surA NC_008563.1 56595 57881 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(56595..57881) Escherichia coli APEC O1 4493291 YP_851257.1 CDS imp NC_008563.1 57934 60288 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(57934..60288) Escherichia coli APEC O1 4493292 YP_851258.1 CDS djlA NC_008563.1 60450 61358 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 60450..61358 Escherichia coli APEC O1 4493293 YP_851259.1 CDS rluA NC_008563.1 61508 62167 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(61508..62167) Escherichia coli APEC O1 4493294 YP_851260.1 CDS hepA NC_008563.1 62179 65085 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(62179..65085) Escherichia coli APEC O1 4493295 YP_851261.1 CDS polB NC_008563.1 65249 67600 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(65249..67600) Escherichia coli APEC O1 4493296 YP_851262.1 CDS araD NC_008563.1 67675 68370 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(67675..68370) Escherichia coli APEC O1 4493297 YP_851263.1 CDS araA NC_008563.1 68655 70157 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(68655..70157) Escherichia coli APEC O1 4493298 YP_851264.1 CDS araB NC_008563.1 70168 71868 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(70168..71868) Escherichia coli APEC O1 4493299 YP_851265.1 CDS araC NC_008563.1 72156 73052 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; AraC family transcriptional regulator 72156..73052 Escherichia coli APEC O1 4493300 YP_851266.1 CDS APECO1_1919 NC_008563.1 73842 74414 D hypothetical protein 73842..74414 Escherichia coli APEC O1 4493301 YP_851267.1 CDS APECO1_1918 NC_008563.1 74421 74843 D hypothetical protein 74421..74843 Escherichia coli APEC O1 4493185 YP_851268.1 CDS yabI NC_008563.1 74998 75762 D integral membrane protein YabI 74998..75762 Escherichia coli APEC O1 4493186 YP_851269.1 CDS thiQ NC_008563.1 75876 76574 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(75876..76574) Escherichia coli APEC O1 4493187 YP_851270.1 CDS thiP NC_008563.1 76558 78168 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(76558..78168) Escherichia coli APEC O1 4493188 YP_851271.1 CDS tbpA NC_008563.1 78144 79139 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(78144..79139) Escherichia coli APEC O1 4493189 YP_851272.1 CDS sgrR NC_008563.1 79291 80946 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(79291..80946) Escherichia coli APEC O1 4493190 YP_851273.1 CDS leuD NC_008563.1 81274 81879 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(81274..81879) Escherichia coli APEC O1 4493191 YP_851274.1 CDS leuC NC_008563.1 81890 83290 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(81890..83290) Escherichia coli APEC O1 4493195 YP_851275.1 CDS leuB NC_008563.1 83293 84387 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(83293..84387) Escherichia coli APEC O1 4493196 YP_851276.1 CDS leuA NC_008563.1 84384 85955 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(84384..85955) Escherichia coli APEC O1 4493197 YP_851277.1 CDS leuO NC_008563.1 86707 87735 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 86707..87735 Escherichia coli APEC O1 4493198 YP_851278.1 CDS ilvI NC_008563.1 87963 89777 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 87963..89777 Escherichia coli APEC O1 4493199 YP_851279.1 CDS ilvH NC_008563.1 89750 90271 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 89750..90271 Escherichia coli APEC O1 4493200 YP_851280.1 CDS fruR NC_008563.1 90451 91455 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 90451..91455 Escherichia coli APEC O1 4493201 YP_851281.1 CDS mraW NC_008563.1 92418 93458 D S-adenosyl-methyltransferase MraW 92418..93458 Escherichia coli APEC O1 4493202 YP_851282.1 CDS ftsL NC_008563.1 93455 93820 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 93455..93820 Escherichia coli APEC O1 4493203 YP_851283.1 CDS ftsI NC_008563.1 93836 95602 D peptidoglycan synthetase FtsI 93836..95602 Escherichia coli APEC O1 4493204 YP_851284.1 CDS murE NC_008563.1 95589 97076 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 95589..97076 Escherichia coli APEC O1 4493067 YP_851285.1 CDS murF NC_008563.1 97073 98431 D UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 97073..98431 Escherichia coli APEC O1 4493068 YP_851286.1 CDS mraY NC_008563.1 98425 99507 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 98425..99507 Escherichia coli APEC O1 4493069 YP_851287.1 CDS murD NC_008563.1 99510 100826 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 99510..100826 Escherichia coli APEC O1 4493070 YP_851288.1 CDS ftsW NC_008563.1 100826 102070 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 100826..102070 Escherichia coli APEC O1 4493071 YP_851289.1 CDS murG NC_008563.1 102067 103134 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 102067..103134 Escherichia coli APEC O1 4493072 YP_851290.1 CDS murC NC_008563.1 103188 104663 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 103188..104663 Escherichia coli APEC O1 4493073 YP_851291.1 CDS ddl NC_008563.1 104656 105576 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 104656..105576 Escherichia coli APEC O1 4493074 YP_851292.1 CDS ftsQ NC_008563.1 105578 106408 D involved in septum formation; cell division protein FtsQ 105578..106408 Escherichia coli APEC O1 4493075 YP_851293.1 CDS ftsA NC_008563.1 106405 107667 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 106405..107667 Escherichia coli APEC O1 4493076 YP_851294.1 CDS ftsZ NC_008563.1 107728 108879 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 107728..108879 Escherichia coli APEC O1 4493077 YP_851295.1 CDS lpxC NC_008563.1 108980 109897 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 108980..109897 Escherichia coli APEC O1 4493078 YP_851296.1 CDS secM NC_008563.1 110053 110640 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 110053..110640 Escherichia coli APEC O1 4493079 YP_851297.1 CDS secA NC_008563.1 110702 113407 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 110702..113407 Escherichia coli APEC O1 4493080 YP_851298.1 CDS mutT NC_008563.1 113467 113865 D nucleoside triphosphate pyrophosphohydrolase 113467..113865 Escherichia coli APEC O1 4493081 YP_851299.1 CDS yacF NC_008563.1 114160 114903 R hypothetical protein complement(114160..114903) Escherichia coli APEC O1 4493082 YP_851300.1 CDS coaE NC_008563.1 114903 115523 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(114903..115523) Escherichia coli APEC O1 4493083 YP_851301.1 CDS guaC NC_008563.1 115748 116791 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 115748..116791 Escherichia coli APEC O1 4493084 YP_851302.1 CDS hofC NC_008563.1 116826 118028 R type IV pilin biogenesis protein complement(116826..118028) Escherichia coli APEC O1 4493085 YP_851303.1 CDS hofB NC_008563.1 118018 119403 R hypothetical protein complement(118018..119403) Escherichia coli APEC O1 4492796 YP_851304.1 CDS pppD NC_008563.1 119413 119853 R major pilin subunit complement(119413..119853) Escherichia coli APEC O1 4492797 YP_851305.1 CDS nadC NC_008563.1 120057 120992 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(120057..120992) Escherichia coli APEC O1 4492798 YP_851306.1 CDS ampD NC_008563.1 121038 121589 D regulator of AmpC; N-acetyl-anhydromuranmyl-L-alanine amidase 121038..121589 Escherichia coli APEC O1 4492799 YP_851307.1 CDS ampE NC_008563.1 121586 122440 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 121586..122440 Escherichia coli APEC O1 4492800 YP_851308.1 CDS aroP NC_008563.1 122483 123853 R aromatic amino acid transporter complement(122483..123853) Escherichia coli APEC O1 4492801 YP_851309.1 CDS usp NC_008563.1 124381 126162 D similar to bacteriocin protein; uropathogenic specific protein 124381..126162 Escherichia coli APEC O1 4492802 YP_851310.1 CDS APECO1_1875 NC_008563.1 126165 126449 D similar to colicin immunity protein; hypothetical protein 126165..126449 Escherichia coli APEC O1 4492803 YP_851311.1 CDS APECO1_1874 NC_008563.1 126857 127147 D similar to colicin immunity protein; hypothetical protein 126857..127147 Escherichia coli APEC O1 4492804 YP_851312.1 CDS APECO1_1873 NC_008563.1 127550 127846 D similar to colicin immunity protein; hypothetical protein 127550..127846 Escherichia coli APEC O1 4492805 YP_851313.1 CDS pdhR NC_008563.1 128302 129066 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 128302..129066 Escherichia coli APEC O1 4492806 YP_851314.1 CDS aceE NC_008563.1 129227 131890 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 129227..131890 Escherichia coli APEC O1 4492807 YP_851315.1 CDS aceF NC_008563.1 131905 133797 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 131905..133797 Escherichia coli APEC O1 4492808 YP_851316.1 CDS lpd NC_008563.1 134001 135428 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 134001..135428 Escherichia coli APEC O1 4492809 YP_851317.1 CDS yacH NC_008563.1 135670 137427 R hypothetical protein complement(135670..137427) Escherichia coli APEC O1 4492810 YP_851318.1 CDS acnB NC_008563.1 137629 140379 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 137629..140379 Escherichia coli APEC O1 4492811 YP_851319.1 CDS yacL NC_008563.1 140506 140766 D hypothetical protein 140506..140766 Escherichia coli APEC O1 4492812 YP_851320.1 CDS speD NC_008563.1 140950 141501 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(140950..141501) Escherichia coli APEC O1 4492813 YP_851321.1 CDS speE NC_008563.1 141760 142626 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(141760..142626) Escherichia coli APEC O1 4492814 YP_851322.1 CDS yacC NC_008563.1 142732 143118 R hypothetical protein complement(142732..143118) Escherichia coli APEC O1 4492815 YP_851323.1 CDS cueO NC_008563.1 143245 144795 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 143245..144795 Escherichia coli APEC O1 4491696 YP_851324.1 CDS gcd NC_008563.1 144842 147232 R glucose dehydrogenase complement(144842..147232) Escherichia coli APEC O1 4491697 YP_851325.1 CDS hpt NC_008563.1 147399 147974 D hypoxanthine-guanine phosphoribosyltransferase 147399..147974 Escherichia coli APEC O1 4491698 YP_851326.1 CDS yadF NC_008563.1 148015 148677 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(148015..148677) Escherichia coli APEC O1 4491699 YP_851327.1 CDS yadG NC_008563.1 148786 149712 D ABC transporter ATP-binding protein 148786..149712 Escherichia coli APEC O1 4491700 YP_851328.1 CDS APECO1_1857 NC_008563.1 149709 150479 D hypothetical protein 149709..150479 Escherichia coli APEC O1 4491701 YP_851329.1 CDS yadI NC_008563.1 150584 151024 D PTS system IIA component YadI 150584..151024 Escherichia coli APEC O1 4491702 YP_851330.1 CDS yadE NC_008563.1 151088 152317 D hypothetical protein 151088..152317 Escherichia coli APEC O1 4491703 YP_851331.1 CDS APECO1_1854 NC_008563.1 152321 152701 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(152321..152701) Escherichia coli APEC O1 4491704 YP_851332.1 CDS APECO1_1853 NC_008563.1 152975 153859 D hypothetical protein 152975..153859 Escherichia coli APEC O1 4491705 YP_851333.1 CDS panC NC_008563.1 153941 154792 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(153941..154792) Escherichia coli APEC O1 4491706 YP_851334.1 CDS panB NC_008563.1 154804 155598 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(154804..155598) Escherichia coli APEC O1 4491707 YP_851335.1 CDS yadC NC_008563.1 155710 156975 R fimbrial-like adhesin protein complement(155710..156975) Escherichia coli APEC O1 4491708 YP_851336.1 CDS yadK NC_008563.1 157025 157621 R hypothetical protein complement(157025..157621) Escherichia coli APEC O1 4491709 YP_851337.1 CDS yadL NC_008563.1 157648 158262 R hypothetical protein complement(157648..158262) Escherichia coli APEC O1 4491710 YP_851338.1 CDS yadM NC_008563.1 158268 158834 R fimbrial-like adhesin protein complement(158268..158834) Escherichia coli APEC O1 4491711 YP_851339.1 CDS htrE NC_008563.1 158851 161439 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(158851..161439) Escherichia coli APEC O1 4491712 YP_851340.1 CDS ecpD NC_008563.1 161474 162214 R chaperone protein EcpD complement(161474..162214) Escherichia coli APEC O1 4491713 YP_851341.1 CDS yadN NC_008563.1 162323 162937 R fimbrial-like adhesin protein complement(162323..162937) Escherichia coli APEC O1 4491714 YP_851342.1 CDS folK NC_008563.1 163275 163754 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(163275..163754) Escherichia coli APEC O1 4495464 YP_851343.1 CDS pcnB NC_008563.1 163751 165115 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I complement(163751..165115) Escherichia coli APEC O1 4495465 YP_851344.2 CDS yadB NC_008563.1 165208 166104 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(165208..166104) Escherichia coli APEC O1 4495466 YP_851345.1 CDS dksA NC_008563.1 166171 166644 R RNA polymerase-binding transcription factor complement(166171..166644) Escherichia coli APEC O1 4495467 YP_851346.1 CDS APECO1_1839 NC_008563.1 166804 167508 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(166804..167508) Escherichia coli APEC O1 4495468 YP_851347.1 CDS yadP NC_008563.1 167523 168266 R 2'-5' RNA ligase complement(167523..168266) Escherichia coli APEC O1 4495469 YP_851348.1 CDS hrpB NC_008563.1 168082 170556 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 168082..170556 Escherichia coli APEC O1 4495470 YP_851349.1 CDS mrcB NC_008563.1 170650 173184 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 170650..173184 Escherichia coli APEC O1 4495472 YP_851350.1 CDS fhuA NC_008563.1 173404 175647 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 173404..175647 Escherichia coli APEC O1 4495473 YP_851351.1 CDS fhuC NC_008563.1 175698 176495 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 175698..176495 Escherichia coli APEC O1 4495474 YP_851352.1 CDS fhuD NC_008563.1 176495 177385 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 176495..177385 Escherichia coli APEC O1 4495475 YP_851353.1 CDS fhuB NC_008563.1 177382 179364 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 177382..179364 Escherichia coli APEC O1 4495476 YP_851354.1 CDS hemL NC_008563.1 179399 180679 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(179399..180679) Escherichia coli APEC O1 4495477 YP_851355.1 CDS yadQ NC_008563.1 180904 182325 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 180904..182325 Escherichia coli APEC O1 4495478 YP_851356.1 CDS yadR NC_008563.1 182407 182751 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 182407..182751 Escherichia coli APEC O1 4495479 YP_851357.1 CDS yadS NC_008563.1 182798 183421 R hypothetical protein complement(182798..183421) Escherichia coli APEC O1 4495480 YP_851358.1 CDS yadT NC_008563.1 183459 184259 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(183459..184259) Escherichia coli APEC O1 4495481 YP_851359.1 CDS APECO1_1826 NC_008563.1 184252 184950 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(184252..184950) Escherichia coli APEC O1 4495482 YP_851360.1 CDS dgt NC_008563.1 185034 186551 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 185034..186551 Escherichia coli APEC O1 4495483 YP_851361.1 CDS htrA NC_008563.1 186681 188105 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 186681..188105 Escherichia coli APEC O1 4493684 YP_851362.1 CDS cdaR NC_008563.1 188283 189413 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 188283..189413 Escherichia coli APEC O1 4493685 YP_851363.1 CDS APECO1_1822 NC_008563.1 189467 189853 R hypothetical protein complement(189467..189853) Escherichia coli APEC O1 4493686 YP_851364.1 CDS dapD NC_008563.1 190165 190989 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(190165..190989) Escherichia coli APEC O1 4493687 YP_851365.1 CDS glnD NC_008563.1 191020 193692 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(191020..193692) Escherichia coli APEC O1 4493688 YP_851366.1 CDS map NC_008563.1 193754 194548 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(193754..194548) Escherichia coli APEC O1 4493689 YP_851367.1 CDS rpsB NC_008563.1 194916 195641 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 194916..195641 Escherichia coli APEC O1 4493690 YP_851368.1 CDS APECO1_1817 NC_008563.1 195593 196522 R hypothetical protein complement(195593..196522) Escherichia coli APEC O1 4493691 YP_851369.1 CDS pyrH NC_008563.1 196774 197499 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 196774..197499 Escherichia coli APEC O1 4493692 YP_851370.1 CDS frr NC_008563.1 197685 198206 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 197685..198206 Escherichia coli APEC O1 4493693 YP_851371.1 CDS dxr NC_008563.1 198298 199494 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 198298..199494 Escherichia coli APEC O1 4493694 YP_851372.1 CDS APECO1_1813 NC_008563.1 199680 200441 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 199680..200441 Escherichia coli APEC O1 4493695 YP_851373.1 CDS cdsA NC_008563.1 200484 201311 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 200484..201311 Escherichia coli APEC O1 4493696 YP_851374.1 CDS yaeL NC_008563.1 201323 202675 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 201323..202675 Escherichia coli APEC O1 4493697 YP_851375.1 CDS APECO1_1810 NC_008563.1 202705 205137 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 202705..205137 Escherichia coli APEC O1 4493698 YP_851376.1 CDS APECO1_1809 NC_008563.1 205259 205744 D periplasmic chaperone 205259..205744 Escherichia coli APEC O1 4493699 YP_851377.1 CDS lpxD NC_008563.1 205748 206773 D third step of endotoxin (lipidA) synthesis; adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 205748..206773 Escherichia coli APEC O1 4493700 YP_851378.1 CDS fabZ NC_008563.1 206953 207333 D (3R)-hydroxymyristoyl-ACP dehydratase 206953..207333 Escherichia coli APEC O1 4493701 YP_851379.1 CDS lpxA NC_008563.1 207337 208125 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 207337..208125 Escherichia coli APEC O1 4493702 YP_851380.1 CDS lpxB NC_008563.1 208125 209273 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 208125..209273 Escherichia coli APEC O1 4494815 YP_851381.1 CDS rnhB NC_008563.1 209270 209866 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 209270..209866 Escherichia coli APEC O1 4494816 YP_851382.1 CDS dnaE NC_008563.1 209903 213385 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 209903..213385 Escherichia coli APEC O1 4494817 YP_851383.1 CDS accA NC_008563.1 213398 214357 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 213398..214357 Escherichia coli APEC O1 4494818 YP_851384.1 CDS ldcC NC_008563.1 214455 216596 D lysine decarboxylase, constitutive 214455..216596 Escherichia coli APEC O1 4494819 YP_851385.1 CDS yaeR NC_008563.1 216626 217042 D hypothetical protein 216626..217042 Escherichia coli APEC O1 4494820 YP_851386.1 CDS tilS NC_008563.1 217107 218405 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 217107..218405 Escherichia coli APEC O1 4494821 YP_851387.1 CDS rof NC_008563.1 218453 218713 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(218453..218713) Escherichia coli APEC O1 4494822 YP_851388.1 CDS yaeQ NC_008563.1 219066 219611 D hypothetical protein 219066..219611 Escherichia coli APEC O1 4494823 YP_851389.1 CDS yaeJ NC_008563.1 219608 220030 D peptidyl-tRNA hydrolase domain-containing protein 219608..220030 Escherichia coli APEC O1 4494824 YP_851390.1 CDS cutF NC_008563.1 220044 220754 D lipoprotein involved with copper homeostasis and adhesion 220044..220754 Escherichia coli APEC O1 4494825 YP_851391.1 CDS yaeF NC_008563.1 220910 221734 R hypothetical protein complement(220910..221734) Escherichia coli APEC O1 4494826 YP_851392.1 CDS proS NC_008563.1 221787 223505 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(221787..223505) Escherichia coli APEC O1 4494827 YP_851393.1 CDS yaeB NC_008563.1 223616 224323 R hypothetical protein complement(223616..224323) Escherichia coli APEC O1 4494828 YP_851394.1 CDS rcsF NC_008563.1 224320 224724 R outer membrane lipoprotein complement(224320..224724) Escherichia coli APEC O1 4494829 YP_851395.1 CDS metQ NC_008563.1 224842 225657 R DL-methionine transporter substrate-binding subunit complement(224842..225657) Escherichia coli APEC O1 4494830 YP_851396.1 CDS metI NC_008563.1 225697 226350 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(225697..226350) Escherichia coli APEC O1 4494831 YP_851397.1 CDS metN NC_008563.1 226343 227374 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(226343..227374) Escherichia coli APEC O1 4494832 YP_851398.1 CDS yaeD NC_008563.1 227562 228134 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 227562..228134 Escherichia coli APEC O1 4494833 YP_851402.1 CDS dkgB NC_008563.1 233893 234696 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 233893..234696 Escherichia coli APEC O1 4495809 YP_851403.1 CDS APECO1_1782 NC_008563.1 234693 235607 R LysR family transcriptional regulator complement(234693..235607) Escherichia coli APEC O1 4495810 YP_851404.1 CDS yafD NC_008563.1 235824 236648 D hypothetical protein 235824..236648 Escherichia coli APEC O1 4495811 YP_851405.1 CDS yafE NC_008563.1 236726 237496 D hypothetical protein 236726..237496 Escherichia coli APEC O1 4495812 YP_851406.1 CDS mltD NC_008563.1 237543 238901 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(237543..238901) Escherichia coli APEC O1 4495813 YP_851407.1 CDS gloB NC_008563.1 238973 239728 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(238973..239728) Escherichia coli APEC O1 4495814 YP_851408.1 CDS yafS NC_008563.1 239744 240484 D S-adenosyl-L-methionine-dependent methyltransferase 239744..240484 Escherichia coli APEC O1 4495815 YP_851409.1 CDS rnhA NC_008563.1 240481 241059 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(240481..241059) Escherichia coli APEC O1 4495816 YP_851410.1 CDS dnaQ NC_008563.1 241004 241744 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 241004..241744 Escherichia coli APEC O1 4495817 YP_851412.1 CDS yafT NC_008563.1 242282 243067 D aminopeptidase 242282..243067 Escherichia coli APEC O1 4495819 YP_851413.1 CDS aec32 NC_008563.1 243407 243886 R similar to hemolysin co-regulated protein; hypothetical protein complement(243407..243886) Escherichia coli APEC O1 4495820 YP_851414.1 CDS aec31 NC_008563.1 243904 245403 R hypothetical protein complement(243904..245403) Escherichia coli APEC O1 4495821 YP_851415.1 CDS aec30 NC_008563.1 245273 248800 R similar to macrophage toxin; hypothetical protein complement(245273..248800) Escherichia coli APEC O1 4495822 YP_851416.1 CDS aec29 NC_008563.1 248820 250262 R hypothetical protein complement(248820..250262) Escherichia coli APEC O1 4495823 YP_851417.1 CDS aec28 NC_008563.1 250267 251010 R hypothetical protein complement(250267..251010) Escherichia coli APEC O1 4495824 YP_851418.1 CDS aec27 NC_008563.1 251007 253766 R ATPase complement(251007..253766) Escherichia coli APEC O1 4495825 YP_851419.1 CDS aec26 NC_008563.1 253776 254540 R hypothetical protein complement(253776..254540) Escherichia coli APEC O1 4495095 YP_851420.1 CDS aec25 NC_008563.1 254545 255891 R hypothetical protein complement(254545..255891) Escherichia coli APEC O1 4495096 YP_851421.1 CDS aec24 NC_008563.1 255894 256418 R hypothetical protein complement(255894..256418) Escherichia coli APEC O1 4495097 YP_851422.1 CDS aec23 NC_008563.1 256415 257707 R hypothetical protein complement(256415..257707) Escherichia coli APEC O1 4495098 YP_851423.1 CDS aec22 NC_008563.1 257712 258761 R hypothetical protein complement(257712..258761) Escherichia coli APEC O1 4495099 YP_851424.1 CDS APECO1_1761 NC_008563.1 258725 260575 R hypothetical protein complement(258725..260575) Escherichia coli APEC O1 4495100 YP_851425.1 CDS aec19 NC_008563.1 260572 260997 R hypothetical protein complement(260572..260997) Escherichia coli APEC O1 4495101 YP_851426.1 CDS aec18 NC_008563.1 261002 262486 R hypothetical protein complement(261002..262486) Escherichia coli APEC O1 4495102 YP_851427.1 CDS aec17 NC_008563.1 262509 263012 R hypothetical protein complement(262509..263012) Escherichia coli APEC O1 4495103 YP_851428.1 CDS aec16 NC_008563.1 263718 264236 D hypothetical protein 263718..264236 Escherichia coli APEC O1 4495104 YP_851429.1 CDS aec15 NC_008563.1 264457 266439 D hypothetical protein 264457..266439 Escherichia coli APEC O1 4495105 YP_851430.1 CDS aec14 NC_008563.1 266546 267592 D hypothetical protein 266546..267592 Escherichia coli APEC O1 4495106 YP_851431.1 CDS APECO1_1753 NC_008563.1 267585 269024 D hypothetical protein 267585..269024 Escherichia coli APEC O1 4495107 YP_851432.1 CDS aec11 NC_008563.1 268999 269289 D hypothetical protein 268999..269289 Escherichia coli APEC O1 4495108 YP_851433.1 CDS yhhI NC_008563.1 269826 270311 D transposase 269826..270311 Escherichia coli APEC O1 4495109 YP_851434.1 CDS aec8 NC_008563.1 270540 271043 D hypothetical protein 270540..271043 Escherichia coli APEC O1 4495110 YP_851435.1 CDS aec7 NC_008563.1 271113 271625 D hypothetical protein 271113..271625 Escherichia coli APEC O1 4495111 YP_851436.1 CDS yafV NC_008563.1 271896 272666 R hypothetical protein complement(271896..272666) Escherichia coli APEC O1 4495112 YP_851437.1 CDS ivy NC_008563.1 272820 273293 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 272820..273293 Escherichia coli APEC O1 4495113 YP_851438.2 CDS fadE NC_008563.1 273336 275780 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(273336..275780) Escherichia coli APEC O1 4495114 YP_851439.1 CDS gmhA NC_008563.1 275858 276598 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 275858..276598 Escherichia coli APEC O1 4495049 YP_851440.1 CDS yafJ NC_008563.1 276804 277571 D amidotransferase 276804..277571 Escherichia coli APEC O1 4495050 YP_851441.1 CDS yafK NC_008563.1 277542 278282 R hypothetical protein complement(277542..278282) Escherichia coli APEC O1 4495051 YP_851442.1 CDS yafL NC_008563.1 278585 279343 D lipoprotein 278585..279343 Escherichia coli APEC O1 4495052 YP_851443.1 CDS yafM NC_008563.1 279519 280016 D hypothetical protein 279519..280016 Escherichia coli APEC O1 4495053 YP_851444.1 CDS fhiA NC_008563.1 280336 282075 R FhiA protein complement(280336..282075) Escherichia coli APEC O1 4495054 YP_851445.1 CDS mbhA NC_008563.1 282020 282805 D hypothetical protein 282020..282805 Escherichia coli APEC O1 4495057 YP_851446.1 CDS dinB NC_008563.1 282876 283931 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 282876..283931 Escherichia coli APEC O1 4495059 YP_851447.1 CDS yafN NC_008563.1 283983 284276 D antitoxin of the YafO-YafN toxin-antitoxin system 283983..284276 Escherichia coli APEC O1 4495060 YP_851448.1 CDS APECO1_1736 NC_008563.1 284279 284677 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 284279..284677 Escherichia coli APEC O1 4495061 YP_851449.1 CDS yafP NC_008563.1 284687 285139 D hypothetical protein 284687..285139 Escherichia coli APEC O1 4495062 YP_851450.1 CDS APECO1_1734 NC_008563.1 285317 286468 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 285317..286468 Escherichia coli APEC O1 4495063 YP_851451.1 CDS prfH NC_008563.1 286381 287079 D similar to release factor 1 and 2; peptide chain release factor-like protein 286381..287079 Escherichia coli APEC O1 4495064 YP_851452.1 CDS pepD NC_008563.1 287136 288593 R aminoacyl-histidine dipeptidase complement(287136..288593) Escherichia coli APEC O1 4495065 YP_851453.1 CDS gpt NC_008563.1 288854 289312 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 288854..289312 Escherichia coli APEC O1 4495066 YP_851454.1 CDS frsA NC_008563.1 289404 290648 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 289404..290648 Escherichia coli APEC O1 4495067 YP_851455.1 CDS crl NC_008563.1 290706 291107 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 290706..291107 Escherichia coli APEC O1 4492718 YP_851456.1 CDS phoE NC_008563.1 291217 292278 R outer membrane phosphoporin protein E complement(291217..292278) Escherichia coli APEC O1 4492719 YP_851457.1 CDS proB NC_008563.1 292561 293664 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 292561..293664 Escherichia coli APEC O1 4492720 YP_851458.1 CDS proA NC_008563.1 293676 294929 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 293676..294929 Escherichia coli APEC O1 4492721 YP_851459.1 CDS APECO1_1725 NC_008563.1 295178 295492 R hypothetical protein complement(295178..295492) Escherichia coli APEC O1 4492722 YP_851460.1 CDS APECO1_1724 NC_008563.1 296225 296608 D hypothetical protein 296225..296608 Escherichia coli APEC O1 4492723 YP_851461.1 CDS APECO1_1723 NC_008563.1 299152 299841 D hypothetical protein 299152..299841 Escherichia coli APEC O1 4492724 YP_851462.1 CDS APECO1_1722 NC_008563.1 299853 300131 D hypothetical protein 299853..300131 Escherichia coli APEC O1 4492725 YP_851463.1 CDS APECO1_1721 NC_008563.1 300264 300668 D hypothetical protein 300264..300668 Escherichia coli APEC O1 4492726 YP_851464.1 CDS APECO1_1720 NC_008563.1 300646 301005 D hypothetical protein 300646..301005 Escherichia coli APEC O1 4492727 YP_851465.1 CDS APECO1_1719 NC_008563.1 301550 301912 D hypothetical protein 301550..301912 Escherichia coli APEC O1 4492728 YP_851466.1 CDS APECO1_1718 NC_008563.1 301931 302959 D hypothetical protein 301931..302959 Escherichia coli APEC O1 4492729 YP_851467.1 CDS APECO1_1717 NC_008563.1 303266 305095 D hypothetical protein 303266..305095 Escherichia coli APEC O1 4492730 YP_851468.1 CDS APECO1_1716 NC_008563.1 305130 305843 D hypothetical protein 305130..305843 Escherichia coli APEC O1 4492731 YP_851469.1 CDS APECO1_1715 NC_008563.1 305925 307259 R integrase complement(305925..307259) Escherichia coli APEC O1 4492732 YP_851470.1 CDS APECO1_1714 NC_008563.1 307569 307961 R integrase complement(307569..307961) Escherichia coli APEC O1 4492733 YP_851471.1 CDS APECO1_1713 NC_008563.1 308292 308816 R hypothetical protein complement(308292..308816) Escherichia coli APEC O1 4492734 YP_851472.1 CDS vat NC_008563.1 308942 313072 R hemoglobin protease; vacuolating autotransporter complement(308942..313072) Escherichia coli APEC O1 4492735 YP_851473.1 CDS APECO1_1711 NC_008563.1 314071 314346 R hypothetical protein complement(314071..314346) Escherichia coli APEC O1 4492737 YP_851474.1 CDS yagU NC_008563.1 315182 315796 D hypothetical protein 315182..315796 Escherichia coli APEC O1 4494875 YP_851475.1 CDS ykgJ NC_008563.1 316045 316374 R ferredoxin complement(316045..316374) Escherichia coli APEC O1 4494876 YP_851476.1 CDS yagV NC_008563.1 316681 317436 R hypothetical protein complement(316681..317436) Escherichia coli APEC O1 4494877 YP_851477.1 CDS yagW NC_008563.1 317360 319003 R hypothetical protein complement(317360..319003) Escherichia coli APEC O1 4494878 YP_851478.1 CDS yagX NC_008563.1 318993 321518 R hypothetical protein complement(318993..321518) Escherichia coli APEC O1 4494879 YP_851479.1 CDS yagY NC_008563.1 321544 322260 R hypothetical protein complement(321544..322260) Escherichia coli APEC O1 4494880 YP_851480.1 CDS matB NC_008563.1 322269 322856 R hypothetical protein complement(322269..322856) Escherichia coli APEC O1 4494881 YP_851481.1 CDS ykgK NC_008563.1 322930 323520 R hypothetical protein complement(322930..323520) Escherichia coli APEC O1 4494882 YP_851482.1 CDS APECO1_1702 NC_008563.1 323944 324234 D hypothetical protein 323944..324234 Escherichia coli APEC O1 4494883 YP_851483.1 CDS rpmE2 NC_008563.1 324696 324962 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(324696..324962) Escherichia coli APEC O1 4494884 YP_851484.1 CDS APECO1_1700 NC_008563.1 325899 327041 R NADH-dependent flavin oxidoreductase complement(325899..327041) Escherichia coli APEC O1 4494885 YP_851485.1 CDS ycjY NC_008563.1 327213 328133 R hypothetical protein complement(327213..328133) Escherichia coli APEC O1 4494886 YP_851486.1 CDS APECO1_1698 NC_008563.1 328227 329216 D LysR family transcriptional regulator 328227..329216 Escherichia coli APEC O1 4494887 YP_851487.1 CDS ycjZ NC_008563.1 329341 330309 D transcriptional regulator 329341..330309 Escherichia coli APEC O1 4494888 YP_851488.1 CDS APECO1_1696 NC_008563.1 330340 331329 R aldo/keto reductase complement(330340..331329) Escherichia coli APEC O1 4494889 YP_851489.1 CDS APECO1_1695 NC_008563.1 331356 332207 R 2,5-diketo-D-gluconic acid reductase A complement(331356..332207) Escherichia coli APEC O1 4494890 YP_851490.1 CDS eaeH NC_008563.1 332773 337023 D attaching and effacing protein, pathogenesis factor EaeH 332773..337023 Escherichia coli APEC O1 4494891 YP_851491.1 CDS ykgA NC_008563.1 337148 338038 R transcriptional regulator complement(337148..338038) Escherichia coli APEC O1 4494892 YP_851492.1 CDS APECO1_1692 NC_008563.1 338238 339122 D 2,5-diketo-D-gluconic acid reductase A 338238..339122 Escherichia coli APEC O1 4494893 YP_851493.1 CDS ykgB NC_008563.1 339282 339884 R hypothetical protein complement(339282..339884) Escherichia coli APEC O1 4495503 YP_851494.1 CDS ykgC NC_008563.1 340232 341584 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(340232..341584) Escherichia coli APEC O1 4495504 YP_851495.1 CDS ykgD NC_008563.1 341784 342638 D DNA-binding transcriptional regulator 341784..342638 Escherichia coli APEC O1 4495505 YP_851496.1 CDS ykgE NC_008563.1 343165 343884 D hypothetical protein 343165..343884 Escherichia coli APEC O1 4495506 YP_851497.1 CDS ykgG NC_008563.1 344022 345323 D hypothetical protein 344022..345323 Escherichia coli APEC O1 4495507 YP_851498.1 CDS ykgG NC_008563.1 345163 346011 D hypothetical protein 345163..346011 Escherichia coli APEC O1 4495508 YP_851499.1 CDS ykgH NC_008563.1 346254 346922 R hypothetical protein complement(346254..346922) Escherichia coli APEC O1 4495509 YP_851500.1 CDS APECO1_1684 NC_008563.1 347106 349418 R hypothetical protein complement(347106..349418) Escherichia coli APEC O1 4495510 YP_851501.1 CDS APECO1_1683 NC_008563.1 349445 350206 R hypothetical protein complement(349445..350206) Escherichia coli APEC O1 4495511 YP_851502.1 CDS APECO1_1682 NC_008563.1 350360 351154 R hypothetical protein complement(350360..351154) Escherichia coli APEC O1 4495512 YP_851503.1 CDS APECO1_1681 NC_008563.1 351484 352086 R hypothetical protein complement(351484..352086) Escherichia coli APEC O1 4495513 YP_851504.1 CDS APECO1_1680 NC_008563.1 352811 353092 D hypothetical protein 352811..353092 Escherichia coli APEC O1 4495514 YP_851505.2 CDS betA NC_008563.1 353117 354805 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(353117..354805) Escherichia coli APEC O1 4495515 YP_851506.1 CDS betB NC_008563.1 354819 356294 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(354819..356294) Escherichia coli APEC O1 4495516 YP_851507.1 CDS betI NC_008563.1 356305 356901 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(356305..356901) Escherichia coli APEC O1 4493869 YP_851508.1 CDS betT NC_008563.1 357021 359054 D proton-motive-force-driven choline transporter; choline transport protein BetT 357021..359054 Escherichia coli APEC O1 4493870 YP_851509.1 CDS yahA NC_008563.1 359926 361020 D DNA-binding transcriptional regulator 359926..361020 Escherichia coli APEC O1 4493871 YP_851510.1 CDS yahB NC_008563.1 361062 361994 R DNA-binding transcriptional regulator complement(361062..361994) Escherichia coli APEC O1 4493872 YP_851511.1 CDS yahC NC_008563.1 362086 362583 R hypothetical protein complement(362086..362583) Escherichia coli APEC O1 4493873 YP_851512.1 CDS yahD NC_008563.1 362841 363446 D transcription factor 362841..363446 Escherichia coli APEC O1 4493874 YP_851513.1 CDS yahE NC_008563.1 363486 364349 D hypothetical protein 363486..364349 Escherichia coli APEC O1 4493875 YP_851514.1 CDS yahF NC_008563.1 364339 365886 D acyl-CoA synthetase 364339..365886 Escherichia coli APEC O1 4493876 YP_851515.1 CDS APECO1_1669 NC_008563.1 365886 367304 D hypothetical protein 365886..367304 Escherichia coli APEC O1 4493877 YP_851516.1 CDS yahI NC_008563.1 367458 368408 D carbamate kinase 367458..368408 Escherichia coli APEC O1 4493878 YP_851517.1 CDS yahJ NC_008563.1 368418 369800 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 368418..369800 Escherichia coli APEC O1 4493879 YP_851518.1 CDS APECO1_1666 NC_008563.1 370098 370508 D hypothetical protein 370098..370508 Escherichia coli APEC O1 4493880 YP_851519.1 CDS APECO1_1665 NC_008563.1 370759 371745 D periplasmic binding protein, substrate ribose 370759..371745 Escherichia coli APEC O1 4493881 YP_851520.1 CDS APECO1_1664 NC_008563.1 371794 373278 D sugar ABC transporter ATP-binding protein 371794..373278 Escherichia coli APEC O1 4493882 YP_851521.1 CDS APECO1_1663 NC_008563.1 373271 374242 D ribose ABC transporter permease 373271..374242 Escherichia coli APEC O1 4493883 YP_851522.1 CDS APECO1_1662 NC_008563.1 374209 375195 D permease component of transport system 374209..375195 Escherichia coli APEC O1 4493884 YP_851523.1 CDS yahK NC_008563.1 375282 376331 D zinc-type alcohol dehydrogenase-like protein YahK 375282..376331 Escherichia coli APEC O1 4493885 YP_851524.1 CDS yahN NC_008563.1 377215 377886 R cytochrome subunit of dehydrogenase complement(377215..377886) Escherichia coli APEC O1 4493886 YP_851525.1 CDS yahO NC_008563.1 378033 378308 D hypothetical protein 378033..378308 Escherichia coli APEC O1 4493887 YP_851526.1 CDS prpR NC_008563.1 378409 379995 R DNA-binding transcriptional activator complement(378409..379995) Escherichia coli APEC O1 4494448 YP_851527.1 CDS prpB NC_008563.1 380234 381124 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 380234..381124 Escherichia coli APEC O1 4494449 YP_851528.1 CDS prpC NC_008563.1 381169 382338 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 381169..382338 Escherichia coli APEC O1 4494450 YP_851529.1 CDS prpD NC_008563.1 382372 383823 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 382372..383823 Escherichia coli APEC O1 4494451 YP_851530.1 CDS prpE NC_008563.1 383863 385749 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 383863..385749 Escherichia coli APEC O1 4494452 YP_851531.1 CDS codB NC_008563.1 386074 387333 D cytosine permease 386074..387333 Escherichia coli APEC O1 4494453 YP_851532.1 CDS codA NC_008563.1 387308 388606 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 387308..388606 Escherichia coli APEC O1 4494454 YP_851533.1 CDS lacA NC_008563.1 388727 389389 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(388727..389389) Escherichia coli APEC O1 4494455 YP_851534.1 CDS lacY NC_008563.1 389404 390657 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(389404..390657) Escherichia coli APEC O1 4494456 YP_851535.1 CDS lacZ NC_008563.1 390709 393783 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(390709..393783) Escherichia coli APEC O1 4494457 YP_851536.1 CDS lacI NC_008563.1 393907 394998 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(393907..394998) Escherichia coli APEC O1 4494458 YP_851537.1 CDS yaiL NC_008563.1 395191 395730 D nucleoprotein/polynucleotide-associated enzyme 395191..395730 Escherichia coli APEC O1 4494459 YP_851538.1 CDS yaiM NC_008563.1 395956 396789 R hypothetical protein complement(395956..396789) Escherichia coli APEC O1 4494460 YP_851539.1 CDS adhC NC_008563.1 396882 397991 R glutathione-dependent formaldehyde dehydrogenase complement(396882..397991) Escherichia coli APEC O1 4494461 YP_851540.1 CDS frmR NC_008563.1 398026 398322 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(398026..398322) Escherichia coli APEC O1 4494462 YP_851541.1 CDS yaiO NC_008563.1 398490 399263 R hypothetical protein complement(398490..399263) Escherichia coli APEC O1 4494463 YP_851542.1 CDS APECO1_1642 NC_008563.1 399265 399975 R transferase complement(399265..399975) Escherichia coli APEC O1 4494464 YP_851543.1 CDS yaiP NC_008563.1 399824 401020 R glucosyltransferase complement(399824..401020) Escherichia coli APEC O1 4494465 YP_851544.1 CDS APECO1_1640 NC_008563.1 401030 401716 R hypothetical protein complement(401030..401716) Escherichia coli APEC O1 4494466 YP_851545.1 CDS tauA NC_008563.1 402247 403266 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 402247..403266 Escherichia coli APEC O1 4494467 YP_851546.1 CDS tauB NC_008563.1 403279 404046 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 403279..404046 Escherichia coli APEC O1 4491940 YP_851547.1 CDS tauC NC_008563.1 404043 404870 D taurine transporter subunit 404043..404870 Escherichia coli APEC O1 4491941 YP_851548.1 CDS tauD NC_008563.1 404867 405718 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 404867..405718 Escherichia coli APEC O1 4491942 YP_851549.1 CDS hemB NC_008563.1 405758 406765 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(405758..406765) Escherichia coli APEC O1 4491943 YP_851550.1 CDS APECO1_1634 NC_008563.1 407258 410245 D structural protein 407258..410245 Escherichia coli APEC O1 4491944 YP_851551.1 CDS yaiV NC_008563.1 410286 410954 D DNA-binding transcriptional regulator 410286..410954 Escherichia coli APEC O1 4491945 YP_851552.1 CDS ampH NC_008563.1 410955 412085 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(410955..412085) Escherichia coli APEC O1 4491946 YP_851553.1 CDS sbmA NC_008563.1 412458 413684 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 412458..413684 Escherichia coli APEC O1 4491947 YP_851554.1 CDS yaiW NC_008563.1 413697 414791 D hypothetical protein 413697..414791 Escherichia coli APEC O1 4491948 YP_851555.1 CDS APECO1_1629 NC_008563.1 414850 415158 R hypothetical protein complement(414850..415158) Escherichia coli APEC O1 4491949 YP_851556.1 CDS yaiZ NC_008563.1 415286 415630 D hypothetical protein 415286..415630 Escherichia coli APEC O1 4491950 YP_851557.1 CDS ddl NC_008563.1 415654 416748 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(415654..416748) Escherichia coli APEC O1 4491951 YP_851558.1 CDS yaiB NC_008563.1 417211 417471 D hypothetical protein 417211..417471 Escherichia coli APEC O1 4491952 YP_851559.1 CDS phoA NC_008563.1 417572 418987 D alkaline phosphatase 417572..418987 Escherichia coli APEC O1 4491953 YP_851560.1 CDS psiF NC_008563.1 419088 419426 D hypothetical protein 419088..419426 Escherichia coli APEC O1 4491954 YP_851561.1 CDS adrA NC_008563.1 419528 420643 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 419528..420643 Escherichia coli APEC O1 4491955 YP_851562.1 CDS proC NC_008563.1 420660 421469 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(420660..421469) Escherichia coli APEC O1 4491956 YP_851563.1 CDS APECO1_1621 NC_008563.1 421589 422047 D hypothetical protein 421589..422047 Escherichia coli APEC O1 4491957 YP_851564.1 CDS aroL NC_008563.1 422230 422754 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 422230..422754 Escherichia coli APEC O1 4491958 YP_851565.1 CDS APECO1_1619 NC_008563.1 422744 423067 R hypothetical protein complement(422744..423067) Escherichia coli APEC O1 4492464 YP_851566.1 CDS aroM NC_008563.1 423253 423930 D hypothetical protein 423253..423930 Escherichia coli APEC O1 4492465 YP_851567.1 CDS APECO1_1617 NC_008563.1 424002 424286 D hypothetical protein 424002..424286 Escherichia coli APEC O1 4492466 YP_851568.1 CDS rdgC NC_008563.1 424933 425790 R Required for efficient pilin antigenic variation; recombination associated protein complement(424933..425790) Escherichia coli APEC O1 4492467 YP_851569.1 CDS yajF NC_008563.1 425844 426878 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 425844..426878 Escherichia coli APEC O1 4492468 YP_851570.1 CDS araJ NC_008563.1 427147 428367 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(427147..428367) Escherichia coli APEC O1 4492469 YP_851571.1 CDS sbcC NC_008563.1 428457 431600 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC complement(428457..431600) Escherichia coli APEC O1 4492470 YP_851572.1 CDS sbcD NC_008563.1 431597 432823 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD complement(431597..432823) Escherichia coli APEC O1 4492471 YP_851573.1 CDS phoB NC_008563.1 432989 433678 D sensor is PhoR; two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 432989..433678 Escherichia coli APEC O1 4492472 YP_851574.1 CDS phoR NC_008563.1 433736 435031 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 433736..435031 Escherichia coli APEC O1 4492473 YP_851575.1 CDS brnQ NC_008563.1 435438 436757 D branched-chain amino acid transport system II carrier protein 435438..436757 Escherichia coli APEC O1 4492474 YP_851576.1 CDS proY NC_008563.1 436833 438206 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 436833..438206 Escherichia coli APEC O1 4492475 YP_851577.1 CDS malZ NC_008563.1 438362 440179 D maltodextrin glucosidase 438362..440179 Escherichia coli APEC O1 4492476 YP_851578.1 CDS yajB NC_008563.1 440184 440822 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase complement(440184..440822) Escherichia coli APEC O1 4492477 YP_851579.1 CDS queA NC_008563.1 440984 442054 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 440984..442054 Escherichia coli APEC O1 4492478 YP_851580.1 CDS tgt NC_008563.1 442109 443236 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 442109..443236 Escherichia coli APEC O1 4492479 YP_851581.1 CDS yajC NC_008563.1 443259 443591 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 443259..443591 Escherichia coli APEC O1 4492480 YP_851582.1 CDS secD NC_008563.1 443619 445466 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 443619..445466 Escherichia coli APEC O1 4492481 YP_851583.1 CDS secF NC_008563.1 445432 446448 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 445432..446448 Escherichia coli APEC O1 4492482 YP_851584.1 CDS yajD NC_008563.1 446509 446925 D hypothetical protein 446509..446925 Escherichia coli APEC O1 4492483 YP_851585.1 CDS tsx NC_008563.1 446963 447847 R nucleoside-specific channel-forming protein Tsx complement(446963..447847) Escherichia coli APEC O1 4493703 YP_851586.1 CDS yajI NC_008563.1 448145 448744 R hypothetical protein complement(448145..448744) Escherichia coli APEC O1 4493704 YP_851587.1 CDS nrdR NC_008563.1 448835 449284 D NrdR family transcriptional regulator 448835..449284 Escherichia coli APEC O1 4493705 YP_851588.1 CDS ribD NC_008563.1 449288 450391 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 449288..450391 Escherichia coli APEC O1 4493706 YP_851589.1 CDS ribH NC_008563.1 450384 450950 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 450384..450950 Escherichia coli APEC O1 4493707 YP_851591.1 CDS thiL NC_008563.1 451467 452444 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 451467..452444 Escherichia coli APEC O1 4493709 YP_851592.1 CDS pgpA NC_008563.1 452422 452940 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 452422..452940 Escherichia coli APEC O1 4493710 YP_851593.1 CDS yajO NC_008563.1 452994 453968 R oxidoreductase, NAD(P)-binding complement(452994..453968) Escherichia coli APEC O1 4493711 YP_851594.1 CDS dxs NC_008563.1 454023 455885 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(454023..455885) Escherichia coli APEC O1 4493712 YP_851595.1 CDS ispA NC_008563.1 455910 456809 R geranyltranstransferase complement(455910..456809) Escherichia coli APEC O1 4493713 YP_851596.1 CDS thiI NC_008563.1 457257 458705 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 457257..458705 Escherichia coli APEC O1 4493714 YP_851597.1 CDS thiJ NC_008563.1 458759 459355 R DJ-1 family protein complement(458759..459355) Escherichia coli APEC O1 4493715 YP_851598.1 CDS apbA NC_008563.1 459312 460223 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(459312..460223) Escherichia coli APEC O1 4493716 YP_851599.1 CDS yajQ NC_008563.1 460373 460882 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 460373..460882 Escherichia coli APEC O1 4493717 YP_851600.1 CDS yajR NC_008563.1 461010 462380 R hypothetical protein complement(461010..462380) Escherichia coli APEC O1 4493718 YP_851601.1 CDS cyoE NC_008563.1 462523 463458 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(462523..463458) Escherichia coli APEC O1 4493719 YP_851602.1 CDS cyoD NC_008563.1 463425 463835 R cytochrome o ubiquinol oxidase subunit IV complement(463425..463835) Escherichia coli APEC O1 4493720 YP_851603.1 CDS cyoC NC_008563.1 463754 464368 R cytochrome o ubiquinol oxidase subunit III complement(463754..464368) Escherichia coli APEC O1 4493721 YP_851604.1 CDS cyoB NC_008563.1 464358 466349 R cytochrome o ubiquinol oxidase subunit I complement(464358..466349) Escherichia coli APEC O1 4492874 YP_851605.1 CDS cyoA NC_008563.1 466371 467327 R cytochrome o ubiquinol oxidase subunit II complement(466371..467327) Escherichia coli APEC O1 4492875 YP_851606.1 CDS ampG NC_008563.1 467786 469261 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(467786..469261) Escherichia coli APEC O1 4492876 YP_851607.1 CDS yajG NC_008563.1 469305 469985 R hypothetical protein complement(469305..469985) Escherichia coli APEC O1 4492877 YP_851608.2 CDS bolA NC_008563.1 470188 470505 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 470188..470505 Escherichia coli APEC O1 4492878 YP_851609.1 CDS tig NC_008563.1 470849 472138 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 470849..472138 Escherichia coli APEC O1 4492879 YP_851610.1 CDS clpP NC_008563.1 472393 473016 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 472393..473016 Escherichia coli APEC O1 4492880 YP_851611.1 CDS clpX NC_008563.1 473142 474416 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 473142..474416 Escherichia coli APEC O1 4492881 YP_851612.1 CDS lon NC_008563.1 474559 476958 D DNA-binding ATP-dependent protease La 474559..476958 Escherichia coli APEC O1 4492882 YP_851613.1 CDS hupB NC_008563.1 477167 477439 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 477167..477439 Escherichia coli APEC O1 4492883 YP_851614.1 CDS ppiD NC_008563.1 477631 479502 D peptidyl-prolyl cis-trans isomerase 477631..479502 Escherichia coli APEC O1 4492884 YP_851615.1 CDS ybaV NC_008563.1 479653 480024 D hypothetical protein 479653..480024 Escherichia coli APEC O1 4492885 YP_851616.1 CDS ybaW NC_008563.1 480130 480528 D hypothetical protein 480130..480528 Escherichia coli APEC O1 4492886 YP_851617.1 CDS APECO1_1567 NC_008563.1 480580 481275 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(480580..481275) Escherichia coli APEC O1 4492887 YP_851618.1 CDS ybaE NC_008563.1 481340 483040 R hypothetical protein complement(481340..483040) Escherichia coli APEC O1 4492888 YP_851619.1 CDS cof NC_008563.1 483128 483958 D hypothetical protein 483128..483958 Escherichia coli APEC O1 4492889 YP_851620.1 CDS ybaO NC_008563.1 483958 484569 D transcriptional regulator YbaO 483958..484569 Escherichia coli APEC O1 4492890 YP_851621.1 CDS mdlA NC_008563.1 484599 486371 D multidrug transporter membrane\ATP-binding components 484599..486371 Escherichia coli APEC O1 4492891 YP_851622.2 CDS mdlB NC_008563.1 486364 488145 D multidrug transporter membrane\ATP-binding components 486364..488145 Escherichia coli APEC O1 4492892 YP_851623.1 CDS glnK NC_008563.1 488188 488664 D glutamine synthetase 488188..488664 Escherichia coli APEC O1 4492893 YP_851624.1 CDS amtB NC_008563.1 488694 489980 D ammonium transporter 488694..489980 Escherichia coli APEC O1 4494024 YP_851625.1 CDS tesB NC_008563.1 490029 490889 R acyl-CoA thioesterase II complement(490029..490889) Escherichia coli APEC O1 4494025 YP_851626.1 CDS ybaY NC_008563.1 491107 491679 D lipoprotein 491107..491679 Escherichia coli APEC O1 4494026 YP_851627.1 CDS ybaZ NC_008563.1 491710 492099 R hypothetical protein complement(491710..492099) Escherichia coli APEC O1 4494027 YP_851628.1 CDS APECO1_1556 NC_008563.1 492400 492753 D hypothetical protein 492400..492753 Escherichia coli APEC O1 4494028 YP_851629.1 CDS ylaB NC_008563.1 492795 494351 R hypothetical protein complement(492795..494351) Escherichia coli APEC O1 4494029 YP_851630.1 CDS ylaC NC_008563.1 494509 495018 R hypothetical protein complement(494509..495018) Escherichia coli APEC O1 4494030 YP_851631.1 CDS maa NC_008563.1 495095 495646 R maltose O-acetyltransferase complement(495095..495646) Escherichia coli APEC O1 4494031 YP_851632.1 CDS hha NC_008563.1 495820 496239 R Hha protein complement(495820..496239) Escherichia coli APEC O1 4494032 YP_851633.1 CDS acrB NC_008563.1 496983 500132 R acridine efflux pump complement(496983..500132) Escherichia coli APEC O1 4494033 YP_851634.1 CDS acrA NC_008563.1 500155 501348 R acriflavine resistance protein A precursor complement(500155..501348) Escherichia coli APEC O1 4494034 YP_851635.1 CDS acrR NC_008563.1 501490 502137 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 501490..502137 Escherichia coli APEC O1 4494035 YP_851636.1 CDS kefA NC_008563.1 502265 505627 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 502265..505627 Escherichia coli APEC O1 4494036 YP_851637.1 CDS priC NC_008563.1 506014 506541 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(506014..506541) Escherichia coli APEC O1 4494037 YP_851638.1 CDS ybaN NC_008563.1 506611 506988 D hypothetical protein 506611..506988 Escherichia coli APEC O1 4494038 YP_851639.1 CDS apt NC_008563.1 507108 507692 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 507108..507692 Escherichia coli APEC O1 4494039 YP_851640.1 CDS dnaX NC_008563.1 507821 509752 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 507821..509752 Escherichia coli APEC O1 4494040 YP_851641.1 CDS APECO1_1544 NC_008563.1 509805 510134 D hypothetical protein 509805..510134 Escherichia coli APEC O1 4494041 YP_851642.1 CDS recR NC_008563.1 510134 510739 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 510134..510739 Escherichia coli APEC O1 4494042 YP_851643.1 CDS htpG NC_008563.1 510849 512723 D molecular chaperone; heat shock protein 90 510849..512723 Escherichia coli APEC O1 4493664 YP_851644.2 CDS adk NC_008563.1 512904 513548 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 512904..513548 Escherichia coli APEC O1 4493665 YP_851645.1 CDS hemH NC_008563.1 513680 514642 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 513680..514642 Escherichia coli APEC O1 4493666 YP_851646.1 CDS ybaC NC_008563.1 514639 515598 R acetyl esterase complement(514639..515598) Escherichia coli APEC O1 4493667 YP_851647.1 CDS gsk NC_008563.1 515750 517054 D inosine-guanosine kinase 515750..517054 Escherichia coli APEC O1 4493668 YP_851648.1 CDS ybaL NC_008563.1 517184 518860 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(517184..518860) Escherichia coli APEC O1 4493669 YP_851649.1 CDS fsr NC_008563.1 519099 520319 R fosmidomycin resistance protein complement(519099..520319) Escherichia coli APEC O1 4493670 YP_851650.1 CDS ushA NC_008563.1 520537 522189 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 520537..522189 Escherichia coli APEC O1 4493671 YP_851651.1 CDS APECO1_1534 NC_008563.1 522227 522730 R hypothetical protein complement(522227..522730) Escherichia coli APEC O1 4493672 YP_851652.1 CDS APECO1_1533 NC_008563.1 522727 523527 R hypothetical protein complement(522727..523527) Escherichia coli APEC O1 4493673 YP_851653.1 CDS ybaK NC_008563.1 523551 524030 R hypothetical protein complement(523551..524030) Escherichia coli APEC O1 4493674 YP_851654.1 CDS ybaP NC_008563.1 524234 525028 R ligase complement(524234..525028) Escherichia coli APEC O1 4493675 YP_851655.1 CDS APECO1_1530 NC_008563.1 525161 525463 D hypothetical protein 525161..525463 Escherichia coli APEC O1 4493676 YP_851656.1 CDS ybaQ NC_008563.1 525499 525840 D DNA-binding transcriptional regulator 525499..525840 Escherichia coli APEC O1 4493677 YP_851657.1 CDS copA NC_008563.1 525898 528402 R copper exporting ATPase complement(525898..528402) Escherichia coli APEC O1 4493678 YP_851658.1 CDS ybaS NC_008563.1 528664 529596 D catalyzes the formation of glutamate from glutamine; glutaminase 528664..529596 Escherichia coli APEC O1 4493679 YP_851659.1 CDS ybaT NC_008563.1 529599 530891 D transporter 529599..530891 Escherichia coli APEC O1 4493680 YP_851660.1 CDS ybbI NC_008563.1 531016 531423 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 531016..531423 Escherichia coli APEC O1 4493681 YP_851661.1 CDS APECO1_1524 NC_008563.1 531627 532049 R hypothetical protein complement(531627..532049) Escherichia coli APEC O1 4493682 YP_851662.1 CDS APECO1_1523 NC_008563.1 532135 533151 R adhesin/invasin-like protein complement(532135..533151) Escherichia coli APEC O1 4493683 YP_851663.1 CDS APECO1_1522 NC_008563.1 533518 533880 D hypothetical protein 533518..533880 Escherichia coli APEC O1 4493606 YP_851664.1 CDS ybbJ NC_008563.1 533983 534441 R hypothetical protein complement(533983..534441) Escherichia coli APEC O1 4493607 YP_851665.1 CDS ybbK NC_008563.1 534438 535355 R protease YbbK complement(534438..535355) Escherichia coli APEC O1 4493608 YP_851666.1 CDS ybbL NC_008563.1 535501 536178 D ABC transporter ATP-binding protein 535501..536178 Escherichia coli APEC O1 4493609 YP_851667.1 CDS ybbM NC_008563.1 536138 536944 D metal resistance protein 536138..536944 Escherichia coli APEC O1 4493610 YP_851668.1 CDS ybbN NC_008563.1 537007 537897 R thioredoxin complement(537007..537897) Escherichia coli APEC O1 4493611 YP_851669.1 CDS ybbO NC_008563.1 537922 538731 R short chain dehydrogenase complement(537922..538731) Escherichia coli APEC O1 4493612 YP_851670.1 CDS tesA NC_008563.1 538721 539377 R multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(538721..539377) Escherichia coli APEC O1 4493613 YP_851671.1 CDS ybbA NC_008563.1 539315 540001 D ABC transporter ATP-binding protein 539315..540001 Escherichia coli APEC O1 4493614 YP_851672.1 CDS ybbP NC_008563.1 539998 542412 D hypothetical protein 539998..542412 Escherichia coli APEC O1 4493615 YP_851673.1 CDS ybbB NC_008563.1 542471 543565 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(542471..543565) Escherichia coli APEC O1 4493616 YP_851674.1 CDS ybbS NC_008563.1 543634 544560 R activator of the allDC-ylbA operon involved in allantoin utilization; AllS family transcriptional regulator complement(543634..544560) Escherichia coli APEC O1 4493617 YP_851675.1 CDS allA NC_008563.1 544790 545272 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 544790..545272 Escherichia coli APEC O1 4493618 YP_851676.1 CDS ybbU NC_008563.1 545350 546165 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 545350..546165 Escherichia coli APEC O1 4493619 YP_851677.1 CDS gcl NC_008563.1 546165 548036 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 546165..548036 Escherichia coli APEC O1 4493620 YP_851678.1 CDS hyi NC_008563.1 548049 548825 D hydroxypyruvate isomerase 548049..548825 Escherichia coli APEC O1 4493621 YP_851679.1 CDS ybbQ NC_008563.1 548925 549803 D 2-hydroxy-3-oxopropionate reductase 548925..549803 Escherichia coli APEC O1 4493622 YP_851680.1 CDS ybbW NC_008563.1 549973 551427 D allantoin permease 549973..551427 Escherichia coli APEC O1 4493623 YP_851681.1 CDS allB NC_008563.1 551487 552848 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 551487..552848 Escherichia coli APEC O1 4493624 YP_851682.1 CDS ybbY NC_008563.1 552898 554205 D purine permease YbbY 552898..554205 Escherichia coli APEC O1 4494856 YP_851683.1 CDS glxK NC_008563.1 554227 555372 D glycerate kinase 554227..555372 Escherichia coli APEC O1 4494857 YP_851684.1 CDS ylbA NC_008563.1 555501 556286 R hypothetical protein complement(555501..556286) Escherichia coli APEC O1 4494858 YP_851685.1 CDS allC NC_008563.1 556297 557532 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(556297..557532) Escherichia coli APEC O1 4494859 YP_851686.1 CDS allD NC_008563.1 557554 558603 R ureidoglycolate dehydrogenase complement(557554..558603) Escherichia coli APEC O1 4494860 YP_851687.1 CDS fdrA NC_008563.1 558920 560587 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 558920..560587 Escherichia coli APEC O1 4494861 YP_851688.1 CDS ylbE NC_008563.1 560597 561856 D hypothetical protein 560597..561856 Escherichia coli APEC O1 4494862 YP_851689.1 CDS ylbF NC_008563.1 561867 562682 D hypothetical protein 561867..562682 Escherichia coli APEC O1 4494863 YP_851690.1 CDS arcC NC_008563.1 562679 563572 D carbamate kinase 562679..563572 Escherichia coli APEC O1 4494864 YP_851691.1 CDS purK NC_008563.1 563725 564792 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(563725..564792) Escherichia coli APEC O1 4494865 YP_851692.1 CDS purE NC_008563.1 564789 565298 R phosphoribosylaminoimidazole carboxylase catalytic subunit complement(564789..565298) Escherichia coli APEC O1 4494866 YP_851693.1 CDS APECO1_1491 NC_008563.1 565394 565723 R hypothetical protein complement(565394..565723) Escherichia coli APEC O1 4494867 YP_851694.1 CDS ybbF NC_008563.1 565834 566556 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(565834..566556) Escherichia coli APEC O1 4494868 YP_851696.1 CDS cysS NC_008563.1 567227 568612 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 567227..568612 Escherichia coli APEC O1 4494870 YP_851697.1 CDS APECO1_1487 NC_008563.1 568648 569169 R hypothetical protein complement(568648..569169) Escherichia coli APEC O1 4494871 YP_851698.1 CDS folD NC_008563.1 569491 570357 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(569491..570357) Escherichia coli APEC O1 4494872 YP_851699.1 CDS intD NC_008563.1 570712 571092 R prophage DLP12 integrase complement(570712..571092) Escherichia coli APEC O1 4494873 YP_851700.1 CDS intD NC_008563.1 571040 571447 R prophage DLP12 integrase complement(571040..571447) Escherichia coli APEC O1 4494874 YP_851701.1 CDS ybcY NC_008563.1 571757 572422 R hypothetical protein complement(571757..572422) Escherichia coli APEC O1 4493850 YP_851702.1 CDS ompT NC_008563.1 572657 573610 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(572657..573610) Escherichia coli APEC O1 4493851 YP_851703.1 CDS ybcH NC_008563.1 574268 575158 R hypothetical protein complement(574268..575158) Escherichia coli APEC O1 4493852 YP_851704.1 CDS nfrA NC_008563.1 575159 578131 R bacteriophage N4 receptor, outer membrane subunit complement(575159..578131) Escherichia coli APEC O1 4493853 YP_851705.1 CDS nfrB NC_008563.1 578118 580355 R bacteriophage N4 adsorption protein B complement(578118..580355) Escherichia coli APEC O1 4493854 YP_851706.1 CDS cusS NC_008563.1 580505 581947 R sensor kinase CusS complement(580505..581947) Escherichia coli APEC O1 4493855 YP_851707.1 CDS ylcA NC_008563.1 581937 582620 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; CusR family transcriptional regulator complement(581937..582620) Escherichia coli APEC O1 4493856 YP_851708.1 CDS cusC NC_008563.1 582777 584159 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 582777..584159 Escherichia coli APEC O1 4493857 YP_851709.1 CDS APECO1_1475 NC_008563.1 584183 584515 D copper-binding protein 584183..584515 Escherichia coli APEC O1 4493858 YP_851710.1 CDS cusB NC_008563.1 584531 585754 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 584531..585754 Escherichia coli APEC O1 4493859 YP_851711.1 CDS cusA NC_008563.1 585766 588909 D copper/silver efflux system, membrane component 585766..588909 Escherichia coli APEC O1 4493864 YP_851712.1 CDS pheP NC_008563.1 588975 590387 D phenylalanine transporter 588975..590387 Escherichia coli APEC O1 4493865 YP_851713.1 CDS ybdG NC_008563.1 590469 591716 R hypothetical protein complement(590469..591716) Escherichia coli APEC O1 4493866 YP_851714.1 CDS nfnB NC_008563.1 591824 592477 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(591824..592477) Escherichia coli APEC O1 4493867 YP_851715.1 CDS ybdF NC_008563.1 592556 592939 R hypothetical protein complement(592556..592939) Escherichia coli APEC O1 4493359 YP_851716.1 CDS ybdK NC_008563.1 593318 594436 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(593318..594436) Escherichia coli APEC O1 4493360 YP_851717.1 CDS APECO1_1467 NC_008563.1 594652 594921 R hypothetical protein complement(594652..594921) Escherichia coli APEC O1 4493361 YP_851718.1 CDS entD NC_008563.1 595164 595934 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(595164..595934) Escherichia coli APEC O1 4493362 YP_851719.2 CDS fepA NC_008563.1 596253 598199 R ferrienterobactin receptor complement(596253..598199) Escherichia coli APEC O1 4493363 YP_851720.1 CDS fes NC_008563.1 598442 599644 D enterobactin/ferric enterobactin esterase 598442..599644 Escherichia coli APEC O1 4493364 YP_851721.1 CDS entF NC_008563.1 599724 603743 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 599724..603743 Escherichia coli APEC O1 4493365 YP_851722.1 CDS fepE NC_008563.1 603839 605092 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 603839..605092 Escherichia coli APEC O1 4493366 YP_851723.1 CDS fepC NC_008563.1 605089 606222 R iron-enterobactin transporter ATP-binding protein complement(605089..606222) Escherichia coli APEC O1 4493367 YP_851724.1 CDS fepG NC_008563.1 605901 606893 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(605901..606893) Escherichia coli APEC O1 4493368 YP_851725.1 CDS fepD NC_008563.1 606890 607906 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(606890..607906) Escherichia coli APEC O1 4493369 YP_851726.1 CDS ybdA NC_008563.1 608005 609255 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 608005..609255 Escherichia coli APEC O1 4493370 YP_851727.1 CDS fepB NC_008563.1 609259 610215 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(609259..610215) Escherichia coli APEC O1 4493371 YP_851728.1 CDS entC NC_008563.1 610392 611579 D isochorismate synthase 610392..611579 Escherichia coli APEC O1 4493372 YP_851729.1 CDS entE NC_008563.1 611589 613199 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 611589..613199 Escherichia coli APEC O1 4493373 YP_851730.1 CDS entB NC_008563.1 613213 614070 D 2,3-dihydro-2,3-dihydroxybenzoate synthetase 613213..614070 Escherichia coli APEC O1 4493374 YP_851731.1 CDS entA NC_008563.1 614040 614816 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 614040..614816 Escherichia coli APEC O1 4493375 YP_851732.1 CDS APECO1_1452 NC_008563.1 614819 615232 D hypothetical protein 614819..615232 Escherichia coli APEC O1 4493376 YP_851733.1 CDS cstA NC_008563.1 615413 617518 D carbon starvation protein 615413..617518 Escherichia coli APEC O1 4493377 YP_851734.1 CDS ybdH NC_008563.1 617838 618926 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(617838..618926) Escherichia coli APEC O1 4493378 YP_851735.1 CDS ybdL NC_008563.1 618998 620206 D catalyzes the transfer of an amino moiety; aminotransferase 618998..620206 Escherichia coli APEC O1 4492932 YP_851736.1 CDS ybdM NC_008563.1 620207 620836 R hypothetical protein complement(620207..620836) Escherichia coli APEC O1 4492933 YP_851737.1 CDS ybdN NC_008563.1 620809 622029 R hypothetical protein complement(620809..622029) Escherichia coli APEC O1 4492934 YP_851738.1 CDS ybdO NC_008563.1 622176 623114 R transcriptional regulator YbdO complement(622176..623114) Escherichia coli APEC O1 4492935 YP_851739.1 CDS dsbG NC_008563.1 623283 624089 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(623283..624089) Escherichia coli APEC O1 4492936 YP_851740.1 CDS ahpC NC_008563.1 624401 624964 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 624401..624964 Escherichia coli APEC O1 4492937 YP_851741.1 CDS ahpF NC_008563.1 625105 626700 D alkyl hydroperoxide reductase subunit F 625105..626700 Escherichia coli APEC O1 4492938 YP_851742.1 CDS uspG NC_008563.1 626822 627283 R universal stress protein UspG complement(626822..627283) Escherichia coli APEC O1 4492939 YP_851743.1 CDS rnk NC_008563.1 627606 628016 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(627606..628016) Escherichia coli APEC O1 4492940 YP_851744.1 CDS rna NC_008563.1 628246 629070 R ribonuclease I complement(628246..629070) Escherichia coli APEC O1 4492941 YP_851745.1 CDS ybdS NC_008563.1 629166 630629 R citrate carrier/transporter complement(629166..630629) Escherichia coli APEC O1 4492942 YP_851746.1 CDS citG NC_008563.1 630680 631558 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(630680..631558) Escherichia coli APEC O1 4492943 YP_851747.1 CDS citX NC_008563.1 631533 632084 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(631533..632084) Escherichia coli APEC O1 4492944 YP_851748.1 CDS citF NC_008563.1 632088 633662 R citrate lyase subunit alpha complement(632088..633662) Escherichia coli APEC O1 4492945 YP_851749.1 CDS citE NC_008563.1 633631 634554 R citrate lyase subunit beta complement(633631..634554) Escherichia coli APEC O1 4492946 YP_851750.1 CDS citC NC_008563.1 634847 635992 R citrate lyase synthetase complement(634847..635992) Escherichia coli APEC O1 4492947 YP_851751.1 CDS dpiB NC_008563.1 636284 637942 D sensor kinase DpiB 636284..637942 Escherichia coli APEC O1 4492948 YP_851752.1 CDS dpiA NC_008563.1 637911 638591 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 637911..638591 Escherichia coli APEC O1 4492949 YP_851753.1 CDS dcuC NC_008563.1 638632 640017 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(638632..640017) Escherichia coli APEC O1 4492950 YP_851754.1 CDS pagP NC_008563.1 640604 641164 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 640604..641164 Escherichia coli APEC O1 4494290 YP_851755.1 CDS crcB NC_008563.1 641602 641985 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(641602..641985) Escherichia coli APEC O1 4494291 YP_851756.1 CDS ybeM NC_008563.1 642075 642869 D amidase 642075..642869 Escherichia coli APEC O1 4494292 YP_851757.1 CDS lipA NC_008563.1 643301 644266 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(643301..644266) Escherichia coli APEC O1 4494293 YP_851758.1 CDS APECO1_1426 NC_008563.1 644485 644826 R hypothetical protein complement(644485..644826) Escherichia coli APEC O1 4494294 YP_851759.1 CDS lipB NC_008563.1 645086 645661 R lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase complement(645086..645661) Escherichia coli APEC O1 4494295 YP_851760.1 CDS APECO1_1424 NC_008563.1 645828 646091 R hypothetical protein complement(645828..646091) Escherichia coli APEC O1 4494296 YP_851761.1 CDS dacA NC_008563.1 646201 647412 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(646201..647412) Escherichia coli APEC O1 4494297 YP_851762.1 CDS rlpA NC_008563.1 647552 648889 R rare lipoprotein A complement(647552..648889) Escherichia coli APEC O1 4494298 YP_851763.1 CDS mrdB NC_008563.1 648652 649764 R cell wall shape-determining protein complement(648652..649764) Escherichia coli APEC O1 4494299 YP_851764.1 CDS pbpA NC_008563.1 649767 651668 R penicillin-binding protein 2 complement(649767..651668) Escherichia coli APEC O1 4494300 YP_851765.1 CDS APECO1_1419 NC_008563.1 651699 652166 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(651699..652166) Escherichia coli APEC O1 4494301 YP_851766.1 CDS APECO1_1418 NC_008563.1 652501 652791 D hypothetical protein 652501..652791 Escherichia coli APEC O1 4494302 YP_851767.1 CDS phpB NC_008563.1 652747 653361 R alpha-ribazole-5'-phosphate phosphatase complement(652747..653361) Escherichia coli APEC O1 4494303 YP_851768.1 CDS nadD NC_008563.1 653382 654023 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(653382..654023) Escherichia coli APEC O1 4494304 YP_851769.1 CDS holA NC_008563.1 654025 655056 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(654025..655056) Escherichia coli APEC O1 4494305 YP_851770.1 CDS rlpB NC_008563.1 655056 655637 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(655056..655637) Escherichia coli APEC O1 4494306 YP_851771.1 CDS leuS NC_008563.1 655652 658375 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(655652..658375) Escherichia coli APEC O1 4494307 YP_851772.1 CDS ybeL NC_008563.1 658469 658951 D hypothetical protein 658469..658951 Escherichia coli APEC O1 4494308 YP_851773.1 CDS rihA NC_008563.1 658996 659931 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(658996..659931) Escherichia coli APEC O1 4494309 YP_851774.1 CDS gltL NC_008563.1 660049 660774 R glutamate/aspartate ABC transporter ATP-binding protein complement(660049..660774) Escherichia coli APEC O1 4492387 YP_851775.1 CDS gltK NC_008563.1 660774 661448 R glutamate/aspartate transport system permease complement(660774..661448) Escherichia coli APEC O1 4492388 YP_851776.1 CDS gltJ NC_008563.1 661448 662188 R glutamate and aspartate transporter subunit complement(661448..662188) Escherichia coli APEC O1 4492389 YP_851777.1 CDS ybeJ NC_008563.1 662358 663335 R glutamate and aspartate transporter subunit complement(662358..663335) Escherichia coli APEC O1 4492390 YP_851778.1 CDS APECO1_1407 NC_008563.1 663720 665597 D hypothetical protein 663720..665597 Escherichia coli APEC O1 4492391 YP_851779.1 CDS lnt NC_008563.1 665724 667265 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(665724..667265) Escherichia coli APEC O1 4492392 YP_851780.1 CDS ybeX NC_008563.1 667290 668168 R transporter complement(667290..668168) Escherichia coli APEC O1 4492393 YP_851781.1 CDS APECO1_1404 NC_008563.1 668258 668725 R metalloprotease complement(668258..668725) Escherichia coli APEC O1 4492394 YP_851782.1 CDS ybeZ NC_008563.1 668722 669801 R ATP-binding protein in pho regulon complement(668722..669801) Escherichia coli APEC O1 4492395 YP_851783.1 CDS miaB NC_008563.1 669915 671339 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(669915..671339) Escherichia coli APEC O1 4492396 YP_851784.1 CDS ubiF NC_008563.1 671485 672660 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 671485..672660 Escherichia coli APEC O1 4492397 YP_851787.1 CDS asnB NC_008563.1 673901 675799 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(673901..675799) Escherichia coli APEC O1 4492400 YP_851788.1 CDS nagD NC_008563.1 675821 676573 R UMP phosphatase complement(675821..676573) Escherichia coli APEC O1 4492401 YP_851789.1 CDS nagC NC_008563.1 676621 677841 R transcriptional repressor of nag complement(676621..677841) Escherichia coli APEC O1 4492402 YP_851790.1 CDS nagA NC_008563.1 677850 678998 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(677850..678998) Escherichia coli APEC O1 4492403 YP_851791.1 CDS nagB NC_008563.1 679058 679858 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(679058..679858) Escherichia coli APEC O1 4492404 YP_851792.1 CDS nagE NC_008563.1 680191 682137 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 680191..682137 Escherichia coli APEC O1 4492405 YP_851793.1 CDS APECO1_1392 NC_008563.1 682226 683752 R hypothetical protein complement(682226..683752) Escherichia coli APEC O1 4492278 YP_851794.1 CDS APECO1_1391 NC_008563.1 683987 685156 R hypothetical protein complement(683987..685156) Escherichia coli APEC O1 4492279 YP_851795.1 CDS APECO1_1390 NC_008563.1 685221 685742 R hypothetical protein complement(685221..685742) Escherichia coli APEC O1 4492280 YP_851796.1 CDS APECO1_1389 NC_008563.1 686002 686889 R dihydrodipicolinate synthase complement(686002..686889) Escherichia coli APEC O1 4492281 YP_851797.1 CDS APECO1_1388 NC_008563.1 686893 688050 R alcohol dehydrogenase complement(686893..688050) Escherichia coli APEC O1 4492282 YP_851798.1 CDS APECO1_1387 NC_008563.1 688214 689455 D hypothetical protein 688214..689455 Escherichia coli APEC O1 4492283 YP_851799.1 CDS pdxA NC_008563.1 689448 690434 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 689448..690434 Escherichia coli APEC O1 4492284 YP_851800.1 CDS APECO1_1385 NC_008563.1 690436 691197 D transcriptional regulator 690436..691197 Escherichia coli APEC O1 4492285 YP_851801.1 CDS glnS NC_008563.1 691417 693081 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 691417..693081 Escherichia coli APEC O1 4492286 YP_851802.1 CDS ybfM NC_008563.1 693530 694936 D hypothetical protein 693530..694936 Escherichia coli APEC O1 4492287 YP_851803.1 CDS ybfN NC_008563.1 694986 695312 D lipoprotein ybfN precursor 694986..695312 Escherichia coli APEC O1 4492288 YP_851804.1 CDS fur NC_008563.1 695396 695842 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(695396..695842) Escherichia coli APEC O1 4492289 YP_851805.1 CDS fldA NC_008563.1 696131 696778 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(696131..696778) Escherichia coli APEC O1 4492290 YP_851806.1 CDS ybfE NC_008563.1 696801 697163 R LexA regulated protein complement(696801..697163) Escherichia coli APEC O1 4493477 YP_851807.1 CDS ybfF NC_008563.1 697234 697998 R hypothetical protein complement(697234..697998) Escherichia coli APEC O1 4493478 YP_851808.1 CDS seqA NC_008563.1 698183 698728 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 698183..698728 Escherichia coli APEC O1 4493479 YP_851809.1 CDS pgm NC_008563.1 698754 700394 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 698754..700394 Escherichia coli APEC O1 4493480 YP_851810.1 CDS potE NC_008563.1 700451 701770 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(700451..701770) Escherichia coli APEC O1 4493481 YP_851811.1 CDS speF NC_008563.1 701767 703974 R ornithine decarboxylase complement(701767..703974) Escherichia coli APEC O1 4493482 YP_851812.1 CDS kdpE NC_008563.1 704654 705331 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(704654..705331) Escherichia coli APEC O1 4493483 YP_851813.1 CDS kdpD NC_008563.1 705328 708012 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(705328..708012) Escherichia coli APEC O1 4493484 YP_851814.1 CDS kdpC NC_008563.1 708005 708589 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(708005..708589) Escherichia coli APEC O1 4493485 YP_851815.1 CDS kdpB NC_008563.1 708586 710634 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(708586..710634) Escherichia coli APEC O1 4493486 YP_851816.1 CDS kdpA NC_008563.1 710657 712426 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(710657..712426) Escherichia coli APEC O1 4493487 YP_851817.1 CDS ybgA NC_008563.1 713039 713548 D hypothetical protein 713039..713548 Escherichia coli APEC O1 4493488 YP_851818.1 CDS phrB NC_008563.1 713545 714963 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 713545..714963 Escherichia coli APEC O1 4493489 YP_851819.1 CDS ybgH NC_008563.1 715005 716486 R hypothetical protein complement(715005..716486) Escherichia coli APEC O1 4493490 YP_851820.1 CDS ybgI NC_008563.1 716757 717500 D hydrolase-oxidase 716757..717500 Escherichia coli APEC O1 4493491 YP_851821.1 CDS ybgJ NC_008563.1 717523 718179 D hypothetical protein 717523..718179 Escherichia coli APEC O1 4493492 YP_851822.1 CDS ybgK NC_008563.1 718173 719105 D hypothetical protein 718173..719105 Escherichia coli APEC O1 4493493 YP_851823.1 CDS ybgL NC_008563.1 719095 719829 D LamB/YcsF family protein 719095..719829 Escherichia coli APEC O1 4493494 YP_851824.1 CDS nei NC_008563.1 719865 720656 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 719865..720656 Escherichia coli APEC O1 4493495 YP_851825.1 CDS abrB NC_008563.1 720653 721744 R transport protein AbrB complement(720653..721744) Escherichia coli APEC O1 4494310 YP_851826.1 CDS ybgO NC_008563.1 721851 722225 R hypothetical protein complement(721851..722225) Escherichia coli APEC O1 4494311 YP_851827.1 CDS gltA NC_008563.1 722373 723656 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(722373..723656) Escherichia coli APEC O1 4494312 YP_851828.1 CDS sdhC NC_008563.1 724350 724754 D succinate dehydrogenase cytochrome b556 large membrane subunit 724350..724754 Escherichia coli APEC O1 4494313 YP_851829.1 CDS sdhD NC_008563.1 724748 725095 D succinate dehydrogenase cytochrome b556 small membrane subunit 724748..725095 Escherichia coli APEC O1 4494314 YP_851830.1 CDS sdhA NC_008563.1 725083 726861 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 725083..726861 Escherichia coli APEC O1 4494315 YP_851831.1 CDS sdhB NC_008563.1 726877 727593 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 726877..727593 Escherichia coli APEC O1 4494318 YP_851832.1 CDS sucA NC_008563.1 727954 730755 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 727954..730755 Escherichia coli APEC O1 4494319 YP_851833.1 CDS sucB NC_008563.1 730770 731987 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 730770..731987 Escherichia coli APEC O1 4494320 YP_851834.1 CDS sucC NC_008563.1 732081 733247 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 732081..733247 Escherichia coli APEC O1 4494321 YP_851835.1 CDS sucD NC_008563.1 733247 734116 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 733247..734116 Escherichia coli APEC O1 4494322 YP_851836.1 CDS APECO1_1349 NC_008563.1 734356 735471 D hypothetical protein 734356..735471 Escherichia coli APEC O1 4494323 YP_851837.1 CDS cydA NC_008563.1 736798 738369 D cytochrome d terminal oxidase, subunit I 736798..738369 Escherichia coli APEC O1 4494324 YP_851839.1 CDS APECO1_1346 NC_008563.1 739652 739945 D hypothetical protein 739652..739945 Escherichia coli APEC O1 4494326 YP_851840.1 CDS APECO1_1345 NC_008563.1 740095 740499 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 740095..740499 Escherichia coli APEC O1 4494327 YP_851841.1 CDS tolQ NC_008563.1 740496 741188 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 740496..741188 Escherichia coli APEC O1 4494328 YP_851842.1 CDS APECO1_1343 NC_008563.1 741192 741620 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 741192..741620 Escherichia coli APEC O1 4494329 YP_851843.1 CDS tolA NC_008563.1 741685 742935 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 741685..742935 Escherichia coli APEC O1 4495308 YP_851844.1 CDS tolB NC_008563.1 743065 744360 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 743065..744360 Escherichia coli APEC O1 4495309 YP_851845.1 CDS pal NC_008563.1 744395 744916 D peptidoglycan-associated outer membrane lipoprotein 744395..744916 Escherichia coli APEC O1 4495310 YP_851846.1 CDS ybgF NC_008563.1 744926 745717 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 744926..745717 Escherichia coli APEC O1 4495311 YP_851847.1 CDS nadA NC_008563.1 746863 747906 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 746863..747906 Escherichia coli APEC O1 4495312 YP_851848.1 CDS pnuC NC_008563.1 747944 748663 D hypothetical protein 747944..748663 Escherichia coli APEC O1 4495313 YP_851849.1 CDS ybgR NC_008563.1 748660 749601 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(748660..749601) Escherichia coli APEC O1 4495314 YP_851850.1 CDS ybgS NC_008563.1 749715 750095 R hypothetical protein complement(749715..750095) Escherichia coli APEC O1 4495315 YP_851851.1 CDS aroG NC_008563.1 750411 751463 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 750411..751463 Escherichia coli APEC O1 4495316 YP_851852.1 CDS gpmA NC_008563.1 751630 752382 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(751630..752382) Escherichia coli APEC O1 4495317 YP_851853.1 CDS galM NC_008563.1 752585 753625 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(752585..753625) Escherichia coli APEC O1 4495318 YP_851854.1 CDS galK NC_008563.1 753619 754767 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(753619..754767) Escherichia coli APEC O1 4495319 YP_851855.1 CDS galT NC_008563.1 754771 755817 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(754771..755817) Escherichia coli APEC O1 4495320 YP_851856.1 CDS galE NC_008563.1 755827 756885 R UDP-galactose-4-epimerase complement(755827..756885) Escherichia coli APEC O1 4495321 YP_851857.2 CDS modF NC_008563.1 757106 758578 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(757106..758578) Escherichia coli APEC O1 4495322 YP_851858.1 CDS modE NC_008563.1 758646 759434 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(758646..759434) Escherichia coli APEC O1 4495323 YP_851859.1 CDS modA NC_008563.1 759879 760652 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 759879..760652 Escherichia coli APEC O1 4495324 YP_851860.1 CDS modB NC_008563.1 760652 761341 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 760652..761341 Escherichia coli APEC O1 4495325 YP_851861.1 CDS modC NC_008563.1 761344 762402 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 761344..762402 Escherichia coli APEC O1 4495326 YP_851862.1 CDS yghA NC_008563.1 762403 763317 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(762403..763317) Escherichia coli APEC O1 4493438 YP_851863.1 CDS ybhE NC_008563.1 763376 764371 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 763376..764371 Escherichia coli APEC O1 4493439 YP_851864.1 CDS ybhD NC_008563.1 764412 765428 R DNA-binding transcriptional regulator complement(764412..765428) Escherichia coli APEC O1 4493440 YP_851865.1 CDS APECO1_1320 NC_008563.1 765549 766601 D hypothetical protein 765549..766601 Escherichia coli APEC O1 4493441 YP_851866.1 CDS ybhI NC_008563.1 766677 768110 D hypothetical protein 766677..768110 Escherichia coli APEC O1 4493442 YP_851867.1 CDS ybhJ NC_008563.1 768269 770554 D hypothetical protein 768269..770554 Escherichia coli APEC O1 4493443 YP_851868.1 CDS ybhC NC_008563.1 770695 771978 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase complement(770695..771978) Escherichia coli APEC O1 4493444 YP_851869.1 CDS ybhB NC_008563.1 772130 772606 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(772130..772606) Escherichia coli APEC O1 4493445 YP_851870.1 CDS bioA NC_008563.1 772665 773954 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(772665..773954) Escherichia coli APEC O1 4493446 YP_851871.1 CDS bioB NC_008563.1 774042 775082 D biotin synthase 774042..775082 Escherichia coli APEC O1 4493447 YP_851872.1 CDS bioF NC_008563.1 775079 776233 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 775079..776233 Escherichia coli APEC O1 4493448 YP_851873.2 CDS bioC NC_008563.1 776220 776975 D methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 776220..776975 Escherichia coli APEC O1 4493449 YP_851874.1 CDS bioD NC_008563.1 776968 777645 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 776968..777645 Escherichia coli APEC O1 4493450 YP_851875.1 CDS uvrB NC_008563.1 778224 780245 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 778224..780245 Escherichia coli APEC O1 4493451 YP_851876.1 CDS ybhK NC_008563.1 780283 781191 R hypothetical protein complement(780283..781191) Escherichia coli APEC O1 4493452 YP_851877.1 CDS moaA NC_008563.1 781513 782577 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 781513..782577 Escherichia coli APEC O1 4493453 YP_851878.1 CDS moaB NC_008563.1 782599 783111 D molybdopterin biosynthesis, protein B 782599..783111 Escherichia coli APEC O1 4493454 YP_851879.1 CDS moaC NC_008563.1 783114 783599 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 783114..783599 Escherichia coli APEC O1 4493455 YP_851880.1 CDS moaE NC_008563.1 783839 784291 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 783839..784291 Escherichia coli APEC O1 4493456 YP_851881.1 CDS ybhL NC_008563.1 784428 785132 D hypothetical protein 784428..785132 Escherichia coli APEC O1 4493457 YP_851882.1 CDS ybhM NC_008563.1 785311 786051 D hypothetical protein 785311..786051 Escherichia coli APEC O1 4492329 YP_851883.1 CDS ybhN NC_008563.1 786087 787043 R hypothetical protein complement(786087..787043) Escherichia coli APEC O1 4492330 YP_851884.1 CDS ybhO NC_008563.1 787043 788284 R cardiolipin synthase 2 complement(787043..788284) Escherichia coli APEC O1 4492331 YP_851885.1 CDS APECO1_1300 NC_008563.1 788281 789042 R metal-dependent hydrolase complement(788281..789042) Escherichia coli APEC O1 4492332 YP_851886.1 CDS ybhQ NC_008563.1 789175 789585 D hypothetical protein 789175..789585 Escherichia coli APEC O1 4492333 YP_851887.1 CDS ybhR NC_008563.1 789547 790653 R hypothetical protein complement(789547..790653) Escherichia coli APEC O1 4492334 YP_851888.1 CDS ybhS NC_008563.1 790664 791797 R hypothetical protein complement(790664..791797) Escherichia coli APEC O1 4492335 YP_851889.1 CDS ybhF NC_008563.1 791790 793541 R ABC transporter complement(791790..793541) Escherichia coli APEC O1 4492336 YP_851890.1 CDS ybhG NC_008563.1 793519 794517 R hypothetical protein complement(793519..794517) Escherichia coli APEC O1 4492337 YP_851891.1 CDS ybiH NC_008563.1 794517 795200 R DNA-binding transcriptional regulator complement(794517..795200) Escherichia coli APEC O1 4492338 YP_851892.1 CDS rhlE NC_008563.1 795417 796778 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 795417..796778 Escherichia coli APEC O1 4492339 YP_851893.1 CDS APECO1_1292 NC_008563.1 797011 797316 R hypothetical protein complement(797011..797316) Escherichia coli APEC O1 4492340 YP_851894.1 CDS dinG NC_008563.1 797315 799465 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 797315..799465 Escherichia coli APEC O1 4492341 YP_851895.1 CDS ybiB NC_008563.1 799493 800455 D glycosyl transferase family protein 799493..800455 Escherichia coli APEC O1 4492342 YP_851896.1 CDS ybiC NC_008563.1 800596 801681 D hypothetical protein 800596..801681 Escherichia coli APEC O1 4492343 YP_851898.1 CDS ybiX NC_008563.1 802774 803487 R hydroxylase complement(802774..803487) Escherichia coli APEC O1 4492345 YP_851899.1 CDS ybiL NC_008563.1 803667 805949 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(803667..805949) Escherichia coli APEC O1 4492346 YP_851900.1 CDS ybiM NC_008563.1 806214 806621 R hypothetical protein complement(806214..806621) Escherichia coli APEC O1 4492347 YP_851901.1 CDS ybiN NC_008563.1 806660 807676 D SAM-dependent methyltransferase 806660..807676 Escherichia coli APEC O1 4494605 YP_851902.1 CDS ybiO NC_008563.1 807673 809898 R hypothetical protein complement(807673..809898) Escherichia coli