-- dump date 20140619_081334 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001723016.1 170018062 6064751 48..1451 1 NC_010468.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1451 dnaA 6064751 dnaA Escherichia coli ATCC 8739 chromosomal replication initiation protein YP_001723016.1 48 D 481805 CDS YP_001723017.1 170018063 6068524 1456..2556 1 NC_010468.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2556 6068524 EcolC_0002 Escherichia coli ATCC 8739 DNA polymerase III subunit beta YP_001723017.1 1456 D 481805 CDS YP_001723018.1 170018064 6068546 2556..3629 1 NC_010468.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3629 recF 6068546 recF Escherichia coli ATCC 8739 recombination protein F YP_001723018.1 2556 D 481805 CDS YP_001723019.1 170018065 6068732 3658..6072 1 NC_010468.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 6072 gyrB 6068732 gyrB Escherichia coli ATCC 8739 DNA gyrase subunit B YP_001723019.1 3658 D 481805 CDS YP_001723020.1 170018066 6064907 6312..6710 1 NC_010468.1 PFAM: protein of unknown function DUF937; KEGG: ssn:SSON_3648 hypothetical protein; hypothetical protein 6710 6064907 EcolC_0005 Escherichia coli ATCC 8739 hypothetical protein YP_001723020.1 6312 D 481805 CDS YP_001723021.1 170018067 6068520 6825..7637 1 NC_010468.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 7637 6068520 EcolC_0006 Escherichia coli ATCC 8739 sugar phosphatase YP_001723021.1 6825 D 481805 CDS YP_001723022.1 170018068 6068556 complement(7683..8339) 1 NC_010468.1 KEGG: sfl:SF3768 putative replicase; hypothetical protein 8339 6068556 EcolC_0007 Escherichia coli ATCC 8739 hypothetical protein YP_001723022.1 7683 R 481805 CDS YP_001723023.1 170018069 6064792 8617..9306 1 NC_010468.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfx:S4002 regulator protein for dgo operon; GntR family transcriptional regulator 9306 6064792 EcolC_0008 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001723023.1 8617 D 481805 CDS YP_001723024.1 170018070 6064694 9303..10181 1 NC_010468.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: ssn:SSON_3644 2-oxo-3-deoxygalactonate kinase; 2-dehydro-3-deoxygalactonokinase 10181 6064694 EcolC_0009 Escherichia coli ATCC 8739 2-dehydro-3-deoxygalactonokinase YP_001723024.1 9303 D 481805 CDS YP_001723025.1 170018071 6066883 10165..10782 1 NC_010468.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 10782 6066883 EcolC_0010 Escherichia coli ATCC 8739 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_001723025.1 10165 D 481805 CDS YP_001723026.1 170018072 6068511 10779..11927 1 NC_010468.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ent:Ent638_0009 mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; galactonate dehydratase 11927 6068511 EcolC_0011 Escherichia coli ATCC 8739 galactonate dehydratase YP_001723026.1 10779 D 481805 CDS YP_001723027.1 170018073 6068536 12047..13339 1 NC_010468.1 TIGRFAM: phosphoglycerate transporter; d-galactonate transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3642 D-galactonate transport; d-galactonate transporter 13339 6068536 EcolC_0012 Escherichia coli ATCC 8739 d-galactonate transporter YP_001723027.1 12047 D 481805 CDS YP_001723028.1 170018074 6068510 complement(13336..14400) 1 NC_010468.1 FAD/NAD(P)-binding domain; putative oxidoreductase 14400 6068510 EcolC_0013 Escherichia coli ATCC 8739 putative oxidoreductase YP_001723028.1 13336 R 481805 CDS YP_001723029.1 170018075 6065084 14501..15715 1 NC_010468.1 KEGG: ssn:SSON_3640 hypothetical protein; hypothetical protein 15715 6065084 EcolC_0014 Escherichia coli ATCC 8739 hypothetical protein YP_001723029.1 14501 D 481805 CDS YP_001723030.1 170018076 6068494 complement(15717..16124) 1 NC_010468.1 PFAM: protein of unknown function DUF1375; KEGG: sfv:SFV_3823 hypothetical protein; hypothetical protein 16124 6068494 EcolC_0015 Escherichia coli ATCC 8739 hypothetical protein YP_001723030.1 15717 R 481805 CDS YP_001723031.1 170018077 6068508 16355..16768 1 NC_010468.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 16768 6068508 EcolC_0016 Escherichia coli ATCC 8739 heat shock protein IbpA YP_001723031.1 16355 D 481805 CDS YP_001723032.1 170018078 6068504 16880..17308 1 NC_010468.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 17308 6068504 EcolC_0017 Escherichia coli ATCC 8739 heat shock chaperone IbpB YP_001723032.1 16880 D 481805 CDS YP_001723033.1 170018079 6068509 17504..19165 1 NC_010468.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: sfx:S3992 putative transport protein; hypothetical protein 19165 6068509 EcolC_0018 Escherichia coli ATCC 8739 hypothetical protein YP_001723033.1 17504 D 481805 CDS YP_001723034.1 170018080 6068544 complement(19162..19878) 1 NC_010468.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sdy:SDY_4170 putative transcriptional regulator; GntR family transcriptional regulator 19878 6068544 EcolC_0019 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001723034.1 19162 R 481805 CDS YP_001723035.1 170018081 6066592 20174..21790 1 NC_010468.1 TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, alpha-glucoside-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: ssn:SSON_3634 phosphotransferase system enzyme IIBC component; PTS system alpha-glucoside-specific transporter subunit IIBC 21790 6066592 EcolC_0020 Escherichia coli ATCC 8739 PTS system alpha-glucoside-specific transporter subunit IIBC YP_001723035.1 20174 D 481805 CDS YP_001723036.1 170018082 6068488 21790..23112 1 NC_010468.1 PFAM: glycoside hydrolase family 4; KEGG: sdy:SDY_4168 putative 6-phospho-beta-glucosidase; glycoside hydrolase family protein 23112 6068488 EcolC_0021 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001723036.1 21790 D 481805 CDS YP_001723037.1 170018083 6068477 23681..24889 1 NC_010468.1 KEGG: sdy:SDY_2598 putative virulence protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; IS605 family transposase OrfB 24889 6068477 EcolC_0023 Escherichia coli ATCC 8739 IS605 family transposase OrfB YP_001723037.1 23681 D 481805 CDS YP_001723038.1 170018084 6068484 25060..25407 1 NC_010468.1 PFAM: protein of unknown function DUF202; KEGG: sdy:SDY_4160 hypothetical protein; isocitrate dehydrogenase 25407 6068484 EcolC_0024 Escherichia coli ATCC 8739 isocitrate dehydrogenase YP_001723038.1 25060 D 481805 CDS YP_001723039.1 170018085 6068486 25397..25759 1 NC_010468.1 KEGG: sbo:SBO_3694 hypothetical protein; hypothetical protein 25759 6068486 EcolC_0025 Escherichia coli ATCC 8739 hypothetical protein YP_001723039.1 25397 D 481805 CDS YP_001723040.1 170018086 6068487 25756..26253 1 NC_010468.1 KEGG: sfv:SFV_3836 putative transcriptional regulator; putative transcriptional regulator 26253 6068487 EcolC_0026 Escherichia coli ATCC 8739 putative transcriptional regulator YP_001723040.1 25756 D 481805 CDS YP_001723041.1 170018087 6068658 complement(26261..27445) 1 NC_010468.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 27445 emrD 6068658 emrD Escherichia coli ATCC 8739 multidrug resistance protein D YP_001723041.1 26261 R 481805 CDS YP_001723042.1 170018088 6068661 28583..30271 1 NC_010468.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sfx:S3978 acetolactate synthase I, valine-sensitive, large subunit; acetolactate synthase catalytic subunit 30271 6068661 EcolC_0028 Escherichia coli ATCC 8739 acetolactate synthase catalytic subunit YP_001723042.1 28583 D 481805 CDS YP_001723043.1 170018089 6068513 30275..30565 1 NC_010468.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 30565 6068513 EcolC_0029 Escherichia coli ATCC 8739 acetolactate synthase 1 regulatory subunit YP_001723043.1 30275 D 481805 CDS YP_001723044.1 170018090 6068475 30640..31230 1 NC_010468.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 31230 6068475 EcolC_0030 Escherichia coli ATCC 8739 DNA-binding transcriptional activator UhpA YP_001723044.1 30640 D 481805 CDS YP_001723045.1 170018091 6068480 31230..32732 1 NC_010468.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 32732 6068480 EcolC_0031 Escherichia coli ATCC 8739 sensory histidine kinase UhpB YP_001723045.1 31230 D 481805 CDS YP_001723046.1 170018092 6068496 32742..34061 1 NC_010468.1 membrane protein regulates uhpT expression; regulatory protein UhpC 34061 6068496 EcolC_0032 Escherichia coli ATCC 8739 regulatory protein UhpC YP_001723046.1 32742 D 481805 CDS YP_001723047.1 170018093 6068519 34199..35590 1 NC_010468.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 35590 uhpT 6068519 uhpT Escherichia coli ATCC 8739 sugar phosphate antiporter YP_001723047.1 34199 D 481805 CDS YP_001723048.1 170018094 6068468 complement(35635..37401) 1 NC_010468.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 37401 6068468 EcolC_0034 Escherichia coli ATCC 8739 cryptic adenine deaminase YP_001723048.1 35635 R 481805 CDS YP_001723049.1 170018095 6068479 37576..38910 1 NC_010468.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfx:S3971 hypothetical protein; xanthine/uracil/vitamin C permease 38910 6068479 EcolC_0035 Escherichia coli ATCC 8739 xanthine/uracil/vitamin C permease YP_001723049.1 37576 D 481805 CDS YP_001723050.1 170018096 6068467 38963..39415 1 NC_010468.1 PFAM: protein of unknown function DUF1198; KEGG: sdy:SDY_4144 hypothetical protein; hypothetical protein 39415 6068467 EcolC_0036 Escherichia coli ATCC 8739 hypothetical protein YP_001723050.1 38963 D 481805 CDS YP_001723051.1 170018097 6068507 39461..40816 1 NC_010468.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 40816 nepI 6068507 nepI Escherichia coli ATCC 8739 ribonucleoside transporter YP_001723051.1 39461 D 481805 CDS YP_001723052.1 170018098 6067597 complement(40857..41150) 1 NC_010468.1 KEGG: sbo:SBO_3710 putative transport protein; putative transport protein 41150 6067597 EcolC_0038 Escherichia coli ATCC 8739 putative transport protein YP_001723052.1 40857 R 481805 CDS YP_001723053.1 170018099 6066370 41372..42190 1 NC_010468.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sdy:SDY_4499 lipoprotein-28; hypothetical protein 42190 6066370 EcolC_0039 Escherichia coli ATCC 8739 hypothetical protein YP_001723053.1 41372 D 481805 CDS YP_001723054.1 170018100 6068448 complement(42194..43117) 1 NC_010468.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sdy:SDY_4498 putative permease transporter; carboxylate/amino acid/amine transporter 43117 6068448 EcolC_0040 Escherichia coli ATCC 8739 carboxylate/amino acid/amine transporter YP_001723054.1 42194 R 481805 CDS YP_001723055.1 170018101 6068462 complement(43228..44412) 1 NC_010468.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_0909 putative transport; sugar efflux transporter 44412 6068462 EcolC_0041 Escherichia coli ATCC 8739 sugar efflux transporter YP_001723055.1 43228 R 481805 CDS YP_001723056.1 170018102 6068457 complement(45542..47875) 1 NC_010468.1 KEGG: stt:t2656 hypothetical protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 protein; TOPRIM domain protein; P4 alpha zinc-binding domain protein; primase P4; SMART: Toprim sub domain protein; P4 family phage/plasmid primase 47875 6068457 EcolC_0043 Escherichia coli ATCC 8739 P4 family phage/plasmid primase YP_001723056.1 45542 R 481805 CDS YP_001723057.1 170018103 6068464 complement(47890..48210) 1 NC_010468.1 KEGG: sbo:SBO_4166 putative protein encoded in prophage; putative prophage protein 48210 6068464 EcolC_0044 Escherichia coli ATCC 8739 putative prophage protein YP_001723057.1 47890 R 481805 CDS YP_001723058.1 170018104 6065092 complement(48346..48801) 1 NC_010468.1 KEGG: stt:t2654 hypothetical protein; hypothetical protein 48801 6065092 EcolC_0045 Escherichia coli ATCC 8739 hypothetical protein YP_001723058.1 48346 R 481805 CDS YP_001723059.1 170018105 6068452 complement(48794..49081) 1 NC_010468.1 KEGG: stt:t2653 hypothetical protein; hypothetical protein 49081 6068452 EcolC_0046 Escherichia coli ATCC 8739 hypothetical protein YP_001723059.1 48794 R 481805 CDS YP_001723060.1 170018106 6068431 complement(49074..49664) 1 NC_010468.1 KEGG: sbo:SBO_4168 putative bacteriophage protein; putative bacteriophage protein 49664 6068431 EcolC_0047 Escherichia coli ATCC 8739 putative bacteriophage protein YP_001723060.1 49074 R 481805 CDS YP_001723061.1 170018107 6068440 complement(49661..49927) 1 NC_010468.1 PFAM: Prophage CP4-57 regulatory; KEGG: sbo:SBO_4169 hypothetical protein; phage transcriptional regulator, AlpA 49927 6068440 EcolC_0048 Escherichia coli ATCC 8739 phage transcriptional regulator, AlpA YP_001723061.1 49661 R 481805 CDS YP_001723062.1 170018108 6068649 50480..51214 1 NC_010468.1 KEGG: sbo:SBO_4170 hypothetical protein; hypothetical protein 51214 6068649 EcolC_0049 Escherichia coli ATCC 8739 hypothetical protein YP_001723062.1 50480 D 481805 CDS YP_001723063.1 170018109 6065350 51214..51456 1 NC_010468.1 PFAM: transcriptional activator Ogr/delta; KEGG: spt:SPA4293 hypothetical protein; transcriptional activator Ogr/delta 51456 6065350 EcolC_0050 Escherichia coli ATCC 8739 transcriptional activator Ogr/delta YP_001723063.1 51214 D 481805 CDS YP_001723064.1 170018110 6068470 51480..52043 1 NC_010468.1 PFAM: polarity suppression protein; KEGG: stt:t2648 hypothetical protein; polarity suppression protein 52043 6068470 EcolC_0051 Escherichia coli ATCC 8739 polarity suppression protein YP_001723064.1 51480 D 481805 CDS YP_001723065.1 170018111 6068439 complement(52323..54089) 1 NC_010468.1 KEGG: sfr:Sfri_0781 kap P-loop domain protein; hypothetical protein 54089 6068439 EcolC_0052 Escherichia coli ATCC 8739 hypothetical protein YP_001723065.1 52323 R 481805 CDS YP_001723066.1 170018112 6068469 complement(54119..55294) 1 NC_010468.1 PFAM: integrase family protein; KEGG: spe:Spro_0108 integrase family protein; integrase family protein 55294 6068469 EcolC_0053 Escherichia coli ATCC 8739 integrase family protein YP_001723066.1 54119 R 481805 CDS YP_001723067.1 170018113 6068449 55844..57226 1 NC_010468.1 may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter 57226 6068449 EcolC_0054 Escherichia coli ATCC 8739 putative transporter YP_001723067.1 55844 D 481805 CDS YP_001723068.1 170018114 6068428 57236..59554 1 NC_010468.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 59554 6068428 EcolC_0055 Escherichia coli ATCC 8739 alpha-xylosidase YP_001723068.1 57236 D 481805 CDS YP_001723069.1 170018115 6068445 complement(59607..61316) 1 NC_010468.1 PFAM: AsmA family protein; KEGG: sfx:S4074 hypothetical protein; AsmA family protein 61316 6068445 EcolC_0056 Escherichia coli ATCC 8739 AsmA family protein YP_001723069.1 59607 R 481805 CDS YP_001723070.1 170018116 6068444 complement(61437..62828) 1 NC_010468.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3751 putative transport protein; uracil-xanthine permease 62828 6068444 EcolC_0057 Escherichia coli ATCC 8739 uracil-xanthine permease YP_001723070.1 61437 R 481805 CDS YP_001723071.1 170018117 6065414 63108..64313 1 NC_010468.1 PFAM: sodium/glutamate symporter; KEGG: sdy:SDY_4085 glutamate transport; sodium/glutamate symporter 64313 6065414 EcolC_0058 Escherichia coli ATCC 8739 sodium/glutamate symporter YP_001723071.1 63108 D 481805 CDS YP_001723072.1 170018118 6065282 complement(64482..66563) 1 NC_010468.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 66563 6065282 EcolC_0059 Escherichia coli ATCC 8739 ATP-dependent DNA helicase RecG YP_001723072.1 64482 R 481805 CDS YP_001723073.1 170018119 6068411 complement(66569..67258) 1 NC_010468.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 67258 6068411 EcolC_0060 Escherichia coli ATCC 8739 tRNA guanosine-2'-O-methyltransferase YP_001723073.1 66569 R 481805 CDS YP_001723074.1 170018120 6068417 complement(67265..69373) 1 NC_010468.1 KEGG: sbo:SBO_3727 (p)ppGpp synthetase II; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 69373 6068417 EcolC_0061 Escherichia coli ATCC 8739 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_001723074.1 67265 R 481805 CDS YP_001723075.1 170018121 6068418 complement(69392..69667) 1 NC_010468.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 69667 rpoZ 6068418 rpoZ Escherichia coli ATCC 8739 DNA-directed RNA polymerase subunit omega YP_001723075.1 69392 R 481805 CDS YP_001723076.1 170018122 6066673 complement(69722..70345) 1 NC_010468.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 70345 gmk 6066673 gmk Escherichia coli ATCC 8739 guanylate kinase YP_001723076.1 69722 R 481805 CDS YP_001723077.1 170018123 6068395 70603..72285 1 NC_010468.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 72285 ligB 6068395 ligB Escherichia coli ATCC 8739 NAD-dependent DNA ligase LigB YP_001723077.1 70603 D 481805 CDS YP_001723078.1 170018124 6068427 complement(72282..72899) 1 NC_010468.1 PFAM: protein of unknown function UPF0126; KEGG: sdy:SDY_4077 hypothetical protein; hypothetical protein 72899 6068427 EcolC_0065 Escherichia coli ATCC 8739 hypothetical protein YP_001723078.1 72282 R 481805 CDS YP_001723079.1 170018125 6068397 complement(73190..74014) 1 NC_010468.1 KEGG: sbo:SBO_3734 DNA-damage-inducible protein; DNA-damage-inducible protein D 74014 dinD 6068397 dinD Escherichia coli ATCC 8739 DNA-damage-inducible protein D YP_001723079.1 73190 R 481805 CDS YP_001723080.1 170018126 6068414 complement(74235..75098) 1 NC_010468.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ssn:SSON_3762 putative alpha helix protein; hypothetical protein 75098 6068414 EcolC_0067 Escherichia coli ATCC 8739 hypothetical protein YP_001723080.1 74235 R 481805 CDS YP_001723081.1 170018127 6068420 75225..75941 1 NC_010468.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 75941 rph 6068420 rph Escherichia coli ATCC 8739 ribonuclease PH YP_001723081.1 75225 D 481805 CDS YP_001723082.1 170018128 6068388 76007..76648 1 NC_010468.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 76648 pyrE 6068388 pyrE Escherichia coli ATCC 8739 orotate phosphoribosyltransferase YP_001723082.1 76007 D 481805 CDS YP_001723083.1 170018129 6068408 complement(76685..77281) 1 NC_010468.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 77281 slmA 6068408 slmA Escherichia coli ATCC 8739 nucleoid occlusion protein YP_001723083.1 76685 R 481805 CDS YP_001723084.1 170018130 6068390 complement(77388..77846) 1 NC_010468.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 77846 dut 6068390 dut Escherichia coli ATCC 8739 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001723084.1 77388 R 481805 CDS YP_001723085.1 170018131 6068386 complement(77824..79044) 1 NC_010468.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 79044 6068386 EcolC_0072 Escherichia coli ATCC 8739 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001723085.1 77824 R 481805 CDS YP_001723086.1 170018132 6068394 79240..79884 1 NC_010468.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 79884 radC 6068394 radC Escherichia coli ATCC 8739 DNA repair protein RadC YP_001723086.1 79240 D 481805 CDS YP_001723087.1 170018133 6068399 80101..80337 1 NC_010468.1 required for 70S ribosome assembly; 50S ribosomal protein L28 80337 rpmB 6068399 rpmB Escherichia coli ATCC 8739 50S ribosomal protein L28 YP_001723087.1 80101 D 481805 CDS YP_001723088.1 170018134 6068407 80358..80525 1 NC_010468.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 80525 rpmG 6068407 rpmG Escherichia coli ATCC 8739 50S ribosomal protein L33 YP_001723088.1 80358 D 481805 CDS YP_001723089.1 170018135 6068403 80623..81432 1 NC_010468.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 81432 6068403 EcolC_0076 Escherichia coli ATCC 8739 formamidopyrimidine-DNA glycosylase YP_001723089.1 80623 D 481805 CDS YP_001723090.1 170018136 6068404 complement(81471..81950) 1 NC_010468.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 81950 coaD 6068404 coaD Escherichia coli ATCC 8739 phosphopantetheine adenylyltransferase YP_001723090.1 81471 R 481805 CDS YP_001723091.1 170018137 6068381 complement(81958..83235) 1 NC_010468.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 83235 6068381 EcolC_0078 Escherichia coli ATCC 8739 3-deoxy-D-manno-octulosonic-acid transferase YP_001723091.1 81958 R 481805 CDS YP_001723092.1 170018138 6068372 83684..84706 1 NC_010468.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: sdy:SDY_4062 lipopolysaccharide core biosynthesis protein; lipopolysaccharide core biosynthesis protein 84706 6068372 EcolC_0079 Escherichia coli ATCC 8739 lipopolysaccharide core biosynthesis protein YP_001723092.1 83684 D 481805 CDS YP_001723093.1 170018139 6068377 84703..85827 1 NC_010468.1 PFAM: glycosyl transferase group 1; KEGG: sdy:SDY_4061 glucosyltransferase I; group 1 glycosyl transferase 85827 6068377 EcolC_0080 Escherichia coli ATCC 8739 group 1 glycosyl transferase YP_001723093.1 84703 D 481805 CDS YP_001723094.1 170018140 6068392 85820..86617 1 NC_010468.1 PFAM: lipopolysaccharide kinase; KEGG: sdy:SDY_4060 putative LPS biosynthesis enzyme; lipopolysaccharide kinase 86617 6068392 EcolC_0081 Escherichia coli ATCC 8739 lipopolysaccharide kinase YP_001723094.1 85820 D 481805 CDS YP_001723095.1 170018141 6068385 86633..87649 1 NC_010468.1 PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3631 UDP-D-galactose:(glucosyl)lipopolysaccharide-alpha-1, 3-D-galactosylt ransferase; lipopolysaccharide 3-alpha-galactosyltransferase 87649 6068385 EcolC_0082 Escherichia coli ATCC 8739 lipopolysaccharide 3-alpha-galactosyltransferase YP_001723095.1 86633 D 481805 CDS YP_001723096.1 170018142 6068355 87666..88661 1 NC_010468.1 PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3630 lipopolysaccharide 1,2-glucosyltransferase; lipopolysaccharide glucosyltransferase I 88661 6068355 EcolC_0083 Escherichia coli ATCC 8739 lipopolysaccharide glucosyltransferase I YP_001723096.1 87666 D 481805 CDS YP_001723097.1 170018143 6068379 88671..89363 1 NC_010468.1 PFAM: lipopolysaccharide core biosynthesis protein; KEGG: sdy:SDY_4057 lipopolysaccharide core biosynthesis protein RfaY; lipopolysaccharide core biosynthesis protein 89363 6068379 EcolC_0084 Escherichia coli ATCC 8739 lipopolysaccharide core biosynthesis protein YP_001723097.1 88671 D 481805 CDS YP_001723098.1 170018144 6068369 89389..90414 1 NC_010468.1 PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: ssn:SSON_3781 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase; lipopolysaccharide glucosyltransferase I 90414 6068369 EcolC_0085 Escherichia coli ATCC 8739 lipopolysaccharide glucosyltransferase I YP_001723098.1 89389 D 481805 CDS YP_001723099.1 170018145 6068410 90499..91482 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_3782 putative beta1,3-glucosyltransferase; glycosyl transferase family protein 91482 6068410 EcolC_0086 Escherichia coli ATCC 8739 glycosyl transferase family protein YP_001723099.1 90499 D 481805 CDS YP_001723100.1 170018146 6068621 91528..92781 1 NC_010468.1 PFAM: O-antigen polymerase; KEGG: ssn:SSON_3783 lipid A-core, surface polymer ligase; O-antigen polymerase 92781 6068621 EcolC_0087 Escherichia coli ATCC 8739 O-antigen polymerase YP_001723100.1 91528 D 481805 CDS YP_001723101.1 170018147 6068382 complement(92851..93822) 1 NC_010468.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: ssn:SSON_3784 heptosyl transferase I; ADP-heptose--LPS heptosyltransferase 93822 6068382 EcolC_0088 Escherichia coli ATCC 8739 ADP-heptose--LPS heptosyltransferase YP_001723101.1 92851 R 481805 CDS YP_001723102.1 170018148 6068622 complement(93826..94872) 1 NC_010468.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 94872 6068622 EcolC_0089 Escherichia coli ATCC 8739 ADP-heptose--LPS heptosyltransferase YP_001723102.1 93826 R 481805 CDS YP_001723103.1 170018149 6068344 complement(94882..95814) 1 NC_010468.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 95814 rfaD 6068344 rfaD Escherichia coli ATCC 8739 ADP-L-glycero-D-manno-heptose-6-epimerase YP_001723103.1 94882 R 481805 CDS YP_001723104.1 170018150 6065061 96028..97224 1 NC_010468.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 97224 6065061 EcolC_0091 Escherichia coli ATCC 8739 2-amino-3-ketobutyrate coenzyme A ligase YP_001723104.1 96028 D 481805 CDS YP_001723105.1 170018151 6068362 97234..98259 1 NC_010468.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 98259 tdh 6068362 tdh Escherichia coli ATCC 8739 L-threonine 3-dehydrogenase YP_001723105.1 97234 D 481805 CDS YP_001723106.1 170018152 6065136 98498..99532 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: sdy:SDY_4048 putative regulator; putative glycosyl transferase 99532 6065136 EcolC_0093 Escherichia coli ATCC 8739 putative glycosyl transferase YP_001723106.1 98498 D 481805 CDS YP_001723107.1 170018153 6068368 complement(99519..100478) 1 NC_010468.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: sfx:S4115 hypothetical protein; hypothetical protein 100478 6068368 EcolC_0094 Escherichia coli ATCC 8739 hypothetical protein YP_001723107.1 99519 R 481805 CDS YP_001723108.2 229597229 6068358 complement(100482..101765) 1 NC_010468.1 PFAM: peptidase M23B; KEGG: ssn:SSON_3792 hypothetical protein; hypothetical protein 101765 6068358 EcolC_0095 Escherichia coli ATCC 8739 hypothetical protein YP_001723108.2 100482 R 481805 CDS YP_001723109.1 170018155 6068354 complement(101775..103319) 1 NC_010468.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 103319 6068354 EcolC_0096 Escherichia coli ATCC 8739 phosphoglyceromutase YP_001723109.1 101775 R 481805 CDS YP_001723110.1 170018156 6068346 103564..103995 1 NC_010468.1 PFAM: Rhodanese domain protein; KEGG: sbo:SBO_3617 hypothetical protein; rhodanese domain-containing protein 103995 6068346 EcolC_0097 Escherichia coli ATCC 8739 rhodanese domain-containing protein YP_001723110.1 103564 D 481805 CDS YP_001723111.1 170018157 6065709 104137..104388 1 NC_010468.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: sdy:SDY_4043 glutaredoxin 3; glutaredoxin 3 104388 6065709 EcolC_0098 Escherichia coli ATCC 8739 glutaredoxin 3 YP_001723111.1 104137 D 481805 CDS YP_001723112.1 170018158 6068651 104451..104918 1 NC_010468.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 104918 6068651 EcolC_0099 Escherichia coli ATCC 8739 preprotein translocase subunit SecB YP_001723112.1 104451 D 481805 CDS YP_001723113.1 170018159 6068343 104918..105937 1 NC_010468.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 105937 gpsA 6068343 gpsA Escherichia coli ATCC 8739 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001723113.1 104918 D 481805 CDS YP_001723114.1 170018160 6066777 106017..106838 1 NC_010468.1 catalyzes the O-acetylation of serine; serine acetyltransferase 106838 cysE 6066777 cysE Escherichia coli ATCC 8739 serine acetyltransferase YP_001723114.1 106017 D 481805 CDS YP_001723115.1 170018161 6066893 complement(106891..107364) 1 NC_010468.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK 107364 6066893 EcolC_0102 Escherichia coli ATCC 8739 putative tRNA/rRNA methyltransferase YibK YP_001723115.1 106891 R 481805 CDS YP_001723116.1 170018162 6068616 complement(107518..108708) 1 NC_010468.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 108708 lldD 6068616 lldD Escherichia coli ATCC 8739 L-lactate dehydrogenase YP_001723116.1 107518 R 481805 CDS YP_001723117.1 170018163 6065420 complement(108705..109481) 1 NC_010468.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 109481 6065420 EcolC_0104 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor LldR YP_001723117.1 108705 R 481805 CDS YP_001723118.1 170018164 6065920 complement(109481..111136) 1 NC_010468.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sbo:SBO_3608 L-lactate permease; L-lactate permease 111136 6065920 EcolC_0105 Escherichia coli ATCC 8739 L-lactate permease YP_001723118.1 109481 R 481805 CDS YP_001723119.1 170018165 6067387 complement(116572..117255) 1 NC_010468.1 KEGG: sfv:SFV_3931 putative inner membrane lipoprotein; putative inner membrane lipoprotein 117255 6067387 EcolC_0108 Escherichia coli ATCC 8739 putative inner membrane lipoprotein YP_001723119.1 116572 R 481805 CDS YP_001723120.1 170018166 6065399 complement(117799..118161) 1 NC_010468.1 KEGG: sbo:SBO_3601 hypothetical protein; hypothetical protein 118161 6065399 EcolC_0109 Escherichia coli ATCC 8739 hypothetical protein YP_001723120.1 117799 R 481805 CDS YP_001723121.1 170018167 6068588 118446..118655 1 NC_010468.1 KEGG: sbo:SBO_3600 putative cytoplasmic protein; putative cytoplasmic protein 118655 6068588 EcolC_0110 Escherichia coli ATCC 8739 putative cytoplasmic protein YP_001723121.1 118446 D 481805 CDS YP_001723122.1 170018168 6068589 complement(118667..119254) 1 NC_010468.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 119254 mtlR 6068589 mtlR Escherichia coli ATCC 8739 mannitol repressor protein YP_001723122.1 118667 R 481805 CDS YP_001723123.1 170018169 6068587 complement(119254..120402) 1 NC_010468.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfv:SFV_3937 mannitol-1-phosphate dehydrogenase; mannitol-1-phosphate 5-dehydrogenase 120402 6068587 EcolC_0112 Escherichia coli ATCC 8739 mannitol-1-phosphate 5-dehydrogenase YP_001723123.1 119254 R 481805 CDS YP_001723124.1 170018170 6068598 complement(120632..122545) 1 NC_010468.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ssn:SSON_3809 PTS system, mannitol-specific enzyme IIABC components; PTS system mannitol-specific transporter subunit IIC 122545 6068598 EcolC_0113 Escherichia coli ATCC 8739 PTS system mannitol-specific transporter subunit IIC YP_001723124.1 120632 R 481805 CDS YP_001723125.1 170018171 6066960 123082..123444 1 NC_010468.1 KEGG: sbo:SBO_3596 hypothetical protein; hypothetical protein 123444 6066960 EcolC_0114 Escherichia coli ATCC 8739 hypothetical protein YP_001723125.1 123082 D 481805 CDS YP_001723126.1 170018172 6065097 123447..124583 1 NC_010468.1 PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_3595 hypothetical protein; secretion protein HlyD family protein 124583 6065097 EcolC_0115 Escherichia coli ATCC 8739 secretion protein HlyD family protein YP_001723126.1 123447 D 481805 CDS YP_001723127.1 170018173 6068558 complement(125043..125480) 1 NC_010468.1 hypothetical protein 125480 6068558 EcolC_0116 Escherichia coli ATCC 8739 hypothetical protein YP_001723127.1 125043 R 481805 CDS YP_001723128.1 170018174 6068563 complement(126187..126648) 1 NC_010468.1 KEGG: sbo:SBO_3594 hypothetical protein; hypothetical protein 126648 6068563 EcolC_0117 Escherichia coli ATCC 8739 hypothetical protein YP_001723128.1 126187 R 481805 CDS YP_001723129.1 170018175 6064646 complement(126660..127598) 1 NC_010468.1 PFAM: RHS protein; KEGG: sbo:SBO_3593 RhsA; RHS protein 127598 6064646 EcolC_0118 Escherichia coli ATCC 8739 RHS protein YP_001723129.1 126660 R 481805 CDS YP_001723130.1 170018176 6068538 complement(127646..128488) 1 NC_010468.1 PFAM: PBS lyase HEAT domain protein repeat-containing protein; KEGG: amr:AM1_4076 hypothetical protein; hypothetical protein 128488 6068538 EcolC_0119 Escherichia coli ATCC 8739 hypothetical protein YP_001723130.1 127646 R 481805 CDS YP_001723131.1 170018177 6068552 complement(128509..132642) 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 132642 6068552 EcolC_0120 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001723131.1 128509 R 481805 CDS YP_001723132.1 170018178 6068582 132870..133478 1 NC_010468.1 PFAM: Glutathione S-transferase domain; KEGG: ssn:SSON_3816 putative S-transferase; putative glutathione S-transferase 133478 6068582 EcolC_0121 Escherichia coli ATCC 8739 putative glutathione S-transferase YP_001723132.1 132870 D 481805 CDS YP_001723133.1 170018179 6068525 133576..134967 1 NC_010468.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 134967 6068525 EcolC_0122 Escherichia coli ATCC 8739 selenocysteine synthase YP_001723133.1 133576 D 481805 CDS YP_001723134.1 170018180 6068371 134964..136808 1 NC_010468.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: ssn:SSON_3818 selenocysteinyl-tRNA-specific translation factor; selenocysteinyl-tRNA-specific translation factor 136808 6068371 EcolC_0123 Escherichia coli ATCC 8739 selenocysteinyl-tRNA-specific translation factor YP_001723134.1 134964 D 481805 CDS YP_001723135.1 170018181 6068432 136998..138149 1 NC_010468.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sbo:SBO_3589 putative oxidoreductase; putative alcohol dehydrogenase 138149 6068432 EcolC_0124 Escherichia coli ATCC 8739 putative alcohol dehydrogenase YP_001723135.1 136998 D 481805 CDS YP_001723136.1 170018182 6068348 138314..139852 1 NC_010468.1 PFAM: Aldehyde Dehydrogenase_; KEGG: sfv:SFV_3945 aldehyde dehydrogenase B; aldehyde dehydrogenase 139852 6068348 EcolC_0125 Escherichia coli ATCC 8739 aldehyde dehydrogenase YP_001723136.1 138314 D 481805 CDS YP_001723137.1 170018183 6068336 140397..140720 1 NC_010468.1 KEGG: sfv:SFV_3947 hypothetical protein; hypothetical protein 140720 6068336 EcolC_0126 Escherichia coli ATCC 8739 hypothetical protein YP_001723137.1 140397 D 481805 CDS YP_001723138.1 170018184 6068337 140726..141862 1 NC_010468.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_3948 hypothetical protein; secretion protein HlyD family protein 141862 6068337 EcolC_0127 Escherichia coli ATCC 8739 secretion protein HlyD family protein YP_001723138.1 140726 D 481805 CDS YP_001723139.1 170018185 6068334 complement(141859..142833) 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0144 transcriptional regulator, LysR family; LysR family transcriptional regulator 142833 6068334 EcolC_0128 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001723139.1 141859 R 481805 CDS YP_001723140.1 170018186 6068340 142957..143697 1 NC_010468.1 PFAM: MltA-interacting MipA family protein; KEGG: sfv:SFV_3952 putative outer membrane protein; MltA-interacting MipA family protein 143697 6068340 EcolC_0129 Escherichia coli ATCC 8739 MltA-interacting MipA family protein YP_001723140.1 142957 D 481805 CDS YP_001723141.1 170018187 6068329 complement(144044..144739) 1 NC_010468.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 144739 sgbE 6068329 sgbE Escherichia coli ATCC 8739 L-ribulose-5-phosphate 4-epimerase YP_001723141.1 144044 R 481805 CDS YP_001723142.1 170018188 6068325 complement(144733..145593) 1 NC_010468.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 145593 6068325 EcolC_0132 Escherichia coli ATCC 8739 putative L-xylulose 5-phosphate 3-epimerase YP_001723142.1 144733 R 481805 CDS YP_001723143.1 170018189 6068331 complement(145586..146248) 1 NC_010468.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 146248 sgbH 6068331 sgbH Escherichia coli ATCC 8739 3-keto-L-gulonate-6-phosphate decarboxylase YP_001723143.1 145586 R 481805 CDS YP_001723144.1 170018190 6068516 complement(146245..147741) 1 NC_010468.1 PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3959 L-xylulose kinase, cryptic; carbohydrate kinase FGGY 147741 6068516 EcolC_0134 Escherichia coli ATCC 8739 carbohydrate kinase FGGY YP_001723144.1 146245 R 481805 CDS YP_001723145.1 170018191 6068360 complement(147745..148731) 1 NC_010468.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sfv:SFV_3960 putative solute-binding transport protein; TRAP dicarboxylate transporter subunit DctP 148731 6068360 EcolC_0135 Escherichia coli ATCC 8739 TRAP dicarboxylate transporter subunit DctP YP_001723145.1 147745 R 481805 CDS YP_001723146.1 170018192 6068319 complement(148744..150021) 1 NC_010468.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sfv:SFV_3961 hypothetical protein; TRAP dicarboxylate transporter subunit DctM 150021 6068319 EcolC_0136 Escherichia coli ATCC 8739 TRAP dicarboxylate transporter subunit DctM YP_001723146.1 148744 R 481805 CDS YP_001723147.1 170018193 6068310 complement(150616..151083) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: cko:CKO_05034 hypothetical protein; hypothetical protein 151083 6068310 EcolC_0138 Escherichia coli ATCC 8739 hypothetical protein YP_001723147.1 150616 R 481805 CDS YP_001723148.1 170018194 6068314 complement(151095..152093) 1 NC_010468.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 152093 6068314 EcolC_0139 Escherichia coli ATCC 8739 2,3-diketo-L-gulonate reductase YP_001723148.1 151095 R 481805 CDS YP_001723149.1 170018195 6068323 152294..153142 1 NC_010468.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sbo:SBO_3582 putative regulator; IclR family transcriptional regulator 153142 6068323 EcolC_0140 Escherichia coli ATCC 8739 IclR family transcriptional regulator YP_001723149.1 152294 D 481805 CDS YP_001723150.1 170018196 6066817 153244..153717 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_3581 hypothetical protein; 4Fe-4S ferredoxin 153717 6066817 EcolC_0141 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001723150.1 153244 D 481805 CDS YP_001723151.1 170018197 6068302 complement(153868..155121) 1 NC_010468.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 155121 avtA 6068302 avtA Escherichia coli ATCC 8739 valine--pyruvate transaminase YP_001723151.1 153868 R 481805 CDS YP_001723152.1 170018198 6068305 complement(155299..157329) 1 NC_010468.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 157329 malS 6068305 malS Escherichia coli ATCC 8739 periplasmic alpha-amylase YP_001723152.1 155299 R 481805 CDS YP_001723153.1 170018199 6068297 157649..158473 1 NC_010468.1 PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2; KEGG: sbo:SBO_3578 putative ATP-binding protein; hypothetical protein 158473 6068297 EcolC_0144 Escherichia coli ATCC 8739 hypothetical protein YP_001723153.1 157649 D 481805 CDS YP_001723154.1 170018200 6068299 complement(158669..159847) 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_3577 putative regulator of xyl operon; AraC family transcriptional regulator 159847 6068299 EcolC_0145 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001723154.1 158669 R 481805 CDS YP_001723155.1 170018201 6068306 complement(159925..161106) 1 NC_010468.1 PFAM: inner-membrane translocator; KEGG: sbo:SBO_3576 putative xylose transport, membrane component; monosaccharide-transporting ATPase 161106 6068306 EcolC_0146 Escherichia coli ATCC 8739 monosaccharide-transporting ATPase YP_001723155.1 159925 R 481805 CDS YP_001723156.1 170018202 6068295 complement(161084..162625) 1 NC_010468.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 162625 6068295 EcolC_0147 Escherichia coli ATCC 8739 xylose transporter ATP-binding subunit YP_001723156.1 161084 R 481805 CDS YP_001723157.1 170018203 6068293 complement(162703..163695) 1 NC_010468.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 163695 xylF 6068293 xylF Escherichia coli ATCC 8739 D-xylose transporter subunit XylF YP_001723157.1 162703 R 481805 CDS YP_001723158.1 170018204 6068285 164061..165383 1 NC_010468.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 165383 6068285 EcolC_0149 Escherichia coli ATCC 8739 xylose isomerase YP_001723158.1 164061 D 481805 CDS YP_001723159.1 170018205 6068286 165455..166909 1 NC_010468.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3976 xylulokinase; xylulokinase 166909 6068286 EcolC_0150 Escherichia coli ATCC 8739 xylulokinase YP_001723159.1 165455 D 481805 CDS YP_001723160.1 170018206 6068278 167078..167419 1 NC_010468.1 PFAM: YiaAB two helix domain protein; KEGG: sbo:SBO_3571 hypothetical protein; hypothetical protein 167419 6068278 EcolC_0151 Escherichia coli ATCC 8739 hypothetical protein YP_001723160.1 167078 D 481805 CDS YP_001723161.1 170018207 6068279 167465..167902 1 NC_010468.1 PFAM: YiaAB two helix domain protein; KEGG: sbo:SBO_3570 hypothetical protein; hypothetical protein 167902 6068279 EcolC_0152 Escherichia coli ATCC 8739 hypothetical protein YP_001723161.1 167465 D 481805 CDS YP_001723162.1 170018208 6068274 complement(167944..168939) 1 NC_010468.1 PFAM: acyltransferase 3; KEGG: sdy:SDY_4340 hypothetical protein; acyltransferase 3 168939 6068274 EcolC_0153 Escherichia coli ATCC 8739 acyltransferase 3 YP_001723162.1 167944 R 481805 CDS YP_001723163.1 170018209 6068270 169114..169413 1 NC_010468.1 KEGG: sbo:SBO_3566 putative lipoprotein; putative lipoprotein 169413 6068270 EcolC_0154 Escherichia coli ATCC 8739 putative lipoprotein YP_001723163.1 169114 D 481805 CDS YP_001723164.1 170018210 6068272 169508..170419 1 NC_010468.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 170419 glyQ 6068272 glyQ Escherichia coli ATCC 8739 glycyl-tRNA synthetase subunit alpha YP_001723164.1 169508 D 481805 CDS YP_001723165.1 170018211 6068269 170429..172498 1 NC_010468.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 172498 glyS 6068269 glyS Escherichia coli ATCC 8739 glycyl-tRNA synthetase subunit beta YP_001723165.1 170429 D 481805 CDS YP_001723166.1 170018212 6068273 complement(172786..173589) 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family; integrase catalytic subunit 173589 6068273 EcolC_0157 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001723166.1 172786 R 481805 CDS YP_001723167.1 170018213 6068266 complement(173637..173921) 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 173921 6068266 EcolC_0158 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001723167.1 173637 R 481805 CDS YP_001723168.1 170018214 6068268 174054..174206 1 NC_010468.1 PFAM: Hok/gef cell toxic protein; KEGG: ssn:SSON_3831 putative membrane permeability altering protein; small toxic polypeptide 174206 6068268 EcolC_0159 Escherichia coli ATCC 8739 small toxic polypeptide YP_001723168.1 174054 D 481805 CDS YP_001723169.1 170018215 6068264 complement(174393..174605) 1 NC_010468.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: cko:CKO_05012 hypothetical protein; major cold shock protein 174605 6068264 EcolC_0160 Escherichia coli ATCC 8739 major cold shock protein YP_001723169.1 174393 R 481805 CDS YP_001723170.1 170018216 6064715 complement(174886..175176) 1 NC_010468.1 SMART: helix-turn-helix domain protein; KEGG: sdy:SDY_4348 hypothetical protein; putative transcriptional regulator 175176 6064715 EcolC_0161 Escherichia coli ATCC 8739 putative transcriptional regulator YP_001723170.1 174886 R 481805 CDS YP_001723171.1 170018217 6068257 175610..176320 1 NC_010468.1 KEGG: sdy:SDY_4349 hypothetical protein; hypothetical protein 176320 6068257 EcolC_0162 Escherichia coli ATCC 8739 hypothetical protein YP_001723171.1 175610 D 481805 CDS YP_001723172.1 170018218 6068261 complement(176370..177344) 1 NC_010468.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sbo:SBO_3555 putative dehydrogenase; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 177344 6068261 EcolC_0163 Escherichia coli ATCC 8739 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_001723172.1 176370 R 481805 CDS YP_001723173.1 170018219 6068253 complement(177448..178107) 1 NC_010468.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: ssn:SSON_3836 putative outer membrane protein; putative outer membrane lipoprotein 178107 6068253 EcolC_0164 Escherichia coli ATCC 8739 putative outer membrane lipoprotein YP_001723173.1 177448 R 481805 CDS YP_001723174.1 170018220 6068262 178260..180593 1 NC_010468.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_3536 biotin sulfoxide reductase; molybdopterin guanine dinucleotide-containing S/N-oxide reductase 180593 6068262 EcolC_0165 Escherichia coli ATCC 8739 molybdopterin guanine dinucleotide-containing S/N-oxide reductase YP_001723174.1 178260 D 481805 CDS YP_001723175.1 170018221 6068288 complement(180562..181002) 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_3840 hypothetical protein; hypothetical protein 181002 6068288 EcolC_0166 Escherichia coli ATCC 8739 hypothetical protein YP_001723175.1 180562 R 481805 CDS YP_001723176.1 170018222 6068283 complement(180999..181562) 1 NC_010468.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 181562 6068283 EcolC_0167 Escherichia coli ATCC 8739 3-methyladenine DNA glycosylase YP_001723176.1 180999 R 481805 CDS YP_001723177.1 170018223 6068281 181720..182418 1 NC_010468.1 KEGG: sbo:SBO_3550 putative lipase; putative lipase 182418 6068281 EcolC_0168 Escherichia coli ATCC 8739 putative lipase YP_001723177.1 181720 D 481805 CDS YP_001723178.1 170018224 6068276 182647..183855 1 NC_010468.1 TIGRFAM: Oxalate/Formate Antiporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_3843 putative resistance protein; oxalate/formate antiporter 183855 6068276 EcolC_0169 Escherichia coli ATCC 8739 oxalate/formate antiporter YP_001723178.1 182647 D 481805 CDS YP_001723179.1 170018225 6068246 184179..185870 1 NC_010468.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 185870 6068246 EcolC_0170 Escherichia coli ATCC 8739 phosphoethanolamine transferase YP_001723179.1 184179 D 481805 CDS YP_001723180.1 170018226 6068251 186949..188556 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: sdy:SDY_4567 dipeptide transport protein; 4-phytase 188556 6068251 EcolC_0171 Escherichia coli ATCC 8739 4-phytase YP_001723180.1 186949 D 481805 CDS YP_001723181.1 170018227 6068238 188864..189883 1 NC_010468.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 189883 6068238 EcolC_0172 Escherichia coli ATCC 8739 dipeptide transporter permease DppB YP_001723181.1 188864 D 481805 CDS YP_001723182.1 170018228 6068240 189893..190795 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_3541 dipeptide transport system permease protein 2; dipeptide transporter 190795 6068240 EcolC_0173 Escherichia coli ATCC 8739 dipeptide transporter YP_001723182.1 189893 D 481805 CDS YP_001723183.1 170018229 6068232 190806..191789 1 NC_010468.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 191789 dppD 6068232 dppD Escherichia coli ATCC 8739 dipeptide transporter ATP-binding subunit YP_001723183.1 190806 D 481805 CDS YP_001723184.1 170018230 6068227 191786..192790 1 NC_010468.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 192790 dppF 6068227 dppF Escherichia coli ATCC 8739 dipeptide transporter ATP-binding subunit YP_001723184.1 191786 D 481805 CDS YP_001723185.1 170018231 6065141 complement(192820..194091) 1 NC_010468.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_3851 putative transporter protein; serine transporter 194091 6065141 EcolC_0176 Escherichia coli ATCC 8739 serine transporter YP_001723185.1 192820 R 481805 CDS YP_001723186.1 170018232 6068226 194567..194674 1 NC_010468.1 KEGG: sfl:SF3572 hypothetical protein; hypothetical protein 194674 6068226 EcolC_0177 Escherichia coli ATCC 8739 hypothetical protein YP_001723186.1 194567 D 481805 CDS YP_001723187.1 170018233 6068230 complement(194761..196440) 1 NC_010468.1 KEGG: sfv:SFV_3549 hypothetical protein; hypothetical protein 196440 6068230 EcolC_0178 Escherichia coli ATCC 8739 hypothetical protein YP_001723187.1 194761 R 481805 CDS YP_001723188.1 170018234 6065781 complement(196437..196628) 1 NC_010468.1 KEGG: sfv:SFV_3550 hypothetical protein; hypothetical protein 196628 6065781 EcolC_0179 Escherichia coli ATCC 8739 hypothetical protein YP_001723188.1 196437 R 481805 CDS YP_001723189.1 170018235 6064809 complement(196625..198184) 1 NC_010468.1 KEGG: ssn:SSON_3854 putative protease; putative protease 198184 6064809 EcolC_0180 Escherichia coli ATCC 8739 putative protease YP_001723189.1 196625 R 481805 CDS YP_001723190.1 170018236 6067658 198469..198657 1 NC_010468.1 KEGG: sbo:SBO_3534 hypothetical protein; hypothetical protein 198657 6067658 EcolC_0182 Escherichia coli ATCC 8739 hypothetical protein YP_001723190.1 198469 D 481805 CDS YP_001723191.1 170018237 6066202 198669..199421 1 NC_010468.1 TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: YhjQ family protein; KEGG: sfx:S4201 hypothetical protein; cell division protein 199421 6066202 EcolC_0183 Escherichia coli ATCC 8739 cell division protein YP_001723191.1 198669 D 481805 CDS YP_001723192.1 170018238 6068580 199418..202036 1 NC_010468.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 202036 bcsA 6068580 bcsA Escherichia coli ATCC 8739 cellulose synthase catalytic subunit YP_001723192.1 199418 D 481805 CDS YP_001723193.1 170018239 6068243 202077..204386 1 NC_010468.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 204386 6068243 EcolC_0185 Escherichia coli ATCC 8739 cellulose synthase regulator protein YP_001723193.1 202077 D 481805 CDS YP_001723194.1 170018240 6068233 204393..205499 1 NC_010468.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 205499 6068233 EcolC_0186 Escherichia coli ATCC 8739 endo-1,4-D-glucanase YP_001723194.1 204393 D 481805 CDS YP_001723195.1 170018241 6065574 205481..208954 1 NC_010468.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 208954 6065574 EcolC_0187 Escherichia coli ATCC 8739 cellulose synthase subunit BcsC YP_001723195.1 205481 D 481805 CDS YP_001723196.1 170018242 6067284 209036..211024 1 NC_010468.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase 211024 6067284 EcolC_0188 Escherichia coli ATCC 8739 putative phosphodiesterase YP_001723196.1 209036 D 481805 CDS YP_001723197.1 170018243 6064418 211207..212493 1 NC_010468.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 212493 6064418 EcolC_0189 Escherichia coli ATCC 8739 C4-dicarboxylate transporter DctA YP_001723197.1 211207 D 481805 CDS YP_001723198.1 170018244 6067333 212714..214210 1 NC_010468.1 PFAM: peptidase M16 domain protein; KEGG: sdy:SDY_4547 hypothetical protein; peptidase M16 domain-containing protein 214210 6067333 EcolC_0190 Escherichia coli ATCC 8739 peptidase M16 domain-containing protein YP_001723198.1 212714 D 481805 CDS YP_001723199.1 170018245 6066478 complement(214306..215235) 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: ssn:SSON_3865 ketodeoxygluconokinase; ribokinase-like domain-containing protein 215235 6066478 EcolC_0191 Escherichia coli ATCC 8739 ribokinase-like domain-containing protein YP_001723199.1 214306 R 481805 CDS YP_001723200.1 170018246 6064461 215467..216234 1 NC_010468.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 216234 6064461 EcolC_0192 Escherichia coli ATCC 8739 EAL domain-containing protein YP_001723200.1 215467 D 481805 CDS YP_001723201.1 170018247 6064494 216289..218364 1 NC_010468.1 PFAM: AsmA family protein; KEGG: sbo:SBO_3523 hypothetical protein; AsmA family protein 218364 6064494 EcolC_0193 Escherichia coli ATCC 8739 AsmA family protein YP_001723201.1 216289 D 481805 CDS YP_001723202.1 170018248 6064473 complement(218546..219868) 1 NC_010468.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3868 putative transport protein; major facilitator superfamily metabolite/H(+) symporter 219868 6064473 EcolC_0194 Escherichia coli ATCC 8739 major facilitator superfamily metabolite/H(+) symporter YP_001723202.1 218546 R 481805 CDS YP_001723203.1 170018249 6064518 complement(220279..221292) 1 NC_010468.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: sbo:SBO_3521 hypothetical protein; ribonuclease 221292 6064518 EcolC_0195 Escherichia coli ATCC 8739 ribonuclease YP_001723203.1 220279 R 481805 CDS YP_001723204.1 170018250 6066127 complement(221341..222312) 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_3567 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 222312 6066127 EcolC_0196 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001723204.1 221341 R 481805 CDS YP_001723205.1 170018251 6065573 222760..223362 1 NC_010468.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: sbo:SBO_3519 putative regulator; two component LuxR family transcriptional regulator 223362 6065573 EcolC_0197 Escherichia coli ATCC 8739 two component LuxR family transcriptional regulator YP_001723205.1 222760 D 481805 CDS YP_001723206.1 170018252 6065304 complement(223413..225062) 1 NC_010468.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 225062 treF 6065304 treF Escherichia coli ATCC 8739 trehalase YP_001723206.1 223413 R 481805 CDS YP_001723207.1 170018253 6064526 225467..226864 1 NC_010468.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: ssn:SSON_3568 putative cytochrome c peroxidase; cytochrome-c peroxidase 226864 6064526 EcolC_0199 Escherichia coli ATCC 8739 cytochrome-c peroxidase YP_001723207.1 225467 D 481805 CDS YP_001723208.1 170018254 6065432 227075..228475 1 NC_010468.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_3516 glutamate decarboxylase isozyme; glutamate decarboxylase 228475 6065432 EcolC_0200 Escherichia coli ATCC 8739 glutamate decarboxylase YP_001723208.1 227075 D 481805 CDS YP_001723209.1 170018255 6065394 228845..229669 1 NC_010468.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 229669 6065394 EcolC_0201 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator GadX YP_001723209.1 228845 D 481805 CDS YP_001723210.1 170018256 6065541 230037..230765 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_3987 putative AraC-type regulatory protein; AraC family transcriptional regulator 230765 6065541 EcolC_0202 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001723210.1 230037 D 481805 CDS YP_001723211.1 170018257 6065313 complement(231128..234241) 1 NC_010468.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sdy:SDY_3537 putative transport system permease protein; hydrophobe/amphiphile efflux-1 (HAE1) family protein 234241 6065313 EcolC_0203 Escherichia coli ATCC 8739 hydrophobe/amphiphile efflux-1 (HAE1) family protein YP_001723211.1 231128 R 481805 CDS YP_001723212.1 170018258 6064464 complement(234266..235423) 1 NC_010468.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 235423 6064464 EcolC_0204 Escherichia coli ATCC 8739 multidrug efflux system protein MdtE YP_001723212.1 234266 R 481805 CDS YP_001723213.1 170018259 6064515 complement(235762..236289) 1 NC_010468.1 KEGG: ssn:SSON_3574 hypothetical protein; LuxR family transcriptional regulator 236289 6064515 EcolC_0205 Escherichia coli ATCC 8739 LuxR family transcriptional regulator YP_001723213.1 235762 R 481805 CDS YP_001723214.1 170018260 6065723 complement(237088..237660) 1 NC_010468.1 KEGG: sbo:SBO_3510 hypothetical protein; acid-resistance membrane protein 237660 6065723 EcolC_0206 Escherichia coli ATCC 8739 acid-resistance membrane protein YP_001723214.1 237088 R 481805 CDS YP_001723215.1 170018261 6065701 237915..238247 1 NC_010468.1 inactive form; acid-resistance protein 238247 6065701 EcolC_0207 Escherichia coli ATCC 8739 acid-resistance protein YP_001723215.1 237915 D 481805 CDS YP_001723216.1 170018262 6065999 238363..238689 1 NC_010468.1 KEGG: sbo:SBO_3508 hypothetical protein; acid-resistance protein 238689 hdeB 6065999 hdeB Escherichia coli ATCC 8739 acid-resistance protein YP_001723216.1 238363 D 481805 CDS YP_001723217.1 170018263 6065823 238753..239400 1 NC_010468.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase 239400 6065823 EcolC_0209 Escherichia coli ATCC 8739 putative Mg(2+) transport ATPase YP_001723217.1 238753 D 481805 CDS YP_001723218.1 170018264 6065555 complement(239442..239972) 1 NC_010468.1 PFAM: regulatory protein LuxR; KEGG: ssn:SSON_3579 hypothetical protein; LuxR family transcriptional regulator 239972 6065555 EcolC_0210 Escherichia coli ATCC 8739 LuxR family transcriptional regulator YP_001723218.1 239442 R 481805 CDS YP_001723219.1 170018265 6066018 complement(240128..240694) 1 NC_010468.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sbo:SBO_3505 Slp; Slp family outer membrane lipoprotein 240694 6066018 EcolC_0211 Escherichia coli ATCC 8739 Slp family outer membrane lipoprotein YP_001723219.1 240128 R 481805 CDS YP_001723220.1 170018266 6066204 complement(240942..242165) 1 NC_010468.1 KEGG: sfv:SFV_3519 hypothetical protein; hypothetical protein 242165 6066204 EcolC_0212 Escherichia coli ATCC 8739 hypothetical protein YP_001723220.1 240942 R 481805 CDS YP_001723221.1 170018267 6066102 complement(242794..243219) 1 NC_010468.1 KEGG: sbo:SBO_3501 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; arsenate reductase 243219 6066102 EcolC_0213 Escherichia coli ATCC 8739 arsenate reductase YP_001723221.1 242794 R 481805 CDS YP_001723222.1 170018268 6066306 complement(243232..244521) 1 NC_010468.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein; arsenical pump membrane protein 244521 6066306 EcolC_0214 Escherichia coli ATCC 8739 arsenical pump membrane protein YP_001723222.1 243232 R 481805 CDS YP_001723223.1 170018269 6066643 complement(244575..244928) 1 NC_010468.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 244928 6066643 EcolC_0215 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor ArsR YP_001723223.1 244575 R 481805 CDS YP_001723224.1 170018270 6066517 complement(245805..247157) 1 NC_010468.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 247157 6066517 EcolC_0216 Escherichia coli ATCC 8739 glutathione reductase YP_001723224.1 245805 R 481805 CDS YP_001723225.1 170018271 6066692 complement(247229..248071) 1 NC_010468.1 PFAM: protein of unknown function DUF519; KEGG: sbo:SBO_3497 hypothetical protein; hypothetical protein 248071 6066692 EcolC_0217 Escherichia coli ATCC 8739 hypothetical protein YP_001723225.1 247229 R 481805 CDS YP_001723226.1 170018272 6066316 248274..250316 1 NC_010468.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: sbo:SBO_3496 oligopeptidase A; oligopeptidase A 250316 6066316 EcolC_0218 Escherichia coli ATCC 8739 oligopeptidase A YP_001723226.1 248274 D 481805 CDS YP_001723227.1 170018273 6066956 250324..251076 1 NC_010468.1 predicted SAM-dependent methyltransferase; putative methyltransferase 251076 6066956 EcolC_0219 Escherichia coli ATCC 8739 putative methyltransferase YP_001723227.1 250324 D 481805 CDS YP_001723228.1 170018274 6066879 complement(251125..252594) 1 NC_010468.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 252594 6066879 EcolC_0220 Escherichia coli ATCC 8739 inner membrane transporter YhiP YP_001723228.1 251125 R 481805 CDS YP_001723229.1 170018275 6067060 complement(252912..253346) 1 NC_010468.1 PFAM: UspA domain protein; KEGG: cko:CKO_04943 hypothetical protein; UspA domain-containing protein 253346 6067060 EcolC_0221 Escherichia coli ATCC 8739 UspA domain-containing protein YP_001723229.1 252912 R 481805 CDS YP_001723230.1 170018276 6066775 253737..254072 1 NC_010468.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 254072 6066775 EcolC_0222 Escherichia coli ATCC 8739 universal stress protein UspB YP_001723230.1 253737 D 481805 CDS YP_001723231.1 170018277 6066098 complement(254317..255816) 1 NC_010468.1 PFAM: phosphate transporter; KEGG: sdy:SDY_3569 low-affinity phosphate transport; phosphate transporter 255816 6066098 EcolC_0223 Escherichia coli ATCC 8739 phosphate transporter YP_001723231.1 254317 R 481805 CDS YP_001723232.1 170018278 6066217 256048..257250 1 NC_010468.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbo:SBO_3490 hypothetical protein; hypothetical protein 257250 6066217 EcolC_0224 Escherichia coli ATCC 8739 hypothetical protein YP_001723232.1 256048 D 481805 CDS YP_001723233.1 170018279 6067195 complement(257566..258618) 1 NC_010468.1 KEGG: sbo:SBO_3489 hypothetical protein; hypothetical protein 258618 6067195 EcolC_0225 Escherichia coli ATCC 8739 hypothetical protein YP_001723233.1 257566 R 481805 CDS YP_001723234.1 170018280 6064538 259001..260608 1 NC_010468.1 KEGG: sfl:SF3505 hypothetical protein; hypothetical protein 260608 6064538 EcolC_0226 Escherichia coli ATCC 8739 hypothetical protein YP_001723234.1 259001 D 481805 CDS YP_001723235.1 170018281 6065186 260870..262492 1 NC_010468.1 KEGG: ssn:SSON_3724 hypothetical protein; hypothetical protein 262492 6065186 EcolC_0227 Escherichia coli ATCC 8739 hypothetical protein YP_001723235.1 260870 D 481805 CDS YP_001723236.1 170018282 6064544 262858..263925 1 NC_010468.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_3488 hypothetical protein; secretion protein HlyD family protein 263925 6064544 EcolC_0228 Escherichia coli ATCC 8739 secretion protein HlyD family protein YP_001723236.1 262858 D 481805 CDS YP_001723237.1 170018283 6064543 263922..266657 1 NC_010468.1 PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; KEGG: sfx:S4261 putative ATP-binding component of a transport system; ABC transporter-like protein 266657 6064543 EcolC_0229 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001723237.1 263922 D 481805 CDS YP_001723238.1 170018284 6067133 266657..267781 1 NC_010468.1 PFAM: ABC-2 type transporter; KEGG: sbo:SBO_3480 putative transporter; ABC-2 type transporter 267781 6067133 EcolC_0230 Escherichia coli ATCC 8739 ABC-2 type transporter YP_001723238.1 266657 D 481805 CDS YP_001723239.1 170018285 6067762 complement(269678..270046) 1 NC_010468.1 hypothetical protein 270046 6067762 EcolC_0233 Escherichia coli ATCC 8739 hypothetical protein YP_001723239.1 269678 R 481805 CDS YP_001723240.1 170018286 6067783 complement(270033..274268) 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 274268 6067783 EcolC_0234 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001723240.1 270033 R 481805 CDS YP_001723241.1 170018287 6067809 complement(274471..274872) 1 NC_010468.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 274872 6067809 EcolC_0235 Escherichia coli ATCC 8739 nickel responsive regulator YP_001723241.1 274471 R 481805 CDS YP_001723242.1 170018288 6067803 complement(274878..275684) 1 NC_010468.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 275684 nikE 6067803 nikE Escherichia coli ATCC 8739 nickel transporter ATP-binding protein NikE YP_001723242.1 274878 R 481805 CDS YP_001723243.1 170018289 6067812 complement(275681..276445) 1 NC_010468.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 276445 nikD 6067812 nikD Escherichia coli ATCC 8739 nickel transporter ATP-binding protein NikD YP_001723243.1 275681 R 481805 CDS YP_001723244.1 170018290 6067790 complement(276445..277278) 1 NC_010468.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 277278 nikC 6067790 nikC Escherichia coli ATCC 8739 nickel transporter permease NikC YP_001723244.1 276445 R 481805 CDS YP_001723245.1 170018291 6067826 complement(277275..278219) 1 NC_010468.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 278219 6067826 EcolC_0239 Escherichia coli ATCC 8739 nickel transporter permease NikB YP_001723245.1 277275 R 481805 CDS YP_001723246.1 170018292 6067824 complement(278219..279793) 1 NC_010468.1 KEGG: sfx:S4269 periplasmic binding protein for nickel; TIGRFAM: nickel ABC transporter, periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5; nickel ABC transporter substrate-binding protein 279793 6067824 EcolC_0240 Escherichia coli ATCC 8739 nickel ABC transporter substrate-binding protein YP_001723246.1 278219 R 481805 CDS YP_001723247.1 170018293 6067832 complement(279904..280491) 1 NC_010468.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sbo:SBO_3472 hypothetical protein; holo-(acyl carrier protein) synthase 2 280491 6067832 EcolC_0241 Escherichia coli ATCC 8739 holo-(acyl carrier protein) synthase 2 YP_001723247.1 279904 R 481805 CDS YP_001723248.1 170018294 6067818 complement(280546..281595) 1 NC_010468.1 PFAM: protein of unknown function UPF0118; KEGG: ssn:SSON_3712 hypothetical protein; hypothetical protein 281595 6067818 EcolC_0242 Escherichia coli ATCC 8739 hypothetical protein YP_001723248.1 280546 R 481805 CDS YP_001723249.1 170018295 6067757 281685..282944 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S4272 hypothetical protein; major facilitator superfamily transporter 282944 6067757 EcolC_0243 Escherichia coli ATCC 8739 major facilitator superfamily transporter YP_001723249.1 281685 D 481805 CDS YP_001723250.1 170018296 6067775 complement(282948..283505) 1 NC_010468.1 KEGG: sdy:SDY_3623 hypothetical protein; hypothetical protein 283505 6067775 EcolC_0244 Escherichia coli ATCC 8739 hypothetical protein YP_001723250.1 282948 R 481805 CDS YP_001723251.1 170018297 6067845 complement(283578..284243) 1 NC_010468.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: sfx:S4274 hypothetical protein; hypothetical protein 284243 6067845 EcolC_0245 Escherichia coli ATCC 8739 hypothetical protein YP_001723251.1 283578 R 481805 CDS YP_001723252.1 170018298 6067838 284464..284709 1 NC_010468.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 284709 6067838 EcolC_0246 Escherichia coli ATCC 8739 sulfur transfer protein SirA YP_001723252.1 284464 D 481805 CDS YP_001723253.1 170018299 6067856 complement(284811..287009) 1 NC_010468.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 287009 zntA 6067856 zntA Escherichia coli ATCC 8739 zinc/cadmium/mercury/lead-transporting ATPase YP_001723253.1 284811 R 481805 CDS YP_001723254.1 170018300 6067847 complement(287083..287709) 1 NC_010468.1 PFAM: YhhN family protein; KEGG: sfx:S4277 putative enzyme; hypothetical protein 287709 6067847 EcolC_0248 Escherichia coli ATCC 8739 hypothetical protein YP_001723254.1 287083 R 481805 CDS YP_001723255.1 170018301 6067835 287850..288209 1 NC_010468.1 KEGG: sbo:SBO_3464 putative receptor; putative receptor 288209 6067835 EcolC_0249 Escherichia coli ATCC 8739 putative receptor YP_001723255.1 287850 D 481805 CDS YP_001723256.1 170018302 6067859 complement(288212..288481) 1 NC_010468.1 PFAM: protein of unknown function DUF1145; KEGG: sdy:SDY_3617 hypothetical protein; hypothetical protein 288481 6067859 EcolC_0250 Escherichia coli ATCC 8739 hypothetical protein YP_001723256.1 288212 R 481805 CDS YP_001723257.1 170018303 6067892 complement(288471..289067) 1 NC_010468.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 289067 rsmD 6067892 rsmD Escherichia coli ATCC 8739 16S rRNA m(2)G966-methyltransferase YP_001723257.1 288471 R 481805 CDS YP_001723258.1 170018304 6067884 289217..290713 1 NC_010468.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 290713 6067884 EcolC_0252 Escherichia coli ATCC 8739 cell division protein FtsY YP_001723258.1 289217 D 481805 CDS YP_001723259.1 170018305 6067904 290716..291384 1 NC_010468.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 291384 6067904 EcolC_0253 Escherichia coli ATCC 8739 cell division protein FtsE YP_001723259.1 290716 D 481805 CDS YP_001723260.1 170018306 6067944 291377..292435 1 NC_010468.1 putative ABC transporter, membrane protein; cell division protein FtsX 292435 ftsX 6067944 ftsX Escherichia coli ATCC 8739 cell division protein FtsX YP_001723260.1 291377 D 481805 CDS YP_001723261.1 170018307 6067925 292680..293534 1 NC_010468.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 293534 6067925 EcolC_0255 Escherichia coli ATCC 8739 RNA polymerase factor sigma-32 YP_001723261.1 292680 D 481805 CDS YP_001723262.1 170018308 6067961 293805..294908 1 NC_010468.1 PFAM: Extracellular ligand-binding receptor; KEGG: sbo:SBO_3457 high-affinity amino acid transport system periplasmic binding protein; extracellular ligand-binding receptor 294908 6067961 EcolC_0256 Escherichia coli ATCC 8739 extracellular ligand-binding receptor YP_001723262.1 293805 D 481805 CDS YP_001723263.1 170018309 6067911 complement(295107..295490) 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_3456 hypothetical protein; N-acetyltransferase GCN5 295490 6067911 EcolC_0257 Escherichia coli ATCC 8739 N-acetyltransferase GCN5 YP_001723263.1 295107 R 481805 CDS YP_001723264.1 170018310 6067977 295914..297023 1 NC_010468.1 PFAM: Extracellular ligand-binding receptor; KEGG: sbo:SBO_3453 high-affinity leucine-specific transport system periplasmic binding protein; extracellular ligand-binding receptor 297023 6067977 EcolC_0258 Escherichia coli ATCC 8739 extracellular ligand-binding receptor YP_001723264.1 295914 D 481805 CDS YP_001723265.1 170018311 6067967 297071..297997 1 NC_010468.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease LivH 297997 6067967 EcolC_0259 Escherichia coli ATCC 8739 branched-chain amino acid transporter permease LivH YP_001723265.1 297071 D 481805 CDS YP_001723266.1 170018312 6067992 297994..299271 1 NC_010468.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease 299271 livM 6067992 livM Escherichia coli ATCC 8739 leucine/isoleucine/valine transporter permease YP_001723266.1 297994 D 481805 CDS YP_001723267.1 170018313 6067964 299268..300035 1 NC_010468.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 300035 livG 6067964 livG Escherichia coli ATCC 8739 leucine/isoleucine/valine transporter ATP-binding subunit YP_001723267.1 299268 D 481805 CDS YP_001723268.1 170018314 6067868 300037..300750 1 NC_010468.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 300750 livF 6067868 livF Escherichia coli ATCC 8739 leucine/isoleucine/valine transporter ATP-binding subunit YP_001723268.1 300037 D 481805 CDS YP_001723269.1 170018315 6067899 301147..302463 1 NC_010468.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 302463 6067899 EcolC_0263 Escherichia coli ATCC 8739 glycerol-3-phosphate transporter periplasmic binding protein YP_001723269.1 301147 D 481805 CDS YP_001723270.1 170018316 6068012 302561..303448 1 NC_010468.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 303448 6068012 EcolC_0264 Escherichia coli ATCC 8739 glycerol-3-phosphate transporter permease YP_001723270.1 302561 D 481805 CDS YP_001723271.1 170018317 6068009 303445..304290 1 NC_010468.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 304290 6068009 EcolC_0265 Escherichia coli ATCC 8739 glycerol-3-phosphate transporter membrane protein YP_001723271.1 303445 D 481805 CDS YP_001723272.1 170018318 6068034 304292..305362 1 NC_010468.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 305362 ugpC 6068034 ugpC Escherichia coli ATCC 8739 glycerol-3-phosphate transporter ATP-binding subunit YP_001723272.1 304292 D 481805 CDS YP_001723273.1 170018319 6068030 305359..306102 1 NC_010468.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 306102 ugpQ 6068030 ugpQ Escherichia coli ATCC 8739 glycerophosphodiester phosphodiesterase YP_001723273.1 305359 D 481805 CDS YP_001723274.1 170018320 6068002 complement(306089..306529) 1 NC_010468.1 KEGG: sbo:SBO_3444 hypothetical protein; hypothetical protein 306529 6068002 EcolC_0268 Escherichia coli ATCC 8739 hypothetical protein YP_001723274.1 306089 R 481805 CDS YP_001723275.1 170018321 6066366 306649..308391 1 NC_010468.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 308391 ggt 6066366 ggt Escherichia coli ATCC 8739 gamma-glutamyltranspeptidase YP_001723275.1 306649 D 481805 CDS YP_001723276.1 170018322 6068042 join(309253..309507,309507..309950) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein; insertion element protein 309950 6068042 EcolC_0270 Escherichia coli ATCC 8739 insertion element protein YP_001723276.1 309253 D 481805 CDS YP_001723277.1 170018323 6068066 complement(310533..311021) 1 NC_010468.1 YhhY; regulated by the fur regulator; unknown function; putative acetyltransferase YhhY 311021 6068066 EcolC_0272 Escherichia coli ATCC 8739 putative acetyltransferase YhhY YP_001723277.1 310533 R 481805 CDS YP_001723278.1 170018324 6065741 311354..312391 1 NC_010468.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ssn:SSON_3682 putative regulator; putative dehydrogenase 312391 6065741 EcolC_0273 Escherichia coli ATCC 8739 putative dehydrogenase YP_001723278.1 311354 D 481805 CDS YP_001723279.1 170018325 6065872 312514..313209 1 NC_010468.1 PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: sbo:SBO_3436 hypothetical protein; pirin domain-containing protein 313209 6065872 EcolC_0274 Escherichia coli ATCC 8739 pirin domain-containing protein YP_001723279.1 312514 D 481805 CDS YP_001723280.1 170018326 6066444 313433..314428 1 NC_010468.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cko:CKO_04857 hypothetical protein; LacI family transcriptional regulator 314428 6066444 EcolC_0275 Escherichia coli ATCC 8739 LacI family transcriptional regulator YP_001723280.1 313433 D 481805 CDS YP_001723281.1 170018327 6066791 314606..315094 1 NC_010468.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 315094 gntK 6066791 gntK Escherichia coli ATCC 8739 gluconate kinase YP_001723281.1 314606 D 481805 CDS YP_001723282.1 170018328 6064647 315098..316438 1 NC_010468.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: sdy:SDY_3587 H+/gluconate symporter; low affinity gluconate transporter 316438 6064647 EcolC_0277 Escherichia coli ATCC 8739 low affinity gluconate transporter YP_001723282.1 315098 D 481805 CDS YP_001723283.1 170018329 6065227 complement(316495..317088) 1 NC_010468.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 317088 6065227 EcolC_0278 Escherichia coli ATCC 8739 putative dITP- and XTP- hydrolase YP_001723283.1 316495 R 481805 CDS YP_001723284.1 170018330 6065307 317280..318383 1 NC_010468.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 318383 6065307 EcolC_0279 Escherichia coli ATCC 8739 aspartate-semialdehyde dehydrogenase YP_001723284.1 317280 D 481805 CDS YP_001723285.1 170018331 6065656 318656..320842 1 NC_010468.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 320842 6065656 EcolC_0280 Escherichia coli ATCC 8739 glycogen branching protein YP_001723285.1 318656 D 481805 CDS YP_001723286.1 170018332 6065822 320839..322812 1 NC_010468.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 322812 6065822 EcolC_0281 Escherichia coli ATCC 8739 glycogen debranching protein YP_001723286.1 320839 D 481805 CDS YP_001723287.1 170018333 6066105 322830..324125 1 NC_010468.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 324125 glgC 6066105 glgC Escherichia coli ATCC 8739 glucose-1-phosphate adenylyltransferase YP_001723287.1 322830 D 481805 CDS YP_001723288.1 170018334 6066262 324125..325558 1 NC_010468.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 325558 glgA 6066262 glgA Escherichia coli ATCC 8739 glycogen synthase YP_001723288.1 324125 D 481805 CDS YP_001723289.1 170018335 6066846 325577..328024 1 NC_010468.1 KEGG: sdy:SDY_3574 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; glycogen/starch/alpha-glucan phosphorylase 328024 6066846 EcolC_0284 Escherichia coli ATCC 8739 glycogen/starch/alpha-glucan phosphorylase YP_001723289.1 325577 D 481805 CDS YP_001723290.1 170018336 6067044 328140..329657 1 NC_010468.1 KEGG: ssn:SSON_3666 hypothetical membrane protein; hypothetical protein 329657 6067044 EcolC_0285 Escherichia coli ATCC 8739 hypothetical protein YP_001723290.1 328140 D 481805 CDS YP_001723291.1 170018337 6067696 329683..330675 1 NC_010468.1 KEGG: ssn:SSON_3666 hypothetical membrane protein; hypothetical protein 330675 6067696 EcolC_0286 Escherichia coli ATCC 8739 hypothetical protein YP_001723291.1 329683 D 481805 CDS YP_001723292.1 170018338 6064696 330675..331277 1 NC_010468.1 KEGG: sdy:SDY_3648 hypothetical protein; hypothetical protein 331277 6064696 EcolC_0287 Escherichia coli ATCC 8739 hypothetical protein YP_001723292.1 330675 D 481805 CDS YP_001723293.1 170018339 6064704 complement(331493..332998) 1 NC_010468.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 332998 glpD 6064704 glpD Escherichia coli ATCC 8739 glycerol-3-phosphate dehydrogenase YP_001723293.1 331493 R 481805 CDS YP_001723294.1 170018340 6065106 333188..333514 1 NC_010468.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 333514 glpE 6065106 glpE Escherichia coli ATCC 8739 thiosulfate sulfurtransferase YP_001723294.1 333188 D 481805 CDS YP_001723295.1 170018341 6065483 333559..334389 1 NC_010468.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 334389 6065483 EcolC_0290 Escherichia coli ATCC 8739 intramembrane serine protease GlpG YP_001723295.1 333559 D 481805 CDS YP_001723296.1 170018342 6065820 334406..335164 1 NC_010468.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 335164 6065820 EcolC_0291 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor GlpR YP_001723296.1 334406 D 481805 CDS YP_001723297.1 170018343 6066844 complement(335146..336744) 1 NC_010468.1 PFAM: sigma-54 factor interaction domain-containing protein; regulator of RNA terminal phosphate cyclase; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sfv:SFV_3429 putative 2-component regulator; regulator of RNA terminal phosphate cyclase 336744 6066844 EcolC_0292 Escherichia coli ATCC 8739 regulator of RNA terminal phosphate cyclase YP_001723297.1 335146 R 481805 CDS YP_001723298.1 170018344 6067522 336932..338158 1 NC_010468.1 PFAM: protein of unknown function UPF0027; KEGG: sfv:SFV_3428 hypothetical protein; hypothetical protein 338158 6067522 EcolC_0293 Escherichia coli ATCC 8739 hypothetical protein YP_001723298.1 336932 D 481805 CDS YP_001723299.1 170018345 6067601 338162..339178 1 NC_010468.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 339178 6067601 EcolC_0294 Escherichia coli ATCC 8739 RNA 3'-terminal-phosphate cyclase YP_001723299.1 338162 D 481805 CDS YP_001723300.1 170018346 6064393 complement(339221..341926) 1 NC_010468.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 341926 6064393 EcolC_0295 Escherichia coli ATCC 8739 transcriptional regulator MalT YP_001723300.1 339221 R 481805 CDS YP_001723301.1 170018347 6065748 342538..344931 1 NC_010468.1 KEGG: ssn:SSON_3549 maltodextrin phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; glycogen/starch/alpha-glucan phosphorylase 344931 6065748 EcolC_0296 Escherichia coli ATCC 8739 glycogen/starch/alpha-glucan phosphorylase YP_001723301.1 342538 D 481805 CDS YP_001723302.1 170018348 6064621 344941..347025 1 NC_010468.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 347025 malQ 6064621 malQ Escherichia coli ATCC 8739 4-alpha-glucanotransferase YP_001723302.1 344941 D 481805 CDS YP_001723303.1 170018349 6067888 complement(347070..348386) 1 NC_010468.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: sbo:SBO_3404 high-affinity transport of gluconate/gluconate permease; gluconate transporter 348386 6067888 EcolC_0298 Escherichia coli ATCC 8739 gluconate transporter YP_001723303.1 347070 R 481805 CDS YP_001723304.1 170018350 6067894 complement(348747..349322) 1 NC_010468.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 349322 6067894 EcolC_0299 Escherichia coli ATCC 8739 putative DNA uptake protein YP_001723304.1 348747 R 481805 CDS YP_001723305.1 170018351 6066128 complement(349381..350064) 1 NC_010468.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 350064 6066128 EcolC_0300 Escherichia coli ATCC 8739 gluconate periplasmic binding protein YP_001723305.1 349381 R 481805 CDS YP_001723306.1 170018352 6066180 350102..350872 1 NC_010468.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 350872 6066180 EcolC_0301 Escherichia coli ATCC 8739 carboxylesterase BioH YP_001723306.1 350102 D 481805 CDS YP_001723307.1 170018353 6066251 complement(350901..351779) 1 NC_010468.1 PFAM: putative transposase YhgA family protein; KEGG: sbo:SBO_3400 hypothetical protein; hypothetical protein 351779 6066251 EcolC_0302 Escherichia coli ATCC 8739 hypothetical protein YP_001723307.1 350901 R 481805 CDS YP_001723308.1 170018354 6066188 complement(351982..352218) 1 NC_010468.1 PFAM: Protein of unknown function DUF1920; KEGG: ssn:SSON_3541 hypothetical protein; hypothetical protein 352218 6066188 EcolC_0303 Escherichia coli ATCC 8739 hypothetical protein YP_001723308.1 351982 R 481805 CDS YP_001723309.1 170018355 6065200 complement(352218..354539) 1 NC_010468.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 354539 feoB 6065200 feoB Escherichia coli ATCC 8739 ferrous iron transport protein B YP_001723309.1 352218 R 481805 CDS YP_001723310.1 170018356 6064864 complement(354556..354783) 1 NC_010468.1 PFAM: FeoA family protein; KEGG: sdy:SDY_3668 ferrous iron transport protein A; ferrous iron transport protein A 354783 feoA 6064864 feoA Escherichia coli ATCC 8739 ferrous iron transport protein A YP_001723310.1 354556 R 481805 CDS YP_001723311.1 170018357 6064867 complement(355221..357542) 1 NC_010468.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: sfv:SFV_3412 hypothetical protein; RNA-binding S1 domain-containing protein 357542 6064867 EcolC_0306 Escherichia coli ATCC 8739 RNA-binding S1 domain-containing protein YP_001723311.1 355221 R 481805 CDS YP_001723312.1 170018358 6064991 complement(357639..358115) 1 NC_010468.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 358115 greB 6064991 greB Escherichia coli ATCC 8739 transcription elongation factor GreB YP_001723312.1 357639 R 481805 CDS YP_001723313.1 170018359 6065427 358343..359062 1 NC_010468.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 359062 ompR 6065427 ompR Escherichia coli ATCC 8739 osmolarity response regulator YP_001723313.1 358343 D 481805 CDS YP_001723314.1 170018360 6065497 359059..360411 1 NC_010468.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 360411 envZ 6065497 envZ Escherichia coli ATCC 8739 osmolarity sensor protein YP_001723314.1 359059 D 481805 CDS YP_001723315.1 170018361 6065068 complement(360487..362109) 1 NC_010468.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 362109 6065068 EcolC_0310 Escherichia coli ATCC 8739 phosphoenolpyruvate carboxykinase YP_001723315.1 360487 R 481805 CDS YP_001723316.1 170018362 6065954 362488..364212 1 NC_010468.1 KEGG: sbo:SBO_3389 putative transport; putative transport protein 364212 6065954 EcolC_0311 Escherichia coli ATCC 8739 putative transport protein YP_001723316.1 362488 D 481805 CDS YP_001723317.1 170018363 6066790 complement(364275..365159) 1 NC_010468.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 365159 hslO 6066790 hslO Escherichia coli ATCC 8739 Hsp33-like chaperonin YP_001723317.1 364275 R 481805 CDS YP_001723318.1 170018364 6065293 complement(365178..365579) 1 NC_010468.1 PFAM: RNA-binding S4 domain protein; KEGG: sdy:SDY_3678 hypothetical protein; ribosome-associated heat shock protein Hsp15 365579 6065293 EcolC_0313 Escherichia coli ATCC 8739 ribosome-associated heat shock protein Hsp15 YP_001723318.1 365178 R 481805 CDS YP_001723319.1 170018365 6066864 complement(365590..366258) 1 NC_010468.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdy:SDY_3679 putative phosphatase; HAD family hydrolase 366258 6066864 EcolC_0314 Escherichia coli ATCC 8739 HAD family hydrolase YP_001723319.1 365590 R 481805 CDS YP_001723320.1 170018366 6066344 complement(366323..368458) 1 NC_010468.1 PFAM: Intracellular growth attenuator IgaA; KEGG: sfv:SFV_3403 putative dehydrogenase; intracellular growth attenuator IgaA 368458 6066344 EcolC_0315 Escherichia coli ATCC 8739 intracellular growth attenuator IgaA YP_001723320.1 366323 R 481805 CDS YP_001723321.1 170018367 6066035 368778..369338 1 NC_010468.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 369338 nudE 6066035 nudE Escherichia coli ATCC 8739 ADP-ribose diphosphatase NudE YP_001723321.1 368778 D 481805 CDS YP_001723322.1 170018368 6065992 complement(369506..372058) 1 NC_010468.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 372058 mrcA 6065992 mrcA Escherichia coli ATCC 8739 peptidoglycan synthetase YP_001723322.1 369506 R 481805 CDS YP_001723323.1 170018369 6065739 372178..372957 1 NC_010468.1 KEGG: sfv:SFV_3400 hypothetical protein; hypothetical protein 372957 6065739 EcolC_0318 Escherichia coli ATCC 8739 hypothetical protein YP_001723323.1 372178 D 481805 CDS YP_001723324.1 170018370 6067405 372957..373496 1 NC_010468.1 PFAM: Fimbrial assembly family protein; KEGG: sfv:SFV_3399 hypothetical protein; fimbrial assembly family protein 373496 6067405 EcolC_0319 Escherichia coli ATCC 8739 fimbrial assembly family protein YP_001723324.1 372957 D 481805 CDS YP_001723325.1 170018371 6068742 373480..373920 1 NC_010468.1 KEGG: sfv:SFV_3398 hypothetical protein; hypothetical protein 373920 6068742 EcolC_0320 Escherichia coli ATCC 8739 hypothetical protein YP_001723325.1 373480 D 481805 CDS YP_001723326.1 170018372 6067271 373910..374314 1 NC_010468.1 KEGG: sdy:SDY_3687 hypothetical protein; hypothetical protein 374314 6067271 EcolC_0321 Escherichia coli ATCC 8739 hypothetical protein YP_001723326.1 373910 D 481805 CDS YP_001723327.1 170018373 6065266 374304..375464 1 NC_010468.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 375464 hofQ 6065266 hofQ Escherichia coli ATCC 8739 outer membrane porin HofQ YP_001723327.1 374304 D 481805 CDS YP_001723328.1 170018374 6065347 375865..376386 1 NC_010468.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 376386 aroK 6065347 aroK Escherichia coli ATCC 8739 shikimate kinase I YP_001723328.1 375865 D 481805 CDS YP_001723329.1 170018375 6065354 376443..377531 1 NC_010468.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 377531 aroB 6065354 aroB Escherichia coli ATCC 8739 3-dehydroquinate synthase YP_001723329.1 376443 D 481805 CDS YP_001723330.1 170018376 6065381 377623..378909 1 NC_010468.1 PFAM: Sporulation domain protein; KEGG: sbo:SBO_3375 DamX; hypothetical protein 378909 6065381 EcolC_0325 Escherichia coli ATCC 8739 hypothetical protein YP_001723330.1 377623 D 481805 CDS YP_001723331.1 170018377 6065416 379016..379852 1 NC_010468.1 KEGG: sbo:SBO_3374 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; DNA adenine methylase 379852 6065416 EcolC_0326 Escherichia coli ATCC 8739 DNA adenine methylase YP_001723331.1 379016 D 481805 CDS YP_001723332.1 170018378 6065470 379870..380547 1 NC_010468.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 380547 6065470 EcolC_0327 Escherichia coli ATCC 8739 ribulose-phosphate 3-epimerase YP_001723332.1 379870 D 481805 CDS YP_001723333.1 170018379 6065474 380540..381298 1 NC_010468.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 381298 6065474 EcolC_0328 Escherichia coli ATCC 8739 phosphoglycolate phosphatase YP_001723333.1 380540 D 481805 CDS YP_001723334.1 170018380 6065522 381291..382295 1 NC_010468.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 382295 6065522 EcolC_0329 Escherichia coli ATCC 8739 tryptophanyl-tRNA synthetase YP_001723334.1 381291 D 481805 CDS YP_001723335.1 170018381 6065551 382585..383490 1 NC_010468.1 KEGG: cko:CKO_04803 hypothetical protein; hypothetical protein 383490 6065551 EcolC_0330 Escherichia coli ATCC 8739 hypothetical protein YP_001723335.1 382585 D 481805 CDS YP_001723336.1 170018382 6065554 383507..383869 1 NC_010468.1 KEGG: sbo:SBO_3369 hypothetical protein; hypothetical protein 383869 6065554 EcolC_0331 Escherichia coli ATCC 8739 hypothetical protein YP_001723336.1 383507 D 481805 CDS YP_001723337.1 170018383 6065562 383953..385116 1 NC_010468.1 PFAM: alanine racemase domain protein; KEGG: sbo:SBO_3368 hypothetical protein; alanine racemase domain-containing protein 385116 6065562 EcolC_0332 Escherichia coli ATCC 8739 alanine racemase domain-containing protein YP_001723337.1 383953 D 481805 CDS YP_001723338.1 170018384 6065569 385116..386342 1 NC_010468.1 PFAM: metalloenzyme domain protein; Phosphopentomutase domain protein; KEGG: sfv:SFV_3385 putative mutase; putative mutase 386342 6065569 EcolC_0333 Escherichia coli ATCC 8739 putative mutase YP_001723338.1 385116 D 481805 CDS YP_001723339.1 170018385 6065603 386339..387217 1 NC_010468.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase 387217 6065603 EcolC_0334 Escherichia coli ATCC 8739 putative hydrolase YP_001723339.1 386339 D 481805 CDS YP_001723340.1 170018386 6065607 387228..387581 1 NC_010468.1 KEGG: sfv:SFV_3383 hypothetical protein; hypothetical protein 387581 6065607 EcolC_0335 Escherichia coli ATCC 8739 hypothetical protein YP_001723340.1 387228 D 481805 CDS YP_001723341.1 170018387 6065652 387593..388897 1 NC_010468.1 KEGG: sfx:S4367 putative transport system permease protein; putative transport system permease 388897 6065652 EcolC_0336 Escherichia coli ATCC 8739 putative transport system permease YP_001723341.1 387593 D 481805 CDS YP_001723342.1 170018388 6065661 388909..389994 1 NC_010468.1 KEGG: sbo:SBO_3363 hypothetical protein; GntR family transcriptional regulator 389994 6065661 EcolC_0337 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001723342.1 388909 D 481805 CDS YP_001723343.1 170018389 6065669 complement(390146..390877) 1 NC_010468.1 may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 390877 6065669 EcolC_0338 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator FrlR YP_001723343.1 390146 R 481805 CDS YP_001723344.1 170018390 6065750 complement(390977..391762) 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: sfv:SFV_3379 putative kinase; fructoselysine 6-kinase 391762 6065750 EcolC_0339 Escherichia coli ATCC 8739 fructoselysine 6-kinase YP_001723344.1 390977 R 481805 CDS YP_001723345.1 170018391 6065779 complement(391759..392589) 1 NC_010468.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 392589 6065779 EcolC_0340 Escherichia coli ATCC 8739 fructoselysine 3-epimerase YP_001723345.1 391759 R 481805 CDS YP_001723346.1 170018392 6065791 complement(392639..393661) 1 NC_010468.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 393661 frlB 6065791 frlB Escherichia coli ATCC 8739 fructoselysine-6-P-deglycase YP_001723346.1 392639 R 481805 CDS YP_001723347.1 170018393 6065819 complement(393682..395019) 1 NC_010468.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter 395019 frlA 6065819 frlA Escherichia coli ATCC 8739 putative fructoselysine transporter YP_001723347.1 393682 R 481805 CDS YP_001723348.1 170018394 6065868 complement(395314..395481) 1 NC_010468.1 KEGG: sbo:SBO_3357 hypothetical protein; hypothetical protein 395481 6065868 EcolC_0343 Escherichia coli ATCC 8739 hypothetical protein YP_001723348.1 395314 R 481805 CDS YP_001723349.1 170018395 6065889 complement(395728..397101) 1 NC_010468.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 397101 cysG 6065889 cysG Escherichia coli ATCC 8739 siroheme synthase YP_001723349.1 395728 R 481805 CDS YP_001723350.1 170018396 6065909 complement(397120..397926) 1 NC_010468.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 397926 6065909 EcolC_0345 Escherichia coli ATCC 8739 nitrite transporter NirC YP_001723350.1 397120 R 481805 CDS YP_001723351.1 170018397 6065938 complement(398053..398379) 1 NC_010468.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 398379 nirD 6065938 nirD Escherichia coli ATCC 8739 nitrite reductase small subunit YP_001723351.1 398053 R 481805 CDS YP_001723352.1 170018398 6065965 complement(398376..400919) 1 NC_010468.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ssn:SSON_3496 nitrite reductase (NAD(P)H) subunit; nitrite reductase (NAD(P)H) large subunit 400919 6065965 EcolC_0347 Escherichia coli ATCC 8739 nitrite reductase (NAD(P)H) large subunit YP_001723352.1 398376 R 481805 CDS YP_001723353.1 170018399 6065975 complement(401181..402362) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_3346 putative transport; hypothetical protein 402362 6065975 EcolC_0348 Escherichia coli ATCC 8739 hypothetical protein YP_001723353.1 401181 R 481805 CDS YP_001723354.1 170018400 6066003 402633..403205 1 NC_010468.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ssn:SSON_3494 peptidyl-prolyl cis-trans isomerase A; peptidyl-prolyl cis-trans isomerase A 403205 6066003 EcolC_0349 Escherichia coli ATCC 8739 peptidyl-prolyl cis-trans isomerase A YP_001723354.1 402633 D 481805 CDS YP_001723355.1 170018401 6066032 403310..403477 1 NC_010468.1 KEGG: ssn:SSON_3493 hypothetical protein; hypothetical protein 403477 6066032 EcolC_0350 Escherichia coli ATCC 8739 hypothetical protein YP_001723355.1 403310 D 481805 CDS YP_001723356.1 170018402 6066061 403467..404069 1 NC_010468.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: sfv:SFV_3367 cell filamentation protein fic; cell filamentation protein Fic 404069 6066061 EcolC_0351 Escherichia coli ATCC 8739 cell filamentation protein Fic YP_001723356.1 403467 D 481805 CDS YP_001723357.1 170018403 6066078 404101..404664 1 NC_010468.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 404664 6066078 EcolC_0352 Escherichia coli ATCC 8739 para-aminobenzoate synthase component II YP_001723357.1 404101 D 481805 CDS YP_001723358.1 170018404 6066091 404750..405970 1 NC_010468.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 405970 argD 6066091 argD Escherichia coli ATCC 8739 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_001723358.1 404750 D 481805 CDS YP_001723359.1 170018405 6066096 complement(406037..408127) 1 NC_010468.1 TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_3489 hypothetical protein; YccS/YhfK family integral membrane protein 408127 6066096 EcolC_0354 Escherichia coli ATCC 8739 YccS/YhfK family integral membrane protein YP_001723359.1 406037 R 481805 CDS YP_001723360.1 170018406 6066107 complement(408178..408810) 1 NC_010468.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 408810 6066107 EcolC_0355 Escherichia coli ATCC 8739 cAMP-regulatory protein YP_001723360.1 408178 R 481805 CDS YP_001723361.1 170018407 6066115 409112..409516 1 NC_010468.1 PFAM: OsmC family protein; KEGG: sdy:SDY_3518 hypothetical protein; hypothetical protein 409516 6066115 EcolC_0356 Escherichia coli ATCC 8739 hypothetical protein YP_001723361.1 409112 D 481805 CDS YP_001723362.1 170018408 6066126 complement(409571..410440) 1 NC_010468.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: sbo:SBO_3335 probable phosphoribulokinase; phosphoribulokinase 410440 6066126 EcolC_0357 Escherichia coli ATCC 8739 phosphoribulokinase YP_001723362.1 409571 R 481805 CDS YP_001723363.1 170018409 6066194 complement(410494..410712) 1 NC_010468.1 PFAM: protein of unknown function UPF0270; KEGG: sbo:SBO_3334 hypothetical protein; hypothetical protein 410712 6066194 EcolC_0358 Escherichia coli ATCC 8739 hypothetical protein YP_001723363.1 410494 R 481805 CDS YP_001723364.1 170018410 6066222 complement(410706..411728) 1 NC_010468.1 PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_3484 hypothetical protein; putative hydrolase 411728 6066222 EcolC_0359 Escherichia coli ATCC 8739 putative hydrolase YP_001723364.1 410706 R 481805 CDS YP_001723365.1 170018411 6066261 complement(411728..413641) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_3483 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein 413641 6066261 EcolC_0360 Escherichia coli ATCC 8739 putative ABC transporter ATP-binding protein YP_001723365.1 411728 R 481805 CDS YP_001723366.1 170018412 6066267 413772..414323 1 NC_010468.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 414323 6066267 EcolC_0361 Escherichia coli ATCC 8739 glutathione-regulated potassium-efflux system ancillary protein KefG YP_001723366.1 413772 D 481805 CDS YP_001723367.1 170018413 6066286 414323..416128 1 NC_010468.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 416128 6066286 EcolC_0362 Escherichia coli ATCC 8739 glutathione-regulated potassium-efflux system protein KefB YP_001723367.1 414323 D 481805 CDS YP_001723368.1 170018414 6066323 416138..416338 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3511 hypothetical protein; hypothetical protein 416338 6066323 EcolC_0363 Escherichia coli ATCC 8739 hypothetical protein YP_001723368.1 416138 D 481805 CDS YP_001723369.1 170018415 6066359 416433..417023 1 NC_010468.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 417023 6066359 EcolC_0364 Escherichia coli ATCC 8739 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001723369.1 416433 D 481805 CDS YP_001723370.1 170018416 6066368 complement(417072..417290) 1 NC_010468.1 PFAM: SlyX family protein; KEGG: sdy:SDY_3509 host factor for lysis of phiX174 infection; hypothetical protein 417290 6066368 EcolC_0365 Escherichia coli ATCC 8739 hypothetical protein YP_001723370.1 417072 R 481805 CDS YP_001723371.1 170018417 6066379 417511..418323 1 NC_010468.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 418323 6066379 EcolC_0366 Escherichia coli ATCC 8739 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001723371.1 417511 D 481805 CDS YP_001723372.1 170018418 6066396 418490..419212 1 NC_010468.1 PFAM: YheO domain protein; KEGG: sbo:SBO_3326 hypothetical protein; YheO domain-containing protein 419212 6066396 EcolC_0367 Escherichia coli ATCC 8739 YheO domain-containing protein YP_001723372.1 418490 D 481805 CDS YP_001723373.1 170018419 6066408 419212..419598 1 NC_010468.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 419598 6066408 EcolC_0368 Escherichia coli ATCC 8739 sulfur transfer complex subunit TusD YP_001723373.1 419212 D 481805 CDS YP_001723374.1 170018420 6066421 419598..419957 1 NC_010468.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 419957 6066421 EcolC_0369 Escherichia coli ATCC 8739 sulfur relay protein TusC YP_001723374.1 419598 D 481805 CDS YP_001723375.1 170018421 6066429 419965..420252 1 NC_010468.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 420252 6066429 EcolC_0370 Escherichia coli ATCC 8739 sulfur transfer complex subunit TusB YP_001723375.1 419965 D 481805 CDS YP_001723376.1 170018422 6066439 420378..420752 1 NC_010468.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 420752 rpsL 6066439 rpsL Escherichia coli ATCC 8739 30S ribosomal protein S12 YP_001723376.1 420378 D 481805 CDS YP_001723377.1 170018423 6066482 420849..421319 1 NC_010468.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 421319 6066482 EcolC_0372 Escherichia coli ATCC 8739 30S ribosomal protein S7 YP_001723377.1 420849 D 481805 CDS YP_001723378.1 170018424 6066502 421416..423530 1 NC_010468.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 423530 6066502 EcolC_0373 Escherichia coli ATCC 8739 elongation factor G YP_001723378.1 421416 D 481805 CDS YP_001723379.1 170018425 6066530 423601..424785 1 NC_010468.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 424785 6066530 EcolC_0374 Escherichia coli ATCC 8739 elongation factor Tu YP_001723379.1 423601 D 481805 CDS YP_001723380.1 170018426 6066557 425077..427770 1 NC_010468.1 PFAM: Carbohydrate-binding family V/XII; KEGG: cbh:CLC_1134 putative glycosyl hydrolase; lysozyme 427770 6066557 EcolC_0375 Escherichia coli ATCC 8739 lysozyme YP_001723380.1 425077 D 481805 CDS YP_001723381.1 170018427 6066591 427939..428133 1 NC_010468.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: cko:CKO_04744 hypothetical protein; bacterioferritin-associated ferredoxin 428133 6066591 EcolC_0376 Escherichia coli ATCC 8739 bacterioferritin-associated ferredoxin YP_001723381.1 427939 D 481805 CDS YP_001723382.1 170018428 6066615 428205..428681 1 NC_010468.1 iron storage protein; bacterioferritin 428681 6066615 EcolC_0377 Escherichia coli ATCC 8739 bacterioferritin YP_001723382.1 428205 D 481805 CDS YP_001723383.1 170018429 6066623 complement(428710..429387) 1 NC_010468.1 PFAM: peptidase A24A prepilin type IV; KEGG: kpn:KPN_00149 pullulanase Q protein; peptidase A24A prepilin type IV 429387 6066623 EcolC_0378 Escherichia coli ATCC 8739 peptidase A24A prepilin type IV YP_001723383.1 428710 R 481805 CDS YP_001723384.1 170018430 6066626 complement(429387..429848) 1 NC_010468.1 PFAM: General secretion pathway M protein; general secretion pathway M protein 429848 6066626 EcolC_0379 Escherichia coli ATCC 8739 general secretion pathway M protein YP_001723384.1 429387 R 481805 CDS YP_001723385.1 170018431 6066666 complement(429845..431008) 1 NC_010468.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: cko:CKO_02220 hypothetical protein; general secretion pathway protein L 431008 6066666 EcolC_0380 Escherichia coli ATCC 8739 general secretion pathway protein L YP_001723385.1 429845 R 481805 CDS YP_001723386.1 170018432 6066693 complement(431023..432006) 1 NC_010468.1 PFAM: General secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K; general secretion pathway protein K 432006 6066693 EcolC_0381 Escherichia coli ATCC 8739 general secretion pathway protein K YP_001723386.1 431023 R 481805 CDS YP_001723387.1 170018433 6066733 complement(431999..432586) 1 NC_010468.1 TIGRFAM: general secretion pathway protein J; KEGG: vpa:VP0139 general secretion pathway protein J; general secretion pathway protein J 432586 6066733 EcolC_0382 Escherichia coli ATCC 8739 general secretion pathway protein J YP_001723387.1 431999 R 481805 CDS YP_001723388.1 170018434 6066738 complement(432579..432956) 1 NC_010468.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: pap:PSPA7_2034 general secretion pathway protein I; general secretion pathway protein I 432956 6066738 EcolC_0383 Escherichia coli ATCC 8739 general secretion pathway protein I YP_001723388.1 432579 R 481805 CDS YP_001723389.1 170018435 6066742 complement(432953..433462) 1 NC_010468.1 TIGRFAM: general secretion pathway protein H; KEGG: kpn:KPN_00156 pullulanase H protein; general secretion pathway protein H 433462 6066742 EcolC_0384 Escherichia coli ATCC 8739 general secretion pathway protein H YP_001723389.1 432953 R 481805 CDS YP_001723390.1 170018436 6066750 complement(433470..433907) 1 NC_010468.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: cko:CKO_02225 hypothetical protein; general secretion pathway protein G 433907 6066750 EcolC_0385 Escherichia coli ATCC 8739 general secretion pathway protein G YP_001723390.1 433470 R 481805 CDS YP_001723391.1 170018437 6066755 complement(433917..435113) 1 NC_010468.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: cko:CKO_02226 hypothetical protein; general secretion pathway protein F 435113 6066755 EcolC_0386 Escherichia coli ATCC 8739 general secretion pathway protein F YP_001723391.1 433917 R 481805 CDS YP_001723392.1 170018438 6066774 complement(435110..436591) 1 NC_010468.1 KEGG: cko:CKO_02227 hypothetical protein; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase; general secretory pathway protein E 436591 6066774 EcolC_0387 Escherichia coli ATCC 8739 general secretory pathway protein E YP_001723392.1 435110 R 481805 CDS YP_001723393.1 170018439 6066786 complement(436601..438565) 1 NC_010468.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: cko:CKO_02228 hypothetical protein; general secretion pathway protein D 438565 6066786 EcolC_0388 Escherichia coli ATCC 8739 general secretion pathway protein D YP_001723393.1 436601 R 481805 CDS YP_001723394.1 170018440 6066816 complement(438537..439352) 1 NC_010468.1 TIGRFAM: general secretion pathway protein C; KEGG: kpn:KPN_00161 pullulanase C protein; general secretion pathway protein C 439352 6066816 EcolC_0389 Escherichia coli ATCC 8739 general secretion pathway protein C YP_001723394.1 438537 R 481805 CDS YP_001723395.1 170018441 6066836 439532..441001 1 NC_010468.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: cko:CKO_02233 hypothetical protein; peptidoglycan binding domain-containing protein 441001 6066836 EcolC_0390 Escherichia coli ATCC 8739 peptidoglycan binding domain-containing protein YP_001723395.1 439532 D 481805 CDS YP_001723396.1 170018442 6066861 441003..441422 1 NC_010468.1 calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 441422 6066861 EcolC_0391 Escherichia coli ATCC 8739 chromosome replication protein PioO YP_001723396.1 441003 D 481805 CDS YP_001723397.1 170018443 6066873 441660..441971 1 NC_010468.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 441971 rpsJ 6066873 rpsJ Escherichia coli ATCC 8739 30S ribosomal protein S10 YP_001723397.1 441660 D 481805 CDS YP_001723398.1 170018444 6066884 442004..442633 1 NC_010468.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 442633 rplC 6066884 rplC Escherichia coli ATCC 8739 50S ribosomal protein L3 YP_001723398.1 442004 D 481805 CDS YP_001723399.1 170018445 6066899 442644..443249 1 NC_010468.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 443249 rplD 6066899 rplD Escherichia coli ATCC 8739 50S ribosomal protein L4 YP_001723399.1 442644 D 481805 CDS YP_001723400.1 170018446 6066907 443246..443548 1 NC_010468.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 443548 rplW 6066907 rplW Escherichia coli ATCC 8739 50S ribosomal protein L23 YP_001723400.1 443246 D 481805 CDS YP_001723401.1 170018447 6066928 443566..444387 1 NC_010468.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 444387 rplB 6066928 rplB Escherichia coli ATCC 8739 50S ribosomal protein L2 YP_001723401.1 443566 D 481805 CDS YP_001723402.1 170018448 6066940 444404..444682 1 NC_010468.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 444682 rpsS 6066940 rpsS Escherichia coli ATCC 8739 30S ribosomal protein S19 YP_001723402.1 444404 D 481805 CDS YP_001723403.1 170018449 6066953 444697..445029 1 NC_010468.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 445029 rplV 6066953 rplV Escherichia coli ATCC 8739 50S ribosomal protein L22 YP_001723403.1 444697 D 481805 CDS YP_001723404.1 170018450 6066973 445047..445748 1 NC_010468.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 445748 rpsC 6066973 rpsC Escherichia coli ATCC 8739 30S ribosomal protein S3 YP_001723404.1 445047 D 481805 CDS YP_001723405.1 170018451 6067014 445761..446171 1 NC_010468.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 446171 rplP 6067014 rplP Escherichia coli ATCC 8739 50S ribosomal protein L16 YP_001723405.1 445761 D 481805 CDS YP_001723406.1 170018452 6067062 446171..446362 1 NC_010468.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 446362 6067062 EcolC_0401 Escherichia coli ATCC 8739 50S ribosomal protein L29 YP_001723406.1 446171 D 481805 CDS YP_001723407.1 170018453 6067115 446362..446616 1 NC_010468.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 446616 rpsQ 6067115 rpsQ Escherichia coli ATCC 8739 30S ribosomal protein S17 YP_001723407.1 446362 D 481805 CDS YP_001723408.1 170018454 6067146 446781..447152 1 NC_010468.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 447152 rplN 6067146 rplN Escherichia coli ATCC 8739 50S ribosomal protein L14 YP_001723408.1 446781 D 481805 CDS YP_001723409.1 170018455 6067186 447163..447477 1 NC_010468.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 447477 rplX 6067186 rplX Escherichia coli ATCC 8739 50S ribosomal protein L24 YP_001723409.1 447163 D 481805 CDS YP_001723410.1 170018456 6067191 447492..448031 1 NC_010468.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 448031 rplE 6067191 rplE Escherichia coli ATCC 8739 50S ribosomal protein L5 YP_001723410.1 447492 D 481805 CDS YP_001723411.1 170018457 6067218 448046..448351 1 NC_010468.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 448351 rpsN 6067218 rpsN Escherichia coli ATCC 8739 30S ribosomal protein S14 YP_001723411.1 448046 D 481805 CDS YP_001723412.1 170018458 6067299 448385..448777 1 NC_010468.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 448777 rpsH 6067299 rpsH Escherichia coli ATCC 8739 30S ribosomal protein S8 YP_001723412.1 448385 D 481805 CDS YP_001723413.1 170018459 6067337 448790..449323 1 NC_010468.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 449323 rplF 6067337 rplF Escherichia coli ATCC 8739 50S ribosomal protein L6 YP_001723413.1 448790 D 481805 CDS YP_001723414.1 170018460 6067341 449333..449686 1 NC_010468.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 449686 rplR 6067341 rplR Escherichia coli ATCC 8739 50S ribosomal protein L18 YP_001723414.1 449333 D 481805 CDS YP_001723415.1 170018461 6067346 449701..450204 1 NC_010468.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 450204 rpsE 6067346 rpsE Escherichia coli ATCC 8739 30S ribosomal protein S5 YP_001723415.1 449701 D 481805 CDS YP_001723416.1 170018462 6067375 450208..450387 1 NC_010468.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 450387 rpmD 6067375 rpmD Escherichia coli ATCC 8739 50S ribosomal protein L30 YP_001723416.1 450208 D 481805 CDS YP_001723417.1 170018463 6067402 450391..450825 1 NC_010468.1 late assembly protein; 50S ribosomal protein L15 450825 rplO 6067402 rplO Escherichia coli ATCC 8739 50S ribosomal protein L15 YP_001723417.1 450391 D 481805 CDS YP_001723418.1 170018464 6067423 450833..452164 1 NC_010468.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 452164 secY 6067423 secY Escherichia coli ATCC 8739 preprotein translocase subunit SecY YP_001723418.1 450833 D 481805 CDS YP_001723419.1 170018465 6067490 452196..452312 1 NC_010468.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 452312 rpmJ 6067490 rpmJ Escherichia coli ATCC 8739 50S ribosomal protein L36 YP_001723419.1 452196 D 481805 CDS YP_001723420.1 170018466 6067510 452459..452815 1 NC_010468.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 452815 rpsM 6067510 rpsM Escherichia coli ATCC 8739 30S ribosomal protein S13 YP_001723420.1 452459 D 481805 CDS YP_001723421.1 170018467 6067533 452832..453221 1 NC_010468.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 453221 6067533 EcolC_0416 Escherichia coli ATCC 8739 30S ribosomal protein S11 YP_001723421.1 452832 D 481805 CDS YP_001723422.1 170018468 6067536 453255..453875 1 NC_010468.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 453875 rpsD 6067536 rpsD Escherichia coli ATCC 8739 30S ribosomal protein S4 YP_001723422.1 453255 D 481805 CDS YP_001723423.1 170018469 6067559 453901..454890 1 NC_010468.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 454890 6067559 EcolC_0418 Escherichia coli ATCC 8739 DNA-directed RNA polymerase subunit alpha YP_001723423.1 453901 D 481805 CDS YP_001723424.1 170018470 6067585 454931..455314 1 NC_010468.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 455314 rplQ 6067585 rplQ Escherichia coli ATCC 8739 50S ribosomal protein L17 YP_001723424.1 454931 D 481805 CDS YP_001723425.1 170018471 6067590 455421..455789 1 NC_010468.1 KEGG: ssn:SSON_3434 hypothetical protein; hypothetical protein 455789 6067590 EcolC_0420 Escherichia coli ATCC 8739 hypothetical protein YP_001723425.1 455421 D 481805 CDS YP_001723426.1 170018472 6067620 455800..456225 1 NC_010468.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 456225 zntR 6067620 zntR Escherichia coli ATCC 8739 zinc-responsive transcriptional regulator YP_001723426.1 455800 D 481805 CDS YP_001723427.1 170018473 6067630 456281..456499 1 NC_010468.1 PFAM: protein of unknown function DUF331; KEGG: ssn:SSON_3432 hypothetical protein; hypothetical protein 456499 6067630 EcolC_0422 Escherichia coli ATCC 8739 hypothetical protein YP_001723427.1 456281 D 481805 CDS YP_001723428.1 170018474 6067654 complement(456496..456906) 1 NC_010468.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 456906 mscL 6067654 mscL Escherichia coli ATCC 8739 large-conductance mechanosensitive channel YP_001723428.1 456496 R 481805 CDS YP_001723429.1 170018475 6067682 complement(457036..458412) 1 NC_010468.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 458412 trkA 6067682 trkA Escherichia coli ATCC 8739 potassium transporter peripheral membrane protein YP_001723429.1 457036 R 481805 CDS YP_001723430.1 170018476 6067698 complement(458434..459723) 1 NC_010468.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 459723 6067698 EcolC_0425 Escherichia coli ATCC 8739 16S rRNA methyltransferase B YP_001723430.1 458434 R 481805 CDS YP_001723431.1 170018477 6067707 complement(459769..460716) 1 NC_010468.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 460716 fmt 6067707 fmt Escherichia coli ATCC 8739 methionyl-tRNA formyltransferase YP_001723431.1 459769 R 481805 CDS YP_001723432.1 170018478 6067709 complement(460731..461240) 1 NC_010468.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 461240 def 6067709 def Escherichia coli ATCC 8739 peptide deformylase YP_001723432.1 460731 R 481805 CDS YP_001723433.1 170018479 6067714 461370..462494 1 NC_010468.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: sdy:SDY_3462 predicted Rossmann-fold nucleotide-binding protein; DNA protecting protein DprA 462494 6067714 EcolC_0428 Escherichia coli ATCC 8739 DNA protecting protein DprA YP_001723433.1 461370 D 481805 CDS YP_001723434.1 170018480 6067721 462466..462939 1 NC_010468.1 PFAM: protein of unknown function DUF494; KEGG: sbo:SBO_3278 hypothetical protein; hypothetical protein 462939 6067721 EcolC_0429 Escherichia coli ATCC 8739 hypothetical protein YP_001723434.1 462466 D 481805 CDS YP_001723435.1 170018481 6067724 462968..463510 1 NC_010468.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: sdy:SDY_3460 putative DNA topoisomerase; DNA topoisomerase type IA Zn finger domain-containing protein 463510 6067724 EcolC_0430 Escherichia coli ATCC 8739 DNA topoisomerase type IA Zn finger domain-containing protein YP_001723435.1 462968 D 481805 CDS YP_001723436.1 170018482 6067727 463515..464087 1 NC_010468.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor 464087 6067727 EcolC_0431 Escherichia coli ATCC 8739 putative ribosome maturation factor YP_001723436.1 463515 D 481805 CDS YP_001723437.1 170018483 6067735 464092..464910 1 NC_010468.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 464910 aroE 6067735 aroE Escherichia coli ATCC 8739 shikimate 5-dehydrogenase YP_001723437.1 464092 D 481805 CDS YP_001723438.1 170018484 6067737 464907..465164 1 NC_010468.1 PFAM: protein of unknown function DUF1488; KEGG: sbo:SBO_3274 hypothetical protein; hypothetical protein 465164 6067737 EcolC_0433 Escherichia coli ATCC 8739 hypothetical protein YP_001723438.1 464907 D 481805 CDS YP_001723439.1 170018485 6067740 complement(465140..465694) 1 NC_010468.1 KEGG: ssn:SSON_3420 putative transferase; putative transferase 465694 6067740 EcolC_0434 Escherichia coli ATCC 8739 putative transferase YP_001723439.1 465140 R 481805 CDS YP_001723440.1 170018486 6067863 complement(471747..472505) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_3265 putative ATP-binding component of a transport system; ABC transporter-like protein 472505 6067863 EcolC_0435 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001723440.1 471747 R 481805 CDS YP_001723441.1 170018487 6067883 complement(472513..473616) 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_3447 putative transport system permease protein; polar amino acid ABC transporter inner membrane protein 473616 6067883 EcolC_0436 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001723441.1 472513 R 481805 CDS YP_001723442.1 170018488 6067910 complement(473626..474807) 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cko:CKO_04682 hypothetical protein; polar amino acid ABC transporter inner membrane protein 474807 6067910 EcolC_0437 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001723442.1 473626 R 481805 CDS YP_001723443.1 170018489 6067924 complement(474875..475900) 1 NC_010468.1 SMART: extracellular solute-binding protein family 3; KEGG: sfv:SFV_3290 putative periplasmic binding transport protein; extracellular solute-binding protein 475900 6067924 EcolC_0438 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001723443.1 474875 R 481805 CDS YP_001723444.1 170018490 6067945 complement(476331..476552) 1 NC_010468.1 KEGG: stm:STM3392 putative outer membrane lipoprotein; putative outer membrane lipoprotein 476552 6067945 EcolC_0439 Escherichia coli ATCC 8739 putative outer membrane lipoprotein YP_001723444.1 476331 R 481805 CDS YP_001723445.1 170018491 6067962 complement(476805..479909) 1 NC_010468.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_3260 integral transmembrane protein; hydrophobe/amphiphile efflux-1 (HAE1) family protein 479909 6067962 EcolC_0440 Escherichia coli ATCC 8739 hydrophobe/amphiphile efflux-1 (HAE1) family protein YP_001723445.1 476805 R 481805 CDS YP_001723446.1 170018492 6067987 complement(479921..481078) 1 NC_010468.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_3406 AcrE; RND family efflux transporter MFP subunit 481078 6067987 EcolC_0441 Escherichia coli ATCC 8739 RND family efflux transporter MFP subunit YP_001723446.1 479921 R 481805 CDS YP_001723447.1 170018493 6068022 481477..482139 1 NC_010468.1 PFAM: regulatory protein TetR; Tetracycline transcriptional repressor MAATS-type domain protein; KEGG: sbo:SBO_3258 putative transcriptional regulator; DNA-binding transcriptional regulator EnvR 482139 6068022 EcolC_0442 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator EnvR YP_001723447.1 481477 D 481805 CDS YP_001723448.1 170018494 6068150 complement(482142..482321) 1 NC_010468.1 KEGG: sbo:SBO_3257 hypothetical protein; hypothetical protein 482321 6068150 EcolC_0443 Escherichia coli ATCC 8739 hypothetical protein YP_001723448.1 482142 R 481805 CDS YP_001723449.1 170018495 6068168 complement(482405..483289) 1 NC_010468.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ssn:SSON_3403 putative methyltransferase; putative methyltransferase 483289 6068168 EcolC_0444 Escherichia coli ATCC 8739 putative methyltransferase YP_001723449.1 482405 R 481805 CDS YP_001723450.1 170018496 6068175 complement(483375..483671) 1 NC_010468.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 483671 fis 6068175 fis Escherichia coli ATCC 8739 DNA-binding protein Fis YP_001723450.1 483375 R 481805 CDS YP_001723451.1 170018497 6068193 complement(483697..484662) 1 NC_010468.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: sdy:SDY_3437 putative dehydrogenase; tRNA-dihydrouridine synthase B 484662 6068193 EcolC_0446 Escherichia coli ATCC 8739 tRNA-dihydrouridine synthase B YP_001723451.1 483697 R 481805 CDS YP_001723452.1 170018498 6068197 complement(484991..485872) 1 NC_010468.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 485872 prmA 6068197 prmA Escherichia coli ATCC 8739 50S ribosomal protein L11 methyltransferase YP_001723452.1 484991 R 481805 CDS YP_001723453.1 170018499 6068209 complement(485884..487335) 1 NC_010468.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 487335 panF 6068209 panF Escherichia coli ATCC 8739 sodium/panthothenate symporter YP_001723453.1 485884 R 481805 CDS YP_001723454.1 170018500 6068215 complement(487325..487567) 1 NC_010468.1 PFAM: protein of unknown function DUF997; KEGG: sdy:SDY_3434 hypothetical protein; hypothetical protein 487567 6068215 EcolC_0449 Escherichia coli ATCC 8739 hypothetical protein YP_001723454.1 487325 R 481805 CDS YP_001723455.1 170018501 6068219 complement(487676..489025) 1 NC_010468.