APEC O1 4494608 YP_851903.1 CDS glnQ NC_008563.1 810015 810737 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(810015..810737) Escherichia coli APEC O1 4494609 YP_851904.1 CDS glnP NC_008563.1 810734 811393 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(810734..811393) Escherichia coli APEC O1 4494610 YP_851905.1 CDS glnH NC_008563.1 811532 812278 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(811532..812278) Escherichia coli APEC O1 4494611 YP_851906.1 CDS dps NC_008563.1 812682 813278 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(812682..813278) Escherichia coli APEC O1 4494612 YP_851907.1 CDS ybiF NC_008563.1 813484 814383 R threonine and homoserine efflux system complement(813484..814383) Escherichia coli APEC O1 4494613 YP_851908.1 CDS ompX NC_008563.1 814718 815239 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 814718..815239 Escherichia coli APEC O1 4494614 YP_851909.1 CDS ybiP NC_008563.1 815289 816872 R hypothetical protein complement(815289..816872) Escherichia coli APEC O1 4494615 YP_851910.1 CDS mntR NC_008563.1 817458 817925 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 817458..817925 Escherichia coli APEC O1 4494616 YP_851911.1 CDS ybiR NC_008563.1 817922 819040 D hypothetical protein 817922..819040 Escherichia coli APEC O1 4494617 YP_851912.1 CDS ybiS NC_008563.1 819098 820018 R hypothetical protein complement(819098..820018) Escherichia coli APEC O1 4494618 YP_851913.1 CDS ybiT NC_008563.1 820237 821829 D ATP-binding component of a transport system 820237..821829 Escherichia coli APEC O1 4494619 YP_851914.1 CDS ybiV NC_008563.1 822029 822844 R hypothetical protein complement(822029..822844) Escherichia coli APEC O1 4494620 YP_851915.1 CDS ybiW NC_008563.1 822990 825422 R formate acetyltransferase 3 complement(822990..825422) Escherichia coli APEC O1 4494621 YP_851916.1 CDS ybiY NC_008563.1 825428 826327 R pyruvate formate lyase activating enzyme complement(825428..826327) Escherichia coli APEC O1 4494622 YP_851917.2 CDS APECO1_1268 NC_008563.1 826458 827120 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 826458..827120 Escherichia coli APEC O1 4494658 YP_851918.1 CDS moeB NC_008563.1 827196 827945 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(827196..827945) Escherichia coli APEC O1 4494659 YP_851919.1 CDS moeA NC_008563.1 827945 829180 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(827945..829180) Escherichia coli APEC O1 4494660 YP_851920.1 CDS iaaA NC_008563.1 829384 830349 D L-asparaginase 829384..830349 Escherichia coli APEC O1 4494661 YP_851921.1 CDS yliA NC_008563.1 830228 832207 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 830228..832207 Escherichia coli APEC O1 4494662 YP_851922.1 CDS yliB NC_008563.1 831819 832937 D peptide transporter periplasmic-binding protein 831819..832937 Escherichia coli APEC O1 4494663 YP_851923.1 CDS yliB NC_008563.1 832921 833766 D peptide transporter periplasmic-binding protein 832921..833766 Escherichia coli APEC O1 4494664 YP_851924.1 CDS yliC NC_008563.1 833784 834704 D peptide transporter membrane protein 833784..834704 Escherichia coli APEC O1 4494665 YP_851925.1 CDS yliD NC_008563.1 834707 835618 D peptide transporter membrane protein 834707..835618 Escherichia coli APEC O1 4494666 YP_851926.1 CDS yliE NC_008563.1 835795 838143 D hypothetical protein 835795..838143 Escherichia coli APEC O1 4494667 YP_851927.1 CDS yliF NC_008563.1 838151 839479 D diguanylate cyclase 838151..839479 Escherichia coli APEC O1 4494668 YP_851928.1 CDS rimO NC_008563.1 839526 840851 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(839526..840851) Escherichia coli APEC O1 4494669 YP_851929.1 CDS bssR NC_008563.1 841064 841447 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 841064..841447 Escherichia coli APEC O1 4494670 YP_851930.1 CDS yliI NC_008563.1 841558 842673 D dehydrogenase 841558..842673 Escherichia coli APEC O1 4494673 YP_851931.1 CDS yliJ NC_008563.1 842670 843302 R glutathione S-transferase complement(842670..843302) Escherichia coli APEC O1 4494674 YP_851932.1 CDS dacC NC_008563.1 843522 844745 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 843522..844745 Escherichia coli APEC O1 4494675 YP_851933.1 CDS deoR NC_008563.1 844792 845550 R DNA-binding transcriptional repressor DeoR complement(844792..845550) Escherichia coli APEC O1 4494676 YP_851934.1 CDS ybjG NC_008563.1 845608 846204 R undecaprenyl pyrophosphate phosphatase complement(845608..846204) Escherichia coli APEC O1 4492952 YP_851935.1 CDS cmr NC_008563.1 846489 847721 D proton motive force efflux pump 846489..847721 Escherichia coli APEC O1 4492953 YP_851936.1 CDS ybjH NC_008563.1 847762 848028 R hypothetical protein complement(847762..848028) Escherichia coli APEC O1 4492954 YP_851937.1 CDS ybjI NC_008563.1 848113 848928 R hypothetical protein complement(848113..848928) Escherichia coli APEC O1 4492955 YP_851938.1 CDS ybjJ NC_008563.1 848928 850136 R DEOR-type transcriptional regulator complement(848928..850136) Escherichia coli APEC O1 4492956 YP_851939.1 CDS ybjK NC_008563.1 850220 850756 D DEOR-type transcriptional regulator 850220..850756 Escherichia coli APEC O1 4492957 YP_851940.1 CDS APECO1_1246 NC_008563.1 850931 852616 R hypothetical protein complement(850931..852616) Escherichia coli APEC O1 4492958 YP_851941.1 CDS ybjM NC_008563.1 852886 853263 D hypothetical protein 852886..853263 Escherichia coli APEC O1 4492959 YP_851942.1 CDS grxA NC_008563.1 853293 853565 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(853293..853565) Escherichia coli APEC O1 4492960 YP_851943.1 CDS ybjC NC_008563.1 853710 853997 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 853710..853997 Escherichia coli APEC O1 4492961 YP_851944.1 CDS nfsA NC_008563.1 853981 854703 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 853981..854703 Escherichia coli APEC O1 4492962 YP_851945.1 CDS rimK NC_008563.1 854764 855666 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 854764..855666 Escherichia coli APEC O1 4492963 YP_851946.1 CDS ybjN NC_008563.1 855754 856230 D hypothetical protein 855754..856230 Escherichia coli APEC O1 4492964 YP_851947.1 CDS potF NC_008563.1 856436 857692 D putrescine ABC transporter periplasmic-binding protein 856436..857692 Escherichia coli APEC O1 4492965 YP_851948.1 CDS potG NC_008563.1 857706 858920 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 857706..858920 Escherichia coli APEC O1 4492966 YP_851949.1 CDS potH NC_008563.1 858930 859883 D putrescine ABC transporter membrane protein 858930..859883 Escherichia coli APEC O1 4492967 YP_851950.1 CDS potI NC_008563.1 859838 860725 D putrescine ABC transporter membrane protein 859838..860725 Escherichia coli APEC O1 4492968 YP_851951.1 CDS APECO1_1235 NC_008563.1 860785 861273 D hypothetical protein 860785..861273 Escherichia coli APEC O1 4492969 YP_851952.1 CDS rumB NC_008563.1 861314 862441 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 861314..862441 Escherichia coli APEC O1 4492970 YP_851953.1 CDS artJ NC_008563.1 862470 863252 R arginine/ornithine ABC transporter substrate-binding protein complement(862470..863252) Escherichia coli APEC O1 4493302 YP_851954.1 CDS artM NC_008563.1 863427 864095 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(863427..864095) Escherichia coli APEC O1 4493303 YP_851955.1 CDS artQ NC_008563.1 864095 864811 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(864095..864811) Escherichia coli APEC O1 4493304 YP_851956.1 CDS artI NC_008563.1 864818 865549 R arginine transporter subunit complement(864818..865549) Escherichia coli APEC O1 4493305 YP_851957.1 CDS artP NC_008563.1 865567 866301 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(865567..866301) Escherichia coli APEC O1 4493306 YP_851958.1 CDS ybjP NC_008563.1 866513 866899 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(866513..866899) Escherichia coli APEC O1 4493307 YP_851959.1 CDS APECO1_1227 NC_008563.1 867153 867476 D hypothetical protein 867153..867476 Escherichia coli APEC O1 4493308 YP_851960.1 CDS ybjR NC_008563.1 867473 868303 D N-acetylmuramoyl-L-alanine amidase YbjR 867473..868303 Escherichia coli APEC O1 4493309 YP_851961.1 CDS ybjS NC_008563.1 869412 870905 R hypothetical protein complement(869412..870905) Escherichia coli APEC O1 4493310 YP_851962.1 CDS ybjU NC_008563.1 870853 871854 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(870853..871854) Escherichia coli APEC O1 4493311 YP_851963.1 CDS poxB NC_008563.1 871891 873609 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(871891..873609) Escherichia coli APEC O1 4493312 YP_851964.1 CDS hcr NC_008563.1 873742 874710 R HCP oxidoreductase complement(873742..874710) Escherichia coli APEC O1 4493313 YP_851965.1 CDS hcp NC_008563.1 874722 876380 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(874722..876380) Escherichia coli APEC O1 4493314 YP_851966.1 CDS ybjE NC_008563.1 876518 877462 R hypothetical protein complement(876518..877462) Escherichia coli APEC O1 4493315 YP_851967.1 CDS aqpZ NC_008563.1 877738 878439 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(877738..878439) Escherichia coli APEC O1 4493316 YP_851968.1 CDS ybjD NC_008563.1 878859 880517 D hypothetical protein 878859..880517 Escherichia coli APEC O1 4493317 YP_851969.1 CDS ybjX NC_008563.1 880514 881506 R hypothetical protein complement(880514..881506) Escherichia coli APEC O1 4493318 YP_851970.1 CDS macA NC_008563.1 881621 882736 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 881621..882736 Escherichia coli APEC O1 4493319 YP_851971.1 CDS ybjZ NC_008563.1 882733 884679 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 882733..884679 Escherichia coli APEC O1 4493320 YP_851972.1 CDS clpS NC_008563.1 885299 885619 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 885299..885619 Escherichia coli APEC O1 4491889 YP_851973.1 CDS clpA NC_008563.1 885644 887926 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 885644..887926 Escherichia coli APEC O1 4491890 YP_851974.1 CDS APECO1_1212 NC_008563.1 888044 888316 R hypothetical protein complement(888044..888316) Escherichia coli APEC O1 4491891 YP_851975.1 CDS APECO1_1211 NC_008563.1 888633 889622 D hypothetical protein 888633..889622 Escherichia coli APEC O1 4491892 YP_851976.1 CDS APECO1_1210 NC_008563.1 889619 892852 D hypothetical protein 889619..892852 Escherichia coli APEC O1 4491893 YP_851977.1 CDS APECO1_1209 NC_008563.1 893182 894489 D hypothetical protein 893182..894489 Escherichia coli APEC O1 4491894 YP_851978.1 CDS APECO1_1208 NC_008563.1 894768 895409 D hypothetical protein 894768..895409 Escherichia coli APEC O1 4491895 YP_851979.1 CDS APECO1_1207 NC_008563.1 895420 896421 D hypothetical protein 895420..896421 Escherichia coli APEC O1 4491896 YP_851980.1 CDS APECO1_1206 NC_008563.1 896390 896986 D hypothetical protein 896390..896986 Escherichia coli APEC O1 4491897 YP_851981.1 CDS APECO1_1205 NC_008563.1 897554 897874 D hypothetical protein 897554..897874 Escherichia coli APEC O1 4491898 YP_851982.1 CDS aat NC_008563.1 898531 899235 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(898531..899235) Escherichia coli APEC O1 4491899 YP_851983.1 CDS cydC NC_008563.1 899277 900998 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(899277..900998) Escherichia coli APEC O1 4491900 YP_851984.1 CDS cydD NC_008563.1 900999 902765 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(900999..902765) Escherichia coli APEC O1 4491901 YP_851985.1 CDS trxB NC_008563.1 902888 903958 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(902888..903958) Escherichia coli APEC O1 4491902 YP_851986.1 CDS lrp NC_008563.1 904343 904891 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 904343..904891 Escherichia coli APEC O1 4491903 YP_851987.1 CDS ftsK NC_008563.1 905137 909069 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 905137..909069 Escherichia coli APEC O1 4491904 YP_851988.1 CDS lolA NC_008563.1 909225 909839 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 909225..909839 Escherichia coli APEC O1 4491905 YP_851989.1 CDS ycaJ NC_008563.1 909850 911193 D recombination factor protein RarA 909850..911193 Escherichia coli APEC O1 4491906 YP_851990.1 CDS serS NC_008563.1 911284 912576 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 911284..912576 Escherichia coli APEC O1 4491907 YP_851991.1 CDS dmsA NC_008563.1 912815 915259 D anaerobic dimethyl sulfoxide reductase subunit A 912815..915259 Escherichia coli APEC O1 4491908 YP_851992.1 CDS dmsB NC_008563.1 915270 915887 D anaerobic dimethyl sulfoxide reductase subunit B 915270..915887 Escherichia coli APEC O1 4491401 YP_851993.1 CDS dmsC NC_008563.1 915826 916752 D anaerobic dimethyl sulfoxide reductase subunit C 915826..916752 Escherichia coli APEC O1 4491402 YP_851994.1 CDS ycaC NC_008563.1 916788 917513 R hypothetical protein complement(916788..917513) Escherichia coli APEC O1 4491403 YP_851995.1 CDS ycaD NC_008563.1 917728 918876 D MFS family transporter protein 917728..918876 Escherichia coli APEC O1 4491404 YP_851996.1 CDS pflA NC_008563.1 918973 919770 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(918973..919770) Escherichia coli APEC O1 4491405 YP_851997.1 CDS APECO1_1189 NC_008563.1 919802 920797 R integrase complement(919802..920797) Escherichia coli APEC O1 4491406 YP_851998.1 CDS c NC_008563.1 920891 921202 R Phage protein C complement(920891..921202) Escherichia coli APEC O1 4491407 YP_851999.1 CDS cox NC_008563.1 921307 921663 D phage-associated; Cox protein 921307..921663 Escherichia coli APEC O1 4491408 YP_852000.1 CDS gpB NC_008563.1 921835 922341 D phage-associated; hypothetical protein 921835..922341 Escherichia coli APEC O1 4491409 YP_852001.1 CDS APECO1_4462 NC_008563.1 922629 922928 D phage-associated; hypothetical protein 922629..922928 Escherichia coli APEC O1 4491410 YP_852002.1 CDS APECO1_4463 NC_008563.1 923152 923427 D phage-associated; relication initiation protein 923152..923427 Escherichia coli APEC O1 4491411 YP_852003.1 CDS APECO1_4464 NC_008563.1 923417 925708 D phage replication initiation protein 923417..925708 Escherichia coli APEC O1 4491412 YP_852004.1 CDS APECO1_4465 NC_008563.1 925932 928148 R hypothetical protein complement(925932..928148) Escherichia coli APEC O1 4491413 YP_852005.1 CDS APECO1_4466 NC_008563.1 928652 929686 R phage capsid protein complement(928652..929686) Escherichia coli APEC O1 4491414 YP_852006.1 CDS APECO1_4467 NC_008563.1 929686 931458 R phage terminase complement(929686..931458) Escherichia coli APEC O1 4491415 YP_852007.1 CDS APECO1_4468 NC_008563.1 931566 932486 D phage capsid scaffolding protein 931566..932486 Escherichia coli APEC O1 4491416 YP_852008.1 CDS APECO1_4469 NC_008563.1 932545 933618 D phage-associated; major capsid protein 932545..933618 Escherichia coli APEC O1 4491417 YP_852009.1 CDS APECO1_4470 NC_008563.1 933622 934365 D small terminase subunit 933622..934365 Escherichia coli APEC O1 4491418 YP_852010.1 CDS APECO1_4471 NC_008563.1 934405 934974 D capsid completion protein 934405..934974 Escherichia coli APEC O1 4491419 YP_852011.1 CDS APECO1_4472 NC_008563.1 935181 935462 D phage lysis holin 935181..935462 Escherichia coli APEC O1 4492816 YP_852012.1 CDS APECO1_4473 NC_008563.1 935462 935959 D phage lysin 935462..935959 Escherichia coli APEC O1 4492817 YP_852013.1 CDS APECO1_4474 NC_008563.1 935974 936399 D phage-associated; LysA protein 935974..936399 Escherichia coli APEC O1 4492818 YP_852014.1 CDS APECO1_4475 NC_008563.1 936387 936812 D phage-associated; LysB protein 936387..936812 Escherichia coli APEC O1 4492819 YP_852015.1 CDS APECO1_4476 NC_008563.1 936920 937387 D phage-associated; tail protein 936920..937387 Escherichia coli APEC O1 4492820 YP_852016.1 CDS APECO1_4477 NC_008563.1 937380 937832 D phage-associated; tail protein 937380..937832 Escherichia coli APEC O1 4492821 YP_852017.1 CDS APECO1_4478 NC_008563.1 937899 938534 D phage baseplate protein 937899..938534 Escherichia coli APEC O1 4492822 YP_852018.1 CDS APECO1_4479 NC_008563.1 938531 938878 D phage baseplate protein 938531..938878 Escherichia coli APEC O1 4492823 YP_852019.1 CDS APECO1_4480 NC_008563.1 938883 939791 D phage-associated; baseplate assembly protein 938883..939791 Escherichia coli APEC O1 4492824 YP_852020.1 CDS APECO1_4481 NC_008563.1 939784 940314 D tail protein 939784..940314 Escherichia coli APEC O1 4492825 YP_852021.1 CDS APECO1_4482 NC_008563.1 940325 942334 D phage-associated; tail fiber protein 940325..942334 Escherichia coli APEC O1 4492826 YP_852022.1 CDS APECO1_44822 NC_008563.1 942338 942865 D phage-associated; tail fiber assembly protein 942338..942865 Escherichia coli APEC O1 4492827 YP_852023.1 CDS funZ NC_008563.1 943266 944852 R phage-associated protein complement(943266..944852) Escherichia coli APEC O1 4492828 YP_852024.1 CDS gpF1 NC_008563.1 945243 945659 D Phage tail sheath protein; hypothetical protein 945243..945659 Escherichia coli APEC O1 4492830 YP_852025.1 CDS tnpA NC_008563.1 945800 946996 D transposase for ISEc12; hypothetical protein 945800..946996 Escherichia coli APEC O1 4492831 YP_852026.1 CDS tnpA NC_008563.1 947354 948103 D ISEc12 ATP-binding protein; hypothetical protein 947354..948103 Escherichia coli APEC O1 4492832 YP_852027.1 CDS gpF1 NC_008563.1 948154 949020 D Phage tail sheath protein; hypothetical protein 948154..949020 Escherichia coli APEC O1 4492833 YP_852028.1 CDS gpFII NC_008563.1 949033 949551 D Phage tail tube protein FII; hypothetical protein 949033..949551 Escherichia coli APEC O1 4492834 YP_852029.1 CDS APECO1_10 NC_008563.1 949563 949952 R hypothetical protein complement(949563..949952) Escherichia coli APEC O1 4492835 YP_852030.1 CDS gpT NC_008563.1 950028 952475 D Phage-related tail protein; hypothetical protein 950028..952475 Escherichia coli APEC O1 4494330 YP_852031.1 CDS gpU NC_008563.1 952490 952969 D essential tail protein; gpU phage protein 952490..952969 Escherichia coli APEC O1 4494331 YP_852032.1 CDS gpD NC_008563.1 952969 954132 D essential tail protein; hypothetical protein 952969..954132 Escherichia coli APEC O1 4494332 YP_852033.1 CDS ogr NC_008563.1 954178 954432 D Phage transcriptional activator; in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 954178..954432 Escherichia coli APEC O1 4494333 YP_852034.1 CDS pflB NC_008563.1 954751 957033 R pyruvate formate lyase I; protein PflB complement(954751..957033) Escherichia coli APEC O1 4494334 YP_852035.1 CDS focA NC_008563.1 957088 958284 R Degradation of small molecules: carbon compounds; formate transporter complement(957088..958284) Escherichia coli APEC O1 4494335 YP_852036.1 CDS ycaO NC_008563.1 958351 960120 R hypothetical protein complement(958351..960120) Escherichia coli APEC O1 4494336 YP_852037.1 CDS ycaP NC_008563.1 960241 960933 D hypothetical protein 960241..960933 Escherichia coli APEC O1 4494337 YP_852038.1 CDS serC NC_008563.1 961132 962220 D 3-phosphoserine/phosphohydroxythreonine aminotransferase; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 961132..962220 Escherichia coli APEC O1 4494338 YP_852039.1 CDS aroA NC_008563.1 962291 963574 D 5-enolpyruvylshikimate-3-phosphate synthetase; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 962291..963574 Escherichia coli APEC O1 4494339 YP_852040.1 CDS ycaL NC_008563.1 963735 964508 D predicted peptidase with chaperone function; hypothetical protein 963735..964508 Escherichia coli APEC O1 4494340 YP_852041.1 CDS cmk NC_008563.1 964681 965364 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 964681..965364 Escherichia coli APEC O1 4494341 YP_852042.1 CDS rpsA NC_008563.1 965475 967148 D 30S ribosomal subunit protein S1; in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 965475..967148 Escherichia coli APEC O1 4494342 YP_852043.1 CDS APECO1_24 NC_008563.1 967317 967625 R hypothetical protein complement(967317..967625) Escherichia coli APEC O1 4494343 YP_852044.1 CDS ycaI NC_008563.1 967798 969663 D conserved inner membrane protein; hypothetical protein 967798..969663 Escherichia coli APEC O1 4494344 YP_852045.1 CDS msbA NC_008563.1 970093 971841 D probable transport ATP-binding protein MsbA; involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 970093..971841 Escherichia coli APEC O1 4494345 YP_852046.1 CDS lpxK NC_008563.1 971838 972824 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 971838..972824 Escherichia coli APEC O1 4494346 YP_852047.1 CDS ycaQ NC_008563.1 972861 974093 D hypothetical protein 972861..974093 Escherichia coli APEC O1 4494347 YP_852048.1 CDS APECO1_29 NC_008563.1 974150 974419 R hypothetical protein complement(974150..974419) Escherichia coli APEC O1 4494348 YP_852049.1 CDS kdsB NC_008563.1 974324 975070 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 974324..975070 Escherichia coli APEC O1 4491498 YP_852050.1 CDS ycbJ NC_008563.1 975224 976117 D hypothetical protein 975224..976117 Escherichia coli APEC O1 4491499 YP_852051.1 CDS ycbC NC_008563.1 976094 976873 R hypothetical protein complement(976094..976873) Escherichia coli APEC O1 4491500 YP_852052.1 CDS smtA NC_008563.1 976997 977794 D predicted S-adenosyl-L-methionine-dependent methyltransferase; involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 976997..977794 Escherichia coli APEC O1 4491501 YP_852053.1 CDS mukF NC_008563.1 977791 979113 D Ca2+-binding protein involved in chromosome partitioning; acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 977791..979113 Escherichia coli APEC O1 4491502 YP_852054.1 CDS mukE NC_008563.1 979067 979798 D protein involved in chromosome partitioning; acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 979067..979798 Escherichia coli APEC O1 4491503 YP_852055.1 CDS mukB NC_008563.1 979798 984258 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 979798..984258 Escherichia coli APEC O1 4491504 YP_852056.1 CDS ycbB NC_008563.1 984519 986366 D predicted carboxypeptidase; hypothetical protein 984519..986366 Escherichia coli APEC O1 4491505 YP_852057.1 CDS ycbK NC_008563.1 986547 987095 D hypothetical protein 986547..987095 Escherichia coli APEC O1 4491506 YP_852058.1 CDS ycbL NC_008563.1 987122 987769 D hypothetical protein 987122..987769 Escherichia coli APEC O1 4491507 YP_852059.1 CDS aspC NC_008563.1 987819 989009 R aspartate aminotransferase, PLP-dependent; catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(987819..989009) Escherichia coli APEC O1 4491508 YP_852060.1 CDS ompF NC_008563.1 989194 990282 R outer membrane porin 1a (Ia;b;F); outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(989194..990282) Escherichia coli APEC O1 4491509 YP_852061.2 CDS asnC NC_008563.1 990884 992284 R asparagine tRNA synthetase; catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(990884..992284) Escherichia coli APEC O1 4491510 YP_852062.1 CDS pncB NC_008563.1 992453 993703 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(992453..993703) Escherichia coli APEC O1 4491511 YP_852063.1 CDS pepN NC_008563.1 993921 996533 D aminopeptidase N 993921..996533 Escherichia coli APEC O1 4491512 YP_852064.1 CDS ssuB NC_008563.1 996728 997495 R alkanesulfonate transporter subunit; part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(996728..997495) Escherichia coli APEC O1 4491513 YP_852065.1 CDS ssuC NC_008563.1 997492 998286 R alkanesulfonate transporter subunit; part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease complement(997492..998286) Escherichia coli APEC O1 4491514 YP_852066.1 CDS ssuD NC_008563.1 998295 999440 R alkanesulfonate monooxygenase, FMNH(2)-dependent; catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(998295..999440) Escherichia coli APEC O1 4491515 YP_852067.1 CDS ssuA NC_008563.1 999437 1000438 R alkanesulfonate transporter subunit; part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(999437..1000438) Escherichia coli APEC O1 4491516 YP_852068.1 CDS ssuE NC_008563.1 1000389 1000964 R NAD(P)H-dependent FMN reductase complement(1000389..1000964) Escherichia coli APEC O1 4491517 YP_852069.1 CDS pyrD NC_008563.1 1001201 1002211 D dihydro-orotate oxidase, FMN-linked; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1001201..1002211 Escherichia coli APEC O1 4493773 YP_852070.1 CDS ycbW NC_008563.1 1002349 1002927 D hypothetical protein 1002349..1002927 Escherichia coli APEC O1 4493774 YP_852071.1 CDS ycbX NC_008563.1 1002924 1004033 R predicted 2Fe-2S cluster-containing protein; hypothetical protein complement(1002924..1004033) Escherichia coli APEC O1 4493775 YP_852072.1 CDS rlmL NC_008563.1 1004131 1006239 D predicted methyltransferase; catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1004131..1006239 Escherichia coli APEC O1 4493776 YP_852073.1 CDS uup NC_008563.1 1006251 1008158 D ABC transporter ATP-binding protein uup; Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1006251..1008158 Escherichia coli APEC O1 4493777 YP_852074.1 CDS pqiA NC_008563.1 1008288 1009541 D paraquat-inducible protein A 1008288..1009541 Escherichia coli APEC O1 4493778 YP_852075.1 CDS pqiB NC_008563.1 1009528 1011186 D paraquat-inducible protein B 1009528..1011186 Escherichia coli APEC O1 4493779 YP_852076.1 CDS APECO1_58 NC_008563.1 1011183 1011746 D hypothetical protein 1011183..1011746 Escherichia coli APEC O1 4493780 YP_852077.1 CDS fabA NC_008563.1 1012239 1012955 R 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1012239..1012955) Escherichia coli APEC O1 4493781 YP_852078.1 CDS ycbZ NC_008563.1 1012826 1014412 R predicted peptidase; hypothetical protein complement(1012826..1014412) Escherichia coli APEC O1 4493782 YP_852079.1 CDS ycbG NC_008563.1 1014772 1015224 D hypothetical protein 1014772..1015224 Escherichia coli APEC O1 4493783 YP_852080.1 CDS ompA NC_008563.1 1015302 1016414 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1015302..1016414) Escherichia coli APEC O1 4493784 YP_852081.1 CDS sulA NC_008563.1 1016698 1017207 R SOS cell division inhibitor; suppressor of lon; inhibits cell division and ftsZ ring formation; SOS cell division inhibitor complement(1016698..1017207) Escherichia coli APEC O1 4493785 YP_852082.1 CDS yccR NC_008563.1 1017426 1018055 D hypothetical protein 1017426..1018055 Escherichia coli APEC O1 4493786 YP_852083.1 CDS yccS NC_008563.1 1018018 1020180 R predicted inner membrane protein of unknown function; hypothetical protein complement(1018018..1020180) Escherichia coli APEC O1 4493787 YP_852084.1 CDS yccF NC_008563.1 1020190 1020636 R hypothetical protein complement(1020190..1020636) Escherichia coli APEC O1 4493788 YP_852085.1 CDS helD NC_008563.1 1020666 1022813 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1020666..1022813 Escherichia coli APEC O1 4493789 YP_852086.1 CDS mgsA NC_008563.1 1022845 1023312 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1022845..1023312) Escherichia coli APEC O1 4493790 YP_852087.1 CDS APECO1_69 NC_008563.1 1023399 1024061 R hypothetical protein complement(1023399..1024061) Escherichia coli APEC O1 4493791 YP_852088.1 CDS APECO1_70 NC_008563.1 1024180 1024647 D hypothetical protein 1024180..1024647 Escherichia coli APEC O1 4494643 YP_852089.1 CDS APECO1_71 NC_008563.1 1024692 1025060 R heat shock protein HspQ complement(1024692..1025060) Escherichia coli APEC O1 4494644 YP_852090.1 CDS yccW NC_008563.1 1025067 1026257 R hypothetical protein complement(1025067..1026257) Escherichia coli APEC O1 4494645 YP_852091.1 CDS yccX NC_008563.1 1026139 1026630 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1026139..1026630 Escherichia coli APEC O1 4494646 YP_852092.1 CDS yccK NC_008563.1 1026627 1026956 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1026627..1026956) Escherichia coli APEC O1 4494647 YP_852093.1 CDS yccA NC_008563.1 1027048 1027707 R hypothetical protein complement(1027048..1027707) Escherichia coli APEC O1 4494648 YP_852094.1 CDS hyaA NC_008563.1 1028401 1029546 D hydrogenase 1, small subunit 1028401..1029546 Escherichia coli APEC O1 4494649 YP_852095.1 CDS hyaB NC_008563.1 1029543 1031336 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1029543..1031336 Escherichia coli APEC O1 4494650 YP_852096.1 CDS hyaC NC_008563.1 1031355 1032062 D enzyme; Energy metabolism, carbon: Aerobic respiration; hydrogenase 1 b-type cytochrome subunit 1031355..1032062 Escherichia coli APEC O1 4494651 YP_852097.1 CDS hyaD NC_008563.1 1032059 1032646 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1032059..1032646 Escherichia coli APEC O1 4494652 YP_852098.1 CDS hyaE NC_008563.1 1032643 1033041 D involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1032643..1033041 Escherichia coli APEC O1 4494653 YP_852099.1 CDS hyaF NC_008563.1 1032978 1033895 D hydrogenase-1 operon protein HyaF 1032978..1033895 Escherichia coli APEC O1 4494654 YP_852100.1 CDS appC NC_008563.1 1034023 1035573 D cytochrome bd-II oxidase subunit I 1034023..1035573 Escherichia coli APEC O1 4494655 YP_852101.1 CDS appB NC_008563.1 1035585 1036721 D cytochrome bd-II oxidase subunit II 1035585..1036721 Escherichia coli APEC O1 4494656 YP_852102.1 CDS appA NC_008563.1 1036876 1038216 D phosphoanhydride phosphorylase 1036876..1038216 Escherichia coli APEC O1 4494657 YP_852103.1 CDS yccM NC_008563.1 1039530 1040603 R ferredoxin; electron transport protein YccM complement(1039530..1040603) Escherichia coli APEC O1 4494468 YP_852104.1 CDS torS NC_008563.1 1040686 1043418 R Histidine kinase; Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1040686..1043418) Escherichia coli APEC O1 4494469 YP_852105.1 CDS torT NC_008563.1 1043501 1044529 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1043501..1044529 Escherichia coli APEC O1 4494470 YP_852106.1 CDS torR NC_008563.1 1044502 1045194 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1044502..1045194) Escherichia coli APEC O1 4494471 YP_852107.1 CDS torC NC_008563.1 1045324 1046496 D cytochrome c-type protein TorC 1045324..1046496 Escherichia coli APEC O1 4494472 YP_852108.1 CDS torA NC_008563.1 1046496 1049042 D trimethylamine-N-oxide reductase 1 1046496..1049042 Escherichia coli APEC O1 4494473 YP_852109.1 CDS torD NC_008563.1 1049006 1049638 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1049006..1049638 Escherichia coli APEC O1 4494474 YP_852110.1 CDS yccD NC_008563.1 1049994 1050299 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1049994..1050299) Escherichia coli APEC O1 4494475 YP_852111.1 CDS cbpA NC_008563.1 1050299 1051219 R DnaJ homolog that functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1050299..1051219) Escherichia coli APEC O1 4494476 YP_852112.1 CDS agp NC_008563.1 1051754 1052995 D glucose-1-phosphatase/inositol phosphatase 1051754..1052995 Escherichia coli APEC O1 4494477 YP_852113.1 CDS wrbA NC_008563.1 1053281 1053877 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(1053281..1053877) Escherichia coli APEC O1 4494478 YP_852114.1 CDS ycdG NC_008563.1 1054506 1055201 R transporter complement(1054506..1055201) Escherichia coli APEC O1 4494479 YP_852115.1 CDS APECO1_97 NC_008563.1 1055198 1055794 R hypothetical protein complement(1055198..1055794) Escherichia coli APEC O1 4494480 YP_852116.1 CDS ycdH NC_008563.1 1055749 1056324 R oxidoreductase, flavin:NADH component complement(1055749..1056324) Escherichia coli APEC O1 4494481 YP_852117.1 CDS ycdI NC_008563.1 1056254 1056844 R hypothetical protein complement(1056254..1056844) Escherichia coli APEC O1 4494482 YP_852118.1 CDS rarA NC_008563.1 1056854 1057654 R hydrolase complement(1056854..1057654) Escherichia coli APEC O1 4494483 YP_852119.1 CDS ycdK NC_008563.1 1057662 1058048 R hypothetical protein complement(1057662..1058048) Escherichia coli APEC O1 4494484 YP_852120.1 CDS APECO1_102 NC_008563.1 1058060 1058794 R hypothetical protein complement(1058060..1058794) Escherichia coli APEC O1 4494485 YP_852121.1 CDS ycdM NC_008563.1 1058752 1059900 R monooxygenase YcdM complement(1058752..1059900) Escherichia coli APEC O1 4494486 YP_852122.1 CDS ycdC NC_008563.1 1060130 1060768 D transcriptional regulator YcdC 1060130..1060768 Escherichia coli APEC O1 4495210 YP_852123.1 CDS putA NC_008563.1 1060808 1064770 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1060808..1064770) Escherichia coli APEC O1 4495211 YP_852124.1 CDS putP NC_008563.1 1065193 1066701 D proline:sodium symporter 1065193..1066701 Escherichia coli APEC O1 4495212 YP_852125.1 CDS ycdN NC_008563.1 1066912 1067751 D hypothetical protein 1066912..1067751 Escherichia coli APEC O1 4495213 YP_852126.1 CDS ycdO NC_008563.1 1067809 1068936 D hypothetical protein 1067809..1068936 Escherichia coli APEC O1 4495214 YP_852127.1 CDS ycdB NC_008563.1 1068942 1070213 D hypothetical protein 1068942..1070213 Escherichia coli APEC O1 4495215 YP_852128.1 CDS phoH NC_008563.1 1070704 1071627 D hypothetical protein 1070704..1071627 Escherichia coli APEC O1 4495217 YP_852129.1 CDS pgaD NC_008563.1 1071677 1072090 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein complement(1071677..1072090) Escherichia coli APEC O1 4495218 YP_852130.1 CDS ycdQ NC_008563.1 1072092 1073417 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1072092..1073417) Escherichia coli APEC O1 4495219 YP_852131.1 CDS pgaB NC_008563.1 1073410 1075428 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1073410..1075428) Escherichia coli APEC O1 4495220 YP_852132.1 CDS pgaA NC_008563.1 1075437 1077860 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1075437..1077860) Escherichia coli APEC O1 4495221 YP_852133.1 CDS ycdT NC_008563.1 1078448 1079815 D diguanylate cyclase 1078448..1079815 Escherichia coli APEC O1 4495222 YP_852135.1 CDS ycdW NC_008563.1 1080202 1081179 D dehydrogenase 1080202..1081179 Escherichia coli APEC O1 4495224 YP_852136.1 CDS ycdX NC_008563.1 1081234 1081971 D hydrolase 1081234..1081971 Escherichia coli APEC O1 4495225 YP_852137.1 CDS ycdY NC_008563.1 1081995 1082549 D hypothetical protein 1081995..1082549 Escherichia coli APEC O1 4495226 YP_852138.1 CDS ycdZ NC_008563.1 1082603 1083142 D hypothetical protein 1082603..1083142 Escherichia coli APEC O1 4495227 YP_852139.1 CDS csgG NC_008563.1 1083207 1084040 R assembly /transport component in curli production complement(1083207..1084040) Escherichia coli APEC O1 4495228 YP_852140.1 CDS csgF NC_008563.1 1084067 1084483 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1084067..1084483) Escherichia coli APEC O1 4495229 YP_852141.1 CDS csgE NC_008563.1 1084508 1084897 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1084508..1084897) Escherichia coli APEC O1 4495846 YP_852142.1 CDS csgD NC_008563.1 1084902 1085552 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1084902..1085552) Escherichia coli APEC O1 4495847 YP_852143.1 CDS csgB NC_008563.1 1086278 1086760 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1086278..1086760 Escherichia coli APEC O1 4495848 YP_852144.1 CDS csgA NC_008563.1 1086801 1087256 D cryptic curlin major subunit 1086801..1087256 Escherichia coli APEC O1 4495849 YP_852145.2 CDS csgC NC_008563.1 1087315 1087647 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1087315..1087647 Escherichia coli APEC O1 4495850 YP_852146.1 CDS ymdA NC_008563.1 1087768 1088079 D hypothetical protein 1087768..1088079 Escherichia coli APEC O1 4495851 YP_852147.1 CDS ymdB NC_008563.1 1088174 1088707 D hypothetical protein 1088174..1088707 Escherichia coli APEC O1 4495852 YP_852148.1 CDS ymdC NC_008563.1 1088649 1090130 D synthase 1088649..1090130 Escherichia coli APEC O1 4495853 YP_852149.1 CDS mdoC NC_008563.1 1090138 1091295 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1090138..1091295) Escherichia coli APEC O1 4495854 YP_852150.1 CDS mdoG NC_008563.1 1091671 1093224 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1091671..1093224 Escherichia coli APEC O1 4495855 YP_852151.1 CDS modH NC_008563.1 1093187 1095760 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1093187..1095760 Escherichia coli APEC O1 4495856 YP_852152.1 CDS msyB NC_008563.1 1096160 1096537 R Acidic protein msyB; hypothetical protein complement(1096160..1096537) Escherichia coli APEC O1 4495857 YP_852153.1 CDS yceE NC_008563.1 1096617 1097843 R YceE/MdtG drug MFS transporter; Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1096617..1097843) Escherichia coli APEC O1 4495858 YP_852154.1 CDS htrB NC_008563.1 1098015 1098935 R Lipid A biosynthesis lauroyl acyltransferase; Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1098015..1098935) Escherichia coli APEC O1 4495859 YP_852155.1 CDS yceA NC_008563.1 1099160 1100212 D hypothetical protein 1099160..1100212 Escherichia coli APEC O1 4495860 YP_852156.1 CDS yceI NC_008563.1 1100254 1100829 R hypothetical protein complement(1100254..1100829) Escherichia coli APEC O1 4495861 YP_852157.1 CDS yceJ NC_008563.1 1100833 1101399 R cytochrome b561-like protein 2; hypothetical protein complement(1100833..1101399) Escherichia coli APEC O1 4495862 YP_852158.1 CDS solA NC_008563.1 1101821 1102939 R N-methyl-L-tryptophan oxidase; catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1101821..1102939) Escherichia coli APEC O1 4495863 YP_852159.1 CDS bssS NC_008563.1 1103054 1103311 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1103054..1103311) Escherichia coli APEC O1 4495864 YP_852160.2 CDS dinI NC_008563.1 1103598 1103843 R DNA-damage-inducible protein I; DNA damage-inducible protein I complement(1103598..1103843) Escherichia coli APEC O1 4494101 YP_852161.1 CDS pyrC NC_008563.1 1103917 1104963 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1103917..1104963) Escherichia coli APEC O1 4494102 YP_852162.1 CDS yceB NC_008563.1 1105069 1105686 R hypothetical protein complement(1105069..1105686) Escherichia coli APEC O1 4494103 YP_852163.1 CDS grxB NC_008563.1 1105763 1106410 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1105763..1106410) Escherichia coli APEC O1 4494104 YP_852164.1 CDS yceL NC_008563.1 1106474 1107712 R transport protein; Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1106474..1107712) Escherichia coli APEC O1 4494105 YP_852165.1 CDS rimJ NC_008563.1 1107918 1108502 D Ribosomal-protein-alanine acetyltransferase; ribosomal-protein-S5-alanine N-acetyltransferase 1107918..1108502 Escherichia coli APEC O1 4494106 YP_852166.1 CDS yceH NC_008563.1 1108513 1109160 D hypothetical protein 1108513..1109160 Escherichia coli APEC O1 4494107 YP_852167.1 CDS mviM NC_008563.1 1109162 1110085 D predicted oxidoreductase, NAD(P)-binding Rossmann-fold domain; hypothetical protein 1109162..1110085 Escherichia coli APEC O1 4494108 YP_852168.1 CDS mviN NC_008563.1 1110195 1111730 D inner membrane protein; hypothetical protein 1110195..1111730 Escherichia coli APEC O1 4494109 YP_852169.1 CDS flgN NC_008563.1 1111770 1112186 R flagellar biosynthesis/type III secretory pathway chaperone; flagella synthesis protein FlgN complement(1111770..1112186) Escherichia coli APEC O1 4494110 YP_852170.1 CDS flgM NC_008563.1 1112191 1112484 R Negative regulator of flagellin synthesis; regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1112191..1112484) Escherichia coli APEC O1 4494111 YP_852171.1 CDS flgA NC_008563.1 1112560 1113219 R flagellar biosynthesis; assembly of basal-body periplasmic P ring; required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1112560..1113219) Escherichia coli APEC O1 4494112 YP_852172.1 CDS flgB NC_008563.1 1113374 1113790 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1113374..1113790 Escherichia coli APEC O1 4494113 YP_852173.1 CDS flgC NC_008563.1 1113794 1114198 D FlgC; with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1113794..1114198 Escherichia coli APEC O1 4494114 YP_852174.1 CDS flgD NC_008563.1 1114210 1114905 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1114210..1114905 Escherichia coli APEC O1 4494115 YP_852175.1 CDS flgE NC_008563.1 1114930 1116135 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1114930..1116135 Escherichia coli APEC O1 4494116 YP_852176.1 CDS flgF NC_008563.1 1116155 1116910 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1116155..1116910 Escherichia coli APEC O1 4494117 YP_852177.1 CDS flgG NC_008563.1 1117082 1117864 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1117082..1117864 Escherichia coli APEC O1 4494118 YP_852178.1 CDS flgH NC_008563.1 1117908 1118615 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1117908..1118615 Escherichia coli APEC O1 4494119 YP_852179.1 CDS flgI NC_008563.1 1118624 1119724 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1118624..1119724 Escherichia coli APEC O1 4494120 YP_852180.2 CDS flgJ NC_008563.1 1119724 1120665 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1119724..1120665 Escherichia coli APEC O1 4495633 YP_852181.1 CDS flgK NC_008563.1 1120731 1122374 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1120731..1122374 Escherichia coli APEC O1 4495634 YP_852182.1 CDS flgL NC_008563.1 1122386 1123339 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1122386..1123339 Escherichia coli APEC O1 4495635 YP_852183.1 CDS rne NC_008563.1 1123534 1126719 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1123534..1126719) Escherichia coli APEC O1 4495636 YP_852184.1 CDS APECO1_167 NC_008563.1 1126800 1127174 D hypothetical protein 1126800..1127174 Escherichia coli APEC O1 4495637 YP_852185.1 CDS APECO1_168 NC_008563.1 1127292 1128251 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1127292..1128251 Escherichia coli APEC O1 4495638 YP_852186.1 CDS yceF NC_008563.1 1128363 1128986 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1128363..1128986) Escherichia coli APEC O1 4495639 YP_852187.1 CDS yceD NC_008563.1 1129146 1129667 D hypothetical protein 1129146..1129667 Escherichia coli APEC O1 4495640 YP_852188.1 CDS pslX NC_008563.1 1130003 1131043 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1130003..1131043 Escherichia coli APEC O1 4495641 YP_852189.1 CDS fabH NC_008563.1 1131111 1132064 D FabH; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1131111..1132064 Escherichia coli APEC O1 4495642 YP_852190.1 CDS fabD NC_008563.1 1132080 1133009 D FabD; malonyl-CoA-[acyl-carrier-protein] transacylase 1132080..1133009 Escherichia coli APEC O1 4495643 YP_852191.1 CDS fabG NC_008563.1 1133022 1133756 D FabG; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1133022..1133756 Escherichia coli APEC O1 4495644 YP_852192.1 CDS APECO1_175 NC_008563.1 1133913 1134194 R hypothetical protein complement(1133913..1134194) Escherichia coli APEC O1 4495645 YP_852193.1 CDS fabF NC_008563.1 1134290 1135531 D FabF; FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1134290..1135531 Escherichia coli APEC O1 4495646 YP_852194.1 CDS pabC NC_008563.1 1135651 1136460 D PabC; catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1135651..1136460 Escherichia coli APEC O1 4495647 YP_852195.1 CDS yceG NC_008563.1 1136463 1137485 D hypothetical protein 1136463..1137485 Escherichia coli APEC O1 4495648 YP_852196.1 CDS tmk NC_008563.1 1137475 1138116 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1137475..1138116 Escherichia coli APEC O1 4495649 YP_852197.1 CDS holB NC_008563.1 1138113 1139117 D HolB; catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1138113..1139117 Escherichia coli APEC O1 4495650 YP_852198.1 CDS ycfH NC_008563.1 1139128 1139925 D metallodependent hydrolase 1139128..1139925 Escherichia coli APEC O1 4495651 YP_852199.1 CDS ptsG NC_008563.1 1140220 1141653 D PtsG; phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1140220..1141653 Escherichia coli APEC O1 4493205 YP_852200.1 CDS fhuE NC_008563.1 1141713 1143902 R FhuE; ferric-rhodotorulic acid outer membrane transporter complement(1141713..1143902) Escherichia coli APEC O1 4493206 YP_852201.1 CDS ycfF NC_008563.1 1144236 1144595 D purine nucleoside phosphoramidase 1144236..1144595 Escherichia coli APEC O1 4493207 YP_852202.1 CDS ycfL NC_008563.1 1144598 1144975 D hypothetical protein 1144598..1144975 Escherichia coli APEC O1 4493208 YP_852203.1 CDS APECO1_186 NC_008563.1 1144989 1145630 D hypothetical protein 1144989..1145630 Escherichia coli APEC O1 4493209 YP_852204.1 CDS thiK NC_008563.1 1145611 1146435 D YcfN; catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1145611..1146435 Escherichia coli APEC O1 4493210 YP_852205.1 CDS nagZ NC_008563.1 1146446 1147471 D NagZ; hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1146446..1147471 Escherichia coli APEC O1 4493211 YP_852206.1 CDS ycfP NC_008563.1 1147437 1148036 D hypothetical protein 1147437..1148036 Escherichia coli APEC O1 4493212 YP_852207.1 CDS ndh NC_008563.1 1148459 1149739 D NADH dehydrogenase 1148459..1149739 Escherichia coli APEC O1 4493213 YP_852208.1 CDS ycfJ NC_008563.1 1149966 1150505 D hypothetical protein 1149966..1150505 Escherichia coli APEC O1 4493214 YP_852209.1 CDS ycfQ NC_008563.1 1150567 1151277 R transcriptional regulator complement(1150567..1151277) Escherichia coli APEC O1 4493215 YP_852210.1 CDS ycfR NC_008563.1 1151440 1151697 D hypothetical protein 1151440..1151697 Escherichia coli APEC O1 4493216 YP_852211.1 CDS ycfS NC_008563.1 1151779 1152741 R hypothetical protein complement(1151779..1152741) Escherichia coli APEC O1 4493217 YP_852212.1 CDS mfd NC_008563.1 1152886 1156380 R Mfd; transcription-repair coupling factor complement(1152886..1156380) Escherichia coli APEC O1 4493218 YP_852213.1 CDS ycfT NC_008563.1 1156460 1157533 R hypothetical protein complement(1156460..1157533) Escherichia coli APEC O1 4493219 YP_852214.1 CDS ycfU NC_008563.1 1157690 1158994 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1157690..1158994 Escherichia coli APEC O1 4493220 YP_852215.1 CDS lolD NC_008563.1 1158849 1159688 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1158849..1159688 Escherichia coli APEC O1 4493221 YP_852216.1 CDS ycfW NC_008563.1 1159688 1160932 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1159688..1160932 Escherichia coli APEC O1 4493222 YP_852217.1 CDS ycfX NC_008563.1 1160961 1161872 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1160961..1161872 Escherichia coli APEC O1 4493223 YP_852218.1 CDS cobB NC_008563.1 1161888 1162709 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1161888..1162709 Escherichia coli APEC O1 4493224 YP_852219.1 CDS ycfZ NC_008563.1 1162847 1163737 R hypothetical protein complement(1162847..1163737) Escherichia coli APEC O1 4492291 YP_852220.1 CDS ymfA NC_008563.1 1163632 1164135 R hypothetical protein complement(1163632..1164135) Escherichia coli APEC O1 4492292 YP_852221.1 CDS potD NC_008563.1 1164151 1165197 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1164151..1165197) Escherichia coli APEC O1 4492293 YP_852222.1 CDS potC NC_008563.1 1165194 1165988 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1165194..1165988) Escherichia coli APEC O1 4492294 YP_852223.1 CDS potB NC_008563.1 1165985 1166842 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1165985..1166842) Escherichia coli APEC O1 4492295 YP_852224.1 CDS potA NC_008563.1 1166826 1167962 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1166826..1167962) Escherichia coli APEC O1 4492296 YP_852225.1 CDS pepT NC_008563.1 1168212 1169438 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1168212..1169438 Escherichia coli APEC O1 4492297 YP_852226.1 CDS ycfD NC_008563.1 1169487 1170617 R hypothetical protein complement(1169487..1170617) Escherichia coli APEC O1 4492298 YP_852227.1 CDS phoQ NC_008563.1 1170684 1172144 R sensor protein PhoQ complement(1170684..1172144) Escherichia coli APEC O1 4492299 YP_852228.1 CDS phoP NC_008563.1 1172144 1172815 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1172144..1172815) Escherichia coli APEC O1 4492300 YP_852229.1 CDS purB NC_008563.1 1172984 1174354 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1172984..1174354) Escherichia coli APEC O1 4492301 YP_852230.1 CDS ycfC NC_008563.1 1174358 1175005 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1174358..1175005) Escherichia coli APEC O1 4492302 YP_852231.1 CDS mnmA NC_008563.1 1175035 1176186 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1175035..1176186) Escherichia coli APEC O1 4492303 YP_852232.1 CDS APECO1_216 NC_008563.1 1176195 1176656 R phosphohydrolase complement(1176195..1176656) Escherichia coli APEC O1 4492304 YP_852233.1 CDS rluE NC_008563.1 1176666 1177319 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1176666..1177319) Escherichia coli APEC O1 4492305 YP_852234.1 CDS APECO1_218 NC_008563.1 1177491 1178741 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1177491..1178741 Escherichia coli APEC O1 4492306 YP_852235.1 CDS int NC_008563.1 1178855 1179997 R prophage lambda integrase complement(1178855..1179997) Escherichia coli APEC O1 4492307 YP_852236.1 CDS APECO1_220 NC_008563.1 1180553 1180984 D hypothetical protein 1180553..1180984 Escherichia coli APEC O1 4492308 YP_852237.1 CDS APECO1_221 NC_008563.1 1181863 1182543 R exonuclease encoded by prophage CP-933K complement(1181863..1182543) Escherichia coli APEC O1 4492309 YP_852238.1 CDS APECO1_222 NC_008563.1 1182540 1183325 R recombination protein Bet of prophage complement(1182540..1183325) Escherichia coli APEC O1 4491791 YP_852239.1 CDS gamW NC_008563.1 1183331 1183627 R host-nuclease inhibitor protein Gam of bacteriphage complement(1183331..1183627) Escherichia coli APEC O1 4491792 YP_852240.1 CDS kil1 NC_008563.1 1183703 1183972 R Kil protein complement(1183703..1183972) Escherichia coli APEC O1 4491793 YP_852241.1 CDS APECO1_225 NC_008563.1 1184052 1184420 R ssDNA-binding protein complement(1184052..1184420) Escherichia coli APEC O1 4491794 YP_852242.1 CDS APECO1_226 NC_008563.1 1185017 1185598 D superinfection exclusion protein B of prophage 1185017..1185598 Escherichia coli APEC O1 4491795 YP_852243.1 CDS APECO1_227 NC_008563.1 1185615 1185959 R N protein complement(1185615..1185959) Escherichia coli APEC O1 4491796 YP_852244.1 CDS APECO1_228 NC_008563.1 1186324 1187076 R hypothetical protein complement(1186324..1187076) Escherichia coli APEC O1 4491797 YP_852245.1 CDS APECO1_229 NC_008563.1 1187073 1187513 R hypothetical protein complement(1187073..1187513) Escherichia coli APEC O1 4491798 YP_852246.1 CDS APECO1_230 NC_008563.1 1187670 1188365 R CI repressor of bacteriophage complement(1187670..1188365) Escherichia coli APEC O1 4491799 YP_852247.1 CDS APECO1_231 NC_008563.1 1188371 1188655 D hypothetical protein 1188371..1188655 Escherichia coli APEC O1 4491800 YP_852248.1 CDS APECO1_232 NC_008563.1 1188797 1189093 D regulatory protein CII of bacteriophage 1188797..1189093 Escherichia coli APEC O1 4491801 YP_852249.1 CDS APECO1_233 NC_008563.1 1189126 1190025 D replication protein O of bacteriophage 1189126..1190025 Escherichia coli APEC O1 4491802 YP_852250.1 CDS APECO1_234 NC_008563.1 1190022 1190723 D replication protein P of bacteriophage 1190022..1190723 Escherichia coli APEC O1 4491803 YP_852251.1 CDS APECO1_235 NC_008563.1 1190720 1191010 D exclusion protein ren of prophage 1190720..1191010 Escherichia coli APEC O1 4491804 YP_852252.1 CDS ninB NC_008563.1 1191084 1191524 D hypothetical protein 1191084..1191524 Escherichia coli APEC O1 4491805 YP_852253.1 CDS APECO1_237 NC_008563.1 1191461 1192048 D DNA N-6-adenine-methyltransferase of bacteriophage 1191461..1192048 Escherichia coli APEC O1 4491806 YP_852254.1 CDS APECO1_238 NC_008563.1 1192182 1192565 D hypothetical protein 1192182..1192565 Escherichia coli APEC O1 4491807 YP_852255.1 CDS rusA NC_008563.1 1192772 1193134 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1192772..1193134 Escherichia coli APEC O1 4491808 YP_852256.1 CDS ybcQ NC_008563.1 1193357 1193740 D similar to lambdoid prophage; antitermination protein Q-like protein 1193357..1193740 Escherichia coli APEC O1 4491809 YP_852257.1 CDS nmpC NC_008563.1 1193929 1195071 R outer membrane porin protein NmpC complement(1193929..1195071) Escherichia coli APEC O1 4491810 YP_852258.1 CDS ybcS2 NC_008563.1 1195815 1196312 D bacteriophage lambda lysozyme-like protein 1195815..1196312 Escherichia coli APEC O1 4495652 YP_852259.1 CDS APECO1_243 NC_008563.1 1196297 1196770 D Rz endopeptidase from lambdoid prophage 1196297..1196770 Escherichia coli APEC O1 4495653 YP_852260.1 CDS bor NC_008563.1 1196802 1197110 R lambda prophage Bor protein complement(1196802..1197110) Escherichia coli APEC O1 4495654 YP_852261.1 CDS tonB NC_008563.1 1197522 1197902 D truncated TonB-like membrane protein encoded within prophage 1197522..1197902 Escherichia coli APEC O1 4495655 YP_852262.1 CDS APECO1_246 NC_008563.1 1198025 1198378 R hypothetical protein complement(1198025..1198378) Escherichia coli APEC O1 4495656 YP_852263.1 CDS nohA2 NC_008563.1 1198763 1199311 D prophage Qin DNA packaging protein NU1-like protein 1198763..1199311 Escherichia coli APEC O1 4495657 YP_852264.1 CDS APECO1_248 NC_008563.1 1199241 1201211 D DNA packaging protein of prophage; terminase large subunit 1199241..1201211 Escherichia coli APEC O1 4495658 YP_852265.1 CDS APECO1_249 NC_008563.1 1201368 1202990 D capsid protein of prophage 1201368..1202990 Escherichia coli APEC O1 4495659 YP_852266.1 CDS APECO1_250 NC_008563.1 1202980 1204485 D head-tail preconnector protein gp5 of bacteriophage 1202980..1204485 Escherichia coli APEC O1 4495660 YP_852267.1 CDS APECO1_251 NC_008563.1 1204501 1204872 R hypothetical protein complement(1204501..1204872) Escherichia coli APEC O1 4495661 YP_852268.1 CDS APECO1_252 NC_008563.1 1204927 1205955 D capsid protein of prophage 1204927..1205955 Escherichia coli APEC O1 4495662 YP_852269.1 CDS APECO1_253 NC_008563.1 1205959 1206381 D hypothetical protein 1205959..1206381 Escherichia coli APEC O1 4495663 YP_852270.1 CDS APECO1_254 NC_008563.1 1206338 1206727 D head-tail joining protein of prophage 1206338..1206727 Escherichia coli APEC O1 4495664 YP_852271.1 CDS APECO1_255 NC_008563.1 1206739 1207317 D tail fiber component Z of prophage 1206739..1207317 Escherichia coli APEC O1 4495665 YP_852272.1 CDS APECO1_256 NC_008563.1 1207314 1207709 D tail component of prophage 1207314..1207709 Escherichia coli APEC O1 4495666 YP_852273.1 CDS APECO1_257 NC_008563.1 1207687 1208457 D tail component of prophage CP-933X 1207687..1208457 Escherichia coli APEC O1 4495667 YP_852274.1 CDS APECO1_258 NC_008563.1 1208473 1208895 D tail component of prophage 1208473..1208895 Escherichia coli APEC O1 4495668 YP_852275.1 CDS APECO1_259 NC_008563.1 1208877 1209311 D tail component of prophage 1208877..1209311 Escherichia coli APEC O1 4495669 YP_852276.1 CDS APECO1_260 NC_008563.1 1209304 1211865 D tail component of prophage 1209304..1211865 Escherichia coli APEC O1 4495670 YP_852277.1 CDS APECO1_261 NC_008563.1 1211862 1212191 D minor tail protein 1211862..1212191 Escherichia coli APEC O1 4493625 YP_852278.1 CDS APECO1_262 NC_008563.1 1212191 1212889 D tail component of prophage 1212191..1212889 Escherichia coli APEC O1 4493626 YP_852279.1 CDS APECO1_263 NC_008563.1 1212895 1213638 D tail fiber component K of prophage 1212895..1213638 Escherichia coli APEC O1 4493627 YP_852280.1 CDS APECO1_265 NC_008563.1 1213536 1214207 D tail component of prophage 1213536..1214207 Escherichia coli APEC O1 4493628 YP_852281.1 CDS APECO1_266 NC_008563.1 1214268 1217018 D tail component of prophage 1214268..1217018 Escherichia coli APEC O1 4493629 YP_852282.1 CDS APECO1_267 NC_008563.1 1216993 1217751 D tail component of prophage 1216993..1217751 Escherichia coli APEC O1 4493630 YP_852283.1 CDS APECO1_268 NC_008563.1 1217804 1219870 D hypothetical protein 1217804..1219870 Escherichia coli APEC O1 4493631 YP_852284.1 CDS APECO1_269 NC_008563.1 1219867 1220145 D hypothetical protein 1219867..1220145 Escherichia coli APEC O1 4493632 YP_852285.1 CDS APECO1_270 NC_008563.1 1220158 1220451 D hypothetical protein 1220158..1220451 Escherichia coli APEC O1 4493633 YP_852286.1 CDS sitD NC_008563.1 1220543 1221400 R Mn+2/Fe+2 ABC transporter inner membrane subunit SitD complement(1220543..1221400) Escherichia coli APEC O1 4493634 YP_852287.1 CDS sitC NC_008563.1 1221397 1222254 R Mn+2/Fe+2 ABC transporter inner membrane subunit SitC complement(1221397..1222254) Escherichia coli APEC O1 4493635 YP_852288.1 CDS sitB NC_008563.1 1222251 1223078 R Mn+2/Fe+2 ABC transporter ATPase SitB complement(1222251..1223078) Escherichia coli APEC O1 4493636 YP_852289.1 CDS sitA NC_008563.1 1223078 1223992 R Mn+2/Fe+2 ABC transporter substrate-binding protein complement(1223078..1223992) Escherichia coli APEC O1 4493637 YP_852290.1 CDS APECO1_275 NC_008563.1 1224679 1225449 D hypothetical protein 1224679..1225449 Escherichia coli APEC O1 4493638 YP_852291.1 CDS ycgX NC_008563.1 1226335 1226739 R hypothetical protein complement(1226335..1226739) Escherichia coli APEC O1 4493639 YP_852292.1 CDS ycgE NC_008563.1 1226960 1227691 R transcriptional regulator complement(1226960..1227691) Escherichia coli APEC O1 4493640 YP_852293.1 CDS ycgF NC_008563.1 1227896 1229107 R hypothetical protein complement(1227896..1229107) Escherichia coli APEC O1 4493641 YP_852294.1 CDS APECO1_279 NC_008563.1 1229700 1229972 D hypothetical protein 1229700..1229972 Escherichia coli APEC O1 4493642 YP_852295.1 CDS ymgB NC_008563.1 1230001 1230267 D hypothetical protein 1230001..1230267 Escherichia coli APEC O1 4493643 YP_852296.1 CDS APECO1_281 NC_008563.1 1231100 1231819 D hypothetical protein 1231100..1231819 Escherichia coli APEC O1 4493644 YP_852297.1 CDS APECO1_282 NC_008563.1 1233036 1233413 D hypothetical protein 1233036..1233413 Escherichia coli APEC O1 4491597 YP_852298.1 CDS APECO1_283 NC_008563.1 1233559 1234086 D hypothetical protein 1233559..1234086 Escherichia coli APEC O1 4491598 YP_852299.1 CDS APECO1_284 NC_008563.1 1234144 1234479 R hypothetical protein complement(1234144..1234479) Escherichia coli APEC O1 4491599 YP_852300.1 CDS APECO1_285 NC_008563.1 1234483 1234767 R hypothetical protein complement(1234483..1234767) Escherichia coli APEC O1 4491600 YP_852301.1 CDS APECO1_286 NC_008563.1 1235420 1235746 D hypothetical protein 1235420..1235746 Escherichia coli APEC O1 4491601 YP_852302.1 CDS minE NC_008563.1 1236119 1236385 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1236119..1236385) Escherichia coli APEC O1 4491602 YP_852303.1 CDS minD NC_008563.1 1236389 1237201 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1236389..1237201) Escherichia coli APEC O1 4491603 YP_852304.1 CDS minC NC_008563.1 1237225 1237920 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1237225..1237920) Escherichia coli APEC O1 4491604 YP_852305.1 CDS ycgJ NC_008563.1 1238440 1238808 D hypothetical protein 1238440..1238808 Escherichia coli APEC O1 4491605 YP_852306.1 CDS ycgK NC_008563.1 1238928 1239329 R hypothetical protein complement(1238928..1239329) Escherichia coli APEC O1 4491606 YP_852307.1 CDS APECO1_292 NC_008563.1 1239538 1239864 D hypothetical protein 1239538..1239864 Escherichia coli APEC O1 4491607 YP_852308.1 CDS ycgM NC_008563.1 1239936 1240595 D hypothetical protein 1239936..1240595 Escherichia coli APEC O1 4491608 YP_852309.2 CDS ycgN NC_008563.1 1240687 1241133 D hypothetical protein 1240687..1241133 Escherichia coli APEC O1 4491609 YP_852310.1 CDS umuD NC_008563.1 1241927 1242346 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1241927..1242346 Escherichia coli APEC O1 4491610 YP_852311.1 CDS umuC NC_008563.1 1242346 1243614 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1242346..1243614 Escherichia coli APEC O1 4491611 YP_852312.1 CDS dsbB NC_008563.1 1243659 1244195 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1243659..1244195) Escherichia coli APEC O1 4491612 YP_852313.1 CDS nhaB NC_008563.1 1244335 1245876 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1244335..1245876) Escherichia coli APEC O1 4491613 YP_852314.1 CDS fadR NC_008563.1 1246098 1246817 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1246098..1246817 Escherichia coli APEC O1 4491614 YP_852315.1 CDS ycgB NC_008563.1 1246980 1248512 R SpoVR family protein complement(1246980..1248512) Escherichia coli APEC O1 4491615 YP_852316.1 CDS dadA NC_008563.1 1248836 1250140 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1248836..1250140 Escherichia coli APEC O1 4492425 YP_852317.1 CDS dadX NC_008563.1 1250150 1251220 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1250150..1251220 Escherichia coli APEC O1 4492426 YP_852318.1 CDS ycgO NC_008563.1 1251277 1252887 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1251277..1252887) Escherichia coli APEC O1 4492427 YP_852319.1 CDS ldcA NC_008563.1 1253108 1254022 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1253108..1254022) Escherichia coli APEC O1 4492428 YP_852320.1 CDS mltE NC_008563.1 1254008 1254733 D murein transglycosylase E 1254008..1254733 Escherichia coli APEC O1 4492429 YP_852321.1 CDS APECO1_306 NC_008563.1 1254735 1255469 R hypothetical protein complement(1254735..1255469) Escherichia coli APEC O1 4492430 YP_852322.1 CDS ymgE NC_008563.1 1255670 1255924 D transglycosylase 1255670..1255924 Escherichia coli APEC O1 4492431 YP_852323.1 CDS prrA NC_008563.1 1255974 1257944 R TonB dependent outer membrane receptor complement(1255974..1257944) Escherichia coli APEC O1 4492432 YP_852324.1 CDS modD NC_008563.1 1257970 1258824 R involved in molybdenum transport; molybdenum transport protein ModD complement(1257970..1258824) Escherichia coli APEC O1 4492433 YP_852325.1 CDS APECO1_310 NC_008563.1 1258821 1259633 R hypothetical protein complement(1258821..1259633) Escherichia coli APEC O1 4492434 YP_852326.1 CDS APECO1_311 NC_008563.1 1259643 1260539 R iron ABCtransporter ATP-binding protein complement(1259643..1260539) Escherichia coli APEC O1 4492435 YP_852327.1 CDS APECO1_312 NC_008563.1 1260398 1261378 R iron ABCtransporter permease protein complement(1260398..1261378) Escherichia coli APEC O1 4492436 YP_852328.1 CDS APECO1_313 NC_008563.1 1261378 1262442 R iron ABCtransporter periplasmic-binding protein complement(1261378..1262442) Escherichia coli APEC O1 4492437 YP_852329.1 CDS treA NC_008563.1 1262737 1264434 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1262737..1264434) Escherichia coli APEC O1 4492438 YP_852330.1 CDS ycgC NC_008563.1 1264753 1266174 R YcgC; phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM complement(1264753..1266174) Escherichia coli APEC O1 4492439 YP_852331.1 CDS dhaL NC_008563.1 1266182 1266889 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1266182..1266889) Escherichia coli APEC O1 4492440 YP_852332.1 CDS dhaK NC_008563.1 1266825 1267925 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1266825..1267925) Escherichia coli APEC O1 4492441 YP_852333.1 CDS APECO1_318 NC_008563.1 1268114 1270042 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1268114..1270042 Escherichia coli APEC O1 4492442 YP_852334.1 CDS ychF NC_008563.1 1270446 1271537 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1270446..1271537) Escherichia coli APEC O1 4492443 YP_852335.1 CDS pth NC_008563.1 1271654 1272037 R peptidyl-tRNA hydrolase complement(1271654..1272037) Escherichia coli APEC O1 4492444 YP_852336.1 CDS ychH NC_008563.1 1272516 1272794 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1272516..1272794 Escherichia coli APEC O1 4494141 YP_852337.1 CDS ychM NC_008563.1 1272849 1274501 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1272849..1274501) Escherichia coli APEC O1 4494142 YP_852338.1 CDS prsA NC_008563.1 1274653 1275666 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1274653..1275666) Escherichia coli APEC O1 4494143 YP_852339.1 CDS ipk NC_008563.1 1275751 1276602 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1275751..1276602) Escherichia coli APEC O1 4494144 YP_852340.1 CDS lolB NC_008563.1 1276602 1277291 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1276602..1277291) Escherichia coli APEC O1 4494145 YP_852341.1 CDS hemA NC_008563.1 1277439 1278695 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1277439..1278695 Escherichia coli APEC O1 4494146 YP_852342.1 CDS prfA NC_008563.1 1278737 1279819 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1278737..1279819 Escherichia coli APEC O1 4494147 YP_852343.1 CDS hemK NC_008563.1 1279819 1280652 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1279819..1280652 Escherichia coli APEC O1 4494148 YP_852344.1 CDS APECO1_330 NC_008563.1 1280649 1281041 D transcriptional regulator 1280649..1281041 Escherichia coli APEC O1 4494149 YP_852345.1 CDS APECO1_331 NC_008563.1 1281045 1281854 D transcriptional regulator 1281045..1281854 Escherichia coli APEC O1 4494150 YP_852346.1 CDS APECO1_332 NC_008563.1 1281890 1282744 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1281890..1282744 Escherichia coli APEC O1 4494151 YP_852347.1 CDS chaA NC_008563.1 1283405 1284592 R calcium/sodium:proton antiporter complement(1283405..1284592) Escherichia coli APEC O1 4494152 YP_852348.1 CDS APECO1_334 NC_008563.1 1284769 1285068 R hypothetical protein complement(1284769..1285068) Escherichia coli APEC O1 4494153 YP_852349.1 CDS chaC NC_008563.1 1285142 1285858 D cation transport protein ChaC 1285142..1285858 Escherichia coli APEC O1 4494154 YP_852350.1 CDS ychN NC_008563.1 1285902 1286255 R hypothetical protein complement(1285902..1286255) Escherichia coli APEC O1 4494155 YP_852351.1 CDS ychO NC_008563.1 1286581 1287834 D hypothetical protein 1286581..1287834 Escherichia coli APEC O1 4494156 YP_852352.1 CDS narL NC_008563.1 1287835 1288485 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1287835..1288485) Escherichia coli APEC O1 4494157 YP_852353.1 CDS narX NC_008563.1 1288478 1290274 R nitrate/nitrite sensor protein NarX complement(1288478..1290274) Escherichia coli APEC O1 4494158 YP_852354.1 CDS narK NC_008563.1 1290613 1292004 D nitrate/nitrite transporter NarK 1290613..1292004 Escherichia coli APEC O1 4494159 YP_852355.1 CDS narG NC_008563.1 1292397 1296140 D nitrate reductase 1 subunit alpha 1292397..1296140 Escherichia coli APEC O1 4495826 YP_852356.1 CDS narH NC_008563.1 1296137 1297675 D nitrate reductase 1 subunit, beta (Fe-S) 1296137..1297675 Escherichia coli APEC O1 4495827 YP_852357.1 CDS narJ NC_008563.1 1297672 1298382 D nitrate reductase 1 subunit delta 1297672..1298382 Escherichia coli APEC O1 4495828 YP_852358.1 CDS narI NC_008563.1 1298382 1299059 D respiratory nitrate reductase 1 subunit gamma 1298382..1299059 Escherichia coli APEC O1 4495829 YP_852359.1 CDS APECO1_345 NC_008563.1 1299112 1300311 R transposase complement(1299112..1300311) Escherichia coli APEC O1 4495830 YP_852360.1 CDS purU NC_008563.1 1301104 1301946 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1301104..1301946) Escherichia coli APEC O1 4495831 YP_852361.1 CDS ychJ NC_008563.1 1301996 1302454 R hypothetical protein complement(1301996..1302454) Escherichia coli APEC O1 4495832 YP_852362.1 CDS ychK NC_008563.1 1302528 1303472 D hypothetical protein 1302528..1303472 Escherichia coli APEC O1 4495833 YP_852363.1 CDS rssB NC_008563.1 1303564 1304577 D response regulator of RpoS 1303564..1304577 Escherichia coli APEC O1 4495834 YP_852364.1 CDS galU NC_008563.1 1304779 1305687 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1304779..1305687 Escherichia coli APEC O1 4495835 YP_852365.1 CDS hns NC_008563.1 1305831 1306244 R global DNA-binding transcriptional dual regulator H-NS complement(1305831..1306244) Escherichia coli APEC O1 4495836 YP_852366.1 CDS tdk NC_008563.1 1306848 1307465 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1306848..1307465 Escherichia coli APEC O1 4495837 YP_852367.1 CDS insG NC_008563.1 1307592 1308797 R transposase InsG for insertion sequence element IS4 complement(1307592..1308797) Escherichia coli APEC O1 4495838 YP_852368.1 CDS adhE NC_008563.1 1308923 1311598 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1308923..1311598) Escherichia coli APEC O1 4495839 YP_852369.1 CDS ychE NC_008563.1 1312075 1312722 D hypothetical protein 1312075..1312722 Escherichia coli APEC O1 4495840 YP_852370.1 CDS APECO1_357 NC_008563.1 1312880 1313176 R hypothetical protein complement(1312880..1313176) Escherichia coli APEC O1 4495841 YP_852371.1 CDS oppA NC_008563.1 1313388 1315091 D periplasmic oligopeptide-binding protein 1313388..1315091 Escherichia coli APEC O1 4495842 YP_852372.1 CDS oppB NC_008563.1 1315177 1316097 D oligopeptide transporter permease 1315177..1316097 Escherichia coli APEC O1 4495843 YP_852373.1 CDS oppC NC_008563.1 1316112 1317020 D oligopeptide transporter subunit 1316112..1317020 Escherichia coli APEC O1 4495844 YP_852374.1 CDS oppD NC_008563.1 1317032 1318045 D oligopeptide ABC transporter ATP-binding protein 1317032..1318045 Escherichia coli APEC O1 4495845 YP_852375.1 CDS oppF NC_008563.1 1318042 1319046 D oligopeptide transport ATP-binding protein OppF 1318042..1319046 Escherichia coli APEC O1 4495346 YP_852376.1 CDS yciU NC_008563.1 1319099 1319506 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1319099..1319506) Escherichia coli APEC O1 4495347 YP_852377.1 CDS cls NC_008563.1 1319463 1320923 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1319463..1320923) Escherichia coli APEC O1 4495348 YP_852378.1 CDS APECO1_365 NC_008563.1 1320955 1321239 D hypothetical protein 1320955..1321239 Escherichia coli APEC O1 4495349 YP_852379.1 CDS kch NC_008563.1 1321294 1322565 R voltage-gated potassium channel complement(1321294..1322565) Escherichia coli APEC O1 4495350 YP_852380.2 CDS yciI NC_008563.1 1322847 1323143 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1322847..1323143) Escherichia coli APEC O1 4495351 YP_852381.1 CDS tonB NC_008563.1 1323352 1324083 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1323352..1324083 Escherichia coli APEC O1 4495352 YP_852382.1 CDS APECO1_369 NC_008563.1 1324123 1324521 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1324123..1324521) Escherichia coli APEC O1 4495353 YP_852383.1 CDS yciB NC_008563.1 1324627 1325166 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1324627..1325166) Escherichia coli APEC O1 4495354 YP_852384.1 CDS yciC NC_008563.1 1325196 1325939 R hypothetical protein complement(1325196..1325939) Escherichia coli APEC O1 4495355 YP_852385.1 CDS ompW NC_008563.1 1326217 1326933 D receptor for colicin S4; outer membrane protein W 1326217..1326933 Escherichia coli APEC O1 4495356 YP_852386.1 CDS intO NC_008563.1 1326979 1328109 R integrase for prophage CP-933O complement(1326979..1328109) Escherichia coli APEC O1 4495357 YP_852387.1 CDS exoO NC_008563.1 1328400 1330871 R exonuclease VIII, ds DNA exonuclease encoded by prophage complement(1328400..1330871) Escherichia coli APEC O1 4495358 YP_852388.1 CDS APECO1_375 NC_008563.1 1330934 1331479 D hypothetical protein 1330934..1331479 Escherichia coli APEC O1 4495359 YP_852389.1 CDS APECO1_376 NC_008563.1 1332735 1333373 R repressor protein encoded within prophage CP-933O complement(1332735..1333373) Escherichia coli APEC O1 4495360 YP_852390.1 CDS APECO1_377 NC_008563.1 1333453 1333707 D hypothetical protein 1333453..1333707 Escherichia coli APEC O1 4495361 YP_852391.1 CDS APECO1_378 NC_008563.1 1333619 1334116 D hypothetical protein 1333619..1334116 Escherichia coli APEC O1 4495362 YP_852392.1 CDS APECO1_379 NC_008563.1 1334188 1335246 D hypothetical protein 1334188..1335246 Escherichia coli APEC O1 4495363 YP_852393.1 CDS APECO1_380 NC_008563.1 1335287 1335709 D hypothetical protein 1335287..1335709 Escherichia coli APEC O1 4495364 YP_852394.1 CDS APECO1_381 NC_008563.1 1335751 1336863 D hypothetical protein 1335751..1336863 Escherichia coli APEC O1 4495081 YP_852395.1 CDS APECO1_382 NC_008563.1 1336879 1337880 D hypothetical protein 1336879..1337880 Escherichia coli APEC O1 4495082 YP_852396.1 CDS APECO1_383 NC_008563.1 1337992 1338282 D hypothetical protein 1337992..1338282 Escherichia coli APEC O1 4495083 YP_852397.1 CDS APECO1_384 NC_008563.1 1338692 1339099 D hypothetical protein 1338692..1339099 Escherichia coli APEC O1 4495084 YP_852398.1 CDS ydfU NC_008563.1 1339101 1340147 D hypothetical protein 1339101..1340147 Escherichia coli APEC O1 4495085 YP_852399.1 CDS rusA NC_008563.1 1340160 1340534 D endodeoxyribonuclease RusA 1340160..1340534 Escherichia coli APEC O1 4495086 YP_852400.1 CDS APECO1_387 NC_008563.1 1340531 1341352 D cryptic prophage CP-933M antitermination protein Q-like protein 1340531..1341352 Escherichia coli APEC O1 4495087 YP_852401.1 CDS APECO1_388 NC_008563.1 1341925 1342974 D DNA adenine methyltransferase encoded by prophage CP-933O 1341925..1342974 Escherichia coli APEC O1 4495088 YP_852402.1 CDS APECO1_389 NC_008563.1 1344156 1344476 D lambdoid prophage DLP12 lysis protein S-like protein 1344156..1344476 Escherichia coli APEC O1 4495089 YP_852403.1 CDS ydfR NC_008563.1 1344481 1344825 D YdfR; hypothetical protein 1344481..1344825 Escherichia coli APEC O1 4495090 YP_852404.1 CDS APECO1_391 NC_008563.1 1344791 1345063 R hypothetical protein complement(1344791..1345063) Escherichia coli APEC O1 4495091 YP_852405.1 CDS APECO1_392 NC_008563.1 1345263 1345703 D phage lysozyme 1345263..1345703 Escherichia coli APEC O1 4495092 YP_852406.1 CDS APECO1_393 NC_008563.1 1345646 1345933 R hypothetical protein complement(1345646..1345933) Escherichia coli APEC O1 4495093 YP_852407.1 CDS APECO1_394 NC_008563.1 1346002 1346466 D bacteriophage lambda cell lysis protein 1346002..1346466 Escherichia coli APEC O1 4495094 YP_852408.1 CDS ydfO NC_008563.1 1346774 1347199 R YdfO; hypothetical protein complement(1346774..1347199) Escherichia coli APEC O1 4494005 YP_852409.1 CDS nohA2 NC_008563.1 1347623 1348411 D prophage Qin DNA packaging protein NU1-like protein 1347623..1348411 Escherichia coli APEC O1 4494006 YP_852410.1 CDS APECO1_397 NC_008563.1 1348341 1350311 D DNA packaging protein of prophage; terminase large subunit 1348341..1350311 Escherichia coli APEC O1 4494007 YP_852411.1 CDS APECO1_398 NC_008563.1 1350498 1352090 D capsid protein of prophage 1350498..1352090 Escherichia coli APEC O1 4494008 YP_852412.1 CDS APECO1_399 NC_008563.1 1352080 1353585 D capsid assembly protein of prophage 1352080..1353585 Escherichia coli APEC O1 4494009 YP_852413.1 CDS APECO1_400 NC_008563.1 1353601 1353972 R hypothetical protein complement(1353601..1353972) Escherichia coli APEC O1 4494010 YP_852414.1 CDS APECO1_401 NC_008563.1 1354027 1355055 D capsid protein of prophage 1354027..1355055 Escherichia coli APEC O1 4494011 YP_852415.1 CDS APECO1_402 NC_008563.1 1355059 1355490 D hypothetical protein 1355059..1355490 Escherichia coli APEC O1 4494012 YP_852416.1 CDS APECO1_403 NC_008563.1 1355483 1355836 D head-tail joining protein of prophage 1355483..1355836 Escherichia coli APEC O1 4494013 YP_852417.1 CDS APECO1_404 NC_008563.1 1355852 1356385 D minor tail protein 1355852..1356385 Escherichia coli APEC O1 4494014 YP_852418.1 CDS APECO1_405 NC_008563.1 1356382 1356777 D tail component of prophage 1356382..1356777 Escherichia coli APEC O1 4494015 YP_852419.1 CDS APECO1_406 NC_008563.1 1356878 1358212 R hypothetical protein complement(1356878..1358212) Escherichia coli APEC O1 4494016 YP_852420.1 CDS APECO1_407 NC_008563.1 1358403 1360976 D tail component of prophage CP-933O 1358403..1360976 Escherichia coli APEC O1 4494017 YP_852421.1 CDS APECO1_408 NC_008563.1 1360973 1361302 D minor tail protein 1360973..1361302 Escherichia coli APEC O1 4494020 YP_852422.1 CDS APECO1_409 NC_008563.1 1361302 1362000 D minor tail protein 1361302..1362000 Escherichia coli APEC O1 4494021 YP_852423.1 CDS APECO1_410 NC_008563.1 1362005 1362748 D tail fiber component K of prophage 1362005..1362748 Escherichia coli APEC O1 4494022 YP_852424.1 CDS APECO1_411 NC_008563.1 1362646 1363287 D tail component of prophage CP-933K 1362646..1363287 Escherichia coli APEC O1 4494023 YP_852425.1 CDS APECO1_412 NC_008563.1 1363361 1363699 D hypothetical protein 1363361..1363699 Escherichia coli APEC O1 4493165 YP_852426.1 CDS APECO1_413 NC_008563.1 1363766 1367245 D tail component of prophage 1363766..1367245 Escherichia coli APEC O1 4493166 YP_852427.1 CDS APECO1_414 NC_008563.1 1367313 1367912 D hypothetical protein 1367313..1367912 Escherichia coli APEC O1 4493168 YP_852428.1 CDS APECO1_415 NC_008563.1 1368064 1371171 D tail fiber protein 1368064..1371171 Escherichia coli APEC O1 4493169 YP_852429.1 CDS ynaC NC_008563.1 1371171 1371755 D phage-related tail fiber assembly protein G 1371171..1371755 Escherichia coli APEC O1 4493170 YP_852430.1 CDS APECO1_417 NC_008563.1 1371810 1372478 R hypothetical protein complement(1371810..1372478) Escherichia coli APEC O1 4493171 YP_852431.1 CDS APECO1_418 NC_008563.1 1372624 1372974 R hypothetical protein complement(1372624..1372974) Escherichia coli APEC O1 4493172 YP_852432.1 CDS APECO1_419 NC_008563.1 1373577 1374083 R hypothetical protein complement(1373577..1374083) Escherichia coli APEC O1 4493173 YP_852433.1 CDS yciF NC_008563.1 1374129 1374650 R hypothetical protein complement(1374129..1374650) Escherichia coli APEC O1 4493174 YP_852434.1 CDS trpA NC_008563.1 1375275 1376081 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1375275..1376081) Escherichia coli APEC O1 4493175 YP_852435.1 CDS trpB NC_008563.1 1376081 1377274 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1376081..1377274) Escherichia coli APEC O1 4493176 YP_852436.1 CDS trpC NC_008563.1 1377286 1378644 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1377286..1378644) Escherichia coli APEC O1 4493177 YP_852437.1 CDS trpD NC_008563.1 1378648 1380243 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1378648..1380243) Escherichia coli APEC O1 4493178 YP_852438.1 CDS trpE NC_008563.1 1380243 1381805 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1380243..1381805) Escherichia coli APEC O1 4493179 YP_852439.1 CDS trpH NC_008563.1 1382100 1382960 D hypothetical protein 1382100..1382960 Escherichia coli APEC O1 4493180 YP_852440.1 CDS APECO1_427 NC_008563.1 1382921 1383577 D hypothetical protein 1382921..1383577 Escherichia coli APEC O1 4493181 YP_852441.1 CDS yciQ NC_008563.1 1383602 1385500 D hypothetical protein 1383602..1385500 Escherichia coli APEC O1 4493182 YP_852442.1 CDS rluB NC_008563.1 1385713 1386588 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1385713..1386588 Escherichia coli APEC O1 4493183 YP_852443.1 CDS btuR NC_008563.1 1386628 1387218 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1386628..1387218) Escherichia coli APEC O1 4493184 YP_852444.1 CDS yciK NC_008563.1 1387215 1387973 R short chain dehydrogenase complement(1387215..1387973) Escherichia coli APEC O1 4492221 YP_852445.1 CDS sohB NC_008563.1 1388193 1389242 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1388193..1389242 Escherichia coli APEC O1 4492222 YP_852446.1 CDS APECO1_433 NC_008563.1 1389278 1389529 R hypothetical protein complement(1389278..1389529) Escherichia coli APEC O1 4492223 YP_852447.1 CDS topA NC_008563.1 1389867 1392506 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1389867..1392506 Escherichia coli APEC O1 4492224 YP_852448.1 CDS cysB NC_008563.1 1392716 1393690 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1392716..1393690 Escherichia coli APEC O1 4492225 YP_852449.1 CDS acnA NC_008563.1 1394678 1397353 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1394678..1397353 Escherichia coli APEC O1 4492226 YP_852450.1 CDS ribA NC_008563.1 1397417 1398070 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1397417..1398070) Escherichia coli APEC O1 4492227 YP_852451.1 CDS pgpB NC_008563.1 1398177 1398941 D phosphatidylglycerophosphatase B 1398177..1398941 Escherichia coli APEC O1 4492228 YP_852452.1 CDS yciS NC_008563.1 1399090 1399398 D hypothetical protein 1399090..1399398 Escherichia coli APEC O1 4492229 YP_852453.1 CDS yciM NC_008563.1 1399405 1400574 D tetratricopeptide repeat protein 1399405..1400574 Escherichia coli APEC O1 4492230 YP_852454.1 CDS pyrF NC_008563.1 1400706 1401491 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1400706..1401491 Escherichia coli APEC O1 4492231 YP_852455.1 CDS yciH NC_008563.1 1401500 1401829 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1401500..1401829 Escherichia coli APEC O1 4492232 YP_852456.1 CDS APECO1_443 NC_008563.1 1402442 1403191 R DEOR-type transcriptional regulator complement(1402442..1403191) Escherichia coli APEC O1 4492233 YP_852457.1 CDS yciR NC_008563.1 1403602 1405587 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1403602..1405587) Escherichia coli APEC O1 4492234 YP_852458.1 CDS rnb NC_008563.1 1405822 1407756 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1405822..1407756) Escherichia coli APEC O1 4492235 YP_852459.1 CDS yciW NC_008563.1 1407824 1408951 R hypothetical protein complement(1407824..1408951) Escherichia coli APEC O1 4492236 YP_852460.1 CDS fabI NC_008563.1 1409096 1409884 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(1409096..1409884) Escherichia coli APEC O1 4492237 YP_852461.1 CDS APECO1_448 NC_008563.1 1410341 1410928 D transcription regulatory protein 1410341..1410928 Escherichia coli APEC O1 4492238 YP_852462.1 CDS APECO1_449 NC_008563.1 1411044 1412198 D acriflavine resistance protein A precursor 1411044..1412198 Escherichia coli APEC O1 4492239 YP_852463.1 CDS APECO1_450 NC_008563.1 1412198 1415305 D acriflavine resistance protein B 1412198..1415305 Escherichia coli APEC O1 4492182 YP_852464.1 CDS APECO1_451 NC_008563.1 1415309 1416682 D outer membrane channel protein 1415309..1416682 Escherichia coli APEC O1 4492183 YP_852465.1 CDS APECO1_452 NC_008563.1 1416691 1417854 D membrane transport protein 1416691..1417854 Escherichia coli APEC O1 4492184 YP_852466.1 CDS sapF NC_008563.1 1417902 1418708 R peptide ABC transporter ATP-binding protein complement(1417902..1418708) Escherichia coli APEC O1 4492185 YP_852467.1 CDS sapD NC_008563.1 1418710 1419702 R SapD; peptide ABC transporter ATP-binding protein complement(1418710..1419702) Escherichia coli APEC O1 4492186 YP_852468.1 CDS sapC NC_008563.1 1419702 1420592 R SapC; peptide ABC transporter permease complement(1419702..1420592) Escherichia coli APEC O1 4492187 YP_852469.1 CDS sapB NC_008563.1 1420579 1421544 R peptide transport system permease SapB complement(1420579..1421544) Escherichia coli APEC O1 4492188 YP_852470.1 CDS sapA NC_008563.1 1421541 1423184 R peptide transport periplasmic protein SapA complement(1421541..1423184) Escherichia coli APEC O1 4492189 YP_852471.1 CDS pspF NC_008563.1 1424169 1425161 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1424169..1425161) Escherichia coli APEC O1 4492190 YP_852472.1 CDS pspA NC_008563.1 1425312 1425980 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1425312..1425980 Escherichia coli APEC O1 4492191 YP_852473.1 CDS pspC NC_008563.1 1426258 1426617 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1426258..1426617 Escherichia coli APEC O1 4492192 YP_852474.1 CDS pspE NC_008563.1 1426922 1427236 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1426922..1427236 Escherichia coli APEC O1 4492193 YP_852475.1 CDS ycjM NC_008563.1 1427419 1429125 D sucrose phosphorylase 1427419..1429125 Escherichia coli APEC O1 4492194 YP_852476.1 CDS ycjN NC_008563.1 1429139 1430431 D ABC transporter substrate-binding protein 1429139..1430431 Escherichia coli APEC O1 4492195 YP_852477.1 CDS ycjO NC_008563.1 1430452 1431333 D binding-protein dependent transport protein 1430452..1431333 Escherichia coli APEC O1 4492196 YP_852478.1 CDS ycjP NC_008563.1 1431320 1432162 D ABC transporter permease 1431320..1432162 Escherichia coli APEC O1 4492197 YP_852479.1 CDS ycjQ NC_008563.1 1432193 1432915 D zinc-type alcohol dehydrogenase-like protein YcjQ 1432193..1432915 Escherichia coli APEC O1 4492198 YP_852480.1 CDS ycjR NC_008563.1 1433255 1434052 D transient receptor potential locus 1433255..1434052 Escherichia coli APEC O1 4492199 YP_852481.1 CDS ycjS NC_008563.1 1434062 1435117 D oxidoreductase YcjS 1434062..1435117 Escherichia coli APEC O1 4492200 YP_852482.1 CDS ycjT NC_008563.1 1435114 1437381 D transporter 1435114..1437381 Escherichia coli APEC O1 4492201 YP_852483.1 CDS ycjU NC_008563.1 1437378 1438037 D beta-phosphoglucomutase 1437378..1438037 Escherichia coli APEC O1 4491538 YP_852484.1 CDS ycjV NC_008563.1 1438051 1439133 D ABC transporter ATP-binding protein 1438051..1439133 Escherichia coli APEC O1 4491539 YP_852485.1 CDS ompG NC_008563.1 1439178 1440083 D outer membrane protein G 1439178..1440083 Escherichia coli APEC O1 4491540 YP_852486.1 CDS ycjW NC_008563.1 1440134 1441132 R transcriptional regulator YcjW complement(1440134..1441132) Escherichia coli APEC O1 4491541 YP_852487.1 CDS ycjX NC_008563.1 1441216 1442685 D hypothetical protein 1441216..1442685 Escherichia coli APEC O1 4491542 YP_852488.1 CDS ycjF NC_008563.1 1442682 1443743 D hypothetical protein 1442682..1443743 Escherichia coli APEC O1 4491543 YP_852489.1 CDS tyrR NC_008563.1 1443891 1445432 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1443891..1445432 Escherichia coli APEC O1 4491544 YP_852490.1 CDS tpx NC_008563.1 1445476 1445982 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1445476..1445982) Escherichia coli APEC O1 4491545 YP_852491.1 CDS ycjG NC_008563.1 1446101 1447066 D hypothetical protein 1446101..1447066 Escherichia coli APEC O1 4491546 YP_852492.1 CDS ycjI NC_008563.1 1447041 1447769 R murein peptide amidase A complement(1447041..1447769) Escherichia coli APEC O1 4491547 YP_852493.1 CDS APECO1_480 NC_008563.1 1448060 1448698 R hypothetical protein complement(1448060..1448698) Escherichia coli APEC O1 4491548 YP_852494.1 CDS ycjY NC_008563.1 1448769 1449701 R hypothetical protein complement(1448769..1449701) Escherichia coli APEC O1 4491549 YP_852495.1 CDS ycjZ NC_008563.1 1449827 1450726 D transcriptional regulator YcjZ 1449827..1450726 Escherichia coli APEC O1 4491550 YP_852496.1 CDS mppA NC_008563.1 1451042 1452676 D periplasmic murein peptide-binding protein 1451042..1452676 Escherichia coli APEC O1 4491551 YP_852497.1 CDS ynaI NC_008563.1 1452727 1453758 R hypothetical protein complement(1452727..1453758) Escherichia coli APEC O1 4491552 YP_852498.1 CDS ynaJ NC_008563.1 1454002 1454259 D hypothetical protein 1454002..1454259 Escherichia coli APEC O1 4491553 YP_852499.1 CDS APECO1_486 NC_008563.1 1454309 1455259 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1454309..1455259) Escherichia coli APEC O1 4491554 YP_852500.1 CDS fnr NC_008563.1 1455411 1456205 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1455411..1456205) Escherichia coli APEC O1 4491555 YP_852501.1 CDS ogt NC_008563.1 1456358 1456873 R O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1456358..1456873) Escherichia coli APEC O1 4491556 YP_852502.1 CDS APECO1_489 NC_008563.1 1457404 1458219 R hypothetical protein complement(1457404..1458219) Escherichia coli APEC O1 4495671 YP_852503.1 CDS hlyD NC_008563.1 1458313 1459344 D secretion protein 1458313..1459344 Escherichia coli APEC O1 4495672 YP_852504.1 CDS APECO1_491 NC_008563.1 1459341 1460855 D transporter 1459341..1460855 Escherichia coli APEC O1 4495673 YP_852505.1 CDS ydaL NC_008563.1 1461050 1461613 D hypothetical protein 1461050..1461613 Escherichia coli APEC O1 4495674 YP_852506.1 CDS ydaM NC_008563.1 1461634 1462926 R hypothetical protein complement(1461634..1462926) Escherichia coli APEC O1 4495675 YP_852507.1 CDS zntB NC_008563.1 1463121 1464104 D zinc transporter 1463121..1464104 Escherichia coli APEC O1 4495676 YP_852508.1 CDS dbpA NC_008563.1 1464582 1465955 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1464582..1465955 Escherichia coli APEC O1 4495678 YP_852509.1 CDS ydaO NC_008563.1 1466084 1467019 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1466084..1467019) Escherichia coli APEC O1 4495679 YP_852510.1 CDS intR NC_008563.1 1467071 1468306 R Rac prophage; integrase complement(1467071..1468306) Escherichia coli APEC O1 4495680 YP_852511.1 CDS ydaC NC_008563.1 1468623 1468883 R Rac prophage; hypothetical protein complement(1468623..1468883) Escherichia coli APEC O1 4495682 YP_852512.1 CDS recT NC_008563.1 1469055 1469921 R recombination and repair protein RecT complement(1469055..1469921) Escherichia coli APEC O1 4495683 YP_852513.1 CDS recE NC_008563.1 1469857 1472457 R The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC.; exonuclease VIII complement(1469857..1472457) Escherichia coli APEC O1 4495684 YP_852514.1 CDS racC NC_008563.1 1472559 1472882 R Rac prophage hypothetical protein; hypothetical protein complement(1472559..1472882) Escherichia coli APEC O1 4495685 YP_852515.1 CDS sieB NC_008563.1 1473608 1474219 D prophage CP-933R superinfection exclusion protein 1473608..1474219 Escherichia coli APEC O1 4495686 YP_852516.1 CDS APECO1_503 NC_008563.1 1474820 1475239 R regulator complement(1474820..1475239) Escherichia coli APEC O1 4495687 YP_852517.1 CDS ydaT NC_008563.1 1475575 1475997 D Rac prophage hypothetical protein 1475575..1475997 Escherichia coli APEC O1 4495688 YP_852518.1 CDS APECO1_505 NC_008563.1 1476010 1476870 D hypothetical protein 1476010..1476870 Escherichia coli APEC O1 4495689 YP_852519.1 CDS ydaV NC_008563.1 1476877 1477623 D replication protein 1476877..1477623 Escherichia coli APEC O1 4495690 YP_852520.1 CDS APECO1_507 NC_008563.1 1477595 1478407 D transcription regulatory protein 1477595..1478407 Escherichia coli APEC O1 4492202 YP_852521.1 CDS APECO1_508 NC_008563.1 1478423 1478839 D hypothetical protein 1478423..1478839 Escherichia coli APEC O1 4492203 YP_852522.1 CDS APECO1_509 NC_008563.1 1479003 1479689 D hypothetical protein 1479003..1479689 Escherichia coli APEC O1 4492204 YP_852523.1 CDS APECO1_510 NC_008563.1 1480490 1480975 D bacteriophage protein 1480490..1480975 Escherichia coli APEC O1 4492205 YP_852524.1 CDS APECO1_511 NC_008563.1 1481483 1482082 D hypothetical protein 1481483..1482082 Escherichia coli APEC O1 4492206 YP_852525.1 CDS APECO1_512 NC_008563.1 1482249 1482905 D antitermination protein 1482249..1482905 Escherichia coli APEC O1 4492207 YP_852526.1 CDS APECO1_513 NC_008563.1 1484111 1484413 D phage lysis protein 1484111..1484413 Escherichia coli APEC O1 4492208 YP_852527.1 CDS APECO1_514 NC_008563.1 1484413 1484910 D phage-related lysozyme (muraminidase) 1484413..1484910 Escherichia coli APEC O1 4492209 YP_852528.1 CDS APECO1_515 NC_008563.1 1484895 1485371 D hypothetical protein 1484895..1485371 Escherichia coli APEC O1 4492210 YP_852529.1 CDS trkG NC_008563.1 1485509 1486966 D Rac prophage; potassium transporter subunit 1485509..1486966 Escherichia coli APEC O1 4492211 YP_852530.1 CDS APECO1_517 NC_008563.1 1487104 1487895 D ParB-like; transcriptional regulator 1487104..1487895 Escherichia coli APEC O1 4492212 YP_852531.1 CDS APECO1_518 NC_008563.1 1487867 1488820 D hypothetical protein 1487867..1488820 Escherichia coli APEC O1 4492213 YP_852532.1 CDS APECO1_519 NC_008563.1 1488756 1489007 D hypothetical protein 1488756..1489007 Escherichia coli APEC O1 4492214 YP_852533.1 CDS APECO1_520 NC_008563.1 1489347 1490105 D hypothetical protein 1489347..1490105 Escherichia coli APEC O1 4492215 YP_852534.1 CDS APECO1_521 NC_008563.1 1490077 1491387 D phage terminase 1490077..1491387 Escherichia coli APEC O1 4492216 YP_852535.1 CDS APECO1_522 NC_008563.1 1491390 1492796 D chemotaxis protein; hypothetical protein 1491390..1492796 Escherichia coli APEC O1 4492217 YP_852536.1 CDS APECO1_523 NC_008563.1 1492777 1493892 D hypothetical protein 1492777..1493892 Escherichia coli APEC O1 4492218 YP_852537.1 CDS APECO1_524 NC_008563.1 1493925 1494761 D hypothetical protein 1493925..1494761 Escherichia coli APEC O1 4492219 YP_852538.1 CDS APECO1_525 NC_008563.1 1494791 1495999 D hypothetical protein 1494791..1495999 Escherichia coli APEC O1 4492220 YP_852539.1 CDS APECO1_526 NC_008563.1 1496270 1496665 D hypothetical protein 1496270..1496665 Escherichia coli APEC O1 4493734 YP_852540.1 CDS APECO1_527 NC_008563.1 1496662 1497048 D hypothetical protein 1496662..1497048 Escherichia coli APEC O1 4493735 YP_852541.1 CDS APECO1_528 NC_008563.1 1497049 1497429 D hypothetical protein 1497049..1497429 Escherichia coli APEC O1 4493736 YP_852542.1 CDS APECO1_529 NC_008563.1 1497426 1497818 D hypothetical protein 1497426..1497818 Escherichia coli APEC O1 4493737 YP_852543.1 CDS APECO1_530 NC_008563.1 1497845 1498807 D hypothetical protein 1497845..1498807 Escherichia coli APEC O1 4493738 YP_852544.1 CDS ydaY NC_008563.1 1498856 1499317 D Rac prophage hypothetical protein 1498856..1499317 Escherichia coli APEC O1 4493739 YP_852545.1 CDS ynaA NC_008563.1 1499789 1503022 D Rac prophage; tail protein 1499789..1503022 Escherichia coli APEC O1 4493740 YP_852546.1 CDS APECO1_533 NC_008563.1 1503015 1503353 D minor tail protein 1503015..1503353 Escherichia coli APEC O1 4493741 YP_852547.1 CDS APECO1_5332 NC_008563.1 1503353 1504051 D minor tail protein 1503353..1504051 Escherichia coli APEC O1 4493742 YP_852548.1 CDS APECO1_534 NC_008563.1 1504056 1504799 D tail fiber component K of prophage 1504056..1504799 Escherichia coli APEC O1 4493743 YP_852549.1 CDS APECO1_535 NC_008563.1 1504697 1505344 D tail component of prophage 1504697..1505344 Escherichia coli APEC O1 4493744 YP_852550.1 CDS APECO1_536 NC_008563.1 1505405 1508803 D tail component of prophage 1505405..1508803 Escherichia coli APEC O1 4493745 YP_852551.1 CDS APECO1_537 NC_008563.1 1508871 1509470 D outer membrane protein of prophage 1508871..1509470 Escherichia coli APEC O1 4493746 YP_852552.1 CDS APECO1_538 NC_008563.1 1509529 1511910 D tail fiber protein 1509529..1511910 Escherichia coli APEC O1 4493747 YP_852553.1 CDS APECO1_539 NC_008563.1 1511910 1512191 D hypothetical protein 1511910..1512191 Escherichia coli APEC O1 4493748 YP_852554.1 CDS APECO1_540 NC_008563.1 1512201 1512905 D hypothetical protein 1512201..1512905 Escherichia coli APEC O1 4493749 YP_852555.1 CDS APECO1_541 NC_008563.1 1512916 1513206 D hypothetical protein 1512916..1513206 Escherichia coli APEC O1 4493750 YP_852556.1 CDS cdtA NC_008563.1 1513719 1514432 D cytolethal distending toxin type IV subunit A 1513719..1514432 Escherichia coli APEC O1 4493751 YP_852557.1 CDS cdtB NC_008563.1 1514429 1515250 D cytolethal distending toxin type IV subunit B 1514429..1515250 Escherichia coli APEC O1 4493752 YP_852558.1 CDS cdtC NC_008563.1 1515247 1515819 D cytolethal distending toxin type IV subunit C 1515247..1515819 Escherichia coli APEC O1 4493753 YP_852559.1 CDS APECO1_545 NC_008563.1 1515889 1517373 R hypothetical protein complement(1515889..1517373) Escherichia coli APEC O1 4492620 YP_852560.2 CDS APECO1_546 NC_008563.1 1517558 1518508 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(1517558..1518508) Escherichia coli APEC O1 4492621 YP_852561.1 CDS APECO1_547 NC_008563.1 1518815 1519165 R hypothetical protein complement(1518815..1519165) Escherichia coli APEC O1 4492622 YP_852562.1 CDS APECO1_548 NC_008563.1 1519398 1519706 R integrase complement(1519398..1519706) Escherichia coli APEC O1 4492623 YP_852563.1 CDS APECO1_549 NC_008563.1 1521673 1522179 R filament protein complement(1521673..1522179) Escherichia coli APEC O1 4492624 YP_852564.1 CDS ompN NC_008563.1 1522248 1523381 R outer membrane pore protein N, non-specific complement(1522248..1523381) Escherichia coli APEC O1 4492625 YP_852565.1 CDS ydbK NC_008563.1 1523747 1527271 R pyruvate-flavodoxin oxidoreductase complement(1523747..1527271) Escherichia coli APEC O1 4492626 YP_852566.1 CDS APECO1_552 NC_008563.1 1527342 1527782 R hypothetical protein complement(1527342..1527782) Escherichia coli APEC O1 4492627 YP_852567.1 CDS hslJ NC_008563.1 1527808 1528230 R heat-inducible protein complement(1527808..1528230) Escherichia coli APEC O1 4492628 YP_852568.1 CDS ldhA NC_008563.1 1528341 1529330 R D-lactate dehydrogenase complement(1528341..1529330) Escherichia coli APEC O1 4492629 YP_852569.1 CDS ydbH NC_008563.1 1529538 1532177 D hypothetical protein 1529538..1532177 Escherichia coli APEC O1 4492630 YP_852570.1 CDS ydbL NC_008563.1 1532292 1532693 D hypothetical protein 1532292..1532693 Escherichia coli APEC O1 4492631 YP_852571.1 CDS entS NC_008563.1 1533069 1540061 D EntS/YbdA MFS transporter 1533069..1540061 Escherichia coli APEC O1 4492632 YP_852572.1 CDS APECO1_558 NC_008563.1 1540281 1541141 D oxidoreductase 1540281..1541141 Escherichia coli APEC O1 4492633 YP_852573.1 CDS ynbA NC_008563.1 1541440 1542045 D hypothetical protein 1541440..1542045 Escherichia coli APEC O1 4492634 YP_852574.1 CDS ynbB NC_008563.1 1542045 1542941 D phosphatidate cytidylyltransferase 1542045..1542941 Escherichia coli APEC O1 4492635 YP_852575.1 CDS ynbC NC_008563.1 1542957 1544714 D methylase 1542957..1544714 Escherichia coli APEC O1 4492636 YP_852576.1 CDS ynbD NC_008563.1 1544629 1546020 D hypothetical protein 1544629..1546020 Escherichia coli APEC O1 4492637 YP_852577.1 CDS APECO1_563 NC_008563.1 1546005 1546667 D hypothetical protein 1546005..1546667 Escherichia coli APEC O1 4492638 YP_852578.1 CDS hrpA NC_008563.1 1546880 1550782 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1546880..1550782 Escherichia coli APEC O1 4491656 YP_852579.1 CDS ydcF NC_008563.1 1551055 1551855 D hypothetical protein 1551055..1551855 Escherichia coli APEC O1 4491657 YP_852580.1 CDS aldA NC_008563.1 1552052 1553491 D NAD-linked; aldehyde dehydrogenase A 1552052..1553491 Escherichia coli APEC O1 4491658 YP_852581.1 CDS APECO1_567 NC_008563.1 1553533 1554534 R glyceraldehyde 3-phosphate dehydrogenase A complement(1553533..1554534) Escherichia coli APEC O1 4491659 YP_852582.2 CDS cybB NC_008563.1 1554723 1555253 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1554723..1555253 Escherichia coli APEC O1 4491660 YP_852583.1 CDS APECO1_569 NC_008563.1 1555829 1556299 D hypothetical protein 1555829..1556299 Escherichia coli APEC O1 4491661 YP_852584.1 CDS ydcI NC_008563.1 1556337 1557401 R transcriptional regulator YdcI complement(1556337..1557401) Escherichia coli APEC O1 4491662 YP_852585.1 CDS ydcJ NC_008563.1 1557477 1558820 D hypothetical protein 1557477..1558820 Escherichia coli APEC O1 4491663 YP_852586.1 CDS mdoD NC_008563.1 1559045 1560700 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1559045..1560700 Escherichia coli APEC O1 4491664 YP_852587.1 CDS rimL NC_008563.1 1561127 1561666 D ribosomal-protein-L7/L12-serine acetyltransferase 1561127..1561666 Escherichia coli APEC O1 4491665 YP_852588.1 CDS ydcK NC_008563.1 1561658 1562638 R hypothetical protein complement(1561658..1562638) Escherichia coli APEC O1 4491666 YP_852589.1 CDS tehA NC_008563.1 1562654 1563754 D potassium-tellurite ethidium and proflavin transporter 1562654..1563754 Escherichia coli APEC O1 4491668 YP_852590.1 CDS tehB NC_008563.1 1563751 1564344 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1563751..1564344 Escherichia coli APEC O1 4491669 YP_852591.1 CDS APECO1_577 NC_008563.1 1564647 1565315 D hypothetical protein 1564647..1565315 Escherichia coli APEC O1 4491670 YP_852592.1 CDS ydcO NC_008563.1 1565350 1566645 R hypothetical protein complement(1565350..1566645) Escherichia coli APEC O1 4491671 YP_852593.1 CDS ydcN NC_008563.1 1566614 1567150 D hypothetical protein 1566614..1567150 Escherichia coli APEC O1 4491672 YP_852594.1 CDS ydcP NC_008563.1 1567181 1569184 D protease YdcP 1567181..1569184 Escherichia coli APEC O1 4491673 YP_852595.1 CDS ydcR NC_008563.1 1570000 1571406 D fused DNA-binding transcriptional regulator/ amino transferase 1570000..1571406 Escherichia coli APEC O1 4491674 YP_852596.1 CDS ydcS NC_008563.1 1571651 1572796 D ABC transporter substrate-binding protein 1571651..1572796 Escherichia coli APEC O1 4491675 YP_852597.1 CDS ydcT NC_008563.1 1572814 1573827 D ABC transporter ATP-binding protein 1572814..1573827 Escherichia coli APEC O1 4494894 YP_852598.1 CDS ydcU NC_008563.1 1573828 1574769 D ABC transporter permease 1573828..1574769 Escherichia coli APEC O1 4494895 YP_852599.1 CDS APECO1_585 NC_008563.1 1574759 1575553 D transport system permease 1574759..1575553 Escherichia coli APEC O1 4494896 YP_852600.1 CDS ydcW NC_008563.1 1575575 1576999 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1575575..1576999 Escherichia coli APEC O1 4494897 YP_852601.1 CDS APECO1_587 NC_008563.1 1577188 1577466 R hypothetical protein complement(1577188..1577466) Escherichia coli APEC O1 4494898 YP_852602.1 CDS ydcZ NC_008563.1 1577879 1578328 R hypothetical protein complement(1577879..1578328) Escherichia coli APEC O1 4494899 YP_852603.1 CDS yncA NC_008563.1 1578325 1578843 R acyltransferase complement(1578325..1578843) Escherichia coli APEC O1 4494900 YP_852604.1 CDS APECO1_590 NC_008563.1 1578836 1579177 D hypothetical protein 1578836..1579177 Escherichia coli APEC O1 4494901 YP_852605.1 CDS yncD NC_008563.1 1579324 1581426 R iron outer membrane transporter complement(1579324..1581426) Escherichia coli APEC O1 4494902 YP_852606.1 CDS yncE NC_008563.1 1581668 1582729 D hypothetical protein 1581668..1582729 Escherichia coli APEC O1 4494903 YP_852607.1 CDS ansP NC_008563.1 1582842 1584386 R L-asparagine permease complement(1582842..1584386) Escherichia coli APEC O1 4494904 YP_852608.1 CDS APECO1_594 NC_008563.1 1584798 1585208 D hypothetical protein 1584798..1585208 Escherichia coli APEC O1 4494905 YP_852609.1 CDS APECO1_595 NC_008563.1 1585749 1586033 D hypothetical protein 1585749..1586033 Escherichia coli APEC O1 4494906 YP_852610.1 CDS APECO1_596 NC_008563.1 1586052 1588457 D hypothetical protein 1586052..1588457 Escherichia coli APEC O1 4494907 YP_852611.1 CDS APECO1_597 NC_008563.1 1588417 1589208 D hypothetical protein 1588417..1589208 Escherichia coli APEC O1 4494908 YP_852612.1 CDS APECO1_598 NC_008563.1 1589261 1589980 D hypothetical protein 1589261..1589980 Escherichia coli APEC O1 4494909 YP_852613.1 CDS yddH NC_008563.1 1590911 1591480 R hypothetical protein complement(1590911..1591480) Escherichia coli APEC O1 4494910 YP_852614.1 CDS nhoA NC_008563.1 1591655 1592500 D N-hydroxyarylamine O-acetyltransferase 1591655..1592500 Escherichia coli APEC O1 4494911 YP_852615.1 CDS yddE NC_008563.1 1592596 1593489 R hypothetical protein complement(1592596..1593489) Escherichia coli APEC O1 4494912 YP_852616.1 CDS narV NC_008563.1 1593569 1594249 R respiratory nitrate reductase 2 gamma chain complement(1593569..1594249) Escherichia coli APEC O1 4494388 YP_852617.1 CDS narW NC_008563.1 1594246 1594941 R cryptic nitrate reductase 2 subunit delta complement(1594246..1594941) Escherichia coli APEC O1 4494389 YP_852618.1 CDS narY NC_008563.1 1594941 1596485 R cryptic nitrate reductase 2 subunit beta complement(1594941..1596485) Escherichia coli APEC O1 4494390 YP_852619.1 CDS narZ NC_008563.1 1596482 1600345 R respiratory nitrate reductase 2 alpha chain complement(1596482..1600345) Escherichia coli APEC O1 4494391 YP_852620.1 CDS narU NC_008563.1 1600317 1601723 R nitrite extrusion protein 2 complement(1600317..1601723) Escherichia coli APEC O1 4494392 YP_852621.1 CDS APECO1_607 NC_008563.1 1601978 1602859 R hypothetical protein complement(1601978..1602859) Escherichia coli APEC O1 4494393 YP_852622.1 CDS APECO1_608 NC_008563.1 1603265 1604335 R hypothetical protein complement(1603265..1604335) Escherichia coli APEC O1 4494394 YP_852623.1 CDS fdnG NC_008563.1 1603727 1606138 D FdnG subunit alpha of formate dehydrogenase-N 1603727..1606138 Escherichia coli APEC O1 4494395 YP_852625.1 CDS fdnI NC_008563.1 1607010 1607681 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1607010..1607681 Escherichia coli APEC O1 4494397 YP_852626.1 CDS APECO1_612 NC_008563.1 1607910 1608194 R hypothetical protein complement(1607910..1608194) Escherichia coli APEC O1 4494398 YP_852627.1 CDS APECO1_613 NC_008563.1 1608194 1608472 R addiction system protein; hypothetical protein complement(1608194..1608472) Escherichia coli APEC O1 4494399 YP_852628.1 CDS adhP NC_008563.1 1608658 1609698 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1608658..1609698) Escherichia coli APEC O1 4494400 YP_852629.2 CDS sfcA NC_008563.1 1609802 1611499 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1609802..1611499) Escherichia coli APEC O1 4494401 YP_852630.1 CDS APECO1_616 NC_008563.1 1611894 1612172 R biofilm-dependent modulation protein complement(1611894..1612172) Escherichia coli APEC O1 4494402 YP_852631.1 CDS osmC NC_008563.1 1612454 1612885 D osmotically inducible protein OsmC 1612454..1612885 Escherichia coli APEC O1 4494403 YP_852632.1 CDS APECO1_618 NC_008563.1 1613075 1615498 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1613075..1615498) Escherichia coli APEC O1 4494404 YP_852633.1 CDS yddW NC_008563.1 1616041 1617360 R lipoprotein YddW precursor complement(1616041..1617360) Escherichia coli APEC O1 4494405 YP_852634.1 CDS xasA NC_008563.1 1617491 1619026 R amino acid antiporter complement(1617491..1619026) Escherichia coli APEC O1 4494406 YP_852635.1 CDS gadA NC_008563.1 1619182 1620474 R glutamate decarboxylase complement(1619182..1620474) Escherichia coli APEC O1 4494407 YP_852636.1 CDS pqqL NC_008563.1 1620943 1623738 R zinc protease PqqL complement(1620943..1623738) Escherichia coli APEC O1 4493754 YP_852637.1 CDS yddB NC_008563.1 1623783 1626155 R hypothetical protein complement(1623783..1626155) Escherichia coli APEC O1 4493755 YP_852638.1 CDS yddA NC_008563.1 1626193 1627878 R ATP-binding component of a transport system complement(1626193..1627878) Escherichia coli APEC O1 4493756 YP_852639.1 CDS ydeM NC_008563.1 1628169 1629326 R hypothetical protein complement(1628169..1629326) Escherichia coli APEC O1 4493757 YP_852640.1 CDS ydeN NC_008563.1 1629378 1631060 R sulfatase complement(1629378..1631060) Escherichia coli APEC O1 4493758 YP_852641.1 CDS APECO1_627 NC_008563.1 1631462 1632223 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1631462..1632223) Escherichia coli APEC O1 4493759 YP_852642.1 CDS ydeP NC_008563.1 1632743 1635022 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase complement(1632743..1635022) Escherichia coli APEC O1 4493760 YP_852643.1 CDS fmlD NC_008563.1 1635361 1636275 R Fml fimbrial adhesin FmlD complement(1635361..1636275) Escherichia coli APEC O1 4493761 YP_852644.1 CDS ydeR NC_008563.1 1636335 1636838 R fimbrial-like adhesin protein complement(1636335..1636838) Escherichia coli APEC O1 4493762 YP_852645.1 CDS ydeS NC_008563.1 1636851 1637381 R fimbrial-like adhesin protein complement(1636851..1637381) Escherichia coli APEC O1 4493763 YP_852646.1 CDS APECO1_632 NC_008563.1 1637395 1640046 R outer membrane usher protein FimD complement(1637395..1640046) Escherichia coli APEC O1 4493764 YP_852647.1 CDS APECO1_633 NC_008563.1 1640088 1640807 R chaperone protein fimC precursor complement(1640088..1640807) Escherichia coli APEC O1 4493765 YP_852648.1 CDS fmlA NC_008563.1 1641160 1641723 R Fml fimbriae subunit complement(1641160..1641723) Escherichia coli APEC O1 4493766 YP_852649.1 CDS APECO1_635 NC_008563.1 1642499 1643281 R hypothetical protein complement(1642499..1643281) Escherichia coli APEC O1 4493767 YP_852650.1 CDS APECO1_636 NC_008563.1 1643391 1643648 D hypothetical protein 1643391..1643648 Escherichia coli APEC O1 4493768 YP_852651.1 CDS hipA NC_008563.1 1643907 1645286 R regulator with HipB complement(1643907..1645286) Escherichia coli APEC O1 4493769 YP_852652.1 CDS hipB NC_008563.1 1645229 1645495 R DNA-binding transcriptional regulator HipB complement(1645229..1645495) Escherichia coli APEC O1 4493770 YP_852653.1 CDS tam NC_008563.1 1645803 1646561 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1645803..1646561 Escherichia coli APEC O1 4493771 YP_852654.1 CDS APECO1_640 NC_008563.1 1646565 1647530 R hypothetical protein complement(1646565..1647530) Escherichia coli APEC O1 4493772 YP_852655.1 CDS uxaB NC_008563.1 1647676 1649127 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1647676..1649127) Escherichia coli APEC O1 4493398 YP_852656.1 CDS yneF NC_008563.1 1649354 1650772 R hypothetical protein complement(1649354..1650772) Escherichia coli APEC O1 4493399 YP_852657.1 CDS yneG NC_008563.1 1650911 1651270 R hypothetical protein complement(1650911..1651270) Escherichia coli APEC O1 4493400 YP_852658.1 CDS yneH NC_008563.1 1651270 1652196 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1651270..1652196) Escherichia coli APEC O1 4493401 YP_852659.1 CDS yneI NC_008563.1 1652260 1653672 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(1652260..1653672) Escherichia coli APEC O1 4493402 YP_852660.1 CDS yneJ NC_008563.1 1653749 1654630 D aldehyde-dehydrogenase like protein YneI 1653749..1654630 Escherichia coli APEC O1 4493403 YP_852661.1 CDS sotB NC_008563.1 1654969 1656159 D sugar efflux transporter 1654969..1656159 Escherichia coli APEC O1 4493404 YP_852662.1 CDS marC NC_008563.1 1656184 1656849 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1656184..1656849) Escherichia coli APEC O1 4493405 YP_852663.1 CDS marR NC_008563.1 1657061 1657495 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1657061..1657495 Escherichia coli APEC O1 4493406 YP_852664.1 CDS marA NC_008563.1 1657510 1657899 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1657510..1657899 Escherichia coli APEC O1 4493407 YP_852665.1 CDS celA NC_008563.1 1658206 1659675 R converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase complement(1658206..1659675) Escherichia coli APEC O1 4493408 YP_852666.1 CDS yieC NC_008563.1 1659669 1661342 R outer membrane protein YieC complement(1659669..1661342) Escherichia coli APEC O1 4493409 YP_852667.1 CDS APECO1_652 NC_008563.1 1661397 1661711 R PTS system cellobiose-specific transporter subunit IIA complement(1661397..1661711) Escherichia coli APEC O1 4493410 YP_852668.1 CDS APECO1_653 NC_008563.1 1661736 1663058 R hypothetical protein complement(1661736..1663058) Escherichia coli APEC O1 4493411 YP_852669.1 CDS APECO1_654 NC_008563.1 1663173 1663484 R PTS system cellobiose-specific transporter subunit IIB complement(1663173..1663484) Escherichia coli APEC O1 4493412 YP_852670.1 CDS APECO1_655 NC_008563.1 1663683 1664381 D transcriptional regulator 1663683..1664381 Escherichia coli APEC O1 4493413 YP_852671.2 CDS ydeD NC_008563.1 1664426 1665325 R O-acetylserine/cysteine export protein complement(1664426..1665325) Escherichia coli APEC O1 4493414 YP_852672.1 CDS ydeE NC_008563.1 1665520 1666707 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1665520..1666707 Escherichia coli APEC O1 4493415 YP_852673.1 CDS ydeH NC_008563.1 1667148 1668044 R hypothetical protein complement(1667148..1668044) Escherichia coli APEC O1 4493416 YP_852674.1 CDS dcp NC_008563.1 1668546 1670591 R dipeptidyl carboxypeptidase II complement(1668546..1670591) Escherichia coli APEC O1 4493417 YP_852675.1 CDS ydfG NC_008563.1 1670728 1671474 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1670728..1671474 Escherichia coli APEC O1 4494369 YP_852676.1 CDS APECO1_660 NC_008563.1 1671563 1672249 D hypothetical protein 1671563..1672249 Escherichia coli APEC O1 4494370 YP_852678.1 CDS APECO1_662 NC_008563.1 1672665 1674125 R oxidoreductase complement(1672665..1674125) Escherichia coli APEC O1 4494372 YP_852679.2 CDS rspB NC_008563.1 1674626 1675645 R dehydrogenase complement(1674626..1675645) Escherichia coli APEC O1 4494373 YP_852680.1 CDS rspA NC_008563.1 1675657 1676904 R starvation sensing protein RspA complement(1675657..1676904) Escherichia coli APEC O1 4494374 YP_852681.1 CDS ynfA NC_008563.1 1677077 1677412 R hypothetical protein complement(1677077..1677412) Escherichia coli APEC O1 4494375 YP_852682.1 CDS ynfB NC_008563.1 1677538 1677879 D hypothetical protein 1677538..1677879 Escherichia coli APEC O1 4494376 YP_852683.1 CDS APECO1_667 NC_008563.1 1677914 1678474 D spermidine N1-acetyltransferase 1677914..1678474 Escherichia coli APEC O1 4494377 YP_852684.1 CDS ynfC NC_008563.1 1678477 1679223 R hypothetical protein complement(1678477..1679223) Escherichia coli APEC O1 4494378 YP_852685.1 CDS ynfD NC_008563.1 1679253 1679600 D hypothetical protein 1679253..1679600 Escherichia coli APEC O1 4494379 YP_852686.1 CDS ynfE NC_008563.1 1679799 1682225 D dimethyl sulfoxide reductase subunit YnfE 1679799..1682225 Escherichia coli APEC O1 4494380 YP_852687.1 CDS ynfF NC_008563.1 1682283 1684709 D dimethyl sulfoxide reductase subunit YnfF 1682283..1684709 Escherichia coli APEC O1 4494381 YP_852688.1 CDS dmsB NC_008563.1 1684720 1685337 D dimethyl sulfoxide reductase, anaerobic subunit B 1684720..1685337 Escherichia coli APEC O1 4494382 YP_852689.1 CDS ynfH NC_008563.1 1685099 1686193 D oxidoreductase, membrane subunit 1685099..1686193 Escherichia coli APEC O1 4494383 YP_852690.1 CDS ynfI NC_008563.1 1686227 1686850 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1686227..1686850 Escherichia coli APEC O1 4494384 YP_852691.1 CDS ynfJ NC_008563.1 1686988 1688229 D voltage-gated ClC-type chloride channel ClcB 1686988..1688229 Escherichia coli APEC O1 4494385 YP_852692.1 CDS ynfK NC_008563.1 1688182 1688889 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1688182..1688889) Escherichia coli APEC O1 4494386 YP_852693.1 CDS mlc NC_008563.1 1689002 1690222 R Mlc protein complement(1689002..1690222) Escherichia coli APEC O1 4494387 YP_852694.1 CDS ynfL NC_008563.1 1690357 1691250 R transcriptional regulator complement(1690357..1691250) Escherichia coli APEC O1 4492086 YP_852695.1 CDS ynfM NC_008563.1 1691357 1692610 D transporter 1691357..1692610 Escherichia coli APEC O1 4492087 YP_852696.1 CDS asr NC_008563.1 1693008 1693343 D required for growth and survival under moderately acid conditions; acid shock protein 1693008..1693343 Escherichia coli APEC O1 4492088 YP_852697.1 CDS ydgD NC_008563.1 1693619 1694440 D protease 1693619..1694440 Escherichia coli APEC O1 4492089 YP_852698.1 CDS APECO1_682 NC_008563.1 1694479 1694808 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1694479..1694808) Escherichia coli APEC O1 4492090 YP_852699.1 CDS ydgF NC_008563.1 1694795 1695160 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1694795..1695160) Escherichia coli APEC O1 4492091 YP_852700.1 CDS tqsA NC_008563.1 1695571 1696605 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1695571..1696605 Escherichia coli APEC O1 4492092 YP_852701.1 CDS pntB NC_008563.1 1696630 1698018 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1696630..1698018) Escherichia coli APEC O1 4492093 YP_852702.1 CDS pntA NC_008563.1 1698029 1699615 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1698029..1699615) Escherichia coli APEC O1 4492094 YP_852703.1 CDS ydgH NC_008563.1 1700085 1701029 D hypothetical protein 1700085..1701029 Escherichia coli APEC O1 4492095 YP_852704.1 CDS ydgI NC_008563.1 1701215 1702597 D arginine/ornithine antiporter 1701215..1702597 Escherichia coli APEC O1 4492096 YP_852705.1 CDS ydgB NC_008563.1 1702634 1703356 D short chain dehydrogenase 1702634..1703356 Escherichia coli APEC O1 4492097 YP_852706.1 CDS ydgC NC_008563.1 1703353 1703688 R hypothetical protein complement(1703353..1703688) Escherichia coli APEC O1 4492098 YP_852707.1 CDS rstA NC_008563.1 1703781 1704536 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1703781..1704536 Escherichia coli APEC O1 4492099 YP_852708.1 CDS rstB NC_008563.1 1704540 1705841 D sensor protein RstB 1704540..1705841 Escherichia coli APEC O1 4492100 YP_852709.1 CDS tus NC_008563.1 1705905 1706846 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1705905..1706846 Escherichia coli APEC O1 4492101 YP_852710.1 CDS fumC NC_008563.1 1706843 1708246 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1706843..1708246) Escherichia coli APEC O1 4492102 YP_852711.1 CDS fumA NC_008563.1 1708389 1710035 R fumarate hydratase, aerobic class I complement(1708389..1710035) Escherichia coli APEC O1 4493645 YP_852712.1 CDS manA NC_008563.1 1710234 1711409 D mannose-6-phosphate isomerase 1710234..1711409 Escherichia coli APEC O1 4493646 YP_852713.1 CDS APECO1_697 NC_008563.1 1711510 1713018 D hypothetical protein 1711510..1713018 Escherichia coli APEC O1 4493647 YP_852714.1 CDS uidC NC_008563.1 1713063 1714328 R outer membrane porin protein complement(1713063..1714328) Escherichia coli APEC O1 4493648 YP_852715.1 CDS uidB NC_008563.1 1714367 1715740 R glucuronide transporter complement(1714367..1715740) Escherichia coli APEC O1 4493649 YP_852716.1 CDS uidA NC_008563.1 1715737 1717548 R beta-D-glucuronidase complement(1715737..1717548) Escherichia coli APEC O1 4493650 YP_852717.1 CDS uidR NC_008563.1 1717938 1718528 R repressor for uid operon complement(1717938..1718528) Escherichia coli APEC O1 4493651 YP_852718.1 CDS hdhA NC_008563.1 1718757 1719524 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1718757..1719524) Escherichia coli APEC O1 4493652 YP_852719.1 CDS malI NC_008563.1 1719636 1720664 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1719636..1720664) Escherichia coli APEC O1 4493653 YP_852720.1 CDS malX NC_008563.1 1720839 1722431 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1720839..1722431 Escherichia coli APEC O1 4493654 YP_852721.1 CDS malY NC_008563.1 1722441 1723613 D bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon 1722441..1723613 Escherichia coli APEC O1 4493655 YP_852722.1 CDS add NC_008563.1 1723717 1724718 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1723717..1724718 Escherichia coli APEC O1 4493656 YP_852723.1 CDS ydgJ NC_008563.1 1724754 1725833 R oxidoreductase complement(1724754..1725833) Escherichia coli APEC O1 4493657 YP_852724.1 CDS APECO1_708 NC_008563.1 1726251 1726514 D hypothetical protein 1726251..1726514 Escherichia coli APEC O1 4493658 YP_852725.1 CDS ydgK NC_008563.1 1726736 1727176 D hypothetical protein 1726736..1727176 Escherichia coli APEC O1 4493659 YP_852726.1 CDS rnfA NC_008563.1 1727253 1727834 D Na(+)-translocating NADH-quinone reductase subunit E 1727253..1727834 Escherichia coli APEC O1 4493660 YP_852727.1 CDS rnfB NC_008563.1 1727834 1728412 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1727834..1728412 Escherichia coli APEC O1 4493661 YP_852728.1 CDS rnfC NC_008563.1 1728405 1730531 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1728405..1730531 Escherichia coli APEC O1 4493662 YP_852729.1 CDS rnfD NC_008563.1 1730532 1731590 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1730532..1731590 Escherichia coli APEC O1 4493663 YP_852730.1 CDS rnfG NC_008563.1 1731594 1732214 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1731594..1732214 Escherichia coli APEC O1 4491616 YP_852731.1 CDS rnfE NC_008563.1 1732218 1732913 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1732218..1732913 Escherichia coli APEC O1 4491617 YP_852732.1 CDS nth NC_008563.1 1732913 1733548 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1732913..1733548 Escherichia coli APEC O1 4491618 YP_852733.1 CDS tppB NC_008563.1 1734159 1735661 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1734159..1735661 Escherichia coli APEC O1 4491619 YP_852734.1 CDS gst NC_008563.1 1735766 1736371 D glutathionine S-transferase 1735766..1736371 Escherichia coli APEC O1 4491620 YP_852735.1 CDS pdxY NC_008563.1 1736415 1737278 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1736415..1737278) Escherichia coli APEC O1 4491621 YP_852736.1 CDS tyrS NC_008563.1 1737337 1738623 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1737337..1738623) Escherichia coli APEC O1 4491622 YP_852737.1 CDS pdxH NC_008563.1 1738740 1739396 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1738740..1739396) Escherichia coli APEC O1 4491623 YP_852738.1 CDS ydhA NC_008563.1 1739455 1739784 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1739455..1739784) Escherichia coli APEC O1 4491624 YP_852739.1 CDS anmK NC_008563.1 1739882 1740991 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1739882..1740991) Escherichia coli APEC O1 4491625 YP_852740.1 CDS slyB NC_008563.1 1741265 1741732 D outer membrane lipoprotein SlyB 1741265..1741732 Escherichia coli APEC O1 4491626 YP_852741.1 CDS slyA NC_008563.1 1741779 1742219 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1741779..1742219) Escherichia coli APEC O1 4491627 YP_852742.1 CDS ydhJ NC_008563.1 1742644 1743387 D hypothetical protein 1742644..1743387 Escherichia coli APEC O1 4491628 YP_852743.1 CDS ydhK NC_008563.1 1743509 1745521 D hypothetical protein 1743509..1745521 Escherichia coli APEC O1 4491629 YP_852744.1 CDS sodC NC_008563.1 1745522 1746094 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1745522..1746094) Escherichia coli APEC O1 4491630 YP_852745.1 CDS ydhF NC_008563.1 1746124 1747020 R oxidoreductase YdhF complement(1746124..1747020) Escherichia coli APEC O1 4491631 YP_852746.1 CDS ydhM NC_008563.1 1747411 1748010 D DNA-binding transcriptional regulator 1747411..1748010 Escherichia coli APEC O1 4491632 YP_852747.1 CDS nemA NC_008563.1 1748047 1749144 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1748047..1749144 Escherichia coli APEC O1 4491633 YP_852748.1 CDS gloA NC_008563.1 1749225 1749632 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1749225..1749632 Escherichia coli APEC O1 4491634 YP_852749.1 CDS rnt NC_008563.1 1749735 1750382 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1749735..1750382 Escherichia coli APEC O1 4491635 YP_852750.1 CDS ydhO NC_008563.1 1750754 1751101 R hypothetical protein complement(1750754..1751101) Escherichia coli APEC O1 4492259 YP_852751.1 CDS sodB NC_008563.1 1752379 1752960 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1752379..1752960 Escherichia coli APEC O1 4492260 YP_852752.1 CDS ydhP NC_008563.1 1753106 1754275 R transporter complement(1753106..1754275) Escherichia coli APEC O1 4492261 YP_852753.1 CDS purR NC_008563.1 1754829 1755854 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1754829..1755854 Escherichia coli APEC O1 4492262 YP_852754.1 CDS ydhB NC_008563.1 1755851 1756783 R DNA-binding transcriptional regulator complement(1755851..1756783) Escherichia coli APEC O1 4492263 YP_852755.1 CDS ydhC NC_008563.1 1756896 1758107 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1756896..1758107 Escherichia coli APEC O1 4492264 YP_852756.1 CDS cfa NC_008563.1 1758398 1759546 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1758398..1759546 Escherichia coli APEC O1 4492265 YP_852757.1 CDS ribE NC_008563.1 1759586 1760227 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1759586..1760227) Escherichia coli APEC O1 4492266 YP_852758.1 CDS mdtK NC_008563.1 1760442 1761815 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1760442..1761815 Escherichia coli APEC O1 4492267 YP_852759.1 CDS ydhQ NC_008563.1 1761856 1763112 R hypothetical protein complement(1761856..1763112) Escherichia coli APEC O1 4492268 YP_852761.1 CDS ydhS NC_008563.1 1764117 1765067 D hypothetical protein 1764117..1765067 Escherichia coli APEC O1 4492270 YP_852762.1 CDS APECO1_747 NC_008563.1 1765368 1765721 D hypothetical protein 1765368..1765721 Escherichia coli APEC O1 4492271 YP_852763.1 CDS ydhT NC_008563.1 1765733 1766545 R hypothetical protein complement(1765733..1766545) Escherichia coli APEC O1 4492272 YP_852764.1 CDS ydhU NC_008563.1 1766549 1767334 R cytochrome complement(1766549..1767334) Escherichia coli APEC O1 4492273 YP_852765.1 CDS APECO1_750 NC_008563.1 1767331 1768050 R oxidoreductase Fe-S subunit complement(1767331..1768050) Escherichia coli APEC O1 4492274 YP_852766.1 CDS ydhW NC_008563.1 1768063 1768710 R hypothetical protein complement(1768063..1768710) Escherichia coli APEC O1 4492275 YP_852767.2 CDS ydhV NC_008563.1 1768714 1770816 R oxidoreductase complement(1768714..1770816) Escherichia coli APEC O1 4492276 YP_852768.1 CDS ydhY NC_008563.1 1770837 1771463 R hypothetical protein complement(1770837..1771463) Escherichia coli APEC O1 4492277 YP_852769.1 CDS pykF NC_008563.1 1772469 1774097 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1772469..1774097 Escherichia coli APEC O1 4493418 YP_852770.1 CDS ynhG NC_008563.1 1774707 1775711 R hypothetical protein complement(1774707..1775711) Escherichia coli APEC O1 4493420 YP_852771.1 CDS sufE NC_008563.1 1775860 1776276 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1775860..1776276) Escherichia coli APEC O1 4493421 YP_852772.1 CDS sufS NC_008563.1 1776289 1777509 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1776289..1777509) Escherichia coli APEC O1 4493422 YP_852773.1 CDS sufD NC_008563.1 1777506 1778777 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1777506..1778777) Escherichia coli APEC O1 4493423 YP_852774.1 CDS sufC NC_008563.1 1778752 1779498 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1778752..1779498) Escherichia coli APEC O1 4493424 YP_852775.1 CDS sufB NC_008563.1 1779508 1781034 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1779508..1781034) Escherichia coli APEC O1 4493425 YP_852776.1 CDS sufA NC_008563.1 1781004 1781372 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1781004..1781372) Escherichia coli APEC O1 4493426 YP_852777.1 CDS ydiH NC_008563.1 1781921 1782190 R hypothetical protein complement(1781921..1782190) Escherichia coli APEC O1 4493427 YP_852778.1 CDS ydiI NC_008563.1 1782209 1782619 R hypothetical protein complement(1782209..1782619) Escherichia coli APEC O1 4493428 YP_852779.1 CDS ydiJ NC_008563.1 1782616 1785672 R FAD-linked oxidoreductase complement(1782616..1785672) Escherichia coli APEC O1 4493429 YP_852780.1 CDS APECO1_765 NC_008563.1 1785886 1786998 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; hypothetical protein 1785886..1786998 Escherichia coli APEC O1 4493430 YP_852781.1 CDS ydiM NC_008563.1 1787883 1789097 D transporter 1787883..1789097 Escherichia coli APEC O1 4493431 YP_852782.1 CDS ydiN NC_008563.1 1789318 1790589 D transporter 1789318..1790589 Escherichia coli APEC O1 4493432 YP_852783.1 CDS ydiB NC_008563.1 1790601 1791467 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1790601..1791467 Escherichia coli APEC O1 4493433 YP_852784.1 CDS aroD NC_008563.1 1791498 1792256 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1791498..1792256 Escherichia coli APEC O1 4493434 YP_852785.1 CDS ydiF NC_008563.1 1792402 1793997 D fused acetyl-CoA:acetoacetyl-CoA transferase 1792402..1793997 Escherichia coli APEC O1 4493435 YP_852786.2 CDS ydiO NC_008563.1 1794011 1795162 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1794011..1795162 Escherichia coli APEC O1 4493436 YP_852787.1 CDS ydiP NC_008563.1 1795205 1796116 R DNA-binding transcriptional regulator complement(1795205..1796116) Escherichia coli APEC O1 4493437 YP_852788.1 CDS ydiQ NC_008563.1 1796411 1797196 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1796411..1797196 Escherichia coli APEC O1 4492036 YP_852789.1 CDS ydiR NC_008563.1 1797216 1798154 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1797216..1798154 Escherichia coli APEC O1 4492037 YP_852790.1 CDS ydiS NC_008563.1 1798209 1799498 D hypothetical protein 1798209..1799498 Escherichia coli APEC O1 4492038 YP_852791.1 CDS ydiT NC_008563.1 1799495 1799788 D 4Fe-4S ferredoxin 1799495..1799788 Escherichia coli APEC O1 4492039 YP_852792.1 CDS ydiD NC_008563.1 1799791 1801491 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1799791..1801491 Escherichia coli APEC O1 4492040 YP_852793.1 CDS pps NC_008563.1 1801548 1803926 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1801548..1803926) Escherichia coli APEC O1 4492041 YP_852794.1 CDS APECO1_779 NC_008563.1 1804259 1805092 D hypothetical protein 1804259..1805092 Escherichia coli APEC O1 4492042 YP_852795.1 CDS aroH NC_008563.1 1805249 1806295 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1805249..1806295 Escherichia coli APEC O1 4492043 YP_852796.1 CDS ydiU NC_008563.1 1806622 1808058 R hypothetical protein complement(1806622..1808058) Escherichia coli APEC O1 4492044 YP_852797.1 CDS ydiV NC_008563.1 1808121 1808834 R hypothetical protein complement(1808121..1808834) Escherichia coli APEC O1 4492045 YP_852798.1 CDS nlpC NC_008563.1 1809081 1809545 R lipoprotein complement(1809081..1809545) Escherichia coli APEC O1 4492046 YP_852799.1 CDS btuC NC_008563.1 1809623 1810372 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1809623..1810372) Escherichia coli APEC O1 4492047 YP_852800.1 CDS btuE NC_008563.1 1810372 1810923 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(1810372..1810923) Escherichia coli APEC O1 4492048 YP_852801.1 CDS btuC NC_008563.1 1810985 1811965 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1810985..1811965) Escherichia coli APEC O1 4492049 YP_852802.1 CDS pheT NC_008563.1 1812370 1814757 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1812370..1814757) Escherichia coli APEC O1 4492050 YP_852803.2 CDS pheS NC_008563.1 1814772 1815755 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1814772..1815755) Escherichia coli APEC O1 4492051 YP_852804.1 CDS rplT NC_008563.1 1816206 1816562 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1816206..1816562) Escherichia coli APEC O1 4492052 YP_852806.1 CDS thrS NC_008563.1 1817455 1819383 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1817455..1819383) Escherichia coli APEC O1 4492054 YP_852807.1 CDS APECO1_792 NC_008563.1 1819906 1820340 D hypothetical protein 1819906..1820340 Escherichia coli APEC O1 4494428 YP_852808.1 CDS ydiY NC_008563.1 1821267 1822025 R hypothetical protein complement(1821267..1822025) Escherichia coli APEC O1 4494429 YP_852809.1 CDS pfkB NC_008563.1 1822308 1823240 D 6-phosphofructokinase 1822308..1823240 Escherichia coli APEC O1 4494430 YP_852810.1 CDS ydiZ NC_008563.1 1823341 1823631 D hypothetical protein 1823341..1823631 Escherichia coli APEC O1 4494431 YP_852811.1 CDS yniA NC_008563.1 1823737 1824597 D phosphotransferase/kinase 1823737..1824597 Escherichia coli APEC O1 4494432 YP_852812.1 CDS yniB NC_008563.1 1824638 1825174 R hypothetical protein complement(1824638..1825174) Escherichia coli APEC O1 4494433 YP_852813.1 CDS yniC NC_008563.1 1825321 1825989 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1825321..1825989 Escherichia coli APEC O1 4494434 YP_852814.1 CDS ydjM NC_008563.1 1826141 1826743 D hypothetical protein 1826141..1826743 Escherichia coli APEC O1 4494435 YP_852815.1 CDS ydjN NC_008563.1 1826876 1828267 D symporter protein YdjN 1826876..1828267 Escherichia coli APEC O1 4494436 YP_852816.1 CDS cedA NC_008563.1 1828314 1828577 R cell division modulator complement(1828314..1828577) Escherichia coli APEC O1 4494437 YP_852817.1 CDS katE NC_008563.1 1828760 1831021 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1828760..1831021 Escherichia coli APEC O1 4494438 YP_852818.1 CDS ydjC NC_008563.1 1831067 1831825 R hypothetical protein complement(1831067..1831825) Escherichia coli APEC O1 4494439 YP_852819.1 CDS celF NC_008563.1 1831838 1833190 R 6-phospho-beta-glucosidase complement(1831838..1833190) Escherichia coli APEC O1 4494440 YP_852820.1 CDS celD NC_008563.1 1833294 1834136 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1833294..1834136) Escherichia coli APEC O1 4494441 YP_852821.1 CDS celC NC_008563.1 1834144 1834494 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1834144..1834494) Escherichia coli APEC O1 4494442 YP_852822.1 CDS celB NC_008563.1 1834545 1835903 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1834545..1835903) Escherichia coli APEC O1 4494443 YP_852823.1 CDS celA NC_008563.1 1835988 1836308 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1835988..1836308) Escherichia coli APEC O1 4494444 YP_852824.1 CDS osmE NC_008563.1 1836607 1836945 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1836607..1836945) Escherichia coli APEC O1 4494445 YP_852825.1 CDS nadE NC_008563.1 1837147 1837974 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1837147..1837974 Escherichia coli APEC O1 4494446 YP_852826.1 CDS thrL NC_008563.1 1838204 1839091 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1838204..1839091 Escherichia coli APEC O1 4494447 YP_852827.1 CDS ydjR NC_008563.1 1839051 1839626 R hypothetical protein complement(1839051..1839626) Escherichia coli APEC O1 4495250 YP_852828.1 CDS spy NC_008563.1 1839829 1840314 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(1839829..1840314) Escherichia coli APEC O1 4495251 YP_852829.1 CDS ydjS NC_008563.1 1840644 1841612 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1840644..1841612) Escherichia coli APEC O1 4495252 YP_852830.1 CDS astB NC_008563.1 1841605 1842948 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1841605..1842948) Escherichia coli APEC O1 4495253 YP_852831.1 CDS thrL NC_008563.1 1842945 1844132 R succinylglutamic semialdehyde dehydrogenase complement(1842945..1844132) Escherichia coli APEC O1 4495254 YP_852832.1 CDS astA NC_008563.1 1844419 1845453 R arginine succinyltransferase complement(1844419..1845453) Escherichia coli APEC O1 4495255 YP_852833.1 CDS cstC NC_008563.1 1845450 1846670 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1845450..1846670) Escherichia coli APEC O1 4495256 YP_852834.1 CDS xthA NC_008563.1 1847104 1847922 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1847104..1847922 Escherichia coli APEC O1 4495257 YP_852835.1 CDS ydjX NC_008563.1 1848089 1848799 D hypothetical protein 1848089..1848799 Escherichia coli APEC O1 4495258 YP_852836.1 CDS ydjY NC_008563.1 1848642 1849481 D hypothetical protein 1848642..1849481 Escherichia coli APEC O1 4495259 YP_852837.1 CDS ydjZ NC_008563.1 1849495 1850202 D hypothetical protein 1849495..1850202 Escherichia coli APEC O1 4495260 YP_852838.1 CDS ynjA NC_008563.1 1850202 1850750 D hypothetical protein 1850202..1850750 Escherichia coli APEC O1 4495261 YP_852839.1 CDS ynjB NC_008563.1 1850760 1851926 D ABC transporter substrate-binding protein 1850760..1851926 Escherichia coli APEC O1 4495262 YP_852840.1 CDS ynjC NC_008563.1 1851899 1853434 D ABC transporter permease 1851899..1853434 Escherichia coli APEC O1 4495263 YP_852841.1 CDS ynjD NC_008563.1 1853347 1854087 D ABC transporter ATP-binding protein 1853347..1854087 Escherichia coli APEC O1 4495264 YP_852842.1 CDS ynjE NC_008563.1 1854139 1855461 D thiosulfate sulfurtransferase YnjE 1854139..1855461 Escherichia coli APEC O1 4495265 YP_852843.1 CDS ynjF NC_008563.1 1855470 1856096 R hypothetical protein complement(1855470..1856096) Escherichia coli APEC O1 4495266 YP_852844.1 CDS ynjG NC_008563.1 1856177 1856584 D pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1856177..1856584 Escherichia coli APEC O1 4495267 YP_852845.1 CDS ynjH NC_008563.1 1856550 1856822 R hypothetical protein complement(1856550..1856822) Escherichia coli APEC O1 4495268 YP_852846.1 CDS gdhA NC_008563.1 1857058 1858401 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1857058..1858401 Escherichia coli APEC O1 4491997 YP_852847.1 CDS topB NC_008563.1 1858478 1860487 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1858478..1860487) Escherichia coli APEC O1 4491998 YP_852848.1 CDS selD NC_008563.1 1860438 1861487 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1860438..1861487) Escherichia coli APEC O1 4491999 YP_852849.2 CDS ydjA NC_008563.1 1861598 1862149 R hypothetical protein complement(1861598..1862149) Escherichia coli APEC O1 4492000 YP_852850.1 CDS sppA NC_008563.1 1862310 1864166 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1862310..1864166 Escherichia coli APEC O1 4492001 YP_852851.1 CDS ansA NC_008563.1 1864333 1865349 D converts asparagine to aspartate and ammonia; asparaginase 1864333..1865349 Escherichia coli APEC O1 4492002 YP_852852.1 CDS ydjB NC_008563.1 1865342 1866001 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1865342..1866001 Escherichia coli APEC O1 4492003 YP_852853.1 CDS ydjE NC_008563.1 1866094 1867521 R metabolite transport protein complement(1866094..1867521) Escherichia coli APEC O1 4492004 YP_852854.1 CDS APECO1_839 NC_008563.1 1867570 1868328 R Z2808; DEOR-type transcriptional regulator complement(1867570..1868328) Escherichia coli APEC O1 4492005 YP_852855.1 CDS ydjG NC_008563.1 1868465 1869445 R oxidoreductase complement(1868465..1869445) Escherichia coli APEC O1 4492006 YP_852856.1 CDS ydjH NC_008563.1 1869455 1870222 R sugar kinase complement(1869455..1870222) Escherichia coli APEC O1 4492007 YP_852857.1 CDS ydjI NC_008563.1 1870406 1871242 R hypothetical protein complement(1870406..1871242) Escherichia coli APEC O1 4492008 YP_852858.1 CDS ydjJ NC_008563.1 1871263 1872306 R zinc-type alcohol dehydrogenase-like protein complement(1871263..1872306) Escherichia coli APEC O1 4492009 YP_852859.1 CDS ydjK NC_008563.1 1872323 1873702 R metabolite transport protein complement(1872323..1873702) Escherichia coli APEC O1 4492010 YP_852860.1 CDS ydjL NC_008563.1 1873729 1874805 R oxidoreductase complement(1873729..1874805) Escherichia coli APEC O1 4492011 YP_852861.1 CDS yeaA NC_008563.1 1875489 1875932 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1875489..1875932) Escherichia coli APEC O1 4492012 YP_852862.1 CDS gapA NC_008563.1 1876235 1877239 D glyceraldehyde 3-phosphate dehydrogenase A 1876235..1877239 Escherichia coli APEC O1 4492013 YP_852863.1 CDS yeaD NC_008563.1 1877302 1878207 D hypothetical protein 1877302..1878207 Escherichia coli APEC O1 4492014 YP_852864.1 CDS yeaE NC_008563.1 1878258 1879157 R hypothetical protein complement(1878258..1879157) Escherichia coli APEC O1 4492015 YP_852865.1 CDS yeaF NC_008563.1 1879202 1879948 R MltA-interacting protein complement(1879202..1879948) Escherichia coli APEC O1 4492016 YP_852866.1 CDS yeaG NC_008563.1 1880384 1882318 D hypothetical protein 1880384..1882318 Escherichia coli APEC O1 4495406 YP_852867.1 CDS yeaH NC_008563.1 1882431 1883714 D hypothetical protein 1882431..1883714 Escherichia coli APEC O1 4495407 YP_852868.1 CDS yeaI NC_008563.1 1883861 1885336 D hypothetical protein 1883861..1885336 Escherichia coli APEC O1 4495409 YP_852869.1 CDS yeaJ NC_008563.1 1885337 1887007 D hypothetical protein 1885337..1887007 Escherichia coli APEC O1 4495410 YP_852870.1 CDS yeaK NC_008563.1 1887050 1887553 D hypothetical protein 1887050..1887553 Escherichia coli APEC O1 4495411 YP_852871.1 CDS yeaM NC_008563.1 1888231 1889052 R transcriptional regulator complement(1888231..1889052) Escherichia coli APEC O1 4495412 YP_852872.1 CDS yeaN NC_008563.1 1889149 1890330 D transporter 1889149..1890330 Escherichia coli APEC O1 4495413 YP_852873.2 CDS yeaO NC_008563.1 1890385 1890732 D hypothetical protein 1890385..1890732 Escherichia coli APEC O1 4495414 YP_852874.1 CDS yeaP NC_008563.1 1891191 1892216 D hypothetical protein 1891191..1892216 Escherichia coli APEC O1 4495415 YP_852875.1 CDS yeaR NC_008563.1 1892897 1893388 D hypothetical protein 1892897..1893388 Escherichia coli APEC O1 4495416 YP_852876.1 CDS yeaS NC_008563.1 1893597 1894235 R leucine export protein LeuE complement(1893597..1894235) Escherichia coli APEC O1 4495417 YP_852877.1 CDS rnd NC_008563.1 1894778 1895893 R ribonuclease D complement(1894778..1895893) Escherichia coli APEC O1 4495418 YP_852878.1 CDS fadD NC_008563.1 1895975 1897726 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1895975..1897726) Escherichia coli APEC O1 4495419 YP_852879.1 CDS yeaY NC_008563.1 1897865 1898446 R lipoprotein complement(1897865..1898446) Escherichia coli APEC O1 4495420 YP_852880.1 CDS yeaZ NC_008563.1 1898486 1899181 R O-sialoglycoprotein endopeptidase complement(1898486..1899181) Escherichia coli APEC O1 4495421 YP_852881.1 CDS yoaA NC_008563.1 1899239 1901149 R ATP-dependent helicase complement(1899239..1901149) Escherichia coli APEC O1 4495422 YP_852882.1 CDS yoaB NC_008563.1 1901233 1901625 D hypothetical protein 1901233..1901625 Escherichia coli APEC O1 4495423 YP_852883.1 CDS yoaC NC_008563.1 1901987 1902346 D hypothetical protein 1901987..1902346 Escherichia coli APEC O1 4495424 YP_852884.1 CDS pabB NC_008563.1 1902719 1904080 D para-aminobenzoate synthase component I 1902719..1904080 Escherichia coli APEC O1 4493888 YP_852885.1 CDS yeaB NC_008563.1 1904084 1904662 D hypothetical protein 1904084..1904662 Escherichia coli APEC O1 4493889 YP_852886.1 CDS sdaA NC_008563.1 1904846 1906210 D L-serine dehydratase 1 1904846..1906210 Escherichia coli APEC O1 4493890 YP_852887.1 CDS yoaD NC_008563.1 1906332 1907939 D hypothetical protein 1906332..1907939 Escherichia coli APEC O1 4493891 YP_852888.1 CDS yoaE NC_008563.1 1907943 1909499 R hypothetical protein complement(1907943..1909499) Escherichia coli APEC O1 4493892 YP_852889.1 CDS manX NC_008563.1 1909962 1910933 D PTS system mannose-specific transporter subunit IIAB 1909962..1910933 Escherichia coli APEC O1 4493893 YP_852890.1 CDS manY NC_008563.1 1910996 1911796 D mannose-specific enzyme IIC 1910996..1911796 Escherichia coli APEC O1 4493894 YP_852891.1 CDS manZ NC_008563.1 1911800 1912660 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1911800..1912660 Escherichia coli APEC O1 4493895 YP_852892.1 CDS yobD NC_008563.1 1912715 1913173 D hypothetical protein 1912715..1913173 Escherichia coli APEC O1 4493896 YP_852893.1 CDS yebN NC_008563.1 1913548 1914168 D membrane protein YebN; hypothetical protein 1913548..1914168 Escherichia coli APEC O1 4493897 YP_852894.1 CDS rrmA NC_008563.1 1914165 1914974 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A complement(1914165..1914974) Escherichia coli APEC O1 4493898 YP_852895.1 CDS APECO1_880 NC_008563.1 1915467 1915730 D hypothetical protein 1915467..1915730 Escherichia coli APEC O1 4493899 YP_852896.1 CDS yebO NC_008563.1 1916176 1916463 R hypothetical protein complement(1916176..1916463) Escherichia coli APEC O1 4493900 YP_852897.1 CDS kdgR NC_008563.1 1917223 1918014 R transcriptional regulator complement(1917223..1918014) Escherichia coli APEC O1 4493901 YP_852898.1 CDS yebQ NC_008563.1 1918080 1919564 D transporter 1918080..1919564 Escherichia coli APEC O1 4493902 YP_852899.1 CDS htpX NC_008563.1 1919610 1920491 R metalloprotease; heat shock protein HtpX complement(1919610..1920491) Escherichia coli APEC O1 4493903 YP_852900.1 CDS prc NC_008563.1 1920683 1922731 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1920683..1922731) Escherichia coli APEC O1 4493904 YP_852901.1 CDS proQ NC_008563.1 1922751 1923449 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(1922751..1923449) Escherichia coli APEC O1 4493905 YP_852902.1 CDS yebS NC_008563.1 1924173 1925456 D hypothetical protein 1924173..1925456 Escherichia coli APEC O1 4493906 YP_852903.1 CDS yebT NC_008563.1 1925419 1928058 D hypothetical protein 1925419..1928058 Escherichia coli APEC O1 4493907 YP_852904.1 CDS yebU NC_008563.1 1928132 1929577 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1928132..1929577 Escherichia coli APEC O1 4491921 YP_852905.1 CDS yebW NC_008563.1 1929952 1930227 D hypothetical protein 1929952..1930227 Escherichia coli APEC O1 4491922 YP_852906.1 CDS pphA NC_008563.1 1930228 1930884 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(1930228..1930884) Escherichia coli APEC O1 4491923 YP_852907.1 CDS yebY NC_008563.1 1931279 1931620 R hypothetical protein complement(1931279..1931620) Escherichia coli APEC O1 4491924 YP_852908.1 CDS yebZ NC_008563.1 1931633 1932505 R hypothetical protein complement(1931633..1932505) Escherichia coli APEC O1 4491925 YP_852909.1 CDS yobB NC_008563.1 1933585 1934010 D hypothetical protein 1933585..1934010 Escherichia coli APEC O1 4491926 YP_852910.1 CDS exoX NC_008563.1 1934033 1934695 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1934033..1934695 Escherichia coli APEC O1 4491927 YP_852911.1 CDS ptrB NC_008563.1 1934692 1936752 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(1934692..1936752) Escherichia coli APEC O1 4491928 YP_852912.1 CDS yebE NC_008563.1 1936961 1937620 R hypothetical protein complement(1936961..1937620) Escherichia coli APEC O1 4491929 YP_852913.1 CDS yebF NC_008563.1 1937947 1938315 R secreted protein; unknown function; hypothetical protein complement(1937947..1938315) Escherichia coli APEC O1 4491930 YP_852914.1 CDS purT NC_008563.1 1938794 1939972 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1938794..1939972 Escherichia coli APEC O1 4491931 YP_852915.1 CDS eda NC_008563.1 1940028 1940669 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1940028..1940669) Escherichia coli APEC O1 4491932 YP_852916.1 CDS edd NC_008563.1 1940706 1942583 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1940706..1942583) Escherichia coli APEC O1 4491933 YP_852917.1 CDS zwf NC_008563.1 1942752 1944227 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1942752..1944227) Escherichia coli APEC O1 4491934 YP_852918.1 CDS yebK NC_008563.1 1944565 1945434 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1944565..1945434 Escherichia coli APEC O1 4491935 YP_852919.1 CDS pykA NC_008563.1 1945421 1947004 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1945421..1947004 Escherichia coli APEC O1 4491936 YP_852920.1 CDS msbB NC_008563.1 1947136 1948107 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(1947136..1948107) Escherichia coli APEC O1 4491937 YP_852921.1 CDS APECO1_906 NC_008563.1 1948226 1949548 R hypothetical protein complement(1948226..1949548) Escherichia coli APEC O1 4491938 YP_852922.1 CDS znuA NC_008563.1 1949564 1950550 R yebL precursor; involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(1949564..1950550) Escherichia coli APEC O1 4491939 YP_852923.1 CDS znuC NC_008563.1 1950575 1951330 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1950575..1951330 Escherichia coli APEC O1 4491478 YP_852924.1 CDS znuB NC_008563.1 1951327 1952112 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1951327..1952112 Escherichia coli APEC O1 4491479 YP_852925.1 CDS ruvB NC_008563.1 1952329 1953339 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1952329..1953339) Escherichia coli APEC O1 4491480 YP_852926.1 CDS ruvA NC_008563.1 1953348 1953959 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1953348..1953959) Escherichia coli APEC O1 4491481 YP_852927.1 CDS yebB NC_008563.1 1954236 1954838 D hypothetical protein 1954236..1954838 Escherichia coli APEC O1 4491482 YP_852928.1 CDS ruvC NC_008563.1 1954840 1955364 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1954840..1955364) Escherichia coli APEC O1 4491483 YP_852929.1 CDS yebC NC_008563.1 1955396 1956136 R hypothetical protein complement(1955396..1956136) Escherichia coli APEC O1 4491484 YP_852930.1 CDS ntpA NC_008563.1 1956165 1956608 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(1956165..1956608) Escherichia coli APEC O1 4491485 YP_852931.1 CDS aspS NC_008563.1 1956610 1958382 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1956610..1958382) Escherichia coli APEC O1 4491486 YP_852932.1 CDS yecD NC_008563.1 1958692 1959258 D hypothetical protein 1958692..1959258 Escherichia coli APEC O1 4491487 YP_852933.1 CDS yecE NC_008563.1 1959255 1960073 D hypothetical protein 1959255..1960073 Escherichia coli APEC O1 4491488 YP_852934.1 CDS yecN NC_008563.1 1960096 1960521 D hypothetical protein 1960096..1960521 Escherichia coli APEC O1 4491489 YP_852935.1 CDS yecO NC_008563.1 1960562 1961305 D hypothetical protein 1960562..1961305 Escherichia coli APEC O1 4491490 YP_852936.1 CDS yecP NC_008563.1 1961302 1962273 D hypothetical protein 1961302..1962273 Escherichia coli APEC O1 4491491 YP_852937.1 CDS bisZ NC_008563.1 1962438 1964780 R trimethylamine-N-oxide reductase 2 complement(1962438..1964780) Escherichia coli APEC O1 4491495 YP_852938.1 CDS torY NC_008563.1 1964891 1965991 R TMAO reductase III (TorYZ), cytochrome c-type subunit complement(1964891..1965991) Escherichia coli APEC O1 4491496 YP_852939.1 CDS cutC NC_008563.1 1966379 1967125 R copper homeostasis protein CutC complement(1966379..1967125) Escherichia coli APEC O1 4491497 YP_852940.1 CDS yecM NC_008563.1 1967139 1967711 R hypothetical protein complement(1967139..1967711) Escherichia coli APEC O1 4495750 YP_852941.1 CDS argS NC_008563.1 1967921 1969654 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1967921..1969654 Escherichia coli APEC O1 4495751 YP_852942.1 CDS flhE NC_008563.1 1969707 1970099 R flagellar protein FlhE complement(1969707..1970099) Escherichia coli APEC O1 4495752 YP_852943.2 CDS flhA NC_008563.1 1970099 1972177 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(1970099..1972177) Escherichia coli APEC O1 4495753 YP_852944.1 CDS flhB NC_008563.1 1972170 1973318 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(1972170..1973318) Escherichia coli APEC O1 4495754 YP_852945.1 CDS cheZ NC_008563.1 1973527 1974171 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(1973527..1974171) Escherichia coli APEC O1 4495755 YP_852946.1 CDS cheY NC_008563.1 1974182 1974571 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(1974182..1974571) Escherichia coli APEC O1 4495756 YP_852947.1 CDS cheB NC_008563.1 1974586 1975635 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(1974586..1975635) Escherichia coli APEC O1 4495757 YP_852948.1 CDS cheR NC_008563.1 1975638 1976498 R methylates the MCP; chemotaxis methyltransferase CheR complement(1975638..1976498) Escherichia coli APEC O1 4495758 YP_852949.1 CDS tar NC_008563.1 1976789 1978450 R methyl-accepting chemotaxis protein II complement(1976789..1978450) Escherichia coli APEC O1 4495759 YP_852950.1 CDS cheW NC_008563.1 1978595 1979098 R purine-binding chemotaxis protein complement(1978595..1979098) Escherichia coli APEC O1 4495760 YP_852951.1 CDS cheA NC_008563.1 1979119 1981122 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(1979119..1981122) Escherichia coli APEC O1 4495761 YP_852952.1 CDS motB NC_008563.1 1981088 1982014 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(1981088..1982014) Escherichia coli APEC O1 4495762 YP_852953.1 CDS motA NC_008563.1 1982011 1982898 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(1982011..1982898) Escherichia coli APEC O1 4495763 YP_852954.1 CDS flhC NC_008563.1 1983025 1983603 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(1983025..1983603) Escherichia coli APEC O1 4495764 YP_852955.1 CDS flhD NC_008563.1 1983606 1983965 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(1983606..1983965) Escherichia coli APEC O1 4495765 YP_852956.1 CDS yecG NC_008563.1 1984736 1985164 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1984736..1985164 Escherichia coli APEC O1 4495766 YP_852957.1 CDS otsA NC_008563.1 1985171 1986604 R trehalose-6-phosphate synthase complement(1985171..1986604) Escherichia coli APEC O1 4495767 YP_852958.1 CDS otsB NC_008563.1 1986570 1987427 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(1986570..1987427) Escherichia coli APEC O1 4495768 YP_852959.1 CDS araH NC_008563.1 1987537 1988526 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(1987537..1988526) Escherichia coli APEC O1 4494623 YP_852960.1 CDS araG NC_008563.1 1988538 1990097 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(1988538..1990097) Escherichia coli APEC O1 4494624 YP_852961.1 CDS araF NC_008563.1 1990122 1991162 R L-arabinose-binding periplasmic protein complement(1990122..1991162) Escherichia coli APEC O1 4494625 YP_852962.1 CDS yecI NC_008563.1 1991908 1992411 D ferritin-like protein 1991908..1992411 Escherichia coli APEC O1 4494626 YP_852964.1 CDS yecR NC_008563.1 1993205 1993528 D hypothetical protein 1993205..1993528 Escherichia coli APEC O1 4494628 YP_852965.1 CDS ftn NC_008563.1 1993700 1994197 D cytoplasmic iron storage protein; ferritin 1993700..1994197 Escherichia coli APEC O1 4494629 YP_852966.1 CDS tyrP NC_008563.1 1994665 1995876 D tyrosine-specific transporter 1994665..1995876 Escherichia coli APEC O1 4494630 YP_852967.1 CDS APECO1_953 NC_008563.1 1995927 1996592 R hypothetical protein complement(1995927..1996592) Escherichia coli APEC O1 4494631 YP_852968.1 CDS pgsA NC_008563.1 1997242 1997790 R CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyl transferase; phosphatidylglycerophosphate synthetase complement(1997242..1997790) Escherichia coli APEC O1 4494632 YP_852969.1 CDS uvrC NC_008563.1 1997847 1999679 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1997847..1999679) Escherichia coli APEC O1 4494633 YP_852970.1 CDS uvrY NC_008563.1 1999676 2000296 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(1999676..2000296) Escherichia coli APEC O1 4494634 YP_852971.1 CDS sdiA NC_008563.1 2001083 2001805 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2001083..2001805) Escherichia coli APEC O1 4494635 YP_852972.1 CDS yecC NC_008563.1 2002035 2002787 R amino acid ABC transporter ATP-binding protein complement(2002035..2002787) Escherichia coli APEC O1 4494636 YP_852973.1 CDS yecS NC_008563.1 2002784 2003452 R transport system permease complement(2002784..2003452) Escherichia coli APEC O1 4494637 YP_852974.1 CDS yedO NC_008563.1 2003467 2004549 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2003467..2004549) Escherichia coli APEC O1 4494638 YP_852975.1 CDS fliY NC_008563.1 2004558 2005415 R cystine transporter subunit complement(2004558..2005415) Escherichia coli APEC O1 4494639 YP_852976.1 CDS fliZ NC_008563.1 2005446 2006033 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2005446..2006033) Escherichia coli APEC O1 4494640 YP_852977.1 CDS fliA NC_008563.1 2006043 2006762 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2006043..2006762) Escherichia coli APEC O1 4494641 YP_852978.1 CDS fliC NC_008563.1 2007082 2008839 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2007082..2008839) Escherichia coli APEC O1 4494642 YP_852979.1 CDS fliD NC_008563.1 2009105 2010511 D involved in flagellin assembly; flagellar capping protein 2009105..2010511 Escherichia coli APEC O1 4491850 YP_852980.1 CDS fliS NC_008563.1 2010536 2010946 D flagellin specific chaperone; flagellar protein FliS 2010536..2010946 Escherichia coli APEC O1 4491851 YP_852981.1 CDS fliT NC_008563.1 2010946 2011311 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2010946..2011311 Escherichia coli APEC O1 4491852 YP_852982.1 CDS amyA NC_008563.1 2011389 2012876 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2011389..2012876 Escherichia coli APEC O1 4491853 YP_852983.1 CDS yedD NC_008563.1 2012910 2013326 R hypothetical protein complement(2012910..2013326) Escherichia coli APEC O1 4491854 YP_852984.1 CDS yedE NC_008563.1 2013510 2014715 D hypothetical protein 2013510..2014715 Escherichia coli APEC O1 4491855 YP_852985.1 CDS yedK NC_008563.1 2014961 2015722 D hypothetical protein 2014961..2015722 Escherichia coli APEC O1 4491856 YP_852986.1 CDS nmpC NC_008563.1 2016235 2017317 D outer membrane porin protein NmpC 2016235..2017317 Escherichia coli APEC O1 4491857 YP_852987.1 CDS ybcM NC_008563.1 2017819 2018616 R transcriptional regulator complement(2017819..2018616) Escherichia coli APEC O1 4491858 YP_852988.1 CDS ybcL NC_008563.1 2018626 2019177 R DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor complement(2018626..2019177) Escherichia coli APEC O1 4491859 YP_852989.1 CDS emrE NC_008563.1 2019346 2019843 R member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein complement(2019346..2019843) Escherichia coli APEC O1 4491860 YP_852990.1 CDS fliE NC_008563.1 2020023 2020337 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2020023..2020337) Escherichia coli APEC O1 4491861 YP_852991.1 CDS fliF NC_008563.1 2020552 2021553 D flagellar M-ring protein 2020552..2021553 Escherichia coli APEC O1 4491862 YP_852992.1 CDS fliG NC_008563.1 2022204 2023199 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2022204..2023199 Escherichia coli APEC O1 4491863 YP_852993.1 CDS fliH NC_008563.1 2023192 2023878 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2023192..2023878 Escherichia coli APEC O1 4491864 YP_852994.1 CDS fliI NC_008563.1 2023878 2025251 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2023878..2025251 Escherichia coli APEC O1 4491865 YP_852995.1 CDS fliJ NC_008563.1 2025270 2025713 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2025270..2025713 Escherichia coli APEC O1 4491866 YP_852996.1 CDS fliK NC_008563.1 2025710 2026837 D flagellar hook-length control protein 2025710..2026837 Escherichia coli APEC O1 4491867 YP_852997.1 CDS fliL NC_008563.1 2026942 2027406 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2026942..2027406 Escherichia coli APEC O1 4491868 YP_852998.1 CDS fliM NC_008563.1 2027366 2028415 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2027366..2028415 Escherichia coli APEC O1 4492055 YP_852999.1 CDS fliN NC_008563.1 2028412 2028825 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2028412..2028825 Escherichia coli APEC O1 4492056 YP_853000.1 CDS fliO NC_008563.1 2028825 2029193 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2028825..2029193 Escherichia coli APEC O1 4492057 YP_853001.1 CDS fliP NC_008563.1 2029193 2029930 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2029193..2029930 Escherichia coli APEC O1 4492058 YP_853002.1 CDS fliQ NC_008563.1 2029940 2030209 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2029940..2030209 Escherichia coli APEC O1 4492059 YP_853003.1 CDS fliR NC_008563.1 2030218 2031003 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2030218..2031003 Escherichia coli APEC O1 4492060 YP_853004.1 CDS rcsA NC_008563.1 2031293 2031916 D positive regulator for ctr capsule biosynthesis, positive transcription factor 2031293..2031916 Escherichia coli APEC O1 4492061 YP_853005.1 CDS APECO1_991 NC_008563.1 2031993 2032268 D hypothetical protein 2031993..2032268 Escherichia coli APEC O1 4492062 YP_853007.1 CDS yedP NC_008563.1 2032836 2033651 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2032836..2033651 Escherichia coli APEC O1 4492064 YP_853008.1 CDS yedQ NC_008563.1 2033648 2035342 R hypothetical protein complement(2033648..2035342) Escherichia coli APEC O1 4492065 YP_853009.1 CDS yedI NC_008563.1 2035774 2036691 R hypothetical protein complement(2035774..2036691) Escherichia coli APEC O1 4492639 YP_853010.1 CDS yedA NC_008563.1 2036864 2037784 D hypothetical protein 2036864..2037784 Escherichia coli APEC O1 4492640 YP_853011.1 CDS vsr NC_008563.1 2037773 2038243 R DNA mismatch endonuclease, patch repair protein complement(2037773..2038243) Escherichia coli APEC O1 4492641 YP_853012.1 CDS dcm NC_008563.1 2038224 2039642 R DNA cytosine methylase complement(2038224..2039642) Escherichia coli APEC O1 4492642 YP_853013.1 CDS yedJ NC_008563.1 2039709 2040404 R hypothetical protein complement(2039709..2040404) Escherichia coli APEC O1 4492643 YP_853014.1 CDS yedR NC_008563.1 2040444 2040809 R Outer membrane protein N precursor complement(2040444..2040809) Escherichia coli APEC O1 4492644 YP_853015.1 CDS ompN NC_008563.1 2041345 2042490 D Outer membrane protein N precursor 2041345..2042490 Escherichia coli APEC O1 4492645 YP_853016.1 CDS hchA NC_008563.1 2043085 2043936 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2043085..2043936 Escherichia coli APEC O1 4492646 YP_853017.1 CDS yedV NC_008563.1 2044043 2045401 R 2-component sensor protein complement(2044043..2045401) Escherichia coli APEC O1 4492647 YP_853018.1 CDS yedW NC_008563.1 2045401 2046183 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2045401..2046183) Escherichia coli APEC O1 4492648 YP_853019.1 CDS yedX NC_008563.1 2046205 2046618 D hypothetical protein 2046205..2046618 Escherichia coli APEC O1 4492649 YP_853020.1 CDS yedY NC_008563.1 2046727 2047731 D reductase; in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2046727..2047731 Escherichia coli APEC O1 4492650 YP_853021.1 CDS yedZ NC_008563.1 2047732 2048367 D conserved inner membrane protein; in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2047732..2048367 Escherichia coli APEC O1 4492651 YP_853022.1 CDS yodA NC_008563.1 2048927 2049274 D conserved metal-binding protein; YodA protein 2048927..2049274 Escherichia coli APEC O1 4492652 YP_853023.1 CDS APECO1_1009 NC_008563.1 2049310 2049639 D hypothetical protein 2049310..2049639 Escherichia coli APEC O1 4492653 YP_853024.1 CDS APECO1_1010 NC_008563.1 2050863 2051642 D hypothetical protein 2050863..2051642 Escherichia coli APEC O1 4492654 YP_853025.1 CDS APECO1_1011 NC_008563.1 2051722 2052057 D hypothetical protein 2051722..2052057 Escherichia coli APEC O1 4492655 YP_853026.1 CDS APECO1_1012 NC_008563.1 2052150 2052428 R hypothetical protein complement(2052150..2052428) Escherichia coli APEC O1 4492656 YP_853027.1 CDS APECO1_6001 NC_008563.1 2052425 2054491 R hypothetical protein complement(2052425..2054491) Escherichia coli APEC O1 4492657 YP_853028.1 CDS APECO1_6002 NC_008563.1 2054544 2058026 R tail component of prophage complement(2054544..2058026) Escherichia coli APEC O1 4493946 YP_853029.1 CDS APECO1_6003 NC_008563.1 2058087 2058758 R tail assembly protein I complement(2058087..2058758) Escherichia coli APEC O1 4493947 YP_853030.1 CDS APECO1_6004 NC_008563.1 2058656 2059399 R tail assembly protein complement(2058656..2059399) Escherichia coli APEC O1 4493948 YP_853031.1 CDS APECO1_6005 NC_008563.1 2059398 2060108 D hypothetical protein 2059398..2060108 Escherichia coli APEC O1 4493949 YP_853032.1 CDS APECO1_6006 NC_008563.1 2060102 2060443 R phage-related; minor tail protein complement(2060102..2060443) Escherichia coli APEC O1 4493950 YP_853033.1 CDS APECO1_6007 NC_008563.1 2060436 2063681 R phage-related minor tail protein complement(2060436..2063681) Escherichia coli APEC O1 4493951 YP_853034.1 CDS APECO1_1015 NC_008563.1 2063722 2064012 R Gp14; phage-related minor tail protein complement(2063722..2064012) Escherichia coli APEC O1 4493952 YP_853035.1 CDS APECO1_1016 NC_008563.1 2064024 2064410 R tail assembly chaperone complement(2064024..2064410) Escherichia coli APEC O1 4493953 YP_853036.1 CDS gp14 NC_008563.1 2064410 2065165 R phage major tail subunit complement(2064410..2065165) Escherichia coli APEC O1 4493954 YP_853037.1 CDS APECO1_1018 NC_008563.1 2065174 2065518 R Gp11; hypothetical protein complement(2065174..2065518) Escherichia coli APEC O1 4493955 YP_853038.1 CDS APECO1_1019 NC_008563.1 2065515 2065964 R Gp10; hypothetical protein complement(2065515..2065964) Escherichia coli APEC O1 4493956 YP_853039.1 CDS gp7 NC_008563.1 2065961 2066299 R head-tail adaptor complement(2065961..2066299) Escherichia coli APEC O1 4493957 YP_853040.1 CDS APECO1_1021 NC_008563.1 2066308 2066796 R hypothetical protein complement(2066308..2066796) Escherichia coli APEC O1 4493958 YP_853041.1 CDS APECO1_1022 NC_008563.1 2066702 2067919 R phage capsid protein complement(2066702..2067919) Escherichia coli APEC O1 4493959 YP_853042.1 CDS APECO1_1023 NC_008563.1 2067934 2068533 R phage capsid protease complement(2067934..2068533) Escherichia coli APEC O1 4493960 YP_853043.1 CDS APECO1_1024 NC_008563.1 2068526 2069752 R phage portal protein complement(2068526..2069752) Escherichia coli APEC O1 4493961 YP_853044.1 CDS APECO1_1025 NC_008563.1 2069900 2071657 R phage terminase complement(2069900..2071657) Escherichia coli APEC O1 4493962 YP_853045.1 CDS APECO1_1026 NC_008563.1 2071657 2072139 R phage terminase complement(2071657..2072139) Escherichia coli APEC O1 4493963 YP_853046.1 CDS hnhC NC_008563.1 2072287 2072637 R restriction endonuclase; HnhC complement(2072287..2072637) Escherichia coli APEC O1 4493964 YP_853047.1 CDS APECO1_1028 NC_008563.1 2072680 2073147 R endopeptidase complement(2072680..2073147) Escherichia coli APEC O1 4493965 YP_853048.1 CDS APECO1_1029 NC_008563.1 2073144 2073677 R phage lysozyme complement(2073144..2073677) Escherichia coli APEC O1 4493264 YP_853049.1 CDS ydfR NC_008563.1 2073741 2074091 R hypothetical protein complement(2073741..2074091) Escherichia coli APEC O1 4493265 YP_853050.1 CDS APECO1_1031 NC_008563.1 2075039 2075752 R hypothetical protein complement(2075039..2075752) Escherichia coli APEC O1 4493266 YP_853051.1 CDS APECO1_1032 NC_008563.1 2075982 2076677 R Q antiterminator encoded by prophage CP-933P complement(2075982..2076677) Escherichia coli APEC O1 4493267 YP_853052.1 CDS APECO1_1033 NC_008563.1 2076668 2077033 R Holliday junction resolvase complement(2076668..2077033) Escherichia coli APEC O1 4493268 YP_853053.1 CDS APECO1_1034 NC_008563.1 2077034 2078089 R hypothetical protein complement(2077034..2078089) Escherichia coli APEC O1 4493269 YP_853054.1 CDS APECO1_1035 NC_008563.1 2079275 2079790 R hypothetical protein complement(2079275..2079790) Escherichia coli APEC O1 4493270 YP_853055.1 CDS APECO1_1036 NC_008563.1 2080232 2080621 R hypothetical protein complement(2080232..2080621) Escherichia coli APEC O1 4493271 YP_853056.1 CDS APECO1_1037 NC_008563.1 2080590 2080901 R hypothetical protein complement(2080590..2080901) Escherichia coli APEC O1 4493272 YP_853057.1 CDS APECO1_1038 NC_008563.1 2080917 2081324 R hypothetical protein complement(2080917..2081324) Escherichia coli APEC O1 4493273 YP_853058.1 CDS APECO1_1040 NC_008563.1 2081365 2082441 R hypothetical protein complement(2081365..2082441) Escherichia coli APEC O1 4493274 YP_853059.1 CDS APECO1_1041 NC_008563.1 2082507 2082932 R hypothetical protein complement(2082507..2082932) Escherichia coli APEC O1 4493275 YP_853060.1 CDS APECO1_1042 NC_008563.1 2082929 2083255 R regulatory protein complement(2082929..2083255) Escherichia coli APEC O1 4493276 YP_853061.1 CDS APECO1_1043 NC_008563.1 2083263 2083682 D transcriptional regulator 2083263..2083682 Escherichia coli APEC O1 4493277 YP_853062.1 CDS APECO1_1044 NC_008563.1 2083983 2084339 D hypothetical protein 2083983..2084339 Escherichia coli APEC O1 4493278 YP_853063.1 CDS APECO1_1045 NC_008563.1 2084633 2084926 R hypothetical protein complement(2084633..2084926) Escherichia coli APEC O1 4493279 YP_853064.1 CDS APECO1_1046 NC_008563.1 2085001 2085333 R hypothetical protein complement(2085001..2085333) Escherichia coli APEC O1 4493280 YP_853065.1 CDS APECO1_1047 NC_008563.1 2085328 2085585 D hypothetical protein 2085328..2085585 Escherichia coli APEC O1 4493281 YP_853066.1 CDS APECO1_1048 NC_008563.1 2085665 2088136 D hypothetical protein 2085665..2088136 Escherichia coli APEC O1 4493282 YP_853067.1 CDS APECO1_1049 NC_008563.1 2088398 2089423 D phage integrase 2088398..2089423 Escherichia coli APEC O1 4492528 YP_853068.1 CDS APECO1_1050 NC_008563.1 2089620 2090456 D hypothetical protein 2089620..2090456 Escherichia coli APEC O1 4492529 YP_853069.1 CDS APECO1_1051 NC_008563.1 2091013 2091975 D phage integrase 2091013..2091975 Escherichia coli APEC O1 4492530 YP_853070.1 CDS APECO1_1052 NC_008563.1 2092250 2093554 R catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 complement(2092250..2093554) Escherichia coli APEC O1 4492531 YP_853071.1 CDS ybtX NC_008563.1 2093582 2094970 R hypothetical protein complement(2093582..2094970) Escherichia coli APEC O1 4492532 YP_853072.1 CDS APECO1_1055 NC_008563.1 2094855 2096684 R ABC transporter complement(2094855..2096684) Escherichia coli APEC O1 4492533 YP_853073.1 CDS ybtP NC_008563.1 2096644 2098446 R inner membrane ABC-transporter complement(2096644..2098446) Escherichia coli APEC O1 4492534 YP_853074.1 CDS APECO1_1057 NC_008563.1 2098613 2099572 D AraC family transcriptional regulator 2098613..2099572 Escherichia coli APEC O1 4492535 YP_853075.1 CDS irp2 NC_008563.1 2099745 2105870 D yersiniabactin biosynthetic protein 2099745..2105870 Escherichia coli APEC O1 4492536 YP_853076.1 CDS irp1 NC_008563.1 2105958 2115119 D yersiniabactin biosynthetic protein 2105958..2115119 Escherichia coli APEC O1 4492537 YP_853077.1 CDS ybtU NC_008563.1 2115444 2116544 D yersiniabactin biosynthetic protein 2115444..2116544 Escherichia coli APEC O1 4492538 YP_853078.1 CDS ybtT NC_008563.1 2116541 2117344 D yersiniabactin biosynthetic protein YbtT 2116541..2117344 Escherichia coli APEC O1 4492539 YP_853079.1 CDS ybtE NC_008563.1 2117348 2118925 D yersiniabactin siderophore biosynthetic protein 2117348..2118925 Escherichia coli APEC O1 4492540 YP_853080.1 CDS fyuA NC_008563.1 2119056 2121077 D pesticin/yersiniabactin receptor protein 2119056..2121077 Escherichia coli APEC O1 4492541 YP_853081.1 CDS APECO1_1064 NC_008563.1 2121671 2122477 D hypothetical protein 2121671..2122477 Escherichia coli APEC O1 4492542 YP_853082.1 CDS APECO1_1065 NC_008563.1 2122610 2124568 D autotransporter 2122610..2124568 Escherichia coli APEC O1 4492543 YP_853083.1 CDS APECO1_1066 NC_008563.1 2124696 2125748 R hypothetical protein complement(2124696..2125748) Escherichia coli APEC O1 4492544 YP_853084.1 CDS APECO1_1067 NC_008563.1 2126063 2127379 D shikimate transporter 2126063..2127379 Escherichia coli APEC O1 4492545 YP_853085.1 CDS amn NC_008563.1 2127433 2128935 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2127433..2128935 Escherichia coli APEC O1 4492546 YP_853086.1 CDS APECO1_1069 NC_008563.1 2129278 2129994 D hypothetical protein 2129278..2129994 Escherichia coli APEC O1 4492547 YP_853087.1 CDS APECO1_1070 NC_008563.1 2130050 2130337 R hypothetical protein complement(2130050..2130337) Escherichia coli APEC O1 4492548 YP_853088.1 CDS yeeO NC_008563.1 2130624 2132114 R hypothetical protein complement(2130624..2132114) Escherichia coli APEC O1 4492549 YP_853089.1 CDS cbl NC_008563.1 2132388 2133338 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2132388..2133338) Escherichia coli APEC O1 4492550 YP_853090.1 CDS nac NC_008563.1 2133440 2134357 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2133440..2134357) Escherichia coli APEC O1 4492551 YP_853091.1 CDS erfK NC_008563.1 2134815 2135750 R hypothetical protein complement(2134815..2135750) Escherichia coli APEC O1 4492552 YP_853092.1 CDS cobT NC_008563.1 2135812 2136891 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2135812..2136891) Escherichia coli APEC O1 4492553 YP_853093.1 CDS cobS NC_008563.1 2136903 2137682 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2136903..2137682) Escherichia coli APEC O1 4492554 YP_853094.1 CDS cobU NC_008563.1 2137643 2138188 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase complement(2137643..2138188) Escherichia coli APEC O1 4492555 YP_853095.1 CDS APECO1_1075 NC_008563.1 2140861 2141175 R hypothetical protein complement(2140861..2141175) Escherichia coli APEC O1 4492556 YP_853096.1 CDS APECO1_1076 NC_008563.1 2141294 2142508 D carbohydrate kinase 2141294..2142508 Escherichia coli APEC O1 4492557 YP_853097.1 CDS APECO1_1077 NC_008563.1 2142522 2143280 D hypothetical protein 2142522..2143280 Escherichia coli APEC O1 4492558 YP_853098.1 CDS APECO1_1078 NC_008563.1 2143337 2144302 D hypothetical protein 2143337..2144302 Escherichia coli APEC O1 4492559 YP_853099.1 CDS APECO1_1079 NC_008563.1 2144305 2145339 D phosphotriesterase-related protein 2144305..2145339 Escherichia coli APEC O1 4492560 YP_853100.1 CDS APECO1_1080 NC_008563.1 2145991 2146974 R transposase complement(2145991..2146974) Escherichia coli APEC O1 4492561 YP_853101.1 CDS APECO1_1081 NC_008563.1 2147032 2147370 R hypothetical protein complement(2147032..2147370) Escherichia coli APEC O1 4492776 YP_853102.1 CDS APECO1_1082 NC_008563.1 2147654 2148148 R hypothetical protein complement(2147654..2148148) Escherichia coli APEC O1 4492777 YP_853103.1 CDS APECO1_1083 NC_008563.1 2148049 2148456 R hypothetical protein complement(2148049..2148456) Escherichia coli APEC O1 4492778 YP_853104.1 CDS APECO1_1084 NC_008563.1 2148710 2149315 R hypothetical protein complement(2148710..2149315) Escherichia coli APEC O1 4492779 YP_853105.1 CDS APECO1_1085 NC_008563.1 2150106 2150429 D hypothetical protein 2150106..2150429 Escherichia coli APEC O1 4492780 YP_853106.1 CDS APECO1_1086 NC_008563.1 2150605 2151012 D transcriptional regulator 2150605..2151012 Escherichia coli APEC O1 4492781 YP_853107.1 CDS APECO1_1087 NC_008563.1 2151091 2151708 D hypothetical protein 2151091..2151708 Escherichia coli APEC O1 4492782 YP_853108.1 CDS APECO1_1088 NC_008563.1 2152251 2153102 R transposase subunit complement(2152251..2153102) Escherichia coli APEC O1 4492783 YP_853109.1 CDS APECO1_1089 NC_008563.1 2153099 2153620 R transposase subunit complement(2153099..2153620) Escherichia coli APEC O1 4492784 YP_853110.1 CDS APECO1_1090 NC_008563.1 2154070 2154345 D transposase subunit 2154070..2154345 Escherichia coli APEC O1 4492785 YP_853111.1 CDS APECO1_1091 NC_008563.1 2154572 2154916 R hypothetical protein complement(2154572..2154916) Escherichia coli APEC O1 4492786 YP_853112.1 CDS APECO1_1092 NC_008563.1 2155537 2156700 D hypothetical protein 2155537..2156700 Escherichia coli APEC O1 4492787 YP_853113.1 CDS APECO1_1093 NC_008563.1 2156745 2157656 D hypothetical protein 2156745..2157656 Escherichia coli APEC O1 4492788 YP_853114.1 CDS APECO1_1094 NC_008563.1 2157874 2160270 D hypothetical protein 2157874..2160270 Escherichia coli APEC O1 4492789 YP_853115.1 CDS APECO1_1095 NC_008563.1 2160267 2161172 D hypothetical protein 2160267..2161172 Escherichia coli APEC O1 4492790 YP_853116.1 CDS APECO1_1097 NC_008563.1 2161169 2162239 D esterase 2161169..2162239 Escherichia coli APEC O1 4492791 YP_853117.1 CDS APECO1_1098 NC_008563.1 2162267 2163058 D hypothetical protein 2162267..2163058 Escherichia coli APEC O1 4492792 YP_853118.1 CDS APECO1_1099 NC_008563.1 2163074 2163484 D hypothetical protein 2163074..2163484 Escherichia coli APEC O1 4492793 YP_853119.1 CDS APECO1_1100 NC_008563.1 2163701 2164540 R hypothetical protein complement(2163701..2164540) Escherichia coli APEC O1 4492794 YP_853120.1 CDS APECO1_1101 NC_008563.1 2164631 2165554 R hypothetical protein complement(2164631..2165554) Escherichia coli APEC O1 4492795 YP_853121.1 CDS yeeU NC_008563.1 2165924 2166292 D antitoxin of the YeeV-YeeU toxin-antitoxin system 2165924..2166292 Escherichia coli APEC O1 4491734 YP_853122.1 CDS yeeV NC_008563.1 2166381 2166644 D toxin of the YeeV-YeeU toxin-antitoxin system 2166381..2166644 Escherichia coli APEC O1 4491735 YP_853123.1 CDS yoeF NC_008563.1 2167386 2167742 D hypothetical protein 2167386..2167742 Escherichia coli APEC O1 4491736 YP_853124.1 CDS yeeX NC_008563.1 2167843 2168238 R hypothetical protein complement(2167843..2168238) Escherichia coli APEC O1 4491737 YP_853125.1 CDS yeeA NC_008563.1 2168344 2169402 R hypothetical protein complement(2168344..2169402) Escherichia coli APEC O1 4491738 YP_853126.1 CDS sbmC NC_008563.1 2169600 2170073 R DNA gyrase inhibitor complement(2169600..2170073) Escherichia coli APEC O1 4491739 YP_853127.1 CDS dacD NC_008563.1 2170192 2171235 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2170192..2171235) Escherichia coli APEC O1 4491740 YP_853128.1 CDS sbcB NC_008563.1 2171519 2172994 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2171519..2172994 Escherichia coli APEC O1 4491741 YP_853129.1 CDS yeeE NC_008563.1 2173278 2174336 R hypothetical protein complement(2173278..2174336) Escherichia coli APEC O1 4491742 YP_853130.1 CDS yeeF NC_008563.1 2174515 2175879 R amino acid transporter complement(2174515..2175879) Escherichia coli APEC O1 4491743 YP_853131.1 CDS yeeY NC_008563.1 2176140 2177090 R DNA-binding transcriptional regulator complement(2176140..2177090) Escherichia coli APEC O1 4491744 YP_853132.1 CDS yeeZ NC_008563.1 2177115 2177939 R epimerase complement(2177115..2177939) Escherichia coli APEC O1 4491745 YP_853133.1 CDS APECO1_1114 NC_008563.1 2178022 2178276 R hypothetical protein complement(2178022..2178276) Escherichia coli APEC O1 4491746 YP_853134.1 CDS yefM NC_008563.1 2178273 2178551 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2178273..2178551) Escherichia coli APEC O1 4491747 YP_853135.1 CDS hisG NC_008563.1 2178994 2179893 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2178994..2179893 Escherichia coli APEC O1 4491748 YP_853136.1 CDS hisD NC_008563.1 2179890 2181203 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2179890..2181203 Escherichia coli APEC O1 4491749 YP_853137.1 CDS hisC NC_008563.1 2181200 2182270 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2181200..2182270 Escherichia coli APEC O1 4491750 YP_853138.1 CDS hisB NC_008563.1 2182270 2183337 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2182270..2183337 Escherichia coli APEC O1 4491751 YP_853139.1 CDS hisH NC_008563.1 2183337 2183927 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2183337..2183927 Escherichia coli APEC O1 4491752 YP_853140.1 CDS hisA NC_008563.1 2183924 2184664 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2183924..2184664 Escherichia coli APEC O1 4491830 YP_853141.1 CDS hisF NC_008563.1 2184646 2185422 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2184646..2185422 Escherichia coli APEC O1 4491831 YP_853142.1 CDS hisI NC_008563.1 2185416 2186027 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2185416..2186027 Escherichia coli APEC O1 4491832 YP_853143.1 CDS cld NC_008563.1 2186123 2187139 R regulator of length of O-antigen component of lipopolysaccharide chains complement(2186123..2187139) Escherichia coli APEC O1 4491833 YP_853144.1 CDS ugd NC_008563.1 2187249 2188415 R UDP-glucose 6-dehydrogenase complement(2187249..2188415) Escherichia coli APEC O1 4491834 YP_853145.1 CDS gnd NC_008563.1 2188663 2190069 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2188663..2190069) Escherichia coli APEC O1 4491835 YP_853146.1 CDS APECO1_1127 NC_008563.1 2195479 2196705 R O-antigen transporter complement(2195479..2196705) Escherichia coli APEC O1 4491838 YP_853147.1 CDS rmlC NC_008563.1 2196749 2197297 R dTDP-4-dehydrorhamnose 3,5-epimerase complement(2196749..2197297) Escherichia coli APEC O1 4491839 YP_853148.1 CDS rmlA NC_008563.1 2197302 2198180 R glucose-1-phosphate thymidylyltransferase complement(2197302..2198180) Escherichia coli APEC O1 4491840 YP_853149.1 CDS rmlD NC_008563.1 2198238 2199137 R with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase complement(2198238..2199137) Escherichia coli APEC O1 4491841 YP_853150.1 CDS rfbB NC_008563.1 2199137 2200222 R NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase complement(2199137..2200222) Escherichia coli APEC O1 4491842 YP_853151.1 CDS galF NC_008563.1 2200595 2201500 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF complement(2200595..2201500) Escherichia coli APEC O1 4491843 YP_853152.1 CDS wcaM NC_008563.1 2201663 2203057 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2201663..2203057) Escherichia coli APEC O1 4491844 YP_853153.1 CDS wcaL NC_008563.1 2203068 2204288 R colanic acid biosynthesis glycosyl transferase complement(2203068..2204288) Escherichia coli APEC O1 4491845 YP_853154.1 CDS wcaK NC_008563.1 2204285 2205565 R pyruvyl transferase complement(2204285..2205565) Escherichia coli APEC O1 4491846 YP_853155.1 CDS wzxC NC_008563.1 2205727 2207205 R colanic acid exporter complement(2205727..2207205) Escherichia coli APEC O1 4491847 YP_853156.1 CDS wcaJ NC_008563.1 2207207 2208601 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2207207..2208601) Escherichia coli APEC O1 4491848 YP_853157.1 CDS cpsG NC_008563.1 2208656 2210026 R phosphomannomutase complement(2208656..2210026) Escherichia coli APEC O1 4491849 YP_853158.1 CDS cpsB NC_008563.1 2210128 2211564 R mannose-1-phosphate guanylyltransferase complement(2210128..2211564) Escherichia coli APEC O1 4494487 YP_853159.1 CDS wcaI NC_008563.1 2211567 2212790 R glycosyl transferase family protein