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 489025 6068219 EcolC_0450 Escherichia coli ATCC 8739 acetyl-CoA carboxylase biotin carboxylase subunit YP_001723455.1 487676 R 481805 CDS YP_001723456.1 170018502 6068228 complement(489036..489506) 1 NC_010468.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 489506 6068228 EcolC_0451 Escherichia coli ATCC 8739 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_001723456.1 489036 R 481805 CDS YP_001723457.1 170018503 6068241 complement(490372..491202) 1 NC_010468.1 KEGG: sdy:SDY_3429 hypothetical protein; hypothetical protein 491202 6068241 EcolC_0453 Escherichia coli ATCC 8739 hypothetical protein YP_001723457.1 490372 R 481805 CDS YP_001723458.1 170018504 6068254 complement(491239..492213) 1 NC_010468.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_3394 putative dehydrogenase; quinone oxidoreductase 492213 6068254 EcolC_0454 Escherichia coli ATCC 8739 quinone oxidoreductase YP_001723458.1 491239 R 481805 CDS YP_001723459.1 170018505 6068260 492365..494305 1 NC_010468.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 494305 6068260 EcolC_0455 Escherichia coli ATCC 8739 regulatory protein CsrD YP_001723459.1 492365 D 481805 CDS YP_001723460.1 170018506 6068287 494610..495653 1 NC_010468.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 495653 6068287 EcolC_0456 Escherichia coli ATCC 8739 rod shape-determining protein MreB YP_001723460.1 494610 D 481805 CDS YP_001723461.1 170018507 6068294 495719..496822 1 NC_010468.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 496822 6068294 EcolC_0457 Escherichia coli ATCC 8739 rod shape-determining protein MreC YP_001723461.1 495719 D 481805 CDS YP_001723462.1 170018508 6068301 496822..497310 1 NC_010468.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 497310 6068301 EcolC_0458 Escherichia coli ATCC 8739 rod shape-determining protein MreD YP_001723462.1 496822 D 481805 CDS YP_001723463.1 170018509 6068308 497319..497912 1 NC_010468.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 497912 6068308 EcolC_0459 Escherichia coli ATCC 8739 Maf-like protein YP_001723463.1 497319 D 481805 CDS YP_001723464.1 170018510 6068313 497902..499371 1 NC_010468.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 499371 6068313 EcolC_0460 Escherichia coli ATCC 8739 ribonuclease G YP_001723464.1 497902 D 481805 CDS YP_001723465.1 170018511 6068318 499439..503239 1 NC_010468.1 KEGG: ssn:SSON_3387 uncharacterized membrane protein; hypothetical protein 503239 6068318 EcolC_0461 Escherichia coli ATCC 8739 hypothetical protein YP_001723465.1 499439 D 481805 CDS YP_001723466.1 170018512 6068338 503669..505114 1 NC_010468.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 505114 tldD 6068338 tldD Escherichia coli ATCC 8739 protease TldD YP_001723466.1 503669 D 481805 CDS YP_001723467.1 170018513 6068345 complement(505248..506177) 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3144 QseA; putative DNA-binding transcriptional regulator 506177 6068345 EcolC_0463 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001723467.1 505248 R 481805 CDS YP_001723468.1 170018514 6068349 506360..506563 1 NC_010468.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 506563 6068349 EcolC_0464 Escherichia coli ATCC 8739 hypothetical protein YP_001723468.1 506360 D 481805 CDS YP_001723469.1 170018515 6068351 506571..507503 1 NC_010468.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 507503 6068351 EcolC_0465 Escherichia coli ATCC 8739 p-hydroxybenzoic acid efflux subunit AaeA YP_001723469.1 506571 D 481805 CDS YP_001723470.1 170018516 6068357 507509..509476 1 NC_010468.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 509476 6068357 EcolC_0466 Escherichia coli ATCC 8739 p-hydroxybenzoic acid efflux subunit AaeB YP_001723470.1 507509 D 481805 CDS YP_001723471.1 170018517 6068363 509568..509840 1 NC_010468.1 KEGG: sbo:SBO_3150 hypothetical protein; hypothetical protein 509840 6068363 EcolC_0467 Escherichia coli ATCC 8739 hypothetical protein YP_001723471.1 509568 D 481805 CDS YP_001723472.1 170018518 6068367 complement(509896..510159) 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_3151 hypothetical protein; hypothetical protein 510159 6068367 EcolC_0468 Escherichia coli ATCC 8739 hypothetical protein YP_001723472.1 509896 R 481805 CDS YP_001723473.1 170018519 6068375 complement(510524..510994) 1 NC_010468.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 510994 6068375 EcolC_0469 Escherichia coli ATCC 8739 arginine repressor YP_001723473.1 510524 R 481805 CDS YP_001723474.1 170018520 6068378 511429..512367 1 NC_010468.1 oxidizes malate to oxaloacetate; malate dehydrogenase 512367 6068378 EcolC_0470 Escherichia coli ATCC 8739 malate dehydrogenase YP_001723474.1 511429 D 481805 CDS YP_001723475.1 170018521 6068387 complement(512430..513497) 1 NC_010468.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sdy:SDY_3411 protease; serine endoprotease 513497 6068387 EcolC_0471 Escherichia coli ATCC 8739 serine endoprotease YP_001723475.1 512430 R 481805 CDS YP_001723476.1 170018522 6068402 complement(513587..514954) 1 NC_010468.1 KEGG: sdy:SDY_3410 serine endoprotease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; serine endoprotease 514954 6068402 EcolC_0472 Escherichia coli ATCC 8739 serine endoprotease YP_001723476.1 513587 R 481805 CDS YP_001723477.1 170018523 6068421 complement(515108..515506) 1 NC_010468.1 PFAM: protein of unknown function DUF1043; KEGG: sbo:SBO_3156 hypothetical protein; cytochrome d ubiquinol oxidase subunit III 515506 6068421 EcolC_0473 Escherichia coli ATCC 8739 cytochrome d ubiquinol oxidase subunit III YP_001723477.1 515108 R 481805 CDS YP_001723478.1 170018524 6068433 515700..516827 1 NC_010468.1 PFAM: AFG1-family ATPase; KEGG: sfv:SFV_3259 hypothetical protein; AFG1 family ATPase 516827 6068433 EcolC_0474 Escherichia coli ATCC 8739 AFG1 family ATPase YP_001723478.1 515700 D 481805 CDS YP_001723479.1 170018525 6068438 517046..517474 1 NC_010468.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 517474 rplM 6068438 rplM Escherichia coli ATCC 8739 50S ribosomal protein L13 YP_001723479.1 517046 D 481805 CDS YP_001723480.1 170018526 6068447 517490..517882 1 NC_010468.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 517882 rpsI 6068447 rpsI Escherichia coli ATCC 8739 30S ribosomal protein S9 YP_001723480.1 517490 D 481805 CDS YP_001723481.1 170018527 6068453 518277..518915 1 NC_010468.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 518915 sspA 6068453 sspA Escherichia coli ATCC 8739 stringent starvation protein A YP_001723481.1 518277 D 481805 CDS YP_001723482.1 170018528 6068466 518921..519418 1 NC_010468.1 PFAM: Stringent starvation protein B; KEGG: sbo:SBO_3161 stringent starvation protein B; ClpXP protease specificity-enhancing factor 519418 6068466 EcolC_0478 Escherichia coli ATCC 8739 ClpXP protease specificity-enhancing factor YP_001723482.1 518921 D 481805 CDS YP_001723483.1 170018529 6068481 complement(519461..520828) 1 NC_010468.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 520828 6068481 EcolC_0479 Escherichia coli ATCC 8739 putative cryptic C4-dicarboxylate transporter DcuD YP_001723483.1 519461 R 481805 CDS YP_001723484.1 170018530 6068485 521208..521999 1 NC_010468.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 521999 6068485 EcolC_0480 Escherichia coli ATCC 8739 transcriptional regulator NanR YP_001723484.1 521208 D 481805 CDS YP_001723485.1 170018531 6068493 522121..523014 1 NC_010468.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 523014 6068493 EcolC_0481 Escherichia coli ATCC 8739 N-acetylneuraminate lyase YP_001723485.1 522121 D 481805 CDS YP_001723486.1 170018532 6068501 523123..524613 1 NC_010468.1 TIGRFAM: sialic acid transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3365 sialic acid transporter; putative sialic acid transporter 524613 6068501 EcolC_0482 Escherichia coli ATCC 8739 putative sialic acid transporter YP_001723486.1 523123 D 481805 CDS YP_001723487.1 170018533 6068512 524661..525350 1 NC_010468.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 525350 6068512 EcolC_0483 Escherichia coli ATCC 8739 N-acetylmannosamine-6-phosphate 2-epimerase YP_001723487.1 524661 D 481805 CDS YP_001723488.1 170018534 6068517 525347..526222 1 NC_010468.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 526222 6068517 EcolC_0484 Escherichia coli ATCC 8739 N-acetylmannosamine kinase YP_001723488.1 525347 D 481805 CDS YP_001723489.1 170018535 6068522 526219..526683 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sfv:SFV_3246 hypothetical protein; hypothetical protein 526683 6068522 EcolC_0485 Escherichia coli ATCC 8739 hypothetical protein YP_001723489.1 526219 D 481805 CDS YP_001723490.1 170018536 6068529 complement(527081..527560) 1 NC_010468.1 PFAM: protein of unknown function DUF1016; KEGG: sdy:SDY_3395 hypothetical protein; hypothetical protein 527560 6068529 EcolC_0486 Escherichia coli ATCC 8739 hypothetical protein YP_001723490.1 527081 R 481805 CDS YP_001723491.1 170018537 6068533 complement(527744..529162) 1 NC_010468.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 529162 gltD 6068533 gltD Escherichia coli ATCC 8739 glutamate synthase subunit beta YP_001723491.1 527744 R 481805 CDS YP_001723492.1 170018538 6068543 complement(529175..533743) 1 NC_010468.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 533743 gltB 6068543 gltB Escherichia coli ATCC 8739 glutamate synthase subunit alpha YP_001723492.1 529175 R 481805 CDS YP_001723493.1 170018539 6068549 534277..535239 1 NC_010468.1 KEGG: sbo:SBO_3171 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; putative radical SAM protein 535239 6068549 EcolC_0489 Escherichia coli ATCC 8739 putative radical SAM protein YP_001723493.1 534277 D 481805 CDS YP_001723494.1 170018540 6068562 535335..537671 1 NC_010468.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 537671 6068562 EcolC_0490 Escherichia coli ATCC 8739 aerobic respiration control sensor protein ArcB YP_001723494.1 535335 D 481805 CDS YP_001723495.1 170018541 6068566 537901..538554 1 NC_010468.1 PFAM: ThiJ/PfpI domain protein; KEGG: sfv:SFV_3239 sigma cross-reacting protein 27A (SCRP-27A); amidotransferase 538554 6068566 EcolC_0491 Escherichia coli ATCC 8739 amidotransferase YP_001723495.1 537901 D 481805 CDS YP_001723496.1 170018542 6068568 538551..539279 1 NC_010468.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 539279 mtgA 6068568 mtgA Escherichia coli ATCC 8739 monofunctional biosynthetic peptidoglycan transglycosylase YP_001723496.1 538551 D 481805 CDS YP_001723497.1 170018543 6068576 complement(539276..539908) 1 NC_010468.1 KEGG: sfx:S3465 hypothetical protein; hypothetical protein 539908 6068576 EcolC_0493 Escherichia coli ATCC 8739 hypothetical protein YP_001723497.1 539276 R 481805 CDS YP_001723498.1 170018544 6068579 complement(540121..540393) 1 NC_010468.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: sdy:SDY_3387 phosphocarrier protein HPr-like NPr; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 540393 6068579 EcolC_0494 Escherichia coli ATCC 8739 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_001723498.1 540121 R 481805 CDS YP_001723499.1 170018545 6068586 complement(540390..541244) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_3177 hypothetical protein; hypothetical protein 541244 6068586 EcolC_0495 Escherichia coli ATCC 8739 hypothetical protein YP_001723499.1 540390 R 481805 CDS YP_001723500.1 170018546 6068592 complement(541290..541781) 1 NC_010468.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sbo:SBO_3178 phosphotransferase system enzyme IIA; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 541781 6068592 EcolC_0496 Escherichia coli ATCC 8739 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_001723500.1 541290 R 481805 CDS YP_001723501.1 170018547 6068600 complement(541899..542186) 1 NC_010468.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 542186 6068600 EcolC_0497 Escherichia coli ATCC 8739 putative sigma(54) modulation protein YP_001723501.1 541899 R 481805 CDS YP_001723502.1 170018548 6068602 complement(542209..543642) 1 NC_010468.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 543642 6068602 EcolC_0498 Escherichia coli ATCC 8739 RNA polymerase factor sigma-54 YP_001723502.1 542209 R 481805 CDS YP_001723503.1 170018549 6068605 complement(543690..544415) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_3382 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein YhbG 544415 6068605 EcolC_0499 Escherichia coli ATCC 8739 putative ABC transporter ATP-binding protein YhbG YP_001723503.1 543690 R 481805 CDS YP_001723504.1 170018550 6068611 complement(544422..544979) 1 NC_010468.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 544979 6068611 EcolC_0500 Escherichia coli ATCC 8739 lipopolysaccharide transport periplasmic protein LptA YP_001723504.1 544422 R 481805 CDS YP_001723505.1 170018551 6068614 complement(544948..545523) 1 NC_010468.1 PFAM: protein of unknown function DUF1239; KEGG: sdy:SDY_3380 hypothetical protein; hypothetical protein 545523 6068614 EcolC_0501 Escherichia coli ATCC 8739 hypothetical protein YP_001723505.1 544948 R 481805 CDS YP_001723506.1 170018552 6068619 complement(545520..546086) 1 NC_010468.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 546086 6068619 EcolC_0502 Escherichia coli ATCC 8739 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_001723506.1 545520 R 481805 CDS YP_001723507.1 170018553 6068624 complement(546107..547093) 1 NC_010468.1 KEGG: sbo:SBO_3185 putative isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); D-arabinose 5-phosphate isomerase 547093 6068624 EcolC_0503 Escherichia coli ATCC 8739 D-arabinose 5-phosphate isomerase YP_001723507.1 546107 R 481805 CDS YP_001723508.1 170018554 6068626 complement(547107..548084) 1 NC_010468.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 548084 6068626 EcolC_0504 Escherichia coli ATCC 8739 putative calcium/sodium:proton antiporter YP_001723508.1 547107 R 481805 CDS YP_001723509.1 170018555 6068628 548294..549103 1 NC_010468.1 ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF 549103 6068628 EcolC_0505 Escherichia coli ATCC 8739 putative ABC transporter ATP-binding protein YrbF YP_001723509.1 548294 D 481805 CDS YP_001723510.1 170018556 6068635 549111..549893 1 NC_010468.1 PFAM: protein of unknown function DUF140; KEGG: sbo:SBO_3188 hypothetical protein; hypothetical protein 549893 6068635 EcolC_0506 Escherichia coli ATCC 8739 hypothetical protein YP_001723510.1 549111 D 481805 CDS YP_001723511.1 170018557 6068641 549898..550449 1 NC_010468.1 PFAM: Mammalian cell entry related domain protein; KEGG: sbo:SBO_3189 hypothetical protein; hypothetical protein 550449 6068641 EcolC_0507 Escherichia coli ATCC 8739 hypothetical protein YP_001723511.1 549898 D 481805 CDS YP_001723512.1 170018558 6068646 550468..551103 1 NC_010468.1 PFAM: toluene tolerance family protein; KEGG: sbo:SBO_3190 hypothetical protein; toluene tolerance family protein 551103 6068646 EcolC_0508 Escherichia coli ATCC 8739 toluene tolerance family protein YP_001723512.1 550468 D 481805 CDS YP_001723513.1 170018559 6068655 551103..551396 1 NC_010468.1 KEGG: sdy:SDY_3372 hypothetical protein; hypothetical protein 551396 6068655 EcolC_0509 Escherichia coli ATCC 8739 hypothetical protein YP_001723513.1 551103 D 481805 CDS YP_001723514.1 170018560 6068659 551556..551810 1 NC_010468.1 PFAM: BolA family protein; KEGG: sdy:SDY_3371 hypothetical protein; BolA family protein 551810 6068659 EcolC_0510 Escherichia coli ATCC 8739 BolA family protein YP_001723514.1 551556 D 481805 CDS YP_001723515.1 170018561 6068666 551865..553124 1 NC_010468.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 553124 6068666 EcolC_0511 Escherichia coli ATCC 8739 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001723515.1 551865 D 481805 CDS YP_001723516.1 170018562 6068669 complement(553172..553450) 1 NC_010468.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 553450 6068669 EcolC_0512 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator Nlp YP_001723516.1 553172 R 481805 CDS YP_001723517.1 170018563 6068675 complement(553679..554650) 1 NC_010468.1 PFAM: Polyprenyl synthetase; KEGG: sbo:SBO_3195 octaprenyl diphosphate synthase; octaprenyl diphosphate synthase 554650 6068675 EcolC_0513 Escherichia coli ATCC 8739 octaprenyl diphosphate synthase YP_001723517.1 553679 R 481805 CDS YP_001723518.1 170018564 6068676 554909..555220 1 NC_010468.1 PFAM: ribosomal protein L21; KEGG: sdy:SDY_3367 50S ribosomal subunit protein L21; 50S ribosomal protein L21 555220 rplU 6068676 rplU Escherichia coli ATCC 8739 50S ribosomal protein L21 YP_001723518.1 554909 D 481805 CDS YP_001723519.1 170018565 6068678 555241..555498 1 NC_010468.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 555498 rpmA 6068678 rpmA Escherichia coli ATCC 8739 50S ribosomal protein L27 YP_001723519.1 555241 D 481805 CDS YP_001723520.1 170018566 6068682 555625..556590 1 NC_010468.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_3198 hypothetical protein; hypothetical protein 556590 6068682 EcolC_0516 Escherichia coli ATCC 8739 hypothetical protein YP_001723520.1 555625 D 481805 CDS YP_001723521.1 170018567 6068686 556606..557778 1 NC_010468.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 557778 obgE 6068686 obgE Escherichia coli ATCC 8739 GTPase ObgE YP_001723521.1 556606 D 481805 CDS YP_001723522.1 170018568 6068695 complement(557964..559397) 1 NC_010468.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 559397 6068695 EcolC_0518 Escherichia coli ATCC 8739 D-alanyl-D-alanine carboxypeptidase YP_001723522.1 557964 R 481805 CDS YP_001723523.1 170018569 6068700 559645..560121 1 NC_010468.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 560121 greA 6068700 greA Escherichia coli ATCC 8739 transcription elongation factor GreA YP_001723523.1 559645 D 481805 CDS YP_001723524.1 170018570 6068704 complement(560277..560570) 1 NC_010468.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 560570 6068704 EcolC_0520 Escherichia coli ATCC 8739 RNA-binding protein YhbY YP_001723524.1 560277 R 481805 CDS YP_001723525.1 170018571 6068716 560696..561325 1 NC_010468.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 561325 rrmJ 6068716 rrmJ Escherichia coli ATCC 8739 23S rRNA methyltransferase J YP_001723525.1 560696 D 481805 CDS YP_001723526.1 170018572 6068720 561425..563359 1 NC_010468.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 563359 hflB 6068720 hflB Escherichia coli ATCC 8739 ATP-dependent metalloprotease YP_001723526.1 561425 D 481805 CDS YP_001723527.1 170018573 6068728 563449..564297 1 NC_010468.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 564297 folP 6068728 folP Escherichia coli ATCC 8739 dihydropteroate synthase YP_001723527.1 563449 D 481805 CDS YP_001723528.1 170018574 6068744 564290..565627 1 NC_010468.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 565627 glmM 6068744 glmM Escherichia coli ATCC 8739 phosphoglucosamine mutase YP_001723528.1 564290 D 481805 CDS YP_001723529.1 170018575 6064457 565855..566187 1 NC_010468.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: ssn:SSON_3323 SecG; preprotein translocase subunit SecG 566187 secG 6064457 secG Escherichia coli ATCC 8739 preprotein translocase subunit SecG YP_001723529.1 565855 D 481805 CDS YP_001723530.1 170018576 6064545 566747..568372 1 NC_010468.1 PFAM: sulfatase; KEGG: sbo:SBO_3209 putative alkaline phosphatase I; sulfatase 568372 6064545 EcolC_0526 Escherichia coli ATCC 8739 sulfatase YP_001723530.1 566747 D 481805 CDS YP_001723531.1 170018577 6064582 complement(568380..569723) 1 NC_010468.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 569723 6064582 EcolC_0527 Escherichia coli ATCC 8739 argininosuccinate synthase YP_001723531.1 568380 R 481805 CDS YP_001723532.2 229597230 6064616 570354..570806 1 NC_010468.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 570806 6064616 EcolC_0528 Escherichia coli ATCC 8739 hypothetical protein YP_001723532.2 570354 D 481805 CDS YP_001723533.1 170018579 6064624 570834..572321 1 NC_010468.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 572321 nusA 6064624 nusA Escherichia coli ATCC 8739 transcription elongation factor NusA YP_001723533.1 570834 D 481805 CDS YP_001723534.1 170018580 6064626 572346..575018 1 NC_010468.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 575018 infB 6064626 infB Escherichia coli ATCC 8739 translation initiation factor IF-2 YP_001723534.1 572346 D 481805 CDS YP_001723535.1 170018581 6064639 575182..575583 1 NC_010468.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 575583 rbfA 6064639 rbfA Escherichia coli ATCC 8739 ribosome-binding factor A YP_001723535.1 575182 D 481805 CDS YP_001723536.1 170018582 6064649 575583..576527 1 NC_010468.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 576527 truB 6064649 truB Escherichia coli ATCC 8739 tRNA pseudouridine synthase B YP_001723536.1 575583 D 481805 CDS YP_001723537.1 170018583 6064664 576676..576945 1 NC_010468.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 576945 rpsO 6064664 rpsO Escherichia coli ATCC 8739 30S ribosomal protein S15 YP_001723537.1 576676 D 481805 CDS YP_001723538.1 170018584 6064672 577192..579327 1 NC_010468.1 KEGG: ssn:SSON_3310 polynucleotide phosphorylase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein; polynucleotide phosphorylase/polyadenylase 579327 6064672 EcolC_0534 Escherichia coli ATCC 8739 polynucleotide phosphorylase/polyadenylase YP_001723538.1 577192 D 481805 CDS YP_001723539.1 170018585 6064686 579436..580320 1 NC_010468.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 580320 6064686 EcolC_0535 Escherichia coli ATCC 8739 lipoprotein NlpI YP_001723539.1 579436 D 481805 CDS YP_001723540.1 170018586 6064695 580500..582389 1 NC_010468.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 582389 6064695 EcolC_0536 Escherichia coli ATCC 8739 ATP-dependent RNA helicase DeaD YP_001723540.1 580500 D 481805 CDS YP_001723541.1 170018587 6064714 582543..583787 1 NC_010468.1 tryptophan transporter of high affinity; tryptophan permease 583787 6064714 EcolC_0537 Escherichia coli ATCC 8739 tryptophan permease YP_001723541.1 582543 D 481805 CDS YP_001723542.1 170018588 6064723 complement(583905..584912) 1 NC_010468.1 PFAM: luciferase family protein; KEGG: sbo:SBO_3222 putative enzyme; hypothetical protein 584912 6064723 EcolC_0538 Escherichia coli ATCC 8739 hypothetical protein YP_001723542.1 583905 R 481805 CDS YP_001723543.1 170018589 6064742 complement(584993..585871) 1 NC_010468.1 PFAM: peptidase U32; KEGG: sdy:SDY_3338 hypothetical protein; peptidase U32 585871 6064742 EcolC_0539 Escherichia coli ATCC 8739 peptidase U32 YP_001723543.1 584993 R 481805 CDS YP_001723544.1 170018590 6064736 complement(585880..586875) 1 NC_010468.1 PFAM: peptidase U32; KEGG: ssn:SSON_3304 putative collagenase; peptidase U32 586875 6064736 EcolC_0540 Escherichia coli ATCC 8739 peptidase U32 YP_001723544.1 585880 R 481805 CDS YP_001723545.1 170018591 6064750 587084..587608 1 NC_010468.1 PFAM: Sterol-binding domain protein; KEGG: sdy:SDY_3336 hypothetical protein; sterol-binding domain-containing protein 587608 6064750 EcolC_0541 Escherichia coli ATCC 8739 sterol-binding domain-containing protein YP_001723545.1 587084 D 481805 CDS YP_001723546.1 170018592 6064776 587602..588105 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_3335 hypothetical protein; N-acetyltransferase GCN5 588105 6064776 EcolC_0542 Escherichia coli ATCC 8739 N-acetyltransferase GCN5 YP_001723546.1 587602 D 481805 CDS YP_001723547.2 229597231 6064799 complement(588092..588394) 1 NC_010468.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: sfv:SFV_3185 hypothetical protein; GIY-YIG nuclease superfamily protein 588394 6064799 EcolC_0543 Escherichia coli ATCC 8739 GIY-YIG nuclease superfamily protein YP_001723547.2 588092 R 481805 CDS YP_001723548.1 170018594 6064786 588445..588888 1 NC_010468.1 KEGG: sfv:SFV_3184 hypothetical protein; hypothetical protein 588888 6064786 EcolC_0544 Escherichia coli ATCC 8739 hypothetical protein YP_001723548.1 588445 D 481805 CDS YP_001723549.1 170018595 6064815 complement(588868..589386) 1 NC_010468.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: sdy:SDY_3332 hypothetical protein; PfpI family intracellular peptidase 589386 6064815 EcolC_0545 Escherichia coli ATCC 8739 PfpI family intracellular peptidase YP_001723549.1 588868 R 481805 CDS YP_001723550.1 170018596 6064832 589514..590149 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_3230 hypothetical protein; NAD-dependent epimerase/dehydratase 590149 6064832 EcolC_0546 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001723550.1 589514 D 481805 CDS YP_001723551.1 170018597 6064855 590222..591262 1 NC_010468.1 PFAM: permease; KEGG: ssn:SSON_3297 hypothetical protein; permease 591262 6064855 EcolC_0547 Escherichia coli ATCC 8739 permease YP_001723551.1 590222 D 481805 CDS YP_001723552.1 170018598 6064852 complement(591376..591951) 1 NC_010468.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: sdy:SDY_3329 putative periplasmic protein; hypothetical protein 591951 6064852 EcolC_0548 Escherichia coli ATCC 8739 hypothetical protein YP_001723552.1 591376 R 481805 CDS YP_001723553.1 170018599 6064895 complement(591961..592551) 1 NC_010468.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 592551 6064895 EcolC_0549 Escherichia coli ATCC 8739 DnaA initiator-associating protein DiaA YP_001723553.1 591961 R 481805 CDS YP_001723554.1 170018600 6064934 complement(592571..592966) 1 NC_010468.1 PFAM: protein of unknown function UPF0102; KEGG: ssn:SSON_3294 hypothetical protein; hypothetical protein 592966 6064934 EcolC_0550 Escherichia coli ATCC 8739 hypothetical protein YP_001723554.1 592571 R 481805 CDS YP_001723555.1 170018601 6064908 complement(592924..594960) 1 NC_010468.1 PFAM: LppC family lipoprotein; KEGG: ssn:SSON_3293 putative glycosylase; LppC family lipoprotein 594960 6064908 EcolC_0551 Escherichia coli ATCC 8739 LppC family lipoprotein YP_001723555.1 592924 R 481805 CDS YP_001723556.1 170018602 6064953 595024..595884 1 NC_010468.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdy:SDY_3325 hypothetical protein; uroporphyrin-III C/tetrapyrrole methyltransferase 595884 6064953 EcolC_0552 Escherichia coli ATCC 8739 uroporphyrin-III C/tetrapyrrole methyltransferase YP_001723556.1 595024 D 481805 CDS YP_001723557.1 170018603 6064969 complement(595927..597018) 1 NC_010468.1 KEGG: sfv:SFV_3175 putative fimbrial protein; putative fimbrial protein 597018 6064969 EcolC_0553 Escherichia coli ATCC 8739 putative fimbrial protein YP_001723557.1 595927 R 481805 CDS YP_001723558.1 170018604 6064985 complement(597029..599545) 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ssn:SSON_3289 putative outer membrane protein; fimbrial biogenesis outer membrane usher protein 599545 6064985 EcolC_0554 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001723558.1 597029 R 481805 CDS YP_001723559.1 170018605 6065003 complement(599575..600270) 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: sfv:SFV_3171 putative chaperone; pili assembly chaperone 600270 6065003 EcolC_0555 Escherichia coli ATCC 8739 pili assembly chaperone YP_001723559.1 599575 R 481805 CDS YP_001723560.1 170018606 6065063 complement(600350..600934) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: esa:ESA_02345 hypothetical protein; fimbrial protein 600934 6065063 EcolC_0556 Escherichia coli ATCC 8739 fimbrial protein YP_001723560.1 600350 R 481805 CDS YP_001723561.1 170018607 6065123 complement(601335..602036) 1 NC_010468.1 PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfx:S3393 putative galactosamine-6-phosphate isomerase; galactosamine-6-phosphate isomerase 602036 6065123 EcolC_0557 Escherichia coli ATCC 8739 galactosamine-6-phosphate isomerase YP_001723561.1 601335 R 481805 CDS YP_001723562.1 170018608 6065098 complement(602091..602882) 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 602882 6065098 EcolC_0558 Escherichia coli ATCC 8739 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_001723562.1 602091 R 481805 CDS YP_001723563.1 170018609 6065140 complement(602872..603675) 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 603675 6065140 EcolC_0559 Escherichia coli ATCC 8739 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_001723563.1 602872 R 481805 CDS YP_001723564.1 170018610 6065179 complement(603714..604190) 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 604190 6065179 EcolC_0560 Escherichia coli ATCC 8739 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_001723564.1 603714 R 481805 CDS YP_001723565.1 170018611 6064391 complement(604357..605217) 1 NC_010468.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 605217 kbaY 6064391 kbaY Escherichia coli ATCC 8739 tagatose-bisphosphate aldolase YP_001723565.1 604357 R 481805 CDS YP_001723566.1 170018612 6064387 complement(605230..606384) 1 NC_010468.1 TIGRFAM: sugar isomerase, AgaS family; PFAM: sugar isomerase (SIS); KEGG: cko:CKO_04536 hypothetical protein; AgaS family sugar isomerase 606384 6064387 EcolC_0562 Escherichia coli ATCC 8739 AgaS family sugar isomerase YP_001723566.1 605230 R 481805 CDS YP_001723567.1 170018613 6064426 complement(606735..607868) 1 NC_010468.1 KEGG: cko:CKO_04535 hypothetical protein; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase 607868 6064426 EcolC_0563 Escherichia coli ATCC 8739 N-acetylglucosamine-6-phosphate deacetylase YP_001723567.1 606735 R 481805 CDS YP_001723568.1 170018614 6064819 complement(607865..608299) 1 NC_010468.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sfx:S3386 putative transport enzyme subunit; PTS system fructose subfamily transporter subunit IIA 608299 6064819 EcolC_0564 Escherichia coli ATCC 8739 PTS system fructose subfamily transporter subunit IIA YP_001723568.1 607865 R 481805 CDS YP_001723569.1 170018615 6067539 complement(608317..609195) 1 NC_010468.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: cko:CKO_04533 hypothetical protein; PTS system mannose/fructose/sorbose family transporter subunit IID 609195 6067539 EcolC_0565 Escherichia coli ATCC 8739 PTS system mannose/fructose/sorbose family transporter subunit IID YP_001723569.1 608317 R 481805 CDS YP_001723570.1 170018616 6067260 complement(609185..609964) 1 NC_010468.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sfx:S3384 N-acetylgalactosameine-specific IIC component 2; PTS system sorbose-specific transporter subunit IIC 609964 6067260 EcolC_0566 Escherichia coli ATCC 8739 PTS system sorbose-specific transporter subunit IIC YP_001723570.1 609185 R 481805 CDS YP_001723571.1 170018617 6065024 complement(609975..610448) 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 610448 6065024 EcolC_0567 Escherichia coli ATCC 8739 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_001723571.1 609975 R 481805 CDS YP_001723572.1 170018618 6067122 complement(610471..611751) 1 NC_010468.1 KEGG: sfx:S3382 putative tagatose 6-phosphate kinase 2; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; D-tagatose-bisphosphate aldolase non-catalytic subunit 611751 6067122 EcolC_0568 Escherichia coli ATCC 8739 D-tagatose-bisphosphate aldolase non-catalytic subunit YP_001723572.1 610471 R 481805 CDS YP_001723573.1 170018619 6066424 612000..612809 1 NC_010468.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 612809 6066424 EcolC_0569 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator AgaR YP_001723573.1 612000 D 481805 CDS YP_001723574.1 170018620 6066631 complement(612864..613328) 1 NC_010468.1 KEGG: ssn:SSON_3287 hypothetical protein; hypothetical protein 613328 6066631 EcolC_0570 Escherichia coli ATCC 8739 hypothetical protein YP_001723574.1 612864 R 481805 CDS YP_001723575.1 170018621 6064966 complement(613328..613663) 1 NC_010468.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 613663 6064966 EcolC_0571 Escherichia coli ATCC 8739 putative regulator PrlF YP_001723575.1 613328 R 481805 CDS YP_001723576.1 170018622 6066119 complement(613812..615383) 1 NC_010468.1 KEGG: sfx:S3380 putative hydrolase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; galactarate dehydratase 615383 6066119 EcolC_0572 Escherichia coli ATCC 8739 galactarate dehydratase YP_001723576.1 613812 R 481805 CDS YP_001723577.1 170018623 6065847 615758..617092 1 NC_010468.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S3379 putative transport protein; d-galactonate transporter 617092 6065847 EcolC_0573 Escherichia coli ATCC 8739 d-galactonate transporter YP_001723577.1 615758 D 481805 CDS YP_001723578.1 170018624 6067595 617108..617878 1 NC_010468.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 617878 6067595 EcolC_0574 Escherichia coli ATCC 8739 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_001723578.1 617108 D 481805 CDS YP_001723579.1 170018625 6064798 617908..618798 1 NC_010468.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 618798 garR 6064798 garR Escherichia coli ATCC 8739 tartronate semialdehyde reductase YP_001723579.1 617908 D 481805 CDS YP_001723580.1 170018626 6065454 618895..620040 1 NC_010468.1 PFAM: glycerate kinase; KEGG: sbo:SBO_2989 hypothetical protein; glycerate kinase 620040 6065454 EcolC_0576 Escherichia coli ATCC 8739 glycerate kinase YP_001723580.1 618895 D 481805 CDS YP_001723581.1 170018627 6065039 complement(622167..622706) 1 NC_010468.1 KEGG: sfv:SFV_3161 hypothetical protein; hypothetical protein 622706 6065039 EcolC_0578 Escherichia coli ATCC 8739 hypothetical protein YP_001723581.1 622167 R 481805 CDS YP_001723582.1 170018628 6066773 complement(622962..623306) 1 NC_010468.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 623306 6066773 EcolC_0579 Escherichia coli ATCC 8739 DNA-binding transcriptional activator TdcR YP_001723582.1 622962 R 481805 CDS YP_001723583.1 170018629 6064915 623495..624433 1 NC_010468.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 624433 6064915 EcolC_0580 Escherichia coli ATCC 8739 DNA-binding transcriptional activator TdcA YP_001723583.1 623495 D 481805 CDS YP_001723584.1 170018630 6066772 624532..625521 1 NC_010468.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 625521 6066772 EcolC_0581 Escherichia coli ATCC 8739 threonine dehydratase YP_001723584.1 624532 D 481805 CDS YP_001723585.1 170018631 6066130 625543..626874 1 NC_010468.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 626874 6066130 EcolC_0582 Escherichia coli ATCC 8739 threonine/serine transporter TdcC YP_001723585.1 625543 D 481805 CDS YP_001723586.1 170018632 6065190 626900..628108 1 NC_010468.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 628108 6065190 EcolC_0583 Escherichia coli ATCC 8739 propionate/acetate kinase YP_001723586.1 626900 D 481805 CDS YP_001723587.1 170018633 6065942 628142..630436 1 NC_010468.1 KEGG: ssn:SSON_3271 probable formate acetyltransferase 3; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; formate acetyltransferase 630436 6065942 EcolC_0584 Escherichia coli ATCC 8739 formate acetyltransferase YP_001723587.1 628142 D 481805 CDS YP_001723588.1 170018634 6066148 630450..630839 1 NC_010468.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sbo:SBO_2978 hypothetical protein; hypothetical protein 630839 6066148 EcolC_0585 Escherichia coli ATCC 8739 hypothetical protein YP_001723588.1 630450 D 481805 CDS YP_001723589.1 170018635 6065775 630911..632275 1 NC_010468.1 KEGG: sfv:SFV_3153 putative L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 632275 6065775 EcolC_0586 Escherichia coli ATCC 8739 L-serine dehydratase 1 YP_001723589.1 630911 D 481805 CDS YP_001723590.1 170018636 6066146 632550..633881 1 NC_010468.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_3268 putative transport system permease protein; serine transporter 633881 6066146 EcolC_0587 Escherichia coli ATCC 8739 serine transporter YP_001723590.1 632550 D 481805 CDS YP_001723591.1 170018637 6066210 633909..635219 1 NC_010468.1 PFAM: protein of unknown function DUF1063; KEGG: sbo:SBO_2975 hypothetical protein; hypothetical protein 635219 6066210 EcolC_0588 Escherichia coli ATCC 8739 hypothetical protein YP_001723591.1 633909 D 481805 CDS YP_001723592.1 170018638 6066290 complement(635353..635517) 1 NC_010468.1 KEGG: sdy:SDY_3299 hypothetical protein; hypothetical protein 635517 6066290 EcolC_0589 Escherichia coli ATCC 8739 hypothetical protein YP_001723592.1 635353 R 481805 CDS YP_001723593.1 170018639 6066413 complement(635540..636241) 1 NC_010468.1 PFAM: Pirin domain protein; KEGG: sbo:SBO_2973 hypothetical protein; pirin domain-containing protein 636241 6066413 EcolC_0590 Escherichia coli ATCC 8739 pirin domain-containing protein YP_001723593.1 635540 R 481805 CDS YP_001723594.1 170018640 6064476 636346..637242 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2972 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 637242 6064476 EcolC_0591 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001723594.1 636346 D 481805 CDS YP_001723595.1 170018641 6065814 complement(637293..637649) 1 NC_010468.1 PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_3263 putative cytochrome; hypothetical protein 637649 6065814 EcolC_0592 Escherichia coli ATCC 8739 hypothetical protein YP_001723595.1 637293 R 481805 CDS YP_001723596.1 170018642 6064700 complement(637890..638255) 1 NC_010468.1 PFAM: protein of unknown function DUF805; KEGG: sbo:SBO_2970 putative cytochrome; hypothetical protein 638255 6064700 EcolC_0593 Escherichia coli ATCC 8739 hypothetical protein YP_001723596.1 637890 R 481805 CDS YP_001723597.1 170018643 6064661 complement(638548..639534) 1 NC_010468.1 KEGG: sdy:SDY_3291 putative transferase; putative transferase 639534 6064661 EcolC_0594 Escherichia coli ATCC 8739 putative transferase YP_001723597.1 638548 R 481805 CDS YP_001723598.1 170018644 6065270 complement(639604..639996) 1 NC_010468.1 PFAM: DoxX family protein; KEGG: sdy:SDY_3290 hypothetical protein; DoxX family protein 639996 6065270 EcolC_0595 Escherichia coli ATCC 8739 DoxX family protein YP_001723598.1 639604 R 481805 CDS YP_001723599.1 170018645 6065272 complement(640182..640481) 1 NC_010468.1 KEGG: sbo:SBO_2967 hypothetical protein; hypothetical protein 640481 6065272 EcolC_0596 Escherichia coli ATCC 8739 hypothetical protein YP_001723599.1 640182 R 481805 CDS YP_001723600.1 170018646 6065165 complement(640471..640875) 1 NC_010468.1 KEGG: sbo:SBO_2966 hypothetical protein; hypothetical protein 640875 6065165 EcolC_0597 Escherichia coli ATCC 8739 hypothetical protein YP_001723600.1 640471 R 481805 CDS YP_001723601.1 170018647 6065769 complement(640878..641183) 1 NC_010468.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_3285 hypothetical protein; hypothetical protein 641183 6065769 EcolC_0598 Escherichia coli ATCC 8739 hypothetical protein YP_001723601.1 640878 R 481805 CDS YP_001723602.1 170018648 6066196 complement(641221..641589) 1 NC_010468.1 PFAM: protein of unknown function DUF1090; KEGG: sbo:SBO_2964 hypothetical protein; hypothetical protein 641589 6066196 EcolC_0599 Escherichia coli ATCC 8739 hypothetical protein YP_001723602.1 641221 R 481805 CDS YP_001723603.1 170018649 6065318 complement(641736..642119) 1 NC_010468.1 KEGG: sdy:SDY_3283 hypothetical protein; hypothetical protein 642119 6065318 EcolC_0600 Escherichia coli ATCC 8739 hypothetical protein YP_001723603.1 641736 R 481805 CDS YP_001723604.1 170018650 6065525 complement(642123..642785) 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: sdy:SDY_3282 hypothetical protein; hypothetical protein 642785 6065525 EcolC_0601 Escherichia coli ATCC 8739 hypothetical protein YP_001723604.1 642123 R 481805 CDS YP_001723605.1 170018651 6065487 complement(643130..643906) 1 NC_010468.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 643906 6065487 EcolC_0602 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor ExuR YP_001723605.1 643130 R 481805 CDS YP_001723606.1 170018652 6067179 644202..644918 1 NC_010468.1 KEGG: ssn:SSON_3252 putative fimbrial protein; hypothetical protein 644918 6067179 EcolC_0603 Escherichia coli ATCC 8739 hypothetical protein YP_001723606.1 644202 D 481805 CDS YP_001723607.1 170018653 6064961 644948..645448 1 NC_010468.1 PFAM: CS1 type fimbrial major subunit; KEGG: sbo:SBO_2959 putative fimbrial subunit; CS1 type fimbrial major subunit 645448 6064961 EcolC_0604 Escherichia coli ATCC 8739 CS1 type fimbrial major subunit YP_001723607.1 644948 D 481805 CDS YP_001723608.1 170018654 6067677 645539..648223 1 NC_010468.1 KEGG: ssn:SSON_3248 outer membrane fimbrial user protein; outer membrane fimbrial user protein 648223 6067677 EcolC_0605 Escherichia coli ATCC 8739 outer membrane fimbrial user protein YP_001723608.1 645539 D 481805 CDS YP_001723609.1 170018655 6065337 648220..649308 1 NC_010468.1 PFAM: CblD family pilus biogenesis initiator protein; KEGG: ssn:SSON_3247 putative minor pilin and initiator; CblD family pilus biogenesis initiator protein 649308 6065337 EcolC_0606 Escherichia coli ATCC 8739 CblD family pilus biogenesis initiator protein YP_001723609.1 648220 D 481805 CDS YP_001723610.1 170018656 6065014 complement(649396..650694) 1 NC_010468.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3134 transport of hexuronates; d-galactonate transporter 650694 6065014 EcolC_0607 Escherichia coli ATCC 8739 d-galactonate transporter YP_001723610.1 649396 R 481805 CDS YP_001723611.1 170018657 6065566 651177..652589 1 NC_010468.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 652589 6065566 EcolC_0608 Escherichia coli ATCC 8739 glucuronate isomerase YP_001723611.1 651177 D 481805 CDS YP_001723612.1 170018658 6066450 652604..654091 1 NC_010468.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: sdy:SDY_3276 altronate hydrolase; altronate dehydratase 654091 6066450 EcolC_0609 Escherichia coli ATCC 8739 altronate dehydratase YP_001723612.1 652604 D 481805 CDS YP_001723613.1 170018659 6066514 654174..654725 1 NC_010468.1 KEGG: ssn:SSON_3243 hypothetical protein; hypothetical protein 654725 6066514 EcolC_0610 Escherichia coli ATCC 8739 hypothetical protein YP_001723613.1 654174 D 481805 CDS YP_001723614.1 170018660 6065978 complement(654730..655974) 1 NC_010468.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 655974 6065978 EcolC_0611 Escherichia coli ATCC 8739 serine/threonine transporter SstT YP_001723614.1 654730 R 481805 CDS YP_001723615.1 170018661 6066829 complement(656373..657338) 1 NC_010468.1 PFAM: Integral membrane protein TerC; KEGG: ssn:SSON_3117 putative transport protein; integral membrane protein TerC 657338 6066829 EcolC_0612 Escherichia coli ATCC 8739 integral membrane protein TerC YP_001723615.1 656373 R 481805 CDS YP_001723616.1 170018662 6066085 complement(657621..658607) 1 NC_010468.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sfv:SFV_3128 hypothetical protein; oxidoreductase domain-containing protein 658607 6066085 EcolC_0613 Escherichia coli ATCC 8739 oxidoreductase domain-containing protein YP_001723616.1 657621 R 481805 CDS YP_001723617.1 170018663 6067752 complement(658686..659369) 1 NC_010468.1 PFAM: protein of unknown function DUF218; KEGG: sbo:SBO_2947 hypothetical protein; hypothetical protein 659369 6067752 EcolC_0614 Escherichia coli ATCC 8739 hypothetical protein YP_001723617.1 658686 R 481805 CDS YP_001723618.1 170018664 6066858 complement(659446..659949) 1 NC_010468.1 PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein; hypothetical protein 659949 6066858 EcolC_0615 Escherichia coli ATCC 8739 hypothetical protein YP_001723618.1 659446 R 481805 CDS YP_001723619.1 170018665 6067315 660034..661170 1 NC_010468.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: sdy:SDY_3267 putative enzyme; rRNA (guanine-N(2)-)-methyltransferase 661170 6067315 EcolC_0616 Escherichia coli ATCC 8739 rRNA (guanine-N(2)-)-methyltransferase YP_001723619.1 660034 D 481805 CDS YP_001723620.1 170018666 6066143 661454..661768 1 NC_010468.1 KEGG: ssn:SSON_3122 hypothetical protein; hypothetical protein 661768 6066143 EcolC_0617 Escherichia coli ATCC 8739 hypothetical protein YP_001723620.1 661454 D 481805 CDS YP_001723621.1 170018667 6065310 661765..662181 1 NC_010468.1 PFAM: helix-turn-helix domain protein; KEGG: sfv:SFV_3123 hypothetical protein; helix-turn-helix domain-containing protein 662181 6065310 EcolC_0618 Escherichia coli ATCC 8739 helix-turn-helix domain-containing protein YP_001723621.1 661765 D 481805 CDS YP_001723622.1 170018668 6064806 complement(662226..664244) 1 NC_010468.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_3124 putative NADPH dehydrogenase; NADH:flavin oxidoreductase 664244 6064806 EcolC_0619 Escherichia coli ATCC 8739 NADH:flavin oxidoreductase YP_001723622.1 662226 R 481805 CDS YP_001723623.1 170018669 6064679 complement(664670..667021) 1 NC_010468.1 KEGG: sfl:SF3120 putative isomerase; putative glycosyl hydrolase 667021 6064679 EcolC_0620 Escherichia coli ATCC 8739 putative glycosyl hydrolase YP_001723623.1 664670 R 481805 CDS YP_001723624.1 170018670 6066855 complement(667038..668108) 1 NC_010468.1 KEGG: ssn:SSON_3126 hypothetical protein; hypothetical protein 668108 6066855 EcolC_0621 Escherichia coli ATCC 8739 hypothetical protein YP_001723624.1 667038 R 481805 CDS YP_001723625.1 170018671 6066512 complement(668242..669675) 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_2937 putative oxidoreductase; amino acid permease-associated protein 669675 6066512 EcolC_0622 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001723625.1 668242 R 481805 CDS YP_001723626.1 170018672 6065534 complement(669738..670187) 1 NC_010468.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 670187 ebgC 6065534 ebgC Escherichia coli ATCC 8739 cryptic beta-D-galactosidase subunit beta YP_001723626.1 669738 R 481805 CDS YP_001723627.1 170018673 6064632 complement(670184..673276) 1 NC_010468.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 673276 ebgA 6064632 ebgA Escherichia coli ATCC 8739 cryptic beta-D-galactosidase subunit alpha YP_001723627.1 670184 R 481805 CDS YP_001723628.1 170018674 6065424 complement(673460..674443) 1 NC_010468.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sdy:SDY_3259 regulator of ebg operon; DNA-binding transcriptional repressor EbgR 674443 6065424 EcolC_0625 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor EbgR YP_001723628.1 673460 R 481805 CDS YP_001723629.1 170018675 6066562 674662..674994 1 NC_010468.1 PFAM: t-RNA-binding domain protein; KEGG: sbo:SBO_2933 putative tRNA synthetase; hypothetical protein 674994 6066562 EcolC_0626 Escherichia coli ATCC 8739 hypothetical protein YP_001723629.1 674662 D 481805 CDS YP_001723630.1 170018676 6066715 complement(675036..676325) 1 NC_010468.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 676325 6066715 EcolC_0627 Escherichia coli ATCC 8739 putrescine--2-oxoglutarate aminotransferase YP_001723630.1 675036 R 481805 CDS YP_001723631.1 170018677 6065695 676833..678353 1 NC_010468.1 KEGG: ssn:SSON_3210 aerotaxis sensor receptor, flavoprotein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor 678353 6065695 EcolC_0628 Escherichia coli ATCC 8739 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor YP_001723631.1 676833 D 481805 CDS YP_001723632.1 170018678 6067083 complement(678507..679130) 1 NC_010468.1 PFAM: transcriptional regulator PadR family protein; KEGG: sbo:SBO_2930 hypothetical protein; PadR-like family transcriptional regulator 679130 6067083 EcolC_0629 Escherichia coli ATCC 8739 PadR-like family transcriptional regulator YP_001723632.1 678507 R 481805 CDS YP_001723633.1 170018679 6066045 679418..680182 1 NC_010468.1 PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: sbo:SBO_2929 hypothetical protein; FAD-binding 9 siderophore-interacting domain-containing protein 680182 6066045 EcolC_0630 Escherichia coli ATCC 8739 FAD-binding 9 siderophore-interacting domain-containing protein YP_001723633.1 679418 D 481805 CDS YP_001723634.1 170018680 6065957 680436..680942 1 NC_010468.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: sbo:SBO_2927 hypothetical protein; G/U mismatch-specific DNA glycosylase 680942 6065957 EcolC_0631 Escherichia coli ATCC 8739 G/U mismatch-specific DNA glycosylase YP_001723634.1 680436 D 481805 CDS YP_001723635.1 170018681 6066445 complement(681021..682862) 1 NC_010468.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 682862 6066445 EcolC_0632 Escherichia coli ATCC 8739 RNA polymerase sigma factor RpoD YP_001723635.1 681021 R 481805 CDS YP_001723636.1 170018682 6066446 complement(683057..684802) 1 NC_010468.1 synthesizes RNA primers at the replication forks; DNA primase 684802 dnaG 6066446 dnaG Escherichia coli ATCC 8739 DNA primase YP_001723636.1 683057 R 481805 CDS YP_001723637.1 170018683 6066911 complement(684913..685128) 1 NC_010468.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 685128 rpsU 6066911 rpsU Escherichia coli ATCC 8739 30S ribosomal protein S21 YP_001723637.1 684913 R 481805 CDS YP_001723638.1 170018684 6065430 685365..686378 1 NC_010468.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 686378 6065430 EcolC_0635 Escherichia coli ATCC 8739 putative DNA-binding/iron metalloprotein/AP endonuclease YP_001723638.1 685365 D 481805 CDS YP_001723639.1 170018685 6064613 complement(686421..687884) 1 NC_010468.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: sfv:SFV_3103 hypothetical protein; anion transporter 687884 6064613 EcolC_0636 Escherichia coli ATCC 8739 anion transporter YP_001723639.1 686421 R 481805 CDS YP_001723640.1 170018686 6064610 complement(687932..688537) 1 NC_010468.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 688537 6064610 EcolC_0637 Escherichia coli ATCC 8739 L(+)-tartrate dehydratase subunit beta YP_001723640.1 687932 R 481805 CDS YP_001723641.1 170018687 6066378 complement(688534..689445) 1 NC_010468.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 689445 6066378 EcolC_0638 Escherichia coli ATCC 8739 tartrate dehydratase subunit alpha YP_001723641.1 688534 R 481805 CDS YP_001723642.1 170018688 6065773 689652..690584 1 NC_010468.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 690584 6065773 EcolC_0639 Escherichia coli ATCC 8739 transcriptional activator TtdR YP_001723642.1 689652 D 481805 CDS YP_001723643.1 170018689 6066272 complement(690597..691214) 1 NC_010468.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 691214 6066272 EcolC_0640 Escherichia coli ATCC 8739 putative glycerol-3-phosphate acyltransferase PlsY YP_001723643.1 690597 R 481805 CDS YP_001723644.1 170018690 6065330 691319..691687 1 NC_010468.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 691687 folB 6065330 folB Escherichia coli ATCC 8739 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_001723644.1 691319 D 481805 CDS YP_001723645.1 170018691 6065744 691777..692598 1 NC_010468.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 692598 6065744 EcolC_0642 Escherichia coli ATCC 8739 undecaprenyl pyrophosphate phosphatase YP_001723645.1 691777 D 481805 CDS YP_001723646.1 170018692 6067127 complement(692779..694017) 1 NC_010468.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 694017 cca 6067127 cca Escherichia coli ATCC 8739 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_001723646.1 692779 R 481805 CDS YP_001723647.1 170018693 6065678 complement(694081..694701) 1 NC_010468.1 SMART: SH3 domain protein; KEGG: ssn:SSON_3192 hypothetical protein; putative signal transduction protein 694701 6065678 EcolC_0644 Escherichia coli ATCC 8739 putative signal transduction protein YP_001723647.1 694081 R 481805 CDS YP_001723648.1 170018694 6065504 694943..696244 1 NC_010468.1 PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: sdy:SDY_3237 hypothetical protein; adenylate cyclase 696244 6065504 EcolC_0645 Escherichia coli ATCC 8739 adenylate cyclase YP_001723648.1 694943 D 481805 CDS YP_001723649.1 170018695 6066688 696267..699107 1 NC_010468.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 699107 6066688 EcolC_0646 Escherichia coli ATCC 8739 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001723649.1 696267 D 481805 CDS YP_001723650.1 170018696 6066685 699155..700588 1 NC_010468.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 700588 6066685 EcolC_0647 Escherichia coli ATCC 8739 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_001723650.1 699155 D 481805 CDS YP_001723651.1 170018697 6065681 complement(701381..703042) 1 NC_010468.1 PFAM: band 7 protein; KEGG: ssn:SSON_3188 hypothetical protein; hypothetical protein 703042 6065681 EcolC_0648 Escherichia coli ATCC 8739 hypothetical protein YP_001723651.1 701381 R 481805 CDS YP_001723652.1 170018698 6067076 complement(703069..703698) 1 NC_010468.1 PFAM: protein of unknown function DUF1449; KEGG: ssn:SSON_3187 putative oxidoreductase; hypothetical protein 703698 6067076 EcolC_0649 Escherichia coli ATCC 8739 hypothetical protein YP_001723652.1 703069 R 481805 CDS YP_001723653.1 170018699 6065111 703967..704167 1 NC_010468.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 704167 6065111 EcolC_0650 Escherichia coli ATCC 8739 glycogen synthesis protein GlgS YP_001723653.1 703967 D 481805 CDS YP_001723654.1 170018700 6064822 complement(704210..705241) 1 NC_010468.1 KEGG: ssn:SSON_3184 hypothetical protein; hypothetical protein 705241 6064822 EcolC_0651 Escherichia coli ATCC 8739 hypothetical protein YP_001723654.1 704210 R 481805 CDS YP_001723655.1 170018701 6066235 complement(705276..706025) 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_3183 hypothetical protein; pili assembly chaperone 706025 6066235 EcolC_0652 Escherichia coli ATCC 8739 pili assembly chaperone YP_001723655.1 705276 R 481805 CDS YP_001723656.1 170018702 6064803 complement(706047..708545) 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB3895 outer membrane fimbrial usher porin; fimbrial biogenesis outer membrane usher protein 708545 6064803 EcolC_0653 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001723656.1 706047 R 481805 CDS YP_001723657.1 170018703 6066382 complement(708605..709156) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_3180 putative fimbrial-like protein; putative fimbrial protein 709156 6066382 EcolC_0654 Escherichia coli ATCC 8739 putative fimbrial protein YP_001723657.1 708605 R 481805 CDS YP_001723658.1 170018704 6066066 complement(709440..709730) 1 NC_010468.1 PFAM: protein of unknown function DUF526; KEGG: sfv:SFV_3086 hypothetical protein; hypothetical protein 709730 6066066 EcolC_0655 Escherichia coli ATCC 8739 hypothetical protein YP_001723658.1 709440 R 481805 CDS YP_001723659.1 170018705 6066613 710104..710757 1 NC_010468.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 710757 ribB 6066613 ribB Escherichia coli ATCC 8739 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001723659.1 710104 D 481805 CDS YP_001723660.1 170018706 6067100 711019..711189 1 NC_010468.1 KEGG: cko:CKO_04433 hypothetical protein; hypothetical protein 711189 6067100 EcolC_0657 Escherichia coli ATCC 8739 hypothetical protein YP_001723660.1 711019 D 481805 CDS YP_001723661.1 170018707 6067515 complement(711247..712020) 1 NC_010468.1 PFAM: zinc/iron permease; KEGG: ssn:SSON_3177 hypothetical protein; zinc transporter ZupT 712020 6067515 EcolC_0658 Escherichia coli ATCC 8739 zinc transporter ZupT YP_001723661.1 711247 R 481805 CDS YP_001723662.1 170018708 6067563 712136..712951 1 NC_010468.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 712951 6067563 EcolC_0659 Escherichia coli ATCC 8739 hypothetical protein YP_001723662.1 712136 D 481805 CDS YP_001723663.1 170018709 6065516 complement(712989..714149) 1 NC_010468.1 PFAM: glutathionylspermidine synthase; KEGG: sfv:SFV_3082 putative synthetase/amidase; glutathionylspermidine synthase 714149 6065516 EcolC_0660 Escherichia coli ATCC 8739 glutathionylspermidine synthase YP_001723663.1 712989 R 481805 CDS YP_001723664.1 170018710 6065168 complement(714155..714826) 1 NC_010468.1 KEGG: ssn:SSON_3174 hypothetical protein; hypothetical protein 714826 6065168 EcolC_0661 Escherichia coli ATCC 8739 hypothetical protein YP_001723664.1 714155 R 481805 CDS YP_001723665.1 170018711 6065508 complement(714974..716455) 1 NC_010468.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 716455 tolC 6065508 tolC Escherichia coli ATCC 8739 outer membrane channel protein YP_001723665.1 714974 R 481805 CDS YP_001723666.1 170018712 6066990 716660..717289 1 NC_010468.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 717289 nudF 6066990 nudF Escherichia coli ATCC 8739 ADP-ribose pyrophosphatase NudF YP_001723666.1 716660 D 481805 CDS YP_001723667.1 170018713 6066331 717290..717712 1 NC_010468.1 PFAM: protein of unknown function DUF1249; KEGG: ssn:SSON_3171 putative enzyme; hypothetical protein 717712 6066331 EcolC_0664 Escherichia coli ATCC 8739 hypothetical protein YP_001723667.1 717290 D 481805 CDS YP_001723668.1 170018714 6066254 717737..718561 1 NC_010468.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: sdy:SDY_3208 regulator of LacZ; cyclic 3',5'-adenosine monophosphate phosphodiesterase 718561 6066254 EcolC_0665 Escherichia coli ATCC 8739 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_001723668.1 717737 D 481805 CDS YP_001723669.1 170018715 6065076 718561..719142 1 NC_010468.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 719142 6065076 EcolC_0666 Escherichia coli ATCC 8739 esterase YqiA YP_001723669.1 718561 D 481805 CDS YP_001723670.1 170018716 6066334 719171..721063 1 NC_010468.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 721063 6066334 EcolC_0667 Escherichia coli ATCC 8739 DNA topoisomerase IV subunit B YP_001723670.1 719171 D 481805 CDS YP_001723671.1 170018717 6067291 complement(721111..721425) 1 NC_010468.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sbo:SBO_2887 hypothetical protein; antibiotic biosynthesis monooxygenase 721425 6067291 EcolC_0668 Escherichia coli ATCC 8739 antibiotic biosynthesis monooxygenase YP_001723671.1 721111 R 481805 CDS YP_001723672.1 170018718 6065951 complement(721456..722037) 1 NC_010468.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: sbo:SBO_2886 modulator of drug activity B; NAD(P)H dehydrogenase (quinone) 722037 6065951 EcolC_0669 Escherichia coli ATCC 8739 NAD(P)H dehydrogenase (quinone) YP_001723672.1 721456 R 481805 CDS YP_001723673.1 170018719 6067668 722356..722688 1 NC_010468.1 KEGG: sfx:S3272 hypothetical protein; hypothetical protein 722688 6067668 EcolC_0670 Escherichia coli ATCC 8739 hypothetical protein YP_001723673.1 722356 D 481805 CDS YP_001723674.1 170018720 6066011 complement(722734..724083) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_3165 quorum sensing regulator C; sensor protein QseC 724083 6066011 EcolC_0671 Escherichia coli ATCC 8739 sensor protein QseC YP_001723674.1 722734 R 481805 CDS YP_001723675.1 170018721 6064844 complement(724080..724739) 1 NC_010468.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 724739 6064844 EcolC_0672 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator QseB YP_001723675.1 724080 R 481805 CDS YP_001723676.1 170018722 6064847 724891..725283 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3215 hypothetical protein; hypothetical protein 725283 6064847 EcolC_0673 Escherichia coli ATCC 8739 hypothetical protein YP_001723676.1 724891 D 481805 CDS YP_001723677.1 170018723 6066538 725336..725818 1 NC_010468.1 PFAM: transcription activator effector binding; KEGG: ssn:SSON_3162 hypothetical protein; transcription activator effector binding 725818 6066538 EcolC_0674 Escherichia coli ATCC 8739 transcription activator effector binding YP_001723677.1 725336 D 481805 CDS YP_001723678.1 170018724 6065665 726023..726319 1 NC_010468.1 KEGG: yps:YPTB3124 hypothetical protein; hypothetical protein 726319 6065665 EcolC_0675 Escherichia coli ATCC 8739 hypothetical protein YP_001723678.1 726023 D 481805 CDS YP_001723679.1 170018725 6066535 726321..726716 1 NC_010468.1 SMART: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_0889 putative transcriptional regulator; XRE family transcriptional regulator 726716 6066535 EcolC_0676 Escherichia coli ATCC 8739 XRE family transcriptional regulator YP_001723679.1 726321 D 481805 CDS YP_001723680.1 170018726 6065662 726849..728456 1 NC_010468.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein 728456 6065662 EcolC_0677 Escherichia coli ATCC 8739 putative binding protein YP_001723680.1 726849 D 481805 CDS YP_001723681.1 170018727 6065587 728594..730852 1 NC_010468.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 730852 6065587 EcolC_0678 Escherichia coli ATCC 8739 DNA topoisomerase IV subunit A YP_001723681.1 728594 D 481805 CDS YP_001723682.1 170018728 6067221 731086..731823 1 NC_010468.1 KEGG: sbo:SBO_2880 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 731823 6067221 EcolC_0679 Escherichia coli ATCC 8739 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001723682.1 731086 D 481805 CDS YP_001723683.1 170018729 6067184 731898..733310 1 NC_010468.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sfv:SFV_3066 suppressor of FtsI; repressor protein for FtsI 733310 6067184 EcolC_0680 Escherichia coli ATCC 8739 repressor protein for FtsI YP_001723683.1 731898 D 481805 CDS YP_001723684.1 170018730 6067468 733421..735640 1 NC_010468.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sbo:SBO_2878 Fe-S oxidoreductase; hypothetical protein 735640 6067468 EcolC_0681 Escherichia coli ATCC 8739 hypothetical protein YP_001723684.1 733421 D 481805 CDS YP_001723685.1 170018731 6066460 complement(735683..735940) 1 NC_010468.1 KEGG: sbo:SBO_3008 hypothetical protein; putative outer membrane lipoprotein 735940 6066460 EcolC_0682 Escherichia coli ATCC 8739 putative outer membrane lipoprotein YP_001723685.1 735683 R 481805 CDS YP_001723686.1 170018732 6065593 complement(735991..736917) 1 NC_010468.1 KEGG: sbo:SBO_3007 hypothetical protein; hypothetical protein 736917 6065593 EcolC_0683 Escherichia coli ATCC 8739 hypothetical protein YP_001723686.1 735991 R 481805 CDS YP_001723687.1 170018733 6066814 complement(737117..737944) 1 NC_010468.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 737944 dkgA 6066814 dkgA Escherichia coli ATCC 8739 2,5-diketo-D-gluconate reductase A YP_001723687.1 737117 R 481805 CDS YP_001723688.1 170018734 6064684 complement(738049..739212) 1 NC_010468.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sfv:SFV_3060 putative oxidoreductase; iron-containing alcohol dehydrogenase 739212 6064684 EcolC_0685 Escherichia coli ATCC 8739 iron-containing alcohol dehydrogenase YP_001723688.1 738049 R 481805 CDS YP_001723689.1 170018735 6066680 739349..740305 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: sbo:SBO_3005 putative AraC-type regulatory protein; AraC family transcriptional regulator 740305 6066680 EcolC_0686 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001723689.1 739349 D 481805 CDS YP_001723690.1 170018736 6066805 complement(740345..741004) 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_3152 hypothetical protein; hypothetical protein 741004 6066805 EcolC_0687 Escherichia coli ATCC 8739 hypothetical protein YP_001723690.1 740345 R 481805 CDS YP_001723691.1 170018737 6065155 complement(741144..742331) 1 NC_010468.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 742331 6065155 EcolC_0688 Escherichia coli ATCC 8739 cystathionine beta-lyase YP_001723691.1 741144 R 481805 CDS YP_001723692.1 170018738 6066459 742583..743317 1 NC_010468.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 743317 6066459 EcolC_0689 Escherichia coli ATCC 8739 biopolymer transport protein ExbB YP_001723692.1 742583 D 481805 CDS YP_001723693.1 170018739 6066470 743324..743749 1 NC_010468.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 743749 6066470 EcolC_0690 Escherichia coli ATCC 8739 biopolymer transport protein ExbD YP_001723693.1 743324 D 481805 CDS YP_001723694.1 170018740 6065217 complement(744021..744905) 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbo:SBO_2997 putative oxidoreductase; oxidoreductase 744905 6065217 EcolC_0691 Escherichia coli ATCC 8739 oxidoreductase YP_001723694.1 744021 R 481805 CDS YP_001723695.1 170018741 6066339 745096..745590 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2996 hypothetical protein; hypothetical protein 745590 6066339 EcolC_0692 Escherichia coli ATCC 8739 hypothetical protein YP_001723695.1 745096 D 481805 CDS YP_001723696.1 170018742 6065625 complement(745630..746670) 1 NC_010468.1 PFAM: aldo/keto reductase; KEGG: sfv:SFV_3053 putative reductase; aldo-keto reductase 746670 6065625 EcolC_0693 Escherichia coli ATCC 8739 aldo-keto reductase YP_001723696.1 745630 R 481805 CDS YP_001723697.1 170018743 6064682 747831..748118 1 NC_010468.1 KEGG: sdy:SDY_3075 hypothetical protein; hypothetical protein 748118 6064682 EcolC_0695 Escherichia coli ATCC 8739 hypothetical protein YP_001723697.1 747831 D 481805 CDS YP_001723698.1 170018744 6065128 748307..749425 1 NC_010468.1 involved in hydrogen uptake; hydrogenase 2 small subunit 749425 6065128 EcolC_0696 Escherichia coli ATCC 8739 hydrogenase 2 small subunit YP_001723698.1 748307 D 481805 CDS YP_001723699.1 170018745 6065323 749428..750414 1 NC_010468.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 750414 6065323 EcolC_0697 Escherichia coli ATCC 8739 hydrogenase 2 protein HybA YP_001723699.1 749428 D 481805 CDS YP_001723700.1 170018746 6065345 750404..751582 1 NC_010468.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 751582 6065345 EcolC_0698 Escherichia coli ATCC 8739 putative hydrogenase 2 b cytochrome subunit YP_001723700.1 750404 D 481805 CDS YP_001723701.1 170018747 6065733 751579..753282 1 NC_010468.1 involved in hydrogen uptake; hydrogenase 2 large subunit 753282 6065733 EcolC_0699 Escherichia coli ATCC 8739 hydrogenase 2 large subunit YP_001723701.1 751579 D 481805 CDS YP_001723702.1 170018748 6066456 753282..753776 1 NC_010468.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 753776 hybD 6066456 hybD Escherichia coli ATCC 8739 hydrogenase 2 maturation endopeptidase YP_001723702.1 753282 D 481805 CDS YP_001723703.1 170018749 6067105 753769..754257 1 NC_010468.1 KEGG: sbo:SBO_2871 HybE; hydrogenase 2-specific chaperone 754257 6067105 EcolC_0701 Escherichia coli ATCC 8739 hydrogenase 2-specific chaperone YP_001723703.1 753769 D 481805 CDS YP_001723704.1 170018750 6066600 754250..754591 1 NC_010468.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 754591 6066600 EcolC_0702 Escherichia coli ATCC 8739 hydrogenase nickel incorporation protein HybF YP_001723704.1 754250 D 481805 CDS YP_001723705.1 170018751 6066575 754604..754852 1 NC_010468.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: sdy:SDY_3083 hydrogenase-2 operon protein; hydrogenase 2 accessory protein HypG 754852 6066575 EcolC_0703 Escherichia coli ATCC 8739 hydrogenase 2 accessory protein HypG YP_001723705.1 754604 D 481805 CDS YP_001723706.1 170018752 6066681 complement(754975..755841) 1 NC_010468.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 755841 6066681 EcolC_0704 Escherichia coli ATCC 8739 putative glutathione S-transferase YghU YP_001723706.1 754975 R 481805 CDS YP_001723707.1 170018753 6066727 756046..757905 1 NC_010468.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 757905 6066727 EcolC_0705 Escherichia coli ATCC 8739 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_001723707.1 756046 D 481805 CDS YP_001723708.1 170018754 6065079 758197..759696 1 NC_010468.1 PFAM: phosphate transporter; KEGG: ssn:SSON_3132 low-affinity phosphate transport; phosphate transporter 759696 6065079 EcolC_0706 Escherichia coli ATCC 8739 phosphate transporter YP_001723708.1 758197 D 481805 CDS YP_001723709.1 170018755 6066660 complement(759745..760437) 1 NC_010468.1 KEGG: sfx:S3234 hypothetical protein; hypothetical protein 760437 6066660 EcolC_0707 Escherichia coli ATCC 8739 hypothetical protein YP_001723709.1 759745 R 481805 CDS YP_001723710.1 170018756 6065878 760626..761324 1 NC_010468.1 KEGG: ssn:SSON_3219 hypothetical protein; hypothetical protein 761324 6065878 EcolC_0708 Escherichia coli ATCC 8739 hypothetical protein YP_001723710.1 760626 D 481805 CDS YP_001723711.1 170018757 6066476 761356..762114 1 NC_010468.1 KEGG: ssn:SSON_3220 hypothetical protein; hypothetical protein 762114 6066476 EcolC_0709 Escherichia coli ATCC 8739 hypothetical protein YP_001723711.1 761356 D 481805 CDS YP_001723712.1 170018758 6065882 762160..763509 1 NC_010468.1 PFAM: polysaccharide biosynthesis protein; KEGG: sfx:S3231 hypothetical protein; polysaccharide biosynthesis protein 763509 6065882 EcolC_0710 Escherichia coli ATCC 8739 polysaccharide biosynthesis protein YP_001723712.1 762160 D 481805 CDS YP_001723713.1 170018759 6065989 763509..764333 1 NC_010468.1 KEGG: sfx:S3230 hypothetical protein; hypothetical protein 764333 6065989 EcolC_0711 Escherichia coli ATCC 8739 hypothetical protein YP_001723713.1 763509 D 481805 CDS YP_001723714.1 170018760 6066597 764345..764905 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sfx:S3229 hypothetical protein; hypothetical protein 764905 6066597 EcolC_0712 Escherichia coli ATCC 8739 hypothetical protein YP_001723714.1 764345 D 481805 CDS YP_001723715.1 170018761 6067664 764936..766006 1 NC_010468.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sfx:S3228 hypothetical protein; YjgP/YjgQ family permease 766006 6067664 EcolC_0713 Escherichia coli ATCC 8739 YjgP/YjgQ family permease YP_001723715.1 764936 D 481805 CDS YP_001723716.1 170018762 6066385 766003..767082 1 NC_010468.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sfx:S3227 hypothetical protein; YjgP/YjgQ family permease 767082 6066385 EcolC_0714 Escherichia coli ATCC 8739 YjgP/YjgQ family permease YP_001723716.1 766003 D 481805 CDS YP_001723717.1 170018763 6066628 complement(767117..768289) 1 NC_010468.1 PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: sfx:S3226 putative class II aminotransferase; 8-amino-7-oxononanoate synthase 768289 6066628 EcolC_0715 Escherichia coli ATCC 8739 8-amino-7-oxononanoate synthase YP_001723717.1 767117 R 481805 CDS YP_001723718.1 170018764 6067238 complement(768289..768537) 1 NC_010468.1 PFAM: phosphopantetheine-binding; KEGG: sfx:S3224 hypothetical protein; phosphopantetheine-binding protein 768537 6067238 EcolC_0716 Escherichia coli ATCC 8739 phosphopantetheine-binding protein YP_001723718.1 768289 R 481805 CDS YP_001723719.1 170018765 6066081 complement(768569..769483) 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: sfx:S3223 hypothetical protein; NAD-dependent epimerase/dehydratase 769483 6066081 EcolC_0717 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001723719.1 768569 R 481805 CDS YP_001723720.1 170018766 6065986 complement(769480..771201) 1 NC_010468.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 771201 6065986 EcolC_0718 Escherichia coli ATCC 8739 acyl-CoA synthetase YP_001723720.1 769480 R 481805 CDS YP_001723721.1 170018767 6065828 771578..772720 1 NC_010468.1 KEGG: sfv:SFV_3037 hypothetical protein; hypothetical protein 772720 6065828 EcolC_0719 Escherichia coli ATCC 8739 hypothetical protein YP_001723721.1 771578 D 481805 CDS YP_001723722.1 170018768 6064944 complement(772727..773491) 1 NC_010468.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfx:S3220 transcriptional activator for glc operon; DNA-binding transcriptional regulator GlcC 773491 6064944 EcolC_0720 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator GlcC YP_001723722.1 772727 R 481805 CDS YP_001723723.1 170018769 6065831 773742..775241 1 NC_010468.1 TIGRFAM: glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein; KEGG: psa:PST_0431 glycolate oxidase, subunit GlcD; glycolate oxidase subunit GlcD 775241 6065831 EcolC_0721 Escherichia coli ATCC 8739 glycolate oxidase subunit GlcD YP_001723723.1 773742 D 481805 CDS YP_001723724.1 170018770 6066610 775241..776293 1 NC_010468.1 PFAM: FAD linked oxidase domain protein; KEGG: psa:PST_0432 glycolate oxidase, subunit GlcE; glycolate oxidase FAD binding subunit 776293 glcE 6066610 glcE Escherichia coli ATCC 8739 glycolate oxidase FAD binding subunit YP_001723724.1 775241 D 481805 CDS YP_001723725.1 170018771 6065809 776304..777527 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: pmy:Pmen_0201 protein of unknown function DUF224, cysteine-rich region domain protein; glycolate oxidase iron-sulfur subunit 777527 glcF 6065809 glcF Escherichia coli ATCC 8739 glycolate oxidase iron-sulfur subunit YP_001723725.1 776304 D 481805 CDS YP_001723726.1 170018772 6064943 777532..777936 1 NC_010468.1 PFAM: protein of unknown function DUF336; KEGG: sfv:SFV_3032 hypothetical protein; hypothetical protein 777936 6064943 EcolC_0724 Escherichia coli ATCC 8739 hypothetical protein YP_001723726.1 777532 D 481805 CDS YP_001723727.1 170018773 6066053 777958..780129 1 NC_010468.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 780129 6066053 EcolC_0725 Escherichia coli ATCC 8739 malate synthase G YP_001723727.1 777958 D 481805 CDS YP_001723728.1 170018774 6066074 780484..782166 1 NC_010468.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sfv:SFV_3030 putative permease; glycolate transporter 782166 6066074 EcolC_0726 Escherichia coli ATCC 8739 glycolate transporter YP_001723728.1 780484 D 481805 CDS YP_001723729.1 170018775 6064976 782651..783082 1 NC_010468.1 KEGG: ter:Tery_2591 cadherin; hypothetical protein 783082 6064976 EcolC_0727 Escherichia coli ATCC 8739 hypothetical protein YP_001723729.1 782651 D 481805 CDS YP_001723730.1 170018776 6067593 783110..783409 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 783409 6067593 EcolC_0728 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001723730.1 783110 D 481805 CDS YP_001723731.1 170018777 6067680 783406..784272 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 784272 6067680 EcolC_0729 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001723731.1 783406 D 481805 CDS YP_001723732.1 170018778 6065751 complement(784269..784913) 1 NC_010468.1 PFAM: HMG-I and HMG-Y DNA-binding domain protein; regulatory protein TetR; KEGG: kpn:KPN_02440 putative bacterial regulatory protein, TetR; TetR family transcriptional regulator 784913 6065751 EcolC_0730 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001723732.1 784269 R 481805 CDS YP_001723733.1 170018779 6064770 complement(785534..786337) 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family; integrase catalytic subunit 786337 6064770 EcolC_0732 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001723733.1 785534 R 481805 CDS YP_001723734.1 170018780 6065591 complement(786385..786669) 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 786669 6065591 EcolC_0733 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001723734.1 786385 R 481805 CDS YP_001723735.1 170018781 6068703 complement(786762..788042) 1 NC_010468.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: kpn:KPN_pKPN3p05958 secondary glycine betaine transporter BetU; choline/carnitine/betaine transporter 788042 6068703 EcolC_0734 Escherichia coli ATCC 8739 choline/carnitine/betaine transporter YP_001723735.1 786762 R 481805 CDS YP_001723736.1 170018782 6066823 complement(788190..789008) 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2; integrase catalytic subunit 789008 6066823 EcolC_0735 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001723736.1 788190 R 481805 CDS YP_001723737.1 170018783 6067024 complement(789093..790244) 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30; integrase catalytic subunit 790244 6067024 EcolC_0736 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001723737.1 789093 R 481805 CDS YP_001723738.1 170018784 6065032 791296..791553 1 NC_010468.1 KEGG: eca:ECA2935 hypothetical protein; hypothetical protein 791553 6065032 EcolC_0738 Escherichia coli ATCC 8739 hypothetical protein YP_001723738.1 791296 D 481805 CDS YP_001723739.1 170018785 6065763 complement(792111..792878) 1 NC_010468.1 Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit 792878 fecE 6065763 fecE Escherichia coli ATCC 8739 iron-dicitrate transporter ATP-binding subunit YP_001723739.1 792111 R 481805 CDS YP_001723740.1 170018786 6065119 complement(792879..793835) 1 NC_010468.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD 793835 fecD 6065119 fecD Escherichia coli ATCC 8739 iron-dicitrate transporter subunit FecD YP_001723740.1 792879 R 481805 CDS YP_001723741.1 170018787 6065114 complement(793832..794830) 1 NC_010468.1 part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease 794830 fecC 6065114 fecC Escherichia coli ATCC 8739 iron-dicitrate transporter permease YP_001723741.1 793832 R 481805 CDS YP_001723742.1 170018788 6065947 complement(794827..795729) 1 NC_010468.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit 795729 fecB 6065947 fecB Escherichia coli ATCC 8739 iron-dicitrate transporter substrate-binding subunit YP_001723742.1 794827 R 481805 CDS YP_001723743.1 170018789 6064739 complement(795774..798098) 1 NC_010468.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB short domain; TonB-dependent receptor plug; KEGG: sdy:SDY_4297 citrate-dependent iron transport, outer membrane receptor; TonB-dependent siderophore receptor 798098 6064739 EcolC_0743 Escherichia coli ATCC 8739 TonB-dependent siderophore receptor YP_001723743.1 795774 R 481805 CDS YP_001723744.1 170018790 6066577 complement(798185..799138) 1 NC_010468.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR 799138 6066577 EcolC_0744 Escherichia coli ATCC 8739 fec operon regulator FecR YP_001723744.1 798185 R 481805 CDS YP_001723745.1 170018791 6066802 complement(799135..799656) 1 NC_010468.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI 799656 6066802 EcolC_0745 Escherichia coli ATCC 8739 RNA polymerase sigma factor FecI YP_001723745.1 799135 R 481805 CDS YP_001723746.1 170018792 6067103 complement(800831..802093) 1 NC_010468.1 PFAM: integrase family protein; KEGG: sfx:S4822 putative P4-type integrase; integrase family protein 802093 6067103 EcolC_0747 Escherichia coli ATCC 8739 integrase family protein YP_001723746.1 800831 R 481805 CDS YP_001723747.1 170018793 6067162 complement(802472..803179) 1 NC_010468.1 PFAM: protein of unknown function DUF554; KEGG: ssn:SSON_3229 putative transport protein; hypothetical protein 803179 6067162 EcolC_0748 Escherichia coli ATCC 8739 hypothetical protein YP_001723747.1 802472 R 481805 CDS YP_001723748.1 170018794 6065463 803577..805712 1 NC_010468.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sfx:S3165 ornithine decarboxylase isozyme; ornithine decarboxylase 805712 6065463 EcolC_0749 Escherichia coli ATCC 8739 ornithine decarboxylase YP_001723748.1 803577 D 481805 CDS YP_001723749.1 170018795 6066852 complement(805762..807018) 1 NC_010468.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: sbo:SBO_3026 NupG; nucleoside transporter 807018 6066852 EcolC_0750 Escherichia coli ATCC 8739 nucleoside transporter YP_001723749.1 805762 R 481805 CDS YP_001723750.1 170018796 6066511 complement(807220..808302) 1 NC_010468.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 808302 mltC 6066511 mltC Escherichia coli ATCC 8739 murein transglycosylase C YP_001723750.1 807220 R 481805 CDS YP_001723751.1 170018797 6064938 complement(808364..808639) 1 NC_010468.1 PFAM: Fe(II) trafficking protein YggX; KEGG: sdy:SDY_3110 hypothetical protein; hypothetical protein 808639 6064938 EcolC_0752 Escherichia coli ATCC 8739 hypothetical protein YP_001723751.1 808364 R 481805 CDS YP_001723752.1 170018798 6064935 complement(808667..809719) 1 NC_010468.1 KEGG: sbo:SBO_3029 adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; adenine DNA glycosylase 809719 6064935 EcolC_0753 Escherichia coli ATCC 8739 adenine DNA glycosylase YP_001723752.1 808667 R 481805 CDS YP_001723753.1 170018799 6067160 809880..810599 1 NC_010468.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 810599 trmB 6067160 trmB Escherichia coli ATCC 8739 tRNA (guanine-N(7)-)-methyltransferase YP_001723753.1 809880 D 481805 CDS YP_001723754.1 170018800 6067158 810599..810925 1 NC_010468.1 PFAM: protein of unknown function DUF469; KEGG: sdy:SDY_3113 hypothetical protein; hypothetical protein 810925 6067158 EcolC_0755 Escherichia coli ATCC 8739 hypothetical protein YP_001723754.1 810599 D 481805 CDS YP_001723755.1 170018801 6067155 811109..811828 1 NC_010468.1 KEGG: sdy:SDY_3114 hypothetical protein; hypothetical protein 811828 6067155 EcolC_0756 Escherichia coli ATCC 8739 hypothetical protein YP_001723755.1 811109 D 481805 CDS YP_001723756.1 170018802 6066402 812004..813050 1 NC_010468.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 813050 ansB 6066402 ansB Escherichia coli ATCC 8739 L-asparaginase II YP_001723756.1 812004 D 481805 CDS YP_001723757.1 170018803 6065893 813167..814174 1 NC_010468.1 PFAM: protein of unknown function DUF1202; KEGG: sbo:SBO_3034 putative alpha helix chain; hypothetical protein 814174 6065893 EcolC_0758 Escherichia coli ATCC 8739 hypothetical protein YP_001723757.1 813167 D 481805 CDS YP_001723758.1 170018804 6066690 complement(814329..815465) 1 NC_010468.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 815465 6066690 EcolC_0759 Escherichia coli ATCC 8739 coproporphyrinogen III oxidase YP_001723758.1 814329 R 481805 CDS YP_001723759.1 170018805 6066447 complement(815458..816051) 1 NC_010468.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 816051 6066447 EcolC_0760 Escherichia coli ATCC 8739 putative deoxyribonucleotide triphosphate pyrophosphatase YP_001723759.1 815458 R 481805 CDS YP_001723760.1 170018806 6065585 complement(816059..816349) 1 NC_010468.1 PFAM: protein of unknown function DUF167; KEGG: sfv:SFV_3007 hypothetical protein; hypothetical protein 816349 6065585 EcolC_0761 Escherichia coli ATCC 8739 hypothetical protein YP_001723760.1 816059 R 481805 CDS YP_001723761.1 170018807 6064825 complement(816346..816912) 1 NC_010468.1 PFAM: protein of unknown function YGGT; KEGG: sdy:SDY_3120 putative resistance protein; hypothetical protein 816912 6064825 EcolC_0762 Escherichia coli ATCC 8739 hypothetical protein YP_001723761.1 816346 R 481805 CDS YP_001723762.1 170018808 6065332 complement(816930..817634) 1 NC_010468.1 PFAM: alanine racemase domain protein; KEGG: sdy:SDY_3122 hypothetical protein; alanine racemase domain-containing protein 817634 6065332 EcolC_0763 Escherichia coli ATCC 8739 alanine racemase domain-containing protein YP_001723762.1 816930 R 481805 CDS YP_001723763.1 170018809 6065216 817652..818632 1 NC_010468.1 KEGG: sfv:SFV_3004 putative protein transport; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; twitching motility protein 818632 6065216 EcolC_0764 Escherichia coli ATCC 8739 twitching motility protein YP_001723763.1 817652 D 481805 CDS YP_001723764.1 170018810 6065711 complement(818816..819232) 1 NC_010468.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 819232 6065711 EcolC_0765 Escherichia coli ATCC 8739 Holliday junction resolvase-like protein YP_001723764.1 818816 R 481805 CDS YP_001723765.1 170018811 6064923 complement(819232..819867) 1 NC_010468.1 PFAM: protein of unknown function DUF179; KEGG: sdy:SDY_3124 hypothetical protein; hypothetical protein 819867 6064923 EcolC_0766 Escherichia coli ATCC 8739 hypothetical protein YP_001723765.1 819232 R 481805 CDS YP_001723766.1 170018812 6064899 complement(819904..820854) 1 NC_010468.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 820854 6064899 EcolC_0767 Escherichia coli ATCC 8739 glutathione synthetase YP_001723766.1 819904 R 481805 CDS YP_001723767.1 170018813 6064919 complement(820867..821598) 1 NC_010468.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 821598 6064919 EcolC_0768 Escherichia coli ATCC 8739 16S ribosomal RNA methyltransferase RsmE YP_001723767.1 820867 R 481805 CDS YP_001723768.1 170018814 6065547 complement(821678..822385) 1 NC_010468.1 PFAM: Endonuclease I; KEGG: sbo:SBO_3045 DNA-specific endonuclease I; deoxyribonuclease I 822385 6065547 EcolC_0769 Escherichia coli ATCC 8739 deoxyribonuclease I YP_001723768.1 821678 R 481805 CDS YP_001723769.1 170018815 6065544 complement(822480..822935) 1 NC_010468.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: sbo:SBO_3046 hypothetical protein; hypothetical protein 822935 6065544 EcolC_0770 Escherichia coli ATCC 8739 hypothetical protein YP_001723769.1 822480 R 481805 CDS YP_001723770.1 170018816 6066714 complement(823054..824448) 1 NC_010468.1 KEGG: sdy:SDY_3129 galactose-proton symport of transport system; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; sugar transporter 824448 6066714 EcolC_0771 Escherichia coli ATCC 8739 sugar transporter YP_001723770.1 823054 R 481805 CDS YP_001723771.1 170018817 6066565 complement(824884..826038) 1 NC_010468.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 826038 6066565 EcolC_0772 Escherichia coli ATCC 8739 S-adenosylmethionine synthetase YP_001723771.1 824884 R 481805 CDS YP_001723772.1 170018818 6065520 826833..828809 1 NC_010468.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 828809 6065520 EcolC_0773 Escherichia coli ATCC 8739 arginine decarboxylase YP_001723772.1 826833 D 481805 CDS YP_001723773.1 170018819 6066730 828947..829867 1 NC_010468.1 catalyzes the formation of putrescine from agmatine; agmatinase 829867 6066730 EcolC_0774 Escherichia coli ATCC 8739 agmatinase YP_001723773.1 828947 D 481805 CDS YP_001723774.1 170018820 6066006 complement(830073..830831) 1 NC_010468.1 PFAM: peptidase M48 Ste24p; KEGG: sbo:SBO_3053 hypothetical protein; peptidase M48 Ste24p 830831 6066006 EcolC_0775 Escherichia coli ATCC 8739 peptidase M48 Ste24p YP_001723774.1 830073 R 481805 CDS YP_001723775.1 170018821 6066655 831109..833100 1 NC_010468.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 833100 6066655 EcolC_0776 Escherichia coli ATCC 8739 transketolase YP_001723775.1 831109 D 481805 CDS YP_001723776.1 170018822 6065402 833414..833857 1 NC_010468.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; putative mannitol phosphotransferase subunit EIIA 833857 cmtB 6065402 cmtB Escherichia coli ATCC 8739 putative mannitol phosphotransferase subunit EIIA YP_001723776.1 833414 D 481805 CDS YP_001723777.1 170018823 6066569 833885..835273 1 NC_010468.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: sdy:SDY_3144 PTS system, mannitol-specific enzyme II component, cryptic; PTS system mannitol-specific transporter subunit IIC 835273 6066569 EcolC_0778 Escherichia coli ATCC 8739 PTS system mannitol-specific transporter subunit IIC YP_001723777.1 833885 D 481805 CDS YP_001723778.1 170018824 6065758 835288..836565 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfv:SFV_2983 putative oxidoreductase; alcohol dehydrogenase 836565 6065758 EcolC_0779 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001723778.1 835288 D 481805 CDS YP_001723779.1 170018825 6064608 836562..837527 1 NC_010468.1 TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sfv:SFV_2982 hypothetical protein; fructose-1,6-bisphosphatase II-like protein 837527 6064608 EcolC_0780 Escherichia coli ATCC 8739 fructose-1,6-bisphosphatase II-like protein YP_001723779.1 836562 D 481805 CDS YP_001723780.1 170018826 6066651 837549..838058 1 NC_010468.1 PFAM: Mannitol repressor; KEGG: sdy:SDY_3147 putative transcriptional regulator; putative DNA-binding transcriptional regulator 838058 6066651 EcolC_0781 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001723780.1 837549 D 481805 CDS YP_001723781.1 170018827 6065053 838055..838768 1 NC_010468.1 KEGG: sbo:SBO_3060 putative kinase; putative fructose transport system kinase 838768 frcK 6065053 frcK Escherichia coli ATCC 8739 putative fructose transport system kinase YP_001723781.1 838055 D 481805 CDS YP_001723782.1 170018828 6066654 839053..840072 1 NC_010468.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 840072 6066654 EcolC_0783 Escherichia coli ATCC 8739 erythrose 4-phosphate dehydrogenase YP_001723782.1 839053 D 481805 CDS YP_001723783.1 170018829 6067318 840122..841285 1 NC_010468.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 841285 pgk 6067318 pgk Escherichia coli ATCC 8739 phosphoglycerate kinase YP_001723783.1 840122 D 481805 CDS YP_001723784.1 170018830 6065450 841500..842579 1 NC_010468.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 842579 6065450 EcolC_0785 Escherichia coli ATCC 8739 fructose-bisphosphate aldolase YP_001723784.1 841500 D 481805 CDS YP_001723785.1 170018831 6065892 842937..843797 1 NC_010468.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 843797 6065892 EcolC_0786 Escherichia coli ATCC 8739 mechanosensitive channel MscS YP_001723785.1 842937 D 481805 CDS YP_001723786.1 170018832 6067460 843936..844571 1 NC_010468.1 Involved in the export of arginine; arginine exporter protein 844571 6067460 EcolC_0787 Escherichia coli ATCC 8739 arginine exporter protein YP_001723786.1 843936 D 481805 CDS YP_001723787.1 170018833 6066088 844664..845404 1 NC_010468.1 PFAM: protein of unknown function DUF541; KEGG: sdy:SDY_3160 putative actin; hypothetical protein 845404 6066088 EcolC_0788 Escherichia coli ATCC 8739 hypothetical protein YP_001723787.1 844664 D 481805 CDS YP_001723788.1 170018834 6065839 845571..846467 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3073 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 846467 6065839 EcolC_0789 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001723788.1 845571 D 481805 CDS YP_001723789.1 170018835 6065725 complement(846464..847942) 1 NC_010468.1 KEGG: ssn:SSON_3071 putative coenzyme A transferase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase; succinate CoA transferase 847942 6065725 EcolC_0790 Escherichia coli ATCC 8739 succinate CoA transferase YP_001723789.1 846464 R 481805 CDS YP_001723790.1 170018836 6065086 complement(847966..848751) 1 NC_010468.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 848751 6065086 EcolC_0791 Escherichia coli ATCC 8739 methylmalonyl-CoA decarboxylase YP_001723790.1 847966 R 481805 CDS YP_001723791.1 170018837 6066499 complement(848762..849757) 1 NC_010468.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 849757 6066499 EcolC_0792 Escherichia coli ATCC 8739 arginine/ornithine transport system ATPase YP_001723791.1 848762 R 481805 CDS YP_001723792.1 170018838 6064709 complement(849750..851894) 1 NC_010468.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 851894 6064709 EcolC_0793 Escherichia coli ATCC 8739 methylmalonyl-CoA mutase YP_001723792.1 849750 R 481805 CDS YP_001723793.1 170018839 6065256 complement(852098..852991) 1 NC_010468.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 852991 6065256 EcolC_0794 Escherichia coli ATCC 8739 chromosome replication initiation inhibitor protein YP_001723793.1 852098 R 481805 CDS YP_001723794.1 170018840 6066586 853133..853363 1 NC_010468.1 hypothetical protein 853363 6066586 EcolC_0795 Escherichia coli ATCC 8739 hypothetical protein YP_001723794.1 853133 D 481805 CDS YP_001723795.1 170018841 6066156 853419..854078 1 NC_010468.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 854078 6066156 EcolC_0796 Escherichia coli ATCC 8739 ribose-5-phosphate isomerase A YP_001723795.1 853419 D 481805 CDS YP_001723796.1 170018842 6066820 854334..855566 1 NC_010468.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 855566 6066820 EcolC_0797 Escherichia coli ATCC 8739 D-3-phosphoglycerate dehydrogenase YP_001723796.1 854334 D 481805 CDS YP_001723797.1 170018843 6065342 complement(855955..856557) 1 NC_010468.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 856557 6065342 EcolC_0798 Escherichia coli ATCC 8739 putative ligase YP_001723797.1 855955 R 481805 CDS YP_001723798.1 170018844 6065404 complement(856803..857132) 1 NC_010468.1 PFAM: protein of unknown function DUF710; KEGG: sbo:SBO_3082 hypothetical protein; Z-ring-associated protein 857132 6065404 EcolC_0799 Escherichia coli ATCC 8739 Z-ring-associated protein YP_001723798.1 856803 R 481805 CDS YP_001723799.2 229597232 6066670 857300..857878 1 NC_010468.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 857878 6066670 EcolC_0800 Escherichia coli ATCC 8739 hypothetical protein YP_001723799.2 857300 D 481805 CDS YP_001723800.1 170018846 6066555 857904..859229 1 NC_010468.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 859229 6066555 EcolC_0801 Escherichia coli ATCC 8739 proline aminopeptidase P II YP_001723800.1 857904 D 481805 CDS YP_001723801.1 170018847 6065322 859226..860404 1 NC_010468.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 860404 6065322 EcolC_0802 Escherichia coli ATCC 8739 2-octaprenyl-6-methoxyphenyl hydroxylase YP_001723801.1 859226 D 481805 CDS YP_001723802.1 170018848 6065780 860427..861629 1 NC_010468.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: ssn:SSON_3059 hypothetical protein; hypothetical protein 861629 6065780 EcolC_0803 Escherichia coli ATCC 8739 hypothetical protein YP_001723802.1 860427 D 481805 CDS YP_001723803.1 170018849 6065305 862077..863171 1 NC_010468.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 863171 gcvT 6065305 gcvT Escherichia coli ATCC 8739 glycine cleavage system aminomethyltransferase T YP_001723803.1 862077 D 481805 CDS YP_001723804.1 170018850 6066682 863195..863584 1 NC_010468.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 863584 6066682 EcolC_0805 Escherichia coli ATCC 8739 glycine cleavage system protein H YP_001723804.1 863195 D 481805 CDS YP_001723805.1 170018851 6064873 863703..866576 1 NC_010468.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 866576 6064873 EcolC_0806 Escherichia coli ATCC 8739 glycine dehydrogenase YP_001723805.1 863703 D 481805 CDS YP_001723806.1 170018852 6065924 866843..867586 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sfx:S3087 putative oxidoreductase; hypothetical protein 867586 6065924 EcolC_0807 Escherichia coli ATCC 8739 hypothetical protein YP_001723806.1 866843 D 481805 CDS YP_001723807.1 170018853 6065927 complement(867643..869076) 1 NC_010468.1 PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_3054 6-phospho-beta-glucosidase A, cryptic; glycoside hydrolase family protein 869076 6065927 EcolC_0808 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001723807.1 867643 R 481805 CDS YP_001723808.1 170018854 6064660 869121..869432 1 NC_010468.1 PFAM: protein of unknown function DUF437; KEGG: sdy:SDY_3181 hypothetical protein; hypothetical protein 869432 6064660 EcolC_0809 Escherichia coli ATCC 8739 hypothetical protein YP_001723808.1 869121 D 481805 CDS YP_001723809.1 170018855 6066548 869596..870255 1 NC_010468.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: ssn:SSON_3052 putative oxidoreductase; hemolysin III family channel protein 870255 6066548 EcolC_0810 Escherichia coli ATCC 8739 hemolysin III family channel protein YP_001723809.1 869596 D 481805 CDS YP_001723810.1 170018856 6066545 complement(870451..871431) 1 NC_010468.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 871431 6066545 EcolC_0811 Escherichia coli ATCC 8739 putative global regulator YP_001723810.1 870451 R 481805 CDS YP_001723811.1 170018857 6065645 871674..871940 1 NC_010468.1 PFAM: protein of unknown function DUF339; KEGG: sdy:SDY_3185 hypothetical protein; hypothetical protein 871940 6065645 EcolC_0812 Escherichia coli ATCC 8739 hypothetical protein YP_001723811.1 871674 D 481805 CDS YP_001723812.1 170018858 6064732 871921..872328 1 NC_010468.1 PFAM: protein of unknown function DUF1434; KEGG: sbo:SBO_3096 hypothetical protein; hypothetical protein 872328 6064732 EcolC_0813 Escherichia coli ATCC 8739 hypothetical protein YP_001723812.1 871921 D 481805 CDS YP_001723813.1 170018859 6065811 complement(872368..872889) 1 NC_010468.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 872889 6065811 EcolC_0814 Escherichia coli ATCC 8739 flavodoxin FldB YP_001723813.1 872368 R 481805 CDS YP_001723814.1 170018860 6066903 873001..873897 1 NC_010468.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 873897 xerD 6066903 xerD Escherichia coli ATCC 8739 site-specific tyrosine recombinase XerD YP_001723814.1 873001 D 481805 CDS YP_001723815.1 170018861 6065861 873922..874632 1 NC_010468.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 874632 6065861 EcolC_0816 Escherichia coli ATCC 8739 thiol:disulfide interchange protein DsbC YP_001723815.1 873922 D 481805 CDS YP_001723816.1 170018862 6066416 874638..876371 1 NC_010468.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 876371 6066416 EcolC_0817 Escherichia coli ATCC 8739 ssDNA exonuclease RecJ YP_001723816.1 874638 D 481805 CDS YP_001723817.1 170018863 6065042 join(876462..876536,876538..877560) 1 NC_010468.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 877560 prfB 6065042 prfB Escherichia coli ATCC 8739 peptide chain release factor 2 YP_001723817.1 876462 D 481805 CDS YP_001723818.1 170018864 6066114 877570..879087 1 NC_010468.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 879087 lysS 6066114 lysS Escherichia coli ATCC 8739 lysyl-tRNA synthetase YP_001723818.1 877570 D 481805 CDS YP_001723819.1 170018865 6064889 complement(879130..879678) 1 NC_010468.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 879678 6064889 EcolC_0820 Escherichia coli ATCC 8739 isopentenyl-diphosphate delta-isomerase YP_001723819.1 879130 R 481805 CDS YP_001723820.1 170018866 6066763 complement(879928..881376) 1 NC_010468.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3041 putative permease; xanthine permease 881376 6066763 EcolC_0821 Escherichia coli ATCC 8739 xanthine permease YP_001723820.1 879928 R 481805 CDS YP_001723821.1 170018867 6065417 881812..883731 1 NC_010468.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 883731 6065417 EcolC_0822 Escherichia coli ATCC 8739 putative oxidoreductase Fe-S binding subunit YP_001723821.1 881812 D 481805 CDS YP_001723822.1 170018868 6064729 883731..884219 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_3038 putative oxidoreductase, Fe-S subunit; 4Fe-4S ferredoxin 884219 6064729 EcolC_0823 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001723822.1 883731 D 481805 CDS YP_001723823.1 170018869 6066760 complement(884255..885622) 1 NC_010468.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: spe:Spro_4431 xanthine/uracil/vitamin C permease; xanthine/uracil/vitamin C permease 885622 6066760 EcolC_0824 Escherichia coli ATCC 8739 xanthine/uracil/vitamin C permease YP_001723823.1 884255 R 481805 CDS YP_001723824.1 170018870 6067212 complement(885658..886974) 1 NC_010468.1 Catalyzes the deamination of guanine; guanine deaminase 886974 6067212 EcolC_0825 Escherichia coli ATCC 8739 guanine deaminase YP_001723824.1 885658 R 481805 CDS YP_001723825.1 170018871 6065500 complement(886992..888392) 1 NC_010468.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: aha:AHA_2174 xanthine/uracil permease family protein; uracil-xanthine permease 888392 6065500 EcolC_0826 Escherichia coli ATCC 8739 uracil-xanthine permease YP_001723825.1 886992 R 481805 CDS YP_001723826.1 170018872 6065961 complement(888557..891427) 1 NC_010468.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 891427 6065961 EcolC_0827 Escherichia coli ATCC 8739 putative selenate reductase subunit YgfN YP_001723826.1 888557 R 481805 CDS YP_001723827.1 170018873 6065301 complement(891424..892203) 1 NC_010468.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 892203 6065301 EcolC_0828 Escherichia coli ATCC 8739 putative selenate reductase subunit YgfM YP_001723827.1 891424 R 481805 CDS YP_001723828.1 170018874 6065278 complement(892254..893582) 1 NC_010468.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 893582 6065278 EcolC_0829 Escherichia coli ATCC 8739 putative chlorohydrolase/aminohydrolase YP_001723828.1 892254 R 481805 CDS YP_001723829.1 170018875 6065389 complement(893585..896683) 1 NC_010468.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 896683 6065389 EcolC_0830 Escherichia coli ATCC 8739 putative selenate reductase subunit YgfK YP_001723829.1 893585 R 481805 CDS YP_001723830.1 170018876 6066696 complement(897005..897520) 1 NC_010468.1 KEGG: ssn:SSON_3028 hypothetical protein; hypothetical protein 897520 6066696 EcolC_0831 Escherichia coli ATCC 8739 hypothetical protein YP_001723830.1 897005 R 481805 CDS YP_001723831.1 170018877 6064450 897686..898456 1 NC_010468.1 KEGG: ssn:SSON_3027 hypothetical protein; hypothetical protein 898456 6064450 EcolC_0832 Escherichia coli ATCC 8739 hypothetical protein YP_001723831.1 897686 D 481805 CDS YP_001723832.1 170018878 6067086 898504..900129 1 NC_010468.1 TIGRFAM: selenium-dependent molybdenum hydroxylase system protein, YqeB family; PFAM: biotin/lipoyl attachment domain-containing protein; protein of unknown function DUF182; KEGG: sbo:SBO_3109 putative synthase; selenium-dependent molybdenum hydroxylase system protein 900129 6067086 EcolC_0833 Escherichia coli ATCC 8739 selenium-dependent molybdenum hydroxylase system protein YP_001723832.1 898504 D 481805 CDS YP_001723833.1 170018879 6065851 complement(900350..901282) 1 NC_010468.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 901282 6065851 EcolC_0834 Escherichia coli ATCC 8739 carbamate kinase YP_001723833.1 900350 R 481805 CDS YP_001723834.1 170018880 6065012 complement(901330..902715) 1 NC_010468.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 902715 6065012 EcolC_0835 Escherichia coli ATCC 8739 phenylhydantoinase YP_001723834.1 901330 R 481805 CDS YP_001723835.1 170018881 6066008 complement(902768..903979) 1 NC_010468.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 903979 6066008 EcolC_0836 Escherichia coli ATCC 8739 peptidase YP_001723835.1 902768 R 481805 CDS YP_001723836.1 170018882 6065236 complement(904037..905233) 1 NC_010468.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 905233 6065236 EcolC_0837 Escherichia coli ATCC 8739 diaminopropionate ammonia-lyase YP_001723836.1 904037 R 481805 CDS YP_001723837.1 170018883 6066675 complement(905291..906481) 1 NC_010468.1 TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: ssn:SSON_3021 putative carbamoyl transferase; aspartate/ornithine carbamoyltransferase family protein 906481 6066675 EcolC_0838 Escherichia coli ATCC 8739 aspartate/ornithine carbamoyltransferase family protein YP_001723837.1 905291 R 481805 CDS YP_001723838.1 170018884 6067240 906957..908735 1 NC_010468.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: PAS domain containing protein; AAA ATPase; KEGG: ssn:SSON_3020 putative transcriptional regulator; PAS modulated sigma54 specific transcriptional regulator 908735 6067240 EcolC_0839 Escherichia coli ATCC 8739 PAS modulated sigma54 specific transcriptional regulator YP_001723838.1 906957 D 481805 CDS YP_001723839.1 170018885 6065539 complement(908775..909254) 1 NC_010468.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 909254 6065539 EcolC_0840 Escherichia coli ATCC 8739 xanthine dehydrogenase subunit XdhC YP_001723839.1 908775 R 481805 CDS YP_001723840.1 170018886 6066027 complement(909251..910129) 1 NC_010468.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 910129 6066027 EcolC_0841 Escherichia coli ATCC 8739 xanthine dehydrogenase subunit XdhB YP_001723840.1 909251 R 481805 CDS YP_001723841.1 170018887 6064964 complement(910140..912437) 1 NC_010468.1 putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 912437 6064964 EcolC_0842 Escherichia coli ATCC 8739 xanthine dehydrogenase subunit XdhA YP_001723841.1 910140 R 481805 CDS YP_001723842.1 170018888 6066656 912852..913607 1 NC_010468.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: ssn:SSON_3016 putative lipoprotein; peptidase M23B 913607 6066656 EcolC_0843 Escherichia coli ATCC 8739 peptidase M23B YP_001723842.1 912852 D 481805 CDS YP_001723843.1 170018889 6066891 913985..915607 1 NC_010468.1 KEGG: ssn:SSON_3014 hypothetical protein; hypothetical protein 915607 6066891 EcolC_0844 Escherichia coli ATCC 8739 hypothetical protein YP_001723843.1 913985 D 481805 CDS YP_001723844.1 170018890 6066263 915739..916686 1 NC_010468.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; surface presentation of antigens protein SpaO 916686 6066263 EcolC_0845 Escherichia coli ATCC 8739 surface presentation of antigens protein SpaO YP_001723844.1 915739 D 481805 CDS YP_001723845.1 170018891 6066702 916676..917341 1 NC_010468.1 part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP 917341 spaP 6066702 spaP Escherichia coli ATCC 8739 surface presentation of antigens protein SpaP YP_001723845.1 916676 D 481805 CDS YP_001723846.1 170018892 6067332 917351..917611 1 NC_010468.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ family 3; KEGG: cvi:CV_2623 surface presentation of antigens; secretory proteins; HrpO family type III secretion protein 917611 6067332 EcolC_0847 Escherichia coli ATCC 8739 HrpO family type III secretion protein YP_001723846.1 917351 D 481805 CDS YP_001723847.1 170018893 6067644 917613..918380 1 NC_010468.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: cvi:CV_2622 surface presentation of antigens; secretory proteins; type III secretion protein SpaR/YscT/HrcT 918380 6067644 EcolC_0848 Escherichia coli ATCC 8739 type III secretion protein SpaR/YscT/HrcT YP_001723847.1 917613 D 481805 CDS YP_001723848.1 170018894 6065283 complement(919865..920365) 1 NC_010468.1 PFAM: regulatory protein LuxR; LuxR family transcriptional regulator 920365 6065283 EcolC_0850 Escherichia coli ATCC 8739 LuxR family transcriptional regulator YP_001723848.1 919865 R 481805 CDS YP_001723849.1 170018895 6064965 920622..921803 1 NC_010468.1 TIGRFAM: type III secretion system protein PrgH/EprH; PFAM: Type III secretion system PrgH/EprHfmaily protein; KEGG: stt:t2776 pathogenicity 1 island effector protein; type III secretion system protein PrgH/EprH 921803 6064965 EcolC_0851 Escherichia coli ATCC 8739 type III secretion system protein PrgH/EprH YP_001723849.1 920622 D 481805 CDS YP_001723850.1 170018896 6067002 921841..922056 1 NC_010468.1 TIGRFAM: type III secretion system needle protein; KEGG: cvi:CV_2422 cell invasion protein - cytoplasmic; type III secretion system needle protein 922056 6067002 EcolC_0852 Escherichia coli ATCC 8739 type III secretion system needle protein YP_001723850.1 921841 D 481805 CDS YP_001723851.1 170018897 6064409 922076..922408 1 NC_010468.1 KEGG: cvi:CV_2421 cell invasion protein - cytoplasmic; hypothetical protein 922408 6064409 EcolC_0853 Escherichia coli ATCC 8739 hypothetical protein YP_001723851.1 922076 D 481805 CDS YP_001723852.1 170018898 6064366 complement(join(922824..923267,923267..923521)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 923521 6064366 EcolC_0855 Escherichia coli ATCC 8739 insertion element protein YP_001723852.1 922824 R 481805 CDS YP_001723853.1 170018899 6065171 924530..924724 1 NC_010468.1 hypothetical protein 924724 6065171 EcolC_0857 Escherichia coli ATCC 8739 hypothetical protein YP_001723853.1 924530 D 481805 CDS YP_001723854.1 170018900 6065137 924727..925158 1 NC_010468.1 hypothetical protein 925158 6065137 EcolC_0858 Escherichia coli ATCC 8739 hypothetical protein YP_001723854.1 924727 D 481805 CDS YP_001723855.1 170018901 6065122 925377..926009 1 NC_010468.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: sgl:SG1279 putative two-component response regulator; two component LuxR family transcriptional regulator 926009 6065122 EcolC_0859 Escherichia coli ATCC 8739 two component LuxR family transcriptional regulator YP_001723855.1 925377 D 481805 CDS YP_001723856.1 170018902 6065081 complement(926054..926428) 1 NC_010468.1 PFAM: Lytic transglycosylase catalytic; KEGG: stt:t4248 hypothetical protein; lytic transglycosylase 926428 6065081 EcolC_0860 Escherichia coli ATCC 8739 lytic transglycosylase YP_001723856.1 926054 R 481805 CDS YP_001723857.1 170018903 6065070 complement(926612..926830) 1 NC_010468.1 hypothetical protein 926830 6065070 EcolC_0861 Escherichia coli ATCC 8739 hypothetical protein YP_001723857.1 926612 R 481805 CDS YP_001723858.1 170018904 6065016 complement(926998..928374) 1 NC_010468.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: cvi:CV_2640 invasion genes transcription activator; transcriptional regulator 928374 6065016 EcolC_0862 Escherichia coli ATCC 8739 transcriptional regulator YP_001723858.1 926998 R 481805 CDS YP_001723859.1 170018905 6065002 complement(928709..929200) 1 NC_010468.1 PFAM: Tetratricopeptide TPR_3; KEGG: ssn:SSON_3011 hypothetical protein; hypothetical protein 929200 6065002 EcolC_0863 Escherichia coli ATCC 8739 hypothetical protein YP_001723859.1 928709 R 481805 CDS YP_001723860.1 170018906 6064992 complement(929467..929913) 1 NC_010468.1 KEGG: ssn:SSON_3010 hypothetical protein; hypothetical protein 929913 6064992 EcolC_0864 Escherichia coli ATCC 8739 hypothetical protein YP_001723860.1 929467 R 481805 CDS YP_001723861.1 170018907 6064979 929967..930203 1 NC_010468.1 hypothetical protein 930203 6064979 EcolC_0865 Escherichia coli ATCC 8739 hypothetical protein YP_001723861.1 929967 D 481805 CDS YP_001723862.1 170018908 6064972 930343..930768 1 NC_010468.1 hypothetical protein 930768 6064972 EcolC_0866 Escherichia coli ATCC 8739 hypothetical protein YP_001723862.1 930343 D 481805 CDS YP_001723863.1 170018909 6064967 complement(930917..931399) 1 NC_010468.1 KEGG: ssn:SSON_3009 hypothetical protein; hypothetical protein 931399 6064967 EcolC_0867 Escherichia coli ATCC 8739 hypothetical protein YP_001723863.1 930917 R 481805 CDS YP_001723864.1 170018910 6064942 complement(931392..932201) 1 NC_010468.1 PFAM: transcriptional regulator domain protein; KEGG: kpn:KPN_00272 putative sensory transducer; transcriptional regulator CadC 932201 6064942 EcolC_0868 Escherichia coli ATCC 8739 transcriptional regulator CadC YP_001723864.1 931392 R 481805 CDS YP_001723865.1 170018911 6064902 complement(932535..933167) 1 NC_010468.1 KEGG: ssn:SSON_3006 hypothetical protein; hypothetical protein 933167 6064902 EcolC_0869 Escherichia coli ATCC 8739 hypothetical protein YP_001723865.1 932535 R 481805 CDS YP_001723866.1 170018912 6064882 complement(933627..934856) 1 NC_010468.1 TIGRFAM: serine transporter; PFAM: Amino acid transporter transmembrane; KEGG: ssn:SSON_3005 putative transporter protein; serine transporter 934856 6064882 EcolC_0870 Escherichia coli ATCC 8739 serine transporter YP_001723866.1 933627 R 481805 CDS YP_001723867.1 170018913 6064856 935111..936292 1 NC_010468.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 936292 6064856 EcolC_0871 Escherichia coli ATCC 8739 acetyl-CoA acetyltransferase YP_001723867.1 935111 D 481805 CDS YP_001723868.1 170018914 6064854 936579..937415 1 NC_010468.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 937415 6064854 EcolC_0872 Escherichia coli ATCC 8739 5-keto-4-deoxyuronate isomerase YP_001723868.1 936579 D 481805 CDS YP_001723869.1 170018915 6064842 937445..938206 1 NC_010468.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 938206 6064842 EcolC_0873 Escherichia coli ATCC 8739 2-deoxy-D-gluconate 3-dehydrogenase YP_001723869.1 937445 D 481805 CDS YP_001723870.1 170018916 6064833 938521..939939 1 NC_010468.1 KEGG: ssn:SSON_3001 low-affinity L-arabinose transport system proton symport protein; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; sugar transporter 939939 6064833 EcolC_0874 Escherichia coli ATCC 8739 sugar transporter YP_001723870.1 938521 D 481805 CDS YP_001723871.1 170018917 6064817 940068..940760 1 NC_010468.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: sfv:SFV_2918 putative resistance proteins; putative racemase 940760 6064817 EcolC_0875 Escherichia coli ATCC 8739 putative racemase YP_001723871.1 940068 D 481805 CDS YP_001723872.1 170018918 6064811 complement(940747..941682) 1 NC_010468.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 941682 6064811 EcolC_0876 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator LysR YP_001723872.1 940747 R 481805 CDS YP_001723873.1 170018919 6064787 941804..943066 1 NC_010468.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 943066 6064787 EcolC_0877 Escherichia coli ATCC 8739 diaminopimelate decarboxylase YP_001723873.1 941804 D 481805 CDS YP_001723874.1 170018920 6064784 complement(943073..944104) 1 NC_010468.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 944104 6064784 EcolC_0878 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator GalR YP_001723874.1 943073 R 481805 CDS YP_001723875.1 170018921 6064777 944690..946849 1 NC_010468.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 946849 6064777 EcolC_0879 Escherichia coli ATCC 8739 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_001723875.1 944690 D 481805 CDS YP_001723876.1 170018922 6064774 946842..948035 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2727 putative resistance proteins; lysophospholipid transporter LplT 948035 6064774 EcolC_0880 Escherichia coli ATCC 8739 lysophospholipid transporter LplT YP_001723876.1 946842 D 481805 CDS YP_001723877.1 170018923 6064747 complement(948067..949107) 1 NC_010468.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 949107 tas 6064747 tas Escherichia coli ATCC 8739 putative aldo-keto reductase YP_001723877.1 948067 R 481805 CDS YP_001723878.1 170018924 6064734 complement(949215..949433) 1 NC_010468.1 PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3050 hypothetical protein; hypothetical protein 949433 6064734 EcolC_0882 Escherichia coli ATCC 8739 hypothetical protein YP_001723878.1 949215 R 481805 CDS YP_001723879.1 170018925 6064724 complement(949571..950284) 1 NC_010468.1 PFAM: Integral membrane protein TerC; KEGG: sdy:SDY_3049 putative transport protein; integral membrane protein TerC 950284 6064724 EcolC_0883 Escherichia coli ATCC 8739 integral membrane protein TerC YP_001723879.1 949571 R 481805 CDS YP_001723880.1 170018926 6064717 complement(950353..951042) 1 NC_010468.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 951042 6064717 EcolC_0884 Escherichia coli ATCC 8739 DNA mismatch repair protein YP_001723880.1 950353 R 481805 CDS YP_001723881.1 170018927 6064710 951727..952257 1 NC_010468.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 952257 6064710 EcolC_0885 Escherichia coli ATCC 8739 dinucleoside polyphosphate hydrolase YP_001723881.1 951727 D 481805 CDS YP_001723882.1 170018928 6064693 952270..954516 1 NC_010468.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein 954516 6064693 EcolC_0886 Escherichia coli ATCC 8739 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein YP_001723882.1 952270 D 481805 CDS YP_001723883.1 170018929 6064668 954667..955542 1 NC_010468.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 955542 6064668 EcolC_0887 Escherichia coli ATCC 8739 prolipoprotein diacylglyceryl transferase YP_001723883.1 954667 D 481805 CDS YP_001723884.1 170018930 6064653 955549..956343 1 NC_010468.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 956343 thyA 6064653 thyA Escherichia coli ATCC 8739 thymidylate synthase YP_001723884.1 955549 D 481805 CDS YP_001723885.1 170018931 6064641 956528..956998 1 NC_010468.1 KEGG: sdy:SDY_3043 prepilin peptidase dependent protein A; hypothetical protein 956998 6064641 EcolC_0889 Escherichia coli ATCC 8739 hypothetical protein YP_001723885.1 956528 D 481805 CDS YP_001723886.1 170018932 6064637 956989..957552 1 NC_010468.1 KEGG: ssn:SSON_2982 prepilin peptidase dependent protein B; hypothetical protein 957552 6064637 EcolC_0890 Escherichia coli ATCC 8739 hypothetical protein YP_001723886.1 956989 D 481805 CDS YP_001723887.1 170018933 6064625 957549..957956 1 NC_010468.1 KEGG: sfv:SFV_2902 hypothetical protein; hypothetical protein 957956 6064625 EcolC_0891 Escherichia coli ATCC 8739 hypothetical protein YP_001723887.1 957549 D 481805 CDS YP_001723888.1 170018934 6064623 957941..958264 1 NC_010468.1 KEGG: sbo:SBO_2713 prepilin peptidase dependent protein C; hypothetical protein 958264 6064623 EcolC_0892 Escherichia coli ATCC 8739 hypothetical protein YP_001723888.1 957941 D 481805 CDS YP_001723889.1 170018935 6064617 958277..961645 1 NC_010468.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 961645 recC 6064617 recC Escherichia coli ATCC 8739 exonuclease V subunit gamma YP_001723889.1 958277 D 481805 CDS YP_001723890.1 170018936 6064615 961821..964709 1 NC_010468.1 PFAM: peptidase M16 domain protein; KEGG: sfv:SFV_2899 protease III; peptidase M16 domain-containing protein 964709 6064615 EcolC_0894 Escherichia coli ATCC 8739 peptidase M16 domain-containing protein YP_001723890.1 961821 D 481805 CDS YP_001723891.1 170018937 6064606 964702..968244 1 NC_010468.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 968244 recB 6064606 recB Escherichia coli ATCC 8739 exonuclease V subunit beta YP_001723891.1 964702 D 481805 CDS YP_001723892.1 170018938 6064598 968244..970070 1 NC_010468.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 970070 recD 6064598 recD Escherichia coli ATCC 8739 exonuclease V subunit alpha YP_001723892.1 968244 D 481805 CDS YP_001723893.1 170018939 6064574 complement(970132..971463) 1 NC_010468.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 971463 6064574 EcolC_0897 Escherichia coli ATCC 8739 N-acetylglutamate synthase YP_001723893.1 970132 R 481805 CDS YP_001723894.1 170018940 6064549 971695..972948 1 NC_010468.1 PFAM: cell wall hydrolase/autolysin; KEGG: sbo:SBO_2707 putative amidase; N-acetylmuramoyl-L-alanine amidase 972948 6064549 EcolC_0898 Escherichia coli ATCC 8739 N-acetylmuramoyl-L-alanine amidase YP_001723894.1 971695 D 481805 CDS YP_001723895.1 170018941 6068719 973527..974624 1 NC_010468.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 974624 mltA 6068719 mltA Escherichia coli ATCC 8739 murein transglycosylase A YP_001723895.1 973527 D 481805 CDS YP_001723896.1 170018942 6068702 974863..975669 1 NC_010468.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ssn:SSON_2969 putative enzyme; UBA/THIF-type NAD/FAD binding protein 975669 6068702 EcolC_0900 Escherichia coli ATCC 8739 UBA/THIF-type NAD/FAD binding protein YP_001723896.1 974863 D 481805 CDS YP_001723897.1 170018943 6068698 complement(975720..976163) 1 NC_010468.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: sdy:SDY_3029 hypothetical protein; cysteine desulfurase, sulfur acceptor subunit CsdE 976163 6068698 EcolC_0901 Escherichia coli ATCC 8739 cysteine desulfurase, sulfur acceptor subunit CsdE YP_001723897.1 975720 R 481805 CDS YP_001723898.1 170018944 6068689 complement(976163..977368) 1 NC_010468.1 TIGRFAM: cysteine desulfurase, catalytic subunit CsdA; PFAM: aminotransferase class V; KEGG: ssn:SSON_2967 hypothetical protein; cysteine sulfinate desulfinase 977368 6068689 EcolC_0902 Escherichia coli ATCC 8739 cysteine sulfinate desulfinase YP_001723898.1 976163 R 481805 CDS YP_001723899.1 170018945 6068684 977560..977787 1 NC_010468.1 PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3027 hypothetical protein; hypothetical protein 977787 6068684 EcolC_0903 Escherichia coli ATCC 8739 hypothetical protein YP_001723899.1 977560 D 481805 CDS YP_001723900.1 170018946 6068677 978138..979055 1 NC_010468.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 979055 6068677 EcolC_0904 Escherichia coli ATCC 8739 DNA-binding transcriptional activator GcvA YP_001723900.1 978138 D 481805 CDS YP_001723901.1 170018947 6068673 979074..979469 1 NC_010468.1 PFAM: protein of unknown function DUF423; KEGG: sdy:SDY_3025 hypothetical protein; hypothetical protein 979469 6068673 EcolC_0905 Escherichia coli ATCC 8739 hypothetical protein YP_001723901.1 979074 D 481805 CDS YP_001723902.1 170018948 6068668 979462..980562 1 NC_010468.1 KEGG: sfv:SFV_2885 hypothetical protein; putative RNA 2'-O-ribose methyltransferase 980562 6068668 EcolC_0906 Escherichia coli ATCC 8739 putative RNA 2'-O-ribose methyltransferase YP_001723902.1 979462 D 481805 CDS YP_001723903.1 170018949 6068663 complement(980606..981337) 1 NC_010468.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 981337 6068663 EcolC_0907 Escherichia coli ATCC 8739 DNA-binding transcriptional activator FucR YP_001723903.1 980606 R 481805 CDS YP_001723904.1 170018950 6068657 complement(981395..981817) 1 NC_010468.1 PFAM: RbsD or FucU transport; KEGG: sdy:SDY_3022 protein of fucose operon; transport protein RbsD/FucU 981817 6068657 EcolC_0908 Escherichia coli ATCC 8739 transport protein RbsD/FucU YP_001723904.1 981395 R 481805 CDS YP_001723905.1 170018951 6068653 complement(981819..983237) 1 NC_010468.1 TIGRFAM: L-fuculokinase; PFAM: carbohydrate kinase FGGY; KEGG: ssn:SSON_2960 L-fuculokinase; L-fuculokinase 983237 6068653 EcolC_0909 Escherichia coli ATCC 8739 L-fuculokinase YP_001723905.1 981819 R 481805 CDS YP_001723906.1 170018952 6068643 complement(983346..985121) 1 NC_010468.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 985121 fucI 6068643 fucI Escherichia coli ATCC 8739 L-fucose isomerase YP_001723906.1 983346 R 481805 CDS YP_001723907.1 170018953 6068636 complement(985154..986470) 1 NC_010468.1 TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_2880 fucose permease; L-fucose transporter 986470 6068636 EcolC_0911 Escherichia coli ATCC 8739 L-fucose transporter YP_001723907.1 985154 R 481805 CDS YP_001723908.1 170018954 6068632 987017..987664 1 NC_010468.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 987664 6068632 EcolC_0912 Escherichia coli ATCC 8739 L-fuculose phosphate aldolase YP_001723908.1 987017 D 481805 CDS YP_001723909.1 170018955 6068627 987689..988840 1 NC_010468.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2956 L-1,2-propanediol oxidoreductase; L-1,2-propanediol oxidoreductase 988840 6068627 EcolC_0913 Escherichia coli ATCC 8739 L-1,2-propanediol oxidoreductase YP_001723909.1 987689 D 481805 CDS YP_001723910.1 170018956 6068625 complement(988895..989650) 1 NC_010468.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 989650 xni 6068625 xni Escherichia coli ATCC 8739 exonuclease IX YP_001723910.1 988895 R 481805 CDS YP_001723911.1 170018957 6068620 complement(989762..991129) 1 NC_010468.1 KEGG: ssn:SSON_2954 L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 991129 6068620 EcolC_0915 Escherichia coli ATCC 8739 L-serine dehydratase 1 YP_001723911.1 989762 R 481805 CDS YP_001723912.1 170018958 6068615 complement(991187..992476) 1 NC_010468.1 TIGRFAM: serine transporter; KEGG: sbo:SBO_2677 probable serine transporter; serine transporter 992476 6068615 EcolC_0916 Escherichia coli ATCC 8739 serine transporter YP_001723912.1 991187 R 481805 CDS YP_001723913.1 170018959 6068613 complement(993033..994397) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2676 hypothetical protein; hypothetical protein 994397 6068613 EcolC_0917 Escherichia coli ATCC 8739 hypothetical protein YP_001723913.1 993033 R 481805 CDS YP_001723914.1 170018960 6068608 complement(994509..995357) 1 NC_010468.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 995357 queF 6068608 queF Escherichia coli ATCC 8739 7-cyano-7-deazaguanine reductase YP_001723914.1 994509 R 481805 CDS YP_001723915.1 170018961 6068604 995425..995970 1 NC_010468.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 995970 6068604 EcolC_0919 Escherichia coli ATCC 8739 SecY interacting protein Syd YP_001723915.1 995425 D 481805 CDS YP_001723916.1 170018962 6068596 996592..996921 1 NC_010468.1 PFAM: protein of unknown function DUF446; KEGG: ssn:SSON_2949 hypothetical protein; hypothetical protein 996921 6068596 EcolC_0920 Escherichia coli ATCC 8739 hypothetical protein YP_001723916.1 996592 D 481805 CDS YP_001723917.1 170018963 6068584 996921..997703 1 NC_010468.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 997703 6068584 EcolC_0921 Escherichia coli ATCC 8739 tRNA pseudouridine synthase C YP_001723917.1 996921 D 481805 CDS YP_001723918.1 170018964 6068578 997721..998170 1 NC_010468.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 998170 6068578 EcolC_0922 Escherichia coli ATCC 8739 flavodoxin YP_001723918.1 997721 D 481805 CDS YP_001723919.1 170018965 6068572 998605..999957 1 NC_010468.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2946 putative transport protein; d-galactonate transporter 999957 6068572 EcolC_0923 Escherichia coli ATCC 8739 d-galactonate transporter YP_001723919.1 998605 D 481805 CDS YP_001723920.1 170018966 6068567 999959..1001299 1 NC_010468.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ssn:SSON_2945 putative glucarate dehydratase; mandelate racemase/muconate lactonizing protein 1001299 6068567 EcolC_0924 Escherichia coli ATCC 8739 mandelate racemase/muconate lactonizing protein YP_001723920.1 999959 D 481805 CDS YP_001723921.1 170018967 6068564 1001320..1002660 1 NC_010468.1 KEGG: sfx:S2994 putative glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein; glucarate dehydratase 1002660 6068564 EcolC_0925 Escherichia coli ATCC 8739 glucarate dehydratase YP_001723921.1 1001320 D 481805 CDS YP_001723922.1 170018968 6068560 complement(1002893..1005649) 1 NC_010468.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 1005649 6068560 EcolC_0926 Escherichia coli ATCC 8739 hybrid sensory histidine kinase BarA YP_001723922.1 1002893 R 481805 CDS YP_001723923.1 170018969 6068545 1005706..1007007 1 NC_010468.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 1007007 rumA 6068545 rumA Escherichia coli ATCC 8739 23S rRNA 5-methyluridine methyltransferase YP_001723923.1 1005706 D 481805 CDS YP_001723924.1 170018970 6068537 1007055..1009289 1 NC_010468.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 1009289 relA 6068537 relA Escherichia coli ATCC 8739 GDP/GTP pyrophosphokinase YP_001723924.1 1007055 D 481805 CDS YP_001723925.1 170018971 6068532 1009367..1009615 1 NC_010468.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 1009615 6068532 EcolC_0929 Escherichia coli ATCC 8739 antitoxin MazE YP_001723925.1 1009367 D 481805 CDS YP_001723926.1 170018972 6068523 1009639..1009950 1 NC_010468.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 1009950 6068523 EcolC_0930 Escherichia coli ATCC 8739 toxin ChpA YP_001723926.1 1009639 D 481805 CDS YP_001723927.1 170018973 6068518 1010021..1010812 1 NC_010468.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1010812 mazG 6068518 mazG Escherichia coli ATCC 8739 nucleoside triphosphate pyrophosphohydrolase YP_001723927.1 1010021 D 481805 CDS YP_001723928.1 170018974 6068514 1011040..1012677 1 NC_010468.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1012677 pyrG 6068514 pyrG Escherichia coli ATCC 8739 CTP synthetase YP_001723928.1 1011040 D 481805 CDS YP_001723929.1 170018975 6068506 1012765..1014063 1 NC_010468.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1014063 eno 6068506 eno Escherichia coli ATCC 8739 phosphopyruvate hydratase YP_001723929.1 1012765 D 481805 CDS YP_001723930.1 170018976 6068495 complement(1014123..1014995) 1 NC_010468.1 PFAM: protein of unknown function DUF477; KEGG: sfv:SFV_2677 hypothetical protein; hypothetical protein 1014995 6068495 EcolC_0934 Escherichia coli ATCC 8739 hypothetical protein YP_001723930.1 1014123 R 481805 CDS YP_001723931.1 170018977 6068492 1015289..1015960 1 NC_010468.1 KEGG: sdy:SDY_2981 hypothetical protein; hypothetical protein 1015960 6068492 EcolC_0935 Escherichia coli ATCC 8739 hypothetical protein YP_001723931.1 1015289 D 481805 CDS YP_001723932.1 170018978 6068482 complement(1017271..1018383) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein 1018383 6068482 EcolC_0936 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001723932.1 1017271 R 481805 CDS YP_001723933.1 170018979 6068454 complement(1020025..1021503) 1 NC_010468.1 PFAM: carbohydrate kinase FGGY; KEGG: sdy:SDY_2978 putative kinase; carbohydrate kinase FGGY 1021503 6068454 EcolC_0937 Escherichia coli ATCC 8739 carbohydrate kinase FGGY YP_001723933.1 1020025 R 481805 CDS YP_001723934.1 170018980 6068442 complement(1021530..1022807) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2927 putative transport protein; major facilitator transporter 1022807 6068442 EcolC_0938 Escherichia coli ATCC 8739 major facilitator transporter YP_001723934.1 1021530 R 481805 CDS YP_001723935.1 170018981 6068435 1023126..1023911 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_2976 putative oxidoreductase; short-chain dehydrogenase/reductase SDR 1023911 6068435 EcolC_0939 Escherichia coli ATCC 8739 short-chain dehydrogenase/reductase SDR YP_001723935.1 1023126 D 481805 CDS YP_001723936.1 170018982 6068425 1023981..1025435 1 NC_010468.1 PFAM: FAD linked oxidase domain protein; KEGG: cko:CKO_04128 hypothetical protein; FAD linked oxidase domain-containing protein 1025435 6068425 EcolC_0940 Escherichia coli ATCC 8739 FAD linked oxidase domain-containing protein YP_001723936.1 1023981 D 481805 CDS YP_001723937.1 170018983 6068413 1025529..1026866 1 NC_010468.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_2924 putative transport protein; major facilitator transporter 1026866 6068413 EcolC_0941 Escherichia coli ATCC 8739 major facilitator transporter YP_001723937.1 1025529 D 481805 CDS YP_001723938.1 170018984 6068400 1026844..1027623 1 NC_010468.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: ssn:SSON_2923 putative transport protein; electron transfer flavoprotein subunit alpha/beta 1027623 6068400 EcolC_0942 Escherichia coli ATCC 8739 electron transfer flavoprotein subunit alpha/beta YP_001723938.1 1026844 D 481805 CDS YP_001723939.1 170018985 6068383 1027620..1028480 1 NC_010468.1 PFAM: Electron transfer flavoprotein alpha subunit; KEGG: ssn:SSON_2922 putative flavoprotein; electron transfer flavoprotein subunit alpha 1028480 6068383 EcolC_0943 Escherichia coli ATCC 8739 electron transfer flavoprotein subunit alpha YP_001723939.1 1027620 D 481805 CDS YP_001723940.1 170018986 6068376 complement(1028628..1029203) 1 NC_010468.1 PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: sdy:SDY_2970 putative anti-terminator regulatory protein; glycerol-3-phosphate responsive antiterminator GlpP 1029203 6068376 EcolC_0944 Escherichia coli ATCC 8739 glycerol-3-phosphate responsive antiterminator GlpP YP_001723940.1 1028628 R 481805 CDS YP_001723941.1 170018987 6068374 complement(1029220..1029480) 1 NC_010468.1 KEGG: sdy:SDY_2969 hypothetical protein; hypothetical protein 1029480 6068374 EcolC_0945 Escherichia coli ATCC 8739 hypothetical protein YP_001723941.1 1029220 R 481805 CDS YP_001723942.1 170018988 6068366 complement(1029471..1030742) 1 NC_010468.1 PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2919 hypothetical protein; electron-transferring-flavoprotein dehydrogenase 1030742 6068366 EcolC_0946 Escherichia coli ATCC 8739 electron-transferring-flavoprotein dehydrogenase YP_001723942.1 1029471 R 481805 CDS YP_001723943.1 170018989 6068359 complement(1030820..1031185) 1 NC_010468.1 KEGG: sbo:SBO_2649 putative 6-pyruvoyl tetrahydrobiopterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase; queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; 6-pyruvoyl-tetrahydropterin synthase 1031185 6068359 EcolC_0947 Escherichia coli ATCC 8739 6-pyruvoyl-tetrahydropterin synthase YP_001723943.1 1030820 R 481805 CDS YP_001723944.1 170018990 6068352 1031501..1033300 1 NC_010468.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 1033300 cysJ 6068352 cysJ Escherichia coli ATCC 8739 sulfite reductase subunit alpha YP_001723944.1 1031501 D 481805 CDS YP_001723945.1 170018991 6068350 1033300..1035012 1 NC_010468.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 1035012 6068350 EcolC_0949 Escherichia coli ATCC 8739 sulfite reductase subunit beta YP_001723945.1 1033300 D 481805 CDS YP_001723946.1 170018992 6068347 1035087..1035821 1 NC_010468.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 1035821 6068347 EcolC_0950 Escherichia coli ATCC 8739 phosphoadenosine phosphosulfate reductase YP_001723946.1 1035087 D 481805 CDS YP_001723947.1 170018993 6068341 1036180..1038846 1 NC_010468.1 KEGG: gsu:GSU1384 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; hypothetical protein 1038846 6068341 EcolC_0951 Escherichia coli ATCC 8739 hypothetical protein YP_001723947.1 1036180 D 481805 CDS YP_001723948.1 170018994 6068332 1039261..1040769 1 NC_010468.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein 1040769 6068332 EcolC_0952 Escherichia coli ATCC 8739 hypothetical protein YP_001723948.1 1039261 D 481805 CDS YP_001723949.1 170018995 6068315 1040762..1041244 1 NC_010468.1 TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2; KEGG: gsu:GSU1386 hypothetical protein; CRISPR-associated Cse2 family protein 1041244 6068315 EcolC_0953 Escherichia coli ATCC 8739 CRISPR-associated Cse2 family protein YP_001723949.1 1040762 D 481805 CDS YP_001723950.1 170018996 6068312 1041257..1042348 1 NC_010468.1 TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CRISPR-associated protein CT1975; KEGG: gsu:GSU1387 CRISPR-associated CT1975 family protein; CRISPR-associated Cse4 family protein 1042348 6068312 EcolC_0954 Escherichia coli ATCC 8739 CRISPR-associated Cse4 family protein YP_001723950.1 1041257 D 481805 CDS YP_001723951.1 170018997 6068303 1042351..1043025 1 NC_010468.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: gsu:GSU1388 CRISPR-associated CT1976 family protein; CRISPR-associated Cas5 family protein 1043025 6068303 EcolC_0955 Escherichia coli ATCC 8739 CRISPR-associated Cas5 family protein YP_001723951.1 1042351 D 481805 CDS YP_001723952.1 170018998 6068298 1043012..1043611 1 NC_010468.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: sdy:SDY_2955 hypothetical protein; CRISPR-associated Cse3 family protein 1043611 6068298 EcolC_0956 Escherichia coli ATCC 8739 CRISPR-associated Cse3 family protein YP_001723952.1 1043012 D 481805 CDS YP_001723953.1 170018999 6068290 1043627..1044544 1 NC_010468.1 TIGRFAM: CRISPR-associated protein Cas1; KEGG: stt:t2839 hypothetical protein; CRISPR-associated Cas1 family protein 1044544 6068290 EcolC_0957 Escherichia coli ATCC 8739 CRISPR-associated Cas1 family protein YP_001723953.1 1043627 D 481805 CDS YP_001723954.1 170019000 6068280 1044546..1044830 1 NC_010468.1 TIGRFAM: CRISPR-associated protein Cas2; KEGG: sdy:SDY_2953 hypothetical protein; hypothetical protein 1044830 6068280 EcolC_0958 Escherichia coli ATCC 8739 hypothetical protein YP_001723954.1 1044546 D 481805 CDS YP_001723955.1 170019001 6068256 complement(1046266..1047303) 1 NC_010468.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 1047303 6068256 EcolC_0959 Escherichia coli ATCC 8739 alkaline phosphatase isozyme conversion aminopeptidase YP_001723955.1 1046266 R 481805 CDS YP_001723956.1 170019002 6068236 1047555..1048463 1 NC_010468.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 1048463 6068236 EcolC_0960 Escherichia coli ATCC 8739 sulfate adenylyltransferase subunit 2 YP_001723956.1 1047555 D 481805 CDS YP_001723957.1 170019003 6068229 1048465..1049892 1 NC_010468.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 1049892 cysN 6068229 cysN Escherichia coli ATCC 8739 sulfate adenylyltransferase subunit 1 YP_001723957.1 1048465 D 481805 CDS YP_001723958.1 170019004 6068220 1049892..1050497 1 NC_010468.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 1050497 6068220 EcolC_0962 Escherichia coli ATCC 8739 adenylylsulfate kinase YP_001723958.1 1049892 D 481805 CDS YP_001723959.1 170019005 6068216 1050547..1050870 1 NC_010468.1 KEGG: sdy:SDY_2948 putative cytochrome oxidase subunit; hypothetical protein 1050870 6068216 EcolC_0963 Escherichia coli ATCC 8739 hypothetical protein YP_001723959.1 1050547 D 481805 CDS YP_001723960.1 170019006 6068212 1051064..1051375 1 NC_010468.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 1051375 ftsB 6068212 ftsB Escherichia coli ATCC 8739 cell division protein FtsB YP_001723960.1 1051064 D 481805 CDS YP_001723961.1 170019007 6068206 1051394..1052104 1 NC_010468.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1052104 ispD 6068206 ispD Escherichia coli ATCC 8739 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001723961.1 1051394 D 481805 CDS YP_001723962.1 170019008 6068194 1052104..1052583 1 NC_010468.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1052583 ispF 6068194 ispF Escherichia coli ATCC 8739 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001723962.1 1052104 D 481805 CDS YP_001723963.1 170019009 6068181 1052580..1053629 1 NC_010468.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 1053629 truD 6068181 truD Escherichia coli ATCC 8739 tRNA pseudouridine synthase D YP_001723963.1 1052580 D 481805 CDS YP_001723964.1 170019010 6068171 1053610..1054371 1 NC_010468.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 1054371 surE 6068171 surE Escherichia coli ATCC 8739 stationary phase survival protein SurE YP_001723964.1 1053610 D 481805 CDS YP_001723965.1 170019011 6068153 1054365..1054991 1 NC_010468.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1054991 pcm 6068153 pcm Escherichia coli ATCC 8739 protein-L-isoaspartate O-methyltransferase YP_001723965.1 1054365 D 481805 CDS YP_001723966.1 170019012 6068029 1055131..1056270 1 NC_010468.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 1056270 nlpD 6068029 nlpD Escherichia coli ATCC 8739 lipoprotein NlpD YP_001723966.1 1055131 D 481805 CDS YP_001723967.1 170019013 6068014 1056333..1057325 1 NC_010468.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 1057325 6068014 EcolC_0971 Escherichia coli ATCC 8739 RNA polymerase sigma factor RpoS YP_001723967.1 1056333 D 481805 CDS YP_001723968.1 170019014 6067975 complement(1057419..1058783) 1 NC_010468.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 1058783 6067975 EcolC_0972 Escherichia coli ATCC 8739 inner membrane permease YgbN YP_001723968.1 1057419 R 481805 CDS YP_001723969.1 170019015 6067951 complement(1058872..1059648) 1 NC_010468.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sbo:SBO_2781 hypothetical protein; hypothetical protein 1059648 6067951 EcolC_0973 Escherichia coli ATCC 8739 hypothetical protein YP_001723969.1 1058872 R 481805 CDS YP_001723970.1 170019016 6067930 complement(1059653..1060291) 1 NC_010468.1 PFAM: class II aldolase/adducin family protein; KEGG: sbo:SBO_2782 putative epimerase/aldolase; putative aldolase 1060291 6067930 EcolC_0974 Escherichia coli ATCC 8739 putative aldolase YP_001723970.1 1059653 R 481805 CDS YP_001723971.1 170019017 6067922 complement(1060288..1061550) 1 NC_010468.1 PFAM: type III effector Hrp-dependent outers; KEGG: ssn:SSON_2885 hypothetical protein; Hrp-dependent type III effector protein 1061550 6067922 EcolC_0975 Escherichia coli ATCC 8739 Hrp-dependent type III effector protein YP_001723971.1 1060288 R 481805 CDS YP_001723972.1 170019018 6067893 complement(1061547..1062455) 1 NC_010468.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ssn:SSON_2884 putative dehydrogenase; 2-hydroxy-3-oxopropionate reductase 1062455 6067893 EcolC_0976 Escherichia coli ATCC 8739 2-hydroxy-3-oxopropionate reductase YP_001723972.1 1061547 R 481805 CDS YP_001723973.1 170019019 6067882 1062651..1063418 1 NC_010468.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sbo:SBO_2785 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 1063418 6067882 EcolC_0977 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001723973.1 1062651 D 481805 CDS YP_001723974.1 170019020 6067877 join(1063619..1063873,1063873..1064316) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 1064316 6067877 EcolC_0978 Escherichia coli ATCC 8739 insertion element protein YP_001723974.1 1063619 D 481805 CDS YP_001723975.1 170019021 6067846 complement(1064408..1066969) 1 NC_010468.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1066969 6067846 EcolC_0979 Escherichia coli ATCC 8739 DNA mismatch repair protein MutS YP_001723975.1 1064408 R 481805 CDS YP_001723976.1 170019022 6067815 1067256..1067609 1 NC_010468.1 KEGG: sbo:SBO_2788 hypothetical protein; hypothetical protein 1067609 6067815 EcolC_0980 Escherichia coli ATCC 8739 hypothetical protein YP_001723976.1 1067256 D 481805 CDS YP_001723977.1 170019023 6067810 complement(1067646..1069724) 1 NC_010468.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2789 formate hydrogen-lyase transcriptional activator for FdhF, hyc and hyp operons; NifA subfamily transcriptional regulator 1069724 6067810 EcolC_0981 Escherichia coli ATCC 8739 NifA subfamily transcriptional regulator YP_001723977.1 1067646 R 481805 CDS YP_001723978.1 170019024 6067804 complement(1069798..1070808) 1 NC_010468.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: ssn:SSON_2877 HypE; hydrogenase expression/formation protein HypE 1070808 6067804 EcolC_0982 Escherichia coli ATCC 8739 hydrogenase expression/formation protein HypE YP_001723978.1 1069798 R 481805 CDS YP_001723979.1 170019025 6067799 complement(1070805..1071926) 1 NC_010468.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: sbo:SBO_2791 HypD; hydrogenase expression/formation protein HypD 1071926 6067799 EcolC_0983 Escherichia coli ATCC 8739 hydrogenase expression/formation protein HypD YP_001723979.1 1070805 R 481805 CDS YP_001723980.1 170019026 6067796 complement(1071926..1072198) 1 NC_010468.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 1072198 6067796 EcolC_0984 Escherichia coli ATCC 8739 hydrogenase assembly chaperone YP_001723980.1 1071926 R 481805 CDS YP_001723981.1 170019027 6067791 complement(1072189..1073061) 1 NC_010468.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 1073061 6067791 EcolC_0985 Escherichia coli ATCC 8739 hydrogenase nickel incorporation protein HypB YP_001723981.1 1072189 R 481805 CDS YP_001723982.1 170019028 6067788 complement(1073065..1073415) 1 NC_010468.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 1073415 hypA 6067788 hypA Escherichia coli ATCC 8739 hydrogenase nickel incorporation protein YP_001723982.1 1073065 R 481805 CDS YP_001723983.1 170019029 6067776 1073627..1074088 1 NC_010468.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 1074088 6067776 EcolC_0987 Escherichia coli ATCC 8739 formate hydrogenlyase regulatory protein HycA YP_001723983.1 1073627 D 481805 CDS YP_001723984.1 170019030 6067770 1074213..1074824 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2779 probable small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex); 4Fe-4S ferredoxin 1074824 6067770 EcolC_0988 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001723984.1 1074213 D 481805 CDS YP_001723985.1 170019031 6067766 1074821..1076647 1 NC_010468.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 1076647 6067766 EcolC_0989 Escherichia coli ATCC 8739 formate hydrogenlyase subunit 3 YP_001723985.1 1074821 D 481805 CDS YP_001723986.1 170019032 6067758 1076650..1077573 1 NC_010468.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: sbo:SBO_2796 membrane-spanning protein of hydrogenase 3; respiratory-chain NADH dehydrogenase subunit 1 1077573 6067758 EcolC_0990 Escherichia coli ATCC 8739 respiratory-chain NADH dehydrogenase subunit 1 YP_001723986.1 1076650 D 481805 CDS YP_001723987.1 170019033 6067744 1077591..1079300 1 NC_010468.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: sbo:SBO_2797 large subunit of hydrogenase 3; NADH dehydrogenase (ubiquinone) 30 kDa subunit 1079300 6067744 EcolC_0991 Escherichia coli ATCC 8739 NADH dehydrogenase (ubiquinone) 30 kDa subunit YP_001723987.1 1077591 D 481805 CDS YP_001723988.1 170019034 6067741 1079310..1079852 1 NC_010468.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 1079852 6067741 EcolC_0992 Escherichia coli ATCC 8739 formate hydrogenlyase complex iron-sulfur subunit YP_001723988.1 1079310 D 481805 CDS YP_001723989.1 170019035 6067739 1079852..1080619 1 NC_010468.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: sfv:SFV_2784 hydrogenase activity; NADH ubiquinone oxidoreductase 20 kDa subunit 1080619 6067739 EcolC_0993 Escherichia coli ATCC 8739 NADH ubiquinone oxidoreductase 20 kDa subunit YP_001723989.1 1079852 D 481805 CDS YP_001723990.1 170019036 6067736 1080616..1081026 1 NC_010468.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: sbo:SBO_2800 processing of large subunit (HycE) of hydrogenase 3; formate hydrogenlyase maturation HycH 1081026 6067736 EcolC_0994 Escherichia coli ATCC 8739 formate hydrogenlyase maturation HycH YP_001723990.1 1080616 D 481805 CDS YP_001723991.1 170019037 6067730 1081019..1081489 1 NC_010468.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 1081489 hycI 6067730 hycI Escherichia coli ATCC 8739 hydrogenase 3 maturation protease YP_001723991.1 1081019 D 481805 CDS YP_001723992.1 170019038 6067726 complement(1081648..1083072) 1 NC_010468.1 PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_2860 6-phospho-beta-glucosidase, cryptic; cryptic 6-phospho-beta-glucosidase 1083072 6067726 EcolC_0996 Escherichia coli ATCC 8739 cryptic 6-phospho-beta-glucosidase YP_001723992.1 1081648 R 481805 CDS YP_001723993.1 170019039 6067723 complement(1083081..1084538) 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 1084538 6067723 EcolC_0997 Escherichia coli ATCC 8739 PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_001723993.1 1083081 R 481805 CDS YP_001723994.1 170019040 6067720 1084795..1085808 1 NC_010468.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ssn:SSON_2858 ascBF operon repressor; LacI family transcriptional regulator 1085808 6067720 EcolC_0998 Escherichia coli ATCC 8739 LacI family transcriptional regulator YP_001723994.1 1084795 D 481805 CDS YP_001723995.1 170019041 6067711 1085957..1086484 1 NC_010468.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 1086484 6067711 EcolC_0999 Escherichia coli ATCC 8739 electron transport protein HydN YP_001723995.1 1085957 D 481805 CDS YP_001723996.1 170019042 6067708 1086637..1088889 1 NC_010468.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: ssn:SSON_2856 transcriptional regulatory protein; (NiFe) hydrogenase maturation protein HypF 1088889 6067708 EcolC_1000 Escherichia coli ATCC 8739 (NiFe) hydrogenase maturation protein HypF YP_001723996.1 1086637 D 481805 CDS YP_001723997.1 170019043 6067699 complement(1089017..1090150) 1 NC_010468.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 1090150 6067699 EcolC_1001 Escherichia coli ATCC 8739 nitric oxide reductase YP_001723997.1 1089017 R 481805 CDS YP_001723998.1 170019044 6067674 complement(1090147..1091586) 1 NC_010468.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 1091586 6067674 EcolC_1002 Escherichia coli ATCC 8739 anaerobic nitric oxide reductase flavorubredoxin YP_001723998.1 1090147 R 481805 CDS YP_001723999.1 170019045 6067653 1091773..1093287 1 NC_010468.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 1093287 6067653 EcolC_1003 Escherichia coli ATCC 8739 anaerobic nitric oxide reductase transcriptional regulator YP_001723999.1 1091773 D 481805 CDS YP_001724000.1 170019046 6067627 complement(1093284..1094249) 1 NC_010468.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 1094249 gutQ 6067627 gutQ Escherichia coli ATCC 8739 D-arabinose 5-phosphate isomerase YP_001724000.1 1093284 R 481805 CDS YP_001724001.1 170019047 6067617 complement(1094242..1095015) 1 NC_010468.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 1095015 srlR 6067617 srlR Escherichia coli ATCC 8739 DNA-binding transcriptional repressor SrlR YP_001724001.1 1094242 R 481805 CDS YP_001724002.1 170019048 6067588 complement(1095082..1095441) 1 NC_010468.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 1095441 6067588 EcolC_1006 Escherichia coli ATCC 8739 DNA-binding transcriptional activator GutM YP_001724002.1 1095082 R 481805 CDS YP_001724003.1 170019049 6067579 complement(1095547..1096326) 1 NC_010468.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 1096326 6067579 EcolC_1007 Escherichia coli ATCC 8739 sorbitol-6-phosphate dehydrogenase YP_001724003.1 1095547 R 481805 CDS YP_001724004.1 170019050 6067546 complement(1096330..1096701) 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 1096701 6067546 EcolC_1008 Escherichia coli ATCC 8739 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_001724004.1 1096330 R 481805 CDS YP_001724005.1 170019051 6067534 complement(1096712..1097671) 1 NC_010468.1 KEGG: sbo:SBO_2815 PTS system glucitol/sorbitol-specific IIB component and second of two IIC components; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein; PTS system glucitol/sorbitol-specific transporter subunit IIBC 1097671 6067534 EcolC_1009 Escherichia coli ATCC 8739 PTS system glucitol/sorbitol-specific transporter subunit IIBC YP_001724005.1 1096712 R 481805 CDS YP_001724006.1 170019052 6067520 complement(1097668..1098231) 1 NC_010468.1 TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: sdy:SDY_2898 PTS system, glucitol/sorbitol-specific IIC component; PTS system glucitol/sorbitol-specific transporter subunit IIC 1098231 6067520 EcolC_1010 Escherichia coli ATCC 8739 PTS system glucitol/sorbitol-specific transporter subunit IIC YP_001724006.1 1097668 R 481805 CDS YP_001724007.1 170019053 6067506 1098487..1099572 1 NC_010468.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 1099572 6067506 EcolC_1011 Escherichia coli ATCC 8739 murein hydrolase B YP_001724007.1 1098487 D 481805 CDS YP_001724008.1 170019054 6067461 1099717..1100214 1 NC_010468.1 PFAM: CinA domain protein; KEGG: ssn:SSON_2844 hypothetical protein; competence damage-inducible protein A 1100214 6067461 EcolC_1012 Escherichia coli ATCC 8739 competence damage-inducible protein A YP_001724008.1 1099717 D 481805 CDS YP_001724009.1 170019055 6067411 1100294..1101355 1 NC_010468.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1101355 recA 6067411 recA Escherichia coli ATCC 8739 recombinase A YP_001724009.1 1100294 D 481805 CDS YP_001724010.1 170019056 6067382 1101424..1101924 1 NC_010468.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1101924 recX 6067382 recX Escherichia coli ATCC 8739 recombination regulator RecX YP_001724010.1 1101424 D 481805 CDS YP_001724011.1 170019057 6067350 1102052..1104682 1 NC_010468.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1104682 alaS 6067350 alaS Escherichia coli ATCC 8739 alanyl-tRNA synthetase YP_001724011.1 1102052 D 481805 CDS YP_001724012.1 170019058 6067339 1104917..1105102 1 NC_010468.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 1105102 6067339 EcolC_1016 Escherichia coli ATCC 8739 carbon storage regulator YP_001724012.1 1104917 D 481805 CDS YP_001724013.1 170019059 6067008 1106560..1107126 1 NC_010468.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 1107126 6067008 EcolC_1017 Escherichia coli ATCC 8739 fructose-1-phosphatase YP_001724013.1 1106560 D 481805 CDS YP_001724014.1 170019060 6066952 1107123..1107551 1 NC_010468.1 KEGG: sfv:SFV_2815 hypothetical protein; hypothetical protein 1107551 6066952 EcolC_1018 Escherichia coli ATCC 8739 hypothetical protein YP_001724014.1 1107123 D 481805 CDS YP_001724015.1 170019061 6066930 1107624..1109180 1 NC_010468.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 1109180 6066930 EcolC_1019 Escherichia coli ATCC 8739 glutamate--cysteine ligase YP_001724015.1 1107624 D 481805 CDS YP_001724016.1 170019062 6066897 1109330..1109845 1 NC_010468.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1109845 6066897 EcolC_1020 Escherichia coli ATCC 8739 S-ribosylhomocysteinase YP_001724016.1 1109330 D 481805 CDS YP_001724017.1 170019063 6066876 complement(1109909..1111447) 1 NC_010468.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2830 probably membrane translocase; EmrB/QacA family drug resistance transporter 1111447 6066876 EcolC_1021 Escherichia coli ATCC 8739 EmrB/QacA family drug resistance transporter YP_001724017.1 1109909 R 481805 CDS YP_001724018.1 170019064 6066872 complement(1111464..1112636) 1 NC_010468.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_2832 multidrug resistance secretion protein; efflux pump membrane protein 1112636 6066872 EcolC_1022 Escherichia coli ATCC 8739 efflux pump membrane protein YP_001724018.1 1111464 R 481805 CDS YP_001724019.1 170019065 6066837 complement(1112763..1113293) 1 NC_010468.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 1113293 6066837 EcolC_1023 Escherichia coli ATCC 8739 transcriptional repressor MprA YP_001724019.1 1112763 R 481805 CDS YP_001724020.1 170019066 6066835 complement(1113384..1113719) 1 NC_010468.1 KEGG: sbo:SBO_2834 hypothetical protein; hypothetical protein 1113719 6066835 EcolC_1024 Escherichia coli ATCC 8739 hypothetical protein YP_001724020.1 1113384 R 481805 CDS YP_001724021.1 170019067 6066785 complement(1113709..1114446) 1 NC_010468.1 PFAM: AzlC family protein; KEGG: ssn:SSON_2826 hypothetical protein; AzlC family protein 1114446 6066785 EcolC_1025 Escherichia coli ATCC 8739 AzlC family protein YP_001724021.1 1113709 R 481805 CDS YP_001724022.1 170019068 6066756 complement(1114570..1115754) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2836 permease; major facilitator transporter 1115754 6066756 EcolC_1026 Escherichia coli ATCC 8739 major facilitator transporter YP_001724022.1 1114570 R 481805 CDS YP_001724023.1 170019069 6066751 complement(1116046..1117038) 1 NC_010468.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 1117038 proX 6066751 proX Escherichia coli ATCC 8739 glycine betaine transporter periplasmic subunit YP_001724023.1 1116046 R 481805 CDS YP_001724024.1 170019070 6066745 complement(1117096..1118160) 1 NC_010468.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 1118160 6066745 EcolC_1028 Escherichia coli ATCC 8739 glycine betaine transporter membrane protein YP_001724024.1 1117096 R 481805 CDS YP_001724025.1 170019071 6066741 complement(1118153..1119355) 1 NC_010468.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 1119355 6066741 EcolC_1029 Escherichia coli ATCC 8739 glycine betaine transporter ATP-binding subunit YP_001724025.1 1118153 R 481805 CDS YP_001724026.1 170019072 6066736 complement(1119709..1120668) 1 NC_010468.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 1120668 nrdF 6066736 nrdF Escherichia coli ATCC 8739 ribonucleotide-diphosphate reductase subunit beta YP_001724026.1 1119709 R 481805 CDS YP_001724027.1 170019073 6066721 complement(1120678..1122783) 1 NC_010468.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1122783 6066721 EcolC_1031 Escherichia coli ATCC 8739 ribonucleotide-diphosphate reductase subunit alpha YP_001724027.1 1120678 R 481805 CDS YP_001724028.1 170019074 6066667 complement(1122795..1123205) 1 NC_010468.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 1123205 nrdI 6066667 nrdI Escherichia coli ATCC 8739 ribonucleotide reductase stimulatory protein YP_001724028.1 1122795 R 481805 CDS YP_001724029.1 170019075 6066650 complement(1123202..1123447) 1 NC_010468.1 TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: sbo:SBO_2844 glutaredoxin-like protein; glutaredoxin-like protein 1123447 6066650 EcolC_1033 Escherichia coli ATCC 8739 glutaredoxin-like protein YP_001724029.1 1123202 R 481805 CDS YP_001724030.1 170019076 6066640 complement(1123695..1124024) 1 NC_010468.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2863 hypothetical protein; hypothetical protein 1124024 6066640 EcolC_1034 Escherichia coli ATCC 8739 hypothetical protein YP_001724030.1 1123695 R 481805 CDS YP_001724031.1 170019077 6066624 1124176..1124520 1 NC_010468.1 KEGG: sbo:SBO_2848 hypothetical protein; hypothetical protein 1124520 6066624 EcolC_1035 Escherichia coli ATCC 8739 hypothetical protein YP_001724031.1 1124176 D 481805 CDS YP_001724032.1 170019078 6066617 complement(1124557..1125006) 1 NC_010468.1 PFAM: protein of unknown function DUF1144; KEGG: sbo:SBO_2849 hypothetical protein; hypothetical protein 1125006 6066617 EcolC_1036 Escherichia coli ATCC 8739 hypothetical protein YP_001724032.1 1124557 R 481805 CDS YP_001724033.1 170019079 6066601 1125675..1126079 1 NC_010468.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sdy:SDY_2859 DNA-binding protein; nucleoid-associated DNA binding protein 1126079 6066601 EcolC_1037 Escherichia coli ATCC 8739 nucleoid-associated DNA binding protein YP_001724033.1 1125675 D 481805 CDS YP_001724034.1 170019080 6066574 complement(1126126..1126650) 1 NC_010468.1 SMART: Rhodanese domain protein; KEGG: ssn:SSON_2812 hypothetical protein; rhodanese domain-containing protein 1126650 6066574 EcolC_1038 Escherichia coli ATCC 8739 rhodanese domain-containing protein YP_001724034.1 1126126 R 481805 CDS YP_001724035.1 170019081 6066533 complement(1126660..1126959) 1 NC_010468.1 PFAM: regulatory protein ArsR; KEGG: sbo:SBO_2852 hypothetical protein; ArsR family transcriptional regulator 1126959 6066533 EcolC_1039 Escherichia coli ATCC 8739 ArsR family transcriptional regulator YP_001724035.1 1126660 R 481805 CDS YP_001724036.1 170019082 6066508 1127142..1127300 1 NC_010468.1 PFAM: protein of unknown function UPF0057; KEGG: sdy:SDY_2856 hypothetical protein; hypothetical protein 1127300 6066508 EcolC_1040 Escherichia coli ATCC 8739 hypothetical protein YP_001724036.1 1127142 D 481805 CDS YP_001724037.1 170019083 6066492 1127384..1127833 1 NC_010468.1 PFAM: Peptidoglycan-binding LysM; transport-associated; SMART: Transport-associated and nodulation region; KEGG: sdy:SDY_2855 hypothetical protein; LysM domain/BON superfamily protein 1127833 6066492 EcolC_1041 Escherichia coli ATCC 8739 LysM domain/BON superfamily protein YP_001724037.1 1127384 D 481805 CDS YP_001724038.1 170019084 6066486 complement(1127834..1128496) 1 NC_010468.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 1128496 6066486 EcolC_1042 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator CsiR YP_001724038.1 1127834 R 481805 CDS YP_001724039.1 170019085 6066479 complement(1128517..1129917) 1 NC_010468.1 TIGRFAM: GABA permease; PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2853 transport permease protein of gamma-aminobutyrate; gamma-aminobutyrate transporter 1129917 6066479 EcolC_1043 Escherichia coli ATCC 8739 gamma-aminobutyrate transporter YP_001724039.1 1128517 R 481805 CDS YP_001724040.1 170019086 6066436 complement(1130155..1131435) 1 NC_010468.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 1131435 6066436 EcolC_1044 Escherichia coli ATCC 8739 4-aminobutyrate aminotransferase YP_001724040.1 1130155 R 481805 CDS YP_001724041.1 170019087 6066422 complement(1131449..1132897) 1 NC_010468.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 1132897 gabD 6066422 gabD Escherichia coli ATCC 8739 succinate-semialdehyde dehydrogenase I YP_001724041.1 1131449 R 481805 CDS YP_001724042.1 170019088 6066419 complement(1132920..1134188) 1 NC_010468.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 1134188 6066419 EcolC_1046 Escherichia coli ATCC 8739 hydroxyglutarate oxidase YP_001724042.1 1132920 R 481805 CDS YP_001724043.1 170019089 6066405 complement(1134207..1135184) 1 NC_010468.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 1135184 6066405 EcolC_1047 Escherichia coli ATCC 8739 hypothetical protein YP_001724043.1 1134207 R 481805 CDS YP_001724044.1 170019090 6066394 complement(1135932..1137773) 1 NC_010468.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sfv:SFV_2845 putative enzyme; alpha amylase 1137773 6066394 EcolC_1048 Escherichia coli ATCC 8739 alpha amylase YP_001724044.1 1135932 R 481805 CDS YP_001724045.1 170019091 6066305 1140960..1141103 1 NC_010468.1 KEGG: ssn:SSON_2797 hypothetical protein; hypothetical protein 1141103 6066305 EcolC_1051 Escherichia coli ATCC 8739 hypothetical protein YP_001724045.1 1140960 D 481805 CDS YP_001724046.1 170019092 6066296 1141442..1146022 1 NC_010468.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sdy:SDY_1204 putative ATP-binding component of a transport system; outer membrane autotransporter 1146022 6066296 EcolC_1052 Escherichia coli ATCC 8739 outer membrane autotransporter YP_001724046.1 1141442 D 481805 CDS YP_001724047.1 170019093 6066280 complement(1146686..1149019) 1 NC_010468.1 KEGG: stt:t2656 hypothetical protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 protein; TOPRIM domain protein; P4 alpha zinc-binding domain protein; primase P4; SMART: Toprim sub domain protein; P4 family phage/plasmid primase 1149019 6066280 EcolC_1053 Escherichia coli ATCC 8739 P4 family phage/plasmid primase YP_001724047.1 1146686 R 481805 CDS YP_001724048.1 170019094 6066265 complement(1149034..1149354) 1 NC_010468.1 KEGG: sbo:SBO_4166 putative protein encoded in prophage; putative prophage protein 1149354 6066265 EcolC_1054 Escherichia coli ATCC 8739 putative prophage protein YP_001724048.1 1149034 R 481805 CDS YP_001724049.1 170019095 6066258 complement(1149490..1149945) 1 NC_010468.1 KEGG: stt:t2654 hypothetical protein; hypothetical protein 1149945 6066258 EcolC_1055 Escherichia coli ATCC 8739 hypothetical protein YP_001724049.1 1149490 R 481805 CDS YP_001724050.1 170019096 6066200 complement(1149938..1150225) 1 NC_010468.1 KEGG: stt:t2653 hypothetical protein; hypothetical protein 1150225 6066200 EcolC_1056 Escherichia coli ATCC 8739 hypothetical protein YP_001724050.1 1149938 R 481805 CDS YP_001724051.1 170019097 6066125 complement(1150218..1150808) 1 NC_010468.1 KEGG: sbo:SBO_4168 putative bacteriophage protein; putative bacteriophage protein 1150808 6066125 EcolC_1057 Escherichia coli ATCC 8739 putative bacteriophage protein YP_001724051.1 1150218 R 481805 CDS YP_001724052.1 170019098 6066109 complement(1150805..1151071) 1 NC_010468.1 PFAM: Prophage CP4-57 regulatory; KEGG: sbo:SBO_4169 hypothetical protein; phage transcriptional regulator, AlpA 1151071 6066109 EcolC_1058 Escherichia coli ATCC 8739 phage transcriptional regulator, AlpA YP_001724052.1 1150805 R 481805 CDS YP_001724053.1 170019099 6066106 1151623..1152357 1 NC_010468.1 KEGG: sbo:SBO_4170 hypothetical protein; hypothetical protein 1152357 6066106 EcolC_1059 Escherichia coli ATCC 8739 hypothetical protein YP_001724053.1 1151623 D 481805 CDS YP_001724054.1 170019100 6066093 1152354..1152854 1 NC_010468.1 PFAM: transcriptional activator Ogr/delta; KEGG: stt:t2649 hypothetical protein; transcriptional activator Ogr/delta 1152854 6066093 EcolC_1060 Escherichia coli ATCC 8739 transcriptional activator Ogr/delta YP_001724054.1 1152354 D 481805 CDS YP_001724055.1 170019101 6066090 1152928..1153500 1 NC_010468.1 PFAM: polarity suppression protein; KEGG: stt:t2648 hypothetical protein; polarity suppression protein 1153500 6066090 EcolC_1061 Escherichia coli ATCC 8739 polarity suppression protein YP_001724055.1 1152928 D 481805 CDS YP_001724056.1 170019102 6066076 1153980..1155683 1 NC_010468.1 hypothetical protein 1155683 6066076 EcolC_1062 Escherichia coli ATCC 8739 hypothetical protein YP_001724056.1 1153980 D 481805 CDS YP_001724057.1 170019103 6066036 complement(1155680..1156876) 1 NC_010468.1 PFAM: integrase family protein; KEGG: esa:ESA_00630 hypothetical protein; integrase family protein 1156876 6066036 EcolC_1063 Escherichia coli ATCC 8739 integrase family protein YP_001724057.1 1155680 R 481805 CDS YP_001724058.1 170019104 6065996 complement(1157638..1158120) 1 NC_010468.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1158120 smpB 6065996 smpB Escherichia coli ATCC 8739 SsrA-binding protein YP_001724058.1 1157638 R 481805 CDS YP_001724059.1 170019105 6065964 1158252..1158728 1 NC_010468.1 PFAM: cyclase/dehydrase; KEGG: sdy:SDY_2792 hypothetical protein; hypothetical protein 1158728 6065964 EcolC_1065 Escherichia coli ATCC 8739 hypothetical protein YP_001724059.1 1158252 D 481805 CDS YP_001724060.1 170019106 6065916 1158718..1159008 1 NC_010468.1 PFAM: protein of unknown function UPF0125; KEGG: sbo:SBO_2753 hypothetical protein; hypothetical protein 1159008 6065916 EcolC_1066 Escherichia coli ATCC 8739 hypothetical protein YP_001724060.1 1158718 D 481805 CDS YP_001724061.1 170019107 6065903 complement(1159070..1159411) 1 NC_010468.1 PFAM: SmpA/OmlA domain protein; KEGG: cko:CKO_03939 hypothetical protein; hypothetical protein 1159411 6065903 EcolC_1067 Escherichia coli ATCC 8739 hypothetical protein YP_001724061.1 1159070 R 481805 CDS YP_001724062.1 170019108 6065877 complement(1159560..1161221) 1 NC_010468.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: ssn:SSON_2772 protein used in recombination and DNA repair; recombination and repair protein 1161221 6065877 EcolC_1068 Escherichia coli ATCC 8739 recombination and repair protein YP_001724062.1 1159560 R 481805 CDS YP_001724063.1 170019109 6065837 complement(1161307..1162185) 1 NC_010468.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1162185 ppnK 6065837 ppnK Escherichia coli ATCC 8739 inorganic polyphosphate/ATP-NAD kinase YP_001724063.1 1161307 R 481805 CDS YP_001724064.1 170019110 6065816 1162308..1162901 1 NC_010468.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1162901 6065816 EcolC_1070 Escherichia coli ATCC 8739 heat shock protein GrpE YP_001724064.1 1162308 D 481805 CDS YP_001724065.1 170019111 6065788 complement(1162956..1164197) 1 NC_010468.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: ssn:SSON_2769 uncharacterized CBS domain-containing protein; hypothetical protein 1164197 6065788 EcolC_1071 Escherichia coli ATCC 8739 hypothetical protein YP_001724065.1 1162956 R 481805 CDS YP_001724066.1 170019112 6065767 complement(1164263..1165129) 1 NC_010468.1 PFAM: cytochrome c assembly protein; KEGG: sdy:SDY_2785 hypothetical protein; cytochrome c assembly protein 1165129 6065767 EcolC_1072 Escherichia coli ATCC 8739 cytochrome c assembly protein YP_001724066.1 1164263 R 481805 CDS YP_001724067.1 170019113 6065703 1165221..1166582 1 NC_010468.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 1166582 6065703 EcolC_1073 Escherichia coli ATCC 8739 signal recognition particle protein YP_001724067.1 1165221 D 481805 CDS YP_001724068.1 170019114 6065667 1166719..1166967 1 NC_010468.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1166967 rpsP 6065667 rpsP Escherichia coli ATCC 8739 30S ribosomal protein S16 YP_001724068.1 1166719 D 481805 CDS YP_001724069.1 170019115 6065653 1166986..1167534 1 NC_010468.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1167534 rimM 6065653 rimM Escherichia coli ATCC 8739 16S rRNA-processing protein RimM YP_001724069.1 1166986 D 481805 CDS YP_001724070.1 170019116 6065648 1167565..1168332 1 NC_010468.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1168332 trmD 6065648 trmD Escherichia coli ATCC 8739 tRNA (guanine-N(1)-)-methyltransferase YP_001724070.1 1167565 D 481805 CDS YP_001724071.1 170019117 6065606 1168374..1168721 1 NC_010468.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1168721 rplS 6065606 rplS Escherichia coli ATCC 8739 50S ribosomal protein L19 YP_001724071.1 1168374 D 481805 CDS YP_001724072.1 170019118 6065579 complement(1168797..1169279) 1 NC_010468.1 PFAM: OmpA/MotB domain protein; KEGG: sbo:SBO_2741 putative outer membrane protein; putative outer membrane lipoprotein 1169279 6065579 EcolC_1078 Escherichia coli ATCC 8739 putative outer membrane lipoprotein YP_001724072.1 1168797 R 481805 CDS YP_001724073.1 170019119 6065565 complement(1169295..1170521) 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_2761 hypothetical protein; hypothetical protein 1170521 6065565 EcolC_1079 Escherichia coli ATCC 8739 hypothetical protein YP_001724073.1 1169295 R 481805 CDS YP_001724074.1 170019120 6065557 complement(1170511..1171029) 1 NC_010468.1 KEGG: ssn:SSON_2755 hypothetical protein; hypothetical protein 1171029 6065557 EcolC_1080 Escherichia coli ATCC 8739 hypothetical protein YP_001724074.1 1170511 R 481805 CDS YP_001724075.1 170019121 6065553 complement(1171179..1171544) 1 NC_010468.1 KEGG: sfv:SFV_2869 hypothetical protein; hypothetical protein 1171544 6065553 EcolC_1081 Escherichia coli ATCC 8739 hypothetical protein YP_001724075.1 1171179 R 481805 CDS YP_001724076.1 170019122 6065529 1171754..1172824 1 NC_010468.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1172824 6065529 EcolC_1082 Escherichia coli ATCC 8739 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001724076.1 1171754 D 481805 CDS YP_001724077.1 170019123 6065511 1172835..1173956 1 NC_010468.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 1173956 tyrA 6065511 tyrA Escherichia coli ATCC 8739 bifunctional chorismate mutase/prephenate dehydrogenase YP_001724077.1 1172835 D 481805 CDS YP_001724078.1 170019124 6065490 complement(1173999..1175159) 1 NC_010468.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 1175159 pheA 6065490 pheA Escherichia coli ATCC 8739 bifunctional chorismate mutase/prephenate dehydratase YP_001724078.1 1173999 R 481805 CDS YP_001724079.1 170019125 6065488 complement(1175408..1175758) 1 NC_010468.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 1175758 6065488 EcolC_1085 Escherichia coli ATCC 8739 translation inhibitor protein RaiA YP_001724079.1 1175408 R 481805 CDS YP_001724080.1 170019126 6065472 complement(1176029..1176766) 1 NC_010468.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 1176766 6065472 EcolC_1086 Escherichia coli ATCC 8739 outer membrane protein assembly complex subunit YfiO YP_001724080.1 1176029 R 481805 CDS YP_001724081.1 170019127 6065468 1176901..1177881 1 NC_010468.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 1177881 rluD 6065468 rluD Escherichia coli ATCC 8739 23S rRNA pseudouridine synthase D YP_001724081.1 1176901 D 481805 CDS YP_001724082.1 170019128 6065374 1177878..1178609 1 NC_010468.1 PFAM: protein of unknown function DUF152; KEGG: sdy:SDY_2836 hypothetical protein; hypothetical protein 1178609 6065374 EcolC_1088 Escherichia coli ATCC 8739 hypothetical protein YP_001724082.1 1177878 D 481805 CDS YP_001724083.1 170019129 6065349 1178739..1181312 1 NC_010468.1 KEGG: sbo:SBO_2627 heat shock protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; protein disaggregation chaperone 1181312 6065349 EcolC_1089 Escherichia coli ATCC 8739 protein disaggregation chaperone YP_001724083.1 1178739 D 481805 CDS YP_001724084.1 170019130 6066567 1187176..1188474 1 NC_010468.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2830 alpha-ketoglutarate permease; alpha-ketoglutarate transporter 1188474 6066567 EcolC_1090 Escherichia coli ATCC 8739 alpha-ketoglutarate transporter YP_001724084.1 1187176 D 481805 CDS YP_001724085.1 170019131 6066409 complement(1188471..1188794) 1 NC_010468.1 KEGG: sfv:SFV_2649 hypothetical protein; hypothetical protein 1188794 6066409 EcolC_1091 Escherichia coli ATCC 8739 hypothetical protein YP_001724085.1 1188471 R 481805 CDS YP_001724086.1 170019132 6066313 complement(1188840..1190195) 1 NC_010468.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 1190195 pssA 6066313 pssA Escherichia coli ATCC 8739 phosphatidylserine synthase YP_001724086.1 1188840 R 481805 CDS YP_001724087.1 170019133 6065932 complement(1190309..1192969) 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: sbo:SBO_2616 hypothetical protein; N-acetyltransferase GCN5 1192969 6065932 EcolC_1093 Escherichia coli ATCC 8739 N-acetyltransferase GCN5 YP_001724087.1 1190309 R 481805 CDS YP_001724088.1 170019134 6065073 complement(1193001..1193699) 1 NC_010468.1 PFAM: DTW domain containing protein; KEGG: sdy:SDY_2826 hypothetical protein; DTW domain-containing protein 1193699 6065073 EcolC_1094 Escherichia coli ATCC 8739 DTW domain-containing protein YP_001724088.1 1193001 R 481805 CDS YP_001724089.1 170019135 6065929 complement(1193768..1194187) 1 NC_010468.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sdy:SDY_2825 putative thioredoxin-like protein; thioredoxin 2 1194187 6065929 EcolC_1095 Escherichia coli ATCC 8739 thioredoxin 2 YP_001724089.1 1193768 R 481805 CDS YP_001724090.1 170019136 6064688 1194394..1195431 1 NC_010468.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sdy:SDY_2824 hypothetical protein; putative methyltransferase 1195431 6064688 EcolC_1096 Escherichia coli ATCC 8739 putative methyltransferase YP_001724090.1 1194394 D 481805 CDS YP_001724091.1 170019137 6066177 complement(1195479..1196168) 1 NC_010468.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1196168 6066177 EcolC_1097 Escherichia coli ATCC 8739 uracil-DNA glycosylase YP_001724091.1 1195479 R 481805 CDS YP_001724092.1 170019138 6064849 1196473..1196856 1 NC_010468.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 1196856 6064849 EcolC_1098 Escherichia coli ATCC 8739 autonomous glycyl radical cofactor GrcA YP_001724092.1 1196473 D 481805 CDS YP_001724093.1 170019139 6064988 complement(1196912..1197499) 1 NC_010468.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ssn:SSON_2704 hypothetical protein; neutral amino-acid efflux protein 1197499 6064988 EcolC_1099 Escherichia coli ATCC 8739 neutral amino-acid efflux protein YP_001724093.1 1196912 R 481805 CDS YP_001724094.1 170019140 6065620 1197603..1198484 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_2703 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 1198484 6065620 EcolC_1100 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001724094.1 1197603 D 481805 CDS YP_001724095.1 170019141 6067359 complement(1198693..1200027) 1 NC_010468.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 1200027 6067359 EcolC_1101 Escherichia coli ATCC 8739 ATP-dependent RNA helicase SrmB YP_001724095.1 1198693 R 481805 CDS YP_001724096.1 170019142 6065235 1200159..1200896 1 NC_010468.1 PFAM: methyltransferase small; KEGG: sfv:SFV_2638 putative enzyme; methyltransferase small 1200896 6065235 EcolC_1102 Escherichia coli ATCC 8739 methyltransferase small YP_001724096.1 1200159 D 481805 CDS YP_001724097.1 170019143 6065232 complement(1200881..1202503) 1 NC_010468.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 1202503 6065232 EcolC_1103 Escherichia coli ATCC 8739 L-aspartate oxidase YP_001724097.1 1200881 R 481805 CDS YP_001724098.1 170019144 6065230 1202911..1203486 1 NC_010468.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 1203486 6065230 EcolC_1104 Escherichia coli ATCC 8739 RNA polymerase sigma factor RpoE YP_001724098.1 1202911 D 481805 CDS YP_001724099.1 170019145 6066184 1203519..1204169 1 NC_010468.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: sdy:SDY_2813 sigma-E factor, negative regulatory protein; anti-RNA polymerase sigma factor SigE 1204169 6066184 EcolC_1105 Escherichia coli ATCC 8739 anti-RNA polymerase sigma factor SigE YP_001724099.1 1203519 D 481805 CDS YP_001724100.1 170019146 6066707 1204169..1205125 1 NC_010468.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 1205125 rseB 6066707 rseB Escherichia coli ATCC 8739 periplasmic negative regulator of sigmaE YP_001724100.1 1204169 D 481805 CDS YP_001724101.1 170019147 6065017 1205122..1205601 1 NC_010468.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 1205601 6065017 EcolC_1107 Escherichia coli ATCC 8739 SoxR reducing system protein RseC YP_001724101.1 1205122 D 481805 CDS YP_001724102.1 170019148 6066887 1205799..1207598 1 NC_010468.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1207598 6066887 EcolC_1108 Escherichia coli ATCC 8739 GTP-binding protein LepA YP_001724102.1 1205799 D 481805 CDS YP_001724103.1 170019149 6067912 1207614..1208588 1 NC_010468.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 1208588 6067912 EcolC_1109 Escherichia coli ATCC 8739 signal peptidase I YP_001724103.1 1207614 D 481805 CDS YP_001724104.1 170019150 6065398 1208860..1209540 1 NC_010468.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1209540 rnc 6065398 rnc Escherichia coli ATCC 8739 ribonuclease III YP_001724104.1 1208860 D 481805 CDS YP_001724105.1 170019151 6066524 1209537..1210442 1 NC_010468.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1210442 era 6066524 era Escherichia coli ATCC 8739 GTP-binding protein Era YP_001724105.1 1209537 D 481805 CDS YP_001724106.1 170019152 6067917 1210454..1211182 1 NC_010468.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1211182 recO 6067917 recO Escherichia coli ATCC 8739 DNA repair protein RecO YP_001724106.1 1210454 D 481805 CDS YP_001724107.1 170019153 6067933 1211194..1211925 1 NC_010468.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1211925 6067933 EcolC_1113 Escherichia coli ATCC 8739 pyridoxine 5'-phosphate synthase YP_001724107.1 1211194 D 481805 CDS YP_001724108.1 170019154 6067937 1211925..1212305 1 NC_010468.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1212305 acpS 6067937 acpS Escherichia coli ATCC 8739 4'-phosphopantetheinyl transferase YP_001724108.1 1211925 D 481805 CDS YP_001724109.1 170019155 6065203 complement(1213000..1213260) 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_2590 hypothetical protein; 4Fe-4S ferredoxin 1213260 6065203 EcolC_1115 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001724109.1 1213000 R 481805 CDS YP_001724110.1 170019156 6067947 complement(1213316..1214164) 1 NC_010468.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sbo:SBO_2589 hypothetical protein; putative DNA-binding transcriptional regulator 1214164 6067947 EcolC_1116 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001724110.1 1213316 R 481805 CDS YP_001724111.1 170019157 6067958 1214373..1215008 1 NC_010468.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: sfv:SFV_2608 hypothetical protein; hypothetical protein 1215008 6067958 EcolC_1117 Escherichia coli ATCC 8739 hypothetical protein YP_001724111.1 1214373 D 481805 CDS YP_001724112.1 170019158 6067970 1215066..1215569 1 NC_010468.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sbo:SBO_2587 putative deaminase; tRNA-specific adenosine deaminase 1215569 6067970 EcolC_1118 Escherichia coli ATCC 8739 tRNA-specific adenosine deaminase YP_001724112.1 1215066 D 481805 CDS YP_001724113.1 170019159 6067971 complement(1215566..1217122) 1 NC_010468.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 1217122 6067971 EcolC_1119 Escherichia coli ATCC 8739 putative transglycosylase YP_001724113.1 1215566 R 481805 CDS YP_001724114.1 170019160 6067973 1217380..1221267 1 NC_010468.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 1221267 6067973 EcolC_1120 Escherichia coli ATCC 8739 phosphoribosylformylglycinamidine synthase YP_001724114.1 1217380 D 481805 CDS YP_001724115.1 170019161 6067978 1221825..1223252 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_2746 putative 2-component sensor protein; integral membrane sensor signal transduction histidine kinase 1223252 6067978 EcolC_1121 Escherichia coli ATCC 8739 integral membrane sensor signal transduction histidine kinase YP_001724115.1 1221825 D 481805 CDS YP_001724116.1 170019162 6067981 1223417..1224130 1 NC_010468.1 KEGG: sfv:SFV_2603 putative alpha helix protein; hypothetical protein 1224130 6067981 EcolC_1122 Escherichia coli ATCC 8739 hypothetical protein YP_001724116.1 1223417 D 481805 CDS YP_001724117.1 170019163 6067969 1224120..1225454 1 NC_010468.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2582 putative 2-component transcriptional regulator; two component sigma-54 specific Fis family transcriptional regulator 1225454 6067969 EcolC_1123 Escherichia coli ATCC 8739 two component sigma-54 specific Fis family transcriptional regulator YP_001724117.1 1224120 D 481805 CDS YP_001724118.1 170019164 6067988 1225515..1225853 1 NC_010468.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 1225853 6067988 EcolC_1124 Escherichia coli ATCC 8739 nitrogen regulatory protein P-II 1 YP_001724118.1 1225515 D 481805 CDS YP_001724119.1 170019165 6067991 complement(1225898..1227088) 1 NC_010468.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 1227088 6067991 EcolC_1125 Escherichia coli ATCC 8739 nitric oxide dioxygenase YP_001724119.1 1225898 R 481805 CDS YP_001724120.1 170019166 6067996 1227416..1228669 1 NC_010468.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1228669 glyA 6067996 glyA Escherichia coli ATCC 8739 serine hydroxymethyltransferase YP_001724120.1 1227416 D 481805 CDS YP_001724121.1 170019167 6068004 complement(1228867..1230060) 1 NC_010468.1 PFAM: ROK family protein; KEGG: sbo:SBO_2578 putative NAGC-like transcriptional regulator; ROK family protein 1230060 6068004 EcolC_1127 Escherichia coli ATCC 8739 ROK family protein YP_001724121.1 1228867 R 481805 CDS YP_001724122.1 170019168 6068006 1230178..1233459 1 NC_010468.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sbo:SBO_2577 hypothetical protein; hypothetical protein 1233459 6068006 EcolC_1128 Escherichia coli ATCC 8739 hypothetical protein YP_001724122.1 1230178 D 481805 CDS YP_001724123.1 170019169 6068007 1233556..1234539 1 NC_010468.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sfv:SFV_2596 putative LacI-type transcriptional regulator; periplasmic binding protein/LacI transcriptional regulator 1234539 6068007 EcolC_1129 Escherichia coli ATCC 8739 periplasmic binding protein/LacI transcriptional regulator YP_001724123.1 1233556 D 481805 CDS YP_001724124.1 170019170 6068018 1234562..1236073 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_2573 putative ATP-binding component of a transport system; ABC transporter-like protein 1236073 6068018 EcolC_1130 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001724124.1 1234562 D 481805 CDS YP_001724125.1 170019171 6068023 1236098..1237096 1 NC_010468.1 PFAM: inner-membrane translocator; KEGG: ssn:SSON_2629 putative transport system permease protein; monosaccharide-transporting ATPase 1237096 6068023 EcolC_1131 Escherichia coli ATCC 8739 monosaccharide-transporting ATPase YP_001724125.1 1236098 D 481805 CDS YP_001724126.1 170019172 6068026 1237162..1238223 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_2628 putative oxidoreductase; alcohol dehydrogenase 1238223 6068026 EcolC_1132 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001724126.1 1237162 D 481805 CDS YP_001724127.1 170019173 6067993 1238235..1239107 1 NC_010468.1 PFAM: Aldose 1-epimerase; KEGG: ssn:SSON_2627 hypothetical protein; aldose 1-epimerase 1239107 6067993 EcolC_1133 Escherichia coli ATCC 8739 aldose 1-epimerase YP_001724127.1 1238235 D 481805 CDS YP_001724128.1 170019174 6068028 complement(1239155..1239577) 1 NC_010468.1 PFAM: DoxX family protein; KEGG: sfx:S2762 hypothetical protein; DoxX family protein 1239577 6068028 EcolC_1134 Escherichia coli ATCC 8739 DoxX family protein YP_001724128.1 1239155 R 481805 CDS YP_001724129.1 170019175 6068037 complement(1239674..1240876) 1 NC_010468.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2624 ferredoxin reductase subunit of phenylpropionate dioxygenase; phenylpropionate dioxygenase ferredoxin reductase subunit 1240876 6068037 EcolC_1135 Escherichia coli ATCC 8739 phenylpropionate dioxygenase ferredoxin reductase subunit YP_001724129.1 1239674 R 481805 CDS YP_001724130.1 170019176 6068039 complement(1240886..1241698) 1 NC_010468.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 1241698 6068039 EcolC_1136 Escherichia coli ATCC 8739 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_001724130.1 1240886 R 481805 CDS YP_001724131.1 170019177 6068043 complement(1241695..1242015) 1 NC_010468.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_2622 ferredoxin subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase ferredoxin subunit 1242015 6068043 EcolC_1137 Escherichia coli ATCC 8739 3-phenylpropionate dioxygenase ferredoxin subunit YP_001724131.1 1241695 R 481805 CDS YP_001724132.1 170019178 6067174 complement(1242015..1242533) 1 NC_010468.1 PFAM: aromatic-ring-hydroxylating dioxygenase beta subunit; KEGG: sfx:S2758 small terminal subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase subunit beta 1242533 6067174 EcolC_1138 Escherichia coli ATCC 8739 3-phenylpropionate dioxygenase subunit beta YP_001724132.1 1242015 R 481805 CDS YP_001724133.1 170019179 6068044 complement(1242530..1243891) 1 NC_010468.1 PFAM: Rieske [2Fe-2S] domain protein; Aromatic-ring-hydroxylating dioxygenase, alpha subunit-like; KEGG: ssn:SSON_2620 large terminal subunit of phenylpropionate dioxygenase; aromatic-ring-hydroxylating dioxygenase subunit alpha-like protein 1243891 6068044 EcolC_1139 Escherichia coli ATCC 8739 aromatic-ring-hydroxylating dioxygenase subunit alpha-like protein YP_001724133.1 1242530 R 481805 CDS YP_001724134.1 170019180 6068050 1244027..1244917 1 NC_010468.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 1244917 6068050 EcolC_1140 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator HcaR YP_001724134.1 1244027 D 481805 CDS YP_001724135.1 170019181 6068051 1245077..1246216 1 NC_010468.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 1246216 6068051 EcolC_1141 Escherichia coli ATCC 8739 putative 3-phenylpropionic acid transporter YP_001724135.1 1245077 D 481805 CDS YP_001724136.1 170019182 6068053 complement(1246208..1247488) 1 NC_010468.1 PFAM: PRD domain protein; KEGG: sbo:SBO_2559 hypothetical protein; stationary phase inducible protein CsiE 1247488 6068053 EcolC_1142 Escherichia coli ATCC 8739 stationary phase inducible protein CsiE YP_001724136.1 1246208 R 481805 CDS YP_001724137.1 170019183 6068054 complement(1247679..1248533) 1 NC_010468.1 KEGG: sdy:SDY_2730 putative enzyme; putative enzyme 1248533 6068054 EcolC_1143 Escherichia coli ATCC 8739 putative enzyme YP_001724137.1 1247679 R 481805 CDS YP_001724138.1 170019184 6067927 complement(1248678..1249481) 1 NC_010468.1 PFAM: inositol monophosphatase; KEGG: sbo:SBO_2557 SuhB; inositol monophosphatase 1249481 6067927 EcolC_1144 Escherichia coli ATCC 8739 inositol monophosphatase YP_001724138.1 1248678 R 481805 CDS YP_001724139.1 170019185 6065229 1249600..1250340 1 NC_010468.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sbo:SBO_2556 putative ATP synthase beta subunit; RNA methyltransferase 1250340 6065229 EcolC_1145 Escherichia coli ATCC 8739 RNA methyltransferase YP_001724139.1 1249600 D 481805 CDS YP_001724140.1 170019186 6065655 1250610..1251098 1 NC_010468.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 1251098 6065655 EcolC_1146 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator IscR YP_001724140.1 1250610 D 481805 CDS YP_001724141.1 170019187 6068059 1251339..1252553 1 NC_010468.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 1252553 6068059 EcolC_1147 Escherichia coli ATCC 8739 cysteine desulfurase YP_001724141.1 1251339 D 481805 CDS YP_001724142.1 170019188 6068060 1252581..1252967 1 NC_010468.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: sdy:SDY_2725 hypothetical protein; scaffold protein 1252967 6068060 EcolC_1148 Escherichia coli ATCC 8739 scaffold protein YP_001724142.1 1252581 D 481805 CDS YP_001724143.1 170019189 6068062 1252984..1253307 1 NC_010468.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 1253307 iscA 6068062 iscA Escherichia coli ATCC 8739 iron-sulfur cluster assembly protein YP_001724143.1 1252984 D 481805 CDS YP_001724144.1 170019190 6068065 1253403..1253918 1 NC_010468.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 1253918 hscB 6068065 hscB Escherichia coli ATCC 8739 co-chaperone HscB YP_001724144.1 1253403 D 481805 CDS YP_001724145.1 170019191 6068069 1253935..1255785 1 NC_010468.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1255785 hscA 6068069 hscA Escherichia coli ATCC 8739 chaperone protein HscA YP_001724145.1 1253935 D 481805 CDS YP_001724146.1 170019192 6068057 1255787..1256122 1 NC_010468.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: sbo:SBO_2549 [2FE-2S] ferredoxin, electron carrer protein; 2Fe-2S ferredoxin 1256122 6068057 EcolC_1152 Escherichia coli ATCC 8739 2Fe-2S ferredoxin YP_001724146.1 1255787 D 481805 CDS YP_001724147.1 170019193 6068076 1256134..1256334 1 NC_010468.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: sdy:SDY_2720 hypothetical protein; hypothetical protein 1256334 6068076 EcolC_1153 Escherichia coli ATCC 8739 hypothetical protein YP_001724147.1 1256134 D 481805 CDS YP_001724148.1 170019194 6068081 1256392..1257675 1 NC_010468.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 1257675 6068081 EcolC_1154 Escherichia coli ATCC 8739 aminopeptidase B YP_001724148.1 1256392 D 481805 CDS YP_001724149.1 170019195 6068084 1257817..1258593 1 NC_010468.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 1258593 6068084 EcolC_1155 Escherichia coli ATCC 8739 enhanced serine sensitivity protein SseB YP_001724149.1 1257817 D 481805 CDS YP_001724150.1 170019196 6068086 complement(1259411..1260256) 1 NC_010468.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 1260256 sseA 6068086 sseA Escherichia coli ATCC 8739 3-mercaptopyruvate sulfurtransferase YP_001724150.1 1259411 R 481805 CDS YP_001724151.1 170019197 6068090 1260463..1265424 1 NC_010468.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: ssn:SSON_2602 hypothetical protein; alpha-2-macroglobulin domain-containing protein 1265424 6068090 EcolC_1157 Escherichia coli ATCC 8739 alpha-2-macroglobulin domain-containing protein YP_001724151.1 1260463 D 481805 CDS YP_001724152.1 170019198 6068092 1265425..1267737 1 NC_010468.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 1267737 6068092 EcolC_1158 Escherichia coli ATCC 8739 penicillin-binding protein 1C YP_001724152.1 1265425 D 481805 CDS YP_001724153.1 170019199 6068096 1267886..1268317 1 NC_010468.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1268317 ndk 6068096 ndk Escherichia coli ATCC 8739 nucleoside diphosphate kinase YP_001724153.1 1267886 D 481805 CDS YP_001724154.1 170019200 6068099 1268467..1269621 1 NC_010468.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1269621 6068099 EcolC_1160 Escherichia coli ATCC 8739 ribosomal RNA large subunit methyltransferase N YP_001724154.1 1268467 D 481805 CDS YP_001724155.1 170019201 6068082 1269906..1270919 1 NC_010468.1 PFAM: helix-turn-helix domain protein; KEGG: sdy:SDY_2712 hypothetical protein; cytoskeletal protein RodZ 1270919 6068082 EcolC_1161 Escherichia coli ATCC 8739 cytoskeletal protein RodZ YP_001724155.1 1269906 D 481805 CDS YP_001724156.1 170019202 6068100 1270946..1272064 1 NC_010468.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1272064 ispG 6068100 ispG Escherichia coli ATCC 8739 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001724156.1 1270946 D 481805 CDS YP_001724157.1 170019203 6068101 1272175..1273449 1 NC_010468.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1273449 hisS 6068101 hisS Escherichia coli ATCC 8739 histidyl-tRNA synthetase YP_001724157.1 1272175 D 481805 CDS YP_001724158.1 170019204 6068102 1273467..1274087 1 NC_010468.1 KEGG: sdy:SDY_2709 hypothetical protein; hypothetical protein 1274087 6068102 EcolC_1164 Escherichia coli ATCC 8739 hypothetical protein YP_001724158.1 1273467 D 481805 CDS YP_001724159.1 170019205 6065489 1274098..1275276 1 NC_010468.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 1275276 6065489 EcolC_1165 Escherichia coli ATCC 8739 outer membrane protein assembly complex subunit YfgL YP_001724159.1 1274098 D 481805 CDS YP_001724160.1 170019206 6065502 1275394..1276866 1 NC_010468.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1276866 engA 6065502 engA Escherichia coli ATCC 8739 GTP-binding protein EngA YP_001724160.1 1275394 D 481805 CDS YP_001724161.1 170019207 6066301 1276935..1277150 1 NC_010468.1 PFAM: protein of unknown function DUF1407; KEGG: sdy:SDY_2706 hypothetical protein; hypothetical protein 1277150 6066301 EcolC_1167 Escherichia coli ATCC 8739 hypothetical protein YP_001724161.1 1276935 D 481805 CDS YP_001724162.1 170019208 6066491 complement(1277147..1278517) 1 NC_010468.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1278517 xseA 6066491 xseA Escherichia coli ATCC 8739 exodeoxyribonuclease VII large subunit YP_001724162.1 1277147 R 481805 CDS YP_001724163.1 170019209 6066644 1278679..1280145 1 NC_010468.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 1280145 6066644 EcolC_1169 Escherichia coli ATCC 8739 inosine 5'-monophosphate dehydrogenase YP_001724163.1 1278679 D 481805 CDS YP_001724164.1 170019210 6067244 1280214..1281791 1 NC_010468.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1281791 guaA 6067244 guaA Escherichia coli ATCC 8739 GMP synthase YP_001724164.1 1280214 D 481805 CDS YP_001724165.1 170019211 6064607 complement(1281884..1282423) 1 NC_010468.1 KEGG: sdy:SDY_2702 hypothetical protein; hypothetical protein 1282423 6064607 EcolC_1171 Escherichia coli ATCC 8739 hypothetical protein YP_001724165.1 1281884 R 481805 CDS YP_001724166.1 170019212 6064878 complement(1282439..1282954) 1 NC_010468.1 PFAM: 17 kDa surface antigen; KEGG: ssn:SSON_2587 putative outer membrane lipoprotein; 17 kDa surface antigen 1282954 6064878 EcolC_1172 Escherichia coli ATCC 8739 17 kDa surface antigen YP_001724166.1 1282439 R 481805 CDS YP_001724167.1 170019213 6064994 1283811..1286054 1 NC_010468.1 PFAM: EAL domain protein; MASE1 domain protein; SMART: GGDEF domain containing protein; KEGG: ssn:SSON_2585 putative cytochrome c-type biogenesis protein; diguanylate cyclase/phosphodiesterase 1286054 6064994 EcolC_1173 Escherichia coli ATCC 8739 diguanylate cyclase/phosphodiesterase YP_001724167.1 1283811 D 481805 CDS YP_001724168.1 170019214 6065826 complement(1286093..1287634) 1 NC_010468.1 PFAM: Ppx/GppA phosphatase; KEGG: ssn:SSON_2584 exopolyphosphatase; exopolyphosphatase 1287634 6065826 EcolC_1174 Escherichia coli ATCC 8739 exopolyphosphatase YP_001724168.1 1286093 R 481805 CDS YP_001724169.1 170019215 6067151 complement(1287639..1289705) 1 NC_010468.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 1289705 6067151 EcolC_1175 Escherichia coli ATCC 8739 polyphosphate kinase YP_001724169.1 1287639 R 481805 CDS YP_001724170.1 170019216 6066039 complement(1289876..1290514) 1 NC_010468.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1290514 purN 6066039 purN Escherichia coli ATCC 8739 phosphoribosylglycinamide formyltransferase YP_001724170.1 1289876 R 481805 CDS YP_001724171.1 170019217 6064917 complement(1290514..1291551) 1 NC_010468.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1291551 6064917 EcolC_1177 Escherichia coli ATCC 8739 phosphoribosylaminoimidazole synthetase YP_001724171.1 1290514 R 481805 CDS YP_001724172.1 170019218 6064905 1291876..1292502 1 NC_010468.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1292502 upp 6064905 upp Escherichia coli ATCC 8739 uracil phosphoribosyltransferase YP_001724172.1 1291876 D 481805 CDS YP_001724173.1 170019219 6064741 1292588..1293877 1 NC_010468.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_2579 uracil transport; uracil transporter 1293877 6064741 EcolC_1179 Escherichia coli ATCC 8739 uracil transporter YP_001724173.1 1292588 D 481805 CDS YP_001724174.1 170019220 6064680 1293927..1294673 1 NC_010468.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 1294673 6064680 EcolC_1180 Escherichia coli ATCC 8739 DNA replication initiation factor YP_001724174.1 1293927 D 481805 CDS YP_001724175.1 170019221 6067690 complement(1294811..1295170) 1 NC_010468.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sdy:SDY_2684 putative oxidoreductase; arsenate reductase 1295170 6067690 EcolC_1181 Escherichia coli ATCC 8739 arsenate reductase YP_001724175.1 1294811 R 481805 CDS YP_001724176.1 170019222 6067344 complement(1295191..1296654) 1 NC_010468.1 PFAM: peptidase M48 Ste24p; KEGG: sfv:SFV_2539 hypothetical protein; peptidase M48 Ste24p 1296654 6067344 EcolC_1182 Escherichia coli ATCC 8739 peptidase M48 Ste24p YP_001724176.1 1295191 R 481805 CDS YP_001724177.1 170019223 6066923 1296867..1297928 1 NC_010468.1 PFAM: protein of unknown function UPF0118; KEGG: sdy:SDY_2682 putative permease; hypothetical protein 1297928 6066923 EcolC_1183 Escherichia coli ATCC 8739 hypothetical protein YP_001724177.1 1296867 D 481805 CDS YP_001724178.1 170019224 6066900 complement(1297966..1298814) 1 NC_010468.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 1298814 focB 6066900 focB Escherichia coli ATCC 8739 putative formate transporter YP_001724178.1 1297966 R 481805 CDS YP_001724179.1 170019225 6066794 complement(1298836..1300848) 1 NC_010468.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_2572 putative 2-component regulator, interaction with sigma 54; NifA subfamily transcriptional regulator 1300848 6066794 EcolC_1185 Escherichia coli ATCC 8739 NifA subfamily transcriptional regulator YP_001724179.1 1298836 R 481805 CDS YP_001724180.1 170019226 6066154 complement(1300878..1301291) 1 NC_010468.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: ssn:SSON_2571 putative protein processing element; formate hydrogenlyase maturation HycH 1301291 6066154 EcolC_1186 Escherichia coli ATCC 8739 formate hydrogenlyase maturation HycH YP_001724180.1 1300878 R 481805 CDS YP_001724181.1 170019227 6065393 complement(1301284..1302042) 1 NC_010468.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ssn:SSON_2570 hydrogenase 4 Fe-S subunit; NADH ubiquinone oxidoreductase 20 kDa subunit 1302042 6065393 EcolC_1187 Escherichia coli ATCC 8739 NADH ubiquinone oxidoreductase 20 kDa subunit YP_001724181.1 1301284 R 481805 CDS YP_001724182.1 170019228 6066219 complement(1302039..1302578) 1 NC_010468.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 1302578 6066219 EcolC_1188 Escherichia coli ATCC 8739 hydrogenase 4 subunit H YP_001724182.1 1302039 R 481805 CDS YP_001724183.1 170019229 6066315 complement(1302588..1304255) 1 NC_010468.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: ssn:SSON_2568 hydrogenase 4 subunit; NADH dehydrogenase (ubiquinone) 30 kDa subunit 1304255 6066315 EcolC_1189 Escherichia coli ATCC 8739 NADH dehydrogenase (ubiquinone) 30 kDa subunit YP_001724183.1 1302588 R 481805 CDS YP_001724184.1 170019230 6065804 complement(1304245..1305825) 1 NC_010468.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2567 hydrogenase 4 membrane subunit; hydrogenase 4 subunit F 1305825 6065804 EcolC_1190 Escherichia coli ATCC 8739 hydrogenase 4 subunit F YP_001724184.1 1304245 R 481805 CDS YP_001724185.1 170019231 6065673 complement(1305830..1306480) 1 NC_010468.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 1306480 hyfE 6065673 hyfE Escherichia coli ATCC 8739 hydrogenase 4 membrane subunit YP_001724185.1 1305830 R 481805 CDS YP_001724186.1 170019232 6065531 complement(1306492..1307844) 1 NC_010468.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: sfv:SFV_2529 hydrogenase 4 membrane subunit; hydrogenase 4 subunit D 1307844 6065531 EcolC_1192 Escherichia coli ATCC 8739 hydrogenase 4 subunit D YP_001724186.1 1306492 R 481805 CDS YP_001724187.1 170019233 6065193 complement(1308904..1310922) 1 NC_010468.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2563 hydrogenase 4 membrane subunit; hydrogenase 4 subunit B 1310922 6065193 EcolC_1194 Escherichia coli ATCC 8739 hydrogenase 4 subunit B YP_001724187.1 1308904 R 481805 CDS YP_001724188.1 170019234 6065028 complement(1310922..1311539) 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2526 hydrogenase 4 Fe-S subunit; 4Fe-4S ferredoxin 1311539 6065028 EcolC_1195 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001724188.1 1310922 R 481805 CDS YP_001724189.1 170019235 6064853 complement(1311792..1312262) 1 NC_010468.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 1312262 bcp 6064853 bcp Escherichia coli ATCC 8739 thioredoxin-dependent thiol peroxidase YP_001724189.1 1311792 R 481805 CDS YP_001724190.1 170019236 6064771 complement(1312262..1312834) 1 NC_010468.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 1312834 gcvR 6064771 gcvR Escherichia coli ATCC 8739 glycine cleavage system transcriptional repressor YP_001724190.1 1312262 R 481805 CDS YP_001724191.1 170019237 6064663 1312980..1313858 1 NC_010468.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1313858 6064663 EcolC_1198 Escherichia coli ATCC 8739 dihydrodipicolinate synthase YP_001724191.1 1312980 D 481805 CDS YP_001724192.1 170019238 6067645 1313875..1314909 1 NC_010468.1 PFAM: NlpBDapX family lipoprotein; KEGG: ssn:SSON_2558 lipoprotein-34; lipoprotein 1314909 6067645 EcolC_1199 Escherichia coli ATCC 8739 lipoprotein YP_001724192.1 1313875 D 481805 CDS YP_001724193.1 170019239 6067661 1315122..1315835 1 NC_010468.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1315835 6067661 EcolC_1200 Escherichia coli ATCC 8739 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001724193.1 1315122 D 481805 CDS YP_001724194.1 170019240 6065224 1316003..1316866 1 NC_010468.1 PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: sfv:SFV_2520 hypothetical protein; hypothetical protein 1316866 6065224 EcolC_1201 Escherichia coli ATCC 8739 hypothetical protein YP_001724194.1 1316003 D 481805 CDS YP_001724195.1 170019241 6067451 1316881..1318896 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; protein of unknown function DUF699 ATPase putative; KEGG: ssn:SSON_2555 hypothetical protein; hypothetical protein 1318896 6067451 EcolC_1202 Escherichia coli ATCC 8739 hypothetical protein YP_001724195.1 1316881 D 481805 CDS YP_001724196.1 170019242 6067470 1318970..1319668 1 NC_010468.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 1319668 6067470 EcolC_1203 Escherichia coli ATCC 8739 esterase YpfH YP_001724196.1 1318970 D 481805 CDS YP_001724197.1 170019243 6067112 complement(1319778..1319978) 1 NC_010468.1 KEGG: sdy:SDY_2657 hypothetical protein; hypothetical protein 1319978 6067112 EcolC_1204 Escherichia coli ATCC 8739 hypothetical protein YP_001724197.1 1319778 R 481805 CDS YP_001724198.1 170019244 6067161 complement(1320006..1321133) 1 NC_010468.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1321133 6067161 EcolC_1205 Escherichia coli ATCC 8739 succinyl-diaminopimelate desuccinylase YP_001724198.1 1320006 R 481805 CDS YP_001724199.1 170019245 6067526 complement(1321137..1321493) 1 NC_010468.1 PFAM: arsenate reductase and related; KEGG: sdy:SDY_2655 hypothetical protein; hypothetical protein 1321493 6067526 EcolC_1206 Escherichia coli ATCC 8739 hypothetical protein YP_001724199.1 1321137 R 481805 CDS YP_001724200.1 170019246 6068734 complement(1322032..1325145) 1 NC_010468.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: ssn:SSON_2550 AcrD; aminoglycoside/multidrug efflux system 1325145 6068734 EcolC_1207 Escherichia coli ATCC 8739 aminoglycoside/multidrug efflux system YP_001724200.1 1322032 R 481805 CDS YP_001724201.1 170019247 6066063 complement(1325309..1327009) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sdy:SDY_2653 sensor for nitrate reductase system; nitrate/nitrite sensor protein NarQ 1327009 6066063 EcolC_1208 Escherichia coli ATCC 8739 nitrate/nitrite sensor protein NarQ YP_001724201.1 1325309 R 481805 CDS YP_001724202.1 170019248 6067092 1327215..1329194 1 NC_010468.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 1329194 6067092 EcolC_1209 Escherichia coli ATCC 8739 putative oxidoreductase Fe-S binding subunit YP_001724202.1 1327215 D 481805 CDS YP_001724203.1 170019249 6064352 1329262..1329837 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sbo:SBO_2483 hypothetical protein; NUDIX hydrolase 1329837 6064352 EcolC_1210 Escherichia coli ATCC 8739 NUDIX hydrolase YP_001724203.1 1329262 D 481805 CDS YP_001724204.1 170019250 6067556 1329963..1331006 1 NC_010468.1 PFAM: protein of unknown function DUF1176; KEGG: sbo:SBO_2482 hypothetical protein; hypothetical protein 1331006 6067556 EcolC_1211 Escherichia coli ATCC 8739 hypothetical protein YP_001724204.1 1329963 D 481805 CDS YP_001724205.1 170019251 6065611 complement(1331101..1333104) 1 NC_010468.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1333104 6065611 EcolC_1212 Escherichia coli ATCC 8739 transketolase YP_001724205.1 1331101 R 481805 CDS YP_001724206.1 170019252 6067205 complement(1333124..1334074) 1 NC_010468.1 KEGG: ssn:SSON_2544 transaldolase A; TIGRFAM: transaldolase; PFAM: Transaldolase; transaldolase A 1334074 6067205 EcolC_1213 Escherichia coli ATCC 8739 transaldolase A YP_001724206.1 1333124 R 481805 CDS YP_001724207.1 170019253 6067672 1334363..1336642 1 NC_010468.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 1336642 6067672 EcolC_1214 Escherichia coli ATCC 8739 malic enzyme YP_001724207.1 1334363 D 481805 CDS YP_001724208.1 170019254 6064636 1336935..1337270 1 NC_010468.1 PFAM: microcompartments protein; KEGG: sfv:SFV_2506 hypothetical protein; microcompartments protein 1337270 6064636 EcolC_1215 Escherichia coli ATCC 8739 microcompartments protein YP_001724208.1 1336935 D 481805 CDS YP_001724209.1 170019255 6066266 1337283..1337762 1 NC_010468.1 TIGRFAM: ethanolamine utilization protein, EutP; KEGG: sbo:SBO_2476 hypothetical protein; ethanolamine utilization protein EutP 1337762 6066266 EcolC_1216 Escherichia coli ATCC 8739 ethanolamine utilization protein EutP YP_001724209.1 1337283 D 481805 CDS YP_001724210.1 170019256 6066237 1337737..1338438 1 NC_010468.1 PFAM: protein of unknown function DUF861 cupin_3; Ethanolamine utilisation EutQ family protein; KEGG: ssn:SSON_2540 hypothetical protein; ethanolamine utilisation EutQ family protein 1338438 6066237 EcolC_1217 Escherichia coli ATCC 8739 ethanolamine utilisation EutQ family protein YP_001724210.1 1337737 D 481805 CDS YP_001724211.1 170019257 6065205 1338435..1339244 1 NC_010468.1 PFAM: cobalamin adenosyltransferase; KEGG: sbo:SBO_2474 hypothetical protein; cob(I)yrinic acid a,c-diamide adenosyltransferase 1339244 6065205 EcolC_1218 Escherichia coli ATCC 8739 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001724211.1 1338435 D 481805 CDS YP_001724212.1 170019258 6066023 1339234..1340250 1 NC_010468.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1340250 eutD 6066023 eutD Escherichia coli ATCC 8739 phosphotransacetylase YP_001724212.1 1339234 D 481805 CDS YP_001724213.1 170019259 6067441 1340247..1340582 1 NC_010468.1 PFAM: microcompartments protein; KEGG: sbo:SBO_2472 detox protein; microcompartments protein 1340582 6067441 EcolC_1220 Escherichia coli ATCC 8739 microcompartments protein YP_001724213.1 1340247 D 481805 CDS YP_001724214.1 170019260 6067574 1340689..1340976 1 NC_010468.1 PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: sbo:SBO_2471 detox protein; ethanolamine utilization protein EutN/carboxysome structural protein Ccml 1340976 6067574 EcolC_1221 Escherichia coli ATCC 8739 ethanolamine utilization protein EutN/carboxysome structural protein Ccml YP_001724214.1 1340689 D 481805 CDS YP_001724215.1 170019261 6065287 1340988..1342391 1 NC_010468.1 PFAM: Aldehyde Dehydrogenase_; KEGG: sbo:SBO_2470 ethanolamine utilization; aldehyde dehydrogenase 1342391 6065287 EcolC_1222 Escherichia coli ATCC 8739 aldehyde dehydrogenase YP_001724215.1 1340988 D 481805 CDS YP_001724216.1 170019262 6065821 1342402..1343238 1 NC_010468.1 TIGRFAM: ethanolamine utilization protein EutJ family protein; KEGG: sbo:SBO_2469 ethanolamine utilization; ethanolamine utilization protein EutJ family protein 1343238 6065821 EcolC_1223 Escherichia coli ATCC 8739 ethanolamine utilization protein EutJ family protein YP_001724216.1 1342402 D 481805 CDS YP_001724217.1 170019263 6067373 1343228..1344415 1 NC_010468.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2533 EutG; iron-containing alcohol dehydrogenase 1344415 6067373 EcolC_1224 Escherichia coli ATCC 8739 iron-containing alcohol dehydrogenase YP_001724217.1 1343228 D 481805 CDS YP_001724218.1 170019264 6067264 1344632..1345858 1 NC_010468.1 PFAM: Ethanolamine utilisation protein EutH; KEGG: ssn:SSON_2532 EutH; ethanolamine utilisation protein EutH 1345858 6067264 EcolC_1225 Escherichia coli ATCC 8739 ethanolamine utilisation protein EutH YP_001724218.1 1344632 D 481805 CDS YP_001724219.1 170019265 6066870 1345855..1347258 1 NC_010468.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 1347258 eutA 6066870 eutA Escherichia coli ATCC 8739 reactivating factor for ethanolamine ammonia lyase YP_001724219.1 1345855 D 481805 CDS YP_001724220.1 170019266 6066905 complement(1347387..1347989) 1 NC_010468.1 KEGG: shw:Sputw3181_2459 DNA-binding protein; hypothetical protein 1347989 6066905 EcolC_1227 Escherichia coli ATCC 8739 hypothetical protein YP_001724220.1 1347387 R 481805 CDS YP_001724221.1 170019267 6066573 complement(1348203..1348985) 1 NC_010468.1 hypothetical protein 1348985 6066573 EcolC_1228 Escherichia coli ATCC 8739 hypothetical protein YP_001724221.1 1348203 R 481805 CDS YP_001724222.1 170019268 6064589 complement(1349125..1349601) 1 NC_010468.1 hypothetical protein 1349601 6064589 EcolC_1229 Escherichia coli ATCC 8739 hypothetical protein YP_001724222.1 1349125 R 481805 CDS YP_001724223.1 170019269 6065243 complement(1350122..1352302) 1 NC_010468.1 KEGG: esa:ESA_02313 hypothetical protein; hypothetical protein 1352302 6065243 EcolC_1230 Escherichia coli ATCC 8739 hypothetical protein YP_001724223.1 1350122 R 481805 CDS YP_001724224.1 170019270 6065613 complement(1352591..1352821) 1 NC_010468.1 KEGG: sfv:SFV_2497 hypothetical protein; hypothetical protein 1352821 6065613 EcolC_1231 Escherichia coli ATCC 8739 hypothetical protein YP_001724224.1 1352591 R 481805 CDS YP_001724225.1 170019271 6067625 complement(1352860..1353189) 1 NC_010468.1 KEGG: sfx:S2646 hypothetical protein; hypothetical protein 1353189 6067625 EcolC_1232 Escherichia coli ATCC 8739 hypothetical protein YP_001724225.1 1352860 R 481805 CDS YP_001724226.1 170019272 6067605 complement(1353286..1353828) 1 NC_010468.1 KEGG: sfv:SFV_2496 hypothetical protein; hypothetical protein 1353828 6067605 EcolC_1233 Escherichia coli ATCC 8739 hypothetical protein YP_001724226.1 1353286 R 481805 CDS YP_001724227.1 170019273 6067495 complement(1353846..1354109) 1 NC_010468.1 KEGG: sfv:SFV_2495 hypothetical protein; hypothetical protein 1354109 6067495 EcolC_1234 Escherichia coli ATCC 8739 hypothetical protein YP_001724227.1 1353846 R 481805 CDS YP_001724228.1 170019274 6067474 complement(1354127..1354522) 1 NC_010468.1 PFAM: HNH endonuclease; KEGG: sfx:S2643 hypothetical protein; HNH endonuclease 1354522 6067474 EcolC_1235 Escherichia coli ATCC 8739 HNH endonuclease YP_001724228.1 1354127 R 481805 CDS YP_001724229.1 170019275 6067420 1355181..1355510 1 NC_010468.1 hypothetical protein 1355510 6067420 EcolC_1236 Escherichia coli ATCC 8739 hypothetical protein YP_001724229.1 1355181 D 481805 CDS YP_001724230.1 170019276 6067412 complement(1356303..1357508) 1 NC_010468.1 PFAM: integrase family protein; KEGG: ypp:YPDSF_3775 phage integrase; integrase family protein 1357508 6067412 EcolC_1237 Escherichia coli ATCC 8739 integrase family protein YP_001724230.1 1356303 R 481805 CDS YP_001724231.1 170019277 6067354 1357697..1359058 1 NC_010468.1 PFAM: Ethanolamine ammonia lyase large subunit; KEGG: stm:STM2458 ethanolamine ammonia-lyase, heavy chain; ethanolamine ammonia lyase large subunit 1359058 6067354 EcolC_1238 Escherichia coli ATCC 8739 ethanolamine ammonia lyase large subunit YP_001724231.1 1357697 D 481805 CDS YP_001724232.1 170019278 6067290 1359079..1359966 1 NC_010468.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 1359966 6067290 EcolC_1239 Escherichia coli ATCC 8739 ethanolamine ammonia-lyase small subunit YP_001724232.1 1359079 D 481805 CDS YP_001724233.1 170019279 6067147 1359976..1360635 1 NC_010468.1 PFAM: microcompartments protein; KEGG: sbo:SBO_2464 hypothetical protein; microcompartments protein 1360635 6067147 EcolC_1240 Escherichia coli ATCC 8739 microcompartments protein YP_001724233.1 1359976 D 481805 CDS YP_001724234.1 170019280 6064841 1360648..1361148 1 NC_010468.1 PFAM: microcompartments protein; KEGG: sdy:SDY_2636 hypothetical protein; microcompartments protein 1361148 6064841 EcolC_1241 Escherichia coli ATCC 8739 microcompartments protein YP_001724234.1 1360648 D 481805 CDS YP_001724235.1 170019281 6066986 1361194..1362246 1 NC_010468.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 1362246 6066986 EcolC_1242 Escherichia coli ATCC 8739 transcriptional regulator EutR YP_001724235.1 1361194 D 481805 CDS YP_001724236.1 170019282 6066827 complement(1362252..1363151) 1 NC_010468.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1363151 6066827 EcolC_1243 Escherichia coli ATCC 8739 coproporphyrinogen III oxidase YP_001724236.1 1362252 R 481805 CDS YP_001724237.1 170019283 6066639 complement(1363155..1364024) 1 NC_010468.1 PFAM: cell wall hydrolase/autolysin; KEGG: sbo:SBO_2460 N-acetylmuramoyl-L-alanine amidase I; N-acetylmuramoyl-l-alanine amidase I 1364024 6066639 EcolC_1244 Escherichia coli ATCC 8739 N-acetylmuramoyl-l-alanine amidase I YP_001724237.1 1363155 R 481805 CDS YP_001724238.1 170019284 6066338 1364238..1364663 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_2632 hypothetical protein; putative acetyltransferase 1364663 6066338 EcolC_1245 Escherichia coli ATCC 8739 putative acetyltransferase YP_001724238.1 1364238 D 481805 CDS YP_001724239.1 170019285 6066212 1364650..1365099 1 NC_010468.1 KEGG: ssn:SSON_2522 hypothetical protein; hypothetical protein 1365099 6066212 EcolC_1246 Escherichia coli ATCC 8739 hypothetical protein YP_001724239.1 1364650 D 481805 CDS YP_001724240.1 170019286 6066361 1365306..1365881 1 NC_010468.1 PFAM: protein of unknown function DUF1131; KEGG: ssn:SSON_2521 hypothetical protein; hypothetical protein 1365881 6066361 EcolC_1247 Escherichia coli ATCC 8739 hypothetical protein YP_001724240.1 1365306 D 481805 CDS YP_001724241.1 170019287 6066123 1365977..1366876 1 NC_010468.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbo:SBO_2456 hypothetical protein; Dyp-type peroxidase family protein 1366876 6066123 EcolC_1248 Escherichia coli ATCC 8739 Dyp-type peroxidase family protein YP_001724241.1 1365977 D 481805 CDS YP_001724242.1 170019288 6066079 complement(1366934..1368238) 1 NC_010468.1 PFAM: beta-lactamase; KEGG: ssn:SSON_2519 putative beta-lactamase; hypothetical protein 1368238 6066079 EcolC_1249 Escherichia coli ATCC 8739 hypothetical protein YP_001724242.1 1366934 R 481805 CDS YP_001724243.1 170019289 6065864 complement(1368243..1369667) 1 NC_010468.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 1369667 murP 6065864 murP Escherichia coli ATCC 8739 PTS system N-acetylmuramic acid transporter subunit IIBC YP_001724243.1 1368243 R 481805 CDS YP_001724244.1 170019290 6065765 complement(1369671..1370567) 1 NC_010468.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1370567 murQ 6065765 murQ Escherichia coli ATCC 8739 N-acetylmuramic acid 6-phosphate etherase YP_001724244.1 1369671 R 481805 CDS YP_001724245.1 170019291 6065586 1370731..1371588 1 NC_010468.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ssn:SSON_2516 hypothetical protein; RpiR family transcriptional regulator 1371588 6065586 EcolC_1252 Escherichia coli ATCC 8739 RpiR family transcriptional regulator YP_001724245.1 1370731 D 481805 CDS YP_001724246.1 170019292 6065528 1371717..1372508 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbo:SBO_2451 putative oxidoreductase; short chain dehydrogenase 1372508 6065528 EcolC_1253 Escherichia coli ATCC 8739 short chain dehydrogenase YP_001724246.1 1371717 D 481805 CDS YP_001724247.1 170019293 6065578 1372666..1373682 1 NC_010468.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_2450 thiosulfate binding protein; thiosulfate transporter subunit 1373682 6065578 EcolC_1254 Escherichia coli ATCC 8739 thiosulfate transporter subunit YP_001724247.1 1372666 D 481805 CDS YP_001724248.1 170019294 6065476 1373682..1374515 1 NC_010468.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_2449 sulfate, thiosulfate transport system permease T protein; sulfate/thiosulfate transporter subunit 1374515 6065476 EcolC_1255 Escherichia coli ATCC 8739 sulfate/thiosulfate transporter subunit YP_001724248.1 1373682 D 481805 CDS YP_001724249.1 170019295 6065433 1374515..1375390 1 NC_010468.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease 1375390 cysW 6065433 cysW Escherichia coli ATCC 8739 sulfate/thiosulfate transporter permease YP_001724249.1 1374515 D 481805 CDS YP_001724250.1 170019296 6065215 1375380..1376477 1 NC_010468.1 KEGG: sbo:SBO_2447 ATP-binding component of sulfate permease A protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; sulfate/thiosulfate transporter subunit 1376477 6065215 EcolC_1257 Escherichia coli ATCC 8739 sulfate/thiosulfate transporter subunit YP_001724250.1 1375380 D 481805 CDS YP_001724251.1 170019297 6065240 1376611..1377522 1 NC_010468.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 1377522 cysM 6065240 cysM Escherichia coli ATCC 8739 cysteine synthase B YP_001724251.1 1376611 D 481805 CDS YP_001724252.1 170019298 6065109 complement(1377525..1377893) 1 NC_010468.1 KEGG: sbo:SBO_2445 hypothetical protein; hypothetical protein 1377893 6065109 EcolC_1259 Escherichia coli ATCC 8739 hypothetical protein YP_001724252.1 1377525 R 481805 CDS YP_001724253.1 170019299 6065064 1377998..1378849 1 NC_010468.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 1378849 pdxK 6065064 pdxK Escherichia coli ATCC 8739 pyridoxal kinase YP_001724253.1 1377998 D 481805 CDS YP_001724254.1 170019300 6064952 complement(1378892..1379401) 1 NC_010468.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 1379401 6064952 EcolC_1261 Escherichia coli ATCC 8739 PTS system glucose-specific transporter YP_001724254.1 1378892 R 481805 CDS YP_001724255.1 170019301 6064788 complement(1379442..1381169) 1 NC_010468.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 1381169 6064788 EcolC_1262 Escherichia coli ATCC 8739 phosphoenolpyruvate-protein phosphotransferase YP_001724255.1 1379442 R 481805 CDS YP_001724256.1 170019302 6064813 complement(1381214..1381471) 1 NC_010468.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: stm:STM2431 PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 1381471 6064813 EcolC_1263 Escherichia coli ATCC 8739 PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_001724256.1 1381214 R 481805 CDS YP_001724257.1 170019303 6064830 complement(1381855..1382826) 1 NC_010468.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 1382826 6064830 EcolC_1264 Escherichia coli ATCC 8739 cysteine synthase A YP_001724257.1 1381855 R 481805 CDS YP_001724258.1 170019304 6064744 complement(1383011..1383772) 1 NC_010468.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 1383772 6064744 EcolC_1265 Escherichia coli ATCC 8739 putative sulfate transport protein CysZ YP_001724258.1 1383011 R 481805 CDS YP_001724259.1 170019305 6064705 1384002..1384988 1 NC_010468.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 1384988 6064705 EcolC_1266 Escherichia coli ATCC 8739 cell division protein ZipA YP_001724259.1 1384002 D 481805 CDS YP_001724260.1 170019306 6064591 1385059..1387074 1 NC_010468.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1387074 ligA 6064591 ligA Escherichia coli ATCC 8739 NAD-dependent DNA ligase LigA YP_001724260.1 1385059 D 481805 CDS YP_001724261.1 170019307 6064643 1387076..1387294 1 NC_010468.1 KEGG: sdy:SDY_2607 Z3676 gene product; hypothetical protein 1387294 6064643 EcolC_1268 Escherichia coli ATCC 8739 hypothetical protein YP_001724261.1 1387076 D 481805 CDS YP_001724262.1 170019308 6067064 complement(1387291..1388289) 1 NC_010468.1 PFAM: Bile acid:sodium symporter; KEGG: ssn:SSON_2498 putative cytochrome oxidase; bile acid:sodium symporter 1388289 6067064 EcolC_1269 Escherichia coli ATCC 8739 bile acid:sodium symporter YP_001724262.1 1387291 R 481805 CDS YP_001724263.1 170019309 6067252 1388379..1389305 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2432 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 1389305 6067252 EcolC_1270 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001724263.1 1388379 D 481805 CDS YP_001724264.1 170019310 6066558 complement(1389296..1389637) 1 NC_010468.1 KEGG: sfv:SFV_2459 hypothetical protein; hypothetical protein 1389637 6066558 EcolC_1271 Escherichia coli ATCC 8739 hypothetical protein YP_001724264.1 1389296 R 481805 CDS YP_001724265.1 170019311 6064541 1390413..1391828 1 NC_010468.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1391828 gltX 6064541 gltX Escherichia coli ATCC 8739 glutamyl-tRNA synthetase YP_001724265.1 1390413 D 481805 CDS YP_001724266.1 170019312 6064486 complement(1391880..1392272) 1 NC_010468.1 PFAM: protein of unknown function DUF1323; KEGG: sbo:SBO_2425 hypothetical protein; hypothetical protein 1392272 6064486 EcolC_1273 Escherichia coli ATCC 8739 hypothetical protein YP_001724266.1 1391880 R 481805 CDS YP_001724267.1 170019313 6064478 complement(1392274..1392633) 1 NC_010468.1 PFAM: protein of unknown function DUF1323; KEGG: sdy:SDY_2596 hypothetical protein; hypothetical protein 1392633 6064478 EcolC_1274 Escherichia coli ATCC 8739 hypothetical protein YP_001724267.1 1392274 R 481805 CDS YP_001724268.1 170019314 6068173 1393253..1395442 1 NC_010468.1 PFAM: GGDEF domain containing protein; EAL domain protein; MASE1 domain protein; KEGG: sbo:SBO_2421 hypothetical protein; diguanylate cyclase/phosphodiesterase 1395442 6068173 EcolC_1275 Escherichia coli ATCC 8739 diguanylate cyclase/phosphodiesterase YP_001724268.1 1393253 D 481805 CDS YP_001724269.1 170019315 6068717 1395526..1396638 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein 1396638 6068717 EcolC_1276 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001724269.1 1395526 D 481805 CDS YP_001724270.1 170019316 6068405 complement(1396841..1398043) 1 NC_010468.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sdy:SDY_2593 permease of transport system for 3 nucleosides; nucleoside transporter 1398043 6068405 EcolC_1277 Escherichia coli ATCC 8739 nucleoside transporter YP_001724270.1 1396841 R 481805 CDS YP_001724271.1 170019317 6065937 1398379..1399617 1 NC_010468.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: sbo:SBO_2417 putative transport system permease; manganese transport protein MntH 1399617 6065937 EcolC_1278 Escherichia coli ATCC 8739 manganese transport protein MntH YP_001724271.1 1398379 D 481805 CDS YP_001724272.1 170019318 6068739 complement(1399758..1400084) 1 NC_010468.1 KEGG: sbo:SBO_2416 hypothetical protein; hypothetical protein 1400084 6068739 EcolC_1279 Escherichia coli ATCC 8739 hypothetical protein YP_001724272.1 1399758 R 481805 CDS YP_001724273.1 170019319 6068727 complement(1400199..1401455) 1 NC_010468.1 PFAM: Chloride channel core; KEGG: sfv:SFV_2447 hypothetical protein; hypothetical protein 1401455 6068727 EcolC_1280 Escherichia coli ATCC 8739 hypothetical protein YP_001724273.1 1400199 R 481805 CDS YP_001724274.1 170019320 6068725 1401659..1402624 1 NC_010468.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1402624 glk 6068725 glk Escherichia coli ATCC 8739 glucokinase YP_001724274.1 1401659 D 481805 CDS YP_001724275.1 170019321 6068713 1402843..1403169 1 NC_010468.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; KEGG: sbo:SBO_2413 putative PTS system enzyme IIB component; PTS system fructose-specific transporter subunit IIB 1403169 6068713 EcolC_1282 Escherichia coli ATCC 8739 PTS system fructose-specific transporter subunit IIB YP_001724275.1 1402843 D 481805 CDS YP_001724276.1 170019322 6068709 1403191..1404438 1 NC_010468.1 TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: ssn:SSON_2478 putative transport protein; PTS system fructose subfamily transporter subunit IIC 1404438 6068709 EcolC_1283 Escherichia coli ATCC 8739 PTS system fructose subfamily transporter subunit IIC YP_001724276.1 1403191 D 481805 CDS YP_001724277.1 170019323 6068699 1404453..1405538 1 NC_010468.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 1405538 6068699 EcolC_1284 Escherichia coli ATCC 8739 aminopeptidase YP_001724277.1 1404453 D 481805 CDS YP_001724278.1 170019324 6068696 1405538..1406575 1 NC_010468.1 metalloprotein; exoaminopeptidase 1406575 6068696 EcolC_1285 Escherichia coli ATCC 8739 exoaminopeptidase YP_001724278.1 1405538 D 481805 CDS YP_001724279.1 170019325 6068688 1406600..1409095 1 NC_010468.1 TIGRFAM: PTS system, fructose subfamily, IIA subunit; phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: sfv:SFV_2441 putative PTS system enzyme IIA component, enzyme I; phosphoenolpyruvate-protein phosphotransferase 1409095 6068688 EcolC_1286 Escherichia coli ATCC 8739 phosphoenolpyruvate-protein phosphotransferase YP_001724279.1 1406600 D 481805 CDS YP_001724280.1 170019326 6068685 complement(1409098..1409955) 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_2474 putative AraC-type regulatory protein; AraC family transcriptional regulator 1409955 6068685 EcolC_1287 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001724280.1 1409098 R 481805 CDS YP_001724281.1 170019327 6068680 complement(1409968..1410702) 1 NC_010468.1 PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: sbo:SBO_2407 putative 2-component transcriptional regulator; LytTR family two component transcriptional regulator 1410702 6068680 EcolC_1288 Escherichia coli ATCC 8739 LytTR family two component transcriptional regulator YP_001724281.1 1409968 R 481805 CDS YP_001724282.1 170019328 6068671 complement(1410717..1412396) 1 NC_010468.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: sbo:SBO_2406 putative sensor protein; signal transduction histidine kinase LytS 1412396 6068671 EcolC_1289 Escherichia coli ATCC 8739 signal transduction histidine kinase LytS YP_001724282.1 1410717 R 481805 CDS YP_001724283.1 170019329 6068665 1412791..1414029 1 NC_010468.1 PFAM: aminotransferase class I and II; KEGG: ssn:SSON_2470 putative aminotransferase; aminotransferase 1414029 6068665 EcolC_1290 Escherichia coli ATCC 8739 aminotransferase YP_001724283.1 1412791 D 481805 CDS YP_001724284.1 170019330 6068662 complement(1414521..1415441) 1 NC_010468.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 1415441 6068662 EcolC_1291 Escherichia coli ATCC 8739 lipid A biosynthesis palmitoleoyl acyltransferase YP_001724284.1 1414521 R 481805 CDS YP_001724285.1 170019331 6068656 1415794..1416036 1 NC_010468.1 KEGG: sdy:SDY_2575 hypothetical protein; hypothetical protein 1416036 6068656 EcolC_1292 Escherichia coli ATCC 8739 hypothetical protein YP_001724285.1 1415794 D 481805 CDS YP_001724286.1 170019332 6068644 complement(1416113..1416388) 1 NC_010468.1 KEGG: ssn:SSON_2467 hypothetical protein; hypothetical protein 1416388 6068644 EcolC_1293 Escherichia coli ATCC 8739 hypothetical protein YP_001724286.1 1416113 R 481805 CDS YP_001724287.1 170019333 6068638 1416684..1417316 1 NC_010468.1 KEGG: sdy:SDY_2573 hypothetical protein; hypothetical protein 1417316 6068638 EcolC_1294 Escherichia coli ATCC 8739 hypothetical protein YP_001724287.1 1416684 D 481805 CDS YP_001724288.1 170019334 6068617 1417829..1419079 1 NC_010468.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 1419079 6068617 EcolC_1295 Escherichia coli ATCC 8739 formyl-coenzyme A transferase YP_001724288.1 1417829 D 481805 CDS YP_001724289.1 170019335 6068609 1419133..1420827 1 NC_010468.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase 1420827 6068609 EcolC_1296 Escherichia coli ATCC 8739 putative oxalyl-CoA decarboxylase YP_001724289.1 1419133 D 481805 CDS YP_001724290.1 170019336 6068595 1420897..1421841 1 NC_010468.1 member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV 1421841 6068595 EcolC_1297 Escherichia coli ATCC 8739 putative transporter YfdV YP_001724290.1 1420897 D 481805 CDS YP_001724291.1 170019337 6068585 1421915..1423060 1 NC_010468.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sbo:SBO_2397 putative enzyme; hypothetical protein 1423060 6068585 EcolC_1298 Escherichia coli ATCC 8739 hypothetical protein YP_001724291.1 1421915 D 481805 CDS YP_001724292.1 170019338 6068577 complement(1423116..1426709) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 3; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: sfv:SFV_2429 putative sensor for regulator EvgA; hybrid sensory histidine kinase in two-component regulatory system with EvgA 1426709 6068577 EcolC_1299 Escherichia coli ATCC 8739 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_001724292.1 1423116 R 481805 CDS YP_001724293.1 170019339 6068574 complement(1426714..1427328) 1 NC_010468.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 1427328 6068574 EcolC_1300 Escherichia coli ATCC 8739 DNA-binding transcriptional activator EvgA YP_001724293.1 1426714 R 481805 CDS YP_001724294.1 170019340 6068571 1427744..1428907 1 NC_010468.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_2394 multidrug resistance protein K; efflux pump membrane protein 1428907 6068571 EcolC_1301 Escherichia coli ATCC 8739 efflux pump membrane protein YP_001724294.1 1427744 D 481805 CDS YP_001724295.1 170019341 6068565 1428907..1430445 1 NC_010468.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2393 multidrug resistance protein Y; EmrB/QacA family drug resistance transporter 1430445 6068565 EcolC_1302 Escherichia coli ATCC 8739 EmrB/QacA family drug resistance transporter YP_001724295.1 1428907 D 481805 CDS YP_001724296.1 170019342 6068555 complement(1430553..1431881) 1 NC_010468.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 1431881 6068555 EcolC_1303 Escherichia coli ATCC 8739 D-serine dehydratase YP_001724296.1 1430553 R 481805 CDS YP_001724297.1 170019343 6068551 complement(1431899..1433236) 1 NC_010468.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 1433236 6068551 EcolC_1304 Escherichia coli ATCC 8739 permease DsdX YP_001724297.1 1431899 R 481805 CDS YP_001724298.1 170019344 6068547 1433454..1434389 1 NC_010468.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 1434389 6068547 EcolC_1305 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator DsdC YP_001724298.1 1433454 D 481805 CDS YP_001724299.1 170019345 6068535 complement(1434635..1435567) 1 NC_010468.1 KEGG: sdy:SDY_2551 putative transport; putative transport 1435567 6068535 EcolC_1306 Escherichia coli ATCC 8739 putative transport YP_001724299.1 1434635 R 481805 CDS YP_001724300.1 170019346 6068530 1435861..1436616 1 NC_010468.1 PFAM: VacJ family lipoprotein; KEGG: sdy:SDY_2550 lipoprotein precursor; VacJ family lipoprotein 1436616 6068530 EcolC_1307 Escherichia coli ATCC 8739 VacJ family lipoprotein YP_001724300.1 1435861 D 481805 CDS YP_001724301.1 170019347 6068528 complement(1436798..1437856) 1 NC_010468.1 KEGG: sfx:S2558 hypothetical protein; hypothetical protein 1437856 6068528 EcolC_1308 Escherichia coli ATCC 8739 hypothetical protein YP_001724301.1 1436798 R 481805 CDS YP_001724302.1 170019348 6068526 complement(1438223..1439563) 1 NC_010468.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: ssn:SSON_2400 transport of long-chain fatty acids; sensitivity to phage T2; long-chain fatty acid outer membrane transporter 1439563 6068526 EcolC_1309 Escherichia coli ATCC 8739 long-chain fatty acid outer membrane transporter YP_001724302.1 1438223 R 481805 CDS YP_001724303.1 170019349 6068505 1439935..1440219 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2381 hypothetical protein; hypothetical protein 1440219 6068505 EcolC_1310 Escherichia coli ATCC 8739 hypothetical protein YP_001724303.1 1439935 D 481805 CDS YP_001724304.1 170019350 6068500 1440400..1441710 1 NC_010468.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 1441710 fadI 6068500 fadI Escherichia coli ATCC 8739 3-ketoacyl-CoA thiolase YP_001724304.1 1440400 D 481805 CDS YP_001724305.1 170019351 6068474 1441710..1443854 1 NC_010468.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 1443854 fadJ 6068474 fadJ Escherichia coli ATCC 8739 multifunctional fatty acid oxidation complex subunit alpha YP_001724305.1 1441710 D 481805 CDS YP_001724306.1 170019352 6068465 1444057..1444542 1 NC_010468.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: sbo:SBO_2378 hypothetical protein; phosphohistidine phosphatase 1444542 6068465 EcolC_1313 Escherichia coli ATCC 8739 phosphohistidine phosphatase YP_001724306.1 1444057 D 481805 CDS YP_001724307.1 170019353 6068458 1445226..1445789 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: sfx:S2550 putative fimbrial-like protein; fimbrial protein 1445789 6068458 EcolC_1314 Escherichia coli ATCC 8739 fimbrial protein YP_001724307.1 1445226 D 481805 CDS YP_001724308.1 170019354 6068451 1445872..1448517 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sbo:SBO_2376 PapC-like porin protein; fimbrial biogenesis outer membrane usher protein 1448517 6068451 EcolC_1315 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001724308.1 1445872 D 481805 CDS YP_001724309.1 170019355 6068441 1448537..1449289 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: sbo:SBO_2375 putative chaperone; pili assembly chaperone 1449289 6068441 EcolC_1316 Escherichia coli ATCC 8739 pili assembly chaperone YP_001724309.1 1448537 D 481805 CDS YP_001724310.1 170019356 6068436 1449305..1449814 1 NC_010468.1 KEGG: sbo:SBO_2374 putative fimbrial protein; putative fimbrial protein 1449814 6068436 EcolC_1317 Escherichia coli ATCC 8739 putative fimbrial protein YP_001724310.1 1449305 D 481805 CDS YP_001724311.1 170019357 6068423 1449811..1450299 1 NC_010468.1 KEGG: sbo:SBO_2373 hypothetical protein; hypothetical protein 1450299 6068423 EcolC_1318 Escherichia coli ATCC 8739 hypothetical protein YP_001724311.1 1449811 D 481805 CDS YP_001724312.1 170019358 6068419 1450296..1450835 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: sbo:SBO_2372 putative fimbrial-like protein; fimbrial protein 1450835 6068419 EcolC_1319 Escherichia coli ATCC 8739 fimbrial protein YP_001724312.1 1450296 D 481805 CDS YP_001724313.1 170019359 6068412 1450837..1451694 1 NC_010468.1 KEGG: sbo:SBO_2369 hypothetical protein; hypothetical protein 1451694 6068412 EcolC_1320 Escherichia coli ATCC 8739 hypothetical protein YP_001724313.1 1450837 D 481805 CDS YP_001724314.1 170019360 6068393 complement(1451766..1452317) 1 NC_010468.1 PFAM: Smr protein/MutS2; KEGG: sbo:SBO_2367 hypothetical protein; hypothetical protein 1452317 6068393 EcolC_1321 Escherichia coli ATCC 8739 hypothetical protein YP_001724314.1 1451766 R 481805 CDS YP_001724315.1 170019361 6068389 1452483..1453415 1 NC_010468.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1453415 6068389 EcolC_1322 Escherichia coli ATCC 8739 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001724315.1 1452483 D 481805 CDS YP_001724316.1 170019362 6068370 1453450..1454535 1 NC_010468.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1454535 6068370 EcolC_1323 Escherichia coli ATCC 8739 chorismate synthase YP_001724316.1 1453450 D 481805 CDS YP_001724317.1 170019363 6068353 1454539..1455363 1 NC_010468.