complement(2211567..2212790) Escherichia coli APEC O1 4494488 YP_853160.1 CDS wcaH NC_008563.1 2212787 2213269 R GDP-mannose mannosyl hydrolase complement(2212787..2213269) Escherichia coli APEC O1 4494489 YP_853161.1 CDS wcaG NC_008563.1 2213269 2214234 R GDP-fucose synthetase complement(2213269..2214234) Escherichia coli APEC O1 4494490 YP_853162.1 CDS gmd NC_008563.1 2214237 2215358 R GDP-mannose 4,6-dehydratase complement(2214237..2215358) Escherichia coli APEC O1 4494491 YP_853163.1 CDS wcaF NC_008563.1 2215385 2215933 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2215385..2215933) Escherichia coli APEC O1 4494492 YP_853164.1 CDS wcaE NC_008563.1 2215949 2216695 R glycosyl transferase family protein complement(2215949..2216695) Escherichia coli APEC O1 4494493 YP_853165.2 CDS wcaD NC_008563.1 2216776 2217996 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2216776..2217996) Escherichia coli APEC O1 4494494 YP_853166.1 CDS wcaC NC_008563.1 2217971 2219188 R glycosyl transferase family protein complement(2217971..2219188) Escherichia coli APEC O1 4494495 YP_853167.1 CDS wcaB NC_008563.1 2219185 2219673 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2219185..2219673) Escherichia coli APEC O1 4494496 YP_853168.1 CDS wcaA NC_008563.1 2219676 2220515 R glycosyl transferase family protein complement(2219676..2220515) Escherichia coli APEC O1 4494497 YP_853169.1 CDS wzc NC_008563.1 2220644 2222842 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2220644..2222842) Escherichia coli APEC O1 4494498 YP_853170.1 CDS wzb NC_008563.1 2222809 2223252 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2222809..2223252) Escherichia coli APEC O1 4494499 YP_853171.1 CDS wza NC_008563.1 2223258 2224397 R polysaccharide export protein complement(2223258..2224397) Escherichia coli APEC O1 4494500 YP_853172.1 CDS yegH NC_008563.1 2225017 2226639 D hypothetical protein 2225017..2226639 Escherichia coli APEC O1 4494501 YP_853173.1 CDS APECO1_1154 NC_008563.1 2226714 2227052 D hypothetical protein 2226714..2227052 Escherichia coli APEC O1 4494502 YP_853174.1 CDS asmA NC_008563.1 2227385 2229238 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2227385..2229238) Escherichia coli APEC O1 4494503 YP_853175.1 CDS dcd NC_008563.1 2229260 2229841 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2229260..2229841) Escherichia coli APEC O1 4494504 YP_853176.1 CDS udk NC_008563.1 2229933 2230574 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2229933..2230574) Escherichia coli APEC O1 4494505 YP_853177.1 CDS yegE NC_008563.1 2230892 2234209 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2230892..2234209 Escherichia coli APEC O1 4494349 YP_853178.1 CDS alkA NC_008563.1 2234320 2235168 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2234320..2235168) Escherichia coli APEC O1 4494350 YP_853179.1 CDS yegD NC_008563.1 2235302 2236654 D chaperone 2235302..2236654 Escherichia coli APEC O1 4494351 YP_853180.1 CDS yedI NC_008563.1 2236667 2238616 R hypothetical protein complement(2236667..2238616) Escherichia coli APEC O1 4494352 YP_853181.1 CDS yedK NC_008563.1 2238604 2239365 R hypothetical protein complement(2238604..2239365) Escherichia coli APEC O1 4494353 YP_853182.1 CDS yedL NC_008563.1 2239362 2240021 R hypothetical protein complement(2239362..2240021) Escherichia coli APEC O1 4494354 YP_853183.1 CDS yegM NC_008563.1 2240755 2242149 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2240755..2242149 Escherichia coli APEC O1 4494355 YP_853184.1 CDS yegN NC_008563.1 2242149 2245271 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2242149..2245271 Escherichia coli APEC O1 4494356 YP_853185.1 CDS yegO NC_008563.1 2245272 2248349 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2245272..2248349 Escherichia coli APEC O1 4494357 YP_853186.1 CDS yegB NC_008563.1 2248350 2249765 D multidrug efflux system protein MdtE 2248350..2249765 Escherichia coli APEC O1 4494358 YP_853187.1 CDS baeS NC_008563.1 2249762 2251165 D signal transduction histidine-protein kinase BaeS 2249762..2251165 Escherichia coli APEC O1 4494359 YP_853188.1 CDS APECO1_1169 NC_008563.1 2251162 2251884 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2251162..2251884 Escherichia coli APEC O1 4494360 YP_853189.1 CDS yegP NC_008563.1 2252025 2252396 D hypothetical protein 2252025..2252396 Escherichia coli APEC O1 4494361 YP_853190.1 CDS APECO1_1171 NC_008563.1 2252521 2253135 R hypothetical protein complement(2252521..2253135) Escherichia coli APEC O1 4494362 YP_853191.1 CDS APECO1_1172 NC_008563.1 2253187 2253495 R hypothetical protein complement(2253187..2253495) Escherichia coli APEC O1 4494363 YP_853192.1 CDS APECO1_1173 NC_008563.1 2253621 2255333 R hypothetical protein complement(2253621..2255333) Escherichia coli APEC O1 4494364 YP_853193.1 CDS APECO1_1174 NC_008563.1 2255305 2256021 R hypothetical protein complement(2255305..2256021) Escherichia coli APEC O1 4494365 YP_853194.1 CDS APECO1_1175 NC_008563.1 2256021 2257235 R hypothetical protein complement(2256021..2257235) Escherichia coli APEC O1 4494366 YP_853195.1 CDS yegQ NC_008563.1 2257723 2259084 D hypothetical protein 2257723..2259084 Escherichia coli APEC O1 4494367 YP_853196.1 CDS APECO1_1177 NC_008563.1 2259657 2260820 R phage protein D complement(2259657..2260820) Escherichia coli APEC O1 4494368 YP_853197.1 CDS APECO1_1178 NC_008563.1 2260820 2261299 R phage protein U complement(2260820..2261299) Escherichia coli APEC O1 4493927 YP_853198.1 CDS APECO1_1179 NC_008563.1 2261314 2263761 R phage related tail protein complement(2261314..2263761) Escherichia coli APEC O1 4493928 YP_853199.1 CDS gpP NC_008563.1 2270959 2272731 D Phage protein P 2270959..2272731 Escherichia coli APEC O1 4493929 YP_853200.1 CDS gpQ NC_008563.1 2272731 2273765 D Phage protein Q 2272731..2273765 Escherichia coli APEC O1 4493930 YP_853201.1 CDS APECO1_1182 NC_008563.1 2274092 2275141 D hypothetical protein 2274092..2275141 Escherichia coli APEC O1 4493931 YP_853202.1 CDS APECO1_1183 NC_008563.1 2275134 2276417 D hypothetical protein 2275134..2276417 Escherichia coli APEC O1 4493932 YP_853203.1 CDS gpA NC_008563.1 2276593 2278848 R Phage protein A complement(2276593..2278848) Escherichia coli APEC O1 4493933 YP_853204.1 CDS APECO1_1185 NC_008563.1 2279337 2279636 R hypothetical protein complement(2279337..2279636) Escherichia coli APEC O1 4493934 YP_853205.1 CDS gpB NC_008563.1 2279924 2280430 R Phage protein B complement(2279924..2280430) Escherichia coli APEC O1 4493935 YP_853206.1 CDS gpC NC_008563.1 2280992 2281291 D phage-associated; immunity repressor 2280992..2281291 Escherichia coli APEC O1 4493936 YP_853207.1 CDS APECO1_4458 NC_008563.1 2281407 2282420 D phage integrase 2281407..2282420 Escherichia coli APEC O1 4493937 YP_853208.1 CDS yegR NC_008563.1 2282855 2283232 R hypothetical protein complement(2282855..2283232) Escherichia coli APEC O1 4493938 YP_853209.1 CDS APECO1_4456 NC_008563.1 2283588 2284487 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2283588..2284487 Escherichia coli APEC O1 4493939 YP_853210.1 CDS gatR NC_008563.1 2284569 2285348 R galactitol utilization operon repressor complement(2284569..2285348) Escherichia coli APEC O1 4493940 YP_853211.1 CDS gatD NC_008563.1 2285448 2286488 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2285448..2286488) Escherichia coli APEC O1 4493941 YP_853212.1 CDS gatC NC_008563.1 2286536 2287891 R PTS system galactitol-specific transporter subunit IIC complement(2286536..2287891) Escherichia coli APEC O1 4493942 YP_853213.1 CDS gatB NC_008563.1 2287895 2288179 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2287895..2288179) Escherichia coli APEC O1 4493943 YP_853214.1 CDS gatA NC_008563.1 2288210 2288662 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2288210..2288662) Escherichia coli APEC O1 4493944 YP_853215.1 CDS gatZ NC_008563.1 2288672 2289934 R tagatose 6-phosphate kinase GatZ complement(2288672..2289934) Escherichia coli APEC O1 4493945 YP_853216.1 CDS gatY NC_008563.1 2289963 2290817 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2289963..2290817) Escherichia coli APEC O1 4494506 YP_853217.1 CDS APECO1_4448 NC_008563.1 2291046 2292170 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2291046..2292170) Escherichia coli APEC O1 4494507 YP_853218.1 CDS yegT NC_008563.1 2292355 2293632 D nucleoside transporter 2292355..2293632 Escherichia coli APEC O1 4494508 YP_853219.1 CDS yegW NC_008563.1 2293629 2294633 D hydrolase 2293629..2294633 Escherichia coli APEC O1 4494509 YP_853220.1 CDS yegV NC_008563.1 2294630 2295595 D sugar kinase 2294630..2295595 Escherichia coli APEC O1 4494510 YP_853221.1 CDS yegW NC_008563.1 2295569 2296315 R transcriptional regulator complement(2295569..2296315) Escherichia coli APEC O1 4494511 YP_853222.1 CDS yegX NC_008563.1 2296367 2297194 R hypothetical protein complement(2296367..2297194) Escherichia coli APEC O1 4494512 YP_853223.1 CDS thiD NC_008563.1 2297250 2298050 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2297250..2298050) Escherichia coli APEC O1 4494513 YP_853224.1 CDS thiM NC_008563.1 2298047 2298835 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2298047..2298835) Escherichia coli APEC O1 4494514 YP_853225.1 CDS yohL NC_008563.1 2299451 2300275 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2299451..2300275 Escherichia coli APEC O1 4494515 YP_853226.1 CDS yohN NC_008563.1 2300314 2300832 D hypothetical protein 2300314..2300832 Escherichia coli APEC O1 4494516 YP_853227.1 CDS yehA NC_008563.1 2300914 2301948 R fimbrial-like adhesin protein complement(2300914..2301948) Escherichia coli APEC O1 4494517 YP_853228.1 CDS yehB NC_008563.1 2301964 2304444 R outer membrane usher protein YehB complement(2301964..2304444) Escherichia coli APEC O1 4494518 YP_853229.1 CDS yehC NC_008563.1 2304460 2305134 R fimbrial chaperone YehC complement(2304460..2305134) Escherichia coli APEC O1 4494519 YP_853230.1 CDS yehD NC_008563.1 2306051 2306332 R fimbrial-like adhesin protein complement(2306051..2306332) Escherichia coli APEC O1 4494520 YP_853231.1 CDS mrp NC_008563.1 2306595 2307734 R ATPase complement(2306595..2307734) Escherichia coli APEC O1 4494521 YP_853232.1 CDS metG NC_008563.1 2307827 2309869 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2307827..2309869 Escherichia coli APEC O1 4494522 YP_853233.1 CDS APECO1_4432 NC_008563.1 2310010 2313798 D hypothetical protein 2310010..2313798 Escherichia coli APEC O1 4494523 YP_853234.1 CDS yehI NC_008563.1 2314086 2317439 D hypothetical protein 2314086..2317439 Escherichia coli APEC O1 4494524 YP_853235.1 CDS yehL NC_008563.1 2318530 2319684 D ATPase 2318530..2319684 Escherichia coli APEC O1 4494525 YP_853236.1 CDS yehM NC_008563.1 2319691 2321967 D hypothetical protein 2319691..2321967 Escherichia coli APEC O1 4494698 YP_853237.1 CDS yehN NC_008563.1 2321750 2323096 D hypothetical protein 2321750..2323096 Escherichia coli APEC O1 4494699 YP_853238.1 CDS yehQ NC_008563.1 2323093 2325096 D hypothetical protein 2323093..2325096 Escherichia coli APEC O1 4494700 YP_853239.1 CDS yehR NC_008563.1 2325209 2325682 D hypothetical protein 2325209..2325682 Escherichia coli APEC O1 4494701 YP_853240.1 CDS yehS NC_008563.1 2325723 2326193 R hypothetical protein complement(2325723..2326193) Escherichia coli APEC O1 4494702 YP_853241.1 CDS yehT NC_008563.1 2326240 2326974 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2326240..2326974) Escherichia coli APEC O1 4494703 YP_853242.1 CDS yehU NC_008563.1 2326956 2328641 R sensory kinase in two-component system with YehT complement(2326956..2328641) Escherichia coli APEC O1 4494704 YP_853243.1 CDS yehV NC_008563.1 2328863 2329594 D MerR family transcriptional regulator 2328863..2329594 Escherichia coli APEC O1 4494705 YP_853244.1 CDS yehW NC_008563.1 2329742 2330473 R transporter subunit membrane protein complement(2329742..2330473) Escherichia coli APEC O1 4494706 YP_853245.1 CDS yehX NC_008563.1 2330478 2331404 R transporter subunit ATP-binding protein complement(2330478..2331404) Escherichia coli APEC O1 4494707 YP_853246.1 CDS yehY NC_008563.1 2331397 2332554 R transporter subunit membrane protein complement(2331397..2332554) Escherichia coli APEC O1 4494708 YP_853247.1 CDS yehZ NC_008563.1 2332561 2333478 R transporter subunit periplasmic-binding protein complement(2332561..2333478) Escherichia coli APEC O1 4494709 YP_853248.1 CDS bglX NC_008563.1 2333668 2336037 R beta-D-glucoside glucohydrolase-like protein complement(2333668..2336037) Escherichia coli APEC O1 4494710 YP_853249.1 CDS dld NC_008563.1 2336170 2337876 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2336170..2337876 Escherichia coli APEC O1 4494711 YP_853250.1 CDS pbpG NC_008563.1 2337915 2338856 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2337915..2338856) Escherichia coli APEC O1 4494712 YP_853251.1 CDS yohC NC_008563.1 2339021 2339632 R hypothetical protein complement(2339021..2339632) Escherichia coli APEC O1 4494713 YP_853252.1 CDS yohD NC_008563.1 2339742 2340356 D hypothetical protein 2339742..2340356 Escherichia coli APEC O1 4494714 YP_853253.1 CDS yohF NC_008563.1 2340476 2341237 R acetoin dehydrogenase complement(2340476..2341237) Escherichia coli APEC O1 4494715 YP_853254.1 CDS yohG NC_008563.1 2341290 2342807 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2341290..2342807) Escherichia coli APEC O1 4491636 YP_853255.1 CDS dusC NC_008563.1 2343421 2344371 R tRNA-dihydrouridine synthase C complement(2343421..2344371) Escherichia coli APEC O1 4491637 YP_853256.1 CDS yohJ NC_008563.1 2344610 2345008 D hypothetical protein 2344610..2345008 Escherichia coli APEC O1 4491638 YP_853257.1 CDS yohK NC_008563.1 2345005 2345700 D hypothetical protein 2345005..2345700 Escherichia coli APEC O1 4491639 YP_853258.1 CDS cdd NC_008563.1 2345830 2346714 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2345830..2346714 Escherichia coli APEC O1 4491640 YP_853259.1 CDS sanA NC_008563.1 2346864 2347583 D hypothetical protein 2346864..2347583 Escherichia coli APEC O1 4491641 YP_853260.1 CDS yeiT NC_008563.1 2348019 2349257 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2348019..2349257 Escherichia coli APEC O1 4491642 YP_853261.1 CDS yeiA NC_008563.1 2349251 2350486 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2349251..2350486 Escherichia coli APEC O1 4491643 YP_853262.1 CDS mglC NC_008563.1 2350729 2351739 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2350729..2351739) Escherichia coli APEC O1 4491644 YP_853263.1 CDS mglA NC_008563.1 2351755 2353275 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2351755..2353275) Escherichia coli APEC O1 4491645 YP_853264.1 CDS mglB NC_008563.1 2353336 2354334 R methyl-galactoside transporter subunit MglB complement(2353336..2354334) Escherichia coli APEC O1 4491646 YP_853265.1 CDS galS NC_008563.1 2354614 2355654 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2354614..2355654) Escherichia coli APEC O1 4491647 YP_853266.1 CDS APECO1_4399 NC_008563.1 2355796 2356953 R hypothetical protein complement(2355796..2356953) Escherichia coli APEC O1 4491648 YP_853267.1 CDS folE NC_008563.1 2356970 2357638 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2356970..2357638) Escherichia coli APEC O1 4491649 YP_853268.1 CDS yeiG NC_008563.1 2357896 2358732 D esterase 2357896..2358732 Escherichia coli APEC O1 4491650 YP_853269.2 CDS cirA NC_008563.1 2358764 2360755 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2358764..2360755) Escherichia coli APEC O1 4491651 YP_853270.1 CDS lysP NC_008563.1 2360961 2362430 R lysine transporter complement(2360961..2362430) Escherichia coli APEC O1 4491652 YP_853271.1 CDS yeiE NC_008563.1 2362635 2363516 R DNA-binding transcriptional regulator complement(2362635..2363516) Escherichia coli APEC O1 4491653 YP_853272.1 CDS yeiH NC_008563.1 2364738 2365595 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2364738..2365595 Escherichia coli APEC O1 4491654 YP_853273.1 CDS yeiI NC_008563.1 2365599 2366687 D hypothetical protein 2365599..2366687 Escherichia coli APEC O1 4491655 YP_853274.1 CDS rihB NC_008563.1 2366955 2367896 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2366955..2367896) Escherichia coli APEC O1 4493966 YP_853275.1 CDS yeiL NC_008563.1 2368065 2368724 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2368065..2368724 Escherichia coli APEC O1 4493967 YP_853276.1 CDS yeiM NC_008563.1 2368791 2370041 R nucleoside transporter complement(2368791..2370041) Escherichia coli APEC O1 4493968 YP_853277.1 CDS yeiN NC_008563.1 2370135 2371073 R hypothetical protein complement(2370135..2371073) Escherichia coli APEC O1 4493969 YP_853278.1 CDS yeiC NC_008563.1 2371061 2372116 R hypothetical protein complement(2371061..2372116) Escherichia coli APEC O1 4493970 YP_853279.1 CDS fruA NC_008563.1 2372458 2374149 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2372458..2374149) Escherichia coli APEC O1 4493971 YP_853280.1 CDS fruK NC_008563.1 2374166 2375104 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2374166..2375104) Escherichia coli APEC O1 4493972 YP_853281.1 CDS APECO1_4385 NC_008563.1 2375104 2376234 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2375104..2376234) Escherichia coli APEC O1 4493973 YP_853282.1 CDS yeiO NC_008563.1 2376601 2377782 D sugar efflux transporter B 2376601..2377782 Escherichia coli APEC O1 4493974 YP_853283.1 CDS APECO1_4383 NC_008563.1 2377933 2378760 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2377933..2378760 Escherichia coli APEC O1 4493975 YP_853284.1 CDS yeiQ NC_008563.1 2378983 2380449 D dehydrogenase, NAD-dependent 2378983..2380449 Escherichia coli APEC O1 4493976 YP_853285.1 CDS yeiR NC_008563.1 2380567 2381553 D hypothetical protein 2380567..2381553 Escherichia coli APEC O1 4493977 YP_853286.1 CDS yeiU NC_008563.1 2381592 2382305 D undecaprenyl pyrophosphate phosphatase 2381592..2382305 Escherichia coli APEC O1 4493978 YP_853287.1 CDS spr NC_008563.1 2382717 2383283 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2382717..2383283 Escherichia coli APEC O1 4493979 YP_853288.1 CDS APECO1_4378 NC_008563.1 2383464 2385020 D hypothetical protein 2383464..2385020 Escherichia coli APEC O1 4493980 YP_853289.1 CDS yejA NC_008563.1 2385102 2386916 D hypothetical protein 2385102..2386916 Escherichia coli APEC O1 4493981 YP_853290.1 CDS yejB NC_008563.1 2386917 2388011 D oligopeptide transporter subunit 2386917..2388011 Escherichia coli APEC O1 4493982 YP_853291.1 CDS yejE NC_008563.1 2388011 2389036 D oligopeptide transporter subunit 2388011..2389036 Escherichia coli APEC O1 4493983 YP_853292.1 CDS yejF NC_008563.1 2389038 2390627 D ABC transporter ATP-binding protein 2389038..2390627 Escherichia coli APEC O1 4493984 YP_853293.1 CDS bcr NC_008563.1 2391309 2392442 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2391309..2392442) Escherichia coli APEC O1 4495174 YP_853294.1 CDS rsuA NC_008563.1 2392527 2393222 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2392527..2393222) Escherichia coli APEC O1 4495175 YP_853295.1 CDS yejH NC_008563.1 2393372 2395132 D ATP-dependet helicase 2393372..2395132 Escherichia coli APEC O1 4495176 YP_853297.1 CDS yejK NC_008563.1 2395680 2396687 R nucleoid-associated protein NdpA complement(2395680..2396687) Escherichia coli APEC O1 4495178 YP_853298.1 CDS yejM NC_008563.1 2397116 2398876 D hydrolase, inner membrane 2397116..2398876 Escherichia coli APEC O1 4495179 YP_853299.1 CDS yejO NC_008563.1 2399129 2399614 R autotransporter outer membrane protein complement(2399129..2399614) Escherichia coli APEC O1 4495180 YP_853300.1 CDS APECO1_4366 NC_008563.1 2399957 2400214 R hypothetical protein complement(2399957..2400214) Escherichia coli APEC O1 4495181 YP_853301.1 CDS narP NC_008563.1 2400216 2400893 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2400216..2400893 Escherichia coli APEC O1 4495182 YP_853302.1 CDS ccmH NC_008563.1 2400928 2401980 R heme lyase, CcmH subunit complement(2400928..2401980) Escherichia coli APEC O1 4495183 YP_853303.1 CDS ccmG NC_008563.1 2401977 2402534 R periplasmic thioredoxin of cytochrome c-type biogenesis complement(2401977..2402534) Escherichia coli APEC O1 4495184 YP_853304.1 CDS ccmF NC_008563.1 2402531 2404474 R heme lyase, CcmF subunit complement(2402531..2404474) Escherichia coli APEC O1 4495185 YP_853305.1 CDS ccmE NC_008563.1 2404471 2404950 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2404471..2404950) Escherichia coli APEC O1 4495186 YP_853306.1 CDS ccmC NC_008563.1 2405153 2405890 R heme exporter protein C complement(2405153..2405890) Escherichia coli APEC O1 4495187 YP_853307.1 CDS ccmB NC_008563.1 2405932 2406594 R heme exporter protein B complement(2405932..2406594) Escherichia coli APEC O1 4495188 YP_853308.1 CDS ccmA NC_008563.1 2406591 2407214 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2406591..2407214) Escherichia coli APEC O1 4495189 YP_853309.1 CDS napC NC_008563.1 2407227 2407829 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2407227..2407829) Escherichia coli APEC O1 4495190 YP_853310.1 CDS napB NC_008563.1 2407839 2408309 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2407839..2408309) Escherichia coli APEC O1 4493245 YP_853311.1 CDS napH NC_008563.1 2408285 2409148 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2408285..2409148) Escherichia coli APEC O1 4493246 YP_853312.1 CDS napG NC_008563.1 2409135 2409830 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2409135..2409830) Escherichia coli APEC O1 4493247 YP_853313.1 CDS napA NC_008563.1 2409837 2412323 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2409837..2412323) Escherichia coli APEC O1 4493248 YP_853314.1 CDS napD NC_008563.1 2412320 2412583 R assembly protein for periplasmic nitrate reductase complement(2412320..2412583) Escherichia coli APEC O1 4493249 YP_853315.1 CDS napF NC_008563.1 2412573 2413067 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(2412573..2413067) Escherichia coli APEC O1 4493250 YP_853316.1 CDS eco NC_008563.1 2413655 2414113 R ecotin complement(2413655..2414113) Escherichia coli APEC O1 4493251 YP_853317.1 CDS mqo NC_008563.1 2414113 2415759 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2414113..2415759) Escherichia coli APEC O1 4493252 YP_853318.1 CDS yojI NC_008563.1 2415977 2417620 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component complement(2415977..2417620) Escherichia coli APEC O1 4493253 YP_853319.1 CDS alkB NC_008563.1 2417696 2418346 R AlkB repair system protein for alkylated DNA and RNA complement(2417696..2418346) Escherichia coli APEC O1 4493254 YP_853320.1 CDS ada NC_008563.1 2418346 2419410 R Ada transcriptional dual regulator / O-6-methylguanine-DNA methyltransferase complement(2418346..2419410) Escherichia coli APEC O1 4493255 YP_853321.1 CDS yojL NC_008563.1 2419484 2420539 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2419484..2420539) Escherichia coli APEC O1 4493256 YP_853322.1 CDS ompC NC_008563.1 2420651 2421742 R OmpC; allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2420651..2421742) Escherichia coli APEC O1 4493257 YP_853323.1 CDS yojN NC_008563.1 2422481 2425153 D phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2422481..2425153 Escherichia coli APEC O1 4493258 YP_853324.1 CDS rcsB NC_008563.1 2425170 2425820 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2425170..2425820 Escherichia coli APEC O1 4493259 YP_853325.1 CDS rcsC NC_008563.1 2426020 2428821 R hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2426020..2428821) Escherichia coli APEC O1 4493260 YP_853326.1 CDS atoS NC_008563.1 2429036 2430862 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2429036..2430862 Escherichia coli APEC O1 4493261 YP_853327.1 CDS atoC NC_008563.1 2430859 2432244 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2430859..2432244 Escherichia coli APEC O1 4492564 YP_853328.1 CDS atoD NC_008563.1 2432440 2433102 D acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2432440..2433102 Escherichia coli APEC O1 4492567 YP_853329.1 CDS atoA NC_008563.1 2433102 2433752 D acetyl-CoA:acetoacetyl-CoA transferase subunit beta 2433102..2433752 Escherichia coli APEC O1 4492568 YP_853330.1 CDS atoE NC_008563.1 2433749 2435071 D short chain fatty acid transporter 2433749..2435071 Escherichia coli APEC O1 4492569 YP_853331.1 CDS atoB NC_008563.1 2435102 2435410 D authentic frameshift; acetyl-CoA acetyltransferase 2435102..2435410 Escherichia coli APEC O1 4492570 YP_853332.1 CDS atoB NC_008563.1 2435432 2436286 D authentic frameshift; acetyl-CoA acetyltransferase 2435432..2436286 Escherichia coli APEC O1 4492571 YP_853333.1 CDS yfaP NC_008563.1 2436360 2437136 R hypothetical protein complement(2436360..2437136) Escherichia coli APEC O1 4492572 YP_853334.1 CDS yfaQ NC_008563.1 2437141 2438790 R hypothetical protein complement(2437141..2438790) Escherichia coli APEC O1 4492573 YP_853335.1 CDS yfaS NC_008563.1 2438791 2443395 R hypothetical protein complement(2438791..2443395) Escherichia coli APEC O1 4492574 YP_853336.1 CDS yfaT NC_008563.1 2443329 2443952 R hypothetical protein complement(2443329..2443952) Escherichia coli APEC O1 4492575 YP_853337.1 CDS yfaA NC_008563.1 2443949 2445637 R hypothetical protein complement(2443949..2445637) Escherichia coli APEC O1 4492576 YP_853338.1 CDS gyrA NC_008563.1 2445786 2448413 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2445786..2448413) Escherichia coli APEC O1 4492577 YP_853339.1 CDS ubiG NC_008563.1 2448512 2449282 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2448512..2449282 Escherichia coli APEC O1 4492578 YP_853340.1 CDS APECO1_4327 NC_008563.1 2449422 2453186 R adhesin complement(2449422..2453186) Escherichia coli APEC O1 4492579 YP_853341.1 CDS nrdA NC_008563.1 2453862 2456147 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2453862..2456147 Escherichia coli APEC O1 4492580 YP_853342.1 CDS nrdB NC_008563.1 2456162 2457424 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2456162..2457424 Escherichia coli APEC O1 4492581 YP_853343.1 CDS yfaE NC_008563.1 2457424 2457678 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2457424..2457678 Escherichia coli APEC O1 4494546 YP_853344.1 CDS inaA NC_008563.1 2457732 2458382 R hypothetical protein complement(2457732..2458382) Escherichia coli APEC O1 4494547 YP_853345.1 CDS glpQ NC_008563.1 2458585 2459661 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2458585..2459661) Escherichia coli APEC O1 4494548 YP_853346.1 CDS glpT NC_008563.1 2459666 2461024 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2459666..2461024) Escherichia coli APEC O1 4494549 YP_853347.1 CDS glpA NC_008563.1 2461297 2462925 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2461297..2462925 Escherichia coli APEC O1 4494550 YP_853348.1 CDS glpB NC_008563.1 2462915 2464174 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2462915..2464174 Escherichia coli APEC O1 4494551 YP_853349.1 CDS glpC NC_008563.1 2464171 2465361 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2464171..2465361 Escherichia coli APEC O1 4494552 YP_853350.1 CDS yfaD NC_008563.1 2465554 2466513 D hypothetical protein 2465554..2466513 Escherichia coli APEC O1 4494553 YP_853351.1 CDS yfaU NC_008563.1 2466752 2467555 R aldolase complement(2466752..2467555) Escherichia coli APEC O1 4494554 YP_853352.1 CDS yfaV NC_008563.1 2467573 2468901 R hypothetical protein complement(2467573..2468901) Escherichia coli APEC O1 4494555 YP_853353.1 CDS yfaW NC_008563.1 2468919 2470136 R hypothetical protein complement(2468919..2470136) Escherichia coli APEC O1 4494556 YP_853354.1 CDS yfaX NC_008563.1 2470139 2470921 R transcriptional regulator YfaX complement(2470139..2470921) Escherichia coli APEC O1 4494557 YP_853355.1 CDS cinA NC_008563.1 2471141 2472343 R competence damage-inducible protein A complement(2471141..2472343) Escherichia coli APEC O1 4494558 YP_853356.1 CDS yfaZ NC_008563.1 2472443 2473000 R hypothetical protein complement(2472443..2473000) Escherichia coli APEC O1 4494559 YP_853357.1 CDS yfaO NC_008563.1 2473264 2473689 D Nudix hydrolase YfaO 2473264..2473689 Escherichia coli APEC O1 4494560 YP_853358.1 CDS ais NC_008563.1 2473728 2474330 R aluminum inducible protein Ais complement(2473728..2474330) Escherichia coli APEC O1 4494561 YP_853359.1 CDS yfbE NC_008563.1 2474605 2475777 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2474605..2475777 Escherichia coli APEC O1 4494562 YP_853360.1 CDS yfbF NC_008563.1 2475781 2476749 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2475781..2476749 Escherichia coli APEC O1 4494563 YP_853361.1 CDS yfbG NC_008563.1 2476749 2478731 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2476749..2478731 Escherichia coli APEC O1 4494564 YP_853362.1 CDS yfbH NC_008563.1 2478728 2479618 D hypothetical protein 2478728..2479618 Escherichia coli APEC O1 4492503 YP_853363.1 CDS arnT NC_008563.1 2479618 2481270 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2479618..2481270 Escherichia coli APEC O1 4492504 YP_853364.2 CDS yfbJ NC_008563.1 2481602 2481988 D hypothetical protein 2481602..2481988 Escherichia coli APEC O1 4492505 YP_853365.1 CDS pmrD NC_008563.1 2481982 2482278 R polymyxin B resistance protein PmrD complement(2481982..2482278) Escherichia coli APEC O1 4492506 YP_853366.1 CDS menE NC_008563.1 2482358 2483713 R O-succinylbenzoic acid--CoA ligase complement(2482358..2483713) Escherichia coli APEC O1 4492507 YP_853367.1 CDS menC NC_008563.1 2483710 2484672 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2483710..2484672) Escherichia coli APEC O1 4492508 YP_853368.1 CDS menB NC_008563.1 2484672 2485529 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2484672..2485529) Escherichia coli APEC O1 4492509 YP_853369.1 CDS yfbB NC_008563.1 2485544 2486302 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(2485544..2486302) Escherichia coli APEC O1 4492510 YP_853370.1 CDS menD NC_008563.1 2486299 2488158 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2486299..2488158) Escherichia coli APEC O1 4492511 YP_853371.1 CDS menF NC_008563.1 2488058 2489353 R menaquinone-specific isochorismate synthase complement(2488058..2489353) Escherichia coli APEC O1 4492512 YP_853372.1 CDS elaB NC_008563.1 2489432 2489737 R hypothetical protein complement(2489432..2489737) Escherichia coli APEC O1 4492513 YP_853373.1 CDS elaA NC_008563.1 2489792 2490253 R hypothetical protein complement(2489792..2490253) Escherichia coli APEC O1 4492514 YP_853374.1 CDS elaC NC_008563.1 2490318 2491235 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2490318..2491235 Escherichia coli APEC O1 4492515 YP_853375.1 CDS yfbK NC_008563.1 2491356 2493098 R hypothetical protein complement(2491356..2493098) Escherichia coli APEC O1 4492516 YP_853376.1 CDS yfbL NC_008563.1 2493236 2494207 D hypothetical protein 2493236..2494207 Escherichia coli APEC O1 4492517 YP_853377.1 CDS yfbM NC_008563.1 2494310 2494813 D hypothetical protein 2494310..2494813 Escherichia coli APEC O1 4492518 YP_853378.1 CDS nuoN NC_008563.1 2494880 2496337 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2494880..2496337) Escherichia coli APEC O1 4492519 YP_853379.1 CDS nuoM NC_008563.1 2496344 2497873 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2496344..2497873) Escherichia coli APEC O1 4492520 YP_853380.1 CDS nuoL NC_008563.1 2498037 2499878 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2498037..2499878) Escherichia coli APEC O1 4492521 YP_853381.1 CDS nuoK NC_008563.1 2499875 2500177 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2499875..2500177) Escherichia coli APEC O1 4492522 YP_853382.1 CDS nuoJ NC_008563.1 2500174 2500728 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2500174..2500728) Escherichia coli APEC O1 4495517 YP_853383.1 CDS nuoI NC_008563.1 2500740 2501282 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2500740..2501282) Escherichia coli APEC O1 4495518 YP_853384.1 CDS nuoH NC_008563.1 2501297 2502274 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2501297..2502274) Escherichia coli APEC O1 4495519 YP_853385.1 CDS nuoG NC_008563.1 2502271 2505003 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2502271..2505003) Escherichia coli APEC O1 4495520 YP_853386.1 CDS nuoF NC_008563.1 2505050 2506387 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2505050..2506387) Escherichia coli APEC O1 4495521 YP_853387.1 CDS nuoE NC_008563.1 2506384 2506884 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2506384..2506884) Escherichia coli APEC O1 4495522 YP_853388.1 CDS nuoC NC_008563.1 2506887 2508689 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2506887..2508689) Escherichia coli APEC O1 4495523 YP_853389.1 CDS nuoB NC_008563.1 2508783 2509445 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2508783..2509445) Escherichia coli APEC O1 4495524 YP_853390.1 CDS nuoA NC_008563.1 2509461 2509904 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2509461..2509904) Escherichia coli APEC O1 4495525 YP_853391.1 CDS APECO1_4276 NC_008563.1 2510051 2510320 R hypothetical protein complement(2510051..2510320) Escherichia coli APEC O1 4495526 YP_853392.1 CDS lrhA NC_008563.1 2510534 2511472 R DNA-binding transcriptional repressor of flagellar, motility and chemotaxis protein complement(2510534..2511472) Escherichia coli APEC O1 4495527 YP_853393.1 CDS yfbQ NC_008563.1 2512392 2513609 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2512392..2513609 Escherichia coli APEC O1 4495528 YP_853394.1 CDS yfbR NC_008563.1 2513693 2514292 D hypothetical protein 2513693..2514292 Escherichia coli APEC O1 4495530 YP_853395.1 CDS yfbS NC_008563.1 2514351 2516183 R di- and tricarboxylate transporter complement(2514351..2516183) Escherichia coli APEC O1 4495531 YP_853396.1 CDS yfbT NC_008563.1 2516270 2516920 R phosphatase complement(2516270..2516920) Escherichia coli APEC O1 4495532 YP_853397.1 CDS yfbU NC_008563.1 2516931 2517443 R hypothetical protein complement(2516931..2517443) Escherichia coli APEC O1 4495533 YP_853398.1 CDS yfbV NC_008563.1 2517508 2517963 R hypothetical protein complement(2517508..2517963) Escherichia coli APEC O1 4495534 YP_853399.1 CDS ackA NC_008563.1 2518301 2519503 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2518301..2519503 Escherichia coli APEC O1 4495535 YP_853401.1 CDS yfcC NC_008563.1 2521891 2523432 D hypothetical protein 2521891..2523432 Escherichia coli APEC O1 4493568 YP_853402.1 CDS yfcD NC_008563.1 2523465 2524007 R NUDIX hydrolase complement(2523465..2524007) Escherichia coli APEC O1 4493569 YP_853403.1 CDS yfcE NC_008563.1 2524065 2524619 R phosphodiesterase complement(2524065..2524619) Escherichia coli APEC O1 4493570 YP_853404.1 CDS yfcF NC_008563.1 2524672 2525316 R glutathione S-transferase complement(2524672..2525316) Escherichia coli APEC O1 4493571 YP_853405.1 CDS yfcG NC_008563.1 2525452 2526099 D glutathione S-transferase 2525452..2526099 Escherichia coli APEC O1 4493572 YP_853406.1 CDS folX NC_008563.1 2526156 2526518 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2526156..2526518 Escherichia coli APEC O1 4493573 YP_853407.1 CDS yfcH NC_008563.1 2526539 2527432 D sugar nucleotide epimerase 2526539..2527432 Escherichia coli APEC O1 4493574 YP_853408.1 CDS yfcI NC_008563.1 2527480 2528370 R hypothetical protein complement(2527480..2528370) Escherichia coli APEC O1 4493575 YP_853409.1 CDS hisP NC_008563.1 2528566 2529339 R histidine/lysine/arginine/ornithine transporter subunit complement(2528566..2529339) Escherichia coli APEC O1 4493576 YP_853410.1 CDS hisM NC_008563.1 2529347 2530063 R histidine/lysine/arginine/ornithine transporter subunit complement(2529347..2530063) Escherichia coli APEC O1 4493577 YP_853411.1 CDS hisQ NC_008563.1 2530060 2530746 R histidine transport system permease HisQ complement(2530060..2530746) Escherichia coli APEC O1 4493578 YP_853412.1 CDS hisJ NC_008563.1 2530836 2531618 R histidine/lysine/arginine/ornithine transporter subunit complement(2530836..2531618) Escherichia coli APEC O1 4493579 YP_853413.1 CDS argT NC_008563.1 2531839 2532621 R lysine/arginine/ornithine transporter subunit complement(2531839..2532621) Escherichia coli APEC O1 4493580 YP_853414.1 CDS ubiX NC_008563.1 2532887 2533456 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2532887..2533456) Escherichia coli APEC O1 4493581 YP_853415.1 CDS purF NC_008563.1 2533551 2535068 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2533551..2535068) Escherichia coli APEC O1 4493582 YP_853416.1 CDS cvpA NC_008563.1 2535105 2535593 R membrane protein required for colicin V production; colicin V production protein complement(2535105..2535593) Escherichia coli APEC O1 4493583 YP_853417.1 CDS dedD NC_008563.1 2536125 2536787 R hypothetical protein complement(2536125..2536787) Escherichia coli APEC O1 4493584 YP_853418.1 CDS folC NC_008563.1 2536777 2538045 R bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2536777..2538045) Escherichia coli APEC O1 4493585 YP_853419.2 CDS accD NC_008563.1 2538115 2539029 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2538115..2539029) Escherichia coli APEC O1 4493586 YP_853420.1 CDS APECO1_4247 NC_008563.1 2539185 2539844 R hypothetical protein complement(2539185..2539844) Escherichia coli APEC O1 4495788 YP_853421.1 CDS truA NC_008563.1 2539927 2540739 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2539927..2540739) Escherichia coli APEC O1 4495789 YP_853422.1 CDS usg NC_008563.1 2540739 2541752 R semialdehyde dehydrogenase complement(2540739..2541752) Escherichia coli APEC O1 4495790 YP_853423.1 CDS pdxB NC_008563.1 2541818 2542954 R erythronate-4-phosphate dehydrogenase complement(2541818..2542954) Escherichia coli APEC O1 4495791 YP_853424.1 CDS flk NC_008563.1 2543053 2544048 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2543053..2544048 Escherichia coli APEC O1 4495792 YP_853425.1 CDS yfcJ NC_008563.1 2544045 2545223 R hypothetical protein complement(2544045..2545223) Escherichia coli APEC O1 4495793 YP_853426.1 CDS fabB NC_008563.1 2545488 2546708 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2545488..2546708) Escherichia coli APEC O1 4495794 YP_853427.1 CDS mnmC NC_008563.1 2546867 2548873 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2546867..2548873 Escherichia coli APEC O1 4495795 YP_853428.1 CDS yfcL NC_008563.1 2548994 2549272 R hypothetical protein complement(2548994..2549272) Escherichia coli APEC O1 4495796 YP_853429.1 CDS yfcM NC_008563.1 2549306 2549854 R hypothetical protein complement(2549306..2549854) Escherichia coli APEC O1 4495797 YP_853430.1 CDS yfcA NC_008563.1 2549854 2550663 R hypothetical protein complement(2549854..2550663) Escherichia coli APEC O1 4495798 YP_853431.1 CDS mepA NC_008563.1 2550663 2551487 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2550663..2551487) Escherichia coli APEC O1 4495799 YP_853432.1 CDS aroC NC_008563.1 2551491 2552576 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2551491..2552576) Escherichia coli APEC O1 4495800 YP_853433.1 CDS prmB NC_008563.1 2552611 2553876 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2552611..2553876) Escherichia coli APEC O1 4495801 YP_853434.1 CDS yfcO NC_008563.1 2554580 2555422 R fimbrial adhesin YfcO complement(2554580..2555422) Escherichia coli APEC O1 4495802 YP_853435.1 CDS yfcP NC_008563.1 2555424 2555951 R Yfc fimbriae subunit YfcP complement(2555424..2555951) Escherichia coli APEC O1 4495803 YP_853436.1 CDS yfcQ NC_008563.1 2555948 2556427 R Yfc fimbriae subunit YfcQ complement(2555948..2556427) Escherichia coli APEC O1 4495804 YP_853437.1 CDS yfcR NC_008563.1 2556424 2556969 R hypothetical protein complement(2556424..2556969) Escherichia coli APEC O1 4495805 YP_853438.1 CDS yfcS NC_008563.1 2556944 2557696 R periplasmic chaperone YfcS complement(2556944..2557696) Escherichia coli APEC O1 4495806 YP_853439.1 CDS yfcU NC_008563.1 2557716 2560370 R pilus assembly protein; outer membrane usher YfcU complement(2557716..2560370) Escherichia coli APEC O1 4495593 YP_853440.1 CDS yfcV NC_008563.1 2560238 2560987 R Yfc fimbriae subunit YfcV complement(2560238..2560987) Escherichia coli APEC O1 4495594 YP_853441.1 CDS sixA NC_008563.1 2561553 2562038 R phosphohistidine phosphatase complement(2561553..2562038) Escherichia coli APEC O1 4495595 YP_853442.1 CDS fadJ NC_008563.1 2562241 2564385 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2562241..2564385) Escherichia coli APEC O1 4495596 YP_853443.1 CDS fadI NC_008563.1 2564385 2565695 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2564385..2565695) Escherichia coli APEC O1 4495597 YP_853444.1 CDS yfcZ NC_008563.1 2565876 2566184 R hypothetical protein complement(2565876..2566184) Escherichia coli APEC O1 4495598 YP_853445.1 CDS APECO1_4222 NC_008563.1 2566245 2566496 R hypothetical protein complement(2566245..2566496) Escherichia coli APEC O1 4495599 YP_853446.1 CDS fadL NC_008563.1 2566526 2567872 D long-chain fatty acid outer membrane transporter 2566526..2567872 Escherichia coli APEC O1 4495600 YP_853447.1 CDS vacJ NC_008563.1 2567930 2568685 R lipoprotein VacJ complement(2567930..2568685) Escherichia coli APEC O1 4495601 YP_853448.1 CDS yfdC NC_008563.1 2568979 2569911 D transporter 2568979..2569911 Escherichia coli APEC O1 4495602 YP_853449.1 CDS APECO1_4218 NC_008563.1 2570223 2571380 D phage integrase 2570223..2571380 Escherichia coli APEC O1 4495603 YP_853450.1 CDS APECO1_4217 NC_008563.1 2571620 2572543 R capsule O-acetyl transferase complement(2571620..2572543) Escherichia coli APEC O1 4495604 YP_853451.1 CDS sia NC_008563.1 2572697 2575642 R phage-associated; endo-alpha-sialidase complement(2572697..2575642) Escherichia coli APEC O1 4495605 YP_853452.1 CDS APECO1_4215 NC_008563.1 2575743 2576645 R phage-associated; antirepressor protein complement(2575743..2576645) Escherichia coli APEC O1 4495606 YP_853453.1 CDS APECO1_4214 NC_008563.1 2577393 2577929 D protease; hypothetical protein 2577393..2577929 Escherichia coli APEC O1 4495607 YP_853454.1 CDS APECO1_4213 NC_008563.1 2577978 2578427 R hypothetical protein complement(2577978..2578427) Escherichia coli APEC O1 4495608 YP_853455.1 CDS APECO1_4212 NC_008563.1 2578436 2579002 R hypothetical protein complement(2578436..2579002) Escherichia coli APEC O1 4495609 YP_853456.1 CDS APECO1_42112 NC_008563.1 2579199 2579528 D hypothetical protein 2579199..2579528 Escherichia coli APEC O1 4495610 YP_853457.1 CDS APECO1_4211 NC_008563.1 2579546 2581561 R hypothetical protein complement(2579546..2581561) Escherichia coli APEC O1 4495611 YP_853458.1 CDS APECO1_4210 NC_008563.1 2581558 2583009 R phage injection protein complement(2581558..2583009) Escherichia coli APEC O1 4495612 YP_853459.1 CDS APECO1_4209 NC_008563.1 2583020 2583712 R phage-associated; DNA transfer protein complement(2583020..2583712) Escherichia coli APEC O1 4494271 YP_853460.1 CDS APECO1_4208 NC_008563.1 2583715 2584170 R phage-associated; head assembly protein complement(2583715..2584170) Escherichia coli APEC O1 4494272 YP_853461.1 CDS APECO1_4207 NC_008563.1 2584170 2584871 R phage-associated; DNA stabilization protein complement(2584170..2584871) Escherichia coli APEC O1 4494273 YP_853462.1 CDS APECO1_4206 NC_008563.1 2584871 2586289 R phage-associated; DNA stabilization protein complement(2584871..2586289) Escherichia coli APEC O1 4494274 YP_853463.1 CDS APECO1_4205 NC_008563.1 2586299 2586760 R DNA stabilization protein complement(2586299..2586760) Escherichia coli APEC O1 4494275 YP_853464.1 CDS APECO1_4204 NC_008563.1 2586971 2588224 R phage coat protein; hypothetical protein complement(2586971..2588224) Escherichia coli APEC O1 4494276 YP_853465.1 CDS APECO1_4203 NC_008563.1 2588243 2589136 R phage scaffold protein complement(2588243..2589136) Escherichia coli APEC O1 4494277 YP_853466.1 CDS APECO1_4202 NC_008563.1 2589227 2591425 R phage portal protein complement(2589227..2591425) Escherichia coli APEC O1 4494278 YP_853467.1 CDS APECO1_4201 NC_008563.1 2591427 2592842 R phage terminase large subunit complement(2591427..2592842) Escherichia coli APEC O1 4494279 YP_853468.1 CDS APECO1_4200 NC_008563.1 2592839 2593279 R phage-associated; hypothetical protein complement(2592839..2593279) Escherichia coli APEC O1 4494280 YP_853469.1 CDS APECO1_4199 NC_008563.1 2593282 2593524 R phage-associated; hypothetical protein complement(2593282..2593524) Escherichia coli APEC O1 4494281 YP_853470.1 CDS APECO1_4198 NC_008563.1 2593752 2594363 R phage-associated; hypothetical protein complement(2593752..2594363) Escherichia coli APEC O1 4494282 YP_853471.1 CDS APECO1_4197 NC_008563.1 2594640 2595077 R phage-associated; hypothetical protein complement(2594640..2595077) Escherichia coli APEC O1 4494283 YP_853472.1 CDS APECO1_4196 NC_008563.1 2595074 2595550 R phage-associated; endolysin complement(2595074..2595550) Escherichia coli APEC O1 4494284 YP_853473.1 CDS APECO1_4195 NC_008563.1 2595534 2595857 R cell lysis protein; holin complement(2595534..2595857) Escherichia coli APEC O1 4494285 YP_853474.1 CDS APECO1_4194 NC_008563.1 2596454 2596972 R phage-associated; antitermination protein complement(2596454..2596972) Escherichia coli APEC O1 4494286 YP_853475.1 CDS APECO1_4193 NC_008563.1 2597154 2597516 R Holliday junction resolvase complement(2597154..2597516) Escherichia coli APEC O1 4494287 YP_853476.1 CDS APECO1_4192 NC_008563.1 2597513 2597803 R phage-associated; hypothetical protein complement(2597513..2597803) Escherichia coli APEC O1 4494288 YP_853477.1 CDS roi NC_008563.1 2597803 2598525 R phage-associated; DNA-binding protein Roi complement(2597803..2598525) Escherichia coli APEC O1 4494289 YP_853478.1 CDS APECO1_4190 NC_008563.1 2598687 2599112 R hypothetical protein complement(2598687..2599112) Escherichia coli APEC O1 4493527 YP_853479.1 CDS APECO1_4189 NC_008563.1 2599282 2599542 R phage-associated; hypothetical protein complement(2599282..2599542) Escherichia coli APEC O1 4493528 YP_853480.1 CDS APECO1_4188 NC_008563.1 2599892 2600206 R phage-associated; hypothetical protein complement(2599892..2600206) Escherichia coli APEC O1 4493529 YP_853481.1 CDS APECO1_4187 NC_008563.1 2600601 2601977 R phage-associated; replicative DNA helicase complement(2600601..2601977) Escherichia coli APEC O1 4493530 YP_853482.1 CDS APECO1_4186 NC_008563.1 2601974 2602921 R phage replication protein complement(2601974..2602921) Escherichia coli APEC O1 4493531 YP_853483.1 CDS APECO1_4185 NC_008563.1 2602924 2603196 R hypothetical protein complement(2602924..2603196) Escherichia coli APEC O1 4493532 YP_853484.1 CDS APECO1_4184 NC_008563.1 2603219 2603599 R phage-associated; hypothetical protein complement(2603219..2603599) Escherichia coli APEC O1 4493533 YP_853485.1 CDS APECO1_4183 NC_008563.1 2603887 2604537 D phage repressor protein 2603887..2604537 Escherichia coli APEC O1 4493534 YP_853486.1 CDS APECO1_4182 NC_008563.1 2604659 2604955 R hypothetical protein complement(2604659..2604955) Escherichia coli APEC O1 4493535 YP_853487.1 CDS APECO1_4180 NC_008563.1 2605060 2605359 D phage-associated; transcription antitermination protein 2605060..2605359 Escherichia coli APEC O1 4493536 YP_853488.1 CDS APECO1_4179 NC_008563.1 2605368 2605838 D phage-associated; hypothetical protein 2605368..2605838 Escherichia coli APEC O1 4493537 YP_853489.1 CDS APECO1_4178 NC_008563.1 2606460 2607065 D phage-associated; hypothetical protein 2606460..2607065 Escherichia coli APEC O1 4493538 YP_853490.1 CDS APECO1_4177 NC_008563.1 2607065 2607448 D phage-associated; hypothetical protein 2607065..2607448 Escherichia coli APEC O1 4493539 YP_853491.1 CDS APECO1_4176 NC_008563.1 2607472 2607768 D hypothetical protein 2607472..2607768 Escherichia coli APEC O1 4493540 YP_853492.1 CDS APECO1_4175 NC_008563.1 2607817 2608503 R hypothetical protein complement(2607817..2608503) Escherichia coli APEC O1 4493541 YP_853493.1 CDS APECO1_4174 NC_008563.1 2608679 2609251 D hypothetical protein 2608679..2609251 Escherichia coli APEC O1 4493542 YP_853494.1 CDS APECO1_4173 NC_008563.1 2609618 2609953 R hypothetical protein complement(2609618..2609953) Escherichia coli APEC O1 4493543 YP_853495.1 CDS dsdC NC_008563.1 2610499 2611434 R regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC complement(2610499..2611434) Escherichia coli APEC O1 4493544 YP_853496.1 CDS dsdX NC_008563.1 2611652 2612989 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2611652..2612989 Escherichia coli APEC O1 4493545 YP_853497.1 CDS dsdA NC_008563.1 2613007 2614335 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2613007..2614335 Escherichia coli APEC O1 4493546 YP_853498.1 CDS emrY NC_008563.1 2614443 2615981 R multidrug resistance protein Y complement(2614443..2615981) Escherichia coli APEC O1 4492484 YP_853499.1 CDS emrK NC_008563.1 2615981 2617036 R EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein complement(2615981..2617036) Escherichia coli APEC O1 4492485 YP_853500.1 CDS evgA NC_008563.1 2617560 2618174 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; EvgA family transcriptional regulator 2617560..2618174 Escherichia coli APEC O1 4492486 YP_853501.1 CDS evgS NC_008563.1 2618179 2621772 D EvgA family transcriptional regulator 2618179..2621772 Escherichia coli APEC O1 4492487 YP_853502.1 CDS yfdE NC_008563.1 2621828 2622973 R hypothetical protein complement(2621828..2622973) Escherichia coli APEC O1 4492488 YP_853503.1 CDS yfdV NC_008563.1 2623047 2623991 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(2623047..2623991) Escherichia coli APEC O1 4492489 YP_853504.1 CDS APECO1_4163 NC_008563.1 2624061 2625755 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(2624061..2625755) Escherichia coli APEC O1 4492490 YP_853505.1 CDS yfdW NC_008563.1 2625809 2627059 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2625809..2627059) Escherichia coli APEC O1 4492491 YP_853506.1 CDS yfdX NC_008563.1 2627571 2628206 R hypothetical protein complement(2627571..2628206) Escherichia coli APEC O1 4492492 YP_853507.1 CDS ypdI NC_008563.1 2628502 2628777 D lipoprotein involved in colanic acid biosynthesis 2628502..2628777 Escherichia coli APEC O1 4492493 YP_853508.1 CDS ddg NC_008563.1 2629449 2630369 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2629449..2630369 Escherichia coli APEC O1 4492494 YP_853509.1 CDS APECO1_4158 NC_008563.1 2630861 2632099 R aminotransferase complement(2630861..2632099) Escherichia coli APEC O1 4492495 YP_853510.1 CDS ypdA NC_008563.1 2632494 2634173 D YpdA, sensory kinase in two-component system with YpdB 2632494..2634173 Escherichia coli APEC O1 4492496 YP_853511.1 CDS ypdB NC_008563.1 2634263 2634925 D YpdB, response regulator in two-component system with YpdA 2634263..2634925 Escherichia coli APEC O1 4492497 YP_853512.1 CDS ypdC NC_008563.1 2634938 2635795 D DNA-binding protein 2634938..2635795 Escherichia coli APEC O1 4492498 YP_853513.1 CDS ypdD NC_008563.1 2635798 2638293 R phosphoenolpyruvate-protein phosphotransferase YpdD complement(2635798..2638293) Escherichia coli APEC O1 4492499 YP_853514.1 CDS ypdE NC_008563.1 2638318 2639355 R peptidase; metalloprotein; exoaminopeptidase complement(2638318..2639355) Escherichia coli APEC O1 4492500 YP_853515.1 CDS ypdF NC_008563.1 2639355 2640440 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2639355..2640440) Escherichia coli APEC O1 4492501 YP_853516.1 CDS ypdG NC_008563.1 2640456 2641703 R PTS system trannsporter subunit IIC complement(2640456..2641703) Escherichia coli APEC O1 4492502 YP_853517.1 CDS ypdH NC_008563.1 2641725 2642051 R PTS system IIB component YpdH complement(2641725..2642051) Escherichia coli APEC O1 4491676 YP_853518.1 CDS glk NC_008563.1 2642270 2643235 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2642270..2643235) Escherichia coli APEC O1 4491677 YP_853519.1 CDS yfeO NC_008563.1 2643439 2644695 D hypothetical protein 2643439..2644695 Escherichia coli APEC O1 4491678 YP_853520.1 CDS ypeC NC_008563.1 2644810 2645136 D hypothetical protein 2644810..2645136 Escherichia coli APEC O1 4491679 YP_853521.1 CDS mntH NC_008563.1 2645277 2646515 R manganese transport protein MntH complement(2645277..2646515) Escherichia coli APEC O1 4491680 YP_853522.1 CDS nupC NC_008563.1 2646851 2648053 D permease of transport system for 3 nucleosides 2646851..2648053 Escherichia coli APEC O1 4491681 YP_853523.1 CDS yfdA NC_008563.1 2648103 2650352 R ELA domain; outer membrane protein complement(2648103..2650352) Escherichia coli APEC O1 4491682 YP_853524.1 CDS yfdC NC_008563.1 2650910 2651269 D outer membrane protein 2650910..2651269 Escherichia coli APEC O1 4491683 YP_853525.1 CDS yfeD NC_008563.1 2651271 2651663 D DNA-binding transcriptional regulator 2651271..2651663 Escherichia coli APEC O1 4491684 YP_853526.1 CDS gltX NC_008563.1 2651714 2653129 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2651714..2653129) Escherichia coli APEC O1 4491685 YP_853527.1 CDS xapR NC_008563.1 2653896 2654795 R DNA-binding transcriptional activator XapR complement(2653896..2654795) Escherichia coli APEC O1 4491686 YP_853528.1 CDS xapB NC_008563.1 2655032 2656288 R xanthosine transporter complement(2655032..2656288) Escherichia coli APEC O1 4491687 YP_853529.1 CDS xapA NC_008563.1 2656349 2657182 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2656349..2657182) Escherichia coli APEC O1 4491688 YP_853530.1 CDS yfeN NC_008563.1 2657431 2658195 D sugar hydrolase; hypothetical protein 2657431..2658195 Escherichia coli APEC O1 4491689 YP_853531.1 CDS yfeH NC_008563.1 2659250 2660248 D cytochrome oxidase 2659250..2660248 Escherichia coli APEC O1 4491690 YP_853532.1 CDS ligA NC_008563.1 2660465 2662480 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2660465..2662480) Escherichia coli APEC O1 4491691 YP_853533.1 CDS zipA NC_008563.1 2662551 2663549 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2662551..2663549) Escherichia coli APEC O1 4491692 YP_853534.1 CDS cysZ NC_008563.1 2663779 2664540 D role in sulfur assimilation; sulfate transport protein CysZ 2663779..2664540 Escherichia coli APEC O1 4491693 YP_853535.1 CDS cysK NC_008563.1 2664725 2665696 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2664725..2665696 Escherichia coli APEC O1 4491694 YP_853536.1 CDS APECO1_4130 NC_008563.1 2666014 2666307 R hypothetical protein complement(2666014..2666307) Escherichia coli APEC O1 4491695 YP_853537.1 CDS ptsI NC_008563.1 2666382 2668109 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2666382..2668109 Escherichia coli APEC O1 4495731 YP_853538.1 CDS crr NC_008563.1 2668150 2668659 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2668150..2668659 Escherichia coli APEC O1 4495732 YP_853539.1 CDS pdxK NC_008563.1 2668702 2669553 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2668702..2669553) Escherichia coli APEC O1 4495733 YP_853540.1 CDS yfeK NC_008563.1 2669694 2670026 D hypothetical protein 2669694..2670026 Escherichia coli APEC O1 4495734 YP_853541.1 CDS cysM NC_008563.1 2670029 2670886 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2670029..2670886) Escherichia coli APEC O1 4495735 YP_853542.1 CDS cysA NC_008563.1 2671075 2672172 R sulfate/thiosulfate transporter subunit complement(2671075..2672172) Escherichia coli APEC O1 4495736 YP_853543.1 CDS cysW NC_008563.1 2672162 2673037 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2672162..2673037) Escherichia coli APEC O1 4495737 YP_853544.1 CDS cysT NC_008563.1 2673037 2673870 R sulfate/thiosulfate transporter subunit complement(2673037..2673870) Escherichia coli APEC O1 4495738 YP_853545.1 CDS cysP NC_008563.1 2673870 2674886 R thiosulfate transporter subunit complement(2673870..2674886) Escherichia coli APEC O1 4495739 YP_853546.1 CDS ucpA NC_008563.1 2675044 2675835 R short chain dehydrogenase complement(2675044..2675835) Escherichia coli APEC O1 4495740 YP_853547.1 CDS murQ NC_008563.1 2676115 2677011 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2676115..2677011 Escherichia coli APEC O1 4495741 YP_853548.1 CDS murP NC_008563.1 2677015 2678439 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2677015..2678439 Escherichia coli APEC O1 4495742 YP_853550.1 CDS yfdY NC_008563.1 2679612 2680187 R hypothetical protein complement(2679612..2680187) Escherichia coli APEC O1 4495744 YP_853551.1 CDS yfeZ NC_008563.1 2680248 2680697 R hypothetical protein complement(2680248..2680697) Escherichia coli APEC O1 4495745 YP_853552.1 CDS ypeA NC_008563.1 2680684 2681109 R acetyltransferase complement(2680684..2681109) Escherichia coli APEC O1 4495746 YP_853553.1 CDS amiA NC_008563.1 2681323 2682192 D N-acetylmuramoyl-l-alanine amidase I 2681323..2682192 Escherichia coli APEC O1 4495747 YP_853554.1 CDS hemF NC_008563.1 2682196 2683095 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2682196..2683095 Escherichia coli APEC O1 4495748 YP_853555.1 CDS yfeG NC_008563.1 2683101 2684153 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2683101..2684153) Escherichia coli APEC O1 4495749 YP_853556.1 CDS eutK NC_008563.1 2684199 2684699 R ethanolamine utilization protein EutK complement(2684199..2684699) Escherichia coli APEC O1 4494953 YP_853557.1 CDS eutL NC_008563.1 2684712 2685371 R ethanolamine utilization protein EutL complement(2684712..2685371) Escherichia coli APEC O1 4494954 YP_853558.1 CDS eutC NC_008563.1 2685381 2686268 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2685381..2686268) Escherichia coli APEC O1 4494955 YP_853559.1 CDS eutB NC_008563.1 2686289 2687650 R regulatory subunit of ethanolamine ammonia-lyase complement(2686289..2687650) Escherichia coli APEC O1 4494956 YP_853560.1 CDS eutA NC_008563.1 2687662 2689065 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2687662..2689065) Escherichia coli APEC O1 4494957 YP_853561.1 CDS eutH NC_008563.1 2689062 2690288 R ethanolamine utilization transport protein EutH complement(2689062..2690288) Escherichia coli APEC O1 4494958 YP_853562.1 CDS eutG NC_008563.1 2690505 2691719 R alcohol dehydrogenase in ethanolamine utilization complement(2690505..2691719) Escherichia coli APEC O1 4494959 YP_853563.1 CDS eutJ NC_008563.1 2691682 2692518 R chaperonin; ethanolamine utilization protein EutJ complement(2691682..2692518) Escherichia coli APEC O1 4494960 YP_853564.1 CDS eutE NC_008563.1 2692529 2693932 R ethanolamine utilization protein EutE acetaldehyde dehydrogenase complement(2692529..2693932) Escherichia coli APEC O1 4494961 YP_853565.1 CDS cchB NC_008563.1 2693944 2694231 R carboxysome structural protein, ethanolamine utilization complement(2693944..2694231) Escherichia coli APEC O1 4494962 YP_853566.1 CDS eutM NC_008563.1 2694338 2694673 R detox protein in ethanolamine utilization complement(2694338..2694673) Escherichia coli APEC O1 4494963 YP_853567.1 CDS eutD NC_008563.1 2694670 2695686 R ethanolamine utilization; in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2694670..2695686) Escherichia coli APEC O1 4494964 YP_853568.1 CDS eutT NC_008563.1 2695683 2696486 R cobalamin adenosyltransferase complement(2695683..2696486) Escherichia coli APEC O1 4494965 YP_853569.1 CDS eutQ NC_008563.1 2696483 2697184 R ethanolamine utilization protein EutQ complement(2696483..2697184) Escherichia coli APEC O1 4494966 YP_853570.1 CDS eutP NC_008563.1 2697159 2697638 R ethanolamine utilization protein EutP complement(2697159..2697638) Escherichia coli APEC O1 4494967 YP_853571.1 CDS eutS NC_008563.1 2697651 2697986 R ethanolamine utilization protein EutS complement(2697651..2697986) Escherichia coli APEC O1 4494968 YP_853572.1 CDS APECO1_4094 NC_008563.1 2698279 2700558 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2698279..2700558) Escherichia coli APEC O1 4494969 YP_853573.1 CDS talA NC_008563.1 2700847 2701797 D transaldolase A 2700847..2701797 Escherichia coli APEC O1 4494970 YP_853574.1 CDS tktB NC_008563.1 2701817 2703820 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2701817..2703820 Escherichia coli APEC O1 4494971 YP_853575.1 CDS ypfG NC_008563.1 2703897 2704940 R hypothetical protein complement(2703897..2704940) Escherichia coli APEC O1 4495289 YP_853576.1 CDS yffH NC_008563.1 2705066 2705641 R NUDIX hydrolase complement(2705066..2705641) Escherichia coli APEC O1 4495290 YP_853577.1 CDS aegA NC_008563.1 2705709 2707688 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(2705709..2707688) Escherichia coli APEC O1 4495291 YP_853578.1 CDS narQ NC_008563.1 2707879 2709594 D nitrate/nitrite sensor protein; nitrate/nitrite sensor protein NarQ 2707879..2709594 Escherichia coli APEC O1 4495292 YP_853579.1 CDS acrD NC_008563.1 2709758 2712871 D aminoglycoside/multidrug efflux system 2709758..2712871 Escherichia coli APEC O1 4495293 YP_853580.1 CDS yffB NC_008563.1 2713410 2713766 D hypothetical protein 2713410..2713766 Escherichia coli APEC O1 4495294 YP_853581.1 CDS dapE NC_008563.1 2713770 2714897 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2713770..2714897 Escherichia coli APEC O1 4495295 YP_853582.1 CDS ypfH NC_008563.1 2715206 2715928 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH complement(2715206..2715928) Escherichia coli APEC O1 4495296 YP_853583.1 CDS ypfI NC_008563.1 2715978 2717993 R hydrolase; hypothetical protein complement(2715978..2717993) Escherichia coli APEC O1 4495297 YP_853584.1 CDS ypfJ NC_008563.1 2718008 2718871 R metalloprotease; hypothetical protein complement(2718008..2718871) Escherichia coli APEC O1 4495298 YP_853585.1 CDS purC NC_008563.1 2719039 2719761 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2719039..2719761) Escherichia coli APEC O1 4495299 YP_853586.1 CDS nlpB NC_008563.1 2719965 2720999 R lipoprotein complement(2719965..2720999) Escherichia coli APEC O1 4495300 YP_853587.1 CDS dapA NC_008563.1 2721016 2721894 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2721016..2721894) Escherichia coli APEC O1 4495301 YP_853588.1 CDS gcvR NC_008563.1 2722067 2722612 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2722067..2722612 Escherichia coli APEC O1 4495302 YP_853589.1 CDS bcp NC_008563.1 2722612 2723082 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2722612..2723082 Escherichia coli APEC O1 4495303 YP_853590.1 CDS yfgO NC_008563.1 2723181 2724242 R permease PerM complement(2723181..2724242) Escherichia coli APEC O1 4495304 YP_853591.1 CDS yfgC NC_008563.1 2724455 2725918 D peptidase YfgC 2724455..2725918 Escherichia coli APEC O1 4495305 YP_853592.1 CDS yfgD NC_008563.1 2725939 2726298 D oxidoreductase YfgD 2725939..2726298 Escherichia coli APEC O1 4495306 YP_853593.1 CDS had NC_008563.1 2726436 2727182 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2726436..2727182) Escherichia coli APEC O1 4495307 YP_853594.1 CDS uraA NC_008563.1 2727232 2728521 R uracil transporter complement(2727232..2728521) Escherichia coli APEC O1 4495068 YP_853595.1 CDS upp NC_008563.1 2728607 2729233 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2728607..2729233) Escherichia coli APEC O1 4495069 YP_853596.1 CDS purM NC_008563.1 2729542 2730594 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2729542..2730594 Escherichia coli APEC O1 4495070 YP_853597.1 CDS purN NC_008563.1 2730594 2731232 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2730594..2731232 Escherichia coli APEC O1 4495071 YP_853598.1 CDS ppk NC_008563.1 2731404 2733470 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2731404..2733470 Escherichia coli APEC O1 4495072 YP_853599.1 CDS ppx NC_008563.1 2733475 2735016 D exopolyphosphatase 2733475..2735016 Escherichia coli APEC O1 4495073 YP_853600.1 CDS yfgF NC_008563.1 2735113 2737299 R inner membrane protein; hypothetical protein complement(2735113..2737299) Escherichia coli APEC O1 4495074 YP_853601.1 CDS APECO1_4065 NC_008563.1 2737516 2737782 R hypothetical protein complement(2737516..2737782) Escherichia coli APEC O1 4495075 YP_853602.1 CDS yfgH NC_008563.1 2738153 2738671 D outer membrane lipoprotein 2738153..2738671 Escherichia coli APEC O1 4495076 YP_853603.1 CDS yfgI NC_008563.1 2738687 2739226 D hypothetical protein 2738687..2739226 Escherichia coli APEC O1 4495077 YP_853604.1 CDS APECO1_4062 NC_008563.1 2739422 2739919 R phage lysis protein complement(2739422..2739919) Escherichia coli APEC O1 4495078 YP_853605.1 CDS APECO1_4061 NC_008563.1 2739916 2740545 R phage-associated; endolysin complement(2739916..2740545) Escherichia coli APEC O1 4495079 YP_853606.1 CDS APECO1_4060 NC_008563.1 2740535 2740843 R holin complement(2740535..2740843) Escherichia coli APEC O1 4495080 YP_853607.1 CDS APECO1_4059 NC_008563.1 2740830 2741234 R phage-associated; hypothetical protein complement(2740830..2741234) Escherichia coli APEC O1 4492738 YP_853608.1 CDS APECO1_4058 NC_008563.1 2741541 2744660 R similar to endo-N-acetylneuraminidase; hypothetical protein complement(2741541..2744660) Escherichia coli APEC O1 4492739 YP_853609.1 CDS APECO1_4057 NC_008563.1 2744733 2745113 D phage-associated; hypothetical protein 2744733..2745113 Escherichia coli APEC O1 4492740 YP_853610.1 CDS APECO1_4056 NC_008563.1 2745429 2746124 D phage-associated; anti-repressor protein 2745429..2746124 Escherichia coli APEC O1 4492741 YP_853611.1 CDS APECO1_4055 NC_008563.1 2747195 2747611 R hypothetical protein complement(2747195..2747611) Escherichia coli APEC O1 4492742 YP_853612.1 CDS APECO1_4054 NC_008563.1 2747795 2750269 R phage-associated; hypothetical protein complement(2747795..2750269) Escherichia coli APEC O1 4492743 YP_853613.1 CDS APECO1_4053 NC_008563.1 2750275 2752077 R phage-associated; hypothetical protein complement(2750275..2752077) Escherichia coli APEC O1 4492744 YP_853614.1 CDS APECO1_4052 NC_008563.1 2752074 2754587 R phage-associated; hypothetical protein complement(2752074..2754587) Escherichia coli APEC O1 4492745 YP_853615.1 CDS APECO1_4051 NC_008563.1 2754600 2755139 R phage-associated; hypothetical protein complement(2754600..2755139) Escherichia coli APEC O1 4492746 YP_853616.1 CDS APECO1_4050 NC_008563.1 2755139 2755603 R phage-associated; hypothetical protein complement(2755139..2755603) Escherichia coli APEC O1 4492747 YP_853617.1 CDS APECO1_4049 NC_008563.1 2755603 2758074 R phage-associated; hypothetical protein complement(2755603..2758074) Escherichia coli APEC O1 4492748 YP_853618.1 CDS APECO1_4048 NC_008563.1 2758074 2758679 R phage-associated; hypothetical protein complement(2758074..2758679) Escherichia coli APEC O1 4492749 YP_853619.1 CDS APECO1_4047 NC_008563.1 2758679 2759008 R phage-associated; hypothetical protein complement(2758679..2759008) Escherichia coli APEC O1 4492750 YP_853620.1 CDS APECO1_4046 NC_008563.1 2759053 2759397 R phage-associated; hypothetical protein complement(2759053..2759397) Escherichia coli APEC O1 4492751 YP_853621.1 CDS APECO1_4045 NC_008563.1 2759399 2759836 R phage-associated; hypothetical protein complement(2759399..2759836) Escherichia coli APEC O1 4492752 YP_853622.1 CDS APECO1_4044 NC_008563.1 2759888 2760880 R phage-associated; hypothetical protein complement(2759888..2760880) Escherichia coli APEC O1 4492753 YP_853623.1 CDS APECO1_4043 NC_008563.1 2760889 2761590 R phage-associated; hypothetical protein complement(2760889..2761590) Escherichia coli APEC O1 4492754 YP_853624.1 CDS APECO1_4042 NC_008563.1 2761587 2761883 R phage-associated; hypothetical protein complement(2761587..2761883) Escherichia coli APEC O1 4492755 YP_853625.1 CDS APECO1_4041 NC_008563.1 2761880 2763559 R phage-associated; tail protein complement(2761880..2763559) Escherichia coli APEC O1 4492756 YP_853627.1 CDS APECO1_4039 NC_008563.1 2764483 2764863 D phage-associated; hypothetical protein 2764483..2764863 Escherichia coli APEC O1 4495692 YP_853628.1 CDS APECO1_4038 NC_008563.1 2764954 2766429 R phage terminase, large subunit complement(2764954..2766429) Escherichia coli APEC O1 4495693 YP_853629.1 CDS APECO1_4037 NC_008563.1 2766426 2767031 R phage terminase small subunit complement(2766426..2767031) Escherichia coli APEC O1 4495694 YP_853630.1 CDS APECO1_4036 NC_008563.1 2767327 2767674 R phage-associated; hypothetical protein complement(2767327..2767674) Escherichia coli APEC O1 4495695 YP_853631.1 CDS APECO1_4035 NC_008563.1 2767780 2768310 R phage-associated; hypothetical protein complement(2767780..2768310) Escherichia coli APEC O1 4495696 YP_853632.1 CDS APECO1_4034 NC_008563.1 2768307 2768720 R phage-associated; hypothetical protein complement(2768307..2768720) Escherichia coli APEC O1 4495697 YP_853633.1 CDS APECO1_4033 NC_008563.1 2768886 2769203 R phage-associated; hypothetical protein complement(2768886..2769203) Escherichia coli APEC O1 4495698 YP_853634.1 CDS APECO1_4032 NC_008563.1 2769200 2769679 R phage-associated; hypothetical protein complement(2769200..2769679) Escherichia coli APEC O1 4495699 YP_853635.1 CDS APECO1_4031 NC_008563.1 2769741 2770085 R phage-associated; hypothetical protein complement(2769741..2770085) Escherichia coli APEC O1 4495700 YP_853636.1 CDS APECO1_4030 NC_008563.1 2770203 2770979 R hypothetical protein complement(2770203..2770979) Escherichia coli APEC O1 4495701 YP_853637.1 CDS APECO1_4029 NC_008563.1 2770951 2771799 R hypothetical protein complement(2770951..2771799) Escherichia coli APEC O1 4495702 YP_853638.1 CDS APECO1_4028 NC_008563.1 2772508 2773092 D repressor protein 2772508..2773092 Escherichia coli APEC O1 4495703 YP_853639.1 CDS APECO1_4027 NC_008563.1 2773386 2773700 D hypothetical protein 2773386..2773700 Escherichia coli APEC O1 4495704 YP_853640.1 CDS APECO1_4026 NC_008563.1 2773697 2774596 D phage-associated; hypothetical protein 2773697..2774596 Escherichia coli APEC O1 4495705 YP_853641.1 CDS recT NC_008563.1 2774606 2775628 D phage recombinase; recombination and repair protein RecT 2774606..2775628 Escherichia coli APEC O1 4495706 YP_853642.1 CDS APECO1_4024 NC_008563.1 2775678 2775926 D phage regulatory protein 2775678..2775926 Escherichia coli APEC O1 4495707 YP_853643.1 CDS APECO1_4023 NC_008563.1 2776036 2776335 D hypothetical protein 2776036..2776335 Escherichia coli APEC O1 4495708 YP_853644.1 CDS APECO1_4022 NC_008563.1 2776328 2776978 D phage-associated; adenine methylase 2776328..2776978 Escherichia coli APEC O1 4495709 YP_853645.1 CDS APECO1_4021 NC_008563.1 2776855 2777634 D diadenosine tetraphosphatase and related serine/threonine protein phosphatases COG; hypothetical protein 2776855..2777634 Escherichia coli APEC O1 4495710 YP_853646.1 CDS APECO1_4020 NC_008563.1 2777637 2778893 R phage-associated; integrase-like protein complement(2777637..2778893) Escherichia coli APEC O1 4494219 YP_853647.1 CDS guaA NC_008563.1 2779086 2780663 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2779086..2780663) Escherichia coli APEC O1 4494220 YP_853648.1 CDS guaB NC_008563.1 2780732 2782267 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2780732..2782267) Escherichia coli APEC O1 4494221 YP_853649.1 CDS xseA NC_008563.1 2782360 2783736 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2782360..2783736 Escherichia coli APEC O1 4494222 YP_853650.1 CDS APECO1_4016 NC_008563.1 2783805 2791856 R RatA-like protein complement(2783805..2791856) Escherichia coli APEC O1 4494223 YP_853651.1 CDS sinI NC_008563.1 2791977 2792954 R SinI-like protein complement(2791977..2792954) Escherichia coli APEC O1 4494224 YP_853652.1 CDS sinH NC_008563.1 2793009 2795240 R intimin/invasin complement(2793009..2795240) Escherichia coli APEC O1 4494225 YP_853653.1 CDS engA NC_008563.1 2795727 2797238 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2795727..2797238) Escherichia coli APEC O1 4494226 YP_853654.1 CDS yfgL NC_008563.1 2797317 2798495 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2797317..2798495) Escherichia coli APEC O1 4494227 YP_853655.1 CDS yfgM NC_008563.1 2798506 2799126 R hypothetical protein complement(2798506..2799126) Escherichia coli APEC O1 4494228 YP_853656.1 CDS hisS NC_008563.1 2799144 2800418 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2799144..2800418) Escherichia coli APEC O1 4494229 YP_853657.1 CDS ispG NC_008563.1 2800529 2801647 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2800529..2801647) Escherichia coli APEC O1 4494230 YP_853658.1 CDS yfgA NC_008563.1 2801674 2802681 R cytoskeletal protein RodZ complement(2801674..2802681) Escherichia coli APEC O1 4494231 YP_853659.1 CDS yfgB NC_008563.1 2802966 2804120 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2802966..2804120) Escherichia coli APEC O1 4494232 YP_853660.1 CDS ndk NC_008563.1 2804270 2804701 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2804270..2804701) Escherichia coli APEC O1 4494233 YP_853661.1 CDS pbpC NC_008563.1 2804850 2807162 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2804850..2807162) Escherichia coli APEC O1 4494234 YP_853662.1 CDS yfhM NC_008563.1 2807163 2812124 R lipoprotein YfhM complement(2807163..2812124) Escherichia coli APEC O1 4494235 YP_853663.1 CDS sseA NC_008563.1 2812172 2813176 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2812172..2813176 Escherichia coli APEC O1 4494236 YP_853664.1 CDS sseB NC_008563.1 2813669 2814454 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2813669..2814454) Escherichia coli APEC O1 4494237 YP_853665.1 CDS pepB NC_008563.1 2814587 2815870 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(2814587..2815870) Escherichia coli APEC O1 4492348 YP_853666.1 CDS fdx NC_008563.1 2816141 2816476 R [2Fe-2S] ferredoxin complement(2816141..2816476) Escherichia coli APEC O1 4492349 YP_853667.1 CDS hscA NC_008563.1 2816478 2818382 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2816478..2818382) Escherichia coli APEC O1 4492350 YP_853668.1 CDS hscB NC_008563.1 2818345 2818860 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2818345..2818860) Escherichia coli APEC O1 4492351 YP_853669.1 CDS iscA NC_008563.1 2818956 2819279 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2818956..2819279) Escherichia coli APEC O1 4492352 YP_853670.1 CDS iscU NC_008563.1 2819296 2819682 R scaffold protein complement(2819296..2819682) Escherichia coli APEC O1 4492353 YP_853671.1 CDS iscS NC_008563.1 2819710 2820948 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2819710..2820948) Escherichia coli APEC O1 4492354 YP_853672.1 CDS iscR NC_008563.1 2821036 2821524 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2821036..2821524) Escherichia coli APEC O1 4492355 YP_853673.1 CDS yfhQ NC_008563.1 2821794 2822534 R methyltransferase complement(2821794..2822534) Escherichia coli APEC O1 4492356 YP_853674.1 CDS suhB NC_008563.1 2822653 2823456 D inositol monophosphatase 2822653..2823456 Escherichia coli APEC O1 4492357 YP_853675.1 CDS yfhR NC_008563.1 2823574 2824455 D peptidase 2823574..2824455 Escherichia coli APEC O1 4492358 YP_853676.1 CDS csiE NC_008563.1 2824625 2825926 D stationary phase inducible protein CsiE 2824625..2825926 Escherichia coli APEC O1 4492359 YP_853677.1 CDS hcaT NC_008563.1 2825918 2827057 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(2825918..2827057) Escherichia coli APEC O1 4492360 YP_853678.1 CDS yphA NC_008563.1 2827381 2827848 D hypothetical protein 2827381..2827848 Escherichia coli APEC O1 4492361 YP_853679.1 CDS yphB NC_008563.1 2828008 2828880 R hypothetical protein complement(2828008..2828880) Escherichia coli APEC O1 4492362 YP_853680.1 CDS yphC NC_008563.1 2828892 2829986 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(2828892..2829986) Escherichia coli APEC O1 4492363 YP_853681.1 CDS yphD NC_008563.1 2830019 2831017 R sugar ABC transporter permease complement(2830019..2831017) Escherichia coli APEC O1 4492364 YP_853682.1 CDS yphE NC_008563.1 2831042 2832553 R sugar ABC transporter ATP-binding protein complement(2831042..2832553) Escherichia coli APEC O1 4492365 YP_853683.1 CDS yphF NC_008563.1 2832576 2833559 R sugar ABC transporter periplasmic component YphF complement(2832576..2833559) Escherichia coli APEC O1 4492366 YP_853684.1 CDS yphG NC_008563.1 2833656 2836937 R TPR repeat domain; hypothetical protein complement(2833656..2836937) Escherichia coli APEC O1 4492367 YP_853685.1 CDS ychA NC_008563.1 2837055 2838248 D transcriptional regulator YchA 2837055..2838248 Escherichia coli APEC O1 4492368 YP_853686.1 CDS glyA NC_008563.1 2838312 2839571 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2838312..2839571) Escherichia coli APEC O1 4492369 YP_853687.1 CDS hmpA NC_008563.1 2839894 2841084 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2839894..2841084 Escherichia coli APEC O1 4492370 YP_853688.1 CDS glnB NC_008563.1 2841129 2841467 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2841129..2841467) Escherichia coli APEC O1 4492371 YP_853689.1 CDS yfhA NC_008563.1 2841528 2842901 R two component system DNA-binding response regulator complement(2841528..2842901) Escherichia coli APEC O1 4492372 YP_853690.1 CDS yfhG NC_008563.1 2842852 2843571 R hypothetical protein complement(2842852..2843571) Escherichia coli APEC O1 4492373 YP_853691.1 CDS yfhK NC_008563.1 2843730 2845112 R sensor-like histidine kinase YfhK complement(2843730..2845112) Escherichia coli APEC O1 4492374 YP_853692.1 CDS purL NC_008563.1 2845733 2849620 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2845733..2849620) Escherichia coli APEC O1 4492375 YP_853693.1 CDS yfhD NC_008563.1 2850019 2851437 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2850019..2851437 Escherichia coli APEC O1 4492376 YP_853694.1 CDS tadA NC_008563.1 2851434 2851970 R tRNA-specific adenosine deaminase complement(2851434..2851970) Escherichia coli APEC O1 4492377 YP_853695.1 CDS yfhH NC_008563.1 2852767 2853687 D DNA-binding transcriptional regulator 2852767..2853687 Escherichia coli APEC O1 4492378 YP_853696.1 CDS yfhL NC_008563.1 2853743 2854003 D 4Fe-4S binding protein 2853743..2854003 Escherichia coli APEC O1 4492379 YP_853697.1 CDS acpS NC_008563.1 2854698 2855078 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2854698..2855078) Escherichia coli APEC O1 4492380 YP_853698.1 CDS pdxJ NC_008563.1 2855078 2855824 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2855078..2855824) Escherichia coli APEC O1 4492381 YP_853699.1 CDS recO NC_008563.1 2855821 2856549 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2855821..2856549) Escherichia coli APEC O1 4492382 YP_853700.1 CDS era NC_008563.1 2856561 2857466 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2856561..2857466) Escherichia coli APEC O1 4492383 YP_853701.1 CDS rnc NC_008563.1 2857463 2858143 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2857463..2858143) Escherichia coli APEC O1 4492384 YP_853702.1 CDS lepB NC_008563.1 2858410 2859384 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2858410..2859384) Escherichia coli APEC O1 4492385 YP_853703.1 CDS lepA NC_008563.1 2859400 2861199 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2859400..2861199) Escherichia coli APEC O1 4492386 YP_853704.1 CDS rseC NC_008563.1 2861397 2861876 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2861397..2861876) Escherichia coli APEC O1 4495425 YP_853705.1 CDS rseB NC_008563.1 2861873 2862829 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2861873..2862829) Escherichia coli APEC O1 4495426 YP_853706.1 CDS rseA NC_008563.1 2862829 2863479 R anti-RNA polymerase sigma factor SigE complement(2862829..2863479) Escherichia coli APEC O1 4495427 YP_853707.1 CDS rpoE NC_008563.1 2863512 2864120 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2863512..2864120) Escherichia coli APEC O1 4495428 YP_853708.1 CDS nadB NC_008563.1 2864495 2866117 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2864495..2866117 Escherichia coli APEC O1 4495429 YP_853709.1 CDS yfiC NC_008563.1 2866102 2866959 R hypothetical protein complement(2866102..2866959) Escherichia coli APEC O1 4495430 YP_853710.1 CDS srmB NC_008563.1 2866971 2868305 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2866971..2868305 Escherichia coli APEC O1 4495431 YP_853711.1 CDS yfiE NC_008563.1 2868338 2869264 R transcriptional regulator YfiE complement(2868338..2869264) Escherichia coli APEC O1 4495432 YP_853712.1 CDS yfiK NC_008563.1 2869322 2869909 D neutral amino acid efflux protein 2869322..2869909 Escherichia coli APEC O1 4495433 YP_853713.1 CDS yfiD NC_008563.1 2869965 2870348 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2869965..2870348) Escherichia coli APEC O1 4495434 YP_853714.1 CDS ung NC_008563.1 2870653 2871342 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2870653..2871342 Escherichia coli APEC O1 4495435 YP_853715.1 CDS yfiF NC_008563.1 2871390 2871761 R tRNA/rRNA methyltransferase YfiF complement(2871390..2871761) Escherichia coli APEC O1 4495436 YP_853716.1 CDS yfiF NC_008563.1 2871967 2872569 D tRNA/rRNA methyltransferase YfiF 2871967..2872569 Escherichia coli APEC O1 4495437 YP_853717.1 CDS trxC NC_008563.1 2872638 2873057 D thioredoxin 2872638..2873057 Escherichia coli APEC O1 4495438 YP_853718.1 CDS yfiP NC_008563.1 2873102 2873824 D hypothetical protein 2873102..2873824 Escherichia coli APEC O1 4495439 YP_853719.1 CDS yfiQ NC_008563.1 2873856 2876516 D acyl-CoA synthetase (NDP forming) 2873856..2876516 Escherichia coli APEC O1 4495440 YP_853720.1 CDS pssA NC_008563.1 2876627 2877985 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2876627..2877985 Escherichia coli APEC O1 4495441 YP_853721.1 CDS yfiM NC_008563.1 2878082 2878354 D hypothetical protein 2878082..2878354 Escherichia coli APEC O1 4495442 YP_853722.1 CDS kgtP NC_008563.1 2878351 2879742 R alpha-ketoglutarate transporter complement(2878351..2879742) Escherichia coli APEC O1 4495443 YP_853723.1 CDS APECO1_3944 NC_008563.1 2879972 2880307 R ISEc12 ATP-binding protein complement(2879972..2880307) Escherichia coli APEC O1 4495444 YP_853724.1 CDS APECO1_3943 NC_008563.1 2880735 2882276 R transposase for ISEc12 complement(2880735..2882276) Escherichia coli APEC O1 4493458 YP_853725.1 CDS APECO1_3942 NC_008563.1 2882841 2883272 D hypothetical protein 2882841..2883272 Escherichia coli APEC O1 4493459 YP_853726.1 CDS APECO1_3941 NC_008563.1 2883791 2884513 R transposase subunit complement(2883791..2884513) Escherichia coli APEC O1 4493460 YP_853727.1 CDS APECO1_3940 NC_008563.1 2884618 2884941 R transposase subunit complement(2884618..2884941) Escherichia coli APEC O1 4493461 YP_853729.1 CDS clpB NC_008563.1 2890825 2893410 R chaperone; protein disaggregation chaperone complement(2890825..2893410) Escherichia coli APEC O1 4493463 YP_853730.1 CDS yfiH NC_008563.1 2893528 2894259 R hypothetical protein complement(2893528..2894259) Escherichia coli APEC O1 4493464 YP_853731.1 CDS rluD NC_008563.1 2894256 2895236 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2894256..2895236) Escherichia coli APEC O1 4493465 YP_853732.1 CDS yfiO NC_008563.1 2895371 2896108 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2895371..2896108 Escherichia coli APEC O1 4493466 YP_853733.1 CDS pheA NC_008563.1 2896969 2898129 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2896969..2898129 Escherichia coli APEC O1 4493467 YP_853734.1 CDS tyrA NC_008563.1 2898172 2899293 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2898172..2899293) Escherichia coli APEC O1 4493468 YP_853735.2 CDS aroF NC_008563.1 2899304 2900374 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2899304..2900374) Escherichia coli APEC O1 4493469 YP_853736.1 CDS yfiL NC_008563.1 2900584 2900949 D hypothetical protein 2900584..2900949 Escherichia coli APEC O1 4493470 YP_853737.1 CDS yfiR NC_008563.1 2901098 2901616 D hypothetical protein 2901098..2901616 Escherichia coli APEC O1 4493471 YP_853738.1 CDS yfiN NC_008563.1 2901606 2902832 D hypothetical protein 2901606..2902832 Escherichia coli APEC O1 4493472 YP_853739.1 CDS yfiB NC_008563.1 2902848 2903330 D outer membrane lipoprotein 2902848..2903330 Escherichia coli APEC O1 4493473 YP_853740.1 CDS rplS NC_008563.1 2903407 2903754 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2903407..2903754) Escherichia coli APEC O1 4493474 YP_853741.1 CDS trmD NC_008563.1 2903796 2904128 R tRNA (guanine-1-)-methyltransferase complement(2903796..2904128) Escherichia coli APEC O1 4493475 YP_853742.1 CDS trmD NC_008563.1 2904206 2904565 R tRNA (guanine-1-)-methyltransferase complement(2904206..2904565) Escherichia coli APEC O1 4493476 YP_853743.1 CDS rimM NC_008563.1 2904596 2905147 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2904596..2905147) Escherichia coli APEC O1 4495386 YP_853744.1 CDS rpsP NC_008563.1 2905163 2905471 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2905163..2905471) Escherichia coli APEC O1 4495387 YP_853745.1 CDS ffh NC_008563.1 2905548 2906909 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2905548..2906909) Escherichia coli APEC O1 4495388 YP_853746.1 CDS ypjD NC_008563.1 2907001 2907867 D inner membrane protein; hypothetical protein 2907001..2907867 Escherichia coli APEC O1 4495389 YP_853747.1 CDS APECO1_3921 NC_008563.1 2907933 2909174 D hypothetical protein 2907933..2909174 Escherichia coli APEC O1 4495390 YP_853748.1 CDS APECO1_3920 NC_008563.1 2909196 2909948 D hypothetical protein 2909196..2909948 Escherichia coli APEC O1 4495391 YP_853749.1 CDS ppnK NC_008563.1 2909945 2910823 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2909945..2910823 Escherichia coli APEC O1 4495392 YP_853750.1 CDS recN NC_008563.1 2910909 2912570 D recombination and repair protein 2910909..2912570 Escherichia coli APEC O1 4495393 YP_853751.1 CDS smpA NC_008563.1 2912719 2913060 D hypothetical protein 2912719..2913060 Escherichia coli APEC O1 4495394 YP_853752.1 CDS yfjG NC_008563.1 2913402 2913878 R hypothetical protein complement(2913402..2913878) Escherichia coli APEC O1 4495395 YP_853753.1 CDS smpB NC_008563.1 2914010 2914492 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2914010..2914492 Escherichia coli APEC O1 4495396 YP_853754.1 CDS APECO1_3914 NC_008563.1 2915071 2915325 R hypothetical protein complement(2915071..2915325) Escherichia coli APEC O1 4495397 YP_853755.1 CDS APECO1_3913 NC_008563.1 2915649 2916437 D hypothetical protein 2915649..2916437 Escherichia coli APEC O1 4495398 YP_853756.1 CDS APECO1_39122 NC_008563.1 2916525 2916818 R hypothetical protein complement(2916525..2916818) Escherichia coli APEC O1 4495399 YP_853757.1 CDS APECO1_3912 NC_008563.1 2917029 2917802 R hypothetical protein complement(2917029..2917802) Escherichia coli APEC O1 4495400 YP_853758.1 CDS APECO1_3911 NC_008563.1 2918794 2920608 D hypothetical protein 2918794..2920608 Escherichia coli APEC O1 4495401 YP_853759.1 CDS APECO1_3910 NC_008563.1 2920995 2921489 D tail fiber protein 2920995..2921489 Escherichia coli APEC O1 4495402 YP_853760.1 CDS APECO1_3909 NC_008563.1 2921489 2922091 D tail fiber assembly protein 2921489..2922091 Escherichia coli APEC O1 4495403 YP_853761.1 CDS APECO1_3908 NC_008563.1 2922063 2922506 R phage-associated; hypothetical protein complement(2922063..2922506) Escherichia coli APEC O1 4495404 YP_853762.1 CDS APECO1_3907 NC_008563.1 2923256 2923840 R phage-associated; hypothetical protein complement(2923256..2923840) Escherichia coli APEC O1 4495405 YP_853763.1 CDS APECO1_3906 NC_008563.1 2923831 2924889 R bacteriophage V tail protein complement(2923831..2924889) Escherichia coli APEC O1 4494180 YP_853764.1 CDS APECO1_3905 NC_008563.1 2924876 2925304 R bacteriophage V tail protein complement(2924876..2925304) Escherichia coli APEC O1 4494181 YP_853765.1 CDS APECO1_3904 NC_008563.1 2925301 2925849 R bacteriophage V tail protein complement(2925301..2925849) Escherichia coli APEC O1 4494182 YP_853766.1 CDS APECO1_3903 NC_008563.1 2925849 2926928 R tail protein complement(2925849..2926928) Escherichia coli APEC O1 4494183 YP_853767.1 CDS APECO1_3902 NC_008563.1 2926925 2928295 R bacteriophage V tail/DNA circulation protein complement(2926925..2928295) Escherichia coli APEC O1 4494184 YP_853768.1 CDS APECO1_3901 NC_008563.1 2928314 2930149 R bacteriophage V tail protein complement(2928314..2930149) Escherichia coli APEC O1 4494185 YP_853769.1 CDS APECO1_3900 NC_008563.1 2930148 2930441 D hypothetical protein 2930148..2930441 Escherichia coli APEC O1 4494186 YP_853770.1 CDS APECO1_3899 NC_008563.1 2930560 2930916 R phage-associated; hypothetical protein complement(2930560..2930916) Escherichia coli APEC O1 4494187 YP_853771.1 CDS APECO1_3898 NC_008563.1 2930916 2932412 R bacteriophage V tail sheath pro complement(2930916..2932412) Escherichia coli APEC O1 4494188 YP_853772.1 CDS APECO1_3897 NC_008563.1 2932575 2933135 R phage-associated; hypothetical protein complement(2932575..2933135) Escherichia coli APEC O1 4494189 YP_853773.1 CDS APECO1_3896 NC_008563.1 2933132 2933638 R phage-associated; hypothetical protein complement(2933132..2933638) Escherichia coli APEC O1 4494190 YP_853774.1 CDS APECO1_3895 NC_008563.1 2933613 2934023 R bacteriophage head tail adaptor complement(2933613..2934023) Escherichia coli APEC O1 4494191 YP_853775.1 CDS APECO1_3894 NC_008563.1 2934020 2934343 R phage-associated; hypothetical protein complement(2934020..2934343) Escherichia coli APEC O1 4494192 YP_853776.1 CDS APECO1_3893 NC_008563.1 2934596 2935801 R major capsid protein complement(2934596..2935801) Escherichia coli APEC O1 4494193 YP_853777.1 CDS APECO1_3892 NC_008563.1 2935816 2936502 R pro-head protease complement(2935816..2936502) Escherichia coli APEC O1 4494194 YP_853778.1 CDS APECO1_3891 NC_008563.1 2936444 2937559 R phage portal protein complement(2936444..2937559) Escherichia