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1455363 mepA 6068353 mepA Escherichia coli ATCC 8739 penicillin-insensitive murein endopeptidase YP_001724317.1 1454539 D 481805 CDS YP_001724318.1 170019364 6068335 1455363..1456172 1 NC_010468.1 PFAM: protein of unknown function DUF81; KEGG: ssn:SSON_2385 putative structural protein; hypothetical protein 1456172 6068335 EcolC_1325 Escherichia coli ATCC 8739 hypothetical protein YP_001724318.1 1455363 D 481805 CDS YP_001724319.1 170019365 6068330 1456172..1456720 1 NC_010468.1 PFAM: protein of unknown function DUF462; KEGG: sfx:S2537 putative transporting ATPase; hypothetical protein 1456720 6068330 EcolC_1326 Escherichia coli ATCC 8739 hypothetical protein YP_001724319.1 1456172 D 481805 CDS YP_001724320.1 170019366 6068324 1456754..1457032 1 NC_010468.1 PFAM: YfcL protein; KEGG: sdy:SDY_2524 hypothetical protein; hypothetical protein 1457032 6068324 EcolC_1327 Escherichia coli ATCC 8739 hypothetical protein YP_001724320.1 1456754 D 481805 CDS YP_001724321.1 170019367 6068320 complement(1457153..1459159) 1 NC_010468.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 1459159 mnmC 6068320 mnmC Escherichia coli ATCC 8739 5-methylaminomethyl-2-thiouridine methyltransferase YP_001724321.1 1457153 R 481805 CDS YP_001724322.1 170019368 6068309 1459318..1460538 1 NC_010468.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1460538 6068309 EcolC_1329 Escherichia coli ATCC 8739 3-oxoacyl-ACP synthase YP_001724322.1 1459318 D 481805 CDS YP_001724323.1 170019369 6068296 1460803..1461981 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2380 putative transport protein; hypothetical protein 1461981 6068296 EcolC_1330 Escherichia coli ATCC 8739 hypothetical protein YP_001724323.1 1460803 D 481805 CDS YP_001724324.1 170019370 6068284 complement(1461978..1462973) 1 NC_010468.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 1462973 flk 6068284 flk Escherichia coli ATCC 8739 flagella biosynthesis regulator YP_001724324.1 1461978 R 481805 CDS YP_001724325.1 170019371 6068275 1463072..1464208 1 NC_010468.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_2378 erythronate-4-phosphate dehyrogenase; D-isomer specific 2-hydroxyacid dehydrogenase catalytic subunit 1464208 6068275 EcolC_1332 Escherichia coli ATCC 8739 D-isomer specific 2-hydroxyacid dehydrogenase catalytic subunit YP_001724325.1 1463072 D 481805 CDS YP_001724326.1 170019372 6068267 1464274..1465287 1 NC_010468.1 PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: sdy:SDY_2518 putative PTS system enzyme II A component; putative semialdehyde dehydrogenase 1465287 6068267 EcolC_1333 Escherichia coli ATCC 8739 putative semialdehyde dehydrogenase YP_001724326.1 1464274 D 481805 CDS YP_001724327.1 170019373 6068265 1465287..1466099 1 NC_010468.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1466099 truA 6068265 truA Escherichia coli ATCC 8739 tRNA pseudouridine synthase A YP_001724327.1 1465287 D 481805 CDS YP_001724328.1 170019374 6068247 1466182..1466841 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_2386 hypothetical protein; hypothetical protein 1466841 6068247 EcolC_1335 Escherichia coli ATCC 8739 hypothetical protein YP_001724328.1 1466182 D 481805 CDS YP_001724329.1 170019375 6068239 1466997..1467911 1 NC_010468.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1467911 6068239 EcolC_1336 Escherichia coli ATCC 8739 acetyl-CoA carboxylase subunit beta YP_001724329.1 1466997 D 481805 CDS YP_001724330.1 170019376 6068235 1467981..1469249 1 NC_010468.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_2352 dihydrofolate:folylpolyglutamate synthetase; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 1469249 6068235 EcolC_1337 Escherichia coli ATCC 8739 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_001724330.1 1467981 D 481805 CDS YP_001724331.1 170019377 6068224 1469239..1469901 1 NC_010468.1 PFAM: Sporulation domain protein; KEGG: sbo:SBO_2351 putative lipoprotein; hypothetical protein 1469901 6068224 EcolC_1338 Escherichia coli ATCC 8739 hypothetical protein YP_001724331.1 1469239 D 481805 CDS YP_001724332.1 170019378 6068222 1470160..1470648 1 NC_010468.1 membrane protein required for colicin V production; colicin V production protein 1470648 6068222 EcolC_1339 Escherichia coli ATCC 8739 colicin V production protein YP_001724332.1 1470160 D 481805 CDS YP_001724333.1 170019379 6068218 1470685..1472202 1 NC_010468.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1472202 6068218 EcolC_1340 Escherichia coli ATCC 8739 amidophosphoribosyltransferase YP_001724333.1 1470685 D 481805 CDS YP_001724334.1 170019380 6068214 1472297..1472866 1 NC_010468.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1472866 6068214 EcolC_1341 Escherichia coli ATCC 8739 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001724334.1 1472297 D 481805 CDS YP_001724335.1 170019381 6068211 1473132..1473914 1 NC_010468.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: ssn:SSON_2368 lysine-, arginine-, ornithine-binding periplasmic protein; cationic amino acid ABC transporter periplasmic binding protein 1473914 6068211 EcolC_1342 Escherichia coli ATCC 8739 cationic amino acid ABC transporter periplasmic binding protein YP_001724335.1 1473132 D 481805 CDS YP_001724336.1 170019382 6068205 1474135..1474917 1 NC_010468.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: sbo:SBO_2346 histidine-binding periplasmic protein of high-affinity histidine transport system; cationic amino acid ABC transporter periplasmic binding protein 1474917 6068205 EcolC_1343 Escherichia coli ATCC 8739 cationic amino acid ABC transporter periplasmic binding protein YP_001724336.1 1474135 D 481805 CDS YP_001724337.1 170019383 6068202 1475007..1475693 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_2507 histidine transport system permease protein; polar amino acid ABC transporter inner membrane protein 1475693 6068202 EcolC_1344 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001724337.1 1475007 D 481805 CDS YP_001724338.1 170019384 6068200 1475690..1476406 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_2506 histidine transport, membrane protein M; polar amino acid ABC transporter inner membrane protein 1476406 6068200 EcolC_1345 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001724338.1 1475690 D 481805 CDS YP_001724339.1 170019385 6068196 1476414..1477187 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_2364 ATP-binding component of histidine transport; histidine/lysine/arginine/ornithine transporter subunit 1477187 6068196 EcolC_1346 Escherichia coli ATCC 8739 histidine/lysine/arginine/ornithine transporter subunit YP_001724339.1 1476414 D 481805 CDS YP_001724340.1 170019386 6068192 1477384..1478274 1 NC_010468.1 PFAM: putative transposase YhgA family protein; KEGG: sfv:SFV_2372 hypothetical protein; putative transposase YhgA family protein 1478274 6068192 EcolC_1347 Escherichia coli ATCC 8739 putative transposase YhgA family protein YP_001724340.1 1477384 D 481805 CDS YP_001724341.1 170019387 6068190 complement(1478322..1479215) 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; domain of unknown function DUF1731; KEGG: sbo:SBO_2339 putative sugar nucleotide epimerase; hypothetical protein 1479215 6068190 EcolC_1348 Escherichia coli ATCC 8739 hypothetical protein YP_001724341.1 1478322 R 481805 CDS YP_001724342.1 170019388 6068186 complement(1479236..1479598) 1 NC_010468.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 1479598 folX 6068186 folX Escherichia coli ATCC 8739 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_001724342.1 1479236 R 481805 CDS YP_001724343.1 170019389 6068184 complement(1479655..1480302) 1 NC_010468.1 PFAM: Glutathione S-transferase domain; KEGG: ssn:SSON_2359 putative S-transferase; glutathione S-transferase 1480302 6068184 EcolC_1350 Escherichia coli ATCC 8739 glutathione S-transferase YP_001724343.1 1479655 R 481805 CDS YP_001724344.1 170019390 6068180 1480438..1481082 1 NC_010468.1 PFAM: Glutathione S-transferase domain; KEGG: sfv:SFV_2368 hypothetical protein; glutathione S-transferase domain-containing protein 1481082 6068180 EcolC_1351 Escherichia coli ATCC 8739 glutathione S-transferase domain-containing protein YP_001724344.1 1480438 D 481805 CDS YP_001724345.1 170019391 6068178 1481138..1481689 1 NC_010468.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: sbo:SBO_2335 hypothetical protein; phosphodiesterase 1481689 6068178 EcolC_1352 Escherichia coli ATCC 8739 phosphodiesterase YP_001724345.1 1481138 D 481805 CDS YP_001724346.1 170019392 6068176 1481747..1482289 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sbo:SBO_2334 putative regulator; NUDIX hydrolase 1482289 6068176 EcolC_1353 Escherichia coli ATCC 8739 NUDIX hydrolase YP_001724346.1 1481747 D 481805 CDS YP_001724347.1 170019393 6068172 complement(1482322..1483800) 1 NC_010468.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: ssn:SSON_2355 putative S-transferase; hypothetical protein 1483800 6068172 EcolC_1354 Escherichia coli ATCC 8739 hypothetical protein YP_001724347.1 1482322 R 481805 CDS YP_001724348.1 170019394 6068169 complement(1484032..1486176) 1 NC_010468.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1486176 6068169 EcolC_1355 Escherichia coli ATCC 8739 phosphate acetyltransferase YP_001724348.1 1484032 R 481805 CDS YP_001724349.1 170019395 6068166 complement(1486251..1487453) 1 NC_010468.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1487453 6068166 EcolC_1356 Escherichia coli ATCC 8739 acetate kinase YP_001724349.1 1486251 R 481805 CDS YP_001724350.1 170019396 6068164 1487792..1488247 1 NC_010468.1 PFAM: protein of unknown function DUF412; KEGG: sdy:SDY_2491 hypothetical protein; hypothetical protein 1488247 6068164 EcolC_1357 Escherichia coli ATCC 8739 hypothetical protein YP_001724350.1 1487792 D 481805 CDS YP_001724351.1 170019397 6068162 1488330..1488824 1 NC_010468.1 PFAM: YfbU family protein; KEGG: sdy:SDY_2490 hypothetical protein; hypothetical protein 1488824 6068162 EcolC_1358 Escherichia coli ATCC 8739 hypothetical protein YP_001724351.1 1488330 D 481805 CDS YP_001724352.1 170019398 6068158 1488835..1489485 1 NC_010468.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfv:SFV_2360 putative phosphatase; putative phosphatase 1489485 6068158 EcolC_1359 Escherichia coli ATCC 8739 putative phosphatase YP_001724352.1 1488835 D 481805 CDS YP_001724353.1 170019399 6068156 1489572..1491404 1 NC_010468.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ssn:SSON_2349 putative transport protein; citrate transporter 1491404 6068156 EcolC_1360 Escherichia coli ATCC 8739 citrate transporter YP_001724353.1 1489572 D 481805 CDS YP_001724354.1 170019400 6068152 complement(1491463..1492062) 1 NC_010468.1 KEGG: sfv:SFV_2358 putative alpha helix protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; hypothetical protein 1492062 6068152 EcolC_1361 Escherichia coli ATCC 8739 hypothetical protein YP_001724354.1 1491463 R 481805 CDS YP_001724355.1 170019401 6068149 complement(1492146..1493363) 1 NC_010468.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1493363 6068149 EcolC_1362 Escherichia coli ATCC 8739 aminotransferase AlaT YP_001724355.1 1492146 R 481805 CDS YP_001724356.1 170019402 6068147 1494283..1495221 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2322 NADH dehydrogenase transcriptional regulator; LysR family transcriptional regulator 1495221 6068147 EcolC_1363 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001724356.1 1494283 D 481805 CDS YP_001724357.1 170019403 6068145 1495852..1496295 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 1496295 6068145 EcolC_1364 Escherichia coli ATCC 8739 NADH dehydrogenase subunit A YP_001724357.1 1495852 D 481805 CDS YP_001724358.1 170019404 6068143 1496311..1496973 1 NC_010468.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1496973 6068143 EcolC_1365 Escherichia coli ATCC 8739 NADH dehydrogenase subunit B YP_001724358.1 1496311 D 481805 CDS YP_001724359.1 170019405 6068139 1497067..1498869 1 NC_010468.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 1498869 6068139 EcolC_1366 Escherichia coli ATCC 8739 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_001724359.1 1497067 D 481805 CDS YP_001724360.1 170019406 6068137 1498872..1499372 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 1499372 6068137 EcolC_1367 Escherichia coli ATCC 8739 NADH dehydrogenase subunit E YP_001724360.1 1498872 D 481805 CDS YP_001724361.1 170019407 6068134 1499369..1500706 1 NC_010468.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 1500706 6068134 EcolC_1368 Escherichia coli ATCC 8739 NADH dehydrogenase I subunit F YP_001724361.1 1499369 D 481805 CDS YP_001724362.1 170019408 6068129 1500759..1503485 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 1503485 6068129 EcolC_1369 Escherichia coli ATCC 8739 NADH dehydrogenase subunit G YP_001724362.1 1500759 D 481805 CDS YP_001724363.1 170019409 6068123 1503482..1504459 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1504459 6068123 EcolC_1370 Escherichia coli ATCC 8739 NADH dehydrogenase subunit H YP_001724363.1 1503482 D 481805 CDS YP_001724364.1 170019410 6068120 1504474..1505016 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1505016 6068120 EcolC_1371 Escherichia coli ATCC 8739 NADH dehydrogenase subunit I YP_001724364.1 1504474 D 481805 CDS YP_001724365.1 170019411 6068117 1505028..1505582 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1505582 6068117 EcolC_1372 Escherichia coli ATCC 8739 NADH dehydrogenase subunit J YP_001724365.1 1505028 D 481805 CDS YP_001724366.1 170019412 6068107 1505579..1505881 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1505881 6068107 EcolC_1373 Escherichia coli ATCC 8739 NADH dehydrogenase subunit K YP_001724366.1 1505579 D 481805 CDS YP_001724367.1 170019413 6068098 1505878..1507719 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1507719 6068098 EcolC_1374 Escherichia coli ATCC 8739 NADH dehydrogenase subunit L YP_001724367.1 1505878 D 481805 CDS YP_001724368.1 170019414 6068083 1507883..1509412 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1509412 6068083 EcolC_1375 Escherichia coli ATCC 8739 NADH dehydrogenase subunit M YP_001724368.1 1507883 D 481805 CDS YP_001724369.1 170019415 6068078 1509419..1510876 1 NC_010468.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1510876 6068078 EcolC_1376 Escherichia coli ATCC 8739 NADH dehydrogenase subunit N YP_001724369.1 1509419 D 481805 CDS YP_001724370.1 170019416 6068072 complement(1510943..1511446) 1 NC_010468.1 PFAM: Domain of unknown function DUF1877; KEGG: sdy:SDY_2471 hypothetical protein; hypothetical protein 1511446 6068072 EcolC_1377 Escherichia coli ATCC 8739 hypothetical protein YP_001724370.1 1510943 R 481805 CDS YP_001724371.1 170019417 6068055 complement(1513995..1514912) 1 NC_010468.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 1514912 6068055 EcolC_1380 Escherichia coli ATCC 8739 ribonuclease Z YP_001724371.1 1513995 R 481805 CDS YP_001724372.1 170019418 6068047 1514977..1515438 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_2338 hypothetical protein; hypothetical protein 1515438 6068047 EcolC_1381 Escherichia coli ATCC 8739 hypothetical protein YP_001724372.1 1514977 D 481805 CDS YP_001724373.1 170019419 6068041 1515493..1515798 1 NC_010468.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2462 hypothetical protein; hypothetical protein 1515798 6068041 EcolC_1382 Escherichia coli ATCC 8739 hypothetical protein YP_001724373.1 1515493 D 481805 CDS YP_001724374.1 170019420 6068036 1515877..1517172 1 NC_010468.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: sfv:SFV_2336 isochorismate hydroxymutase 2; isochorismate synthase 1517172 6068036 EcolC_1383 Escherichia coli ATCC 8739 isochorismate synthase YP_001724374.1 1515877 D 481805 CDS YP_001724375.1 170019421 6068024 1517261..1518931 1 NC_010468.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1518931 6068024 EcolC_1384 Escherichia coli ATCC 8739 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_001724375.1 1517261 D 481805 CDS YP_001724376.1 170019422 6068015 1518928..1519686 1 NC_010468.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 1519686 6068015 EcolC_1385 Escherichia coli ATCC 8739 acyl-CoA thioester hydrolase YfbB YP_001724376.1 1518928 D 481805 CDS YP_001724377.1 170019423 6068005 1519701..1520558 1 NC_010468.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1520558 6068005 EcolC_1386 Escherichia coli ATCC 8739 naphthoate synthase YP_001724377.1 1519701 D 481805 CDS YP_001724378.1 170019424 6067995 1520558..1521520 1 NC_010468.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 1521520 6067995 EcolC_1387 Escherichia coli ATCC 8739 O-succinylbenzoate synthase YP_001724378.1 1520558 D 481805 CDS YP_001724379.1 170019425 6067985 1521517..1522872 1 NC_010468.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: sdy:SDY_2456 O-succinylbenzoate-CoA ligase; O-succinylbenzoic acid--CoA ligase 1522872 6067985 EcolC_1388 Escherichia coli ATCC 8739 O-succinylbenzoic acid--CoA ligase YP_001724379.1 1521517 D 481805 CDS YP_001724380.1 170019426 6067972 1522982..1523248 1 NC_010468.1 KEGG: ssn:SSON_2320 polymyxin resistance protein B; polymyxin resistance protein B 1523248 6067972 EcolC_1389 Escherichia coli ATCC 8739 polymyxin resistance protein B YP_001724380.1 1522982 D 481805 CDS YP_001724381.1 170019427 6067957 complement(1523242..1523628) 1 NC_010468.1 KEGG: sbo:SBO_2295 putative transport/receptor protein; hypothetical protein 1523628 6067957 EcolC_1390 Escherichia coli ATCC 8739 hypothetical protein YP_001724381.1 1523242 R 481805 CDS YP_001724382.1 170019428 6067952 complement(1523628..1523963) 1 NC_010468.1 PFAM: small multidrug resistance protein; KEGG: sfx:S2567 sucrose-6 phosphate hydrolase; small multidrug resistance protein 1523963 6067952 EcolC_1391 Escherichia coli ATCC 8739 small multidrug resistance protein YP_001724382.1 1523628 R 481805 CDS YP_001724383.1 170019429 6067949 complement(1523960..1525612) 1 NC_010468.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 1525612 arnT 6067949 arnT Escherichia coli ATCC 8739 4-amino-4-deoxy-L-arabinose transferase YP_001724383.1 1523960 R 481805 CDS YP_001724384.1 170019430 6067940 complement(1525612..1526502) 1 NC_010468.1 PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_2317 hypothetical protein; polysaccharide deacetylase 1526502 6067940 EcolC_1393 Escherichia coli ATCC 8739 polysaccharide deacetylase YP_001724384.1 1525612 R 481805 CDS YP_001724385.1 170019431 6067936 complement(1526499..1528481) 1 NC_010468.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 1528481 6067936 EcolC_1394 Escherichia coli ATCC 8739 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_001724385.1 1526499 R 481805 CDS YP_001724386.1 170019432 6067920 complement(1528481..1529449) 1 NC_010468.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 1529449 6067920 EcolC_1395 Escherichia coli ATCC 8739 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_001724386.1 1528481 R 481805 CDS YP_001724387.1 170019433 6067914 complement(1529453..1530592) 1 NC_010468.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 1530592 6067914 EcolC_1396 Escherichia coli ATCC 8739 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_001724387.1 1529453 R 481805 CDS YP_001724388.1 170019434 6067908 1530900..1531502 1 NC_010468.1 PFAM: Phosphoglycerate mutase; KEGG: ssn:SSON_2313 protein induced by aluminum; phosphoglycerate mutase 1531502 6067908 EcolC_1397 Escherichia coli ATCC 8739 phosphoglycerate mutase YP_001724388.1 1530900 D 481805 CDS YP_001724389.1 170019435 6067905 complement(1531541..1531966) 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2321 hypothetical protein; NUDIX hydrolase 1531966 6067905 EcolC_1398 Escherichia coli ATCC 8739 NUDIX hydrolase YP_001724389.1 1531541 R 481805 CDS YP_001724390.1 170019436 6067897 1532245..1532787 1 NC_010468.1 PFAM: YfaZ family protein; KEGG: ssn:SSON_2311 hypothetical protein; hypothetical protein 1532787 6067897 EcolC_1399 Escherichia coli ATCC 8739 hypothetical protein YP_001724390.1 1532245 D 481805 CDS YP_001724391.1 170019437 6067885 1532887..1534089 1 NC_010468.1 TIGRFAM: molybdenum cofactor synthesis domain protein; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: sfx:S2461 competence/damage-inducible protein CinA; competence damage-inducible protein A 1534089 6067885 EcolC_1400 Escherichia coli ATCC 8739 competence damage-inducible protein A YP_001724391.1 1532887 D 481805 CDS YP_001724392.1 170019438 6067878 1534309..1535091 1 NC_010468.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ssn:SSON_2309 putative regulator; IclR family transcriptional regulator 1535091 6067878 EcolC_1401 Escherichia coli ATCC 8739 IclR family transcriptional regulator YP_001724392.1 1534309 D 481805 CDS YP_001724393.1 170019439 6067871 1535106..1536311 1 NC_010468.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sbo:SBO_2047 putative racemase; mandelate racemase/muconate lactonizing protein 1536311 6067871 EcolC_1402 Escherichia coli ATCC 8739 mandelate racemase/muconate lactonizing protein YP_001724393.1 1535106 D 481805 CDS YP_001724394.1 170019440 6067866 1536368..1537657 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2048 putative transport protein; major facilitator transporter 1537657 6067866 EcolC_1403 Escherichia coli ATCC 8739 major facilitator transporter YP_001724394.1 1536368 D 481805 CDS YP_001724395.1 170019441 6067853 1537675..1538478 1 NC_010468.1 PFAM: HpcH/HpaI aldolase; KEGG: ssn:SSON_2306 hypothetical protein; putative aldolase 1538478 6067853 EcolC_1404 Escherichia coli ATCC 8739 putative aldolase YP_001724395.1 1537675 D 481805 CDS YP_001724396.1 170019442 6067849 complement(1538717..1539616) 1 NC_010468.1 PFAM: putative transposase YhgA family protein; KEGG: sbo:SBO_2050 hypothetical protein; hypothetical protein 1539616 6067849 EcolC_1406 Escherichia coli ATCC 8739 hypothetical protein YP_001724396.1 1538717 R 481805 CDS YP_001724397.1 170019443 6067844 complement(1539659..1539784) 1 NC_010468.1 hypothetical protein 1539784 6067844 EcolC_1407 Escherichia coli ATCC 8739 hypothetical protein YP_001724397.1 1539659 R 481805 CDS YP_001724398.1 170019444 6067836 complement(1539809..1540999) 1 NC_010468.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 1540999 glpC 6067836 glpC Escherichia coli ATCC 8739 sn-glycerol-3-phosphate dehydrogenase subunit C YP_001724398.1 1539809 R 481805 CDS YP_001724399.1 170019445 6067831 complement(1540996..1542255) 1 NC_010468.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 1542255 6067831 EcolC_1409 Escherichia coli ATCC 8739 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_001724399.1 1540996 R 481805 CDS YP_001724400.1 170019446 6067823 complement(1542245..1543873) 1 NC_010468.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 1543873 glpA 6067823 glpA Escherichia coli ATCC 8739 sn-glycerol-3-phosphate dehydrogenase subunit A YP_001724400.1 1542245 R 481805 CDS YP_001724401.1 170019447 6067811 1544146..1545504 1 NC_010468.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 1545504 glpT 6067811 glpT Escherichia coli ATCC 8739 sn-glycerol-3-phosphate transporter YP_001724401.1 1544146 D 481805 CDS YP_001724402.1 170019448 6067805 1545509..1546585 1 NC_010468.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 1546585 glpQ 6067805 glpQ Escherichia coli ATCC 8739 glycerophosphodiester phosphodiesterase YP_001724402.1 1545509 D 481805 CDS YP_001724403.1 170019449 6067797 complement(1546627..1546833) 1 NC_010468.1 KEGG: sbo:SBO_2056 hypothetical protein; hypothetical protein 1546833 6067797 EcolC_1413 Escherichia coli ATCC 8739 hypothetical protein YP_001724403.1 1546627 R 481805 CDS YP_001724404.1 170019450 6067793 1547048..1547698 1 NC_010468.1 PFAM: lipopolysaccharide kinase; KEGG: sfv:SFV_2310 pH-inducible protein involved in stress response; hypothetical protein 1547698 6067793 EcolC_1414 Escherichia coli ATCC 8739 hypothetical protein YP_001724404.1 1547048 D 481805 CDS YP_001724405.1 170019451 6067779 complement(1547752..1548006) 1 NC_010468.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 1548006 6067779 EcolC_1415 Escherichia coli ATCC 8739 2Fe-2S ferredoxin YP_001724405.1 1547752 R 481805 CDS YP_001724406.1 170019452 6067771 complement(1548006..1549175) 1 NC_010468.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1549175 nrdB 6067771 nrdB Escherichia coli ATCC 8739 ribonucleotide-diphosphate reductase subunit beta YP_001724406.1 1548006 R 481805 CDS YP_001724407.1 170019453 6067765 complement(1549370..1551655) 1 NC_010468.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1551655 6067765 EcolC_1417 Escherichia coli ATCC 8739 ribonucleotide-diphosphate reductase subunit alpha YP_001724407.1 1549370 R 481805 CDS YP_001724408.1 170019454 6067759 1552399..1556103 1 NC_010468.1 TIGRFAM: polymorphic outer membrane protein; outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Polymorphic membrane protein Chlamydia; Pertactin; Autotransporter beta- domain protein; KEGG: sdy:SDY_2425 putative ATP-binding component of a transport system; adhesin 1556103 6067759 EcolC_1418 Escherichia coli ATCC 8739 adhesin YP_001724408.1 1552399 D 481805 CDS YP_001724409.1 170019455 6067748 complement(1556231..1556953) 1 NC_010468.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1556953 6067748 EcolC_1419 Escherichia coli ATCC 8739 3-demethylubiquinone-9 3-methyltransferase YP_001724409.1 1556231 R 481805 CDS YP_001724410.1 170019456 6067746 1557100..1559727 1 NC_010468.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1559727 6067746 EcolC_1420 Escherichia coli ATCC 8739 DNA gyrase subunit A YP_001724410.1 1557100 D 481805 CDS YP_001724411.1 170019457 6067734 1559876..1561564 1 NC_010468.1 KEGG: ssn:SSON_2288 hypothetical protein; hypothetical protein 1561564 6067734 EcolC_1421 Escherichia coli ATCC 8739 hypothetical protein YP_001724411.1 1559876 D 481805 CDS YP_001724412.1 170019458 6067718 1561561..1562184 1 NC_010468.1 PFAM: protein of unknown function DUF1175; KEGG: sfv:SFV_2299 hypothetical protein; hypothetical protein 1562184 6067718 EcolC_1422 Escherichia coli ATCC 8739 hypothetical protein YP_001724412.1 1561561 D 481805 CDS YP_001724413.1 170019459 6067710 1562208..1566722 1 NC_010468.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: sdy:SDY_0852 large extracellular alpha-helical protein; alpha-2-macroglobulin domain-containing protein 1566722 6067710 EcolC_1423 Escherichia coli ATCC 8739 alpha-2-macroglobulin domain-containing protein YP_001724413.1 1562208 D 481805 CDS YP_001724414.1 170019460 6067697 1566723..1568372 1 NC_010468.1 KEGG: ssn:SSON_2285 hypothetical protein; hypothetical protein 1568372 6067697 EcolC_1424 Escherichia coli ATCC 8739 hypothetical protein YP_001724414.1 1566723 D 481805 CDS YP_001724415.1 170019461 6067693 1568377..1569153 1 NC_010468.1 KEGG: sfv:SFV_2294 hypothetical protein; hypothetical protein 1569153 6067693 EcolC_1425 Escherichia coli ATCC 8739 hypothetical protein YP_001724415.1 1568377 D 481805 CDS YP_001724416.1 170019462 6067686 complement(1569227..1570411) 1 NC_010468.1 KEGG: ssn:SSON_2283 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase 1570411 6067686 EcolC_1426 Escherichia coli ATCC 8739 acetyl-CoA acetyltransferase YP_001724416.1 1569227 R 481805 CDS YP_001724417.1 170019463 6067684 complement(1570442..1571764) 1 NC_010468.1 PFAM: short chain fatty acid transporter; KEGG: ssn:SSON_2282 short chain fatty acid transporter; short chain fatty acid transporter 1571764 6067684 EcolC_1427 Escherichia coli ATCC 8739 short chain fatty acid transporter YP_001724417.1 1570442 R 481805 CDS YP_001724418.1 170019464 6067681 complement(1571761..1572411) 1 NC_010468.1 KEGG: ssn:SSON_2281 acetyl-CoA:acetoacetyl-CoA transferase beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit B 1572411 6067681 EcolC_1428 Escherichia coli ATCC 8739 3-oxoacid CoA-transferase subunit B YP_001724418.1 1571761 R 481805 CDS YP_001724419.1 170019465 6067670 complement(1572411..1573073) 1 NC_010468.1 KEGG: ssn:SSON_2280 acetyl-CoA:acetoacetyl-CoA transferase alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 1573073 6067670 EcolC_1429 Escherichia coli ATCC 8739 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_001724419.1 1572411 R 481805 CDS YP_001724420.1 170019466 6067656 complement(1573269..1574654) 1 NC_010468.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 1574654 6067656 EcolC_1430 Escherichia coli ATCC 8739 acetoacetate metabolism regulatory protein AtoC YP_001724420.1 1573269 R 481805 CDS YP_001724421.1 170019467 6067643 complement(1574651..1576477) 1 NC_010468.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 1576477 6067643 EcolC_1431 Escherichia coli ATCC 8739 sensory histidine kinase AtoS YP_001724421.1 1574651 R 481805 CDS YP_001724422.1 170019468 6067640 1576644..1579493 1 NC_010468.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase; KEGG: sfx:S2433 sensor for ctr capsule biosynthesis, probable histidine kinase acting on RcsB; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 1579493 6067640 EcolC_1432 Escherichia coli ATCC 8739 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_001724422.1 1576644 D 481805 CDS YP_001724423.1 170019469 6067621 complement(1579693..1580343) 1 NC_010468.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 1580343 6067621 EcolC_1433 Escherichia coli ATCC 8739 transcriptional regulator RcsB YP_001724423.1 1579693 R 481805 CDS YP_001724424.1 170019470 6067602 complement(1580360..1583032) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: sbo:SBO_2091 putative 2-component sensor protein; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 1583032 6067602 EcolC_1434 Escherichia coli ATCC 8739 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_001724424.1 1580360 R 481805 CDS YP_001724425.1 170019471 6067592 1583771..1584901 1 NC_010468.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 1584901 6067592 EcolC_1435 Escherichia coli ATCC 8739 outer membrane porin protein C YP_001724425.1 1583771 D 481805 CDS YP_001724426.1 170019472 6067573 1585013..1586068 1 NC_010468.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 1586068 6067573 EcolC_1436 Escherichia coli ATCC 8739 thiamine biosynthesis lipoprotein ApbE YP_001724426.1 1585013 D 481805 CDS YP_001724427.1 170019473 6067560 1586142..1587206 1 NC_010468.1 KEGG: sbo:SBO_2094 O6-methylguanine-DNA methyltransferase; transcription activator/repressor; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; AraC family transcriptional regulator 1587206 6067560 EcolC_1437 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001724427.1 1586142 D 481805 CDS YP_001724428.1 170019474 6067548 1587206..1587856 1 NC_010468.1 TIGRFAM: alkylated DNA repair protein AlkB; PFAM: 2OG-Fe(II) oxygenase; KEGG: sbo:SBO_2095 AlkB; alkylated DNA repair protein AlkB 1587856 6067548 EcolC_1438 Escherichia coli ATCC 8739 alkylated DNA repair protein AlkB YP_001724428.1 1587206 D 481805 CDS YP_001724429.1 170019475 6067542 1587932..1589575 1 NC_010468.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding protein 1589575 6067542 EcolC_1439 Escherichia coli ATCC 8739 multidrug transporter membrane component/ATP-binding protein YP_001724429.1 1587932 D 481805 CDS YP_001724430.1 170019476 6067525 1589793..1591439 1 NC_010468.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1591439 6067525 EcolC_1440 Escherichia coli ATCC 8739 malate:quinone oxidoreductase YP_001724430.1 1589793 D 481805 CDS YP_001724431.1 170019477 6067509 complement(1592156..1592644) 1 NC_010468.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 1592644 6067509 EcolC_1441 Escherichia coli ATCC 8739 ecotin YP_001724431.1 1592156 R 481805 CDS YP_001724432.1 170019478 6067491 1593052..1593546 1 NC_010468.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 1593546 6067491 EcolC_1442 Escherichia coli ATCC 8739 ferredoxin-type protein YP_001724432.1 1593052 D 481805 CDS YP_001724433.1 170019479 6067482 1593536..1593799 1 NC_010468.1 PFAM: NapD family protein; KEGG: sbo:SBO_2100 hypothetical protein; assembly protein for periplasmic nitrate reductase 1593799 6067482 EcolC_1443 Escherichia coli ATCC 8739 assembly protein for periplasmic nitrate reductase YP_001724433.1 1593536 D 481805 CDS YP_001724434.1 170019480 6067475 1593796..1596282 1 NC_010468.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 1596282 6067475 EcolC_1444 Escherichia coli ATCC 8739 nitrate reductase catalytic subunit YP_001724434.1 1593796 D 481805 CDS YP_001724435.1 170019481 6067453 1596289..1596984 1 NC_010468.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic protein 1596984 napG 6067453 napG Escherichia coli ATCC 8739 quinol dehydrogenase periplasmic protein YP_001724435.1 1596289 D 481805 CDS YP_001724436.1 170019482 6067439 1596971..1597834 1 NC_010468.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane protein 1597834 napH 6067439 napH Escherichia coli ATCC 8739 quinol dehydrogenase membrane protein YP_001724436.1 1596971 D 481805 CDS YP_001724437.1 170019483 6067424 1597831..1598280 1 NC_010468.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 1598280 napB 6067424 napB Escherichia coli ATCC 8739 citrate reductase cytochrome c-type subunit YP_001724437.1 1597831 D 481805 CDS YP_001724438.1 170019484 6067401 1598290..1598892 1 NC_010468.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 1598892 6067401 EcolC_1448 Escherichia coli ATCC 8739 cytochrome c-type protein NapC YP_001724438.1 1598290 D 481805 CDS YP_001724439.1 170019485 6067395 1598911..1599528 1 NC_010468.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1599528 6067395 EcolC_1449 Escherichia coli ATCC 8739 cytochrome c biogenesis protein CcmA YP_001724439.1 1598911 D 481805 CDS YP_001724440.1 170019486 6067393 1599525..1600187 1 NC_010468.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: sdy:SDY_0878 heme exporter protein B; heme exporter protein CcmB 1600187 6067393 EcolC_1450 Escherichia coli ATCC 8739 heme exporter protein CcmB YP_001724440.1 1599525 D 481805 CDS YP_001724441.1 170019487 6067389 1600229..1600966 1 NC_010468.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: sdy:SDY_0879 heme exporter protein C; heme exporter protein CcmC 1600966 6067389 EcolC_1451 Escherichia coli ATCC 8739 heme exporter protein CcmC YP_001724441.1 1600229 D 481805 CDS YP_001724442.1 170019488 6067370 1600963..1601172 1 NC_010468.1 TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: sdy:SDY_0880 heme exporter protein C; heme exporter protein CcmD 1601172 6067370 EcolC_1452 Escherichia coli ATCC 8739 heme exporter protein CcmD YP_001724442.1 1600963 D 481805 CDS YP_001724443.1 170019489 6067365 1601169..1601648 1 NC_010468.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 1601648 6067365 EcolC_1453 Escherichia coli ATCC 8739 cytochrome c-type biogenesis protein CcmE YP_001724443.1 1601169 D 481805 CDS YP_001724444.1 170019490 6067355 1601645..1603588 1 NC_010468.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: sbo:SBO_2111 cytochrome c-type biogenesis protein; cytochrome c-type biogenesis protein CcmF 1603588 6067355 EcolC_1454 Escherichia coli ATCC 8739 cytochrome c-type biogenesis protein CcmF YP_001724444.1 1601645 D 481805 CDS YP_001724445.1 170019491 6067342 1603585..1604142 1 NC_010468.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sbo:SBO_2112 disulfide oxidoreductase; periplasmic protein thiol--disulfide oxidoreductase DsbE 1604142 6067342 EcolC_1455 Escherichia coli ATCC 8739 periplasmic protein thiol--disulfide oxidoreductase DsbE YP_001724445.1 1603585 D 481805 CDS YP_001724446.1 170019492 6067334 1604139..1605191 1 NC_010468.1 PFAM: cytochrome C biogenesis protein; KEGG: sfv:SFV_2270 possible subunit of heme lyase; cytochrome C biogenesis protein 1605191 6067334 EcolC_1456 Escherichia coli ATCC 8739 cytochrome C biogenesis protein YP_001724446.1 1604139 D 481805 CDS YP_001724447.1 170019493 6067321 complement(1605226..1605873) 1 NC_010468.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 1605873 6067321 EcolC_1457 Escherichia coli ATCC 8739 transcriptional regulator NarP YP_001724447.1 1605226 R 481805 CDS YP_001724448.1 170019494 6067311 1606193..1608784 1 NC_010468.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfv:SFV_2268 putative ATP-binding component of a transport system; outer membrane autotransporter 1608784 6067311 EcolC_1458 Escherichia coli ATCC 8739 outer membrane autotransporter YP_001724448.1 1606193 D 481805 CDS YP_001724449.1 170019495 6067304 complement(1609038..1610798) 1 NC_010468.1 PFAM: sulfatase; KEGG: ssn:SSON_2244 putative sulfatase; sulfatase 1610798 6067304 EcolC_1459 Escherichia coli ATCC 8739 sulfatase YP_001724449.1 1609038 R 481805 CDS YP_001724450.1 170019496 6067288 complement(1610818..1611045) 1 NC_010468.1 PFAM: protein of unknown function DUF1414; KEGG: sbo:SBO_2137 hypothetical protein; hypothetical protein 1611045 6067288 EcolC_1460 Escherichia coli ATCC 8739 hypothetical protein YP_001724450.1 1610818 R 481805 CDS YP_001724451.1 170019497 6067286 1611227..1612234 1 NC_010468.1 PFAM: 37kDa nucleoid-associated protein; KEGG: sdy:SDY_0893 hypothetical protein; nucleoid-associated protein NdpA 1612234 6067286 EcolC_1461 Escherichia coli ATCC 8739 nucleoid-associated protein NdpA YP_001724451.1 1611227 D 481805 CDS YP_001724452.1 170019498 6067280 complement(1612373..1612657) 1 NC_010468.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1612657 6067280 EcolC_1462 Escherichia coli ATCC 8739 50S ribosomal protein L25 YP_001724452.1 1612373 R 481805 CDS YP_001724453.1 170019499 6067277 complement(1612782..1614542) 1 NC_010468.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sdy:SDY_0895 putative ATP-dependent helicase; type III restriction protein res subunit 1614542 6067277 EcolC_1463 Escherichia coli ATCC 8739 type III restriction protein res subunit YP_001724453.1 1612782 R 481805 CDS YP_001724454.1 170019500 6067263 1614691..1615386 1 NC_010468.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 1615386 6067263 EcolC_1464 Escherichia coli ATCC 8739 16S rRNA pseudouridylate synthase A YP_001724454.1 1614691 D 481805 CDS YP_001724455.1 170019501 6067255 1615414..1616604 1 NC_010468.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 1616604 6067255 EcolC_1465 Escherichia coli ATCC 8739 bicyclomycin/multidrug efflux system protein YP_001724455.1 1615414 D 481805 CDS YP_001724456.1 170019502 6067250 1616937..1617281 1 NC_010468.1 KEGG: sdy:SDY_0898 hypothetical protein; hypothetical protein 1617281 6067250 EcolC_1466 Escherichia coli ATCC 8739 hypothetical protein YP_001724456.1 1616937 D 481805 CDS YP_001724457.1 170019503 6067246 complement(1617285..1618874) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_0899 putative ATP-binding component of a transport system; ABC transporter-like protein 1618874 6067246 EcolC_1467 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001724457.1 1617285 R 481805 CDS YP_001724458.1 170019504 6067242 complement(1618876..1619901) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_2145 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 1619901 6067242 EcolC_1468 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001724458.1 1618876 R 481805 CDS YP_001724459.1 170019505 6067239 complement(1619901..1620995) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2234 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 1620995 6067239 EcolC_1469 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001724459.1 1619901 R 481805 CDS YP_001724460.1 170019506 6067227 complement(1620996..1622810) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: sdy:SDY_0902 hypothetical protein; extracellular solute-binding protein 1622810 6067227 EcolC_1470 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001724460.1 1620996 R 481805 CDS YP_001724461.1 170019507 6067225 complement(1622892..1624448) 1 NC_010468.1 PFAM: EAL domain protein; KEGG: sdy:SDY_0903 hypothetical protein; hypothetical protein 1624448 6067225 EcolC_1471 Escherichia coli ATCC 8739 hypothetical protein YP_001724461.1 1622892 R 481805 CDS YP_001724462.1 170019508 6067223 complement(1624629..1625195) 1 NC_010468.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 1625195 spr 6067223 spr Escherichia coli ATCC 8739 putative outer membrane lipoprotein YP_001724462.1 1624629 R 481805 CDS YP_001724463.1 170019509 6067216 complement(1625607..1626320) 1 NC_010468.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_2230 hypothetical protein; PA-phosphatase-like phosphoesterase 1626320 6067216 EcolC_1473 Escherichia coli ATCC 8739 PA-phosphatase-like phosphoesterase YP_001724463.1 1625607 R 481805 CDS YP_001724464.1 170019510 6067208 complement(1626359..1627345) 1 NC_010468.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sfx:S2389 hypothetical protein; cobalamin synthesis protein P47K 1627345 6067208 EcolC_1474 Escherichia coli ATCC 8739 cobalamin synthesis protein P47K YP_001724464.1 1626359 R 481805 CDS YP_001724465.1 170019511 6067202 complement(1627463..1628929) 1 NC_010468.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ssn:SSON_2228 putative oxidoreductase; mannitol dehydrogenase domain-containing protein 1628929 6067202 EcolC_1475 Escherichia coli ATCC 8739 mannitol dehydrogenase domain-containing protein YP_001724465.1 1627463 R 481805 CDS YP_001724466.1 170019512 6067193 complement(1629152..1629724) 1 NC_010468.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 1629724 6067193 EcolC_1476 Escherichia coli ATCC 8739 elongation factor P YP_001724466.1 1629152 R 481805 CDS YP_001724467.1 170019513 6067198 1629879..1630133 1 NC_010468.1 PFAM: protein of unknown function UPF0153; KEGG: ent:Ent638_2765 protein of unknown function UPF0153; hypothetical protein 1630133 6067198 EcolC_1477 Escherichia coli ATCC 8739 hypothetical protein YP_001724467.1 1629879 D 481805 CDS YP_001724468.1 170019514 6067190 complement(1630130..1631311) 1 NC_010468.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2226 putative transport; sugar efflux transporter 1631311 6067190 EcolC_1478 Escherichia coli ATCC 8739 sugar efflux transporter YP_001724468.1 1630130 R 481805 CDS YP_001724469.1 170019515 6067187 1631679..1632809 1 NC_010468.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 1632809 6067187 EcolC_1479 Escherichia coli ATCC 8739 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_001724469.1 1631679 D 481805 CDS YP_001724470.1 170019516 6067175 1632809..1633747 1 NC_010468.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 1633747 fruK 6067175 fruK Escherichia coli ATCC 8739 1-phosphofructokinase YP_001724470.1 1632809 D 481805 CDS YP_001724471.1 170019517 6067169 1633764..1635455 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 1635455 6067169 EcolC_1481 Escherichia coli ATCC 8739 PTS system fructose-specific transporter subunit IIBC YP_001724471.1 1633764 D 481805 CDS YP_001724472.1 170019518 6067167 1635879..1636820 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: sfv:SFV_2241 putative kinase; hypothetical protein 1636820 6067167 EcolC_1482 Escherichia coli ATCC 8739 hypothetical protein YP_001724472.1 1635879 D 481805 CDS YP_001724473.1 170019519 6067153 1636808..1637746 1 NC_010468.1 PFAM: Indigoidine synthase A family protein; KEGG: sfv:SFV_2240 hypothetical protein; indigoidine synthase A family protein 1637746 6067153 EcolC_1483 Escherichia coli ATCC 8739 indigoidine synthase A family protein YP_001724473.1 1636808 D 481805 CDS YP_001724474.1 170019520 6067149 1637840..1639090 1 NC_010468.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sfv:SFV_2239 putative transport system permease protein; nucleoside transporter 1639090 6067149 EcolC_1484 Escherichia coli ATCC 8739 nucleoside transporter YP_001724474.1 1637840 D 481805 CDS YP_001724475.1 170019521 6067144 complement(1639161..1639820) 1 NC_010468.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 1639820 6067144 EcolC_1485 Escherichia coli ATCC 8739 DNA-binding transcriptional activator YeiL YP_001724475.1 1639161 R 481805 CDS YP_001724476.1 170019522 6067145 1639989..1640930 1 NC_010468.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 1640930 rihB 6067145 rihB Escherichia coli ATCC 8739 ribonucleoside hydrolase 2 YP_001724476.1 1639989 D 481805 CDS YP_001724477.1 170019523 6067137 complement(1642336..1643424) 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_2167 putative kinase; hypothetical protein 1643424 6067137 EcolC_1488 Escherichia coli ATCC 8739 hypothetical protein YP_001724477.1 1642336 R 481805 CDS YP_001724478.1 170019524 6067135 complement(1643427..1644284) 1 NC_010468.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 1644284 6067135 EcolC_1489 Escherichia coli ATCC 8739 endonuclease IV YP_001724478.1 1643427 R 481805 CDS YP_001724479.1 170019525 6067130 complement(1644358..1645407) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2169 hypothetical protein; hypothetical protein 1645407 6067130 EcolC_1490 Escherichia coli ATCC 8739 hypothetical protein YP_001724479.1 1644358 R 481805 CDS YP_001724480.1 170019526 6067126 1645581..1646387 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_2213 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 1646387 6067126 EcolC_1491 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001724480.1 1645581 D 481805 CDS YP_001724481.1 170019527 6067124 1646592..1648061 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2110 lysine-specific permease; lysine transporter 1648061 6067124 EcolC_1492 Escherichia coli ATCC 8739 lysine transporter YP_001724481.1 1646592 D 481805 CDS YP_001724482.1 170019528 6067120 1648355..1650346 1 NC_010468.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 1650346 6067120 EcolC_1493 Escherichia coli ATCC 8739 colicin I receptor YP_001724482.1 1648355 D 481805 CDS YP_001724483.1 170019529 6067116 complement(1650378..1651214) 1 NC_010468.1 KEGG: sbo:SBO_2173 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; S-formylglutathione hydrolase 1651214 6067116 EcolC_1494 Escherichia coli ATCC 8739 S-formylglutathione hydrolase YP_001724483.1 1650378 R 481805 CDS YP_001724484.1 170019530 6067118 1651472..1652140 1 NC_010468.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1652140 folE 6067118 folE Escherichia coli ATCC 8739 GTP cyclohydrolase I YP_001724484.1 1651472 D 481805 CDS YP_001724485.1 170019531 6067114 1652157..1653314 1 NC_010468.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: sbo:SBO_2175 hypothetical protein; hypothetical protein 1653314 6067114 EcolC_1496 Escherichia coli ATCC 8739 hypothetical protein YP_001724485.1 1652157 D 481805 CDS YP_001724486.1 170019532 6067110 1653456..1654496 1 NC_010468.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 1654496 6067110 EcolC_1497 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator GalS YP_001724486.1 1653456 D 481805 CDS YP_001724487.1 170019533 6067108 1654776..1655774 1 NC_010468.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sdy:SDY_2130 galactose-binding transport protein; periplasmic binding protein/LacI transcriptional regulator 1655774 6067108 EcolC_1498 Escherichia coli ATCC 8739 periplasmic binding protein/LacI transcriptional regulator YP_001724487.1 1654776 D 481805 CDS YP_001724488.1 170019534 6067106 1655835..1657355 1 NC_010468.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1657355 6067106 EcolC_1499 Escherichia coli ATCC 8739 galactose/methyl galaxtoside transporter ATP-binding protein YP_001724488.1 1655835 D 481805 CDS YP_001724489.1 170019535 6067097 1657371..1658381 1 NC_010468.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 1658381 mglC 6067097 mglC Escherichia coli ATCC 8739 beta-methylgalactoside transporter inner membrane protein YP_001724489.1 1657371 D 481805 CDS YP_001724490.1 170019536 6067096 complement(1658452..1659687) 1 NC_010468.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 1659687 6067096 EcolC_1501 Escherichia coli ATCC 8739 dihydropyrimidine dehydrogenase YP_001724490.1 1658452 R 481805 CDS YP_001724491.1 170019537 6067093 complement(1659681..1660919) 1 NC_010468.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 1660919 6067093 EcolC_1502 Escherichia coli ATCC 8739 putative oxidoreductase YP_001724491.1 1659681 R 481805 CDS YP_001724492.1 170019538 6067090 complement(1661113..1661352) 1 NC_010468.1 KEGG: sbo:SBO_0996 hypothetical protein; hypothetical protein 1661352 6067090 EcolC_1503 Escherichia coli ATCC 8739 hypothetical protein YP_001724492.1 1661113 R 481805 CDS YP_001724493.1 170019539 6067091 complement(1661355..1662074) 1 NC_010468.1 PFAM: protein of unknown function DUF218; KEGG: sdy:SDY_2143 vancomycin sensitivity; hypothetical protein 1662074 6067091 EcolC_1504 Escherichia coli ATCC 8739 hypothetical protein YP_001724493.1 1661355 R 481805 CDS YP_001724494.1 170019540 6067089 complement(1662224..1663108) 1 NC_010468.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1663108 6067089 EcolC_1505 Escherichia coli ATCC 8739 cytidine deaminase YP_001724494.1 1662224 R 481805 CDS YP_001724495.1 170019541 6067079 complement(1663238..1663933) 1 NC_010468.1 PFAM: LrgB family protein; KEGG: ssn:SSON_2198 putative seritonin transporter; hypothetical protein 1663933 6067079 EcolC_1506 Escherichia coli ATCC 8739 hypothetical protein YP_001724495.1 1663238 R 481805 CDS YP_001724496.1 170019542 6067072 complement(1663930..1664328) 1 NC_010468.1 PFAM: LrgA family protein; KEGG: sbo:SBO_1000 hypothetical protein; hypothetical protein 1664328 6067072 EcolC_1507 Escherichia coli ATCC 8739 hypothetical protein YP_001724496.1 1663930 R 481805 CDS YP_001724497.1 170019543 6067069 1664567..1665514 1 NC_010468.1 PFAM: dihydrouridine synthase DuS; KEGG: ssn:SSON_2196 putative regulator protein; tRNA-dihydrouridine synthase C 1665514 6067069 EcolC_1508 Escherichia coli ATCC 8739 tRNA-dihydrouridine synthase C YP_001724497.1 1664567 D 481805 CDS YP_001724498.1 170019544 6067066 1666194..1667630 1 NC_010468.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 1667630 6067066 EcolC_1509 Escherichia coli ATCC 8739 multidrug resistance outer membrane protein MdtQ YP_001724498.1 1666194 D 481805 CDS YP_001724499.1 170019545 6067065 1667683..1668444 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbo:SBO_1007 putative oxidoreductase; acetoin dehydrogenase 1668444 6067065 EcolC_1510 Escherichia coli ATCC 8739 acetoin dehydrogenase YP_001724499.1 1667683 D 481805 CDS YP_001724500.1 170019546 6067036 complement(1668574..1669152) 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_1008 hypothetical protein; hypothetical protein 1669152 6067036 EcolC_1511 Escherichia coli ATCC 8739 hypothetical protein YP_001724500.1 1668574 R 481805 CDS YP_001724501.1 170019547 6067020 1669322..1669909 1 NC_010468.1 PFAM: protein of unknown function DUF1282; KEGG: sbo:SBO_1009 hypothetical protein; hypothetical protein 1669909 6067020 EcolC_1512 Escherichia coli ATCC 8739 hypothetical protein YP_001724501.1 1669322 D 481805 CDS YP_001724502.1 170019548 6067025 1670074..1671015 1 NC_010468.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 1671015 pbpG 6067025 pbpG Escherichia coli ATCC 8739 D-alanyl-D-alanine endopeptidase YP_001724502.1 1670074 D 481805 CDS YP_001724503.1 170019549 6067019 complement(1671053..1672768) 1 NC_010468.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 1672768 6067019 EcolC_1514 Escherichia coli ATCC 8739 D-lactate dehydrogenase YP_001724503.1 1671053 R 481805 CDS YP_001724504.1 170019550 6067004 1672964..1675261 1 NC_010468.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: ssn:SSON_2189 beta-D-glucoside glucohydrolase, periplasmic; glycoside hydrolase family protein 1675261 6067004 EcolC_1515 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001724504.1 1672964 D 481805 CDS YP_001724505.1 170019551 6066985 1675513..1676430 1 NC_010468.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ssn:SSON_2188 putative transport system permease protein; glycine betaine ABC transporter substrate-binding protein 1676430 6066985 EcolC_1516 Escherichia coli ATCC 8739 glycine betaine ABC transporter substrate-binding protein YP_001724505.1 1675513 D 481805 CDS YP_001724506.1 170019552 6066963 1676437..1677594 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2187 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 1677594 6066963 EcolC_1517 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001724506.1 1676437 D 481805 CDS YP_001724507.1 170019553 6066934 1677587..1678513 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_2186 putative ATP-binding component of a transport system; ABC transporter-like protein 1678513 6066934 EcolC_1518 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001724507.1 1677587 D 481805 CDS YP_001724508.1 170019554 6066933 1678518..1679249 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2185 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 1679249 6066933 EcolC_1519 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001724508.1 1678518 D 481805 CDS YP_001724509.1 170019555 6066931 complement(1679397..1680128) 1 NC_010468.1 PFAM: regulatory protein MerR; KEGG: sdy:SDY_2162 putative transcriptional regulator; MerR family transcriptional regulator 1680128 6066931 EcolC_1520 Escherichia coli ATCC 8739 MerR family transcriptional regulator YP_001724509.1 1679397 R 481805 CDS YP_001724510.1 170019556 6066922 1680350..1682035 1 NC_010468.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: sfx:S2325 putative 2-component sensor protein; signal transduction histidine kinase LytS 1682035 6066922 EcolC_1521 Escherichia coli ATCC 8739 signal transduction histidine kinase LytS YP_001724510.1 1680350 D 481805 CDS YP_001724511.1 170019557 6066924 1682032..1682751 1 NC_010468.1 unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 1682751 6066924 EcolC_1522 Escherichia coli ATCC 8739 putative two-component response-regulatory protein YehT YP_001724511.1 1682032 D 481805 CDS YP_001724512.1 170019558 6066269 1682798..1683268 1 NC_010468.1 PFAM: protein of unknown function DUF1456; KEGG: sdy:SDY_2165 hypothetical protein; hypothetical protein 1683268 6066269 EcolC_1523 Escherichia coli ATCC 8739 hypothetical protein YP_001724512.1 1682798 D 481805 CDS YP_001724513.1 170019559 6066913 complement(1683309..1683770) 1 NC_010468.1 PFAM: protein of unknown function DUF1307; KEGG: ssn:SSON_2169 hypothetical protein; hypothetical protein 1683770 6066913 EcolC_1524 Escherichia coli ATCC 8739 hypothetical protein YP_001724513.1 1683309 R 481805 CDS YP_001724514.1 170019560 6066782 complement(1683895..1685898) 1 NC_010468.1 PFAM: zinc finger SWIM domain protein; KEGG: sfx:S2316 hypothetical protein; zinc finger SWIM domain-containing protein 1685898 6066782 EcolC_1525 Escherichia coli ATCC 8739 zinc finger SWIM domain-containing protein YP_001724514.1 1683895 R 481805 CDS YP_001724515.1 170019561 6066616 complement(1687024..1689303) 1 NC_010468.1 KEGG: sfl:SF2189 hypothetical protein; hypothetical protein 1689303 6066616 EcolC_1528 Escherichia coli ATCC 8739 hypothetical protein YP_001724515.1 1687024 R 481805 CDS YP_001724516.1 170019562 6066532 complement(1689314..1690402) 1 NC_010468.1 PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sfx:S2313 hypothetical protein; ATPase 1690402 6066532 EcolC_1529 Escherichia coli ATCC 8739 ATPase YP_001724516.1 1689314 R 481805 CDS YP_001724517.1 170019563 6065917 complement(1690709..1691026) 1 NC_010468.1 KEGG: sfl:SF2187 hypothetical protein; hypothetical protein 1691026 6065917 EcolC_1530 Escherichia coli ATCC 8739 hypothetical protein YP_001724517.1 1690709 R 481805 CDS YP_001724518.1 170019564 6065902 complement(1691087..1694719) 1 NC_010468.1 KEGG: sbo:SBO_0938 putative regulator; putative regulator 1694719 6065902 EcolC_1531 Escherichia coli ATCC 8739 putative regulator YP_001724518.1 1691087 R 481805 CDS YP_001724519.1 170019565 6065895 complement(1694729..1698523) 1 NC_010468.1 PFAM: WGR domain protein; KEGG: sbo:SBO_0937 putative regulator (fragment); WGR domain-containing protein 1698523 6065895 EcolC_1532 Escherichia coli ATCC 8739 WGR domain-containing protein YP_001724519.1 1694729 R 481805 CDS YP_001724520.1 170019566 6065859 complement(1698664..1700697) 1 NC_010468.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1700697 metG 6065859 metG Escherichia coli ATCC 8739 methionyl-tRNA synthetase YP_001724520.1 1698664 R 481805 CDS YP_001724521.1 170019567 6065824 1700829..1701938 1 NC_010468.1 KEGG: sfv:SFV_2169 putative ATPase; putative ATPase 1701938 6065824 EcolC_1534 Escherichia coli ATCC 8739 putative ATPase YP_001724521.1 1700829 D 481805 CDS YP_001724522.1 170019568 6065802 1702201..1702482 1 NC_010468.1 KEGG: ssn:SSON_2161 hypothetical protein; hypothetical protein 1702482 6065802 EcolC_1535 Escherichia coli ATCC 8739 hypothetical protein YP_001724522.1 1702201 D 481805 CDS YP_001724523.1 170019569 6065805 1702775..1703317 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_2160 putative fimbrial-like protein; fimbrial protein 1703317 6065805 EcolC_1536 Escherichia coli ATCC 8739 fimbrial protein YP_001724523.1 1702775 D 481805 CDS YP_001724524.1 170019570 6065795 1703397..1704071 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_2159 putative chaperone; pili assembly chaperone 1704071 6065795 EcolC_1537 Escherichia coli ATCC 8739 pili assembly chaperone YP_001724524.1 1703397 D 481805 CDS YP_001724525.1 170019571 6065778 1704087..1706567 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfv:SFV_2164 putative outer membrane protein; fimbrial biogenesis outer membrane usher protein 1706567 6065778 EcolC_1538 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001724525.1 1704087 D 481805 CDS YP_001724526.1 170019572 6065749 1706583..1707617 1 NC_010468.1 KEGG: ssn:SSON_2156 putative type-1 fimbrial protein; putative type-1 fimbrial protein 1707617 6065749 EcolC_1539 Escherichia coli ATCC 8739 putative type-1 fimbrial protein YP_001724526.1 1706583 D 481805 CDS YP_001724527.1 170019573 6065716 complement(1707699..1708037) 1 NC_010468.1 KEGG: ssn:SSON_2155 hypothetical protein; hypothetical protein 1708037 6065716 EcolC_1540 Escherichia coli ATCC 8739 hypothetical protein YP_001724527.1 1707699 R 481805 CDS YP_001724528.1 170019574 6065685 complement(1708256..1709080) 1 NC_010468.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 1709080 6065685 EcolC_1541 Escherichia coli ATCC 8739 nickel/cobalt efflux protein RcnA YP_001724528.1 1708256 R 481805 CDS YP_001724529.1 170019575 6065636 1709201..1709473 1 NC_010468.1 PFAM: protein of unknown function DUF156; KEGG: sdy:SDY_2279 hypothetical protein; hypothetical protein 1709473 6065636 EcolC_1542 Escherichia coli ATCC 8739 hypothetical protein YP_001724529.1 1709201 D 481805 CDS YP_001724530.1 170019576 6065564 1709696..1710484 1 NC_010468.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 1710484 6065564 EcolC_1543 Escherichia coli ATCC 8739 hydroxyethylthiazole kinase YP_001724530.1 1709696 D 481805 CDS YP_001724531.1 170019577 6065473 1710481..1711281 1 NC_010468.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1711281 6065473 EcolC_1544 Escherichia coli ATCC 8739 phosphomethylpyrimidine kinase YP_001724531.1 1710481 D 481805 CDS YP_001724532.1 170019578 6065408 1711346..1712164 1 NC_010468.1 PFAM: glycoside hydrolase family 25; KEGG: sbo:SBO_0923 hypothetical protein; glycoside hydrolase family protein 1712164 6065408 EcolC_1545 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001724532.1 1711346 D 481805 CDS YP_001724533.1 170019579 6065407 1712216..1712962 1 NC_010468.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sdy:SDY_2274 putative transcriptional regulator; GntR family transcriptional regulator 1712962 6065407 EcolC_1546 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001724533.1 1712216 D 481805 CDS YP_001724534.1 170019580 6065385 complement(1713898..1714902) 1 NC_010468.1 PFAM: ADP-ribosylation/Crystallin J1; KEGG: ssn:SSON_2147 hypothetical protein; ADP-ribosylation/crystallin J1 1714902 6065385 EcolC_1548 Escherichia coli ATCC 8739 ADP-ribosylation/crystallin J1 YP_001724534.1 1713898 R 481805 CDS YP_001724535.1 170019581 6065367 complement(1714899..1716176) 1 NC_010468.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_2146 putative nucleoside permease protein; nucleoside transporter 1716176 6065367 EcolC_1549 Escherichia coli ATCC 8739 nucleoside transporter YP_001724535.1 1714899 R 481805 CDS YP_001724536.1 170019582 6065379 1716433..1717485 1 NC_010468.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 1717485 6065379 EcolC_1550 Escherichia coli ATCC 8739 fructose-bisphosphate aldolase YP_001724536.1 1716433 D 481805 CDS YP_001724537.1 170019583 6065355 1717793..1718647 1 NC_010468.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 1718647 gatY 6065355 gatY Escherichia coli ATCC 8739 tagatose-bisphosphate aldolase YP_001724537.1 1717793 D 481805 CDS YP_001724538.1 170019584 6065315 1718676..1719938 1 NC_010468.1 KEGG: sfv:SFV_2150 putative tagatose 6-phosphate kinase 1; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; D-tagatose-bisphosphate aldolase non-catalytic subunit 1719938 6065315 EcolC_1552 Escherichia coli ATCC 8739 D-tagatose-bisphosphate aldolase non-catalytic subunit YP_001724538.1 1718676 D 481805 CDS YP_001724539.1 170019585 6065296 1719948..1720400 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 1720400 6065296 EcolC_1553 Escherichia coli ATCC 8739 PTS system galactitol-specific transporter subunit IIA YP_001724539.1 1719948 D 481805 CDS YP_001724540.1 170019586 6065275 1720431..1720715 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 1720715 6065275 EcolC_1554 Escherichia coli ATCC 8739 PTS system galactitol-specific transporter subunit IIB YP_001724540.1 1720431 D 481805 CDS YP_001724541.1 170019587 6065268 1720719..1722074 1 NC_010468.1 TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: ssn:SSON_2139 PTS system galactitol-specific enzyme IIC; PTS system galactitol-specific transporter subunit IIC 1722074 6065268 EcolC_1555 Escherichia coli ATCC 8739 PTS system galactitol-specific transporter subunit IIC YP_001724541.1 1720719 D 481805 CDS YP_001724542.1 170019588 6067349 1722122..1723162 1 NC_010468.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 1723162 6067349 EcolC_1556 Escherichia coli ATCC 8739 galactitol-1-phosphate dehydrogenase YP_001724542.1 1722122 D 481805 CDS YP_001724543.1 170019589 6068255 1723268..1724041 1 NC_010468.1 PFAM: regulatory protein DeoR; KEGG: ssn:SSON_2137 galactitol utilization operon repressor; DeoR family transcriptional regulator 1724041 6068255 EcolC_1557 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001724543.1 1723268 D 481805 CDS YP_001724544.1 170019590 6067569 complement(1724123..1725022) 1 NC_010468.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 1725022 6067569 EcolC_1558 Escherichia coli ATCC 8739 lipid kinase YP_001724544.1 1724123 R 481805 CDS YP_001724545.1 170019591 6064436 1725428..1725745 1 NC_010468.1 KEGG: sbo:SBO_0909 hypothetical protein; hypothetical protein 1725745 6064436 EcolC_1559 Escherichia coli ATCC 8739 hypothetical protein YP_001724545.1 1725428 D 481805 CDS YP_001724546.1 170019592 6066531 complement(1726076..1727437) 1 NC_010468.1 PFAM: peptidase U32; KEGG: ssn:SSON_2134 hypothetical protein; peptidase U32 1727437 6066531 EcolC_1560 Escherichia coli ATCC 8739 peptidase U32 YP_001724546.1 1726076 R 481805 CDS YP_001724547.1 170019593 6066173 complement(1727584..1727916) 1 NC_010468.1 PFAM: protein of unknown function DUF1508; KEGG: sbo:SBO_0906 hypothetical protein; hypothetical protein 1727916 6066173 EcolC_1561 Escherichia coli ATCC 8739 hypothetical protein YP_001724547.1 1727584 R 481805 CDS YP_001724548.1 170019594 6065054 complement(1728107..1728829) 1 NC_010468.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 1728829 6065054 EcolC_1562 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator BaeR YP_001724548.1 1728107 R 481805 CDS YP_001724549.1 170019595 6065479 complement(1728826..1730229) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sfv:SFV_2139 sensor protein (for BaeR); signal transduction histidine-protein kinase BaeS 1730229 6065479 EcolC_1563 Escherichia coli ATCC 8739 signal transduction histidine-protein kinase BaeS YP_001724549.1 1728826 R 481805 CDS YP_001724550.1 170019596 6065361 complement(1730226..1731641) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S2267 putative transport protein; multidrug efflux system protein MdtE 1731641 6065361 EcolC_1564 Escherichia coli ATCC 8739 multidrug efflux system protein MdtE YP_001724550.1 1730226 R 481805 CDS YP_001724551.1 170019597 6067361 complement(1731642..1734719) 1 NC_010468.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 1734719 6067361 EcolC_1565 Escherichia coli ATCC 8739 multidrug efflux system subunit MdtC YP_001724551.1 1731642 R 481805 CDS YP_001724552.1 170019598 6066374 complement(1734720..1737842) 1 NC_010468.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 1737842 6066374 EcolC_1566 Escherichia coli ATCC 8739 multidrug efflux system subunit MdtB YP_001724552.1 1734720 R 481805 CDS YP_001724553.1 170019599 6065883 complement(1737842..1739209) 1 NC_010468.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 1739209 6065883 EcolC_1567 Escherichia coli ATCC 8739 multidrug efflux system subunit MdtA YP_001724553.1 1737842 R 481805 CDS YP_001724554.1 170019600 6065221 1739977..1740636 1 NC_010468.1 PFAM: von Willebrand factor type A; KEGG: sbo:SBO_0899 hypothetical protein; von Willebrand factor type A 1740636 6065221 EcolC_1568 Escherichia coli ATCC 8739 von Willebrand factor type A YP_001724554.1 1739977 D 481805 CDS YP_001724555.1 170019601 6066976 1740633..1741394 1 NC_010468.1 KEGG: ssn:SSON_2124 hypothetical protein; hypothetical protein 1741394 6066976 EcolC_1569 Escherichia coli ATCC 8739 hypothetical protein YP_001724555.1 1740633 D 481805 CDS YP_001724556.1 170019602 6065156 join(1741547..1741801,1741801..1742244) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 1742244 6065156 EcolC_1570 Escherichia coli ATCC 8739 insertion element protein YP_001724556.1 1741547 D 481805 CDS YP_001724557.1 170019603 6066550 1742271..1744178 1 NC_010468.1 KEGG: ssn:SSON_2123 putative chaperonin; putative chaperonin 1744178 6066550 EcolC_1571 Escherichia coli ATCC 8739 putative chaperonin YP_001724557.1 1742271 D 481805 CDS YP_001724558.1 170019604 6065691 complement(1744190..1745542) 1 NC_010468.1 KEGG: sbo:SBO_0896 putative heat shock protein; putative chaperone 1745542 6065691 EcolC_1572 Escherichia coli ATCC 8739 putative chaperone YP_001724558.1 1744190 R 481805 CDS YP_001724559.1 170019605 6066214 1745676..1746524 1 NC_010468.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 1746524 6066214 EcolC_1573 Escherichia coli ATCC 8739 3-methyladenine DNA glycosylase YP_001724559.1 1745676 D 481805 CDS YP_001724560.1 170019606 6065601 complement(1746633..1749950) 1 NC_010468.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 1749950 6065601 EcolC_1574 Escherichia coli ATCC 8739 putative sensor protein YP_001724560.1 1746633 R 481805 CDS YP_001724561.1 170019607 6066320 1750268..1750909 1 NC_010468.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1750909 6066320 EcolC_1575 Escherichia coli ATCC 8739 uridine kinase YP_001724561.1 1750268 D 481805 CDS YP_001724562.1 170019608 6066157 1751001..1751582 1 NC_010468.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1751582 dcd 6066157 dcd Escherichia coli ATCC 8739 deoxycytidine triphosphate deaminase YP_001724562.1 1751001 D 481805 CDS YP_001724563.1 170019609 6065405 1751604..1753457 1 NC_010468.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein 1753457 6065405 EcolC_1577 Escherichia coli ATCC 8739 putative assembly protein YP_001724563.1 1751604 D 481805 CDS YP_001724564.1 170019610 6065815 complement(1753731..1755314) 1 NC_010468.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: sfv:SFV_2122 putative transport protein; integral membrane protein TerC 1755314 6065815 EcolC_1578 Escherichia coli ATCC 8739 integral membrane protein TerC YP_001724564.1 1753731 R 481805 CDS YP_001724565.1 170019611 6067139 1755973..1757112 1 NC_010468.1 PFAM: polysaccharide export protein; KEGG: ssn:SSON_2115 putative polysaccharide export protein; polysaccharide export protein 1757112 6067139 EcolC_1579 Escherichia coli ATCC 8739 polysaccharide export protein YP_001724565.1 1755973 D 481805 CDS YP_001724566.1 170019612 6065125 1757118..1757561 1 NC_010468.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 1757561 6065125 EcolC_1580 Escherichia coli ATCC 8739 tyrosine phosphatase YP_001724566.1 1757118 D 481805 CDS YP_001724567.1 170019613 6064913 1757564..1759726 1 NC_010468.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 1759726 6064913 EcolC_1581 Escherichia coli ATCC 8739 tyrosine kinase YP_001724567.1 1757564 D 481805 CDS YP_001724568.1 170019614 6065990 1759819..1760658 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: sbo:SBO_0886 putative regulator; putative glycosyl transferase 1760658 6065990 EcolC_1582 Escherichia coli ATCC 8739 putative glycosyl transferase YP_001724568.1 1759819 D 481805 CDS YP_001724569.1 170019615 6066799 1760661..1761149 1 NC_010468.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB 1761149 6066799 EcolC_1583 Escherichia coli ATCC 8739 putative colanic acid biosynthesis acetyltransferase WcaB YP_001724569.1 1760661 D 481805 CDS YP_001724570.1 170019616 6066497 1761146..1762363 1 NC_010468.1 KEGG: sbo:SBO_0884 putative glycosyl transferase; putative glycosyl transferase 1762363 6066497 EcolC_1584 Escherichia coli ATCC 8739 putative glycosyl transferase YP_001724570.1 1761146 D 481805 CDS YP_001724571.1 170019617 6067031 1762338..1763555 1 NC_010468.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 1763555 wcaD 6067031 wcaD Escherichia coli ATCC 8739 putative colanic acid biosynthesis protein YP_001724571.1 1762338 D 481805 CDS YP_001724572.1 170019618 6066345 1763566..1764312 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_2108 putative colanic acid biosynthesis glycosyl transferase; putative glycosyl transferase 1764312 6066345 EcolC_1586 Escherichia coli ATCC 8739 putative glycosyl transferase YP_001724572.1 1763566 D 481805 CDS YP_001724573.1 170019619 6066314 1764453..1765001 1 NC_010468.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF 1765001 6066314 EcolC_1587 Escherichia coli ATCC 8739 putative colanic acid biosynthesis acetyltransferase WcaF YP_001724573.1 1764453 D 481805 CDS YP_001724574.1 170019620 6064971 1765027..1766148 1 NC_010468.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_0880 GDP-D-mannose dehydratase; GDP-mannose 4,6-dehydratase 1766148 6064971 EcolC_1588 Escherichia coli ATCC 8739 GDP-mannose 4,6-dehydratase YP_001724574.1 1765027 D 481805 CDS YP_001724575.1 170019621 6066811 1766151..1767116 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_0879 putative nucleotide di-P-sugar epimerase; NAD-dependent epimerase/dehydratase 1767116 6066811 EcolC_1589 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001724575.1 1766151 D 481805 CDS YP_001724576.1 170019622 6064796 1767119..1767598 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2108 GDP-mannose mannosyl hydrolase; NUDIX hydrolase 1767598 6064796 EcolC_1590 Escherichia coli ATCC 8739 NUDIX hydrolase YP_001724576.1 1767119 D 481805 CDS YP_001724577.1 170019623 6065933 1767595..1768818 1 NC_010468.1 PFAM: glycosyl transferase group 1; KEGG: sfx:S2236 putative colanic biosynthesis glycosyl transferase; putative glycosyl transferase 1768818 6065933 EcolC_1591 Escherichia coli ATCC 8739 putative glycosyl transferase YP_001724577.1 1767595 D 481805 CDS YP_001724578.1 170019624 6065291 1768821..1770257 1 NC_010468.1 KEGG: ssn:SSON_2102 mannose-1-phosphate guanyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1770257 6065291 EcolC_1592 Escherichia coli ATCC 8739 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_001724578.1 1768821 D 481805 CDS YP_001724579.1 170019625 6064652 1770450..1771820 1 NC_010468.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sbo:SBO_0875 phosphomannomutase; phosphomannomutase 1771820 6064652 EcolC_1593 Escherichia coli ATCC 8739 phosphomannomutase YP_001724579.1 1770450 D 481805 CDS YP_001724580.1 170019626 6065279 1771875..1773269 1 NC_010468.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase 1773269 6065279 EcolC_1594 Escherichia coli ATCC 8739 putative UDP-glucose lipid carrier transferase YP_001724580.1 1771875 D 481805 CDS YP_001724581.1 170019627 6065069 1773271..1774749 1 NC_010468.1 PFAM: polysaccharide biosynthesis protein; KEGG: sbo:SBO_0873 probable export protein; colanic acid exporter 1774749 6065069 EcolC_1595 Escherichia coli ATCC 8739 colanic acid exporter YP_001724581.1 1773271 D 481805 CDS YP_001724582.1 170019628 6064689 1775025..1776305 1 NC_010468.1 PFAM: polysaccharide pyruvyl transferase; KEGG: sbo:SBO_0872 putative galactokinase; putative pyruvyl transferase 1776305 6064689 EcolC_1596 Escherichia coli ATCC 8739 putative pyruvyl transferase YP_001724582.1 1775025 D 481805 CDS YP_001724583.1 170019629 6065495 1776302..1777522 1 NC_010468.1 PFAM: glycosyl transferase group 1; KEGG: sbo:SBO_0871 putative colanic acid biosynthesis glycosyl transferase; group 1 glycosyl transferase 1777522 6065495 EcolC_1597 Escherichia coli ATCC 8739 group 1 glycosyl transferase YP_001724583.1 1776302 D 481805 CDS YP_001724584.1 170019630 6065621 1777533..1778927 1 NC_010468.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein 1778927 wcaM 6065621 wcaM Escherichia coli ATCC 8739 putative colanic acid biosynthesis protein YP_001724584.1 1777533 D 481805 CDS YP_001724585.1 170019631 6066057 1779085..1780080 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: esa:ESA_01176 hypothetical protein; NAD-dependent epimerase/dehydratase 1780080 6066057 EcolC_1599 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001724585.1 1779085 D 481805 CDS YP_001724586.1 170019632 6066055 1780323..1781216 1 NC_010468.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 1781216 6066055 EcolC_1600 Escherichia coli ATCC 8739 UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_001724586.1 1780323 D 481805 CDS YP_001724587.1 170019633 6066255 1781588..1782673 1 NC_010468.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase 1782673 6066255 EcolC_1601 Escherichia coli ATCC 8739 dTDP-glucose-4,6-dehydratase YP_001724587.1 1781588 D 481805 CDS YP_001724588.1 170019634 6064868 1782673..1783572 1 NC_010468.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 1783572 6064868 EcolC_1602 Escherichia coli ATCC 8739 dTDP-4-dehydrorhamnose reductase YP_001724588.1 1782673 D 481805 CDS YP_001724589.1 170019635 6065198 1783630..1784508 1 NC_010468.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sbo:SBO_0866 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 1784508 6065198 EcolC_1603 Escherichia coli ATCC 8739 glucose-1-phosphate thymidylyltransferase YP_001724589.1 1783630 D 481805 CDS YP_001724590.1 170019636 6065233 1784513..1785046 1 NC_010468.1 KEGG: sdy:SDY_2207 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 1785046 6065233 EcolC_1604 Escherichia coli ATCC 8739 dTDP-4-dehydrorhamnose 3,5-epimerase YP_001724590.1 1784513 D 481805 CDS YP_001724591.1 170019637 6066186 1785061..1786053 1 NC_010468.1 PFAM: nitroreductase; KEGG: mpt:Mpe_A0731 nitroreductase-like protein; nitroreductase 1786053 6066186 EcolC_1605 Escherichia coli ATCC 8739 nitroreductase YP_001724591.1 1785061 D 481805 CDS YP_001724592.1 170019638 6065231 1786050..1787588 1 NC_010468.1 KEGG: bfs:BF2791 putative transmembrane protein; putative transmembrane protein 1787588 6065231 EcolC_1606 Escherichia coli ATCC 8739 putative transmembrane protein YP_001724592.1 1786050 D 481805 CDS YP_001724593.1 170019639 6066178 1787581..1788684 1 NC_010468.1 KEGG: bfs:BF2794 hypothetical protein; hypothetical protein 1788684 6066178 EcolC_1607 Escherichia coli ATCC 8739 hypothetical protein YP_001724593.1 1787581 D 481805 CDS YP_001724594.1 170019640 6067678 1788690..1789832 1 NC_010468.1 PFAM: glycosyl transferase group 1; KEGG: lsl:LSL_0978 glycosyltransferase; group 1 glycosyl transferase 1789832 6067678 EcolC_1608 Escherichia coli ATCC 8739 group 1 glycosyl transferase YP_001724594.1 1788690 D 481805 CDS YP_001724595.1 170019641 6065241 1789894..1791129 1 NC_010468.1 KEGG: ssp:SSP0069 putative polysaccharide polymerase; hypothetical protein 1791129 6065241 EcolC_1609 Escherichia coli ATCC 8739 hypothetical protein YP_001724595.1 1789894 D 481805 CDS YP_001724596.1 170019642 6065121 1791092..1791979 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: pat:Patl_3205 rhamnosyltransferase; glycosyl transferase family protein 1791979 6065121 EcolC_1610 Escherichia coli ATCC 8739 glycosyl transferase family protein YP_001724596.1 1791092 D 481805 CDS YP_001724597.1 170019643 6065827 complement(join(1792279..1792722,1792722..1792976)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein; insertion element protein 1792976 6065827 EcolC_1612 Escherichia coli ATCC 8739 insertion element protein YP_001724597.1 1792279 R 481805 CDS YP_001724598.1 170019644 6067000 1794104..1795510 1 NC_010468.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1795510 6067000 EcolC_1613 Escherichia coli ATCC 8739 6-phosphogluconate dehydrogenase YP_001724598.1 1794104 D 481805 CDS YP_001724599.1 170019645 6065807 1795759..1796925 1 NC_010468.1 KEGG: ssn:SSON_2099 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; nucleotide sugar dehydrogenase 1796925 6065807 EcolC_1614 Escherichia coli ATCC 8739 nucleotide sugar dehydrogenase YP_001724599.1 1795759 D 481805 CDS YP_001724600.1 170019646 6066608 1797072..1798052 1 NC_010468.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: ssn:SSON_2098 regulator of length of O-antigen component of lipopolysaccharide chains; lipopolysaccharide biosynthesis protein 1798052 6066608 EcolC_1615 Escherichia coli ATCC 8739 lipopolysaccharide biosynthesis protein YP_001724600.1 1797072 D 481805 CDS YP_001724601.1 170019647 6067233 complement(1798149..1798760) 1 NC_010468.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1798760 6067233 EcolC_1616 Escherichia coli ATCC 8739 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_001724601.1 1798149 R 481805 CDS YP_001724602.1 170019648 6065359 complement(1798754..1799530) 1 NC_010468.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1799530 6065359 EcolC_1617 Escherichia coli ATCC 8739 imidazole glycerol phosphate synthase subunit HisF YP_001724602.1 1798754 R 481805 CDS YP_001724603.1 170019649 6066541 complement(1799512..1800249) 1 NC_010468.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1800249 6066541 EcolC_1618 Escherichia coli ATCC 8739 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_001724603.1 1799512 R 481805 CDS YP_001724604.1 170019650 6066676 complement(1800249..1800839) 1 NC_010468.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1800839 hisH 6066676 hisH Escherichia coli ATCC 8739 imidazole glycerol phosphate synthase subunit HisH YP_001724604.1 1800249 R 481805 CDS YP_001724605.1 170019651 6066075 complement(1800839..1801906) 1 NC_010468.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1801906 6066075 EcolC_1620 Escherichia coli ATCC 8739 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_001724605.1 1800839 R 481805 CDS YP_001724606.1 170019652 6066776 complement(1801906..1802976) 1 NC_010468.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1802976 6066776 EcolC_1621 Escherichia coli ATCC 8739 histidinol-phosphate aminotransferase YP_001724606.1 1801906 R 481805 CDS YP_001724607.1 170019653 6066383 complement(1802973..1804277) 1 NC_010468.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1804277 hisD 6066383 hisD Escherichia coli ATCC 8739 histidinol dehydrogenase YP_001724607.1 1802973 R 481805 CDS YP_001724608.1 170019654 6065987 complement(1804283..1805182) 1 NC_010468.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1805182 hisG 6065987 hisG Escherichia coli ATCC 8739 ATP phosphoribosyltransferase YP_001724608.1 1804283 R 481805 CDS YP_001724609.1 170019655 6064968 1805803..1806627 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ssn:SSON_2086 putative enzyme of sugar metabolism; NAD-dependent epimerase/dehydratase 1806627 6064968 EcolC_1624 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001724609.1 1805803 D 481805 CDS YP_001724610.1 170019656 6065880 1806673..1807602 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_0841 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 1807602 6065880 EcolC_1625 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001724610.1 1806673 D 481805 CDS YP_001724611.1 170019657 6066151 1807869..1809227 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2226 putative amino acid/amine transport protein; amino acid permease-associated protein 1809227 6066151 EcolC_1626 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001724611.1 1807869 D 481805 CDS YP_001724612.1 170019658 6065324 1809406..1810464 1 NC_010468.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: ssn:SSON_2083 putative transport system permease protein; hypothetical protein 1810464 6065324 EcolC_1627 Escherichia coli ATCC 8739 hypothetical protein YP_001724612.1 1809406 D 481805 CDS YP_001724613.1 170019659 6065793 1810478..1810705 1 NC_010468.1 PFAM: SirA family protein; KEGG: sbo:SBO_0836 hypothetical protein; SirA family protein 1810705 6065793 EcolC_1628 Escherichia coli ATCC 8739 SirA family protein YP_001724613.1 1810478 D 481805 CDS YP_001724614.1 170019660 6066380 complement(1810748..1812175) 1 NC_010468.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1812175 sbcB 6066380 sbcB Escherichia coli ATCC 8739 exonuclease I YP_001724614.1 1810748 R 481805 CDS YP_001724615.1 170019661 6064760 1812384..1813550 1 NC_010468.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1813550 dacD 6064760 dacD Escherichia coli ATCC 8739 D-alanyl-D-alanine carboxypeptidase YP_001724615.1 1812384 D 481805 CDS YP_001724616.1 170019662 6067104 1813669..1814142 1 NC_010468.1 PFAM: transcription activator effector binding; KEGG: ssn:SSON_2079 SbmC protein; DNA gyrase inhibitor 1814142 6067104 EcolC_1631 Escherichia coli ATCC 8739 DNA gyrase inhibitor YP_001724616.1 1813669 D 481805 CDS YP_001724617.1 170019663 6065734 1814341..1815399 1 NC_010468.1 KEGG: ssn:SSON_2078 hypothetical protein; hypothetical protein 1815399 6065734 EcolC_1632 Escherichia coli ATCC 8739 hypothetical protein YP_001724617.1 1814341 D 481805 CDS YP_001724618.1 170019664 6066428 1815571..1815900 1 NC_010468.1 PFAM: protein of unknown function DUF496; KEGG: sbo:SBO_0832 putative alpha helix protein; hypothetical protein 1815900 6066428 EcolC_1633 Escherichia coli ATCC 8739 hypothetical protein YP_001724618.1 1815571 D 481805 CDS YP_001724619.1 170019665 6065129 1816359..1816904 1 NC_010468.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1816904 cobU 6065129 cobU Escherichia coli ATCC 8739 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_001724619.1 1816359 D 481805 CDS YP_001724620.1 170019666 6065626 1816901..1817644 1 NC_010468.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1817644 cobS 6065626 cobS Escherichia coli ATCC 8739 cobalamin synthase YP_001724620.1 1816901 D 481805 CDS YP_001724621.1 170019667 6066240 1817656..1818735 1 NC_010468.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1818735 cobT 6066240 cobT Escherichia coli ATCC 8739 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_001724621.1 1817656 D 481805 CDS YP_001724622.1 170019668 6065643 1818800..1819723 1 NC_010468.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2243 hypothetical protein; hypothetical protein 1819723 6065643 EcolC_1638 Escherichia coli ATCC 8739 hypothetical protein YP_001724622.1 1818800 D 481805 CDS YP_001724623.1 170019669 6065580 1819885..1820862 1 NC_010468.1 PFAM: putative sugar-binding domain protein; KEGG: sco:SCO1463 putative transcriptional regulator; DeoR family transcriptional regulator 1820862 6065580 EcolC_1639 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001724623.1 1819885 D 481805 CDS YP_001724624.1 170019670 6066471 complement(1820914..1821372) 1 NC_010468.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: lca:LSEI_2707 phosphotransferase system galactitol-specific IIA domain (Ntr-type); putative PTS IIA-like nitrogen-regulatory protein PtsN 1821372 6066471 EcolC_1640 Escherichia coli ATCC 8739 putative PTS IIA-like nitrogen-regulatory protein PtsN YP_001724624.1 1820914 R 481805 CDS YP_001724625.1 170019671 6066803 complement(1821383..1821667) 1 NC_010468.1 KEGG: sak:SAK_0530 PTS system, galactitol-specific IIB component, putative; PTS system galactitol-specific transporter subunit IIB 1821667 6066803 EcolC_1641 Escherichia coli ATCC 8739 PTS system galactitol-specific transporter subunit IIB YP_001724625.1 1821383 R 481805 CDS YP_001724626.1 170019672 6064683 complement(1821691..1823061) 1 NC_010468.1 PFAM: PTS system Galactitol-specific IIC component; KEGG: tte:TTE0183 PTS system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1823061 6064683 EcolC_1642 Escherichia coli ATCC 8739 PTS system galactitol-specific transporter subunit IIC YP_001724626.1 1821691 R 481805 CDS YP_001724627.1 170019673 6066584 complement(1823065..1823601) 1 NC_010468.1 TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: aae:aq_1138 ribose 5-phosphate isomerase B; RpiB/LacA/LacB family sugar-phosphate isomerase 1823601 6066584 EcolC_1643 Escherichia coli ATCC 8739 RpiB/LacA/LacB family sugar-phosphate isomerase YP_001724627.1 1823065 R 481805 CDS YP_001724628.1 170019674 6065120 1823950..1824705 1 NC_010468.1 PFAM: regulatory protein DeoR; KEGG: bcl:ABC3573 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 1824705 6065120 EcolC_1644 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001724628.1 1823950 D 481805 CDS YP_001724629.1 170019675 6065115 1825033..1825476 1 NC_010468.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: hso:HS_1144 PTS system, galactitol-specific IIA component; putative PTS IIA-like nitrogen-regulatory protein PtsN 1825476 6065115 EcolC_1645 Escherichia coli ATCC 8739 putative PTS IIA-like nitrogen-regulatory protein PtsN YP_001724629.1 1825033 D 481805 CDS YP_001724630.1 170019676 6067185 1825495..1825788 1 NC_010468.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: cdf:CD1083 PTS system, IIb component; PTS system lactose/cellobiose-specific transporter subunit IIB 1825788 6067185 EcolC_1646 Escherichia coli ATCC 8739 PTS system lactose/cellobiose-specific transporter subunit IIB YP_001724630.1 1825495 D 481805 CDS YP_001724631.1 170019677 6065248 1825809..1827062 1 NC_010468.1 PFAM: PTS system Galactitol-specific IIC component; KEGG: pac:PPA0022 PTS system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1827062 6065248 EcolC_1647 Escherichia coli ATCC 8739 PTS system galactitol-specific transporter subunit IIC YP_001724631.1 1825809 D 481805 CDS YP_001724632.1 170019678 6064848 1827085..1827729 1 NC_010468.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: lmf:LMOf2365_0534 ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 1827729 6064848 EcolC_1648 Escherichia coli ATCC 8739 ribulose-phosphate 3-epimerase YP_001724632.1 1827085 D 481805 CDS YP_001724633.1 170019679 6064845 1827827..1828579 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpu:BPUM_1176 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 1828579 6064845 EcolC_1649 Escherichia coli ATCC 8739 short-chain dehydrogenase/reductase SDR YP_001724633.1 1827827 D 481805 CDS YP_001724634.1 170019680 6066009 1828595..1829155 1 NC_010468.1 PFAM: sugar isomerase (SIS); KEGG: bsu:BG11182 6-phospho-3-hexuloisomerase; sugar isomerase (SIS) 1829155 6066009 EcolC_1650 Escherichia coli ATCC 8739 sugar isomerase (SIS) YP_001724634.1 1828595 D 481805 CDS YP_001724635.1 170019681 6065588 1829696..1833679 1 NC_010468.1 hypothetical protein 1833679 6065588 EcolC_1651 Escherichia coli ATCC 8739 hypothetical protein YP_001724635.1 1829696 D 481805 CDS YP_001724636.1 170019682 6066336 1833672..1835798 1 NC_010468.1 KEGG: plu:plu0532 hypothetical protein; hypothetical protein 1835798 6066336 EcolC_1652 Escherichia coli ATCC 8739 hypothetical protein YP_001724636.1 1833672 D 481805 CDS YP_001724637.1 170019683 6066987 complement(1836693..1840448) 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 1840448 6066987 EcolC_1653 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001724637.1 1836693 R 481805 CDS YP_001724638.1 170019684 6067356 1840904..1841419 1 NC_010468.1 KEGG: sbo:SBO_1138 hypothetical protein; hypothetical protein 1841419 6067356 EcolC_1654 Escherichia coli ATCC 8739 hypothetical protein YP_001724638.1 1840904 D 481805 CDS YP_001724639.1 170019685 6065074 1842326..1843210 1 NC_010468.1 KEGG: ypk:y3085 hypothetical protein; hypothetical protein 1843210 6065074 EcolC_1655 Escherichia coli ATCC 8739 hypothetical protein YP_001724639.1 1842326 D 481805 CDS YP_001724640.1 170019686 6067292 1846408..1847325 1 NC_010468.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 1847325 6067292 EcolC_1657 Escherichia coli ATCC 8739 nitrogen assimilation transcriptional regulator YP_001724640.1 1846408 D 481805 CDS YP_001724641.1 170019687 6067564 1847427..1848377 1 NC_010468.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 1848377 cbl 6067564 cbl Escherichia coli ATCC 8739 transcriptional regulator Cbl YP_001724641.1 1847427 D 481805 CDS YP_001724642.1 170019688 6067098 1848651..1850138 1 NC_010468.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ssn:SSON_2044 hypothetical protein; hypothetical protein 1850138 6067098 EcolC_1659 Escherichia coli ATCC 8739 hypothetical protein YP_001724642.1 1848651 D 481805 CDS YP_001724643.1 170019689 6066477 complement(1850767..1851483) 1 NC_010468.1 PFAM: protein of unknown function DUF28; KEGG: sbo:SBO_1217 hypothetical protein; hypothetical protein 1851483 6066477 EcolC_1660 Escherichia coli ATCC 8739 hypothetical protein YP_001724643.1 1850767 R 481805 CDS YP_001724644.1 170019690 6064801 complement(1851826..1853280) 1 NC_010468.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 1853280 6064801 EcolC_1661 Escherichia coli ATCC 8739 AMP nucleosidase YP_001724644.1 1851826 R 481805 CDS YP_001724645.1 170019691 6064800 complement(1853382..1854698) 1 NC_010468.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2254 putative transport protein, shikimate; shikimate transporter 1854698 6064800 EcolC_1662 Escherichia coli ATCC 8739 shikimate transporter YP_001724645.1 1853382 R 481805 CDS YP_001724646.1 170019692 6065698 1855013..1856065 1 NC_010468.1 KEGG: ssn:SSON_2040 hypothetical protein; ADP-heptose--LPS heptosyltransferase-like protein 1856065 6065698 EcolC_1663 Escherichia coli ATCC 8739 ADP-heptose--LPS heptosyltransferase-like protein YP_001724646.1 1855013 D 481805 CDS YP_001724647.1 170019693 6065112 complement(1864425..1868024) 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 1868024 6065112 EcolC_1667 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001724647.1 1864425 R 481805 CDS YP_001724648.1 170019694 6066067 1868927..1869811 1 NC_010468.1 KEGG: ypk:y3085 hypothetical protein; hypothetical protein 1869811 6066067 EcolC_1668 Escherichia coli ATCC 8739 hypothetical protein YP_001724648.1 1868927 D 481805 CDS YP_001724649.1 170019695 6064685 complement(1872721..1873518) 1 NC_010468.1 PFAM: protein of unknown function DUF980; KEGG: ssn:SSON_2035 hypothetical protein; hypothetical protein 1873518 6064685 EcolC_1670 Escherichia coli ATCC 8739 hypothetical protein YP_001724649.1 1872721 R 481805 CDS YP_001724650.1 170019696 6066686 complement(1874271..1874801) 1 NC_010468.1 PFAM: cytochrome B561; KEGG: sbo:SBO_1032 putative cytochrome; cytochrome B561 1874801 6066686 EcolC_1671 Escherichia coli ATCC 8739 cytochrome B561 YP_001724650.1 1874271 R 481805 CDS YP_001724651.1 170019697 6066765 complement(1875144..1875815) 1 NC_010468.1 PFAM: YodA domain protein; KEGG: sdy:SDY_1033 hypothetical protein; hypothetical protein 1875815 6066765 EcolC_1672 Escherichia coli ATCC 8739 hypothetical protein YP_001724651.1 1875144 R 481805 CDS YP_001724652.1 170019698 6066431 complement(1876051..1876686) 1 NC_010468.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 1876686 6066431 EcolC_1673 Escherichia coli ATCC 8739 putative sulfite oxidase subunit YedZ YP_001724652.1 1876051 R 481805 CDS YP_001724653.1 170019699 6065742 complement(1876687..1877691) 1 NC_010468.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 1877691 6065742 EcolC_1674 Escherichia coli ATCC 8739 putative sulfite oxidase subunit YedY YP_001724653.1 1876687 R 481805 CDS YP_001724654.1 170019700 6066042 complement(1877800..1878213) 1 NC_010468.1 TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: sfv:SFV_2015 hypothetical protein; hydroxyisourate hydrolase 1878213 6066042 EcolC_1675 Escherichia coli ATCC 8739 hydroxyisourate hydrolase YP_001724654.1 1877800 R 481805 CDS YP_001724655.1 170019701 6065461 1878235..1879017 1 NC_010468.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 1879017 6065461 EcolC_1676 Escherichia coli ATCC 8739 transcriptional regulatory protein YedW YP_001724655.1 1878235 D 481805 CDS YP_001724656.1 170019702 6066865 1879017..1880375 1 NC_010468.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_2026 putative 2-component sensor protein; heavy metal sensor signal transduction histidine kinase 1880375 6066865 EcolC_1677 Escherichia coli ATCC 8739 heavy metal sensor signal transduction histidine kinase YP_001724656.1 1879017 D 481805 CDS YP_001724657.1 170019703 6066273 complement(1880483..1881334) 1 NC_010468.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 1881334 6066273 EcolC_1678 Escherichia coli ATCC 8739 chaperone protein HchA YP_001724657.1 1880483 R 481805 CDS YP_001724658.1 170019704 6064939 complement(1881927..1883000) 1 NC_010468.1 PFAM: porin Gram-negative type; KEGG: spe:Spro_1730 porin gram-negative type; porin 1883000 6064939 EcolC_1679 Escherichia coli ATCC 8739 porin YP_001724658.1 1881927 R 481805 CDS YP_001724659.1 170019705 6065649 1883549..1883932 1 NC_010468.1 KEGG: sbo:SBO_1045 hypothetical protein; hypothetical protein 1883932 6065649 EcolC_1680 Escherichia coli ATCC 8739 hypothetical protein YP_001724659.1 1883549 D 481805 CDS YP_001724660.1 170019706 6065958 1883972..1884667 1 NC_010468.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbo:SBO_1046 hypothetical protein; hypothetical protein 1884667 6065958 EcolC_1681 Escherichia coli ATCC 8739 hypothetical protein YP_001724660.1 1883972 D 481805 CDS YP_001724661.1 170019707 6066519 1884734..1886152 1 NC_010468.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ssn:SSON_2018 DNA cytosine methylase; DNA cytosine methylase 1886152 6066519 EcolC_1682 Escherichia coli ATCC 8739 DNA cytosine methylase YP_001724661.1 1884734 D 481805 CDS YP_001724662.1 170019708 6064609 1886133..1886603 1 NC_010468.1 TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: sdy:SDY_1046 DNA mismatch endonuclease, patch repair protein; DNA mismatch endonuclease Vsr 1886603 6064609 EcolC_1683 Escherichia coli ATCC 8739 DNA mismatch endonuclease Vsr YP_001724662.1 1886133 D 481805 CDS YP_001724663.1 170019709 6066642 complement(1886592..1887512) 1 NC_010468.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_1049 putative transmembrane subunit; hypothetical protein 1887512 6066642 EcolC_1684 Escherichia coli ATCC 8739 hypothetical protein YP_001724663.1 1886592 R 481805 CDS YP_001724664.1 170019710 6065428 1887685..1888602 1 NC_010468.1 PFAM: protein of unknown function DUF808; KEGG: sdy:SDY_1048 hypothetical protein; hypothetical protein 1888602 6065428 EcolC_1685 Escherichia coli ATCC 8739 hypothetical protein YP_001724664.1 1887685 D 481805 CDS YP_001724665.1 170019711 6066448 1888681..1888863 1 NC_010468.1 KEGG: sdy:SDY_1049 hypothetical protein; hypothetical protein 1888863 6066448 EcolC_1686 Escherichia coli ATCC 8739 hypothetical protein YP_001724665.1 1888681 D 481805 CDS YP_001724666.1 170019712 6065583 1889101..1890795 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_2013 hypothetical protein; diguanylate cyclase 1890795 6065583 EcolC_1687 Escherichia coli ATCC 8739 diguanylate cyclase YP_001724666.1 1889101 D 481805 CDS YP_001724667.1 170019713 6066364 complement(1890792..1891607) 1 NC_010468.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1891607 6066364 EcolC_1688 Escherichia coli ATCC 8739 mannosyl-3-phosphoglycerate phosphatase YP_001724667.1 1890792 R 481805 CDS YP_001724668.1 170019714 6064869 complement(1891905..1892132) 1 NC_010468.1 KEGG: sdy:SDY_1052 hypothetical protein; hypothetical protein 1892132 6064869 EcolC_1689 Escherichia coli ATCC 8739 hypothetical protein YP_001724668.1 1891905 R 481805 CDS YP_001724669.1 170019715 6065955 1892295..1892483 1 NC_010468.1 KEGG: sdy:SDY_1053 hypothetical protein; hypothetical protein 1892483 6065955 EcolC_1690 Escherichia coli ATCC 8739 hypothetical protein YP_001724669.1 1892295 D 481805 CDS YP_001724670.1 170019716 6064920 complement(1892527..1893150) 1 NC_010468.1 PFAM: regulatory protein LuxR; KEGG: sbo:SBO_1056 positive regulator for ctr capsule biosynthesis, positive transcription factor; LuxR family transcriptional regulator 1893150 6064920 EcolC_1691 Escherichia coli ATCC 8739 LuxR family transcriptional regulator YP_001724670.1 1892527 R 481805 CDS YP_001724671.1 170019717 6065259 complement(1893440..1894225) 1 NC_010468.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1894225 fliR 6065259 fliR Escherichia coli ATCC 8739 flagellar biosynthesis protein FliR YP_001724671.1 1893440 R 481805 CDS YP_001724672.1 170019718 6065545 complement(1894234..1894503) 1 NC_010468.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1894503 fliQ 6065545 fliQ Escherichia coli ATCC 8739 flagellar biosynthesis protein FliQ YP_001724672.1 1894234 R 481805 CDS YP_001724673.1 170019719 6066908 complement(1894513..1895250) 1 NC_010468.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1895250 fliP 6066908 fliP Escherichia coli ATCC 8739 flagellar biosynthesis protein FliP YP_001724673.1 1894513 R 481805 CDS YP_001724674.1 170019720 6065692 complement(1895250..1895615) 1 NC_010468.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 1895615 6065692 EcolC_1695 Escherichia coli ATCC 8739 flagellar biosynthesis protein FliO YP_001724674.1 1895250 R 481805 CDS YP_001724675.1 170019721 6066071 complement(1895618..1896031) 1 NC_010468.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1896031 fliN 6066071 fliN Escherichia coli ATCC 8739 flagellar motor switch protein FliN YP_001724675.1 1895618 R 481805 CDS YP_001724676.1 170019722 6064611 complement(1896028..1897032) 1 NC_010468.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1897032 fliM 6064611 fliM Escherichia coli ATCC 8739 flagellar motor switch protein FliM YP_001724676.1 1896028 R 481805 CDS YP_001724677.1 170019723 6066719 complement(1897037..1897501) 1 NC_010468.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 1897501 fliL 6066719 fliL Escherichia coli ATCC 8739 flagellar basal body-associated protein FliL YP_001724677.1 1897037 R 481805 CDS YP_001724678.1 170019724 6066712 complement(1897606..1898733) 1 NC_010468.1 PFAM: flagellar hook-length control protein; KEGG: sfv:SFV_1986 flagellar hook-length control protein; flagellar hook-length control protein 1898733 6066712 EcolC_1699 Escherichia coli ATCC 8739 flagellar hook-length control protein YP_001724678.1 1897606 R 481805 CDS YP_001724679.1 170019725 6065422 complement(1898730..1899173) 1 NC_010468.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 1899173 fliJ 6065422 fliJ Escherichia coli ATCC 8739 flagellar biosynthesis chaperone YP_001724679.1 1898730 R 481805 CDS YP_001724680.1 170019726 6065421 complement(1899192..1900565) 1 NC_010468.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1900565 fliI 6065421 fliI Escherichia coli ATCC 8739 flagellum-specific ATP synthase YP_001724680.1 1899192 R 481805 CDS YP_001724681.1 170019727 6066728 complement(1900565..1901251) 1 NC_010468.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1901251 fliH 6066728 fliH Escherichia coli ATCC 8739 flagellar assembly protein H YP_001724681.1 1900565 R 481805 CDS YP_001724682.1 170019728 6064630 complement(1901244..1902239) 1 NC_010468.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1902239 fliG 6064630 fliG Escherichia coli ATCC 8739 flagellar motor switch protein G YP_001724682.1 1901244 R 481805 CDS YP_001724683.1 170019729 6064603 complement(1902232..1903890) 1 NC_010468.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1903890 fliF 6064603 fliF Escherichia coli ATCC 8739 flagellar MS-ring protein YP_001724683.1 1902232 R 481805 CDS YP_001724684.1 170019730 6065308 1904105..1904419 1 NC_010468.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1904419 fliE 6065308 fliE Escherichia coli ATCC 8739 flagellar hook-basal body protein FliE YP_001724684.1 1904105 D 481805 CDS YP_001724685.1 170019731 6066853 complement(1905980..1906651) 1 NC_010468.1 PFAM: protein of unknown function DUF159; KEGG: sdy:SDY_1084 hypothetical protein; hypothetical protein 1906651 6066853 EcolC_1708 Escherichia coli ATCC 8739 hypothetical protein YP_001724685.1 1905980 R 481805 CDS YP_001724686.1 170019732 6065451 complement(1906758..1906991) 1 NC_010468.1 PFAM: SirA family protein; KEGG: cko:CKO_01008 hypothetical protein; hypothetical protein 1906991 6065451 EcolC_1709 Escherichia coli ATCC 8739 hypothetical protein YP_001724686.1 1906758 R 481805 CDS YP_001724687.1 170019733 6065338 complement(1906988..1908193) 1 NC_010468.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: sbo:SBO_1077 putative transport system permease protein; putative inner membrane protein 1908193 6065338 EcolC_1710 Escherichia coli ATCC 8739 putative inner membrane protein YP_001724687.1 1906988 R 481805 CDS YP_001724688.1 170019734 6067465 1908380..1908793 1 NC_010468.1 KEGG: sdy:SDY_1087 hypothetical protein; hypothetical protein 1908793 6067465 EcolC_1711 Escherichia coli ATCC 8739 hypothetical protein YP_001724688.1 1908380 D 481805 CDS YP_001724689.1 170019735 6066299 complement(1908827..1910314) 1 NC_010468.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1910314 6066299 EcolC_1712 Escherichia coli ATCC 8739 alpha-amylase YP_001724689.1 1908827 R 481805 CDS YP_001724690.1 170019736 6065840 complement(1910392..1910757) 1 NC_010468.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 1910757 6065840 EcolC_1713 Escherichia coli ATCC 8739 flagellar biosynthesis protein FliT YP_001724690.1 1910392 R 481805 CDS YP_001724691.1 170019737 6066437 complement(1910757..1911167) 1 NC_010468.1 flagellin specific chaperone; flagellar protein FliS 1911167 fliS 6066437 fliS Escherichia coli ATCC 8739 flagellar protein FliS YP_001724691.1 1910757 R 481805 CDS YP_001724692.1 170019738 6067457 complement(1911192..1912598) 1 NC_010468.1 involved in flagellin assembly; flagellar capping protein 1912598 fliD 6067457 fliD Escherichia coli ATCC 8739 flagellar capping protein YP_001724692.1 1911192 R 481805 CDS YP_001724693.1 170019739 6065051 1912864..1914582 1 NC_010468.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 1914582 6065051 EcolC_1716 Escherichia coli ATCC 8739 flagellin YP_001724693.1 1912864 D 481805 CDS YP_001724694.1 170019740 6066652 1914902..1915621 1 NC_010468.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1915621 fliA 6066652 fliA Escherichia coli ATCC 8739 flagellar biosynthesis sigma factor YP_001724694.1 1914902 D 481805 CDS YP_001724695.1 170019741 6067320 1915667..1916218 1 NC_010468.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1916218 6067320 EcolC_1718 Escherichia coli ATCC 8739 flagella biosynthesis protein FliZ YP_001724695.1 1915667 D 481805 CDS YP_001724696.1 170019742 6065148 1916249..1917106 1 NC_010468.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: sfl:SF1963 putative periplasmic binding transport protein; cystine transporter subunit 1917106 6065148 EcolC_1719 Escherichia coli ATCC 8739 cystine transporter subunit YP_001724696.1 1916249 D 481805 CDS YP_001724697.1 170019743 6067313 1917211..1918197 1 NC_010468.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1918197 6067313 EcolC_1720 Escherichia coli ATCC 8739 D-cysteine desulfhydrase YP_001724697.1 1917211 D 481805 CDS YP_001724698.1 170019744 6066856 1918212..1918880 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1200 putative transport system permease protein (former YecC); polar amino acid ABC transporter inner membrane protein 1918880 6066856 EcolC_1721 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001724698.1 1918212 D 481805 CDS YP_001724699.1 170019745 6067496 1918877..1919629 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_1201 putative ATP-binding component of a transport system; putative amino-acid ABC transporter ATP-binding protein YecC 1919629 6067496 EcolC_1722 Escherichia coli ATCC 8739 putative amino-acid ABC transporter ATP-binding protein YecC YP_001724699.1 1918877 D 481805 CDS YP_001724700.1 170019746 6066493 1919859..1920581 1 NC_010468.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 1920581 6066493 EcolC_1723 Escherichia coli ATCC 8739 DNA-binding transcriptional activator SdiA YP_001724700.1 1919859 D 481805 CDS YP_001724701.1 170019747 6065297 complement(1920649..1920873) 1 NC_010468.1 KEGG: sdy:SDY_1103 hypothetical protein; hypothetical protein 1920873 6065297 EcolC_1724 Escherichia coli ATCC 8739 hypothetical protein YP_001724701.1 1920649 R 481805 CDS YP_001724702.1 170019748 6067209 1921332..1921988 1 NC_010468.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1921988 6067209 EcolC_1725 Escherichia coli ATCC 8739 response regulator YP_001724702.1 1921332 D 481805 CDS YP_001724703.1 170019749 6067201 1921985..1923817 1 NC_010468.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1923817 uvrC 6067201 uvrC Escherichia coli ATCC 8739 excinuclease ABC subunit C YP_001724703.1 1921985 D 481805 CDS YP_001724704.1 170019750 6067189 1923874..1924422 1 NC_010468.1 KEGG: sdy:SDY_1106 phosphatidylglycerophosphate synthetase CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyl transferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; phosphatidylglycerophosphate synthetase 1924422 6067189 EcolC_1727 Escherichia coli ATCC 8739 phosphatidylglycerophosphate synthetase YP_001724704.1 1923874 D 481805 CDS YP_001724705.1 170019751 6067082 1925071..1925736 1 NC_010468.1 TIGRFAM: yecA family protein; PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1098 hypothetical protein; hypothetical protein 1925736 6067082 EcolC_1728 Escherichia coli ATCC 8739 hypothetical protein YP_001724705.1 1925071 D 481805 CDS YP_001724706.1 170019752 6067012 complement(1925798..1927009) 1 NC_010468.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ssn:SSON_1211 tyrosine-specific transport system; aromatic amino acid transporter 1927009 6067012 EcolC_1729 Escherichia coli ATCC 8739 aromatic amino acid transporter YP_001724706.1 1925798 R 481805 CDS YP_001724707.1 170019753 6066925 1927199..1927438 1 NC_010468.1 KEGG: sfv:SFV_1950 hypothetical protein; hypothetical protein 1927438 6066925 EcolC_1730 Escherichia coli ATCC 8739 hypothetical protein YP_001724707.1 1927199 D 481805 CDS YP_001724708.1 170019754 6066920 complement(1927476..1927973) 1 NC_010468.1 cytoplasmic iron storage protein; ferritin 1927973 6066920 EcolC_1731 Escherichia coli ATCC 8739 ferritin YP_001724708.1 1927476 R 481805 CDS YP_001724709.1 170019755 6066634 complement(1928145..1928468) 1 NC_010468.1 KEGG: sdy:SDY_1114 hypothetical protein; hypothetical protein 1928468 6066634 EcolC_1732 Escherichia coli ATCC 8739 hypothetical protein YP_001724709.1 1928145 R 481805 CDS YP_001724710.1 170019756 6066192 complement(1929262..1929765) 1 NC_010468.1 PFAM: Ferritin Dps family protein; KEGG: sdy:SDY_1116 ferritin-like protein; ferritin Dps family protein 1929765 6066192 EcolC_1733 Escherichia coli ATCC 8739 ferritin Dps family protein YP_001724710.1 1929262 R 481805 CDS YP_001724711.1 170019757 6065782 1930562..1931551 1 NC_010468.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ssn:SSON_1217 L-arabinose-binding periplasmic protein; monosaccharide-transporting ATPase 1931551 6065782 EcolC_1734 Escherichia coli ATCC 8739 monosaccharide-transporting ATPase YP_001724711.1 1930562 D 481805 CDS YP_001724712.1 170019758 6065634 1931621..1933135 1 NC_010468.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1933135 araG 6065634 araG Escherichia coli ATCC 8739 L-arabinose transporter ATP-binding protein YP_001724712.1 1931621 D 481805 CDS YP_001724713.1 170019759 6065478 1933150..1934136 1 NC_010468.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1934136 araH 6065478 araH Escherichia coli ATCC 8739 L-arabinose transporter permease YP_001724713.1 1933150 D 481805 CDS YP_001724714.1 170019760 6065382 1934303..1935103 1 NC_010468.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1935103 6065382 EcolC_1737 Escherichia coli ATCC 8739 trehalose-6-phosphate phosphatase YP_001724714.1 1934303 D 481805 CDS YP_001724715.1 170019761 6065352 1935078..1936502 1 NC_010468.1 KEGG: sdy:SDY_1193 trehalose-6-phosphate synthase; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; PFAM: glycosyl transferase family 20; trehalose-6-phosphate synthase 1936502 6065352 EcolC_1738 Escherichia coli ATCC 8739 trehalose-6-phosphate synthase YP_001724715.1 1935078 D 481805 CDS YP_001724716.1 170019762 6068740 complement(1936509..1936937) 1 NC_010468.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1936937 6068740 EcolC_1739 Escherichia coli ATCC 8739 universal stress protein UspC YP_001724716.1 1936509 R 481805 CDS YP_001724717.1 170019763 6064752 1937716..1938066 1 NC_010468.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1938066 6064752 EcolC_1740 Escherichia coli ATCC 8739 transcriptional activator FlhD YP_001724717.1 1937716 D 481805 CDS YP_001724718.1 170019764 6067663 1938069..1938647 1 NC_010468.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1938647 6067663 EcolC_1741 Escherichia coli ATCC 8739 transcriptional activator FlhC YP_001724718.1 1938069 D 481805 CDS YP_001724719.1 170019765 6065298 1938774..1939661 1 NC_010468.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1939661 6065298 EcolC_1742 Escherichia coli ATCC 8739 flagellar motor protein MotA YP_001724719.1 1938774 D 481805 CDS YP_001724720.1 170019766 6064766 1939658..1940584 1 NC_010468.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1940584 motB 6064766 motB Escherichia coli ATCC 8739 flagellar motor protein MotB YP_001724720.1 1939658 D 481805 CDS YP_001724721.1 170019767 6066410 1940589..1942553 1 NC_010468.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1942553 6066410 EcolC_1744 Escherichia coli ATCC 8739 chemotaxis protein CheA YP_001724721.1 1940589 D 481805 CDS YP_001724722.1 170019768 6066862 1942574..1943077 1 NC_010468.1 PFAM: CheW domain protein; KEGG: ssn:SSON_1230 positive regulator of CheA protein activity; purine-binding chemotaxis protein 1943077 6066862 EcolC_1745 Escherichia coli ATCC 8739 purine-binding chemotaxis protein YP_001724722.1 1942574 D 481805 CDS YP_001724723.1 170019769 6065930 1943222..1944883 1 NC_010468.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ssn:SSON_1231 methyl-accepting chemotaxis protein II; methyl-accepting chemotaxis sensory transducer 1944883 6065930 EcolC_1746 Escherichia coli ATCC 8739 methyl-accepting chemotaxis sensory transducer YP_001724723.1 1943222 D 481805 CDS YP_001724724.1 170019770 6065952 1944929..1946530 1 NC_010468.1 mediates taxis toward dipeptides; methyl-accepting protein IV 1946530 6065952 EcolC_1747 Escherichia coli ATCC 8739 methyl-accepting protein IV YP_001724724.1 1944929 D 481805 CDS YP_001724725.1 170019771 6066325 1946549..1947409 1 NC_010468.1 methylates the MCP; chemotaxis methyltransferase CheR 1947409 6066325 EcolC_1748 Escherichia coli ATCC 8739 chemotaxis methyltransferase CheR YP_001724725.1 1946549 D 481805 CDS YP_001724726.1 170019772 6066189 1947412..1948461 1 NC_010468.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1948461 6066189 EcolC_1749 Escherichia coli ATCC 8739 chemotaxis-specific methylesterase YP_001724726.1 1947412 D 481805 CDS YP_001724727.1 170019773 6067360 1948476..1948865 1 NC_010468.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1948865 6067360 EcolC_1750 Escherichia coli ATCC 8739 chemotaxis regulatory protein CheY YP_001724727.1 1948476 D 481805 CDS YP_001724728.1 170019774 6066182 1948876..1949520 1 NC_010468.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1949520 6066182 EcolC_1751 Escherichia coli ATCC 8739 chemotaxis regulator CheZ YP_001724728.1 1948876 D 481805 CDS YP_001724729.1 170019775 6065327 1949722..1950870 1 NC_010468.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1950870 flhB 6065327 flhB Escherichia coli ATCC 8739 flagellar biosynthesis protein FlhB YP_001724729.1 1949722 D 481805 CDS YP_001724730.1 170019776 6065810 1950863..1952941 1 NC_010468.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1952941 flhA 6065810 flhA Escherichia coli ATCC 8739 flagellar biosynthesis protein FlhA YP_001724730.1 1950863 D 481805 CDS YP_001724731.1 170019777 6066161 1952941..1953333 1 NC_010468.1 PFAM: flagellar FlhE family protein; KEGG: sbo:SBO_1122 flagellar protein; flagellar FlhE family protein 1953333 6066161 EcolC_1754 Escherichia coli ATCC 8739 flagellar FlhE family protein YP_001724731.1 1952941 D 481805 CDS YP_001724732.1 170019778 6065258 complement(1953454..1953942) 1 NC_010468.1 PFAM: protein of unknown function DUF1311; KEGG: sbo:SBO_1123 hypothetical protein; hypothetical protein 1953942 6065258 EcolC_1755 Escherichia coli ATCC 8739 hypothetical protein YP_001724732.1 1953454 R 481805 CDS YP_001724733.1 170019779 6066595 complement(1954119..1955852) 1 NC_010468.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1955852 argS 6066595 argS Escherichia coli ATCC 8739 arginyl-tRNA synthetase YP_001724733.1 1954119 R 481805 CDS YP_001724734.1 170019780 6066474 1956068..1956634 1 NC_010468.1 PFAM: protein of unknown function DUF991; KEGG: sdy:SDY_1179 hypothetical protein; hypothetical protein 1956634 6066474 EcolC_1757 Escherichia coli ATCC 8739 hypothetical protein YP_001724734.1 1956068 D 481805 CDS YP_001724735.1 170019781 6065670 1956648..1957394 1 NC_010468.1 PFAM: CutC family protein; KEGG: sbo:SBO_1126 copper homeostasis protein; copper homeostasis protein CutC 1957394 6065670 EcolC_1758 Escherichia coli ATCC 8739 copper homeostasis protein CutC YP_001724735.1 1956648 D 481805 CDS YP_001724736.1 170019782 6066598 1957782..1958882 1 NC_010468.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: sfv:SFV_1911 putative cytochrome c-type protein; NapC/NirT cytochrome c domain-containing protein 1958882 6066598 EcolC_1759 Escherichia coli ATCC 8739 NapC/NirT cytochrome c domain-containing protein YP_001724736.1 1957782 D 481805 CDS YP_001724737.1 170019783 6065343 1958907..1961336 1 NC_010468.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfx:S2003 biotin sulfoxide reductase 2; molybdopterin guanine dinucleotide-containing S/N-oxide reductase 1961336 6065343 EcolC_1760 Escherichia coli ATCC 8739 molybdopterin guanine dinucleotide-containing S/N-oxide reductase YP_001724737.1 1958907 D 481805 CDS YP_001724738.1 170019784 6064523 complement(1961501..1962472) 1 NC_010468.1 TIGRFAM: methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; KEGG: sdy:SDY_1170 putative enzyme; methyltransferase 1962472 6064523 EcolC_1761 Escherichia coli ATCC 8739 methyltransferase YP_001724738.1 1961501 R 481805 CDS YP_001724739.1 170019785 6065581 complement(1962469..1963212) 1 NC_010468.1 TIGRFAM: methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdy:SDY_1169 hypothetical protein; methyltransferase 1963212 6065581 EcolC_1762 Escherichia coli ATCC 8739 methyltransferase YP_001724739.1 1962469 R 481805 CDS YP_001724740.1 170019786 6066768 complement(1963253..1963648) 1 NC_010468.1 KEGG: sdy:SDY_1168 hypothetical protein; hypothetical protein 1963648 6066768 EcolC_1763 Escherichia coli ATCC 8739 hypothetical protein YP_001724740.1 1963253 R 481805 CDS YP_001724741.1 170019787 6067390 complement(1963701..1964519) 1 NC_010468.1 PFAM: protein of unknown function DUF72; KEGG: stm:STM1903 putative cytoplasmic protein; hypothetical protein 1964519 6067390 EcolC_1764 Escherichia coli ATCC 8739 hypothetical protein YP_001724741.1 1963701 R 481805 CDS YP_001724742.1 170019788 6065663 complement(1964516..1965082) 1 NC_010468.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1274 hypothetical protein; hypothetical protein 1965082 6065663 EcolC_1765 Escherichia coli ATCC 8739 hypothetical protein YP_001724742.1 1964516 R 481805 CDS YP_001724743.1 170019789 6067667 1965392..1967164 1 NC_010468.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1967164 aspS 6067667 aspS Escherichia coli ATCC 8739 aspartyl-tRNA synthetase YP_001724743.1 1965392 D 481805 CDS YP_001724744.1 170019790 6066335 1967225..1967734 1 NC_010468.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1967734 ntpA 6066335 ntpA Escherichia coli ATCC 8739 dATP pyrophosphohydrolase YP_001724744.1 1967225 D 481805 CDS YP_001724745.1 170019791 6066988 1967763..1968503 1 NC_010468.1 PFAM: protein of unknown function DUF28; KEGG: ssn:SSON_1277 hypothetical protein; hypothetical protein 1968503 6066988 EcolC_1768 Escherichia coli ATCC 8739 hypothetical protein YP_001724745.1 1967763 D 481805 CDS YP_001724746.1 170019792 6065418 1968538..1969059 1 NC_010468.