coli APEC O1 4494195 YP_853779.1 CDS APECO1_3890 NC_008563.1 2937879 2939612 R bacteriophage V large terminase subunit complement(2937879..2939612) Escherichia coli APEC O1 4494196 YP_853780.1 CDS APECO1_3889 NC_008563.1 2939609 2940103 R bacteriophage V small terminase subunit complement(2939609..2940103) Escherichia coli APEC O1 4494197 YP_853781.1 CDS APECO1_3888 NC_008563.1 2940229 2940579 R phage endonuclease complement(2940229..2940579) Escherichia coli APEC O1 4494198 YP_853782.1 CDS APECO1_3887 NC_008563.1 2941550 2941987 R phage lysis protein complement(2941550..2941987) Escherichia coli APEC O1 4491304 YP_853783.1 CDS APECO1_3886 NC_008563.1 2941984 2942460 R phage-associated; muramidase complement(2941984..2942460) Escherichia coli APEC O1 4491305 YP_853784.1 CDS APECO1_3885 NC_008563.1 2942447 2942851 R phage-associated; hypothetical protein complement(2942447..2942851) Escherichia coli APEC O1 4491306 YP_853785.1 CDS APECO1_3884 NC_008563.1 2942904 2943239 R phage-associated; hypothetical protein complement(2942904..2943239) Escherichia coli APEC O1 4491307 YP_853786.1 CDS APECO1_3883 NC_008563.1 2943425 2944177 R phage-associated; Qin-like prophage; antitermination protein Q complement(2943425..2944177) Escherichia coli APEC O1 4491308 YP_853787.1 CDS APECO1_3882 NC_008563.1 2944191 2945144 R phage-associated; hypothetical protein complement(2944191..2945144) Escherichia coli APEC O1 4491310 YP_853788.1 CDS APECO1_3881 NC_008563.1 2945188 2945985 R phage-associated; hypothetical protein complement(2945188..2945985) Escherichia coli APEC O1 4491311 YP_853789.1 CDS APECO1_3880 NC_008563.1 2946005 2946394 R phage-associated; bacteriophage V crossover junction endodeoxyribonuclease complement(2946005..2946394) Escherichia coli APEC O1 4491313 YP_853790.1 CDS APECO1_3879 NC_008563.1 2946391 2946717 R phage-associated; hypothetical protein complement(2946391..2946717) Escherichia coli APEC O1 4491314 YP_853791.1 CDS APECO1_3878 NC_008563.1 2946714 2947367 R phage-associated; DNA adenine methylase complement(2946714..2947367) Escherichia coli APEC O1 4491315 YP_853792.1 CDS APECO1_3877 NC_008563.1 2947367 2947855 R phage-associated; hypothetical protein complement(2947367..2947855) Escherichia coli APEC O1 4491316 YP_853793.1 CDS APECO1_3876 NC_008563.1 2947858 2948799 R phage-associated; hypothetical protein complement(2947858..2948799) Escherichia coli APEC O1 4491318 YP_853794.1 CDS ymfM NC_008563.1 2948809 2949147 R phage-associated; hypothetical protein complement(2948809..2949147) Escherichia coli APEC O1 4491319 YP_853795.1 CDS ymfL NC_008563.1 2949144 2949707 R phage-associated; e14 prophage; DNA-binding transcriptional regulator complement(2949144..2949707) Escherichia coli APEC O1 4491320 YP_853796.1 CDS APECO1_3873 NC_008563.1 2949739 2950044 R phage-associated; hypothetical protein complement(2949739..2950044) Escherichia coli APEC O1 4491321 YP_853797.1 CDS APECO1_3872 NC_008563.1 2950030 2950704 D phage-associated; phage repressor 2950030..2950704 Escherichia coli APEC O1 4491322 YP_853798.1 CDS APECO1_3871 NC_008563.1 2950907 2951419 R hypothetical protein complement(2950907..2951419) Escherichia coli APEC O1 4491323 YP_853799.1 CDS APECO1_3870 NC_008563.1 2951570 2952250 D hypothetical protein 2951570..2952250 Escherichia coli APEC O1 4492445 YP_853800.1 CDS yfdQ NC_008563.1 2952316 2953140 D hypothetical protein 2952316..2953140 Escherichia coli APEC O1 4492446 YP_853801.1 CDS yfdR NC_008563.1 2953268 2953792 D hypothetical protein 2953268..2953792 Escherichia coli APEC O1 4492447 YP_853802.1 CDS APECO1_3867 NC_008563.1 2953901 2954767 D hypothetical protein 2953901..2954767 Escherichia coli APEC O1 4492448 YP_853803.1 CDS APECO1_3866 NC_008563.1 2954976 2956148 D hypothetical protein 2954976..2956148 Escherichia coli APEC O1 4492449 YP_853804.1 CDS APECO1_3865 NC_008563.1 2956140 2956739 R hypothetical protein complement(2956140..2956739) Escherichia coli APEC O1 4492450 YP_853805.1 CDS APECO1_3864 NC_008563.1 2956768 2957094 R hypothetical protein complement(2956768..2957094) Escherichia coli APEC O1 4492451 YP_853806.1 CDS APECO1_3863 NC_008563.1 2957099 2958010 R hypothetical protein complement(2957099..2958010) Escherichia coli APEC O1 4492452 YP_853807.1 CDS APECO1_3862 NC_008563.1 2957976 2958239 D hypothetical protein 2957976..2958239 Escherichia coli APEC O1 4492453 YP_853808.1 CDS ygaT NC_008563.1 2958871 2959848 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2958871..2959848 Escherichia coli APEC O1 4492454 YP_853809.1 CDS ygaF NC_008563.1 2959868 2961136 D dehydrogenase; catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2959868..2961136 Escherichia coli APEC O1 4492455 YP_853810.1 CDS gabD NC_008563.1 2961159 2962607 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2961159..2962607 Escherichia coli APEC O1 4492456 YP_853811.1 CDS gabT NC_008563.1 2962615 2963901 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2962615..2963901 Escherichia coli APEC O1 4492457 YP_853812.1 CDS gabP NC_008563.1 2964076 2965539 D gamma-aminobutyrate transporter 2964076..2965539 Escherichia coli APEC O1 4492458 YP_853813.1 CDS ygaE NC_008563.1 2965542 2966222 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2965542..2966222 Escherichia coli APEC O1 4492459 YP_853814.1 CDS ygaU NC_008563.1 2966223 2966672 R LysM domain/BON superfamily protein complement(2966223..2966672) Escherichia coli APEC O1 4492460 YP_853815.1 CDS ygaV NC_008563.1 2967097 2967396 D DNA-binding transcriptional regulator 2967097..2967396 Escherichia coli APEC O1 4492461 YP_853816.1 CDS ygaP NC_008563.1 2967406 2967930 D hypothetical protein 2967406..2967930 Escherichia coli APEC O1 4492462 YP_853817.1 CDS stpA NC_008563.1 2967977 2968381 R DNA binding protein complement(2967977..2968381) Escherichia coli APEC O1 4492463 YP_853821.1 CDS ygaW NC_008563.1 2969048 2969497 D hypothetical protein 2969048..2969497 Escherichia coli APEC O1 4493086 YP_853831.1 CDS ygaC NC_008563.1 2969534 2969878 R hypothetical protein complement(2969534..2969878) Escherichia coli APEC O1 4493087 YP_853835.1 CDS ygaM NC_008563.1 2970018 2970359 D hypothetical protein 2970018..2970359 Escherichia coli APEC O1 4493088 YP_853846.1 CDS APECO1_3849 NC_008563.1 2970416 2971750 R GntR family transcriptional regulator complement(2970416..2971750) Escherichia coli APEC O1 4493089 YP_853848.1 CDS APECO1_3848 NC_008563.1 2971838 2972269 D hypothetical protein 2971838..2972269 Escherichia coli APEC O1 4493090 YP_853850.1 CDS nrdI NC_008563.1 2972720 2973130 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2972720..2973130 Escherichia coli APEC O1 4493091 YP_853851.1 CDS nrdE NC_008563.1 2973142 2975247 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2973142..2975247 Escherichia coli APEC O1 4493092 YP_853853.1 CDS nrdF NC_008563.1 2975257 2976216 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2975257..2976216 Escherichia coli APEC O1 4493093 YP_853854.1 CDS proV NC_008563.1 2976572 2977774 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2976572..2977774 Escherichia coli APEC O1 4493094 YP_853857.1 CDS proW NC_008563.1 2977767 2978831 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2977767..2978831 Escherichia coli APEC O1 4493095 YP_853858.1 CDS proX NC_008563.1 2978889 2979881 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2978889..2979881 Escherichia coli APEC O1 4493096 YP_853860.1 CDS ygaY NC_008563.1 2980073 2981257 D transporter 2980073..2981257 Escherichia coli APEC O1 4493097 YP_853863.1 CDS ygaZ NC_008563.1 2981381 2982118 D hypothetical protein 2981381..2982118 Escherichia coli APEC O1 4493098 YP_853866.1 CDS ygaH NC_008563.1 2982108 2982443 D hypothetical protein 2982108..2982443 Escherichia coli APEC O1 4493099 YP_853870.1 CDS mprA NC_008563.1 2982534 2983064 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2982534..2983064 Escherichia coli APEC O1 4493100 YP_853871.1 CDS emrB NC_008563.1 2984380 2985918 D multidrug resistance protein B 2984380..2985918 Escherichia coli APEC O1 4493101 YP_853874.1 CDS APECO1_3836 NC_008563.1 2986176 2986883 D hypothetical protein 2986176..2986883 Escherichia coli APEC O1 4493102 YP_853878.1 CDS APECO1_3835 NC_008563.1 2986880 2987992 D hypothetical protein 2986880..2987992 Escherichia coli APEC O1 4493103 YP_853882.1 CDS luxS NC_008563.1 2988043 2988558 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(2988043..2988558) Escherichia coli APEC O1 4493105 YP_853912.1 CDS gshA NC_008563.1 2988709 2990031 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(2988709..2990031) Escherichia coli APEC O1 4493322 YP_853913.1 CDS yqaA NC_008563.1 2990338 2990673 R hypothetical protein complement(2990338..2990673) Escherichia coli APEC O1 4493323 YP_853914.1 CDS yqaB NC_008563.1 2990763 2991329 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(2990763..2991329) Escherichia coli APEC O1 4493324 YP_853916.1 CDS alaS NC_008563.1 2992939 2995569 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2992939..2995569) Escherichia coli APEC O1 4493326 YP_853917.1 CDS recX NC_008563.1 2995697 2996197 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(2995697..2996197) Escherichia coli APEC O1 4493327 YP_853918.1 CDS recA NC_008563.1 2996266 2997342 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2996266..2997342) Escherichia coli APEC O1 4493328 YP_853919.1 CDS ygaD NC_008563.1 2997407 2997904 R competence damage-inducible protein A complement(2997407..2997904) Escherichia coli APEC O1 4493329 YP_853920.1 CDS mltB NC_008563.1 2998049 2999182 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(2998049..2999182) Escherichia coli APEC O1 4493330 YP_853921.1 CDS srlA NC_008563.1 2999391 2999954 D PTS system, glucitol/sorbitol-specific IIC2 component 2999391..2999954 Escherichia coli APEC O1 4493331 YP_853922.1 CDS srlE NC_008563.1 2999951 3000910 D PTS system, glucitol/sorbitol-specific IIBC component 2999951..3000910 Escherichia coli APEC O1 4493332 YP_853923.1 CDS srlB NC_008563.1 3000921 3001292 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3000921..3001292 Escherichia coli APEC O1 4493333 YP_853924.1 CDS srlD NC_008563.1 3001296 3002075 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3001296..3002075 Escherichia coli APEC O1 4493334 YP_853925.1 CDS gutM NC_008563.1 3002181 3002540 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3002181..3002540 Escherichia coli APEC O1 4493335 YP_853926.1 CDS srlR NC_008563.1 3002607 3003380 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3002607..3003380 Escherichia coli APEC O1 4493336 YP_853927.1 CDS gutQ NC_008563.1 3003373 3004338 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3003373..3004338 Escherichia coli APEC O1 4493339 YP_853928.1 CDS ygaA NC_008563.1 3004335 3005849 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(3004335..3005849) Escherichia coli APEC O1 4494837 YP_853929.1 CDS norV NC_008563.1 3006036 3007475 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3006036..3007475 Escherichia coli APEC O1 4494838 YP_853930.1 CDS ygbD NC_008563.1 3007472 3008605 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3007472..3008605 Escherichia coli APEC O1 4494839 YP_853931.1 CDS hypF NC_008563.1 3008829 3011081 R hydrogenase maturation protein HypF complement(3008829..3011081) Escherichia coli APEC O1 4494840 YP_853932.1 CDS hydN NC_008563.1 3011234 3011761 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(3011234..3011761) Escherichia coli APEC O1 4494841 YP_853933.1 CDS ascG NC_008563.1 3011910 3012929 R ascBF operon repressor complement(3011910..3012929) Escherichia coli APEC O1 4494842 YP_853934.1 CDS ascF NC_008563.1 3013180 3014637 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 3013180..3014637 Escherichia coli APEC O1 4494843 YP_853935.1 CDS ascB NC_008563.1 3014640 3016070 D cryptic 6-phospho-beta-glucosidase 3014640..3016070 Escherichia coli APEC O1 4494844 YP_853936.1 CDS APECO1_3809 NC_008563.1 3016168 3016587 R hypothetical protein complement(3016168..3016587) Escherichia coli APEC O1 4494845 YP_853937.1 CDS hycI NC_008563.1 3016823 3017293 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3016823..3017293) Escherichia coli APEC O1 4494846 YP_853938.1 CDS hycH NC_008563.1 3017286 3017696 R formate hydrogenlyase maturation protein HycH complement(3017286..3017696) Escherichia coli APEC O1 4494847 YP_853939.1 CDS hycG NC_008563.1 3017693 3018460 R hydrogenase 3 and formate hydrogenase complex, HycG subunit complement(3017693..3018460) Escherichia coli APEC O1 4494848 YP_853940.1 CDS hycF NC_008563.1 3018460 3019002 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3018460..3019002) Escherichia coli APEC O1 4494849 YP_853941.1 CDS hycE NC_008563.1 3019012 3020721 R hydrogenase 3, large subunit complement(3019012..3020721) Escherichia coli APEC O1 4494850 YP_853942.1 CDS hycD NC_008563.1 3020739 3021662 R membrane-spanning protein of formate hydrogenase complement(3020739..3021662) Escherichia coli APEC O1 4494851 YP_853943.1 CDS hycC NC_008563.1 3021665 3023491 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3021665..3023491) Escherichia coli APEC O1 4494852 YP_853944.1 CDS hycB NC_008563.1 3023488 3024099 R hydrogenase 3, Fe-S subunit complement(3023488..3024099) Escherichia coli APEC O1 4494853 YP_853945.1 CDS hycA NC_008563.1 3024224 3024685 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3024224..3024685) Escherichia coli APEC O1 4494854 YP_853946.1 CDS hypA NC_008563.1 3024885 3025247 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3024885..3025247 Escherichia coli APEC O1 4495555 YP_853947.1 CDS hypB NC_008563.1 3025251 3026123 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3025251..3026123 Escherichia coli APEC O1 4495556 YP_853948.1 CDS hypC NC_008563.1 3026114 3026386 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3026114..3026386 Escherichia coli APEC O1 4495557 YP_853949.1 CDS hypD NC_008563.1 3026386 3027507 D hydrogenase maturation protein 3026386..3027507 Escherichia coli APEC O1 4495558 YP_853950.1 CDS hypE NC_008563.1 3027546 3028514 D carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 3027546..3028514 Escherichia coli APEC O1 4495559 YP_853951.1 CDS fhlA NC_008563.1 3028588 3030666 D formate hydrogenlyase transcriptional activator 3028588..3030666 Escherichia coli APEC O1 4495560 YP_853952.1 CDS APECO1_3793 NC_008563.1 3030696 3031139 D molybdenum-pterin-binding-protein 3030696..3031139 Escherichia coli APEC O1 4495561 YP_853953.1 CDS ygbA NC_008563.1 3031178 3031522 R hypothetical protein complement(3031178..3031522) Escherichia coli APEC O1 4495562 YP_853954.1 CDS mutS NC_008563.1 3031808 3034369 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3031808..3034369 Escherichia coli APEC O1 4495563 YP_853955.1 CDS pphB NC_008563.1 3034475 3035131 D serine/threonine-specific protein phosphatase 2 3034475..3035131 Escherichia coli APEC O1 4495564 YP_853956.1 CDS ygbI NC_008563.1 3035182 3035979 R transcriptional regulator YgbI complement(3035182..3035979) Escherichia coli APEC O1 4495565 YP_853957.1 CDS ygbJ NC_008563.1 3036145 3037053 D oxidoreductase YgbJ 3036145..3037053 Escherichia coli APEC O1 4495566 YP_853958.1 CDS ygbK NC_008563.1 3037050 3038312 D hypothetical protein 3037050..3038312 Escherichia coli APEC O1 4495567 YP_853959.1 CDS ygbL NC_008563.1 3038309 3038947 D sugar aldolase; aldolase 3038309..3038947 Escherichia coli APEC O1 4495568 YP_853960.1 CDS ygbM NC_008563.1 3038952 3039728 D hypothetical protein 3038952..3039728 Escherichia coli APEC O1 4495569 YP_853961.1 CDS ygbN NC_008563.1 3039817 3041181 D Zn-dependent hydrolase; member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3039817..3041181 Escherichia coli APEC O1 4495570 YP_853962.1 CDS APECO1_3784 NC_008563.1 3041324 3042367 R Zn-dependent hydrolase; hypothetical protein complement(3041324..3042367) Escherichia coli APEC O1 4495571 YP_853963.1 CDS APECO1_3783 NC_008563.1 3042592 3043143 D hypothetical protein 3042592..3043143 Escherichia coli APEC O1 4495572 YP_853964.1 CDS rpoS NC_008563.1 3043321 3044349 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(3043321..3044349) Escherichia coli APEC O1 4495573 YP_853965.1 CDS nlpD NC_008563.1 3044376 3045515 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3044376..3045515) Escherichia coli APEC O1 4494585 YP_853966.1 CDS pcm NC_008563.1 3045655 3046281 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3045655..3046281) Escherichia coli APEC O1 4494586 YP_853967.1 CDS surE NC_008563.1 3046275 3047036 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3046275..3047036) Escherichia coli APEC O1 4494587 YP_853968.1 CDS truD NC_008563.1 3047017 3048066 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3047017..3048066) Escherichia coli APEC O1 4494588 YP_853969.1 CDS ispF NC_008563.1 3048063 3048542 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3048063..3048542) Escherichia coli APEC O1 4494589 YP_853970.1 CDS ispD NC_008563.1 3048542 3049252 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3048542..3049252) Escherichia coli APEC O1 4494590 YP_853971.1 CDS ftsB NC_008563.1 3049271 3049582 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3049271..3049582) Escherichia coli APEC O1 4494591 YP_853972.1 CDS ygbE NC_008563.1 3049775 3050098 R hypothetical protein complement(3049775..3050098) Escherichia coli APEC O1 4494592 YP_853973.1 CDS cysC NC_008563.1 3050148 3050753 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3050148..3050753) Escherichia coli APEC O1 4494593 YP_853974.1 CDS cysN NC_008563.1 3050753 3052180 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3050753..3052180) Escherichia coli APEC O1 4494594 YP_853975.1 CDS cysD NC_008563.1 3052182 3053090 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3052182..3053090) Escherichia coli APEC O1 4494595 YP_853976.1 CDS iap NC_008563.1 3053342 3054379 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 3053342..3054379 Escherichia coli APEC O1 4494596 YP_853977.1 CDS cysH NC_008563.1 3054921 3055655 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3054921..3055655) Escherichia coli APEC O1 4494597 YP_853978.1 CDS cysI NC_008563.1 3055729 3057441 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3055729..3057441) Escherichia coli APEC O1 4494598 YP_853979.1 CDS cysJ NC_008563.1 3057441 3059240 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3057441..3059240) Escherichia coli APEC O1 4494599 YP_853980.1 CDS ygcM NC_008563.1 3059556 3059921 D 6-pyruvoyl tetrahydrobiopterin synthase 3059556..3059921 Escherichia coli APEC O1 4494600 YP_853981.1 CDS ygcN NC_008563.1 3059999 3061270 D electron transfer flavoprotein-quinone oxidoreductase YgcN 3059999..3061270 Escherichia coli APEC O1 4494601 YP_853982.1 CDS ygcO NC_008563.1 3061225 3061521 D ferredoxin-like protein YgcO 3061225..3061521 Escherichia coli APEC O1 4494602 YP_853983.1 CDS APECO1_3764 NC_008563.1 3061538 3062113 D anti-terminator regulatory protein 3061538..3062113 Escherichia coli APEC O1 4492406 YP_853984.1 CDS ygcQ NC_008563.1 3062261 3063154 R electron transfer flavoprotein subunit YgcQ complement(3062261..3063154) Escherichia coli APEC O1 4492407 YP_853985.1 CDS ygcR NC_008563.1 3063118 3063912 R electron transfer flavoprotein subunit YgcR complement(3063118..3063912) Escherichia coli APEC O1 4492408 YP_853986.1 CDS ygcS NC_008563.1 3063875 3065212 R metabolite transport protein YgcS complement(3063875..3065212) Escherichia coli APEC O1 4492409 YP_853987.1 CDS ygcU NC_008563.1 3065234 3066688 R FAD containing dehydrogenase complement(3065234..3066688) Escherichia coli APEC O1 4492410 YP_853988.1 CDS ygcW NC_008563.1 3066758 3067618 R oxidoreductase YgcW complement(3066758..3067618) Escherichia coli APEC O1 4492411 YP_853989.1 CDS yqcE NC_008563.1 3067862 3069139 D transporter 3067862..3069139 Escherichia coli APEC O1 4492412 YP_853990.1 CDS ygcE NC_008563.1 3069166 3070644 D sugar kinase 3069166..3070644 Escherichia coli APEC O1 4492413 YP_853991.1 CDS APECO1_3756 NC_008563.1 3071118 3071789 R hypothetical protein complement(3071118..3071789) Escherichia coli APEC O1 4492414 YP_853992.1 CDS APECO1_3755 NC_008563.1 3071962 3072576 D hypothetical protein 3071962..3072576 Escherichia coli APEC O1 4492415 YP_853993.1 CDS APECO1_3754 NC_008563.1 3072560 3073426 D hypothetical protein 3072560..3073426 Escherichia coli APEC O1 4492416 YP_853994.1 CDS APECO1_3753 NC_008563.1 3073499 3074647 D hypothetical protein 3073499..3074647 Escherichia coli APEC O1 4492417 YP_853995.1 CDS APECO1_3752 NC_008563.1 3074653 3075546 D hypothetical protein 3074653..3075546 Escherichia coli APEC O1 4492418 YP_853996.1 CDS eno NC_008563.1 3075606 3076904 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3075606..3076904) Escherichia coli APEC O1 4492419 YP_853997.1 CDS pyrG NC_008563.1 3076992 3078629 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3076992..3078629) Escherichia coli APEC O1 4492420 YP_853998.1 CDS mazG NC_008563.1 3078857 3079648 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(3078857..3079648) Escherichia coli APEC O1 4492421 YP_853999.1 CDS chpA NC_008563.1 3079720 3080055 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3079720..3080055) Escherichia coli APEC O1 4492422 YP_854000.1 CDS relA NC_008563.1 3080381 3082615 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3080381..3082615) Escherichia coli APEC O1 4492423 YP_854001.1 CDS rumA NC_008563.1 3082663 3083964 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3082663..3083964) Escherichia coli APEC O1 4494409 YP_854002.1 CDS barA NC_008563.1 3084021 3086777 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3084021..3086777 Escherichia coli APEC O1 4494410 YP_854003.1 CDS gudD NC_008563.1 3087008 3088348 R glucarate dehydratase complement(3087008..3088348) Escherichia coli APEC O1 4494411 YP_854004.1 CDS ygcY NC_008563.1 3088369 3089709 R glucarate dehydratase complement(3088369..3089709) Escherichia coli APEC O1 4494412 YP_854005.1 CDS gudP NC_008563.1 3089711 3091063 R D-glucarate transporter complement(3089711..3091063) Escherichia coli APEC O1 4494413 YP_854006.1 CDS yqcA NC_008563.1 3091497 3091946 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3091497..3091946) Escherichia coli APEC O1 4494414 YP_854007.1 CDS yqcB NC_008563.1 3091964 3092746 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3091964..3092746) Escherichia coli APEC O1 4494415 YP_854008.1 CDS yqcC NC_008563.1 3092746 3093075 R hypothetical protein complement(3092746..3093075) Escherichia coli APEC O1 4494416 YP_854009.1 CDS syd NC_008563.1 3093697 3093978 R SecY interacting protein Syd complement(3093697..3093978) Escherichia coli APEC O1 4494417 YP_854010.1 CDS queF NC_008563.1 3094310 3095158 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3094310..3095158 Escherichia coli APEC O1 4494418 YP_854011.1 CDS ygdH NC_008563.1 3095300 3096634 D hypothetical protein 3095300..3096634 Escherichia coli APEC O1 4494419 YP_854012.1 CDS sdaC NC_008563.1 3097191 3098480 D serine transporter 3097191..3098480 Escherichia coli APEC O1 4494420 YP_854013.1 CDS sdaB NC_008563.1 3098538 3099905 D L-serine deaminase II 3098538..3099905 Escherichia coli APEC O1 4494421 YP_854014.1 CDS exo NC_008563.1 3100128 3100772 D exodeoxyribonuclease IX 3100128..3100772 Escherichia coli APEC O1 4494422 YP_854015.1 CDS fucO NC_008563.1 3100877 3102028 R L-1,2-propanediol oxidoreductase complement(3100877..3102028) Escherichia coli APEC O1 4494423 YP_854016.1 CDS fucA NC_008563.1 3102053 3102700 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3102053..3102700) Escherichia coli APEC O1 4494424 YP_854017.1 CDS fucP NC_008563.1 3103247 3104563 D L-fucose transporter 3103247..3104563 Escherichia coli APEC O1 4494425 YP_854018.1 CDS fucI NC_008563.1 3104596 3106371 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3104596..3106371 Escherichia coli APEC O1 4494426 YP_854019.1 CDS fucK NC_008563.1 3106450 3107898 D L-fuculokinase 3106450..3107898 Escherichia coli APEC O1 4494427 YP_854020.1 CDS fucU NC_008563.1 3107900 3108322 D L-fucose mutarotase 3107900..3108322 Escherichia coli APEC O1 4491753 YP_854021.1 CDS fucR NC_008563.1 3108371 3109111 D regulates expression of genes involved in L-fucose utilization; FucR family transcriptional regulator 3108371..3109111 Escherichia coli APEC O1 4491754 YP_854022.1 CDS ygdE NC_008563.1 3109155 3110255 R RNA 2'-O-ribose methyltransferase complement(3109155..3110255) Escherichia coli APEC O1 4491755 YP_854023.1 CDS APECO1_3724 NC_008563.1 3110248 3110643 R hypothetical protein complement(3110248..3110643) Escherichia coli APEC O1 4491756 YP_854024.1 CDS gcvA NC_008563.1 3110662 3111579 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3110662..3111579) Escherichia coli APEC O1 4491757 YP_854025.1 CDS csdA NC_008563.1 3112349 3113554 D cysteine sulfinate desulfinase 3112349..3113554 Escherichia coli APEC O1 4491758 YP_854026.1 CDS ygdK NC_008563.1 3113554 3113997 D Fe-S metabolism protein 3113554..3113997 Escherichia coli APEC O1 4491759 YP_854027.1 CDS ygdL NC_008563.1 3114048 3114854 R hypothetical protein complement(3114048..3114854) Escherichia coli APEC O1 4491760 YP_854028.2 CDS mltA NC_008563.1 3114931 3116028 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3114931..3116028) Escherichia coli APEC O1 4491761 YP_854029.1 CDS APECO1_3718 NC_008563.1 3117169 3117669 D hypothetical protein 3117169..3117669 Escherichia coli APEC O1 4491762 YP_854030.1 CDS APECO1_3717 NC_008563.1 3117722 3119266 D hypothetical protein 3117722..3119266 Escherichia coli APEC O1 4491763 YP_854031.1 CDS APECO1_3716 NC_008563.1 3119284 3120621 D hypothetical protein 3119284..3120621 Escherichia coli APEC O1 4491764 YP_854032.1 CDS APECO1_3715 NC_008563.1 3120618 3121283 D hypothetical protein 3120618..3121283 Escherichia coli APEC O1 4491765 YP_854033.1 CDS APECO1_3714 NC_008563.1 3121335 3122948 D outer membrane protein 3121335..3122948 Escherichia coli APEC O1 4491766 YP_854034.1 CDS APECO1_3713 NC_008563.1 3123006 3123497 D hemolysin-coregulated protein 3123006..3123497 Escherichia coli APEC O1 4491767 YP_854035.1 CDS APECO1_3712 NC_008563.1 3123689 3126334 D ATPase 3123689..3126334 Escherichia coli APEC O1 4491768 YP_854036.1 CDS APECO1_3711 NC_008563.1 3126346 3128826 D hypothetical protein 3126346..3128826 Escherichia coli APEC O1 4491769 YP_854037.1 CDS APECO1_3710 NC_008563.1 3128846 3130012 D hypothetical protein 3128846..3130012 Escherichia coli APEC O1 4491770 YP_854038.1 CDS APECO1_3709 NC_008563.1 3130225 3130605 D hypothetical protein 3130225..3130605 Escherichia coli APEC O1 4491771 YP_854039.1 CDS APECO1_3708 NC_008563.1 3130580 3131413 D hypothetical protein 3130580..3131413 Escherichia coli APEC O1 4495613 YP_854040.1 CDS APECO1_3707 NC_008563.1 3131382 3131675 D hypothetical protein 3131382..3131675 Escherichia coli APEC O1 4495614 YP_854041.1 CDS APECO1_3705 NC_008563.1 3133547 3136885 D hypothetical protein 3133547..3136885 Escherichia coli APEC O1 4495615 YP_854042.1 CDS APECO1_3704 NC_008563.1 3136943 3137692 R ISEc12 ATP-binding protein complement(3136943..3137692) Escherichia coli APEC O1 4495616 YP_854043.1 CDS APECO1_3703 NC_008563.1 3137704 3139245 R transposase for ISEc12 complement(3137704..3139245) Escherichia coli APEC O1 4495617 YP_854044.1 CDS APECO1_3702 NC_008563.1 3139452 3141089 D hypothetical protein 3139452..3141089 Escherichia coli APEC O1 4495618 YP_854045.1 CDS APECO1_3701 NC_008563.1 3141089 3142672 D hypothetical protein 3141089..3142672 Escherichia coli APEC O1 4495619 YP_854046.1 CDS APECO1_3700 NC_008563.1 3142672 3143301 D hypothetical protein 3142672..3143301 Escherichia coli APEC O1 4495620 YP_854047.1 CDS APECO1_3699 NC_008563.1 3143558 3144001 D hypothetical protein 3143558..3144001 Escherichia coli APEC O1 4495621 YP_854048.1 CDS APECO1_3698 NC_008563.1 3144371 3146131 D hypothetical protein 3144371..3146131 Escherichia coli APEC O1 4495622 YP_854049.1 CDS APECO1_3697 NC_008563.1 3146095 3147174 D hypothetical protein 3146095..3147174 Escherichia coli APEC O1 4495623 YP_854050.1 CDS APECO1_3696 NC_008563.1 3147155 3147691 D hypothetical protein 3147155..3147691 Escherichia coli APEC O1 4495624 YP_854051.1 CDS APECO1_3695 NC_008563.1 3147695 3148123 D hypothetical protein 3147695..3148123 Escherichia coli APEC O1 4495625 YP_854052.1 CDS APECO1_3694 NC_008563.1 3148123 3149499 D hypothetical protein 3148123..3149499 Escherichia coli APEC O1 4495626 YP_854053.1 CDS APECO1_3693 NC_008563.1 3149801 3150748 R 2-hydroxyacid dehydrogenase complement(3149801..3150748) Escherichia coli APEC O1 4495627 YP_854054.1 CDS APECO1_3692 NC_008563.1 3150820 3151416 R phosphosugar isomerase complement(3150820..3151416) Escherichia coli APEC O1 4495628 YP_854055.1 CDS APECO1_3691 NC_008563.1 3151419 3152594 R aminotransferase complement(3151419..3152594) Escherichia coli APEC O1 4495629 YP_854056.1 CDS APECO1_3690 NC_008563.1 3152594 3154174 R PTS system, maltose and glucose-specific IIABC component complement(3152594..3154174) Escherichia coli APEC O1 4495630 YP_854057.1 CDS APECO1_3689 NC_008563.1 3154206 3155087 R antiterminator complement(3154206..3155087) Escherichia coli APEC O1 4495631 YP_854058.1 CDS amiC NC_008563.1 3155288 3156631 R N-acetylmuramoyl-L-alanine amidase complement(3155288..3156631) Escherichia coli APEC O1 4495632 YP_854059.1 CDS argA NC_008563.1 3156863 3158104 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3156863..3158104 Escherichia coli APEC O1 4492240 YP_854060.1 CDS recD NC_008563.1 3158166 3159992 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3158166..3159992) Escherichia coli APEC O1 4492241 YP_854061.1 CDS recB NC_008563.1 3159992 3163534 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3159992..3163534) Escherichia coli APEC O1 4492242 YP_854062.1 CDS ptrA NC_008563.1 3163527 3166415 R protease III complement(3163527..3166415) Escherichia coli APEC O1 4492243 YP_854063.1 CDS recC NC_008563.1 3166591 3169959 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3166591..3169959) Escherichia coli APEC O1 4492244 YP_854064.1 CDS ppdC NC_008563.1 3169972 3170295 R hypothetical protein complement(3169972..3170295) Escherichia coli APEC O1 4492245 YP_854065.1 CDS ygdB NC_008563.1 3170280 3170645 R hypothetical protein complement(3170280..3170645) Escherichia coli APEC O1 4492246 YP_854066.1 CDS ppdB NC_008563.1 3170684 3171487 R hypothetical protein complement(3170684..3171487) Escherichia coli APEC O1 4492247 YP_854067.1 CDS ppdA NC_008563.1 3171238 3171708 R type II secretory pathway, pseudopilin; hypothetical protein complement(3171238..3171708) Escherichia coli APEC O1 4492248 YP_854068.1 CDS thyA NC_008563.1 3171893 3172687 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3171893..3172687) Escherichia coli APEC O1 4492249 YP_854069.1 CDS lgt NC_008563.1 3172694 3173569 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3172694..3173569) Escherichia coli APEC O1 4492250 YP_854070.1 CDS ptsP NC_008563.1 3173720 3175966 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3173720..3175966) Escherichia coli APEC O1 4492251 YP_854071.1 CDS ygdP NC_008563.1 3175979 3176443 R dinucleoside polyphosphate hydrolase complement(3175979..3176443) Escherichia coli APEC O1 4492252 YP_854072.1 CDS mutH NC_008563.1 3177194 3177883 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3177194..3177883 Escherichia coli APEC O1 4492253 YP_854073.1 CDS terC NC_008563.1 3177952 3178665 D possibly involved in tellurite resistance; integral membrane protein TerC 3177952..3178665 Escherichia coli APEC O1 4492254 YP_854074.1 CDS tas NC_008563.1 3179129 3180169 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3179129..3180169 Escherichia coli APEC O1 4492255 YP_854075.1 CDS ygeD NC_008563.1 3180201 3181394 R lysophospholipid transporter LplT complement(3180201..3181394) Escherichia coli APEC O1 4492256 YP_854076.1 CDS aas NC_008563.1 3181387 3183546 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3181387..3183546) Escherichia coli APEC O1 4492257 YP_854077.1 CDS galR NC_008563.1 3184132 3185163 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3184132..3185163 Escherichia coli APEC O1 4492258 YP_854078.1 CDS lysA NC_008563.1 3185170 3186432 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3185170..3186432) Escherichia coli APEC O1 4491518 YP_854079.1 CDS lysR NC_008563.1 3186554 3187489 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3186554..3187489 Escherichia coli APEC O1 4491519 YP_854080.1 CDS ygeA NC_008563.1 3187476 3188168 R Asp/Glu/Hydantoin racemase family; racemase complement(3187476..3188168) Escherichia coli APEC O1 4491520 YP_854081.1 CDS araE NC_008563.1 3188297 3189715 R arabinose transporter complement(3188297..3189715) Escherichia coli APEC O1 4491521 YP_854082.1 CDS kduD NC_008563.1 3190030 3190791 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3190030..3190791) Escherichia coli APEC O1 4491522 YP_854083.1 CDS kduI NC_008563.1 3190821 3191549 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3190821..3191549) Escherichia coli APEC O1 4491523 YP_854084.1 CDS yqeF NC_008563.1 3191944 3193125 R thiolase domain; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3191944..3193125) Escherichia coli APEC O1 4491524 YP_854085.1 CDS yqeG NC_008563.1 3193380 3194609 D transporter 3193380..3194609 Escherichia coli APEC O1 4491525 YP_854086.1 CDS ygeR NC_008563.1 3195078 3195791 R lipoportein complement(3195078..3195791) Escherichia coli APEC O1 4491526 YP_854087.1 CDS APECO1_3659 NC_008563.1 3196247 3198544 D aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3196247..3198544 Escherichia coli APEC O1 4491527 YP_854088.1 CDS ygeT NC_008563.1 3198555 3199433 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3198555..3199433 Escherichia coli APEC O1 4491528 YP_854089.1 CDS ygeV NC_008563.1 3199949 3201727 R regulatory protein; DNA-binding transcriptional regulator complement(3199949..3201727) Escherichia coli APEC O1 4491529 YP_854090.1 CDS ygeW NC_008563.1 3202203 3203393 D aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase family protein 3202203..3203393 Escherichia coli APEC O1 4491530 YP_854091.1 CDS ygeX NC_008563.1 3203451 3204647 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3203451..3204647 Escherichia coli APEC O1 4491531 YP_854092.1 CDS ygeY NC_008563.1 3204705 3205916 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3204705..3205916 Escherichia coli APEC O1 4491532 YP_854093.1 CDS ygeZ NC_008563.1 3205969 3207354 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3205969..3207354 Escherichia coli APEC O1 4491533 YP_854094.1 CDS yqeA NC_008563.1 3207402 3208334 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3207402..3208334 Escherichia coli APEC O1 4491534 YP_854095.1 CDS yqeB NC_008563.1 3208375 3210000 R synthase complement(3208375..3210000) Escherichia coli APEC O1 4491535 YP_854096.1 CDS yqeC NC_008563.1 3210048 3210650 R hypothetical protein complement(3210048..3210650) Escherichia coli APEC O1 4491536 YP_854097.1 CDS ygfJ NC_008563.1 3210922 3211500 D hypothetical protein 3210922..3211500 Escherichia coli APEC O1 4491537 YP_854098.1 CDS ygfK NC_008563.1 3211822 3214920 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3211822..3214920 Escherichia coli APEC O1 4494913 YP_854099.1 CDS ssnA NC_008563.1 3214923 3216251 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3214923..3216251 Escherichia coli APEC O1 4494914 YP_854100.1 CDS ygfM NC_008563.1 3216302 3217081 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3216302..3217081 Escherichia coli APEC O1 4494915 YP_854101.1 CDS xdhD NC_008563.1 3217078 3219948 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3217078..3219948 Escherichia coli APEC O1 4494916 YP_854102.1 CDS ygfO NC_008563.1 3220113 3221513 D transporter 3220113..3221513 Escherichia coli APEC O1 4494917 YP_854103.1 CDS ygfP NC_008563.1 3221528 3222847 D Catalyzes the deamination of guanine; guanine deaminase 3221528..3222847 Escherichia coli APEC O1 4494918 YP_854104.1 CDS ygfQ NC_008563.1 3222883 3224250 D transporter 3222883..3224250 Escherichia coli APEC O1 4494919 YP_854105.1 CDS ygfS NC_008563.1 3224286 3224774 R oxidoreductase, 4Fe-4S ferredoxin-type subunit complement(3224286..3224774) Escherichia coli APEC O1 4494920 YP_854106.1 CDS ygfT NC_008563.1 3224774 3226708 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3224774..3226708) Escherichia coli APEC O1 4494921 YP_854107.1 CDS ygfU NC_008563.1 3227060 3228577 D purine permease YgfU 3227060..3228577 Escherichia coli APEC O1 4494922 YP_854108.1 CDS APECO1_3638 NC_008563.1 3228827 3229375 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3228827..3229375 Escherichia coli APEC O1 4494923 YP_854109.1 CDS lysS NC_008563.1 3229418 3230935 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3229418..3230935) Escherichia coli APEC O1 4494924 YP_854110.1 CDS prfB NC_008563.1 3230945 3231826 R peptide chain release factor 2 complement(3230945..3231826) Escherichia coli APEC O1 4494925 YP_854111.1 CDS APECO1_3635 NC_008563.1 3232134 3233726 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3232134..3233726) Escherichia coli APEC O1 4494926 YP_854112.1 CDS dsbC NC_008563.1 3233873 3234583 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3233873..3234583) Escherichia coli APEC O1 4494927 YP_854113.1 CDS xerD NC_008563.1 3234608 3235402 R site-specific tyrosine recombinase XerD complement(3234608..3235402) Escherichia coli APEC O1 4494928 YP_854114.1 CDS fldB NC_008563.1 3235616 3236137 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3235616..3236137 Escherichia coli APEC O1 4494929 YP_854115.1 CDS APECO1_3631 NC_008563.1 3236177 3236491 R hypothetical protein complement(3236177..3236491) Escherichia coli APEC O1 4494930 YP_854116.1 CDS APECO1_3630 NC_008563.1 3236565 3236831 R hypothetical protein complement(3236565..3236831) Escherichia coli APEC O1 4494931 YP_854117.1 CDS ygfZ NC_008563.1 3237074 3238054 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3237074..3238054 Escherichia coli APEC O1 4493126 YP_854118.1 CDS yqfA NC_008563.1 3238131 3238790 R oxidoreductase, inner membrane subunit complement(3238131..3238790) Escherichia coli APEC O1 4493127 YP_854119.1 CDS APECO1_3627 NC_008563.1 3238954 3239265 R hypothetical protein complement(3238954..3239265) Escherichia coli APEC O1 4493128 YP_854120.1 CDS bglA NC_008563.1 3239304 3240743 D 6-phospho-beta-glucosidase 3239304..3240743 Escherichia coli APEC O1 4493129 YP_854121.1 CDS gcvP NC_008563.1 3240909 3243782 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3240909..3243782) Escherichia coli APEC O1 4493130 YP_854122.1 CDS gcvH NC_008563.1 3243900 3244289 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3243900..3244289) Escherichia coli APEC O1 4493131 YP_854123.2 CDS gcvT NC_008563.1 3244313 3245407 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3244313..3245407) Escherichia coli APEC O1 4493132 YP_854124.1 CDS visC NC_008563.1 3245855 3247057 R hypothetical protein complement(3245855..3247057) Escherichia coli APEC O1 4493133 YP_854125.1 CDS ubiH NC_008563.1 3247080 3248258 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3247080..3248258) Escherichia coli APEC O1 4493134 YP_854126.1 CDS pepB NC_008563.1 3248255 3249580 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3248255..3249580) Escherichia coli APEC O1 4493135 YP_854127.2 CDS ygfB NC_008563.1 3249606 3250184 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3249606..3250184) Escherichia coli APEC O1 4493136 YP_854128.1 CDS APECO1_3618 NC_008563.1 3250352 3250681 D Z-ring-associated protein 3250352..3250681 Escherichia coli APEC O1 4493137 YP_854129.2 CDS APECO1_3617 NC_008563.1 3250981 3251529 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3250981..3251529 Escherichia coli APEC O1 4493138 YP_854130.1 CDS serA NC_008563.1 3251919 3253151 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3251919..3253151) Escherichia coli APEC O1 4493139 YP_854131.1 CDS rpiA NC_008563.1 3253407 3254102 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3253407..3254102) Escherichia coli APEC O1 4493140 YP_854132.2 CDS iciA NC_008563.1 3254493 3255386 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3254493..3255386 Escherichia coli APEC O1 4493141 YP_854133.1 CDS APECO1_3613 NC_008563.1 3255589 3256644 D hypothetical protein 3255589..3256644 Escherichia coli APEC O1 4493142 YP_854134.1 CDS ygfI NC_008563.1 3256641 3257537 R transcriptional regulator YgfI complement(3256641..3257537) Escherichia coli APEC O1 4493143 YP_854135.1 CDS yggE NC_008563.1 3257695 3258402 R hypothetical protein complement(3257695..3258402) Escherichia coli APEC O1 4493144 YP_854136.1 CDS yggA NC_008563.1 3258528 3259118 R Involved in the export of arginine; arginine exporter protein complement(3258528..3259118) Escherichia coli APEC O1 4493145 YP_854137.1 CDS mscS NC_008563.1 3259299 3260159 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3259299..3260159) Escherichia coli APEC O1 4495155 YP_854138.1 CDS fba NC_008563.1 3260350 3261429 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3260350..3261429) Escherichia coli APEC O1 4495156 YP_854139.1 CDS pgk NC_008563.1 3261644 3262807 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3261644..3262807) Escherichia coli APEC O1 4495157 YP_854140.1 CDS epd NC_008563.1 3262857 3263876 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3262857..3263876) Escherichia coli APEC O1 4495158 YP_854141.1 CDS APECO1_3605 NC_008563.1 3264248 3264679 D hypothetical protein 3264248..3264679 Escherichia coli APEC O1 4495159 YP_854142.1 CDS APECO1_3604 NC_008563.1 3264702 3265280 D hypothetical protein 3264702..3265280 Escherichia coli APEC O1 4495160 YP_854143.1 CDS APECO1_3603 NC_008563.1 3265281 3265988 D permease protein of ABC-type cobalt transporter 3265281..3265988 Escherichia coli APEC O1 4495161 YP_854144.1 CDS APECO1_3602 NC_008563.1 3265976 3266653 D ABC transporter ATP-binding protein 3265976..3266653 Escherichia coli APEC O1 4495162 YP_854145.1 CDS APECO1_3601 NC_008563.1 3266647 3267324 D ABC transporter ATP-binding protein 3266647..3267324 Escherichia coli APEC O1 4495163 YP_854146.1 CDS frcK NC_008563.1 3267296 3267919 R fructose transport system kinase complement(3267296..3267919) Escherichia coli APEC O1 4495164 YP_854147.1 CDS yggD NC_008563.1 3268006 3268515 R DNA-binding transcriptional regulator complement(3268006..3268515) Escherichia coli APEC O1 4495165 YP_854148.1 CDS APECO1_3598 NC_008563.1 3268849 3270126 R oxidoreductase complement(3268849..3270126) Escherichia coli APEC O1 4495166 YP_854149.1 CDS cmtA NC_008563.1 3270141 3271529 R PTS system, mannitol (cryptic)-specific IIBC component complement(3270141..3271529) Escherichia coli APEC O1 4495167 YP_854150.1 CDS cmtB NC_008563.1 3271557 3272000 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3271557..3272000) Escherichia coli APEC O1 4495168 YP_854151.1 CDS APECO1_3595 NC_008563.1 3272377 3273285 D serine protease 3272377..3273285 Escherichia coli APEC O1 4495169 YP_854152.1 CDS tktA NC_008563.1 3273505 3275496 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3273505..3275496) Escherichia coli APEC O1 4495170 YP_854153.1 CDS yggG NC_008563.1 3275648 3276532 D metalloprotease YggG 3275648..3276532 Escherichia coli APEC O1 4495171 YP_854154.1 CDS speB NC_008563.1 3276736 3277656 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3276736..3277656) Escherichia coli APEC O1 4495172 YP_854155.1 CDS APECO1_3591 NC_008563.1 3277792 3278523 R hypothetical protein complement(3277792..3278523) Escherichia coli APEC O1 4495173 YP_854156.1 CDS speA NC_008563.1 3278669 3280645 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3278669..3280645) Escherichia coli APEC O1 4493225 YP_854157.1 CDS metK NC_008563.1 3281440 3282594 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3281440..3282594 Escherichia coli APEC O1 4493226 YP_854158.1 CDS galP NC_008563.1 3283031 3284425 D D-galactose transporter 3283031..3284425 Escherichia coli APEC O1 4493227 YP_854159.1 CDS sprT NC_008563.1 3284502 3284999 D hypothetical protein 3284502..3284999 Escherichia coli APEC O1 4493228 YP_854160.1 CDS endA NC_008563.1 3285094 3285801 D DNA-specific endonuclease I 3285094..3285801 Escherichia coli APEC O1 4493229 YP_854161.1 CDS yggJ NC_008563.1 3285881 3286612 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3285881..3286612 Escherichia coli APEC O1 4493230 YP_854162.1 CDS gshB NC_008563.1 3286625 3287575 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3286625..3287575 Escherichia coli APEC O1 4493231 YP_854163.1 CDS yqgE NC_008563.1 3287684 3288247 D hypothetical protein 3287684..3288247 Escherichia coli APEC O1 4493232 YP_854164.1 CDS yqgF NC_008563.1 3288247 3288663 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3288247..3288663 Escherichia coli APEC O1 4493233 YP_854165.1 CDS yggR NC_008563.1 3288837 3289817 R hypothetical protein complement(3288837..3289817) Escherichia coli APEC O1 4493234 YP_854166.1 CDS yggS NC_008563.1 3289835 3290539 D hypothetical protein 3289835..3290539 Escherichia coli APEC O1 4493235 YP_854167.1 CDS yggT NC_008563.1 3290557 3291123 D hypothetical protein 3290557..3291123 Escherichia coli APEC O1 4493236 YP_854168.1 CDS yggU NC_008563.1 3291120 3291410 D hypothetical protein 3291120..3291410 Escherichia coli APEC O1 4493237 YP_854169.1 CDS yggV NC_008563.1 3291418 3292011 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3291418..3292011 Escherichia coli APEC O1 4493238 YP_854170.1 CDS yggW NC_008563.1 3292004 3293140 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3292004..3293140 Escherichia coli APEC O1 4493239 YP_854171.1 CDS yggM NC_008563.1 3293209 3294180 R hypothetical protein complement(3293209..3294180) Escherichia coli APEC O1 4493240 YP_854172.1 CDS ansB NC_008563.1 3294333 3295379 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3294333..3295379) Escherichia coli APEC O1 4493241 YP_854173.1 CDS yggN NC_008563.1 3295555 3296274 R hypothetical protein complement(3295555..3296274) Escherichia coli APEC O1 4493242 YP_854174.1 CDS yggL NC_008563.1 3296458 3296784 R hypothetical protein complement(3296458..3296784) Escherichia coli APEC O1 4493243 YP_854175.1 CDS trmB NC_008563.1 3296784 3297503 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3296784..3297503) Escherichia coli APEC O1 4493244 YP_854176.1 CDS mutY NC_008563.1 3297664 3298716 D adenine DNA glycosylase 3297664..3298716 Escherichia coli APEC O1 4493812 YP_854177.1 CDS yggX NC_008563.1 3298744 3299019 D hypothetical protein 3298744..3299019 Escherichia coli APEC O1 4493813 YP_854206.1 CDS mltC NC_008563.1 3299081 3300163 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3299081..3300163 Escherichia coli APEC O1 4493814 YP_854208.1 CDS nupG NC_008563.1 3300317 3301621 D transport of nucleosides, permease protein 3300317..3301621 Escherichia coli APEC O1 4493815 YP_854211.1 CDS speC NC_008563.1 3301670 3303805 R ornithine decarboxylase complement(3301670..3303805) Escherichia coli APEC O1 4493816 YP_854213.1 CDS yqgA NC_008563.1 3304303 3304911 D hypothetical protein 3304303..3304911 Escherichia coli APEC O1 4493817 YP_854214.1 CDS APECO1_3534 NC_008563.1 3305290 3306552 D integrase core domain; P4-like integrase 3305290..3306552 Escherichia coli APEC O1 4493818 YP_854225.1 CDS APECO1_3533 NC_008563.1 3306652 3306915 R hypothetical protein complement(3306652..3306915) Escherichia coli APEC O1 4493819 YP_854230.1 CDS APECO1_3532 NC_008563.1 3306992 3310519 D superfamily I DNA helicase 3306992..3310519 Escherichia coli APEC O1 4493820 YP_854244.1 CDS APECO1_3531 NC_008563.1 3310628 3312127 R hypothetical protein complement(3310628..3312127) Escherichia coli APEC O1 4493821 YP_854245.1 CDS tia NC_008563.1 3312302 3313057 R tia invasion determinant complement(3312302..3313057) Escherichia coli APEC O1 4493822 YP_854246.1 CDS APECO1_3529 NC_008563.1 3313158 3313907 R ISEc12 ATP-binding protein complement(3313158..3313907) Escherichia coli APEC O1 4493823 YP_854247.1 CDS APECO1_3528 NC_008563.1 3313919 3315460 R transposase for ISEc12 complement(3313919..3315460) Escherichia coli APEC O1 4493824 YP_854248.1 CDS papG NC_008563.1 3315994 3317004 R allele II; protein PapG complement(3315994..3317004) Escherichia coli APEC O1 4493827 YP_854249.1 CDS papF NC_008563.1 3317048 3317578 R P pilus minor tip component PapF complement(3317048..3317578) Escherichia coli APEC O1 4493828 YP_854250.1 CDS papE NC_008563.1 3317623 3318144 R PapE protein complement(3317623..3318144) Escherichia coli APEC O1 4493829 YP_854251.1 CDS papK NC_008563.1 3318171 3318707 R pilus assembly protein PapK complement(3318171..3318707) Escherichia coli APEC O1 4493830 YP_854252.1 CDS papJ NC_008563.1 3318717 3319298 R PapJ protein complement(3318717..3319298) Escherichia coli APEC O1 4493547 YP_854253.1 CDS papD NC_008563.1 3319335 3320069 R pilus assembly protein chaperone PapD complement(3319335..3320069) Escherichia coli APEC O1 4493548 YP_854254.1 CDS papC NC_008563.1 3320140 3322659 R outer membrane usher protein PapC complement(3320140..3322659) Escherichia coli APEC O1 4493549 YP_854255.1 CDS papH NC_008563.1 3322709 3323296 R minor pilin subunit PapH complement(3322709..3323296) Escherichia coli APEC O1 4493550 YP_854256.1 CDS papA NC_008563.1 3323359 3323928 R major fibrial protein complement(3323359..3323928) Escherichia coli APEC O1 4493551 YP_854257.1 CDS APECO1_3518 NC_008563.1 3324114 3324428 R fimbrial regulatory protein; PapB-like protein complement(3324114..3324428) Escherichia coli APEC O1 4493552 YP_854258.1 CDS papI NC_008563.1 3324732 3325037 R fimbrial regulatory protein complement(3324732..3325037) Escherichia coli APEC O1 4493553 YP_854259.1 CDS APECO1_3516 NC_008563.1 3325337 3325663 D hypothetical protein 3325337..3325663 Escherichia coli APEC O1 4493554 YP_854260.1 CDS APECO1_3515 NC_008563.1 3325741 3326316 R hypothetical protein complement(3325741..3326316) Escherichia coli APEC O1 4493555 YP_854261.1 CDS APECO1_3514 NC_008563.1 3326574 3327140 R hypothetical protein complement(3326574..3327140) Escherichia coli APEC O1 4493556 YP_854262.1 CDS insC NC_008563.1 3327566 3327856 D IS2 transposase 3327566..3327856 Escherichia coli APEC O1 4493557 YP_854263.1 CDS insD NC_008563.1 3327814 3328527 D IS2 transposase 3327814..3328527 Escherichia coli APEC O1 4493558 YP_854264.1 CDS APECO1_3511 NC_008563.1 3328729 3329094 R hypothetical protein complement(3328729..3329094) Escherichia coli APEC O1 4493559 YP_854265.1 CDS pgtP NC_008563.1 3329137 3330501 R phosphoglycerate transporter protein PgtP complement(3329137..3330501) Escherichia coli APEC O1 4493560 YP_854266.1 CDS pgtC NC_008563.1 3330846 3332117 D phosphoglycerate transport regulatory protein 3330846..3332117 Escherichia coli APEC O1 4493561 YP_854267.1 CDS pgtB NC_008563.1 3332114 3334123 D regulatory protein 3332114..3334123 Escherichia coli APEC O1 4493562 YP_854268.1 CDS pgtA NC_008563.1 3334104 3335360 D phosphoglycerate activator protein 3334104..3335360 Escherichia coli APEC O1 4493563 YP_854270.1 CDS APECO1_3506 NC_008563.1 3335953 3336258 R hypothetical protein complement(3335953..3336258) Escherichia coli APEC O1 4493564 YP_854272.1 CDS APECO1_3505 NC_008563.1 3336341 3336985 R hypothetical protein complement(3336341..3336985) Escherichia coli APEC O1 4493565 YP_854275.1 CDS APECO1_3504 NC_008563.1 3337006 3337275 R similar to transcriptional regulator; hypothetical protein complement(3337006..3337275) Escherichia coli APEC O1 4493566 YP_854305.1 CDS APECO1_3503 NC_008563.1 3337436 3337999 R hypothetical protein complement(3337436..3337999) Escherichia coli APEC O1 4491363 YP_854308.1 CDS APECO1_3502 NC_008563.1 3337984 3339216 R hypothetical protein complement(3337984..3339216) Escherichia coli APEC O1 4491364 YP_854310.1 CDS APECO1_3501 NC_008563.1 3339352 3339996 R hypothetical protein complement(3339352..3339996) Escherichia coli APEC O1 4491365 YP_854311.1 CDS APECO1_3500 NC_008563.1 3340190 3341638 R hypothetical protein complement(3340190..3341638) Escherichia coli APEC O1 4491366 YP_854312.1 CDS APECO1_3499 NC_008563.1 3341809 3342696 R transposase for IS629 complement(3341809..3342696) Escherichia coli APEC O1 4491367 YP_854313.1 CDS APECO1_3498 NC_008563.1 3342696 3343022 R transposase; OrfA protein of insertion sequence IS629 complement(3342696..3343022) Escherichia coli APEC O1 4491368 YP_854314.1 CDS ireA NC_008563.1 3344416 3346464 R iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein; iron-regulated outer membrane virulence protein complement(3344416..3346464) Escherichia coli APEC O1 4491369 YP_854315.1 CDS APECO1_3496 NC_008563.1 3347238 3347978 R hypothetical protein complement(3347238..3347978) Escherichia coli APEC O1 4491370 YP_854316.1 CDS APECO1_3495 NC_008563.1 3349670 3350458 D hypothetical protein 3349670..3350458 Escherichia coli APEC O1 4491371 YP_854317.1 CDS APECO1_3494 NC_008563.1 3350455 3351405 R hypothetical protein complement(3350455..3351405) Escherichia coli APEC O1 4491372 YP_854318.1 CDS APECO1_3493 NC_008563.1 3351511 3352395 D hypothetical protein 3351511..3352395 Escherichia coli APEC O1 4491373 YP_854319.1 CDS APECO1_3492 NC_008563.1 3352598 3353278 D transcriptional regulator 3352598..3353278 Escherichia coli APEC O1 4491374 YP_854320.1 CDS APECO1_3491 NC_008563.1 3353321 3354103 D hypothetical protein 3353321..3354103 Escherichia coli APEC O1 4491375 YP_854321.1 CDS yafZ NC_008563.1 3354432 3355250 D hypothetical protein 3354432..3355250 Escherichia coli APEC O1 4491376 YP_854322.1 CDS yfjX NC_008563.1 3355341 3355826 D hypothetical protein 3355341..3355826 Escherichia coli APEC O1 4491377 YP_854323.1 CDS yeeS NC_008563.1 3355841 3356317 D radC-like protein YeeS 3355841..3356317 Escherichia coli APEC O1 4491378 YP_854324.1 CDS yeeU NC_008563.1 3356626 3357063 D hypothetical protein 3356626..3357063 Escherichia coli APEC O1 4491379 YP_854325.1 CDS yeeV NC_008563.1 3357110 3357487 D hypothetical protein 3357110..3357487 Escherichia coli APEC O1 4491380 YP_854326.1 CDS APECO1_3485 NC_008563.1 3357484 3357972 D hypothetical protein 3357484..3357972 Escherichia coli APEC O1 4491381 YP_854327.1 CDS APECO1_3484 NC_008563.1 3358266 3359111 D hypothetical protein 3358266..3359111 Escherichia coli APEC O1 4494199 YP_854328.1 CDS APECO1_3483 NC_008563.1 3359182 3360717 D hypothetical protein 3359182..3360717 Escherichia coli APEC O1 4494200 YP_854329.1 CDS kpsF NC_008563.1 3362058 3363077 D polysialic acid capsule synthesis protein KpsF 3362058..3363077 Escherichia coli APEC O1 4494201 YP_854330.1 CDS kpsE NC_008563.1 3363149 3364297 D polysialic acid transport protein KpsE 3363149..3364297 Escherichia coli APEC O1 4494202 YP_854331.1 CDS kpsD NC_008563.1 3364321 3365997 D polysialic acid transport protein KpsD precursor 3364321..3365997 Escherichia coli APEC O1 4494203 YP_854332.1 CDS kpsU NC_008563.1 3366007 3366747 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3366007..3366747 Escherichia coli APEC O1 4494204 YP_854335.1 CDS kpsC NC_008563.1 3366744 3368771 D capsule polysaccharide export protein KpsC 3366744..3368771 Escherichia coli APEC O1 4494205 YP_854344.1 CDS kpsS NC_008563.1 3368806 3370011 D polysialic acid capsule synthesis protein KpsS 3368806..3370011 Escherichia coli APEC O1 4494206 YP_854390.1 CDS neuS NC_008563.1 3370161 3371390 R poly-alpha-2,8 sialosyl sialyltransferase NeuS complement(3370161..3371390) Escherichia coli APEC O1 4494207 YP_854391.1 CDS neuE NC_008563.1 3371380 3372555 R polysialic acid biosynthesis protein NeuE complement(3371380..3372555) Escherichia coli APEC O1 4494208 YP_854392.1 CDS neuC NC_008563.1 3372521 3373696 R polysialic acid biosynthesis protein complement(3372521..3373696) Escherichia coli APEC O1 4494209 YP_854393.1 CDS neuA NC_008563.1 3373693 3374949 R acylneuraminate cytidylyltransferase complement(3373693..3374949) Escherichia coli APEC O1 4494210 YP_854394.1 CDS neuB NC_008563.1 3374949 3375989 R sialic acid synthase complement(3374949..3375989) Escherichia coli APEC O1 4494211 YP_854395.1 CDS neuD NC_008563.1 3375986 3376609 R sialic acid synthase complement(3375986..3376609) Escherichia coli APEC O1 4494212 YP_854396.1 CDS kpsT NC_008563.1 3376659 3377318 R polysialic acid transport ATP-binding protein KpsT complement(3376659..3377318) Escherichia coli APEC O1 4494213 YP_854397.1 CDS kpsM NC_008563.1 3377315 3378091 R polysialic acid transport protein KpsM complement(3377315..3378091) Escherichia coli APEC O1 4494214 YP_854398.1 CDS gspM NC_008563.1 3379149 3379685 R general secretion pathway protein YghD complement(3379149..3379685) Escherichia coli APEC O1 4494215 YP_854399.2 CDS gspL NC_008563.1 3379687 3380547 R similar to general secretory pathway protein L; GspL-like protein complement(3379687..3380547) Escherichia coli APEC O1 4494216 YP_854400.1 CDS gspK NC_008563.1 3380862 3381839 R type II secretion protein GspK complement(3380862..3381839) Escherichia coli APEC O1 4494217 YP_854401.1 CDS gspJ NC_008563.1 3381836 3382441 R type II secretion protein GspJ complement(3381836..3382441) Escherichia coli APEC O1 4494218 YP_854402.1 CDS gspI NC_008563.1 3382438 3382809 R type II secretion protein GspI complement(3382438..3382809) Escherichia coli APEC O1 4491811 YP_854403.1 CDS gspH NC_008563.1 3382806 3383369 R type II secretion protein GspH complement(3382806..3383369) Escherichia coli APEC O1 4491812 YP_854404.1 CDS gspG NC_008563.1 3383373 3383828 R type II secretion protein GspG complement(3383373..3383828) Escherichia coli APEC O1 4491813 YP_854405.1 CDS gspF NC_008563.1 3383845 3385068 R type II secretion protein GspF complement(3383845..3385068) Escherichia coli APEC O1 4491814 YP_854406.1 CDS gspE NC_008563.1 3385068 3386561 R type II secretion protein GspE complement(3385068..3386561) Escherichia coli APEC O1 4491815 YP_854407.1 CDS gspD NC_008563.1 3386561 3388621 R type II secretion protein GspD complement(3386561..3388621) Escherichia coli APEC O1 4491816 YP_854408.1 CDS gspC NC_008563.1 3388651 3389493 R part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC complement(3388651..3389493) Escherichia coli APEC O1 4491817 YP_854410.1 CDS APECO1_3456 NC_008563.1 3389628 3390038 R hypothetical protein complement(3389628..3390038) Escherichia coli APEC O1 4491818 YP_854416.1 CDS pppA NC_008563.1 3390104 3391009 R prepilin peptidase A complement(3390104..3391009) Escherichia coli APEC O1 4491819 YP_854419.1 CDS yghJ NC_008563.1 3391077 3395639 R lipoprotein AcfD-like complement(3391077..3395639) Escherichia coli APEC O1 4491820 YP_854446.1 CDS APECO1_3453 NC_008563.1 3395790 3396095 D hypothetical protein 3395790..3396095 Escherichia coli APEC O1 4491821 YP_854447.1 CDS yghK NC_008563.1 3396123 3397805 R glycolate transporter complement(3396123..3397805) Escherichia coli APEC O1 4491822 YP_854448.1 CDS glcB NC_008563.1 3398161 3400332 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3398161..3400332) Escherichia coli APEC O1 4491823 YP_854449.1 CDS glcC NC_008563.1 3400354 3400758 R hypothetical protein complement(3400354..3400758) Escherichia coli APEC O1 4491824 YP_854450.1 CDS glcE NC_008563.1 3401997 3403049 R glycolate oxidase FAD binding subunit complement(3401997..3403049) Escherichia coli APEC O1 4491825 YP_854451.1 CDS glcD NC_008563.1 3403049 3404548 R glycolate oxidase subunit GlcD complement(3403049..3404548) Escherichia coli APEC O1 4491826 YP_854452.1 CDS glcC NC_008563.1 3404739 3405563 D DNA-binding transcriptional regulator GlcC 3404739..3405563 Escherichia coli APEC O1 4491827 YP_854453.1 CDS APECO1_3446 NC_008563.1 3405570 3406712 R hypothetical protein complement(3405570..3406712) Escherichia coli APEC O1 4491828 YP_854454.1 CDS APECO1_3445 NC_008563.1 3407083 3408807 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3407083..3408807 Escherichia coli APEC O1 4491829 YP_854455.1 CDS APECO1_3444 NC_008563.1 3408594 3409718 D hypothetical protein 3408594..3409718 Escherichia coli APEC O1 4494238 YP_854456.1 CDS APECO1_3443 NC_008563.1 3409998 3411170 D 7-keto-8-aminopelargonate synthetase and related enzymes family; hypothetical protein 3409998..3411170 Escherichia coli APEC O1 4494239 YP_854457.1 CDS APECO1_3442 NC_008563.1 3411205 3412284 R permease complement(3411205..3412284) Escherichia coli APEC O1 4494240 YP_854458.1 CDS APECO1_3441 NC_008563.1 3412281 3413351 R permease complement(3412281..3413351) Escherichia coli APEC O1 4494241 YP_854459.1 CDS ytfJ NC_008563.1 3413382 3413942 R transcriptional regulator complement(3413382..3413942) Escherichia coli APEC O1 4494242 YP_854460.1 CDS APECO1_3439 NC_008563.1 3413942 3414778 R hypothetical protein complement(3413942..3414778) Escherichia coli APEC O1 4494243 YP_854461.1 CDS yghQ NC_008563.1 3414778 3415989 R hypothetical protein complement(3414778..3415989) Escherichia coli APEC O1 4494244 YP_854462.1 CDS APECO1_3437 NC_008563.1 3416173 3416943 R hypothetical protein complement(3416173..3416943) Escherichia coli APEC O1 4494245 YP_854463.1 CDS yghS NC_008563.1 3416963 3417676 R ATP-binding protein YghS complement(3416963..3417676) Escherichia coli APEC O1 4494246 YP_854464.1 CDS yghT NC_008563.1 3417851 3418543 D nucleoside triphosphate hydrolase domain-containing protein 3417851..3418543 Escherichia coli APEC O1 4494247 YP_854465.1 CDS pitB NC_008563.1 3418592 3420091 R low-affinity inorganic phosphate transporter 2 complement(3418592..3420091) Escherichia coli APEC O1 4494248 YP_854466.1 CDS gsp NC_008563.1 3420383 3422245 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3420383..3422245) Escherichia coli APEC O1 4494249 YP_854467.1 CDS yghU NC_008563.1 3422399 3423313 D YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 3422399..3423313 Escherichia coli APEC O1 4494250 YP_854468.1 CDS hybF NC_008563.1 3423707 3424102 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3423707..3424102) Escherichia coli APEC O1 4493010 YP_854469.1 CDS hybE NC_008563.1 3424041 3424529 R hydrogenase 2-specific chaperone complement(3424041..3424529) Escherichia coli APEC O1 4493011 YP_854481.1 CDS hybD NC_008563.1 3424522 3425016 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3424522..3425016) Escherichia coli APEC O1 4493012 YP_854500.1 CDS hybC NC_008563.1 3425016 3426719 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3425016..3426719) Escherichia coli APEC O1 4493013 YP_854501.1 CDS hybB NC_008563.1 3426716 3427894 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3426716..3427894) Escherichia coli APEC O1 4493014 YP_854502.1 CDS hybA NC_008563.1 3427884 3428870 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3427884..3428870) Escherichia coli APEC O1 4493015 YP_854503.1 CDS hybO NC_008563.1 3428873 3429991 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3428873..3429991) Escherichia coli APEC O1 4493016 YP_854504.1 CDS yghW NC_008563.1 3430180 3430467 R hypothetical protein complement(3430180..3430467) Escherichia coli APEC O1 4493017 YP_854505.1 CDS APECO1_3423 NC_008563.1 3430586 3431512 R hydrolase complement(3430586..3431512) Escherichia coli APEC O1 4493018 YP_854506.1 CDS yghZ NC_008563.1 3431630 3432670 D aldo-keto reductase 3431630..3432670 Escherichia coli APEC O1 4493019 YP_854507.1 CDS yqhA NC_008563.1 3432710 3433204 R hypothetical protein complement(3432710..3433204) Escherichia coli APEC O1 4493020 YP_854508.1 CDS yghA NC_008563.1 3433392 3434279 D oxidoreductase 3433392..3434279 Escherichia coli APEC O1 4493021 YP_854509.1 CDS exbD NC_008563.1 3434318 3434743 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3434318..3434743) Escherichia coli APEC O1 4493022 YP_854510.1 CDS exbB NC_008563.1 3434750 3435484 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3434750..3435484) Escherichia coli APEC O1 4493023 YP_854511.1 CDS metC NC_008563.1 3435658 3436923 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3435658..3436923 Escherichia coli APEC O1 4493024 YP_854512.1 CDS yghB NC_008563.1 3437063 3437722 D hypothetical protein 3437063..3437722 Escherichia coli APEC O1 4493025 YP_854513.1 CDS yqhC NC_008563.1 3437762 3438829 R DNA-binding transcriptional regulator complement(3437762..3438829) Escherichia coli APEC O1 4493026 YP_854514.1 CDS yqhD NC_008563.1 3438855 3440018 D alcohol dehydrogenase 3438855..3440018 Escherichia coli APEC O1 4493027 YP_854515.1 CDS dkgA NC_008563.1 3440123 3440950 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3440123..3440950 Escherichia coli APEC O1 4493028 YP_854516.1 CDS yqhG NC_008563.1 3441150 3442076 D hypothetical protein 3441150..3442076 Escherichia coli APEC O1 4491577 YP_854517.1 CDS yqhH NC_008563.1 3442127 3442384 D outer membrane lipoprotein 3442127..3442384 Escherichia coli APEC O1 4491578 YP_854518.1 CDS ygiRQ NC_008563.1 3442426 3444645 R hypothetical protein complement(3442426..3444645) Escherichia coli APEC O1 4491579 YP_854519.1 CDS APECO1_3409 NC_008563.1 3444897 3445646 D regulator 3444897..3445646 Escherichia coli APEC O1 4491580 YP_854520.1 CDS APECO1_3408 NC_008563.1 3445969 3447441 D oxidoreductase YdfI 3445969..3447441 Escherichia coli APEC O1 4491581 YP_854521.1 CDS APECO1_3407 NC_008563.1 3447438 3448454 D zinc-type alcohol dehydrogenase-like protein YjjN 3447438..3448454 Escherichia coli APEC O1 4491582 YP_854522.1 CDS APECO1_3406 NC_008563.1 3448465 3449475 D ureidoglycolate dehydrogenase 3448465..3449475 Escherichia coli APEC O1 4491583 YP_854523.1 CDS APECO1_3405 NC_008563.1 3449548 3450531 D c4-dicarboxylate transport system binding protein 3449548..3450531 Escherichia coli APEC O1 4491584 YP_854524.1 CDS APECO1_3404 NC_008563.1 3450573 3451055 D hypothetical protein 3450573..3451055 Escherichia coli APEC O1 4491585 YP_854525.1 CDS ygiK NC_008563.1 3451066 3452370 D c4-dicarboxylate permease 3451066..3452370 Escherichia coli APEC O1 4491586 YP_854526.1 CDS sufI NC_008563.1 3452441 3453853 R repressor protein for FtsI complement(3452441..3453853) Escherichia coli APEC O1 4491587 YP_854528.1 CDS plsC NC_008563.1 3453928 3454665 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3453928..3454665) Escherichia coli APEC O1 4491588 YP_854531.1 CDS parC NC_008563.1 3454900 3457158 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3454900..3457158) Escherichia coli APEC O1 4491589 YP_854541.1 CDS ygiS NC_008563.1 3457296 3458903 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein complement(3457296..3458903) Escherichia coli APEC O1 4491590 YP_854596.1 CDS ygiV NC_008563.1 3459012 3459494 R transcriptional regulator complement(3459012..3459494) Escherichia coli APEC O1 4491591 YP_854599.1 CDS ygiW NC_008563.1 3459547 3459939 R hypothetical protein complement(3459547..3459939) Escherichia coli APEC O1 4491592 YP_854614.1 CDS ygiX NC_008563.1 3460091 3460750 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3460091..3460750 Escherichia coli APEC O1 4491593 YP_854615.1 CDS qseC NC_008563.1 3460747 3462096 D sensor protein QseC 3460747..3462096 Escherichia coli APEC O1 4491594 YP_854619.1 CDS APECO1_3394 NC_008563.1 3462142 3462474 R hypothetical protein complement(3462142..3462474) Escherichia coli APEC O1 4491595 YP_854628.1 CDS APECO1_3393 NC_008563.1 3462481 3463191 R hypothetical protein complement(3462481..3463191) Escherichia coli APEC O1 4491596 YP_854630.1 CDS APECO1_3392 NC_008563.1 3463194 3463673 R hypothetical protein complement(3463194..3463673) Escherichia coli APEC O1 4495011 YP_854632.1 CDS mdaB NC_008563.1 3463923 3464504 D modulator of drug activity B 3463923..3464504 Escherichia coli APEC O1 4495012 YP_854641.1 CDS APECO1_3389 NC_008563.1 3464894 3465781 R phosphosugar isomerase complement(3464894..3465781) Escherichia coli APEC O1 4495014 YP_854644.1 CDS APECO1_3388 NC_008563.1 3465778 3466785 R iron ABC transporter substrate-binding protein complement(3465778..3466785) Escherichia coli APEC O1 4495015 YP_854652.1 CDS APECO1_3387 NC_008563.1 3466736 3467785 R iron ABC transporter permease complement(3466736..3467785) Escherichia coli APEC O1 4495016 YP_854655.1 CDS APECO1_3386 NC_008563.1 3467782 3468765 R iron ABC transporter permease complement(3467782..3468765) Escherichia coli APEC O1 4495017 YP_854656.1 CDS fepC NC_008563.1 3468762 3469571 R ferric enterobactin transport ATP-binding protein FepC complement(3468762..3469571) Escherichia coli APEC O1 4495018 YP_854660.1 CDS APECO1_3384 NC_008563.1 3469945 3472086 D iron compound receptor 3469945..3472086 Escherichia coli APEC O1 4495019 YP_854666.1 CDS parE NC_008563.1 3472150 3474042 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3472150..3474042) Escherichia coli APEC O1 4495020 YP_854670.1 CDS yqiA NC_008563.1 3474071 3474652 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(3474071..3474652) Escherichia coli APEC O1 4495021 YP_854771.1 CDS icc NC_008563.1 3474652 3475347 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3474652..3475347) Escherichia coli APEC O1 4495022 YP_854814.1 CDS yqiB NC_008563.1 3475504 3475926 R hypothetical protein complement(3475504..3475926) Escherichia coli APEC O1 4495023 YP_854822.1 CDS nudF NC_008563.1 3475927 3476556 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF complement(3475927..3476556) Escherichia coli APEC O1 4495024 YP_854844.1 CDS tolC NC_008563.1 3476755 3478242 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3476755..3478242 Escherichia coli APEC O1 4495025 YP_854846.1 CDS APECO1_3377 NC_008563.1 3478357 3479061 D hypothetical protein 3478357..3479061 Escherichia coli APEC O1 4495026 YP_854849.1 CDS ygiC NC_008563.1 3479067 3480227 D synthetase/amidase 3479067..3480227 Escherichia coli APEC O1 4495027 YP_854851.1 CDS assT NC_008563.1 3480712 3482508 D arylsulfate sulfotransferase 3480712..3482508 Escherichia coli APEC O1 4495028 YP_854974.1 CDS APECO1_3374 NC_008563.1 3482526 3483194 D disulfide isomerase 3482526..3483194 Escherichia coli APEC O1 4495029 YP_854977.1 CDS APECO1_3373 NC_008563.1 3483209 3483880 D disulfide oxidoreductase 3483209..3483880 Escherichia coli APEC O1 4494526 YP_854981.1 CDS ygiD NC_008563.1 3483926 3484741 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3483926..3484741) Escherichia coli APEC O1 4494527 YP_854983.1 CDS ygiE NC_008563.1 3484857 3485630 D zinc transporter ZupT 3484857..3485630 Escherichia coli APEC O1 4494528 YP_855132.1 CDS APECO1_3370 NC_008563.1 3486433 3486996 D fimbrial protein 3486433..3486996 Escherichia coli APEC O1 4494529 YP_855135.1 CDS yqiG NC_008563.1 3487083 3489605 D outer membrane usher protein YqiG 3487083..3489605 Escherichia coli APEC O1 4494530 YP_855137.1 CDS yqiH NC_008563.1 3489612 3490361 D periplasmic chaperone YqiH 3489612..3490361 Escherichia coli APEC O1 4494531 YP_855140.1 CDS APECO1_3367 NC_008563.1 3490358 3491407 D Yqi fimbrial adhesin 3490358..3491407 Escherichia coli APEC O1 4494532 YP_855141.1 CDS ribB NC_008563.1 3491461 3492114 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3491461..3492114) Escherichia coli APEC O1 4494533 YP_855145.1 CDS yqiC NC_008563.1 3492428 3492787 D hypothetical protein 3492428..3492787 Escherichia coli APEC O1 4494534 YP_855154.1 CDS yqiJ NC_008563.1 3493292 3493921 D hypothetical protein 3493292..3493921 Escherichia coli APEC O1 4494535 YP_855184.1 CDS yqiK NC_008563.1 3493948 3495609 D hypothetical protein 3493948..3495609 Escherichia coli APEC O1 4494536 YP_855187.1 CDS rfaE NC_008563.1 3496028 3497461 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3496028..3497461) Escherichia coli APEC O1 4494537 YP_855254.1 CDS glnE NC_008563.1 3497509 3500421 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3497509..3500421) Escherichia coli APEC O1 4494538 YP_855256.1 CDS ygiF NC_008563.1 3500372 3501673 R adenylate cyclase complement(3500372..3501673) Escherichia coli APEC O1 4494539 YP_855259.1 CDS htrG NC_008563.1 3501915 3502535 D signal transduction protein 3501915..3502535 Escherichia coli APEC O1 4494540 YP_855260.1 CDS cca NC_008563.1 3502599 3503837 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3502599..3503837 Escherichia coli APEC O1 4494541 YP_855309.1 CDS uppP NC_008563.1 3504025 3504846 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3504025..3504846) Escherichia coli APEC O1 4494542 YP_855325.1 CDS folB NC_008563.1 3504937 3505305 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3504937..3505305) Escherichia coli APEC O1 4494543 YP_855413.1 CDS ygiH NC_008563.1 3505410 3506027 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3505410..3506027 Escherichia coli APEC O1 4494544 YP_855415.1 CDS APECO1_3354 NC_008563.1 3506040 3507026 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3506040..3507026) Escherichia coli APEC O1 4494545 YP_855419.1 CDS ttdA NC_008563.1 3507179 3508090 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3507179..3508090 Escherichia coli APEC O1 4492017 YP_855432.1 CDS ttdB NC_008563.1 3508087 3508692 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3508087..3508692 Escherichia coli APEC O1 4492018 YP_855434.1 CDS ygjE NC_008563.1 3508740 3510203 D tartrate:succinate antiporter 3508740..3510203 Escherichia coli APEC O1 4492019 YP_855494.1 CDS ygjD NC_008563.1 3510246 3511259 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3510246..3511259) Escherichia coli APEC O1 4492020 YP_855495.1 CDS dnaG NC_008563.1 3511823 3513568 D synthesizes RNA primers at the replication forks; DNA primase 3511823..3513568 Escherichia coli APEC O1 4492021 YP_855524.1 CDS rpoD NC_008563.1 3513763 3515604 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3513763..3515604 Escherichia coli APEC O1 4492022 YP_855530.1 CDS ygjF NC_008563.1 3515683 3516189 R G/U mismatch-specific DNA glycosylase complement(3515683..3516189) Escherichia coli APEC O1 4492023 YP_855628.1 CDS yqjH NC_008563.1 3516443 3517207 R siderophore interacting protein complement(3516443..3517207) Escherichia coli APEC O1 4492024 YP_858705.1 CDS yqjI NC_008563.1 3517484 3518107 D hypothetical protein 3517484..3518107 Escherichia coli APEC O1 4492025 YP_858706.1 CDS aer NC_008563.1 3518261 3519781 R aerotaxis sensor receptor, flavoprotein complement(3518261..3519781) Escherichia coli APEC O1 4492026 YP_858707.1 CDS ygjG NC_008563.1 3520088 3521578 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3520088..3521578 Escherichia coli APEC O1 4492027 YP_858709.1 CDS ebgR NC_008563.1 3522171 3523154 D DNA-binding transcriptional repressor EbgR 3522171..3523154 Escherichia coli APEC O1 4492029 YP_858710.1 CDS ebgA NC_008563.1 3523302 3526430 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3523302..3526430 Escherichia coli APEC O1 4492030 YP_858711.1 CDS ebgC NC_008563.1 3526427 3526876 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3526427..3526876 Escherichia coli APEC O1 4492031 YP_858712.1 CDS ygjI NC_008563.1 3526939 3528372 D oxidoreductase 3526939..3528372 Escherichia coli APEC O1 4492032 YP_858713.1 CDS ygjJ NC_008563.1 3528506 3529576 D hypothetical protein 3528506..3529576 Escherichia coli APEC O1 4492033 YP_858714.1 CDS ygjK NC_008563.1 3529593 3531944 D glycosyl hydrolase 3529593..3531944 Escherichia coli APEC O1 4492034 YP_858715.1 CDS ygjL NC_008563.1 3532115 3534133 D NADPH 2,4-dienoyl-CoA reductase 3532115..3534133 Escherichia coli APEC O1 4492035 YP_858716.1 CDS ygjO NC_008563.1 3534251 3535387 R ribosomal RNA small subunit methyltransferase D complement(3534251..3535387) Escherichia coli APEC O1 4494991 YP_858717.1 CDS ygjQ NC_008563.1 3536052 3536744 D hypothetical protein 3536052..3536744 Escherichia coli APEC O1 4494992 YP_858718.1 CDS ygjR NC_008563.1 3536805 3537809 D oxidoreductase 3536805..3537809 Escherichia coli APEC O1 4494993 YP_858719.1 CDS ygjT NC_008563.1 3538092 3539057 D hypothetical protein 3538092..3539057 Escherichia coli APEC O1 4494994 YP_858720.1 CDS ygjU NC_008563.1 3539381 3540625 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3539381..3540625 Escherichia coli APEC O1 4494995 YP_858721.1 CDS ygjV NC_008563.1 3540629 3541180 R hypothetical protein complement(3540629..3541180) Escherichia coli APEC O1 4494996 YP_858722.1 CDS uxaA NC_008563.1 3541263 3542750 R altronate hydrolase complement(3541263..3542750) Escherichia coli APEC O1 4494997 YP_858723.1 CDS uxaC NC_008563.1 3542765 3544177 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3542765..3544177) Escherichia coli APEC O1 4494998 YP_858724.1 CDS exuT NC_008563.1 3544540 3545958 D hexuronate transporter ExuT 3544540..3545958 Escherichia coli APEC O1 4494999 YP_858725.1 CDS exuR NC_008563.1 3546073 3546864 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3546073..3546864 Escherichia coli APEC O1 4495000 YP_858726.1 CDS APECO1_3324 NC_008563.1 3547209 3547871 D hypothetical protein 3547209..3547871 Escherichia coli APEC O1 4495001 YP_858727.1 CDS yqjB NC_008563.1 3547875 3548258 D hypothetical protein 3547875..3548258 Escherichia coli APEC O1 4495002 YP_858728.2 CDS yqjC NC_008563.1 3548405 3548773 D hypothetical protein 3548405..3548773 Escherichia coli APEC O1 4495003 YP_858729.1 CDS APECO1_3321 NC_008563.1 3549050 3549523 D hypothetical protein 3549050..3549523 Escherichia coli APEC O1 4495004 YP_858730.1 CDS yqjK NC_008563.1 3549471 3549812 D hypothetical protein 3549471..3549812 Escherichia coli APEC O1 4495005 YP_858731.1 CDS yqjF NC_008563.1 3549909 3550391 D hypothetical protein 3549909..3550391 Escherichia coli APEC O1 4495006 YP_858732.1 CDS yqjG NC_008563.1 3550461 3551447 D glutathione S-transferase 3550461..3551447 Escherichia coli APEC O1 4495007 YP_858733.1 CDS yhaH NC_008563.1 3551730 3552098 D cytochrome 3551730..3552098 Escherichia coli APEC O1 4495008 YP_858734.1 CDS yhaJ NC_008563.1 3552132 3553028 R DNA-binding transcriptional regulator complement(3552132..3553028) Escherichia coli APEC O1 4495009 YP_858735.1 CDS APECO1_3315 NC_008563.1 3553133 3553834 D pirin-related protein 3553133..3553834 Escherichia coli APEC O1 4495010 YP_858736.1 CDS yhaM NC_008563.1 3554153 3555463 R hypothetical protein complement(3554153..3555463) Escherichia coli APEC O1 4491459 YP_858737.1 CDS APECO1_3313 NC_008563.1 3555491 3556822 R amino acid permease complement(3555491..3556822) Escherichia coli APEC O1 4491460 YP_858738.1 CDS tdcG NC_008563.1 3557097 3558467 R L-serine dehydratase complement(3557097..3558467) Escherichia coli APEC O1 4491461 YP_858739.1 CDS tdcF NC_008563.1 3558533 3558970 R hypothetical protein complement(3558533..3558970) Escherichia coli APEC O1 4491462 YP_858740.1 CDS tdcE NC_008563.1 3558936 3561230 R formate acetyltransferase 3 complement(3558936..3561230) Escherichia coli APEC O1 4491463 YP_858741.1 CDS tdcD NC_008563.1 3561264 3562484 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3561264..3562484) Escherichia coli APEC O1 4491464 YP_858742.1 CDS tdcC NC_008563.1 3562498 3563829 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3562498..3563829) Escherichia coli APEC O1 4491465 YP_858743.1 CDS tdcB NC_008563.1 3563851 3564840 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3563851..3564840) Escherichia coli APEC O1 4491466 YP_858744.1 CDS tdcA NC_008563.1 3564933 3565871 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3564933..3565871) Escherichia coli APEC O1 4491467 YP_858745.1 CDS tdcR NC_008563.1 3566061 3566405 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3566061..3566405 Escherichia coli APEC O1 4491468 YP_858746.1 CDS APECO1_3304 NC_008563.1 3566924 3567451 D hypothetical protein 3566924..3567451 Escherichia coli APEC O1 4491469 YP_858747.1 CDS garK NC_008563.1 3567379 3568605 R glycerate kinase complement(3567379..3568605) Escherichia coli APEC O1 4491470 YP_858748.1 CDS garR NC_008563.1 3568621 3569520 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3568621..3569520) Escherichia coli APEC O1 4491471 YP_858749.1 CDS garL NC_008563.1 3569541 3570311 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3569541..3570311) Escherichia coli APEC O1 4491472 YP_858750.1 CDS garP NC_008563.1 3570327 3571661 R (D)-galactarate transporter complement(3570327..3571661) Escherichia coli APEC O1 4491473 YP_858751.1 CDS garD NC_008563.1 3572036 3573607 D D-galactarate dehydratase 3572036..3573607 Escherichia coli APEC O1 4491474 YP_858752.1 CDS agaR NC_008563.1 3573659 3574483 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; AgaR family transcriptional regulator complement(3573659..3574483) Escherichia coli APEC O1 4491475 YP_858753.1 CDS agaZ NC_008563.1 3574732 3576012 D tagatose 6-phosphate kinase 2 3574732..3576012 Escherichia coli APEC O1 4491476 YP_858754.1 CDS agaV NC_008563.1 3575999 3576508 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3575999..3576508 Escherichia coli APEC O1 4491477 YP_858755.1 CDS APECO1_3295 NC_008563.1 3576519 3577298 D phosphotransferase system enzyme subunit 3576519..3577298 Escherichia coli APEC O1 4494756 YP_858756.1 CDS APECO1_3294 NC_008563.1 3577288 3578166 D PTS system N-acetylgalactosamine-specific transporter subunit IID 3577288..3578166 Escherichia coli APEC O1 4494757 YP_858757.1 CDS agaF NC_008563.1 3578184 3578618 D phosphotransferase system enzyme subunit 3578184..3578618 Escherichia coli APEC O1 4494758 YP_858758.1 CDS APECO1_3292 NC_008563.1 3578594 3579748 D N-acetylgalactosamine-6-phosphate deacetylase 3578594..3579748 Escherichia coli APEC O1 4494759 YP_858759.1 CDS agaS NC_008563.1 3580097 3581251 D tagatose-6-phosphate ketose/aldose isomerase 3580097..3581251 Escherichia coli APEC O1 4494760 YP_858760.1 CDS kbaY NC_008563.1 3581264 3582124 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3581264..3582124 Escherichia coli APEC O1 4494761 YP_858761.1 CDS agaB NC_008563.1 3582291 3582767 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3582291..3582767 Escherichia coli APEC O1 4494762 YP_858762.1 CDS agaC NC_008563.1 3582806 3583609 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3582806..3583609 Escherichia coli APEC O1 4494763 YP_858763.1 CDS agaD NC_008563.1 3583518 3584390 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3583518..3584390 Escherichia coli APEC O1 4494764 YP_858764.1 CDS agaI NC_008563.1 3584391 3585158 D galactosamine-6-phosphate isomerase 3584391..3585158 Escherichia coli APEC O1 4494765 YP_858765.1 CDS yraL NC_008563.1 3585208 3586071 R methyltransferase complement(3585208..3586071) Escherichia coli APEC O1 4494766 YP_858766.1 CDS yraM NC_008563.1 3586136 3588172 D hypothetical protein 3586136..3588172 Escherichia coli APEC O1 4494767 YP_858767.1 CDS yraN NC_008563.1 3588130 3588525 D hypothetical protein 3588130..3588525 Escherichia coli APEC O1 4494768 YP_858768.1 CDS APECO1_3281 NC_008563.1 3588545 3589135 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3588545..3589135 Escherichia coli APEC O1 4494769 YP_858769.1 CDS yraP NC_008563.1 3589145 3589720 D periplasmic protein; hypothetical protein 3589145..3589720 Escherichia coli APEC O1 4494770 YP_858770.1 CDS yraQ NC_008563.1 3589833 3590873 R hypothetical protein complement(3589833..3590873) Escherichia coli APEC O1 4494771 YP_858771.1 CDS APECO1_3278 NC_008563.1 3590946 3591626 R hypothetical protein complement(3590946..3591626) Escherichia coli APEC O1 4494772 YP_858772.1 CDS APECO1_3277 NC_008563.1 3591709 3592227 D hypothetical protein 3591709..3592227 Escherichia coli APEC O1 4494773 YP_858773.1 CDS yhbP NC_008563.1 3592207 3592650 R hypothetical protein complement(3592207..3592650) Escherichia coli APEC O1 4494774 YP_858774.1 CDS yhbQ NC_008563.1 3592701 3593003 D GIY-YIG nuclease superfamily protein 3592701..3593003 Escherichia coli APEC O1 4494775 YP_858775.1 CDS yhbS NC_008563.1 3592990 3593493 R acyltransferase complement(3592990..3593493) Escherichia coli APEC O1 4492103 YP_858776.1 CDS yhbT NC_008563.1 3593487 3594011 R lipid carrier protein complement(3593487..3594011) Escherichia coli APEC O1 4492104 YP_858777.1 CDS yhbU NC_008563.1 3594220 3595215 D collagenase 3594220..3595215 Escherichia coli APEC O1 4492105 YP_858778.1 CDS yhbV NC_008563.1 3595206 3596102 D protease 3595206..3596102 Escherichia coli APEC O1 4492108 YP_858779.1 CDS yhbW NC_008563.1 3596183 3597190 D hypothetical protein 3596183..3597190 Escherichia coli APEC O1 4492109 YP_858780.1 CDS mtr NC_008563.1 3597308 3598552 R tryptophan transporter of high affinity; tryptophan permease complement(3597308..3598552) Escherichia coli APEC O1 4492110 YP_858781.1 CDS deaD NC_008563.1 3598706 3600646 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3598706..3600646) Escherichia coli APEC O1 4492111 YP_858782.1 CDS nlpI NC_008563.1 3600775 3601659 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3600775..3601659) Escherichia coli APEC O1 4492112 YP_858783.1 CDS pnp NC_008563.1 3601768 3603972 R polynucleotide phosphorylase/polyadenylase complement(3601768..3603972) Escherichia coli APEC O1 4492113 YP_858784.1 CDS rpsO NC_008563.1 3604150 3604419 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3604150..3604419) Escherichia coli APEC O1 4492114 YP_858785.1 CDS truB NC_008563.1 3604568 3605512 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3604568..3605512) Escherichia coli APEC O1 4492115 YP_858786.1 CDS rbfA NC_008563.1 3605512 3605913 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3605512..3605913) Escherichia coli APEC O1 4492116 YP_858787.1 CDS infB NC_008563.1 3606077 3608749 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3606077..3608749) Escherichia coli APEC O1 4492117 YP_858788.1 CDS nusA NC_008563.1 3608774 3610261 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3608774..3610261) Escherichia coli APEC O1 4492118 YP_858789.2 CDS yhbC NC_008563.1 3610289 3610741 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3610289..3610741) Escherichia coli APEC O1 4492119 YP_858790.1 CDS argG NC_008563.1 3611372 3612715 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3611372..3612715 Escherichia coli APEC O1 4492120 YP_858791.1 CDS yhbX NC_008563.1 3612723 3614366 R alkaline phosphatase I complement(3612723..3614366) Escherichia coli APEC O1 4492121 YP_858792.1 CDS secG NC_008563.1 3614903 3615235 R preprotein translocase subunit SecG complement(3614903..3615235) Escherichia coli APEC O1 4491324 YP_858793.1 CDS glmM NC_008563.1 3615463 3616800 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3615463..3616800) Escherichia coli APEC O1 4491325 YP_858794.1 CDS folP NC_008563.1 3616793 3617641 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3616793..3617641) Escherichia coli APEC O1 4491326 YP_858795.1 CDS hflB NC_008563.1 3617731 3619665 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3617731..3619665) Escherichia coli APEC O1 4491327 YP_858796.1 CDS rrmJ NC_008563.1 3619765 3620394 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(3619765..3620394) Escherichia coli APEC O1 4491328 YP_858797.1 CDS APECO1_3252 NC_008563.1 3620450 3620752 R hypothetical protein complement(3620450..3620752) Escherichia coli APEC O1 4491329 YP_858798.1 CDS greA NC_008563.1 3620969 3621445 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3620969..3621445) Escherichia coli APEC O1 4491330 YP_858799.1 CDS dacB NC_008563.1 3621693 3623126 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3621693..3623126 Escherichia coli APEC O1 4491331 YP_858800.1 CDS obgE NC_008563.1 3623167 3624339 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3623167..3624339) Escherichia coli APEC O1 4491332 YP_858801.1 CDS yhbE NC_008563.1 3624355 3625320 R hypothetical protein complement(3624355..3625320) Escherichia coli APEC O1 4491333 YP_858803.1 CDS ispB NC_008563.1 3626295 3627266 D octaprenyl diphosphate synthase 3626295..3627266 Escherichia coli APEC O1 4491335 YP_858804.1 CDS nlp NC_008563.1 3627499 3627777 D regulatory factor of maltose metabolism; activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3627499..3627777 Escherichia coli APEC O1 4491336 YP_858805.1 CDS murA NC_008563.1 3627825 3629084 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3627825..3629084) Escherichia coli APEC O1 4491337 YP_858806.1 CDS yrbA NC_008563.1 3629139 3629408 R DNA-binding transcriptional regulator complement(3629139..3629408) Escherichia coli APEC O1 4491338 YP_858807.1 CDS yrbC NC_008563.1 3629846 3630481 R hypothetical protein complement(3629846..3630481) Escherichia coli APEC O1 4491339 YP_858808.1 CDS yrbD NC_008563.1 3630500 3631051 R ABC-type organic solvent transporter complement(3630500..3631051) Escherichia coli APEC O1 4491340 YP_858809.1 CDS yrbE NC_008563.1 3631056 3631838 R toluene transporter subunit: permease component complement(3631056..3631838) Escherichia coli APEC O1 4491341 YP_858810.1 CDS yrbF NC_008563.1 3631846 3632655 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein complement(3631846..3632655) Escherichia coli APEC O1 4491342 YP_858811.1 CDS yrbG NC_008563.1 3632865 3633842 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3632865..3633842 Escherichia coli APEC O1 4491343 YP_858812.1 CDS kdsD NC_008563.1 3633856 3634842 D D-arabinose 5-phosphate isomerase 3633856..3634842 Escherichia coli APEC O1 4491382 YP_858813.1 CDS yrbI NC_008563.1 3634863 3635429 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3634863..3635429 Escherichia coli APEC O1 4491383 YP_858814.1 CDS APECO1_3236 NC_008563.1 3635426 3636001 D hypothetical protein 3635426..3636001 Escherichia coli APEC O1 4491384 YP_858815.1 CDS yhbN NC_008563.1 3635970 3636527 