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1969059 ruvC 6065418 ruvC Escherichia coli ATCC 8739 Holliday junction resolvase YP_001724746.1 1968538 D 481805 CDS YP_001724747.1 170019793 6067561 complement(1969061..1969663) 1 NC_010468.1 PFAM: protein of unknown function DUF1105; KEGG: ssn:SSON_1279 hypothetical protein; hypothetical protein 1969663 6067561 EcolC_1770 Escherichia coli ATCC 8739 hypothetical protein YP_001724747.1 1969061 R 481805 CDS YP_001724748.1 170019794 6066611 1969938..1970549 1 NC_010468.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1970549 ruvA 6066611 ruvA Escherichia coli ATCC 8739 Holliday junction DNA helicase RuvA YP_001724748.1 1969938 D 481805 CDS YP_001724749.1 170019795 6065764 1970558..1971568 1 NC_010468.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1971568 ruvB 6065764 ruvB Escherichia coli ATCC 8739 Holliday junction DNA helicase RuvB YP_001724749.1 1970558 D 481805 CDS YP_001724750.1 170019796 6065117 complement(1971715..1972500) 1 NC_010468.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1972500 znuB 6065117 znuB Escherichia coli ATCC 8739 high-affinity zinc transporter membrane protein YP_001724750.1 1971715 R 481805 CDS YP_001724751.1 170019797 6067077 complement(1972497..1973252) 1 NC_010468.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1973252 znuC 6067077 znuC Escherichia coli ATCC 8739 high-affinity zinc transporter ATPase YP_001724751.1 1972497 R 481805 CDS YP_001724752.1 170019798 6067074 1973331..1974263 1 NC_010468.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1974263 znuA 6067074 znuA Escherichia coli ATCC 8739 high-affinity zinc transporter periplasmic protein YP_001724752.1 1973331 D 481805 CDS YP_001724753.1 170019799 6065745 1974279..1975601 1 NC_010468.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sbo:SBO_1173 hypothetical protein; hypothetical protein 1975601 6065745 EcolC_1776 Escherichia coli ATCC 8739 hypothetical protein YP_001724753.1 1974279 D 481805 CDS YP_001724754.1 170019800 6067163 1975721..1976692 1 NC_010468.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1976692 6067163 EcolC_1777 Escherichia coli ATCC 8739 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_001724754.1 1975721 D 481805 CDS YP_001724755.1 170019801 6066850 complement(1976823..1978265) 1 NC_010468.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1978265 6066850 EcolC_1778 Escherichia coli ATCC 8739 pyruvate kinase YP_001724755.1 1976823 R 481805 CDS YP_001724756.1 170019802 6064936 complement(1978393..1979262) 1 NC_010468.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1979262 6064936 EcolC_1779 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator HexR YP_001724756.1 1978393 R 481805 CDS YP_001724757.1 170019803 6067322 1979600..1981075 1 NC_010468.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1981075 6067322 EcolC_1780 Escherichia coli ATCC 8739 glucose-6-phosphate 1-dehydrogenase YP_001724757.1 1979600 D 481805 CDS YP_001724758.1 170019804 6066403 1981310..1983121 1 NC_010468.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1983121 6066403 EcolC_1781 Escherichia coli ATCC 8739 phosphogluconate dehydratase YP_001724758.1 1981310 D 481805 CDS YP_001724759.1 170019805 6065731 1983158..1983799 1 NC_010468.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1983799 6065731 EcolC_1782 Escherichia coli ATCC 8739 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001724759.1 1983158 D 481805 CDS YP_001724760.1 170019806 6064921 complement(1983855..1985033) 1 NC_010468.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1985033 purT 6064921 purT Escherichia coli ATCC 8739 phosphoribosylglycinamide formyltransferase 2 YP_001724760.1 1983855 R 481805 CDS YP_001724761.1 170019807 6065548 1985167..1985457 1 NC_010468.1 PFAM: YebG family protein; KEGG: sdy:SDY_1134 hypothetical protein; DNA damage-inducible protein YebG 1985457 6065548 EcolC_1784 Escherichia coli ATCC 8739 DNA damage-inducible protein YebG YP_001724761.1 1985167 D 481805 CDS YP_001724762.1 170019808 6066917 1985524..1985880 1 NC_010468.1 secreted protein; unknown function; hypothetical protein 1985880 6066917 EcolC_1785 Escherichia coli ATCC 8739 hypothetical protein YP_001724762.1 1985524 D 481805 CDS YP_001724763.1 170019809 6066716 1986207..1986866 1 NC_010468.1 PFAM: protein of unknown function DUF533; KEGG: sdy:SDY_1132 hypothetical protein; hypothetical protein 1986866 6066716 EcolC_1786 Escherichia coli ATCC 8739 hypothetical protein YP_001724763.1 1986207 D 481805 CDS YP_001724764.1 170019810 6066560 1987075..1989135 1 NC_010468.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1989135 6066560 EcolC_1787 Escherichia coli ATCC 8739 protease 2 YP_001724764.1 1987075 D 481805 CDS YP_001724765.1 170019811 6065309 complement(1989132..1989794) 1 NC_010468.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1989794 6065309 EcolC_1788 Escherichia coli ATCC 8739 exodeoxyribonuclease X YP_001724765.1 1989132 R 481805 CDS YP_001724766.1 170019812 6065759 complement(1989818..1990474) 1 NC_010468.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ssn:SSON_1305 hypothetical protein; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 1990474 6065759 EcolC_1789 Escherichia coli ATCC 8739 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001724766.1 1989818 R 481805 CDS YP_001724767.1 170019813 6064675 complement(1990576..1990806) 1 NC_010468.1 PFAM: DNA polymerase II beta subunit; KEGG: sdy:SDY_1128 DNA polymerase III, theta subunit; DNA polymerase III subunit theta 1990806 6064675 EcolC_1790 Escherichia coli ATCC 8739 DNA polymerase III subunit theta YP_001724767.1 1990576 R 481805 CDS YP_001724768.1 170019814 6066141 1990945..1991319 1 NC_010468.1 PFAM: copper resistance protein CopC; KEGG: sbo:SBO_1145 hypothetical protein; hypothetical protein 1991319 6066141 EcolC_1791 Escherichia coli ATCC 8739 hypothetical protein YP_001724768.1 1990945 D 481805 CDS YP_001724769.1 170019815 6066319 1991323..1992195 1 NC_010468.1 PFAM: copper resistance D domain protein; KEGG: ssn:SSON_1308 putative resistance protein; copper resistance D domain-containing protein 1992195 6066319 EcolC_1792 Escherichia coli ATCC 8739 copper resistance D domain-containing protein YP_001724769.1 1991323 D 481805 CDS YP_001724770.1 170019816 6068745 1992211..1992549 1 NC_010468.1 KEGG: sdy:SDY_1125 hypothetical protein; hypothetical protein 1992549 6068745 EcolC_1793 Escherichia coli ATCC 8739 hypothetical protein YP_001724770.1 1992211 D 481805 CDS YP_001724771.1 170019817 6064762 1992945..1993601 1 NC_010468.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1993601 pphA 6064762 pphA Escherichia coli ATCC 8739 serine/threonine protein phosphatase 1 YP_001724771.1 1992945 D 481805 CDS YP_001724772.1 170019818 6065210 complement(1993602..1993877) 1 NC_010468.1 PFAM: protein of unknown function DUF1482; KEGG: sdy:SDY_1988 hypothetical protein; hypothetical protein 1993877 6065210 EcolC_1795 Escherichia coli ATCC 8739 hypothetical protein YP_001724772.1 1993602 R 481805 CDS YP_001724773.1 170019819 6065925 complement(1993898..1994134) 1 NC_010468.1 PFAM: protein of unknown function DUF1480; KEGG: sdy:SDY_1987 hypothetical protein; hypothetical protein 1994134 6065925 EcolC_1796 Escherichia coli ATCC 8739 hypothetical protein YP_001724773.1 1993898 R 481805 CDS YP_001724774.1 170019820 6066012 complement(1994252..1995697) 1 NC_010468.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1995697 yebU 6066012 yebU Escherichia coli ATCC 8739 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_001724774.1 1994252 R 481805 CDS YP_001724775.1 170019821 6065174 complement(1995771..1998404) 1 NC_010468.1 PFAM: Mammalian cell entry related domain protein; KEGG: ssn:SSON_1327 hypothetical protein; hypothetical protein 1998404 6065174 EcolC_1798 Escherichia coli ATCC 8739 hypothetical protein YP_001724775.1 1995771 R 481805 CDS YP_001724776.1 170019822 6065646 complement(1998373..1999656) 1 NC_010468.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: ssn:SSON_1328 hypothetical protein; PqiA family integral membrane protein 1999656 6065646 EcolC_1799 Escherichia coli ATCC 8739 PqiA family integral membrane protein YP_001724776.1 1998373 R 481805 CDS YP_001724777.1 170019823 6066671 1999786..2000283 1 NC_010468.1 PFAM: GAF domain protein; KEGG: sdy:SDY_1980 hypothetical protein; putative GAF sensor protein 2000283 6066671 EcolC_1800 Escherichia coli ATCC 8739 putative GAF sensor protein YP_001724777.1 1999786 D 481805 CDS YP_001724778.1 170019824 6064725 2000380..2001078 1 NC_010468.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 2001078 6064725 EcolC_1801 Escherichia coli ATCC 8739 putative solute/DNA competence effector YP_001724778.1 2000380 D 481805 CDS YP_001724779.1 170019825 6064474 2001098..2003146 1 NC_010468.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2003146 6064474 EcolC_1802 Escherichia coli ATCC 8739 carboxy-terminal protease YP_001724779.1 2001098 D 481805 CDS YP_001724780.1 170019826 6065721 2003338..2004219 1 NC_010468.1 putative metalloprotease; heat shock protein HtpX 2004219 6065721 EcolC_1803 Escherichia coli ATCC 8739 heat shock protein HtpX YP_001724780.1 2003338 D 481805 CDS YP_001724781.1 170019827 6065836 complement(2004265..2005638) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1241 putative transport protein; major facilitator transporter 2005638 6065836 EcolC_1804 Escherichia coli ATCC 8739 major facilitator transporter YP_001724781.1 2004265 R 481805 CDS YP_001724782.1 170019828 6065812 2005815..2006606 1 NC_010468.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sbo:SBO_1240 putative regulator; IclR family transcriptional regulator 2006606 6065812 EcolC_1805 Escherichia coli ATCC 8739 IclR family transcriptional regulator YP_001724782.1 2005815 D 481805 CDS YP_001724783.1 170019829 6067213 complement(2006749..2006988) 1 NC_010468.1 KEGG: sdy:SDY_1974 hypothetical protein; hypothetical protein 2006988 6067213 EcolC_1806 Escherichia coli ATCC 8739 hypothetical protein YP_001724783.1 2006749 R 481805 CDS YP_001724784.1 170019830 6066551 2007147..2007290 1 NC_010468.1 KEGG: sdy:SDY_1973 hypothetical protein; hypothetical protein 2007290 6066551 EcolC_1807 Escherichia coli ATCC 8739 hypothetical protein YP_001724784.1 2007147 D 481805 CDS YP_001724785.1 170019831 6067493 2007365..2007652 1 NC_010468.1 KEGG: sbo:SBO_1238 hypothetical protein; hypothetical protein 2007652 6067493 EcolC_1808 Escherichia coli ATCC 8739 hypothetical protein YP_001724785.1 2007365 D 481805 CDS YP_001724786.1 170019832 6066552 complement(2008435..2008722) 1 NC_010468.1 KEGG: cko:CKO_01153 hypothetical protein; hypothetical protein 2008722 6066552 EcolC_1809 Escherichia coli ATCC 8739 hypothetical protein YP_001724786.1 2008435 R 481805 CDS YP_001724787.1 170019833 6066454 2008852..2009661 1 NC_010468.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 2009661 rrmA 6066454 rrmA Escherichia coli ATCC 8739 23S rRNA methyltransferase A YP_001724787.1 2008852 D 481805 CDS YP_001724788.1 170019834 6066414 complement(2009658..2010224) 1 NC_010468.1 membrane protein YebN; hypothetical protein 2010224 6066414 EcolC_1811 Escherichia coli ATCC 8739 hypothetical protein YP_001724788.1 2009658 R 481805 CDS YP_001724789.1 170019835 6066288 complement(2010653..2011111) 1 NC_010468.1 PFAM: protein of unknown function DUF986; KEGG: sdy:SDY_1966 hypothetical protein; hypothetical protein 2011111 6066288 EcolC_1812 Escherichia coli ATCC 8739 hypothetical protein YP_001724789.1 2010653 R 481805 CDS YP_001724790.1 170019836 6066112 complement(2011166..2012017) 1 NC_010468.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2012017 6066112 EcolC_1813 Escherichia coli ATCC 8739 PTS system mannose-specific transporter subunit IID YP_001724790.1 2011166 R 481805 CDS YP_001724791.1 170019837 6066144 complement(2012030..2012830) 1 NC_010468.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sbo:SBO_1230 PTS enzyme IIC, mannose-specific; PTS system mannose/fructose/sorbose family transporter subunit IIC subunit 2012830 6066144 EcolC_1814 Escherichia coli ATCC 8739 PTS system mannose/fructose/sorbose family transporter subunit IIC subunit YP_001724791.1 2012030 R 481805 CDS YP_001724792.1 170019838 6066566 complement(join(2013171..2013614,2013614..2013868)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 2013868 6066566 EcolC_1816 Escherichia coli ATCC 8739 insertion element protein YP_001724792.1 2013171 R 481805 CDS YP_001724793.1 170019839 6064727 2015104..2016660 1 NC_010468.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: sbo:SBO_1228 putative transport protein; integral membrane protein TerC 2016660 6064727 EcolC_1817 Escherichia coli ATCC 8739 integral membrane protein TerC YP_001724793.1 2015104 D 481805 CDS YP_001724794.1 170019840 6065043 complement(2016664..2018262) 1 NC_010468.1 PFAM: EAL domain protein; KEGG: ssn:SSON_1345 hypothetical protein; diguanylate phosphodiesterase 2018262 6065043 EcolC_1818 Escherichia coli ATCC 8739 diguanylate phosphodiesterase YP_001724794.1 2016664 R 481805 CDS YP_001724795.1 170019841 6064759 complement(2018393..2019757) 1 NC_010468.1 KEGG: sbo:SBO_1270 L-serine deaminase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 2019757 6064759 EcolC_1819 Escherichia coli ATCC 8739 L-serine dehydratase 1 YP_001724795.1 2018393 R 481805 CDS YP_001724796.1 170019842 6065776 complement(2019941..2020519) 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1719 hypothetical protein; hypothetical protein 2020519 6065776 EcolC_1820 Escherichia coli ATCC 8739 hypothetical protein YP_001724796.1 2019941 R 481805 CDS YP_001724797.1 170019843 6065498 complement(2020523..2021884) 1 NC_010468.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: ssn:SSON_1348 p-aminobenzoate synthetase, component I; para-aminobenzoate synthase subunit I 2021884 6065498 EcolC_1821 Escherichia coli ATCC 8739 para-aminobenzoate synthase subunit I YP_001724797.1 2020523 R 481805 CDS YP_001724798.1 170019844 6066888 2021958..2022137 1 NC_010468.1 PFAM: protein of unknown function UPF0181; KEGG: sdy:SDY_1717 hypothetical protein; hypothetical protein 2022137 6066888 EcolC_1822 Escherichia coli ATCC 8739 hypothetical protein YP_001724798.1 2021958 D 481805 CDS YP_001724799.1 170019845 6066570 complement(2022257..2022556) 1 NC_010468.1 PFAM: Domain of unknown function DUF1889; KEGG: sbo:SBO_1276 hypothetical protein; hypothetical protein 2022556 6066570 EcolC_1823 Escherichia coli ATCC 8739 hypothetical protein YP_001724799.1 2022257 R 481805 CDS YP_001724800.1 170019846 6066131 complement(2022978..2023325) 1 NC_010468.1 PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_1713 hypothetical protein; endoribonuclease L-PSP 2023325 6066131 EcolC_1824 Escherichia coli ATCC 8739 endoribonuclease L-PSP YP_001724800.1 2022978 R 481805 CDS YP_001724801.1 170019847 6065726 2023454..2025364 1 NC_010468.1 SMART: helicase c2; DEAD-like helicases; KEGG: sbo:SBO_1280 putative enzyme; helicase c2 2025364 6065726 EcolC_1825 Escherichia coli ATCC 8739 helicase c2 YP_001724801.1 2023454 D 481805 CDS YP_001724802.1 170019848 6065299 2025422..2026117 1 NC_010468.1 PFAM: peptidase M22 glycoprotease; KEGG: sfv:SFV_1422 hypothetical protein; peptidase M22 glycoprotease 2026117 6065299 EcolC_1826 Escherichia coli ATCC 8739 peptidase M22 glycoprotease YP_001724802.1 2025422 D 481805 CDS YP_001724803.1 170019849 6066770 2026157..2026738 1 NC_010468.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sfv:SFV_1423 putative outer membrane protein; Slp family outer membrane lipoprotein 2026738 6066770 EcolC_1827 Escherichia coli ATCC 8739 Slp family outer membrane lipoprotein YP_001724803.1 2026157 D 481805 CDS YP_001724804.1 170019850 6065267 2026877..2028628 1 NC_010468.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2028628 6065267 EcolC_1828 Escherichia coli ATCC 8739 long-chain-fatty-acid--CoA ligase YP_001724804.1 2026877 D 481805 CDS YP_001724805.1 170019851 6064477 2028710..2029825 1 NC_010468.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: sfv:SFV_1425 RNase D, processes tRNA precursor; ribonuclease D 2029825 6064477 EcolC_1829 Escherichia coli ATCC 8739 ribonuclease D YP_001724805.1 2028710 D 481805 CDS YP_001724806.1 170019852 6065712 complement(2029878..2030843) 1 NC_010468.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ssn:SSON_1358 putative diogenase beta subunit; ferredoxin 2030843 6065712 EcolC_1830 Escherichia coli ATCC 8739 ferredoxin YP_001724806.1 2029878 R 481805 CDS YP_001724807.1 170019853 6067413 complement(2030899..2032023) 1 NC_010468.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_1359 hypothetical protein; Rieske (2Fe-2S) domain-containing protein 2032023 6067413 EcolC_1831 Escherichia coli ATCC 8739 Rieske (2Fe-2S) domain-containing protein YP_001724807.1 2030899 R 481805 CDS YP_001724808.1 170019854 6065852 complement(2032055..2033500) 1 NC_010468.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; putative transporter 2033500 6065852 EcolC_1832 Escherichia coli ATCC 8739 putative transporter YP_001724808.1 2032055 R 481805 CDS YP_001724809.1 170019855 6064885 complement(2033691..2034776) 1 NC_010468.1 KEGG: ssn:SSON_1361 putative tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase 2034776 6064885 EcolC_1833 Escherichia coli ATCC 8739 tartrate dehydrogenase YP_001724809.1 2033691 R 481805 CDS YP_001724810.1 170019856 6065576 2034879..2035802 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1289 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2035802 6065576 EcolC_1834 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001724810.1 2034879 D 481805 CDS YP_001724811.1 170019857 6064927 2035929..2036567 1 NC_010468.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sdy:SDY_1698 hypothetical protein; leucine export protein LeuE 2036567 6064927 EcolC_1835 Escherichia coli ATCC 8739 leucine export protein LeuE YP_001724811.1 2035929 D 481805 CDS YP_001724812.1 170019858 6064604 2036740..2037099 1 NC_010468.1 PFAM: Protein of unknown function DUF1971; KEGG: sdy:SDY_1697 hypothetical protein; hypothetical protein 2037099 6064604 EcolC_1836 Escherichia coli ATCC 8739 hypothetical protein YP_001724812.1 2036740 D 481805 CDS YP_001724813.1 170019859 6065786 2037103..2037285 1 NC_010468.1 PFAM: Domain of unknown function DUF1869; KEGG: sdy:SDY_1696 hypothetical protein; hypothetical protein 2037285 6065786 EcolC_1837 Escherichia coli ATCC 8739 hypothetical protein YP_001724813.1 2037103 D 481805 CDS YP_001724814.1 170019860 6066211 2037433..2037681 1 NC_010468.1 PFAM: Transglycosylase-associated protein; KEGG: sdy:SDY_1695 hypothetical protein; hypothetical protein 2037681 6066211 EcolC_1838 Escherichia coli ATCC 8739 hypothetical protein YP_001724814.1 2037433 D 481805 CDS YP_001724815.1 170019861 6066355 complement(2037948..2038973) 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: sdy:SDY_1692 hypothetical protein; GAF sensor-containing diguanylate cyclase 2038973 6066355 EcolC_1839 Escherichia coli ATCC 8739 GAF sensor-containing diguanylate cyclase YP_001724815.1 2037948 R 481805 CDS YP_001724816.1 170019862 6067117 2039156..2039410 1 NC_010468.1 PFAM: protein of unknown function DUF333; KEGG: sfx:S1546 hypothetical protein; hypothetical protein 2039410 6067117 EcolC_1840 Escherichia coli ATCC 8739 hypothetical protein YP_001724816.1 2039156 D 481805 CDS YP_001724817.1 170019863 6065441 complement(2039432..2039779) 1 NC_010468.1 PFAM: protein of unknown function DUF488; KEGG: ssn:SSON_1369 hypothetical protein; hypothetical protein 2039779 6065441 EcolC_1841 Escherichia coli ATCC 8739 hypothetical protein YP_001724817.1 2039432 R 481805 CDS YP_001724818.1 170019864 6066494 complement(2039834..2041015) 1 NC_010468.1 TIGRFAM: cyanate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1302 putative amino acid/amine transport protein; cyanate transporter 2041015 6066494 EcolC_1842 Escherichia coli ATCC 8739 cyanate transporter YP_001724818.1 2039834 R 481805 CDS YP_001724819.1 170019865 6064711 2041112..2041933 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_1688 putative AraC-type regulatory protein; AraC family transcriptional regulator 2041933 6064711 EcolC_1843 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001724819.1 2041112 D 481805 CDS YP_001724820.1 170019866 6066503 complement(2041890..2042336) 1 NC_010468.1 PFAM: protein of unknown function DUF441; KEGG: sbo:SBO_1304 hypothetical protein; hypothetical protein 2042336 6066503 EcolC_1844 Escherichia coli ATCC 8739 hypothetical protein YP_001724820.1 2041890 R 481805 CDS YP_001724821.1 170019867 6064658 complement(2042611..2043114) 1 NC_010468.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sbo:SBO_1306 hypothetical protein; YbaK/prolyl-tRNA synthetase associated domain-containing protein 2043114 6064658 EcolC_1845 Escherichia coli ATCC 8739 YbaK/prolyl-tRNA synthetase associated domain-containing protein YP_001724821.1 2042611 R 481805 CDS YP_001724822.1 170019868 6065158 complement(2043157..2044647) 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1375 hypothetical protein; diguanylate cyclase 2044647 6065158 EcolC_1846 Escherichia coli ATCC 8739 diguanylate cyclase YP_001724822.1 2043157 R 481805 CDS YP_001724823.1 170019869 6067436 complement(2044828..2046303) 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1377 hypothetical protein; diguanylate cyclase 2046303 6067436 EcolC_1847 Escherichia coli ATCC 8739 diguanylate cyclase YP_001724823.1 2044828 R 481805 CDS YP_001724824.1 170019870 6065222 complement(2046450..2047733) 1 NC_010468.1 PFAM: protein of unknown function DUF444; KEGG: sbo:SBO_1309 hypothetical protein; hypothetical protein 2047733 6065222 EcolC_1848 Escherichia coli ATCC 8739 hypothetical protein YP_001724824.1 2046450 R 481805 CDS YP_001724825.1 170019871 6065589 complement(2047846..2049780) 1 NC_010468.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: sbo:SBO_1310 hypothetical protein; putative serine protein kinase PrkA 2049780 6065589 EcolC_1849 Escherichia coli ATCC 8739 putative serine protein kinase PrkA YP_001724825.1 2047846 R 481805 CDS YP_001724826.1 170019872 6067669 2050216..2050962 1 NC_010468.1 PFAM: MltA-interacting MipA family protein; KEGG: sdy:SDY_1485 hypothetical protein; MltA-interacting MipA family protein 2050962 6067669 EcolC_1850 Escherichia coli ATCC 8739 MltA-interacting MipA family protein YP_001724826.1 2050216 D 481805 CDS YP_001724827.1 170019873 6066300 2051052..2051906 1 NC_010468.1 PFAM: aldo/keto reductase; KEGG: ssn:SSON_1381 putative an aldehyde reductase; aldo/keto reductase 2051906 6066300 EcolC_1851 Escherichia coli ATCC 8739 aldo/keto reductase YP_001724827.1 2051052 D 481805 CDS YP_001724828.1 170019874 6065799 complement(2051954..2052838) 1 NC_010468.1 PFAM: Aldose 1-epimerase; KEGG: sfv:SFV_1435 hypothetical protein; aldose 1-epimerase 2052838 6065799 EcolC_1852 Escherichia coli ATCC 8739 aldose 1-epimerase YP_001724828.1 2051954 R 481805 CDS YP_001724829.1 170019875 6065095 complement(2052922..2053917) 1 NC_010468.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: sdy:SDY_1488 glyceraldehyde-3-phosphate dehydrogenase A; glyceraldehyde-3-phosphate dehydrogenase 2053917 6065095 EcolC_1853 Escherichia coli ATCC 8739 glyceraldehyde-3-phosphate dehydrogenase YP_001724829.1 2052922 R 481805 CDS YP_001724830.1 170019876 6065671 2054259..2054672 1 NC_010468.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2054672 6065671 EcolC_1854 Escherichia coli ATCC 8739 methionine sulfoxide reductase B YP_001724830.1 2054259 D 481805 CDS YP_001724831.1 170019877 6066362 2054714..2054986 1 NC_010468.1 PFAM: protein of unknown function DUF1315; KEGG: sbo:SBO_1318 hypothetical protein; hypothetical protein 2054986 6066362 EcolC_1855 Escherichia coli ATCC 8739 hypothetical protein YP_001724831.1 2054714 D 481805 CDS YP_001724832.1 170019878 6066490 2055356..2056432 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_1491 putative oxidoreductase; alcohol dehydrogenase 2056432 6066490 EcolC_1856 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001724832.1 2055356 D 481805 CDS YP_001724833.1 170019879 6065264 2056459..2057838 1 NC_010468.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_1492 putative transport protein; major facilitator transporter 2057838 6065264 EcolC_1857 Escherichia coli ATCC 8739 major facilitator transporter YP_001724833.1 2056459 D 481805 CDS YP_001724834.1 170019880 6065152 2057855..2058898 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sec:SC1309 hypothetical zinc-type alcohol dehydrogenase-like; alcohol dehydrogenase 2058898 6065152 EcolC_1858 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001724834.1 2057855 D 481805 CDS YP_001724835.1 170019881 6065905 2058919..2059755 1 NC_010468.1 KEGG: sfx:S1565 putative aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; ketose-bisphosphate aldolase 2059755 6065905 EcolC_1859 Escherichia coli ATCC 8739 ketose-bisphosphate aldolase YP_001724835.1 2058919 D 481805 CDS YP_001724836.1 170019882 6066926 2059760..2060707 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: sfx:S1566 putative kinase; ribokinase-like domain-containing protein 2060707 6066926 EcolC_1860 Escherichia coli ATCC 8739 ribokinase-like domain-containing protein YP_001724836.1 2059760 D 481805 CDS YP_001724837.1 170019883 6066746 2061835..2062593 1 NC_010468.1 PFAM: regulatory protein DeoR; KEGG: sdy:SDY_1498 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 2062593 6066746 EcolC_1862 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001724837.1 2061835 D 481805 CDS YP_001724838.1 170019884 6066677 2062711..2064069 1 NC_010468.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sfx:S1569 putative transport protein; major facilitator transporter 2064069 6066677 EcolC_1863 Escherichia coli ATCC 8739 major facilitator transporter YP_001724838.1 2062711 D 481805 CDS YP_001724839.1 170019885 6067501 complement(2064162..2064803) 1 NC_010468.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2064803 6067501 EcolC_1864 Escherichia coli ATCC 8739 nicotinamidase/pyrazinamidase YP_001724839.1 2064162 R 481805 CDS YP_001724840.1 170019886 6064843 complement(2064814..2065830) 1 NC_010468.1 converts asparagine to aspartate and ammonia; asparaginase 2065830 ansA 6064843 ansA Escherichia coli ATCC 8739 asparaginase YP_001724840.1 2064814 R 481805 CDS YP_001724841.1 170019887 6066463 complement(2065997..2067853) 1 NC_010468.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2067853 6066463 EcolC_1866 Escherichia coli ATCC 8739 protease 4 YP_001724841.1 2065997 R 481805 CDS YP_001724842.1 170019888 6065245 2068014..2068565 1 NC_010468.1 PFAM: nitroreductase; KEGG: sbo:SBO_1322 hypothetical protein; hypothetical protein 2068565 6065245 EcolC_1867 Escherichia coli ATCC 8739 hypothetical protein YP_001724842.1 2068014 D 481805 CDS YP_001724843.1 170019889 6064451 2068682..2069725 1 NC_010468.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2069725 6064451 EcolC_1868 Escherichia coli ATCC 8739 selenophosphate synthetase YP_001724843.1 2068682 D 481805 CDS YP_001724844.1 170019890 6064430 2069730..2071691 1 NC_010468.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2071691 6064430 EcolC_1869 Escherichia coli ATCC 8739 DNA topoisomerase III YP_001724844.1 2069730 D 481805 CDS YP_001724845.1 170019891 6064419 2071819..2072859 1 NC_010468.1 KEGG: sfl:SF1461 hypothetical protein; hypothetical protein 2072859 6064419 EcolC_1870 Escherichia coli ATCC 8739 hypothetical protein YP_001724845.1 2071819 D 481805 CDS YP_001724846.1 170019892 6064390 complement(2072976..2074319) 1 NC_010468.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2074319 6064390 EcolC_1871 Escherichia coli ATCC 8739 glutamate dehydrogenase YP_001724846.1 2072976 R 481805 CDS YP_001724847.1 170019893 6064379 2074555..2074827 1 NC_010468.1 PFAM: protein of unknown function DUF1496; KEGG: sbo:SBO_1329 hypothetical protein; hypothetical protein 2074827 6064379 EcolC_1872 Escherichia coli ATCC 8739 hypothetical protein YP_001724847.1 2074555 D 481805 CDS YP_001724848.1 170019894 6064370 complement(2074793..2075200) 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1516 hypothetical protein; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2075200 6064370 EcolC_1873 Escherichia coli ATCC 8739 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_001724848.1 2074793 R 481805 CDS YP_001724849.1 170019895 6064365 2075287..2075907 1 NC_010468.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfx:S1582 putative cytochrome oxidase; CDP-alcohol phosphatidyltransferase 2075907 6064365 EcolC_1874 Escherichia coli ATCC 8739 CDP-alcohol phosphatidyltransferase YP_001724849.1 2075287 D 481805 CDS YP_001724850.1 170019896 6064353 complement(2075916..2077223) 1 NC_010468.1 SMART: Rhodanese domain protein; KEGG: sbo:SBO_1332 putative thiosulfate sulfur transferase; rhodanese domain-containing protein 2077223 6064353 EcolC_1875 Escherichia coli ATCC 8739 rhodanese domain-containing protein YP_001724850.1 2075916 R 481805 CDS YP_001724851.1 170019897 6064347 complement(2077290..2077943) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_1462 putative ATP-binding component of a transport system; ABC transporter-like protein 2077943 6064347 EcolC_1876 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001724851.1 2077290 R 481805 CDS YP_001724852.1 170019898 6068094 complement(2077943..2079478) 1 NC_010468.1 KEGG: sdy:SDY_1520 putative transport system permease protein; putative transport system permease 2079478 6068094 EcolC_1877 Escherichia coli ATCC 8739 putative transport system permease YP_001724852.1 2077943 R 481805 CDS YP_001724853.1 170019899 6067632 complement(2079451..2080617) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1403 hypothetical protein; putative ABC transporter solute-binding protein 2080617 6067632 EcolC_1878 Escherichia coli ATCC 8739 putative ABC transporter solute-binding protein YP_001724853.1 2079451 R 481805 CDS YP_001724854.1 170019900 6067353 complement(2080627..2081175) 1 NC_010468.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: sbo:SBO_1336 hypothetical protein; carboxymuconolactone decarboxylase 2081175 6067353 EcolC_1879 Escherichia coli ATCC 8739 carboxymuconolactone decarboxylase YP_001724854.1 2080627 R 481805 CDS YP_001724855.1 170019901 6066927 complement(2081175..2081882) 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_1468 hypothetical protein; hypothetical protein 2081882 6066927 EcolC_1880 Escherichia coli ATCC 8739 hypothetical protein YP_001724855.1 2081175 R 481805 CDS YP_001724856.1 170019902 6068736 complement(2081897..2082574) 1 NC_010468.1 KEGG: ssn:SSON_1406 hypothetical protein; hypothetical protein 2082574 6068736 EcolC_1881 Escherichia coli ATCC 8739 hypothetical protein YP_001724856.1 2081897 R 481805 CDS YP_001724857.1 170019903 6065204 complement(2082579..2083289) 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_1407 hypothetical protein; hypothetical protein 2083289 6065204 EcolC_1882 Escherichia coli ATCC 8739 hypothetical protein YP_001724857.1 2082579 R 481805 CDS YP_001724858.1 170019904 6065201 complement(2083456..2084274) 1 NC_010468.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2084274 6065201 EcolC_1883 Escherichia coli ATCC 8739 exonuclease III YP_001724858.1 2083456 R 481805 CDS YP_001724859.1 170019905 6065166 2084708..2085928 1 NC_010468.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 2085928 6065166 EcolC_1884 Escherichia coli ATCC 8739 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_001724859.1 2084708 D 481805 CDS YP_001724860.1 170019906 6065150 2085925..2086959 1 NC_010468.1 KEGG: sdy:SDY_1530 hypothetical protein; TIGRFAM: arginine/ornithine succinyltransferase subunit; arginine N-succinyltransferase; PFAM: arginine N-succinyltransferase beta subunit; arginine succinyltransferase 2086959 6065150 EcolC_1885 Escherichia coli ATCC 8739 arginine succinyltransferase YP_001724860.1 2085925 D 481805 CDS YP_001724861.1 170019907 6065099 2086956..2088434 1 NC_010468.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2088434 astD 6065099 astD Escherichia coli ATCC 8739 succinylglutamic semialdehyde dehydrogenase YP_001724861.1 2086956 D 481805 CDS YP_001724862.1 170019908 6065089 2088431..2089774 1 NC_010468.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 2089774 6065089 EcolC_1887 Escherichia coli ATCC 8739 succinylarginine dihydrolase YP_001724862.1 2088431 D 481805 CDS YP_001724863.1 170019909 6065027 2089767..2090735 1 NC_010468.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 2090735 6065027 EcolC_1888 Escherichia coli ATCC 8739 succinylglutamate desuccinylase YP_001724863.1 2089767 D 481805 CDS YP_001724864.1 170019910 6065021 2091065..2091550 1 NC_010468.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 2091550 6065021 EcolC_1889 Escherichia coli ATCC 8739 hypothetical protein YP_001724864.1 2091065 D 481805 CDS YP_001724865.1 170019911 6065015 2091753..2092328 1 NC_010468.1 PFAM: protein of unknown function DUF886; KEGG: sbo:SBO_1348 hypothetical protein; hypothetical protein 2092328 6065015 EcolC_1890 Escherichia coli ATCC 8739 hypothetical protein YP_001724865.1 2091753 D 481805 CDS YP_001724866.1 170019912 6064956 complement(2092288..2093175) 1 NC_010468.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2093175 6064956 EcolC_1891 Escherichia coli ATCC 8739 nucleotide excision repair endonuclease YP_001724866.1 2092288 R 481805 CDS YP_001724867.1 170019913 6064933 complement(2093405..2094232) 1 NC_010468.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2094232 nadE 6064933 nadE Escherichia coli ATCC 8739 NAD synthetase YP_001724867.1 2093405 R 481805 CDS YP_001724868.1 170019914 6064834 2094434..2094772 1 NC_010468.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 2094772 6064834 EcolC_1893 Escherichia coli ATCC 8739 DNA-binding transcriptional activator OsmE YP_001724868.1 2094434 D 481805 CDS YP_001724869.1 170019915 6064778 2095071..2095391 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2095391 6064778 EcolC_1894 Escherichia coli ATCC 8739 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_001724869.1 2095071 D 481805 CDS YP_001724870.1 170019916 6064733 2095476..2096834 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2096834 6064733 EcolC_1895 Escherichia coli ATCC 8739 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_001724870.1 2095476 D 481805 CDS YP_001724871.1 170019917 6064713 2096885..2097235 1 NC_010468.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2097235 6064713 EcolC_1896 Escherichia coli ATCC 8739 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_001724871.1 2096885 D 481805 CDS YP_001724872.1 170019918 6064703 2097246..2098085 1 NC_010468.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 2098085 6064703 EcolC_1897 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator ChbR YP_001724872.1 2097246 D 481805 CDS YP_001724873.1 170019919 6064701 2098189..2099541 1 NC_010468.1 PFAM: glycoside hydrolase family 4; KEGG: sfx:S1611 cryptic phospho-beta-glucosidase; cryptic; glycoside hydrolase family protein 2099541 6064701 EcolC_1898 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001724873.1 2098189 D 481805 CDS YP_001724874.1 170019920 6064628 2099554..2100303 1 NC_010468.1 PFAM: YdjC family protein; KEGG: ssn:SSON_1425 hypothetical protein; hypothetical protein 2100303 6064628 EcolC_1899 Escherichia coli ATCC 8739 hypothetical protein YP_001724874.1 2099554 D 481805 CDS YP_001724875.1 170019921 6064602 complement(2100561..2102822) 1 NC_010468.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2102822 katE 6064602 katE Escherichia coli ATCC 8739 hydroperoxidase II YP_001724875.1 2100561 R 481805 CDS YP_001724876.1 170019922 6064597 2103005..2103268 1 NC_010468.1 KEGG: ssn:SSON_1427 hypothetical protein; cell division modulator 2103268 6064597 EcolC_1901 Escherichia coli ATCC 8739 cell division modulator YP_001724876.1 2103005 D 481805 CDS YP_001724877.1 170019923 6064588 2103557..2104339 1 NC_010468.1 KEGG: sfl:SF1498 hypothetical protein; hypothetical protein 2104339 6064588 EcolC_1902 Escherichia coli ATCC 8739 hypothetical protein YP_001724877.1 2103557 D 481805 CDS YP_001724878.1 170019924 6064583 complement(2104364..2105755) 1 NC_010468.1 PFAM: sodium:dicarboxylate symporter; KEGG: sbo:SBO_1361 kinase fragment; sodium:dicarboxylate symporter 2105755 6064583 EcolC_1903 Escherichia coli ATCC 8739 sodium:dicarboxylate symporter YP_001724878.1 2104364 R 481805 CDS YP_001724879.1 170019925 6064572 complement(2105888..2106478) 1 NC_010468.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: sdy:SDY_1821 hypothetical protein; hypothetical protein 2106478 6064572 EcolC_1904 Escherichia coli ATCC 8739 hypothetical protein YP_001724879.1 2105888 R 481805 CDS YP_001724880.1 170019926 6064553 complement(2106641..2107309) 1 NC_010468.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2107309 6064553 EcolC_1905 Escherichia coli ATCC 8739 2-deoxyglucose-6-phosphatase YP_001724880.1 2106641 R 481805 CDS YP_001724881.1 170019927 6064536 2107456..2107992 1 NC_010468.1 KEGG: sdy:SDY_1819 hypothetical protein; hypothetical protein 2107992 6064536 EcolC_1906 Escherichia coli ATCC 8739 hypothetical protein YP_001724881.1 2107456 D 481805 CDS YP_001724882.1 170019928 6064492 complement(2108033..2108893) 1 NC_010468.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: sdy:SDY_1818 hypothetical protein; fructosamine kinase 2108893 6064492 EcolC_1907 Escherichia coli ATCC 8739 fructosamine kinase YP_001724882.1 2108033 R 481805 CDS YP_001724883.1 170019929 6064479 complement(2108999..2109289) 1 NC_010468.1 KEGG: sdy:SDY_1817 hypothetical protein; hypothetical protein 2109289 6064479 EcolC_1908 Escherichia coli ATCC 8739 hypothetical protein YP_001724883.1 2108999 R 481805 CDS YP_001724884.1 170019930 6064467 complement(2109390..2110319) 1 NC_010468.1 TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: sbo:SBO_1367 6-phosphofructokinase II; 6-phosphofructokinase 2110319 6064467 EcolC_1909 Escherichia coli ATCC 8739 6-phosphofructokinase YP_001724884.1 2109390 R 481805 CDS YP_001724885.1 170019931 6067631 2110606..2111364 1 NC_010468.1 PFAM: protein of unknown function DUF481; KEGG: ssn:SSON_1435 hypothetical protein; hypothetical protein 2111364 6067631 EcolC_1910 Escherichia coli ATCC 8739 hypothetical protein YP_001724885.1 2110606 D 481805 CDS YP_001724886.1 170019932 6066916 2114119..2116047 1 NC_010468.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 2116047 6066916 EcolC_1913 Escherichia coli ATCC 8739 threonyl-tRNA synthetase YP_001724886.1 2114119 D 481805 CDS YP_001724887.1 170019933 6066921 2116051..2116593 1 NC_010468.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2116593 infC 6066921 infC Escherichia coli ATCC 8739 translation initiation factor IF-3 YP_001724887.1 2116051 D 481805 CDS YP_001724888.1 170019934 6068730 2116690..2116887 1 NC_010468.1 PFAM: ribosomal protein L35; KEGG: kpn:KPN_02178 50S ribosomal protein L35; 50S ribosomal protein L35 2116887 rpmI 6068730 rpmI Escherichia coli ATCC 8739 50S ribosomal protein L35 YP_001724888.1 2116690 D 481805 CDS YP_001724889.1 170019935 6068726 2116940..2117296 1 NC_010468.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2117296 rplT 6068726 rplT Escherichia coli ATCC 8739 50S ribosomal protein L20 YP_001724889.1 2116940 D 481805 CDS YP_001724890.1 170019936 6068722 2117747..2118730 1 NC_010468.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2118730 pheS 6068722 pheS Escherichia coli ATCC 8739 phenylalanyl-tRNA synthetase subunit alpha YP_001724890.1 2117747 D 481805 CDS YP_001724891.1 170019937 6068711 2118745..2121132 1 NC_010468.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2121132 pheT 6068711 pheT Escherichia coli ATCC 8739 phenylalanyl-tRNA synthetase subunit beta YP_001724891.1 2118745 D 481805 CDS YP_001724892.1 170019938 6068707 2121137..2121436 1 NC_010468.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 2121436 ihfA 6068707 ihfA Escherichia coli ATCC 8739 integration host factor subunit alpha YP_001724892.1 2121137 D 481805 CDS YP_001724893.1 170019939 6068697 2121537..2122517 1 NC_010468.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 2122517 6068697 EcolC_1920 Escherichia coli ATCC 8739 vtamin B12-transporter permease YP_001724893.1 2121537 D 481805 CDS YP_001724894.1 170019940 6068691 2122580..2123131 1 NC_010468.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase 2123131 btuE 6068691 btuE Escherichia coli ATCC 8739 putative glutathione peroxidase YP_001724894.1 2122580 D 481805 CDS YP_001724895.1 170019941 6068687 2123131..2123880 1 NC_010468.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 2123880 6068687 EcolC_1922 Escherichia coli ATCC 8739 vitamin B12-transporter ATPase YP_001724895.1 2123131 D 481805 CDS YP_001724896.1 170019942 6068683 2123958..2124422 1 NC_010468.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_1450 lipoprotein; NLP/P60 protein 2124422 6068683 EcolC_1923 Escherichia coli ATCC 8739 NLP/P60 protein YP_001724896.1 2123958 D 481805 CDS YP_001724897.1 170019943 6068679 2124669..2125382 1 NC_010468.1 KEGG: sbo:SBO_1421 hypothetical protein; putative diguanylate phosphodiesterase 2125382 6068679 EcolC_1924 Escherichia coli ATCC 8739 putative diguanylate phosphodiesterase YP_001724897.1 2124669 D 481805 CDS YP_001724898.1 170019944 6068667 2125445..2126881 1 NC_010468.1 PFAM: protein of unknown function UPF0061; KEGG: sbo:SBO_1422 hypothetical protein; hypothetical protein 2126881 6068667 EcolC_1925 Escherichia coli ATCC 8739 hypothetical protein YP_001724898.1 2125445 D 481805 CDS YP_001724899.1 170019945 6068664 complement(2126885..2127076) 1 NC_010468.1 KEGG: sbo:SBO_1423 hypothetical protein; hypothetical protein 2127076 6068664 EcolC_1926 Escherichia coli ATCC 8739 hypothetical protein YP_001724899.1 2126885 R 481805 CDS YP_001724900.1 170019946 6068660 complement(2127208..2128254) 1 NC_010468.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2128254 6068660 EcolC_1927 Escherichia coli ATCC 8739 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001724900.1 2127208 R 481805 CDS YP_001724901.1 170019947 6068648 complement(2128411..2129244) 1 NC_010468.1 PFAM: protein of unknown function DUF299; KEGG: sdy:SDY_1797 hypothetical protein; hypothetical protein 2129244 6068648 EcolC_1928 Escherichia coli ATCC 8739 hypothetical protein YP_001724901.1 2128411 R 481805 CDS YP_001724902.1 170019948 6068640 2129577..2131955 1 NC_010468.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 2131955 6068640 EcolC_1929 Escherichia coli ATCC 8739 phosphoenolpyruvate synthase YP_001724902.1 2129577 D 481805 CDS YP_001724903.1 170019949 6068623 complement(2132012..2133658) 1 NC_010468.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 2133658 6068623 EcolC_1930 Escherichia coli ATCC 8739 short chain acyl-CoA synthetase YP_001724903.1 2132012 R 481805 CDS YP_001724904.1 170019950 6068612 complement(2133715..2134008) 1 NC_010468.1 KEGG: sbo:SBO_1431 hypothetical protein; hypothetical protein 2134008 6068612 EcolC_1931 Escherichia coli ATCC 8739 hypothetical protein YP_001724904.1 2133715 R 481805 CDS YP_001724905.1 170019951 6068607 complement(2134005..2135294) 1 NC_010468.1 PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sfv:SFV_1525 probable electron transfer flavoprotein-quinone oxidoreductase YdiS; hypothetical protein 2135294 6068607 EcolC_1932 Escherichia coli ATCC 8739 hypothetical protein YP_001724905.1 2134005 R 481805 CDS YP_001724906.1 170019952 6068590 complement(2135350..2136288) 1 NC_010468.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2136288 6068590 EcolC_1933 Escherichia coli ATCC 8739 electron transfer flavoprotein subunit YdiR YP_001724906.1 2135350 R 481805 CDS YP_001724907.1 170019953 6068581 complement(2136308..2137072) 1 NC_010468.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 2137072 6068581 EcolC_1934 Escherichia coli ATCC 8739 putative electron transfer flavoprotein YdiQ YP_001724907.1 2136308 R 481805 CDS YP_001724908.1 170019954 6068575 2137388..2138299 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; KEGG: sbo:SBO_1435 putative AraC-type regulatory protein; AraC family transcriptional regulator 2138299 6068575 EcolC_1935 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001724908.1 2137388 D 481805 CDS YP_001724909.1 170019955 6068573 complement(2138342..2139493) 1 NC_010468.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 2139493 6068573 EcolC_1936 Escherichia coli ATCC 8739 putative acyl-CoA dehydrogenase YP_001724909.1 2138342 R 481805 CDS YP_001724910.1 170019956 6068569 complement(2139507..2141102) 1 NC_010468.1 PFAM: coenzyme A transferase; KEGG: stm:STM1357.S putative acetyl-CoA/acetoacetyl-CoA transferase beta subunit; coenzyme A transferase 2141102 6068569 EcolC_1937 Escherichia coli ATCC 8739 coenzyme A transferase YP_001724910.1 2139507 R 481805 CDS YP_001724911.1 170019957 6068561 complement(2141247..2142005) 1 NC_010468.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2142005 aroD 6068561 aroD Escherichia coli ATCC 8739 3-dehydroquinate dehydratase YP_001724911.1 2141247 R 481805 CDS YP_001724912.1 170019958 6068553 complement(2142036..2142902) 1 NC_010468.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2142902 6068553 EcolC_1939 Escherichia coli ATCC 8739 quinate/shikimate dehydrogenase YP_001724912.1 2142036 R 481805 CDS YP_001724913.1 170019959 6068548 complement(2142914..2144179) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1463 putative amino acid/amine transport protein; major facilitator transporter 2144179 6068548 EcolC_1940 Escherichia coli ATCC 8739 major facilitator transporter YP_001724913.1 2142914 R 481805 CDS YP_001724914.1 170019960 6068542 complement(2144406..2145620) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S1852 putative transport system permease protein; major facilitator transporter 2145620 6068542 EcolC_1941 Escherichia coli ATCC 8739 major facilitator transporter YP_001724914.1 2144406 R 481805 CDS YP_001724915.1 170019961 6068540 complement(2145720..2146076) 1 NC_010468.1 PFAM: Domain of unknown function DUF1870; KEGG: ssn:SSON_1466 hypothetical protein; hypothetical protein 2146076 6068540 EcolC_1942 Escherichia coli ATCC 8739 hypothetical protein YP_001724915.1 2145720 R 481805 CDS YP_001724916.1 170019962 6068531 complement(2146505..2147617) 1 NC_010468.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 2147617 6068531 EcolC_1943 Escherichia coli ATCC 8739 putative inner membrane protein YP_001724916.1 2146505 R 481805 CDS YP_001724917.1 170019963 6068527 2148006..2151062 1 NC_010468.1 PFAM: FAD linked oxidase domain protein; KEGG: ssn:SSON_1469 putative oxidase; FAD linked oxidase domain-containing protein 2151062 6068527 EcolC_1944 Escherichia coli ATCC 8739 FAD linked oxidase domain-containing protein YP_001724917.1 2148006 D 481805 CDS YP_001724918.1 170019964 6068521 2151059..2151469 1 NC_010468.1 PFAM: thioesterase superfamily protein; KEGG: sbo:SBO_1444 hypothetical protein; hypothetical protein 2151469 6068521 EcolC_1945 Escherichia coli ATCC 8739 hypothetical protein YP_001724918.1 2151059 D 481805 CDS YP_001724919.1 170019965 6068503 2151569..2151757 1 NC_010468.1 KEGG: sbo:SBO_1445 hypothetical protein; hypothetical protein 2151757 6068503 EcolC_1946 Escherichia coli ATCC 8739 hypothetical protein YP_001724919.1 2151569 D 481805 CDS YP_001724920.1 170019966 6068489 2152305..2152673 1 NC_010468.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 2152673 sufA 6068489 sufA Escherichia coli ATCC 8739 iron-sulfur cluster assembly scaffold protein YP_001724920.1 2152305 D 481805 CDS YP_001724921.1 170019967 6068473 2152682..2154169 1 NC_010468.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 2154169 6068473 EcolC_1948 Escherichia coli ATCC 8739 cysteine desulfurase activator complex subunit SufB YP_001724921.1 2152682 D 481805 CDS YP_001724922.1 170019968 6068461 2154179..2154925 1 NC_010468.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 2154925 sufC 6068461 sufC Escherichia coli ATCC 8739 cysteine desulfurase YP_001724922.1 2154179 D 481805 CDS YP_001724923.1 170019969 6068456 2154900..2156171 1 NC_010468.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 2156171 6068456 EcolC_1950 Escherichia coli ATCC 8739 cysteine desulfurase activator complex subunit SufD YP_001724923.1 2154900 D 481805 CDS YP_001724924.1 170019970 6068450 2156168..2157388 1 NC_010468.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 2157388 6068450 EcolC_1951 Escherichia coli ATCC 8739 bifunctional cysteine desulfurase/selenocysteine lyase YP_001724924.1 2156168 D 481805 CDS YP_001724925.1 170019971 6068437 2157401..2157817 1 NC_010468.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 2157817 6068437 EcolC_1952 Escherichia coli ATCC 8739 cysteine desufuration protein SufE YP_001724925.1 2157401 D 481805 CDS YP_001724926.1 170019972 6068429 2157966..2158970 1 NC_010468.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sfv:SFV_1701 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 2158970 6068429 EcolC_1953 Escherichia coli ATCC 8739 ErfK/YbiS/YcfS/YnhG family protein YP_001724926.1 2157966 D 481805 CDS YP_001724927.1 170019973 6068422 complement(2159034..2159270) 1 NC_010468.1 PFAM: LPP repeat-containing protein; KEGG: sdy:SDY_1908 murein lipoprotein; LPP repeat-containing protein 2159270 6068422 EcolC_1954 Escherichia coli ATCC 8739 LPP repeat-containing protein YP_001724927.1 2159034 R 481805 CDS YP_001724928.1 170019974 6068415 complement(2159581..2160993) 1 NC_010468.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2160993 6068415 EcolC_1955 Escherichia coli ATCC 8739 pyruvate kinase YP_001724928.1 2159581 R 481805 CDS YP_001724929.1 170019975 6068396 2161550..2161759 1 NC_010468.1 KEGG: sdy:SDY_1904 hypothetical protein; hypothetical protein 2161759 6068396 EcolC_1956 Escherichia coli ATCC 8739 hypothetical protein YP_001724929.1 2161550 D 481805 CDS YP_001724930.1 170019976 6068391 2162214..2162840 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_1458 putative oxidoreductase, Fe-S subunit; hypothetical protein 2162840 6068391 EcolC_1957 Escherichia coli ATCC 8739 hypothetical protein YP_001724930.1 2162214 D 481805 CDS YP_001724931.1 170019977 6068384 2162861..2164963 1 NC_010468.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: sbo:SBO_1459 hypothetical protein; putative oxidoreductase 2164963 6068384 EcolC_1958 Escherichia coli ATCC 8739 putative oxidoreductase YP_001724931.1 2162861 D 481805 CDS YP_001724932.1 170019978 6068361 2164976..2165614 1 NC_010468.1 KEGG: sbo:SBO_1460 hypothetical protein; hypothetical protein 2165614 6068361 EcolC_1959 Escherichia coli ATCC 8739 hypothetical protein YP_001724932.1 2164976 D 481805 CDS YP_001724933.1 170019979 6068339 2165678..2166346 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1899 putative oxidoreductase, Fe-S subunit; 4Fe-4S ferredoxin 2166346 6068339 EcolC_1960 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001724933.1 2165678 D 481805 CDS YP_001724934.1 170019980 6068333 2166343..2167128 1 NC_010468.1 PFAM: cytochrome B561; KEGG: sbo:SBO_1462 hypothetical protein; cytochrome B561 2167128 6068333 EcolC_1961 Escherichia coli ATCC 8739 cytochrome B561 YP_001724934.1 2166343 D 481805 CDS YP_001724935.1 170019981 6068326 2167180..2167944 1 NC_010468.1 KEGG: ssn:SSON_1487 hypothetical protein; hypothetical protein 2167944 6068326 EcolC_1962 Escherichia coli ATCC 8739 hypothetical protein YP_001724935.1 2167180 D 481805 CDS YP_001724936.1 170019982 6068321 complement(2167956..2169560) 1 NC_010468.1 KEGG: sbo:SBO_1464 hypothetical protein; hypothetical protein 2169560 6068321 EcolC_1963 Escherichia coli ATCC 8739 hypothetical protein YP_001724936.1 2167956 R 481805 CDS YP_001724937.1 170019983 6068316 complement(2169686..2169991) 1 NC_010468.1 PFAM: Putative mono-oxygenase ydhR; KEGG: sbo:SBO_1465 hypothetical protein; hypothetical protein 2169991 6068316 EcolC_1964 Escherichia coli ATCC 8739 hypothetical protein YP_001724937.1 2169686 R 481805 CDS YP_001724938.1 170019984 6068271 2170564..2171820 1 NC_010468.1 KEGG: sdy:SDY_1891 possible enzyme; hypothetical protein 2171820 6068271 EcolC_1965 Escherichia coli ATCC 8739 hypothetical protein YP_001724938.1 2170564 D 481805 CDS YP_001724939.1 170019985 6068252 complement(2171861..2173234) 1 NC_010468.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 2173234 6068252 EcolC_1966 Escherichia coli ATCC 8739 multidrug efflux protein YP_001724939.1 2171861 R 481805 CDS YP_001724940.1 170019986 6068242 2173449..2174090 1 NC_010468.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2174090 6068242 EcolC_1967 Escherichia coli ATCC 8739 riboflavin synthase subunit alpha YP_001724940.1 2173449 D 481805 CDS YP_001724941.1 170019987 6068237 complement(2174130..2175278) 1 NC_010468.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 2175278 6068237 EcolC_1968 Escherichia coli ATCC 8739 cyclopropane-fatty-acyl-phospholipid synthase YP_001724941.1 2174130 R 481805 CDS YP_001724942.1 170019988 6068231 complement(2175569..2176780) 1 NC_010468.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2176780 6068231 EcolC_1969 Escherichia coli ATCC 8739 inner membrane transport protein YdhC YP_001724942.1 2175569 R 481805 CDS YP_001724943.1 170019989 6068223 2176893..2177825 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1472 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 2177825 6068223 EcolC_1970 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001724943.1 2176893 D 481805 CDS YP_001724944.1 170019990 6068221 complement(2177822..2178847) 1 NC_010468.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 2178847 6068221 EcolC_1971 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor PurR YP_001724944.1 2177822 R 481805 CDS YP_001724945.1 170019991 6068217 2179401..2180570 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_1883 putative transport protein; major facilitator transporter 2180570 6068217 EcolC_1972 Escherichia coli ATCC 8739 major facilitator transporter YP_001724945.1 2179401 D 481805 CDS YP_001724946.1 170019992 6068213 complement(2180716..2181297) 1 NC_010468.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 2181297 6068213 EcolC_1973 Escherichia coli ATCC 8739 superoxide dismutase YP_001724946.1 2180716 R 481805 CDS YP_001724947.1 170019993 6068208 complement(2181425..2182240) 1 NC_010468.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_1501 putative lipoprotein; NLP/P60 protein 2182240 6068208 EcolC_1974 Escherichia coli ATCC 8739 NLP/P60 protein YP_001724947.1 2181425 R 481805 CDS YP_001724948.1 170019994 6068204 2182574..2182921 1 NC_010468.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sdy:SDY_1880 hypothetical protein; hypothetical protein 2182921 6068204 EcolC_1975 Escherichia coli ATCC 8739 hypothetical protein YP_001724948.1 2182574 D 481805 CDS YP_001724949.1 170019995 6068201 complement(2182972..2187588) 1 NC_010468.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 2187588 6068201 EcolC_1976 Escherichia coli ATCC 8739 putative ATP-dependent helicase Lhr YP_001724949.1 2182972 R 481805 CDS YP_001724950.1 170019996 6068199 complement(2187681..2188328) 1 NC_010468.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2188328 6068199 EcolC_1977 Escherichia coli ATCC 8739 ribonuclease T YP_001724950.1 2187681 R 481805 CDS YP_001724951.1 170019997 6068195 complement(2188431..2188838) 1 NC_010468.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 2188838 6068195 EcolC_1978 Escherichia coli ATCC 8739 glyoxalase I YP_001724951.1 2188431 R 481805 CDS YP_001724952.1 170019998 6068191 complement(2188919..2190016) 1 NC_010468.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 2190016 6068191 EcolC_1979 Escherichia coli ATCC 8739 N-ethylmaleimide reductase YP_001724952.1 2188919 R 481805 CDS YP_001724953.1 170019999 6068189 complement(2190053..2190652) 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: sbo:SBO_1487 hypothetical protein; TetR family transcriptional regulator 2190652 6068189 EcolC_1980 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001724953.1 2190053 R 481805 CDS YP_001724954.1 170020000 6068185 2190755..2190994 1 NC_010468.1 PFAM: protein of unknown function DUF1289; KEGG: sdy:SDY_1873 hypothetical protein; hypothetical protein 2190994 6068185 EcolC_1981 Escherichia coli ATCC 8739 hypothetical protein YP_001724954.1 2190755 D 481805 CDS YP_001724955.1 170020001 6068183 2191043..2191939 1 NC_010468.1 PFAM: aldo/keto reductase; KEGG: ssn:SSON_1509 hypothetical protein; aldo/keto reductase 2191939 6068183 EcolC_1982 Escherichia coli ATCC 8739 aldo/keto reductase YP_001724955.1 2191043 D 481805 CDS YP_001724956.1 170020002 6068179 2192005..2192541 1 NC_010468.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 2192541 6068179 EcolC_1983 Escherichia coli ATCC 8739 superoxide dismutase YP_001724956.1 2192005 D 481805 CDS YP_001724957.1 170020003 6068177 complement(2192542..2194554) 1 NC_010468.1 PFAM: Fusaric acid resistance protein conserved region; KEGG: ssn:SSON_1511 hypothetical protein; fusaric acid resistance protein 2194554 6068177 EcolC_1984 Escherichia coli ATCC 8739 fusaric acid resistance protein YP_001724957.1 2192542 R 481805 CDS YP_001724958.1 170020004 6068174 complement(2194554..2195411) 1 NC_010468.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_1663 hypothetical protein; secretion protein HlyD family protein 2195411 6068174 EcolC_1985 Escherichia coli ATCC 8739 secretion protein HlyD family protein YP_001724958.1 2194554 R 481805 CDS YP_001724959.1 170020005 6068170 complement(2195414..2195641) 1 NC_010468.1 PFAM: protein of unknown function DUF1656; KEGG: ssn:SSON_1513 hypothetical protein; hypothetical protein 2195641 6068170 EcolC_1986 Escherichia coli ATCC 8739 hypothetical protein YP_001724959.1 2195414 R 481805 CDS YP_001724960.1 170020006 6068167 2195845..2196285 1 NC_010468.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 2196285 6068167 EcolC_1987 Escherichia coli ATCC 8739 transcriptional regulator SlyA YP_001724960.1 2195845 D 481805 CDS YP_001724961.1 170020007 6068165 complement(2196332..2196799) 1 NC_010468.1 PFAM: 17 kDa surface antigen; KEGG: sdy:SDY_1864 putative outer membrane protein; 17 kDa surface antigen 2196799 6068165 EcolC_1988 Escherichia coli ATCC 8739 17 kDa surface antigen YP_001724961.1 2196332 R 481805 CDS YP_001724962.1 170020008 6068163 2197073..2198182 1 NC_010468.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 2198182 anmK 6068163 anmK Escherichia coli ATCC 8739 anhydro-N-acetylmuramic acid kinase YP_001724962.1 2197073 D 481805 CDS YP_001724963.1 170020009 6068160 2198286..2198609 1 NC_010468.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 2198609 6068160 EcolC_1990 Escherichia coli ATCC 8739 lysozyme inhibitor YP_001724963.1 2198286 D 481805 CDS YP_001724964.1 170020010 6068157 2198668..2199324 1 NC_010468.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2199324 6068157 EcolC_1991 Escherichia coli ATCC 8739 pyridoxamine 5'-phosphate oxidase YP_001724964.1 2198668 D 481805 CDS YP_001724965.1 170020011 6068155 2199453..2200727 1 NC_010468.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2200727 6068155 EcolC_1992 Escherichia coli ATCC 8739 tyrosyl-tRNA synthetase YP_001724965.1 2199453 D 481805 CDS YP_001724966.1 170020012 6068151 2200789..2201649 1 NC_010468.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 2201649 6068151 EcolC_1993 Escherichia coli ATCC 8739 pyridoxamine kinase YP_001724966.1 2200789 D 481805 CDS YP_001724967.1 170020013 6068148 complement(2201693..2202298) 1 NC_010468.1 PFAM: Glutathione S-transferase domain; KEGG: sdy:SDY_1858 glutathionine S-transferase; glutathionine S-transferase 2202298 6068148 EcolC_1994 Escherichia coli ATCC 8739 glutathionine S-transferase YP_001724967.1 2201693 R 481805 CDS YP_001724968.1 170020014 6068146 complement(2202404..2203906) 1 NC_010468.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 2203906 tppB 6068146 tppB Escherichia coli ATCC 8739 putative tripeptide transporter permease YP_001724968.1 2202404 R 481805 CDS YP_001724969.1 170020015 6068144 complement(2204517..2205152) 1 NC_010468.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 2205152 6068144 EcolC_1996 Escherichia coli ATCC 8739 endonuclease III YP_001724969.1 2204517 R 481805 CDS YP_001724970.1 170020016 6068141 complement(2205152..2205847) 1 NC_010468.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 2205847 6068141 EcolC_1997 Escherichia coli ATCC 8739 electron transport complex protein RsxE YP_001724970.1 2205152 R 481805 CDS YP_001724971.1 170020017 6068138 complement(2205851..2206471) 1 NC_010468.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 2206471 6068138 EcolC_1998 Escherichia coli ATCC 8739 electron transport complex protein RnfG YP_001724971.1 2205851 R 481805 CDS YP_001724972.1 170020018 6068135 complement(2206475..2207533) 1 NC_010468.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 2207533 rnfD 6068135 rnfD Escherichia coli ATCC 8739 electron transport complex protein RnfD YP_001724972.1 2206475 R 481805 CDS YP_001724973.1 170020019 6068133 complement(2207534..2209756) 1 NC_010468.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 2209756 6068133 EcolC_2000 Escherichia coli ATCC 8739 electron transport complex protein RnfC YP_001724973.1 2207534 R 481805 CDS YP_001724974.1 170020020 6068125 complement(2209749..2210327) 1 NC_010468.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 2210327 6068125 EcolC_2001 Escherichia coli ATCC 8739 electron transport complex protein RnfB YP_001724974.1 2209749 R 481805 CDS YP_001724975.1 170020021 6068122 complement(2210327..2210908) 1 NC_010468.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: sdy:SDY_1850 hypothetical protein; Na(+)-translocating NADH-quinone reductase subunit E 2210908 6068122 EcolC_2002 Escherichia coli ATCC 8739 Na(+)-translocating NADH-quinone reductase subunit E YP_001724975.1 2210327 R 481805 CDS YP_001724976.1 170020022 6068118 complement(2210985..2211425) 1 NC_010468.1 KEGG: ssn:SSON_1532 hypothetical protein; hypothetical protein 2211425 6068118 EcolC_2003 Escherichia coli ATCC 8739 hypothetical protein YP_001724976.1 2210985 R 481805 CDS YP_001724977.1 170020023 6068113 complement(2211511..2211726) 1 NC_010468.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 2211726 6068113 EcolC_2004 Escherichia coli ATCC 8739 oriC-binding nucleoid-associated protein YP_001724977.1 2211511 R 481805 CDS YP_001724978.1 170020024 6068104 complement(2211999..2212124) 1 NC_010468.1 KEGG: cko:CKO_01632 hypothetical protein; hypothetical protein 2212124 6068104 EcolC_2005 Escherichia coli ATCC 8739 hypothetical protein YP_001724978.1 2211999 R 481805 CDS YP_001724979.1 170020025 6068085 2212367..2213407 1 NC_010468.1 PFAM: Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain protein; Oxidoreductase domain; KEGG: sbo:SBO_1510 hypothetical protein; putative oxidoreductase 2213407 6068085 EcolC_2006 Escherichia coli ATCC 8739 putative oxidoreductase YP_001724979.1 2212367 D 481805 CDS YP_001724980.1 170020026 6068080 complement(2213441..2214442) 1 NC_010468.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 2214442 6068080 EcolC_2007 Escherichia coli ATCC 8739 adenosine deaminase YP_001724980.1 2213441 R 481805 CDS YP_001724981.1 170020027 6068075 complement(2214546..2215718) 1 NC_010468.1 PFAM: aminotransferase class I and II; KEGG: sbo:SBO_1512 MalY; class I and II aminotransferase 2215718 6068075 EcolC_2008 Escherichia coli ATCC 8739 class I and II aminotransferase YP_001724981.1 2214546 R 481805 CDS YP_001724982.1 170020028 6068064 2217494..2218522 1 NC_010468.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 2218522 6068064 EcolC_2010 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor MalI YP_001724982.1 2217494 D 481805 CDS YP_001724983.1 170020029 6068056 2218634..2219401 1 NC_010468.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 2219401 6068056 EcolC_2011 Escherichia coli ATCC 8739 7-alpha-hydroxysteroid dehydrogenase YP_001724983.1 2218634 D 481805 CDS YP_001724984.1 170020030 6068052 2219622..2220212 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: sdy:SDY_1837 repressor for uid operon; TetR family transcriptional regulator 2220212 6068052 EcolC_2012 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001724984.1 2219622 D 481805 CDS YP_001724985.1 170020031 6068046 2220603..2222414 1 NC_010468.1 PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: ssn:SSON_1543 beta-D-glucuronidase; beta-D-glucuronidase 2222414 6068046 EcolC_2013 Escherichia coli ATCC 8739 beta-D-glucuronidase YP_001724985.1 2220603 D 481805 CDS YP_001724986.1 170020032 6068033 2223822..2225087 1 NC_010468.1 KEGG: ssn:SSON_1545 membrane-associated protein; putative outer membrane porin protein 2225087 6068033 EcolC_2015 Escherichia coli ATCC 8739 putative outer membrane porin protein YP_001724986.1 2223822 D 481805 CDS YP_001724987.1 170020033 6068021 complement(2225132..2226640) 1 NC_010468.1 PFAM: protein of unknown function DUF945; KEGG: ssn:SSON_1546 hypothetical protein; hypothetical protein 2226640 6068021 EcolC_2016 Escherichia coli ATCC 8739 hypothetical protein YP_001724987.1 2225132 R 481805 CDS YP_001724988.1 170020034 6068008 complement(2226741..2227916) 1 NC_010468.1 KEGG: sbo:SBO_1523 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; mannose-6-phosphate isomerase 2227916 6068008 EcolC_2017 Escherichia coli ATCC 8739 mannose-6-phosphate isomerase YP_001724988.1 2226741 R 481805 CDS YP_001724989.1 170020035 6068000 2228115..2229761 1 NC_010468.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sbo:SBO_1524 fumarase A; tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta 2229761 6068000 EcolC_2018 Escherichia coli ATCC 8739 tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta YP_001724989.1 2228115 D 481805 CDS YP_001724990.1 170020036 6067990 2229904..2231307 1 NC_010468.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 2231307 fumC 6067990 fumC Escherichia coli ATCC 8739 fumarate hydratase YP_001724990.1 2229904 D 481805 CDS YP_001724991.1 170020037 6067979 complement(2231304..2232233) 1 NC_010468.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 2232233 6067979 EcolC_2020 Escherichia coli ATCC 8739 DNA replication terminus site-binding protein YP_001724991.1 2231304 R 481805 CDS YP_001724992.1 170020038 6067965 complement(2232309..2233610) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_1825 sensor histidine protein kinase; sensor protein RstB 2233610 6067965 EcolC_2021 Escherichia coli ATCC 8739 sensor protein RstB YP_001724992.1 2232309 R 481805 CDS YP_001724993.1 170020039 6067954 complement(2233614..2234333) 1 NC_010468.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 2234333 6067954 EcolC_2022 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator RstA YP_001724993.1 2233614 R 481805 CDS YP_001724994.1 170020040 6067950 2234462..2234797 1 NC_010468.1 PFAM: GlpM family protein; KEGG: sdy:SDY_1546 hypothetical protein; GlpM family protein 2234797 6067950 EcolC_2023 Escherichia coli ATCC 8739 GlpM family protein YP_001724994.1 2234462 D 481805 CDS YP_001724995.1 170020041 6067941 complement(2234794..2235516) 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_1547 putative oxidoreductase; short chain dehydrogenase 2235516 6067941 EcolC_2024 Escherichia coli ATCC 8739 short chain dehydrogenase YP_001724995.1 2234794 R 481805 CDS YP_001724996.1 170020042 6067938 complement(2235553..2236935) 1 NC_010468.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: sfv:SFV_1620 putative arginine/ornithine antiporter; arginine/ornithine antiporter 2236935 6067938 EcolC_2025 Escherichia coli ATCC 8739 arginine/ornithine antiporter YP_001724996.1 2235553 R 481805 CDS YP_001724997.1 170020043 6067921 complement(2237121..2238065) 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: sdy:SDY_1549 hypothetical protein; hypothetical protein 2238065 6067921 EcolC_2026 Escherichia coli ATCC 8739 hypothetical protein YP_001724997.1 2237121 R 481805 CDS YP_001724998.1 170020044 6067915 2238589..2240121 1 NC_010468.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 2240121 pntA 6067915 pntA Escherichia coli ATCC 8739 NAD(P) transhydrogenase subunit alpha YP_001724998.1 2238589 D 481805 CDS YP_001724999.1 170020045 6067913 2240132..2241520 1 NC_010468.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 2241520 pntB 6067913 pntB Escherichia coli ATCC 8739 pyridine nucleotide transhydrogenase YP_001724999.1 2240132 D 481805 CDS YP_001725000.1 170020046 6067906 complement(2241545..2242579) 1 NC_010468.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 2242579 tqsA 6067906 tqsA Escherichia coli ATCC 8739 putative transport protein YP_001725000.1 2241545 R 481805 CDS YP_001725001.1 170020047 6067898 2242991..2243356 1 NC_010468.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 2243356 6067898 EcolC_2030 Escherichia coli ATCC 8739 multidrug efflux system protein MdtJ YP_001725001.1 2242991 D 481805 CDS YP_001725002.1 170020048 6067886 2243343..2243672 1 NC_010468.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 2243672 6067886 EcolC_2031 Escherichia coli ATCC 8739 multidrug efflux system protein MdtI YP_001725002.1 2243343 D 481805 CDS YP_001725003.1 170020049 6067881 complement(2243711..2244532) 1 NC_010468.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: sfv:SFV_1613 hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap 2244532 6067881 EcolC_2032 Escherichia coli ATCC 8739 peptidase S1 and S6 chymotrypsin/Hap YP_001725003.1 2243711 R 481805 CDS YP_001725004.1 170020050 6067873 complement(2244808..2245116) 1 NC_010468.1 required for growth and survival under moderately acid conditions; acid shock protein 2245116 6067873 EcolC_2033 Escherichia coli ATCC 8739 acid shock protein YP_001725004.1 2244808 R 481805 CDS YP_001725005.1 170020051 6067867 complement(2245540..2246793) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1568 putative transport protein; major facilitator transporter 2246793 6067867 EcolC_2034 Escherichia coli ATCC 8739 major facilitator transporter YP_001725005.1 2245540 R 481805 CDS YP_001725006.1 170020052 6067854 2246900..2247793 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1569 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2247793 6067854 EcolC_2035 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725006.1 2246900 D 481805 CDS YP_001725007.1 170020053 6067852 2247928..2249148 1 NC_010468.1 PFAM: ROK family protein; KEGG: ssn:SSON_1570 putative NAGC-like transcriptional regulator; ROK family protein 2249148 6067852 EcolC_2036 Escherichia coli ATCC 8739 ROK family protein YP_001725007.1 2247928 D 481805 CDS YP_001725008.1 170020054 6067850 2249273..2249968 1 NC_010468.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase 2249968 6067850 EcolC_2037 Escherichia coli ATCC 8739 putative dithiobiotin synthetase YP_001725008.1 2249273 D 481805 CDS YP_001725009.1 170020055 6067848 complement(2249921..2251177) 1 NC_010468.1 PFAM: Chloride channel core; KEGG: sbo:SBO_1544 putative chloride channel; putative voltage-gated ClC-type chloride channel ClcB 2251177 6067848 EcolC_2038 Escherichia coli ATCC 8739 putative voltage-gated ClC-type chloride channel ClcB YP_001725009.1 2249921 R 481805 CDS YP_001725010.1 170020056 6067841 complement(2251372..2251986) 1 NC_010468.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 2251986 6067841 EcolC_2039 Escherichia coli ATCC 8739 twin-argninine leader-binding protein DmsD YP_001725010.1 2251372 R 481805 CDS YP_001725011.1 170020057 6067833 complement(2252029..2252883) 1 NC_010468.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_1546 putative DMSO reductase anchor subunit; DMSO reductase anchor subunit DmsC 2252883 6067833 EcolC_2040 Escherichia coli ATCC 8739 DMSO reductase anchor subunit DmsC YP_001725011.1 2252029 R 481805 CDS YP_001725012.1 170020058 6067830 complement(2252885..2253502) 1 NC_010468.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1567 putative oxidoreductase, Fe-S subunit; dimethylsulfoxide reductase subunit B 2253502 6067830 EcolC_2041 Escherichia coli ATCC 8739 dimethylsulfoxide reductase subunit B YP_001725012.1 2252885 R 481805 CDS YP_001725013.1 170020059 6067817 complement(2253513..2255936) 1 NC_010468.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sbo:SBO_1548 putative oxidoreductase, major subunit; anaerobic dimethyl sulfoxide reductase subunit A 2255936 6067817 EcolC_2042 Escherichia coli ATCC 8739 anaerobic dimethyl sulfoxide reductase subunit A YP_001725013.1 2253513 R 481805 CDS YP_001725014.1 170020060 6067808 complement(2255997..2258423) 1 NC_010468.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: stm:STM1499 putative dimethyl sulphoxide reductase, chain A1; anaerobic dimethyl sulfoxide reductase subunit A 2258423 6067808 EcolC_2043 Escherichia coli ATCC 8739 anaerobic dimethyl sulfoxide reductase subunit A YP_001725014.1 2255997 R 481805 CDS YP_001725015.1 170020061 6067802 complement(2258622..2258927) 1 NC_010468.1 PFAM: protein of unknown function DUF1161; KEGG: sfv:SFV_1558 hypothetical protein; hypothetical protein 2258927 6067802 EcolC_2044 Escherichia coli ATCC 8739 hypothetical protein YP_001725015.1 2258622 R 481805 CDS YP_001725016.1 170020062 6067795 2258999..2259745 1 NC_010468.1 PFAM: protein of unknown function UPF0257; KEGG: sfv:SFV_1559 hypothetical protein; hypothetical protein 2259745 6067795 EcolC_2045 Escherichia coli ATCC 8739 hypothetical protein YP_001725016.1 2258999 D 481805 CDS YP_001725017.1 170020063 6067784 complement(2259748..2260308) 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cko:CKO_01578 hypothetical protein; N-acetyltransferase GCN5 2260308 6067784 EcolC_2046 Escherichia coli ATCC 8739 N-acetyltransferase GCN5 YP_001725017.1 2259748 R 481805 CDS YP_001725018.1 170020064 6067777 complement(2260343..2260684) 1 NC_010468.1 PFAM: protein of unknown function DUF1283; KEGG: sfv:SFV_1561 hypothetical protein; hypothetical protein 2260684 6067777 EcolC_2047 Escherichia coli ATCC 8739 hypothetical protein YP_001725018.1 2260343 R 481805 CDS YP_001725019.1 170020065 6067767 2260819..2261145 1 NC_010468.1 PFAM: protein of unknown function UPF0060; KEGG: sdy:SDY_1577 hypothetical protein; hypothetical protein 2261145 6067767 EcolC_2048 Escherichia coli ATCC 8739 hypothetical protein YP_001725019.1 2260819 D 481805 CDS YP_001725020.1 170020066 6067763 2261351..2262565 1 NC_010468.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sfx:S1718 starvation sensing protein; mandelate racemase/muconate lactonizing protein 2262565 6067763 EcolC_2049 Escherichia coli ATCC 8739 mandelate racemase/muconate lactonizing protein YP_001725020.1 2261351 D 481805 CDS YP_001725021.1 170020067 6067750 2262577..2263596 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cko:CKO_01574 hypothetical protein; putative dehydrogenase 2263596 6067750 EcolC_2050 Escherichia coli ATCC 8739 putative dehydrogenase YP_001725021.1 2262577 D 481805 CDS YP_001725022.1 170020068 6067747 2263654..2263764 1 NC_010468.1 KEGG: cko:CKO_01573 hypothetical protein; hypothetical protein 2263764 6067747 EcolC_2051 Escherichia coli ATCC 8739 hypothetical protein YP_001725022.1 2263654 D 481805 CDS YP_001725023.1 170020069 6067742 complement(2263784..2265079) 1 NC_010468.1 PFAM: integrase family protein; KEGG: stm:STM0893 putative integrase; integrase family protein 2265079 6067742 EcolC_2052 Escherichia coli ATCC 8739 integrase family protein YP_001725023.1 2263784 R 481805 CDS YP_001725024.1 170020070 6067728 complement(2265099..2265350) 1 NC_010468.1 PFAM: protein of unknown function DUF1233 excisionase putative; KEGG: esa:ESA_01609 hypothetical protein; hypothetical protein 2265350 6067728 EcolC_2053 Escherichia coli ATCC 8739 hypothetical protein YP_001725024.1 2265099 R 481805 CDS YP_001725025.1 170020071 6067715 complement(2265423..2267900) 1 NC_010468.1 PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: sbo:SBO_0976 putative exodeoxyribonuclease VIII; exonuclease RNase T and DNA polymerase III 2267900 6067715 EcolC_2054 Escherichia coli ATCC 8739 exonuclease RNase T and DNA polymerase III YP_001725025.1 2265423 R 481805 CDS YP_001725026.1 170020072 6067706 complement(2267993..2268184) 1 NC_010468.1 PFAM: protein of unknown function DUF1482; KEGG: cko:CKO_01911 hypothetical protein; hypothetical protein 2268184 6067706 EcolC_2055 Escherichia coli ATCC 8739 hypothetical protein YP_001725026.1 2267993 R 481805 CDS YP_001725027.1 170020073 6067689 complement(2268937..2269155) 1 NC_010468.1 hypothetical protein 2269155 6067689 EcolC_2056 Escherichia coli ATCC 8739 hypothetical protein YP_001725027.1 2268937 R 481805 CDS YP_001725028.1 170020074 6067683 complement(2269315..2269470) 1 NC_010468.1 PFAM: protein of unknown function DUF1391; KEGG: ssn:SSON_0728 hypothetical prophage protein; hypothetical protein 2269470 6067683 EcolC_2057 Escherichia coli ATCC 8739 hypothetical protein YP_001725028.1 2269315 R 481805 CDS YP_001725029.1 170020075 6067675 complement(2269637..2270044) 1 NC_010468.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 2270044 6067675 EcolC_2058 Escherichia coli ATCC 8739 transcriptional repressor DicA YP_001725029.1 2269637 R 481805 CDS YP_001725030.1 170020076 6067659 2270128..2270358 1 NC_010468.1 KEGG: sfv:SFV_0741 putative regulator of cell division encoded by prophage; DNA-binding transcriptional regulator DicC 2270358 6067659 EcolC_2059 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator DicC YP_001725030.1 2270128 D 481805 CDS YP_001725031.1 170020077 6067649 2270342..2270863 1 NC_010468.1 PFAM: protein of unknown function DUF1019; hypothetical protein 2270863 6067649 EcolC_2060 Escherichia coli ATCC 8739 hypothetical protein YP_001725031.1 2270342 D 481805 CDS YP_001725032.1 170020078 6067641 2270895..2271809 1 NC_010468.1 KEGG: ent:Ent638_2616 hypothetical protein; hypothetical protein 2271809 6067641 EcolC_2061 Escherichia coli ATCC 8739 hypothetical protein YP_001725032.1 2270895 D 481805 CDS YP_001725033.1 170020079 6067639 2271850..2272272 1 NC_010468.1 PFAM: protein of unknown function DUF977; KEGG: sbo:SBO_0970 putative bacteriophage protein; hypothetical protein 2272272 6067639 EcolC_2062 Escherichia coli ATCC 8739 hypothetical protein YP_001725033.1 2271850 D 481805 CDS YP_001725034.1 170020080 6067622 2272269..2272625 1 NC_010468.1 KEGG: ent:Ent638_1018 putative methyltransferase; putative methyltransferase 2272625 6067622 EcolC_2063 Escherichia coli ATCC 8739 putative methyltransferase YP_001725034.1 2272269 D 481805 CDS YP_001725035.1 170020081 6067571 2273778..2273957 1 NC_010468.1 KEGG: sbo:SBO_0964 hypothetical protein; hypothetical protein 2273957 6067571 EcolC_2068 Escherichia coli ATCC 8739 hypothetical protein YP_001725035.1 2273778 D 481805 CDS YP_001725036.1 170020082 6067550 2274292..2275605 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: kpn:KPN_pKPN3p05906 Sea24; integrase catalytic subunit 2275605 6067550 EcolC_2069 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001725036.1 2274292 D 481805 CDS YP_001725037.1 170020083 6067545 complement(2276067..2276399) 1 NC_010468.1 KEGG: ent:Ent638_2935 hypothetical protein; hypothetical protein 2276399 6067545 EcolC_2070 Escherichia coli ATCC 8739 hypothetical protein YP_001725037.1 2276067 R 481805 CDS YP_001725038.1 170020084 6067541 2276932..2277171 1 NC_010468.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 2277171 6067541 EcolC_2071 Escherichia coli ATCC 8739 bifunctional antitoxin/transcriptional repressor RelB YP_001725038.1 2276932 D 481805 CDS YP_001725039.1 170020085 6067524 2277171..2277458 1 NC_010468.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sfx:S1669 RelE protein; addiction module antitoxin 2277458 6067524 EcolC_2072 Escherichia coli ATCC 8739 addiction module antitoxin YP_001725039.1 2277171 D 481805 CDS YP_001725040.1 170020086 6067498 2277530..2277685 1 NC_010468.1 PFAM: Hok/gef cell toxic protein; KEGG: sdy:SDY_1432 polypeptide destructive to membrane potential; Hok/gef cell toxic protein 2277685 6067498 EcolC_2073 Escherichia coli ATCC 8739 Hok/gef cell toxic protein YP_001725040.1 2277530 D 481805 CDS YP_001725041.1 170020087 6067487 2277902..2278153 1 NC_010468.1 KEGG: sdy:SDY_1433 hypothetical protein; hypothetical protein 2278153 6067487 EcolC_2074 Escherichia coli ATCC 8739 hypothetical protein YP_001725041.1 2277902 D 481805 CDS YP_001725042.1 170020088 6067478 2278220..2278498 1 NC_010468.1 KEGG: sfl:SF2042 hypothetical protein; hypothetical protein 2278498 6067478 EcolC_2075 Escherichia coli ATCC 8739 hypothetical protein YP_001725042.1 2278220 D 481805 CDS YP_001725043.1 170020089 6067458 2278500..2279549 1 NC_010468.1 PFAM: protein of unknown function DUF1277; SMART: HNH nuclease; KEGG: sfl:SF1546 hypothetical bacteriophage protein; hypothetical protein 2279549 6067458 EcolC_2076 Escherichia coli ATCC 8739 hypothetical protein YP_001725043.1 2278500 D 481805 CDS YP_001725044.1 170020090 6067448 2279563..2280315 1 NC_010468.1 PFAM: antitermination protein; KEGG: esa:ESA_01015 hypothetical protein; antitermination protein 2280315 6067448 EcolC_2077 Escherichia coli ATCC 8739 antitermination protein YP_001725044.1 2279563 D 481805 CDS YP_001725045.1 170020091 6067427 complement(2280737..2280937) 1 NC_010468.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: spt:SPA1603 putative cold shock protein; cold-shock DNA-binding domain-containing protein 2280937 6067427 EcolC_2078 Escherichia coli ATCC 8739 cold-shock DNA-binding domain-containing protein YP_001725045.1 2280737 R 481805 CDS YP_001725046.1 170020092 6067417 2281250..2281465 1 NC_010468.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ent:Ent638_0166 putative cold-shock DNA-binding domain protein; cold-shock DNA-binding domain-containing protein 2281465 6067417 EcolC_2079 Escherichia coli ATCC 8739 cold-shock DNA-binding domain-containing protein YP_001725046.1 2281250 D 481805 CDS YP_001725047.1 170020093 6067397 2281714..2281845 1 NC_010468.1 hypothetical protein 2281845 6067397 EcolC_2080 Escherichia coli ATCC 8739 hypothetical protein YP_001725047.1 2281714 D 481805 CDS YP_001725048.1 170020094 6067394 2282219..2282434 1 NC_010468.1 PFAM: Lysis S family protein; KEGG: ssn:SSON_2438 hypothetical protein; lysis S family protein 2282434 6067394 EcolC_2081 Escherichia coli ATCC 8739 lysis S family protein YP_001725048.1 2282219 D 481805 CDS YP_001725049.1 170020095 6067392 2282439..2282750 1 NC_010468.1 PFAM: protein of unknown function DUF1327; KEGG: ssn:SSON_1892 hypothetical bacteriophage protein; hypothetical protein 2282750 6067392 EcolC_2082 Escherichia coli ATCC 8739 hypothetical protein YP_001725049.1 2282439 D 481805 CDS YP_001725050.1 170020096 6067386 2282747..2283280 1 NC_010468.1 PFAM: glycoside hydrolase family 24; KEGG: sfx:S0733 putative endolysin R of prophage CP-933V; lysozyme 2283280 6067386 EcolC_2083 Escherichia coli ATCC 8739 lysozyme YP_001725050.1 2282747 D 481805 CDS YP_001725051.1 170020097 6067371 2283292..2283774 1 NC_010468.1 KEGG: stm:STM1869 phage-tail assembly-like protein; phage-tail assembly-like protein 2283774 6067371 EcolC_2084 Escherichia coli ATCC 8739 phage-tail assembly-like protein YP_001725051.1 2283292 D 481805 CDS YP_001725052.1 170020098 6067367 2284137..2284349 1 NC_010468.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: stm:STM1996 putative cold-shock protein; cold-shock DNA-binding domain-containing protein 2284349 6067367 EcolC_2085 Escherichia coli ATCC 8739 cold-shock DNA-binding domain-containing protein YP_001725052.1 2284137 D 481805 CDS YP_001725053.1 170020099 6067363 2284675..2284851 1 NC_010468.1 hypothetical protein 2284851 6067363 EcolC_2086 Escherichia coli ATCC 8739 hypothetical protein YP_001725053.1 2284675 D 481805 CDS YP_001725054.1 170020100 6067348 2285023..2285196 1 NC_010468.1 PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA; GnsAGnsB family protein 2285196 6067348 EcolC_2087 Escherichia coli ATCC 8739 GnsAGnsB family protein YP_001725054.1 2285023 D 481805 CDS YP_001725055.1 170020101 6067340 complement(2285348..2285758) 1 NC_010468.1 PFAM: protein of unknown function DUF1398; KEGG: ssn:SSON_2432 hypothetical protein; hypothetical protein 2285758 6067340 EcolC_2088 Escherichia coli ATCC 8739 hypothetical protein YP_001725055.1 2285348 R 481805 CDS YP_001725056.1 170020102 6067325 complement(2285816..2286049) 1 NC_010468.1 hypothetical protein 2286049 6067325 EcolC_2089 Escherichia coli ATCC 8739 hypothetical protein YP_001725056.1 2285816 R 481805 CDS YP_001725057.1 170020103 6067312 2286438..2286983 1 NC_010468.1 PFAM: DNA packaging Nu1; KEGG: ssn:SSON_2431 bacteriophage DNA packaging protein; DNA packaging Nu1 2286983 6067312 EcolC_2090 Escherichia coli ATCC 8739 DNA packaging Nu1 YP_001725057.1 2286438 D 481805 CDS YP_001725058.1 170020104 6067309 2286958..2288883 1 NC_010468.1 PFAM: terminase GpA; KEGG: ssn:SSON_2430 putative DNA packaging protein of prophage; terminase GpA 2288883 6067309 EcolC_2091 Escherichia coli ATCC 8739 terminase GpA YP_001725058.1 2286958 D 481805 CDS YP_001725059.1 170020105 6067305 2288880..2289086 1 NC_010468.1 PFAM: Head-to-tail joining protein W gpW family protein; KEGG: ssn:SSON_2429 putative head-tail joining protein of prophage; head-to-tail joining protein W 2289086 6067305 EcolC_2092 Escherichia coli ATCC 8739 head-to-tail joining protein W YP_001725059.1 2288880 D 481805 CDS YP_001725060.1 170020106 6067303 2289083..2290684 1 NC_010468.1 TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda; KEGG: ssn:SSON_2428 putative capsid structural protein of prophage; lambda family phage portal protein 2290684 6067303 EcolC_2093 Escherichia coli ATCC 8739 lambda family phage portal protein YP_001725060.1 2289083 D 481805 CDS YP_001725061.1 170020107 6067300 2290665..2291984 1 NC_010468.1 PFAM: peptidase S49; KEGG: ssn:SSON_2427 putative minor capsid protein precursor; peptidase S49 2291984 6067300 EcolC_2094 Escherichia coli ATCC 8739 peptidase S49 YP_001725061.1 2290665 D 481805 CDS YP_001725062.1 170020108 6067287 2291994..2292326 1 NC_010468.1 PFAM: lambda head decoration protein D HDPD; KEGG: ssn:SSON_2426 putative head decoration protein; lambda head decoration protein D HDPD 2292326 6067287 EcolC_2095 Escherichia coli ATCC 8739 lambda head decoration protein D HDPD YP_001725062.1 2291994 D 481805 CDS YP_001725063.1 170020109 6067285 2292382..2293407 1 NC_010468.1 PFAM: major capsid protein E; KEGG: ssn:SSON_2425 putative major capsid protein; major capsid protein E 2293407 6067285 EcolC_2096 Escherichia coli ATCC 8739 major capsid protein E YP_001725063.1 2292382 D 481805 CDS YP_001725064.1 170020110 6067278 2293449..2293844 1 NC_010468.1 KEGG: ssn:SSON_2424 putative DNA-packaging protein; putative DNA-packaging protein 2293844 6067278 EcolC_2097 Escherichia coli ATCC 8739 putative DNA-packaging protein YP_001725064.1 2293449 D 481805 CDS YP_001725065.1 170020111 6067266 2293856..2294209 1 NC_010468.1 PFAM: head-tail attachment protein; KEGG: ssn:SSON_2423 putative head-tail joining protein of prophage; head-tail attachment protein 2294209 6067266 EcolC_2098 Escherichia coli ATCC 8739 head-tail attachment protein YP_001725065.1 2293856 D 481805 CDS YP_001725066.1 170020112 6067257 2294297..2294797 1 NC_010468.1 PFAM: Prophage minor tail Z family protein; KEGG: ssn:SSON_2422 putative tail component of prophage; prophage minor tail Z family protein 2294797 6067257 EcolC_2099 Escherichia coli ATCC 8739 prophage minor tail Z family protein YP_001725066.1 2294297 D 481805 CDS YP_001725067.1 170020113 6067253 2294794..2295189 1 NC_010468.1 PFAM: minor tail U; KEGG: ssn:SSON_2421 putative tail component of prophage; minor tail family protein 2295189 6067253 EcolC_2100 Escherichia coli ATCC 8739 minor tail family protein YP_001725067.1 2294794 D 481805 CDS YP_001725068.1 170020114 6067247 2295197..2295937 1 NC_010468.1 PFAM: Ig domain protein group 2 domain protein; KEGG: ssn:SSON_2420 putative tail component of prophage; Ig domain-containing protein 2295937 6067247 EcolC_2101 Escherichia coli ATCC 8739 Ig domain-containing protein YP_001725068.1 2295197 D 481805 CDS YP_001725069.1 170020115 6067243 2295953..2296375 1 NC_010468.1 TIGRFAM: phage minor tail protein G; PFAM: minor tail protein G; KEGG: ssn:SSON_2419 putative tail component of prophage; phage minor tail protein G 2296375 6067243 EcolC_2102 Escherichia coli ATCC 8739 phage minor tail protein G YP_001725069.1 2295953 D 481805 CDS YP_001725070.1 170020116 6067241 2296357..2296791 1 NC_010468.1 TIGRFAM: phage tail assembly protein T; PFAM: Minor tail T family protein; KEGG: ssn:SSON_2418 putative tail component of prophage; phage tail assembly protein T 2296791 6067241 EcolC_2103 Escherichia coli ATCC 8739 phage tail assembly protein T YP_001725070.1 2296357 D 481805 CDS YP_001725071.1 170020117 6067235 2296784..2299345 1 NC_010468.1 TIGRFAM: phage tail tape measure protein, lambda family; PFAM: Prophage tail length tape measure; KEGG: ssn:SSON_2417 putative tail length tape measure protein; lambda family phage tail tape measure protein 2299345 6067235 EcolC_2104 Escherichia coli ATCC 8739 lambda family phage tail tape measure protein YP_001725071.1 2296784 D 481805 CDS YP_001725072.1 170020118 6067226 2299342..2299671 1 NC_010468.1 PFAM: minor tail family protein; KEGG: ssn:SSON_2416 putative minor tail protein; minor tail family protein 2299671 6067226 EcolC_2105 Escherichia coli ATCC 8739 minor tail family protein YP_001725072.1 2299342 D 481805 CDS YP_001725073.1 170020119 6067224 2299671..2300369 1 NC_010468.1 TIGRFAM: phage minor tail protein L; PFAM: minor tail protein L; KEGG: ssn:SSON_2415 putative minor tail protein; phage minor tail protein L 2300369 6067224 EcolC_2106 Escherichia coli ATCC 8739 phage minor tail protein L YP_001725073.1 2299671 D 481805 CDS YP_001725074.1 170020120 6067219 2300375..2301118 1 NC_010468.1 PFAM: NLP/P60 protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ssn:SSON_2414 tail assembly protein; NLP/P60 protein 2301118 6067219 EcolC_2107 Escherichia coli ATCC 8739 NLP/P60 protein YP_001725074.1 2300375 D 481805 CDS YP_001725075.1 170020121 6067206 2301115..2301687 1 NC_010468.1 PFAM: lambda tail assembly I; KEGG: ssn:SSON_2413 putative tail component of prophage; lambda tail assembly I 2301687 6067206 EcolC_2108 Escherichia coli ATCC 8739 lambda tail assembly I YP_001725075.1 2301115 D 481805 CDS YP_001725076.1 170020122 6067203 2301748..2305227 1 NC_010468.1 PFAM: Fibronectin type III domain protein; Protein of unknown function DUF1983; KEGG: ssn:SSON_1763 host specificity protein; hypothetical protein 2305227 6067203 EcolC_2109 Escherichia coli ATCC 8739 hypothetical protein YP_001725076.1 2301748 D 481805 CDS YP_001725077.1 170020123 6067172 2305295..2305894 1 NC_010468.1 PFAM: virulence-related outer membrane protein; KEGG: sbo:SBO_1197 putative membrane protein precursor; virulence-related outer membrane protein 2305894 6067172 EcolC_2110 Escherichia coli ATCC 8739 virulence-related outer membrane protein YP_001725077.1 2305295 D 481805 CDS YP_001725078.1 170020124 6067136 2305959..2308982 1 NC_010468.1 PFAM: tail fiber repeat containing protein; tail fiber repeat 2 protein; Tail Collar domain protein; Prophage tail fibre domain protein; KEGG: ssn:SSON_2410 phage protein-related; prophage tail fiber domain-containing protein 2308982 6067136 EcolC_2111 Escherichia coli ATCC 8739 prophage tail fiber domain-containing protein YP_001725078.1 2305959 D 481805 CDS YP_001725079.1 170020125 6067134 2308982..2309557 1 NC_010468.1 PFAM: tail assembly chaperone gp38; KEGG: stm:STM1050 tail fiber assembly like-protein; tail assembly chaperone gp38 2309557 6067134 EcolC_2112 Escherichia coli ATCC 8739 tail assembly chaperone gp38 YP_001725079.1 2308982 D 481805 CDS YP_001725080.1 170020126 6067121 complement(2309655..2310245) 1 NC_010468.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: sbl:Sbal_4419 resolvase, N-terminal domain; resolvase domain-containing protein 2310245 6067121 EcolC_2113 Escherichia coli ATCC 8739 resolvase domain-containing protein YP_001725080.1 2309655 R 481805 CDS YP_001725081.1 170020127 6067109 complement(2310562..2310795) 1 NC_010468.1 KEGG: ent:Ent638_2496 DNA-binding transcriptional regulator; DNA-binding transcriptional regulator 2310795 6067109 EcolC_2114 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator YP_001725081.1 2310562 R 481805 CDS YP_001725082.1 170020128 6067107 2311582..2312865 1 NC_010468.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_1582 putative transport protein; major facilitator superfamily metabolite/H(+) symporter 2312865 6067107 EcolC_2115 Escherichia coli ATCC 8739 major facilitator superfamily metabolite/H(+) symporter YP_001725082.1 2311582 D 481805 CDS YP_001725083.1 170020129 6067095 2312954..2314414 1 NC_010468.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfx:S1678 putative oxidoreductase; mannitol dehydrogenase domain-containing protein 2314414 6067095 EcolC_2116 Escherichia coli ATCC 8739 mannitol dehydrogenase domain-containing protein YP_001725083.1 2312954 D 481805 CDS YP_001725084.1 170020130 6067073 complement(2314450..2314653) 1 NC_010468.1 KEGG: sdy:SDY_1584 hypothetical protein; hypothetical protein 2314653 6067073 EcolC_2117 Escherichia coli ATCC 8739 hypothetical protein YP_001725084.1 2314450 R 481805 CDS YP_001725085.1 170020131 6067070 complement(2314830..2315516) 1 NC_010468.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ssn:SSON_1588 hypothetical protein; GntR family transcriptional regulator 2315516 6067070 EcolC_2118 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001725085.1 2314830 R 481805 CDS YP_001725086.1 170020132 6067049 complement(2315605..2316351) 1 NC_010468.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 2316351 6067049 EcolC_2119 Escherichia coli ATCC 8739 3-hydroxy acid dehydrogenase YP_001725086.1 2315605 R 481805 CDS YP_001725087.1 170020133 6066996 2316488..2318533 1 NC_010468.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: ssn:SSON_1590 dipeptidyl carboxypeptidase II; dipeptidyl carboxypeptidase II 2318533 6066996 EcolC_2120 Escherichia coli ATCC 8739 dipeptidyl carboxypeptidase II YP_001725087.1 2316488 D 481805 CDS YP_001725088.1 170020134 6066966 complement(2318578..2319096) 1 NC_010468.1 PFAM: CinA domain protein; KEGG: sdy:SDY_1588 hypothetical protein; competence damage-inducible protein A 2319096 6066966 EcolC_2121 Escherichia coli ATCC 8739 competence damage-inducible protein A YP_001725088.1 2318578 R 481805 CDS YP_001725089.1 170020135 6066932 2319372..2319764 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_1592 hypothetical protein; hypothetical protein 2319764 6066932 EcolC_2122 Escherichia coli ATCC 8739 hypothetical protein YP_001725089.1 2319372 D 481805 CDS YP_001725090.1 170020136 6066901 2320019..2320909 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1593 hypothetical protein; hypothetical protein 2320909 6066901 EcolC_2123 Escherichia coli ATCC 8739 hypothetical protein YP_001725090.1 2320019 D 481805 CDS YP_001725091.1 170020137 6066848 complement(2321350..2322537) 1 NC_010468.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 2322537 6066848 EcolC_2124 Escherichia coli ATCC 8739 putative MFS-type transporter YdeE YP_001725091.1 2321350 R 481805 CDS YP_001725092.1 170020138 6065935 2322732..2323631 1 NC_010468.1 PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: sfv:SFV_1593 hypothetical protein; O-acetylserine/cysteine export protein 2323631 6065935 EcolC_2125 Escherichia coli ATCC 8739 O-acetylserine/cysteine export protein YP_001725092.1 2322732 D 481805 CDS YP_001725093.1 170020139 6065777 complement(2323662..2323880) 1 NC_010468.1 KEGG: sbo:SBO_1650 multiple antibiotic resistance protein; hypothetical protein 2323880 6065777 EcolC_2126 Escherichia coli ATCC 8739 hypothetical protein YP_001725093.1 2323662 R 481805 CDS YP_001725094.1 170020140 6065738 complement(2323912..2324295) 1 NC_010468.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 2324295 6065738 EcolC_2127 Escherichia coli ATCC 8739 DNA-binding transcriptional activator MarA YP_001725094.1 2323912 R 481805 CDS YP_001725095.1 170020141 6065668 complement(2324315..2324749) 1 NC_010468.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 2324749 6065668 EcolC_2128 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor MarR YP_001725095.1 2324315 R 481805 CDS YP_001725096.1 170020142 6065465 2324960..2325625 1 NC_010468.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 2325625 6065465 EcolC_2129 Escherichia coli ATCC 8739 multiple drug resistance protein MarC YP_001725096.1 2324960 D 481805 CDS YP_001725097.1 170020143 6065410 complement(2325650..2326840) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1646 putative resistance/regulatory protein; sugar efflux transporter 2326840 6065410 EcolC_2130 Escherichia coli ATCC 8739 sugar efflux transporter YP_001725097.1 2325650 R 481805 CDS YP_001725098.1 170020144 6065386 complement(2326990..2328105) 1 NC_010468.1 KEGG: sfx:S1694 hypothetical protein; hypothetical protein 2328105 6065386 EcolC_2131 Escherichia coli ATCC 8739 hypothetical protein YP_001725098.1 2326990 R 481805 CDS YP_001725099.1 170020145 6065314 complement(2328183..2329064) 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sdy:SDY_1633 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2329064 6065314 EcolC_2132 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725099.1 2328183 R 481805 CDS YP_001725100.1 170020146 6065295 2329165..2330553 1 NC_010468.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate-semialdehyde dehydrogenase 2330553 6065295 EcolC_2133 Escherichia coli ATCC 8739 putative succinate-semialdehyde dehydrogenase YP_001725100.1 2329165 D 481805 CDS YP_001725101.1 170020147 6065265 2330617..2331543 1 NC_010468.1 catalyzes the formation of glutamate from glutamine; glutaminase 2331543 6065265 EcolC_2134 Escherichia coli ATCC 8739 glutaminase YP_001725101.1 2330617 D 481805 CDS YP_001725102.1 170020148 6066342 2331543..2331902 1 NC_010468.1 KEGG: sbo:SBO_1641 hypothetical protein; hypothetical protein 2331902 6066342 EcolC_2135 Escherichia coli ATCC 8739 hypothetical protein YP_001725102.1 2331543 D 481805 CDS YP_001725103.1 170020149 6064781 2332014..2332961 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbo:SBO_1640 hypothetical protein; diguanylate cyclase 2332961 6064781 EcolC_2136 Escherichia coli ATCC 8739 diguanylate cyclase YP_001725103.1 2332014 D 481805 CDS YP_001725104.1 170020150 6067400 2333187..2334638 1 NC_010468.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 2334638 6067400 EcolC_2137 Escherichia coli ATCC 8739 altronate oxidoreductase YP_001725104.1 2333187 D 481805 CDS YP_001725105.1 170020151 6065792 2334845..2335759 1 NC_010468.1 PFAM: protein of unknown function UPF0187; KEGG: sfv:SFV_1577 hypothetical protein; hypothetical protein 2335759 6065792 EcolC_2138 Escherichia coli ATCC 8739 hypothetical protein YP_001725105.1 2334845 D 481805 CDS YP_001725106.1 170020152 6066998 complement(2335763..2336521) 1 NC_010468.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 2336521 6066998 EcolC_2139 Escherichia coli ATCC 8739 trans-aconitate 2-methyltransferase YP_001725106.1 2335763 R 481805 CDS YP_001725107.1 170020153 6064446 complement(2336578..2336868) 1 NC_010468.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sdy:SDY_1624 hypothetical protein; autoinducer-2 (AI-2) modifying protein LsrG 2336868 6064446 EcolC_2140 Escherichia coli ATCC 8739 autoinducer-2 (AI-2) modifying protein LsrG YP_001725107.1 2336578 R 481805 CDS YP_001725108.1 170020154 6065320 complement(2336892..2337767) 1 NC_010468.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: stm:STM4078 putative fructose-1,6-bisphosphate aldolase; aldolase 2337767 6065320 EcolC_2141 Escherichia coli ATCC 8739 aldolase YP_001725108.1 2336892 R 481805 CDS YP_001725109.1 170020155 6066233 complement(2337794..2338816) 1 NC_010468.1 KEGG: stm:STM4077 putative ABC superfamily (peri_perm), sugar transport protein; sugar ABC transporter periplasmic subunit 2338816 6066233 EcolC_2142 Escherichia coli ATCC 8739 sugar ABC transporter periplasmic subunit YP_001725109.1 2337794 R 481805 CDS YP_001725110.1 170020156 6064726 complement(2338828..2339820) 1 NC_010468.1 PFAM: inner-membrane translocator; KEGG: sfv:SFV_1570 putative transport system permease protein; monosaccharide-transporting ATPase 2339820 6064726 EcolC_2143 Escherichia coli ATCC 8739 monosaccharide-transporting ATPase YP_001725110.1 2338828 R 481805 CDS YP_001725111.1 170020157 6067128 complement(2339820..2340848) 1 NC_010468.1 PFAM: inner-membrane translocator; KEGG: sfv:SFV_1569 putative transport system permease protein; monosaccharide-transporting ATPase 2340848 6067128 EcolC_2144 Escherichia coli ATCC 8739 monosaccharide-transporting ATPase YP_001725111.1 2339820 R 481805 CDS YP_001725112.1 170020158 6066507 complement(2340842..2342377) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_1568 putative ATP-binding component of a transport system; ABC transporter-like protein 2342377 6066507 EcolC_2145 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725112.1 2340842 R 481805 CDS YP_001725113.1 170020159 6064890 2342626..2343579 1 NC_010468.1 PFAM: putative sugar-binding domain protein; KEGG: sfv:SFV_1567 putative transcriptional regulator; DeoR family transcriptional regulator 2343579 6064890 EcolC_2146 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001725113.1 2342626 D 481805 CDS YP_001725114.1 170020160 6066311 2343658..2345250 1 NC_010468.1 PFAM: carbohydrate kinase FGGY; KEGG: stt:t3546 putative sugar kinase; autoinducer-2 (AI-2) kinase 2345250 6066311 EcolC_2147 Escherichia coli ATCC 8739 autoinducer-2 (AI-2) kinase YP_001725114.1 2343658 D 481805 CDS YP_001725115.1 170020161 6066806 2345781..2351201 1 NC_010468.1 TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ssn:SSON_1611 hypothetical protein; putative lipoprotein/autotransporter domain-containing protein 2351201 6066806 EcolC_2148 Escherichia coli ATCC 8739 putative lipoprotein/autotransporter domain-containing protein YP_001725115.1 2345781 D 481805 CDS YP_001725116.1 170020162 6065560 2351424..2351690 1 NC_010468.1 PFAM: helix-turn-helix domain protein; KEGG: ssn:SSON_1613 persistence to inhibition of murein or DNA biosynthesis; DNA-binding transcriptional regulator HipB 2351690 6065560 EcolC_2149 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator HipB YP_001725116.1 2351424 D 481805 CDS YP_001725117.1 170020163 6066434 2351690..2353012 1 NC_010468.1 TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: kpn:KPN_01668 persistence to inhibition of murein or DNA biosynthesis, DNA-binding regulator; HipA domain-containing protein 2353012 6066434 EcolC_2150 Escherichia coli ATCC 8739 HipA domain-containing protein YP_001725117.1 2351690 D 481805 CDS YP_001725118.1 170020164 6065540 2353865..2355013 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: cko:CKO_03711 hypothetical protein; fimbrial biogenesis outer membrane usher protein 2355013 6065540 EcolC_2152 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001725118.1 2353865 D 481805 CDS YP_001725119.1 170020165 6064989 2355027..2355557 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: cko:CKO_03712 hypothetical protein; fimbrial protein 2355557 6064989 EcolC_2153 Escherichia coli ATCC 8739 fimbrial protein YP_001725119.1 2355027 D 481805 CDS YP_001725120.1 170020166 6065065 2355570..2356073 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: sbo:SBO_4369 fimbrial morphology; fimbrial protein 2356073 6065065 EcolC_2154 Escherichia coli ATCC 8739 fimbrial protein YP_001725120.1 2355570 D 481805 CDS YP_001725121.1 170020167 6064865 2356132..2357046 1 NC_010468.1 PFAM: Fimbrial protein ; FimH mannose-binding domain protein; KEGG: ssn:SSON_1621 putative adhesin; FimH mannose-binding domain-containing protein 2357046 6064865 EcolC_2155 Escherichia coli ATCC 8739 FimH mannose-binding domain-containing protein YP_001725121.1 2356132 D 481805 CDS YP_001725122.1 170020168 6065505 2357380..2359659 1 NC_010468.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase 2359659 6065505 EcolC_2156 Escherichia coli ATCC 8739 putative oxidoreductase YP_001725122.1 2357380 D 481805 CDS YP_001725123.1 170020169 6065599 2359907..2360104 1 NC_010468.1 KEGG: sfx:S1655 hypothetical protein; hypothetical protein 2360104 6065599 EcolC_2157 Escherichia coli ATCC 8739 hypothetical protein YP_001725123.1 2359907 D 481805 CDS YP_001725124.1 170020170 6066249 2360179..2360940 1 NC_010468.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 2360940 6066249 EcolC_2158 Escherichia coli ATCC 8739 transcriptional regulator YdeO YP_001725124.1 2360179 D 481805 CDS YP_001725125.1 170020171 6065362 2361342..2363024 1 NC_010468.1 PFAM: sulfatase; KEGG: sbo:SBO_1558 putative sulfatase; sulfatase 2363024 6065362 EcolC_2159 Escherichia coli ATCC 8739 sulfatase YP_001725125.1 2361342 D 481805 CDS YP_001725126.1 170020172 6065509 2363076..2364233 1 NC_010468.1 PFAM: Radical SAM domain protein; KEGG: sfv:SFV_1723 putative enzyme; radical SAM domain-containing protein 2364233 6065509 EcolC_2160 Escherichia coli ATCC 8739 radical SAM domain-containing protein YP_001725126.1 2363076 D 481805 CDS YP_001725127.1 170020173 6066072 2364524..2366209 1 NC_010468.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_1627 putative ATP-binding component of a transport system; ABC transporter-like protein 2366209 6066072 EcolC_2161 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725127.1 2364524 D 481805 CDS YP_001725128.1 170020174 6067001 2366247..2368619 1 NC_010468.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1629 hypothetical protein; TonB-dependent receptor plug 2368619 6067001 EcolC_2162 Escherichia coli ATCC 8739 TonB-dependent receptor plug YP_001725128.1 2366247 D 481805 CDS YP_001725129.1 170020175 6066999 2368676..2371459 1 NC_010468.1 PFAM: peptidase M16 domain protein; KEGG: sbo:SBO_1562 putative peptidase; peptidase M16 domain-containing protein 2371459 6066999 EcolC_2163 Escherichia coli ATCC 8739 peptidase M16 domain-containing protein YP_001725129.1 2368676 D 481805 CDS YP_001725130.1 170020176 6065829 2371821..2373221 1 NC_010468.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_1563 glutamate decarboxylase isozyme; glutamate decarboxylase 2373221 6065829 EcolC_2164 Escherichia coli ATCC 8739 glutamate decarboxylase YP_001725130.1 2371821 D 481805 CDS YP_001725131.1 170020177 6066051 2373377..2374912 1 NC_010468.1 TIGRFAM: glutamate/g-aminobutyrate antiporter; PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1564 acid sensitivity protein, putative transporter; glutamate/g-aminobutyrate antiporter 2374912 6066051 EcolC_2165 Escherichia coli ATCC 8739 glutamate/g-aminobutyrate antiporter YP_001725131.1 2373377 D 481805 CDS YP_001725132.1 170020178 6064948 2375208..2376362 1 NC_010468.1 PFAM: protein of unknown function DUF187; KEGG: ssn:SSON_1633 hypothetical protein; hypothetical protein 2376362 6064948 EcolC_2166 Escherichia coli ATCC 8739 hypothetical protein YP_001725132.1 2375208 D 481805 CDS YP_001725133.1 170020179 6067236 2376734..2378116 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1634 hypothetical protein; diguanylate cyclase 2378116 6067236 EcolC_2167 Escherichia coli ATCC 8739 diguanylate cyclase YP_001725133.1 2376734 D 481805 CDS YP_001725134.1 170020180 6067485 2378141..2380540 1 NC_010468.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 2380540 6067485 EcolC_2168 Escherichia coli ATCC 8739 cAMP phosphodiesterase YP_001725134.1 2378141 D 481805 CDS YP_001725135.1 170020181 6066629 2380798..2381379 1 NC_010468.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 2381379 6066629 EcolC_2169 Escherichia coli ATCC 8739 D-alanyl-D-alanine dipeptidase YP_001725135.1 2380798 D 481805 CDS YP_001725136.1 170020182 6067665 2381393..2382943 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1637 putative hemin-binding lipoprotein; extracellular solute-binding protein 2382943 6067665 EcolC_2170 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725136.1 2381393 D 481805 CDS YP_001725137.1 170020183 6066166 2382945..2383967 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1571 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 2383967 6066166 EcolC_2171 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725137.1 2382945 D 481805 CDS YP_001725138.1 170020184 6065077 2383964..2384860 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1639 putative transport protein; ATP-dependent peptide transporter membrane subunit 2384860 6065077 EcolC_2172 Escherichia coli ATCC 8739 ATP-dependent peptide transporter membrane subunit YP_001725138.1 2383964 D 481805 CDS YP_001725139.1 170020185 6066381 2384857..2385843 1 NC_010468.1 KEGG: sbo:SBO_1573 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2385843 6066381 EcolC_2173 Escherichia coli ATCC 8739 oligopeptide/dipeptide ABC transporter ATPase YP_001725139.1 2384857 D 481805 CDS YP_001725140.1 170020186 6065491 2385836..2386762 1 NC_010468.1 KEGG: sbo:SBO_1574 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2386762 6065491 EcolC_2174 Escherichia coli ATCC 8739 oligopeptide/dipeptide ABC transporter ATPase YP_001725140.1 2385836 D 481805 CDS YP_001725141.1 170020187 6065102 complement(2386818..2387249) 1 NC_010468.1 PFAM: OsmC family protein; KEGG: sfv:SFV_1739 osmotically inducible protein; OsmC family protein 2387249 6065102 EcolC_2175 Escherichia coli ATCC 8739 OsmC family protein YP_001725141.1 2386818 R 481805 CDS YP_001725142.1 170020188 6067469 2387594..2387809 1 NC_010468.1 KEGG: sbo:SBO_1576 hypothetical protein; biofilm-dependent modulation protein 2387809 6067469 EcolC_2176 Escherichia coli ATCC 8739 biofilm-dependent modulation protein YP_001725142.1 2387594 D 481805 CDS YP_001725143.1 170020189 6065133 2387911..2388048 1 NC_010468.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 2388048 rpsV 6065133 rpsV Escherichia coli ATCC 8739 30S ribosomal subunit S22 YP_001725143.1 2387911 D 481805 CDS YP_001725144.1 170020190 6067594 2388205..2389902 1 NC_010468.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 2389902 6067594 EcolC_2178 Escherichia coli ATCC 8739 malate dehydrogenase YP_001725144.1 2388205 D 481805 CDS YP_001725145.1 170020191 6065375 2390036..2391046 1 NC_010468.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 2391046 6065375 EcolC_2179 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001725145.1 2390036 D 481805 CDS YP_001725146.1 170020192 6066457 2391192..2391476 1 NC_010468.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sbo:SBO_1580 hypothetical protein; XRE family plasmid maintenance system antidote protein 2391476 6066457 EcolC_2180 Escherichia coli ATCC 8739 XRE family plasmid maintenance system antidote protein YP_001725146.1 2391192 D 481805 CDS YP_001725147.1 170020193 6066658 complement(2391705..2392358) 1 NC_010468.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 2392358 6066658 EcolC_2181 Escherichia coli ATCC 8739 formate dehydrogenase-N subunit gamma YP_001725147.1 2391705 R 481805 CDS YP_001725148.1 170020194 6065050 complement(2392351..2393235) 1 NC_010468.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbo:SBO_1582 formate dehydrogenase N, nitrate-inducible, iron-sulfur beta subunit; formate dehydrogenase subunit beta 2393235 6065050 EcolC_2182 Escherichia coli ATCC 8739 formate dehydrogenase subunit beta YP_001725148.1 2392351 R 481805 CDS YP_001725149.1 170020195 6067466 complement(2393248..2396295) 1 NC_010468.1 KEGG: ssn:SSON_1650 formate dehydrogenase-N, nitrate-inducible, alpha subunit; Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; formate dehydrogenase subunit alpha 2396295 6067466 EcolC_2183 Escherichia coli ATCC 8739 formate dehydrogenase subunit alpha YP_001725149.1 2393248 R 481805 CDS YP_001725150.1 170020196 6065629 2396584..2397408 1 NC_010468.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_1651 hypothetical protein; hypothetical protein 2397408 6065629 EcolC_2184 Escherichia coli ATCC 8739 hypothetical protein YP_001725150.1 2396584 D 481805 CDS YP_001725151.1 170020197 6064772 2397667..2397957 1 NC_010468.1 KEGG: sbo:SBO_1585 putative outer membrane porin protein; putative outer membrane porin protein 2397957 6064772 EcolC_2185 Escherichia coli ATCC 8739 putative outer membrane porin protein YP_001725151.1 2397667 D 481805 CDS YP_001725152.1 170020198 6066536 2398017..2399312 1 NC_010468.1 KEGG: sfv:SFV_1753 putative glycoportein; hypothetical protein 2399312 6066536 EcolC_2186 Escherichia coli ATCC 8739 hypothetical protein YP_001725152.1 2398017 D 481805 CDS YP_001725153.1 170020199 6066539 2399636..2401024 1 NC_010468.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_1756 nitrite extrusion protein 2; nitrite transporter 2401024 6066539 EcolC_2187 Escherichia coli ATCC 8739 nitrite transporter YP_001725153.1 2399636 D 481805 CDS YP_001725154.1 170020200 6066028 2401106..2404846 1 NC_010468.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1757 cryptic nitrate reductase 2, alpha subunit; nitrate reductase subunit alpha 2404846 6066028 EcolC_2188 Escherichia coli ATCC 8739 nitrate reductase subunit alpha YP_001725154.1 2401106 D 481805 CDS YP_001725155.1 170020201 6066070 2404843..2406387 1 NC_010468.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: ssn:SSON_1658 cryptic nitrate reductase 2, beta subunit; nitrate reductase subunit beta 2406387 6066070 EcolC_2189 Escherichia coli ATCC 8739 nitrate reductase subunit beta YP_001725155.1 2404843 D 481805 CDS YP_001725156.1 170020202 6066332 2406387..2407082 1 NC_010468.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: ssn:SSON_1659 cryptic nitrate reductase 2, delta subunit, assembly function; nitrate reductase molybdenum cofactor assembly chaperone 2407082 6066332 EcolC_2190 Escherichia coli ATCC 8739 nitrate reductase molybdenum cofactor assembly chaperone YP_001725156.1 2406387 D 481805 CDS YP_001725157.1 170020203 6066461 2407079..2407759 1 NC_010468.1 KEGG: sdy:SDY_1653 cryptic nitrate reductase 2, gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit; respiratory nitrate reductase subunit gamma 2407759 6066461 EcolC_2191 Escherichia coli ATCC 8739 respiratory nitrate reductase subunit gamma YP_001725157.1 2407079 D 481805 CDS YP_001725158.1 170020204 6066977 2407838..2408731 1 NC_010468.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sdy:SDY_1654 hypothetical protein; hypothetical protein 2408731 6066977 EcolC_2192 Escherichia coli ATCC 8739 hypothetical protein YP_001725158.1 2407838 D 481805 CDS YP_001725159.1 170020205 6066160 complement(2408827..2409672) 1 NC_010468.1 PFAM: N-acetyltransferase; KEGG: ssn:SSON_1662 putative N-hydroxyarylamine O-acetyltransferase; N-hydroxyarylamine O-acetyltransferase 2409672 6066160 EcolC_2193 Escherichia coli ATCC 8739 N-hydroxyarylamine O-acetyltransferase YP_001725159.1 2408827 R 481805 CDS YP_001725160.1 170020206 6066046 2409845..2410414 1 NC_010468.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: ssn:SSON_1663 hypothetical protein; flavin reductase domain-containing protein 2410414 6066046 EcolC_2194 Escherichia coli ATCC 8739 flavin reductase domain-containing protein YP_001725160.1 2409845 D 481805 CDS YP_001725161.1 170020207 6065514 complement(2410418..2410645) 1 NC_010468.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 2410645 6065514 EcolC_2195 Escherichia coli ATCC 8739 4-oxalocrotonate tautomerase YP_001725161.1 2410418 R 481805 CDS YP_001725162.1 170020208 6065512 complement(2410678..2411469) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein 2411469 6065512 EcolC_2196 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001725162.1 2410678 R 481805 CDS YP_001725163.1 170020209 6064974 complement(2411676..2412998) 1 NC_010468.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: lpc:LPC_1850 reverse transcriptase; RNA-directed DNA polymerase 2412998 6064974 EcolC_2197 Escherichia coli ATCC 8739 RNA-directed DNA polymerase YP_001725163.1 2411676 R 481805 CDS YP_001725164.1 170020210 6065033 complement(2413524..2413898) 1 NC_010468.1 hypothetical protein 2413898 6065033 EcolC_2198 Escherichia coli ATCC 8739 hypothetical protein YP_001725164.1 2413524 R 481805 CDS YP_001725165.1 170020211 6065446 join(2415395..2415649,2415649..2416092) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 2416092 6065446 EcolC_2200 Escherichia coli ATCC 8739 insertion element protein YP_001725165.1 2415395 D 481805 CDS YP_001725166.1 170020212 6064804 complement(2416103..2419909) 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 2419909 6064804 EcolC_2201 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001725166.1 2416103 R 481805 CDS YP_001725167.1 170020213 6064823 complement(2419976..2422084) 1 NC_010468.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ssn:SSON_1677 unknown protein associated with rhs element; ImpA family type VI secretion-associated protein 2422084 6064823 EcolC_2202 Escherichia coli ATCC 8739 ImpA family type VI secretion-associated protein YP_001725167.1 2419976 R 481805 CDS YP_001725168.1 170020214 6064820 complement(2422154..2423290) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein 2423290 6064820 EcolC_2203 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001725168.1 2422154 R 481805 CDS YP_001725169.1 170020215 6064850 complement(2424206..2424406) 1 NC_010468.1 KEGG: ssn:SSON_1678 hypothetical protein; hypothetical protein 2424406 6064850 EcolC_2204 Escherichia coli ATCC 8739 hypothetical protein YP_001725169.1 2424206 R 481805 CDS YP_001725170.1 170020216 6066578 complement(2424494..2425093) 1 NC_010468.1 KEGG: sbo:SBO_1593 putative transferase; putative transferase 2425093 6066578 EcolC_2205 Escherichia coli ATCC 8739 putative transferase YP_001725170.1 2424494 R 481805 CDS YP_001725171.1 170020217 6065679 2425359..2426858 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1594 L-asparagine permease; amino acid permease-associated protein 2426858 6065679 EcolC_2206 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001725171.1 2425359 D 481805 CDS YP_001725172.1 170020218 6065879 complement(2426973..2428034) 1 NC_010468.1 KEGG: sbo:SBO_1595 putative receptor; putative receptor 2428034 6065879 EcolC_2207 Escherichia coli ATCC 8739 putative receptor YP_001725172.1 2426973 R 481805 CDS YP_001725173.1 170020219 6067101 2428276..2430378 1 NC_010468.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1682 putative outer membrane receptor for iron transport; TonB-dependent receptor 2430378 6067101 EcolC_2208 Escherichia coli ATCC 8739 TonB-dependent receptor YP_001725173.1 2428276 D 481805 CDS YP_001725174.1 170020220 6065537 complement(2430414..2431079) 1 NC_010468.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfv:SFV_1761 hypothetical protein; putative DNA-binding transcriptional regulator 2431079 6065537 EcolC_2209 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001725174.1 2430414 R 481805 CDS YP_001725175.1 170020221 6065464 complement(2431277..2432314) 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1762 putative oxidoreductase; alcohol dehydrogenase 2432314 6065464 EcolC_2210 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001725175.1 2431277 R 481805 CDS YP_001725176.1 170020222 6066866 2432495..2433013 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_1688 putative resistance protein; N-acetyltransferase GCN5 2433013 6066866 EcolC_2211 Escherichia coli ATCC 8739 N-acetyltransferase GCN5 YP_001725176.1 2432495 D 481805 CDS YP_001725177.1 170020223 6064447 2433010..2433459 1 NC_010468.1 PFAM: protein of unknown function DUF606; KEGG: sbo:SBO_1601 hypothetical protein; hypothetical protein 2433459 6064447 EcolC_2212 Escherichia coli ATCC 8739 hypothetical protein YP_001725177.1 2433010 D 481805 CDS YP_001725178.1 170020224 6066291 complement(2433460..2433693) 1 NC_010468.1 KEGG: sbo:SBO_1602 hypothetical protein; hypothetical protein 2433693 6066291 EcolC_2213 Escherichia coli ATCC 8739 hypothetical protein YP_001725178.1 2433460 R 481805 CDS YP_001725179.1 170020225 6064860 complement(2433779..2434000) 1 NC_010468.1 KEGG: sdy:SDY_1729 hypothetical protein; hypothetical protein 2434000 6064860 EcolC_2214 Escherichia coli ATCC 8739 hypothetical protein YP_001725179.1 2433779 R 481805 CDS YP_001725180.1 170020226 6067156 complement(2434339..2435763) 1 NC_010468.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 2435763 6067156 EcolC_2215 Escherichia coli ATCC 8739 gamma-aminobutyraldehyde dehydrogenase YP_001725180.1 2434339 R 481805 CDS YP_001725181.1 170020227 6066400 complement(2435785..2436579) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_1771 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 2436579 6066400 EcolC_2216 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725181.1 2435785 R 481805 CDS YP_001725182.1 170020228 6065455 complement(2436569..2437510) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ent:Ent638_2126 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport system inner membrane protein 2437510 6065455 EcolC_2217 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725182.1 2436569 R 481805 CDS YP_001725183.1 170020229 6065331 complement(2437511..2438524) 1 NC_010468.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_1696 putative ATP-binding component of a transport system; ABC transporter-like protein 2438524 6065331 EcolC_2218 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725183.1 2437511 R 481805 CDS YP_001725184.1 170020230 6064924 complement(2438542..2439687) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1697 putative transport protein; extracellular solute-binding protein 2439687 6064924 EcolC_2219 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725184.1 2438542 R 481805 CDS YP_001725185.1 170020231 6065260 complement(2439932..2441338) 1 NC_010468.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: ssn:SSON_1698 multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system; transcriptional regulator 2441338 6065260 EcolC_2220 Escherichia coli ATCC 8739 transcriptional regulator YP_001725185.1 2439932 R 481805 CDS YP_001725186.1 170020232 6066919 complement(2441417..2441854) 1 NC_010468.1 PFAM: helix-turn-helix domain protein; protein of unknown function UPF0150; KEGG: sdy:SDY_1736 hypothetical protein; XRE family transcriptional regulator 2441854 6066919 EcolC_2221 Escherichia coli ATCC 8739 XRE family transcriptional regulator YP_001725186.1 2441417 R 481805 CDS YP_001725187.1 170020233 6065542 complement(2441879..2442055) 1 NC_010468.1 PFAM: YcfA family protein; KEGG: cko:CKO_01475 hypothetical protein; hypothetical protein 2442055 6065542 EcolC_2222 Escherichia coli ATCC 8739 hypothetical protein YP_001725187.1 2441879 R 481805 CDS YP_001725188.1 170020234 6065696 2442277..2442507 1 NC_010468.1 KEGG: ssn:SSON_1702 hypothetical protein; hypothetical protein 2442507 6065696 EcolC_2223 Escherichia coli ATCC 8739 hypothetical protein YP_001725188.1 2442277 D 481805 CDS YP_001725189.1 170020235 6064980 complement(2442599..2444602) 1 NC_010468.1 PFAM: peptidase U32; KEGG: ssn:SSON_1703 putative collagenase; peptidase U32 2444602 6064980 EcolC_2224 Escherichia coli ATCC 8739 peptidase U32 YP_001725189.1 2442599 R 481805 CDS YP_001725190.1 170020236 6066356 complement(2444633..2445169) 1 NC_010468.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: ssn:SSON_1704 hypothetical protein; XRE family transcriptional regulator 2445169 6066356 EcolC_2225 Escherichia coli ATCC 8739 XRE family transcriptional regulator YP_001725190.1 2444633 R 481805 CDS YP_001725191.1 170020237 6066830 2445261..2446436 1 NC_010468.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: cko:CKO_01471 hypothetical protein; benzoate transporter 2446436 6066830 EcolC_2226 Escherichia coli ATCC 8739 benzoate transporter YP_001725191.1 2445261 D 481805 CDS YP_001725192.1 170020238 6066563 complement(2446476..2447624) 1 NC_010468.1 KEGG: ssn:SSON_1709 putative virulence protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; IS605 family transposase OrfB 2447624 6066563 EcolC_2227 Escherichia coli ATCC 8739 IS605 family transposase OrfB YP_001725192.1 2446476 R 481805 CDS YP_001725193.1 170020239 6066043 complement(2448216..2448884) 1 NC_010468.1 KEGG: sfv:SFV_1775 hypothetical protein; hypothetical protein 2448884 6066043 EcolC_2229 Escherichia coli ATCC 8739 hypothetical protein YP_001725193.1 2448216 R 481805 CDS YP_001725194.1 170020240 6065770 complement(2449187..2449780) 1 NC_010468.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 2449780 6065770 EcolC_2230 Escherichia coli ATCC 8739 tellurite resistance protein TehB YP_001725194.1 2449187 R 481805 CDS YP_001725195.1 170020241 6066500 complement(2449777..2450769) 1 NC_010468.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: sfv:SFV_1777 tellurite resistance; potassium-tellurite ethidium and proflavin transporter 2450769 6066500 EcolC_2231 Escherichia coli ATCC 8739 potassium-tellurite ethidium and proflavin transporter YP_001725195.1 2449777 R 481805 CDS YP_001725196.1 170020242 6066909 2450893..2451873 1 NC_010468.1 KEGG: sfv:SFV_1778 hypothetical protein; hypothetical protein 2451873 6066909 EcolC_2232 Escherichia coli ATCC 8739 hypothetical protein YP_001725196.1 2450893 D 481805 CDS YP_001725197.1 170020243 6067336 complement(2451868..2452404) 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_1660 acetyl transferase; ribosomal-protein-L7/L12-serine acetyltransferase 2452404 6067336 EcolC_2233 Escherichia coli ATCC 8739 ribosomal-protein-L7/L12-serine acetyltransferase YP_001725197.1 2451868 R 481805 CDS YP_001725198.1 170020244 6066348 complement(2452467..2452691) 1 NC_010468.1 PFAM: protein of unknown function DUF465; KEGG: sfv:SFV_1780 hypothetical protein; hypothetical protein 2452691 6066348 EcolC_2234 Escherichia coli ATCC 8739 hypothetical protein YP_001725198.1 2452467 R 481805 CDS YP_001725199.1 170020245 6065912 complement(2452831..2454450) 1 NC_010468.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 2454450 mdoD 6065912 mdoD Escherichia coli ATCC 8739 glucan biosynthesis protein D YP_001725199.1 2452831 R 481805 CDS YP_001725200.1 170020246 6066347 complement(2454711..2456054) 1 NC_010468.1 PFAM: protein of unknown function DUF1338; KEGG: sdy:SDY_1757 hypothetical protein; hypothetical protein 2456054 6066347 EcolC_2236 Escherichia coli ATCC 8739 hypothetical protein YP_001725200.1 2454711 R 481805 CDS YP_001725201.1 170020247 6067319 2456175..2457194 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1720 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2457194 6067319 EcolC_2237 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725201.1 2456175 D 481805 CDS YP_001725202.1 170020248 6067316 complement(2457232..2458872) 1 NC_010468.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ssn:SSON_1721 methyl-accepting chemotaxis protein III; methyl-accepting chemotaxis sensory transducer 2458872 6067316 EcolC_2238 Escherichia coli ATCC 8739 methyl-accepting chemotaxis sensory transducer YP_001725202.1 2457232 R 481805 CDS YP_001725203.1 170020249 6067599 2459271..2459420 1 NC_010468.1 PFAM: Hok/gef cell toxic protein; KEGG: ent:Ent638_4258 Hok/gef cell toxic protein; small toxic polypeptide 2459420 6067599 EcolC_2239 Escherichia coli ATCC 8739 small toxic polypeptide YP_001725203.1 2459271 D 481805 CDS YP_001725204.1 170020250 6065007 complement(2459492..2459665) 1 NC_010468.1 KEGG: ssn:SSON_1723 hypothetical protein; hypothetical protein 2459665 6065007 EcolC_2240 Escherichia coli ATCC 8739 hypothetical protein YP_001725204.1 2459492 R 481805 CDS YP_001725205.1 170020251 6065457 complement(2459910..2460440) 1 NC_010468.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 2460440 6065457 EcolC_2241 Escherichia coli ATCC 8739 cytochrome b561 YP_001725205.1 2459910 R 481805 CDS YP_001725206.1 170020252 6064371 2460629..2461630 1 NC_010468.1 KEGG: ssn:SSON_1725 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2461630 6064371 EcolC_2242 Escherichia coli ATCC 8739 glyceraldehyde-3-phosphate dehydrogenase YP_001725206.1 2460629 D 481805 CDS YP_001725207.1 170020253 6067691 complement(2461672..2463111) 1 NC_010468.1 NAD-linked; aldehyde dehydrogenase A 2463111 6067691 EcolC_2243 Escherichia coli ATCC 8739 aldehyde dehydrogenase A YP_001725207.1 2461672 R 481805 CDS YP_001725208.1 170020254 6065871 complement(2463308..2464108) 1 NC_010468.1 PFAM: protein of unknown function DUF218; KEGG: sbo:SBO_1673 hypothetical protein; hypothetical protein 2464108 6065871 EcolC_2244 Escherichia coli ATCC 8739 hypothetical protein YP_001725208.1 2463308 R 481805 CDS YP_001725209.1 170020255 6066961 complement(2464380..2468282) 1 NC_010468.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 2468282 6066961 EcolC_2245 Escherichia coli ATCC 8739 ATP-dependent RNA helicase HrpA YP_001725209.1 2464380 R 481805 CDS YP_001725210.1 170020256 6066957 2468483..2469088 1 NC_010468.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 2469088 6066957 EcolC_2246 Escherichia coli ATCC 8739 azoreductase YP_001725210.1 2468483 D 481805 CDS YP_001725211.1 170020257 6066948 complement(2469142..2470458) 1 NC_010468.1 PFAM: phosphoesterase PA-phosphatase related; Dual specificity protein phosphatase; SMART: Protein-tyrosine phosphatase, catalytic; KEGG: sbo:SBO_1676 putative enzyme; putative dual specificity phosphatase 2470458 6066948 EcolC_2247 Escherichia coli ATCC 8739 putative dual specificity phosphatase YP_001725211.1 2469142 R 481805 CDS YP_001725212.1 170020258 6066943 complement(2470448..2472205) 1 NC_010468.1 KEGG: sdy:SDY_1779 hypothetical protein; hypothetical protein 2472205 6066943 EcolC_2248 Escherichia coli ATCC 8739 hypothetical protein YP_001725212.1 2470448 R 481805 CDS YP_001725213.1 170020259 6065855 complement(2472221..2473117) 1 NC_010468.1 PFAM: phosphatidate cytidylyltransferase; KEGG: sfx:S1465 putative phosphatidate cytidiltransferase; phosphatidate cytidylyltransferase 2473117 6065855 EcolC_2249 Escherichia coli ATCC 8739 phosphatidate cytidylyltransferase YP_001725213.1 2472221 R 481805 CDS YP_001725214.1 170020260 6066104 complement(2473117..2473722) 1 NC_010468.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfv:SFV_1801 probable enzyme; CDP-alcohol phosphatidyltransferase 2473722 6066104 EcolC_2250 Escherichia coli ATCC 8739 CDP-alcohol phosphatidyltransferase YP_001725214.1 2473117 R 481805 CDS YP_001725215.1 170020261 6066938 complement(2473893..2476199) 1 NC_010468.1 KEGG: sfv:SFV_1802 hypothetical protein; hypothetical protein 2476199 6066938 EcolC_2251 Escherichia coli ATCC 8739 hypothetical protein YP_001725215.1 2473893 R 481805 CDS YP_001725216.1 170020262 6067705 complement(2476263..2477123) 1 NC_010468.1 PFAM: aldo/keto reductase; KEGG: cko:CKO_01438 hypothetical protein; putative oxidoreductase 2477123 6067705 EcolC_2252 Escherichia coli ATCC 8739 putative oxidoreductase YP_001725216.1 2476263 R 481805 CDS YP_001725217.1 170020263 6066951 complement(2480835..2481986) 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30; integrase catalytic subunit 2481986 6066951 EcolC_2254 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001725217.1 2480835 R 481805 CDS YP_001725218.1 170020264 6066936 complement(2485829..2486419) 1 NC_010468.1 TIGRFAM: phenylacetic acid degradation protein PaaY; KEGG: kpn:KPN_01481 phenylacetic acid degradation protein; putative transferase; phenylacetic acid degradation protein PaaY 2486419 6066936 EcolC_2255 Escherichia coli ATCC 8739 phenylacetic acid degradation protein PaaY YP_001725218.1 2485829 R 481805 CDS YP_001725219.1 170020265 6067050 complement(2486401..2487351) 1 NC_010468.1 TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: kpn:KPN_01480 transcriptional repressor for phenylacetic acid degradation; PaaX family transcriptional regulator 2487351 6067050 EcolC_2256 Escherichia coli ATCC 8739 PaaX family transcriptional regulator YP_001725219.1 2486401 R 481805 CDS YP_001725220.1 170020266 6067057 complement(2487452..2488765) 1 NC_010468.1 TIGRFAM: phenylacetate-CoA ligase; KEGG: kpn:KPN_01479 phenylacetate-CoA ligase; phenylacetate-CoA ligase 2488765 6067057 EcolC_2257 Escherichia coli ATCC 8739 phenylacetate-CoA ligase YP_001725220.1 2487452 R 481805 CDS YP_001725221.1 170020267 6067052 complement(2488792..2489997) 1 NC_010468.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 2489997 6067052 EcolC_2258 Escherichia coli ATCC 8739 beta-ketoadipyl CoA thiolase YP_001725221.1 2488792 R 481805 CDS YP_001725222.1 170020268 6067051 complement(2489997..2490419) 1 NC_010468.1 TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: kpn:KPN_01477 phenylacetic acid degradation protein; phenylacetic acid degradation protein PaaD 2490419 6067051 EcolC_2259 Escherichia coli ATCC 8739 phenylacetic acid degradation protein PaaD YP_001725222.1 2489997 R 481805 CDS YP_001725223.1 170020269 6067047 complement(2490409..2491836) 1 NC_010468.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 2491836 6067047 EcolC_2260 Escherichia coli ATCC 8739 3-hydroxyacyl-CoA dehydrogenase YP_001725223.1 2490409 R 481805 CDS YP_001725224.1 170020270 6067041 complement(2491838..2492626) 1 NC_010468.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2492626 6067041 EcolC_2261 Escherichia coli ATCC 8739 enoyl-CoA hydratase YP_001725224.1 2491838 R 481805 CDS YP_001725225.1 170020271 6067042 complement(2492626..2493393) 1 NC_010468.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: kpn:KPN_01474 probable enoyl-CoA hydratase; enoyl-CoA hydratase-isomerase 2493393 6067042 EcolC_2262 Escherichia coli ATCC 8739 enoyl-CoA hydratase-isomerase YP_001725225.1 2492626 R 481805 CDS YP_001725226.1 170020272 6067034 complement(2493390..2494460) 1 NC_010468.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: kpn:KPN_01473 probable phenylacetic acid degradation NADH oxidoreductase; phenylacetate-CoA oxygenase/reductase subunit PaaK 2494460 6067034 EcolC_2263 Escherichia coli ATCC 8739 phenylacetate-CoA oxygenase/reductase subunit PaaK YP_001725226.1 2493390 R 481805 CDS YP_001725227.1 170020273 6068712 complement(2494468..2494965) 1 NC_010468.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: kpn:KPN_01472 phenylacetic acid degradation protein; phenylacetate-CoA oxygenase subunit PaaJ 2494965 6068712 EcolC_2264 Escherichia coli ATCC 8739 phenylacetate-CoA oxygenase subunit PaaJ YP_001725227.1 2494468 R 481805 CDS YP_001725228.1 170020274 6064432 complement(2494980..2495726) 1 NC_010468.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01471 phenylacetic acid degradation protein; phenylacetate-CoA oxygenase subunit PaaI 2495726 6064432 EcolC_2265 Escherichia coli ATCC 8739 phenylacetate-CoA oxygenase subunit PaaI YP_001725228.1 2494980 R 481805 CDS YP_001725229.1 170020275 6065459 complement(2495735..2496022) 1 NC_010468.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 2496022 paaB 6065459 paaB Escherichia coli ATCC 8739 phenylacetate-CoA oxygenase subunit PaaB YP_001725229.1 2495735 R 481805 CDS YP_001725230.1 170020276 6067026 complement(2496034..2496963) 1 NC_010468.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 2496963 paaA 6067026 paaA Escherichia coli ATCC 8739 phenylacetate-CoA oxygenase subunit PaaA YP_001725230.1 2496034 R 481805 CDS YP_001725231.1 170020277 6067021 2497248..2499293 1 NC_010468.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 2499293 6067021 EcolC_2268 Escherichia coli ATCC 8739 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_001725231.1 2497248 D 481805 CDS YP_001725232.1 170020278 6067016 2499541..2501814 1 NC_010468.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 2501814 tynA 6067016 tynA Escherichia coli ATCC 8739 tyramine oxidase YP_001725232.1 2499541 D 481805 CDS YP_001725233.1 170020279 6067018 complement(2501873..2503372) 1 NC_010468.1 PFAM: Aldehyde Dehydrogenase_; KEGG: kpn:KPN_01455 phenylacetaldehyde dehydrogenase; phenylacetaldehyde dehydrogenase 2503372 6067018 EcolC_2270 Escherichia coli ATCC 8739 phenylacetaldehyde dehydrogenase YP_001725233.1 2501873 R 481805 CDS YP_001725234.1 170020280 6067011 2503608..2504513 1 NC_010468.1 activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 2504513 6067011 EcolC_2271 Escherichia coli ATCC 8739 DNA-binding transcriptional activator FeaR YP_001725234.1 2503608 D 481805 CDS YP_001725235.1 170020281 6067007 complement(2504685..2505011) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_1683 hypothetical protein; hypothetical protein 2505011 6067007 EcolC_2272 Escherichia coli ATCC 8739 hypothetical protein YP_001725235.1 2504685 R 481805 CDS YP_001725236.1 170020282 6067003 complement(2505019..2505204) 1 NC_010468.1 KEGG: ssn:SSON_1742 hypothetical protein; hypothetical protein 2505204 6067003 EcolC_2273 Escherichia coli ATCC 8739 hypothetical protein YP_001725236.1 2505019 R 481805 CDS YP_001725237.1 170020283 6068693 complement(2505201..2507840) 1 NC_010468.1 KEGG: sbo:SBO_1685 hypothetical protein; hypothetical protein 2507840 6068693 EcolC_2274 Escherichia coli ATCC 8739 hypothetical protein YP_001725237.1 2505201 R 481805 CDS YP_001725238.1 170020284 6066995 2508048..2509037 1 NC_010468.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1744 fermentative D-lactate dehydrogenase, NAD-dependent; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 2509037 6066995 EcolC_2275 Escherichia coli ATCC 8739 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_001725238.1 2508048 D 481805 CDS YP_001725239.1 170020285 6066984 2509148..2509570 1 NC_010468.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sbo:SBO_1687 heat shock protein HslJ; heat-inducible protein 2509570 6066984 EcolC_2276 Escherichia coli ATCC 8739 heat-inducible protein YP_001725239.1 2509148 D 481805 CDS YP_001725240.1 170020286 6066982 complement(2509567..2509833) 1 NC_010468.1 KEGG: sdy:SDY_1462 hypothetical protein; hypothetical protein 2509833 6066982 EcolC_2277 Escherichia coli ATCC 8739 hypothetical protein YP_001725240.1 2509567 R 481805 CDS YP_001725241.1 170020287 6066979 2510107..2513631 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sbo:SBO_1688 putative oxidoreductase, Fe-S subunit; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 2513631 6066979 EcolC_2278 Escherichia coli ATCC 8739 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein YP_001725241.1 2510107 D 481805 CDS YP_001725242.1 170020288 6068729 2513998..2515131 1 NC_010468.1 PFAM: porin Gram-negative type; KEGG: sbo:SBO_1689 putative outer membrane protein; porin 2515131 6068729 EcolC_2279 Escherichia coli ATCC 8739 porin YP_001725242.1 2513998 D 481805 CDS YP_001725243.1 170020289 6066970 2515272..2515706 1 NC_010468.1 PFAM: UspA domain protein; KEGG: sdy:SDY_1458 putative filament protein; UspA domain-containing protein 2515706 6066970 EcolC_2280 Escherichia coli ATCC 8739 UspA domain-containing protein YP_001725243.1 2515272 D 481805 CDS YP_001725244.1 170020290 6066968 2515883..2516818 1 NC_010468.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 2516818 6066968 EcolC_2281 Escherichia coli ATCC 8739 C32 tRNA thiolase YP_001725244.1 2515883 D 481805 CDS YP_001725245.1 170020291 6066967 complement(2516947..2518320) 1 NC_010468.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 2518320 6066967 EcolC_2282 Escherichia coli ATCC 8739 ATP-dependent RNA helicase DbpA YP_001725245.1 2516947 R 481805 CDS YP_001725246.1 170020292 6066965 complement(2518798..2519781) 1 NC_010468.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: sdy:SDY_1424 hypothetical protein; zinc transporter 2519781 zntB 6066965 zntB Escherichia coli ATCC 8739 zinc transporter YP_001725246.1 2518798 R 481805 CDS YP_001725247.1 170020293 6064355 2520036..2521268 1 NC_010468.1 KEGG: sbo:SBO_1720 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAS/PAC sensor-containing diguanylate cyclase 2521268 6064355 EcolC_2284 Escherichia coli ATCC 8739 PAS/PAC sensor-containing diguanylate cyclase YP_001725247.1 2520036 D 481805 CDS YP_001725248.1 170020294 6064364 complement(2521289..2521852) 1 NC_010468.1 PFAM: Smr protein/MutS2; KEGG: ssn:SSON_1791 hypothetical protein; Smr protein/MutS2 2521852 6064364 EcolC_2285 Escherichia coli ATCC 8739 Smr protein/MutS2 YP_001725248.1 2521289 R 481805 CDS YP_001725249.1 170020295 6066962 complement(2522182..2523090) 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1792 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 2523090 6066962 EcolC_2286 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001725249.1 2522182 R 481805 CDS YP_001725250.1 170020296 6066959 2523266..2524576 1 NC_010468.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1793 putative aminohydrolase; amidohydrolase 2524576 6066959 EcolC_2287 Escherichia coli ATCC 8739 amidohydrolase YP_001725250.1 2523266 D 481805 CDS YP_001725251.1 170020297 6066958 2524576..2526021 1 NC_010468.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1794 hypothetical protein; amidohydrolase 2526021 6066958 EcolC_2288 Escherichia coli ATCC 8739 amidohydrolase YP_001725251.1 2524576 D 481805 CDS YP_001725252.1 170020298 6065413 2526055..2527581 1 NC_010468.1 TIGRFAM: AbgT transporter family; PFAM: AbgT putative transporter; KEGG: sbo:SBO_1725 putative pump protein (transport); putative aminobenzoyl-glutamate transporter 2527581 abgT 6065413 abgT Escherichia coli ATCC 8739 putative aminobenzoyl-glutamate transporter YP_001725252.1 2526055 D 481805 CDS YP_001725253.1 170020299 6068733 2527592..2528107 1 NC_010468.1 KEGG: sfv:SFV_1824 O-6-alkylguanine-DNA/cysteine-protein methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 2528107 6068733 EcolC_2290 Escherichia coli ATCC 8739 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_001725253.1 2527592 D 481805 CDS YP_001725254.1 170020300 6066838 2528302..2529054 1 NC_010468.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 2529054 6066838 EcolC_2291 Escherichia coli ATCC 8739 fumarate/nitrate reduction transcriptional regulator YP_001725254.1 2528302 D 481805 CDS YP_001725255.1 170020301 6066955 2529206..2530156 1 NC_010468.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 2530156 6066955 EcolC_2292 Escherichia coli ATCC 8739 universal stress protein UspE YP_001725255.1 2529206 D 481805 CDS YP_001725256.1 170020302 6066947 complement(2530206..2530463) 1 NC_010468.1 KEGG: ssn:SSON_1801 hypothetical protein; hypothetical protein 2530463 6066947 EcolC_2293 Escherichia coli ATCC 8739 hypothetical protein YP_001725256.1 2530206 R 481805 CDS YP_001725257.1 170020303 6066869 2530707..2531738 1 NC_010468.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_1732 hypothetical protein; mechanosensitive ion channel MscS 2531738 6066869 EcolC_2294 Escherichia coli ATCC 8739 mechanosensitive ion channel MscS YP_001725257.1 2530707 D 481805 CDS YP_001725258.1 170020304 6068731 complement(2531789..2533402) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1804 putative transport periplasmic protein; extracellular solute-binding protein 2533402 6068731 EcolC_2295 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725258.1 2531789 R 481805 CDS YP_001725259.1 170020305 6066941 complement(2533739..2534638) 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1734 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2534638 6066941 EcolC_2296 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725259.1 2533739 R 481805 CDS YP_001725260.1 170020306 6066935 2534776..2535696 1 NC_010468.1 PFAM: peptidase S15; KEGG: sfl:SF1337 hypothetical protein; peptidase S15 2535696 6066935 EcolC_2297 Escherichia coli ATCC 8739 peptidase S15 YP_001725260.1 2534776 D 481805 CDS YP_001725261.1 170020307 6067056 2536032..2536760 1 NC_010468.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: sbo:SBO_1744 putative carboxypeptidase; murein peptide amidase A 2536760 6067056 EcolC_2299 Escherichia coli ATCC 8739 murein peptide amidase A YP_001725261.1 2536032 D 481805 CDS YP_001725262.1 170020308 6066945 complement(2536735..2537700) 1 NC_010468.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sfv:SFV_1341 putative muconate cycloisomerase I; mandelate racemase/muconate lactonizing protein 2537700 6066945 EcolC_2300 Escherichia coli ATCC 8739 mandelate racemase/muconate lactonizing protein YP_001725262.1 2536735 R 481805 CDS YP_001725263.1 170020309 6067015 2537819..2538325 1 NC_010468.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2538325 tpx 6067015 tpx Escherichia coli ATCC 8739 thiol peroxidase YP_001725263.1 2537819 D 481805 CDS YP_001725264.1 170020310 6066954 complement(2538369..2539910) 1 NC_010468.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 2539910 6066954 EcolC_2302 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator TyrR YP_001725264.1 2538369 R 481805 CDS YP_001725265.1 170020311 6067006 complement(2540058..2541119) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sfv:SFV_1338 hypothetical protein; hypothetical protein 2541119 6067006 EcolC_2303 Escherichia coli ATCC 8739 hypothetical protein YP_001725265.1 2540058 R 481805 CDS YP_001725266.1 170020312 6066975 complement(2541116..2542513) 1 NC_010468.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: sbo:SBO_1749 YcjX; hypothetical protein 2542513 6066975 EcolC_2304 Escherichia coli ATCC 8739 hypothetical protein YP_001725266.1 2541116 R 481805 CDS YP_001725267.1 170020313 6066937 2542669..2543667 1 NC_010468.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sfx:S1409 putative LacI-type transcriptional regulator; LacI family transcriptional regulator 2543667 6066937 EcolC_2305 Escherichia coli ATCC 8739 LacI family transcriptional regulator YP_001725267.1 2542669 D 481805 CDS YP_001725268.1 170020314 6066929 complement(2543778..2544683) 1 NC_010468.1 KEGG: ent:Ent638_2156 outer membrane protein G precursor; outer membrane protein G 2544683 6066929 EcolC_2306 Escherichia coli ATCC 8739 outer membrane protein G YP_001725268.1 2543778 R 481805 CDS YP_001725269.1 170020315 6068307 complement(2544728..2545810) 1 NC_010468.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sfv:SFV_1334 putative ATP-binding component of a transport system; ABC transporter-like protein 2545810 6068307 EcolC_2307 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725269.1 2544728 R 481805 CDS YP_001725270.1 170020316 6067488 complement(2545824..2546483) 1 NC_010468.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ssn:SSON_1823 putative beta-phosphoglucomutase; beta-phosphoglucomutase 2546483 6067488 EcolC_2308 Escherichia coli ATCC 8739 beta-phosphoglucomutase YP_001725270.1 2545824 R 481805 CDS YP_001725271.1 170020317 6068708 complement(2546480..2548747) 1 NC_010468.1 PFAM: glycoside hydrolase family 65 domain protein; glycoside hydrolase family 65 central catalytic; KEGG: ssn:SSON_1824 hypothetical protein; Kojibiose phosphorylase 2548747 6068708 EcolC_2309 Escherichia coli ATCC 8739 Kojibiose phosphorylase YP_001725271.1 2546480 R 481805 CDS YP_001725272.1 170020318 6065658 complement(2548744..2549799) 1 NC_010468.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ssn:SSON_1825 putative dehydrogenase; oxidoreductase domain-containing protein 2549799 6065658 EcolC_2310 Escherichia coli ATCC 8739 oxidoreductase domain-containing protein YP_001725272.1 2548744 R 481805 CDS YP_001725273.1 170020319 6064564 complement(2549809..2550597) 1 NC_010468.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ssn:SSON_1826 putative transient receptor potential locus; xylose isomerase domain-containing protein 2550597 6064564 EcolC_2311 Escherichia coli ATCC 8739 xylose isomerase domain-containing protein YP_001725273.1 2549809 R 481805 CDS YP_001725274.1 170020320 6067040 complement(2550616..2551668) 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1329 putative oxidoreductase; alcohol dehydrogenase 2551668 6067040 EcolC_2312 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001725274.1 2550616 R 481805 CDS YP_001725275.1 170020321 6066886 complement(2551699..2552541) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_1328 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 2552541 6066886 EcolC_2313 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725275.1 2551699 R 481805 CDS YP_001725276.1 170020322 6066695 complement(2552528..2553409) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1829 putative binding-protein dependent transport protein; binding-protein-dependent transport system inner membrane protein 2553409 6066695 EcolC_2314 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725276.1 2552528 R 481805 CDS YP_001725277.1 170020323 6065983 complement(2553430..2554722) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1830 putative transport periplasmic protein; extracellular solute-binding protein 2554722 6065983 EcolC_2315 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725277.1 2553430 R 481805 CDS YP_001725278.1 170020324 6065908 complement(2554736..2556415) 1 NC_010468.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ent:Ent638_2165 alpha amylase, catalytic region; alpha amylase 2556415 6065908 EcolC_2316 Escherichia coli ATCC 8739 alpha amylase YP_001725278.1 2554736 R 481805 CDS YP_001725279.1 170020325 6065440 complement(2556628..2556942) 1 NC_010468.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 2556942 6065440 EcolC_2317 Escherichia coli ATCC 8739 thiosulfate:cyanide sulfurtransferase YP_001725279.1 2556628 R 481805 CDS YP_001725280.1 170020326 6064838 complement(2557017..2557238) 1 NC_010468.1 TIGRFAM: phage shock protein PspD; PFAM: shock protein PspD; KEGG: sdy:SDY_1937 phage shock protein; peripheral inner membrane phage-shock protein 2557238 6064838 EcolC_2318 Escherichia coli ATCC 8739 peripheral inner membrane phage-shock protein YP_001725280.1 2557017 R 481805 CDS YP_001725281.1 170020327 6065789 complement(2557247..2557606) 1 NC_010468.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 2557606 6065789 EcolC_2319 Escherichia coli ATCC 8739 DNA-binding transcriptional activator PspC YP_001725281.1 2557247 R 481805 CDS YP_001725282.1 170020328 6064745 complement(2557606..2557830) 1 NC_010468.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 2557830 pspB 6064745 pspB Escherichia coli ATCC 8739 phage shock protein B YP_001725282.1 2557606 R 481805 CDS YP_001725283.1 170020329 6065182 complement(2557884..2558552) 1 NC_010468.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 2558552 6065182 EcolC_2321 Escherichia coli ATCC 8739 phage shock protein PspA YP_001725283.1 2557884 R 481805 CDS YP_001725284.1 170020330 6067094 2558719..2559696 1 NC_010468.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 2559696 pspF 6067094 pspF Escherichia coli ATCC 8739 phage shock protein operon transcriptional activator YP_001725284.1 2558719 D 481805 CDS YP_001725285.1 170020331 6066303 complement(2559816..2561081) 1 NC_010468.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 2561081 6066303 EcolC_2323 Escherichia coli ATCC 8739 4-aminobutyrate transaminase YP_001725285.1 2559816 R 481805 CDS YP_001725286.1 170020332 6066648 complement(2561119..2562399) 1 NC_010468.1 PFAM: FAD dependent oxidoreductase; KEGG: ssn:SSON_1839 probable oxidoreductase; FAD dependent oxidoreductase 2562399 6066648 EcolC_2324 Escherichia coli ATCC 8739 FAD dependent oxidoreductase YP_001725286.1 2561119 R 481805 CDS YP_001725287.1 170020333 6067383 complement(2562401..2563888) 1 NC_010468.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 2563888 6067383 EcolC_2325 Escherichia coli ATCC 8739 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_001725287.1 2562401 R 481805 CDS YP_001725288.1 170020334 6065253 complement(2564163..2564720) 1 NC_010468.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 2564720 6065253 EcolC_2326 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor PuuR YP_001725288.1 2564163 R 481805 CDS YP_001725289.1 170020335 6065753 complement(2564747..2565511) 1 NC_010468.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 2565511 puuD 6065753 puuD Escherichia coli ATCC 8739 gamma-glutamyl-gamma-aminobutyrate hydrolase YP_001725289.1 2564747 R 481805 CDS YP_001725290.1 170020336 6065435 2565723..2567141 1 NC_010468.1 PFAM: glutamine synthetase catalytic region; KEGG: sfx:S1384 putative glutamine synthetase; glutamine synthetase 2567141 6065435 EcolC_2328 Escherichia coli ATCC 8739 glutamine synthetase YP_001725290.1 2565723 D 481805 CDS YP_001725291.1 170020337 6065083 2567444..2568829 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1766 putative amino acid/amine transport protein; amino acid permease-associated protein 2568829 6065083 EcolC_2329 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001725291.1 2567444 D 481805 CDS YP_001725292.1 170020338 6065237 2568963..2569208 1 NC_010468.1 KEGG: ssn:SSON_1845 hypothetical protein; hypothetical protein 2569208 6065237 EcolC_2330 Escherichia coli ATCC 8739 hypothetical protein YP_001725292.1 2568963 D 481805 CDS YP_001725293.1 170020339 6066752 2569521..2571164 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1768 SapA; extracellular solute-binding protein 2571164 6066752 EcolC_2331 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725293.1 2569521 D 481805 CDS YP_001725294.1 170020340 6068715 2571161..2572126 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1769 SapB; binding-protein-dependent transport system inner membrane protein 2572126 6068715 EcolC_2332 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725294.1 2571161 D 481805 CDS YP_001725295.1 170020341 6067196 2572113..2573003 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1770 SapC; binding-protein-dependent transport system inner membrane protein 2573003 6067196 EcolC_2333 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725295.1 2572113 D 481805 CDS YP_001725296.1 170020342 6065568 2573003..2573995 1 NC_010468.1 KEGG: ssn:SSON_1849 putative ATP-binding protein of peptide transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2573995 6065568 EcolC_2334 Escherichia coli ATCC 8739 oligopeptide/dipeptide ABC transporter ATPase YP_001725296.1 2573003 D 481805 CDS YP_001725297.1 170020343 6066077 2573997..2574803 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_1772 putative ATP-binding protein of peptide transport system; ABC transporter-like protein 2574803 6066077 EcolC_2335 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725297.1 2573997 D 481805 CDS YP_001725298.1 170020344 6066441 2574871..2575224 1 NC_010468.1 PFAM: protein of unknown function DUF559; KEGG: sbo:SBO_1773 hypothetical protein; hypothetical protein 2575224 6066441 EcolC_2336 Escherichia coli ATCC 8739 hypothetical protein YP_001725298.1 2574871 D 481805 CDS YP_001725299.1 170020345 6067615 2575592..2576380 1 NC_010468.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 2576380 6067615 EcolC_2337 Escherichia coli ATCC 8739 enoyl-(acyl carrier protein) reductase YP_001725299.1 2575592 D 481805 CDS YP_001725300.1 170020346 6064690 2576524..2577651 1 NC_010468.1 KEGG: sbo:SBO_1775 putative oxidoreductase; putative oxidoreductase 2577651 6064690 EcolC_2338 Escherichia coli ATCC 8739 putative oxidoreductase YP_001725300.1 2576524 D 481805 CDS YP_001725301.1 170020347 6065623 2577719..2579653 1 NC_010468.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 2579653 6065623 EcolC_2339 Escherichia coli ATCC 8739 exoribonuclease II YP_001725301.1 2577719 D 481805 CDS YP_001725302.1 170020348 6064427 2579887..2581872 1 NC_010468.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 2581872 6064427 EcolC_2340 Escherichia coli ATCC 8739 RNase II stability modulator YP_001725302.1 2579887 D 481805 CDS YP_001725303.1 170020349 6064681 2582019..2582192 1 NC_010468.1 KEGG: sdy:SDY_1362 hypothetical protein; hypothetical protein 2582192 6064681 EcolC_2341 Escherichia coli ATCC 8739 hypothetical protein YP_001725303.1 2582019 D 481805 CDS YP_001725304.1 170020350 6067351 2582282..2583031 1 NC_010468.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sdy:SDY_1361 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 2583031 6067351 EcolC_2342 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001725304.1 2582282 D 481805 CDS YP_001725305.1 170020351 6064765 2583300..2583518 1 NC_010468.1 KEGG: sbo:SBO_1781 osmotically inducible lipoprotein; lipoprotein 2583518 6064765 EcolC_2343 Escherichia coli ATCC 8739 lipoprotein YP_001725305.1 2583300 D 481805 CDS YP_001725306.1 170020352 6065732 complement(2583644..2583970) 1 NC_010468.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 2583970 6065732 EcolC_2344 Escherichia coli ATCC 8739 translation initiation factor Sui1 YP_001725306.1 2583644 R 481805 CDS YP_001725307.1 170020353 6066877 complement(2583970..2584707) 1 NC_010468.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2584707 6066877 EcolC_2345 Escherichia coli ATCC 8739 orotidine 5'-phosphate decarboxylase YP_001725307.1 2583970 R 481805 CDS YP_001725308.1 170020354 6065641 complement(2584900..2586069) 1 NC_010468.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ssn:SSON_1860 putative heat shock protein; hypothetical protein 2586069 6065641 EcolC_2346 Escherichia coli ATCC 8739 hypothetical protein YP_001725308.1 2584900 R 481805 CDS YP_001725309.1 170020355 6066278 complement(2586076..2586384) 1 NC_010468.1 PFAM: protein of unknown function DUF1049; KEGG: sbo:SBO_1785 hypothetical protein; hypothetical protein 2586384 6066278 EcolC_2347 Escherichia coli ATCC 8739 hypothetical protein YP_001725309.1 2586076 R 481805 CDS YP_001725310.1 170020356 6067009 complement(2586533..2587297) 1 NC_010468.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: sdy:SDY_1354 non-essential phosphatidylglycerophosphate phosphatase, membrane bound; phosphatidylglycerophosphatase B 2587297 6067009 EcolC_2348 Escherichia coli ATCC 8739 phosphatidylglycerophosphatase B YP_001725310.1 2586533 R 481805 CDS YP_001725311.1 170020357 6067261 2587467..2588057 1 NC_010468.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 2588057 ribA 6067261 ribA Escherichia coli ATCC 8739 GTP cyclohydrolase II YP_001725311.1 2587467 D 481805 CDS YP_001725312.1 170020358 6065173 complement(2588121..2590796) 1 NC_010468.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 2590796 6065173 EcolC_2350 Escherichia coli ATCC 8739 aconitate hydratase YP_001725312.1 2588121 R 481805 CDS YP_001725313.1 170020359 6067143 complement(2591169..2591336) 1 NC_010468.1 KEGG: ssn:SSON_1865 hypothetical protein; hypothetical protein 2591336 6067143 EcolC_2351 Escherichia coli ATCC 8739 hypothetical protein YP_001725313.1 2591169 R 481805 CDS YP_001725314.1 170020360 6066683 complement(2591339..2591467) 1 NC_010468.1 KEGG: sdy:SDY_1348 hypothetical protein; hypothetical protein 2591467 6066683 EcolC_2352 Escherichia coli ATCC 8739 hypothetical protein YP_001725314.1 2591339 R 481805 CDS YP_001725315.1 170020361 6065867 complement(2591798..2592772) 1 NC_010468.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 2592772 cysB 6065867 cysB Escherichia coli ATCC 8739 transcriptional regulator CysB YP_001725315.1 2591798 R 481805 CDS YP_001725316.1 170020362 6065617 complement(2592982..2595579) 1 NC_010468.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 2595579 6065617 EcolC_2354 Escherichia coli ATCC 8739 DNA topoisomerase I YP_001725316.1 2592982 R 481805 CDS YP_001725317.1 170020363 6066833 2595959..2596210 1 NC_010468.1 KEGG: sdy:SDY_1343 hypothetical protein; hypothetical protein 2596210 6066833 EcolC_2355 Escherichia coli ATCC 8739 hypothetical protein YP_001725317.1 2595959 D 481805 CDS YP_001725318.1 170020364 6064794 complement(2596246..2597295) 1 NC_010468.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 2597295 6064794 EcolC_2356 Escherichia coli ATCC 8739 putative periplasmic protease YP_001725318.1 2596246 R 481805 CDS YP_001725319.1 170020365 6066231 2597515..2598273 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sdy:SDY_1341 putative oxidoreductase; short chain dehydrogenase 2598273 6066231 EcolC_2357 Escherichia coli ATCC 8739 short chain dehydrogenase YP_001725319.1 2597515 D 481805 CDS YP_001725320.1 170020366 6065609 2598270..2598860 1 NC_010468.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 2598860 6065609 EcolC_2358 Escherichia coli ATCC 8739 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001725320.1 2598270 D 481805 CDS YP_001725321.1 170020367 6065390 complement(2598900..2599775) 1 NC_010468.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 2599775 6065390 EcolC_2359 Escherichia coli ATCC 8739 23S rRNA pseudouridylate synthase B YP_001725321.1 2598900 R 481805 CDS YP_001725322.1 170020368 6064955 complement(2599986..2601881) 1 NC_010468.1 KEGG: sbo:SBO_1798 hypothetical protein; hypothetical protein 2601881 6064955 EcolC_2360 Escherichia coli ATCC 8739 hypothetical protein YP_001725322.1 2599986 R 481805 CDS YP_001725323.1 170020369 6065876 complement(2601909..2602529) 1 NC_010468.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: sbo:SBO_1799 hypothetical protein; hypothetical protein 2602529 6065876 EcolC_2361 Escherichia coli ATCC 8739 hypothetical protein YP_001725323.1 2601909 R 481805 CDS YP_001725324.1 170020370 6065135 complement(2602526..2603407) 1 NC_010468.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfx:S1354 putative enzyme; phosphotransferase domain-containing protein 2603407 6065135 EcolC_2362 Escherichia coli ATCC 8739 phosphotransferase domain-containing protein YP_001725324.1 2602526 R 481805 CDS YP_001725325.1 170020371 6065139 2603681..2605243 1 NC_010468.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 2605243 6065139 EcolC_2363 Escherichia coli ATCC 8739 anthranilate synthase component I YP_001725325.1 2603681 D 481805 CDS YP_001725326.1 170020372 6064879 2605243..2606838 1 NC_010468.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 2606838 6064879 EcolC_2364 Escherichia coli ATCC 8739 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_001725326.1 2605243 D 481805 CDS YP_001725327.1 170020373 6066108 2606842..2608200 1 NC_010468.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 2608200 6066108 EcolC_2365 Escherichia coli ATCC 8739 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001725327.1 2606842 D 481805 CDS YP_001725328.1 170020374 6065466 2608212..2609405 1 NC_010468.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2609405 6065466 EcolC_2366 Escherichia coli ATCC 8739 tryptophan synthase subunit beta YP_001725328.1 2608212 D 481805 CDS YP_001725329.1 170020375 6066005 2609405..2610211 1 NC_010468.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2610211 trpA 6066005 trpA Escherichia coli ATCC 8739 tryptophan synthase subunit alpha YP_001725329.1 2609405 D 481805 CDS YP_001725330.1 170020376 6066994 2610592..2610771 1 NC_010468.1 KEGG: sfv:SFV_1273 hypothetical protein; hypothetical protein 2610771 6066994 EcolC_2368 Escherichia coli ATCC 8739 hypothetical protein YP_001725330.1 2610592 D 481805 CDS YP_001725331.1 170020377 6067029 2610857..2611357 1 NC_010468.1 PFAM: protein of unknown function DUF892; KEGG: sfv:SFV_1272 putative structural proteins; hypothetical protein 2611357 6067029 EcolC_2369 Escherichia coli ATCC 8739 hypothetical protein YP_001725331.1 2610857 D 481805 CDS YP_001725332.1 170020378 6066632 2611403..2611909 1 NC_010468.1 PFAM: protein of unknown function DUF892; KEGG: sfv:SFV_1271 hypothetical protein; hypothetical protein 2611909 6066632 EcolC_2370 Escherichia coli ATCC 8739 hypothetical protein YP_001725332.1 2611403 D 481805 CDS YP_001725333.1 170020379 6065206 complement(2611969..2612607) 1 NC_010468.1 receptor for colicin S4; outer membrane protein W 2612607 6065206 EcolC_2371 Escherichia coli ATCC 8739 outer membrane protein W YP_001725333.1 2611969 R 481805 CDS YP_001725334.1 170020380 6067570 2612964..2613707 1 NC_010468.1 PFAM: protein of unknown function UPF0259; KEGG: ssn:SSON_1911 hypothetical protein; hypothetical protein 2613707 6067570 EcolC_2372 Escherichia coli ATCC 8739 hypothetical protein YP_001725334.1 2612964 D 481805 CDS YP_001725335.1 170020381 6064963 2613737..2614276 1 NC_010468.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 2614276 6064963 EcolC_2373 Escherichia coli ATCC 8739 intracellular septation protein A YP_001725335.1 2613737 D 481805 CDS YP_001725336.1 170020382 6064911 2614381..2614779 1 NC_010468.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 2614779 6064911 EcolC_2374 Escherichia coli ATCC 8739 acyl-CoA thioester hydrolase YP_001725336.1 2614381 D 481805 CDS YP_001725337.1 170020383 6066248 complement(2614819..2615553) 1 NC_010468.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 2615553 6066248 EcolC_2375 Escherichia coli ATCC 8739 transporter YP_001725337.1 2614819 R 481805 CDS YP_001725338.1 170020384 6066694 2615762..2616058 1 NC_010468.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 2616058 6066694 EcolC_2376 Escherichia coli ATCC 8739 YciI-like protein YP_001725338.1 2615762 D 481805 CDS YP_001725339.1 170020385 6067152 2616358..2617611 1 NC_010468.1 PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: sbo:SBO_1817 putative potassium channel protein; voltage-gated potassium channel 2617611 6067152 EcolC_2377 Escherichia coli ATCC 8739 voltage-gated potassium channel YP_001725339.1 2616358 D 481805 CDS YP_001725340.1 170020386 6065527 complement(2617666..2617839) 1 NC_010468.1 KEGG: cko:CKO_01327 hypothetical protein; hypothetical protein 2617839 6065527 EcolC_2378 Escherichia coli ATCC 8739 hypothetical protein YP_001725340.1 2617666 R 481805 CDS YP_001725341.1 170020387 6067575 2617982..2619442 1 NC_010468.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 2619442 cls 6067575 cls Escherichia coli ATCC 8739 cardiolipin synthetase YP_001725341.1 2617982 D 481805 CDS YP_001725342.1 170020388 6064764 2619477..2619806 1 NC_010468.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 2619806 6064764 EcolC_2380 Escherichia coli ATCC 8739 dsDNA-mimic protein YP_001725342.1 2619477 D 481805 CDS YP_001725343.1 170020389 6067523 complement(2619859..2620863) 1 NC_010468.1 KEGG: sfv:SFV_1259 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2620863 6067523 EcolC_2381 Escherichia coli ATCC 8739 oligopeptide/dipeptide ABC transporter ATPase YP_001725343.1 2619859 R 481805 CDS YP_001725344.1 170020390 6065869 complement(2620860..2621873) 1 NC_010468.1 KEGG: sfv:SFV_1258 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide transporter ATP-binding protein 2621873 oppD 6065869 oppD Escherichia coli ATCC 8739 oligopeptide transporter ATP-binding protein YP_001725344.1 2620860 R 481805 CDS YP_001725345.1 170020391 6064793 complement(2621885..2622793) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1935 oligopeptide transport permease protein-like protein; binding-protein-dependent transport system inner membrane protein 2622793 6064793 EcolC_2383 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725345.1 2621885 R 481805 CDS YP_001725346.1 170020392 6066603 complement(2622808..2623728) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1823 oligopeptide transport permease protein; oligopeptide transporter permease 2623728 oppB 6066603 oppB Escherichia coli ATCC 8739 oligopeptide transporter permease YP_001725346.1 2622808 R 481805 CDS YP_001725347.1 170020393 6067119 complement(2623814..2625490) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1824 oligopeptide transport periplasmic binding protein; extracellular solute-binding protein 2625490 6067119 EcolC_2385 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725347.1 2623814 R 481805 CDS YP_001725348.1 170020394 6067583 complement(2626183..2626830) 1 NC_010468.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ssn:SSON_1938 putative channel protein; hypothetical protein 2626830 6067583 EcolC_2386 Escherichia coli ATCC 8739 hypothetical protein YP_001725348.1 2626183 R 481805 CDS YP_001725349.1 170020395 6067039 2627307..2629982 1 NC_010468.1 PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: sdy:SDY_1295 CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase/pyruvate-formate-lyase deactivase; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2629982 6067039 EcolC_2387 Escherichia coli ATCC 8739 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_001725349.1 2627307 D 481805 CDS YP_001725350.1 170020396 6065970 complement(2631284..2631901) 1 NC_010468.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 2631901 6065970 EcolC_2389 Escherichia coli ATCC 8739 thymidine kinase YP_001725350.1 2631284 R 481805 CDS YP_001725351.1 170020397 6066062 2632506..2632919 1 NC_010468.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sdy:SDY_1289 DNA-binding protein HLP-II; global DNA-binding transcriptional dual regulator H-NS 2632919 6066062 EcolC_2390 Escherichia coli ATCC 8739 global DNA-binding transcriptional dual regulator H-NS YP_001725351.1 2632506 D 481805 CDS YP_001725352.1 170020398 6067481 complement(2633063..2633971) 1 NC_010468.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 2633971 6067481 EcolC_2391 Escherichia coli ATCC 8739 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_001725352.1 2633063 R 481805 CDS YP_001725353.1 170020399 6066321 complement(2634173..2635186) 1 NC_010468.1 PFAM: response regulator receiver; KEGG: sdy:SDY_1287 Hnr protein; response regulator of RpoS 2635186 6066321 EcolC_2392 Escherichia coli ATCC 8739 response regulator of RpoS YP_001725353.1 2634173 R 481805 CDS YP_001725354.1 170020400 6066484 complement(2635278..2636222) 1 NC_010468.1 PFAM: Patatin; KEGG: ssn:SSON_1945 hypothetical protein; hypothetical protein 2636222 6066484 EcolC_2393 Escherichia coli ATCC 8739 hypothetical protein YP_001725354.1 2635278 R 481805 CDS YP_001725355.1 170020401 6066430 2636296..2636754 1 NC_010468.1 PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1836 hypothetical protein; hypothetical protein 2636754 6066430 EcolC_2394 Escherichia coli ATCC 8739 hypothetical protein YP_001725355.1 2636296 D 481805 CDS YP_001725356.1 170020402 6065755 2636804..2637646 1 NC_010468.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 2637646 purU 6065755 purU Escherichia coli ATCC 8739 formyltetrahydrofolate deformylase YP_001725356.1 2636804 D 481805 CDS YP_001725357.1 170020403 6064342 complement(2639081..2639758) 1 NC_010468.1 KEGG: ssn:SSON_1949 nitrate reductase 1, cytochrome b(NR), gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit; respiratory nitrate reductase subunit gamma 2639758 6064342 EcolC_2396 Escherichia coli ATCC 8739 respiratory nitrate reductase subunit gamma YP_001725357.1 2639081 R 481805 CDS YP_001725358.1 170020404 6066825 complement(2639758..2640468) 1 NC_010468.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: ssn:SSON_1950 nitrate reductase 1, delta subunit, assembly function; nitrate reductase molybdenum cofactor assembly chaperone 2640468 6066825 EcolC_2397 Escherichia coli ATCC 8739 nitrate reductase molybdenum cofactor assembly chaperone YP_001725358.1 2639758 R 481805 CDS YP_001725359.1 170020405 6064341 complement(2640465..2642003) 1 NC_010468.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: sbo:SBO_1841 nitrate reductase 1 beta subunit; nitrate reductase subunit beta 2642003 6064341 EcolC_2398 Escherichia coli ATCC 8739 nitrate reductase subunit beta YP_001725359.1 2640465 R 481805 CDS YP_001725360.1 170020406 6066859 complement(2642000..2645743) 1 NC_010468.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1240 nitrate reductase 1, alpha subunit; nitrate reductase subunit alpha 2645743 6066859 EcolC_2399 Escherichia coli ATCC 8739 nitrate reductase subunit alpha YP_001725360.1 2642000 R 481805 CDS YP_001725361.1 170020407 6064484 complement(2646259..2647650) 1 NC_010468.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1843 nitrite extrusion protein; nitrite transporter 2647650 6064484 EcolC_2400 Escherichia coli ATCC 8739 nitrite transporter YP_001725361.1 2646259 R 481805 CDS YP_001725362.1 170020408 6066824 2647989..2649785 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sfv:SFV_1238 nitrate/nitrate sensor, histidine protein kinase; nitrate/nitrite sensor protein NarX 2649785 6066824 EcolC_2401 Escherichia coli ATCC 8739 nitrate/nitrite sensor protein NarX YP_001725362.1 2647989 D 481805 CDS YP_001725363.1 170020409 6066788 2649778..2650428 1 NC_010468.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 2650428 6066788 EcolC_2402 Escherichia coli ATCC 8739 transcriptional regulator NarL YP_001725363.1 2649778 D 481805 CDS YP_001725364.1 170020410 6068594 complement(2650429..2651859) 1 NC_010468.1 KEGG: ssn:SSON_1957 putative factor; hypothetical protein 2651859 6068594 EcolC_2403 Escherichia coli ATCC 8739 hypothetical protein YP_001725364.1 2650429 R 481805 CDS YP_001725365.1 170020411 6066709 2652009..2652362 1 NC_010468.1 PFAM: DsrE family protein; KEGG: sdy:SDY_1271 hypothetical protein; DsrE family protein 2652362 6066709 EcolC_2404 Escherichia coli ATCC 8739 DsrE family protein YP_001725365.1 2652009 D 481805 CDS YP_001725366.1 170020412 6066757 complement(2652406..2653122) 1 NC_010468.1 PFAM: ChaC family protein; KEGG: sbo:SBO_1848 cation transport regulator; ChaC family protein 2653122 6066757 EcolC_2405 Escherichia coli ATCC 8739 ChaC family protein YP_001725366.1 2652406 R 481805 CDS YP_001725367.1 170020413 6066678 complement(2653259..2653489) 1 NC_010468.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 2653489 chaB 6066678 chaB Escherichia coli ATCC 8739 cation transport regulator YP_001725367.1 2653259 R 481805 CDS YP_001725368.1 170020414 6066646 2653759..2654859 1 NC_010468.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ssn:SSON_1961 sodium-calcium/proton antiporter; calcium/sodium:proton antiporter 2654859 6066646 EcolC_2407 Escherichia coli ATCC 8739 calcium/sodium:proton antiporter YP_001725368.1 2653759 D 481805 CDS YP_001725369.1 170020415 6068705 2655237..2655371 1 NC_010468.1 KEGG: sfv:SFV_1231 hypothetical protein; hypothetical protein 2655371 6068705 EcolC_2408 Escherichia coli ATCC 8739 hypothetical protein YP_001725369.1 2655237 D 481805 CDS YP_001725370.1 170020416 6064532 2655772..2655906 1 NC_010468.1 KEGG: sbo:SBO_1851 hypothetical protein; hypothetical protein 2655906 6064532 EcolC_2409 Escherichia coli ATCC 8739 hypothetical protein YP_001725370.1 2655772 D 481805 CDS YP_001725371.1 170020417 6066635 2656307..2656441 1 NC_010468.1 KEGG: sbo:SBO_1851 hypothetical protein; hypothetical protein 2656441 6066635 EcolC_2410 Escherichia coli ATCC 8739 hypothetical protein YP_001725371.1 2656307 D 481805 CDS YP_001725372.1 170020418 6066544 complement(2656588..2657442) 1 NC_010468.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 2657442 6066544 EcolC_2411 Escherichia coli ATCC 8739 2-dehydro-3-deoxyphosphooctonate aldolase YP_001725372.1 2656588 R 481805 CDS YP_001725373.1 170020419 6066443 complement(2657478..2658287) 1 NC_010468.1 KEGG: sfv:SFV_1228 hypothetical protein; putative transcriptional regulator 2658287 6066443 EcolC_2412 Escherichia coli ATCC 8739 putative transcriptional regulator YP_001725373.1 2657478 R 481805 CDS YP_001725374.1 170020420 6066505 complement(2658291..2658683) 1 NC_010468.1 PFAM: Invasion gene expression up-regulator SirB; KEGG: sdy:SDY_1262 hypothetical protein; putative transcriptional regulator 2658683 6066505 EcolC_2413 Escherichia coli ATCC 8739 putative transcriptional regulator YP_001725374.1 2658291 R 481805 CDS YP_001725375.1 170020421 6066435 complement(2658680..2659513) 1 NC_010468.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2659513 6066435 EcolC_2414 Escherichia coli ATCC 8739 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001725375.1 2658680 R 481805 CDS YP_001725376.1 170020422 6066487 complement(2659513..2660595) 1 NC_010468.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2660595 prfA 6066487 prfA Escherichia coli ATCC 8739 peptide chain release factor 1 YP_001725376.1 2659513 R 481805 CDS YP_001725377.1 170020423 6068570 complement(2660637..2661893) 1 NC_010468.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 2661893 hemA 6068570 hemA Escherichia coli ATCC 8739 glutamyl-tRNA reductase YP_001725377.1 2660637 R 481805 CDS YP_001725378.1 170020424 6066427 2662107..2662730 1 NC_010468.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 2662730 lolB 6066427 lolB Escherichia coli ATCC 8739 outer membrane lipoprotein LolB YP_001725378.1 2662107 D 481805 CDS YP_001725379.1 170020425 6066426 2662730..2663581 1 NC_010468.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2663581 ipk 6066426 ipk Escherichia coli ATCC 8739 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001725379.1 2662730 D 481805 CDS YP_001725380.1 170020426 6066395 2663732..2664679 1 NC_010468.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2664679 6066395 EcolC_2419 Escherichia coli ATCC 8739 ribose-phosphate pyrophosphokinase YP_001725380.1 2663732 D 481805 CDS YP_001725381.1 170020427 6066168 2664831..2666483 1 NC_010468.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM 2666483 6066168 EcolC_2420 Escherichia coli ATCC 8739 putative sulfate transporter YchM YP_001725381.1 2664831 D 481805 CDS YP_001725382.1 170020428 6066172 complement(2666538..2666816) 1 NC_010468.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 2666816 6066172 EcolC_2421 Escherichia coli ATCC 8739 hypothetical protein YP_001725382.1 2666538 R 481805 CDS YP_001725383.1 170020429 6067084 2667094..2667678 1 NC_010468.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2667678 6067084 EcolC_2422 Escherichia coli ATCC 8739 peptidyl-tRNA hydrolase YP_001725383.1 2667094 D 481805 CDS YP_001725384.1 170020430 6068471 2667795..2668886 1 NC_010468.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2668886 6068471 EcolC_2423 Escherichia coli ATCC 8739 GTP-dependent nucleic acid-binding protein EngD YP_001725384.1 2667795 D 481805 CDS YP_001725385.1 170020431 6068472 2669655..2672522 1 NC_010468.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfx:S1289 putative adhesion and penetration protein; outer membrane autotransporter 2672522 6068472 EcolC_2424 Escherichia coli ATCC 8739 outer membrane autotransporter YP_001725385.1 2669655 D 481805 CDS YP_001725386.1 170020432 6066304 complement(2672622..2674541) 1 NC_010468.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 2674541 6066304 EcolC_2425 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator DhaR YP_001725386.1 2672622 R 481805 CDS YP_001725387.1 170020433 6066264 2674769..2675839 1 NC_010468.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 2675839 6066264 EcolC_2426 Escherichia coli ATCC 8739 dihydroxyacetone kinase subunit DhaK YP_001725387.1 2674769 D 481805 CDS YP_001725388.1 170020434 6068597 2675850..2676482 1 NC_010468.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 2676482 6068597 EcolC_2427 Escherichia coli ATCC 8739 dihydroxyacetone kinase subunit DhaL YP_001725388.1 2675850 D 481805 CDS YP_001725389.1 170020435 6064460 2676493..2677911 1 NC_010468.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM 2677911 6064460 EcolC_2428 Escherichia coli ATCC 8739 dihydroxyacetone kinase subunit DhaM YP_001725389.1 2676493 D 481805 CDS YP_001725390.1 170020436 6066275 2678231..2679928 1 NC_010468.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 2679928 treA 6066275 treA Escherichia coli ATCC 8739 trehalase YP_001725390.1 2678231 D 481805 CDS YP_001725391.1 170020437 6066281 complement(2680625..2680879) 1 NC_010468.1 PFAM: Transglycosylase-associated protein; KEGG: sdy:SDY_1234 hypothetical protein; transglycosylase-associated protein 2680879 6066281 EcolC_2430 Escherichia coli ATCC 8739 transglycosylase-associated protein YP_001725391.1 2680625 R 481805 CDS YP_001725392.1 170020438 6066367 2681080..2681814 1 NC_010468.1 PFAM: type IV pilus assembly PilZ; YcgR family protein; KEGG: sbo:SBO_1878 hypothetical protein; YcgR family protein 2681814 6066367 EcolC_2431 Escherichia coli ATCC 8739 YcgR family protein YP_001725392.1 2681080 D 481805 CDS YP_001725393.1 170020439 6065262 complement(2681816..2682427) 1 NC_010468.1 PFAM: Lytic transglycosylase catalytic; KEGG: ssn:SSON_1184 murein transglycosylase E; lytic transglycosylase 2682427 6065262 EcolC_2432 Escherichia coli ATCC 8739 lytic transglycosylase YP_001725393.1 2681816 R 481805 CDS YP_001725394.1 170020440 6064345 2682527..2683441 1 NC_010468.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 2683441 ldcA 6064345 ldcA Escherichia coli ATCC 8739 L,D-carboxypeptidase A YP_001725394.1 2682527 D 481805 CDS YP_001725395.1 170020441 6068426 2683536..2685272 1 NC_010468.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 2685272 6068426 EcolC_2434 Escherichia coli ATCC 8739 potassium/proton antiporter YP_001725395.1 2683536 D 481805 CDS YP_001725396.1 170020442 6066318 complement(2685658..2686728) 1 NC_010468.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 2686728 dadX 6066318 dadX Escherichia coli ATCC 8739 alanine racemase YP_001725396.1 2685658 R 481805 CDS YP_001725397.1 170020443 6065854 complement(2686738..2688036) 1 NC_010468.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 2688036 6065854 EcolC_2436 Escherichia coli ATCC 8739 D-amino acid dehydrogenase small subunit YP_001725397.1 2686738 R 481805 CDS YP_001725398.1 170020444 6068490 2688366..2689898 1 NC_010468.1 PFAM: SpoVR family protein; KEGG: ssn:SSON_1180 putative sporulation protein; SpoVR family protein 2689898 6068490 EcolC_2437 Escherichia coli ATCC 8739 SpoVR family protein YP_001725398.1 2688366 D 481805 CDS YP_001725399.1 170020445 6065842 complement(2689950..2690669) 1 NC_010468.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 2690669 6065842 EcolC_2438 Escherichia coli ATCC 8739 fatty acid metabolism regulator YP_001725399.1 2689950 R 481805 CDS YP_001725400.1 170020446 6068476 2690890..2692431 1 NC_010468.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 2692431 nhaB 6068476 nhaB Escherichia coli ATCC 8739 sodium/proton antiporter YP_001725400.1 2690890 D 481805 CDS YP_001725401.1 170020447 6066030 2692577..2693107 1 NC_010468.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 2693107 6066030 EcolC_2440 Escherichia coli ATCC 8739 disulfide bond formation protein B YP_001725401.1 2692577 D 481805 CDS YP_001725402.1 170020448 6066095 complement(2693153..2694421) 1 NC_010468.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 2694421 umuC 6066095 umuC Escherichia coli ATCC 8739 DNA polymerase V subunit UmuC YP_001725402.1 2693153 R 481805 CDS YP_001725403.1 170020449 6066101 complement(2694421..2694840) 1 NC_010468.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 2694840 6066101 EcolC_2442 Escherichia coli ATCC 8739 DNA polymerase V subunit UmuD YP_001725403.1 2694421 R 481805 CDS YP_001725404.1 170020450 6068292 complement(2696320..2696766) 1 NC_010468.1 PFAM: protein of unknown function UPF0153; KEGG: sfv:SFV_1188 hypothetical protein; hypothetical protein 2696766 6068292 EcolC_2444 Escherichia coli ATCC 8739 hypothetical protein YP_001725404.1 2696320 R 481805 CDS YP_001725405.1 170020451 6068409 complement(2696858..2697517) 1 NC_010468.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sbo:SBO_1166 putative isomerase; hypothetical protein 2697517 6068409 EcolC_2445 Escherichia coli ATCC 8739 hypothetical protein YP_001725405.1 2696858 R 481805 CDS YP_001725406.1 170020452 6068373 complement(2697589..2697882) 1 NC_010468.1 PFAM: protein of unknown function DUF709; KEGG: sbo:SBO_1165 hypothetical protein; hypothetical protein 2697882 6068373 EcolC_2446 Escherichia coli ATCC 8739 hypothetical protein YP_001725406.1 2697589 R 481805 CDS YP_001725407.1 170020453 6065973 2698124..2698525 1 NC_010468.1 PFAM: peptidase domain protein; KEGG: sdy:SDY_1210 hypothetical protein; peptidase domain-containing protein 2698525 6065973 EcolC_2447 Escherichia coli ATCC 8739 peptidase domain-containing protein YP_001725407.1 2698124 D 481805 CDS YP_001725408.1 170020454 6065993 complement(2698628..2698996) 1 NC_010468.1 PFAM: Fels-1 Propage domain protein; KEGG: ssn:SSON_1166 hypothetical protein; Fels-1 Propage domain-containing protein 2698996 6065993 EcolC_2448 Escherichia coli ATCC 8739 Fels-1 Propage domain-containing protein YP_001725408.1 2698628 R 481805 CDS YP_001725409.1 170020455 6066014 2699516..2700211 1 NC_010468.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 2700211 minC 6066014 minC Escherichia coli ATCC 8739 septum formation inhibitor YP_001725409.1 2699516 D 481805 CDS YP_001725410.1 170020456 6068258 2700235..2701047 1 NC_010468.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 2701047 6068258 EcolC_2450 Escherichia coli ATCC 8739 cell division inhibitor MinD YP_001725410.1 2700235 D 481805 CDS YP_001725411.1 170020457 6065873 2701051..2701317 1 NC_010468.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 2701317 minE 6065873 minE Escherichia coli ATCC 8739 cell division topological specificity factor MinE YP_001725411.1 2701051 D 481805 CDS YP_001725412.1 170020458 6068723 2702668..2702922 1 NC_010468.1 KEGG: sbo:SBO_1897 hypothetical protein; hypothetical protein 2702922 6068723 EcolC_2453 Escherichia coli ATCC 8739 hypothetical protein YP_001725412.1 2702668 D 481805 CDS YP_001725413.1 170020459 6067055 join(2702973..2703227,2703227..2703670) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 2703670 6067055 EcolC_2454 Escherichia coli ATCC 8739 insertion element protein YP_001725413.1 2702973 D 481805 CDS YP_001725414.1 170020460 6067054 2703739..2704068 1 NC_010468.1 KEGG: ssn:SSON_1161 hypothetical protein; hypothetical protein 2704068 6067054 EcolC_2455 Escherichia coli ATCC 8739 hypothetical protein YP_001725414.1 2703739 D 481805 CDS YP_001725415.1 170020461 6067043 complement(2707171..2707425) 1 NC_010468.1 hypothetical protein 2707425 6067043 EcolC_2457 Escherichia coli ATCC 8739 hypothetical protein YP_001725415.1 2707171 R 481805 CDS YP_001725416.1 170020462 6067030 complement(2707521..2709086) 1 NC_010468.1 PFAM: EAL domain protein; KEGG: sfx:S1241 hypothetical protein; diguanylate phosphodiesterase 2709086 6067030 EcolC_2458 Escherichia coli ATCC 8739 diguanylate phosphodiesterase YP_001725416.1 2707521 R 481805 CDS YP_001725417.1 170020463 6067027 complement(2709376..2709624) 1 NC_010468.1 hypothetical protein 2709624 6067027 EcolC_2459 Escherichia coli ATCC 8739 hypothetical protein YP_001725417.1 2709376 R 481805 CDS YP_001725418.1 170020464 6067023 complement(2709737..2710003) 1 NC_010468.1 KEGG: ent:Ent638_1754 hypothetical protein; hypothetical protein 2710003 6067023 EcolC_2460 Escherichia coli ATCC 8739 hypothetical protein YP_001725418.1 2709737 R 481805 CDS YP_001725419.1 170020465 6067017 complement(2710032..2710304) 1 NC_010468.1 hypothetical protein 2710304 6067017 EcolC_2461 Escherichia coli ATCC 8739 hypothetical protein YP_001725419.1 2710032 R 481805 CDS YP_001725420.1 170020466 6067013 complement(2710347..2710583) 1 NC_010468.1 KEGG: ent:Ent638_1756 hypothetical protein; hypothetical protein 2710583 6067013 EcolC_2462 Escherichia coli ATCC 8739 hypothetical protein YP_001725420.1 2710347 R 481805 CDS YP_001725421.1 170020467 6067005 2710897..2712108 1 NC_010468.1 PFAM: EAL domain protein; BLUF domain protein; KEGG: kpn:KPN_00782 hypothetical protein; diguanylate phosphodiesterase 2712108 6067005 EcolC_2463 Escherichia coli ATCC 8739 diguanylate phosphodiesterase YP_001725421.1 2710897 D 481805 CDS YP_001725422.1 170020468 6068672 2712313..2713044 1 NC_010468.1 PFAM: regulatory protein MerR; KEGG: ssn:SSON_1157 putative transcriptional regulator; MerR family transcriptional regulator 2713044 6068672 EcolC_2464 Escherichia coli ATCC 8739 MerR family transcriptional regulator YP_001725422.1 2712313 D 481805 CDS YP_001725423.1 170020469 6064587 2713265..2713669 1 NC_010468.1 PFAM: protein of unknown function DUF1398; KEGG: ssn:SSON_1156 hypothetical protein; hypothetical protein 2713669 6064587 EcolC_2465 Escherichia coli ATCC 8739 hypothetical protein YP_001725423.1 2713265 D 481805 CDS YP_001725424.1 170020470 6067425 2714369..2714692 1 NC_010468.1 KEGG: sdy:SDY_2015 hypothetical protein; hypothetical protein 2714692 6067425 EcolC_2466 Escherichia coli ATCC 8739 hypothetical protein YP_001725424.1 2714369 D 481805 CDS YP_001725425.1 170020471 6065921 complement(2714795..2716045) 1 NC_010468.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 2716045 6065921 EcolC_2467 Escherichia coli ATCC 8739 isocitrate dehydrogenase YP_001725425.1 2714795 R 481805 CDS YP_001725426.1 170020472 6067650 2716217..2716870 1 NC_010468.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 2716870 6067650 EcolC_2468 Escherichia coli ATCC 8739 23S rRNA pseudouridine synthase E YP_001725426.1 2716217 D 481805 CDS YP_001725427.1 170020473 6065026 2716880..2717341 1 NC_010468.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_2018 putative phosphohydrolase; NUDIX hydrolase 2717341 6065026 EcolC_2469 Escherichia coli ATCC 8739 NUDIX hydrolase YP_001725427.1 2716880 D 481805 CDS YP_001725428.1 170020474 6064998 2717395..2718501 1 NC_010468.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2718501 mnmA 6064998 mnmA Escherichia coli ATCC 8739 tRNA-specific 2-thiouridylase MnmA YP_001725428.1 2717395 D 481805 CDS YP_001725429.1 170020475 6064876 2718537..2719178 1 NC_010468.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 2719178 6064876 EcolC_2471 Escherichia coli ATCC 8739 hypothetical protein YP_001725429.1 2718537 D 481805 CDS YP_001725430.1 170020476 6064721 2719182..2720552 1 NC_010468.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 2720552 6064721 EcolC_2472 Escherichia coli ATCC 8739 adenylosuccinate lyase YP_001725430.1 2719182 D 481805 CDS YP_001725431.1 170020477 6067624 2720721..2721392 1 NC_010468.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 2721392 6067624 EcolC_2473 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator PhoP YP_001725431.1 2720721 D 481805 CDS YP_001725432.1 170020478 6067606 2721392..2722852 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: sbo:SBO_1910 sensor protein PhoQ; sensor protein PhoQ 2722852 6067606 EcolC_2474 Escherichia coli ATCC 8739 sensor protein PhoQ YP_001725432.1 2721392 D 481805 CDS YP_001725433.1 170020479 6067384 2722928..2724049 1 NC_010468.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: sbo:SBO_1911 hypothetical protein; cupin 4 family protein 2724049 6067384 EcolC_2475 Escherichia coli ATCC 8739 cupin 4 family protein YP_001725433.1 2722928 D 481805 CDS YP_001725434.1 170020480 6066875 complement(2724098..2725324) 1 NC_010468.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 2725324 6066875 EcolC_2476 Escherichia coli ATCC 8739 peptidase T YP_001725434.1 2724098 R 481805 CDS YP_001725435.1 170020481 6066749 2725574..2726710 1 NC_010468.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 2726710 potA 6066749 potA Escherichia coli ATCC 8739 putrescine/spermidine ABC transporter ATPase YP_001725435.1 2725574 D 481805 CDS YP_001725436.1 170020482 6066740 2726694..2727551 1 NC_010468.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 2727551 potB 6066740 potB Escherichia coli ATCC 8739 spermidine/putrescine ABC transporter membrane protein YP_001725436.1 2726694 D 481805 CDS YP_001725437.1 170020483 6066522 2727548..2728342 1 NC_010468.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 2728342 potC 6066522 potC Escherichia coli ATCC 8739 spermidine/putrescine ABC transporter membrane protein YP_001725437.1 2727548 D 481805 CDS YP_001725438.1 170020484 6066170 2728339..2729385 1 NC_010468.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 2729385 potD 6066170 potD Escherichia coli ATCC 8739 spermidine/putrescine ABC transporter substrate-binding protein YP_001725438.1 2728339 D 481805 CDS YP_001725439.1 170020485 6065722 complement(2729522..2730361) 1 NC_010468.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 2730361 6065722 EcolC_2481 Escherichia coli ATCC 8739 NAD-dependent deacetylase YP_001725439.1 2729522 R 481805 CDS YP_001725440.1 170020486 6065563 complement(2730377..2731288) 1 NC_010468.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 2731288 6065563 EcolC_2482 Escherichia coli ATCC 8739 N-acetyl-D-glucosamine kinase YP_001725440.1 2730377 R 481805 CDS YP_001725441.1 170020487 6065438 complement(2731317..2732555) 1 NC_010468.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 2732555 6065438 EcolC_2483 Escherichia coli ATCC 8739 outer membrane-specific lipoprotein transporter subunit LolE YP_001725441.1 2731317 R 481805 CDS YP_001725442.1 170020488 6065274 complement(2732561..2733262) 1 NC_010468.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 2733262 lolD 6065274 lolD Escherichia coli ATCC 8739 lipoprotein transporter ATP-binding subunit YP_001725442.1 2732561 R 481805 CDS YP_001725443.1 170020489 6065254 complement(2733255..2734454) 1 NC_010468.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 2734454 6065254 EcolC_2485 Escherichia coli ATCC 8739 outer membrane-specific lipoprotein transporter subunit LolC YP_001725443.1 2733255 R 481805 CDS YP_001725444.1 170020490 6065817 2734716..2735789 1 NC_010468.1 PFAM: acyltransferase 3; KEGG: ssn:SSON_1135 hypothetical protein; acyltransferase 3 2735789 6065817 EcolC_2486 Escherichia coli ATCC 8739 acyltransferase 3 YP_001725444.1 2734716 D 481805 CDS YP_001725445.1 170020491 6065208 2735869..2739363 1 NC_010468.1 KEGG: sfv:SFV_1134 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; transcription-repair coupling factor 2739363 6065208 EcolC_2487 Escherichia coli ATCC 8739 transcription-repair coupling factor YP_001725445.1 2735869 D 481805 CDS YP_001725446.1 170020492 6065172 2739510..2740469 1 NC_010468.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2037 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 2740469 6065172 EcolC_2488 Escherichia coli ATCC 8739 ErfK/YbiS/YcfS/YnhG family protein YP_001725446.1 2739510 D 481805 CDS YP_001725447.1 170020493 6064894 complement(2740552..2740809) 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: sdy:SDY_2038 hypothetical protein; hypothetical protein 2740809 6064894 EcolC_2489 Escherichia coli ATCC 8739 hypothetical protein YP_001725447.1 2740552 R 481805 CDS YP_001725448.1 170020494 6064862 2741050..2741682 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: sdy:SDY_2039 hypothetical protein; TetR family transcriptional regulator 2741682 6064862 EcolC_2490 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001725448.1 2741050 D 481805 CDS YP_001725449.1 170020495 6064754 complement(2741744..2742283) 1 NC_010468.1 PFAM: 17 kDa surface antigen; KEGG: sdy:SDY_2040 hypothetical protein; hypothetical protein 2742283 6064754 EcolC_2491 Escherichia coli ATCC 8739 hypothetical protein YP_001725449.1 2741744 R 481805 CDS YP_001725450.1 170020496 6066509 complement(2742510..2743814) 1 NC_010468.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sfx:S1193 respiratory NADH dehydrogenase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2743814 6066509 EcolC_2492 Escherichia coli ATCC 8739 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_001725450.1 2742510 R 481805 CDS YP_001725451.1 170020497 6065666 complement(2744222..2744764) 1 NC_010468.1 PFAM: protein of unknown function UPF0227; KEGG: sdy:SDY_2042 hypothetical protein; hypothetical protein 2744764 6065666 EcolC_2493 Escherichia coli ATCC 8739 hypothetical protein YP_001725451.1 2744222 R 481805 CDS YP_001725452.1 170020498 6067647 complement(2744787..2745812) 1 NC_010468.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 2745812 6067647 EcolC_2494 Escherichia coli ATCC 8739 beta-hexosaminidase YP_001725452.1 2744787 R 481805 CDS YP_001725453.1 170020499 6067178 complement(2745823..2746647) 1 NC_010468.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 2746647 thiK 6067178 thiK Escherichia coli ATCC 8739 thiamine kinase YP_001725453.1 2745823 R 481805 CDS YP_001725454.1 170020500 6067150 complement(2746628..2747269) 1 NC_010468.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: sdy:SDY_2045 hypothetical protein; membrane lipoprotein lipid attachment site 2747269 6067150 EcolC_2496 Escherichia coli ATCC 8739 membrane lipoprotein lipid attachment site YP_001725454.1 2746628 R 481805 CDS YP_001725455.1 170020501 6066739 complement(2747283..2747660) 1 NC_010468.1 PFAM: protein of unknown function DUF1425; KEGG: sdy:SDY_2046 hypothetical protein; hypothetical protein 2747660 6066739 EcolC_2497 Escherichia coli ATCC 8739 hypothetical protein YP_001725455.1 2747283 R 481805 CDS YP_001725456.1 170020502 6065914 complement(2747663..2748022) 1 NC_010468.1 PFAM: histidine triad (HIT) protein; KEGG: sdy:SDY_2047 hypothetical protein; purine nucleoside phosphoramidase 2748022 6065914 EcolC_2498 Escherichia coli ATCC 8739 purine nucleoside phosphoramidase YP_001725456.1 2747663 R 481805 CDS YP_001725457.1 170020503 6065845 2748356..2750545 1 NC_010468.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sdy:SDY_2048 outer membrane receptor for ferric iron uptake; ferric-rhodotorulic acid outer membrane transporter 2750545 6065845 EcolC_2499 Escherichia coli ATCC 8739 ferric-rhodotorulic acid outer membrane transporter YP_001725457.1 2748356 D 481805 CDS YP_001725458.1 170020504 6066847 complement(2750605..2752038) 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 2752038 6066847 EcolC_2500 Escherichia coli ATCC 8739 PTS system glucose-specific transporter subunit IIBC YP_001725458.1 2750605 R 481805 CDS YP_001725459.1 170020505 6067376 complement(2752333..2753130) 1 NC_010468.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: sdy:SDY_2050 hypothetical protein; putative metallodependent hydrolase 2753130 6067376 EcolC_2501 Escherichia coli ATCC 8739 putative metallodependent hydrolase YP_001725459.1 2752333 R 481805 CDS YP_001725460.1 170020506 6065974 complement(2753141..2754145) 1 NC_010468.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 2754145 6065974 EcolC_2502 Escherichia coli ATCC 8739 DNA polymerase III subunit delta' YP_001725460.1 2753141 R 481805 CDS YP_001725461.1 170020507 6066038 complement(2754142..2754783) 1 NC_010468.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 2754783 tmk 6066038 tmk Escherichia coli ATCC 8739 thymidylate kinase YP_001725461.1 2754142 R 481805 CDS YP_001725462.1 170020508 6066341 complement(2754773..2755795) 1 NC_010468.1 PFAM: aminodeoxychorismate lyase; KEGG: sbo:SBO_1966 putative thymidylate kinase; hypothetical protein 2755795 6066341 EcolC_2504 Escherichia coli ATCC 8739 hypothetical protein YP_001725462.1 2754773 R 481805 CDS YP_001725463.1 170020509 6065127 complement(2755798..2756607) 1 NC_010468.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 2756607 6065127 EcolC_2505 Escherichia coli ATCC 8739 4-amino-4-deoxychorismate lyase YP_001725463.1 2755798 R 481805 CDS YP_001725464.1 170020510 6066138 complement(2756727..2757968) 1 NC_010468.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 2757968 6066138 EcolC_2506 Escherichia coli ATCC 8739 3-oxoacyl-(acyl carrier protein) synthase II YP_001725464.1 2756727 R 481805 CDS YP_001725465.1 170020511 6066350 complement(2758056..2758292) 1 NC_010468.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 2758292 acpP 6066350 acpP Escherichia coli ATCC 8739 acyl carrier protein YP_001725465.1 2758056 R 481805 CDS YP_001725466.1 170020512 6066387 complement(2758503..2759237) 1 NC_010468.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2759237 fabG 6066387 fabG Escherichia coli ATCC 8739 3-ketoacyl-ACP reductase YP_001725466.1 2758503 R 481805 CDS YP_001725467.1 170020513 6066647 complement(2759250..2760179) 1 NC_010468.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: sfv:SFV_1112 malonyl-CoA-[acyl-carrier-protein] transacylase; malonyl CoA-acyl carrier protein transacylase 2760179 6066647 EcolC_2509 Escherichia coli ATCC 8739 malonyl CoA-acyl carrier protein transacylase YP_001725467.1 2759250 R 481805 CDS YP_001725468.1 170020514 6066849 complement(2760195..2761148) 1 NC_010468.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 2761148 6066849 EcolC_2510 Escherichia coli ATCC 8739 3-oxoacyl-ACP synthase YP_001725468.1 2760195 R 481805 CDS YP_001725469.1 170020515 6066778 complement(2761216..2762286) 1 NC_010468.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 2762286 6066778 EcolC_2511 Escherichia coli ATCC 8739 putative glycerol-3-phosphate acyltransferase PlsX YP_001725469.1 2761216 R 481805 CDS YP_001725470.1 170020516 6066818 complement(2762367..2762540) 1 NC_010468.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2762540 rpmF 6066818 rpmF Escherichia coli ATCC 8739 50S ribosomal protein L32 YP_001725470.1 2762367 R 481805 CDS YP_001725471.1 170020517 6066890 complement(2762592..2763113) 1 NC_010468.1 PFAM: protein of unknown function DUF177; KEGG: sbo:SBO_1975 hypothetical protein; hypothetical protein 2763113 6066890 EcolC_2513 Escherichia coli ATCC 8739 hypothetical protein YP_001725471.1 2762592 R 481805 CDS YP_001725472.1 170020518 6066880 2763273..2763896 1 NC_010468.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 2763896 6066880 EcolC_2514 Escherichia coli ATCC 8739 Maf-like protein YP_001725472.1 2763273 D 481805 CDS YP_001725473.1 170020519 6067180 complement(2764008..2764967) 1 NC_010468.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 2764967 6067180 EcolC_2515 Escherichia coli ATCC 8739 23S rRNA pseudouridylate synthase C YP_001725473.1 2764008 R 481805 CDS YP_001725474.1 170020520 6067377 2765540..2768725 1 NC_010468.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 2768725 rne 6067377 rne Escherichia coli ATCC 8739 ribonuclease E YP_001725474.1 2765540 D 481805 CDS YP_001725475.1 170020521 6067369 complement(2768922..2769875) 1 NC_010468.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 2769875 flgL 6067369 flgL Escherichia coli ATCC 8739 flagellar hook-associated protein FlgL YP_001725475.1 2768922 R 481805 CDS YP_001725476.1 170020522 6067378 complement(2769887..2771530) 1 NC_010468.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 2771530 flgK 6067378 flgK Escherichia coli ATCC 8739 flagellar hook-associated protein FlgK YP_001725476.1 2769887 R 481805 CDS YP_001725477.1 170020523 6067379 complement(2771596..2772537) 1 NC_010468.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 2772537 flgJ 6067379 flgJ Escherichia coli ATCC 8739 flagellar rod assembly protein/muramidase FlgJ YP_001725477.1 2771596 R 481805 CDS YP_001725478.1 170020524 6067381 complement(2772537..2773634) 1 NC_010468.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 2773634 flgI 6067381 flgI Escherichia coli ATCC 8739 flagellar basal body P-ring protein YP_001725478.1 2772537 R 481805 CDS YP_001725479.1 170020525 6067419 complement(2773646..2774353) 1 NC_010468.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 2774353 flgH 6067419 flgH Escherichia coli ATCC 8739 flagellar basal body L-ring protein YP_001725479.1 2773646 R 481805 CDS YP_001725480.1 170020526 6067435 complement(2774397..2775179) 1 NC_010468.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 2775179 flgG 6067435 flgG Escherichia coli ATCC 8739 flagellar basal body rod protein FlgG YP_001725480.1 2774397 R 481805 CDS YP_001725481.1 170020527 6067421 complement(2775351..2776106) 1 NC_010468.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 2776106 flgF 6067421 flgF Escherichia coli ATCC 8739 flagellar basal body rod protein FlgF YP_001725481.1 2775351 R 481805 CDS YP_001725482.1 170020528 6067440 complement(2776126..2777334) 1 NC_010468.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 2777334 flgE 6067440 flgE Escherichia coli ATCC 8739 flagellar hook protein FlgE YP_001725482.1 2776126 R 481805 CDS YP_001725483.1 170020529 6067473 complement(2777359..2778054) 1 NC_010468.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 2778054 flgD 6067473 flgD Escherichia coli ATCC 8739 flagellar basal body rod modification protein YP_001725483.1 2777359 R 481805 CDS YP_001725484.1 170020530 6067228 complement(2778066..2778470) 1 NC_010468.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 2778470 flgC 6067228 flgC Escherichia coli ATCC 8739 flagellar basal body rod protein FlgC YP_001725484.1 2778066 R 481805 CDS YP_001725485.1 170020531 6067476 complement(2778474..2778890) 1 NC_010468.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 2778890 flgB 6067476 flgB Escherichia coli ATCC 8739 flagellar basal body rod protein FlgB YP_001725485.1 2778474 R 481805 CDS YP_001725486.1 170020532 6067483 2779046..2779705 1 NC_010468.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 2779705 flgA 6067483 flgA Escherichia coli ATCC 8739 flagellar basal body P-ring biosynthesis protein FlgA YP_001725486.1 2779046 D 481805 CDS YP_001725487.1 170020533 6067480 2779781..2780074 1 NC_010468.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 2780074 6067480 EcolC_2529 Escherichia coli ATCC 8739 anti-sigma-28 factor FlgM YP_001725487.1 2779781 D 481805 CDS YP_001725488.1 170020534 6067489 2780079..2780495 1 NC_010468.1 PFAM: FlgN family protein; KEGG: ssn:SSON_1090 protein of flagellar biosynthesis; FlgN family protein 2780495 6067489 EcolC_2530 Escherichia coli ATCC 8739 FlgN family protein YP_001725488.1 2780079 D 481805 CDS YP_001725489.1 170020535 6067486 complement(2780535..2782070) 1 NC_010468.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: sbo:SBO_1995 putative virulence factor; integral membrane protein MviN 2782070 6067486 EcolC_2531 Escherichia coli ATCC 8739 integral membrane protein MviN YP_001725489.1 2780535 R 481805 CDS YP_001725490.1 170020536 6067514 complement(2782180..2783103) 1 NC_010468.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sdy:SDY_2084 putative virulence factor; oxidoreductase domain-containing protein 2783103 6067514 EcolC_2532 Escherichia coli ATCC 8739 oxidoreductase domain-containing protein YP_001725490.1 2782180 R 481805 CDS YP_001725491.1 170020537 6067576 complement(2783105..2783752) 1 NC_010468.1 PFAM: protein of unknown function DUF480; KEGG: ssn:SSON_1087 hypothetical protein; hypothetical protein 2783752 6067576 EcolC_2533 Escherichia coli ATCC 8739 hypothetical protein YP_001725491.1 2783105 R 481805 CDS YP_001725492.1 170020538 6067603 complement(2783763..2784347) 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_1998 RimJ; ribosomal-protein-S5-alanine N-acetyltransferase 2784347 6067603 EcolC_2534 Escherichia coli ATCC 8739 ribosomal-protein-S5-alanine N-acetyltransferase YP_001725492.1 2783763 R 481805 CDS YP_001725493.1 170020539 6067582 2784583..2785791 1 NC_010468.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 2785791 6067582 EcolC_2535 Escherichia coli ATCC 8739 multidrug resistance protein MdtH YP_001725493.1 2784583 D 481805 CDS YP_001725494.1 170020540 6067635 2785855..2786502 1 NC_010468.1 cofactor involved in the reduction of disulfides; glutaredoxin 2786502 6067635 EcolC_2536 Escherichia coli ATCC 8739 glutaredoxin YP_001725494.1 2785855 D 481805 CDS YP_001725495.1 170020541 6067268 2786636..2787196 1 NC_010468.1 PFAM: protein of unknown function DUF1439; KEGG: sbo:SBO_2001 hypothetical protein; hypothetical protein 2787196 6067268 EcolC_2537 Escherichia coli ATCC 8739 hypothetical protein YP_001725495.1 2786636 D 481805 CDS YP_001725496.1 170020542 6066465 2787302..2788348 1 NC_010468.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 2788348 6066465 EcolC_2538 Escherichia coli ATCC 8739 dihydroorotase YP_001725496.1 2787302 D 481805 CDS YP_001725497.1 170020543 6066285 2788422..2788667 1 NC_010468.1 PFAM: DinI family protein; KEGG: ssn:SSON_1081 damage-inducible protein I; DNA damage-inducible protein I 2788667 6066285 EcolC_2539 Escherichia coli ATCC 8739 DNA damage-inducible protein I YP_001725497.1 2788422 D 481805 CDS YP_001725498.1 170020544 6064997 2788957..2789211 1 NC_010468.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 2789211 bssS 6064997 bssS Escherichia coli ATCC 8739 biofilm formation regulatory protein BssS YP_001725498.1 2788957 D 481805 CDS YP_001725499.1 170020545 6065286 2789326..2790444 1 NC_010468.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 2790444 solA 6065286 solA Escherichia coli ATCC 8739 N-methyltryptophan oxidase YP_001725499.1 2789326 D 481805 CDS YP_001725500.1 170020546 6064931 2790492..2790605 1 NC_010468.1 KEGG: sdy:SDY_2097 hypothetical protein; hypothetical protein 2790605 6064931 EcolC_2542 Escherichia coli ATCC 8739 hypothetical protein YP_001725500.1 2790492 D 481805 CDS YP_001725501.1 170020547 6066801 2790866..2791432 1 NC_010468.1 PFAM: cytochrome B561; KEGG: ssn:SSON_1077 putative cytochrome; cytochrome B561 2791432 6066801 EcolC_2543 Escherichia coli ATCC 8739 cytochrome B561 YP_001725501.1 2790866 D 481805 CDS YP_001725502.1 170020548 6065397 2791436..2792011 1 NC_010468.1 PFAM: YceI family protein; KEGG: sbo:SBO_2008 hypothetical protein; hypothetical protein 2792011 6065397 EcolC_2544 Escherichia coli ATCC 8739 hypothetical protein YP_001725502.1 2791436 D 481805 CDS YP_001725503.1 170020549 6066165 complement(2792053..2793105) 1 NC_010468.1 PFAM: Rhodanese domain protein; KEGG: sfv:SFV_1078 hypothetical protein; hypothetical protein 2793105 6066165 EcolC_2545 Escherichia coli ATCC 8739 hypothetical protein YP_001725503.1 2792053 R 481805 CDS YP_001725504.1 170020550 6066529 2793330..2794250 1 NC_010468.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2794250 6066529 EcolC_2546 Escherichia coli ATCC 8739 lipid A biosynthesis lauroyl acyltransferase YP_001725504.1 2793330 D 481805 CDS YP_001725505.1 170020551 6066277 2794422..2795648 1 NC_010468.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 2795648 6066277 EcolC_2547 Escherichia coli ATCC 8739 drug efflux system protein MdtG YP_001725505.1 2794422 D 481805 CDS YP_001725506.1 170020552 6066526 2795731..2796105 1 NC_010468.1 KEGG: sdy:SDY_2299 acidic protein; hypothetical protein 2796105 6066526 EcolC_2548 Escherichia coli ATCC 8739 hypothetical protein YP_001725506.1 2795731 D 481805 CDS YP_001725507.1 170020553 6066636 complement(2796106..2796333) 1 NC_010468.1 PFAM: protein of unknown function DUF1375; KEGG: sdy:SDY_2300 hypothetical protein; hypothetical protein 2796333 6066636 EcolC_2549 Escherichia coli ATCC 8739 hypothetical protein YP_001725507.1 2796106 R 481805 CDS YP_001725508.1 170020554 6067328 complement(2796506..2799049) 1 NC_010468.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 2799049 6067328 EcolC_2550 Escherichia coli ATCC 8739 glucosyltransferase MdoH YP_001725508.1 2796506 R 481805 CDS YP_001725509.1 170020555 6067535 complement(2799042..2800577) 1 NC_010468.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 2800577 mdoG 6067535 mdoG Escherichia coli ATCC 8739 glucan biosynthesis protein G YP_001725509.1 2799042 R 481805 CDS YP_001725510.1 170020556 6067447 2800971..2802128 1 NC_010468.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 2802128 mdoC 6067447 mdoC Escherichia coli ATCC 8739 glucans biosynthesis protein YP_001725510.1 2800971 D 481805 CDS YP_001725511.1 170020557 6067628 complement(2802136..2803566) 1 NC_010468.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: sfx:S1116 putative synthase; phospholipase D/transphosphatidylase 2803566 6067628 EcolC_2553 Escherichia coli ATCC 8739 phospholipase D/transphosphatidylase YP_001725511.1 2802136 R 481805 CDS YP_001725512.1 170020558 6067555 complement(2803559..2804092) 1 NC_010468.1 PFAM: Appr-1-p processing domain protein; KEGG: sbo:SBO_2021 putative polyprotein; hypothetical protein 2804092 6067555 EcolC_2554 Escherichia coli ATCC 8739 hypothetical protein YP_001725512.1 2803559 R 481805 CDS YP_001725513.1 170020559 6066894 complement(2804187..2804498) 1 NC_010468.1 KEGG: ssn:SSON_1057 hypothetical protein; hypothetical protein 2804498 6066894 EcolC_2555 Escherichia coli ATCC 8739 hypothetical protein YP_001725513.1 2804187 R 481805 CDS YP_001725514.1 170020560 6066754 complement(2804619..2804951) 1 NC_010468.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 2804951 csgC 6066754 csgC Escherichia coli ATCC 8739 putative autoagglutination protein YP_001725514.1 2804619 R 481805 CDS YP_001725515.1 170020561 6064645 complement(2805010..2805465) 1 NC_010468.1 KEGG: sbo:SBO_2026 CsgA; cryptic curlin major subunit 2805465 6064645 EcolC_2557 Escherichia coli ATCC 8739 cryptic curlin major subunit YP_001725515.1 2805010 R 481805 CDS YP_001725516.1 170020562 6064775 complement(2805506..2805961) 1 NC_010468.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 2805961 6064775 EcolC_2558 Escherichia coli ATCC 8739 curlin minor subunit YP_001725516.1 2805506 R 481805 CDS YP_001725517.1 170020563 6064749 2806716..2807366 1 NC_010468.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 2807366 6064749 EcolC_2559 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator CsgD YP_001725517.1 2806716 D 481805 CDS YP_001725518.1 170020564 6064753 2807371..2807760 1 NC_010468.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 2807760 6064753 EcolC_2560 Escherichia coli ATCC 8739 curli assembly protein CsgE YP_001725518.1 2807371 D 481805 CDS YP_001725519.1 170020565 6064746 2807785..2808201 1 NC_010468.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 2808201 6064746 EcolC_2561 Escherichia coli ATCC 8739 curli assembly protein CsgF YP_001725519.1 2807785 D 481805 CDS YP_001725520.1 170020566 6064810 2808228..2809061 1 NC_010468.1 PFAM: Curli production assembly/transport component CsgG; KEGG: ssn:SSON_1046 curli production assembly/transport component, 2nd curli operon; curli production assembly/transport component CsgG 2809061 6064810 EcolC_2562 Escherichia coli ATCC 8739 curli production assembly/transport component CsgG YP_001725520.1 2808228 D 481805 CDS YP_001725521.1 170020567 6066661 complement(2809125..2809646) 1 NC_010468.1 PFAM: protein of unknown function DUF1097; KEGG: sbo:SBO_2032 hypothetical protein; hypothetical protein 2809646 6066661 EcolC_2563 Escherichia coli ATCC 8739 hypothetical protein YP_001725521.1 2809125 R 481805 CDS YP_001725522.1 170020568 6065707 complement(2809718..2810272) 1 NC_010468.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfv:SFV_1046 putative oxidoreductase component; cytoplasmic chaperone TorD family protein 2810272 6065707 EcolC_2564 Escherichia coli ATCC 8739 cytoplasmic chaperone TorD family protein YP_001725522.1 2809718 R 481805 CDS YP_001725523.1 170020569 6065797 complement(2810296..2811033) 1 NC_010468.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sbo:SBO_2034 hypothetical protein; putative hydrolase 2811033 6065797 EcolC_2565 Escherichia coli ATCC 8739 putative hydrolase YP_001725523.1 2810296 R 481805 CDS YP_001725524.1 170020570 6065906 complement(2811088..2812026) 1 NC_010468.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1042 putative dehydrogenase; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 2812026 6065906 EcolC_2566 Escherichia coli ATCC 8739 NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase YP_001725524.1 2811088 R 481805 CDS YP_001725525.1 170020571 6065163 complement(2812902..2813888) 1 NC_010468.1 KEGG: sfv:SFV_1042 hypothetical protein; hypothetical protein 2813888 6065163 EcolC_2567 Escherichia coli ATCC 8739 hypothetical protein YP_001725525.1 2812902 R 481805 CDS YP_001725526.1 170020572 6065047 complement(2813885..2814208) 1 NC_010468.1 KEGG: sfv:SFV_1041 hypothetical protein; hypothetical protein 2814208 6065047 EcolC_2568 Escherichia coli ATCC 8739 hypothetical protein YP_001725526.1 2813885 R 481805 CDS YP_001725527.1 170020573 6065058 2814294..2814593 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 2814593 6065058 EcolC_2569 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001725527.1 2814294 D 481805 CDS YP_001725528.1 170020574 6065037 2814590..2815456 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 2815456 6065037 EcolC_2570 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001725528.1 2814590 D 481805 CDS YP_001725529.1 170020575 6065004 complement(2815497..2816855) 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1377 hypothetical protein; diguanylate cyclase 2816855 6065004 EcolC_2571 Escherichia coli ATCC 8739 diguanylate cyclase YP_001725529.1 2815497 R 481805 CDS YP_001725530.1 170020576 6065019 2817442..2819865 1 NC_010468.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 2819865 pgaA 6065019 pgaA Escherichia coli ATCC 8739 outer membrane protein PgaA YP_001725530.1 2817442 D 481805 CDS YP_001725531.1 170020577 6064986 2819874..2821892 1 NC_010468.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 2821892 pgaB 6064986 pgaB Escherichia coli ATCC 8739 outer membrane N-deacetylase YP_001725531.1 2819874 D 481805 CDS YP_001725532.1 170020578 6065010 2821972..2823210 1 NC_010468.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2823210 6065010 EcolC_2574 Escherichia coli ATCC 8739 N-glycosyltransferase YP_001725532.1 2821972 D 481805 CDS YP_001725533.1 170020579 6064957 2823212..2823625 1 NC_010468.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; putative PGA biosynthesis protein 2823625 pgaD 6064957 pgaD Escherichia coli ATCC 8739 putative PGA biosynthesis protein YP_001725533.1 2823212 D 481805 CDS YP_001725534.1 170020580 6064930 complement(2823675..2824739) 1 NC_010468.1 PFAM: PhoH family protein; KEGG: sbo:SBO_2038 PhoB-dependent, ATP-binding pho regulon component; hypothetical protein 2824739 6064930 EcolC_2576 Escherichia coli ATCC 8739 hypothetical protein YP_001725534.1 2823675 R 481805 CDS YP_001725535.1 170020581 6064360 complement(2825084..2826355) 1 NC_010468.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbo:SBO_2039 hypothetical protein; Dyp-type peroxidase family protein 2826355 6064360 EcolC_2577 Escherichia coli ATCC 8739 Dyp-type peroxidase family protein YP_001725535.1 2825084 R 481805 CDS YP_001725536.1 170020582 6067275 complement(2826361..2827488) 1 NC_010468.1 KEGG: ssn:SSON_1037 hypothetical protein; hypothetical protein 2827488 6067275 EcolC_2578 Escherichia coli ATCC 8739 hypothetical protein YP_001725536.1 2826361 R 481805 CDS YP_001725537.1 170020583 6066602 complement(2827546..2828376) 1 NC_010468.1 TIGRFAM: FTR1 family protein; PFAM: iron permease FTR1; KEGG: ssn:SSON_1036 high-affinity iron permease; FTR1 family protein 2828376 6066602 EcolC_2579 Escherichia coli ATCC 8739 FTR1 family protein YP_001725537.1 2827546 R 481805 CDS YP_001725538.1 170020584 6067279 complement(2828918..2830426) 1 NC_010468.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: sbo:SBO_2042 major sodium/proline symporter; sodium/proline symporter 2830426 6067279 EcolC_2580 Escherichia coli ATCC 8739 sodium/proline symporter YP_001725538.1 2828918 R 481805 CDS YP_001725539.1 170020585 6066504 2830849..2834811 1 NC_010468.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 2834811 putA 6066504 putA Escherichia coli ATCC 8739 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_001725539.1 2830849 D 481805 CDS YP_001725540.1 170020586 6064884 complement(2834851..2835489) 1 NC_010468.1 PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YcdC domain protein; KEGG: sfv:SFV_1025 putative tet operon regulator; TetR family transcriptional regulator 2835489 6064884 EcolC_2582 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001725540.1 2834851 R 481805 CDS YP_001725541.1 170020587 6065458 2835778..2836869 1 NC_010468.1 PFAM: luciferase family protein; KEGG: sfv:SFV_1024 hypothetical protein; luciferase family protein 2836869 6065458 EcolC_2583 Escherichia coli ATCC 8739 luciferase family protein YP_001725541.1 2835778 D 481805 CDS YP_001725542.1 170020588 6064818 2836866..2837561 1 NC_010468.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1030 putative synthetase; isochorismatase hydrolase 2837561 6064818 EcolC_2584 Escherichia coli ATCC 8739 isochorismatase hydrolase YP_001725542.1 2836866 D 481805 CDS YP_001725543.1 170020589 6066796 2837573..2837959 1 NC_010468.1 PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_0985 hypothetical protein; endoribonuclease L-PSP 2837959 6066796 EcolC_2585 Escherichia coli ATCC 8739 endoribonuclease L-PSP YP_001725543.1 2837573 D 481805 CDS YP_001725544.1 170020590 6067530 2837967..2838767 1 NC_010468.1 PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_1027 putative acetyltransferase; alpha/beta hydrolase fold protein 2838767 6067530 EcolC_2586 Escherichia coli ATCC 8739 alpha/beta hydrolase fold protein YP_001725544.1 2837967 D 481805 CDS YP_001725545.1 170020591 6066638 2838777..2839367 1 NC_010468.1 PFAM: nitroreductase; KEGG: sfv:SFV_1020 putative enzyme; hypothetical protein 2839367 6066638 EcolC_2587 Escherichia coli ATCC 8739 hypothetical protein YP_001725545.1 2838777 D 481805 CDS YP_001725546.1 170020592 6067254 2839378..2839872 1 NC_010468.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sfv:SFV_1019 hypothetical protein; flavin reductase domain-containing protein 2839872 6067254 EcolC_2588 Escherichia coli ATCC 8739 flavin reductase domain-containing protein YP_001725546.1 2839378 D 481805 CDS YP_001725547.1 170020593 6067194 2839893..2841221 1 NC_010468.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_1024 putative transport protein; uracil-xanthine permease 2841221 6067194 EcolC_2589 Escherichia coli ATCC 8739 uracil-xanthine permease YP_001725547.1 2839893 D 481805 CDS YP_001725548.1 170020594 6065635 complement(2841479..2841652) 1 NC_010468.1 KEGG: cko:CKO_02046 hypothetical protein; hypothetical protein 2841652 6065635 EcolC_2590 Escherichia coli ATCC 8739 hypothetical protein YP_001725548.1 2841479 R 481805 CDS YP_001725549.1 170020595 6067454 2842025..2842621 1 NC_010468.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 2842621 6067454 EcolC_2591 Escherichia coli ATCC 8739 TrpR binding protein WrbA YP_001725549.1 2842025 D 481805 CDS YP_001725550.1 170020596 6065494 2842642..2842869 1 NC_010468.1 KEGG: sdy:SDY_0979 hypothetical protein; hypothetical protein 2842869 6065494 EcolC_2592 Escherichia coli ATCC 8739 hypothetical protein YP_001725550.1 2842642 D 481805 CDS YP_001725551.1 170020597 6066637 complement(2843089..2844330) 1 NC_010468.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 periplasmic glucose-1-phosphatase; glucose-1-phosphatase/inositol phosphatase 2844330 6066637 EcolC_2593 Escherichia coli ATCC 8739 glucose-1-phosphatase/inositol phosphatase YP_001725551.1 2843089 R 481805 CDS YP_001725552.1 170020598 6064540 complement(2844623..2845879) 1 NC_010468.1 KEGG: sfv:SFV_1013 hypothetical protein; hypothetical protein 2845879 6064540 EcolC_2594 Escherichia coli ATCC 8739 hypothetical protein YP_001725552.1 2844623 R 481805 CDS YP_001725553.1 170020599 6065284 2846140..2847060 1 NC_010468.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 2847060 6065284 EcolC_2595 Escherichia coli ATCC 8739 curved DNA-binding protein CbpA YP_001725553.1 2846140 D 481805 CDS YP_001725554.1 170020600 6067629 2847060..2847365 1 NC_010468.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 2847365 6067629 EcolC_2596 Escherichia coli ATCC 8739 chaperone-modulator protein CbpM YP_001725554.1 2847060 D 481805 CDS YP_001725555.1 170020601 6067080 complement(2847517..2848116) 1 NC_010468.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 2848116 torD 6067080 torD Escherichia coli ATCC 8739 chaperone protein TorD YP_001725555.1 2847517 R 481805 CDS YP_001725556.1 170020602 6066224 complement(2848113..2850659) 1 NC_010468.1 KEGG: sfv:SFV_1007 trimethylamine N-oxide reductase subunit; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin guanine dinucleotide-containing S/N-oxide reductase 2850659 6066224 EcolC_2598 Escherichia coli ATCC 8739 molybdopterin guanine dinucleotide-containing S/N-oxide reductase YP_001725556.1 2848113 R 481805 CDS YP_001725557.1 170020603 6064659 complement(2850659..2851831) 1 NC_010468.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: ssn:SSON_1004 trimethylamine N-oxide reductase, cytochrome c-type subunit; trimethylamine-N-oxide reductase c-type cytochrome TorC 2851831 6064659 EcolC_2599 Escherichia coli ATCC 8739 trimethylamine-N-oxide reductase c-type cytochrome TorC YP_001725557.1 2850659 R 481805 CDS YP_001725558.1 170020604 6066874 2851961..2852653 1 NC_010468.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 2852653 6066874 EcolC_2600 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator TorR YP_001725558.1 2851961 D 481805 CDS YP_001725559.1 170020605 6066895 complement(2852626..2853654) 1 NC_010468.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 2853654 6066895 EcolC_2601 Escherichia coli ATCC 8739 TMAO reductase system periplasmic protein TorT YP_001725559.1 2852626 R 481805 CDS YP_001725560.1 170020606 6065036 2853767..2856481 1 NC_010468.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 2856481 6065036 EcolC_2602 Escherichia coli ATCC 8739 hybrid sensory histidine kinase TorS YP_001725560.1 2853767 D 481805 CDS YP_001725561.1 170020607 6067048 2856553..2857626 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_1002 hypothetical protein; 4Fe-4S ferredoxin 2857626 6067048 EcolC_2603 Escherichia coli ATCC 8739 4Fe-4S ferredoxin YP_001725561.1 2856553 D 481805 CDS YP_001725562.1 170020608 6065104 complement(2857675..2857848) 1 NC_010468.1 PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA; GnsAGnsB family protein 2857848 6065104 EcolC_2604 Escherichia coli ATCC 8739 GnsAGnsB family protein YP_001725562.1 2857675 R 481805 CDS YP_001725563.1 170020609 6064837 complement(2857838..2858068) 1 NC_010468.1 KEGG: ssn:SSON_0998 Sfa; cold shock gene 2858068 6064837 EcolC_2605 Escherichia coli ATCC 8739 cold shock gene YP_001725563.1 2857838 R 481805 CDS YP_001725564.1 170020610 6065439 complement(2858043..2858255) 1 NC_010468.1 KEGG: sec:SC1999 putative cold-shock protein; putative cold-shock protein 2858255 6065439 EcolC_2606 Escherichia coli ATCC 8739 putative cold-shock protein YP_001725564.1 2858043 R 481805 CDS YP_001725565.1 170020611 6065907 complement(2858242..2858454) 1 NC_010468.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sbo:SBO_2241 CspG; cold shock protein CspG 2858454 6065907 EcolC_2607 Escherichia coli ATCC 8739 cold shock protein CspG YP_001725565.1 2858242 R 481805 CDS YP_001725566.1 170020612 6064443 2858740..2858952 1 NC_010468.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sdy:SDY_0964 cold shock-like protein; cold-shock DNA-binding domain-containing protein 2858952 6064443 EcolC_2608 Escherichia coli ATCC 8739 cold-shock DNA-binding domain-containing protein YP_001725566.1 2858740 D 481805 CDS YP_001725567.1 170020613 6067505 2859393..2859698 1 NC_010468.1 KEGG: sdy:SDY_0963 hypothetical protein; hypothetical protein 2859698 6067505 EcolC_2609 Escherichia coli ATCC 8739 hypothetical protein YP_001725567.1 2859393 D 481805 CDS YP_001725568.1 170020614 6065535 2859805..2860449 1 NC_010468.1 KEGG: sbo:SBO_2244 putative regulator; putative regulator 2860449 6065535 EcolC_2610 Escherichia coli ATCC 8739 putative regulator YP_001725568.1 2859805 D 481805 CDS YP_001725569.1 170020615 6066892 2860446..2861192 1 NC_010468.1 PFAM: protein of unknown function DUF1017; KEGG: ssn:SSON_0992 hypothetical protein; hypothetical protein 2861192 6066892 EcolC_2611 Escherichia coli ATCC 8739 hypothetical protein YP_001725569.1 2860446 D 481805 CDS YP_001725570.1 170020616 6065159 2861192..2863288 1 NC_010468.1 PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: sbo:SBO_2246 hypothetical protein; hypothetical protein 2863288 6065159 EcolC_2612 Escherichia coli ATCC 8739 hypothetical protein YP_001725570.1 2861192 D 481805 CDS YP_001725571.1 170020617 6065570 2863334..2864473 1 NC_010468.1 PFAM: polysaccharide export protein; KEGG: ssn:SSON_0990 putative function in exopolysaccharide production; polysaccharide export protein 2864473 6065570 EcolC_2613 Escherichia coli ATCC 8739 polysaccharide export protein YP_001725571.1 2863334 D 481805 CDS YP_001725572.1 170020618 6065181 2864461..2864907 1 NC_010468.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 2864907 etp 6065181 etp Escherichia coli ATCC 8739 phosphotyrosine-protein phosphatase YP_001725572.1 2864461 D 481805 CDS YP_001725573.1 170020619 6064656 2864927..2867107 1 NC_010468.1 KEGG: sbo:SBO_2249 hypothetical protein; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; cryptic autophosphorylating protein tyrosine kinase Etk 2867107 6064656 EcolC_2615 Escherichia coli ATCC 8739 cryptic autophosphorylating protein tyrosine kinase Etk YP_001725573.1 2864927 D 481805 CDS YP_001725574.1 170020620 6066031 complement(2867222..2868550) 1 NC_010468.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_0987 phosphoanhydride phosphorylase; phosphoanhydride phosphorylase 2868550 6066031 EcolC_2616 Escherichia coli ATCC 8739 phosphoanhydride phosphorylase YP_001725574.1 2867222 R 481805 CDS YP_001725575.1 170020621 6067059 complement(2868705..2869841) 1 NC_010468.1 KEGG: ssn:SSON_0985 probable third cytochrome oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 2869841 6067059 EcolC_2617 Escherichia coli ATCC 8739 cytochrome d ubiquinol oxidase subunit II YP_001725575.1 2868705 R 481805 CDS YP_001725576.1 170020622 6065624 complement(2869853..2871397) 1 NC_010468.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sfv:SFV_0987 probable third cytochrome oxidase, subunit I; cytochrome bd ubiquinol oxidase subunit I 2871397 6065624 EcolC_2618 Escherichia coli ATCC 8739 cytochrome bd ubiquinol oxidase subunit I YP_001725576.1 2869853 R 481805 CDS YP_001725577.1 170020623 6066232 complement(2871531..2872388) 1 NC_010468.1 PFAM: HupH hydrogenase expression protein; KEGG: sfx:S1045 hydrogenase-1 operon protein hyaF; HupH hydrogenase expression protein 2872388 6066232 EcolC_2619 Escherichia coli ATCC 8739 HupH hydrogenase expression protein YP_001725577.1 2871531 R 481805 CDS YP_001725578.1 170020624 6064910 complement(2872385..2872783) 1 NC_010468.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 2872783 6064910 EcolC_2620 Escherichia coli ATCC 8739 hydrogenase-1 operon protein HyaE YP_001725578.1 2872385 R 481805 CDS YP_001725579.1 170020625 6064644 complement(2872780..2873367) 1 NC_010468.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 2873367 6064644 EcolC_2621 Escherichia coli ATCC 8739 hydrogenase 1 maturation protease YP_001725579.1 2872780 R 481805 CDS YP_001725580.1 170020626 6065412 complement(2873364..2874071) 1 NC_010468.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: sdy:SDY_0949 probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit; hydrogenase 1 b-type cytochrome subunit 2874071 6065412 EcolC_2622 Escherichia coli ATCC 8739 hydrogenase 1 b-type cytochrome subunit YP_001725580.1 2873364 R 481805 CDS YP_001725581.1 170020627 6065752 2875066..2876217 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30; integrase catalytic subunit 2876217 6065752 EcolC_2624 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001725581.1 2875066 D 481805 CDS YP_001725582.1 170020628 6066223 complement(2877103..2878221) 1 NC_010468.1 KEGG: sdy:SDY_0947 hydrogenase-1 small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein; hydrogenase (NiFe) small subunit HydA 2878221 6066223 EcolC_2625 Escherichia coli ATCC 8739 hydrogenase (NiFe) small subunit HydA YP_001725582.1 2877103 R 481805 CDS YP_001725583.1 170020629 6066065 2878942..2879601 1 NC_010468.1 PFAM: protein of unknown function UPF0005; KEGG: sdy:SDY_0945 putative carrier/transport protein; hypothetical protein 2879601 6066065 EcolC_2626 Escherichia coli ATCC 8739 hypothetical protein YP_001725583.1 2878942 D 481805 CDS YP_001725584.1 170020630 6064826 2879692..2880021 1 NC_010468.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 2880021 6064826 EcolC_2627 Escherichia coli ATCC 8739 sulfur transfer protein TusE YP_001725584.1 2879692 D 481805 CDS YP_001725585.1 170020631 6065184 complement(2880018..2880296) 1 NC_010468.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 2880296 6065184 EcolC_2628 Escherichia coli ATCC 8739 acylphosphatase YP_001725585.1 2880018 R 481805 CDS YP_001725586.1 170020632 6064665 2880391..2881581 1 NC_010468.1 PFAM: conserved hypothetical protein; SMART: PUA domain containing protein; KEGG: sdy:SDY_0942 hypothetical protein; hypothetical protein 2881581 6064665 EcolC_2629 Escherichia coli ATCC 8739 hypothetical protein YP_001725586.1 2880391 D 481805 CDS YP_001725587.1 170020633 6067298 2881639..2881956 1 NC_010468.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: sbo:SBO_2265 hypothetical protein; heat shock protein HspQ 2881956 6067298 EcolC_2630 Escherichia coli ATCC 8739 heat shock protein HspQ YP_001725587.1 2881639 D 481805 CDS YP_001725588.1 170020634 6067444 complement(2882001..2882414) 1 NC_010468.1 PFAM: CoA-binding domain protein; KEGG: sbo:SBO_2266 hypothetical protein; CoA-binding domain-containing protein 2882414 6067444 EcolC_2631 Escherichia coli ATCC 8739 CoA-binding domain-containing protein YP_001725588.1 2882001 R 481805 CDS YP_001725589.1 170020635 6064562 2882587..2883249 1 NC_010468.1 KEGG: sdy:SDY_0939 hypothetical protein; hypothetical protein 2883249 6064562 EcolC_2632 Escherichia coli ATCC 8739 hypothetical protein YP_001725589.1 2882587 D 481805 CDS YP_001725590.1 170020636 6064585 2883345..2883803 1 NC_010468.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 2883803 mgsA 6064585 mgsA Escherichia coli ATCC 8739 methylglyoxal synthase YP_001725590.1 2883345 D 481805 CDS YP_001725591.1 170020637 6066111 complement(2883835..2885889) 1 NC_010468.