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3635970..3636527 Escherichia coli APEC O1 4491385 YP_858816.1 CDS yhbG NC_008563.1 3636534 3637259 D ABC transporter ATP-binding protein 3636534..3637259 Escherichia coli APEC O1 4491386 YP_858817.1 CDS rpoN NC_008563.1 3637307 3638740 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3637307..3638740 Escherichia coli APEC O1 4491387 YP_858818.1 CDS yhbH NC_008563.1 3638763 3639050 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3638763..3639050 Escherichia coli APEC O1 4491388 YP_858819.1 CDS ptsN NC_008563.1 3639144 3639659 D PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3639144..3639659 Escherichia coli APEC O1 4491389 YP_858820.1 CDS APECO1_3230 NC_008563.1 3639705 3640559 D hypothetical protein 3639705..3640559 Escherichia coli APEC O1 4491390 YP_858821.1 CDS ptsO NC_008563.1 3640556 3640828 D phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3640556..3640828 Escherichia coli APEC O1 4491391 YP_858822.1 CDS yrbL NC_008563.1 3641042 3641674 D hypothetical protein 3641042..3641674 Escherichia coli APEC O1 4491392 YP_858823.1 CDS mtgA NC_008563.1 3641671 3642399 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3641671..3642399) Escherichia coli APEC O1 4491393 YP_858824.1 CDS yhbL NC_008563.1 3642396 3643049 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(3642396..3643049) Escherichia coli APEC O1 4491394 YP_858825.1 CDS arcB NC_008563.1 3643279 3645615 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3643279..3645615) Escherichia coli APEC O1 4491395 YP_858826.1 CDS yhcC NC_008563.1 3645711 3646640 R Fe-S oxidoreductase complement(3645711..3646640) Escherichia coli APEC O1 4491396 YP_858827.1 CDS gltB NC_008563.1 3647207 3651775 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3647207..3651775 Escherichia coli APEC O1 4491397 YP_858828.1 CDS gltD NC_008563.1 3651788 3653206 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3651788..3653206 Escherichia coli APEC O1 4491398 YP_858829.1 CDS yhcH NC_008563.1 3653274 3653738 R hypothetical protein complement(3653274..3653738) Escherichia coli APEC O1 4491399 YP_858830.1 CDS nanK NC_008563.1 3653735 3654610 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3653735..3654610) Escherichia coli APEC O1 4491400 YP_858831.1 CDS nanE NC_008563.1 3654607 3655296 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3654607..3655296) Escherichia coli APEC O1 4494716 YP_858832.1 CDS nanT NC_008563.1 3655344 3656864 R sialic acid transporter complement(3655344..3656864) Escherichia coli APEC O1 4494717 YP_858833.1 CDS nanA NC_008563.1 3656943 3657836 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3656943..3657836) Escherichia coli APEC O1 4494718 YP_858834.1 CDS nanR NC_008563.1 3657958 3658749 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3657958..3658749) Escherichia coli APEC O1 4494719 YP_858835.1 CDS sspB NC_008563.1 3658857 3659354 R ClpXP protease specificity-enhancing factor complement(3658857..3659354) Escherichia coli APEC O1 4494720 YP_858836.1 CDS sspA NC_008563.1 3659360 3659998 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3659360..3659998) Escherichia coli APEC O1 4494721 YP_858837.1 CDS rpsI NC_008563.1 3660393 3660785 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3660393..3660785) Escherichia coli APEC O1 4494722 YP_858838.1 CDS rplM NC_008563.1 3660801 3661229 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3660801..3661229) Escherichia coli APEC O1 4494723 YP_858839.1 CDS yhcM NC_008563.1 3661449 3662576 R ATPase function; hypothetical protein complement(3661449..3662576) Escherichia coli APEC O1 4494724 YP_858840.1 CDS APECO1_3211 NC_008563.1 3662819 3663229 D hypothetical protein 3662819..3663229 Escherichia coli APEC O1 4494725 YP_858841.1 CDS degQ NC_008563.1 3663322 3664689 D serine endoprotease 3663322..3664689 Escherichia coli APEC O1 4494726 YP_858842.1 CDS degS NC_008563.1 3664779 3665846 D serine endoprotease 3664779..3665846 Escherichia coli APEC O1 4494727 YP_858843.1 CDS mdh NC_008563.1 3665909 3666847 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3665909..3666847) Escherichia coli APEC O1 4494728 YP_858844.1 CDS argR NC_008563.1 3667282 3667752 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3667282..3667752 Escherichia coli APEC O1 4494729 YP_858845.1 CDS APECO1_3206 NC_008563.1 3668065 3668379 D hypothetical protein 3668065..3668379 Escherichia coli APEC O1 4494730 YP_858846.1 CDS yhcO NC_008563.1 3668434 3668706 R hypothetical protein complement(3668434..3668706) Escherichia coli APEC O1 4494731 YP_858847.1 CDS yhcP NC_008563.1 3668798 3670765 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3668798..3670765) Escherichia coli APEC O1 4494732 YP_858848.1 CDS yhcQ NC_008563.1 3670771 3671703 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3670771..3671703) Escherichia coli APEC O1 4494733 YP_858849.2 CDS APECO1_3202 NC_008563.1 3671711 3671914 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3671711..3671914) Escherichia coli APEC O1 4494734 YP_858850.1 CDS aaeR NC_008563.1 3672097 3673026 D DNA-binding transcriptional regulator 3672097..3673026 Escherichia coli APEC O1 4494735 YP_858851.1 CDS tldD NC_008563.1 3673154 3674599 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3673154..3674599) Escherichia coli APEC O1 4493831 YP_858852.1 CDS yhdP NC_008563.1 3674755 3678555 R hypothetical protein complement(3674755..3678555) Escherichia coli APEC O1 4493832 YP_858853.1 CDS rng NC_008563.1 3678623 3680092 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3678623..3680092) Escherichia coli APEC O1 4493833 YP_858854.1 CDS maf NC_008563.1 3680082 3680675 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3680082..3680675) Escherichia coli APEC O1 4493834 YP_858855.1 CDS mreD NC_008563.1 3680684 3681172 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3680684..3681172) Escherichia coli APEC O1 4493835 YP_858856.1 CDS mreC NC_008563.1 3681172 3682275 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3681172..3682275) Escherichia coli APEC O1 4493836 YP_858857.1 CDS mreB NC_008563.1 3682341 3683384 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3682341..3683384) Escherichia coli APEC O1 4493837 YP_858858.1 CDS yhdA NC_008563.1 3683689 3685629 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3683689..3685629) Escherichia coli APEC O1 4493838 YP_858859.1 CDS yhdH NC_008563.1 3685781 3686755 D oxidoreductase, Zn-dependent and NAD(P)-binding 3685781..3686755 Escherichia coli APEC O1 4493839 YP_858860.1 CDS accB NC_008563.1 3687733 3688203 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3687733..3688203 Escherichia coli APEC O1 4493840 YP_858861.1 CDS accC NC_008563.1 3688214 3689563 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3688214..3689563 Escherichia coli APEC O1 4493841 YP_858862.1 CDS APECO1_3189 NC_008563.1 3689655 3690701 R hypothetical protein complement(3689655..3690701) Escherichia coli APEC O1 4493842 YP_858863.1 CDS APECO1_3188 NC_008563.1 3690698 3691660 R ribokinase family sugar kinase complement(3690698..3691660) Escherichia coli APEC O1 4493843 YP_858864.1 CDS rbsC NC_008563.1 3691682 3692671 R ribose transport system permease RbsC complement(3691682..3692671) Escherichia coli APEC O1 4493844 YP_858865.1 CDS rbsA NC_008563.1 3692672 3694171 R ribose transport ATP-binding protein RbsA complement(3692672..3694171) Escherichia coli APEC O1 4493845 YP_858866.1 CDS APECO1_3185 NC_008563.1 3694232 3695122 R ribose ABC transporter complement(3694232..3695122) Escherichia coli APEC O1 4493846 YP_858867.1 CDS gatY NC_008563.1 3695158 3696012 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(3695158..3696012) Escherichia coli APEC O1 4493847 YP_858868.1 CDS APECO1_3183 NC_008563.1 3696353 3697183 D DeoR family transcriptional regulator 3696353..3697183 Escherichia coli APEC O1 4493848 YP_858869.1 CDS APECO1_31822 NC_008563.1 3697140 3697790 D hypothetical protein 3697140..3697790 Escherichia coli APEC O1 4493849 YP_858870.1 CDS APECO1_3182 NC_008563.1 3697869 3698150 D hypothetical protein 3697869..3698150 Escherichia coli APEC O1 4491869 YP_858871.1 CDS yhdT NC_008563.1 3698225 3698485 D hypothetical protein 3698225..3698485 Escherichia coli APEC O1 4491870 YP_858872.1 CDS panF NC_008563.1 3698469 3699926 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3698469..3699926 Escherichia coli APEC O1 4491871 YP_858873.1 CDS prmA NC_008563.1 3699938 3700819 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3699938..3700819 Escherichia coli APEC O1 4491872 YP_858874.1 CDS dusB NC_008563.1 3701148 3702113 D tRNA-dihydrouridine synthase B 3701148..3702113 Escherichia coli APEC O1 4491873 YP_858875.1 CDS fis NC_008563.1 3702139 3702435 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3702139..3702435 Escherichia coli APEC O1 4491874 YP_858876.1 CDS yhdJ NC_008563.1 3702523 3703407 D methyltransferase 3702523..3703407 Escherichia coli APEC O1 4491875 YP_858877.1 CDS envR NC_008563.1 3703673 3704335 R DNA-binding transcriptional regulator EnvR complement(3703673..3704335) Escherichia coli APEC O1 4491876 YP_858878.1 CDS acrE NC_008563.1 3704734 3705891 D acriflavine resistance protein E 3704734..3705891 Escherichia coli APEC O1 4491877 YP_858879.1 CDS acrF NC_008563.1 3705903 3709007 D acriflavine resistance protein F 3705903..3709007 Escherichia coli APEC O1 4491878 YP_858880.1 CDS yhdW NC_008563.1 3709912 3710937 D periplasmic amino acid ABC transporter binding protein 3709912..3710937 Escherichia coli APEC O1 4491879 YP_858881.1 CDS yhdX NC_008563.1 3710987 3712186 D amino acid ABC transporter permease 3710987..3712186 Escherichia coli APEC O1 4491880 YP_858882.1 CDS yhdY NC_008563.1 3712193 3713299 D transport system permease 3712193..3713299 Escherichia coli APEC O1 4491881 YP_858883.1 CDS yhdZ NC_008563.1 3713307 3714065 D amino acid ABC transporter ATP-binding protein 3713307..3714065 Escherichia coli APEC O1 4491882 YP_858886.1 CDS APECO1_3166 NC_008563.1 3719736 3720506 D hypothetical protein 3719736..3720506 Escherichia coli APEC O1 4491885 YP_858887.1 CDS aroE NC_008563.1 3720736 3721554 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3720736..3721554) Escherichia coli APEC O1 4491886 YP_858888.1 CDS yrdC NC_008563.1 3721559 3722176 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3721559..3722176) Escherichia coli APEC O1 4491887 YP_858889.1 CDS yrdD NC_008563.1 3722136 3722678 R DNA topoisomerase complement(3722136..3722678) Escherichia coli APEC O1 4491888 YP_858890.1 CDS APECO1_3162 NC_008563.1 3722707 3723180 R hypothetical protein complement(3722707..3723180) Escherichia coli APEC O1 4491715 YP_858891.1 CDS APECO1_3161 NC_008563.1 3723152 3724276 R DNA protecting protein DprA complement(3723152..3724276) Escherichia coli APEC O1 4491716 YP_858892.1 CDS def NC_008563.1 3724406 3724915 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3724406..3724915 Escherichia coli APEC O1 4491717 YP_858893.1 CDS fmt NC_008563.1 3724930 3725877 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3724930..3725877 Escherichia coli APEC O1 4491718 YP_858894.1 CDS sun NC_008563.1 3725929 3727218 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3725929..3727218 Escherichia coli APEC O1 4491719 YP_858895.1 CDS trkA NC_008563.1 3727240 3728616 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3727240..3728616 Escherichia coli APEC O1 4491720 YP_858896.1 CDS mscL NC_008563.1 3728746 3729159 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3728746..3729159 Escherichia coli APEC O1 4491721 YP_858897.1 CDS zntR NC_008563.1 3729430 3729855 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3729430..3729855) Escherichia coli APEC O1 4491722 YP_858898.1 CDS yhdN NC_008563.1 3729866 3730234 R hypothetical protein complement(3729866..3730234) Escherichia coli APEC O1 4491723 YP_858899.1 CDS rplQ NC_008563.1 3730341 3730724 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3730341..3730724) Escherichia coli APEC O1 4491724 YP_858900.1 CDS rpoA NC_008563.1 3730765 3731754 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3730765..3731754) Escherichia coli APEC O1 4491725 YP_858901.1 CDS rpsD NC_008563.1 3731780 3732400 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3731780..3732400) Escherichia coli APEC O1 4491726 YP_858902.1 CDS rpsK NC_008563.1 3732434 3732823 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3732434..3732823) Escherichia coli APEC O1 4491727 YP_858903.1 CDS rpsM NC_008563.1 3732840 3733196 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3732840..3733196) Escherichia coli APEC O1 4491728 YP_858904.1 CDS secY NC_008563.1 3733491 3734822 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3733491..3734822) Escherichia coli APEC O1 4491729 YP_858905.1 CDS rplO NC_008563.1 3734830 3735264 R late assembly protein; 50S ribosomal protein L15 complement(3734830..3735264) Escherichia coli APEC O1 4491730 YP_858906.1 CDS rpsE NC_008563.1 3735451 3735954 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3735451..3735954) Escherichia coli APEC O1 4491733 YP_858907.1 CDS rplR NC_008563.1 3735969 3736322 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3735969..3736322) Escherichia coli APEC O1 4493722 YP_858908.1 CDS rplF NC_008563.1 3736332 3736865 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3736332..3736865) Escherichia coli APEC O1 4493723 YP_858909.1 CDS rpsH NC_008563.1 3736878 3737270 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3736878..3737270) Escherichia coli APEC O1 4493724 YP_858910.1 CDS rpsN NC_008563.1 3737304 3737609 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3737304..3737609) Escherichia coli APEC O1 4493725 YP_858911.1 CDS rplE NC_008563.1 3737624 3738163 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3737624..3738163) Escherichia coli APEC O1 4493726 YP_858912.1 CDS rplX NC_008563.1 3738178 3738492 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3738178..3738492) Escherichia coli APEC O1 4493727 YP_858913.1 CDS rplN NC_008563.1 3738503 3738874 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3738503..3738874) Escherichia coli APEC O1 4493728 YP_858914.1 CDS rpsQ NC_008563.1 3739039 3739293 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3739039..3739293) Escherichia coli APEC O1 4493729 YP_858915.1 CDS rplP NC_008563.1 3739484 3739894 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3739484..3739894) Escherichia coli APEC O1 4493730 YP_858916.1 CDS rpsC NC_008563.1 3739907 3740608 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3739907..3740608) Escherichia coli APEC O1 4493731 YP_858917.1 CDS rplV NC_008563.1 3740626 3740958 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3740626..3740958) Escherichia coli APEC O1 4493732 YP_858918.1 CDS rpsS NC_008563.1 3740973 3741251 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3740973..3741251) Escherichia coli APEC O1 4493733 YP_858919.1 CDS rplB NC_008563.1 3741268 3742089 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3741268..3742089) Escherichia coli APEC O1 4494796 YP_858920.1 CDS rplD NC_008563.1 3742406 3743011 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3742406..3743011) Escherichia coli APEC O1 4494797 YP_858921.1 CDS rplC NC_008563.1 3743022 3743651 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3743022..3743651) Escherichia coli APEC O1 4494798 YP_858922.1 CDS rpsJ NC_008563.1 3743684 3743995 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3743684..3743995) Escherichia coli APEC O1 4494799 YP_858923.1 CDS yheD NC_008563.1 3744654 3745229 R general secretion pathway protein A complement(3744654..3745229) Escherichia coli APEC O1 4494800 YP_858924.1 CDS yheD NC_008563.1 3745160 3745831 R general secretion pathway protein A complement(3745160..3745831) Escherichia coli APEC O1 4494801 YP_858925.1 CDS hofC NC_008563.1 3746321 3747136 D general secretion pathway protein C 3746321..3747136 Escherichia coli APEC O1 4494802 YP_858926.1 CDS hofD NC_008563.1 3747108 3749072 D general secretion pathway protein D 3747108..3749072 Escherichia coli APEC O1 4494803 YP_858927.1 CDS hofE NC_008563.1 3749580 3750563 D general secretion pathway protein E 3749580..3750563 Escherichia coli APEC O1 4494804 YP_858928.1 CDS hofF NC_008563.1 3750560 3751756 D general secretion pathway protein F 3750560..3751756 Escherichia coli APEC O1 4494805 YP_858929.1 CDS hofG NC_008563.1 3751766 3752203 D general secretion pathway protein G 3751766..3752203 Escherichia coli APEC O1 4494806 YP_858930.1 CDS hofH NC_008563.1 3752211 3752720 D general secretion pathway protein H 3752211..3752720 Escherichia coli APEC O1 4494807 YP_858931.1 CDS hofI NC_008563.1 3752678 3753112 D general secretion pathway protein I 3752678..3753112 Escherichia coli APEC O1 4494808 YP_858932.1 CDS hofJ NC_008563.1 3753105 3753692 D general secretion pathway protein J 3753105..3753692 Escherichia coli APEC O1 4494809 YP_858933.1 CDS hofK NC_008563.1 3753685 3753975 D general secretion pathway protein K 3753685..3753975 Escherichia coli APEC O1 4494810 YP_858934.1 CDS hofK NC_008563.1 3754120 3754671 D general secretion pathway protein K 3754120..3754671 Escherichia coli APEC O1 4494811 YP_858935.1 CDS yheK NC_008563.1 3754686 3755849 D general secretion pathway protein L 3754686..3755849 Escherichia coli APEC O1 4494812 YP_858936.1 CDS pshM NC_008563.1 3755822 3756307 D general secretion pathway protein M 3755822..3756307 Escherichia coli APEC O1 4494813 YP_858937.1 CDS hofD NC_008563.1 3756307 3756984 D type 4 prepilin-like proteins leader peptide processing enzyme 3756307..3756984 Escherichia coli APEC O1 4494814 YP_858938.1 CDS bfr NC_008563.1 3757013 3757489 R iron storage protein; bacterioferritin complement(3757013..3757489) Escherichia coli APEC O1 4494121 YP_858939.1 CDS yheB NC_008563.1 3757924 3760581 R bifunctional chitinase/lysozyme complement(3757924..3760581) Escherichia coli APEC O1 4494122 YP_858940.2 CDS tufA NC_008563.1 3760928 3762112 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3760928..3762112) Escherichia coli APEC O1 4494123 YP_858941.1 CDS fusA NC_008563.1 3762183 3764297 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3762183..3764297) Escherichia coli APEC O1 4494124 YP_858942.1 CDS rpsG NC_008563.1 3764394 3764864 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3764394..3764864) Escherichia coli APEC O1 4494125 YP_858943.1 CDS rpsL NC_008563.1 3764961 3765335 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3764961..3765335) Escherichia coli APEC O1 4494126 YP_858944.1 CDS yheL NC_008563.1 3765461 3765748 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3765461..3765748) Escherichia coli APEC O1 4494127 YP_858945.1 CDS yheM NC_008563.1 3765755 3766114 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3765755..3766114) Escherichia coli APEC O1 4494128 YP_858946.1 CDS yheN NC_008563.1 3766114 3766500 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3766114..3766500) Escherichia coli APEC O1 4494129 YP_858947.1 CDS yheO NC_008563.1 3766500 3767234 R hypothetical protein complement(3766500..3767234) Escherichia coli APEC O1 4494130 YP_858948.1 CDS fkpA NC_008563.1 3767389 3768201 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3767389..3768201) Escherichia coli APEC O1 4494131 YP_858949.1 CDS slyD NC_008563.1 3768689 3769279 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3768689..3769279) Escherichia coli APEC O1 4494132 YP_858950.1 CDS kefB NC_008563.1 3769584 3771389 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3769584..3771389) Escherichia coli APEC O1 4494133 YP_858951.1 CDS yheR NC_008563.1 3771389 3771943 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3771389..3771943) Escherichia coli APEC O1 4494134 YP_858952.1 CDS yheS NC_008563.1 3772071 3773984 D ABC transporter ATP-binding protein 3772071..3773984 Escherichia coli APEC O1 4494135 YP_858953.1 CDS yheT NC_008563.1 3773984 3775006 D hydrolase 3773984..3775006 Escherichia coli APEC O1 4494136 YP_858954.1 CDS prkB NC_008563.1 3775272 3776141 D phosphoribulokinase PrkB 3775272..3776141 Escherichia coli APEC O1 4494137 YP_858955.1 CDS APECO1_3099 NC_008563.1 3776196 3776600 R hypothetical protein complement(3776196..3776600) Escherichia coli APEC O1 4494138 YP_858956.1 CDS crp NC_008563.1 3776902 3777534 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3776902..3777534 Escherichia coli APEC O1 4494139 YP_858957.1 CDS yhfK NC_008563.1 3777585 3779675 D integral membrane protein; hypothetical protein 3777585..3779675 Escherichia coli APEC O1 4493147 YP_858958.1 CDS argD NC_008563.1 3779742 3780962 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(3779742..3780962) Escherichia coli APEC O1 4493148 YP_858959.1 CDS pabA NC_008563.1 3781048 3781611 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3781048..3781611) Escherichia coli APEC O1 4493149 YP_858960.1 CDS fic NC_008563.1 3781643 3782245 R cell filamentation protein Fic complement(3781643..3782245) Escherichia coli APEC O1 4493150 YP_858961.1 CDS ppiA NC_008563.1 3782507 3783079 R peptidyl-prolyl cis-trans isomerase A complement(3782507..3783079) Escherichia coli APEC O1 4493151 YP_858962.1 CDS yhfC NC_008563.1 3783349 3784530 D hypothetical protein 3783349..3784530 Escherichia coli APEC O1 4493152 YP_858963.1 CDS nirB NC_008563.1 3784792 3787335 D nitrite reductase, large subunit, NAD(P)H-binding 3784792..3787335 Escherichia coli APEC O1 4493153 YP_858964.1 CDS nirD NC_008563.1 3787332 3787658 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3787332..3787658 Escherichia coli APEC O1 4493154 YP_858965.1 CDS nirC NC_008563.1 3787784 3788590 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3787784..3788590 Escherichia coli APEC O1 4493155 YP_858966.1 CDS cysG NC_008563.1 3788609 3789982 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3788609..3789982 Escherichia coli APEC O1 4493156 YP_858967.1 CDS yhfS NC_008563.1 3790509 3791594 R hypothetical protein complement(3790509..3791594) Escherichia coli APEC O1 4493157 YP_858968.1 CDS yhfT NC_008563.1 3791606 3792910 R hypothetical protein complement(3791606..3792910) Escherichia coli APEC O1 4493158 YP_858969.1 CDS yhfU NC_008563.1 3792922 3793275 R hypothetical protein complement(3792922..3793275) Escherichia coli APEC O1 4493159 YP_858970.1 CDS php NC_008563.1 3793286 3794164 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3793286..3794164) Escherichia coli APEC O1 4493160 YP_858971.1 CDS yhfW NC_008563.1 3794161 3795387 R mutase complement(3794161..3795387) Escherichia coli APEC O1 4493161 YP_858972.1 CDS yhfX NC_008563.1 3795388 3796551 R amino acid racemase complement(3795388..3796551) Escherichia coli APEC O1 4493162 YP_858973.1 CDS yhfY NC_008563.1 3796635 3796997 R hypothetical protein complement(3796635..3796997) Escherichia coli APEC O1 4493163 YP_858974.1 CDS yhfZ NC_008563.1 3797014 3797919 R hypothetical protein complement(3797014..3797919) Escherichia coli APEC O1 4493164 YP_858975.1 CDS trpS NC_008563.1 3798079 3799083 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3798079..3799083) Escherichia coli APEC O1 4492162 YP_858976.1 CDS gph NC_008563.1 3799076 3799834 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3799076..3799834) Escherichia coli APEC O1 4492163 YP_858977.1 CDS rpe NC_008563.1 3799827 3800504 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3799827..3800504) Escherichia coli APEC O1 4492164 YP_858978.1 CDS dam NC_008563.1 3800522 3801358 R DNA adenine methylase complement(3800522..3801358) Escherichia coli APEC O1 4492165 YP_858979.1 CDS damX NC_008563.1 3801465 3802751 R hypothetical protein complement(3801465..3802751) Escherichia coli APEC O1 4492166 YP_858980.1 CDS aroB NC_008563.1 3802843 3803931 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3802843..3803931) Escherichia coli APEC O1 4492167 YP_858981.2 CDS aroK NC_008563.1 3803988 3804509 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3803988..3804509) Escherichia coli APEC O1 4492168 YP_858982.1 CDS hofQ NC_008563.1 3804910 3806148 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3804910..3806148) Escherichia coli APEC O1 4492169 YP_858983.1 CDS yrfB NC_008563.1 3806454 3806894 R hypothetical protein complement(3806454..3806894) Escherichia coli APEC O1 4492170 YP_858984.1 CDS yrfC NC_008563.1 3806878 3807417 R hypothetical protein complement(3806878..3807417) Escherichia coli APEC O1 4492171 YP_858985.1 CDS yrfD NC_008563.1 3807417 3808223 R hypothetical protein complement(3807417..3808223) Escherichia coli APEC O1 4492172 YP_858986.2 CDS mrcA NC_008563.1 3808316 3810868 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3808316..3810868 Escherichia coli APEC O1 4492173 YP_858987.1 CDS nudE NC_008563.1 3811034 3811594 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3811034..3811594) Escherichia coli APEC O1 4492174 YP_858988.1 CDS yrfF NC_008563.1 3811914 3814049 D protein IgaA-like membrane protein 3811914..3814049 Escherichia coli APEC O1 4492175 YP_858989.1 CDS yrfG NC_008563.1 3814069 3814782 D hydrolase 3814069..3814782 Escherichia coli APEC O1 4492176 YP_858990.1 CDS hslR NC_008563.1 3814793 3815194 D ribosome-associated heat shock protein Hsp15 3814793..3815194 Escherichia coli APEC O1 4492177 YP_858991.1 CDS hslO NC_008563.1 3815213 3816097 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3815213..3816097 Escherichia coli APEC O1 4492178 YP_858992.1 CDS yhgE NC_008563.1 3816160 3817884 R inner membrane transport protein complement(3816160..3817884) Escherichia coli APEC O1 4492179 YP_858993.1 CDS pckA NC_008563.1 3818263 3819885 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3818263..3819885 Escherichia coli APEC O1 4492180 YP_858994.1 CDS envZ NC_008563.1 3819961 3821313 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3819961..3821313) Escherichia coli APEC O1 4492181 YP_858995.1 CDS ompR NC_008563.1 3821310 3822029 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3821310..3822029) Escherichia coli APEC O1 4492601 YP_858996.1 CDS greB NC_008563.1 3822257 3822733 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3822257..3822733 Escherichia coli APEC O1 4492602 YP_858997.1 CDS yhgF NC_008563.1 3822830 3825151 D transcriptional accessory protein 3822830..3825151 Escherichia coli APEC O1 4492603 YP_858998.1 CDS feoB NC_008563.1 3825823 3828156 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3825823..3828156 Escherichia coli APEC O1 4492604 YP_858999.1 CDS yhgA NC_008563.1 3828606 3829499 D hypothetical protein 3828606..3829499 Escherichia coli APEC O1 4492605 YP_859000.1 CDS bioH NC_008563.1 3829719 3830489 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3829719..3830489) Escherichia coli APEC O1 4492606 YP_859001.1 CDS yhgH NC_008563.1 3830479 3831210 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3830479..3831210 Escherichia coli APEC O1 4492607 YP_859002.1 CDS APECO1_3052 NC_008563.1 3831269 3831844 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3831269..3831844 Escherichia coli APEC O1 4492608 YP_859003.1 CDS gntT NC_008563.1 3832205 3833521 D high-affinity transport permease for gluconate 3832205..3833521 Escherichia coli APEC O1 4492609 YP_859004.1 CDS malQ NC_008563.1 3833566 3835650 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3833566..3835650) Escherichia coli APEC O1 4492610 YP_859005.1 CDS malP NC_008563.1 3835660 3838053 R maltodextrin phosphorylase MalP complement(3835660..3838053) Escherichia coli APEC O1 4492611 YP_859006.1 CDS malT NC_008563.1 3838676 3841381 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3838676..3841381 Escherichia coli APEC O1 4492612 YP_859007.1 CDS rtcA NC_008563.1 3841424 3842443 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3841424..3842443) Escherichia coli APEC O1 4492613 YP_859008.1 CDS rtcB NC_008563.1 3842444 3843670 R hypothetical protein complement(3842444..3843670) Escherichia coli APEC O1 4492614 YP_859009.1 CDS rtcR NC_008563.1 3843859 3845418 D transcriptional regulatory protein RtcR 3843859..3845418 Escherichia coli APEC O1 4492615 YP_859010.1 CDS glpR NC_008563.1 3845438 3846232 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3845438..3846232) Escherichia coli APEC O1 4492616 YP_859011.1 CDS glpG NC_008563.1 3846213 3847043 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3846213..3847043) Escherichia coli APEC O1 4492617 YP_859012.1 CDS glpE NC_008563.1 3847088 3847414 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3847088..3847414) Escherichia coli APEC O1 4492618 YP_859013.1 CDS glpD NC_008563.1 3847604 3849109 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3847604..3849109 Escherichia coli APEC O1 4492619 YP_859014.1 CDS APECO1_3040 NC_008563.1 3849163 3849768 R hypothetical protein complement(3849163..3849768) Escherichia coli APEC O1 4492698 YP_859015.1 CDS APECO1_3039 NC_008563.1 3849771 3850538 R hypothetical protein complement(3849771..3850538) Escherichia coli APEC O1 4492699 YP_859016.1 CDS aufG NC_008563.1 3850541 3851251 R hypothetical protein complement(3850541..3851251) Escherichia coli APEC O1 4492700 YP_859017.1 CDS APECO1_3037 NC_008563.1 3851424 3852545 R fimbrial adhesin complement(3851424..3852545) Escherichia coli APEC O1 4492701 YP_859018.1 CDS aufF NC_008563.1 3852560 3852892 R Auf fimbrial chaperone AufF complement(3852560..3852892) Escherichia coli APEC O1 4492702 YP_859019.1 CDS aufF NC_008563.1 3853030 3853368 R Auf fimbrial chaperone AufF complement(3853030..3853368) Escherichia coli APEC O1 4492703 YP_859020.1 CDS aufE NC_008563.1 3853375 3853890 R Auf fimbriae minor subunit AufE complement(3853375..3853890) Escherichia coli APEC O1 4492704 YP_859021.1 CDS aufD NC_008563.1 3853835 3854407 R Auf fimbriae minor subunit AufD complement(3853835..3854407) Escherichia coli APEC O1 4492705 YP_859022.1 CDS aufC NC_008563.1 3854398 3856992 R outer membrane usher protein AufC complement(3854398..3856992) Escherichia coli APEC O1 4492706 YP_859023.1 CDS APECO1_3031 NC_008563.1 3857029 3857808 R fimbrial chaperone protein complement(3857029..3857808) Escherichia coli APEC O1 4492707 YP_859024.1 CDS aufA NC_008563.1 3857882 3858586 R Auf fimbriae major subunit AufA complement(3857882..3858586) Escherichia coli APEC O1 4492708 YP_859025.1 CDS glgP NC_008563.1 3859080 3861527 R glycogen phosphorylase GlgP complement(3859080..3861527) Escherichia coli APEC O1 4492709 YP_859026.1 CDS glgA NC_008563.1 3861546 3862979 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3861546..3862979) Escherichia coli APEC O1 4492710 YP_859027.1 CDS glgC NC_008563.1 3862979 3864310 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3862979..3864310) Escherichia coli APEC O1 4492711 YP_859028.1 CDS glgX NC_008563.1 3864292 3866265 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3864292..3866265) Escherichia coli APEC O1 4492712 YP_859029.1 CDS glgB NC_008563.1 3866262 3868448 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3866262..3868448) Escherichia coli APEC O1 4492713 YP_859030.1 CDS asd NC_008563.1 3868721 3869884 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3868721..3869884) Escherichia coli APEC O1 4492714 YP_859031.1 CDS yhgN NC_008563.1 3870016 3870609 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3870016..3870609 Escherichia coli APEC O1 4492715 YP_859032.1 CDS gntU NC_008563.1 3870666 3871733 R gluconate transporter GntU, low affinity GNT 1 system complement(3870666..3871733) Escherichia coli APEC O1 4492716 YP_859033.1 CDS gntK NC_008563.1 3872013 3872501 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3872013..3872501) Escherichia coli APEC O1 4492717 YP_859034.1 CDS gntR NC_008563.1 3872679 3873674 R DNA-binding transcriptional repressor complement(3872679..3873674) Escherichia coli APEC O1 4495191 YP_859035.1 CDS yhhW NC_008563.1 3873767 3874462 R hypothetical protein complement(3873767..3874462) Escherichia coli APEC O1 4495192 YP_859036.1 CDS yhhX NC_008563.1 3874585 3875622 R dehydrogenase complement(3874585..3875622) Escherichia coli APEC O1 4495193 YP_859037.1 CDS APECO1_3017 NC_008563.1 3875679 3875933 R hypothetical protein complement(3875679..3875933) Escherichia coli APEC O1 4495194 YP_859038.1 CDS yhhY NC_008563.1 3875956 3876444 D YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3875956..3876444 Escherichia coli APEC O1 4495195 YP_859039.1 CDS yhhZ NC_008563.1 3876680 3877480 D hypothetical protein 3876680..3877480 Escherichia coli APEC O1 4495196 YP_859040.1 CDS yrhA NC_008563.1 3877855 3878349 D hypothetical protein 3877855..3878349 Escherichia coli APEC O1 4495197 YP_859041.1 CDS yrhB NC_008563.1 3878799 3879083 D hypothetical protein 3878799..3879083 Escherichia coli APEC O1 4495198 YP_859042.1 CDS ggt NC_008563.1 3879121 3880854 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3879121..3880854) Escherichia coli APEC O1 4495199 YP_859043.1 CDS yhhA NC_008563.1 3880974 3881414 D hypothetical protein 3880974..3881414 Escherichia coli APEC O1 4495200 YP_859044.1 CDS ugpQ NC_008563.1 3881401 3882144 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3881401..3882144) Escherichia coli APEC O1 4495201 YP_859045.1 CDS ugpC NC_008563.1 3882141 3883211 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3882141..3883211) Escherichia coli APEC O1 4495202 YP_859046.1 CDS ugpE NC_008563.1 3883213 3884058 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3883213..3884058) Escherichia coli APEC O1 4495203 YP_859047.1 CDS ugpA NC_008563.1 3884055 3884942 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3884055..3884942) Escherichia coli APEC O1 4495204 YP_859048.1 CDS ugpB NC_008563.1 3885040 3886356 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3885040..3886356) Escherichia coli APEC O1 4495205 YP_859049.1 CDS livF NC_008563.1 3886753 3887478 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3886753..3887478) Escherichia coli APEC O1 4495206 YP_859050.1 CDS livG NC_008563.1 3887468 3888235 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3887468..3888235) Escherichia coli APEC O1 4495207 YP_859051.1 CDS livM NC_008563.1 3888232 3889509 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3888232..3889509) Escherichia coli APEC O1 4495208 YP_859052.1 CDS livH NC_008563.1 3889506 3890432 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3889506..3890432) Escherichia coli APEC O1 4495209 YP_859053.1 CDS livK NC_008563.1 3890480 3891589 R leucine transporter subunit complement(3890480..3891589) Escherichia coli APEC O1 4494677 YP_859054.1 CDS yhhK NC_008563.1 3892013 3892396 D hypothetical protein 3892013..3892396 Escherichia coli APEC O1 4494678 YP_859055.1 CDS livJ NC_008563.1 3892584 3893744 R Leu/Ile/Val-binding protein precursor complement(3892584..3893744) Escherichia coli APEC O1 4494679 YP_859056.1 CDS APECO1_2998 NC_008563.1 3894691 3895023 D PTS system component; hypothetical protein 3894691..3895023 Escherichia coli APEC O1 4494680 YP_859057.1 CDS APECO1_2997 NC_008563.1 3895030 3895515 D PTS system component; hypothetical protein 3895030..3895515 Escherichia coli APEC O1 4494681 YP_859058.1 CDS APECO1_2996 NC_008563.1 3895532 3896278 D hypothetical protein 3895532..3896278 Escherichia coli APEC O1 4494682 YP_859059.1 CDS APECO1_2995 NC_008563.1 3896223 3897125 D phosphotransferase system enzyme II; hypothetical protein 3896223..3897125 Escherichia coli APEC O1 4494683 YP_859060.1 CDS APECO1_2994 NC_008563.1 3897417 3898055 D similar to D-3-phosphoglycerate dehydrogenase; hypothetical protein 3897417..3898055 Escherichia coli APEC O1 4494684 YP_859061.1 CDS APECO1_2993 NC_008563.1 3898055 3898939 D hypothetical protein 3898055..3898939 Escherichia coli APEC O1 4494685 YP_859062.1 CDS rpoH NC_008563.1 3899043 3899897 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3899043..3899897) Escherichia coli APEC O1 4494686 YP_859063.1 CDS ftsX NC_008563.1 3900142 3901227 R ABC transporter membrane protein; cell division protein FtsX complement(3900142..3901227) Escherichia coli APEC O1 4494687 YP_859064.1 CDS ftsE NC_008563.1 3901193 3901861 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3901193..3901861) Escherichia coli APEC O1 4494688 YP_859065.1 CDS ftsY NC_008563.1 3901864 3903360 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3901864..3903360) Escherichia coli APEC O1 4494689 YP_859066.1 CDS rsmD NC_008563.1 3903510 3904106 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3903510..3904106 Escherichia coli APEC O1 4494690 YP_859067.1 CDS yhhM NC_008563.1 3904368 3904727 R hypothetical protein complement(3904368..3904727) Escherichia coli APEC O1 4494691 YP_859068.1 CDS yhhN NC_008563.1 3904868 3905494 D inner membrane protein; hypothetical protein 3904868..3905494 Escherichia coli APEC O1 4494692 YP_859069.1 CDS zntA NC_008563.1 3905568 3907766 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3905568..3907766 Escherichia coli APEC O1 4494693 YP_859071.1 CDS yhhQ NC_008563.1 3908501 3909166 D hypothetical protein 3908501..3909166 Escherichia coli APEC O1 4494695 YP_859072.1 CDS APECO1_2982 NC_008563.1 3909197 3909796 D hypothetical protein 3909197..3909796 Escherichia coli APEC O1 4494696 YP_859073.2 CDS yhhS NC_008563.1 3909800 3911017 R major facilitator superfamily transporter complement(3909800..3911017) Escherichia coli APEC O1 4495327 YP_859074.1 CDS yhhT NC_008563.1 3911149 3912198 D hypothetical protein 3911149..3912198 Escherichia coli APEC O1 4495328 YP_859075.1 CDS acpT NC_008563.1 3912253 3912840 D holo-(acyl carrier protein) synthase 2 3912253..3912840 Escherichia coli APEC O1 4495329 YP_859076.1 CDS nikA NC_008563.1 3912951 3914525 D nickel-binding periplasmic protein NikA 3912951..3914525 Escherichia coli APEC O1 4495330 YP_859077.1 CDS nikB NC_008563.1 3914525 3915469 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3914525..3915469 Escherichia coli APEC O1 4495331 YP_859078.1 CDS nikC NC_008563.1 3915466 3916299 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3915466..3916299 Escherichia coli APEC O1 4495332 YP_859079.1 CDS nikD NC_008563.1 3916299 3917063 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3916299..3917063 Escherichia coli APEC O1 4495333 YP_859080.1 CDS nikE NC_008563.1 3917060 3917866 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3917060..3917866 Escherichia coli APEC O1 4495334 YP_859081.1 CDS nikR NC_008563.1 3917872 3918273 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3917872..3918273 Escherichia coli APEC O1 4495335 YP_859082.1 CDS APECO1_2972 NC_008563.1 3918463 3919218 D regulatory protein 3918463..3919218 Escherichia coli APEC O1 4495336 YP_859083.1 CDS APECO1_2971 NC_008563.1 3919243 3919716 D phosphotransferase system enzyme subunit 3919243..3919716 Escherichia coli APEC O1 4495337 YP_859084.1 CDS APECO1_2970 NC_008563.1 3919713 3919994 D phosphotransferase system enzyme subunit 3919713..3919994 Escherichia coli APEC O1 4495338 YP_859085.1 CDS APECO1_2969 NC_008563.1 3920041 3921429 D PTS system galactitol-specific transporter subunit IIC 3920041..3921429 Escherichia coli APEC O1 4495339 YP_859086.1 CDS APECO1_2968 NC_008563.1 3921422 3922930 D xylulose kinase 3921422..3922930 Escherichia coli APEC O1 4495340 YP_859087.1 CDS APECO1_2967 NC_008563.1 3922920 3923189 D phosphotransferase system HPr enzyme 3922920..3923189 Escherichia coli APEC O1 4495341 YP_859088.1 CDS gatY NC_008563.1 3923221 3924072 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3923221..3924072 Escherichia coli APEC O1 4495342 YP_859089.1 CDS yhhJ NC_008563.1 3924182 3925306 R ABC transporter membrane protein complement(3924182..3925306) Escherichia coli APEC O1 4495343 YP_859090.1 CDS rbbA NC_008563.1 3925306 3928041 R fused ribosome-associated ATPase: ATP-binding protein, membrane protein complement(3925306..3928041) Escherichia coli APEC O1 4495344 YP_859091.1 CDS yhiI NC_008563.1 3928038 3929105 R hypothetical protein complement(3928038..3929105) Escherichia coli APEC O1 4495345 YP_859092.1 CDS yhiM NC_008563.1 3929827 3930891 D hypothetical protein 3929827..3930891 Escherichia coli APEC O1 4495115 YP_859093.1 CDS yhiN NC_008563.1 3930978 3932171 R hypothetical protein complement(3930978..3932171) Escherichia coli APEC O1 4495116 YP_859094.1 CDS pitA NC_008563.1 3932403 3933902 D phosphate transporter low-affinity 3932403..3933902 Escherichia coli APEC O1 4495117 YP_859095.1 CDS uspB NC_008563.1 3933973 3934308 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3933973..3934308) Escherichia coli APEC O1 4495118 YP_859096.1 CDS uspA NC_008563.1 3934699 3935133 D universal stress global response regulator UspA 3934699..3935133 Escherichia coli APEC O1 4495119 YP_859097.1 CDS yhiP NC_008563.1 3935450 3936919 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3935450..3936919 Escherichia coli APEC O1 4495120 YP_859098.1 CDS yhiQ NC_008563.1 3936968 3937825 R predicted SAM-dependent methyltransferase; methyltransferase complement(3936968..3937825) Escherichia coli APEC O1 4495121 YP_859099.1 CDS prlC NC_008563.1 3937728 3939770 R oligopeptidase A complement(3937728..3939770) Escherichia coli APEC O1 4495122 YP_859100.1 CDS yhiR NC_008563.1 3939973 3940815 D DNA (exogenous) processing protein 3939973..3940815 Escherichia coli APEC O1 4495123 YP_859101.1 CDS gor NC_008563.1 3940887 3942239 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3940887..3942239 Escherichia coli APEC O1 4495124 YP_859102.1 CDS arsC NC_008563.1 3942910 3943335 D arsenate reductase 3942910..3943335 Escherichia coli APEC O1 4495125 YP_859103.1 CDS slp NC_008563.1 3944486 3945085 D outer membrane protein 3944486..3945085 Escherichia coli APEC O1 4495126 YP_859104.1 CDS yhiF NC_008563.1 3945238 3945768 D DNA-binding ranscriptional regulator 3945238..3945768 Escherichia coli APEC O1 4495127 YP_859105.1 CDS chuS NC_008563.1 3945825 3946853 R heme/hemoglobin transport protein ChuS complement(3945825..3946853) Escherichia coli APEC O1 4495128 YP_859106.1 CDS chuA NC_008563.1 3946902 3948884 R outer membrane heme/hemoglobin receptor ChuA complement(3946902..3948884) Escherichia coli APEC O1 4495129 YP_859107.1 CDS chuT NC_008563.1 3949568 3950482 D periplasmic binding protein ChuT 3949568..3950482 Escherichia coli APEC O1 4495130 YP_859108.1 CDS chuW NC_008563.1 3950502 3951839 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3950502..3951839 Escherichia coli APEC O1 4495131 YP_859109.1 CDS APECO1_2945 NC_008563.1 3951852 3952346 D hypothetical protein 3951852..3952346 Escherichia coli APEC O1 4495132 YP_859110.1 CDS APECO1_2944 NC_008563.1 3952346 3952969 D hypothetical protein 3952346..3952969 Escherichia coli APEC O1 4495133 YP_859111.1 CDS chuU NC_008563.1 3953054 3954010 D permease of iron ABCtransport system 3953054..3954010 Escherichia coli APEC O1 4495134 YP_859112.1 CDS hmuV NC_008563.1 3954007 3954777 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3954007..3954777 Escherichia coli APEC O1 4495484 YP_859113.1 CDS yhiD NC_008563.1 3954829 3955476 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(3954829..3955476) Escherichia coli APEC O1 4495485 YP_859114.1 CDS hdeB NC_008563.1 3955540 3955878 R acid-resistance protein complement(3955540..3955878) Escherichia coli APEC O1 4495486 YP_859115.1 CDS hdeA NC_008563.1 3955982 3956314 R inactive form; acid-resistance protein complement(3955982..3956314) Escherichia coli APEC O1 4495487 YP_859116.1 CDS hdeD NC_008563.1 3956569 3957141 D acid-resistance membrane protein 3956569..3957141 Escherichia coli APEC O1 4495488 YP_859117.1 CDS gadE NC_008563.1 3957907 3958467 D DNA-binding transcriptional activator 3957907..3958467 Escherichia coli APEC O1 4495489 YP_859118.1 CDS APECO1_2936 NC_008563.1 3958511 3958804 D hypothetical protein 3958511..3958804 Escherichia coli APEC O1 4495490 YP_859119.1 CDS mdtE NC_008563.1 3958806 3959963 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3958806..3959963 Escherichia coli APEC O1 4495491 YP_859120.1 CDS mdtF NC_008563.1 3959988 3963101 D multidrug transporter MdtF, RpoS-dependent 3959988..3963101 Escherichia coli APEC O1 4495492 YP_859121.1 CDS yhiW NC_008563.1 3963464 3964192 R DNA-binding transcriptional activator YhiW complement(3963464..3964192) Escherichia coli APEC O1 4495493 YP_859122.1 CDS gadX NC_008563.1 3964560 3965384 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3964560..3965384) Escherichia coli APEC O1 4495494 YP_859123.1 CDS gadB NC_008563.1 3965752 3967182 R glutamate decarboxylase complement(3965752..3967182) Escherichia coli APEC O1 4495495 YP_859124.1 CDS yhjA NC_008563.1 3967363 3968760 R cytochrome C peroxidase complement(3967363..3968760) Escherichia coli APEC O1 4495496 YP_859125.1 CDS treF NC_008563.1 3969165 3970814 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3969165..3970814 Escherichia coli APEC O1 4495497 YP_859126.1 CDS yhjB NC_008563.1 3970865 3971467 R DNA-binding response regulator in two-component regulatory system complement(3970865..3971467) Escherichia coli APEC O1 4495498 YP_859127.1 CDS yhjC NC_008563.1 3971915 3972886 D DNA-binding transcriptional regulator YhjC 3971915..3972886 Escherichia coli APEC O1 4495499 YP_859128.1 CDS yhjD NC_008563.1 3972935 3973948 D hypothetical protein 3972935..3973948 Escherichia coli APEC O1 4495500 YP_859129.1 CDS yhjE NC_008563.1 3974341 3975663 D metabolite transport protein YhjE 3974341..3975663 Escherichia coli APEC O1 4495501 YP_859130.1 CDS yhjG NC_008563.1 3975704 3977779 R outer membrane biogenesis protein YhjG complement(3975704..3977779) Escherichia coli APEC O1 4495502 YP_859131.1 CDS yhjJ NC_008563.1 3977834 3978601 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(3977834..3978601) Escherichia coli APEC O1 4494081 YP_859132.1 CDS kdgK NC_008563.1 3978614 3979762 D 2-dehydro-3-deoxygluconokinase 3978614..3979762 Escherichia coli APEC O1 4494082 YP_859133.1 CDS yhjJ NC_008563.1 3979858 3981354 R zinc-dependent peptidase complement(3979858..3981354) Escherichia coli APEC O1 4494083 YP_859134.1 CDS dctA NC_008563.1 3981574 3982860 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3981574..3982860) Escherichia coli APEC O1 4494084 YP_859135.1 CDS yhjK NC_008563.1 3983043 3984998 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase complement(3983043..3984998) Escherichia coli APEC O1 4494085 YP_859136.1 CDS yhjL NC_008563.1 3985113 3988586 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3985113..3988586) Escherichia coli APEC O1 4494086 YP_859137.1 CDS bcsZ NC_008563.1 3988568 3989674 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3988568..3989674) Escherichia coli APEC O1 4494087 YP_859138.1 CDS bcsB NC_008563.1 3989681 3992020 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3989681..3992020) Escherichia coli APEC O1 4494088 YP_859139.1 CDS bcsA NC_008563.1 3992031 3994697 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3992031..3994697) Escherichia coli APEC O1 4494089 YP_859140.1 CDS yhjQ NC_008563.1 3994646 3995398 R cell division protein complement(3994646..3995398) Escherichia coli APEC O1 4494090 YP_859141.1 CDS yhjS NC_008563.1 3995871 3997442 D hypothetical protein 3995871..3997442 Escherichia coli APEC O1 4494091 YP_859142.1 CDS yhjU NC_008563.1 3997627 3999306 D inner membrane protein; hypothetical protein 3997627..3999306 Escherichia coli APEC O1 4494092 YP_859143.1 CDS APECO1_2912 NC_008563.1 3999571 3999870 D hypothetical protein 3999571..3999870 Escherichia coli APEC O1 4494094 YP_859144.1 CDS APECO1_2911 NC_008563.1 4000045 4000341 D hypothetical protein 4000045..4000341 Escherichia coli APEC O1 4494095 YP_859145.1 CDS APECO1_2910 NC_008563.1 4000357 4000632 R hypothetical protein complement(4000357..4000632) Escherichia coli APEC O1 4494096 YP_859146.1 CDS yhjV NC_008563.1 4000940 4002211 D hypothetical protein 4000940..4002211 Escherichia coli APEC O1 4494097 YP_859147.1 CDS dppF NC_008563.1 4002241 4003245 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(4002241..4003245) Escherichia coli APEC O1 4494098 YP_859148.1 CDS dppD NC_008563.1 4003242 4004225 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(4003242..4004225) Escherichia coli APEC O1 4494099 YP_859149.1 CDS dppC NC_008563.1 4004236 4005138 R dipeptide transporter complement(4004236..4005138) Escherichia coli APEC O1 4494100 YP_859150.1 CDS dppB NC_008563.1 4005148 4006167 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(4005148..4006167) Escherichia coli APEC O1 4492757 YP_859151.1 CDS dppA NC_008563.1 4006318 4007925 R dipeptide transporter protein DppA complement(4006318..4007925) Escherichia coli APEC O1 4492758 YP_859153.1 CDS yhjW NC_008563.1 4008834 4010525 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(4008834..4010525) Escherichia coli APEC O1 4492760 YP_859154.1 CDS yhjX NC_008563.1 4010849 4012057 R permease; transporter complement(4010849..4012057) Escherichia coli APEC O1 4492761 YP_859155.1 CDS yhjY NC_008563.1 4012286 4012984 R hypothetical protein complement(4012286..4012984) Escherichia coli APEC O1 4492762 YP_859156.2 CDS tag NC_008563.1 4013142 4013705 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 4013142..4013705 Escherichia coli APEC O1 4492763 YP_859157.1 CDS yiaC NC_008563.1 4013702 4014142 D hypothetical protein 4013702..4014142 Escherichia coli APEC O1 4492764 YP_859158.1 CDS bisC NC_008563.1 4014111 4016390 R biotin sulfoxide reductase complement(4014111..4016390) Escherichia coli APEC O1 4492765 YP_859159.1 CDS yiaD NC_008563.1 4016597 4017256 D lipoprotein; outer membrane lipoprotein 4016597..4017256 Escherichia coli APEC O1 4492766 YP_859160.1 CDS tkrA NC_008563.1 4017348 4018334 D 2-ketoaldonate reductase/glyoxylate reductase B 4017348..4018334 Escherichia coli APEC O1 4492767 YP_859161.1 CDS yiaF NC_008563.1 4018384 4019214 R hypothetical protein complement(4018384..4019214) Escherichia coli APEC O1 4492768 YP_859162.1 CDS yiaG NC_008563.1 4019528 4019818 D transcriptional regulator 4019528..4019818 Escherichia coli APEC O1 4492769 YP_859163.1 CDS APECO1_2892 NC_008563.1 4020036 4020461 R hypothetical protein complement(4020036..4020461) Escherichia coli APEC O1 4492770 YP_859164.1 CDS glyS NC_008563.1 4020974 4023043 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(4020974..4023043) Escherichia coli APEC O1 4492771 YP_859165.1 CDS glyQ NC_008563.1 4023053 4023964 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(4023053..4023964) Escherichia coli APEC O1 4492772 YP_859166.1 CDS ysaB NC_008563.1 4024059 4024358 R lipoprotein; hypothetical protein complement(4024059..4024358) Escherichia coli APEC O1 4492773 YP_859167.1 CDS yiaH NC_008563.1 4024533 4025528 D hypothetical protein 4024533..4025528 Escherichia coli APEC O1 4492774 YP_859168.1 CDS yiaA NC_008563.1 4025570 4026007 R hypothetical protein complement(4025570..4026007) Escherichia coli APEC O1 4492775 YP_859169.1 CDS yiaB NC_008563.1 4026053 4026406 R inner membrane protein; hypothetical protein complement(4026053..4026406) Escherichia coli APEC O1 4492678 YP_859170.1 CDS xylB NC_008563.1 4026563 4028017 R xylulokinase complement(4026563..4028017) Escherichia coli APEC O1 4492679 YP_859171.2 CDS xylA NC_008563.1 4028089 4029411 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(4028089..4029411) Escherichia coli APEC O1 4492680 YP_859172.1 CDS xylF NC_008563.1 4029777 4030769 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4029777..4030769 Escherichia coli APEC O1 4492681 YP_859173.2 CDS xylG NC_008563.1 4030847 4032388 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4030847..4032388 Escherichia coli APEC O1 4492682 YP_859174.1 CDS xylH NC_008563.1 4032366 4033547 D DNA-binding transcriptional activator, xylose-binding 4032366..4033547 Escherichia coli APEC O1 4492683 YP_859175.1 CDS xylR NC_008563.1 4033625 4034803 D DNA-binding transcriptional activator, xylose-binding 4033625..4034803 Escherichia coli APEC O1 4492684 YP_859176.1 CDS bax NC_008563.1 4034911 4035735 R hypothetical protein complement(4034911..4035735) Escherichia coli APEC O1 4492685 YP_859177.1 CDS malS NC_008563.1 4036055 4038085 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4036055..4038085 Escherichia coli APEC O1 4492686 YP_859178.1 CDS avtA NC_008563.1 4038263 4039516 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4038263..4039516 Escherichia coli APEC O1 4492687 YP_859179.1 CDS ysaA NC_008563.1 4039668 4040147 R electron transport protein YsaA complement(4039668..4040147) Escherichia coli APEC O1 4492688 YP_859180.1 CDS yiaJ NC_008563.1 4040243 4041091 R DNA-binding transcriptional repressor complement(4040243..4041091) Escherichia coli APEC O1 4492689 YP_859181.1 CDS yiaK NC_008563.1 4041292 4042290 D oxidoreductase; NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4041292..4042290 Escherichia coli APEC O1 4492690 YP_859182.1 CDS yiaL NC_008563.1 4042302 4042766 D hypothetical protein 4042302..4042766 Escherichia coli APEC O1 4492691 YP_859183.1 CDS APECO1_2873 NC_008563.1 4042789 4043709 D hypothetical protein 4042789..4043709 Escherichia coli APEC O1 4492692 YP_859184.1 CDS APECO1_2872 NC_008563.1 4044095 4045567 D YiaN-like; DedA family membrane protein 4044095..4045567 Escherichia coli APEC O1 4492693 YP_859185.1 CDS yiaO NC_008563.1 4045585 4046571 D extracellular substrate-binding protein YiaO 4045585..4046571 Escherichia coli APEC O1 4492694 YP_859186.1 CDS lyxK NC_008563.1 4046575 4048071 D L-xylulose kinase 4046575..4048071 Escherichia coli APEC O1 4492695 YP_859187.1 CDS sgbH NC_008563.1 4048068 4048730 D 3-hexulose-6-phosphate synthase; catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4048068..4048730 Escherichia coli APEC O1 4492696 YP_859188.1 CDS sgbU NC_008563.1 4048690 4049583 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4048690..4049583 Escherichia coli APEC O1 4492697 YP_859189.1 CDS APECO1_2867 NC_008563.1 4049580 4050317 R hypothetical protein complement(4049580..4050317) Escherichia coli APEC O1 4491772 YP_859190.1 CDS aldB NC_008563.1 4050319 4051947 R lactaldehyde dehydrogenase complement(4050319..4051947) Escherichia coli APEC O1 4491774 YP_859191.1 CDS APECO1_2865 NC_008563.1 4051965 4053260 R hypothetical protein complement(4051965..4053260) Escherichia coli APEC O1 4491775 YP_859192.1 CDS yiaY NC_008563.1 4053390 4054541 R alcohol dehydrogenase complement(4053390..4054541) Escherichia coli APEC O1 4491776 YP_859193.1 CDS selB NC_008563.1 4054732 4056576 R selenocysteinyl-tRNA-specific translation factor complement(4054732..4056576) Escherichia coli APEC O1 4491777 YP_859194.1 CDS selA NC_008563.1 4056573 4057964 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4056573..4057964) Escherichia coli APEC O1 4491778 YP_859195.1 CDS yibF NC_008563.1 4058062 4058670 R glutathione S-transferase complement(4058062..4058670) Escherichia coli APEC O1 4491779 YP_859196.1 CDS yibH NC_008563.1 4058741 4059877 R hypothetical protein complement(4058741..4059877) Escherichia coli APEC O1 4491780 YP_859197.1 CDS yibI NC_008563.1 4059880 4060242 R inner membrane protein; hypothetical protein complement(4059880..4060242) Escherichia coli APEC O1 4491781 YP_859198.1 CDS mtlA NC_008563.1 4060778 4062691 D PTS system mannitol-specific transporter subunit IIABC 4060778..4062691 Escherichia coli APEC O1 4491782 YP_859199.1 CDS mtlD NC_008563.1 4062830 4064158 D mannitol-1-phosphate 5-dehydrogenase 4062830..4064158 Escherichia coli APEC O1 4491783 YP_859200.1 CDS mtlR NC_008563.1 4064158 4064745 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4064158..4064745 Escherichia coli APEC O1 4491784 YP_859201.1 CDS APECO1_2855 NC_008563.1 4065249 4065611 D hypothetical protein 4065249..4065611 Escherichia coli APEC O1 4491785 YP_859202.1 CDS APECO1_2854 NC_008563.1 4066404 4066853 D hypothetical protein 4066404..4066853 Escherichia coli APEC O1 4491786 YP_859203.1 CDS yadA NC_008563.1 4066897 4071648 D autotransporter/adhesin 4066897..4071648 Escherichia coli APEC O1 4491787 YP_859204.1 CDS lldP NC_008563.1 4072058 4073713 D L-lactate permease 4072058..4073713 Escherichia coli APEC O1 4491788 YP_859205.1 CDS lldR NC_008563.1 4073713 4074489 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4073713..4074489 Escherichia coli APEC O1 4491789 YP_859206.1 CDS lldD NC_008563.1 4074486 4075676 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4074486..4075676 Escherichia coli APEC O1 4491790 YP_859207.1 CDS yibK NC_008563.1 4075724 4076197 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4075724..4076197 Escherichia coli APEC O1 4493516 YP_859208.1 CDS cysE NC_008563.1 4076252 4077073 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4076252..4077073) Escherichia coli APEC O1 4493517 YP_859209.1 CDS gpsA NC_008563.1 4077153 4078172 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4077153..4078172) Escherichia coli APEC O1 4493518 YP_859210.1 CDS secB NC_008563.1 4078172 4078699 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4078172..4078699) Escherichia coli APEC O1 4493519 YP_859211.1 CDS APECO1_2845 NC_008563.1 4078769 4079038 D hypothetical protein 4078769..4079038 Escherichia coli APEC O1 4493520 YP_859212.1 CDS yibN NC_008563.1 4079095 4079526 R rhodanese-related sulfurtransferase complement(4079095..4079526) Escherichia coli APEC O1 4493521 YP_859213.1 CDS yibO NC_008563.1 4079771 4081315 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4079771..4081315 Escherichia coli APEC O1 4493522 YP_859214.1 CDS envC NC_008563.1 4081325 4082608 D hypothetical protein 4081325..4082608 Escherichia coli APEC O1 4493523 YP_859215.1 CDS yibQ NC_008563.1 4082738 4083571 D polysaccharide deacetylase 4082738..4083571 Escherichia coli APEC O1 4493524 YP_859216.1 CDS yibD NC_008563.1 4083558 4084592 R glycosyl transferase family protein complement(4083558..4084592) Escherichia coli APEC O1 4493525 YP_859217.1 CDS tdh NC_008563.1 4084831 4085856 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4084831..4085856) Escherichia coli APEC O1 4493526 YP_859218.1 CDS kbl NC_008563.1 4085866 4087062 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(4085866..4087062) Escherichia coli APEC O1 4492582 YP_859219.1 CDS rfaD NC_008563.1 4087276 4088208 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4087276..4088208 Escherichia coli APEC O1 4492583 YP_859220.1 CDS rfaF NC_008563.1 4088218 4089264 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4088218..4089264 Escherichia coli APEC O1 4492584 YP_859221.1 CDS rfaC NC_008563.1 4089268 4090248 D ADP-heptose--LPS heptosyltransferase 4089268..4090248 Escherichia coli APEC O1 4492585 YP_859222.1 CDS waaL NC_008563.1 4090318 4091571 R lipid A-core, surface polymer ligase complement(4090318..4091571) Escherichia coli APEC O1 4492586 YP_859223.1 CDS waaV NC_008563.1 4091617 4092600 R beta-1,3-glucosyltransferase complement(4091617..4092600) Escherichia coli APEC O1 4492587 YP_859224.1 CDS rfaJ NC_008563.1 4092682 4093710 R UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase complement(4092682..4093710) Escherichia coli APEC O1 4492588 YP_859225.1 CDS APECO1_2831 NC_008563.1 4093736 4094428 R lipopolysaccharide core biosynthesis protein complement(4093736..4094428) Escherichia coli APEC O1 4492589 YP_859226.1 CDS rfaJ NC_008563.1 4094438 4095433 R lipopolysaccharide 1,2-glucosyltransferase complement(4094438..4095433) Escherichia coli APEC O1 4492590 YP_859227.1 CDS rafI NC_008563.1 4095450 4096466 R lipopolysaccharide 1,3-galactosyltransferase complement(4095450..4096466) Escherichia coli APEC O1 4492591 YP_859228.1 CDS rfaP NC_008563.1 4096482 4097288 R lipopolysaccharide core biosynthesis protein RfaP complement(4096482..4097288) Escherichia coli APEC O1 4492592 YP_859229.1 CDS rfaG NC_008563.1 4097272 4098396 R lipopolysaccharide core biosynthesis glucosyltransferase I complement(4097272..4098396) Escherichia coli APEC O1 4492593 YP_859230.1 CDS rfaQ NC_008563.1 4098393 4099451 R lipopolysaccharide core biosynthesis protein complement(4098393..4099451) Escherichia coli APEC O1 4492594 YP_859231.1 CDS kdtA NC_008563.1 4099864 4101141 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4099864..4101141 Escherichia coli APEC O1 4492595 YP_859232.1 CDS mutM NC_008563.1 4101667 4102476 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4101667..4102476) Escherichia coli APEC O1 4492596 YP_859233.1 CDS radC NC_008563.1 4103215 4103889 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4103215..4103889) Escherichia coli APEC O1 4492597 YP_859234.2 CDS dfp NC_008563.1 4104055 4105275 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4104055..4105275 Escherichia coli APEC O1 4492598 YP_859235.1 CDS dut NC_008563.1 4105253 4105711 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4105253..4105711 Escherichia coli APEC O1 4492599 YP_859236.1 CDS slmA NC_008563.1 4105776 4106414 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4105776..4106414 Escherichia coli APEC O1 4492600 YP_859237.1 CDS pyrE NC_008563.1 4106451 4107107 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4106451..4107107) Escherichia coli APEC O1 4495269 YP_859238.1 CDS rph NC_008563.1 4107158 4107874 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4107158..4107874) Escherichia coli APEC O1 4495270 YP_859239.1 CDS yicC NC_008563.1 4108001 4108864 D alpha-helix protein; hypothetical protein 4108001..4108864 Escherichia coli APEC O1 4495271 YP_859240.1 CDS dinD NC_008563.1 4109074 4109910 D DNA-damage-inducible protein D 4109074..4109910 Escherichia coli APEC O1 4495272 YP_859241.1 CDS APECO1_2815 NC_008563.1 4110148 4110819 D hypothetical protein 4110148..4110819 Escherichia coli APEC O1 4495273 YP_859242.1 CDS ligB NC_008563.1 4110816 4112504 R LigB; this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4110816..4112504) Escherichia coli APEC O1 4495274 YP_859243.1 CDS gmk NC_008563.1 4112699 4113379 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4112699..4113379 Escherichia coli APEC O1 4495275 YP_859244.1 CDS rpoZ NC_008563.1 4113434 4113709 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4113434..4113709 Escherichia coli APEC O1 4495276 YP_859245.1 CDS spoT NC_008563.1 4113875 4115836 D bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4113875..4115836 Escherichia coli APEC O1 4495277 YP_859246.1 CDS spoU NC_008563.1 4115843 4116532 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4115843..4116532 Escherichia coli APEC O1 4495278 YP_859247.1 CDS recG NC_008563.1 4116505 4118619 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4116505..4118619 Escherichia coli APEC O1 4495279 YP_859248.1 CDS APECO1_2808 NC_008563.1 4118653 4119858 R glutamate transport protein complement(4118653..4119858) Escherichia coli APEC O1 4495280 YP_859249.1 CDS yicE NC_008563.1 4120138 4121529 D purine permease YicE 4120138..4121529 Escherichia coli APEC O1 4495281 YP_859250.1 CDS yicH NC_008563.1 4121626 4123359 D hypothetical protein 4121626..4123359 Escherichia coli APEC O1 4495282 YP_859251.1 CDS APECO1_2805 NC_008563.1 4123403 4124122 R hypothetical protein complement(4123403..4124122) Escherichia coli APEC O1 4495283 YP_859252.1 CDS yajF NC_008563.1 4124064 4125029 R hypothetical protein complement(4124064..4125029) Escherichia coli APEC O1 4495284 YP_859253.1 CDS APECO1_2803 NC_008563.1 4125044 4125904 R hypothetical protein complement(4125044..4125904) Escherichia coli APEC O1 4495285 YP_859254.1 CDS APECO1_2802 NC_008563.1 4125985 4126836 R aldolase complement(4125985..4126836) Escherichia coli APEC O1 4495286 YP_859255.1 CDS APECO1_2801 NC_008563.1 4126848 4127939 R PTS enzyme-II fructose complement(4126848..4127939) Escherichia coli APEC O1 4495287 YP_859256.1 CDS APECO1_2800 NC_008563.1 4127964 4128278 R PTS system, fructose-like-2 IIB component 1 complement(4127964..4128278) Escherichia coli APEC O1 4495288 YP_859257.1 CDS APECO1_2799 NC_008563.1 4128296 4128766 R phosphotransferase system (PTS), fructose-specific complement(4128296..4128766) Escherichia coli APEC O1 4495769 YP_859258.1 CDS APECO1_2798 NC_008563.1 4128793 4130346 R transcriptional antiterminator complement(4128793..4130346) Escherichia coli APEC O1 4495770 YP_859259.1 CDS yicI NC_008563.1 4130641 4132959 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(4130641..4132959) Escherichia coli APEC O1 4495771 YP_859260.1 CDS yicJ NC_008563.1 4132969 4134408 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4132969..4134408) Escherichia coli APEC O1 4495772 YP_859261.1 CDS APECO1_2795 NC_008563.1 4134662 4135828 D virulence protein RhuM; hypothetical protein 4134662..4135828 Escherichia coli APEC O1 4495773 YP_859262.1 CDS APECO1_2794 NC_008563.1 4136398 4136766 D hypothetical protein 4136398..4136766 Escherichia coli APEC O1 4495774 YP_859263.1 CDS yicL NC_008563.1 4137009 4137986 D hypothetical protein 4137009..4137986 Escherichia coli APEC O1 4495775 YP_859264.1 CDS nlpA NC_008563.1 4137990 4138808 R hypothetical protein complement(4137990..4138808) Escherichia coli APEC O1 4495776 YP_859265.1 CDS yicS NC_008563.1 4138961 4139323 D hypothetical protein 4138961..4139323 Escherichia coli APEC O1 4495777 YP_859266.2 CDS nepI NC_008563.1 4139364 4140554 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4139364..4140554) Escherichia coli APEC O1 4495778 YP_859267.1 CDS yicN NC_008563.1 4140765 4141244 R 2-methylthioadenine synthetase; hypothetical protein complement(4140765..4141244) Escherichia coli APEC O1 4495779 YP_859268.1 CDS yicO NC_008563.1 4141270 4142682 R xanthine/uracil permase YicO complement(4141270..4142682) Escherichia coli APEC O1 4495780 YP_859269.1 CDS ade NC_008563.1 4142779 4144545 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4142779..4144545 Escherichia coli APEC O1 4495781 YP_859270.1 CDS uhpT NC_008563.1 4144592 4145983 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4144592..4145983) Escherichia coli APEC O1 4495782 YP_859271.1 CDS uhpC NC_008563.1 4146121 4147443 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4146121..4147443) Escherichia coli APEC O1 4495783 YP_859272.1 CDS uhpB NC_008563.1 4147450 4148952 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4147450..4148952) Escherichia coli APEC O1 4495784 YP_859273.1 CDS uhpA NC_008563.1 4148952 4149542 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4148952..4149542) Escherichia coli APEC O1 4495785 YP_859274.1 CDS ilvN NC_008563.1 4149615 4149905 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4149615..4149905) Escherichia coli APEC O1 4495786 YP_859275.1 CDS ilvB NC_008563.1 4149909 4151597 R acetolactate synthase catalytic subunit complement(4149909..4151597) Escherichia coli APEC O1 4495787 YP_859276.1 CDS APECO1_2780 NC_008563.1 4151581 4151913 D hypothetical protein 4151581..4151913 Escherichia coli APEC O1 4494776 YP_859277.1 CDS emrD NC_008563.1 4152196 4153386 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4152196..4153386 Escherichia coli APEC O1 4494777 YP_859278.1 CDS yidF NC_008563.1 4153394 4153891 R hypothetical protein complement(4153394..4153891) Escherichia coli APEC O1 4494778 YP_859279.1 CDS yidG NC_008563.1 4153888 4154250 R hypothetical protein complement(4153888..4154250) Escherichia coli APEC O1 4494779 YP_859280.1 CDS yidH NC_008563.1 4154240 4154647 R hypothetical protein complement(4154240..4154647) Escherichia coli APEC O1 4494780 YP_859281.1 CDS yidJ NC_008563.1 4154647 4156140 R sulfatase/phosphatase YidJ complement(4154647..4156140) Escherichia coli APEC O1 4494781 YP_859282.1 CDS yidK NC_008563.1 4156137 4157852 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4156137..4157852) Escherichia coli APEC O1 4494782 YP_859283.1 CDS yidL NC_008563.1 4157989 4158885 D DNA-binding transcriptional regulator YidL 4157989..4158885 Escherichia coli APEC O1 4494783 YP_859284.1 CDS yidE NC_008563.1 4158975 4160660 R hypothetical protein complement(4158975..4160660) Escherichia coli APEC O1 4494784 YP_859285.2 CDS ibpB NC_008563.1 4160833 4161261 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4160833..4161261) Escherichia coli APEC O1 4494785 YP_859286.1 CDS ibpA NC_008563.1 4161373 4161786 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4161373..4161786) Escherichia coli APEC O1 4494786 YP_859287.1 CDS yidQ NC_008563.1 4162017 4162424 D hypothetical protein 4162017..4162424 Escherichia coli APEC O1 4494787 YP_859288.1 CDS yidR NC_008563.1 4162428 4163675 R hypothetical protein complement(4162428..4163675) Escherichia coli APEC O1 4494788 YP_859289.1 CDS yidS NC_008563.1 4163722 4164843 D dehydrogenase; FAD/NAD(P)-binding domain; oxidoreductase 4163722..4164843 Escherichia coli APEC O1 4494789 YP_859290.1 CDS dgoT NC_008563.1 4164804 4166141 R D-galactonate transporter complement(4164804..4166141) Escherichia coli APEC O1 4494790 YP_859291.1 CDS dgoD NC_008563.1 4166216 4167364 R galactonate dehydratase complement(4166216..4167364) Escherichia coli APEC O1 4494791 YP_859292.1 CDS dgoA NC_008563.1 4167361 4167978 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4167361..4167978) Escherichia coli APEC O1 4494792 YP_859293.1 CDS dgoK NC_008563.1 4167962 4168840 R 2-oxo-3-deoxygalactonate kinase DgoK complement(4167962..4168840) Escherichia coli APEC O1 4494793 YP_859294.1 CDS dgoR NC_008563.1 4168837 4169526 R galactonate operon transcriptional repressor DgoR complement(4168837..4169526) Escherichia coli APEC O1 4494794 YP_859295.1 CDS APECO1_2761 NC_008563.1 4169805 4170461 D hypothetical protein 4169805..4170461 Escherichia coli APEC O1 4494795 YP_859296.1 CDS yidA NC_008563.1 4170505 4171317 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4170505..4171317) Escherichia coli APEC O1 4492310 YP_859297.1 CDS yidB NC_008563.1 4171432 4171839 R hypothetical protein complement(4171432..4171839) Escherichia coli APEC O1 4492311 YP_859298.1 CDS gyrB NC_008563.1 4172070 4174484 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4172070..4174484) Escherichia coli APEC O1 4492312 YP_859299.1 CDS recF NC_008563.1 4174513 4175586 R RecF, a recombinational DNA repair ATPase; Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4174513..4175586) Escherichia coli APEC O1 4492313 YP_859300.1 CDS dnaN NC_008563.1 4175586 4176686 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4175586..4176686) Escherichia coli APEC O1 4492314 YP_859301.1 CDS dnaA NC_008563.1 4176691 4178106 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4176691..4178106) Escherichia coli APEC O1 4492315 YP_859302.1 CDS rnpA NC_008563.1 4178858 4179217 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4178858..4179217 Escherichia coli APEC O1 4492316 YP_859303.1 CDS yidC NC_008563.1 4179441 4181087 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; hypothetical protein 4179441..4181087 Escherichia coli APEC O1 4492317 YP_859304.1 CDS trmE NC_008563.1 4181193 4182557 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4181193..4182557 Escherichia coli APEC O1 4492318 YP_859305.1 CDS tnaA NC_008563.1 4183079 4184509 D tryptophan deaminase, PLP-dependent; tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4183079..4184509 Escherichia coli APEC O1 4492319 YP_859306.1 CDS tnaB NC_008563.1 4184601 4185848 D tryptophan transporter of low affinity; tryptophan permease TnaB 4184601..4185848 Escherichia coli APEC O1 4492320 YP_859307.1 CDS mdtL NC_008563.1 4185980 4187155 D drug/chloramphenicol transport protein (MFS family); Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4185980..4187155 Escherichia coli APEC O1 4492322 YP_859308.1 CDS yidZ NC_008563.1 4187130 4188089 D predicted DNA-binding transcriptional regulator; Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4187130..4188089 Escherichia coli APEC O1 4492323 YP_859309.1 CDS yieE NC_008563.1 4188234 4188995 D predicted phosphopantetheinyl transferase; hypothetical protein 4188234..4188995 Escherichia coli APEC O1 4492324 YP_859310.1 CDS yieF NC_008563.1 4189017 4189583 D hypothetical protein 4189017..4189583 Escherichia coli APEC O1 4492325 YP_859311.1 CDS yieG NC_008563.1 4189636 4190973 R membrane/transport protein complement(4189636..4190973) Escherichia coli APEC O1 4492326 YP_859312.1 CDS yieH NC_008563.1 4191140 4191805 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4191140..4191805 Escherichia coli APEC O1 4492327 YP_859313.1 CDS yieI NC_008563.1 4191872 4192345 D might be involved in hypersensitivity to nitrofurzone; hypothetical protein 4191872..4192345 Escherichia coli APEC O1 4492328 YP_859314.1 CDS yieK NC_008563.1 4192427 4193149 R isomerase-like; 6-phosphogluconolactonase complement(4192427..4193149) Escherichia coli APEC O1 4495711 YP_859315.1 CDS yieL NC_008563.1 4193164 4194360 R xylanase complement(4193164..4194360) Escherichia coli APEC O1 4495712 YP_859316.1 CDS bglH NC_008563.1 4194360 4195976 R carbohydrate-specific outer membrane porin, cryptic complement(4194360..4195976) Escherichia coli APEC O1 4495713 YP_859317.1 CDS bglB NC_008563.1 4196062 4197456 R 6-phospho-beta-glucosidase complement(4196062..4197456) Escherichia coli APEC O1 4495714 YP_859318.1 CDS bglF NC_008563.1 4197475 4199349 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC complement(4197475..4199349) Escherichia coli APEC O1 4495715 YP_859319.1 CDS bglG NC_008563.1 4199483 4200319 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4199483..4200319) Escherichia coli APEC O1 4495716 YP_859320.1 CDS phoU NC_008563.1 4200605 4201330 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4200605..4201330) Escherichia coli APEC O1 4495717 YP_859321.1 CDS pstB NC_008563.1 4201345 4202118 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4201345..4202118) Escherichia coli APEC O1 4495718 YP_859322.1 CDS pstA NC_008563.1 4202209 4203099 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4202209..4203099) Escherichia coli APEC O1 4495719 YP_859323.1 CDS pstC NC_008563.1 4203099 4204058 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4203099..4204058) Escherichia coli APEC O1 4495720 YP_859324.1 CDS pstS NC_008563.1 4204145 4205185 R periplasmic-binding component of ABC superfamily; phosphate ABC transporter substrate-binding protein complement(4204145..4205185) Escherichia coli APEC O1 4495721 YP_859325.1 CDS glmS NC_008563.1 4205504 4207333 R GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4205504..4207333) Escherichia coli APEC O1 4495722 YP_859326.1 CDS glmU NC_008563.1 4207494 4208864 R GlmU; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4207494..4208864) Escherichia coli APEC O1 4495723 YP_859327.1 CDS APECO1_2730 NC_008563.1 4209110 4209661 D hypothetical protein 4209110..4209661 Escherichia coli APEC O1 4495724 YP_859328.1 CDS atpD NC_008563.1 4209658 4211040 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(4209658..4211040) Escherichia coli APEC O1 4495725 YP_859329.1 CDS atpG NC_008563.1 4211067 4211930 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(4211067..4211930) Escherichia coli APEC O1 4495726 YP_859330.1 CDS APECO1_2727 NC_008563.1 4212086 4213669 D hypothetical protein 4212086..4213669 Escherichia coli APEC O1 4495727 YP_859331.1 CDS APECO1_2726 NC_008563.1 4213775 4214446 D hypothetical protein 4213775..4214446 Escherichia coli APEC O1 4495728 YP_859332.1 CDS atpB NC_008563.1 4214901 4215716 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(4214901..4215716) Escherichia coli APEC O1 4495729 YP_859333.1 CDS atpI NC_008563.1 4215725 4216117 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4215725..4216117) Escherichia coli APEC O1 4495730 YP_859334.1 CDS gidB NC_008563.1 4216722 4217345 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4216722..4217345) Escherichia coli APEC O1 4491978 YP_859335.1 CDS gidA NC_008563.1 4217409 4219298 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4217409..4219298) Escherichia coli APEC O1 4491979 YP_859336.1 CDS mioC NC_008563.1 4219677 4220120 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4219677..4220120) Escherichia coli APEC O1 4491980 YP_859337.1 CDS asnC NC_008563.1 4220210 4220668 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; AsnC family transcriptional regulator complement(4220210..4220668) Escherichia coli APEC O1 4491981 YP_859338.1 CDS asnA NC_008563.1 4220820 4221812 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4220820..4221812 Escherichia coli APEC O1 4491982 YP_859339.1 CDS yieM NC_008563.1 4221817 4223268 R predicted von Willibrand factor-containing protein; contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4221817..4223268) Escherichia coli APEC O1 4491983 YP_859340.1 CDS yieN NC_008563.1 4223262 4224758 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4223262..4224758) Escherichia coli APEC O1 4491984 YP_859341.1 CDS trkD NC_008563.1 4224981 4226849 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4224981..4226849 Escherichia coli APEC O1 4491985 YP_859342.2 CDS rbsD NC_008563.1 4227016 4227435 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4227016..4227435 Escherichia coli APEC O1 4491986 YP_859343.1 CDS rbsA NC_008563.1 4227443 4228948 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4227443..4228948 Escherichia coli APEC O1 4491987 YP_859344.1 CDS rbsC NC_008563.1 4228953 4229918 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4228953..4229918 Escherichia coli APEC O1 4491988 YP_859345.1 CDS rbsB NC_008563.1 4229943 4230833 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4229943..4230833 Escherichia coli APEC O1 4491989 YP_859346.1 CDS rbsK NC_008563.1 4230932 4231888 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4230932..4231888 Escherichia coli APEC O1 4491990 YP_859347.1 CDS rbsR NC_008563.1 4231901 4232884 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4231901..4232884 Escherichia coli APEC O1 4491991 YP_859348.1 CDS yieO NC_008563.1 4232850 4234277 R transporter complement(4232850..4234277) Escherichia coli APEC O1 4491992 YP_859349.1 CDS yieP NC_008563.1 4234300 4234992 R transcriptional regulator complement(4234300..4234992) Escherichia coli APEC O1 4491993 YP_859351.1 CDS hdfR NC_008563.1 4240793 4241632 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4240793..4241632) Escherichia coli APEC O1 4491995 YP_859352.1 CDS APECO1_2705 NC_008563.1 4241751 4242089 D hypothetical protein 4241751..4242089 Escherichia coli APEC O1 4491996 YP_859353.1 CDS yifB NC_008563.1 4242114 4243664 R among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease complement(4242114..4243664) Escherichia coli APEC O1 4492990 YP_859354.1 CDS ilvG NC_008563.1 4244225 4245871 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4244225..4245871 Escherichia coli APEC O1 4492991 YP_859355.1 CDS ilvM NC_008563.1 4245868 4246131 D acetolactate synthase 2 regulatory subunit 4245868..4246131 Escherichia coli APEC O1 4492992 YP_859356.1 CDS ilvE NC_008563.1 4246151 4247080 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4246151..4247080 Escherichia coli APEC O1 4492993 YP_859357.1 CDS ilvD NC_008563.1 4247145 4248995 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4247145..4248995 Escherichia coli APEC O1 4492994 YP_859358.1 CDS ilvA NC_008563.1 4248995 4250542 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4248995..4250542 Escherichia coli APEC O1 4492995 YP_859359.1 CDS ilvY NC_008563.1 4250539 4251513 R DNA-binding transcriptional dual regulator; participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4250539..4251513) Escherichia coli APEC O1 4492996 YP_859360.1 CDS ilvC NC_008563.1 4251579 4253054 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4251579..4253054 Escherichia coli APEC O1 4492997 YP_859361.1 CDS ppiC NC_008563.1 4253100 4253381 R peptidyl-prolyl cis-trans isomerase C complement(4253100..4253381) Escherichia coli APEC O1 4492998 YP_859362.1 CDS rep NC_008563.1 4253468 4255489 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4253468..4255489 Escherichia coli APEC O1 4492999 YP_859363.1 CDS gppA NC_008563.1 4255536 4257029 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4255536..4257029) Escherichia coli APEC O1 4493000 YP_859364.1 CDS rhlB NC_008563.1 4257156 4258421 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4257156..4258421) Escherichia coli APEC O1 4493001 YP_859365.1 CDS APECO1_2692 NC_008563.1 4258546 4258938 R hypothetical protein complement(4258546..4258938) Escherichia coli APEC O1 4493002 YP_859366.1 CDS rho NC_008563.1 4259136 4260467 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4259136..4260467 Escherichia coli APEC O1 4493003 YP_859367.1 CDS rfe NC_008563.1 4260707 4261810 D UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase 4260707..4261810 Escherichia coli APEC O1 4493004 YP_859368.1 CDS wzzE NC_008563.1 4261822 4262868 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4261822..4262868 Escherichia coli APEC O1 4493005 YP_859369.1 CDS rffE NC_008563.1 4262882 4264054 D UDP-N-acetylglucosamine 2-epimerase 4262882..4264054 Escherichia coli APEC O1 4493006 YP_859370.1 CDS wecC NC_008563.1 4264051 4265313 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4264051..4265313 Escherichia coli APEC O1 4493007 YP_859371.1 CDS rffG NC_008563.1 4265313 4266380 D dTDP-glucose 4,6-dehydratase 4265313..4266380 Escherichia coli APEC O1 4493008 YP_859372.1 CDS rffH NC_008563.1 4266399 4267280 D glucose-1-phosphate thymidylyltransferase; lipopolysaccharide biosynthesis protein RffH 4266399..4267280 Escherichia coli APEC O1 4493009 YP_859373.1 CDS rffC NC_008563.1 4267258 4267932 D TDP-fucosamine acetyltransferase 4267258..4267932 Escherichia coli APEC O1 4495445 YP_859374.1 CDS rffA NC_008563.1 4267937 4269067 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4267937..4269067 Escherichia coli APEC O1 4495446 YP_859375.1 CDS wzxE NC_008563.1 4269069 4270319 D O-antigen translocase 4269069..4270319 Escherichia coli APEC O1 4495447 YP_859376.1 CDS rffT NC_008563.1 4270316 4271395 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4270316..4271395 Escherichia coli APEC O1 4495448 YP_859377.1 CDS wecF NC_008563.1 4271392 4272744 D enterobacterial common antigen polymerase; common antigen polymerase 4271392..4272744 Escherichia coli APEC O1 4495449 YP_859378.1 CDS wecG NC_008563.1 4272747 4273487 D UDP-N-acetyl-D-mannosaminuronic acid transferase 4272747..4273487 Escherichia coli APEC O1 4495450 YP_859379.1 CDS yifK NC_008563.1 4273678 4275063 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4273678..4275063 Escherichia coli APEC O1 4495451 YP_859380.1 CDS aslB NC_008563.1 4275749 4276984 D regulator of arylsulfatase activity 4275749..4276984 Escherichia coli APEC O1 4495452 YP_859381.1 CDS aslA NC_008563.1 4277142 4278797 R arylsulfatase-like enzyme complement(4277142..4278797) Escherichia coli APEC O1 4495453 YP_859382.1 CDS hemY NC_008563.1 4279476 4280672 R protoheme IX biogenesis protein complement(4279476..4280672) Escherichia coli APEC O1 4495454 YP_859383.1 CDS hemX NC_008563.1 4280675 4281868 R uroporphyrinogen III C-methyltransferase complement(4280675..4281868) Escherichia coli APEC O1 4495455 YP_859384.1 CDS hemD NC_008563.1 4281890 4282630 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4281890..4282630) Escherichia coli APEC O1 4495456 YP_859385.1 CDS hemC NC_008563.1 4282627 4283589 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4282627..4283589) Escherichia coli APEC O1 4495457 YP_859386.2 CDS cyaA NC_008563.1 4283955 4286501 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4283955..4286501 Escherichia coli APEC O1 4495458 YP_859387.1 CDS cyaY NC_008563.1 4286541 4286861 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4286541..4286861) Escherichia coli APEC O1 4495459 YP_859388.1 CDS APECO1_2670 NC_008563.1 4286909 4288225 R hypothetical protein complement(4286909..4288225) Escherichia coli APEC O1 4495460 YP_859389.1 CDS APECO1_2669 NC_008563.1 4288222 4288791 R hypothetical protein complement(4288222..4288791) Escherichia coli APEC O1 4495461 YP_859390.1 CDS APECO1_2668 NC_008563.1 4288876 4289721 R hypothetical protein complement(4288876..4289721) Escherichia coli APEC O1 4495462 YP_859391.1 CDS dapF NC_008563.1 4290117 4290944 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4290117..4290944 Escherichia coli APEC O1 4495463 YP_859392.1 CDS yigA NC_008563.1 4290941 4291648 D hypothetical protein 4290941..4291648 Escherichia coli APEC O1 4492066 YP_859393.1 CDS xerC NC_008563.1 4291645 4292541 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4291645..4292541 Escherichia coli APEC O1 4492067 YP_859394.1 CDS yigB NC_008563.1 4292541 4293257 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4292541..4293257 Escherichia coli APEC O1 4492068 YP_859395.1 CDS uvrD NC_008563.1 4293341 4295503 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4293341..4295503 Escherichia coli APEC O1 4492069 YP_859396.1 CDS APECO1_2662 NC_008563.1 4295548 4296450 R hypothetical protein complement(4295548..4296450) Escherichia coli APEC O1 4492070 YP_859397.1 CDS yigE NC_008563.1 4296533 4297297 R hypothetical protein complement(4296533..4297297) Escherichia coli APEC O1 4492071 YP_859398.1 CDS corA NC_008563.1 4297667 4298617 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4297667..4298617 Escherichia coli APEC O1 4492072 YP_859399.1 CDS APECO1_2659 NC_008563.1 4298653 4299150 R hypothetical protein complement(4298653..4299150) Escherichia coli APEC O1 4492073 YP_859400.1 CDS APECO1_2658 NC_008563.1 4299147 4299995 R hypothetical protein complement(4299147..4299995) Escherichia coli APEC O1 4492074 YP_859401.1 CDS rarD NC_008563.1 4300306 4301196 R chloramphenical resistance permease complement(4300306..4301196) Escherichia coli APEC O1 4492075 YP_859402.1 CDS yigI NC_008563.1 4301248 4301733 R hypothetical protein complement(4301248..4301733) Escherichia coli APEC O1 4492076 YP_859403.1 CDS pldA NC_008563.1 4301880 4302749 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4301880..4302749 Escherichia coli APEC O1 4492077 YP_859404.1 CDS recQ NC_008563.1 4302868 4304703 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4302868..4304703 Escherichia coli APEC O1 4492078 YP_859405.1 CDS rhtC NC_008563.1 4304767 4305387 D threonine efflux system 4304767..4305387 Escherichia coli APEC O1 4492079 YP_859406.1 CDS rhtB NC_008563.1 4305448 4306068 R homoserine/homoserine lactone efflux protein complement(4305448..4306068) Escherichia coli APEC O1 4492080 YP_859407.1 CDS pldB NC_008563.1 4306179 4307201 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4306179..4307201 Escherichia coli APEC O1 4492081 YP_859408.1 CDS APECO1_2650 NC_008563.1 4307092 4308009 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4307092..4308009 Escherichia coli APEC O1 4492082 YP_859409.1 CDS yigM NC_008563.1 4308085 4308984 D hypothetical protein 4308085..4308984 Escherichia coli APEC O1 4492083 YP_859410.1 CDS metR NC_008563.1 4308872 4309825 R regulator for metE and metH; DNA-binding transcriptional activator, homocysteine-binding complement(4308872..4309825) Escherichia coli APEC O1 4492084 YP_859411.1 CDS metE NC_008563.1 4309943 4312204 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4309943..4312204 Escherichia coli APEC O1 4492085 YP_859412.1 CDS APECO1_2646 NC_008563.1 4312693 4312950 R hypothetical protein complement(4312693..4312950) Escherichia coli APEC O1 4492913 YP_859413.1 CDS APECO1_2645 NC_008563.1 4312947 4313438 R hypothetical protein complement(4312947..4313438) Escherichia coli APEC O1 4492914 YP_859414.1 CDS APECO1_2644 NC_008563.1 4313787 4314080 R hypothetical protein complement(4313787..4314080) Escherichia coli APEC O1 4492915 YP_859415.1 CDS APECO1_2643 NC_008563.1 4314532 4315122 D sugar isomerase 4314532..4315122 Escherichia coli APEC O1 4492916 YP_859416.1 CDS APECO1_2642 NC_008563.1 4315164 4316672 D PTS system, glucose-specific IIBC component 4315164..4316672 Escherichia coli APEC O1 4492917 YP_859417.1 CDS APECO1_2641 NC_008563.1 4316723 4318720 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4316723..4318720 Escherichia coli APEC O1 4492918 YP_859418.1 CDS APECO1_2640 NC_008563.1 4318750 4319595 R transcriptional regulatory protein complement(4318750..4319595) Escherichia coli APEC O1 4492919 YP_859419.1 CDS APECO1_2639 NC_008563.1 4319796 4320701 R transcriptional regulatory protein complement(4319796..4320701) Escherichia coli APEC O1 4492920 YP_859420.1 CDS APECO1_2638 NC_008563.1 4320779 4322002 R cytosine/purines uracil thiamine allantoin permease complement(4320779..4322002) Escherichia coli APEC O1 4492921 YP_859421.1 CDS APECO1_2637 NC_008563.1 4322028 4322417 R hypothetical protein complement(4322028..4322417) Escherichia coli APEC O1 4492922 YP_859422.2 CDS APECO1_2636 NC_008563.1 4322434 4323390 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4322434..4323390) Escherichia coli APEC O1 4492923 YP_859423.1 CDS yahG NC_008563.1 4323383 4324858 R hypothetical protein complement(4323383..4324858) Escherichia coli APEC O1 4492924 YP_859424.1 CDS yahF NC_008563.1 4324804 4326363 R hypothetical protein complement(4324804..4326363) Escherichia coli APEC O1 4492925 YP_859425.1 CDS yahE NC_008563.1 4326458 4327318 R hypothetical protein complement(4326458..4327318) Escherichia coli APEC O1 4492926 YP_859426.1 CDS APECO1_2632 NC_008563.1 4327324 4327992 R isochorismatase hydrolase complement(4327324..4327992) Escherichia coli APEC O1 4492927 YP_859427.1 CDS APECO1_2631 NC_008563.1 4328249 4329124 R dienelactone hydrolase complement(4328249..4329124) Escherichia coli APEC O1 4492928 YP_859428.1 CDS udp NC_008563.1 4329320 4330084 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4329320..4330084 Escherichia coli APEC O1 4492929 YP_859429.1 CDS APECO1_2629 NC_008563.1 4330119 4331609 R hypothetical protein complement(4330119..4331609) Escherichia coli APEC O1 4492930 YP_859430.1 CDS APECO1_2628 NC_008563.1 4331622 4332128 R hypothetical protein complement(4331622..4332128) Escherichia coli APEC O1 4492931 YP_859431.1 CDS APECO1_2627 NC_008563.1 4332145 4333119 R hypothetical protein complement(4332145..4333119) Escherichia coli APEC O1 4494160 YP_859432.1 CDS APECO1_2626 NC_008563.1 4333280 4333804 D aldolase 4333280..4333804 Escherichia coli APEC O1 4494161 YP_859433.1 CDS APECO1_2625 NC_008563.1 4333763 4334767 R 2-keto-3-deoxygalactokinase complement(4333763..4334767) Escherichia coli APEC O1 4494162 YP_859434.1 CDS APECO1_2624 NC_008563.1 4334791 4335645 R transcriptional regulatory protein complement(4334791..4335645) Escherichia coli APEC O1 4494163 YP_859435.1 CDS rmuC NC_008563.1 4335775 4337202 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4335775..4337202 Escherichia coli APEC O1 4494168 YP_859436.1 CDS ubiE NC_008563.1 4337297 4338052 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4337297..4338052 Escherichia coli APEC O1 4494172 YP_859437.1 CDS yigP NC_008563.1 4338036 4338671 D hypothetical protein 4338036..4338671 Escherichia coli APEC O1 4494173 YP_859438.1 CDS ubiB NC_008563.1 4338668 4340308 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4338668..4340308 Escherichia coli APEC O1 4494174 YP_859439.1 CDS tatA NC_008563.1 4340345 4340656 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4340345..4340656 Escherichia coli APEC O1 4494175 YP_859440.1 CDS tatB NC_008563.1 4340660 4341175 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4340660..4341175 Escherichia coli APEC O1 4494176 YP_859441.1 CDS tatC NC_008563.1 4341178 4341954 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4341178..4341954 Escherichia coli APEC O1 4494177 YP_859442.1 CDS tatD NC_008563.1 4341984 4342778 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4341984..4342778 Escherichia coli APEC O1 4494178 YP_859443.1 CDS rfaH NC_008563.1 4342775 4343263 R transcriptional activator RfaH complement(4342775..4343263) Escherichia coli APEC O1 4494179 YP_859444.1 CDS ubiD NC_008563.1 4343430 4344923 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4343430..4344923 Escherichia coli APEC O1 4492836 YP_859445.1 CDS fre NC_008563.1 4344969 4345670 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4344969..4345670 Escherichia coli APEC O1 4492837 YP_859446.1 CDS fadA NC_008563.1 4345953 4347116 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4345953..4347116) Escherichia coli APEC O1 4492838 YP_859447.1 CDS fadB NC_008563.1 4347126 4349441 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4347126..4349441) Escherichia coli APEC O1 4492839 YP_859448.1 CDS pepQ NC_008563.1 4349505 4350836 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4349505..4350836 Escherichia coli APEC O1 4492840 YP_859449.1 CDS yigZ NC_008563.1 4350833 4351450 D hypothetical protein 4350833..4351450 Escherichia coli APEC O1 4492841 YP_859450.1 CDS trkH NC_008563.1 4351489 4352940 D potassium transporter 4351489..4352940 Escherichia coli APEC O1 4492842 YP_859451.1 CDS hemG NC_008563.1 4352952 4353497 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4352952..4353497 Escherichia coli APEC O1 4492843 YP_859453.1 CDS mobB NC_008563.1 4359077 4359604 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4359077..4359604) Escherichia coli APEC O1 4492845 YP_859454.1 CDS mobA NC_008563.1 4359586 4360170 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4359586..4360170) Escherichia coli APEC O1 4492846 YP_859455.1 CDS APECO1_2603 NC_008563.1 4360240 4360509 D hypothetical protein 4360240..4360509 Escherichia coli APEC O1 4492847 YP_859456.1 CDS yihE NC_008563.1 4360586 4361572 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4360586..4361572 Escherichia coli APEC O1 4492848 YP_859457.1 CDS dsbA NC_008563.1 4361589 4362215 D protein disulfide isomerase I 4361589..4362215 Escherichia coli APEC O1 4492849 YP_859458.1 CDS yihF NC_008563.1 4362328 4363800 D hypothetical protein 4362328..4363800 Escherichia coli APEC O1 4492850 YP_859459.1 CDS yihG NC_008563.1 4363841 4364773 R acyltransferase complement(4363841..4364773) Escherichia coli APEC O1 4492851 YP_859460.1 CDS polA NC_008563.1 4365137 4367923 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4365137..4367923 Escherichia coli APEC O1 4492852 YP_859461.1 CDS engB NC_008563.1 4368305 4368952 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4368305..4368952) Escherichia coli APEC O1 4492853 YP_859462.1 CDS yihI NC_008563.1 4369519 4370028 D hypothetical protein 4369519..4370028 Escherichia coli APEC O1 4492854 YP_859463.1 CDS hemN NC_008563.1 4370211 4371590 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4370211..4371590 Escherichia coli APEC O1 4493496 YP_859464.1 CDS glnG NC_008563.1 4371950 4373359 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4371950..4373359) Escherichia coli APEC O1 4493497 YP_859465.1 CDS glnL NC_008563.1 4373371 4374420 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4373371..4374420) Escherichia coli APEC O1 4493498 YP_859466.1 CDS glnA NC_008563.1 4374594 4376003 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4374594..4376003) Escherichia coli APEC O1 4493499 YP_859467.1 CDS bipA NC_008563.1 4376376 4378199 D GTP-binding protein 4376376..4378199 Escherichia coli APEC O1 4493500 YP_859468.1 CDS APECO1_2590 NC_008563.1 4378306 4379094 R similar to DNA-binding transcriptional regulator YihW; regulatory protein complement(4378306..4379094) Escherichia coli APEC O1 4493501 YP_859469.1 CDS APECO1_2589 NC_008563.1 4379134 4380081 R similar to ribokinase YihV; ribokinase family; hypothetical protein complement(4379134..4380081) Escherichia coli APEC O1 4493502 YP_859470.1 CDS APECO1_2588 NC_008563.1 4380133 4381080 D similar to oxidoreductase YihU; hypothetical protein 4380133..4381080 Escherichia coli APEC O1 4493503 YP_859471.1 CDS APECO1_2587 NC_008563.1 4381105 4381992 D hypothetical protein 4381105..4381992 Escherichia coli APEC O1 4493504 YP_859472.1 CDS APECO1_2586 NC_008563.1 4382025 4383035 D dehydrogenase 4382025..4383035 Escherichia coli APEC O1 4493505 YP_859473.1 CDS APECO1_2585 NC_008563.1 4383105 4384538 D major facilitator superfamily; hypothetical protein 4383105..4384538 Escherichia coli APEC O1 4493506 YP_859474.1 CDS APECO1_2584 NC_008563.1 4384637 4385986 D major facilitator superfamily; shikimate transporter 4384637..4385986 Escherichia coli APEC O1 4493507 YP_859475.1 CDS APECO1_2583 NC_008563.1 4385931 4386863 D hypothetical protein 4385931..4386863 Escherichia coli APEC O1 4493508 YP_859476.1 CDS APECO1_2582 NC_008563.1 4386983 4387603 D hydrolase; phosphatase 4386983..4387603 Escherichia coli APEC O1 4493509 YP_859477.1 CDS rbn NC_008563.1 4387597 4388469 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4387597..4388469 Escherichia coli APEC O1 4493510 YP_859478.1 CDS dtd NC_008563.1 4388466 4388903 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4388466..4388903 Escherichia coli APEC O1 4493511 YP_859479.1 CDS yiiD NC_008563.1 4388900 4389889 D acetyltransferase 4388900..4389889 Escherichia coli APEC O1 4493512 YP_859480.1 CDS APECO1_2578 NC_008563.1 4389953 4390936 R esterase/lipase/thioesterase domain; lipase complement(4389953..4390936) Escherichia coli APEC O1 4493513 YP_859481.1 CDS APECO1_2577 NC_008563.1 4391090 4391401 D hypothetical protein 4391090..4391401 Escherichia coli APEC O1 4493514 YP_859482.1 CDS APECO1_2576 NC_008563.1 4391402 4391692 D hypothetical protein 4391402..4391692 Escherichia coli APEC O1 4493515 YP_859483.1 CDS APECO1_2575 NC_008563.1 4392051 4392329 D hypothetical protein 4392051..4392329 Escherichia coli APEC O1 4495574 YP_859484.1 CDS fdhE NC_008563.1 4393159 4394088 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4393159..4394088) Escherichia coli APEC O1 4495575 YP_859485.1 CDS fdoI NC_008563.1 4394085 4394720 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4394085..4394720) Escherichia coli APEC O1 4495576 YP_859486.1 CDS fdoH NC_008563.1 4394717 4395619 R formate dehydrogenase-O, Fe-S subunit complement(4394717..4395619) Escherichia coli APEC O1 4495577 YP_859487.1 CDS fdoG NC_008563.1 4395632 4398046 R authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-O, large subunit complement(4395632..4398046) Escherichia coli APEC O1 4495578 YP_859488.1 CDS fdoG NC_008563.1 4398095 4398682 R authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-O, large subunit complement(4398095..4398682) Escherichia coli APEC O1 4495579 YP_859489.1 CDS fdhD NC_008563.1 4398876 4399709 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4398876..4399709 Escherichia coli APEC O1 4495580 YP_859490.1 CDS yiiG NC_008563.1 4400105 4400485 D hypothetical protein 4400105..4400485 Escherichia coli APEC O1 4495581 YP_859491.1 CDS APECO1_2568 NC_008563.1 4400839 4402233 D porin domain; glycoporin 4400839..4402233 Escherichia coli APEC O1 4495582 YP_859492.1 CDS yiiL NC_008563.1 4402274 4402588 R L-rhamnose mutarotase; hypothetical protein complement(4402274..4402588) Escherichia coli APEC O1 4495583 YP_859493.1 CDS rhaD NC_008563.1 4402598 4403422 R rhamnulose-1-phosphate aldolase complement(4402598..4403422) Escherichia coli APEC O1 4495584 YP_859494.1 CDS rhaA NC_008563.1 4403699 4404958 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4403699..4404958) Escherichia coli APEC O1 4495585 YP_859495.1 CDS rhaB NC_008563.1 4404955 4406424 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4404955..4406424) Escherichia coli APEC O1 4495586 YP_859496.1 CDS rhaS NC_008563.1 4406712 4407548 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4406712..4407548 Escherichia coli APEC O1 4495587 YP_859497.1 CDS rhaR NC_008563.1 4407532 4408470 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4407532..4408470 Escherichia coli APEC O1 4495588 YP_859498.1 CDS rhaT NC_008563.1 4408467 4409501 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4408467..4409501) Escherichia coli APEC O1 4495589 YP_859499.1 CDS sodA NC_008563.1 4409780 4410406 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4409780..4410406 Escherichia coli APEC O1 4494047 YP_859500.2 CDS kdgT NC_008563.1 4410666 4411649 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4410666..4411649 Escherichia coli APEC O1 4494048 YP_859501.1 CDS yiiM NC_008563.1 4411783 4412472 D hypothetical protein 4411783..4412472 Escherichia coli APEC O1 4494049 YP_859502.1 CDS cpxA NC_008563.1 4412578 4413951 R CpxA controls the expression of genes involved in protein folding and degradation; part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4412578..4413951) Escherichia coli APEC O1 4494050 YP_859503.1 CDS cpxR NC_008563.1 4413948 4414646 R CpxR controls the expression of genes involved in protein folding and degradation, DNA-binding response regulator in two-component regulatory system with CpxA; response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4413948..4414646) Escherichia coli APEC O1 4494051 YP_859504.1 CDS cpxP NC_008563.1 4414793 4415296 D periplasmic protein combats stress; repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4414793..4415296 Escherichia coli APEC O1 4494052 YP_859505.1 CDS fieF NC_008563.1 4415445 4416347 D transport function, CDF family; member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4415445..4416347 Escherichia coli APEC O1 4494053 YP_859506.1 CDS pfkA NC_008563.1 4416468 4417490 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4416468..4417490 Escherichia coli APEC O1 4494054 YP_859507.1 CDS sbp NC_008563.1 4417810 4418799 D sulfate transporter subunit 4417810..4418799 Escherichia coli APEC O1 4494055 YP_859508.1 CDS cdh NC_008563.1 4418717 4419661 D CDP-diacylglycerol pyrophosphatase 4418717..4419661 Escherichia coli APEC O1 4494056 YP_859509.1 CDS tpiA NC_008563.1 4419716 4420483 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4419716..4420483) Escherichia coli APEC O1 4494057 YP_859510.1 CDS yiiQ NC_008563.1 4420591 4421190 R hypothetical protein complement(4420591..4421190) Escherichia coli APEC O1 4494058 YP_859511.1 CDS yiiR NC_008563.1 4421291 4421731 D hypothetical protein 4421291..4421731 Escherichia coli APEC O1 4494059 YP_859512.1 CDS yiiS NC_008563.1 4421943 4422242 D hypothetical protein 4421943..4422242 Escherichia coli APEC O1 4494060 YP_859513.1 CDS yiiT NC_008563.1 4422269 4422697 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4422269..4422697 Escherichia coli APEC O1 4494972 YP_859514.1 CDS fpr NC_008563.1 4422702 4423448 R ferredoxin-NADP reductase complement(4422702..4423448) Escherichia coli APEC O1 4494973 YP_859515.1 CDS glpX NC_008563.1 4423545 4424555 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4423545..4424555) Escherichia coli APEC O1 4494974 YP_859516.1 CDS glpK NC_008563.1 4424726 4426255 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4424726..4426255) Escherichia coli APEC O1 4494975 YP_859517.1 CDS glpF NC_008563.1 4426257 4427102 R glycerol uptake facilitator protein complement(4426257..4427102) Escherichia coli APEC O1 4494976 YP_859518.1 CDS APECO1_2541 NC_008563.1 4427914 4428420 D hypothetical protein 4427914..4428420 Escherichia coli APEC O1 4494977 YP_859519.1 CDS menA NC_008563.1 4428435 4429361 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4428435..4429361) Escherichia coli APEC O1 4494978 YP_859520.1 CDS hslU NC_008563.1 4429428 4430759 R heat shock protein, homologous to chaperones; heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4429428..4430759) Escherichia coli APEC O1 4494979 YP_859521.1 CDS hslV NC_008563.1 4430769 4431299 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4430769..4431299) Escherichia coli APEC O1 4494980 YP_859522.1 CDS ftsN NC_008563.1 4431392 4432351 R cell division protein FtsN complement(4431392..4432351) Escherichia coli APEC O1 4494981 YP_859523.1 CDS cytR NC_008563.1 4432443 4433474 R regulator for deo operon, udp, cdd, tsx, nupC, and nupG; negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4432443..4433474) Escherichia coli APEC O1 4494982 YP_859524.1 CDS priA NC_008563.1 4433624 4435894 R primosomal protein N' (factor Y) directs replication fork assembly at D-loops, ATP-dependent; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4433624..4435894) Escherichia coli APEC O1 4494983 YP_859525.1 CDS yliX NC_008563.1 4436298 4436906 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4436298..4436906) Escherichia coli APEC O1 4494984 YP_859526.1 CDS metJ NC_008563.1 4436966 4437421 R repressor of all met genes but metF; when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4436966..4437421) Escherichia coli APEC O1 4494985 YP_859527.1 CDS metB NC_008563.1 4437506 4438720 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4437506..4438720 Escherichia coli APEC O1 4494986 YP_859528.1 CDS metL NC_008563.1 4438723 4441155 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4438723..4441155 Escherichia coli APEC O1 4494987 YP_859529.1 CDS tsx NC_008563.1 4441373 4442233 R nucleoside-specific channel-forming protein Tsx precursor complement(4441373..4442233) Escherichia coli APEC O1 4494988 YP_859530.1 CDS APECO1_2529 NC_008563.1 4442310 4443935 R metallophosphoesterase; hypothetical protein complement(4442310..4443935) Escherichia coli APEC O1 4494989 YP_859531.1 CDS APECO1_2528 NC_008563.1 4443970 4445523 R dihydroorotase; hypothetical protein complement(4443970..4445523) Escherichia coli APEC O1 4494990 YP_859532.1 CDS APECO1_2527 NC_008563.1 4445753 4446877 R hypothetical protein complement(4445753..4446877) Escherichia coli APEC O1 4491557 YP_859533.1 CDS APECO1_2526 NC_008563.1 4447010 4448563 D 5'-nucleotidase 4447010..4448563 Escherichia coli APEC O1 4491558 YP_859534.1 CDS metF NC_008563.1 4448945 4449835 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4448945..4449835 Escherichia coli APEC O1 4491559 YP_859535.1 CDS katG NC_008563.1 4450164 4452344 D catalase/hydroperoxidase HPI(I) 4450164..4452344 Escherichia coli APEC O1 4491560 YP_859536.1 CDS yijE NC_008563.1 4452372 4453343 D permease 4452372..4453343 Escherichia coli APEC O1 4491561 YP_859537.1 CDS yijF NC_008563.1 4453370 4453987 R hypothetical protein complement(4453370..4453987) Escherichia coli APEC O1 4491562 YP_859538.1 CDS gldA NC_008563.1 4454263 4455405 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4454263..4455405) Escherichia coli APEC O1 4491563 YP_859539.1 CDS fsaB NC_008563.1 4455377 4456039 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4455377..4456039) Escherichia coli APEC O1 4491564 YP_859540.1 CDS ptsA NC_008563.1 4456051 4458552 R PTS family Hpr; phosphoenolpyruvate-protein phosphotransferase PtsA complement(4456051..4458552) Escherichia coli APEC O1 4491565 YP_859541.1 CDS fruA NC_008563.1 4458861 4459940 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4458861..4459940 Escherichia coli APEC O1 4491566 YP_859542.1 CDS APECO1_2517 NC_008563.1 4459988 4460314 R hypothetical protein complement(4459988..4460314) Escherichia coli APEC O1 4491567 YP_859543.1 CDS pflD NC_008563.1 4460326 4462623 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4460326..4462623 Escherichia coli APEC O1 4491568 YP_859544.1 CDS pflC NC_008563.1 4462520 4463467 D pyruvate formate lyase II activase 4462520..4463467 Escherichia coli APEC O1 4491569 YP_859545.2 CDS frwD NC_008563.1 4463469 4463810 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4463469..4463810 Escherichia coli APEC O1 4491570 YP_859546.1 CDS yijO NC_008563.1 4463797 4464648 R DNA-binding transcriptional regulator complement(4463797..4464648) Escherichia coli APEC O1 4491571 YP_859547.1 CDS yjjP NC_008563.1 4464874 4466607 R sulfatase; hypothetical protein complement(4464874..4466607) Escherichia coli APEC O1 4491572 YP_859548.1 CDS ppc NC_008563.1 4466790 4469441 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4466790..4469441) Escherichia coli APEC O1 4491573 YP_859549.1 CDS argE NC_008563.1 4469743 4470933 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4469743..4470933) Escherichia coli APEC O1 4491574 YP_859550.1 CDS argC NC_008563.1 4471048 4472052 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4471048..4472052 Escherichia coli APEC O1 4491575 YP_859551.1 CDS argB NC_008563.1 4472027 4472836 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4472027..4472836 Escherichia coli APEC O1 4491576 YP_859552.1 CDS argH NC_008563.1 4472897 4474270 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4472897..4474270 Escherichia coli APEC O1 4491440 YP_859553.1 CDS rspA NC_008563.1 4474708 4475982 D starvation sensing protein RspA 4474708..4475982 Escherichia coli APEC O1 4491441 YP_859554.1 CDS yjjL NC_008563.1 4476049 4477332 D major facilitator superfamily; hypothetical protein 4476049..4477332 Escherichia coli APEC O1 4491442 YP_859555.1 CDS oxyR NC_008563.1 4477539 4478501 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4477539..4478501 Escherichia coli APEC O1 4491443 YP_859556.1 CDS udhA NC_008563.1 4478484 4479884 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4478484..4479884) Escherichia coli APEC O1 4491444 YP_859557.1 CDS APECO1_2502 NC_008563.1 4480214 4481380 D hippuricase 4480214..4481380 Escherichia coli APEC O1 4491445 YP_859558.1 CDS APECO1_2501 NC_008563.1 4481423 4482739 D transporter 4481423..4482739 Escherichia coli APEC O1 4491446 YP_859559.1 CDS yijC NC_008563.1 4482789 4483493 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4482789..4483493 Escherichia coli APEC O1 4491447 YP_859560.1 CDS yijD NC_008563.1 4483493 4483852 D hypothetical protein 4483493..4483852 Escherichia coli APEC O1 4491448 YP_859561.1 CDS trmA NC_008563.1 4483892 4484992 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4483892..4484992) Escherichia coli APEC O1 4491449 YP_859562.2 CDS btuB NC_008563.1 4485361 4487205 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4485361..4487205 Escherichia coli APEC O1 4491450 YP_859563.2 CDS murI NC_008563.1 4487150 4488007 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4487150..4488007 Escherichia coli APEC O1 4491451 YP_859564.1 CDS murB NC_008563.1 4493638 4494666 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4493638..4494666 Escherichia coli APEC O1 4491452 YP_859565.1 CDS birA NC_008563.1 4494663 4495628 D biotin ligase; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4494663..4495628 Escherichia coli APEC O1 4491453 YP_859566.1 CDS coaA NC_008563.1 4495657 4496628 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4495657..4496628) Escherichia coli APEC O1 4491454 YP_859567.1 CDS tufA NC_008563.1 4497525 4498709 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4497525..4498709 Escherichia coli APEC O1 4491455 YP_859568.1 CDS secE NC_008563.1 4498939 4499322 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4498939..4499322 Escherichia coli APEC O1 4491456 YP_859569.1 CDS nusG NC_008563.1 4499324 4499869 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4499324..4499869 Escherichia coli APEC O1 4491457 YP_859570.1 CDS APECO1_2489 NC_008563.1 4499974 4500975 R hypothetical protein complement(4499974..4500975) Escherichia coli APEC O1 4491458 YP_004770506.1 CDS APECO1_p1 NC_008563.1 4500028 4500456 D 50S ribosomal protein L11 4500028..4500456 Escherichia coli APEC O1 11031901 YP_004770507.1 CDS APECO1_p2 NC_008563.1 4500460 4501164 D 50S ribosomal protein L1 4500460..4501164 Escherichia coli APEC O1 11031903 YP_859571.1 CDS rplJ NC_008563.1 4501456 4501953 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4501456..4501953 Escherichia coli APEC O1 4493792 YP_859572.1 CDS APECO1_2487 NC_008563.1 4502005 4502445 R hypothetical protein complement(4502005..4502445) Escherichia coli APEC O1 4493793 YP_859573.1 CDS rpoB NC_008563.1 4502672 4506733 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4502672..4506733 Escherichia coli APEC O1 4493794 YP_859574.1 CDS rpoC NC_008563.1 4506810 4511033 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4506810..4511033 Escherichia coli APEC O1 4493795 YP_859575.1 CDS thiH NC_008563.1 4511273 4512406 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4511273..4512406) Escherichia coli APEC O1 4493796 YP_859576.2 CDS thiG NC_008563.1 4512403 4513173 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4512403..4513173) Escherichia coli APEC O1 4493798 YP_859577.1 CDS thiF NC_008563.1 4513359 4514207 R thiazole biosynthesis protein ThiF complement(4513359..4514207) Escherichia coli APEC O1 4493799 YP_859578.1 CDS thiE NC_008563.1 4514107 4514742 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4514107..4514742) Escherichia coli APEC O1 4493800 YP_859579.1 CDS thiC NC_008563.1 4514742 4516637 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4514742..4516637) Escherichia coli APEC O1 4493801 YP_859580.1 CDS yjaE NC_008563.1 4516870 4517346 R Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ; binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4516870..4517346) Escherichia coli APEC O1 4493802 YP_859581.1 CDS nudC NC_008563.1 4517441 4518214 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4517441..4518214 Escherichia coli APEC O1 4493803 YP_859582.1 CDS hemE NC_008563.1 4518254 4519318 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4518254..4519318 Escherichia coli APEC O1 4493804 YP_859583.1 CDS nfi NC_008563.1 4519328 4519999 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4519328..4519999 Escherichia coli APEC O1 4493805 YP_859584.1 CDS yjaG NC_008563.1 4520042 4520632 D hypothetical protein 4520042..4520632 Escherichia coli APEC O1 4493806 YP_859585.1 CDS APECO1_2475 NC_008563.1 4520819 4521091 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4520819..4521091 Escherichia coli APEC O1 4493807 YP_859586.1 CDS yjaH NC_008563.1 4521098 4521799 D hypothetical protein 4521098..4521799 Escherichia coli APEC O1 4493808 YP_859587.1 CDS zraP NC_008563.1 4521801 4522361 R zinc resistance protein complement(4521801..4522361) Escherichia coli APEC O1 4493809 YP_859588.1 CDS zraS NC_008563.1 4522458 4523834 D sensor protein ZraS 4522458..4523834 Escherichia coli APEC O1 4493810 YP_859589.1 CDS zraR NC_008563.1 4523831 4525156 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4523831..4525156 Escherichia coli APEC O1 4493811 YP_859590.1 CDS purD NC_008563.1 4525153 4526442 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4525153..4526442) Escherichia coli APEC O1 4492855 YP_859591.1 CDS purH NC_008563.1 4526454 4528043 R purine biosynthesis; involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4526454..4528043) Escherichia coli APEC O1 4492856 YP_859592.1 CDS APECO1_2468 NC_008563.1 4528359 4528619 R hypothetical protein complement(4528359..4528619) Escherichia coli APEC O1 4492857 YP_859595.1 CDS yjaA NC_008563.1 4533761 4534144 D hypothetical protein 4533761..4534144 Escherichia coli APEC O1 4492860 YP_859596.1 CDS yjaB NC_008563.1 4534208 4534651 R acetyltransferase (GNAT) family; hypothetical protein complement(4534208..4534651) Escherichia coli APEC O1 4492861 YP_859597.1 CDS metA NC_008563.1 4534808 4535737 D acyltransferase activity; catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4534808..4535737 Escherichia coli APEC O1 4492862 YP_859598.1 CDS aceB NC_008563.1 4535988 4537607 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4535988..4537607 Escherichia coli APEC O1 4492863 YP_859599.1 CDS aceA NC_008563.1 4537622 4538941 D isocitrate lyase 4537622..4538941 Escherichia coli APEC O1 4492864 YP_859600.1 CDS aceK NC_008563.1 4538990 4540714 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4538990..4540714 Escherichia coli APEC O1 4492865 YP_859601.1 CDS iclR NC_008563.1 4540731 4541594 R bacterial regulatory protein; regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4540731..4541594) Escherichia coli APEC O1 4492866 YP_859602.1 CDS metH NC_008563.1 4541740 4545438 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4541740..4545438 Escherichia coli APEC O1 4492867 YP_859603.1 CDS APECO1_2457 NC_008563.1 4545498 4545818 D hypothetical protein 4545498..4545818 Escherichia coli APEC O1 4492868 YP_859604.1 CDS APECO1_2456 NC_008563.1 4545861 4546310 D hypothetical protein 4545861..4546310 Escherichia coli APEC O1 4492869 YP_859605.1 CDS yjbB NC_008563.1 4546481 4548112 D hypothetical protein 4546481..4548112 Escherichia coli APEC O1 4492870 YP_859606.1 CDS pepE NC_008563.1 4548202 4548891 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4548202..4548891) Escherichia coli APEC O1 4492871 YP_859607.1 CDS APECO1_2453 NC_008563.1 4549273 4550514 R L-sorbose-1-P-reductase complement(4549273..4550514) Escherichia coli APEC O1 4492872 YP_859608.1 CDS APECO1_2452 NC_008563.1 4550554 4551396 R PTS system mannose-specific transporter subunit IID complement(4550554..4551396) Escherichia coli APEC O1 4492873 YP_859609.1 CDS sorA NC_008563.1 4551389 4552186 R sorbose-permease PTS system IIC component SorA complement(4551389..4552186) Escherichia coli APEC O1 4493985 YP_859610.1 CDS APECO1_2450 NC_008563.1 4552252 4552746 R PTS system, sorbose-specific IIB component complement(4552252..4552746) Escherichia coli APEC O1 4493986 YP_859611.1 CDS APECO1_2449 NC_008563.1 4552746 4553153 R sorbose PTS component complement(4552746..4553153) Escherichia coli APEC O1 4493987 YP_859612.1 CDS APECO1_2448 NC_008563.1 4553163 4553969 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4553163..4553969) Escherichia coli APEC O1 4493988 YP_859613.1 CDS APECO1_2447 NC_008563.1 4554039 4555031 R transcriptional regulator of sorbose uptake and utilization genes complement(4554039..4555031) Escherichia coli APEC O1 4493989 YP_859614.1 CDS yjbC NC_008563.1 4555334 4556206 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4555334..4556206 Escherichia coli APEC O1 4493990 YP_859615.1 CDS yjbD NC_008563.1 4556207 4556479 R hypothetical protein complement(4556207..4556479) Escherichia coli APEC O1 4493991 YP_859616.1 CDS lysC NC_008563.1 4556732 4558081 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(4556732..4558081) Escherichia coli APEC O1 4493992 YP_859617.1 CDS pgi NC_008563.1 4558606 4560255 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4558606..4560255 Escherichia coli APEC O1 4493993 YP_859619.1 CDS yjbF NC_008563.1 4561080 4561748 D hypothetical protein 4561080..4561748 Escherichia coli APEC O1 4493995 YP_859620.1 CDS yjbG NC_008563.1 4561745 4562482 D hypothetical protein 4561745..4562482 Escherichia coli APEC O1 4493996 YP_859621.1 CDS yjbH NC_008563.1 4562482 4564578 D hypothetical protein 4562482..4564578 Escherichia coli APEC O1 4493997 YP_859622.1 CDS APECO1_2438 NC_008563.1 4564625 4564903 R hypothetical protein complement(4564625..4564903) Escherichia coli APEC O1 4493998 YP_859623.1 CDS yjbE NC_008563.1 4565118 4565528 D phosphate-starvation-inducible protein PsiE 4565118..4565528 Escherichia coli APEC O1 4493999 YP_859624.1 CDS malG NC_008563.1 4565622 4566512 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4565622..4566512) Escherichia coli APEC O1 4494000 YP_859625.1 CDS malF NC_008563.1 4566527 4568086 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4566527..4568086) Escherichia coli APEC O1 4494001 YP_859626.1 CDS malE NC_008563.1 4568225 4569415 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4568225..4569415) Escherichia coli APEC O1 4494002 YP_859627.1 CDS malK NC_008563.1 4569690 4570895 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4569690..4570895 Escherichia coli APEC O1 4494003 YP_859628.1 CDS lamB NC_008563.1 4570967 4572307 D porin involved in the transport of maltose and maltodextrins; maltoporin 4570967..4572307 Escherichia coli APEC O1 4494004 YP_859629.1 CDS malM NC_008563.1 4572621 4573550 D maltose regulon periplasmic protein 4572621..4573550 Escherichia coli APEC O1 4493029 YP_859630.1 CDS ubiC NC_008563.1 4573729 4574226 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4573729..4574226 Escherichia coli APEC O1 4493030 YP_859631.1 CDS ubiA NC_008563.1 4574239 4575111 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4574239..4575111 Escherichia coli APEC O1 4493031 YP_859632.1 CDS plsB NC_008563.1 4575264 4577747 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4575264..4577747) Escherichia coli APEC O1 4493032 YP_859633.1 CDS dgkA NC_008563.1 4577858 4578226 D diacylglycerol kinase DgkA 4577858..4578226 Escherichia coli APEC O1 4493033 YP_859634.1 CDS lexA NC_008563.1 4578336 4578944 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4578336..4578944 Escherichia coli APEC O1 4493034 YP_859635.1 CDS dinF NC_008563.1 4578963 4580342 D DNA-damage-inducible SOS response protein 4578963..4580342 Escherichia coli APEC O1 4493035 YP_859636.1 CDS yjbK NC_008563.1 4580709 4581395 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4580709..4581395) Escherichia coli APEC O1 4493036 YP_859637.1 CDS yjbN NC_008563.1 4581380 4582375 D tRNA-dihydrouridine synthase A 4581380..4582375 Escherichia coli APEC O1 4493037 YP_859638.1 CDS pspG NC_008563.1 4582299 4582751 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4582299..4582751 Escherichia coli APEC O1 4493038 YP_859639.1 CDS qor NC_008563.1 4582916 4583899 R quinone oxidoreductase complement(4582916..4583899) Escherichia coli APEC O1 4493039 YP_859640.1 CDS APECO1_2420 NC_008563.1 4584005 4586125 R oxidoreductase complement(4584005..4586125) Escherichia coli APEC O1 4493040 YP_859641.1 CDS APECO1_2419 NC_008563.1 4586043 4587443 R transmembrane transport protein complement(4586043..4587443) Escherichia coli APEC O1 4493041 YP_859642.1 CDS APECO1_2418 NC_008563.1 4587534 4588313 R enoyl-CoA hydratase/isomerase family protein complement(4587534..4588313) Escherichia coli APEC O1 4493042 YP_859643.1 CDS APECO1_2417 NC_008563.1 4588306 4589877 R propionate CoA-transferase complement(4588306..4589877) Escherichia coli APEC O1 4493043 YP_859644.1 CDS APECO1_2416 NC_008563.1 4590133 4591167 D LacI family transcriptional regulator 4590133..4591167 Escherichia coli APEC O1 4493044 YP_859645.1 CDS dnaB NC_008563.1 4591240 4592655 D unwinds double stranded DNA; replicative DNA helicase 4591240..4592655 Escherichia coli APEC O1 4493045 YP_859646.1 CDS alr NC_008563.1 4592708 4593787 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4592708..4593787 Escherichia coli APEC O1 4493046 YP_859647.1 CDS APECO1_2413 NC_008563.1 4593810 4594367 D transporter 4593810..4594367 Escherichia coli APEC O1 4493047 YP_859648.1 CDS APECO1_2412 NC_008563.1 4594340 4595362 D NadR transcriptional repressor / NMN adenylyltransferase 4594340..4595362 Escherichia coli APEC O1 4492658 YP_859649.1 CDS tyrB NC_008563.1 4595444 4596637 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4595444..4596637 Escherichia coli APEC O1 4492659 YP_859650.1 CDS sucA NC_008563.1 4596819 4599563 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 4596819..4599563 Escherichia coli APEC O1 4492660 YP_859651.1 CDS APECO1_2409 NC_008563.1 4599596 4600750 D dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 4599596..4600750 Escherichia coli APEC O1 4492661 YP_859652.1 CDS APECO1_2408 NC_008563.1 4600762 4602180 D subunit of 2-oxoglutarate dehydrogenase 4600762..4602180 Escherichia coli APEC O1 4492662 YP_859653.1 CDS sucC NC_008563.1 4602202 4603371 D SucC, succinyl-CoA synthetase beta chain 4602202..4603371 Escherichia coli APEC O1 4492663 YP_859654.1 CDS APECO1_2406 NC_008563.1 4603384 4604256 D succinyl-CoA synthetase subunit alpha 4603384..4604256 Escherichia coli APEC O1 4492664 YP_859655.1 CDS APECO1_2405 NC_008563.1 4604462 4605967 D membrane-bound protein 4604462..4605967 Escherichia coli APEC O1 4492665 YP_859656.1 CDS APECO1_2404 NC_008563.1 4605841 4607052 D lactate dehydrogenase 4605841..4607052 Escherichia coli APEC O1 4492666 YP_859657.1 CDS APECO1_2403 NC_008563.1 4607041 4608399 R two component response regulator complement(4607041..4608399) Escherichia coli APEC O1 4492667 YP_859658.1 CDS APECO1_2402 NC_008563.1 4608392 4610212 R transport sensor protein complement(4608392..4610212) Escherichia coli APEC O1 4492668 YP_859659.1 CDS aphA NC_008563.1 4610420 4611202 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4610420..4611202 Escherichia coli APEC O1 4492669 YP_859660.1 CDS yjbQ NC_008563.1 4611313 4611729 D hypothetical protein 4611313..4611729 Escherichia coli APEC O1 4492670 YP_859661.1 CDS yjbR NC_008563.1 4611733 4612089 D hypothetical protein 4611733..4612089 Escherichia coli APEC O1 4492671 YP_859662.1 CDS uvrA NC_008563.1 4612124 4614946 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4612124..4614946) Escherichia coli APEC O1 4492672 YP_859663.2 CDS ssb NC_008563.1 4615200 4615736 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4615200..4615736 Escherichia coli APEC O1 4492673 YP_859664.1 CDS yjcB NC_008563.1 4615835 4616185 R hypothetical protein complement(4615835..4616185) Escherichia coli APEC O1 4492674 YP_859665.1 CDS yjcC NC_008563.1 4616545 4618131 D signal transduction protein YjcC 4616545..4618131 Escherichia coli APEC O1 4492675 YP_859666.1 CDS soxR NC_008563.1 4618543 4619007 D redox-sensitive transcriptional activator SoxR 4618543..4619007 Escherichia coli APEC O1 4492676 YP_859667.1 CDS yjcD NC_008563.1 4619554 4620903 D xanthine/uracil permeases family protein YjcD 4619554..4620903 Escherichia coli APEC O1 4492677 YP_859668.1 CDS yjcE NC_008563.1 4621054 4622703 D sodium/hydrogen exchanger family protein YjcE 4621054..4622703 Escherichia coli APEC O1 4493379 YP_859669.1 CDS APECO1_2391 NC_008563.1 4622739 4623623 R LysR family transcriptional regulator complement(4622739..4623623) Escherichia coli APEC O1 4493380 YP_859670.1 CDS APECO1_2390 NC_008563.1 4623727 4624137 D murein hydrolase exporter 4623727..4624137 Escherichia coli APEC O1 4493381 YP_859671.1 CDS APECO1_2389 NC_008563.1 4624130 4624819 D LrgB family murein hydrolase regulator 4624130..4624819 Escherichia coli APEC O1 4493382 YP_859672.1 CDS actP NC_008563.1 4624858 4626507 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4624858..4626507) Escherichia coli APEC O1 4493383 YP_859673.1 CDS yjcH NC_008563.1 4626504 4626821 R hypothetical protein complement(4626504..4626821) Escherichia coli APEC O1 4493384 YP_859674.1 CDS acs NC_008563.1 4627110 4629068 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4627110..4629068) Escherichia coli APEC O1 4493385 YP_859675.1 CDS nrfA NC_008563.1 4629460 4630896 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4629460..4630896 Escherichia coli APEC O1 4493386 YP_859676.1 CDS nrfB NC_008563.1 4630935 4631507 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4630935..4631507 Escherichia coli APEC O1 4493387 YP_859677.1 CDS nrfC NC_008563.1 4631504 4632175 D formate-dependent nitire reductase subunit NrfC 4631504..4632175 Escherichia coli APEC O1 4493388 YP_859678.1 CDS nrfD NC_008563.1 4632172 4633128 D formate-dependent nitrite reductase, membrane subunit NrfD 4632172..4633128 Escherichia coli APEC O1 4493389 YP_859679.1 CDS nrfE NC_008563.1 4633208 4634866 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4633208..4634866 Escherichia coli APEC O1 4493390 YP_859680.1 CDS nrfG NC_008563.1 4635173 4635835 D formate-dependent nitrite reductase complex subunit NrfG 4635173..4635835 Escherichia coli APEC O1 4493391 YP_859681.1 CDS gltP NC_008563.1 4636178 4637491 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4636178..4637491 Escherichia coli APEC O1 4493392 YP_859682.1 CDS yjcO NC_008563.1 4637639 4638328 R hypothetical protein complement(4637639..4638328) Escherichia coli APEC O1 4493393 YP_859683.1 CDS yddO NC_008563.1 4638439 4639143 R ABC transporter ATP-binding protein complement(4638439..4639143) Escherichia coli APEC O1 4493394 YP_859684.1 CDS yddP NC_008563.1 4639130 4639999 R ABC transporter transporter ATP-binding protein complement(4639130..4639999) Escherichia coli APEC O1 4493395 YP_859685.1 CDS yddQ NC_008563.1 4639959 4640792 R ABC transporter permease complement(4639959..4640792) Escherichia coli APEC O1 4493396 YP_859686.1 CDS yddR NC_008563.1 4640792 4641934 R ABC transporter permease complement(4640792..4641934) Escherichia coli APEC O1 4493397 YP_859687.1 CDS APECO1_2373 NC_008563.1 4641941 4643509 R ABC transporter periplasmic oligo-dipeptide/nickel binding protein complement(4641941..4643509) Escherichia coli APEC O1 4493106 YP_859688.1 CDS fdhF NC_008563.1 4643884 4645563 R authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-H, selenopolypeptide subunit complement(4643884..4645563) Escherichia coli APEC O1 4493107 YP_859689.1 CDS fdhF NC_008563.1 4645612 4646031 R authentic frameshift, identical to Escherichia coli UTI89; formate dehydrogenase-H, selenopolypeptide subunit complement(4645612..4646031) Escherichia coli APEC O1 4493108 YP_859690.1 CDS yjcP NC_008563.1 4646229 4647695 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(4646229..4647695) Escherichia coli APEC O1 4493109 YP_859691.1 CDS yjcQ NC_008563.1 4647692 4649743 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4647692..4649743) Escherichia coli APEC O1 4493110 YP_859692.1 CDS yjcR NC_008563.1 4649743 4650774 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4649743..4650774) Escherichia coli APEC O1 4493111 YP_859693.1 CDS APECO1_2368 NC_008563.1 4650793 4651068 R hypothetical protein complement(4650793..4651068) Escherichia coli APEC O1 4493112 YP_859694.1 CDS yjcS NC_008563.1 4651276 4653273 R hypothetical protein complement(4651276..4653273) Escherichia coli APEC O1 4493113 YP_859695.1 CDS yjcT NC_008563.1 4653536 4654465 R D-allose kinase complement(4653536..4654465) Escherichia coli APEC O1 4493114 YP_859696.1 CDS yjcU NC_008563.1 4654449 4655144 R allulose-6-phosphate 3-epimerase complement(4654449..4655144) Escherichia coli APEC O1 4493115 YP_859697.1 CDS alsC NC_008563.1 4655155 4655862 R D-allose transport system permease protein AlsC complement(4655155..4655862) Escherichia coli APEC O1 4493116 YP_859698.1 CDS alsA NC_008563.1 4656114 4657646 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4656114..4657646) Escherichia coli APEC O1 4493117 YP_859699.1 CDS APECO1_2362 NC_008563.1 4657773 4658714 R D-allose transporter subunit complement(4657773..4658714) Escherichia coli APEC O1 4493118 YP_859700.1 CDS rpiR NC_008563.1 4658767 4659690 R involved in rpiB and als operon repression; RpiR family transcriptional regulator complement(4658767..4659690) Escherichia coli APEC O1 4493119 YP_859701.1 CDS rpiB NC_008563.1 4660016 4660465 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4660016..4660465 Escherichia coli APEC O1 4493120 YP_859702.1 CDS APECO1_2359 NC_008563.1 4660534 4660863 D hypothetical protein 4660534..4660863 Escherichia coli APEC O1 4493121 YP_859703.1 CDS phnP NC_008563.1 4660891 4661649 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4660891..4661649) Escherichia coli APEC O1 4493122 YP_859704.1 CDS phnO NC_008563.1 4661651 4662085 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4661651..4662085) Escherichia coli APEC O1 4493123 YP_859705.1 CDS phnN NC_008563.1 4662072 4662629 R ribose 1,5-bisphosphokinase complement(4662072..4662629) Escherichia coli APEC O1 4493124 YP_859706.1 CDS phnM NC_008563.1 4662629 4663765 R carbon-phosphorus lyase complex subunit PhnM complement(4662629..4663765) Escherichia coli APEC O1 4493125 YP_859707.1 CDS phnL NC_008563.1 4663762 4664541 R phosphonates transport ATP-binding protein PhnL complement(4663762..4664541) Escherichia coli APEC O1 4492894 YP_859708.1 CDS phnK NC_008563.1 4664553 4665311 R phosphonate C-P lyase system protein PhnK complement(4664553..4665311) Escherichia coli APEC O1 4492895 YP_859709.1 CDS phnJ NC_008563.1 4665410 4666081 D carbon-phosphorus lyase complex subunit PhnJ 4665410..4666081 Escherichia coli APEC O1 4492896 YP_859710.1 CDS phnI NC_008563.1 4666146 4667216 R carbon-phosphorus lyase complex subunit PhnI complement(4666146..4667216) Escherichia coli APEC O1 4492897 YP_859711.1 CDS phnH NC_008563.1 4667210 4667794 R carbon-phosphorus lyase complex subunit complement(4667210..4667794) Escherichia coli APEC O1 4492898 YP_859712.1 CDS phnG NC_008563.1 4667791 4668243 R carbon-phosphorus lyase complex subunit PhnG complement(4667791..4668243) Escherichia coli APEC O1 4492899 YP_859713.1 CDS phnF NC_008563.1 4668244 4668975 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4668244..4668975) Escherichia coli APEC O1 4492900 YP_859714.1 CDS phnE NC_008563.1 4668990 4669832 R alkylphosphonate ABC transporter subunit PhnE complement(4668990..4669832) Escherichia coli APEC O1 4492901 YP_859715.1 CDS phnD NC_008563.1 4669875 4670891 R alkylphosphonate ABC transporter subunit PhnD complement(4669875..4670891) Escherichia coli APEC O1 4492902 YP_859716.1 CDS phnC NC_008563.1 4670916 4671704 R phosphonate/organophosphate ester transporter subunit complement(4670916..4671704) Escherichia coli APEC O1 4492903 YP_859717.1 CDS phnB NC_008563.1 4671837 4672280 R hypothetical protein complement(4671837..4672280) Escherichia coli APEC O1 4492904 YP_859718.1 CDS APECO1_2343 NC_008563.1 4672335 4672769 D hypothetical protein 4672335..4672769 Escherichia coli APEC O1 4492905 YP_859719.1 CDS yjdA NC_008563.1 4673178 4675406 D hypothetical protein 4673178..4675406 Escherichia coli APEC O1 4492906 YP_859720.1 CDS yjcZ NC_008563.1 4675436 4676281 D hypothetical protein 4675436..4676281 Escherichia coli APEC O1 4492907 YP_859721.1 CDS proP NC_008563.1 4676545 4678047 D proline/glycine betaine transporter 4676545..4678047 Escherichia coli APEC O1 4492908 YP_859722.1 CDS basS NC_008563.1 4678224 4679315 R sensor protein BasS/PmrB complement(4678224..4679315) Escherichia coli APEC O1 4492909 YP_859723.1 CDS basR NC_008563.1 4679325 4679993 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4679325..4679993) Escherichia coli APEC O1 4492910 YP_859724.1 CDS yjdB NC_008563.1 4679990 4681663 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4679990..4681663) Escherichia coli APEC O1 4492911 YP_859725.1 CDS yjdE NC_008563.1 4681737 4683074 R arginine:agmatin antiporter complement(4681737..4683074) Escherichia coli APEC O1 4492912 YP_859726.1 CDS adiY NC_008563.1 4683211 4683972 R regulatory protein AdiY complement(4683211..4683972) Escherichia coli APEC O1 4494565 YP_859727.1 CDS adiA NC_008563.1 4684308 4686578 R biodegradative arginine decarboxylase complement(4684308..4686578) Escherichia coli APEC O1 4494566 YP_859728.1 CDS melR NC_008563.1 4686774 4687682 R DNA-binding transcriptional regulator MelR complement(4686774..4687682) Escherichia coli APEC O1 4494567 YP_859729.1 CDS melA NC_008563.1 4687965 4689320 D alpha-galactosidase 4687965..4689320 Escherichia coli APEC O1 4494568 YP_859730.1 CDS yjdF NC_008563.1 4689317 4689967 R hypothetical protein complement(4689317..4689967) Escherichia coli APEC O1 4494569 YP_859731.1 CDS fumB NC_008563.1 4690090 4691736 R anaerobic class I fumarate hydratase complement(4690090..4691736) Escherichia coli APEC O1 4494570 YP_859732.1 CDS dcuB NC_008563.1 4691814 4693154 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4691814..4693154) Escherichia coli APEC O1 4494571 YP_859733.1 CDS yjdG NC_008563.1 4693725 4694444 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DcuR family transcriptional regulator complement(4693725..4694444) Escherichia coli APEC O1 4494572 YP_859734.1 CDS yjdH NC_008563.1 4694441 4696072 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4694441..4696072) Escherichia coli APEC O1 4494573 YP_859735.1 CDS yjdJ NC_008563.1 4696495 4696767 D acyltransferase 4696495..4696767 Escherichia coli APEC O1 4494574 YP_859736.1 CDS yjdK NC_008563.1 4696995 4697291 D hypothetical protein 4696995..4697291 Escherichia coli APEC O1 4494575 YP_859737.1 CDS lysS NC_008563.1 4697611 4699128 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4697611..4699128) Escherichia coli APEC O1 4494576 YP_859738.1 CDS yjdL NC_008563.1 4699365 4700822 R peptide transporter complement(4699365..4700822) Escherichia coli APEC O1 4494577 YP_859739.1 CDS cadA NC_008563.1 4700881 4703067 R lysine decarboxylase 1 complement(4700881..4703067) Escherichia coli APEC O1 4494578 YP_859740.1 CDS cadB NC_008563.1 4703108 4704442 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4703108..4704442) Escherichia coli APEC O1 4494579 YP_859741.1 CDS cadC NC_008563.1 4704808 4706346 R regulates the cadBA operon; CadC family transcriptional regulator complement(4704808..4706346) Escherichia coli APEC O1 4494580 YP_859742.1 CDS APECO1_2319 NC_008563.1 4707178 4707741 R hypothetical protein complement(4707178..4707741) Escherichia coli APEC O1 4494581 YP_859743.1 CDS APECO1_2318 NC_008563.1 4707826 4708248 R hypothetical protein complement(4707826..4708248) Escherichia coli APEC O1 4494582 YP_859744.1 CDS APECO1_2317 NC_008563.1 4708543 4709076 D hypothetical protein 4708543..4709076 Escherichia coli APEC O1 4494583 YP_859745.1 CDS yeeS3 NC_008563.1 4709467 4709943 R radC-like protein YeeS complement(4709467..4709943) Escherichia coli APEC O1 4494584 YP_859746.1 CDS APECO1_2315 NC_008563.1 4709994 4710401 D hypothetical protein 4709994..4710401 Escherichia coli APEC O1 4495030 YP_859747.1 CDS APECO1_2314 NC_008563.1 4710703 4711521 R hypothetical protein complement(4710703..4711521) Escherichia coli APEC O1 4495031 YP_859748.1 CDS APECO1_2313 NC_008563.1 4711850 4712635 R hypothetical protein complement(4711850..4712635) Escherichia coli APEC O1 4495032 YP_859749.1 CDS yfjR NC_008563.1 4712678 4713358 R transcriptional regulator complement(4712678..4713358) Escherichia coli APEC O1 4495033 YP_859750.1 CDS APECO1_2311 NC_008563.1 4713561 4714445 R GTPase complement(4713561..4714445) Escherichia coli APEC O1 4495034 YP_859751.1 CDS APECO1_2310 NC_008563.1 4714546 4715769 D hypothetical protein 4714546..4715769 Escherichia coli APEC O1 4495035 YP_859752.1 CDS APECO1_2309 NC_008563.1 4717222 4717953 D hypothetical protein 4717222..4717953 Escherichia coli APEC O1 4495036 YP_859753.1 CDS APECO1_2308 NC_008563.1 4718111 4718875 D hypothetical protein 4718111..4718875 Escherichia coli APEC O1 4495037 YP_859755.1 CDS APECO1_2306 NC_008563.1 4719452 4719787 R transposase InsC for insertion element IS2A/D/F/H/I/K complement(4719452..4719787) Escherichia coli APEC O1 4495039 YP_859756.1 CDS APECO1_2305 NC_008563.1 4719926 4720990 D cation/multidrug efflux pump protein 4719926..4720990 Escherichia coli APEC O1 4495040 YP_859757.1 CDS APECO1_2304 NC_008563.1 4721090 4721461 D transcriptional repressor 4721090..4721461 Escherichia coli APEC O1 4495041 YP_859758.1 CDS APECO1_2303 NC_008563.1 4722436 4723077 R hypothetical protein complement(4722436..4723077) Escherichia coli APEC O1 4495042 YP_859759.2 CDS APECO1_2302 NC_008563.1 4723026 4724177 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(4723026..4724177) Escherichia coli APEC O1 4495043 YP_859760.1 CDS APECO1_2301 NC_008563.1 4724306 4725361 R hypothetical protein complement(4724306..4725361) Escherichia coli APEC O1 4495044 YP_859761.1 CDS APECO1_2300 NC_008563.1 4725378 4726640 R histidine kinase complement(4725378..4726640) Escherichia coli APEC O1 4495045 YP_859762.1 CDS APECO1_2299 NC_008563.1 4726675 4726986 D hypothetical protein 4726675..4726986 Escherichia coli APEC O1 4495046 YP_859763.1 CDS APECO1_2298 NC_008563.1 4727190 4727711 R reverse trasncriptase-like protein; hypothetical protein complement(4727190..4727711) Escherichia coli APEC O1 4495047 YP_859764.1 CDS APECO1_2297 NC_008563.1 4727739 4728278 R reverse trasncriptase-like protein; hypothetical protein complement(4727739..4728278) Escherichia coli APEC O1 4495048 YP_859765.1 CDS APECO1_2296 NC_008563.1 4728503 4728790 D hypothetical protein 4728503..4728790 Escherichia coli APEC O1 4494251 YP_859766.1 CDS APECO1_2295 NC_008563.1 4728764 4729669 R hypothetical protein complement(4728764..4729669) Escherichia coli APEC O1 4494252 YP_859767.1 CDS APECO1_2294 NC_008563.1 4729806 4730723 R pyruvate-formate lyase-activating enzyme complement(4729806..4730723) Escherichia coli APEC O1 4494253 YP_859768.1 CDS APECO1_2293 NC_008563.1 4730832 4733384 R pyruvate formate-lyase complement(4730832..4733384) Escherichia coli APEC O1 4494254 YP_859769.1 CDS APECO1_2292 NC_008563.1 4733433 4734143 R peptidase complement(4733433..4734143) Escherichia coli APEC O1 4494255 YP_859770.1 CDS eutE NC_008563.1 4734342 4735868 R ethanolamine utilization protein EutE complement(4734342..4735868) Escherichia coli APEC O1 4494256 YP_859771.1 CDS eutL NC_008563.1 4735929 4736714 R propanediol utilization protein complement(4735929..4736714) Escherichia coli APEC O1 4494257 YP_859772.1 CDS pduA NC_008563.1 4736736 4737017 R propanediol utilization protein PduA complement(4736736..4737017) Escherichia coli APEC O1 4494258 YP_859773.1 CDS APECO1_2288 NC_008563.1 4737302 4738609 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(4737302..4738609) Escherichia coli APEC O1 4494259 YP_859774.1 CDS pduO NC_008563.1 4738527 4739024 R propanediol utilization protein complement(4738527..4739024) Escherichia coli APEC O1 4494260 YP_859775.1 CDS eutN NC_008563.1 4739052 4739321 R ethanolamine utilization protein EutN complement(4739052..4739321) Escherichia coli APEC O1 4494261 YP_859776.1 CDS APECO1_2285 NC_008563.1 4739333 4740058 R hypothetical protein complement(4739333..4740058) Escherichia coli APEC O1 4494262 YP_859777.1 CDS eutJ NC_008563.1 4740042 4740800 R ethanolamine utilization protein EutJ complement(4740042..4740800) Escherichia coli APEC O1 4494263 YP_859778.1 CDS APECO1_2283 NC_008563.1 4740855 4741541 R propanediol utilization protein complement(4740855..4741541) Escherichia coli APEC O1 4494264 YP_859779.1 CDS APECO1_2282 NC_008563.1 4741681 4742799 R iron-containing alcohol dehydrogenase complement(4741681..4742799) Escherichia coli APEC O1 4494265 YP_859780.1 CDS APECO1_2281 NC_008563.1 4743291 4743695 R hypothetical protein complement(4743291..4743695) Escherichia coli APEC O1 4494266 YP_859781.1 CDS APECO1_2280 NC_008563.1 4743929 4744204 D hypothetical protein 4743929..4744204 Escherichia coli APEC O1 4494267 YP_859782.1 CDS APECO1_2279 NC_008563.1 4744842 4745252 D hemolysin activator protein 4744842..4745252 Escherichia coli APEC O1 4494268 YP_859783.1 CDS APECO1_2278 NC_008563.1 4745339 4745722 D hypothetical protein 4745339..4745722 Escherichia coli APEC O1 4494269 YP_859784.1 CDS APECO1_2277 NC_008563.1 4745961 4747415 D hypothetical protein 4745961..4747415 Escherichia coli APEC O1 4494270 YP_859785.1 CDS APECO1_2276 NC_008563.1 4747547 4749331 D KAP family protein 4747547..4749331 Escherichia coli APEC O1 4492971 YP_859786.1 CDS APECO1_2275 NC_008563.1 4749331 4750083 D hypothetical protein 4749331..4750083 Escherichia coli APEC O1 4492972 YP_859787.1 CDS APECO1_2274 NC_008563.1 4750065 4751384 D hypothetical protein 4750065..4751384 Escherichia coli APEC O1 4492973 YP_859788.1 CDS APECO1_2273 NC_008563.1 4751381 4752106 D TatD-related deoxyribonuclease 4751381..4752106 Escherichia coli APEC O1 4492974 YP_859789.1 CDS APECO1_2272 NC_008563.1 4752659 4753234 R hypothetical protein complement(4752659..4753234) Escherichia coli APEC O1 4492975 YP_859790.1 CDS APECO1_2271 NC_008563.1 4753242 4754570 R hypothetical protein complement(4753242..4754570) Escherichia coli APEC O1 4492976 YP_859791.1 CDS APECO1_2270 NC_008563.1 4754911 4755723 R transposase insF for insertion sequence IS3A/B/C/D/E/fA complement(4754911..4755723) Escherichia coli APEC O1 4492977 YP_859792.1 CDS insN NC_008563.1 4755780 4756103 R transposase InsN for insertion sequence element IS911B complement(4755780..4756103) Escherichia coli APEC O1 4492978 YP_859793.1 CDS APECO1_2268 NC_008563.1 4756137 4756514 R hypothetical protein complement(4756137..4756514) Escherichia coli APEC O1 4492979 YP_859794.1 CDS insB NC_008563.1 4757137 4757496 R iso-InsB; IS1 InsB protein complement(4757137..4757496) Escherichia coli APEC O1 4492980 YP_859795.1 CDS insA NC_008563.1 4757523 4757795 R iso-InsA; IS1 InsA protein complement(4757523..4757795) Escherichia coli APEC O1 4492981 YP_859796.1 CDS APECO1_2265 NC_008563.1 4758048 4759517 D antiporter 4758048..4759517 Escherichia coli APEC O1 4492982 YP_859797.1 CDS APECO1_2264 NC_008563.1 4759622 4761991 D hypothetical protein 4759622..4761991 Escherichia coli APEC O1 4492983 YP_859798.1 CDS APECO1_2263 NC_008563.1 4762066 4763565 D amino acid antiporter 4762066..4763565 Escherichia coli APEC O1 4492984 YP_859799.1 CDS insA NC_008563.1 4763708 4763983 D IS1 InsA protein 4763708..4763983 Escherichia coli APEC O1 4492985 YP_859800.1 CDS insB NC_008563.1 4763902 4764405 D IS1 transposase; IS1 InsB protein 4763902..4764405 Escherichia coli APEC O1 4492986 YP_859801.1 CDS papX NC_008563.1 4764872 4765423 R regulator PapX protein complement(4764872..4765423) Escherichia coli APEC O1 4492987 YP_859802.1 CDS APECO1_2259 NC_008563.1 4765590 4765955 R integrase-like protein; hypothetical protein complement(4765590..4765955) Escherichia coli APEC O1 4492988 YP_859803.1 CDS APECO1_2258 NC_008563.1 4766031 4766357 R hypothetical protein complement(4766031..4766357) Escherichia coli APEC O1 4492989 YP_859804.1 CDS insB NC_008563.1 4766398 4766901 R IS1 transposase; IS1 InsB protein complement(4766398..4766901) Escherichia coli APEC O1 4491909 YP_859805.1 CDS insA NC_008563.1 4766820 4767095 R IS1 InsA protein complement(4766820..4767095) Escherichia coli APEC O1 4491910 YP_859806.1 CDS shiA NC_008563.1 4767625 4768698 R ShiA-like protein complement(4767625..4768698) Escherichia coli APEC O1 4491911 YP_859807.1 CDS int NC_008563.1 4768924 4770189 R Int ( P4-type integrase) complement(4768924..4770189) Escherichia coli APEC O1 4491912 YP_859808.1 CDS yjdC NC_008563.1 4770569 4771168 R transcriptional regulator complement(4770569..4771168) Escherichia coli APEC O1 4491913 YP_859809.1 CDS dipZ NC_008563.1 4771181 4772959 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4771181..4772959) Escherichia coli APEC O1 4491914 YP_859810.1 CDS dcuA NC_008563.1 4773308 4774609 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4773308..4774609) Escherichia coli APEC O1 4491915 YP_859811.1 CDS aspA NC_008563.1 4774727 4776208 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4774727..4776208) Escherichia coli APEC O1 4491916 YP_859812.1 CDS fxsA NC_008563.1 4776599 4776976 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4776599..4776976 Escherichia coli APEC O1 4491917 YP_859813.1 CDS yjeH NC_008563.1 4776992 4778308 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(4776992..4778308) Escherichia coli APEC O1 4491918 YP_859814.1 CDS APECO1_2247 NC_008563.1 4778391 4778714 R hypothetical protein complement(4778391..4778714) Escherichia coli APEC O1 4491919 YP_859815.1 CDS groEL NC_008563.1 4778861 4780507 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4778861..4780507 Escherichia coli APEC O1 4491920 YP_859816.1 CDS yjeI NC_008563.1 4780612 4780998 D hypothetical protein 4780612..4780998 Escherichia coli APEC O1 4495536 YP_859817.1 CDS yjeJ NC_008563.1 4781048 4781917 R hypothetical protein complement(4781048..4781917) Escherichia coli APEC O1 4495537 YP_859818.1 CDS yjeK NC_008563.1 4782152 4783180 R lysine aminomutase complement(4782152..4783180) Escherichia coli APEC O1 4495538 YP_859819.1 CDS efp NC_008563.1 4783222 4783788 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4783222..4783788 Escherichia coli APEC O1 4495539 YP_859820.1 CDS sugE NC_008563.1 4784398 4784715 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4784398..4784715 Escherichia coli APEC O1 4495540 YP_859821.1 CDS blc NC_008563.1 4784712 4785245 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4784712..4785245) Escherichia coli APEC O1 4495541 YP_859822.1 CDS ampC NC_008563.1 4785334 4786596 R beta-lactamase complement(4785334..4786596) Escherichia coli APEC O1 4495542 YP_859823.1 CDS frdD NC_008563.1 4786530 4786889 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4786530..4786889) Escherichia coli APEC O1 4495543 YP_859824.1 CDS frdC NC_008563.1 4786900 4787295 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4786900..4787295) Escherichia coli APEC O1 4495544 YP_859825.2 CDS frdB NC_008563.1 4787306 4788040 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4787306..4788040) Escherichia coli APEC O1 4495546 YP_859826.1 CDS frdA NC_008563.1 4788033 4789841 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4788033..4789841) Escherichia coli APEC O1 4495547 YP_859827.1 CDS yjeA NC_008563.1 4790136 4791143 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4790136..4791143 Escherichia coli APEC O1 4495548 YP_859828.1 CDS yjeM NC_008563.1 4791320 4792864 D transporter 4791320..4792864 Escherichia coli APEC O1 4495549 YP_859829.1 CDS yjeN NC_008563.1 4792927 4793241 D hypothetical protein 4792927..4793241 Escherichia coli APEC O1 4495550 YP_859830.1 CDS yjeO NC_008563.1 4793238 4793552 D hypothetical protein 4793238..4793552 Escherichia coli APEC O1 4495551 YP_859831.1 CDS yjeP NC_008563.1 4793583 4796906 R hypothetical protein complement(4793583..4796906) Escherichia coli APEC O1 4495552 YP_859832.1 CDS APECO1_2229 NC_008563.1 4796970 4797851 D hypothetical protein 4796970..4797851 Escherichia coli APEC O1 4495553 YP_859833.1 CDS yjeQ NC_008563.1 4797993 4799006 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4797993..4799006) Escherichia coli APEC O1 4495554 YP_859834.2 CDS orn NC_008563.1 4799140 4799685 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4799140..4799685 Escherichia coli APEC O1 4492122 YP_859836.1 CDS yjeS NC_008563.1 4800464 4801711 R electron transport protein YjeS complement(4800464..4801711) Escherichia coli APEC O1 4492124 YP_859837.1 CDS yjeF NC_008563.1 4801602 4803149 D hypothetical protein 4801602..4803149 Escherichia coli APEC O1 4492125 YP_859838.1 CDS yjeE NC_008563.1 4803121 4803582 D possibly involved in cell wall synthesis; ATPase 4803121..4803582 Escherichia coli APEC O1 4492126 YP_859839.1 CDS amiB NC_008563.1 4803601 4804938 D N-acetylmuramoyl-l-alanine amidase II 4803601..4804938 Escherichia coli APEC O1 4492127 YP_859840.1 CDS mutL NC_008563.1 4804948 4806795 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4804948..4806795 Escherichia coli APEC O1 4492128 YP_859841.1 CDS miaA NC_008563.1 4806788 4807738 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4806788..4807738 Escherichia coli APEC O1 4492129 YP_859842.1 CDS hfq NC_008563.1 4807824 4808132 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4807824..4808132 Escherichia coli APEC O1 4492130 YP_859843.1 CDS hflX NC_008563.1 4808277 4809488 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4808277..4809488 Escherichia coli APEC O1 4492131 YP_859844.1 CDS hflK NC_008563.1 4809574 4810833 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4809574..4810833 Escherichia coli APEC O1 4492132 YP_859845.1 CDS hflC NC_008563.1 4810836 4811840 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4810836..4811840 Escherichia coli APEC O1 4492133 YP_859846.1 CDS purA NC_008563.1 4812223 4813521 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4812223..4813521 Escherichia coli APEC O1 4492134 YP_859847.1 CDS yjeB NC_008563.1 4813726 4814151 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4813726..4814151 Escherichia coli APEC O1 4492135 YP_859848.1 CDS rnr NC_008563.1 4814148 4816631 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4814148..4816631 Escherichia coli APEC O1 4492136 YP_859849.1 CDS yjfH NC_008563.1 4816723 4817454 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4816723..4817454 Escherichia coli APEC O1 4492137 YP_859850.1 CDS yjfI NC_008563.1 4817581 4817982 D hypothetical protein 4817581..4817982 Escherichia coli APEC O1 4492138 YP_859851.1 CDS yjfJ NC_008563.1 4818001 4818699 D transcriptional regulator effector protein 4818001..4818699 Escherichia coli APEC O1 4492139 YP_859852.1 CDS yjfK NC_008563.1 4818749 4819408 D hypothetical protein 4818749..4819408 Escherichia coli APEC O1 4492140 YP_859853.1 CDS yjfL NC_008563.1 4819345 4819824 D hypothetical protein 4819345..4819824 Escherichia coli APEC O1 4492141 YP_859854.1 CDS yjfM NC_008563.1 4819834 4820472 D hypothetical protein 4819834..4820472 Escherichia coli APEC O1 4493587 YP_859855.1 CDS yjfC NC_008563.1 4820475 4821638 D synthetase/amidase 4820475..4821638 Escherichia coli APEC O1 4493588 YP_859856.1 CDS aidB NC_008563.1 4821707 4823347 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4821707..4823347 Escherichia coli APEC O1 4493589 YP_859857.1 CDS yjfN NC_008563.1 4823464 4823766 R hypothetical protein complement(4823464..4823766) Escherichia coli APEC O1 4493590 YP_859858.1 CDS APECO1_2203 NC_008563.1 4823888 4824316 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(4823888..4824316) Escherichia coli APEC O1 4493591 YP_859859.1 CDS APECO1_2202 NC_008563.1 4824399 4825148 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4824399..4825148 Escherichia coli APEC O1 4493592 YP_859860.1 CDS yjfQ NC_008563.1 4825145 4825900 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4825145..4825900) Escherichia coli APEC O1 4493593 YP_859861.1 CDS ulaG NC_008563.1 4826008 4827078 R L-ascorbate 6-phosphate lactonase complement(4826008..4827078) Escherichia coli APEC O1 4493594 YP_859862.2 CDS ulaA NC_008563.1 4827427 4828824 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4827427..4828824 Escherichia coli APEC O1 4493595 YP_859864.1 CDS APECO1_2197 NC_008563.1 4829161 4829493 R hypothetical protein complement(4829161..4829493) Escherichia coli APEC O1 4493597 YP_859865.2 CDS ulaD NC_008563.1 4829633 4830283 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4829633..4830283 Escherichia coli APEC O1 4493598 YP_859866.1 CDS ulaE NC_008563.1 4830293 4831147 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4830293..4831147 Escherichia coli APEC O1 4493599 YP_859867.1 CDS sgaE NC_008563.1 4831147 4831833 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4831147..4831833 Escherichia coli APEC O1 4493600 YP_859868.1 CDS yjfY NC_008563.1 4831962 4832237 R hypothetical protein complement(4831962..4832237) Escherichia coli APEC O1 4493601 YP_859869.1 CDS rpsF NC_008563.1 4832565 4832960 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4832565..4832960 Escherichia coli APEC O1 4493602 YP_859870.1 CDS priB NC_008563.1 4832967 4833281 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4832967..4833281 Escherichia coli APEC O1 4493603 YP_859871.1 CDS rplI NC_008563.1 4833555 4834004 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4833555..4834004 Escherichia coli APEC O1 4493604 YP_859872.1 CDS APECO1_2189 NC_008563.1 4834406 4834897 D hypothetical protein 4834406..4834897 Escherichia coli APEC O1 4493605 YP_859873.1 CDS APECO1_2188 NC_008563.1 4834900 4836168 D hypothetical protein 4834900..4836168 Escherichia coli APEC O1 4495230 YP_859874.1 CDS APECO1_2187 NC_008563.1 4836311 4837588 R hexuronate transporter complement(4836311..4837588) Escherichia coli APEC O1 4495231 YP_859875.1 CDS APECO1_2186 NC_008563.1 4837681 4839753 R oxidoreductase complement(4837681..4839753) Escherichia coli APEC O1 4495232 YP_859876.1 CDS APECO1_2185 NC_008563.1 4839750 4841291 R acetyl-CoA:acetoacetyl-CoA transferase complement(4839750..4841291) Escherichia coli APEC O1 4495233 YP_859877.1 CDS APECO1_2184 NC_008563.1 4841301 4842077 R hypothetical protein complement(4841301..4842077) Escherichia coli APEC O1 4495235 YP_859878.1 CDS APECO1_2183 NC_008563.1 4842080 4842928 R hypothetical protein complement(4842080..4842928) Escherichia coli APEC O1 4495236 YP_859879.2 CDS APECO1_2182 NC_008563.1 4842938 4843729 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(4842938..4843729) Escherichia coli APEC O1 4495237 YP_859880.1 CDS APECO1_2181 NC_008563.1 4843905 4844588 D transcriptional regulator 4843905..4844588 Escherichia coli APEC O1 4495238 YP_859881.1 CDS ytfB NC_008563.1 4844572 4845246 R cell envelope opacity-associated protein complement(4844572..4845246) Escherichia coli APEC O1 4495239 YP_859882.1 CDS fklB NC_008563.1 4845269 4846048 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4845269..4846048 Escherichia coli APEC O1 4495240 YP_859883.1 CDS cycA NC_008563.1 4846357 4847769 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4846357..4847769 Escherichia coli APEC O1 4495241 YP_859884.1 CDS ytfE NC_008563.1 4847814 4848476 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4847814..4848476) Escherichia coli APEC O1 4495242 YP_859885.1 CDS ytfF NC_008563.1 4848584 4849558 R hypothetical protein complement(4848584..4849558) Escherichia coli APEC O1 4495244 YP_859886.1 CDS ytfG NC_008563.1 4849657 4850517 R hypothetical protein complement(4849657..4850517) Escherichia coli APEC O1 4495245 YP_859887.1 CDS ytfH NC_008563.1 4850495 4850986 D hypothetical protein 4850495..4850986 Escherichia coli APEC O1 4495246 YP_859888.1 CDS cpdB NC_008563.1 4851115 4853067 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4851115..4853067) Escherichia coli APEC O1 4495247 YP_859889.1 CDS cysQ NC_008563.1 4853248 4853988 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4853248..4853988 Escherichia coli APEC O1 4493048 YP_859890.1 CDS ytfJ NC_008563.1 4853978 4854535 R hypothetical protein complement(4853978..4854535) Escherichia coli APEC O1 4493049 YP_859891.1 CDS ytfL NC_008563.1 4855144 4856487 R transporter complement(4855144..4856487) Escherichia coli APEC O1 4493050 YP_859892.1 CDS msrA NC_008563.1 4856810 4857475 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4856810..4857475) Escherichia coli APEC O1 4493051 YP_859893.1 CDS ytfM NC_008563.1 4857654 4859387 D outer membrane protein 4857654..4859387 Escherichia coli APEC O1 4493052 YP_859894.1 CDS ytfN NC_008563.1 4859384 4863163 D hypothetical protein 4859384..4863163 Escherichia coli APEC O1 4493053 YP_859895.1 CDS APECO1_2166 NC_008563.1 4863166 4863507 D hypothetical protein 4863166..4863507 Escherichia coli APEC O1 4493054 YP_859896.1 CDS ppa NC_008563.1 4863887 4864417 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4863887..4864417) Escherichia coli APEC O1 4493055 YP_859897.1 CDS ytfQ NC_008563.1 4864727 4865683 D ABC transporter substrate-binding protein 4864727..4865683 Escherichia coli APEC O1 4493056 YP_859898.1 CDS ytfR NC_008563.1 4865823 4867325 D ATP-binding component of a transport system 4865823..4867325 Escherichia coli APEC O1 4493057 YP_859899.1 CDS ytfT NC_008563.1 4867336 4868361 D ABC transporter permease 4867336..4868361 Escherichia coli APEC O1 4493058 YP_859900.1 CDS yjfF NC_008563.1 4868348 4869343 D membrane component of a sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4868348..4869343 Escherichia coli APEC O1 4493059 YP_859901.1 CDS fbp NC_008563.1 4869376 4870374 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4869376..4870374) Escherichia coli APEC O1 4493060 YP_859902.1 CDS mpl NC_008563.1 4870550 4871923 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4870550..4871923 Escherichia coli APEC O1 4493061 YP_859903.1 CDS yjgA NC_008563.1 4872081 4872632 R hypothetical protein complement(4872081..4872632) Escherichia coli APEC O1 4493062 YP_859904.1 CDS pmbA NC_008563.1 4872726 4874078 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4872726..4874078 Escherichia coli APEC O1 4493063 YP_859905.1 CDS cybC NC_008563.1 4874262 4874648 D soluble cytochrome b562 4874262..4874648 Escherichia coli APEC O1 4493064 YP_859906.1 CDS nrdG NC_008563.1 4874693 4875157 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4874693..4875157) Escherichia coli APEC O1 4493065 YP_859907.1 CDS nrdD NC_008563.1 4875315 4877453 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4875315..4877453) Escherichia coli APEC O1 4493066 YP_859908.1 CDS treC NC_008563.1 4877847 4879502 R trehalose-6-phosphate hydrolase complement(4877847..4879502) Escherichia coli APEC O1 4494061 YP_859909.1 CDS treB NC_008563.1 4879552 4880973 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(4879552..4880973) Escherichia coli APEC O1 4494062 YP_859910.1 CDS treR NC_008563.1 4881092 4882039 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4881092..4882039) Escherichia coli APEC O1 4494063 YP_859911.1 CDS mgtA NC_008563.1 4882418 4885114 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4882418..4885114 Escherichia coli APEC O1 4494064 YP_859912.1 CDS yjgF NC_008563.1 4885320 4885745 R hypothetical protein complement(4885320..4885745) Escherichia coli APEC O1 4494065 YP_859913.1 CDS pyrI NC_008563.1 4885779 4886240 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit complement(4885779..4886240) Escherichia coli APEC O1 4494066 YP_859914.1 CDS pyrB NC_008563.1 4886253 4887188 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(4886253..4887188) Escherichia coli APEC O1 4494067 YP_859915.1 CDS APECO1_2146 NC_008563.1 4887416 4887970 R arganine repressor complement(4887416..4887970) Escherichia coli APEC O1 4494068 YP_859916.1 CDS APECO1_2145 NC_008563.1 4888020 4888973 R hypothetical protein complement(4888020..4888973) Escherichia coli APEC O1 4494069 YP_859917.1 CDS argF NC_008563.1 4889480 4890484 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(4889480..4890484) Escherichia coli APEC O1 4494070 YP_859918.2 CDS APECO1_2143 NC_008563.1 4890495 4891439 R reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4890495..4891439) Escherichia coli APEC O1 4494071 YP_859919.1 CDS APECO1_2142 NC_008563.1 4891450 4892673 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(4891450..4892673) Escherichia coli APEC O1 4494072 YP_859920.1 CDS yjgK NC_008563.1 4893348 4893800 D hypothetical protein 4893348..4893800 Escherichia coli APEC O1 4494073 YP_859921.1 CDS argI NC_008563.1 4893846 4895054 R ornithine carbamoyltransferase 1 complement(4893846..4895054) Escherichia coli APEC O1 4494074 YP_859922.1 CDS yjgD NC_008563.1 4895012 4895428 D hypothetical protein 4895012..4895428 Escherichia coli APEC O1 4494075 YP_859923.1 CDS yjgM NC_008563.1 4895605 4896108 R acetyltransferase YjgM complement(4895605..4896108) Escherichia coli APEC O1 4494076 YP_859924.1 CDS yjgN NC_008563.1 4896301 4897488 D hypothetical protein 4896301..4897488 Escherichia coli APEC O1 4494077 YP_859925.1 CDS valS NC_008563.1 4897535 4900390 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4897535..4900390) Escherichia coli APEC O1 4494078 YP_859926.1 CDS holC NC_008563.1 4900390 4900833 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4900390..4900833) Escherichia coli APEC O1 4494079 YP_859927.1 CDS pepA NC_008563.1 4901091 4902602 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4901091..4902602) Escherichia coli APEC O1 4494080 YP_859928.1 CDS APECO1_2133 NC_008563.1 4902869 4903969 D hypothetical protein 4902869..4903969 Escherichia coli APEC O1 4493908 YP_859929.1 CDS yjgQ NC_008563.1 4903966 4905051 D hypothetical protein 4903966..4905051 Escherichia coli APEC O1 4493909 YP_859930.1 CDS yjgR NC_008563.1 4905186 4906715 R hypothetical protein complement(4905186..4906715) Escherichia coli APEC O1 4493910 YP_859931.1 CDS idnR NC_008563.1 4906793 4907791 R L-idonate regulatory protein complement(4906793..4907791) Escherichia coli APEC O1 4493911 YP_859932.1 CDS idnT NC_008563.1 4907858 4909177 R L-idonate and D-gluconate transporter complement(4907858..4909177) Escherichia coli APEC O1 4493912 YP_859933.1 CDS idnO NC_008563.1 4909242 4910006 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(4909242..4910006) Escherichia coli APEC O1 4493913 YP_859934.1 CDS idnD NC_008563.1 4910030 4911061 R NAD-binding; L-idonate 5-dehydrogenase complement(4910030..4911061) Escherichia coli APEC O1 4493914 YP_859935.1 CDS idnK NC_008563.1 4911278 4911841 D D-gluconate kinase 4911278..4911841 Escherichia coli APEC O1 4493915 YP_859936.1 CDS yjgB NC_008563.1 4911845 4912906 R oxidoreductase complement(4911845..4912906) Escherichia coli APEC O1 4493916 YP_859937.1 CDS APECO1_2124 NC_008563.1 4913953 4915869 D hypothetical protein 4913953..4915869 Escherichia coli APEC O1 4493917 YP_859938.1 CDS APECO1_2123 NC_008563.1 4916492 4917397 R hypothetical protein complement(4916492..4917397) Escherichia coli APEC O1 4493918 YP_859939.1 CDS yjhS NC_008563.1 4917576 4918556 R hypothetical protein complement(4917576..4918556) Escherichia coli APEC O1 4493919 YP_859940.1 CDS yjhT NC_008563.1 4918621 4919835 R N-acetylneuraminic acid mutarotase complement(4918621..4919835) Escherichia coli APEC O1 4493920 YP_859941.1 CDS yjhA NC_008563.1 4919747 4920472 R hypothetical protein complement(4919747..4920472) Escherichia coli APEC O1 4493921 YP_859942.1 CDS APECO1_2119 NC_008563.1 4921262 4921669 R hypothetical protein complement(4921262..4921669) Escherichia coli APEC O1 4493922 YP_859943.1 CDS fimB NC_008563.1 4921929 4922531 D inversion of on/off regulator of fimA; tyrosine recombinase 4921929..4922531 Escherichia coli APEC O1 4493923 YP_859944.1 CDS fimE NC_008563.1 4923009 4923605 D inversion of on/off regulator of fimA; tyrosine recombinase 4923009..4923605 Escherichia coli APEC O1 4493924 YP_859945.1 CDS fimA NC_008563.1 4924029 4924640 D type 1 fimbriae major subunit FimA 4924029..4924640 Escherichia coli APEC O1 4493925 YP_859946.1 CDS fimI NC_008563.1 4924582 4925244 D FimI fimbrial protein 4924582..4925244 Escherichia coli APEC O1 4493926 YP_859947.1 CDS fimC NC_008563.1 4925281 4926006 D type I fimbrial chaperone 4925281..4926006 Escherichia coli APEC O1 4492142 YP_859948.1 CDS fimD NC_008563.1 4926072 4928708 D outer membrane usher protein FimD 4926072..4928708 Escherichia coli APEC O1 4492143 YP_859949.1 CDS APECO1_2112 NC_008563.1 4928715 4929248 D FimF protein 4928715..4929248 Escherichia coli APEC O1 4492144 YP_859950.1 CDS fimA NC_008563.1 4929255 4929764 D P pilus assembly protein, pilin FimA 4929255..4929764 Escherichia coli APEC O1 4492145 YP_859951.1 CDS fimH NC_008563.1 4929775 4930686 D type 1 fimbiral adhesin FimH 4929775..4930686 Escherichia coli APEC O1 4492146 YP_859952.1 CDS uxuA NC_008563.1 4931415 4932599 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4931415..4932599 Escherichia coli APEC O1 4492147 YP_859953.1 CDS uxuB NC_008563.1 4932680 4934140 D D-mannonate oxidoreductase 4932680..4934140 Escherichia coli APEC O1 4492148 YP_859954.1 CDS uxuR NC_008563.1 4934355 4935128 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4934355..4935128 Escherichia coli APEC O1 4492149 YP_859955.1 CDS iraD NC_008563.1 4935533 4935925 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4935533..4935925 Escherichia coli APEC O1 4492150 YP_859956.1 CDS pptE NC_008563.1 4935973 4938354 R phosphoenolpyruvate-protein phosphoryltransferase PptE complement(4935973..4938354) Escherichia coli APEC O1 4492151 YP_859957.1 CDS ptnK NC_008563.1 4938358 4938990 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(4938358..4938990) Escherichia coli APEC O1 4492152 YP_859958.1 CDS ptnC NC_008563.1 4939003 4940073 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(4939003..4940073) Escherichia coli APEC O1 4492153 YP_859959.1 CDS gldA NC_008563.1 4940392 4941474 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4940392..4941474 Escherichia coli APEC O1 4492154 YP_859960.1 CDS APECO1_2101 NC_008563.1 4941541 4942809 D transporter 4941541..4942809 Escherichia coli APEC O1 4492155 YP_859961.1 CDS APECO1_2100 NC_008563.1 4942827 4944191 D dihydrolipoamide dehydrogenase 4942827..4944191 Escherichia coli APEC O1 4492156 YP_859962.1 CDS cniT NC_008563.1 4944492 4946033 D carnitine transporter CniT 4944492..4946033 Escherichia coli APEC O1 4492157 YP_859963.1 CDS gclK NC_008563.1 4946089 4947231 R glycerate kinase complement(4946089..4947231) Escherichia coli APEC O1 4492158 YP_859964.1 CDS ghbD NC_008563.1 4947306 4948193 R 3-hydroxyisobutyrate dehydrogenase complement(4947306..4948193) Escherichia coli APEC O1 4492159 YP_859965.1 CDS gclR NC_008563.1 4948211 4948993 R regulatory protein GclR complement(4948211..4948993) Escherichia coli APEC O1 4492160 YP_859966.1 CDS gclA NC_008563.1 4949006 4950745 R catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase complement(4949006..4950745) Escherichia coli APEC O1 4492161 YP_859967.1 CDS ibeR NC_008563.1 4951124 4953073 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 4951124..4953073 Escherichia coli APEC O1 4493340 YP_859968.1 CDS ibeA NC_008563.1 4953360 4954730 D invasion protein IbeA 4953360..4954730 Escherichia coli APEC O1 4493341 YP_859969.1 CDS ibeT NC_008563.1 4954745 4956148 D transporter IbeT 4954745..4956148 Escherichia coli APEC O1 4493342 YP_859970.1 CDS yjiE NC_008563.1 4956235 4956963 R DNA-binding transcriptional regulator complement(4956235..4956963) Escherichia coli APEC O1 4493343 YP_859971.1 CDS iadA NC_008563.1 4957211 4958383 R isoaspartyl dipeptidase complement(4957211..4958383) Escherichia coli APEC O1 4493344 YP_859972.1 CDS yjiG NC_008563.1 4958396 4958857 R hypothetical protein complement(4958396..4958857) Escherichia coli APEC O1 4493345 YP_859973.1 CDS yjiH NC_008563.1 4958854 4959549 R hypothetical protein complement(4958854..4959549) Escherichia coli APEC O1 4493346 YP_859974.1 CDS yjiI NC_008563.1 4959685 4960146 D in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4959685..4960146 Escherichia coli APEC O1 4493347 YP_859975.1 CDS yjiJ NC_008563.1 4960353 4961531 R permease complement(4960353..4961531) Escherichia coli APEC O1 4493348 YP_859976.1 CDS yjiK NC_008563.1 4961599 4962570 R hypothetical protein complement(4961599..4962570) Escherichia coli APEC O1 4493349 YP_859977.1 CDS yjiL NC_008563.1 4962778 4963551 R ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase complement(4962778..4963551) Escherichia coli APEC O1 4493350 YP_859978.1 CDS yjiM NC_008563.1 4963555 4964727 R 2-hydroxyglutaryl-CoA dehydratase complement(4963555..4964727) Escherichia coli APEC O1 4493351 YP_859979.1 CDS yjiN NC_008563.1 4964822 4966102 R hypothetical protein complement(4964822..4966102) Escherichia coli APEC O1 4493352 YP_859980.1 CDS yjiP NC_008563.1 4966287 4967207 D hypothetical protein 4966287..4967207 Escherichia coli APEC O1 4493353 YP_859981.1 CDS APECO1_2080 NC_008563.1 4967505 4969706 D hypothetical protein 4967505..4969706 Escherichia coli APEC O1 4493354 YP_859982.1 CDS yjiW NC_008563.1 4969753 4970151 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(4969753..4970151) Escherichia coli APEC O1 4493355 YP_859983.1 CDS hsdS NC_008563.1 4970323 4971690 R specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS complement(4970323..4971690) Escherichia coli APEC O1 4493356 YP_859984.1 CDS hsdM NC_008563.1 4971687 4973276 R DNA methylase M complement(4971687..4973276) Escherichia coli APEC O1 4493357 YP_859985.1 CDS hsdR NC_008563.1 4973478 4976990 R restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R complement(4973478..4976990) Escherichia coli APEC O1 4493358 YP_859986.1 CDS mrr NC_008563.1 4977178 4978092 D methylated adenine and cytosine restriction protein 4977178..4978092 Escherichia coli APEC O1 4494932 YP_859987.1 CDS yjiA NC_008563.1 4978138 4979178 R GTP-binding protein YjiA complement(4978138..4979178) Escherichia coli APEC O1 4494933 YP_859988.1 CDS yjiY NC_008563.1 4979426 4981591 R carbon starvation protein complement(4979426..4981591) Escherichia coli APEC O1 4494934 YP_859989.1 CDS tsr NC_008563.1 4981953 4983608 D methyl-accepting chemotaxis protein I, serine sensor receptor 4981953..4983608 Escherichia coli APEC O1 4494935 YP_859990.1 CDS APECO1_2071 NC_008563.1 4983651 4984922 R C4-dicarboxylate transport system permease large protein complement(4983651..4984922) Escherichia coli APEC O1 4494936 YP_859991.1 CDS APECO1_2070 NC_008563.1 4984919 4985392 R C4-dicarboxylate transport system permease small protein complement(4984919..4985392) Escherichia coli APEC O1 4494937 YP_859992.1 CDS APECO1_2069 NC_008563.1 4985456 4986427 R C4-dicarboxylate-binding protein complement(4985456..4986427) Escherichia coli APEC O1 4494938 YP_859993.1 CDS yjcE NC_008563.1 4987097 4988770 D Na(+)/H(+) exchanger YjcE 4987097..4988770 Escherichia coli APEC O1 4494939 YP_859994.1 CDS yjjM NC_008563.1 4988941 4989846 R DNA-binding transcriptional regulator complement(4988941..4989846) Escherichia coli APEC O1 4494940 YP_859995.1 CDS yjjN NC_008563.1 4989985 4991007 D oxidoreductase, Zn-dependent and NAD(P)-binding 4989985..4991007 Escherichia coli APEC O1 4494941 YP_859996.1 CDS mdoB NC_008563.1 4991147 4993399 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4991147..4993399) Escherichia coli APEC O1 4494942 YP_859997.1 CDS yjjA NC_008563.1 4993692 4994189 R hypothetical protein complement(4993692..4994189) Escherichia coli APEC O1 4494943 YP_859998.1 CDS dnaC NC_008563.1 4994235 4994972 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4994235..4994972) Escherichia coli APEC O1 4494944 YP_859999.1 CDS dnaT NC_008563.1 4994975 4995514 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4994975..4995514) Escherichia coli APEC O1 4494945 YP_860000.1 CDS yjjB NC_008563.1 4995622 4996095 R hypothetical protein complement(4995622..4996095) Escherichia coli APEC O1 4494946 YP_860001.1 CDS yjjP NC_008563.1 4996086 4996919 R hypothetical protein complement(4996086..4996919) Escherichia coli APEC O1 4494947 YP_860002.1 CDS yjjQ NC_008563.1 4997476 4998201 D global regulator; hypothetical protein 4997476..4998201 Escherichia coli APEC O1 4494948 YP_860003.1 CDS bglJ NC_008563.1 4998159 4998836 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; BglJ family transcriptional regulator 4998159..4998836 Escherichia coli APEC O1 4494949 YP_860004.1 CDS fhuF NC_008563.1 4998874 4999662 R ferric hydroximate transport ferric iron reductase complement(4998874..4999662) Escherichia coli APEC O1 4494950 YP_860005.1 CDS APECO1_2056 NC_008563.1 4999764 5000039 D hypothetical protein 4999764..5000039 Escherichia coli APEC O1 4494951 YP_860006.1 CDS rsmC NC_008563.1 5000601 5001632 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(5000601..5001632) Escherichia coli APEC O1 4495367 YP_860008.1 CDS rimI NC_008563.1 5002117 5002563 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5002117..5002563 Escherichia coli APEC O1 4495369 YP_860009.1 CDS yjjG NC_008563.1 5002578 5003255 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5002578..5003255 Escherichia coli APEC O1 4495370 YP_860010.1 CDS APECO1_2052 NC_008563.1 5003641 5004855 D hypothetical protein 5003641..5004855 Escherichia coli APEC O1 4495371 YP_860011.1 CDS APECO1_2051 NC_008563.1 5005231 5006226 R hypothetical protein complement(5005231..5006226) Escherichia coli APEC O1 4495372 YP_860012.1 CDS APECO1_2050 NC_008563.1 5006794 5007414 R hypothetical protein complement(5006794..5007414) Escherichia coli APEC O1 4495373 YP_860013.1 CDS APECO1_2049 NC_008563.1 5007414 5007776 R hypothetical protein complement(5007414..5007776) Escherichia coli APEC O1 4495374 YP_860014.1 CDS yfdR NC_008563.1 5007767 5008333 R hypothetical protein complement(5007767..5008333) Escherichia coli APEC O1 4495375 YP_860015.1 CDS yfdQ NC_008563.1 5008431 5009255 R hypothetical protein complement(5008431..5009255) Escherichia coli APEC O1 4495376 YP_860016.1 CDS APECO1_2046 NC_008563.1 5009321 5009701 R hypothetical protein complement(5009321..5009701) Escherichia coli APEC O1 4495377 YP_860017.1 CDS APECO1_2045 NC_008563.1 5010406 5011098 R regulatory protein complement(5010406..5011098) Escherichia coli APEC O1 4495378 YP_860018.1 CDS APECO1_2044 NC_008563.1 5011196 5011456 D hypothetical protein 5011196..5011456 Escherichia coli APEC O1 4495379 YP_860019.1 CDS APECO1_2043 NC_008563.1 5011449 5012000 D hypothetical protein 5011449..5012000 Escherichia coli APEC O1 4495380 YP_860020.1 CDS APECO1_2042 NC_008563.1 5011997 5013148 D phage-related; antirepressor 5011997..5013148 Escherichia coli APEC O1 4495381 YP_860021.1 CDS APECO1_2041 NC_008563.1 5013366 5014184 D phage-related; replication protein 5013366..5014184 Escherichia coli APEC O1 4495382 YP_860022.1 CDS yfdN NC_008563.1 5014187 5014675 D phage-related; hypothetical protein 5014187..5014675 Escherichia coli APEC O1 4495383 YP_860023.1 CDS APECO1_2039 NC_008563.1 5014642 5015001 D phage-related; hypothetical protein 5014642..5015001 Escherichia coli APEC O1 4495384 YP_860024.1 CDS APECO1_2038 NC_008563.1 5014998 5015387 D Holliday junction resolvase; bacteriophage V crossover junction endodeoxyribonuclease 5014998..5015387 Escherichia coli APEC O1 4495385 YP_860025.1 CDS APECO1_2037 NC_008563.1 5015407 5015895 D hypothetical protein 5015407..5015895 Escherichia coli APEC O1 4495135 YP_860026.1 CDS ydfA NC_008563.1 5016207 5017202 D hypothetical protein 5016207..5017202 Escherichia coli APEC O1 4495136 YP_860027.1 CDS APECO1_2035 NC_008563.1 5017174 5017968 D lambdoid prophage Qin antitermination protein Q-like protein 5017174..5017968 Escherichia coli APEC O1 4495137 YP_860028.1 CDS APECO1_2034 NC_008563.1 5020085 5020636 D hypothetical protein 5020085..5020636 Escherichia coli APEC O1 4495138 YP_860029.1 CDS ydfQ NC_008563.1 5020958 5021491 D Qin prophage; lysozyme 5020958..5021491 Escherichia coli APEC O1 4495139 YP_860030.1 CDS ydfP NC_008563.1 5021488 5021985 D hypothetical protein 5021488..5021985 Escherichia coli APEC O1 4495140 YP_860031.1 CDS APECO1_2031 NC_008563.1 5022794 5023063 D hypothetical protein 5022794..5023063 Escherichia coli APEC O1 4495141 YP_860032.1 CDS APECO1_2030 NC_008563.1 5024196 5024474 D hypothetical protein 5024196..5024474 Escherichia coli APEC O1 4495142 YP_860033.1 CDS APECO1_2029 NC_008563.1 5024464 5024955 D phage-related; hypothetical protein 5024464..5024955 Escherichia coli APEC O1 4495143 YP_860034.1 CDS APECO1_2028 NC_008563.1 5024955 5027057 D DNA packaging protein of prophage CP-933K 5024955..5027057 Escherichia coli APEC O1 4495144 YP_860035.1 CDS APECO1_2027 NC_008563.1 5027194 5028774 D capsid protein 5027194..5028774 Escherichia coli APEC O1 4495145 YP_860036.1 CDS APECO1_2026 NC_008563.1 5028569 5030746 D protease/scaffold protein 5028569..5030746 Escherichia coli APEC O1 4495146 YP_860037.1 CDS APECO1_2025 NC_008563.1 5030833 5031156 D hypothetical protein 5030833..5031156 Escherichia coli APEC O1 4495147 YP_860038.1 CDS APECO1_2024 NC_008563.1 5031149 5031424 D phage-related; hypothetical protein 5031149..5031424 Escherichia coli APEC O1 4495148 YP_860039.1 CDS APECO1_2023 NC_008563.1 5031436 5032014 D tail component of prophage CP-933K 5031436..5032014 Escherichia coli APEC O1 4495149 YP_860040.1 CDS APECO1_2022 NC_008563.1 5032348 5033166 D tail component of prophage CP-933K 5032348..5033166 Escherichia coli APEC O1 4495150 YP_860041.1 CDS APECO1_2021 NC_008563.1 5033215 5033613 D tail component of prophage CP-933K 5033215..5033613 Escherichia coli APEC O1 4495151 YP_860042.1 CDS APECO1_2020 NC_008563.1 5033622 5033951 D minor tail protein 5033622..5033951 Escherichia coli APEC O1 4495152 YP_860043.1 CDS APECO1_2019 NC_008563.1 5033914 5036988 D tail component of prophage CP-933K 5033914..5036988 Escherichia coli APEC O1 4495153 YP_860044.1 CDS APECO1_2018 NC_008563.1 5036988 5037317 D minor tail protein 5036988..5037317 Escherichia coli APEC O1 4495154 YP_860045.1 CDS APECO1_2017 NC_008563.1 5037327 5038025 D minor tail protein 5037327..5038025 