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 2885889 helD 6066111 helD Escherichia coli ATCC 8739 DNA helicase IV YP_001725591.1 2883835 R 481805 CDS YP_001725592.1 170020638 6066495 2886012..2886458 1 NC_010468.1 PFAM: protein of unknown function DUF307; KEGG: sbo:SBO_2270 hypothetical protein; hypothetical protein 2886458 6066495 EcolC_2635 Escherichia coli ATCC 8739 hypothetical protein YP_001725592.1 2886012 D 481805 CDS YP_001725593.1 170020639 6066133 2886468..2888630 1 NC_010468.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_0964 hypothetical protein; hypothetical protein 2888630 6066133 EcolC_2636 Escherichia coli ATCC 8739 hypothetical protein YP_001725593.1 2886468 D 481805 CDS YP_001725594.1 170020640 6064522 complement(2888593..2889222) 1 NC_010468.1 PFAM: TfoX domain protein; KEGG: sdy:SDY_0934 hypothetical protein; competence-specific genes regulator 2889222 6064522 EcolC_2637 Escherichia coli ATCC 8739 competence-specific genes regulator YP_001725594.1 2888593 R 481805 CDS YP_001725595.1 170020641 6067662 2889441..2889950 1 NC_010468.1 PFAM: cell division inhibitor SulA; KEGG: ssn:SSON_0962 suppressor of lon; inhibits cell division and FtsZ ring formation; SOS cell division inhibitor 2889950 6067662 EcolC_2638 Escherichia coli ATCC 8739 SOS cell division inhibitor YP_001725595.1 2889441 D 481805 CDS YP_001725596.1 170020642 6065730 2890250..2891347 1 NC_010468.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 2891347 6065730 EcolC_2639 Escherichia coli ATCC 8739 outer membrane protein A YP_001725596.1 2890250 D 481805 CDS YP_001725597.1 170020643 6065371 complement(2891423..2891875) 1 NC_010468.1 PFAM: protein of unknown function DUF1047; KEGG: sdy:SDY_0929 putative dehydrogenase; hypothetical protein 2891875 6065371 EcolC_2640 Escherichia coli ATCC 8739 hypothetical protein YP_001725597.1 2891423 R 481805 CDS YP_001725598.1 170020644 6065885 2892061..2893821 1 NC_010468.1 PFAM: peptidase S16 lon domain protein; KEGG: ssn:SSON_0959 putative ATP-dependent protease; peptidase S16 lon domain-containing protein 2893821 6065885 EcolC_2641 Escherichia coli ATCC 8739 peptidase S16 lon domain-containing protein YP_001725598.1 2892061 D 481805 CDS YP_001725599.1 170020645 6065493 2893890..2894408 1 NC_010468.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2894408 6065493 EcolC_2642 Escherichia coli ATCC 8739 3-hydroxydecanoyl-ACP dehydratase YP_001725599.1 2893890 D 481805 CDS YP_001725600.1 170020646 6066587 complement(2894478..2894645) 1 NC_010468.1 PFAM: ribosome modulation factor; KEGG: sdy:SDY_0926 ribosome modulation factor; ribosome modulation factor 2894645 6066587 EcolC_2643 Escherichia coli ATCC 8739 ribosome modulation factor YP_001725600.1 2894478 R 481805 CDS YP_001725601.1 170020647 6066386 complement(2894901..2895464) 1 NC_010468.1 PFAM: protein of unknown function DUF330; KEGG: sfv:SFV_0961 hypothetical protein; hypothetical protein 2895464 6066386 EcolC_2644 Escherichia coli ATCC 8739 hypothetical protein YP_001725601.1 2894901 R 481805 CDS YP_001725602.1 170020648 6067438 complement(2895461..2897101) 1 NC_010468.1 PFAM: Mammalian cell entry related domain protein; KEGG: sdy:SDY_0924 paraquat-inducible protein B; paraquat-inducible protein B 2897101 6067438 EcolC_2645 Escherichia coli ATCC 8739 paraquat-inducible protein B YP_001725602.1 2895461 R 481805 CDS YP_001725603.1 170020649 6066809 complement(2897106..2898359) 1 NC_010468.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: sbo:SBO_2281 paraquat-inducible protein A; PqiA family integral membrane protein 2898359 6066809 EcolC_2646 Escherichia coli ATCC 8739 PqiA family integral membrane protein YP_001725603.1 2897106 R 481805 CDS YP_001725604.1 170020650 6064666 complement(2898489..2900396) 1 NC_010468.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 2900396 6064666 EcolC_2647 Escherichia coli ATCC 8739 ABC transporter ATPase YP_001725604.1 2898489 R 481805 CDS YP_001725605.1 170020651 6064872 complement(2900408..2902516) 1 NC_010468.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 2902516 rlmL 6064872 rlmL Escherichia coli ATCC 8739 23S rRNA m(2)G2445 methyltransferase YP_001725605.1 2900408 R 481805 CDS YP_001725606.1 170020652 6067399 2902760..2903869 1 NC_010468.1 PFAM: ferredoxin; MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: ssn:SSON_0951 hypothetical protein; MOSC domain-containing protein 2903869 6067399 EcolC_2649 Escherichia coli ATCC 8739 MOSC domain-containing protein YP_001725606.1 2902760 D 481805 CDS YP_001725607.1 170020653 6064435 complement(2903866..2904408) 1 NC_010468.1 PFAM: protein of unknown function DUF1379; KEGG: ssn:SSON_0950 hypothetical protein; hypothetical protein 2904408 6064435 EcolC_2650 Escherichia coli ATCC 8739 hypothetical protein YP_001725607.1 2903866 R 481805 CDS YP_001725608.1 170020654 6065395 complement(2904582..2905592) 1 NC_010468.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2905592 6065395 EcolC_2651 Escherichia coli ATCC 8739 dihydroorotate dehydrogenase 2 YP_001725608.1 2904582 R 481805 CDS YP_001725609.1 170020655 6064807 complement(2905703..2906413) 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_0948 putative chaperone; pili assembly chaperone 2906413 6064807 EcolC_2652 Escherichia coli ATCC 8739 pili assembly chaperone YP_001725609.1 2905703 R 481805 CDS YP_001725610.1 170020656 6064411 complement(2906406..2906921) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0947 putative fimbrial-like protein; fimbrial protein 2906921 6064411 EcolC_2653 Escherichia coli ATCC 8739 fimbrial protein YP_001725610.1 2906406 R 481805 CDS YP_001725611.1 170020657 6064795 complement(2906929..2907471) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: sfv:SFV_0951 putative fimbrial-like protein; fimbrial protein 2907471 6064795 EcolC_2654 Escherichia coli ATCC 8739 fimbrial protein YP_001725611.1 2906929 R 481805 CDS YP_001725612.1 170020658 6064444 complement(2907483..2908526) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0945 FimH-like protein; fimbrial protein 2908526 6064444 EcolC_2655 Escherichia coli ATCC 8739 fimbrial protein YP_001725612.1 2907483 R 481805 CDS YP_001725613.1 170020659 6067217 complement(2911168..2911869) 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_0943 putative chaperone; pili assembly chaperone 2911869 6067217 EcolC_2657 Escherichia coli ATCC 8739 pili assembly chaperone YP_001725613.1 2911168 R 481805 CDS YP_001725614.1 170020660 6066964 complement(2911952..2912491) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0942 putative fimbrial-like protein; fimbrial protein 2912491 6066964 EcolC_2658 Escherichia coli ATCC 8739 fimbrial protein YP_001725614.1 2911952 R 481805 CDS YP_001725615.1 170020661 6066868 2912847..2913422 1 NC_010468.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2228 hypothetical protein; NAD(P)H-dependent FMN reductase 2913422 6066868 EcolC_2659 Escherichia coli ATCC 8739 NAD(P)H-dependent FMN reductase YP_001725615.1 2912847 D 481805 CDS YP_001725616.1 170020662 6065549 2913415..2914374 1 NC_010468.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 2914374 6065549 EcolC_2660 Escherichia coli ATCC 8739 alkanesulfonate transporter substrate-binding subunit YP_001725616.1 2913415 D 481805 CDS YP_001725617.1 170020663 6067484 2914371..2915516 1 NC_010468.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 2915516 6067484 EcolC_2661 Escherichia coli ATCC 8739 alkanesulfonate monooxygenase YP_001725617.1 2914371 D 481805 CDS YP_001725618.1 170020664 6066525 2915527..2916318 1 NC_010468.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 2916318 ssuC 6066525 ssuC Escherichia coli ATCC 8739 alkanesulfonate transporter permease YP_001725618.1 2915527 D 481805 CDS YP_001725619.1 170020665 6065366 2916315..2917082 1 NC_010468.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 2917082 ssuB 6065366 ssuB Escherichia coli ATCC 8739 aliphatic sulfonates transport ATP-binding subunit YP_001725619.1 2916315 D 481805 CDS YP_001725620.1 170020666 6064622 complement(2917125..2919737) 1 NC_010468.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: sbo:SBO_2223 aminopeptidase N; aminopeptidase N 2919737 pepN 6064622 pepN Escherichia coli ATCC 8739 aminopeptidase N YP_001725620.1 2917125 R 481805 CDS YP_001725621.1 170020667 6065100 2919955..2921205 1 NC_010468.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2921205 6065100 EcolC_2665 Escherichia coli ATCC 8739 nicotinate phosphoribosyltransferase YP_001725621.1 2919955 D 481805 CDS YP_001725622.1 170020668 6066122 2921374..2922774 1 NC_010468.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 2922774 asnC 6066122 asnC Escherichia coli ATCC 8739 asparaginyl-tRNA synthetase YP_001725622.1 2921374 D 481805 CDS YP_001725623.1 170020669 6067636 2923376..2924464 1 NC_010468.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 2924464 6067636 EcolC_2667 Escherichia coli ATCC 8739 outer membrane protein F YP_001725623.1 2923376 D 481805 CDS YP_001725624.1 170020670 6066780 2924649..2925839 1 NC_010468.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 2925839 6066780 EcolC_2668 Escherichia coli ATCC 8739 aromatic amino acid aminotransferase YP_001725624.1 2924649 D 481805 CDS YP_001725625.1 170020671 6065874 complement(2926061..2926708) 1 NC_010468.1 PFAM: beta-lactamase domain protein; KEGG: sbo:SBO_2218 hypothetical protein; beta-lactamase domain-containing protein 2926708 6065874 EcolC_2669 Escherichia coli ATCC 8739 beta-lactamase domain-containing protein YP_001725625.1 2926061 R 481805 CDS YP_001725626.1 170020672 6066309 complement(2926735..2927283) 1 NC_010468.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: sdy:SDY_2331 hypothetical protein; hypothetical protein 2927283 6066309 EcolC_2670 Escherichia coli ATCC 8739 hypothetical protein YP_001725626.1 2926735 R 481805 CDS YP_001725627.1 170020673 6065460 complement(2927464..2929311) 1 NC_010468.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sbo:SBO_2216 putative amidase; hypothetical protein 2929311 6065460 EcolC_2671 Escherichia coli ATCC 8739 hypothetical protein YP_001725627.1 2927464 R 481805 CDS YP_001725628.1 170020674 6065096 complement(2929572..2934032) 1 NC_010468.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 2934032 mukB 6065096 mukB Escherichia coli ATCC 8739 cell division protein MukB YP_001725628.1 2929572 R 481805 CDS YP_001725629.1 170020675 6065798 complement(2934032..2934736) 1 NC_010468.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 2934736 6065798 EcolC_2673 Escherichia coli ATCC 8739 condesin subunit E YP_001725629.1 2934032 R 481805 CDS YP_001725630.1 170020676 6065477 complement(2934717..2936039) 1 NC_010468.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 2936039 6065477 EcolC_2674 Escherichia coli ATCC 8739 condesin subunit F YP_001725630.1 2934717 R 481805 CDS YP_001725631.1 170020677 6067038 complement(2936036..2936821) 1 NC_010468.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 2936821 6067038 EcolC_2675 Escherichia coli ATCC 8739 putative metallothionein SmtA YP_001725631.1 2936036 R 481805 CDS YP_001725632.1 170020678 6065449 2936957..2937736 1 NC_010468.1 PFAM: protein of unknown function DUF218; KEGG: sfv:SFV_0921 hypothetical protein; hypothetical protein 2937736 6065449 EcolC_2676 Escherichia coli ATCC 8739 hypothetical protein YP_001725632.1 2936957 D 481805 CDS YP_001725633.1 170020679 6067572 complement(2937713..2938606) 1 NC_010468.1 KEGG: sbo:SBO_2207 hypothetical protein; hypothetical protein 2938606 6067572 EcolC_2677 Escherichia coli ATCC 8739 hypothetical protein YP_001725633.1 2937713 R 481805 CDS YP_001725634.1 170020680 6065401 complement(2938760..2939506) 1 NC_010468.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 2939506 6065401 EcolC_2678 Escherichia coli ATCC 8739 3-deoxy-manno-octulosonate cytidylyltransferase YP_001725634.1 2938760 R 481805 CDS YP_001725635.1 170020681 6066307 complement(2939503..2939685) 1 NC_010468.1 PFAM: protein of unknown function DUF343; KEGG: sdy:SDY_2341 hypothetical protein; hypothetical protein 2939685 6066307 EcolC_2679 Escherichia coli ATCC 8739 hypothetical protein YP_001725635.1 2939503 R 481805 CDS YP_001725636.1 170020682 6065633 complement(2939737..2940969) 1 NC_010468.1 PFAM: protein of unknown function DUF1006; KEGG: sdy:SDY_2342 hypothetical protein; hypothetical protein 2940969 6065633 EcolC_2680 Escherichia coli ATCC 8739 hypothetical protein YP_001725636.1 2939737 R 481805 CDS YP_001725637.1 170020683 6066672 complement(2941006..2941992) 1 NC_010468.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 2941992 lpxK 6066672 lpxK Escherichia coli ATCC 8739 tetraacyldisaccharide 4'-kinase YP_001725637.1 2941006 R 481805 CDS YP_001725638.1 170020684 6064648 complement(2941989..2943737) 1 NC_010468.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 2943737 6064648 EcolC_2682 Escherichia coli ATCC 8739 lipid transporter ATP-binding protein/permease YP_001725638.1 2941989 R 481805 CDS YP_001725639.1 170020685 6066407 complement(2943774..2946038) 1 NC_010468.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: sdy:SDY_2345 hypothetical protein; hypothetical protein 2946038 6066407 EcolC_2683 Escherichia coli ATCC 8739 hypothetical protein YP_001725639.1 2943774 R 481805 CDS YP_001725640.1 170020686 6065915 complement(2946246..2946530) 1 NC_010468.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 2946530 ihfB 6065915 ihfB Escherichia coli ATCC 8739 integration host factor subunit beta YP_001725640.1 2946246 R 481805 CDS YP_001725641.1 170020687 6065333 complement(2946690..2948363) 1 NC_010468.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 2948363 rpsA 6065333 rpsA Escherichia coli ATCC 8739 30S ribosomal protein S1 YP_001725641.1 2946690 R 481805 CDS YP_001725642.1 170020688 6066310 complement(2948474..2949157) 1 NC_010468.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 2949157 cmk 6066310 cmk Escherichia coli ATCC 8739 cytidylate kinase YP_001725642.1 2948474 R 481805 CDS YP_001725643.1 170020689 6066220 complement(2949330..2950094) 1 NC_010468.1 PFAM: peptidase M48 Ste24p; KEGG: ssn:SSON_0911 putative heat shock protein; peptidase M48 Ste24p 2950094 6066220 EcolC_2687 Escherichia coli ATCC 8739 peptidase M48 Ste24p YP_001725643.1 2949330 R 481805 CDS YP_001725644.1 170020690 6066710 complement(2950263..2951546) 1 NC_010468.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 2951546 6066710 EcolC_2688 Escherichia coli ATCC 8739 3-phosphoshikimate 1-carboxyvinyltransferase YP_001725644.1 2950263 R 481805 CDS YP_001725645.1 170020691 6066377 complement(2951617..2952705) 1 NC_010468.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 2952705 6066377 EcolC_2689 Escherichia coli ATCC 8739 phosphoserine aminotransferase YP_001725645.1 2951617 R 481805 CDS YP_001725646.1 170020692 6064483 complement(2952904..2953596) 1 NC_010468.1 PFAM: protein of unknown function DUF421; KEGG: sbo:SBO_2192 hypothetical protein; hypothetical protein 2953596 6064483 EcolC_2690 Escherichia coli ATCC 8739 hypothetical protein YP_001725646.1 2952904 R 481805 CDS YP_001725647.1 170020693 6067591 2953726..2955486 1 NC_010468.1 PFAM: protein of unknown function DUF181; KEGG: sbo:SBO_2191 hypothetical protein; hypothetical protein 2955486 6067591 EcolC_2691 Escherichia coli ATCC 8739 hypothetical protein YP_001725647.1 2953726 D 481805 CDS YP_001725648.1 170020694 6064555 2955892..2956749 1 NC_010468.1 PFAM: formate/nitrite transporter; KEGG: sdy:SDY_2357 probable formate transporter; formate transporter 2956749 6064555 EcolC_2692 Escherichia coli ATCC 8739 formate transporter YP_001725648.1 2955892 D 481805 CDS YP_001725649.1 170020695 6066389 2956804..2959086 1 NC_010468.1 KEGG: ssn:SSON_0904 formate acetyltransferase 1; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; formate acetyltransferase 2959086 6066389 EcolC_2693 Escherichia coli ATCC 8739 formate acetyltransferase YP_001725649.1 2956804 D 481805 CDS YP_001725650.1 170020696 6065768 2959278..2960018 1 NC_010468.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 2960018 pflA 6065768 pflA Escherichia coli ATCC 8739 pyruvate formate lyase-activating enzyme 1 YP_001725650.1 2959278 D 481805 CDS YP_001725651.1 170020697 6066399 complement(2960100..2960690) 1 NC_010468.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2185 hypothetical protein; hypothetical protein 2960690 6066399 EcolC_2695 Escherichia coli ATCC 8739 hypothetical protein YP_001725651.1 2960100 R 481805 CDS YP_001725652.1 170020698 6065708 2960790..2961698 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2184 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2961698 6065708 EcolC_2696 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725652.1 2960790 D 481805 CDS YP_001725653.1 170020699 6067061 complement(2961699..2963129) 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: stm:STM0969 putative amino-acid transporter; amino acid permease-associated protein 2963129 6067061 EcolC_2697 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001725653.1 2961699 R 481805 CDS YP_001725654.1 170020700 6065426 complement(2963339..2964487) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_2363 putative transport; putative MFS family transporter protein 2964487 6065426 EcolC_2698 Escherichia coli ATCC 8739 putative MFS family transporter protein YP_001725654.1 2963339 R 481805 CDS YP_001725655.1 170020701 6067517 2964801..2965427 1 NC_010468.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_0898 hypothetical protein; isochorismatase hydrolase 2965427 6067517 EcolC_2699 Escherichia coli ATCC 8739 isochorismatase hydrolase YP_001725655.1 2964801 D 481805 CDS YP_001725656.1 170020702 6067192 complement(2965462..2966325) 1 NC_010468.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_0985 anaerobic dimethyl sulfoxide reductase subunit C; DMSO reductase anchor subunit DmsC 2966325 6067192 EcolC_2700 Escherichia coli ATCC 8739 DMSO reductase anchor subunit DmsC YP_001725656.1 2965462 R 481805 CDS YP_001725657.1 170020703 6065729 complement(2966327..2966944) 1 NC_010468.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_0896 anaerobic dimethyl sulfoxide reductase subunit B; dimethylsulfoxide reductase subunit B 2966944 6065729 EcolC_2701 Escherichia coli ATCC 8739 dimethylsulfoxide reductase subunit B YP_001725657.1 2966327 R 481805 CDS YP_001725658.1 170020704 6065590 complement(2966955..2969399) 1 NC_010468.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: ssn:SSON_0895 anaerobic dimethyl sulfoxide reductase subunit A; anaerobic dimethyl sulfoxide reductase subunit A 2969399 6065590 EcolC_2702 Escherichia coli ATCC 8739 anaerobic dimethyl sulfoxide reductase subunit A YP_001725658.1 2966955 R 481805 CDS YP_001725659.1 170020705 6067125 complement(2969638..2970930) 1 NC_010468.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 2970930 6067125 EcolC_2703 Escherichia coli ATCC 8739 seryl-tRNA synthetase YP_001725659.1 2969638 R 481805 CDS YP_001725660.1 170020706 6065710 complement(2971021..2972364) 1 NC_010468.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: sdy:SDY_2369 putative polynucleotide enzyme; recombination factor protein RarA 2972364 6065710 EcolC_2704 Escherichia coli ATCC 8739 recombination factor protein RarA YP_001725660.1 2971021 R 481805 CDS YP_001725661.1 170020707 6066662 complement(2972375..2972986) 1 NC_010468.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 2972986 lolA 6066662 lolA Escherichia coli ATCC 8739 outer-membrane lipoprotein carrier protein YP_001725661.1 2972375 R 481805 CDS YP_001725662.1 170020708 6065818 complement(2973141..2977130) 1 NC_010468.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 2977130 6065818 EcolC_2706 Escherichia coli ATCC 8739 DNA translocase FtsK YP_001725662.1 2973141 R 481805 CDS YP_001725663.1 170020709 6065592 complement(2977265..2977759) 1 NC_010468.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 2977759 6065592 EcolC_2707 Escherichia coli ATCC 8739 leucine-responsive transcriptional regulator YP_001725663.1 2977265 R 481805 CDS YP_001725664.1 170020710 6065088 2978304..2979269 1 NC_010468.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 2979269 6065088 EcolC_2708 Escherichia coli ATCC 8739 thioredoxin reductase YP_001725664.1 2978304 D 481805 CDS YP_001725665.1 170020711 6064814 2979392..2981158 1 NC_010468.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 2981158 6064814 EcolC_2709 Escherichia coli ATCC 8739 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001725665.1 2979392 D 481805 CDS YP_001725666.1 170020712 6066944 2981159..2982880 1 NC_010468.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 2982880 6066944 EcolC_2710 Escherichia coli ATCC 8739 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001725666.1 2981159 D 481805 CDS YP_001725667.1 170020713 6067642 2982922..2983626 1 NC_010468.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 2983626 aat 6067642 aat Escherichia coli ATCC 8739 leucyl/phenylalanyl-tRNA--protein transferase YP_001725667.1 2982922 D 481805 CDS YP_001725668.1 170020714 6067646 2983911..2984129 1 NC_010468.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2984129 infA 6067646 infA Escherichia coli ATCC 8739 translation initiation factor IF-1 YP_001725668.1 2983911 D 481805 CDS YP_001725669.1 170020715 6064735 complement(join(2986831..2987274,2987274..2987528)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 2987528 6064735 EcolC_2714 Escherichia coli ATCC 8739 insertion element protein YP_001725669.1 2986831 R 481805 CDS YP_001725670.1 170020716 6067613 complement(2988011..2988331) 1 NC_010468.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 2988331 clpS 6067613 clpS Escherichia coli ATCC 8739 ATP-dependent Clp protease adaptor protein ClpS YP_001725670.1 2988011 R 481805 CDS YP_001725671.1 170020717 6067416 2988654..2988878 1 NC_010468.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 2988878 6067416 EcolC_2716 Escherichia coli ATCC 8739 stationary phase/starvation inducible regulatory protein CspD YP_001725671.1 2988654 D 481805 CDS YP_001725672.1 170020718 6067230 complement(2988951..2990897) 1 NC_010468.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 2990897 6067230 EcolC_2717 Escherichia coli ATCC 8739 macrolide transporter ATP-binding /permease YP_001725672.1 2988951 R 481805 CDS YP_001725673.1 170020719 6066808 complement(2990894..2992009) 1 NC_010468.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 2992009 6066808 EcolC_2718 Escherichia coli ATCC 8739 macrolide transporter subunit MacA YP_001725673.1 2990894 R 481805 CDS YP_001725674.1 170020720 6066734 2992124..2993116 1 NC_010468.1 PFAM: protein of unknown function DUF535; KEGG: ssn:SSON_0864 putative enzyme; hypothetical protein 2993116 6066734 EcolC_2719 Escherichia coli ATCC 8739 hypothetical protein YP_001725674.1 2992124 D 481805 CDS YP_001725675.1 170020721 6066620 complement(2993113..2994771) 1 NC_010468.1 KEGG: sfx:S0876 predicted ATP-dependent endonuclease of the OLD family; ATP-dependent OLD family endonuclease 2994771 6066620 EcolC_2720 Escherichia coli ATCC 8739 ATP-dependent OLD family endonuclease YP_001725675.1 2993113 R 481805 CDS YP_001725676.1 170020722 6066518 2995196..2995891 1 NC_010468.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 2995891 6066518 EcolC_2721 Escherichia coli ATCC 8739 aquaporin Z YP_001725676.1 2995196 D 481805 CDS YP_001725677.1 170020723 6066464 2996386..2997285 1 NC_010468.1 PFAM: protein of unknown function DUF340 membrane; KEGG: sbo:SBO_0807 putative surface protein; hypothetical protein 2997285 6066464 EcolC_2722 Escherichia coli ATCC 8739 hypothetical protein YP_001725677.1 2996386 D 481805 CDS YP_001725678.1 170020724 6066423 2997429..2999081 1 NC_010468.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 2999081 6066423 EcolC_2723 Escherichia coli ATCC 8739 hydroxylamine reductase YP_001725678.1 2997429 D 481805 CDS YP_001725679.1 170020725 6066329 2999093..3000061 1 NC_010468.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ssn:SSON_0858 putative enzyme; HCP oxidoreductase 3000061 6066329 EcolC_2724 Escherichia coli ATCC 8739 HCP oxidoreductase YP_001725679.1 2999093 D 481805 CDS YP_001725680.1 170020726 6066040 3000194..3001912 1 NC_010468.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 3001912 6066040 EcolC_2725 Escherichia coli ATCC 8739 pyruvate dehydrogenase YP_001725680.1 3000194 D 481805 CDS YP_001725681.1 170020727 6065806 3001949..3002950 1 NC_010468.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 3002950 6065806 EcolC_2726 Escherichia coli ATCC 8739 L-threonine aldolase YP_001725681.1 3001949 D 481805 CDS YP_001725682.1 170020728 6064912 3002961..3004391 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sbo:SBO_0802 putative dTDP-glucose enzyme; NAD-dependent epimerase/dehydratase 3004391 6064912 EcolC_2727 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001725682.1 3002961 D 481805 CDS YP_001725683.1 170020729 6064962 3004454..3005503 1 NC_010468.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: ssn:SSON_0854 putative nucleotide di-P-sugar epimerase or dehydratase; NAD-dependent epimerase/dehydratase 3005503 6064962 EcolC_2728 Escherichia coli ATCC 8739 NAD-dependent epimerase/dehydratase YP_001725683.1 3004454 D 481805 CDS YP_001725684.1 170020730 6065038 complement(3005500..3006330) 1 NC_010468.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sdy:SDY_2396 putative regulator; N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD 3006330 6065038 EcolC_2729 Escherichia coli ATCC 8739 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_001725684.1 3005500 R 481805 CDS YP_001725685.1 170020731 6066843 complement(3006327..3006650) 1 NC_010468.1 PFAM: protein of unknown function DUF74; KEGG: sdy:SDY_2397 hypothetical protein; hypothetical protein 3006650 6066843 EcolC_2730 Escherichia coli ATCC 8739 hypothetical protein YP_001725685.1 3006327 R 481805 CDS YP_001725686.1 170020732 6067648 3006776..3007291 1 NC_010468.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein 3007291 6067648 EcolC_2731 Escherichia coli ATCC 8739 putative lipoprotein YP_001725686.1 3006776 D 481805 CDS YP_001725687.1 170020733 6067450 3007509..3008237 1 NC_010468.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 3008237 artP 6067450 artP Escherichia coli ATCC 8739 arginine transporter ATP-binding subunit YP_001725687.1 3007509 D 481805 CDS YP_001725688.1 170020734 6067281 3008255..3008986 1 NC_010468.1 KEGG: sbo:SBO_0797 arginine 3rd transport system periplasmic binding protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; cationic amino acid ABC transporter periplasmic binding protein 3008986 6067281 EcolC_2733 Escherichia coli ATCC 8739 cationic amino acid ABC transporter periplasmic binding protein YP_001725688.1 3008255 D 481805 CDS YP_001725689.1 170020735 6066971 3008993..3009709 1 NC_010468.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease ArtQ 3009709 6066971 EcolC_2734 Escherichia coli ATCC 8739 arginine transporter permease ArtQ YP_001725689.1 3008993 D 481805 CDS YP_001725690.1 170020736 6066706 3009709..3010377 1 NC_010468.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease ArtM 3010377 artM 6066706 artM Escherichia coli ATCC 8739 arginine transporter permease ArtM YP_001725690.1 3009709 D 481805 CDS YP_001725691.1 170020737 6066159 3010603..3011334 1 NC_010468.1 KEGG: sbo:SBO_0794 arginine 3rd transport system periplasmic binding protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; cationic amino acid ABC transporter periplasmic binding protein 3011334 6066159 EcolC_2736 Escherichia coli ATCC 8739 cationic amino acid ABC transporter periplasmic binding protein YP_001725691.1 3010603 D 481805 CDS YP_001725692.1 170020738 6065898 complement(3011533..3012660) 1 NC_010468.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 3012660 rumB 6065898 rumB Escherichia coli ATCC 8739 23S rRNA methyluridine methyltransferase YP_001725692.1 3011533 R 481805 CDS YP_001725693.1 170020739 6065887 complement(3012701..3013189) 1 NC_010468.1 KEGG: sdy:SDY_0737 hypothetical protein; hypothetical protein 3013189 6065887 EcolC_2738 Escherichia coli ATCC 8739 hypothetical protein YP_001725693.1 3012701 R 481805 CDS YP_001725694.1 170020740 6065714 complement(3013249..3014094) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_0738 putrescine transport protein; putrescine ABC transporter membrane protein 3014094 6065714 EcolC_2739 Escherichia coli ATCC 8739 putrescine ABC transporter membrane protein YP_001725694.1 3013249 R 481805 CDS YP_001725695.1 170020741 6065690 complement(3014091..3015044) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfx:S0852 putrescine transport protein; permease; putrescine ABC transporter membrane protein 3015044 6065690 EcolC_2740 Escherichia coli ATCC 8739 putrescine ABC transporter membrane protein YP_001725695.1 3014091 R 481805 CDS YP_001725696.1 170020742 6065567 complement(3015054..3016187) 1 NC_010468.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 3016187 potG 6065567 potG Escherichia coli ATCC 8739 putrescine ABC transporter ATP-binding protein YP_001725696.1 3015054 R 481805 CDS YP_001725697.1 170020743 6065194 complement(3016282..3017394) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_0788 periplasmic putrescine-binding protein; putrescine ABC transporter periplasmic-binding protein 3017394 6065194 EcolC_2742 Escherichia coli ATCC 8739 putrescine ABC transporter periplasmic-binding protein YP_001725697.1 3016282 R 481805 CDS YP_001725698.1 170020744 6064906 complement(3017745..3018221) 1 NC_010468.1 KEGG: sbo:SBO_0787 putative sensory transduction regulator; putative sensory transduction regulator 3018221 6064906 EcolC_2743 Escherichia coli ATCC 8739 putative sensory transduction regulator YP_001725698.1 3017745 R 481805 CDS YP_001725699.1 170020745 6064780 complement(3018309..3019211) 1 NC_010468.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 3019211 6064780 EcolC_2744 Escherichia coli ATCC 8739 ribosomal protein S6 modification protein YP_001725699.1 3018309 R 481805 CDS YP_001725700.1 170020746 6064707 complement(3019272..3019994) 1 NC_010468.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 3019994 6064707 EcolC_2745 Escherichia coli ATCC 8739 nitroreductase A YP_001725700.1 3019272 R 481805 CDS YP_001725701.1 170020747 6064667 complement(3019978..3020265) 1 NC_010468.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 3020265 6064667 EcolC_2746 Escherichia coli ATCC 8739 hypothetical protein YP_001725701.1 3019978 R 481805 CDS YP_001725702.1 170020748 6066103 3020425..3020682 1 NC_010468.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 3020682 grxA 6066103 grxA Escherichia coli ATCC 8739 glutaredoxin YP_001725702.1 3020425 D 481805 CDS YP_001725703.1 170020749 6065214 complement(3020712..3021089) 1 NC_010468.1 KEGG: sdy:SDY_0747 hypothetical protein; hypothetical protein 3021089 6065214 EcolC_2748 Escherichia coli ATCC 8739 hypothetical protein YP_001725703.1 3020712 R 481805 CDS YP_001725704.1 170020750 6065377 3021359..3023044 1 NC_010468.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: ssn:SSON_0832 putative transport protein; hypothetical protein 3023044 6065377 EcolC_2749 Escherichia coli ATCC 8739 hypothetical protein YP_001725704.1 3021359 D 481805 CDS YP_001725705.1 170020751 6066747 complement(3023280..3023498) 1 NC_010468.1 PFAM: transcriptional activator Ogr/delta; KEGG: sbo:SBO_0780 putative bacteriophage late gene regulator; transcriptional activator Ogr/delta 3023498 6066747 EcolC_2750 Escherichia coli ATCC 8739 transcriptional activator Ogr/delta YP_001725705.1 3023280 R 481805 CDS YP_001725706.1 170020752 6065632 complement(3023589..3024689) 1 NC_010468.1 PFAM: late control D family protein; KEGG: stt:t3444 putative regulator of late gene expression; late control D family protein 3024689 6065632 EcolC_2751 Escherichia coli ATCC 8739 late control D family protein YP_001725706.1 3023589 R 481805 CDS YP_001725707.1 170020753 6064973 complement(3024686..3025171) 1 NC_010468.1 PFAM: P2 GpU family protein; KEGG: sbo:SBO_0778 putative bacteriophage tail protein; P2 GpU family protein 3025171 6064973 EcolC_2752 Escherichia coli ATCC 8739 P2 GpU family protein YP_001725707.1 3024686 R 481805 CDS YP_001725708.1 170020754 6066221 complement(3025168..3028245) 1 NC_010468.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: stt:t2662 putative bacteriophage tail protein; TP901 family phage tail tape measure protein 3028245 6066221 EcolC_2753 Escherichia coli ATCC 8739 TP901 family phage tail tape measure protein YP_001725708.1 3025168 R 481805 CDS YP_001725709.1 170020755 6065226 complement(3028372..3028674) 1 NC_010468.1 PFAM: tail E family protein; KEGG: sbo:SBO_0776 putative phage tail protein; tail E family protein 3028674 6065226 EcolC_2754 Escherichia coli ATCC 8739 tail E family protein YP_001725709.1 3028372 R 481805 CDS YP_001725710.1 170020756 6067431 complement(3028729..3029244) 1 NC_010468.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: sbo:SBO_0775 probable major tail tube protein; phage major tail tube protein 3029244 6067431 EcolC_2755 Escherichia coli ATCC 8739 phage major tail tube protein YP_001725710.1 3028729 R 481805 CDS YP_001725711.1 170020757 6065615 complement(3029254..3030426) 1 NC_010468.1 PFAM: tail sheath protein; KEGG: sbo:SBO_0774 probable major tail sheath protein; tail sheath protein 3030426 6065615 EcolC_2756 Escherichia coli ATCC 8739 tail sheath protein YP_001725711.1 3029254 R 481805 CDS YP_001725712.1 170020758 6067229 complement(3030569..3031135) 1 NC_010468.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: sbo:SBO_0773 inversion of adjacent DNA; at locus of E14 element; resolvase domain-containing protein 3031135 6067229 EcolC_2757 Escherichia coli ATCC 8739 resolvase domain-containing protein YP_001725712.1 3030569 R 481805 CDS YP_001725713.1 170020759 6064768 3031163..3031696 1 NC_010468.1 PFAM: Tail Collar domain protein; KEGG: stt:t1351 bacteriophage tail fiber protein; tail collar domain-containing protein 3031696 6064768 EcolC_2758 Escherichia coli ATCC 8739 tail collar domain-containing protein YP_001725713.1 3031163 D 481805 CDS YP_001725714.1 170020760 6064773 3031696..3032298 1 NC_010468.1 PFAM: tail assembly chaperone gp38; KEGG: stt:t1349 putative bacteriophage tail fiber assembly protein; tail assembly chaperone gp38 3032298 6064773 EcolC_2759 Escherichia coli ATCC 8739 tail assembly chaperone gp38 YP_001725714.1 3031696 D 481805 CDS YP_001725715.1 170020761 6064782 complement(3032270..3032689) 1 NC_010468.1 PFAM: tail assembly chaperone gp38; KEGG: sbo:SBO_0772 hypothetical protein; tail assembly chaperone gp38 3032689 6064782 EcolC_2760 Escherichia coli ATCC 8739 tail assembly chaperone gp38 YP_001725715.1 3032270 R 481805 CDS YP_001725716.1 170020762 6064783 complement(3032686..3034107) 1 NC_010468.1 KEGG: stt:t3433 probable variable tail fiber protein; phage-related tail fiber protein-like protein 3034107 6064783 EcolC_2761 Escherichia coli ATCC 8739 phage-related tail fiber protein-like protein YP_001725716.1 3032686 R 481805 CDS YP_001725717.1 170020763 6064790 complement(3034104..3034709) 1 NC_010468.1 TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: stt:t4306 putative phage tail protein; phage tail protein I 3034709 6064790 EcolC_2762 Escherichia coli ATCC 8739 phage tail protein I YP_001725717.1 3034104 R 481805 CDS YP_001725718.1 170020764 6064797 complement(3034702..3035610) 1 NC_010468.1 PFAM: Baseplate J family protein; KEGG: stt:t3431 phage baseplate assembly protein; baseplate J family protein 3035610 6064797 EcolC_2763 Escherichia coli ATCC 8739 baseplate J family protein YP_001725718.1 3034702 R 481805 CDS YP_001725719.1 170020765 6064802 complement(3035597..3035956) 1 NC_010468.1 PFAM: GPW/gp25 family protein; KEGG: stt:t3430 phage baseplate assembly protein; GPW/gp25 family protein 3035956 6064802 EcolC_2764 Escherichia coli ATCC 8739 GPW/gp25 family protein YP_001725719.1 3035597 R 481805 CDS YP_001725720.1 170020766 6064805 complement(3035953..3036531) 1 NC_010468.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: stt:t3429 putative phage baseplate assembly protein; phage baseplate assembly protein V 3036531 6064805 EcolC_2765 Escherichia coli ATCC 8739 phage baseplate assembly protein V YP_001725720.1 3035953 R 481805 CDS YP_001725721.1 170020767 6064812 complement(3036658..3038169) 1 NC_010468.1 KEGG: dps:DP2013 hypothetical protein; hypothetical protein 3038169 6064812 EcolC_2766 Escherichia coli ATCC 8739 hypothetical protein YP_001725721.1 3036658 R 481805 CDS YP_001725722.1 170020768 6064816 complement(3038257..3038721) 1 NC_010468.1 TIGRFAM: phage virion morphogenesis protein; PFAM: virion morphogenesis (putative tail completion) protein; KEGG: stt:t3428 putative phage tail protein; phage virion morphogenesis protein 3038721 6064816 EcolC_2767 Escherichia coli ATCC 8739 phage virion morphogenesis protein YP_001725722.1 3038257 R 481805 CDS YP_001725723.1 170020769 6064821 complement(3038714..3039145) 1 NC_010468.1 PFAM: P2 phage tail completion R family protein; KEGG: stt:t3427 putative phage tail protein; P2 phage tail completion R family protein 3039145 6064821 EcolC_2768 Escherichia coli ATCC 8739 P2 phage tail completion R family protein YP_001725723.1 3038714 R 481805 CDS YP_001725724.1 170020770 6064824 complement(3039241..3039669) 1 NC_010468.1 KEGG: stm:STM2714 lysis-like protein; lysis-like protein 3039669 6064824 EcolC_2769 Escherichia coli ATCC 8739 lysis-like protein YP_001725724.1 3039241 R 481805 CDS YP_001725725.1 170020771 6064831 complement(3039666..3040181) 1 NC_010468.1 PFAM: glycoside hydrolase family 24; KEGG: sbo:SBO_0765 putative lysozyme protein R of prophage CP-933K; glycoside hydrolase family protein 3040181 6064831 EcolC_2770 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001725725.1 3039666 R 481805 CDS YP_001725726.1 170020772 6064835 complement(3040162..3040377) 1 NC_010468.1 KEGG: stt:t3423 possible secretory protein; putative secretory protein 3040377 6064835 EcolC_2771 Escherichia coli ATCC 8739 putative secretory protein YP_001725726.1 3040162 R 481805 CDS YP_001725727.1 170020773 6064836 complement(3040381..3040584) 1 NC_010468.1 PFAM: tail X family protein; KEGG: stt:t3422 probable phage tail protein; tail X family protein 3040584 6064836 EcolC_2772 Escherichia coli ATCC 8739 tail X family protein YP_001725727.1 3040381 R 481805 CDS YP_001725728.1 170020774 6064846 complement(3040584..3041048) 1 NC_010468.1 PFAM: head completion protein; KEGG: sbo:SBO_0762 putative capsid completion protein; head completion protein 3041048 6064846 EcolC_2773 Escherichia coli ATCC 8739 head completion protein YP_001725728.1 3040584 R 481805 CDS YP_001725729.1 170020775 6064851 complement(3041144..3041794) 1 NC_010468.1 PFAM: small terminase subunit; KEGG: stt:t3420 terminase, endonuclease subunit; small terminase subunit 3041794 6064851 EcolC_2774 Escherichia coli ATCC 8739 small terminase subunit YP_001725729.1 3041144 R 481805 CDS YP_001725730.1 170020776 6064857 complement(3041798..3042856) 1 NC_010468.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: stt:t3419 major capsid protein; P2 family phage major capsid protein 3042856 6064857 EcolC_2775 Escherichia coli ATCC 8739 P2 family phage major capsid protein YP_001725730.1 3041798 R 481805 CDS YP_001725731.1 170020777 6064858 complement(3042873..3043706) 1 NC_010468.1 PFAM: capsid scaffolding; KEGG: stt:t3418 putative capsid scaffolding protein; capsid scaffolding 3043706 6064858 EcolC_2776 Escherichia coli ATCC 8739 capsid scaffolding YP_001725731.1 3042873 R 481805 CDS YP_001725732.1 170020778 6064863 3043849..3045615 1 NC_010468.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: stt:t3417 terminase, ATPase subunit; hypothetical protein 3045615 6064863 EcolC_2777 Escherichia coli ATCC 8739 hypothetical protein YP_001725732.1 3043849 D 481805 CDS YP_001725733.1 170020779 6064866 3045615..3046640 1 NC_010468.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: stt:t3416 probable capsid portal protein; PBSX family phage portal protein 3046640 6064866 EcolC_2778 Escherichia coli ATCC 8739 PBSX family phage portal protein YP_001725733.1 3045615 D 481805 CDS YP_001725734.1 170020780 6064874 complement(3047010..3047660) 1 NC_010468.1 hypothetical protein 3047660 6064874 EcolC_2779 Escherichia coli ATCC 8739 hypothetical protein YP_001725734.1 3047010 R 481805 CDS YP_001725735.1 170020781 6064875 complement(3047666..3048361) 1 NC_010468.1 KEGG: cbe:Cbei_0882 hypothetical protein; hypothetical protein 3048361 6064875 EcolC_2780 Escherichia coli ATCC 8739 hypothetical protein YP_001725735.1 3047666 R 481805 CDS YP_001725736.1 170020782 6064881 complement(3048642..3049319) 1 NC_010468.1 KEGG: stm:STM2726 hypothetical protein; hypothetical protein 3049319 6064881 EcolC_2781 Escherichia coli ATCC 8739 hypothetical protein YP_001725736.1 3048642 R 481805 CDS YP_001725737.1 170020783 6064886 complement(3049433..3049666) 1 NC_010468.1 PFAM: DinI family protein; KEGG: sbo:SBO_0753 putative damage-inducible protein; DinI family protein 3049666 6064886 EcolC_2782 Escherichia coli ATCC 8739 DinI family protein YP_001725737.1 3049433 R 481805 CDS YP_001725738.1 170020784 6064892 complement(3049677..3049865) 1 NC_010468.1 KEGG: stt:t3411 hypothetical protein; hypothetical protein 3049865 6064892 EcolC_2783 Escherichia coli ATCC 8739 hypothetical protein YP_001725738.1 3049677 R 481805 CDS YP_001725739.1 170020785 6064893 complement(3050018..3052390) 1 NC_010468.1 PFAM: replication gene A; KEGG: stt:t3410 possible endonuclease; replication gene A 3052390 6064893 EcolC_2784 Escherichia coli ATCC 8739 replication gene A YP_001725739.1 3050018 R 481805 CDS YP_001725740.1 170020786 6064896 complement(3052390..3053211) 1 NC_010468.1 KEGG: eba:ebA7273 hypothetical protein; hypothetical protein 3053211 6064896 EcolC_2785 Escherichia coli ATCC 8739 hypothetical protein YP_001725740.1 3052390 R 481805 CDS YP_001725741.1 170020787 6064901 complement(3053217..3054071) 1 NC_010468.1 KEGG: stt:t3409 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; DNA adenine methylase 3054071 6064901 EcolC_2786 Escherichia coli ATCC 8739 DNA adenine methylase YP_001725741.1 3053217 R 481805 CDS YP_001725742.1 170020788 6064904 complement(3054068..3054295) 1 NC_010468.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: stt:t3408 hypothetical protein; TraR/DksA family transcriptional regulator 3054295 6064904 EcolC_2787 Escherichia coli ATCC 8739 TraR/DksA family transcriptional regulator YP_001725742.1 3054068 R 481805 CDS YP_001725743.1 170020789 6064909 complement(3054295..3054528) 1 NC_010468.1 KEGG: stt:t3407 hypothetical protein; hypothetical protein 3054528 6064909 EcolC_2788 Escherichia coli ATCC 8739 hypothetical protein YP_001725743.1 3054295 R 481805 CDS YP_001725744.1 170020790 6064914 complement(3054596..3054937) 1 NC_010468.1 KEGG: stt:t3406 hypothetical protein; hypothetical protein 3054937 6064914 EcolC_2789 Escherichia coli ATCC 8739 hypothetical protein YP_001725744.1 3054596 R 481805 CDS YP_001725745.1 170020791 6064916 complement(3054901..3055101) 1 NC_010468.1 KEGG: ent:Ent638_1345 hypothetical protein; hypothetical protein 3055101 6064916 EcolC_2790 Escherichia coli ATCC 8739 hypothetical protein YP_001725745.1 3054901 R 481805 CDS YP_001725746.1 170020792 6064918 complement(3055109..3055618) 1 NC_010468.1 PFAM: regulatory CII family protein; KEGG: stt:t3404 regulatory protein CII; regulatory CII family protein 3055618 6064918 EcolC_2791 Escherichia coli ATCC 8739 regulatory CII family protein YP_001725746.1 3055109 R 481805 CDS YP_001725747.1 170020793 6064925 complement(3055651..3055872) 1 NC_010468.1 KEGG: sbo:SBO_0749 hypothetical protein; hypothetical protein 3055872 6064925 EcolC_2792 Escherichia coli ATCC 8739 hypothetical protein YP_001725747.1 3055651 R 481805 CDS YP_001725748.1 170020794 6064928 3055998..3056567 1 NC_010468.1 PFAM: CI repressor; KEGG: sbo:SBO_0748 repressor protein; CI repressor 3056567 6064928 EcolC_2793 Escherichia coli ATCC 8739 CI repressor YP_001725748.1 3055998 D 481805 CDS YP_001725749.1 170020795 6064929 3056583..3056774 1 NC_010468.1 KEGG: sdy:SDY_1763 hypothetical protein; hypothetical protein 3056774 6064929 EcolC_2794 Escherichia coli ATCC 8739 hypothetical protein YP_001725749.1 3056583 D 481805 CDS YP_001725750.1 170020796 6064946 3056961..3058013 1 NC_010468.1 PFAM: integrase family protein; KEGG: stt:t3400 probable bacteriophage integrase; integrase family protein 3058013 6064946 EcolC_2795 Escherichia coli ATCC 8739 integrase family protein YP_001725750.1 3056961 D 481805 CDS YP_001725751.1 170020797 6064947 complement(3058118..3058654) 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: sbo:SBO_0742 putative DeoR-type transcriptional regulator; TetR family transcriptional regulator 3058654 6064947 EcolC_2796 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001725751.1 3058118 R 481805 CDS YP_001725752.1 170020798 6064949 3058819..3059946 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_0741 putative DeoR-type transcriptional regulator; major facilitator transporter 3059946 6064949 EcolC_2797 Escherichia coli ATCC 8739 major facilitator transporter YP_001725752.1 3058819 D 481805 CDS YP_001725753.1 170020799 6064954 3059946..3060761 1 NC_010468.1 KEGG: sfv:SFV_0829 hypothetical protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3; cof family hydrolase 3060761 6064954 EcolC_2798 Escherichia coli ATCC 8739 cof family hydrolase YP_001725753.1 3059946 D 481805 CDS YP_001725754.1 170020800 6064958 3060847..3061131 1 NC_010468.1 KEGG: sbo:SBO_0739 hypothetical protein; hypothetical protein 3061131 6064958 EcolC_2799 Escherichia coli ATCC 8739 hypothetical protein YP_001725754.1 3060847 D 481805 CDS YP_001725755.1 170020801 6064960 complement(3061172..3062404) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0838 chloramphenicol resistance pump Cmr; major facilitator transporter 3062404 6064960 EcolC_2800 Escherichia coli ATCC 8739 major facilitator transporter YP_001725755.1 3061172 R 481805 CDS YP_001725756.1 170020802 6064970 3062689..3063285 1 NC_010468.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_0826 hypothetical protein; undecaprenyl pyrophosphate phosphatase 3063285 6064970 EcolC_2801 Escherichia coli ATCC 8739 undecaprenyl pyrophosphate phosphatase YP_001725756.1 3062689 D 481805 CDS YP_001725757.1 170020803 6064987 3063343..3064101 1 NC_010468.1 PFAM: regulatory protein DeoR; KEGG: sfv:SFV_0825 transcriptional repressor for deo operon, tsx, NupG; DNA-binding transcriptional repressor DeoR 3064101 6064987 EcolC_2802 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor DeoR YP_001725757.1 3063343 D 481805 CDS YP_001725758.1 170020804 6064990 complement(3064148..3065350) 1 NC_010468.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3065350 6064990 EcolC_2803 Escherichia coli ATCC 8739 D-alanyl-D-alanine carboxypeptidase YP_001725758.1 3064148 R 481805 CDS YP_001725759.1 170020805 6064993 3065597..3066223 1 NC_010468.1 PFAM: Glutathione S-transferase domain; KEGG: sfx:S0831 putative transferase; glutathione S-transferase domain-containing protein 3066223 6064993 EcolC_2804 Escherichia coli ATCC 8739 glutathione S-transferase domain-containing protein YP_001725759.1 3065597 D 481805 CDS YP_001725760.1 170020806 6064995 complement(3066220..3067335) 1 NC_010468.1 PFAM: glucose sorbosone dehydrogenase; KEGG: sbo:SBO_0733 putative dehydrogenase; glucose sorbosone dehydrogenase 3067335 6064995 EcolC_2805 Escherichia coli ATCC 8739 glucose sorbosone dehydrogenase YP_001725760.1 3066220 R 481805 CDS YP_001725761.1 170020807 6064999 complement(3067446..3067829) 1 NC_010468.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 3067829 bssR 6064999 bssR Escherichia coli ATCC 8739 biofilm formation regulatory protein BssR YP_001725761.1 3067446 R 481805 CDS YP_001725762.1 170020808 6065001 3068042..3069367 1 NC_010468.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 3069367 rimO 6065001 rimO Escherichia coli ATCC 8739 ribosomal protein S12 methylthiotransferase YP_001725762.1 3068042 D 481805 CDS YP_001725763.1 170020809 6064521 3069593..3069979 1 NC_010468.1 PFAM: protein of unknown function DUF1044; KEGG: plu:plu2130 hypothetical protein; hypothetical protein 3069979 6064521 EcolC_2808 Escherichia coli ATCC 8739 hypothetical protein YP_001725763.1 3069593 D 481805 CDS YP_001725764.1 170020810 6065000 3069969..3070298 1 NC_010468.1 PFAM: helix-turn-helix domain protein; KEGG: shn:Shewana3_4237 transcriptional regulator, XRE family; XRE family transcriptional regulator 3070298 6065000 EcolC_2809 Escherichia coli ATCC 8739 XRE family transcriptional regulator YP_001725764.1 3069969 D 481805 CDS YP_001725765.1 170020811 6065018 complement(3070368..3071696) 1 NC_010468.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbo:SBO_0726 hypothetical protein; diguanylate cyclase 3071696 6065018 EcolC_2810 Escherichia coli ATCC 8739 diguanylate cyclase YP_001725765.1 3070368 R 481805 CDS YP_001725766.1 170020812 6065025 complement(3071704..3074052) 1 NC_010468.1 PFAM: EAL domain protein; KEGG: sfv:SFV_0816 hypothetical protein; diguanylate phosphodiesterase 3074052 6065025 EcolC_2811 Escherichia coli ATCC 8739 diguanylate phosphodiesterase YP_001725766.1 3071704 R 481805 CDS YP_001725767.1 170020813 6065029 complement(3074230..3075141) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_0722 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 3075141 6065029 EcolC_2812 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725767.1 3074230 R 481805 CDS YP_001725768.1 170020814 6065031 complement(3075144..3076064) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_0756 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 3076064 6065031 EcolC_2813 Escherichia coli ATCC 8739 binding-protein-dependent transport system inner membrane protein YP_001725768.1 3075144 R 481805 CDS YP_001725769.1 170020815 6065034 complement(3076082..3077620) 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_0720 putative transport protein; extracellular solute-binding protein 3077620 6065034 EcolC_2814 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001725769.1 3076082 R 481805 CDS YP_001725770.1 170020816 6065035 complement(3077640..3079511) 1 NC_010468.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 3079511 6065035 EcolC_2815 Escherichia coli ATCC 8739 glutathione transporter ATP-binding protein YP_001725770.1 3077640 R 481805 CDS YP_001725771.1 170020817 6065046 complement(3079498..3080463) 1 NC_010468.1 PFAM: peptidase T2 asparaginase 2; KEGG: sfx:S0821 putative asparaginase; L-asparaginase 3080463 6065046 EcolC_2816 Escherichia coli ATCC 8739 L-asparaginase YP_001725771.1 3079498 R 481805 CDS YP_001725772.1 170020818 6065049 3080667..3081902 1 NC_010468.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 3081902 6065049 EcolC_2817 Escherichia coli ATCC 8739 molybdopterin biosynthesis protein MoeA YP_001725772.1 3080667 D 481805 CDS YP_001725773.1 170020819 6065056 3081902..3082651 1 NC_010468.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 3082651 6065056 EcolC_2818 Escherichia coli ATCC 8739 molybdopterin biosynthesis protein MoeB YP_001725773.1 3081902 D 481805 CDS YP_001725774.1 170020820 6064883 complement(3082727..3083389) 1 NC_010468.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 3083389 6064883 EcolC_2819 Escherichia coli ATCC 8739 fructose-6-phosphate aldolase YP_001725774.1 3082727 R 481805 CDS YP_001725775.1 170020821 6065067 3083520..3084419 1 NC_010468.1 KEGG: sfv:SFV_0807 putative pyruvate formate-lyase 2 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein; glycyl-radical activating family protein 3084419 6065067 EcolC_2820 Escherichia coli ATCC 8739 glycyl-radical activating family protein YP_001725775.1 3083520 D 481805 CDS YP_001725776.1 170020822 6065071 3084425..3086857 1 NC_010468.1 KEGG: ssn:SSON_0805 putative formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; pyruvate formate-lyase 3086857 6065071 EcolC_2821 Escherichia coli ATCC 8739 pyruvate formate-lyase YP_001725776.1 3084425 D 481805 CDS YP_001725777.1 170020823 6065072 3086997..3087812 1 NC_010468.1 KEGG: sfv:SFV_0805 hypothetical protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; cof family hydrolase 3087812 6065072 EcolC_2822 Escherichia coli ATCC 8739 cof family hydrolase YP_001725777.1 3086997 D 481805 CDS YP_001725778.1 170020824 6065075 complement(3088845..3090437) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0710 putative ATP-binding component of a transport system; ABC transporter-like protein 3090437 6065075 EcolC_2823 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725778.1 3088845 R 481805 CDS YP_001725779.1 170020825 6065078 3090656..3091576 1 NC_010468.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_0777 hypothetical protein; hypothetical protein 3091576 6065078 EcolC_2824 Escherichia coli ATCC 8739 hypothetical protein YP_001725779.1 3090656 D 481805 CDS YP_001725780.1 170020826 6064698 complement(3091635..3092753) 1 NC_010468.1 PFAM: Citrate transporter; KEGG: ssn:SSON_0797 hypothetical protein; citrate transporter 3092753 6064698 EcolC_2825 Escherichia coli ATCC 8739 citrate transporter YP_001725780.1 3091635 R 481805 CDS YP_001725781.1 170020827 6065085 complement(3092750..3093217) 1 NC_010468.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 3093217 6065085 EcolC_2826 Escherichia coli ATCC 8739 manganese transport regulator MntR YP_001725781.1 3092750 R 481805 CDS YP_001725782.1 170020828 6065090 3093403..3093531 1 NC_010468.1 KEGG: sec:SC0831 hypothetical protein; hypothetical protein 3093531 6065090 EcolC_2827 Escherichia coli ATCC 8739 hypothetical protein YP_001725782.1 3093403 D 481805 CDS YP_001725783.1 170020829 6065091 3093803..3095386 1 NC_010468.1 PFAM: sulfatase; KEGG: sbo:SBO_0706 putative enzyme; sulfatase 3095386 6065091 EcolC_2828 Escherichia coli ATCC 8739 sulfatase YP_001725783.1 3093803 D 481805 CDS YP_001725784.1 170020830 6065093 complement(3095435..3095950) 1 NC_010468.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 3095950 ompX 6065093 ompX Escherichia coli ATCC 8739 outer membrane protein X YP_001725784.1 3095435 R 481805 CDS YP_001725785.1 170020831 6065094 3096303..3097190 1 NC_010468.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_0793 putative transmembrane subunit; threonine and homoserine efflux system 3097190 6065094 EcolC_2830 Escherichia coli ATCC 8739 threonine and homoserine efflux system YP_001725785.1 3096303 D 481805 CDS YP_001725786.1 170020832 6065101 3097489..3097992 1 NC_010468.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 3097992 6065101 EcolC_2831 Escherichia coli ATCC 8739 DNA starvation/stationary phase protection protein Dps YP_001725786.1 3097489 D 481805 CDS YP_001725787.1 170020833 6065103 3098396..3099142 1 NC_010468.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 3099142 glnH 6065103 glnH Escherichia coli ATCC 8739 glutamine ABC transporter periplasmic protein YP_001725787.1 3098396 D 481805 CDS YP_001725788.1 170020834 6065108 3099281..3099940 1 NC_010468.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 3099940 glnP 6065108 glnP Escherichia coli ATCC 8739 glutamine ABC transporter permease YP_001725788.1 3099281 D 481805 CDS YP_001725789.1 170020835 6065113 3099937..3100659 1 NC_010468.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 3100659 glnQ 6065113 glnQ Escherichia coli ATCC 8739 glutamine ABC transporter ATP-binding protein YP_001725789.1 3099937 D 481805 CDS YP_001725790.1 170020836 6065118 3100920..3103145 1 NC_010468.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0788 putative transport protein; hypothetical protein 3103145 6065118 EcolC_2835 Escherichia coli ATCC 8739 hypothetical protein YP_001725790.1 3100920 D 481805 CDS YP_001725791.1 170020837 6065130 complement(3103142..3104068) 1 NC_010468.1 PFAM: protein of unknown function DUF890; KEGG: sbo:SBO_0697 hypothetical protein; putative SAM-dependent methyltransferase 3104068 6065130 EcolC_2836 Escherichia coli ATCC 8739 putative SAM-dependent methyltransferase YP_001725791.1 3103142 R 481805 CDS YP_001725792.1 170020838 6065131 3104344..3104604 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: ssn:SSON_0786 hypothetical protein; hypothetical protein 3104604 6065131 EcolC_2837 Escherichia coli ATCC 8739 hypothetical protein YP_001725792.1 3104344 D 481805 CDS YP_001725793.1 170020839 6065134 3104869..3107151 1 NC_010468.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 3107151 6065134 EcolC_2838 Escherichia coli ATCC 8739 catecholate siderophore receptor Fiu YP_001725793.1 3104869 D 481805 CDS YP_001725794.1 170020840 6064977 3107193..3107870 1 NC_010468.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: sbo:SBO_0692 putative enzyme; putative hydroxylase 3107870 6064977 EcolC_2839 Escherichia coli ATCC 8739 putative hydroxylase YP_001725794.1 3107193 D 481805 CDS YP_001725795.1 170020841 6065138 3107944..3108210 1 NC_010468.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: ssn:SSON_0782 hypothetical protein; hypothetical protein 3108210 6065138 EcolC_2840 Escherichia coli ATCC 8739 hypothetical protein YP_001725795.1 3107944 D 481805 CDS YP_001725796.1 170020842 6065142 3108475..3108735 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: sfv:SFV_0785 hypothetical protein; hypothetical protein 3108735 6065142 EcolC_2841 Escherichia coli ATCC 8739 hypothetical protein YP_001725796.1 3108475 D 481805 CDS YP_001725797.1 170020843 6065144 complement(3108964..3110049) 1 NC_010468.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: ssn:SSON_0780 putative dehydrogenase; hypothetical protein 3110049 6065144 EcolC_2842 Escherichia coli ATCC 8739 hypothetical protein YP_001725797.1 3108964 R 481805 CDS YP_001725798.1 170020844 6065145 complement(3110190..3111152) 1 NC_010468.1 PFAM: glycosyl transferase family 3; KEGG: sbo:SBO_0688 putative enzyme; glycosyl transferase family protein 3111152 6065145 EcolC_2843 Escherichia coli ATCC 8739 glycosyl transferase family protein YP_001725798.1 3110190 R 481805 CDS YP_001725799.1 170020845 6065147 complement(3111180..3113330) 1 NC_010468.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 3113330 dinG 6065147 dinG Escherichia coli ATCC 8739 ATP-dependent DNA helicase DinG YP_001725799.1 3111180 R 481805 CDS YP_001725800.1 170020846 6064940 3113483..3113932 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_0686 hypothetical protein; hypothetical protein 3113932 6064940 EcolC_2845 Escherichia coli ATCC 8739 hypothetical protein YP_001725800.1 3113483 D 481805 CDS YP_001725801.1 170020847 6065153 complement(3114164..3115528) 1 NC_010468.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 3115528 6065153 EcolC_2846 Escherichia coli ATCC 8739 ATP-dependent RNA helicase RhlE YP_001725801.1 3114164 R 481805 CDS YP_001725802.1 170020848 6065154 3115757..3116428 1 NC_010468.1 PFAM: regulatory protein TetR; Transcriptional regulator TetR; KEGG: sdy:SDY_0807 putative transcriptional regulator; putative DNA-binding transcriptional regulator 3116428 6065154 EcolC_2847 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001725802.1 3115757 D 481805 CDS YP_001725803.1 170020849 6065162 3116431..3117426 1 NC_010468.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_0778 hypothetical protein; hypothetical protein 3117426 6065162 EcolC_2848 Escherichia coli ATCC 8739 hypothetical protein YP_001725803.1 3116431 D 481805 CDS YP_001725804.1 170020850 6065167 3117419..3119155 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfl:SF0744 putative ATP-binding component of a transport system; ABC transporter-like protein 3119155 6065167 EcolC_2849 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725804.1 3117419 D 481805 CDS YP_001725805.1 170020851 6065169 3119148..3120281 1 NC_010468.1 PFAM: ABC-2 type transporter; KEGG: ssn:SSON_0772 hypothetical protein; ABC-2 type transporter 3120281 6065169 EcolC_2850 Escherichia coli ATCC 8739 ABC-2 type transporter YP_001725805.1 3119148 D 481805 CDS YP_001725806.1 170020852 6065176 3120292..3121398 1 NC_010468.1 PFAM: ABC-2 type transporter; KEGG: ssn:SSON_0771 hypothetical protein; ABC-2 type transporter 3121398 6065176 EcolC_2851 Escherichia coli ATCC 8739 ABC-2 type transporter YP_001725806.1 3120292 D 481805 CDS YP_001725807.1 170020853 6065180 complement(3121360..3121770) 1 NC_010468.1 KEGG: sbo:SBO_0679 hypothetical protein; hypothetical protein 3121770 6065180 EcolC_2852 Escherichia coli ATCC 8739 hypothetical protein YP_001725807.1 3121360 R 481805 CDS YP_001725808.1 170020854 6065183 3121903..3122664 1 NC_010468.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ssn:SSON_0769 hypothetical protein; endonuclease/exonuclease/phosphatase 3122664 6065183 EcolC_2853 Escherichia coli ATCC 8739 endonuclease/exonuclease/phosphatase YP_001725808.1 3121903 D 481805 CDS YP_001725809.1 170020855 6065196 3122661..3123902 1 NC_010468.1 KEGG: ssn:SSON_0768 putative synthetase; cardiolipin synthase 2 3123902 6065196 EcolC_2854 Escherichia coli ATCC 8739 cardiolipin synthase 2 YP_001725809.1 3122661 D 481805 CDS YP_001725810.1 170020856 6065197 3123902..3124858 1 NC_010468.1 KEGG: sfv:SFV_0771 hypothetical protein; hypothetical protein 3124858 6065197 EcolC_2855 Escherichia coli ATCC 8739 hypothetical protein YP_001725810.1 3123902 D 481805 CDS YP_001725811.1 170020857 6065199 complement(3124894..3125607) 1 NC_010468.1 PFAM: protein of unknown function UPF0005; KEGG: sfv:SFV_0770 hypothetical protein; hypothetical protein 3125607 6065199 EcolC_2856 Escherichia coli ATCC 8739 hypothetical protein YP_001725811.1 3124894 R 481805 CDS YP_001725812.1 170020858 6065207 complement(3125812..3126516) 1 NC_010468.1 PFAM: protein of unknown function UPF0005; KEGG: sbo:SBO_0673 hypothetical protein; hypothetical protein 3126516 6065207 EcolC_2857 Escherichia coli ATCC 8739 hypothetical protein YP_001725812.1 3125812 R 481805 CDS YP_001725813.1 170020859 6065211 complement(3126654..3127106) 1 NC_010468.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 3127106 moaE 6065211 moaE Escherichia coli ATCC 8739 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_001725813.1 3126654 R 481805 CDS YP_001725814.1 170020860 6065220 complement(3127108..3127353) 1 NC_010468.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 3127353 moaD 6065220 moaD Escherichia coli ATCC 8739 molybdopterin synthase small subunit YP_001725814.1 3127108 R 481805 CDS YP_001725815.1 170020861 6065223 complement(3127346..3127831) 1 NC_010468.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 3127831 moaC 6065223 moaC Escherichia coli ATCC 8739 molybdenum cofactor biosynthesis protein MoaC YP_001725815.1 3127346 R 481805 CDS YP_001725816.1 170020862 6065228 complement(3127834..3128346) 1 NC_010468.1 TIGRFAM: molybdenum cofactor synthesis domain protein; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: sbo:SBO_0669 molybdopterin biosynthesis, protein B; molybdenum cofactor biosynthesis protein B 3128346 6065228 EcolC_2861 Escherichia coli ATCC 8739 molybdenum cofactor biosynthesis protein B YP_001725816.1 3127834 R 481805 CDS YP_001725817.1 170020863 6065234 complement(3128368..3129390) 1 NC_010468.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 3129390 moaA 6065234 moaA Escherichia coli ATCC 8739 molybdenum cofactor biosynthesis protein A YP_001725817.1 3128368 R 481805 CDS YP_001725818.1 170020864 6065239 3129754..3130662 1 NC_010468.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: sbo:SBO_0667 putative structural protein; hypothetical protein 3130662 6065239 EcolC_2863 Escherichia coli ATCC 8739 hypothetical protein YP_001725818.1 3129754 D 481805 CDS YP_001725819.1 170020865 6065246 complement(3130854..3132875) 1 NC_010468.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 3132875 6065246 EcolC_2864 Escherichia coli ATCC 8739 excinuclease ABC subunit B YP_001725819.1 3130854 R 481805 CDS YP_001725820.1 170020866 6065247 complement(3133454..3134131) 1 NC_010468.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 3134131 bioD 6065247 bioD Escherichia coli ATCC 8739 dithiobiotin synthetase YP_001725820.1 3133454 R 481805 CDS YP_001725821.1 170020867 6065251 complement(3134124..3134879) 1 NC_010468.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 3134879 6065251 EcolC_2866 Escherichia coli ATCC 8739 biotin biosynthesis protein BioC YP_001725821.1 3134124 R 481805 CDS YP_001725822.1 170020868 6065252 complement(3134866..3136020) 1 NC_010468.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 3136020 6065252 EcolC_2867 Escherichia coli ATCC 8739 8-amino-7-oxononanoate synthase YP_001725822.1 3134866 R 481805 CDS YP_001725823.1 170020869 6065110 complement(3136017..3137057) 1 NC_010468.1 KEGG: ssn:SSON_0754 biotin synthesis; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; biotin synthase 3137057 6065110 EcolC_2868 Escherichia coli ATCC 8739 biotin synthase YP_001725823.1 3136017 R 481805 CDS YP_001725824.1 170020870 6065257 3137201..3138433 1 NC_010468.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 3138433 6065257 EcolC_2869 Escherichia coli ATCC 8739 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001725824.1 3137201 D 481805 CDS YP_001725825.1 170020871 6065191 3138492..3138968 1 NC_010468.1 YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein 3138968 6065191 EcolC_2870 Escherichia coli ATCC 8739 putative kinase inhibitor protein YP_001725825.1 3138492 D 481805 CDS YP_001725826.1 170020872 6065277 complement(join(3139730..3140173,3140173..3140427)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: sdy:SDY_4618 IS1 ORF1; insertion element protein 3140427 6065277 EcolC_2872 Escherichia coli ATCC 8739 insertion element protein YP_001725826.1 3139730 R 481805 CDS YP_001725827.1 170020873 6065280 3140516..3140680 1 NC_010468.1 PFAM: Lambda phage regulatory protein CIII; KEGG: spt:SPA2420 hypothetical protein; lambda phage regulatory protein CIII 3140680 6065280 EcolC_2873 Escherichia coli ATCC 8739 lambda phage regulatory protein CIII YP_001725827.1 3140516 D 481805 CDS YP_001725828.1 170020874 6065281 3140523..3140792 1 NC_010468.1 PFAM: lambda Kil; lambda Kil 3140792 6065281 EcolC_2874 Escherichia coli ATCC 8739 lambda Kil YP_001725828.1 3140523 D 481805 CDS YP_001725829.1 170020875 6065285 3140868..3141164 1 NC_010468.1 PFAM: Host-nuclease inhibitor Gam; KEGG: sdy:SDY_1384 putative host-nuclease inhibitor protein Gam; host-nuclease inhibitor Gam 3141164 6065285 EcolC_2875 Escherichia coli ATCC 8739 host-nuclease inhibitor Gam YP_001725829.1 3140868 D 481805 CDS YP_001725830.1 170020876 6065288 3141170..3141955 1 NC_010468.1 TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: stt:t1923 bacteriophage recombination protein; phage recombination protein Bet 3141955 6065288 EcolC_2876 Escherichia coli ATCC 8739 phage recombination protein Bet YP_001725830.1 3141170 D 481805 CDS YP_001725831.1 170020877 6065292 3141952..3142632 1 NC_010468.1 PFAM: Exonuclease, phage-type; KEGG: sdy:SDY_1382 exonuclease; exodeoxyribonuclease 3142632 6065292 EcolC_2877 Escherichia coli ATCC 8739 exodeoxyribonuclease YP_001725831.1 3141952 D 481805 CDS YP_001725832.1 170020878 6065294 3142629..3142811 1 NC_010468.1 PFAM: protein of unknown function DUF1317; hypothetical protein 3142811 6065294 EcolC_2878 Escherichia coli ATCC 8739 hypothetical protein YP_001725832.1 3142629 D 481805 CDS YP_001725833.1 170020879 6065300 3142784..3142975 1 NC_010468.1 PFAM: protein of unknown function DUF1382; hypothetical protein 3142975 6065300 EcolC_2879 Escherichia coli ATCC 8739 hypothetical protein YP_001725833.1 3142784 D 481805 CDS YP_001725834.1 170020880 6065303 3142986..3143267 1 NC_010468.1 hypothetical protein 3143267 6065303 EcolC_2880 Escherichia coli ATCC 8739 hypothetical protein YP_001725834.1 3142986 D 481805 CDS YP_001725835.1 170020881 6065149 3143366..3143587 1 NC_010468.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: hit:NTHI1878 DnaK suppressor protein, bacteriophage PSP3 GP34 homolog; TraR/DksA family transcriptional regulator 3143587 6065149 EcolC_2881 Escherichia coli ATCC 8739 TraR/DksA family transcriptional regulator YP_001725835.1 3143366 D 481805 CDS YP_001725836.1 170020882 6065306 3143584..3143835 1 NC_010468.1 KEGG: sfv:SFV_0261 putative bacteriophage protein; putative bacteriophage protein 3143835 6065306 EcolC_2882 Escherichia coli ATCC 8739 putative bacteriophage protein YP_001725836.1 3143584 D 481805 CDS YP_001725837.1 170020883 6065317 complement(join(3144082..3144525,3144525..3144779)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 3144779 6065317 EcolC_2883 Escherichia coli ATCC 8739 insertion element protein YP_001725837.1 3144082 R 481805 CDS YP_001725838.1 170020884 6065321 3144892..3145506 1 NC_010468.1 KEGG: mes:Meso_1109 hypothetical protein; hypothetical protein 3145506 6065321 EcolC_2884 Escherichia coli ATCC 8739 hypothetical protein YP_001725838.1 3144892 D 481805 CDS YP_001725839.1 170020885 6064677 3145800..3146138 1 NC_010468.1 KEGG: yps:YPTB1765 putative GP46 [bacteriophage N15] pir||T13133 protein GP46-...; Contains selenocysteine; hypothetical protein 3146138 6064677 EcolC_2885 Escherichia coli ATCC 8739 hypothetical protein YP_001725839.1 3145800 D 481805 CDS YP_001725840.1 170020886 6065325 3146167..3146595 1 NC_010468.1 KEGG: cps:CPS_0896 hypothetical protein; hypothetical protein 3146595 6065325 EcolC_2886 Escherichia coli ATCC 8739 hypothetical protein YP_001725840.1 3146167 D 481805 CDS YP_001725841.1 170020887 6065326 3146678..3146845 1 NC_010468.1 hypothetical protein 3146845 6065326 EcolC_2887 Escherichia coli ATCC 8739 hypothetical protein YP_001725841.1 3146678 D 481805 CDS YP_001725842.1 170020888 6065329 3146885..3147103 1 NC_010468.1 PFAM: Excisionase domain protein; excisionase domain-containing protein 3147103 6065329 EcolC_2888 Escherichia coli ATCC 8739 excisionase domain-containing protein YP_001725842.1 3146885 D 481805 CDS YP_001725843.1 170020889 6065335 3147081..3148151 1 NC_010468.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; lambda integrase; KEGG: ssn:SSON_0746 putative integrase fragment; lambda integrase 3148151 6065335 EcolC_2889 Escherichia coli ATCC 8739 lambda integrase YP_001725843.1 3147081 D 481805 CDS YP_001725844.1 170020890 6065080 3148286..3149569 1 NC_010468.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase 3149569 6065080 EcolC_2890 Escherichia coli ATCC 8739 putative pectinesterase YP_001725844.1 3148286 D 481805 CDS YP_001725845.1 170020891 6065339 complement(3149803..3152064) 1 NC_010468.1 PFAM: aconitate hydratase domain protein; KEGG: sbo:SBO_0658 putative enzyme; hypothetical protein 3152064 6065339 EcolC_2891 Escherichia coli ATCC 8739 hypothetical protein YP_001725845.1 3149803 R 481805 CDS YP_001725846.1 170020892 6065341 complement(3152247..3153680) 1 NC_010468.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: sfv:SFV_0753 putative membrane pump protein; anion transporter 3153680 6065341 EcolC_2892 Escherichia coli ATCC 8739 anion transporter YP_001725846.1 3152247 R 481805 CDS YP_001725847.1 170020893 6065351 complement(3153756..3154808) 1 NC_010468.1 PFAM: protein of unknown function DUF453; KEGG: sfv:SFV_0752 hypothetical protein; hypothetical protein 3154808 6065351 EcolC_2893 Escherichia coli ATCC 8739 hypothetical protein YP_001725847.1 3153756 R 481805 CDS YP_001725848.1 170020894 6065357 3154992..3155945 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_0742 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 3155945 6065357 EcolC_2894 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725848.1 3154992 D 481805 CDS YP_001725849.1 170020895 6065358 complement(3155986..3156981) 1 NC_010468.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 3156981 6065358 EcolC_2895 Escherichia coli ATCC 8739 6-phosphogluconolactonase YP_001725849.1 3155986 R 481805 CDS YP_001725850.1 170020896 6065360 3157136..3157954 1 NC_010468.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 3157954 6065360 EcolC_2896 Escherichia coli ATCC 8739 phosphotransferase YP_001725850.1 3157136 D 481805 CDS YP_001725851.1 170020897 6065363 complement(3157955..3159013) 1 NC_010468.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 3159013 modC 6065363 modC Escherichia coli ATCC 8739 molybdate transporter ATP-binding protein YP_001725851.1 3157955 R 481805 CDS YP_001725852.1 170020898 6065364 complement(3159016..3159705) 1 NC_010468.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 3159705 modB 6065364 modB Escherichia coli ATCC 8739 molybdate ABC transporter permease YP_001725852.1 3159016 R 481805 CDS YP_001725853.1 170020899 6065365 complement(3159705..3160478) 1 NC_010468.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 3160478 modA 6065365 modA Escherichia coli ATCC 8739 molybdate transporter periplasmic protein YP_001725853.1 3159705 R 481805 CDS YP_001725854.1 170020900 6065369 complement(3160645..3160794) 1 NC_010468.1 KEGG: sdy:SDY_0709 hypothetical protein; hypothetical protein 3160794 6065369 EcolC_2900 Escherichia coli ATCC 8739 hypothetical protein YP_001725854.1 3160645 R 481805 CDS YP_001725855.1 170020901 6065373 3160923..3161711 1 NC_010468.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 3161711 6065373 EcolC_2901 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator ModE YP_001725855.1 3160923 D 481805 CDS YP_001725856.1 170020902 6065376 3161779..3163251 1 NC_010468.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 3163251 6065376 EcolC_2902 Escherichia coli ATCC 8739 putative molybdenum transport ATP-binding protein ModF YP_001725856.1 3161779 D 481805 CDS YP_001725857.1 170020903 6065378 3163512..3164528 1 NC_010468.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ssn:SSON_0711 UDP-galactose-4-epimerase; UDP-galactose-4-epimerase 3164528 6065378 EcolC_2903 Escherichia coli ATCC 8739 UDP-galactose-4-epimerase YP_001725857.1 3163512 D 481805 CDS YP_001725858.1 170020904 6065383 3164538..3165584 1 NC_010468.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 3165584 6065383 EcolC_2904 Escherichia coli ATCC 8739 galactose-1-phosphate uridylyltransferase YP_001725858.1 3164538 D 481805 CDS YP_001725859.1 170020905 6065384 3165588..3166736 1 NC_010468.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 3166736 6065384 EcolC_2905 Escherichia coli ATCC 8739 galactokinase YP_001725859.1 3165588 D 481805 CDS YP_001725860.1 170020906 6065388 3166730..3167770 1 NC_010468.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 3167770 galM 6065388 galM Escherichia coli ATCC 8739 aldose 1-epimerase YP_001725860.1 3166730 D 481805 CDS YP_001725861.1 170020907 6065403 3167972..3168724 1 NC_010468.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 3168724 gpmA 6065403 gpmA Escherichia coli ATCC 8739 phosphoglyceromutase YP_001725861.1 3167972 D 481805 CDS YP_001725862.1 170020908 6065406 complement(3168882..3169934) 1 NC_010468.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3169934 6065406 EcolC_2908 Escherichia coli ATCC 8739 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001725862.1 3168882 R 481805 CDS YP_001725863.1 170020909 6065409 3170250..3170630 1 NC_010468.1 KEGG: sfv:SFV_0587 putative homeobox protein; putative homeobox protein 3170630 6065409 EcolC_2909 Escherichia coli ATCC 8739 putative homeobox protein YP_001725863.1 3170250 D 481805 CDS YP_001725864.1 170020910 6065419 3170744..3171685 1 NC_010468.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 3171685 6065419 EcolC_2910 Escherichia coli ATCC 8739 zinc transporter ZitB YP_001725864.1 3170744 D 481805 CDS YP_001725865.1 170020911 6064996 complement(3171682..3172401) 1 NC_010468.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: ssn:SSON_0703 required for NMN transport; nicotinamide mononucleotide transporter PnuC 3172401 6064996 EcolC_2911 Escherichia coli ATCC 8739 nicotinamide mononucleotide transporter PnuC YP_001725865.1 3171682 R 481805 CDS YP_001725866.1 170020912 6064761 complement(3172439..3173482) 1 NC_010468.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 3173482 6064761 EcolC_2912 Escherichia coli ATCC 8739 quinolinate synthetase YP_001725866.1 3172439 R 481805 CDS YP_001725867.1 170020913 6065469 complement(3174925..3175716) 1 NC_010468.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 3175716 6065469 EcolC_2913 Escherichia coli ATCC 8739 tol-pal system protein YbgF YP_001725867.1 3174925 R 481805 CDS YP_001725868.1 170020914 6065471 complement(3175726..3176247) 1 NC_010468.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: sbo:SBO_0600 peptidoglycan-associated lipoprotein; peptidoglycan-associated outer membrane lipoprotein 3176247 6065471 EcolC_2914 Escherichia coli ATCC 8739 peptidoglycan-associated outer membrane lipoprotein YP_001725868.1 3175726 R 481805 CDS YP_001725869.1 170020915 6065480 complement(3176282..3177574) 1 NC_010468.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 3177574 tolB 6065480 tolB Escherichia coli ATCC 8739 translocation protein TolB YP_001725869.1 3176282 R 481805 CDS YP_001725870.1 170020916 6065482 complement(3177707..3178978) 1 NC_010468.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 3178978 tolA 6065482 tolA Escherichia coli ATCC 8739 cell envelope integrity inner membrane protein TolA YP_001725870.1 3177707 R 481805 CDS YP_001725871.1 170020917 6065485 complement(3179043..3179471) 1 NC_010468.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 3179471 6065485 EcolC_2917 Escherichia coli ATCC 8739 colicin uptake protein TolR YP_001725871.1 3179043 R 481805 CDS YP_001725872.1 170020918 6065492 complement(3179475..3180158) 1 NC_010468.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 3180158 6065492 EcolC_2918 Escherichia coli ATCC 8739 colicin uptake protein TolQ YP_001725872.1 3179475 R 481805 CDS YP_001725873.1 170020919 6065496 complement(3180164..3180568) 1 NC_010468.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 3180568 6065496 EcolC_2919 Escherichia coli ATCC 8739 acyl-CoA thioester hydrolase YbgC YP_001725873.1 3180164 R 481805 CDS YP_001725874.1 170020920 6065499 complement(3180718..3181011) 1 NC_010468.1 TIGRFAM: cyd operon protein YbgE; PFAM: Cyd operon protein YbgE; KEGG: sdy:SDY_0683 hypothetical protein; hypothetical protein 3181011 6065499 EcolC_2920 Escherichia coli ATCC 8739 hypothetical protein YP_001725874.1 3180718 R 481805 CDS YP_001725875.1 170020921 6065506 complement(3181011..3181124) 1 NC_010468.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sdy:SDY_0682 putative outer membrane lipoprotein; cyd operon protein YbgT 3181124 6065506 EcolC_2921 Escherichia coli ATCC 8739 cyd operon protein YbgT YP_001725875.1 3181011 R 481805 CDS YP_001725876.1 170020922 6065507 complement(3181139..3182278) 1 NC_010468.1 KEGG: ssn:SSON_0686 cytochrome d terminal oxidase polypeptide subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 3182278 6065507 EcolC_2922 Escherichia coli ATCC 8739 cytochrome d ubiquinol oxidase subunit II YP_001725876.1 3181139 R 481805 CDS YP_001725877.1 170020923 6065510 complement(3182294..3183862) 1 NC_010468.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sbo:SBO_0592 cytochrome d terminal oxidase, polypeptide subunit I; cytochrome bd ubiquinol oxidase subunit I 3183862 6065510 EcolC_2923 Escherichia coli ATCC 8739 cytochrome bd ubiquinol oxidase subunit I YP_001725877.1 3182294 R 481805 CDS YP_001725878.1 170020924 6065513 complement(3184709..3187342) 1 NC_010468.1 PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; KEGG: sfv:SFV_0604 putative sugar hydrolase; alpha-mannosidase 3187342 6065513 EcolC_2924 Escherichia coli ATCC 8739 alpha-mannosidase YP_001725878.1 3184709 R 481805 CDS YP_001725879.1 170020925 6065515 complement(3187360..3189276) 1 NC_010468.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 3189276 6065515 EcolC_2925 Escherichia coli ATCC 8739 PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC YP_001725879.1 3187360 R 481805 CDS YP_001725880.1 170020926 6065519 3189445..3190167 1 NC_010468.1 regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 3190167 6065519 EcolC_2926 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor MngR YP_001725880.1 3189445 D 481805 CDS YP_001725881.1 170020927 6065521 complement(3190271..3191140) 1 NC_010468.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 3191140 6065521 EcolC_2927 Escherichia coli ATCC 8739 succinyl-CoA synthetase subunit alpha YP_001725881.1 3190271 R 481805 CDS YP_001725882.1 170020928 6065523 complement(3191140..3192306) 1 NC_010468.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 3192306 sucC 6065523 sucC Escherichia coli ATCC 8739 succinyl-CoA synthetase subunit beta YP_001725882.1 3191140 R 481805 CDS YP_001725883.1 170020929 6065524 complement(3192581..3193798) 1 NC_010468.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 3193798 6065524 EcolC_2929 Escherichia coli ATCC 8739 dihydrolipoamide succinyltransferase YP_001725883.1 3192581 R 481805 CDS YP_001725884.1 170020930 6065526 complement(3193813..3196614) 1 NC_010468.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 3196614 sucA 6065526 sucA Escherichia coli ATCC 8739 2-oxoglutarate dehydrogenase E1 component YP_001725884.1 3193813 R 481805 CDS YP_001725885.1 170020931 6065532 complement(3196815..3197531) 1 NC_010468.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 3197531 sdhB 6065532 sdhB Escherichia coli ATCC 8739 succinate dehydrogenase iron-sulfur subunit YP_001725885.1 3196815 R 481805 CDS YP_001725886.1 170020932 6065372 complement(3197547..3199313) 1 NC_010468.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 3199313 sdhA 6065372 sdhA Escherichia coli ATCC 8739 succinate dehydrogenase flavoprotein subunit YP_001725886.1 3197547 R 481805 CDS YP_001725887.1 170020933 6065462 complement(3199313..3199660) 1 NC_010468.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: sdy:SDY_0660 succinate dehydrogenase, hydrophobic subunit; succinate dehydrogenase cytochrome b556 small membrane subunit 3199660 sdhD 6065462 sdhD Escherichia coli ATCC 8739 succinate dehydrogenase cytochrome b556 small membrane subunit YP_001725887.1 3199313 R 481805 CDS YP_001725888.1 170020934 6065538 complement(3199654..3200058) 1 NC_010468.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: sfx:S0589 succinate dehydrogenase, cytochrome b556; succinate dehydrogenase cytochrome b556 large membrane subunit 3200058 sdhC 6065538 sdhC Escherichia coli ATCC 8739 succinate dehydrogenase cytochrome b556 large membrane subunit YP_001725888.1 3199654 R 481805 CDS YP_001725889.1 170020935 6064981 3200752..3202035 1 NC_010468.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 3202035 gltA 6064981 gltA Escherichia coli ATCC 8739 type II citrate synthase YP_001725889.1 3200752 D 481805 CDS YP_001725890.1 170020936 6065546 3202424..3202990 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0670 putative fimbrial-like protein; fimbrial protein 3202990 6065546 EcolC_2936 Escherichia coli ATCC 8739 fimbrial protein YP_001725890.1 3202424 D 481805 CDS YP_001725891.1 170020937 6065552 3203041..3205500 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfx:S0592 putative outer membrane protein; fimbrial biogenesis outer membrane usher protein 3205500 6065552 EcolC_2937 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001725891.1 3203041 D 481805 CDS YP_001725892.1 170020938 6065556 3205515..3206246 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_0668 putative chaperone; pili assembly chaperone 3206246 6065556 EcolC_2938 Escherichia coli ATCC 8739 pili assembly chaperone YP_001725892.1 3205515 D 481805 CDS YP_001725893.1 170020939 6065558 3206243..3207304 1 NC_010468.1 KEGG: ssn:SSON_0667 hypothetical protein; hypothetical protein 3207304 6065558 EcolC_2939 Escherichia coli ATCC 8739 hypothetical protein YP_001725893.1 3206243 D 481805 CDS YP_001725894.1 170020940 6065559 3207456..3208502 1 NC_010468.1 TIGRFAM: membrane protein AbrB duplication; PFAM: putative ammonia monooxygenase; KEGG: ssn:SSON_0666 putative transport protein; membrane protein AbrB 3208502 6065559 EcolC_2940 Escherichia coli ATCC 8739 membrane protein AbrB YP_001725894.1 3207456 D 481805 CDS YP_001725895.1 170020941 6065572 complement(3208499..3209290) 1 NC_010468.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 3209290 6065572 EcolC_2941 Escherichia coli ATCC 8739 endonuclease VIII YP_001725895.1 3208499 R 481805 CDS YP_001725896.1 170020942 6065582 complement(3209326..3210060) 1 NC_010468.1 PFAM: LamB/YcsF family protein; KEGG: sbo:SBO_0572 putative lactam utilization protein; LamB/YcsF family protein 3210060 6065582 EcolC_2942 Escherichia coli ATCC 8739 LamB/YcsF family protein YP_001725896.1 3209326 R 481805 CDS YP_001725897.1 170020943 6065584 complement(3210050..3210982) 1 NC_010468.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: sbo:SBO_0571 putative carboxylase; urea amidolyase-like protein 3210982 6065584 EcolC_2943 Escherichia coli ATCC 8739 urea amidolyase-like protein YP_001725897.1 3210050 R 481805 CDS YP_001725898.1 170020944 6065598 complement(3210976..3211632) 1 NC_010468.1 PFAM: Allophanate hydrolase subunit 1; KEGG: ssn:SSON_0662 putative carboxylase; allophanate hydrolase subunit 1 3211632 6065598 EcolC_2944 Escherichia coli ATCC 8739 allophanate hydrolase subunit 1 YP_001725898.1 3210976 R 481805 CDS YP_001725899.1 170020945 6065600 complement(3211655..3212398) 1 NC_010468.1 PFAM: protein of unknown function DUF34; KEGG: sbo:SBO_0569 hypothetical protein; putative hydrolase-oxidase 3212398 6065600 EcolC_2945 Escherichia coli ATCC 8739 putative hydrolase-oxidase YP_001725899.1 3211655 R 481805 CDS YP_001725900.1 170020946 6065618 3212669..3214150 1 NC_010468.1 KEGG: sfx:S0601 putative transport protein; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; amino acid/peptide transporter 3214150 6065618 EcolC_2946 Escherichia coli ATCC 8739 amino acid/peptide transporter YP_001725900.1 3212669 D 481805 CDS YP_001725901.1 170020947 6065619 complement(3214192..3215610) 1 NC_010468.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 3215610 6065619 EcolC_2947 Escherichia coli ATCC 8739 deoxyribodipyrimidine photolyase YP_001725901.1 3214192 R 481805 CDS YP_001725902.1 170020948 6065627 complement(3215607..3216116) 1 NC_010468.1 PFAM: Protein of unknown function DUF1722; KEGG: sfv:SFV_0628 hypothetical protein; hypothetical protein 3216116 6065627 EcolC_2948 Escherichia coli ATCC 8739 hypothetical protein YP_001725902.1 3215607 R 481805 CDS YP_001725903.1 170020949 6065628 complement(3216264..3217025) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein 3217025 6065628 EcolC_2949 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001725903.1 3216264 R 481805 CDS YP_001725904.1 170020950 6064758 complement(3217156..3218292) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein 3218292 6064758 EcolC_2950 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001725904.1 3217156 R 481805 CDS YP_001725905.1 170020951 6065644 complement(3220082..3220651) 1 NC_010468.1 hypothetical protein 3220651 6065644 EcolC_2952 Escherichia coli ATCC 8739 hypothetical protein YP_001725905.1 3220082 R 481805 CDS YP_001725906.1 170020952 6065650 complement(3220648..3222081) 1 NC_010468.1 PFAM: RHS protein; YD repeat-containing protein; KEGG: ssn:SSON_0655 RhsA protein in rhs element; RHS protein 3222081 6065650 EcolC_2953 Escherichia coli ATCC 8739 RHS protein YP_001725906.1 3220648 R 481805 CDS YP_001725907.1 170020953 6065659 complement(3222199..3222525) 1 NC_010468.1 hypothetical protein 3222525 6065659 EcolC_2954 Escherichia coli ATCC 8739 hypothetical protein YP_001725907.1 3222199 R 481805 CDS YP_001725908.1 170020954 6065660 complement(3222525..3226718) 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 3226718 6065660 EcolC_2955 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001725908.1 3222525 R 481805 CDS YP_001725909.1 170020955 6065664 complement(3226961..3227167) 1 NC_010468.1 KEGG: sdy:SDY_0635 hypothetical protein; hypothetical protein 3227167 6065664 EcolC_2956 Escherichia coli ATCC 8739 hypothetical protein YP_001725909.1 3226961 R 481805 CDS YP_001725910.1 170020956 6065672 3227480..3227569 1 NC_010468.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase F 3227569 kdpF 6065672 kdpF Escherichia coli ATCC 8739 potassium-transporting ATPase F YP_001725910.1 3227480 D 481805 CDS YP_001725911.1 170020957 6065684 3227569..3229242 1 NC_010468.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase A 3229242 6065684 EcolC_2958 Escherichia coli ATCC 8739 potassium-transporting ATPase A YP_001725911.1 3227569 D 481805 CDS YP_001725912.1 170020958 6065688 3229265..3231313 1 NC_010468.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase B 3231313 6065688 EcolC_2959 Escherichia coli ATCC 8739 potassium-transporting ATPase B YP_001725912.1 3229265 D 481805 CDS YP_001725913.1 170020959 6065693 3231322..3231894 1 NC_010468.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase C 3231894 6065693 EcolC_2960 Escherichia coli ATCC 8739 potassium-transporting ATPase C YP_001725913.1 3231322 D 481805 CDS YP_001725914.1 170020960 6065697 3231887..3234574 1 NC_010468.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 3234574 6065697 EcolC_2961 Escherichia coli ATCC 8739 sensor protein KdpD YP_001725914.1 3231887 D 481805 CDS YP_001725915.1 170020961 6065699 3234571..3235248 1 NC_010468.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 3235248 6065699 EcolC_2962 Escherichia coli ATCC 8739 DNA-binding transcriptional activator KdpE YP_001725915.1 3234571 D 481805 CDS YP_001725916.1 170020962 6065700 3235844..3238042 1 NC_010468.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sbo:SBO_0554 ornithine decarboxylase isozyme, inducible; ornithine decarboxylase 3238042 6065700 EcolC_2963 Escherichia coli ATCC 8739 ornithine decarboxylase YP_001725916.1 3235844 D 481805 CDS YP_001725917.1 170020963 6065009 3238039..3239358 1 NC_010468.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 3239358 potE 6065009 potE Escherichia coli ATCC 8739 putrescine transporter YP_001725917.1 3238039 D 481805 CDS YP_001725918.1 170020964 6065718 3239707..3240357 1 NC_010468.1 KEGG: sbo:SBO_0552 hypothetical protein; hypothetical protein 3240357 6065718 EcolC_2966 Escherichia coli ATCC 8739 hypothetical protein YP_001725918.1 3239707 D 481805 CDS YP_001725919.1 170020965 6065719 complement(3240398..3240892) 1 NC_010468.1 KEGG: sbo:SBO_0551 putative pectinase; putative pectinase 3240892 6065719 EcolC_2967 Escherichia coli ATCC 8739 putative pectinase YP_001725919.1 3240398 R 481805 CDS YP_001725920.1 170020966 6065727 complement(3241107..3242747) 1 NC_010468.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 3242747 6065727 EcolC_2968 Escherichia coli ATCC 8739 phosphoglucomutase YP_001725920.1 3241107 R 481805 CDS YP_001725921.1 170020967 6065728 complement(3242773..3243318) 1 NC_010468.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 3243318 6065728 EcolC_2969 Escherichia coli ATCC 8739 replication initiation regulator SeqA YP_001725921.1 3242773 R 481805 CDS YP_001725922.1 170020968 6065735 3243503..3244267 1 NC_010468.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sbo:SBO_0548 hypothetical protein; hypothetical protein 3244267 6065735 EcolC_2970 Escherichia coli ATCC 8739 hypothetical protein YP_001725922.1 3243503 D 481805 CDS YP_001725923.1 170020969 6065736 3244338..3244700 1 NC_010468.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sdy:SDY_0625 hypothetical protein; LexA regulated protein 3244700 6065736 EcolC_2971 Escherichia coli ATCC 8739 LexA regulated protein YP_001725923.1 3244338 D 481805 CDS YP_001725924.1 170020970 6065157 3244840..3245370 1 NC_010468.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 3245370 6065157 EcolC_2972 Escherichia coli ATCC 8739 flavodoxin FldA YP_001725924.1 3244840 D 481805 CDS YP_001725925.1 170020971 6065743 3245659..3246105 1 NC_010468.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 3246105 fur 6065743 fur Escherichia coli ATCC 8739 ferric uptake regulator YP_001725925.1 3245659 D 481805 CDS YP_001725926.1 170020972 6065255 complement(3246189..3246515) 1 NC_010468.1 KEGG: sfl:SF0611 hypothetical protein; hypothetical protein 3246515 6065255 EcolC_2974 Escherichia coli ATCC 8739 hypothetical protein YP_001725926.1 3246189 R 481805 CDS YP_001725927.1 170020973 6065746 complement(3246565..3247971) 1 NC_010468.1 PFAM: outer membrane porin; KEGG: sfx:S0623 hypothetical protein; outer membrane porin 3247971 6065746 EcolC_2975 Escherichia coli ATCC 8739 outer membrane porin YP_001725927.1 3246565 R 481805 CDS YP_001725928.1 170020974 6065680 complement(3248548..3250212) 1 NC_010468.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 3250212 6065680 EcolC_2976 Escherichia coli ATCC 8739 glutaminyl-tRNA synthetase YP_001725928.1 3248548 R 481805 CDS YP_001725929.1 170020975 6065543 complement(3250480..3252426) 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 3252426 6065543 EcolC_2977 Escherichia coli ATCC 8739 PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_001725929.1 3250480 R 481805 CDS YP_001725930.1 170020976 6065756 3252759..3253559 1 NC_010468.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 3253559 nagB 6065756 nagB Escherichia coli ATCC 8739 glucosamine-6-phosphate deaminase YP_001725930.1 3252759 D 481805 CDS YP_001725931.1 170020977 6065340 3253619..3254767 1 NC_010468.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 3254767 nagA 6065340 nagA Escherichia coli ATCC 8739 N-acetylglucosamine-6-phosphate deacetylase YP_001725931.1 3253619 D 481805 CDS YP_001725932.1 170020978 6065762 3254776..3255996 1 NC_010468.1 PFAM: ROK family protein; KEGG: sdy:SDY_0610 transcriptional repressor of N-acetylglucosamine operon; ROK family protein 3255996 6065762 EcolC_2980 Escherichia coli ATCC 8739 ROK family protein YP_001725932.1 3254776 D 481805 CDS YP_001725933.1 170020979 6065533 3256044..3256796 1 NC_010468.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdy:SDY_0609 N-acetylglucosamine metabolism; UMP phosphatase 3256796 6065533 EcolC_2981 Escherichia coli ATCC 8739 UMP phosphatase YP_001725933.1 3256044 D 481805 CDS YP_001725934.1 170020980 6065771 3257193..3258857 1 NC_010468.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 3258857 asnB 6065771 asnB Escherichia coli ATCC 8739 asparagine synthetase B YP_001725934.1 3257193 D 481805 CDS YP_001725935.1 170020981 6065838 complement(3260094..3261269) 1 NC_010468.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 3261269 ubiF 6065838 ubiF Escherichia coli ATCC 8739 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_001725935.1 3260094 R 481805 CDS YP_001725936.1 170020982 6065844 3261415..3262839 1 NC_010468.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 3262839 6065844 EcolC_2984 Escherichia coli ATCC 8739 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001725936.1 3261415 D 481805 CDS YP_001725937.1 170020983 6065846 3262953..3264032 1 NC_010468.1 PFAM: PhoH family protein; KEGG: sdy:SDY_0596 putative ATP-binding protein in pho regulon; PhoH family protein 3264032 6065846 EcolC_2985 Escherichia coli ATCC 8739 PhoH family protein YP_001725937.1 3262953 D 481805 CDS YP_001725938.1 170020984 6064922 3264029..3264496 1 NC_010468.1 PFAM: protein of unknown function UPF0054; KEGG: sbo:SBO_0523 hypothetical protein; putative metalloprotease 3264496 6064922 EcolC_2986 Escherichia coli ATCC 8739 putative metalloprotease YP_001725938.1 3264029 D 481805 CDS YP_001725939.1 170020985 6065848 3264586..3265464 1 NC_010468.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: sdy:SDY_0594 putative transport protein; transporter-associated protein 3265464 6065848 EcolC_2987 Escherichia coli ATCC 8739 transporter-associated protein YP_001725939.1 3264586 D 481805 CDS YP_001725940.1 170020986 6065850 3265489..3267027 1 NC_010468.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 3267027 lnt 6065850 lnt Escherichia coli ATCC 8739 apolipoprotein N-acyltransferase YP_001725940.1 3265489 D 481805 CDS YP_001725941.1 170020987 6065853 complement(3267154..3269031) 1 NC_010468.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: Rhomboid family protein; KEGG: ssn:SSON_0610 hypothetical protein; hypothetical protein 3269031 6065853 EcolC_2989 Escherichia coli ATCC 8739 hypothetical protein YP_001725941.1 3267154 R 481805 CDS YP_001725942.1 170020988 6065875 3269486..3270394 1 NC_010468.1 PFAM: extracellular solute-binding protein family 3; KEGG: sdy:SDY_0592 putative periplasmic binding transport protein; glutamate and aspartate transporter subunit 3270394 6065875 EcolC_2990 Escherichia coli ATCC 8739 glutamate and aspartate transporter subunit YP_001725942.1 3269486 D 481805 CDS YP_001725943.1 170020989 6065881 3270564..3271304 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_0672 glutamate/aspartate transport system permease; polar amino acid ABC transporter inner membrane protein 3271304 6065881 EcolC_2991 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001725943.1 3270564 D 481805 CDS YP_001725944.1 170020990 6065884 3271304..3271978 1 NC_010468.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfx:S0650 glutamate/aspartate transport system permease; polar amino acid ABC transporter inner membrane protein 3271978 6065884 EcolC_2992 Escherichia coli ATCC 8739 polar amino acid ABC transporter inner membrane protein YP_001725944.1 3271304 D 481805 CDS YP_001725945.1 170020991 6065890 3271978..3272703 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_0606 ATP-binding protein of glutamate/aspartate transport system; ABC transporter-like protein 3272703 6065890 EcolC_2993 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001725945.1 3271978 D 481805 CDS YP_001725946.1 170020992 6065891 3272821..3273756 1 NC_010468.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 3273756 rihA 6065891 rihA Escherichia coli ATCC 8739 ribonucleoside hydrolase 1 YP_001725946.1 3272821 D 481805 CDS YP_001725947.1 170020993 6065896 3273840..3275510 1 NC_010468.1 PFAM: Heat shock protein 70; KEGG: ssn:SSON_0604 putative DnaK protein; 2-alkenal reductase 3275510 6065896 EcolC_2995 Escherichia coli ATCC 8739 2-alkenal reductase YP_001725947.1 3273840 D 481805 CDS YP_001725948.1 170020994 6065904 complement(3275570..3277021) 1 NC_010468.1 PFAM: heat shock protein DnaJ domain protein; KEGG: ssn:SSON_0603 hypothetical protein; heat shock protein DnaJ domain-containing protein 3277021 6065904 EcolC_2996 Escherichia coli ATCC 8739 heat shock protein DnaJ domain-containing protein YP_001725948.1 3275570 R 481805 CDS YP_001725949.1 170020995 6065913 complement(3277018..3277725) 1 NC_010468.1 PFAM: protein of unknown function DUF1266; KEGG: sfv:SFV_0678 putative tRNA ligase; hypothetical protein 3277725 6065913 EcolC_2997 Escherichia coli ATCC 8739 hypothetical protein YP_001725949.1 3277018 R 481805 CDS YP_001725950.1 170020996 6065923 3277827..3278381 1 NC_010468.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfv:SFV_0679 hypothetical protein; Sel1 domain-containing protein 3278381 6065923 EcolC_2998 Escherichia coli ATCC 8739 Sel1 domain-containing protein YP_001725950.1 3277827 D 481805 CDS YP_001725951.1 170020997 6065931 complement(3278391..3279818) 1 NC_010468.1 PFAM: heat shock protein DnaJ domain protein; KEGG: sbo:SBO_0510 putative enzyme of polynucleotide modification; heat shock protein DnaJ domain-containing protein 3279818 6065931 EcolC_2999 Escherichia coli ATCC 8739 heat shock protein DnaJ domain-containing protein YP_001725951.1 3278391 R 481805 CDS YP_001725952.1 170020998 6065934 complement(3279815..3280522) 1 NC_010468.1 PFAM: protein of unknown function DUF1266; KEGG: sbo:SBO_0509 hypothetical protein; hypothetical protein 3280522 6065934 EcolC_3000 Escherichia coli ATCC 8739 hypothetical protein YP_001725952.1 3279815 R 481805 CDS YP_001725953.1 170020999 6065940 3280686..3281663 1 NC_010468.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: ssn:SSON_0598 hypothetical protein; Sel1 domain-containing protein 3281663 6065940 EcolC_3001 Escherichia coli ATCC 8739 Sel1 domain-containing protein YP_001725953.1 3280686 D 481805 CDS YP_001725954.1 170021000 6065273 complement(3281733..3282215) 1 NC_010468.1 PFAM: protein of unknown function DUF1451; KEGG: sdy:SDY_0567 putative alpha helical protein; hypothetical protein 3282215 6065273 EcolC_3002 Escherichia coli ATCC 8739 hypothetical protein YP_001725954.1 3281733 R 481805 CDS YP_001725955.1 170021001 6065945 3282451..3285033 1 NC_010468.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 3285033 leuS 6065945 leuS Escherichia coli ATCC 8739 leucyl-tRNA synthetase YP_001725955.1 3282451 D 481805 CDS YP_001725956.1 170021002 6065946 3285048..3285629 1 NC_010468.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 3285629 6065946 EcolC_3004 Escherichia coli ATCC 8739 LPS-assembly lipoprotein RlpB YP_001725956.1 3285048 D 481805 CDS YP_001725957.1 170021003 6065950 3285629..3286660 1 NC_010468.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 3286660 holA 6065950 holA Escherichia coli ATCC 8739 DNA polymerase III subunit delta YP_001725957.1 3285629 D 481805 CDS YP_001725958.1 170021004 6065953 3286662..3287303 1 NC_010468.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 3287303 nadD 6065953 nadD Escherichia coli ATCC 8739 nicotinic acid mononucleotide adenylyltransferase YP_001725958.1 3286662 D 481805 CDS YP_001725959.1 170021005 6065968 3287327..3287938 1 NC_010468.1 TIGRFAM: alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase; KEGG: sfv:SFV_0688 PhpB; alpha-ribazole phosphatase 3287938 6065968 EcolC_3007 Escherichia coli ATCC 8739 alpha-ribazole phosphatase YP_001725959.1 3287327 D 481805 CDS YP_001725960.1 170021006 6065969 3288198..3288515 1 NC_010468.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: sfv:SFV_0689 hypothetical protein; hypothetical protein 3288515 6065969 EcolC_3008 Escherichia coli ATCC 8739 hypothetical protein YP_001725960.1 3288198 D 481805 CDS YP_001725961.1 170021007 6065971 3288519..3288986 1 NC_010468.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 3288986 6065971 EcolC_3009 Escherichia coli ATCC 8739 rRNA large subunit methyltransferase YP_001725961.1 3288519 D 481805 CDS YP_001725962.1 170021008 6065972 3289017..3290918 1 NC_010468.1 KEGG: sfv:SFV_0691 penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; penicillin-binding protein 2 3290918 6065972 EcolC_3010 Escherichia coli ATCC 8739 penicillin-binding protein 2 YP_001725962.1 3289017 D 481805 CDS YP_001725963.1 170021009 6065979 3290921..3292033 1 NC_010468.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: sbo:SBO_0498 rod shape-determining membrane protein; cell wall shape-determining protein 3292033 6065979 EcolC_3011 Escherichia coli ATCC 8739 cell wall shape-determining protein YP_001725963.1 3290921 D 481805 CDS YP_001725964.1 170021010 6065980 3292044..3293132 1 NC_010468.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: ssn:SSON_0587 minor lipoprotein; rare lipoprotein A 3293132 6065980 EcolC_3012 Escherichia coli ATCC 8739 rare lipoprotein A YP_001725964.1 3292044 D 481805 CDS YP_001725965.1 170021011 6065984 3293199..3294482 1 NC_010468.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 3294482 6065984 EcolC_3013 Escherichia coli ATCC 8739 D-alanyl-D-alanine carboxypeptidase YP_001725965.1 3293199 D 481805 CDS YP_001725966.1 170021012 6065985 3294592..3294855 1 NC_010468.1 PFAM: protein of unknown function DUF493; KEGG: sdy:SDY_0553 hypothetical protein; hypothetical protein 3294855 6065985 EcolC_3014 Escherichia coli ATCC 8739 hypothetical protein YP_001725966.1 3294592 D 481805 CDS YP_001725967.1 170021013 6065988 3294956..3295597 1 NC_010468.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 3295597 lipB 6065988 lipB Escherichia coli ATCC 8739 lipoate-protein ligase B YP_001725967.1 3294956 D 481805 CDS YP_001725968.1 170021014 6065991 3295857..3296810 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_0697 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 3296810 6065991 EcolC_3016 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001725968.1 3295857 D 481805 CDS YP_001725969.1 170021015 6065998 3297019..3297984 1 NC_010468.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 3297984 6065998 EcolC_3017 Escherichia coli ATCC 8739 lipoyl synthase YP_001725969.1 3297019 D 481805 CDS YP_001725970.1 170021016 6066000 complement(3298085..3298288) 1 NC_010468.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 3298288 tatE 6066000 tatE Escherichia coli ATCC 8739 twin arginine translocase protein E YP_001725970.1 3298085 R 481805 CDS YP_001725971.1 170021017 6066007 3299297..3299680 1 NC_010468.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 3299680 6066007 EcolC_3020 Escherichia coli ATCC 8739 camphor resistance protein CrcB YP_001725971.1 3299297 D 481805 CDS YP_001725972.1 170021018 6066015 complement(3299734..3299943) 1 NC_010468.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 3299943 cspE 6066015 cspE Escherichia coli ATCC 8739 cold shock protein CspE YP_001725972.1 3299734 R 481805 CDS YP_001725973.1 170021019 6066016 complement(3300118..3300678) 1 NC_010468.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 3300678 pagP 6066016 pagP Escherichia coli ATCC 8739 palmitoyl transferase YP_001725973.1 3300118 R 481805 CDS YP_001725974.1 170021020 6066017 3301267..3302652 1 NC_010468.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 3302652 dcuC 6066017 dcuC Escherichia coli ATCC 8739 C4-dicarboxylate transporter DcuC YP_001725974.1 3301267 D 481805 CDS YP_001725975.1 170021021 6066630 complement(3302693..3303373) 1 NC_010468.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 3303373 dpiA 6066630 dpiA Escherichia coli ATCC 8739 two-component response regulator DpiA YP_001725975.1 3302693 R 481805 CDS YP_001725976.1 170021022 6066019 complement(3303342..3305000) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; KEGG: ssn:SSON_0572 putative sensor-type protein; signal transduction histidine kinase regulating citrate/malate metabolism 3305000 6066019 EcolC_3025 Escherichia coli ATCC 8739 signal transduction histidine kinase regulating citrate/malate metabolism YP_001725976.1 3303342 R 481805 CDS YP_001725977.1 170021023 6066026 3305380..3306438 1 NC_010468.1 KEGG: sbo:SBO_0483 citrate lyase synthetase; TIGRFAM: cytidyltransferase-related domain protein; citrate lyase ligase; PFAM: GCN5-related N-acetyltransferase; Citrate lyase ligase domain protein; citrate lyase ligase 3306438 6066026 EcolC_3026 Escherichia coli ATCC 8739 citrate lyase ligase YP_001725977.1 3305380 D 481805 CDS YP_001725978.1 170021024 6065948 3306453..3306749 1 NC_010468.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 3306749 6065948 EcolC_3027 Escherichia coli ATCC 8739 citrate lyase subunit gamma YP_001725978.1 3306453 D 481805 CDS YP_001725979.1 170021025 6066029 3306746..3307654 1 NC_010468.1 KEGG: sbo:SBO_0481 citrate lyase beta chain, acyl lyase subunit; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase; citrate lyase subunit beta 3307654 6066029 EcolC_3028 Escherichia coli ATCC 8739 citrate lyase subunit beta YP_001725979.1 3306746 D 481805 CDS YP_001725980.1 170021026 6065185 3307665..3309197 1 NC_010468.1 KEGG: ssn:SSON_0567 citrate lyase alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit; citrate lyase subunit alpha 3309197 6065185 EcolC_3029 Escherichia coli ATCC 8739 citrate lyase subunit alpha YP_001725980.1 3307665 D 481805 CDS YP_001725981.1 170021027 6065423 3309201..3309752 1 NC_010468.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 3309752 citX 6065423 citX Escherichia coli ATCC 8739 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_001725981.1 3309201 D 481805 CDS YP_001725982.1 170021028 6066044 3309727..3310605 1 NC_010468.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 3310605 citG 6066044 citG Escherichia coli ATCC 8739 triphosphoribosyl-dephospho-CoA synthase YP_001725982.1 3309727 D 481805 CDS YP_001725983.1 170021029 6066047 3310656..3312119 1 NC_010468.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: sbo:SBO_0477 putative a membrane protein; anion transporter 3312119 6066047 EcolC_3032 Escherichia coli ATCC 8739 anion transporter YP_001725983.1 3310656 D 481805 CDS YP_001725984.1 170021030 6066052 3312215..3313039 1 NC_010468.1 PFAM: ribonuclease T2; KEGG: sfx:S0535 RNase I; ribonuclease I 3313039 6066052 EcolC_3033 Escherichia coli ATCC 8739 ribonuclease I YP_001725984.1 3312215 D 481805 CDS YP_001725985.1 170021031 6066056 3313269..3313679 1 NC_010468.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 3313679 6066056 EcolC_3034 Escherichia coli ATCC 8739 nucleoside diphosphate kinase regulator YP_001725985.1 3313269 D 481805 CDS YP_001725986.1 170021032 6066058 complement(3313910..3315148) 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sbo:SBO_0473 putative oxidoreductase; alcohol dehydrogenase 3315148 6066058 EcolC_3035 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001725986.1 3313910 R 481805 CDS YP_001725987.1 170021033 6065977 3315369..3315797 1 NC_010468.1 PFAM: UspA domain protein; KEGG: sdy:SDY_0542 hypothetical protein; UspA domain-containing protein 3315797 6065977 EcolC_3036 Escherichia coli ATCC 8739 UspA domain-containing protein YP_001725987.1 3315369 D 481805 CDS YP_001725988.1 170021034 6066060 complement(3315918..3317513) 1 NC_010468.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbo:SBO_0471 alkyl hydroperoxide reductase, F52a subunit; alkyl hydroperoxide reductase subunit F 3317513 6066060 EcolC_3037 Escherichia coli ATCC 8739 alkyl hydroperoxide reductase subunit F YP_001725988.1 3315918 R 481805 CDS YP_001725989.1 170021035 6066068 complement(3317728..3318291) 1 NC_010468.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 3318291 6066068 EcolC_3038 Escherichia coli ATCC 8739 alkyl hydroperoxide reductase subunit C YP_001725989.1 3317728 R 481805 CDS YP_001725990.1 170021036 6066069 3318663..3319409 1 NC_010468.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 3319409 dsbG 6066069 dsbG Escherichia coli ATCC 8739 disulfide isomerase/thiol-disulfide oxidase YP_001725990.1 3318663 D 481805 CDS YP_001725991.1 170021037 6066073 3319618..3320520 1 NC_010468.1 PFAM: regulatory protein LysR; KEGG: sfv:SFV_0557 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 3320520 6066073 EcolC_3040 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001725991.1 3319618 D 481805 CDS YP_001725992.1 170021038 6066080 3320667..3321887 1 NC_010468.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: cko:CKO_02557 hypothetical protein; phosphoadenosine phosphosulfate reductase 3321887 6066080 EcolC_3041 Escherichia coli ATCC 8739 phosphoadenosine phosphosulfate reductase YP_001725992.1 3320667 D 481805 CDS YP_001725993.1 170021039 6066083 3321872..3322489 1 NC_010468.1 PFAM: ParB domain protein nuclease; KEGG: ssn:SSON_0553 hypothetical protein; nuclease 3322489 6066083 EcolC_3042 Escherichia coli ATCC 8739 nuclease YP_001725993.1 3321872 D 481805 CDS YP_001725994.1 170021040 6065622 complement(3322490..3323650) 1 NC_010468.1 catalyzes the transfer of an amino moiety; putative aminotransferase 3323650 6065622 EcolC_3043 Escherichia coli ATCC 8739 putative aminotransferase YP_001725994.1 3322490 R 481805 CDS YP_001725995.1 170021041 6065944 3323759..3324847 1 NC_010468.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 3324847 6065944 EcolC_3044 Escherichia coli ATCC 8739 hypothetical protein YP_001725995.1 3323759 D 481805 CDS YP_001725996.1 170021042 6066089 complement(3324857..3325054) 1 NC_010468.1 PFAM: protein of unknown function DUF466; KEGG: sdy:SDY_0530 hypothetical protein; hypothetical protein 3325054 6066089 EcolC_3045 Escherichia coli ATCC 8739 hypothetical protein YP_001725996.1 3324857 R 481805 CDS YP_001725997.1 170021043 6066092 complement(3325237..3327342) 1 NC_010468.1 PFAM: carbon starvation protein CstA; KEGG: sbo:SBO_0459 carbon starvation protein; carbon starvation protein CstA 3327342 6066092 EcolC_3046 Escherichia coli ATCC 8739 carbon starvation protein CstA YP_001725997.1 3325237 R 481805 CDS YP_001725998.1 170021044 6066097 complement(3327523..3327936) 1 NC_010468.1 PFAM: thioesterase superfamily protein; KEGG: sdy:SDY_0528 hypothetical protein; hypothetical protein 3327936 6066097 EcolC_3047 Escherichia coli ATCC 8739 hypothetical protein YP_001725998.1 3327523 R 481805 CDS YP_001725999.1 170021045 6066110 complement(3327939..3328685) 1 NC_010468.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 3328685 6066110 EcolC_3048 Escherichia coli ATCC 8739 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_001725999.1 3327939 R 481805 CDS YP_001726000.1 170021046 6066116 complement(3328685..3329542) 1 NC_010468.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: sfl:SF0509 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; isochorismatase 3329542 6066116 EcolC_3049 Escherichia coli ATCC 8739 isochorismatase YP_001726000.1 3328685 R 481805 CDS YP_001726001.1 170021047 6066118 complement(3329556..3331166) 1 NC_010468.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 3331166 entE 6066118 entE Escherichia coli ATCC 8739 enterobactin synthase subunit E YP_001726001.1 3329556 R 481805 CDS YP_001726002.1 170021048 6066120 complement(3331176..3332351) 1 NC_010468.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: sdy:SDY_0524 isochorismate hydroxymutase 2; isochorismate synthase 3332351 6066120 EcolC_3051 Escherichia coli ATCC 8739 isochorismate synthase YP_001726002.1 3331176 R 481805 CDS YP_001726003.1 170021049 6066124 3332726..3333682 1 NC_010468.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 3333682 6066124 EcolC_3052 Escherichia coli ATCC 8739 iron-enterobactin transporter periplasmic binding protein YP_001726003.1 3332726 D 481805 CDS YP_001726004.1 170021050 6066134 complement(3333686..3334936) 1 NC_010468.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 3334936 6066134 EcolC_3053 Escherichia coli ATCC 8739 enterobactin exporter EntS YP_001726004.1 3333686 R 481805 CDS YP_001726005.1 170021051 6065761 3335047..3336051 1 NC_010468.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 3336051 6065761 EcolC_3054 Escherichia coli ATCC 8739 iron-enterobactin transporter membrane protein YP_001726005.1 3335047 D 481805 CDS YP_001726006.1 170021052 6066140 3336048..3337040 1 NC_010468.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 3337040 6066140 EcolC_3055 Escherichia coli ATCC 8739 iron-enterobactin transporter permease YP_001726006.1 3336048 D 481805 CDS YP_001726007.1 170021053 6066142 3337037..3337852 1 NC_010468.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 3337852 6066142 EcolC_3056 Escherichia coli ATCC 8739 iron-enterobactin transporter ATP-binding protein YP_001726007.1 3337037 D 481805 CDS YP_001726008.1 170021054 6064678 complement(3337849..3338982) 1 NC_010468.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 3338982 6064678 EcolC_3057 Escherichia coli ATCC 8739 ferric enterobactin transport protein FepE YP_001726008.1 3337849 R 481805 CDS YP_001726009.1 170021055 6066145 complement(3339198..3343079) 1 NC_010468.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 3343079 entF 6066145 entF Escherichia coli ATCC 8739 enterobactin synthase subunit F YP_001726009.1 3339198 R 481805 CDS YP_001726010.1 170021056 6066150 complement(3343076..3343294) 1 NC_010468.1 PFAM: MbtH domain protein; KEGG: sbo:SBO_0446 putative cytoplasmic protein; MbtH domain-containing protein 3343294 6066150 EcolC_3059 Escherichia coli ATCC 8739 MbtH domain-containing protein YP_001726010.1 3343076 R 481805 CDS YP_001726011.1 170021057 6066152 complement(3343297..3344499) 1 NC_010468.1 PFAM: putative esterase; KEGG: sfv:SFV_0530 enterochelin esterase; enterobactin/ferric enterobactin esterase 3344499 6066152 EcolC_3060 Escherichia coli ATCC 8739 enterobactin/ferric enterobactin esterase YP_001726011.1 3343297 R 481805 CDS YP_001726012.1 170021058 6066153 3344742..3346982 1 NC_010468.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 3346982 6066153 EcolC_3061 Escherichia coli ATCC 8739 outer membrane receptor FepA YP_001726012.1 3344742 D 481805 CDS YP_001726013.1 170021059 6066155 3347148..3347777 1 NC_010468.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: ssn:SSON_0533 enterochelin synthetase, component D; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 3347777 6066155 EcolC_3062 Escherichia coli ATCC 8739 enterobactin synthase multienzyme complex phosphopantetheinyltransferase YP_001726013.1 3347148 D 481805 CDS YP_001726014.1 170021060 6065336 complement(3348059..3349171) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein 3349171 6065336 EcolC_3063 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001726014.1 3348059 R 481805 CDS YP_001726015.1 170021061 6066158 complement(3349248..3349400) 1 NC_010468.1 PFAM: Hok/gef cell toxic protein; KEGG: sfx:S0500 hypothetical protein; Hok/gef cell toxic protein 3349400 6066158 EcolC_3064 Escherichia coli ATCC 8739 Hok/gef cell toxic protein YP_001726015.1 3349248 R 481805 CDS YP_001726016.1 170021062 6066162 3349853..3350971 1 NC_010468.