Escherichia coli APEC O1 4491959 YP_860046.1 CDS APECO1_2016 NC_008563.1 5038030 5038773 D tail fiber component K of prophage 5038030..5038773 Escherichia coli APEC O1 4491960 YP_860047.1 CDS APECO1_2015 NC_008563.1 5038671 5039318 D phage-related; tail component of prophage CP-933K 5038671..5039318 Escherichia coli APEC O1 4491961 YP_860048.1 CDS APECO1_2014 NC_008563.1 5039379 5042774 D phage-related; tail component of prophage 5039379..5042774 Escherichia coli APEC O1 4491962 YP_860049.1 CDS APECO1_2013 NC_008563.1 5042842 5043441 D outer membrane protein 5042842..5043441 Escherichia coli APEC O1 4491963 YP_860050.1 CDS APECO1_2012 NC_008563.1 5043500 5045884 D phage-related; hypothetical protein 5043500..5045884 Escherichia coli APEC O1 4491964 YP_860051.1 CDS APECO1_2011 NC_008563.1 5045884 5046165 D hypothetical protein 5045884..5046165 Escherichia coli APEC O1 4491965 YP_860052.1 CDS APECO1_2010 NC_008563.1 5046175 5046879 D hypothetical protein 5046175..5046879 Escherichia coli APEC O1 4491966 YP_860053.1 CDS APECO1_2009 NC_008563.1 5046970 5047323 R hypothetical protein complement(5046970..5047323) Escherichia coli APEC O1 4491967 YP_860054.1 CDS pinR NC_008563.1 5047411 5048001 R recombinase; Rac prophage; site-specific recombinase complement(5047411..5048001) Escherichia coli APEC O1 4491968 YP_860055.1 CDS ydfK NC_008563.1 5048318 5048584 R hypothetical protein complement(5048318..5048584) Escherichia coli APEC O1 4491969 YP_860056.1 CDS prfC NC_008563.1 5049628 5051214 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5049628..5051214 Escherichia coli APEC O1 4491970 YP_860057.1 CDS APECO1_2005 NC_008563.1 5051607 5052212 D hypothetical protein 5051607..5052212 Escherichia coli APEC O1 4491971 YP_860058.1 CDS yjjU NC_008563.1 5052622 5053695 D hypothetical protein 5052622..5053695 Escherichia coli APEC O1 4491972 YP_860059.1 CDS yjjV NC_008563.1 5053836 5054471 D deoxyribonuclease YjjV 5053836..5054471 Escherichia coli APEC O1 4491973 YP_860060.1 CDS APECO1_2002 NC_008563.1 5054688 5055551 R hypothetical protein complement(5054688..5055551) Escherichia coli APEC O1 4491974 YP_860061.1 CDS yjjI NC_008563.1 5055523 5057073 R hypothetical protein complement(5055523..5057073) Escherichia coli APEC O1 4491975 YP_860062.1 CDS deoC NC_008563.1 5057331 5058110 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5057331..5058110 Escherichia coli APEC O1 4491976 YP_860063.1 CDS deoA NC_008563.1 5058137 5059510 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5058137..5059510 Escherichia coli APEC O1 4491977 YP_860064.1 CDS deoB NC_008563.1 5059562 5060785 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5059562..5060785 Escherichia coli APEC O1 4494736 YP_860065.1 CDS deoD NC_008563.1 5060785 5061561 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5060785..5061561 Escherichia coli APEC O1 4494737 YP_860066.1 CDS yjjJ NC_008563.1 5061728 5063059 D hypothetical protein 5061728..5063059 Escherichia coli APEC O1 4494738 YP_860067.1 CDS lplA NC_008563.1 5063060 5064076 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(5063060..5064076) Escherichia coli APEC O1 4494739 YP_860068.1 CDS smp NC_008563.1 5064104 5064748 R hypothetical protein complement(5064104..5064748) Escherichia coli APEC O1 4494740 YP_860069.2 CDS serB NC_008563.1 5064854 5065822 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5064854..5065822 Escherichia coli APEC O1 4494741 YP_860070.1 CDS radA NC_008563.1 5065871 5067253 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5065871..5067253 Escherichia coli APEC O1 4494742 YP_860071.1 CDS nadR NC_008563.1 5067253 5068506 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5067253..5068506 Escherichia coli APEC O1 4494743 YP_860072.1 CDS APECO1_1990 NC_008563.1 5068520 5068930 D hypothetical protein 5068520..5068930 Escherichia coli APEC O1 4494744 YP_860073.1 CDS APECO1_1989 NC_008563.1 5068932 5069216 D regulatory protein 5068932..5069216 Escherichia coli APEC O1 4494745 YP_860074.1 CDS yjjK NC_008563.1 5069272 5070939 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(5069272..5070939) Escherichia coli APEC O1 4494746 YP_860075.1 CDS slt NC_008563.1 5071146 5073083 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5071146..5073083 Escherichia coli APEC O1 4494747 YP_860076.1 CDS trpR NC_008563.1 5073173 5073499 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5073173..5073499 Escherichia coli APEC O1 4494748 YP_860077.1 CDS yjjX NC_008563.1 5073572 5074108 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(5073572..5074108) Escherichia coli APEC O1 4494749 YP_860078.1 CDS gpmB NC_008563.1 5074151 5074798 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5074151..5074798 Escherichia coli APEC O1 4494750 YP_860079.1 CDS rob NC_008563.1 5074795 5075664 R right origin-binding protein complement(5074795..5075664) Escherichia coli APEC O1 4494751 YP_860080.1 CDS creA NC_008563.1 5075875 5076348 D hypothetical protein 5075875..5076348 Escherichia coli APEC O1 4494752 YP_860081.1 CDS creB NC_008563.1 5076361 5077050 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5076361..5077050 Escherichia coli APEC O1 4494753 YP_860082.1 CDS creC NC_008563.1 5077050 5078474 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5077050..5078474 Escherichia coli APEC O1 4494754 YP_860083.1 CDS creD NC_008563.1 5078532 5079884 D hypothetical protein 5078532..5079884 Escherichia coli APEC O1 4494755 YP_860084.1 CDS arcA NC_008563.1 5079944 5080660 R two-component response regulator complement(5079944..5080660) Escherichia coli APEC O1 4495365 YP_860085.1 CDS lasT NC_008563.1 5081296 5081982 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5081296..5081982 Escherichia coli APEC O1 4495366 YP_001481156.1 CDS insA NC_009837.1 27 239 D IS1 InsA protein; similar to CAA11401; hypothetical protein 27..239 Escherichia coli APEC O1 5616509 YP_001481157.1 CDS insB NC_009837.1 250 753 D IS1 InsB protein; identified by match to protein family HMM PF03400; similar to AAK09058; hypothetical protein 250..753 Escherichia coli APEC O1 5616510 YP_001481158.2 CDS sopA NC_009837.1 1053 2219 D stabilization of plasmid protein A; identified by match to protein family HMM PF01656; similar to NP_866033; plasmid-partitioning protein SopA 1053..2219 Escherichia coli APEC O1 5616511 YP_001481159.1 CDS sopB NC_009837.1 2219 3190 D stabilization of plasmid protein B; identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; SopB; plasmid-partitioning protein 2219..3190 Escherichia coli APEC O1 5616512 YP_001481160.1 CDS APECO1_O1CoBM5 NC_009837.1 3775 4035 D hypothetical protein 3775..4035 Escherichia coli APEC O1 5616513 YP_001481161.1 CDS insL NC_009837.1 4146 5264 R transposase for IS186; similar to AAC75453; identified by match to protein family HMM PF01609; InsL complement(4146..5264) Escherichia coli APEC O1 5616514 YP_001481162.1 CDS APECO1_O1CoBM7 NC_009837.1 5311 5826 D putative antirestriction protein; similar to AAO49634; identified by match to protein family HMM PF03230; hypothetical protein 5311..5826 Escherichia coli APEC O1 5616515 YP_001481163.1 CDS APECO1_O1CoBM8 NC_009837.1 5917 6288 D similar to BAA84887; hypothetical protein 5917..6288 Escherichia coli APEC O1 5616516 YP_001481164.1 CDS APECO1_O1CoBM9 NC_009837.1 6624 6968 R similar to AAO49636; hypothetical protein complement(6624..6968) Escherichia coli APEC O1 5616517 YP_001481165.1 CDS APECO1_O1CoBM10 NC_009837.1 7482 7742 R similar to YP_053128; hypothetical protein complement(7482..7742) Escherichia coli APEC O1 5616518 YP_001481166.1 CDS APECO1_O1CoBM11 NC_009837.1 7746 9107 D putative hydrolase; similar to YP_194824; hypothetical protein 7746..9107 Escherichia coli APEC O1 5616519 YP_001481167.1 CDS APECO1_O1CoBM12 NC_009837.1 9155 9718 D similar to ZP00719055; adenine-specific DNA methylase 9155..9718 Escherichia coli APEC O1 5616520 YP_001481168.1 CDS APECO1_O1CoBM13 NC_009837.1 10133 10381 D similar to AAO49639; hypothetical protein 10133..10381 Escherichia coli APEC O1 5616521 YP_001481169.1 CDS ssb NC_009837.1 10570 11136 D single-stranded binding protein; similar to AAO49641; identified by match to protein family HMM PF00436; single-stranded DNA-binding protein 10570..11136 Escherichia coli APEC O1 5616522 YP_001481170.1 CDS APECO1_O1CoBM15 NC_009837.1 11165 11425 D similar to AAR05684; identified by match to protein family HMM PF06006; hypothetical protein 11165..11425 Escherichia coli APEC O1 5616523 YP_001481171.1 CDS APECO1_O1CoBM16 NC_009837.1 11478 13442 D putative transcriptional regulator; similar to AAR05685; hypothetical protein 11478..13442 Escherichia coli APEC O1 5616524 YP_001481172.1 CDS psiB NC_009837.1 13494 13931 D plasmid SOS inhibition protein; similar to AAR25067; identified by match to protein family HMM PF06290; plasmid SOS inhibition protein B 13494..13931 Escherichia coli APEC O1 5616525 YP_001481173.1 CDS psiA NC_009837.1 13928 14647 D plasmid SOS inhibition protein; similar to AAO49644; identified by match to protein family HMM PF06952; PsiA; plasmid SOS inhibition protein A 13928..14647 Escherichia coli APEC O1 5616526 YP_001481174.1 CDS sok NC_009837.1 14659 14883 R suppression of killing; similar to SOK_ECOLI; hypothetical protein complement(14659..14883) Escherichia coli APEC O1 5616527 YP_001481175.1 CDS mok NC_009837.1 14869 15081 D modulator protein; similar to AAO49646; Mok; similar to F leading maintenance protein C; modulator of post-segregation killing protein 14869..15081 Escherichia coli APEC O1 5616528 YP_001481176.1 CDS APECO1_O1CoBM21 NC_009837.1 15305 15535 D hypothetical protein 15305..15535 Escherichia coli APEC O1 5616529 YP_001481177.1 CDS APECO1_O1CoBM22 NC_009837.1 15532 15774 D similar to AAR05690; hypothetical protein 15532..15774 Escherichia coli APEC O1 5616530 YP_001481178.1 CDS APECO1_O1CoBM23 NC_009837.1 16007 16294 D similar to AAO49511; hypothetical protein 16007..16294 Escherichia coli APEC O1 5616531 YP_001481179.1 CDS APECO1_O1CoBM24 NC_009837.1 16301 17236 D similar to YP_190149; identified by match to protein family HMM PF06067; hypothetical protein 16301..17236 Escherichia coli APEC O1 5616532 YP_001481180.1 CDS APECO1_O1CoBM25 NC_009837.1 17533 18135 R similar to YP_190148; identified by match to protein family HMM PF01464; lytic transglycosylase complement(17533..18135) Escherichia coli APEC O1 5616533 YP_001481181.1 CDS traM NC_009837.1 18456 18839 D conjugal transfer protein; similar to AAO49514; identified by match to protein family HMM PF05261; conjugal transfer protein TraM 18456..18839 Escherichia coli APEC O1 5616534 YP_001481182.1 CDS traJ NC_009837.1 19026 19715 D positive regulator of conjugative transfer; similar to AAO49515; conjugal transfer transcriptional regulator TraJ 19026..19715 Escherichia coli APEC O1 5616535 YP_001481183.1 CDS traY NC_009837.1 19808 20209 D conjugal transfer protein; similar to AAO49516; identified by match to protein family HMM PF05509; conjugal transfer protein TraY 19808..20209 Escherichia coli APEC O1 5616536 YP_001481184.1 CDS traA NC_009837.1 20242 20607 D pilin protein; similar to AAO49517; identified by match to protein family HMM PF05513; conjugal transfer pilin subunit TraA 20242..20607 Escherichia coli APEC O1 5616537 YP_001481185.1 CDS traL NC_009837.1 20622 20933 D conjugal transfer protein; similar to AAO49518; identified by match to protein family HMM PF07178; conjugal transfer pilus assembly protein TraL 20622..20933 Escherichia coli APEC O1 5616538 YP_001481186.1 CDS traE NC_009837.1 20955 21521 D conjugal transfer protein; similar to AAO49519; identified by match to protein family HMM PF05309; conjugal transfer pilus assembly protein TraE 20955..21521 Escherichia coli APEC O1 5616539 YP_001481187.1 CDS traK NC_009837.1 21508 22236 D conjugal transfer protein; similar to AAO49520; identified by match to protein family HMM PF06586; conjugal transfer protein TraK 21508..22236 Escherichia coli APEC O1 5616540 YP_001481188.1 CDS traB NC_009837.1 22236 23663 D conjugal transfer protein; similar to AAO49521; identified by match to protein family HMM PF06447; conjugal transfer pilus assembly protein TraB 22236..23663 Escherichia coli APEC O1 5616541 YP_001481189.1 CDS traP NC_009837.1 23653 24243 D conjugal transfer protein; similar to AAO49522; identified by match to protein family HMM PF07296; conjugal transfer protein TraP 23653..24243 Escherichia coli APEC O1 5616542 YP_001481190.1 CDS trbD NC_009837.1 24197 24427 D conjugal transfer protein; similar to AAO49523; conjugal transfer protein TrbD 24197..24427 Escherichia coli APEC O1 5616543 YP_001481191.1 CDS trbG NC_009837.1 24439 24690 D conjugal transfer protein; similar to AAO49524; conjugal transfer protein TrbG 24439..24690 Escherichia coli APEC O1 5616544 YP_001481192.1 CDS traV NC_009837.1 24687 25202 D conjugal transfer protein; similar to AAO49525; conjugal transfer protein TraV 24687..25202 Escherichia coli APEC O1 5616545 YP_001481193.1 CDS traR NC_009837.1 25337 25558 D conjugal transfer protein; similar to AAO49526; conjugal transfer protein TraR 25337..25558 Escherichia coli APEC O1 5616546 YP_001481194.1 CDS traC NC_009837.1 25718 28345 D pilus assembly and synthesis; similar to AAO49527; similar to VirB4; conjugal transfer ATP-binding protein TraC 25718..28345 Escherichia coli APEC O1 5616547 YP_001481195.1 CDS trbI NC_009837.1 28342 28728 D conjugal transfer protein; similar to AAO49648; conjugal transfer protein TrbI 28342..28728 Escherichia coli APEC O1 5616548 YP_001481196.2 CDS traW NC_009837.1 28725 29357 D conjugal transfer protein; similar to AAO49528; conjugal transfer pilus assembly protein TraW 28725..29357 Escherichia coli APEC O1 5616549 YP_001481197.1 CDS traU NC_009837.1 29354 30346 D conjugal transfer protein; similar to AAO49529; identified by match to protein family HMM PF06834; conjugal transfer pilus assembly protein TraU 29354..30346 Escherichia coli APEC O1 5616550 YP_001481198.1 CDS trbC NC_009837.1 30352 30993 D periplasmic protein; similar to AAC44205; conjugal transfer pilus assembly protein TrbC 30352..30993 Escherichia coli APEC O1 5616551 YP_001481199.1 CDS traN NC_009837.1 30990 32798 D mating pair stabilization protein; similar to AAO49531; identified by match to protein family HMM PF06986; TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 30990..32798 Escherichia coli APEC O1 5616552 YP_001481200.1 CDS trbE NC_009837.1 32822 33082 D conjugal transfer protein; similar to AAO49532; conjugal transfer protein TrbE 32822..33082 Escherichia coli APEC O1 5616553 YP_001481201.1 CDS traF NC_009837.1 33045 33818 D conjugal transfer protein; similar to AAO49533; type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal pilus assembly protein TraF 33045..33818 Escherichia coli APEC O1 5616554 YP_001481202.1 CDS trbA NC_009837.1 33834 34181 D conjugal transfer protein; similar to AAO49534; conjugal transfer protein TrbA 33834..34181 Escherichia coli APEC O1 5616555 YP_001481203.1 CDS artA NC_009837.1 34183 34458 R conserved hypothetical protein; similar to AAC44178; hypothetical protein complement(34183..34458) Escherichia coli APEC O1 5616556 YP_001481204.1 CDS traQ NC_009837.1 34584 34820 D pilin chaperone protein; similar to AAO49536; conjugal transfer pilin chaperone TraQ 34584..34820 Escherichia coli APEC O1 5616557 YP_001481205.1 CDS trbB NC_009837.1 34807 35352 D conjugal transfer protein; similar to AAR25104; conjugal transfer protein TrbB 34807..35352 Escherichia coli APEC O1 5616558 YP_001481206.1 CDS trbJ NC_009837.1 35282 35623 D conjugal transfer protein; similar to AAO49538; conjugal transfer protein TrbJ 35282..35623 Escherichia coli APEC O1 5616559 YP_001481207.1 CDS trbF NC_009837.1 35663 35968 R conjugal transfer protein; similar to AAO49539; hypothetical protein complement(35663..35968) Escherichia coli APEC O1 5616560 YP_001481208.1 CDS traG NC_009837.1 35989 40185 D pilus assembly protein; similar to YP_190118; identified by match to protein family HMM PF06122; hypothetical protein 35989..40185 Escherichia coli APEC O1 5616561 YP_001481209.1 CDS traS NC_009837.1 40182 40691 D surface exclusion protein; similar to AAO49542; conjugal transfer entry exclusion protein TraS 40182..40691 Escherichia coli APEC O1 5616562 YP_001481210.1 CDS traT NC_009837.1 40705 41436 D surface exclusion and complement resistance protein; similar to AAT85681; identified by match to protein family HMM PF05818; conjugal transfer surface exclusion protein TraT 40705..41436 Escherichia coli APEC O1 5616563 YP_001481211.1 CDS traD NC_009837.1 41689 43842 D coupling protein; similar to AAC44181; type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD 41689..43842 Escherichia coli APEC O1 5616566 YP_001481212.1 CDS trbH NC_009837.1 43842 44561 D conserved hypothetical protein; similar to AAP79033; identified by match to protein family HMM PF01850; TrbH 43842..44561 Escherichia coli APEC O1 5616564 YP_001481213.1 CDS traI NC_009837.1 44537 49828 D DNA helicase I; similar to YP_190115; identified by match to protein family HMM PF07057; cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer nickase/helicase TraI 44537..49828 Escherichia coli APEC O1 5616565 YP_001481214.1 CDS traX NC_009837.1 49848 50594 D F pilin acetylase; similar to YP_190114; conjugal transfer pilus acetylation protein TraX 49848..50594 Escherichia coli APEC O1 5616567 YP_001481215.1 CDS APECO1_O1CoBM60 NC_009837.1 50653 51513 D putative hydrolase, alpha/beta fold family; similar to YP_190113; identified by match to protein family HMM PF00561; hypothetical protein 50653..51513 Escherichia coli APEC O1 5616568 YP_001481216.1 CDS finO NC_009837.1 51616 52176 D fertility inhibition protein; similar to YP_313451; identified by match to protein family HMM PF05286; conjugal transfer fertility inhibition protein FinO 51616..52176 Escherichia coli APEC O1 5616569 YP_001481217.1 CDS APECO1_O1CoBM62 NC_009837.1 52312 52524 D similar to YP_313453; hypothetical protein 52312..52524 Escherichia coli APEC O1 5616570 YP_001481218.1 CDS srnB NC_009837.1 53043 53354 D modulator of post-segregational killing; similar to BAA97874; hypothetical protein 53043..53354 Escherichia coli APEC O1 5616571 YP_001481219.1 CDS repA2 NC_009837.1 53638 53895 D replication regulatory protein; similar to BAA97876; replication protein 53638..53895 Escherichia coli APEC O1 5616572 YP_001481220.1 CDS repA3 NC_009837.1 53912 54214 R replication protein; similar to CAA23641; RepA3 complement(53912..54214) Escherichia coli APEC O1 5616573 YP_001481221.1 CDS repA NC_009837.1 54182 54676 D repFIC initiation protein; similar to AAA99008; hypothetical protein 54182..54676 Escherichia coli APEC O1 5616574 YP_001481222.2 CDS repA1 NC_009837.1 54669 55526 D replication protein; similar to AAO49555; identified by match to protein family HMM PF02387; IncFII replicon family; RepA; replication protein 54669..55526 Escherichia coli APEC O1 5616575 YP_001481223.1 CDS repA4 NC_009837.1 56095 56373 R replication protein; similar to NP_052991; hypothetical protein complement(56095..56373) Escherichia coli APEC O1 5616576 YP_001481224.1 CDS APECO1_O1CoBM69 NC_009837.1 56435 56740 D antitoxin of toxin stability system; similar to YP_313640; identified by match to protein family HMM PF02604; hypothetical protein 56435..56740 Escherichia coli APEC O1 5616577 YP_001481225.1 CDS relE NC_009837.1 56737 57024 D cytotoxic translational repressor; similar to YP_313641; identified by match to protein family HMM PF05016; hypothetical protein 56737..57024 Escherichia coli APEC O1 5616578 YP_001481226.1 CDS APECO1_O1CoBM71 NC_009837.1 57293 58183 R transposase for IS629; similar to CAD88882; identified by match to protein family HMM PF00665; hypothetical protein complement(57293..58183) Escherichia coli APEC O1 5616579 YP_001481227.1 CDS APECO1_O1CoBM72 NC_009837.1 58180 58506 R similar to NP_288505; hypothetical protein complement(58180..58506) Escherichia coli APEC O1 5616580 YP_001481228.1 CDS tsh NC_009837.1 58775 62908 D temperature sensitive hemagglutinin; similar to AAA24698; identified by match to protein family HMM PF02395; Tsh 58775..62908 Escherichia coli APEC O1 5616581 YP_001481229.1 CDS insA NC_009837.1 62991 63203 D transposase fro IS1; similar to CAE55752; hypothetical protein 62991..63203 Escherichia coli APEC O1 5616582 YP_001481230.1 CDS insB NC_009837.1 63214 63702 D IS1 InsB protein; similar to NP_863025; identified by match to protein family HMM PF03400; hypothetical protein 63214..63702 Escherichia coli APEC O1 5616583 YP_001481231.1 CDS APECO1_O1CoBM76 NC_009837.1 63773 64522 R similar to DQ269483; identified by match to protein family HMM PF01695; ISEc12 putative ATP-binding protein complement(63773..64522) Escherichia coli APEC O1 5616584 YP_001481232.1 CDS APECO1_O1CoBM77 NC_009837.1 64534 66075 R similar to DQ269483; identified by match to protein family HMM PF00665; putative transposase for ISEc12 complement(64534..66075) Escherichia coli APEC O1 5616585 YP_001481233.1 CDS APECO1_O1CoBM78 NC_009837.1 66313 67350 R similar to YP_194858; hypothetical protein complement(66313..67350) Escherichia coli APEC O1 5616586 YP_001481234.1 CDS APECO1_O1CoBM79 NC_009837.1 67335 68900 R similar to YP_194859; hypothetical protein complement(67335..68900) Escherichia coli APEC O1 5616587 YP_001481235.1 CDS vagD NC_009837.1 68894 69649 D virulence-associated gene D; similar to YP_194860; identified by match to protein family HMM PF01850; hypothetical protein 68894..69649 Escherichia coli APEC O1 5616588 YP_001481236.1 CDS APECO1_O1CoBM81 NC_009837.1 69950 70432 D putative acetyltransferase; similar to NP_761263; identified by match to protein family HMM PF04014; hypothetical protein 69950..70432 Escherichia coli APEC O1 5616589 YP_001481237.1 CDS APECO1_O1CoBM82 NC_009837.1 70464 71996 R putative dimethylaniline monoxygenase; similar to CAA11511; identified by match to protein family HMM PF00743; hypothetical protein complement(70464..71996) Escherichia coli APEC O1 5616590 YP_001481238.1 CDS APECO1_O1CoBM83 NC_009837.1 71817 72305 D similar to NP_875585; hypothetical protein 71817..72305 Escherichia coli APEC O1 5616591 YP_001481239.1 CDS APECO1_O1CoBM84 NC_009837.1 72264 73283 R putative oxidoreductase; similar to CAA11512; identified by match to protein family HMM PF01408; hypothetical protein complement(72264..73283) Escherichia coli APEC O1 5616592 YP_001481240.1 CDS APECO1_O1CoBM85 NC_009837.1 73283 74203 R putative hydrolase; similar to AAK03131; identified by match to protein family HMM TIGR01484; hypothetical protein complement(73283..74203) Escherichia coli APEC O1 5616593 YP_001481241.1 CDS APECO1_O1CoBM86 NC_009837.1 74094 75332 R putative aminotransferase; similar to NP_388936; identified by match to protein family HMM PF01041; hypothetical protein complement(74094..75332) Escherichia coli APEC O1 5616594 YP_001481242.1 CDS APECO1_O1CoBM87 NC_009837.1 75872 77005 D similar to NP_943348; hypothetical protein 75872..77005 Escherichia coli APEC O1 5616595 YP_001481243.1 CDS korC NC_009837.1 77025 77309 D conserved hypothetical protein; similar to NP_943347; hypothetical protein 77025..77309 Escherichia coli APEC O1 5616596 YP_001481244.1 CDS APECO1_O1CoBM89 NC_009837.1 77306 77503 R similar to NP_943346; hypothetical protein complement(77306..77503) Escherichia coli APEC O1 5616597 YP_001481245.1 CDS APECO1_O1CoBM90 NC_009837.1 77552 77761 R hypothetical protein complement(77552..77761) Escherichia coli APEC O1 5616598 YP_001481246.1 CDS APECO1_O1CoBM91 NC_009837.1 78075 78476 D similar to NP_755452; identified by match to protein family HMM PF01527; hypothetical protein 78075..78476 Escherichia coli APEC O1 5616599 YP_001481247.1 CDS APECO1_O1CoBM92 NC_009837.1 78473 78820 D putative transposase of ISEc8; identified by match to protein family HMM PF05717; hypothetical protein 78473..78820 Escherichia coli APEC O1 5616600 YP_001481248.1 CDS APECO1_O1CoBM93 NC_009837.1 78870 80408 D putative transposase; identified by match to protein family HMM PF03050; hypothetical protein 78870..80408 Escherichia coli APEC O1 5616601 YP_001481249.1 CDS APECO1_O1CoBM94 NC_009837.1 80524 80802 D similar to NP_085375; identified by match to protein family HMM PF01527; hypothetical protein 80524..80802 Escherichia coli APEC O1 5616602 YP_001481250.1 CDS APECO1_O1CoBM95 NC_009837.1 80760 81665 D IS2 transposase; similar to NP_418693; identified by match to protein family HMM PF00665; IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 80760..81665 Escherichia coli APEC O1 5616603 YP_001481251.1 CDS APECO1_O1CoBM96 NC_009837.1 81930 85427 D putative adhesin; similar to BAB33785; identified by match to protein family HMM PF03212; match to protein family HMM PF03797; hypothetical protein 81930..85427 Escherichia coli APEC O1 5616604 YP_001481252.1 CDS APECO1_O1CoBM97 NC_009837.1 85574 85900 D similar to NP_288505; hypothetical protein 85574..85900 Escherichia coli APEC O1 5616605 YP_001481253.1 CDS APECO1_O1CoBM98 NC_009837.1 85922 86767 D IS629 transposase; similar to CAD88882; identified by match to protein family HMM PF00665; transposase 85922..86767 Escherichia coli APEC O1 5616606 YP_001481254.1 CDS eitD NC_009837.1 86860 88182 R putative iron transport system, membrane component; similar to ABA54770; identified by match to protein family HMM PF07690; EitD complement(86860..88182) Escherichia coli APEC O1 5616607 YP_001481255.1 CDS eitC NC_009837.1 88104 88868 R putative iron transport system, ATP-binding component; similar to AAX22060; identified by match to protein family HMM PF00005; EitC complement(88104..88868) Escherichia coli APEC O1 5616608 YP_001481256.1 CDS eitB NC_009837.1 88865 89902 R putative iron transport system, permease component; similar to AAX22061; identified by match to protein family HMM PF01032; EitB complement(88865..89902) Escherichia coli APEC O1 5616609 YP_001481257.1 CDS eitA NC_009837.1 89902 90900 R putative iron transport system, periplasmic binding protein; similar to AAX22062; identified by match to protein family HMM PF01497; EitA complement(89902..90900) Escherichia coli APEC O1 5616610 YP_001481258.1 CDS APECO1_O1CoBM103 NC_009837.1 91255 91845 R similar to EAN42275; identified by match to protein family HMM PF00239; resolvase complement(91255..91845) Escherichia coli APEC O1 5616611 YP_001481259.1 CDS APECO1_O1CoBM104 NC_009837.1 92346 92630 D similar to AAC70078; identified by match to protein family HMM PF01402; ribbon-helix-helix protein, copG family domain; hypothetical protein 92346..92630 Escherichia coli APEC O1 5616612 YP_001481260.1 CDS APECO1_O1CoBM105 NC_009837.1 92630 92905 D similar to AAT94182; identified by match to protein family HMM PF05016; putative plasmid stabilization system protein; hypothetical protein 92630..92905 Escherichia coli APEC O1 5616613 YP_001481261.1 CDS APECO1_O1CoBM106 NC_009837.1 92987 93244 R similar to AAT94181; hypothetical protein complement(92987..93244) Escherichia coli APEC O1 5616614 YP_001481262.1 CDS APECO1_O1CoBM107 NC_009837.1 93413 94240 R IS1294 transposase; similar to AAM14707; transposase complement(93413..94240) Escherichia coli APEC O1 5616615 YP_001481263.1 CDS APECO1_O1CoBM108 NC_009837.1 94303 94704 R similar to ZP_00714559; hypothetical protein complement(94303..94704) Escherichia coli APEC O1 5616616 YP_001481264.1 CDS APECO1_O1CoBM109 NC_009837.1 94722 94952 D hypothetical protein 94722..94952 Escherichia coli APEC O1 5616617 YP_001481265.1 CDS APECO1_O1CoBM110 NC_009837.1 94942 97080 D similar to AAP42487; hypothetical protein 94942..97080 Escherichia coli APEC O1 5616618 YP_001481266.1 CDS vagD NC_009837.1 97242 97658 R virulence-associated gene D; similar to AAP42488; identified by match to protein family HMM PF01850; hypothetical protein complement(97242..97658) Escherichia coli APEC O1 5616619 YP_001481267.1 CDS vagC NC_009837.1 97655 97885 R virulence associated gene C; similar to AAP42489; identified by match to protein family HMM PF04014; hypothetical protein complement(97655..97885) Escherichia coli APEC O1 5616620 YP_001481268.1 CDS APECO1_O1CoBM113 NC_009837.1 97973 98176 D hypothetical protein 97973..98176 Escherichia coli APEC O1 5616621 YP_001481269.1 CDS APECO1_O1CoBM114 NC_009837.1 98447 98797 D similar to AAO49566; hypothetical protein 98447..98797 Escherichia coli APEC O1 5616622 YP_001481270.1 CDS APECO1_O1CoBM115 NC_009837.1 98841 99530 D similar to AAO49564; hypothetical protein 98841..99530 Escherichia coli APEC O1 5616623 YP_001481271.1 CDS APECO1_O1CoBM116 NC_009837.1 99527 100318 D putative site-specific recombinase; similar to YP_190186; identified by match to protein family HMM PF00589; resolvase 99527..100318 Escherichia coli APEC O1 5616624 YP_001481272.1 CDS cmi NC_009837.1 100424 100849 D colicin M immunity protein; similar to IMMM_ECOLI; Cmi 100424..100849 Escherichia coli APEC O1 5616625 YP_001481273.1 CDS cma NC_009837.1 100899 101714 R colicin M activity protein; similar to CEAM_ECOLI; hypothetical protein complement(100899..101714) Escherichia coli APEC O1 5616626 YP_001481274.1 CDS cbi NC_009837.1 101958 102485 D colicin B immunity protein; similar to IMMB_ECOLI; Cbi 101958..102485 Escherichia coli APEC O1 5616627 YP_001481275.1 CDS cba NC_009837.1 102518 102637 D colicin B activity protein; similar to CEAB_ECOLI; Cba 102518..102637 Escherichia coli APEC O1 5616629 YP_001481276.1 CDS APECO1_O1CoBM121 NC_009837.1 102843 103124 D similar to AAT94181; hypothetical protein 102843..103124 Escherichia coli APEC O1 5616630 YP_001481277.1 CDS APECO1_O1CoBM122 NC_009837.1 103507 103695 R hypothetical protein complement(103507..103695) Escherichia coli APEC O1 5616628 YP_001481278.1 CDS cvaB NC_009837.1 103670 105241 R fusion between colicin V secretion protein and transposase for IS186; assembly verified for accuracy; amino acids 1-195 are similar to 1-195 of IS186 transposase, amino acids 198-523 are similar to 45-362 of cvaB; similar to identified by match to protein family HMM PF01609; CvaB, IS186 transposase complement(103670..105241) Escherichia coli APEC O1 5616631 YP_001481279.1 CDS cvaA NC_009837.1 105216 106457 R colicin V secretion protein; similar to CAA40743; identified by match to protein family HMM PF00529; CvaA complement(105216..106457) Escherichia coli APEC O1 5616632 YP_001481280.1 CDS insD NC_009837.1 106687 107592 R transposase for IS2; similar to NP_418693; identified by match to protein family HMM PF00665; InsD complement(106687..107592) Escherichia coli APEC O1 5616633 YP_001481281.1 CDS insL NC_009837.1 107550 107960 R IS2 transposase subunit; similar to NP_839581; identified by match to protein family HMM PF01527; IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(107550..107960) Escherichia coli APEC O1 5616634 YP_001481282.1 CDS APECO1_O1CoBM127 NC_009837.1 108234 108443 R similar to AAX22082; hypothetical protein complement(108234..108443) Escherichia coli APEC O1 5616635 YP_001481283.1 CDS yacA NC_009837.1 108437 108706 D unknown function; similar to AAZ05342; YacA 108437..108706 Escherichia coli APEC O1 5616636 YP_001481284.1 CDS yacB NC_009837.1 108703 108984 D plasmid stabilization system protein, RelE/ParE family superfamily; similar to YP_190105; identified by match to protein family HMM PF05016; YacB 108703..108984 Escherichia coli APEC O1 5616637 YP_001481285.1 CDS yacC NC_009837.1 109030 109878 D putative transposase; identified by match to protein family HMM PF00929; YacC 109030..109878 Escherichia coli APEC O1 5616638 YP_001481286.1 CDS APECO1_O1CoBM130a NC_009837.1 109995 110477 D putative cytoplasmic protein; similar to AAZ05345; YadA 109995..110477 Escherichia coli APEC O1 5616639 YP_001481287.1 CDS APECO1_O1CoBM131 NC_009837.1 110779 111126 D similar to YP_308785; hypothetical protein 110779..111126 Escherichia coli APEC O1 5616707 YP_001481288.1 CDS APECO1_O1CoBM132 NC_009837.1 111130 111327 D similar to AAX22086; hypothetical protein 111130..111327 Escherichia coli APEC O1 5616640 YP_001481289.1 CDS APECO1_O1CoBM133 NC_009837.1 111476 111667 D hypothetical protein 111476..111667 Escherichia coli APEC O1 5616641 YP_001481290.1 CDS APECO1_O1CoBM134 NC_009837.1 111685 112626 D similar to CAC43413; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 111685..112626 Escherichia coli APEC O1 5616642 YP_001481291.1 CDS APECO1_O1CoBM135 NC_009837.1 112641 112841 D similar to NP_753138; hypothetical protein 112641..112841 Escherichia coli APEC O1 5616643 YP_001481292.1 CDS APECO1_O1CoBM136 NC_009837.1 113050 113277 R similar to AAX22088; hypothetical protein complement(113050..113277) Escherichia coli APEC O1 5616644 YP_001481293.1 CDS iroN NC_009837.1 113575 115752 D salmochelin siderophore system, salmochelin receptor; similar to AAS80269; identified by match to protein family HMM PF00593; Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 113575..115752 Escherichia coli APEC O1 5616645 YP_001481294.1 CDS APECO1_O1CoBM138 NC_009837.1 115797 116753 R salmochelin siderophore system component; similar to AAP42473; hypothetical protein complement(115797..116753) Escherichia coli APEC O1 5616646 YP_001481295.1 CDS iroD NC_009837.1 116838 118067 R salmochelin siderophore system, ferric enterochelin esterase; similar to AAS80267; identified by match to protein family HMM PF; IroD complement(116838..118067) Escherichia coli APEC O1 5616647 YP_001481296.1 CDS iroC NC_009837.1 118171 121956 R salmochelin siderophore system, ATP-binding cassette; similar to AAP41471; identified by match to protein family HMM PF00005; IroC complement(118171..121956) Escherichia coli APEC O1 5616648 YP_001481297.1 CDS iroB NC_009837.1 121970 123133 R salmochelin siderophore system, glycosyltransferase; similar to AAS80265; identified by match to protein family HMM PF06722; IroB complement(121970..123133) Escherichia coli APEC O1 5616649 YP_001481298.1 CDS APECO1_O1CoBM142 NC_009837.1 123284 123553 R similar to AAS80264; hypothetical protein complement(123284..123553) Escherichia coli APEC O1 5616650 YP_001481299.1 CDS APECO1_O1CoBM143 NC_009837.1 124321 124881 R putative integrase; similar to AAP42475; identified by match to protein family HMM PF00665; hypothetical protein complement(124321..124881) Escherichia coli APEC O1 5616651 YP_001481300.1 CDS APECO1_O1CoBM144 NC_009837.1 125072 125365 R similar to AAP42476; hypothetical protein complement(125072..125365) Escherichia coli APEC O1 5616652 YP_001481301.1 CDS APECO1_O1CoBM145 NC_009837.1 125931 126224 R similar to AAP41478; hypothetical protein complement(125931..126224) Escherichia coli APEC O1 5616653 YP_001481302.1 CDS iss NC_009837.1 126237 126545 R increased serum survival protein; involved in complement resistance; similar to AAS80261; identified by match to protein family; Iss complement(126237..126545) Escherichia coli APEC O1 5616654 YP_001481303.1 CDS APECO1_O1CoBM147 NC_009837.1 126696 126884 D similar to AAX22091; hypothetical protein 126696..126884 Escherichia coli APEC O1 5616655 YP_001481304.1 CDS insL NC_009837.1 127112 127522 D putative transposase; similar to NP_418692; identified by match to protein family HMM PF01527; IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 127112..127522 Escherichia coli APEC O1 5616656 YP_001481305.1 CDS insD NC_009837.1 127480 128385 D IS2 transposase; similar to AAO49621; identified by match to protein family HMM PF00665; InsD 127480..128385 Escherichia coli APEC O1 5616657 YP_001481306.1 CDS APECO1_O1CoBM150 NC_009837.1 128970 129194 D hypothetical protein 128970..129194 Escherichia coli APEC O1 5616658 YP_001481307.1 CDS APECO1_O1CoBM151 NC_009837.1 129609 130802 D cobalamin synthesis protein cobW C-terminal domain; similar to AAX22904; identified by match to protein family HMM PF02492; hypothetical protein 129609..130802 Escherichia coli APEC O1 5616659 YP_001481308.1 CDS APECO1_O1CoBM152 NC_009837.1 130935 131252 D similar to AAX22096; hypothetical protein 130935..131252 Escherichia coli APEC O1 5616660 YP_001481309.1 CDS APECO1_O1CoBM153 NC_009837.1 131439 132305 D similar to AAX22097; hypothetical protein 131439..132305 Escherichia coli APEC O1 5616661 YP_001481310.1 CDS APECO1_O1CoBM154 NC_009837.1 132442 132828 D similar to AAX22097; hypothetical protein 132442..132828 Escherichia coli APEC O1 5616662 YP_001481311.1 CDS APECO1_O1CoBM155 NC_009837.1 132865 133053 D hypothetical protein 132865..133053 Escherichia coli APEC O1 5616663 YP_001481312.1 CDS APECO1_O1CoBM156 NC_009837.1 133063 134004 D similar to YP_268363; hypothetical protein 133063..134004 Escherichia coli APEC O1 5616664 YP_001481313.1 CDS APECO1_O1CoBM157 NC_009837.1 134100 134327 R hypothetical protein complement(134100..134327) Escherichia coli APEC O1 5616665 YP_001481314.1 CDS insB NC_009837.1 134716 135219 R IS1 transposase; similar to AAO49620; identified by match to protein family HMM PF03400; hypothetical protein complement(134716..135219) Escherichia coli APEC O1 5616666 YP_001481315.1 CDS APECO1_O1CoBM159 NC_009837.1 135138 135413 R IS1 InsA protein; similar to AAO49621; hypothetical protein complement(135138..135413) Escherichia coli APEC O1 5616667 YP_001481316.1 CDS APECO1_O1CoBM160 NC_009837.1 135927 137429 R similar to AAO49625; hypothetical protein complement(135927..137429) Escherichia coli APEC O1 5616670 YP_001481317.1 CDS APECO1_O1CoBM161 NC_009837.1 137715 137924 D hypothetical protein 137715..137924 Escherichia coli APEC O1 5616669 YP_001481318.1 CDS APECO1_O1CoBM162 NC_009837.1 138064 138513 R hypothetical protein complement(138064..138513) Escherichia coli APEC O1 5616671 YP_001481319.1 CDS APECO1_O1CoBM163 NC_009837.1 138631 139110 D similar to AAO49623; hypothetical protein 138631..139110 Escherichia coli APEC O1 5616672 YP_001481320.1 CDS APECO1_O1CoBM164 NC_009837.1 139550 140212 D hypothetical protein 139550..140212 Escherichia coli APEC O1 5616673 YP_001481321.1 CDS insB NC_009837.1 140223 140726 R IS1 transposase; similar to AAO49620; identified by match to protein family HMM PF03400; hypothetical protein complement(140223..140726) Escherichia coli APEC O1 5616674 YP_001481322.1 CDS APECO1_O1CoBM166 NC_009837.1 140645 140920 R IS1 InsA protein; similar to AAO49621; hypothetical protein complement(140645..140920) Escherichia coli APEC O1 5616675 YP_001481323.1 CDS APECO1_O1CoBM167 NC_009837.1 141032 141304 D similar to ABA54745; hypothetical protein 141032..141304 Escherichia coli APEC O1 5616668 YP_001481324.1 CDS iutA NC_009837.1 141445 143646 R aerobactin siderophore system, ferric aerobactin receptor protein; similar to ABA54744; identified by match to protein family HMM PF00593; IutA complement(141445..143646) Escherichia coli APEC O1 5616676 YP_001481325.1 CDS iucD NC_009837.1 143728 145005 R aerobactin siderophore system, L-lysine 6-monooxygenase; similar to CAE55774; IucD complement(143728..145005) Escherichia coli APEC O1 5616677 YP_001481326.1 CDS iucC NC_009837.1 145002 146744 R aerobactin siderophore system, aerobactin biosynthesis protein; similar to ABA54742; identified by match to protein family HMMPFO4183; IucC complement(145002..146744) Escherichia coli APEC O1 5616678 YP_001481327.1 CDS APECO1_O1CoBM171 NC_009837.1 146744 147691 R aerobactin siderophore system, N-hydroxylysine acetylase; similar to ABA54741; IucB complement(146744..147691) Escherichia coli APEC O1 5616679 YP_001481328.1 CDS iucA NC_009837.1 147692 149473 R aerobactin siderophore system, aerobactin synthetase; similar to ABA54740; identified by match to protein family HMM PF04183; IucA complement(147692..149473) Escherichia coli APEC O1 5616680 YP_001481329.1 CDS shiF NC_009837.1 149552 150745 D transporter, major facilitator family subfamily; similar to AAZ29623; identified by match to protein family HMM PF07690; ShiF 149552..150745 Escherichia coli APEC O1 5616681 YP_001481330.1 CDS crcB NC_009837.1 151126 151506 R similar to CAH64818; identified by match to protein family HMM PF02537; may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(151126..151506) Escherichia coli APEC O1 5616682 YP_001481331.1 CDS APECO1_O1CoBM175 NC_009837.1 151578 151850 R similar to ABA54737; hypothetical protein complement(151578..151850) Escherichia coli APEC O1 5616683 YP_001481332.1 CDS eno NC_009837.1 151847 152176 R putative enolase, C-terminal TIM barrel domain; similar to CAH64819; identified by match to protein family HMM PF00113; hypothetical protein complement(151847..152176) Escherichia coli APEC O1 5616684 YP_001481333.1 CDS sitD NC_009837.1 152749 153606 R ABC iron transport system, inner membrane component; similar to ABA54734; identified by match to protein family HMM PF00950; SitD complement(152749..153606) Escherichia coli APEC O1 5616685 YP_001481334.1 CDS sitC NC_009837.1 153603 154460 R ABC iron transport system, permease component; similar to AAT11266; identified by match to protein family HMM PF00950; SitC complement(153603..154460) Escherichia coli APEC O1 5616686 YP_001481335.1 CDS sitB NC_009837.1 154457 155284 R ABC iron transport system, ATP-binding component; similar to ABA54732; identified by match to protein family HMM PF00005; SitB complement(154457..155284) Escherichia coli APEC O1 5616687 YP_001481336.1 CDS sitA NC_009837.1 155284 156198 R ABC iron transport system, periplasmic binding protein; similar to AAT11264; identified by match to protein family HMM PF01297; SitA complement(155284..156198) Escherichia coli APEC O1 5616688 YP_001481337.1 CDS insA NC_009837.1 156554 156829 D IS1 InsA protein; similar to AAO49621; hypothetical protein 156554..156829 Escherichia coli APEC O1 5616689 YP_001481338.1 CDS insB NC_009837.1 156748 157251 D IS1 transposase; similar to AAO49620; hypothetical protein 156748..157251 Escherichia coli APEC O1 5616690 YP_001481339.1 CDS APECO1_O1CoBM183 NC_009837.1 157431 157778 R similar to AAO49619; hypothetical protein complement(157431..157778) Escherichia coli APEC O1 5616691 YP_001481340.1 CDS APECO1_O1CoBM184 NC_009837.1 158078 158434 R IS21 transposase; similar to AAO49618; transposase complement(158078..158434) Escherichia coli APEC O1 5616692 YP_001481341.1 CDS APECO1_O1CoBM185 NC_009837.1 158475 158771 D similar to AAR05705; hypothetical protein 158475..158771 Escherichia coli APEC O1 5616693 YP_001481342.1 CDS repA NC_009837.1 159180 160157 D repFIB replication protein; similar to AAO49616; identified by match to protein family HMM PF01051; hypothetical protein 159180..160157 Escherichia coli APEC O1 5616694 YP_001481343.1 CDS int NC_009837.1 160442 161182 R site-specific integrase; similar to AAO49615; identified by match to protein family HMM PF00589; hypothetical protein complement(160442..161182) Escherichia coli APEC O1 5616695 YP_001481344.1 CDS APECO1_O1CoBM188 NC_009837.1 161865 162773 R putative transcriptional regulator; similar to AAO49614; identified by match to protein family HMM PF07395; hypothetical protein complement(161865..162773) Escherichia coli APEC O1 5616696 YP_001481345.1 CDS hlyF NC_009837.1 162836 163945 R putative avian hemolysin; similar to AAO49613; identified by match to protein family HMM PF01073; HlyF complement(162836..163945) Escherichia coli APEC O1 5616697 YP_001481346.1 CDS APECO1_O1CoBM190 NC_009837.1 164004 164288 D hypothetical protein 164004..164288 Escherichia coli APEC O1 5616698 YP_001481347.1 CDS ompT NC_009837.1 165436 165825 D outer membrane protease; similar to ABA54754; identified by match to protein family HMM PF01278; OmpT 165436..165825 Escherichia coli APEC O1 5616699 YP_001481348.1 CDS APECO1_O1CoBM193 NC_009837.1 166196 166456 R similar to ABA54756; hypothetical protein complement(166196..166456) Escherichia coli APEC O1 5616706 YP_001481349.1 CDS APECO1_O1CoBM194 NC_009837.1 166967 167293 D similar to NP_288505; hypothetical protein 166967..167293 Escherichia coli APEC O1 5616700 YP_001481350.1 CDS APECO1_O1CoBM195 NC_009837.1 167290 168180 D similar to CAD88882; identified by match to protein family HMM PF00665; IS629 transposase 167290..168180 Escherichia coli APEC O1 5616701 YP_001481351.1 CDS APECO1_O1CoBM196 NC_009837.1 168450 168740 R hypothetical protein complement(168450..168740) Escherichia coli APEC O1 5616702 YP_001481352.1 CDS etsA NC_009837.1 169634 170821 D E. coli transport system, membrane fusion protein; similar to ABA54761; identified by match to protein family HMM PF00529; EtsA 169634..170821 Escherichia coli APEC O1 5616703 YP_001481353.1 CDS etsB NC_009837.1 170818 172758 D E. coli transport system, ATP-binding/permease protein; similar to ABA54762; identified by match to protein family HMM PF00005; EtsB 170818..172758 Escherichia coli APEC O1 5616704 YP_001481354.1 CDS etsC NC_009837.1 172762 174132 D E. coli transport system, efflux protein; similar to ABA54763; identified by match to protein family HMM PF02321; EtsC 172762..174132 Escherichia coli APEC O1 5616705 YP_001481355.1 CDS repA NC_009838.1 1 876 D putative replication protein; hypothetical protein 1..876 Escherichia coli APEC O1 5616708 YP_001481356.1 CDS htdZ NC_009838.1 1998 2378 D putative pilin presursor; HtdZ 1998..2378 Escherichia coli APEC O1 5616712 YP_001481357.1 CDS trhL NC_009838.1 2396 2746 D putative plasmid transfer protein; TrhL 2396..2746 Escherichia coli APEC O1 5616713 YP_001481358.1 CDS trhE NC_009838.1 2758 3546 D putative pilus assembly protein; TrhE 2758..3546 Escherichia coli APEC O1 5616714 YP_001481359.1 CDS trhK NC_009838.1 3543 4817 D TrhK 3543..4817 Escherichia coli APEC O1 5616715 YP_001481360.1 CDS htdO NC_009838.1 4819 5280 D HtdO 4819..5280 Escherichia coli APEC O1 5616716 YP_001481361.1 CDS trhB NC_009838.1 5258 6625 D putative transport protein; hypothetical protein 5258..6625 Escherichia coli APEC O1 5616717 YP_001481362.1 CDS htdV NC_009838.1 6633 7115 D HtdV 6633..7115 Escherichia coli APEC O1 5616718 YP_001481363.1 CDS htdT NC_009838.1 7006 7986 D putative transfer-associated protein; HtdT 7006..7986 Escherichia coli APEC O1 5616719 YP_001481364.1 CDS trhV NC_009838.1 7996 8946 D putative plasmid transfer protein; TrhV 7996..8946 Escherichia coli APEC O1 5616720 YP_001481365.1 CDS trhC NC_009838.1 8955 11636 D putative pilus assembly protein; TrhC 8955..11636 Escherichia coli APEC O1 5616721 YP_001481366.1 CDS parA NC_009838.1 16229 17482 D putative plasmid partitioning protein; hypothetical protein 16229..17482 Escherichia coli APEC O1 5616722 YP_001481367.1 CDS parB NC_009838.1 17479 18483 D putative plasmid partitioning protein; hypothetical protein 17479..18483 Escherichia coli APEC O1 5616723 YP_001481368.1 CDS trhZ NC_009838.1 18545 18934 R TrhZ complement(18545..18934) Escherichia coli APEC O1 5616724 YP_001481369.1 CDS APECO1_O1R15 NC_009838.1 18931 19452 R hypothetical protein complement(18931..19452) Escherichia coli APEC O1 5616725 YP_001481370.1 CDS APECO1_O1R16 NC_009838.1 19445 20281 R hypothetical protein complement(19445..20281) Escherichia coli APEC O1 5616726 YP_001481371.1 CDS trhO NC_009838.1 20278 21225 R TrhO complement(20278..21225) Escherichia coli APEC O1 5616727 YP_001481372.1 CDS parM NC_009838.1 21589 22626 D plasmid partitioning protein; ParM 21589..22626 Escherichia coli APEC O1 5616728 YP_001481373.1 CDS parR NC_009838.1 22638 23276 D plasmid partitioning protein; ParR 22638..23276 Escherichia coli APEC O1 5616729 YP_001481374.1 CDS APECO1_O1R21 NC_009838.1 23624 24604 R putative transposase complement(23624..24604) Escherichia coli APEC O1 5616730 YP_001481375.1 CDS htdA NC_009838.1 24880 25332 D IncHI2 transfer repressor; HtdA 24880..25332 Escherichia coli APEC O1 5616731 YP_001481376.1 CDS htdF NC_009838.1 25322 25747 D putative exported plasmid transfer protein; HtdF 25322..25747 Escherichia coli APEC O1 5616732 YP_001481377.1 CDS hdtK NC_009838.1 25729 26310 D putative plasmid transfer protein 25729..26310 Escherichia coli APEC O1 5616733 YP_001481378.1 CDS APECO1_O1R25 NC_009838.1 26430 30734 D hypothetical protein 26430..30734 Escherichia coli APEC O1 5616734 YP_001481379.1 CDS trhF NC_009838.1 31012 31524 D putative signal peptidase; TrhF 31012..31524 Escherichia coli APEC O1 5616735 YP_001481380.1 CDS trhW NC_009838.1 31511 33022 D putative transfer protein; TrhW 31511..33022 Escherichia coli APEC O1 5616736 YP_001481381.1 CDS trhU NC_009838.1 33062 34222 D putative transfer protein; TrhU 33062..34222 Escherichia coli APEC O1 5616737 YP_001481382.1 CDS trhN NC_009838.1 34241 37429 D putative transfer protein; TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 34241..37429 Escherichia coli APEC O1 5616738 YP_001481383.1 CDS APECO1_O1R30 NC_009838.1 37458 38330 R hypothetical protein complement(37458..38330) Escherichia coli APEC O1 5616739 YP_001481384.1 CDS trhI NC_009838.1 38510 40294 D putative DNA helicase; TrhI 38510..40294 Escherichia coli APEC O1 5616740 YP_001481385.1 CDS APECO1_O1R32 NC_009838.1 40689 41561 D hypothetical protein 40689..41561 Escherichia coli APEC O1 5616741 YP_001481386.1 CDS APECO1_O1R33 NC_009838.1 41619 41996 D hypothetical protein 41619..41996 Escherichia coli APEC O1 5616742 YP_001481387.1 CDS APECO1_O1R34 NC_009838.1 42057 43034 D hypothetical protein 42057..43034 Escherichia coli APEC O1 5616743 YP_001481388.1 CDS APECO1_O1R35 NC_009838.1 43092 44150 D putative ATP-binding protein 43092..44150 Escherichia coli APEC O1 5616744 YP_001481389.1 CDS APECO1_O1R36 NC_009838.1 44519 45646 D hypothetical protein 44519..45646 Escherichia coli APEC O1 5616745 YP_001481390.1 CDS APECO1_O1R37 NC_009838.1 45724 47736 D hypothetical protein 45724..47736 Escherichia coli APEC O1 5616746 YP_001481391.1 CDS APECO1_O1R38 NC_009838.1 47808 48029 D hypothetical protein 47808..48029 Escherichia coli APEC O1 5616747 YP_001481392.1 CDS APECO1_O1R39 NC_009838.1 48071 49375 D hypothetical protein 48071..49375 Escherichia coli APEC O1 5616748 YP_001481393.1 CDS APECO1_O1R40 NC_009838.1 49646 50167 D hypothetical protein 49646..50167 Escherichia coli APEC O1 5616749 YP_001481394.1 CDS APECO1_O1R41 NC_009838.1 50246 51124 D hypothetical protein 50246..51124 Escherichia coli APEC O1 5616750 YP_001481395.1 CDS APECO1_O1R42 NC_009838.1 51195 52130 D hypothetical protein 51195..52130 Escherichia coli APEC O1 5616751 YP_001481396.1 CDS APECO1_O1R43 NC_009838.1 52199 53119 D hypothetical protein 52199..53119 Escherichia coli APEC O1 5616752 YP_001481397.1 CDS APECO1_O1R44 NC_009838.1 53186 54124 D hypothetical protein 53186..54124 Escherichia coli APEC O1 5616753 YP_001481398.1 CDS APECO1_O1R45 NC_009838.1 54290 55252 D hypothetical protein 54290..55252 Escherichia coli APEC O1 5616754 YP_001481399.1 CDS APECO1_O1R46 NC_009838.1 55516 55791 D hypothetical protein 55516..55791 Escherichia coli APEC O1 5616755 YP_001481400.1 CDS APECO1_O1R47 NC_009838.1 55836 56426 D hypothetical protein 55836..56426 Escherichia coli APEC O1 5616756 YP_001481401.1 CDS APECO1_O1R48 NC_009838.1 56434 56691 D hypothetical protein 56434..56691 Escherichia coli APEC O1 5616757 YP_001481402.1 CDS APECO1_O1R49 NC_009838.1 56765 57301 D hypothetical protein 56765..57301 Escherichia coli APEC O1 5616758 YP_001481403.1 CDS APECO1_O1R50 NC_009838.1 57318 57764 D hypothetical protein 57318..57764 Escherichia coli APEC O1 5616759 YP_001481404.1 CDS APECO1_O1R51 NC_009838.1 57837 58817 D putative DNA replication termination protein 57837..58817 Escherichia coli APEC O1 5616760 YP_001481405.1 CDS APECO1_O1R52 NC_009838.1 58827 59732 D hypothetical protein 58827..59732 Escherichia coli APEC O1 5616761 YP_001481406.1 CDS APECO1_O1R53 NC_009838.1 60034 61218 R recombinase complement(60034..61218) Escherichia coli APEC O1 5616762 YP_001481407.1 CDS APECO1_O1R54 NC_009838.1 61953 63035 D hypothetical protein 61953..63035 Escherichia coli APEC O1 5616763 YP_001481408.1 CDS APECO1_O1R55 NC_009838.1 63202 64755 R putative protein kinase complement(63202..64755) Escherichia coli APEC O1 5616764 YP_001481409.1 CDS APECO1_O1R56 NC_009838.1 64727 66364 R hypothetical protein complement(64727..66364) Escherichia coli APEC O1 5616765 YP_001481410.1 CDS terY3 NC_009838.1 66364 67404 R tellurite resistance protein; TerY3 complement(66364..67404) Escherichia coli APEC O1 5616766 YP_001481411.1 CDS terY2 NC_009838.1 67490 68131 R tellurite resistance protein; TerY2 complement(67490..68131) Escherichia coli APEC O1 5616767 YP_001481412.1 CDS terX NC_009838.1 68128 68769 R tellurite resistance protein; TerX complement(68128..68769) Escherichia coli APEC O1 5616768 YP_001481413.1 CDS terY1 NC_009838.1 68792 69511 R tellurite resistance protein; TerY1 complement(68792..69511) Escherichia coli APEC O1 5616769 YP_001481414.1 CDS terW NC_009838.1 69893 70360 R tellurite resistance protein; TerW complement(69893..70360) Escherichia coli APEC O1 5616770 YP_001481415.1 CDS APECO1_O1R62 NC_009838.1 70378 71586 R hypothetical protein complement(70378..71586) Escherichia coli APEC O1 5616771 YP_001481416.1 CDS APECO1_O1R63 NC_009838.1 71597 72553 R hypothetical protein complement(71597..72553) Escherichia coli APEC O1 5616772 YP_001481417.1 CDS APECO1_O1R64 NC_009838.1 72553 73668 R putative ATP-binding protein complement(72553..73668) Escherichia coli APEC O1 5616773 YP_001481418.1 CDS APECO1_O1R65 NC_009838.1 73634 74743 R hypothetical protein complement(73634..74743) Escherichia coli APEC O1 5616774 YP_001481419.1 CDS APECO1_O1R66 NC_009838.1 74400 75542 R hypothetical protein complement(74400..75542) Escherichia coli APEC O1 5616775 YP_001481420.1 CDS APECO1_O1R67 NC_009838.1 75552 76610 R hypothetical protein complement(75552..76610) Escherichia coli APEC O1 5616776 YP_001481421.1 CDS terZ NC_009838.1 76935 77516 D tellurite resistance protein; TerZ 76935..77516 Escherichia coli APEC O1 5616777 YP_001481422.1 CDS terA NC_009838.1 77516 78673 D tellurite resistance protein; TerA 77516..78673 Escherichia coli APEC O1 5616778 YP_001481423.1 CDS terB NC_009838.1 78696 79151 D tellurite resistance protein; TerB 78696..79151 Escherichia coli APEC O1 5616779 YP_001481424.1 CDS terC NC_009838.1 79174 80214 D tellurite resistance protein; TerC 79174..80214 Escherichia coli APEC O1 5616780 YP_001481425.1 CDS terD NC_009838.1 80263 80841 D tellurite resistance protein; TerD 80263..80841 Escherichia coli APEC O1 5616781 YP_001481426.1 CDS terE NC_009838.1 80705 81484 D tellurite resistance protein; TerE 80705..81484 Escherichia coli APEC O1 5616782 YP_001481427.1 CDS terF NC_009838.1 81913 83154 D tellurite resistance protein; TerF 81913..83154 Escherichia coli APEC O1 5616783 YP_001481428.1 CDS APECO1_O1R75 NC_009838.1 84331 84702 R hypothetical protein complement(84331..84702) Escherichia coli APEC O1 5616784 YP_001481429.1 CDS APECO1_O1R76 NC_009838.1 85006 85437 D hypothetical protein 85006..85437 Escherichia coli APEC O1 5616785 YP_001481430.1 CDS APECO1_O1R77 NC_009838.1 85416 85727 D hypothetical protein 85416..85727 Escherichia coli APEC O1 5616709 YP_001481431.1 CDS APECO1_O1R78 NC_009838.1 86038 86334 D hypothetical protein 86038..86334 Escherichia coli APEC O1 5616710 YP_001481432.1 CDS APECO1_O1R79 NC_009838.1 86339 87664 D putative capsule biosynthesis protein 86339..87664 Escherichia coli APEC O1 5616711 YP_001481433.1 CDS tnpA NC_009838.1 87801 88517 D hypothetical protein 87801..88517 Escherichia coli APEC O1 5616786 YP_001481434.1 CDS APECO1_O1R81 NC_009838.1 88575 89078 D hypothetical protein 88575..89078 Escherichia coli APEC O1 5616787 YP_001481435.1 CDS APECO1_O1R82 NC_009838.1 89361 89699 R hypothetical protein complement(89361..89699) Escherichia coli APEC O1 5616788 YP_001481436.1 CDS tetA NC_009838.1 89603 90793 R tetracycline resistance protein; TetA complement(89603..90793) Escherichia coli APEC O1 5616789 YP_001481437.1 CDS tetR NC_009838.1 90886 91545 D tetracycline repressor protein; hypothetical protein 90886..91545 Escherichia coli APEC O1 5616790 YP_001481438.1 CDS tnpA NC_009838.1 91623 94595 R transposase complement(91623..94595) Escherichia coli APEC O1 5616791 YP_001481439.1 CDS tnpR NC_009838.1 94598 95077 R recombinase complement(94598..95077) Escherichia coli APEC O1 5616792 YP_001481440.1 CDS tnpM NC_009838.1 95193 95516 R transposition modulator protein complement(95193..95516) Escherichia coli APEC O1 5616793 YP_001481441.1 CDS intI1 NC_009838.1 95461 96474 R integrase for class 1 integron; IntI1 integrase complement(95461..96474) Escherichia coli APEC O1 5616794 YP_001481442.2 CDS aadA NC_009838.1 96620 97411 D streptomycin/spectinomycin resistance; adenlytransferase; streptomycin 3'-adenyltransferase; aminoglycoside resistance protein 96620..97411 Escherichia coli APEC O1 5616795 YP_001481443.1 CDS aac3-VI NC_009838.1 97575 98477 D gentamicin resistance protein; Aac3-VI 97575..98477 Escherichia coli APEC O1 5616796 YP_001481444.1 CDS groEL NC_009838.1 99060 100697 D chaperonin; heat shock protein; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 99060..100697 Escherichia coli APEC O1 5616797 YP_001481445.1 CDS tnpA NC_009838.1 100886 102415 D transposase 100886..102415 Escherichia coli APEC O1 5616798 YP_001481446.1 CDS APECO1_O1R93 NC_009838.1 101936 103855 R hypothetical protein complement(101936..103855) Escherichia coli APEC O1 5616799 YP_001481447.1 CDS qacEdelta1 NC_009838.1 104136 104483 D quaternary ammonium compound resistance protein 104136..104483 Escherichia coli APEC O1 5616800 YP_001481448.2 CDS sulI NC_009838.1 104477 105316 D sulfonamide resistance; dihydropteroate synthase 104477..105316 Escherichia coli APEC O1 5616801 YP_001481449.1 CDS APECO1_O1R96 NC_009838.1 105530 106255 D hypothetical protein 105530..106255 Escherichia coli APEC O1 5616802 YP_001481450.1 CDS APECO1_O1R96.2 NC_009838.1 106376 107197 R putative transposase complement(106376..107197) Escherichia coli APEC O1 5616803 YP_001481451.1 CDS tnpA NC_009838.1 107507 108580 D putative transposase 107507..108580 Escherichia coli APEC O1 5616804 YP_001481452.1 CDS tnsA NC_009838.1 109164 110006 D Tn7-like transposase; TnsA 109164..110006 Escherichia coli APEC O1 5616805 YP_001481453.1 CDS tnsB NC_009838.1 109993 112116 D Tn7-like transposase; TnsB 109993..112116 Escherichia coli APEC O1 5616806 YP_001481454.1 CDS tnsC NC_009838.1 112116 113564 D Tn7-like transposase; TnsC 112116..113564 Escherichia coli APEC O1 5616807 YP_001481455.1 CDS tnsD NC_009838.1 113596 115161 D Tn7-like transposase; TnsD 113596..115161 Escherichia coli APEC O1 5616808 YP_001481456.1 CDS APECO1_O1R102 NC_009838.1 115173 115841 D hypothetical protein 115173..115841 Escherichia coli APEC O1 5616809 YP_001481457.1 CDS tnpA NC_009838.1 115878 116801 R IS4 transposase complement(115878..116801) Escherichia coli APEC O1 5616810 YP_001481458.1 CDS APECO1_O1R104 NC_009838.1 116826 117164 D hypothetical protein 116826..117164 Escherichia coli APEC O1 5616811 YP_001481459.1 CDS APECO1_O1R105 NC_009838.1 117517 117816 D putative transcriptional regulator 117517..117816 Escherichia coli APEC O1 5616812 YP_001481460.1 CDS APECO1_O1R106 NC_009838.1 118381 120207 D ATP/GTP-binding protein 118381..120207 Escherichia coli APEC O1 5616813 YP_001481461.1 CDS APECO1_O1R107 NC_009838.1 120434 120775 D hypothetical protein 120434..120775 Escherichia coli APEC O1 5616814 YP_001481462.1 CDS silE NC_009838.1 120874 121422 R silver binding protein; silver resistance; SilE complement(120874..121422) Escherichia coli APEC O1 5616815 YP_001481463.1 CDS silS NC_009838.1 121550 123031 R putative sensor kinase; silver resistance; sensor kinase CusS complement(121550..123031) Escherichia coli APEC O1 5616816 YP_001481464.1 CDS silR NC_009838.1 123024 123704 R putative transcriptional regulatory protein; silver resistance; response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(123024..123704) Escherichia coli APEC O1 5616817 YP_001481465.1 CDS silC NC_009838.1 123591 125279 D outer membrane efflux protein; silver resistance; with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 123591..125279 Escherichia coli APEC O1 5616818 YP_001481466.1 CDS APECO1_O1R112 NC_009838.1 125307 125660 D periplasmic copper-binding protein 125307..125660 Escherichia coli APEC O1 5616819 YP_001481467.1 CDS silB NC_009838.1 125774 127066 D silver resistance protein; with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 125774..127066 Escherichia coli APEC O1 5616820 YP_001481468.1 CDS silA NC_009838.1 127077 130223 D cation efflux system protein; silver resistance; SilA 127077..130223 Escherichia coli APEC O1 5616821 YP_001481469.1 CDS APECO1_O1R115 NC_009838.1 130304 130750 D hypothetical protein 130304..130750 Escherichia coli APEC O1 5616822 YP_001481470.1 CDS silP NC_009838.1 130877 133324 D cation-transporting P-type ATPase; silver resistance; SilP 130877..133324 Escherichia coli APEC O1 5616823 YP_001481471.1 CDS APECO1_O1R117 NC_009838.1 133596 134333 R putative peptidase complement(133596..134333) Escherichia coli APEC O1 5616824 YP_001481472.1 CDS pcoE NC_009838.1 134622 135071 R copper resistance protein; PcoE complement(134622..135071) Escherichia coli APEC O1 5616825 YP_001481473.1 CDS pcoA NC_009838.1 135300 137123 D copper resistance protein; PcoA 135300..137123 Escherichia coli APEC O1 5616826 YP_001481474.1 CDS pcoB NC_009838.1 137120 138019 D copper resistance protein; PcoB 137120..138019 Escherichia coli APEC O1 5616827 YP_001481475.1 CDS pcoC NC_009838.1 138059 138439 D copper resistance protein; PcoC 138059..138439 Escherichia coli APEC O1 5616828 YP_001481476.1 CDS pcoD NC_009838.1 138444 139373 D copper resistance protein; PcoD 138444..139373 Escherichia coli APEC O1 5616829 YP_001481477.1 CDS pcoR NC_009838.1 139428 140108 D copper resistance regulatory protein; PcoR 139428..140108 Escherichia coli APEC O1 5616830 YP_001481478.1 CDS pcoS NC_009838.1 140105 141505 D copper resistance sensor kinase; PcoS 140105..141505 Escherichia coli APEC O1 5616831 YP_001481479.1 CDS pcoE NC_009838.1 141723 142157 D copper binding protein; PcoE 141723..142157 Escherichia coli APEC O1 5616832 YP_001481480.1 CDS APECO1_O1R124 NC_009838.1 142523 143353 D hypothetical protein 142523..143353 Escherichia coli APEC O1 5616833 YP_001481481.1 CDS APECO1_O1R125 NC_009838.1 143350 144555 D ATP/GTP-binding protein 143350..144555 Escherichia coli APEC O1 5616834 YP_001481482.1 CDS APECO1_O1R126 NC_009838.1 144835 146154 R hypothetical protein complement(144835..146154) Escherichia coli APEC O1 5616835 YP_001481483.1 CDS APECO1_O1R127 NC_009838.1 146405 147874 R DNA cytosine methylase complement(146405..147874) Escherichia coli APEC O1 5616836 YP_001481484.1 CDS APECO1_O1R128 NC_009838.1 148008 148562 D putative nuclease 148008..148562 Escherichia coli APEC O1 5616837 YP_001481485.1 CDS APECO1_O1R129 NC_009838.1 148481 149461 D hypothetical protein 148481..149461 Escherichia coli APEC O1 5616838 YP_001481486.1 CDS APECO1_O1R130 NC_009838.1 149465 149716 R hypothetical protein complement(149465..149716) Escherichia coli APEC O1 5616839 YP_001481487.1 CDS APECO1_O1R131 NC_009838.1 150782 151081 D hypothetical protein 150782..151081 Escherichia coli APEC O1 5616840 YP_001481488.1 CDS APECO1_O1R132 NC_009838.1 151418 151954 D hypothetical protein 151418..151954 Escherichia coli APEC O1 5616841 YP_001481489.1 CDS APECO1_O1R133 NC_009838.1 152016 152378 D hypothetical protein 152016..152378 Escherichia coli APEC O1 5616842 YP_001481490.1 CDS tnpA NC_009838.1 153315 154031 D IS26 transposase 153315..154031 Escherichia coli APEC O1 5616843 YP_001481491.1 CDS mucA NC_009838.1 154453 154887 D UV protection and repair protein 154453..154887 Escherichia coli APEC O1 5616844 YP_001481492.1 CDS mucB NC_009838.1 154871 156130 D UV protection and repair protein 154871..156130 Escherichia coli APEC O1 5616845 YP_001481493.1 CDS APECO1_O1R137 NC_009838.1 156176 156985 R hypothetical protein complement(156176..156985) Escherichia coli APEC O1 5616846 YP_001481494.1 CDS APECO1_O1R138 NC_009838.1 157092 157703 D hypothetical protein 157092..157703 Escherichia coli APEC O1 5616847 YP_001481495.1 CDS APECO1_O1R139 NC_009838.1 157763 158185 R hypothetical protein complement(157763..158185) Escherichia coli APEC O1 5616848 YP_001481496.1 CDS APECO1_O1R140 NC_009838.1 158219 158617 R hypothetical protein complement(158219..158617) Escherichia coli APEC O1 5616849 YP_001481497.1 CDS dsbC NC_009838.1 158636 159385 R thiol:disulfide interchange protein; DsbC complement(158636..159385) Escherichia coli APEC O1 5616850 YP_001481498.1 CDS APECO1_O1R142 NC_009838.1 159533 160072 D putative pilin biogenesis protein 159533..160072 Escherichia coli APEC O1 5616851 YP_001481499.1 CDS APECO1_O1R143 NC_009838.1 160203 160721 D hypothetical protein 160203..160721 Escherichia coli APEC O1 5616852 YP_001481500.1 CDS APECO1_O1R144 NC_009838.1 160829 162118 R hypothetical protein complement(160829..162118) Escherichia coli APEC O1 5616853 YP_001481501.1 CDS trhG NC_009838.1 162299 166252 R inner membrane protein complement(162299..166252) Escherichia coli APEC O1 5616854 YP_001481502.1 CDS trhH NC_009838.1 166261 167739 R pilus assembly protein complement(166261..167739) Escherichia coli APEC O1 5616855 YP_001481503.1 CDS trhF NC_009838.1 167666 168712 R pilus assembly protein complement(167666..168712) Escherichia coli APEC O1 5616856 YP_001481504.1 CDS trhY NC_009838.1 169306 169818 R plasmid transfer protein complement(169306..169818) Escherichia coli APEC O1 5616857 YP_001481505.1 CDS trhR NC_009838.1 169820 170620 R plasmid transfer protein complement(169820..170620) Escherichia coli APEC O1 5616858 YP_001481506.1 CDS traH NC_009838.1 171379 171864 D plasmid transfer protein 171379..171864 Escherichia coli APEC O1 5616859 YP_001481507.1 CDS APECO1_O1R151 NC_009838.1 171861 172598 D hypothetical protein 171861..172598 Escherichia coli APEC O1 5616860 YP_001481508.1 CDS traI NC_009838.1 172602 175754 D plasmid transfer protein; hypothetical protein 172602..175754 Escherichia coli APEC O1 5616861 YP_001481509.1 CDS traG NC_009838.1 175754 177838 D plasmid transfer protein; hypothetical protein 175754..177838 Escherichia coli APEC O1 5616862 YP_001481510.1 CDS APECO1_O1R154 NC_009838.1 177838 178947 D hypothetical protein 177838..178947 Escherichia coli APEC O1 5616863 YP_001481511.1 CDS traJ NC_009838.1 178916 179596 D plasmid transfer protein; hypothetical protein 178916..179596 Escherichia coli APEC O1 5616864 YP_001481512.1 CDS APECO1_O1R156 NC_009838.1 179607 180788 D hypothetical protein 179607..180788 Escherichia coli APEC O1 5616865 YP_001481513.1 CDS APECO1_O1R157 NC_009838.1 180790 181521 D hypothetical protein 180790..181521 Escherichia coli APEC O1 5616866 YP_001481514.1 CDS APECO1_O1R158 NC_009838.1 181808 182170 R hypothetical protein complement(181808..182170) Escherichia coli APEC O1 5616867 YP_001481515.1 CDS APECO1_O1R159 NC_009838.1 182227 182511 R hypothetical protein complement(182227..182511) Escherichia coli APEC O1 5616868 YP_001481516.1 CDS APECO1_O1R160 NC_009838.1 182868 183170 R hypothetical protein complement(182868..183170) Escherichia coli APEC O1 5616869 YP_001481517.1 CDS APECO1_O1R161 NC_009838.1 183603 183971 R hypothetical protein complement(183603..183971) Escherichia coli APEC O1 5616870 YP_001481518.1 CDS APECO1_O1R162 NC_009838.1 184136 184678 R hypothetical protein complement(184136..184678) Escherichia coli APEC O1 5616871 YP_001481519.1 CDS APECO1_O1R163 NC_009838.1 184740 185177 R hypothetical protein complement(184740..185177) Escherichia coli APEC O1 5616872 YP_001481520.1 CDS APECO1_O1R164 NC_009838.1 185222 185518 R hypothetical protein complement(185222..185518) Escherichia coli APEC O1 5616873 YP_001481521.1 CDS APECO1_O1R165 NC_009838.1 186120 186512 D hypothetical protein 186120..186512 Escherichia coli APEC O1 5616874 YP_001481522.1 CDS APECO1_O1R166 NC_009838.1 186449 187633 R putative DNA binding protein complement(186449..187633) Escherichia coli APEC O1 5616875 YP_001481523.1 CDS APECO1_O1R167 NC_009838.1 187664 188044 D hypothetical protein 187664..188044 Escherichia coli APEC O1 5616876 YP_001481524.1 CDS APECO1_O1R168 NC_009838.1 188049 188279 R hypothetical protein complement(188049..188279) Escherichia coli APEC O1 5616877 YP_001481525.1 CDS APECO1_O1R169 NC_009838.1 188735 189679 D hypothetical protein 188735..189679 Escherichia coli APEC O1 5616878 YP_001481526.1 CDS APECO1_O1R170 NC_009838.1 189776 190378 D hypothetical protein 189776..190378 Escherichia coli APEC O1 5616879 YP_001481527.1 CDS APECO1_O1R171 NC_009838.1 190432 190788 D hypothetical protein 190432..190788 Escherichia coli APEC O1 5616880 YP_001481528.1 CDS APECO1_O1R172 NC_009838.1 191047 191349 R hypothetical protein complement(191047..191349) Escherichia coli APEC O1 5616881 YP_001481529.1 CDS stm NC_009838.1 191456 191671 R plasmid stable inheritance protein; small toxic polypeptide complement(191456..191671) Escherichia coli APEC O1 5616882 YP_001481530.1 CDS APECO1_O1R174 NC_009838.1 191969 192574 R hypothetical protein complement(191969..192574) Escherichia coli APEC O1 5616883 YP_001481531.1 CDS APECO1_O1R175 NC_009838.1 192700 193113 D hypothetical protein 192700..193113 Escherichia coli APEC O1 5616884 YP_001481532.1 CDS APECO1_O1R176 NC_009838.1 193446 193757 R hypothetical protein complement(193446..193757) Escherichia coli APEC O1 5616885 YP_001481533.1 CDS APECO1_O1R177 NC_009838.1 194026 194427 D hypothetical protein 194026..194427 Escherichia coli APEC O1 5616886 YP_001481534.1 CDS APECO1_O1R178 NC_009838.1 195255 195746 R hypothetical protein complement(195255..195746) Escherichia coli APEC O1 5616887 YP_001481535.1 CDS APECO1_O1R179 NC_009838.1 195751 196062 R hypothetical protein complement(195751..196062) Escherichia coli APEC O1 5616888 YP_001481536.1 CDS APECO1_O1R180 NC_009838.1 196578 196898 R hypothetical protein complement(196578..196898) Escherichia coli APEC O1 5616889 YP_001481537.1 CDS APECO1_O1R181 NC_009838.1 197078 197305 R hypothetical protein complement(197078..197305) Escherichia coli APEC O1 5616890 YP_001481538.1 CDS APECO1_O1R182 NC_009838.1 197533 198144 R hypothetical protein complement(197533..198144) Escherichia coli APEC O1 5616891 YP_001481539.1 CDS APECO1_O1R183 NC_009838.1 198256 198822 R hypothetical protein complement(198256..198822) Escherichia coli APEC O1 5616892 YP_001481540.1 CDS APECO1_O1R184 NC_009838.1 199035 199346 R hypothetical protein complement(199035..199346) Escherichia coli APEC O1 5616893 YP_001481541.1 CDS APECO1_O1R185 NC_009838.1 199298 199651 D hypothetical protein 199298..199651 Escherichia coli APEC O1 5616894 YP_001481542.1 CDS APECO1_O1R186 NC_009838.1 199898 202282 R hypothetical protein complement(199898..202282) Escherichia coli APEC O1 5616895 YP_001481543.1 CDS APECO1_O1R187 NC_009838.1 202454 202903 R hypothetical protein complement(202454..202903) Escherichia coli APEC O1 5616896 YP_001481544.1 CDS APECO1_O1R188 NC_009838.1 202955 203746 R hypothetical protein complement(202955..203746) Escherichia coli APEC O1 5616897 YP_001481545.1 CDS APECO1_O1R189 NC_009838.1 204122 205045 R putative transposase complement(204122..205045) Escherichia coli APEC O1 5616898 YP_001481546.1 CDS APECO1_O1R190 NC_009838.1 205146 207218 D hypothetical protein 205146..207218 Escherichia coli APEC O1 5616899 YP_001481547.1 CDS repHI2 NC_009838.1 208326 209414 D RepH12 208326..209414 Escherichia coli APEC O1 5616900 YP_001481548.1 CDS APECO1_O1R192 NC_009838.1 209778 210467 D hypothetical protein 209778..210467 Escherichia coli APEC O1 5616901 YP_001481549.1 CDS APECO1_O1R193 NC_009838.1 211493 213913 R hypothetical protein complement(211493..213913) Escherichia coli APEC O1 5616902 YP_001481550.1 CDS APECO1_O1R194 NC_009838.1 214378 214989 R hypothetical protein complement(214378..214989) Escherichia coli APEC O1 5616903 YP_001481551.1 CDS APECO1_O1R195 NC_009838.1 215010 215273 R hypothetical protein complement(215010..215273) Escherichia coli APEC O1 5616904 YP_001481552.1 CDS APECO1_O1R196 NC_009838.1 215367 216128 R hypothetical protein complement(215367..216128) Escherichia coli APEC O1 5616905 YP_001481553.1 CDS APECO1_O1R197 NC_009838.1 216209 216973 R hypothetical protein complement(216209..216973) Escherichia coli APEC O1 5616906 YP_001481554.1 CDS APECO1_O1R198 NC_009838.1 217303 217818 D hypothetical protein 217303..217818 Escherichia coli APEC O1 5616907 YP_001481555.1 CDS APECO1_O1R199 NC_009838.1 217922 218359 D hypothetical protein 217922..218359 Escherichia coli APEC O1 5616908 YP_001481556.1 CDS APECO1_O1R200 NC_009838.1 218346 218603 D hypothetical protein 218346..218603 Escherichia coli APEC O1 5616909 YP_001481557.1 CDS APECO1_O1R201 NC_009838.1 218811 219062 D hypothetical protein 218811..219062 Escherichia coli APEC O1 5616910 YP_001481558.1 CDS APECO1_O1R202 NC_009838.1 219439 221856 D hypothetical protein 219439..221856 Escherichia coli APEC O1 5616911 YP_001481559.1 CDS APECO1_O1R203 NC_009838.1 222291 222761 D hypothetical protein 222291..222761 Escherichia coli APEC O1 5616912 YP_001481560.1 CDS APECO1_O1R204 NC_009838.1 222811 223107 D putative plasmid maintenance protein 222811..223107 Escherichia coli APEC O1 5616913 YP_001481561.1 CDS APECO1_O1R205 NC_009838.1 223116 224297 D hypothetical protein 223116..224297 Escherichia coli APEC O1 5616914 YP_001481562.1 CDS APECO1_O1R206 NC_009838.1 224705 225082 D hypothetical protein 224705..225082 Escherichia coli APEC O1 5616915 YP_001481563.1 CDS APECO1_O1R207 NC_009838.1 225177 225605 D hypothetical protein 225177..225605 Escherichia coli APEC O1 5616916 YP_001481564.1 CDS APECO1_O1R208 NC_009838.1 225637 226023 R hypothetical protein complement(225637..226023) Escherichia coli APEC O1 5616917 YP_001481565.1 CDS APECO1_O1R209 NC_009838.1 226083 226691 D hypothetical protein 226083..226691 Escherichia coli APEC O1 5616918 YP_001481566.1 CDS APECO1_O1R210 NC_009838.1 226860 228110 D putative DNA methyltransferase 226860..228110 Escherichia coli APEC O1 5616919 YP_001481567.1 CDS APECO1_O1R211 NC_009838.1 228463 228768 R hypothetical protein complement(228463..228768) Escherichia coli APEC O1 5616920 YP_001481568.1 CDS APECO1_O1R212 NC_009838.1 228953 229279 D putative DNA methyltransferase 228953..229279 Escherichia coli APEC O1 5616921 YP_001481569.1 CDS APECO1_O1R213 NC_009838.1 229594 230517 D IS4 transposase 229594..230517 Escherichia coli APEC O1 5616922 YP_001481570.1 CDS APECO1_O1R214 NC_009838.1 230835 232370 R ISEc8 transposase complement(230835..232370) Escherichia coli APEC O1 5616923 YP_001481571.1 CDS APECO1_O1R215 NC_009838.1 232420 232767 R ISEc8 transposase complement(232420..232767) Escherichia coli APEC O1 5616924 YP_001481572.1 CDS APECO1_O1R216 NC_009838.1 232764 233147 R hypothetical protein complement(232764..233147) Escherichia coli APEC O1 5616925 YP_001481573.1 CDS APECO1_O1R217 NC_009838.1 233543 235234 R DNA restriction methylase complement(233543..235234) Escherichia coli APEC O1 5616926 YP_001481574.1 CDS APECO1_O1R218 NC_009838.1 235482 236645 R DNA-binding plasmid partitioning protein complement(235482..236645) Escherichia coli APEC O1 5616927 YP_001481575.1 CDS dam NC_009838.1 237015 237827 D DNA adenine methylase 237015..237827 Escherichia coli APEC O1 5616928 YP_001481576.1 CDS APECO1_O1R220 NC_009838.1 237836 238693 R hypothetical protein complement(237836..238693) Escherichia coli APEC O1 5616929 YP_001481577.1 CDS APECO1_O1R221 NC_009838.1 238925 239641 R hypothetical protein complement(238925..239641) Escherichia coli APEC O1 5616930 YP_001481578.1 CDS APECO1_O1R222 NC_009838.1 239856 240911 R hypothetical protein complement(239856..240911) Escherichia coli APEC O1 5616931 APECO1_t01 tRNA APECO1_t01 NC_008563.1 230127 230200 D tRNA-Glu 230127..230200 Escherichia coli APEC O1 6369680 APECO1_t02 tRNA APECO1_t02 NC_008563.1 230216 230287 D tRNA-Ala 230216..230287 Escherichia coli APEC O1 6369603 APECO1_t03 tRNA APECO1_t03 NC_008563.1 241877 241950 D tRNA-Asp 241877..241950 Escherichia coli APEC O1 6369657 APECO1_t04 tRNA APECO1_t04 NC_008563.1 295044 295116 D tRNA-Thr 295044..295116 Escherichia coli APEC O1 6369681 APECO1_t05 tRNA APECO1_t05 NC_008563.1 570628 570701 D tRNA-Arg 570628..570701 Escherichia coli APEC O1 6369656 APECO1_t06 tRNA APECO1_t06 NC_008563.1 672818 672889 R tRNA-Gln complement(672818..672889) Escherichia coli APEC O1 6369663 APECO1_t07 tRNA APECO1_t07 NC_008563.1 672930 673001 R tRNA-Gln complement(672930..673001) Escherichia coli APEC O1 6369673 APECO1_t08 tRNA APECO1_t08 NC_008563.1 673053 673126 R tRNA-Met complement(673053..673126) Escherichia coli APEC O1 6369641 APECO1_t09 tRNA APECO1_t09 NC_008563.1 673145 673216 R tRNA-Gln complement(673145..673216) Escherichia coli APEC O1 6369642 APECO1_t10 tRNA APECO1_t10 NC_008563.1 673254 673325 R tRNA-Gln complement(673254..673325) Escherichia coli APEC O1 6369653 APECO1_t11 tRNA APECO1_t11 NC_008563.1 673352 673433 R tRNA-Leu complement(673352..673433) Escherichia coli APEC O1 6369654 APECO1_t12 tRNA APECO1_t12 NC_008563.1 673447 673520 R tRNA-Met complement(673447..673520) Escherichia coli APEC O1 6369644 APECO1_t13 tRNA APECO1_t13 NC_008563.1 745882 745954 D tRNA-Lys 745882..745954 Escherichia coli APEC O1 6369627 APECO1_t14 tRNA APECO1_t14 NC_008563.1 745993 746065 D tRNA-Val 745993..746065 Escherichia coli APEC O1 6369651 APECO1_t15 tRNA APECO1_t15 NC_008563.1 746071 746143 D tRNA-Lys 746071..746143 Escherichia coli APEC O1 6369652 APECO1_t16 tRNA APECO1_t16 NC_008563.1 746198 746270 D tRNA-Val 746198..746270 Escherichia coli APEC O1 6369645 APECO1_t17 tRNA APECO1_t17 NC_008563.1 746277 746349 D tRNA-Lys 746277..746349 Escherichia coli APEC O1 6369646 APECO1_t18 tRNA APECO1_t18 NC_008563.1 746401 746473 D tRNA-Lys 746401..746473 Escherichia coli APEC O1 6369639 APECO1_t19 tRNA APECO1_t19 NC_008563.1 746510 746582 D tRNA-Lys 746510..746582 Escherichia coli APEC O1 6369640 APECO1_t20 tRNA APECO1_t20 NC_008563.1 897100 897184 R tRNA-Ser complement(897100..897184) Escherichia coli APEC O1 6369599 APECO1_t21 tRNA APECO1_t21 NC_008563.1 1027917 1028001 R tRNA-Ser complement(1027917..1028001) Escherichia coli APEC O1 6369655 APECO1_t22 tRNA APECO1_t22 NC_008563.1 1079923 1080007 R tRNA-Ser complement(1079923..1080007) Escherichia coli APEC O1 6369606 APECO1_t23 tRNA APECO1_t23 NC_008563.1 1300745 1300826 R tRNA-Tyr complement(1300745..1300826) Escherichia coli APEC O1 6369658 APECO1_t24 tRNA APECO1_t24 NC_008563.1 1300863 1300944 D tRNA-Tyr 1300863..1300944 Escherichia coli APEC O1 6369628 APECO1_t25 tRNA APECO1_t25 NC_008563.1 1343024 1343096 D tRNA-Met 1343024..1343096 Escherichia coli APEC O1 6369664 APECO1_t26 tRNA APECO1_t26 NC_008563.1 1343197 1343270 D tRNA-Arg 1343197..1343270 Escherichia coli APEC O1 6369625 APECO1_t27 tRNA APECO1_t27 NC_008563.1 1483268 1483340 D tRNA-Thr 1483268..1483340 Escherichia coli APEC O1 6369678 APECO1_t28 tRNA APECO1_t28 NC_008563.1 1483347 1483418 D tRNA-Gly 1483347..1483418 Escherichia coli APEC O1 6369621 APECO1_t29 tRNA APECO1_t29 NC_008563.1 1763421 1763494 D tRNA-Val 1763421..1763494 Escherichia coli APEC O1 6369668 APECO1_t30 tRNA APECO1_t30 NC_008563.1 1763502 1763575 D tRNA-Val 1763502..1763575 Escherichia coli APEC O1 6369666 APECO1_t31 tRNA APECO1_t31 NC_008563.1 1996791 1996874 R tRNA-Leu complement(1996791..1996874) Escherichia coli APEC O1 6369665 APECO1_t32 tRNA APECO1_t32 NC_008563.1 1996890 1996960 R tRNA-Cys complement(1996890..1996960) Escherichia coli APEC O1 6369613 APECO1_t33 tRNA APECO1_t33 NC_008563.1 1997018 1997090 R tRNA-Gly complement(1997018..1997090) Escherichia coli APEC O1 6369614 APECO1_t34 tRNA APECO1_t34 NC_008563.1 2074608 2074679 R tRNA-Gly complement(2074608..2074679) Escherichia coli APEC O1 6369679 APECO1_t35 tRNA APECO1_t35 NC_008563.1 2074686 2074758 R tRNA-Thr complement(2074686..2074758) Escherichia coli APEC O1 6369604 APECO1_t36 tRNA APECO1_t36 NC_008563.1 2074842 2074914 R tRNA-Met complement(2074842..2074914) Escherichia coli APEC O1 6369630 APECO1_t37 tRNA APECO1_t37 NC_008563.1 2089479 2089565 R tRNA-Ser complement(2089479..2089565) Escherichia coli APEC O1 6369636 APECO1_t38 tRNA APECO1_t38 NC_008563.1 2090557 2090629 D tRNA-Asn 2090557..2090629 Escherichia coli APEC O1 6369682 APECO1_t39 tRNA APECO1_t39 NC_008563.1 2130451 2130523 R tRNA-Asn complement(2130451..2130523) Escherichia coli APEC O1 6369669 APECO1_t40 tRNA APECO1_t40 NC_008563.1 2132275 2132347 D tRNA-Asn 2132275..2132347 Escherichia coli APEC O1 6369612 APECO1_t41 tRNA APECO1_t41 NC_008563.1 2134684 2134756 D tRNA-Asn 2134684..2134756 Escherichia coli APEC O1 6369671 APECO1_t42 tRNA APECO1_t42 NC_008563.1 2398951 2399024 D tRNA-Pro 2398951..2399024 Escherichia coli APEC O1 6369607 APECO1_t43 tRNA APECO1_t43 NC_008563.1 2569987 2570058 D tRNA-Arg 2569987..2570058 Escherichia coli APEC O1 6369594 APECO1_t44 tRNA APECO1_t44 NC_008563.1 2650502 2650574 R tRNA-Ala complement(2650502..2650574) Escherichia coli APEC O1 6369610 APECO1_t45 tRNA APECO1_t45 NC_008563.1 2650617 2650689 R tRNA-Ala complement(2650617..2650689) Escherichia coli APEC O1 6369631 APECO1_t46 tRNA APECO1_t46 NC_008563.1 2653388 2653460 D tRNA-Val 2653388..2653460 Escherichia coli APEC O1 6369647 APECO1_t47 tRNA APECO1_t47 NC_008563.1 2653508 2653580 D tRNA-Val 2653508..2653580 Escherichia coli APEC O1 6369596 APECO1_t48 tRNA APECO1_t48 NC_008563.1 2653630 2653702 D tRNA-Val 2653630..2653702 Escherichia coli APEC O1 6369649 APECO1_t49 tRNA APECO1_t49 NC_008563.1 2653710 2653782 D tRNA-Lys 2653710..2653782 Escherichia coli APEC O1 6369650 APECO1_t50 tRNA APECO1_t50 NC_008563.1 2764208 2764281 D tRNA-Arg 2764208..2764281 Escherichia coli APEC O1 6369615 APECO1_t51 tRNA APECO1_t51 NC_008563.1 2888571 2888643 R tRNA-Ala complement(2888571..2888643) Escherichia coli APEC O1 6369675 APECO1_t52 tRNA APECO1_t52 NC_008563.1 2888689 2888762 R tRNA-Ile complement(2888689..2888762) Escherichia coli APEC O1 6369592 APECO1_t53 tRNA APECO1_t53 NC_008563.1 2991613 2991686 R tRNA-Arg complement(2991613..2991686) Escherichia coli APEC O1 6369670 APECO1_t54 tRNA APECO1_t54 NC_008563.1 2991753 2991826 R tRNA-Arg complement(2991753..2991826) Escherichia coli APEC O1 6369676 APECO1_t55 tRNA APECO1_t55 NC_008563.1 2991893 2991966 R tRNA-Arg complement(2991893..2991966) Escherichia coli APEC O1 6369677 APECO1_t56 tRNA APECO1_t56 NC_008563.1 2992034 2992107 R tRNA-Arg complement(2992034..2992107) Escherichia coli APEC O1 6369600 APECO1_t57 tRNA APECO1_t57 NC_008563.1 2992114 2992203 R tRNA-Ser complement(2992114..2992203) Escherichia coli APEC O1 6369601 APECO1_t58 tRNA APECO1_t58 NC_008563.1 3116237 3116310 D tRNA-Met 3116237..3116310 Escherichia coli APEC O1 6369661 APECO1_t59 tRNA APECO1_t59 NC_008563.1 3116347 3116420 D tRNA-Met 3116347..3116420 Escherichia coli APEC O1 6369595 APECO1_t60 tRNA APECO1_t60 NC_008563.1 3116457 3116530 D tRNA-Met 3116457..3116530 Escherichia coli APEC O1 6369605 APECO1_t61 tRNA APECO1_t61 NC_008563.1 3194929 3194999 R tRNA-Gly complement(3194929..3194999) Escherichia coli APEC O1 6369674 APECO1_t62 tRNA APECO1_t62 NC_008563.1 3305017 3305089 D tRNA-Phe 3305017..3305089 Escherichia coli APEC O1 6369638 APECO1_t63 tRNA APECO1_t63 NC_008563.1 3516314 3516386 D tRNA-Met 3516314..3516386 Escherichia coli APEC O1 6369672 APECO1_t64 tRNA APECO1_t64 NC_008563.1 3610951 3611024 R tRNA-Met complement(3610951..3611024) Escherichia coli APEC O1 6369609 APECO1_t65 tRNA APECO1_t65 NC_008563.1 3614805 3614888 R tRNA-Leu complement(3614805..3614888) Escherichia coli APEC O1 6369667 APECO1_t66 tRNA APECO1_t66 NC_008563.1 3714286 3714358 R tRNA-Thr complement(3714286..3714358) Escherichia coli APEC O1 6369633 APECO1_t67 tRNA APECO1_t67 NC_008563.1 3717678 3717750 R tRNA-Ala complement(3717678..3717750) Escherichia coli APEC O1 6369660 APECO1_t68 tRNA APECO1_t68 NC_008563.1 3717796 3717869 R tRNA-Ile complement(3717796..3717869) Escherichia coli APEC O1 6369608 APECO1_t1 tRNA APECO1_t1 NC_008563.1 4008672 4008745 R tRNA-Pro complement(4008672..4008745) Escherichia coli APEC O1 11031902 APECO1_t69 tRNA APECO1_t69 NC_008563.1 4134644 4134734 D tRNA-Sec 4134644..4134734 Escherichia coli APEC O1 6369611 APECO1_t70 tRNA APECO1_t70 NC_008563.1 4237100 4237172 D tRNA-Glu 4237100..4237172 Escherichia coli APEC O1 6369662 APECO1_t71 tRNA APECO1_t71 NC_008563.1 4240537 4240610 D tRNA-Asp 4240537..4240610 Escherichia coli APEC O1 6369602 APECO1_t72 tRNA APECO1_t72 NC_008563.1 4240622 4240694 D tRNA-Trp 4240622..4240694 Escherichia coli APEC O1 6369616 APECO1_t73 tRNA APECO1_t73 NC_008563.1 4275166 4275239 D tRNA-Arg 4275166..4275239 Escherichia coli APEC O1 6369659 APECO1_t74 tRNA APECO1_t74 NC_008563.1 4275301 4275373 D tRNA-His 4275301..4275373 Escherichia coli APEC O1 6369618 APECO1_t75 tRNA APECO1_t75 NC_008563.1 4275397 4275480 D tRNA-Leu 4275397..4275480 Escherichia coli APEC O1 6369619 APECO1_t76 tRNA APECO1_t76 NC_008563.1 4275526 4275599 D tRNA-Pro 4275526..4275599 Escherichia coli APEC O1 6369617 APECO1_t77 tRNA APECO1_t77 NC_008563.1 4355486 4355559 D tRNA-Ile 4355486..4355559 Escherichia coli APEC O1 6369593 APECO1_t78 tRNA APECO1_t78 NC_008563.1 4355605 4355677 D tRNA-Ala 4355605..4355677 Escherichia coli APEC O1 6369620 APECO1_t79 tRNA APECO1_t79 NC_008563.1 4490106 4490178 D tRNA-Glu 4490106..4490178 Escherichia coli APEC O1 6369632 APECO1_t80 tRNA APECO1_t80 NC_008563.1 4496969 4497041 D tRNA-Thr 4496969..4497041 Escherichia coli APEC O1 6369597 APECO1_t81 tRNA APECO1_t81 NC_008563.1 4497053 4497134 D tRNA-Tyr 4497053..4497134 Escherichia coli APEC O1 6369622 APECO1_t82 tRNA APECO1_t82 NC_008563.1 4497254 4497325 D tRNA-Gly 4497254..4497325 Escherichia coli APEC O1 6369623 APECO1_t83 tRNA APECO1_t83 NC_008563.1 4497335 4497407 D tRNA-Thr 4497335..4497407 Escherichia coli APEC O1 6369624 APECO1_t84 tRNA APECO1_t84 NC_008563.1 4530293 4530365 D tRNA-Glu 4530293..4530365 Escherichia coli APEC O1 6369648 APECO1_t85 tRNA APECO1_t85 NC_008563.1 4770390 4770462 R tRNA-Phe complement(4770390..4770462) Escherichia coli APEC O1 6369634 APECO1_t86 tRNA APECO1_t86 NC_008563.1 4799896 4799968 D tRNA-Gly 4799896..4799968 Escherichia coli APEC O1 6369643 APECO1_t87 tRNA APECO1_t87 NC_008563.1 4800008 4800080 D tRNA-Gly 4800008..4800080 Escherichia coli APEC O1 6369626 APECO1_t88 tRNA APECO1_t88 NC_008563.1 4800119 4800191 D tRNA-Gly 4800119..4800191 Escherichia coli APEC O1 6369629 APECO1_t89 tRNA APECO1_t89 NC_008563.1 4913060 4913141 D tRNA-Leu 4913060..4913141 Escherichia coli APEC O1 6369591 APECO1_t90 tRNA APECO1_t90 NC_008563.1 5000081 5000164 R tRNA-Leu complement(5000081..5000164) Escherichia coli APEC O1 6369598 APECO1_t91 tRNA APECO1_t91 NC_008563.1 5000202 5000285 R tRNA-Leu complement(5000202..5000285) Escherichia coli APEC O1 6369637 APECO1_t92 tRNA APECO1_t92 NC_008563.1 5000317 5000401 R tRNA-Leu complement(5000317..5000401) Escherichia coli APEC O1 6369635 APECO1_r01 rRNA APECO1_r01 NC_008563.1 228500 230053 D 16S ribosomal RNA 228500..230053 Escherichia coli APEC O1 4924485 APECO1_r02 rRNA APECO1_r02 NC_008563.1 230474 233387 D 23S ribosomal RNA 230474..233387 Escherichia coli APEC O1 4924484 APECO1_r03 rRNA APECO1_r03 NC_008563.1 233482 233605 D 5S ribosomal RNA 233482..233605 Escherichia coli APEC O1 4924483 APECO1_r04 rRNA APECO1_r04 NC_008563.1 2885264 2885387 R 5S ribosomal RNA complement(2885264..2885387) Escherichia coli APEC O1 4924488 APECO1_r05 rRNA APECO1_r05 NC_008563.1 2885478 2888384 R 23S ribosomal RNA complement(2885478..2888384) Escherichia coli APEC O1 4924499 APECO1_r06 rRNA APECO1_r06 NC_008563.1 2888826 2890383 R 16S ribosomal RNA complement(2888826..2890383) Escherichia coli APEC O1 4924493 APECO1_r07 rRNA APECO1_r07 NC_008563.1 3714123 3714245 R 5S ribosomal RNA complement(3714123..3714245) Escherichia coli APEC O1 4924500 APECO1_r08 rRNA APECO1_r08 NC_008563.1 3714368 3714491 R 5S ribosomal RNA complement(3714368..3714491) Escherichia coli APEC O1 4924491 APECO1_r09 rRNA APECO1_r09 NC_008563.1 3714583 3717491 R 23S ribosomal RNA complement(3714583..3717491) Escherichia coli APEC O1 4924497 APECO1_r10 rRNA APECO1_r10 NC_008563.1 3717926 3719479 R 16S ribosomal RNA complement(3717926..3719479) Escherichia coli APEC O1 4924495 APECO1_r11 rRNA APECO1_r11 NC_008563.1 4235473 4237026 D 16S ribosomal RNA 4235473..4237026 Escherichia coli APEC O1 4924489 APECO1_r12 rRNA APECO1_r12 NC_008563.1 4237369 4240274 D 23S ribosomal RNA 4237369..4240274 Escherichia coli APEC O1 4924494 APECO1_r13 rRNA APECO1_r13 NC_008563.1 4240365 4240488 D 5S ribosomal RNA 4240365..4240488 Escherichia coli APEC O1 4924504 APECO1_r14 rRNA APECO1_r14 NC_008563.1 4353875 4355429 D 16S ribosomal RNA 4353875..4355429 Escherichia coli APEC O1 4924496 APECO1_r15 rRNA APECO1_r15 NC_008563.1 4355855 4358763 D 23S ribosomal RNA 4355855..4358763 Escherichia coli APEC O1 4924498 APECO1_r16 rRNA APECO1_r16 NC_008563.1 4358854 4358977 D 5S ribosomal RNA 4358854..4358977 Escherichia coli APEC O1 4924486 APECO1_r17 rRNA APECO1_r17 NC_008563.1 4488381 4489946 D 16S ribosomal RNA 4488381..4489946 Escherichia coli APEC O1 4924492 APECO1_r18 rRNA APECO1_r18 NC_008563.1 4490375 4493292 D 23S ribosomal RNA 4490375..4493292 Escherichia coli APEC O1 4924502 APECO1_r19 rRNA APECO1_r19 NC_008563.1 4493383 4493506 D 5S ribosomal RNA 4493383..4493506 Escherichia coli APEC O1 4924487 APECO1_r20 rRNA APECO1_r20 NC_008563.1 4528665 4530212 D 16S ribosomal RNA 4528665..4530212 Escherichia coli APEC O1 4924503 APECO1_r21 rRNA APECO1_r21 NC_008563.1 4530563 4533475 D 23S ribosomal RNA 4530563..4533475 Escherichia coli APEC O1 4924501 APECO1_r22 rRNA APECO1_r22 NC_008563.1 4533566 4533689 D 5S ribosomal RNA 4533566..4533689 Escherichia coli APEC O1 4924490