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 3350971 6066162 EcolC_3065 Escherichia coli ATCC 8739 carboxylate-amine ligase YP_001726016.1 3349853 D 481805 CDS YP_001726017.1 170021063 6066163 3351037..3351285 1 NC_010468.1 PFAM: protein of unknown function DUF1158; KEGG: sbo:SBO_0441 hypothetical protein; hypothetical protein 3351285 6066163 EcolC_3066 Escherichia coli ATCC 8739 hypothetical protein YP_001726017.1 3351037 D 481805 CDS YP_001726018.1 170021064 6066164 3351350..3351718 1 NC_010468.1 PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_0492 hypothetical protein; hypothetical protein 3351718 6066164 EcolC_3067 Escherichia coli ATCC 8739 hypothetical protein YP_001726018.1 3351350 D 481805 CDS YP_001726019.1 170021065 6066167 3351812..3352465 1 NC_010468.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 3352465 6066167 EcolC_3068 Escherichia coli ATCC 8739 dihydropteridine reductase YP_001726019.1 3351812 D 481805 CDS YP_001726020.1 170021066 6065453 3352573..3353820 1 NC_010468.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0528 putative transport; mechanosensitive ion channel MscS 3353820 6065453 EcolC_3069 Escherichia coli ATCC 8739 mechanosensitive ion channel MscS YP_001726020.1 3352573 D 481805 CDS YP_001726021.1 170021067 6066169 complement(3353888..3355300) 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sfv:SFV_0516 phenylalanine-specific transport system; phenylalanine transporter 3355300 6066169 EcolC_3070 Escherichia coli ATCC 8739 phenylalanine transporter YP_001726021.1 3353888 R 481805 CDS YP_001726022.1 170021068 6066171 complement(3355366..3358509) 1 NC_010468.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: ssn:SSON_0526 putative inner membrane component for iron transport; CzcA family heavy metal efflux protein 3358509 6066171 EcolC_3071 Escherichia coli ATCC 8739 CzcA family heavy metal efflux protein YP_001726022.1 3355366 R 481805 CDS YP_001726023.1 170021069 6066175 complement(3358521..3359744) 1 NC_010468.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 3359744 6066175 EcolC_3072 Escherichia coli ATCC 8739 copper/silver efflux system membrane fusion protein CusB YP_001726023.1 3358521 R 481805 CDS YP_001726024.1 170021070 6066176 complement(3359760..3360092) 1 NC_010468.1 KEGG: sfv:SFV_0506 hypothetical protein; copper-binding protein 3360092 6066176 EcolC_3073 Escherichia coli ATCC 8739 copper-binding protein YP_001726024.1 3359760 R 481805 CDS YP_001726025.1 170021071 6064676 complement(3360250..3361623) 1 NC_010468.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 3361623 6064676 EcolC_3074 Escherichia coli ATCC 8739 copper/silver efflux system outer membrane protein CusC YP_001726025.1 3360250 R 481805 CDS YP_001726026.1 170021072 6066179 3361780..3362463 1 NC_010468.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 3362463 6066179 EcolC_3075 Escherichia coli ATCC 8739 DNA-binding transcriptional activator CusR YP_001726026.1 3361780 D 481805 CDS YP_001726027.1 170021073 6066181 3362453..3363901 1 NC_010468.1 KEGG: ssn:SSON_0521 putative 2-component sensor protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; sensor kinase CusS 3363901 6066181 EcolC_3076 Escherichia coli ATCC 8739 sensor kinase CusS YP_001726027.1 3362453 D 481805 CDS YP_001726028.1 170021074 6066183 3364638..3366539 1 NC_010468.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ssn:SSON_0520 putative Vgr protein; ImpA family type VI secretion-associated protein 3366539 6066183 EcolC_3077 Escherichia coli ATCC 8739 ImpA family type VI secretion-associated protein YP_001726028.1 3364638 D 481805 CDS YP_001726029.1 170021075 6066187 3366567..3367028 1 NC_010468.1 PFAM: Domain of unknown function DUF1795; KEGG: ssn:SSON_0519 hypothetical protein; hypothetical protein 3367028 6066187 EcolC_3078 Escherichia coli ATCC 8739 hypothetical protein YP_001726029.1 3366567 D 481805 CDS YP_001726030.1 170021076 6066190 3367048..3371565 1 NC_010468.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; PAAR repeat-containing protein; KEGG: ssn:SSON_0517 rhs core protein with extension; YD repeat-containing protein 3371565 6066190 EcolC_3079 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001726030.1 3367048 D 481805 CDS YP_001726031.1 170021077 6066197 3371598..3371858 1 NC_010468.1 hypothetical protein 3371858 6066197 EcolC_3080 Escherichia coli ATCC 8739 hypothetical protein YP_001726031.1 3371598 D 481805 CDS YP_001726032.1 170021078 6066198 3371858..3372145 1 NC_010468.1 hypothetical protein 3372145 6066198 EcolC_3081 Escherichia coli ATCC 8739 hypothetical protein YP_001726032.1 3371858 D 481805 CDS YP_001726033.1 170021079 6066203 3373110..3374246 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein 3374246 6066203 EcolC_3082 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001726033.1 3373110 D 481805 CDS YP_001726034.1 170021080 6066206 3374517..3376754 1 NC_010468.1 PFAM: General secretory system II protein E domain protein; KEGG: sfl:SF0470 bacteriophage N4 receptor, outer membrane protein; bacteriophage N4 adsorption protein B 3376754 nfrB 6066206 nfrB Escherichia coli ATCC 8739 bacteriophage N4 adsorption protein B YP_001726034.1 3374517 D 481805 CDS YP_001726035.1 170021081 6066207 3376741..3379713 1 NC_010468.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ssn:SSON_0514 bacteriophage N4 receptor, outer membrane protein; bacteriophage N4 receptor, outer membrane subunit 3379713 6066207 EcolC_3084 Escherichia coli ATCC 8739 bacteriophage N4 receptor, outer membrane subunit YP_001726035.1 3376741 D 481805 CDS YP_001726036.1 170021082 6065757 3379714..3380604 1 NC_010468.1 KEGG: ssn:SSON_0513 hypothetical protein; hypothetical protein 3380604 6065757 EcolC_3085 Escherichia coli ATCC 8739 hypothetical protein YP_001726036.1 3379714 D 481805 CDS YP_001726037.1 170021083 6066218 3380787..3381548 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_0512 envelope protein; AraC family transcriptional regulator 3381548 6066218 EcolC_3086 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726037.1 3380787 D 481805 CDS YP_001726038.1 170021084 6066228 3381913..3382545 1 NC_010468.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 3382545 6066228 EcolC_3087 Escherichia coli ATCC 8739 transcriptional regulator FimZ YP_001726038.1 3381913 D 481805 CDS YP_001726039.1 170021085 6066229 complement(3382548..3383063) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0507 putative fimbrial-like protein; putative fimbrial protein 3383063 6066229 EcolC_3088 Escherichia coli ATCC 8739 putative fimbrial protein YP_001726039.1 3382548 R 481805 CDS YP_001726040.1 170021086 6066234 complement(3383074..3384081) 1 NC_010468.1 KEGG: ssn:SSON_0506 involved in fimbrial asembly; fimbrial asembly protein 3384081 6066234 EcolC_3089 Escherichia coli ATCC 8739 fimbrial asembly protein YP_001726040.1 3383074 R 481805 CDS YP_001726041.1 170021087 6066236 complement(3384094..3386703) 1 NC_010468.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: cko:CKO_02625 hypothetical protein; fimbrial biogenesis outer membrane usher protein 3386703 6066236 EcolC_3090 Escherichia coli ATCC 8739 fimbrial biogenesis outer membrane usher protein YP_001726041.1 3384094 R 481805 CDS YP_001726042.1 170021088 6066238 complement(3386734..3387426) 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: sfx:S0470 putative chaperone; pili assembly chaperone 3387426 6066238 EcolC_3091 Escherichia coli ATCC 8739 pili assembly chaperone YP_001726042.1 3386734 R 481805 CDS YP_001726043.1 170021089 6066239 complement(3387646..3388188) 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: sfx:S0469 putative fimbrial-like protein; fimbrial protein 3388188 6066239 EcolC_3092 Escherichia coli ATCC 8739 fimbrial protein YP_001726043.1 3387646 R 481805 CDS YP_001726044.1 170021090 6066241 3388659..3389525 1 NC_010468.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3389525 6066241 EcolC_3093 Escherichia coli ATCC 8739 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001726044.1 3388659 D 481805 CDS YP_001726045.1 170021091 6066244 3389527..3389739 1 NC_010468.1 KEGG: sdy:SDY_0280 hypothetical protein; hypothetical protein 3389739 6066244 EcolC_3094 Escherichia coli ATCC 8739 hypothetical protein YP_001726045.1 3389527 D 481805 CDS YP_001726046.1 170021092 6066246 3389847..3390368 1 NC_010468.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: sbo:SBO_0416 hypothetical protein; membrane-bound metal-dependent hydrolase 3390368 6066246 EcolC_3095 Escherichia coli ATCC 8739 membrane-bound metal-dependent hydrolase YP_001726046.1 3389847 D 481805 CDS YP_001726047.1 170021093 6066247 complement(3390404..3391789) 1 NC_010468.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 3391789 cysS 6066247 cysS Escherichia coli ATCC 8739 cysteinyl-tRNA synthetase YP_001726047.1 3390404 R 481805 CDS YP_001726048.1 170021094 6066250 3391963..3392457 1 NC_010468.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sfv:SFV_0483 peptidyl-prolyl cis-trans isomerase B (rotamase B); peptidyl-prolyl cis-trans isomerase B 3392457 6066250 EcolC_3097 Escherichia coli ATCC 8739 peptidyl-prolyl cis-trans isomerase B YP_001726048.1 3391963 D 481805 CDS YP_001726049.1 170021095 6066253 3392460..3393182 1 NC_010468.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 3393182 6066253 EcolC_3098 Escherichia coli ATCC 8739 UDP-2,3-diacylglucosamine hydrolase YP_001726049.1 3392460 D 481805 CDS YP_001726050.1 170021096 6066256 3393300..3393809 1 NC_010468.1 KEGG: sbo:SBO_0420 phosphoribosylaminoimidazole carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase catalytic subunit 3393809 6066256 EcolC_3099 Escherichia coli ATCC 8739 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001726050.1 3393300 D 481805 CDS YP_001726051.1 170021097 6066260 3393806..3394873 1 NC_010468.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase 3394873 6066260 EcolC_3100 Escherichia coli ATCC 8739 phosphoribosylaminoimidazole carboxylase ATPase YP_001726051.1 3393806 D 481805 CDS YP_001726052.1 170021098 6064861 complement(3395012..3395905) 1 NC_010468.1 KEGG: ssn:SSON_0497 putative carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; carbamate kinase 3395905 6064861 EcolC_3101 Escherichia coli ATCC 8739 carbamate kinase YP_001726052.1 3395012 R 481805 CDS YP_001726053.1 170021099 6066271 complement(3395902..3396717) 1 NC_010468.1 KEGG: sbo:SBO_0423 putative carboxylase; putative carboxylase 3396717 6066271 EcolC_3102 Escherichia coli ATCC 8739 putative carboxylase YP_001726053.1 3395902 R 481805 CDS YP_001726054.1 170021100 6065218 complement(3396728..3397987) 1 NC_010468.1 PFAM: protein of unknown function DUF1116; KEGG: stm:STM0530 putative cytoplasmic protein; hypothetical protein 3397987 6065218 EcolC_3103 Escherichia coli ATCC 8739 hypothetical protein YP_001726054.1 3396728 R 481805 CDS YP_001726055.1 170021101 6066282 complement(3397997..3399664) 1 NC_010468.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 3399664 6066282 EcolC_3104 Escherichia coli ATCC 8739 membrane protein FdrA YP_001726055.1 3397997 R 481805 CDS YP_001726056.1 170021102 6066283 3399981..3401030 1 NC_010468.1 TIGRFAM: ureidoglycolate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; KEGG: stm:STM0528 ureidoglycolate dehydrogenase; ureidoglycolate dehydrogenase 3401030 6066283 EcolC_3105 Escherichia coli ATCC 8739 ureidoglycolate dehydrogenase YP_001726056.1 3399981 D 481805 CDS YP_001726057.1 170021103 6066292 complement(3402105..3403085) 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: sao:SAOUHSC_00778 hypothetical protein; transposase IS4 family protein 3403085 6066292 EcolC_3107 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001726057.1 3402105 R 481805 CDS YP_001726058.1 170021104 6064859 3403497..3404282 1 NC_010468.1 TIGRFAM: allantoin catabolism protein; PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein; KEGG: sec:SC0565 putative glyoxylate utilization; hypothetical protein 3404282 6064859 EcolC_3108 Escherichia coli ATCC 8739 hypothetical protein YP_001726058.1 3403497 D 481805 CDS YP_001726059.1 170021105 6066298 complement(3404510..3405655) 1 NC_010468.1 PFAM: glycerate kinase; KEGG: stm:STM0525 glycerate kinase II; glycerate kinase 3405655 6066298 EcolC_3109 Escherichia coli ATCC 8739 glycerate kinase YP_001726059.1 3404510 R 481805 CDS YP_001726060.1 170021106 6066312 complement(3405677..3406978) 1 NC_010468.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: spt:SPA2199 putative permease protein; putative purine permease YbbY 3406978 6066312 EcolC_3110 Escherichia coli ATCC 8739 putative purine permease YbbY YP_001726060.1 3405677 R 481805 CDS YP_001726061.1 170021107 6066317 complement(3407035..3408396) 1 NC_010468.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 3408396 6066317 EcolC_3111 Escherichia coli ATCC 8739 allantoinase YP_001726061.1 3407035 R 481805 CDS YP_001726062.1 170021108 6066326 complement(3408456..3409910) 1 NC_010468.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sec:SC0561 putative allantoin permease; allantoin permease 3409910 6066326 EcolC_3112 Escherichia coli ATCC 8739 allantoin permease YP_001726062.1 3408456 R 481805 CDS YP_001726063.1 170021109 6066328 complement(3410079..3410957) 1 NC_010468.1 KEGG: stm:STM0519 tartronic semialdehyde reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 2-hydroxy-3-oxopropionate reductase 3410957 6066328 EcolC_3113 Escherichia coli ATCC 8739 2-hydroxy-3-oxopropionate reductase YP_001726063.1 3410079 R 481805 CDS YP_001726064.1 170021110 6066330 complement(3411057..3411833) 1 NC_010468.1 KEGG: ssn:SSON_0503 glyoxylate-induced protein; TIGRFAM: hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; hydroxypyruvate isomerase 3411833 6066330 EcolC_3114 Escherichia coli ATCC 8739 hydroxypyruvate isomerase YP_001726064.1 3411057 R 481805 CDS YP_001726065.1 170021111 6066333 complement(3411846..3413627) 1 NC_010468.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 3413627 6066333 EcolC_3115 Escherichia coli ATCC 8739 glyoxylate carboligase YP_001726065.1 3411846 R 481805 CDS YP_001726066.1 170021112 6066337 complement(3413717..3414532) 1 NC_010468.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 3414532 6066337 EcolC_3116 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor AllR YP_001726066.1 3413717 R 481805 CDS YP_001726067.1 170021113 6066340 complement(3414610..3415092) 1 NC_010468.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 3415092 6066340 EcolC_3117 Escherichia coli ATCC 8739 ureidoglycolate hydrolase YP_001726067.1 3414610 R 481805 CDS YP_001726068.1 170021114 6066343 3415322..3416248 1 NC_010468.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 3416248 6066343 EcolC_3118 Escherichia coli ATCC 8739 DNA-binding transcriptional activator AllS YP_001726068.1 3415322 D 481805 CDS YP_001726069.1 170021115 6065052 3416317..3417411 1 NC_010468.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 3417411 6065052 EcolC_3119 Escherichia coli ATCC 8739 tRNA 2-selenouridine synthase YP_001726069.1 3416317 D 481805 CDS YP_001726070.1 170021116 6065057 complement(3418124..3420538) 1 NC_010468.1 PFAM: protein of unknown function DUF214; KEGG: ssn:SSON_0485 putative oxidoreductase; hypothetical protein 3420538 6065057 EcolC_3120 Escherichia coli ATCC 8739 hypothetical protein YP_001726070.1 3418124 R 481805 CDS YP_001726071.1 170021117 6064631 complement(3420535..3421221) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0396 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein YbbA 3421221 6064631 EcolC_3121 Escherichia coli ATCC 8739 putative ABC transporter ATP-binding protein YbbA YP_001726071.1 3420535 R 481805 CDS YP_001726072.1 170021118 6066354 3421222..3421815 1 NC_010468.1 PFAM: lipolytic protein G-D-S-L family; KEGG: ssn:SSON_0484 acyl-CoA thioesterase I; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 3421815 6066354 EcolC_3122 Escherichia coli ATCC 8739 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_001726072.1 3421222 D 481805 CDS YP_001726073.1 170021119 6066357 3421844..3422614 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbo:SBO_0395 putative oxidoreductase; short chain dehydrogenase 3422614 6066357 EcolC_3123 Escherichia coli ATCC 8739 short chain dehydrogenase YP_001726073.1 3421844 D 481805 CDS YP_001726074.1 170021120 6066363 3422675..3423529 1 NC_010468.1 PFAM: Thioredoxin domain; KEGG: sdy:SDY_0407 putative thioredoxin-like protein; thioredoxin domain-containing protein 3423529 6066363 EcolC_3124 Escherichia coli ATCC 8739 thioredoxin domain-containing protein YP_001726074.1 3422675 D 481805 CDS YP_001726075.1 170021121 6066372 complement(3423592..3424371) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_0480 putative metal resistance protein; hypothetical protein 3424371 6066372 EcolC_3125 Escherichia coli ATCC 8739 hypothetical protein YP_001726075.1 3423592 R 481805 CDS YP_001726076.1 170021122 6066373 complement(3424358..3425035) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0392 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein YbbL 3425035 6066373 EcolC_3126 Escherichia coli ATCC 8739 putative ABC transporter ATP-binding protein YbbL YP_001726076.1 3424358 R 481805 CDS YP_001726077.1 170021123 6066384 3425181..3426098 1 NC_010468.1 PFAM: band 7 protein; KEGG: sbo:SBO_0391 putative protease; hypothetical protein 3426098 6066384 EcolC_3127 Escherichia coli ATCC 8739 hypothetical protein YP_001726077.1 3425181 D 481805 CDS YP_001726078.1 170021124 6066388 3426095..3426553 1 NC_010468.1 PFAM: protein of unknown function DUF107; KEGG: sbo:SBO_0390 hypothetical protein; hypothetical protein 3426553 6066388 EcolC_3128 Escherichia coli ATCC 8739 hypothetical protein YP_001726078.1 3426095 D 481805 CDS YP_001726079.1 170021125 6066390 complement(3426554..3426961) 1 NC_010468.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 3426961 6066390 EcolC_3129 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator CueR YP_001726079.1 3426554 R 481805 CDS YP_001726080.1 170021126 6066391 complement(3427086..3428378) 1 NC_010468.1 PFAM: Spore germination protein; amino acid permease-associated region; KEGG: ssn:SSON_0475 putative amino acid/amine transport protein; amino acid permease-associated protein 3428378 6066391 EcolC_3130 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001726080.1 3427086 R 481805 CDS YP_001726081.1 170021127 6065800 complement(3428381..3429313) 1 NC_010468.1 catalyzes the formation of glutamate from glutamine; glutaminase 3429313 6065800 EcolC_3131 Escherichia coli ATCC 8739 glutaminase YP_001726081.1 3428381 R 481805 CDS YP_001726082.1 170021128 6066393 3429575..3432079 1 NC_010468.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sbo:SBO_0386 putative ATPase; copper exporting ATPase 3432079 copA 6066393 copA Escherichia coli ATCC 8739 copper exporting ATPase YP_001726082.1 3429575 D 481805 CDS YP_001726083.1 170021129 6065302 complement(3433001..3433396) 1 NC_010468.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sbo:SBO_0385 hypothetical protein; XRE family plasmid maintenance system antidote protein 3433396 6065302 EcolC_3133 Escherichia coli ATCC 8739 XRE family plasmid maintenance system antidote protein YP_001726083.1 3433001 R 481805 CDS YP_001726084.1 170021130 6066401 3433480..3434274 1 NC_010468.1 PFAM: GumN family protein; KEGG: sfv:SFV_0455 putative ligase; GumN family protein 3434274 6066401 EcolC_3134 Escherichia coli ATCC 8739 GumN family protein YP_001726084.1 3433480 D 481805 CDS YP_001726085.1 170021131 6066406 3434478..3434957 1 NC_010468.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sfv:SFV_0454 hypothetical protein; hypothetical protein 3434957 6066406 EcolC_3135 Escherichia coli ATCC 8739 hypothetical protein YP_001726085.1 3434478 D 481805 CDS YP_001726086.1 170021132 6066411 complement(3434994..3436646) 1 NC_010468.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 3436646 ushA 6066411 ushA Escherichia coli ATCC 8739 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_001726086.1 3434994 R 481805 CDS YP_001726087.1 170021133 6066412 3436864..3438084 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0431 fosmidomycin resistance protein; major facilitator transporter 3438084 6066412 EcolC_3137 Escherichia coli ATCC 8739 major facilitator transporter YP_001726087.1 3436864 D 481805 CDS YP_001726088.1 170021134 6066417 3438322..3439998 1 NC_010468.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein 3439998 6066417 EcolC_3138 Escherichia coli ATCC 8739 putative cation:proton antiport protein YP_001726088.1 3438322 D 481805 CDS YP_001726089.1 170021135 6066418 complement(3440131..3441435) 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_0377 inosine-guanosine kinase; inosine kinase 3441435 6066418 EcolC_3139 Escherichia coli ATCC 8739 inosine kinase YP_001726089.1 3440131 R 481805 CDS YP_001726090.1 170021136 6065328 3441587..3442546 1 NC_010468.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ssn:SSON_0463 putative lipase; acetyl esterase 3442546 6065328 EcolC_3140 Escherichia coli ATCC 8739 acetyl esterase YP_001726090.1 3441587 D 481805 CDS YP_001726091.1 170021137 6066432 complement(3442543..3443505) 1 NC_010468.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 3443505 hemH 6066432 hemH Escherichia coli ATCC 8739 ferrochelatase YP_001726091.1 3442543 R 481805 CDS YP_001726092.1 170021138 6066449 complement(3443741..3444385) 1 NC_010468.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 3444385 adk 6066449 adk Escherichia coli ATCC 8739 adenylate kinase YP_001726092.1 3443741 R 481805 CDS YP_001726093.1 170021139 6065841 complement(3444566..3446440) 1 NC_010468.1 molecular chaperone; heat shock protein 90 3446440 6065841 EcolC_3143 Escherichia coli ATCC 8739 heat shock protein 90 YP_001726093.1 3444566 R 481805 CDS YP_001726094.1 170021140 6066466 complement(3446550..3447155) 1 NC_010468.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 3447155 recR 6066466 recR Escherichia coli ATCC 8739 recombination protein RecR YP_001726094.1 3446550 R 481805 CDS YP_001726095.1 170021141 6066467 complement(3447155..3447484) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_0448 hypothetical protein; hypothetical protein 3447484 6066467 EcolC_3145 Escherichia coli ATCC 8739 hypothetical protein YP_001726095.1 3447155 R 481805 CDS YP_001726096.1 170021142 6066293 complement(3447537..3449468) 1 NC_010468.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 3449468 6066293 EcolC_3146 Escherichia coli ATCC 8739 DNA polymerase III subunits gamma and tau YP_001726096.1 3447537 R 481805 CDS YP_001726097.1 170021143 6066468 complement(3449597..3450148) 1 NC_010468.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 3450148 6066468 EcolC_3147 Escherichia coli ATCC 8739 adenine phosphoribosyltransferase YP_001726097.1 3449597 R 481805 CDS YP_001726098.1 170021144 6066472 complement(3450301..3450678) 1 NC_010468.1 PFAM: protein of unknown function DUF454; KEGG: sdy:SDY_0451 putative gene 58; hypothetical protein 3450678 6066472 EcolC_3148 Escherichia coli ATCC 8739 hypothetical protein YP_001726098.1 3450301 R 481805 CDS YP_001726099.1 170021145 6066475 3450748..3451275 1 NC_010468.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 3451275 6066475 EcolC_3149 Escherichia coli ATCC 8739 primosomal replication protein N'' YP_001726099.1 3450748 D 481805 CDS YP_001726100.1 170021146 6066480 3451289..3451450 1 NC_010468.1 KEGG: sbo:SBO_0366 hypothetical protein; hypothetical protein 3451450 6066480 EcolC_3150 Escherichia coli ATCC 8739 hypothetical protein YP_001726100.1 3451289 D 481805 CDS YP_001726101.1 170021147 6066481 complement(3451662..3455024) 1 NC_010468.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 3455024 6066481 EcolC_3151 Escherichia coli ATCC 8739 potassium efflux protein KefA YP_001726101.1 3451662 R 481805 CDS YP_001726102.1 170021148 6066483 complement(3455152..3455799) 1 NC_010468.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 3455799 6066483 EcolC_3152 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor AcrR YP_001726102.1 3455152 R 481805 CDS YP_001726103.1 170021149 6066485 3455941..3457134 1 NC_010468.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_0450 acridine efflux pump; RND family efflux transporter MFP subunit 3457134 6066485 EcolC_3153 Escherichia coli ATCC 8739 RND family efflux transporter MFP subunit YP_001726103.1 3455941 D 481805 CDS YP_001726104.1 170021150 6066489 3457157..3460306 1 NC_010468.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_0362 acridine efflux pump; hydrophobe/amphiphile efflux-1 (HAE1) family protein 3460306 6066489 EcolC_3154 Escherichia coli ATCC 8739 hydrophobe/amphiphile efflux-1 (HAE1) family protein YP_001726104.1 3457157 D 481805 CDS YP_001726105.1 170021151 6066498 3460852..3461226 1 NC_010468.1 KEGG: sdy:SDY_0458 hypothetical protein; hypothetical protein 3461226 6066498 EcolC_3155 Escherichia coli ATCC 8739 hypothetical protein YP_001726105.1 3460852 D 481805 CDS YP_001726106.1 170021152 6066501 3461240..3461470 1 NC_010468.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 3461470 6066501 EcolC_3156 Escherichia coli ATCC 8739 hemolysin expression-modulating protein YP_001726106.1 3461240 D 481805 CDS YP_001726107.1 170021153 6066506 3461642..3462193 1 NC_010468.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: sdy:SDY_0460 putative transferase; maltose O-acetyltransferase 3462193 6066506 EcolC_3157 Escherichia coli ATCC 8739 maltose O-acetyltransferase YP_001726107.1 3461642 D 481805 CDS YP_001726108.1 170021154 6064449 3462309..3462779 1 NC_010468.1 KEGG: sdy:SDY_0461 hypothetical protein; hypothetical protein 3462779 6064449 EcolC_3158 Escherichia coli ATCC 8739 hypothetical protein YP_001726108.1 3462309 D 481805 CDS YP_001726109.1 170021155 6066513 3462943..3464493 1 NC_010468.1 PFAM: EAL domain protein; KEGG: sfv:SFV_0431 hypothetical protein; EAL domain-containing protein 3464493 6066513 EcolC_3159 Escherichia coli ATCC 8739 EAL domain-containing protein YP_001726109.1 3462943 D 481805 CDS YP_001726110.1 170021156 6066515 complement(3464535..3464888) 1 NC_010468.1 PFAM: protein of unknown function DUF1428; KEGG: sdy:SDY_0392 hypothetical protein; hypothetical protein 3464888 6066515 EcolC_3160 Escherichia coli ATCC 8739 hypothetical protein YP_001726110.1 3464535 R 481805 CDS YP_001726111.1 170021157 6066520 3465267..3465578 1 NC_010468.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: sdy:SDY_0391 hypothetical protein; methylated-DNA--protein-cysteine methyltransferase 3465578 6066520 EcolC_3161 Escherichia coli ATCC 8739 methylated-DNA--protein-cysteine methyltransferase YP_001726111.1 3465267 D 481805 CDS YP_001726112.1 170021158 6066527 complement(3465609..3466181) 1 NC_010468.1 KEGG: sfv:SFV_0427 glycoprotein/polysaccharide metabolism; glycoprotein/polysaccharide metabolism 3466181 6066527 EcolC_3162 Escherichia coli ATCC 8739 glycoprotein/polysaccharide metabolism YP_001726112.1 3465609 R 481805 CDS YP_001726113.1 170021159 6066528 3466399..3467259 1 NC_010468.1 KEGG: ssn:SSON_0440 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; acyl-CoA thioesterase II 3467259 6066528 EcolC_3163 Escherichia coli ATCC 8739 acyl-CoA thioesterase II YP_001726113.1 3466399 D 481805 CDS YP_001726114.1 170021160 6066534 complement(3467308..3468594) 1 NC_010468.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ssn:SSON_0439 probable ammonium transporter; ammonium transporter 3468594 6066534 EcolC_3164 Escherichia coli ATCC 8739 ammonium transporter YP_001726114.1 3467308 R 481805 CDS YP_001726115.1 170021161 6066537 complement(3468624..3468962) 1 NC_010468.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 3468962 6066537 EcolC_3165 Escherichia coli ATCC 8739 nitrogen regulatory protein P-II 2 YP_001726115.1 3468624 R 481805 CDS YP_001726116.1 170021162 6066540 complement(3469143..3470924) 1 NC_010468.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0344 putative ATP-binding component of a transport system; putative multidrug transporter membrane\ATP-binding proteins 3470924 6066540 EcolC_3166 Escherichia coli ATCC 8739 putative multidrug transporter membrane\ATP-binding proteins YP_001726116.1 3469143 R 481805 CDS YP_001726117.1 170021163 6066542 complement(3470917..3472689) 1 NC_010468.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_0385 ATP-binding component of a transport system; putative multidrug transporter membrane\ATP-binding proteins 3472689 6066542 EcolC_3167 Escherichia coli ATCC 8739 putative multidrug transporter membrane\ATP-binding proteins YP_001726117.1 3470917 R 481805 CDS YP_001726118.1 170021164 6065344 complement(3472719..3473177) 1 NC_010468.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sbo:SBO_0341 putative LRP-like transcriptional regulator; AsnC family transcriptional regulator 3473177 6065344 EcolC_3168 Escherichia coli ATCC 8739 AsnC family transcriptional regulator YP_001726118.1 3472719 R 481805 CDS YP_001726119.1 170021165 6066554 complement(3473330..3474097) 1 NC_010468.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: ssn:SSON_0434 hypothetical protein; cof family hydrolase 3474097 6066554 EcolC_3169 Escherichia coli ATCC 8739 cof family hydrolase YP_001726119.1 3473330 R 481805 CDS YP_001726120.1 170021166 6066556 complement(join(3474099..3474542,3474542..3474796)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 3474796 6066556 EcolC_3170 Escherichia coli ATCC 8739 insertion element protein YP_001726120.1 3474099 R 481805 CDS YP_001726121.1 170021167 6065639 complement(join(3474876..3475319,3475319..3475573)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: sfx:S4666 IS1 orfA; insertion element protein 3475573 6065639 EcolC_3171 Escherichia coli ATCC 8739 insertion element protein YP_001726121.1 3474876 R 481805 CDS YP_001726122.1 170021168 6066564 3475881..3477305 1 NC_010468.1 TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: eca:ECA0499 putative capsular polysaccharide biosynthesis protein; undecaprenyl-phosphate glucose phosphotransferase 3477305 6066564 EcolC_3172 Escherichia coli ATCC 8739 undecaprenyl-phosphate glucose phosphotransferase YP_001726122.1 3475881 D 481805 CDS YP_001726123.1 170021169 6066568 3477295..3478581 1 NC_010468.1 KEGG: eca:ECA0500 putative capsular polysaccharide biosynthesis protein; putative capsular polysaccharide biosynthesis protein 3478581 6066568 EcolC_3173 Escherichia coli ATCC 8739 putative capsular polysaccharide biosynthesis protein YP_001726123.1 3477295 D 481805 CDS YP_001726124.1 170021170 6066571 3478583..3479140 1 NC_010468.1 PFAM: polysaccharide export protein; KEGG: eca:ECA0501 putative capsular polysaccharide export protein; polysaccharide export protein 3479140 6066571 EcolC_3174 Escherichia coli ATCC 8739 polysaccharide export protein YP_001726124.1 3478583 D 481805 CDS YP_001726125.1 170021171 6066572 3479143..3481275 1 NC_010468.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA0502 putative capsulatr polysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein 3481275 6066572 EcolC_3175 Escherichia coli ATCC 8739 lipopolysaccharide biosynthesis protein YP_001726125.1 3479143 D 481805 CDS YP_001726126.1 170021172 6065747 3481272..3482483 1 NC_010468.1 KEGG: eca:ECA0503 putative capsular polysaccharide bisynthesis protein; capsular polysacharride biosynthesis protein 3482483 6065747 EcolC_3176 Escherichia coli ATCC 8739 capsular polysacharride biosynthesis protein YP_001726126.1 3481272 D 481805 CDS YP_001726127.1 170021173 6066579 3482480..3483865 1 NC_010468.1 KEGG: eca:ECA0504 putative capsular polysaccharide bisynthesis protein; capsular polysacharride biosynthesis protein 3483865 6066579 EcolC_3177 Escherichia coli ATCC 8739 capsular polysacharride biosynthesis protein YP_001726127.1 3482480 D 481805 CDS YP_001726128.1 170021174 6066084 3483855..3484844 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA0505 probable capsular polysaccharide bisynthesis glycosyl transferase; glycosyl transferase family protein 3484844 6066084 EcolC_3178 Escherichia coli ATCC 8739 glycosyl transferase family protein YP_001726128.1 3483855 D 481805 CDS YP_001726129.1 170021175 6066580 3484858..3486069 1 NC_010468.1 PFAM: glycosyl transferase group 1; KEGG: eca:ECA0506 probable capsular polysaccharide bisynthesis glycosyl transferase; group 1 glycosyl transferase 3486069 6066580 EcolC_3179 Escherichia coli ATCC 8739 group 1 glycosyl transferase YP_001726129.1 3484858 D 481805 CDS YP_001726130.1 170021176 6066582 3486071..3487183 1 NC_010468.1 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: eca:ECA0507 putative capsular polysaccharide bisynthesis glycosyl transferase; group 1 glycosyl transferase 3487183 6066582 EcolC_3180 Escherichia coli ATCC 8739 group 1 glycosyl transferase YP_001726130.1 3486071 D 481805 CDS YP_001726131.1 170021177 6066583 3487186..3487593 1 NC_010468.1 KEGG: eca:ECA0508 hypothetical protein; hypothetical protein 3487593 6066583 EcolC_3181 Escherichia coli ATCC 8739 hypothetical protein YP_001726131.1 3487186 D 481805 CDS YP_001726132.1 170021178 6066585 3487616..3489019 1 NC_010468.1 KEGG: eca:ECA0509 hypothetical protein; hypothetical protein 3489019 6066585 EcolC_3182 Escherichia coli ATCC 8739 hypothetical protein YP_001726132.1 3487616 D 481805 CDS YP_001726133.1 170021179 6066588 complement(3489067..3490086) 1 NC_010468.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase); UDP-glucose 4-epimerase 3490086 6066588 EcolC_3183 Escherichia coli ATCC 8739 UDP-glucose 4-epimerase YP_001726133.1 3489067 R 481805 CDS YP_001726134.1 170021180 6066589 complement(3490163..3491089) 1 NC_010468.1 KEGG: pdi:BDI_0028 conserved hypothetical protein, putative glycosyltransferase; hypothetical protein 3491089 6066589 EcolC_3184 Escherichia coli ATCC 8739 hypothetical protein YP_001726134.1 3490163 R 481805 CDS YP_001726135.1 170021181 6066590 join(3491436..3491690,3491690..3492133) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: sfx:S4666 IS1 orfA; insertion element protein 3492133 6066590 EcolC_3185 Escherichia coli ATCC 8739 insertion element protein YP_001726135.1 3491436 D 481805 CDS YP_001726136.1 170021182 6065561 3492321..3494021 1 NC_010468.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_0339 hypothetical protein; extracellular solute-binding protein 3494021 6065561 EcolC_3187 Escherichia coli ATCC 8739 extracellular solute-binding protein YP_001726136.1 3492321 D 481805 CDS YP_001726137.1 170021183 6066605 3494086..3494781 1 NC_010468.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 3494781 6066605 EcolC_3188 Escherichia coli ATCC 8739 queuosine biosynthesis protein QueC YP_001726137.1 3494086 D 481805 CDS YP_001726138.1 170021184 6066607 complement(3494833..3495231) 1 NC_010468.1 PFAM: thioesterase superfamily protein; KEGG: sbo:SBO_0337 hypothetical protein; thioesterase superfamily protein 3495231 6066607 EcolC_3189 Escherichia coli ATCC 8739 thioesterase superfamily protein YP_001726138.1 3494833 R 481805 CDS YP_001726139.1 170021185 6066609 complement(3495337..3495708) 1 NC_010468.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: sdy:SDY_0290 hypothetical protein; helix-hairpin-helix repeat-containing competence protein ComEA 3495708 6066609 EcolC_3190 Escherichia coli ATCC 8739 helix-hairpin-helix repeat-containing competence protein ComEA YP_001726139.1 3495337 R 481805 CDS YP_001726140.1 170021186 6066612 complement(3495859..3497730) 1 NC_010468.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: sbo:SBO_0335 putative protease maturation protein; peptidyl-prolyl cis-trans isomerase D 3497730 6066612 EcolC_3191 Escherichia coli ATCC 8739 peptidyl-prolyl cis-trans isomerase D YP_001726140.1 3495859 R 481805 CDS YP_001726141.1 170021187 6066614 complement(3497922..3498194) 1 NC_010468.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 3498194 6066614 EcolC_3192 Escherichia coli ATCC 8739 transcriptional regulator HU subunit beta YP_001726141.1 3497922 R 481805 CDS YP_001726142.1 170021188 6066618 complement(3498403..3500757) 1 NC_010468.1 KEGG: ssn:SSON_0422 DNA-binding, ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; DNA-binding ATP-dependent protease La 3500757 6066618 EcolC_3193 Escherichia coli ATCC 8739 DNA-binding ATP-dependent protease La YP_001726142.1 3498403 R 481805 CDS YP_001726143.1 170021189 6066621 complement(3500945..3502219) 1 NC_010468.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 3502219 clpX 6066621 clpX Escherichia coli ATCC 8739 ATP-dependent protease ATP-binding subunit ClpX YP_001726143.1 3500945 R 481805 CDS YP_001726144.1 170021190 6066622 complement(3502345..3502968) 1 NC_010468.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 3502968 clpP 6066622 clpP Escherichia coli ATCC 8739 ATP-dependent Clp protease proteolytic subunit YP_001726144.1 3502345 R 481805 CDS YP_001726145.1 170021191 6066627 complement(3503214..3504512) 1 NC_010468.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 3504512 tig 6066627 tig Escherichia coli ATCC 8739 trigger factor YP_001726145.1 3503214 R 481805 CDS YP_001726146.1 170021192 6065602 complement(3504659..3504847) 1 NC_010468.1 KEGG: sdy:SDY_0297 hypothetical protein; hypothetical protein 3504847 6065602 EcolC_3197 Escherichia coli ATCC 8739 hypothetical protein YP_001726146.1 3504659 R 481805 CDS YP_001726147.1 170021193 6066633 complement(3504856..3505173) 1 NC_010468.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 3505173 6066633 EcolC_3198 Escherichia coli ATCC 8739 transcriptional regulator BolA YP_001726147.1 3504856 R 481805 CDS YP_001726148.1 170021194 6066645 3505478..3506056 1 NC_010468.1 PFAM: Uncharacterized lipoprotein; KEGG: ssn:SSON_0417 putative polymerase/proteinase; hypothetical protein 3506056 6066645 EcolC_3199 Escherichia coli ATCC 8739 hypothetical protein YP_001726148.1 3505478 D 481805 CDS YP_001726149.1 170021195 6066349 3506100..3507575 1 NC_010468.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 3507575 ampG 6066349 ampG Escherichia coli ATCC 8739 muropeptide transporter YP_001726149.1 3506100 D 481805 CDS YP_001726150.1 170021196 6066653 3508037..3508984 1 NC_010468.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: sbo:SBO_0326 cytochrome o ubiquinol oxidase subunit II; cytochrome o ubiquinol oxidase subunit II 3508984 6066653 EcolC_3201 Escherichia coli ATCC 8739 cytochrome o ubiquinol oxidase subunit II YP_001726150.1 3508037 D 481805 CDS YP_001726151.1 170021197 6066657 3509006..3510997 1 NC_010468.1 KEGG: ssn:SSON_0414 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase, subunit I; PFAM: cytochrome c oxidase subunit I; cytochrome o ubiquinol oxidase subunit I 3510997 6066657 EcolC_3202 Escherichia coli ATCC 8739 cytochrome o ubiquinol oxidase subunit I YP_001726151.1 3509006 D 481805 CDS YP_001726152.1 170021198 6066663 3510987..3511601 1 NC_010468.1 TIGRFAM: cytochrome o ubiquinol oxidase, subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: ssn:SSON_0413 cytochrome o ubiquinol oxidase subunit III; cytochrome o ubiquinol oxidase subunit III 3511601 6066663 EcolC_3203 Escherichia coli ATCC 8739 cytochrome o ubiquinol oxidase subunit III YP_001726152.1 3510987 D 481805 CDS YP_001726153.1 170021199 6066664 3511601..3511930 1 NC_010468.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: sbo:SBO_0323 cytochrome o ubiquinol oxidase subunit IV; cytochrome o ubiquinol oxidase subunit IV 3511930 6066664 EcolC_3204 Escherichia coli ATCC 8739 cytochrome o ubiquinol oxidase subunit IV YP_001726153.1 3511601 D 481805 CDS YP_001726154.1 170021200 6066665 3511942..3512832 1 NC_010468.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 3512832 6066665 EcolC_3205 Escherichia coli ATCC 8739 protoheme IX farnesyltransferase YP_001726154.1 3511942 D 481805 CDS YP_001726155.1 170021201 6066451 3512981..3514345 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_0303 putative transport protein; major facilitator transporter 3514345 6066451 EcolC_3206 Escherichia coli ATCC 8739 major facilitator transporter YP_001726155.1 3512981 D 481805 CDS YP_001726156.1 170021202 6066669 complement(3514473..3514964) 1 NC_010468.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 3514964 6066669 EcolC_3207 Escherichia coli ATCC 8739 putative nucleotide-binding protein YP_001726156.1 3514473 R 481805 CDS YP_001726157.1 170021203 6066674 3515132..3516043 1 NC_010468.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 3516043 6066674 EcolC_3208 Escherichia coli ATCC 8739 2-dehydropantoate 2-reductase YP_001726157.1 3515132 D 481805 CDS YP_001726158.1 170021204 6066659 3516006..3516596 1 NC_010468.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: ssn:SSON_0401 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis; DJ-1 family protein 3516596 6066659 EcolC_3209 Escherichia coli ATCC 8739 DJ-1 family protein YP_001726158.1 3516006 D 481805 CDS YP_001726159.1 170021205 6065677 complement(3516650..3518098) 1 NC_010468.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 3518098 6065677 EcolC_3210 Escherichia coli ATCC 8739 thiamine biosynthesis protein ThiI YP_001726159.1 3516650 R 481805 CDS YP_001726160.1 170021206 6066684 3518304..3518546 1 NC_010468.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 3518546 6066684 EcolC_3211 Escherichia coli ATCC 8739 exodeoxyribonuclease VII small subunit YP_001726160.1 3518304 D 481805 CDS YP_001726161.1 170021207 6066469 3518546..3519445 1 NC_010468.1 PFAM: Polyprenyl synthetase; KEGG: sdy:SDY_0309 geranyltranstransferase; geranyltranstransferase 3519445 6066469 EcolC_3212 Escherichia coli ATCC 8739 geranyltranstransferase YP_001726161.1 3518546 D 481805 CDS YP_001726162.1 170021208 6066691 3519470..3521332 1 NC_010468.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3521332 6066691 EcolC_3213 Escherichia coli ATCC 8739 1-deoxy-D-xylulose-5-phosphate synthase YP_001726162.1 3519470 D 481805 CDS YP_001726163.1 170021209 6066697 3521512..3522486 1 NC_010468.1 PFAM: aldo/keto reductase; KEGG: sdy:SDY_0311 putative NAD(P)H-dependent xylose reductase; aldo/keto reductase 3522486 6066697 EcolC_3214 Escherichia coli ATCC 8739 aldo/keto reductase YP_001726163.1 3521512 D 481805 CDS YP_001726164.1 170021210 6066698 complement(3522540..3523058) 1 NC_010468.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 3523058 6066698 EcolC_3215 Escherichia coli ATCC 8739 phosphatidylglycerophosphatase A YP_001726164.1 3522540 R 481805 CDS YP_001726165.1 170021211 6066699 complement(3523036..3524013) 1 NC_010468.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 3524013 6066699 EcolC_3216 Escherichia coli ATCC 8739 thiamine monophosphate kinase YP_001726165.1 3523036 R 481805 CDS YP_001726166.1 170021212 6066701 complement(3524091..3524510) 1 NC_010468.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 3524510 nusB 6066701 nusB Escherichia coli ATCC 8739 transcription antitermination protein NusB YP_001726166.1 3524091 R 481805 CDS YP_001726167.1 170021213 6066713 complement(3524530..3525000) 1 NC_010468.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 3525000 ribH 6066713 ribH Escherichia coli ATCC 8739 6,7-dimethyl-8-ribityllumazine synthase YP_001726167.1 3524530 R 481805 CDS YP_001726168.1 170021214 6066717 complement(3525089..3526192) 1 NC_010468.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 3526192 ribD 6066717 ribD Escherichia coli ATCC 8739 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_001726168.1 3525089 R 481805 CDS YP_001726169.1 170021215 6066718 complement(3526196..3526645) 1 NC_010468.1 PFAM: ATP-cone domain protein; KEGG: sdy:SDY_0321 hypothetical protein; transcriptional regulator NrdR 3526645 nrdR 6066718 nrdR Escherichia coli ATCC 8739 transcriptional regulator NrdR YP_001726169.1 3526196 R 481805 CDS YP_001726170.1 170021216 6066720 3526796..3527335 1 NC_010468.1 KEGG: ssn:SSON_0389 hypothetical protein; hypothetical protein 3527335 6066720 EcolC_3221 Escherichia coli ATCC 8739 hypothetical protein YP_001726170.1 3526796 D 481805 CDS YP_001726171.1 170021217 6066723 3527634..3528518 1 NC_010468.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: sdy:SDY_0323 nucleoside channel; nucleoside-specific channel-forming protein Tsx 3528518 6066723 EcolC_3222 Escherichia coli ATCC 8739 nucleoside-specific channel-forming protein Tsx YP_001726171.1 3527634 D 481805 CDS YP_001726172.1 170021218 6066725 complement(3528695..3529042) 1 NC_010468.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: sdy:SDY_0324 hypothetical protein; hypothetical protein 3529042 6066725 EcolC_3223 Escherichia coli ATCC 8739 hypothetical protein YP_001726172.1 3528695 R 481805 CDS YP_001726173.1 170021219 6066726 complement(3529170..3530141) 1 NC_010468.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 3530141 secF 6066726 secF Escherichia coli ATCC 8739 preprotein translocase subunit SecF YP_001726173.1 3529170 R 481805 CDS YP_001726174.1 170021220 6066729 complement(3530152..3531966) 1 NC_010468.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 3531966 secD 6066729 secD Escherichia coli ATCC 8739 preprotein translocase subunit SecD YP_001726174.1 3530152 R 481805 CDS YP_001726175.1 170021221 6064945 complement(3532027..3532359) 1 NC_010468.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 3532359 yajC 6064945 yajC Escherichia coli ATCC 8739 preprotein translocase subunit YajC YP_001726175.1 3532027 R 481805 CDS YP_001726176.1 170021222 6066743 complement(3532382..3533509) 1 NC_010468.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 3533509 tgt 6066743 tgt Escherichia coli ATCC 8739 queuine tRNA-ribosyltransferase YP_001726176.1 3532382 R 481805 CDS YP_001726177.1 170021223 6066744 complement(3533565..3534635) 1 NC_010468.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 3534635 queA 6066744 queA Escherichia coli ATCC 8739 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001726177.1 3533565 R 481805 CDS YP_001726178.1 170021224 6066748 3534728..3535309 1 NC_010468.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 3535309 6066748 EcolC_3229 Escherichia coli ATCC 8739 acyl carrier protein phosphodiesterase YP_001726178.1 3534728 D 481805 CDS YP_001726179.1 170021225 6066764 complement(3535314..3537131) 1 NC_010468.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ssn:SSON_0380 maltodextrin glucosidase; maltodextrin glucosidase 3537131 6066764 EcolC_3230 Escherichia coli ATCC 8739 maltodextrin glucosidase YP_001726179.1 3535314 R 481805 CDS YP_001726180.1 170021226 6066766 complement(3537287..3538660) 1 NC_010468.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 3538660 proY 6066766 proY Escherichia coli ATCC 8739 putative proline-specific permease YP_001726180.1 3537287 R 481805 CDS YP_001726181.1 170021227 6066769 complement(3538736..3540055) 1 NC_010468.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: sdy:SDY_0336 branched chain amino acid transport system II carrier protein; branched-chain amino acid transport system II carrier protein 3540055 6066769 EcolC_3232 Escherichia coli ATCC 8739 branched-chain amino acid transport system II carrier protein YP_001726181.1 3538736 R 481805 CDS YP_001726182.1 170021228 6066771 complement(3540462..3541757) 1 NC_010468.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 3541757 phoR 6066771 phoR Escherichia coli ATCC 8739 phosphate regulon sensor protein YP_001726182.1 3540462 R 481805 CDS YP_001726183.1 170021229 6066779 complement(3541815..3542504) 1 NC_010468.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 3542504 6066779 EcolC_3234 Escherichia coli ATCC 8739 transcriptional regulator PhoB YP_001726183.1 3541815 R 481805 CDS YP_001726184.1 170021230 6066781 3542694..3543896 1 NC_010468.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 3543896 6066781 EcolC_3235 Escherichia coli ATCC 8739 exonuclease subunit SbcD YP_001726184.1 3542694 D 481805 CDS YP_001726185.1 170021231 6066787 3543893..3547036 1 NC_010468.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 3547036 6066787 EcolC_3236 Escherichia coli ATCC 8739 exonuclease subunit SbcC YP_001726185.1 3543893 D 481805 CDS YP_001726186.1 170021232 6066789 3547162..3548346 1 NC_010468.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 3548346 6066789 EcolC_3237 Escherichia coli ATCC 8739 MFS transport protein AraJ YP_001726186.1 3547162 D 481805 CDS YP_001726187.1 170021233 6066795 complement(3548591..3549586) 1 NC_010468.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 3549586 6066795 EcolC_3238 Escherichia coli ATCC 8739 fructokinase YP_001726187.1 3548591 R 481805 CDS YP_001726188.1 170021234 6064785 3549624..3550535 1 NC_010468.1 Required for efficient pilin antigenic variation; recombination associated protein 3550535 rdgC 6064785 rdgC Escherichia coli ATCC 8739 recombination associated protein YP_001726188.1 3549624 D 481805 CDS YP_001726189.1 170021235 6066797 complement(3550693..3550974) 1 NC_010468.1 KEGG: sfv:SFV_0357 hypothetical protein; hypothetical protein 3550974 6066797 EcolC_3240 Escherichia coli ATCC 8739 hypothetical protein YP_001726189.1 3550693 R 481805 CDS YP_001726190.1 170021236 6066798 complement(3551182..3551466) 1 NC_010468.1 PFAM: protein of unknown function DUF1255; KEGG: sbo:SBO_0286 hypothetical protein; hypothetical protein 3551466 6066798 EcolC_3241 Escherichia coli ATCC 8739 hypothetical protein YP_001726190.1 3551182 R 481805 CDS YP_001726191.1 170021237 6066800 complement(3551538..3552215) 1 NC_010468.1 PFAM: AroM family protein; KEGG: sbo:SBO_0285 AroM; hypothetical protein 3552215 6066800 EcolC_3242 Escherichia coli ATCC 8739 hypothetical protein YP_001726191.1 3551538 R 481805 CDS YP_001726192.1 170021238 6066804 complement(3552473..3552664) 1 NC_010468.1 KEGG: sbo:SBO_0284 hypothetical protein; hypothetical protein 3552664 6066804 EcolC_3243 Escherichia coli ATCC 8739 hypothetical protein YP_001726192.1 3552473 R 481805 CDS YP_001726193.1 170021239 6066807 complement(3552714..3553238) 1 NC_010468.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 3553238 aroL 6066807 aroL Escherichia coli ATCC 8739 shikimate kinase YP_001726193.1 3552714 R 481805 CDS YP_001726194.1 170021240 6066810 complement(3553415..3553879) 1 NC_010468.1 PFAM: protein of unknown function DUF188; KEGG: sdy:SDY_0357 hypothetical protein; hypothetical protein 3553879 6066810 EcolC_3245 Escherichia coli ATCC 8739 hypothetical protein YP_001726194.1 3553415 R 481805 CDS YP_001726195.1 170021241 6066812 3553999..3554808 1 NC_010468.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 3554808 6066812 EcolC_3246 Escherichia coli ATCC 8739 pyrroline-5-carboxylate reductase YP_001726195.1 3553999 D 481805 CDS YP_001726196.1 170021242 6066813 complement(3554825..3555940) 1 NC_010468.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 3555940 adrA 6066813 adrA Escherichia coli ATCC 8739 diguanylate cyclase AdrA YP_001726196.1 3554825 R 481805 CDS YP_001726197.1 170021243 6066819 complement(3556042..3556362) 1 NC_010468.1 PFAM: PsiF repeat protein; KEGG: sbo:SBO_0279 PsiF; hypothetical protein 3556362 6066819 EcolC_3248 Escherichia coli ATCC 8739 hypothetical protein YP_001726197.1 3556042 R 481805 CDS YP_001726198.1 170021244 6066034 complement(3556481..3557896) 1 NC_010468.1 PFAM: Alkaline phosphatase; KEGG: sbo:SBO_0278 alkaline phosphatase; alkaline phosphatase 3557896 6066034 EcolC_3249 Escherichia coli ATCC 8739 alkaline phosphatase YP_001726198.1 3556481 R 481805 CDS YP_001726199.1 170021245 6066821 complement(3557997..3558257) 1 NC_010468.1 KEGG: ssn:SSON_0357 hypothetical protein; hypothetical protein 3558257 6066821 EcolC_3250 Escherichia coli ATCC 8739 hypothetical protein YP_001726199.1 3557997 R 481805 CDS YP_001726200.1 170021246 6066822 3558720..3559814 1 NC_010468.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 3559814 ddl 6066822 ddl Escherichia coli ATCC 8739 D-alanyl-alanine synthetase A YP_001726200.1 3558720 D 481805 CDS YP_001726201.1 170021247 6066826 complement(3559838..3560050) 1 NC_010468.1 KEGG: sdy:SDY_0366 hypothetical protein; hypothetical protein 3560050 6066826 EcolC_3252 Escherichia coli ATCC 8739 hypothetical protein YP_001726201.1 3559838 R 481805 CDS YP_001726202.1 170021248 6065894 3560310..3560618 1 NC_010468.1 KEGG: sbo:SBO_0274 hypothetical protein; hypothetical protein 3560618 6065894 EcolC_3253 Escherichia coli ATCC 8739 hypothetical protein YP_001726202.1 3560310 D 481805 CDS YP_001726203.1 170021249 6066828 complement(3560677..3561771) 1 NC_010468.1 PFAM: protein of unknown function DUF1615; KEGG: sbo:SBO_0273 hypothetical protein; hypothetical protein 3561771 6066828 EcolC_3254 Escherichia coli ATCC 8739 hypothetical protein YP_001726203.1 3560677 R 481805 CDS YP_001726204.1 170021250 6066041 complement(3561784..3563004) 1 NC_010468.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 3563004 6066041 EcolC_3255 Escherichia coli ATCC 8739 transporter YP_001726204.1 3561784 R 481805 CDS YP_001726205.1 170021251 6066831 3563356..3564513 1 NC_010468.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 3564513 6066831 EcolC_3256 Escherichia coli ATCC 8739 beta-lactam binding protein AmpH YP_001726205.1 3563356 D 481805 CDS YP_001726206.1 170021252 6066832 complement(3564514..3565137) 1 NC_010468.1 KEGG: ssn:SSON_0350 hypothetical protein; putative DNA-binding transcriptional regulator 3565137 6066832 EcolC_3257 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001726206.1 3564514 R 481805 CDS YP_001726207.1 170021253 6066834 complement(3565225..3568227) 1 NC_010468.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: cko:CKO_02805 hypothetical protein; outer membrane autotransporter 3568227 6066834 EcolC_3258 Escherichia coli ATCC 8739 outer membrane autotransporter YP_001726207.1 3565225 R 481805 CDS YP_001726208.1 170021254 6066839 3568750..3569724 1 NC_010468.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 3569724 6066839 EcolC_3259 Escherichia coli ATCC 8739 delta-aminolevulinic acid dehydratase YP_001726208.1 3568750 D 481805 CDS YP_001726209.1 170021255 6066840 complement(3569831..3570682) 1 NC_010468.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 3570682 tauD 6066840 tauD Escherichia coli ATCC 8739 taurine dioxygenase YP_001726209.1 3569831 R 481805 CDS YP_001726210.1 170021256 6066841 complement(3570679..3571506) 1 NC_010468.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_0331 taurine transport system permease protein; taurine transporter subunit 3571506 6066841 EcolC_3261 Escherichia coli ATCC 8739 taurine transporter subunit YP_001726210.1 3570679 R 481805 CDS YP_001726211.1 170021257 6066851 complement(3571503..3572270) 1 NC_010468.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 3572270 tauB 6066851 tauB Escherichia coli ATCC 8739 taurine transporter ATP-binding subunit YP_001726211.1 3571503 R 481805 CDS YP_001726212.1 170021258 6066854 complement(3572283..3573245) 1 NC_010468.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 3573245 tauA 6066854 tauA Escherichia coli ATCC 8739 taurine transporter substrate binding subunit YP_001726212.1 3572283 R 481805 CDS YP_001726213.1 170021259 6065013 3573861..3574532 1 NC_010468.1 PFAM: LmbE family protein; KEGG: ssn:SSON_0340 hypothetical protein; LmbE family protein 3574532 6065013 EcolC_3264 Escherichia coli ATCC 8739 LmbE family protein YP_001726213.1 3573861 D 481805 CDS YP_001726214.1 170021260 6066857 3574542..3575738 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: aau:AAur_0762 glycosyl transferase, group 2 family domain protein; glycosyl transferase family protein 3575738 6066857 EcolC_3265 Escherichia coli ATCC 8739 glycosyl transferase family protein YP_001726214.1 3574542 D 481805 CDS YP_001726215.1 170021261 6066274 3575857..3576297 1 NC_010468.1 KEGG: ssn:SSON_0338 putative transferase; putative transferase 3576297 6066274 EcolC_3266 Escherichia coli ATCC 8739 putative transferase YP_001726215.1 3575857 D 481805 CDS YP_001726216.1 170021262 6066863 3576299..3577072 1 NC_010468.1 KEGG: ssn:SSON_0337 hypothetical protein; hypothetical protein 3577072 6066863 EcolC_3267 Escherichia coli ATCC 8739 hypothetical protein YP_001726216.1 3576299 D 481805 CDS YP_001726217.1 170021263 6064941 3577258..3577533 1 NC_010468.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 3577533 6064941 EcolC_3268 Escherichia coli ATCC 8739 regulator protein FrmR YP_001726217.1 3577258 D 481805 CDS YP_001726218.1 170021264 6066867 3577568..3578677 1 NC_010468.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_0335 alcohol dehydrogenase class III; S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3578677 6066867 EcolC_3269 Escherichia coli ATCC 8739 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase YP_001726218.1 3577568 D 481805 CDS YP_001726219.1 170021265 6065536 3578770..3579603 1 NC_010468.1 KEGG: ssn:SSON_0334 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; S-formylglutathione hydrolase 3579603 6065536 EcolC_3270 Escherichia coli ATCC 8739 S-formylglutathione hydrolase YP_001726219.1 3578770 D 481805 CDS YP_001726220.1 170021266 6066871 complement(3579829..3580368) 1 NC_010468.1 KEGG: ssn:SSON_0333 nucleoprotein/polynucleotide-associated enzyme; nucleoprotein/polynucleotide-associated protein 3580368 6066871 EcolC_3271 Escherichia coli ATCC 8739 nucleoprotein/polynucleotide-associated protein YP_001726220.1 3579829 R 481805 CDS YP_001726221.1 170021267 6066896 complement(3580470..3581681) 1 NC_010468.1 TIGRFAM: benzoate transport; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_0332 putative transport protein; putative 3-hydroxyphenylpropionic transporter MhpT 3581681 6066896 EcolC_3272 Escherichia coli ATCC 8739 putative 3-hydroxyphenylpropionic transporter MhpT YP_001726221.1 3580470 R 481805 CDS YP_001726222.1 170021268 6065774 complement(3582158..3583171) 1 NC_010468.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 3583171 6065774 EcolC_3273 Escherichia coli ATCC 8739 4-hydroxy-2-ketovalerate aldolase YP_001726222.1 3582158 R 481805 CDS YP_001726223.1 170021269 6066910 complement(3583168..3584118) 1 NC_010468.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 3584118 6066910 EcolC_3274 Escherichia coli ATCC 8739 acetaldehyde dehydrogenase YP_001726223.1 3583168 R 481805 CDS YP_001726224.1 170021270 6066915 complement(3584115..3584924) 1 NC_010468.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 3584924 mhpD 6066915 mhpD Escherichia coli ATCC 8739 2-keto-4-pentenoate hydratase YP_001726224.1 3584115 R 481805 CDS YP_001726225.1 170021271 6065694 complement(3584934..3585800) 1 NC_010468.1 PFAM: alpha/beta hydrolase fold; KEGG: kpn:KPN_02120 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; alpha/beta hydrolase fold protein 3585800 6065694 EcolC_3276 Escherichia coli ATCC 8739 alpha/beta hydrolase fold protein YP_001726225.1 3584934 R 481805 CDS YP_001726226.1 170021272 6066918 complement(3585818..3586762) 1 NC_010468.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 3586762 mhpB 6066918 mhpB Escherichia coli ATCC 8739 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_001726226.1 3585818 R 481805 CDS YP_001726227.1 170021273 6066939 complement(3586764..3588428) 1 NC_010468.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 3588428 mhpA 6066939 mhpA Escherichia coli ATCC 8739 3-(3-hydroxyphenyl)propionate hydroxylase YP_001726227.1 3586764 R 481805 CDS YP_001726228.1 170021274 6066679 3588607..3589452 1 NC_010468.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 3589452 6066679 EcolC_3279 Escherichia coli ATCC 8739 DNA-binding transcriptional activator MhpR YP_001726228.1 3588607 D 481805 CDS YP_001726229.1 170021275 6066942 3589520..3590611 1 NC_010468.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 3590611 lacI 6066942 lacI Escherichia coli ATCC 8739 lac repressor YP_001726229.1 3589520 D 481805 CDS YP_001726230.1 170021276 6066946 3590734..3593808 1 NC_010468.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 3593808 lacZ 6066946 lacZ Escherichia coli ATCC 8739 beta-D-galactosidase YP_001726230.1 3590734 D 481805 CDS YP_001726231.1 170021277 6066950 3593860..3595113 1 NC_010468.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 3595113 lacY 6066950 lacY Escherichia coli ATCC 8739 galactoside permease YP_001726231.1 3593860 D 481805 CDS YP_001726232.1 170021278 6066969 3595185..3595790 1 NC_010468.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 3595790 lacA 6066969 lacA Escherichia coli ATCC 8739 galactoside O-acetyltransferase YP_001726232.1 3595185 D 481805 CDS YP_001726233.1 170021279 6066972 complement(3595893..3597074) 1 NC_010468.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; putative cyanate transporter 3597074 cynX 6066972 cynX Escherichia coli ATCC 8739 putative cyanate transporter YP_001726233.1 3595893 R 481805 CDS YP_001726234.1 170021280 6066978 complement(3597080..3597550) 1 NC_010468.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 3597550 6066978 EcolC_3285 Escherichia coli ATCC 8739 cyanate hydratase YP_001726234.1 3597080 R 481805 CDS YP_001726235.1 170021281 6066980 complement(3597581..3598240) 1 NC_010468.1 PFAM: carbonic anhydrase; KEGG: pen:PSEEN3600 carbonic anhydrase; carbonate dehydratase 3598240 6066980 EcolC_3286 Escherichia coli ATCC 8739 carbonate dehydratase YP_001726235.1 3597581 R 481805 CDS YP_001726236.1 170021282 6066983 3598350..3599249 1 NC_010468.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR 3599249 6066983 EcolC_3287 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator CynR YP_001726236.1 3598350 D 481805 CDS YP_001726237.1 170021283 6066989 complement(3599586..3600869) 1 NC_010468.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 3600869 6066989 EcolC_3288 Escherichia coli ATCC 8739 cytosine deaminase YP_001726237.1 3599586 R 481805 CDS YP_001726238.1 170021284 6066992 complement(3600859..3602118) 1 NC_010468.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sec:SC3271 putative purine-cytosine permease; cytosine permease 3602118 codB 6066992 codB Escherichia coli ATCC 8739 cytosine permease YP_001726238.1 3600859 R 481805 CDS YP_001726239.1 170021285 6066997 complement(3602542..3604428) 1 NC_010468.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 3604428 prpE 6066997 prpE Escherichia coli ATCC 8739 propionyl-CoA synthetase YP_001726239.1 3602542 R 481805 CDS YP_001726240.1 170021286 6065087 complement(3604468..3605919) 1 NC_010468.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 3605919 prpD 6065087 prpD Escherichia coli ATCC 8739 2-methylcitrate dehydratase YP_001726240.1 3604468 R 481805 CDS YP_001726241.1 170021287 6067028 complement(3605953..3607122) 1 NC_010468.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 3607122 6067028 EcolC_3292 Escherichia coli ATCC 8739 methylcitrate synthase YP_001726241.1 3605953 R 481805 CDS YP_001726242.1 170021288 6067033 complement(3607469..3608359) 1 NC_010468.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 3608359 prpB 6067033 prpB Escherichia coli ATCC 8739 2-methylisocitrate lyase YP_001726242.1 3607469 R 481805 CDS YP_001726243.1 170021289 6067058 3608598..3610184 1 NC_010468.1 KEGG: cko:CKO_02831 hypothetical protein; TIGRFAM: propionate catabolism operon regulatory protein PrpR; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; Propionate catabolism activator domain protein; SMART: AAA ATPase; Fis family proprionate catabolism activator 3610184 6067058 EcolC_3294 Escherichia coli ATCC 8739 Fis family proprionate catabolism activator YP_001726243.1 3608598 D 481805 CDS YP_001726244.1 170021290 6064779 complement(3610282..3610557) 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: cko:CKO_02832 hypothetical protein; hypothetical protein 3610557 6064779 EcolC_3295 Escherichia coli ATCC 8739 hypothetical protein YP_001726244.1 3610282 R 481805 CDS YP_001726245.1 170021291 6067068 3610704..3611375 1 NC_010468.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ssn:SSON_0302 putative cytochrome subunit of dehydrogenase; homoserine/threonine efflux pump 3611375 6067068 EcolC_3296 Escherichia coli ATCC 8739 homoserine/threonine efflux pump YP_001726245.1 3610704 D 481805 CDS YP_001726246.1 170021292 6067075 complement(3612050..3612865) 1 NC_010468.1 KEGG: ssn:SSON_0306 hypothetical protein; hypothetical protein 3612865 6067075 EcolC_3297 Escherichia coli ATCC 8739 hypothetical protein YP_001726246.1 3612050 R 481805 CDS YP_001726247.1 170021293 6067078 complement(3613108..3614157) 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_0308 putative oxidoreductase; alcohol dehydrogenase 3614157 6067078 EcolC_3298 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001726247.1 3613108 R 481805 CDS YP_001726248.1 170021294 6066353 complement(3614534..3615916) 1 NC_010468.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; putative deaminase 3615916 6066353 EcolC_3299 Escherichia coli ATCC 8739 putative deaminase YP_001726248.1 3614534 R 481805 CDS YP_001726249.1 170021295 6067085 complement(3615926..3616876) 1 NC_010468.1 PFAM: aspartate/glutamate/uridylate kinase; KEGG: ssn:SSON_0310 putative kinase; putative carbamate kinase 3616876 6067085 EcolC_3300 Escherichia coli ATCC 8739 putative carbamate kinase YP_001726249.1 3615926 R 481805 CDS YP_001726250.1 170021296 6067087 complement(3616952..3617248) 1 NC_010468.1 hypothetical protein 3617248 6067087 EcolC_3301 Escherichia coli ATCC 8739 hypothetical protein YP_001726250.1 3616952 R 481805 CDS YP_001726251.1 170021297 6067088 complement(3617298..3618716) 1 NC_010468.1 PFAM: protein of unknown function DUF1116; KEGG: ssn:SSON_0311 hypothetical protein; hypothetical protein 3618716 6067088 EcolC_3302 Escherichia coli ATCC 8739 hypothetical protein YP_001726251.1 3617298 R 481805 CDS YP_001726252.1 170021298 6067099 complement(3618716..3620263) 1 NC_010468.1 PFAM: FdrA family protein; KEGG: ssn:SSON_0312 putative oxidoreductase subunit; FdrA family protein 3620263 6067099 EcolC_3303 Escherichia coli ATCC 8739 FdrA family protein YP_001726252.1 3618716 R 481805 CDS YP_001726253.1 170021299 6067102 complement(3620253..3621116) 1 NC_010468.1 KEGG: ssn:SSON_0313 hypothetical protein; hypothetical protein 3621116 6067102 EcolC_3304 Escherichia coli ATCC 8739 hypothetical protein YP_001726253.1 3620253 R 481805 CDS YP_001726254.1 170021300 6067129 complement(3621156..3621761) 1 NC_010468.1 PFAM: Ankyrin; KEGG: ent:Ent638_3145 ankyrin; ankyrin 3621761 6067129 EcolC_3305 Escherichia coli ATCC 8739 ankyrin YP_001726254.1 3621156 R 481805 CDS YP_001726255.1 170021301 6067131 3622019..3622516 1 NC_010468.1 PFAM: protein of unknown function DUF1097; KEGG: ctc:CTC01779 glutathione-regulated potassium-efflux system protein; hypothetical protein 3622516 6067131 EcolC_3306 Escherichia coli ATCC 8739 hypothetical protein YP_001726255.1 3622019 D 481805 CDS YP_001726256.1 170021302 6067142 3622608..3623540 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_3146 transcriptional regulator, LysR family; LysR family transcriptional regulator 3623540 6067142 EcolC_3307 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001726256.1 3622608 D 481805 CDS YP_001726257.1 170021303 6067063 complement(3623582..3624670) 1 NC_010468.1 PFAM: regulatory protein LuxR; EAL domain protein; KEGG: aha:AHA_3485 Rtn protein; diguanylate phosphodiesterase 3624670 6067063 EcolC_3308 Escherichia coli ATCC 8739 diguanylate phosphodiesterase YP_001726257.1 3623582 R 481805 CDS YP_001726258.1 170021304 6067154 complement(3625545..3627578) 1 NC_010468.1 proton-motive-force-driven choline transporter; choline transport protein BetT 3627578 6067154 EcolC_3309 Escherichia coli ATCC 8739 choline transport protein BetT YP_001726258.1 3625545 R 481805 CDS YP_001726259.1 170021305 6066404 3627707..3628294 1 NC_010468.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 3628294 6066404 EcolC_3310 Escherichia coli ATCC 8739 transcriptional regulator BetI YP_001726259.1 3627707 D 481805 CDS YP_001726260.1 170021306 6067157 3628308..3629780 1 NC_010468.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 3629780 6067157 EcolC_3311 Escherichia coli ATCC 8739 betaine aldehyde dehydrogenase YP_001726260.1 3628308 D 481805 CDS YP_001726261.1 170021307 6065713 3629794..3631464 1 NC_010468.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 3631464 6065713 EcolC_3312 Escherichia coli ATCC 8739 choline dehydrogenase YP_001726261.1 3629794 D 481805 CDS YP_001726262.1 170021308 6067159 3631677..3632345 1 NC_010468.1 KEGG: sfv:SFV_0321 hypothetical protein; hypothetical protein 3632345 6067159 EcolC_3313 Escherichia coli ATCC 8739 hypothetical protein YP_001726262.1 3631677 D 481805 CDS YP_001726263.1 170021309 6066599 complement(3632588..3633283) 1 NC_010468.1 PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0319 putative transporter; hypothetical protein 3633283 6066599 EcolC_3314 Escherichia coli ATCC 8739 hypothetical protein YP_001726263.1 3632588 R 481805 CDS YP_001726264.1 170021310 6067164 complement(3633276..3634703) 1 NC_010468.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0318 hypothetical protein; iron-sulfur cluster binding protein 3634703 6067164 EcolC_3315 Escherichia coli ATCC 8739 iron-sulfur cluster binding protein YP_001726264.1 3633276 R 481805 CDS YP_001726265.1 170021311 6067177 complement(3634714..3635433) 1 NC_010468.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: ssn:SSON_0318 putative dehydrogenase subunit; hypothetical protein 3635433 6067177 EcolC_3316 Escherichia coli ATCC 8739 hypothetical protein YP_001726265.1 3634714 R 481805 CDS YP_001726266.1 170021312 6067197 complement(3635960..3636814) 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_0319 putative AraC-type regulatory protein; AraC family transcriptional regulator 3636814 6067197 EcolC_3317 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726266.1 3635960 R 481805 CDS YP_001726267.1 170021313 6067200 3637040..3638365 1 NC_010468.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 3638365 6067200 EcolC_3318 Escherichia coli ATCC 8739 pyridine nucleotide-disulfide oxidoreductase YP_001726267.1 3637040 D 481805 CDS YP_001726268.1 170021314 6067210 3638722..3639315 1 NC_010468.1 PFAM: protein of unknown function DUF417; KEGG: ssn:SSON_0322 hypothetical protein; hypothetical protein 3639315 6067210 EcolC_3319 Escherichia coli ATCC 8739 hypothetical protein YP_001726268.1 3638722 D 481805 CDS YP_001726269.1 170021315 6067215 3639905..3640756 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: stm:STM1671 putative regulatory protein; AraC family transcriptional regulator 3640756 6067215 EcolC_3321 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726269.1 3639905 D 481805 CDS YP_001726270.1 170021316 6067220 complement(3640896..3645152) 1 NC_010468.1 PFAM: Ig domain protein group 1 domain protein; KEGG: ypi:YpsIP31758_0608 putative invasin; Ig domain-containing protein 3645152 6067220 EcolC_3322 Escherichia coli ATCC 8739 Ig domain-containing protein YP_001726270.1 3640896 R 481805 CDS YP_001726271.1 170021317 6067231 3646730..3646996 1 NC_010468.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 3646996 rpmE2 6067231 rpmE2 Escherichia coli ATCC 8739 50S ribosomal protein L31 YP_001726271.1 3646730 D 481805 CDS YP_001726272.1 170021318 6067237 3646996..3647136 1 NC_010468.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 3647136 rpmJ 6067237 rpmJ Escherichia coli ATCC 8739 50S ribosomal protein L36 YP_001726272.1 3646996 D 481805 CDS YP_001726273.1 170021319 6066687 3648222..3648764 1 NC_010468.1 PFAM: regulatory protein LuxR; KEGG: sbo:SBO_0225 putative regulator; LuxR family transcriptional regulator 3648764 6066687 EcolC_3325 Escherichia coli ATCC 8739 LuxR family transcriptional regulator YP_001726273.1 3648222 D 481805 CDS YP_001726274.1 170021320 6067251 3648839..3649426 1 NC_010468.1 KEGG: sbo:SBO_0226 hypothetical protein; hypothetical protein 3649426 6067251 EcolC_3326 Escherichia coli ATCC 8739 hypothetical protein YP_001726274.1 3648839 D 481805 CDS YP_001726275.1 170021321 6067272 3649484..3650152 1 NC_010468.1 KEGG: sbo:SBO_0227 hypothetical protein; hypothetical protein 3650152 6067272 EcolC_3327 Escherichia coli ATCC 8739 hypothetical protein YP_001726275.1 3649484 D 481805 CDS YP_001726276.1 170021322 6067293 join(3650178..3651461,3651463..3652704) 1 NC_010468.1 KEGG: kpn:KPN_00293 putative enzyme; hypothetical protein 3652704 6067293 EcolC_3328 Escherichia coli ATCC 8739 hypothetical protein YP_001726276.1 3650178 D 481805 CDS YP_001726277.1 170021323 6067294 3652694..3654337 1 NC_010468.1 KEGG: kpn:KPN_00294 putative receptor; putative receptor 3654337 6067294 EcolC_3329 Escherichia coli ATCC 8739 putative receptor YP_001726277.1 3652694 D 481805 CDS YP_001726278.1 170021324 6067295 3654360..3655016 1 NC_010468.1 KEGG: kpn:KPN_00295 hypothetical protein; hypothetical protein 3655016 6067295 EcolC_3330 Escherichia coli ATCC 8739 hypothetical protein YP_001726278.1 3654360 D 481805 CDS YP_001726279.1 170021325 6067301 3655329..3655658 1 NC_010468.1 PFAM: protein of unknown function UPF0153; KEGG: esa:ESA_01555 hypothetical protein; hypothetical protein 3655658 6067301 EcolC_3331 Escherichia coli ATCC 8739 hypothetical protein YP_001726279.1 3655329 D 481805 CDS YP_001726280.1 170021326 6066732 complement(3655906..3656520) 1 NC_010468.1 PFAM: protein of unknown function DUF1440; KEGG: ent:Ent638_2282 protein of unknown function DUF1440; hypothetical protein 3656520 6066732 EcolC_3332 Escherichia coli ATCC 8739 hypothetical protein YP_001726280.1 3655906 R 481805 CDS YP_001726281.1 170021327 6067314 3656938..3657627 1 NC_010468.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: esa:ESA_04143 hypothetical protein; putative xanthine dehydrogenase iron-sulfur-binding subunit 3657627 6067314 EcolC_3333 Escherichia coli ATCC 8739 putative xanthine dehydrogenase iron-sulfur-binding subunit YP_001726281.1 3656938 D 481805 CDS YP_001726282.1 170021328 6067317 3657624..3658580 1 NC_010468.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: esa:ESA_04145 hypothetical protein; FAD-binding molybdopterin dehydrogenase 3658580 6067317 EcolC_3334 Escherichia coli ATCC 8739 FAD-binding molybdopterin dehydrogenase YP_001726282.1 3657624 D 481805 CDS YP_001726283.1 170021329 6065177 3658577..3660775 1 NC_010468.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: esa:ESA_04146 hypothetical protein; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 3660775 6065177 EcolC_3335 Escherichia coli ATCC 8739 molybdopterin binding aldehyde oxidase and xanthine dehydrogenase YP_001726283.1 3658577 D 481805 CDS YP_001726284.1 170021330 6067324 3660785..3661741 1 NC_010468.1 PFAM: protein of unknown function DUF182; KEGG: esa:ESA_04147 hypothetical protein; hypothetical protein 3661741 6067324 EcolC_3336 Escherichia coli ATCC 8739 hypothetical protein YP_001726284.1 3660785 D 481805 CDS YP_001726285.1 170021331 6067214 3661720..3662130 1 NC_010468.1 KEGG: smd:Smed_5891 transcriptional regulator, LysR family; hypothetical protein 3662130 6067214 EcolC_3337 Escherichia coli ATCC 8739 hypothetical protein YP_001726285.1 3661720 D 481805 CDS YP_001726286.1 170021332 6067335 complement(3662447..3663700) 1 NC_010468.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 3663700 proA 6067335 proA Escherichia coli ATCC 8739 gamma-glutamyl phosphate reductase YP_001726286.1 3662447 R 481805 CDS YP_001726287.1 170021333 6067338 complement(3663712..3664815) 1 NC_010468.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 3664815 6067338 EcolC_3339 Escherichia coli ATCC 8739 gamma-glutamyl kinase YP_001726287.1 3663712 R 481805 CDS YP_001726288.1 170021334 6067357 3665103..3666158 1 NC_010468.1 PFAM: porin Gram-negative type; KEGG: sbo:SBO_0247 outer membrane pore protein E; outer membrane phosphoporin protein E 3666158 6067357 EcolC_3340 Escherichia coli ATCC 8739 outer membrane phosphoporin protein E YP_001726288.1 3665103 D 481805 CDS YP_001726289.1 170021335 6067358 complement(3666197..3666598) 1 NC_010468.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 3666598 6067358 EcolC_3341 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator Crl YP_001726289.1 3666197 R 481805 CDS YP_001726290.1 170021336 6067362 complement(3666656..3667900) 1 NC_010468.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 3667900 frsA 6067362 frsA Escherichia coli ATCC 8739 fermentation/respiration switch protein YP_001726290.1 3666656 R 481805 CDS YP_001726291.1 170021337 6067366 complement(3667992..3668450) 1 NC_010468.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 3668450 6067366 EcolC_3343 Escherichia coli ATCC 8739 xanthine-guanine phosphoribosyltransferase YP_001726291.1 3667992 R 481805 CDS YP_001726292.1 170021338 6067368 3668711..3670168 1 NC_010468.1 KEGG: sdy:SDY_0480 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; aminoacyl-histidine dipeptidase 3670168 6067368 EcolC_3344 Escherichia coli ATCC 8739 aminoacyl-histidine dipeptidase YP_001726292.1 3668711 D 481805 CDS YP_001726293.1 170021339 6067391 complement(join(3670864..3671307,3671307..3671561)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 3671561 6067391 EcolC_3346 Escherichia coli ATCC 8739 insertion element protein YP_001726293.1 3670864 R 481805 CDS YP_001726294.1 170021340 6067398 complement(3671754..3672047) 1 NC_010468.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: sfv:SFV_0298 hypothetical protein; putative antitoxin of the YafO-YafN toxin-antitoxin system 3672047 6067398 EcolC_3348 Escherichia coli ATCC 8739 putative antitoxin of the YafO-YafN toxin-antitoxin system YP_001726294.1 3671754 R 481805 CDS YP_001726295.1 170021341 6067406 complement(3672099..3673154) 1 NC_010468.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 3673154 6067406 EcolC_3349 Escherichia coli ATCC 8739 DNA polymerase IV YP_001726295.1 3672099 R 481805 CDS YP_001726296.1 170021342 6067409 complement(3673225..3674148) 1 NC_010468.1 PFAM: OmpA/MotB domain protein; KEGG: sdy:SDY_0484 putative motility protein; hypothetical protein 3674148 6067409 EcolC_3350 Escherichia coli ATCC 8739 hypothetical protein YP_001726296.1 3673225 R 481805 CDS YP_001726297.1 170021343 6067410 complement(3674151..3675014) 1 NC_010468.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 3675014 6067410 EcolC_3351 Escherichia coli ATCC 8739 flagellar motor protein MotA YP_001726297.1 3674151 R 481805 CDS YP_001726298.1 170021344 6067414 complement(3675027..3675743) 1 NC_010468.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 3675743 6067414 EcolC_3352 Escherichia coli ATCC 8739 flagellar biosynthesis sigma factor YP_001726298.1 3675027 R 481805 CDS YP_001726299.1 170021345 6067429 complement(3675763..3676230) 1 NC_010468.1 PFAM: flagellar basal body-associated protein FliL; KEGG: cvi:CV_2991 hypothetical protein; flagellar basal body-associated protein FliL 3676230 6067429 EcolC_3353 Escherichia coli ATCC 8739 flagellar basal body-associated protein FliL YP_001726299.1 3675763 R 481805 CDS YP_001726300.1 170021346 6067432 complement(3676238..3677299) 1 NC_010468.1 PFAM: flagellar hook-length control protein; KEGG: cko:CKO_02859 hypothetical protein; flagellar hook-length control protein 3677299 6067432 EcolC_3354 Escherichia coli ATCC 8739 flagellar hook-length control protein YP_001726300.1 3676238 R 481805 CDS YP_001726301.1 170021347 6067434 complement(3677296..3677607) 1 NC_010468.1 hypothetical protein 3677607 6067434 EcolC_3355 Escherichia coli ATCC 8739 hypothetical protein YP_001726301.1 3677296 R 481805 CDS YP_001726302.1 170021348 6067437 complement(3677612..3678004) 1 NC_010468.1 PFAM: flagellar protein FliS; KEGG: cko:CKO_02862 hypothetical protein; flagellar protein FliS 3678004 6067437 EcolC_3356 Escherichia coli ATCC 8739 flagellar protein FliS YP_001726302.1 3677612 R 481805 CDS YP_001726303.1 170021349 6067442 complement(3678027..3679343) 1 NC_010468.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: vha:VIBHAR_04956 flagellar capping protein; flagellar hook-associated 2 domain-containing protein 3679343 6067442 EcolC_3357 Escherichia coli ATCC 8739 flagellar hook-associated 2 domain-containing protein YP_001726303.1 3678027 R 481805 CDS YP_001726304.1 170021350 6067022 complement(3679595..3680509) 1 NC_010468.1 PFAM: flagellin domain protein; KEGG: pmy:Pmen_0196 flagellin domain protein; flagellin domain-containing protein 3680509 6067022 EcolC_3358 Escherichia coli ATCC 8739 flagellin domain-containing protein YP_001726304.1 3679595 R 481805 CDS YP_001726305.1 170021351 6067445 3680995..3681837 1 NC_010468.1 PFAM: transcriptional regulator domain protein; KEGG: cko:CKO_02869 hypothetical protein; transcriptional regulator CadC 3681837 6067445 EcolC_3359 Escherichia coli ATCC 8739 transcriptional regulator CadC YP_001726305.1 3680995 D 481805 CDS YP_001726306.1 170021352 6067455 complement(3681896..3682873) 1 NC_010468.1 KEGG: cko:CKO_02871 hypothetical protein; hypothetical protein 3682873 6067455 EcolC_3360 Escherichia coli ATCC 8739 hypothetical protein YP_001726306.1 3681896 R 481805 CDS YP_001726307.1 170021353 6064975 complement(3682890..3683819) 1 NC_010468.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: pmy:Pmen_0216 flagellar hook-associated protein 3; flagellar hook-associated protein 3 3683819 6064975 EcolC_3361 Escherichia coli ATCC 8739 flagellar hook-associated protein 3 YP_001726307.1 3682890 R 481805 CDS YP_001726308.1 170021354 6067459 complement(3683834..3685210) 1 NC_010468.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cko:CKO_02873 hypothetical protein; flagellar hook-associated protein FlgK 3685210 6067459 EcolC_3362 Escherichia coli ATCC 8739 flagellar hook-associated protein FlgK YP_001726308.1 3683834 R 481805 CDS YP_001726309.1 170021355 6067463 complement(3685400..3685699) 1 NC_010468.1 KEGG: yps:YPTB3332 putative flagellar protein; rod binding protein-like protein 3685699 6067463 EcolC_3363 Escherichia coli ATCC 8739 rod binding protein-like protein YP_001726309.1 3685400 R 481805 CDS YP_001726310.1 170021356 6067464 complement(3685699..3686799) 1 NC_010468.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 3686799 flgI 6067464 flgI Escherichia coli ATCC 8739 flagellar basal body P-ring protein YP_001726310.1 3685699 R 481805 CDS YP_001726311.1 170021357 6066213 complement(3686814..3687479) 1 NC_010468.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH; flagellar basal body L-ring protein 3687479 flgH 6066213 flgH Escherichia coli ATCC 8739 flagellar basal body L-ring protein YP_001726311.1 3686814 R 481805 CDS YP_001726312.1 170021358 6067467 complement(3687682..3688467) 1 NC_010468.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 3688467 flgG 6067467 flgG Escherichia coli ATCC 8739 flagellar basal body rod protein FlgG YP_001726312.1 3687682 R 481805 CDS YP_001726313.1 170021359 6067471 complement(3688546..3689283) 1 NC_010468.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 3689283 flgF 6067471 flgF Escherichia coli ATCC 8739 flagellar basal body rod protein FlgF YP_001726313.1 3688546 R 481805 CDS YP_001726314.1 170021360 6064903 complement(3689283..3690485) 1 NC_010468.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: pmy:Pmen_0209 flagellar basal body FlaE domain protein; flagellar basal body FlaE domain-containing protein 3690485 6064903 EcolC_3368 Escherichia coli ATCC 8739 flagellar basal body FlaE domain-containing protein YP_001726314.1 3689283 R 481805 CDS YP_001726315.1 170021361 6067477 complement(3690628..3691341) 1 NC_010468.1 PFAM: flagellar hook capping protein; KEGG: cko:CKO_02880 hypothetical protein; flagellar hook capping protein 3691341 6067477 EcolC_3369 Escherichia coli ATCC 8739 flagellar hook capping protein YP_001726315.1 3690628 R 481805 CDS YP_001726316.1 170021362 6067494 complement(3691341..3691772) 1 NC_010468.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar basal body rod protein FlgC 3691772 flgC 6067494 flgC Escherichia coli ATCC 8739 flagellar basal body rod protein FlgC YP_001726316.1 3691341 R 481805 CDS YP_001726317.1 170021363 6066135 complement(3691775..3692110) 1 NC_010468.1 TIGRFAM: flagellar basal-body rod protein FlgB; KEGG: cko:CKO_02882 hypothetical protein; flagellar basal-body rod protein FlgB 3692110 6066135 EcolC_3371 Escherichia coli ATCC 8739 flagellar basal-body rod protein FlgB YP_001726317.1 3691775 R 481805 CDS YP_001726318.1 170021364 6067497 3692192..3692929 1 NC_010468.1 TIGRFAM: flagella basal body P-ring formation protein FlgA; PFAM: SAF domain protein; KEGG: cko:CKO_02883 hypothetical protein; flagella basal body P-ring formation protein FlgA 3692929 6067497 EcolC_3372 Escherichia coli ATCC 8739 flagella basal body P-ring formation protein FlgA YP_001726318.1 3692192 D 481805 CDS YP_001726319.1 170021365 6067500 3693010..3693288 1 NC_010468.1 PFAM: Anti-sigma-28 factor FlgM family protein; anti-sigma-28 factor FlgM 3693288 6067500 EcolC_3373 Escherichia coli ATCC 8739 anti-sigma-28 factor FlgM YP_001726319.1 3693010 D 481805 CDS YP_001726320.1 170021366 6067511 3693301..3693729 1 NC_010468.1 KEGG: cko:CKO_02886 hypothetical protein; hypothetical protein 3693729 6067511 EcolC_3374 Escherichia coli ATCC 8739 hypothetical protein YP_001726320.1 3693301 D 481805 CDS YP_001726321.1 170021367 6067512 3693856..3694785 1 NC_010468.1 KEGG: cko:CKO_02891 hypothetical protein; hypothetical protein 3694785 6067512 EcolC_3375 Escherichia coli ATCC 8739 hypothetical protein YP_001726321.1 3693856 D 481805 CDS YP_001726322.1 170021368 6067521 3694964..3697408 1 NC_010468.1 PFAM: glycosyl transferase family 2; KEGG: cko:CKO_02892 hypothetical protein; glycosyl transferase family protein 3697408 6067521 EcolC_3376 Escherichia coli ATCC 8739 glycosyl transferase family protein YP_001726322.1 3694964 D 481805 CDS YP_001726323.1 170021369 6067529 complement(3697526..3697921) 1 NC_010468.1 TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: nca:Noca_1691 cytidyltransferase-related domain; cytidyltransferase-like protein 3697921 6067529 EcolC_3377 Escherichia coli ATCC 8739 cytidyltransferase-like protein YP_001726323.1 3697526 R 481805 CDS YP_001726324.1 170021370 6067540 complement(3697924..3698358) 1 NC_010468.1 TIGRFAM: flagellar export protein FliJ; KEGG: cko:CKO_02893 hypothetical protein; flagellar export protein FliJ 3698358 6067540 EcolC_3378 Escherichia coli ATCC 8739 flagellar export protein FliJ YP_001726324.1 3697924 R 481805 CDS YP_001726325.1 170021371 6067543 complement(3698361..3699698) 1 NC_010468.1 KEGG: cko:CKO_02894 hypothetical protein; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase; FliI/YscN family ATPase 3699698 6067543 EcolC_3379 Escherichia coli ATCC 8739 FliI/YscN family ATPase YP_001726325.1 3698361 R 481805 CDS YP_001726326.1 170021372 6067562 complement(3699691..3700401) 1 NC_010468.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 3700401 fliH 6067562 fliH Escherichia coli ATCC 8739 flagellar assembly protein H YP_001726326.1 3699691 R 481805 CDS YP_001726327.1 170021373 6067565 complement(3700405..3701415) 1 NC_010468.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 3701415 fliG 6067565 fliG Escherichia coli ATCC 8739 flagellar motor switch protein G YP_001726327.1 3700405 R 481805 CDS YP_001726328.1 170021374 6067566 complement(3701393..3703039) 1 NC_010468.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar MS-ring protein 3703039 fliF 6067566 fliF Escherichia coli ATCC 8739 flagellar MS-ring protein YP_001726328.1 3701393 R 481805 CDS YP_001726329.1 170021375 6067567 complement(3703044..3703385) 1 NC_010468.1 PFAM: flagellar hook-basal body complex protein FliE; KEGG: vpa:VPA1537 putative flagellar hook-basal body complex protein; flagellar hook-basal body complex protein FliE 3703385 6067567 EcolC_3383 Escherichia coli ATCC 8739 flagellar hook-basal body complex protein FliE YP_001726329.1 3703044 R 481805 CDS YP_001726330.1 170021376 6067568 complement(3703400..3704386) 1 NC_010468.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; KEGG: ypi:YpsIP31758_0629 sigma-54 dependent transcriptional regulator; putative sigma-54 specific transcriptional regulator 3704386 6067568 EcolC_3384 Escherichia coli ATCC 8739 putative sigma-54 specific transcriptional regulator YP_001726330.1 3703400 R 481805 CDS YP_001726331.1 170021377 6067577 3704773..3705624 1 NC_010468.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: cko:CKO_02900 hypothetical protein; surface presentation of antigens (SPOA) protein 3705624 6067577 EcolC_3385 Escherichia coli ATCC 8739 surface presentation of antigens (SPOA) protein YP_001726331.1 3704773 D 481805 CDS YP_001726332.1 170021378 6067581 3705617..3705988 1 NC_010468.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: cko:CKO_02901 hypothetical protein; surface presentation of antigens (SPOA) protein 3705988 6067581 EcolC_3386 Escherichia coli ATCC 8739 surface presentation of antigens (SPOA) protein YP_001726332.1 3705617 D 481805 CDS YP_001726333.1 170021379 6067586 3705985..3706737 1 NC_010468.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 3706737 fliP 6067586 fliP Escherichia coli ATCC 8739 flagellar biosynthesis protein FliP YP_001726333.1 3705985 D 481805 CDS YP_001726334.1 170021380 6067607 3706740..3707012 1 NC_010468.1 PFAM: export protein FliQ family 3; KEGG: yps:YPTB3354 putative flagellar assembly/export protein, fliQ; export protein FliQ 3707012 6067607 EcolC_3388 Escherichia coli ATCC 8739 export protein FliQ YP_001726334.1 3706740 D 481805 CDS YP_001726335.1 170021381 6067608 3707014..3707796 1 NC_010468.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: cko:CKO_02904 hypothetical protein; flagellar biosynthetic protein FliR 3707796 6067608 EcolC_3389 Escherichia coli ATCC 8739 flagellar biosynthetic protein FliR YP_001726335.1 3707014 D 481805 CDS YP_001726336.1 170021382 6067612 3707786..3708925 1 NC_010468.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 3708925 flhB 6067612 flhB Escherichia coli ATCC 8739 flagellar biosynthesis protein FlhB YP_001726336.1 3707786 D 481805 CDS YP_001726337.1 170021383 6067614 3708909..3711002 1 NC_010468.1 PFAM: type III secretion FHIPEP protein; KEGG: ssn:SSON_0273 flagellar biosynthesis; type III secretion FHIPEP protein 3711002 6067614 EcolC_3391 Escherichia coli ATCC 8739 type III secretion FHIPEP protein YP_001726337.1 3708909 D 481805 CDS YP_001726338.1 170021384 6067618 complement(3711218..3711715) 1 NC_010468.1 KEGG: ssn:SSON_0271 hypothetical protein; hypothetical protein 3711715 6067618 EcolC_3392 Escherichia coli ATCC 8739 hypothetical protein YP_001726338.1 3711218 R 481805 CDS YP_001726339.1 170021385 6067623 complement(3711891..3712517) 1 NC_010468.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_0269 putative lipoprotein; NLP/P60 protein 3712517 6067623 EcolC_3393 Escherichia coli ATCC 8739 NLP/P60 protein YP_001726339.1 3711891 R 481805 CDS YP_001726340.1 170021386 6067634 3712850..3713110 1 NC_010468.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: ssn:SSON_0268 damage-inducible protein J; addiction module antitoxin 3713110 6067634 EcolC_3394 Escherichia coli ATCC 8739 addiction module antitoxin YP_001726340.1 3712850 D 481805 CDS YP_001726341.1 170021387 6067638 3713113..3713391 1 NC_010468.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sdy:SDY_0251 hypothetical protein; addiction module antitoxin 3713391 6067638 EcolC_3395 Escherichia coli ATCC 8739 addiction module antitoxin YP_001726341.1 3713113 D 481805 CDS YP_001726342.1 170021388 6067655 3713547..3714287 1 NC_010468.1 PFAM: protein of unknown function DUF949; KEGG: sdy:SDY_0250 hypothetical protein; hypothetical protein 3714287 6067655 EcolC_3396 Escherichia coli ATCC 8739 hypothetical protein YP_001726342.1 3713547 D 481805 CDS YP_001726343.1 170021389 6067660 complement(3714258..3715025) 1 NC_010468.1 PFAM: glutamine amidotransferase class-II; KEGG: sdy:SDY_0249 putative amidotransferase; glutamine amidotransferase 3715025 6067660 EcolC_3397 Escherichia coli ATCC 8739 glutamine amidotransferase YP_001726343.1 3714258 R 481805 CDS YP_001726344.1 170021390 6067666 complement(3715231..3715809) 1 NC_010468.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 3715809 gmhA 6067666 gmhA Escherichia coli ATCC 8739 phosphoheptose isomerase YP_001726344.1 3715231 R 481805 CDS YP_001726345.1 170021391 6067673 3716049..3718493 1 NC_010468.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 3718493 fadE 6067673 fadE Escherichia coli ATCC 8739 acyl-CoA dehydrogenase YP_001726345.1 3716049 D 481805 CDS YP_001726346.1 170021392 6067676 complement(3718536..3719009) 1 NC_010468.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 3719009 6067676 EcolC_3400 Escherichia coli ATCC 8739 C-lysozyme inhibitor YP_001726346.1 3718536 R 481805 CDS YP_001726347.1 170021393 6067679 3719163..3719933 1 NC_010468.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbo:SBO_0208 putative amidase-type enzyme; hypothetical protein 3719933 6067679 EcolC_3401 Escherichia coli ATCC 8739 hypothetical protein YP_001726347.1 3719163 D 481805 CDS YP_001726348.1 170021394 6067701 complement(3722286..3722861) 1 NC_010468.1 KEGG: dac:Daci_2522 conserved hypothetical protein; hypothetical protein 3722861 6067701 EcolC_3404 Escherichia coli ATCC 8739 hypothetical protein YP_001726348.1 3722286 R 481805 CDS YP_001726349.1 170021395 6067702 3723179..3723463 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 3723463 6067702 EcolC_3405 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001726349.1 3723179 D 481805 CDS YP_001726350.1 170021396 6067703 3723505..3724314 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family; integrase catalytic subunit 3724314 6067703 EcolC_3406 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001726350.1 3723505 D 481805 CDS YP_001726351.1 170021397 6067704 3724377..3724733 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_4359 ISEhe3 orfA; transposase IS3/IS911 family protein 3724733 6067704 EcolC_3407 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001726351.1 3724377 D 481805 CDS YP_001726352.1 170021398 6067712 3724690..3725652 1 NC_010468.1 KEGG: bxe:Bxe_C0741 putative transposase IS30; putative transposase IS30 3725652 6067712 EcolC_3408 Escherichia coli ATCC 8739 putative transposase IS30 YP_001726352.1 3724690 D 481805 CDS YP_001726353.1 170021399 6067719 3725926..3726744 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2; integrase catalytic subunit 3726744 6067719 EcolC_3409 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001726353.1 3725926 D 481805 CDS YP_001726354.1 170021400 6067732 complement(3726857..3727291) 1 NC_010468.1 KEGG: kpn:KPN_pKPN3p05933 probable copper-binding protein; putative copper-binding protein 3727291 6067732 EcolC_3410 Escherichia coli ATCC 8739 putative copper-binding protein YP_001726354.1 3726857 R 481805 CDS YP_001726355.1 170021401 6067733 complement(3727509..3728909) 1 NC_010468.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: esa:ESA_04254 hypothetical protein; heavy metal sensor signal transduction histidine kinase 3728909 6067733 EcolC_3411 Escherichia coli ATCC 8739 heavy metal sensor signal transduction histidine kinase YP_001726355.1 3727509 R 481805 CDS YP_001726356.1 170021402 6067738 complement(3728906..3729586) 1 NC_010468.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: kpn:KPN_pKPN3p05937 transcriptional regulatory protein PcoR; two component heavy metal response transcriptional regulator 3729586 6067738 EcolC_3412 Escherichia coli ATCC 8739 two component heavy metal response transcriptional regulator YP_001726356.1 3728906 R 481805 CDS YP_001726357.1 170021403 6066087 complement(3729641..3730570) 1 NC_010468.1 PFAM: copper resistance D domain protein; KEGG: kpn:KPN_pKPN3p05938 copper resistant protein PcoD; copper resistance D domain-containing protein 3730570 6066087 EcolC_3413 Escherichia coli ATCC 8739 copper resistance D domain-containing protein YP_001726357.1 3729641 R 481805 CDS YP_001726358.1 170021404 6067751 complement(3730575..3730955) 1 NC_010468.1 PFAM: copper resistance protein CopC; KEGG: kpn:KPN_pKPN3p05939 copper resistant protein PcoC; copper resistance protein CopC 3730955 6067751 EcolC_3414 Escherichia coli ATCC 8739 copper resistance protein CopC YP_001726358.1 3730575 R 481805 CDS YP_001726359.1 170021405 6067753 complement(3730995..3731891) 1 NC_010468.1 PFAM: copper resistance B precursor; KEGG: kpn:KPN_pKPN3p05940 copper resistant protein PcoB; copper resistance B 3731891 6067753 EcolC_3415 Escherichia coli ATCC 8739 copper resistance B YP_001726359.1 3730995 R 481805 CDS YP_001726360.1 170021406 6067764 complement(3731891..3733708) 1 NC_010468.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: kpn:KPN_pKPN3p05941 copper resistant protein PcoA; CopA family copper resistance protein 3733708 6067764 EcolC_3416 Escherichia coli ATCC 8739 CopA family copper resistance protein YP_001726360.1 3731891 R 481805 CDS YP_001726361.1 170021407 6067769 3733943..3734392 1 NC_010468.1 KEGG: shn:Shewana3_4304 hypothetical protein; hypothetical protein 3734392 6067769 EcolC_3417 Escherichia coli ATCC 8739 hypothetical protein YP_001726361.1 3733943 D 481805 CDS YP_001726362.1 170021408 6067773 3734681..3735418 1 NC_010468.1 PFAM: peptidase M23B; KEGG: shn:Shewana3_4303 peptidase M23B; peptidase M23B 3735418 6067773 EcolC_3418 Escherichia coli ATCC 8739 peptidase M23B YP_001726362.1 3734681 D 481805 CDS YP_001726363.1 170021409 6067789 complement(3735452..3735649) 1 NC_010468.1 KEGG: esa:ESA_04246 hypothetical protein; hypothetical protein 3735649 6067789 EcolC_3419 Escherichia coli ATCC 8739 hypothetical protein YP_001726363.1 3735452 R 481805 CDS YP_001726364.1 170021410 6067798 complement(3735690..3738137) 1 NC_010468.1 KEGG: spc:Sputcn32_0264 heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein; heavy metal translocating P-type ATPase 3738137 6067798 EcolC_3420 Escherichia coli ATCC 8739 heavy metal translocating P-type ATPase YP_001726364.1 3735690 R 481805 CDS YP_001726365.1 170021411 6067820 complement(3738264..3738704) 1 NC_010468.1 PFAM: protein of unknown function DUF411; KEGG: kpn:KPN_pKPN3p05946 exported protein (silver resistance); hypothetical protein 3738704 6067820 EcolC_3421 Escherichia coli ATCC 8739 hypothetical protein YP_001726365.1 3738264 R 481805 CDS YP_001726366.1 170021412 6067821 complement(3738791..3741937) 1 NC_010468.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: esa:ESA_04242 hypothetical protein; CzcA family heavy metal efflux protein 3741937 6067821 EcolC_3422 Escherichia coli ATCC 8739 CzcA family heavy metal efflux protein YP_001726366.1 3738791 R 481805 CDS YP_001726367.1 170021413 6067827 complement(3741948..3743240) 1 NC_010468.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 3743240 6067827 EcolC_3423 Escherichia coli ATCC 8739 copper/silver efflux system membrane fusion protein CusB YP_001726367.1 3741948 R 481805 CDS YP_001726368.1 170021414 6067829 complement(3743354..3743707) 1 NC_010468.1 KEGG: spc:Sputcn32_0260 periplasmic copper-binding protein; copper-binding protein 3743707 6067829 EcolC_3424 Escherichia coli ATCC 8739 copper-binding protein YP_001726368.1 3743354 R 481805 CDS YP_001726369.1 170021415 6067839 complement(3743736..3745121) 1 NC_010468.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 3745121 6067839 EcolC_3425 Escherichia coli ATCC 8739 copper/silver efflux system outer membrane protein CusC YP_001726369.1 3743736 R 481805 CDS YP_001726370.1 170021416 6067858 3745311..3745991 1 NC_010468.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 3745991 6067858 EcolC_3426 Escherichia coli ATCC 8739 DNA-binding transcriptional activator CusR YP_001726370.1 3745311 D 481805 CDS YP_001726371.1 170021417 6067860 3745984..3747459 1 NC_010468.1 KEGG: esa:ESA_04237 hypothetical protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; sensor kinase CusS 3747459 6067860 EcolC_3427 Escherichia coli ATCC 8739 sensor kinase CusS YP_001726371.1 3745984 D 481805 CDS YP_001726372.1 170021418 6067865 3747710..3748141 1 NC_010468.1 KEGG: kpn:KPN_pKPN3p05952 silver binding protein precursor SilE; silver binding protein SilE 3748141 6067865 EcolC_3428 Escherichia coli ATCC 8739 silver binding protein SilE YP_001726372.1 3747710 D 481805 CDS YP_001726373.1 170021419 6067875 3749726..3750076 1 NC_010468.1 PFAM: protein of unknown function DUF305; KEGG: esa:ESA_04235 hypothetical protein; hypothetical protein 3750076 6067875 EcolC_3430 Escherichia coli ATCC 8739 hypothetical protein YP_001726373.1 3749726 D 481805 CDS YP_001726374.1 170021420 6067887 complement(3751949..3752605) 1 NC_010468.1 PFAM: putative transposase YhgA family protein; KEGG: stm:PSLT051 putative cytoplasmic protein; putative transposase YhgA family protein 3752605 6067887 EcolC_3432 Escherichia coli ATCC 8739 putative transposase YhgA family protein YP_001726374.1 3751949 R 481805 CDS YP_001726375.1 170021421 6067889 3752875..3753750 1 NC_010468.1 PFAM: GTP-binding protein HSR1-related; KEGG: ypi:YpsIP31758_0759 putative GTPase; HSR1-like GTP-binding protein 3753750 6067889 EcolC_3433 Escherichia coli ATCC 8739 HSR1-like GTP-binding protein YP_001726375.1 3752875 D 481805 CDS YP_001726376.1 170021422 6067890 3754011..3754724 1 NC_010468.1 KEGG: ypi:YpsIP31758_0758 transcriptional regulator; transcriptional regulator 3754724 6067890 EcolC_3434 Escherichia coli ATCC 8739 transcriptional regulator YP_001726376.1 3754011 D 481805 CDS YP_001726377.1 170021423 6067891 3754721..3755356 1 NC_010468.1 KEGG: ypi:YpsIP31758_0757 hypothetical protein; hypothetical protein 3755356 6067891 EcolC_3435 Escherichia coli ATCC 8739 hypothetical protein YP_001726377.1 3754721 D 481805 CDS YP_001726378.1 170021424 6067896 3755392..3755844 1 NC_010468.1 hypothetical protein 3755844 6067896 EcolC_3436 Escherichia coli ATCC 8739 hypothetical protein YP_001726378.1 3755392 D 481805 CDS YP_001726379.1 170021425 6067900 3755841..3756293 1 NC_010468.1 hypothetical protein 3756293 6067900 EcolC_3437 Escherichia coli ATCC 8739 hypothetical protein YP_001726379.1 3755841 D 481805 CDS YP_001726380.1 170021426 6067902 3756356..3756898 1 NC_010468.1 KEGG: ypi:YpsIP31758_0756 hypothetical protein; hypothetical protein 3756898 6067902 EcolC_3438 Escherichia coli ATCC 8739 hypothetical protein YP_001726380.1 3756356 D 481805 CDS YP_001726381.1 170021427 6067903 3756957..3757409 1 NC_010468.1 KEGG: sfx:S3197 hypothetical protein; hypothetical protein 3757409 6067903 EcolC_3439 Escherichia coli ATCC 8739 hypothetical protein YP_001726381.1 3756957 D 481805 CDS YP_001726382.1 170021428 6067918 3757486..3757719 1 NC_010468.1 KEGG: ypp:YPDSF_4148 hypothetical protein; hypothetical protein 3757719 6067918 EcolC_3440 Escherichia coli ATCC 8739 hypothetical protein YP_001726382.1 3757486 D 481805 CDS YP_001726383.1 170021429 6067923 3757839..3758657 1 NC_010468.1 PFAM: protein of unknown function DUF932; KEGG: sfx:S3199 hypothetical protein; hypothetical protein 3758657 6067923 EcolC_3441 Escherichia coli ATCC 8739 hypothetical protein YP_001726383.1 3757839 D 481805 CDS YP_001726384.1 170021430 6067926 3758925..3759395 1 NC_010468.1 PFAM: Antirestriction protein; KEGG: sdy:SDY_4589 hypothetical protein; antirestriction protein 3759395 6067926 EcolC_3442 Escherichia coli ATCC 8739 antirestriction protein YP_001726384.1 3758925 D 481805 CDS YP_001726385.1 170021431 6067928 3759407..3759886 1 NC_010468.1 PFAM: DNA repair protein RadC; KEGG: yps:YPTB3868 hypothetical protein; DNA repair protein RadC 3759886 6067928 EcolC_3443 Escherichia coli ATCC 8739 DNA repair protein RadC YP_001726385.1 3759407 D 481805 CDS YP_001726386.1 170021432 6067929 3759907..3760128 1 NC_010468.1 PFAM: protein of unknown function DUF987; KEGG: sfx:S3202 hypothetical protein; hypothetical protein 3760128 6067929 EcolC_3444 Escherichia coli ATCC 8739 hypothetical protein YP_001726386.1 3759907 D 481805 CDS YP_001726387.1 170021433 6067931 3760152..3760511 1 NC_010468.1 PFAM: YagBYeeUYfjZ family protein; KEGG: sfx:S3203 putative structural protein; hypothetical protein 3760511 6067931 EcolC_3445 Escherichia coli ATCC 8739 hypothetical protein YP_001726387.1 3760152 D 481805 CDS YP_001726388.1 170021434 6067939 3760562..3760939 1 NC_010468.1 PFAM: protein of unknown function DUF1219; KEGG: sdy:SDY_1009 hypothetical protein; hypothetical protein 3760939 6067939 EcolC_3446 Escherichia coli ATCC 8739 hypothetical protein YP_001726388.1 3760562 D 481805 CDS YP_001726389.1 170021435 6067942 3760936..3761427 1 NC_010468.1 KEGG: sdy:SDY_1008 hypothetical protein; hypothetical protein 3761427 6067942 EcolC_3447 Escherichia coli ATCC 8739 hypothetical protein YP_001726389.1 3760936 D 481805 CDS YP_001726390.1 170021436 6067946 3761459..3761662 1 NC_010468.1 PFAM: protein of unknown function DUF957; KEGG: sfl:SF3001 hypothetical protein; hypothetical protein 3761662 6067946 EcolC_3448 Escherichia coli ATCC 8739 hypothetical protein YP_001726390.1 3761459 D 481805 CDS YP_001726391.1 170021437 6067968 complement(3762929..3763669) 1 NC_010468.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 3763669 6067968 EcolC_3450 Escherichia coli ATCC 8739 DNA polymerase III subunit epsilon YP_001726391.1 3762929 R 481805 CDS YP_001726392.1 170021438 6067989 3763725..3764192 1 NC_010468.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 3764192 rnhA 6067989 rnhA Escherichia coli ATCC 8739 ribonuclease H YP_001726392.1 3763725 D 481805 CDS YP_001726393.1 170021439 6067994 complement(3764189..3764911) 1 NC_010468.1 PFAM: Methyltransferase type 11; KEGG: ssn:SSON_0227 hypothetical protein; type 11 methyltransferase 3764911 6067994 EcolC_3452 Escherichia coli ATCC 8739 type 11 methyltransferase YP_001726393.1 3764189 R 481805 CDS YP_001726394.1 170021440 6067997 3764945..3765700 1 NC_010468.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 3765700 6067997 EcolC_3453 Escherichia coli ATCC 8739 hydroxyacylglutathione hydrolase YP_001726394.1 3764945 D 481805 CDS YP_001726395.1 170021441 6067999 3765772..3767130 1 NC_010468.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 3767130 mltD 6067999 mltD Escherichia coli ATCC 8739 membrane-bound lytic murein transglycosylase D YP_001726395.1 3765772 D 481805 CDS YP_001726396.1 170021442 6068017 complement(3767178..3767801) 1 NC_010468.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ssn:SSON_0224 putative biotin synthesis protein; type 11 methyltransferase 3767801 6068017 EcolC_3455 Escherichia coli ATCC 8739 type 11 methyltransferase YP_001726396.1 3767178 R 481805 CDS YP_001726397.1 170021443 6068025 complement(3767805..3768605) 1 NC_010468.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sbo:SBO_0198 hypothetical protein; hypothetical protein 3768605 6068025 EcolC_3456 Escherichia coli ATCC 8739 hypothetical protein YP_001726397.1 3767805 R 481805 CDS YP_001726398.1 170021444 6068027 3768846..3769760 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_0222 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 3769760 6068027 EcolC_3457 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001726398.1 3768846 D 481805 CDS YP_001726399.1 170021445 6068048 complement(3769757..3770560) 1 NC_010468.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 3770560 dkgB 6068048 dkgB Escherichia coli ATCC 8739 2,5-diketo-D-gluconate reductase B YP_001726399.1 3769757 R 481805 CDS YP_001726400.1 170021446 6068154 complement(3776414..3776986) 1 NC_010468.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 3776986 6068154 EcolC_3459 Escherichia coli ATCC 8739 D,D-heptose 1,7-bisphosphate phosphatase YP_001726400.1 3776414 R 481805 CDS YP_001726401.1 170021447 6068159 3777174..3778205 1 NC_010468.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 3778205 metN 6068159 metN Escherichia coli ATCC 8739 DL-methionine transporter ATP-binding subunit YP_001726401.1 3777174 D 481805 CDS YP_001726402.1 170021448 6068161 3778198..3778851 1 NC_010468.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 3778851 6068161 EcolC_3461 Escherichia coli ATCC 8739 DL-methionine transporter permease YP_001726402.1 3778198 D 481805 CDS YP_001726403.1 170021449 6068182 3778891..3779706 1 NC_010468.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sbo:SBO_0186 putative lipoprotein; DL-methionine transporter substrate-binding subunit 3779706 metQ 6068182 metQ Escherichia coli ATCC 8739 DL-methionine transporter substrate-binding subunit YP_001726403.1 3778891 D 481805 CDS YP_001726404.1 170021450 6068187 3779824..3780228 1 NC_010468.1 KEGG: sdy:SDY_0215 regulator in colanic acid synthesis; outer membrane lipoprotein 3780228 rcsF 6068187 rcsF Escherichia coli ATCC 8739 outer membrane lipoprotein YP_001726404.1 3779824 D 481805 CDS YP_001726405.1 170021451 6068188 3780225..3780932 1 NC_010468.1 PFAM: protein of unknown function UPF0066; KEGG: ssn:SSON_0209 hypothetical protein; hypothetical protein 3780932 6068188 EcolC_3464 Escherichia coli ATCC 8739 hypothetical protein YP_001726405.1 3780225 D 481805 CDS YP_001726406.1 170021452 6068198 3781044..3782762 1 NC_010468.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3782762 6068198 EcolC_3465 Escherichia coli ATCC 8739 prolyl-tRNA synthetase YP_001726406.1 3781044 D 481805 CDS YP_001726407.1 170021453 6068203 3782816..3783640 1 NC_010468.1 KEGG: ssn:SSON_0207 hypothetical protein; hypothetical protein 3783640 6068203 EcolC_3466 Escherichia coli ATCC 8739 hypothetical protein YP_001726407.1 3782816 D 481805 CDS YP_001726408.1 170021454 6068207 complement(3783814..3784524) 1 NC_010468.1 PFAM: copper resistance lipoprotein NlpE; KEGG: ssn:SSON_0206 copper homeostasis protein; lipoprotein involved with copper homeostasis and adhesion 3784524 6068207 EcolC_3467 Escherichia coli ATCC 8739 lipoprotein involved with copper homeostasis and adhesion YP_001726408.1 3783814 R 481805 CDS YP_001726409.1 170021455 6068210 complement(3784538..3784960) 1 NC_010468.1 PFAM: Class I peptide chain release factor; KEGG: sbo:SBO_0180 hypothetical protein; peptidyl-tRNA hydrolase domain-containing protein 3784960 6068210 EcolC_3468 Escherichia coli ATCC 8739 peptidyl-tRNA hydrolase domain-containing protein YP_001726409.1 3784538 R 481805 CDS YP_001726410.1 170021456 6068225 complement(3784957..3785502) 1 NC_010468.1 PFAM: YaeQ family protein; KEGG: sbo:SBO_0179 hypothetical protein; YaeQ family protein 3785502 6068225 EcolC_3469 Escherichia coli ATCC 8739 YaeQ family protein YP_001726410.1 3784957 R 481805 CDS YP_001726411.1 170021457 6068244 3785668..3785868 1 NC_010468.1 PFAM: protein of unknown function UPF0253; KEGG: sdy:SDY_0208 putative cytoplasmic protein; hypothetical protein 3785868 6068244 EcolC_3470 Escherichia coli ATCC 8739 hypothetical protein YP_001726411.1 3785668 D 481805 CDS YP_001726412.1 170021458 6068249 3785855..3786115 1 NC_010468.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 3786115 6068249 EcolC_3471 Escherichia coli ATCC 8739 Rho-binding antiterminator YP_001726412.1 3785855 D 481805 CDS YP_001726413.1 170021459 6068250 complement(3786164..3787462) 1 NC_010468.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 3787462 tilS 6068250 tilS Escherichia coli ATCC 8739 tRNA(Ile)-lysidine synthetase YP_001726413.1 3786164 R 481805 CDS YP_001726414.1 170021460 6068259 complement(3787527..3787916) 1 NC_010468.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sbo:SBO_0175 hypothetical protein; hypothetical protein 3787916 6068259 EcolC_3473 Escherichia coli ATCC 8739 hypothetical protein YP_001726414.1 3787527 R 481805 CDS YP_001726415.1 170021461 6068263 complement(3787973..3790114) 1 NC_010468.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ssn:SSON_0199 lysine decarboxylase 2, constitutive; lysine decarboxylase 3790114 6068263 EcolC_3474 Escherichia coli ATCC 8739 lysine decarboxylase YP_001726415.1 3787973 R 481805 CDS YP_001726416.1 170021462 6068277 complement(3790213..3791172) 1 NC_010468.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 3791172 6068277 EcolC_3475 Escherichia coli ATCC 8739 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001726416.1 3790213 R 481805 CDS YP_001726417.1 170021463 6068282 complement(3791185..3794667) 1 NC_010468.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 3794667 dnaE 6068282 dnaE Escherichia coli ATCC 8739 DNA polymerase III subunit alpha YP_001726417.1 3791185 R 481805 CDS YP_001726418.1 170021464 6068291 complement(3794704..3795300) 1 NC_010468.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 3795300 rnhB 6068291 rnhB Escherichia coli ATCC 8739 ribonuclease HII YP_001726418.1 3794704 R 481805 CDS YP_001726419.1 170021465 6068300 complement(3795297..3796445) 1 NC_010468.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 3796445 lpxB 6068300 lpxB Escherichia coli ATCC 8739 lipid-A-disaccharide synthase YP_001726419.1 3795297 R 481805 CDS YP_001726420.1 170021466 6068311 complement(3796445..3797233) 1 NC_010468.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 3797233 6068311 EcolC_3479 Escherichia coli ATCC 8739 UDP-N-acetylglucosamine acyltransferase YP_001726420.1 3796445 R 481805 CDS YP_001726421.1 170021467 6068317 complement(3797237..3797692) 1 NC_010468.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 3797692 fabZ 6068317 fabZ Escherichia coli ATCC 8739 (3R)-hydroxymyristoyl-ACP dehydratase YP_001726421.1 3797237 R 481805 CDS YP_001726422.1 170021468 6068327 complement(3797797..3798822) 1 NC_010468.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 3798822 lpxD 6068327 lpxD Escherichia coli ATCC 8739 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001726422.1 3797797 R 481805 CDS YP_001726423.1 170021469 6068342 complement(3798826..3799311) 1 NC_010468.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: sdy:SDY_0194 histone-like protein; periplasmic chaperone 3799311 6068342 EcolC_3482 Escherichia coli ATCC 8739 periplasmic chaperone YP_001726423.1 3798826 R 481805 CDS YP_001726424.1 170021470 6068356 complement(3799433..3801865) 1 NC_010468.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 3801865 6068356 EcolC_3483 Escherichia coli ATCC 8739 outer membrane protein assembly factor YaeT YP_001726424.1 3799433 R 481805 CDS YP_001726425.1 170021471 6068364 complement(3801895..3803247) 1 NC_010468.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 3803247 6068364 EcolC_3484 Escherichia coli ATCC 8739 zinc metallopeptidase RseP YP_001726425.1 3801895 R 481805 CDS YP_001726426.1 170021472 6068365 complement(3803259..3804116) 1 NC_010468.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 3804116 cdsA 6068365 cdsA Escherichia coli ATCC 8739 CDP-diglyceride synthase YP_001726426.1 3803259 R 481805 CDS YP_001726427.1 170021473 6068380 complement(3804129..3804890) 1 NC_010468.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 3804890 6068380 EcolC_3486 Escherichia coli ATCC 8739 undecaprenyl pyrophosphate synthase YP_001726427.1 3804129 R 481805 CDS YP_001726428.1 170021474 6068398 complement(3805076..3806272) 1 NC_010468.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3806272 6068398 EcolC_3487 Escherichia coli ATCC 8739 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001726428.1 3805076 R 481805 CDS YP_001726429.1 170021475 6068401 complement(3806364..3806921) 1 NC_010468.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 3806921 frr 6068401 frr Escherichia coli ATCC 8739 ribosome recycling factor YP_001726429.1 3806364 R 481805 CDS YP_001726430.1 170021476 6068406 complement(3807213..3807938) 1 NC_010468.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 3807938 pyrH 6068406 pyrH Escherichia coli ATCC 8739 uridylate kinase YP_001726430.1 3807213 R 481805 CDS YP_001726431.1 170021477 6068416 complement(3808085..3808936) 1 NC_010468.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 3808936 tsf 6068416 tsf Escherichia coli ATCC 8739 elongation factor Ts YP_001726431.1 3808085 R 481805 CDS YP_001726432.1 170021478 6068424 complement(3809194..3809919) 1 NC_010468.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 3809919 rpsB 6068424 rpsB Escherichia coli ATCC 8739 30S ribosomal protein S2 YP_001726432.1 3809194 R 481805 CDS YP_001726433.1 170021479 6068434 3810287..3811081 1 NC_010468.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 3811081 6068434 EcolC_3492 Escherichia coli ATCC 8739 methionine aminopeptidase YP_001726433.1 3810287 D 481805 CDS YP_001726434.1 170021480 6068446 3811143..3813815 1 NC_010468.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 3813815 6068446 EcolC_3493 Escherichia coli ATCC 8739 PII uridylyl-transferase YP_001726434.1 3811143 D 481805 CDS YP_001726435.1 170021481 6068455 3813846..3814670 1 NC_010468.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 3814670 dapD 6068455 dapD Escherichia coli ATCC 8739 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001726435.1 3813846 D 481805 CDS YP_001726436.1 170021482 6068463 3814793..3815536 1 NC_010468.1 PFAM: metallophosphoesterase; KEGG: sbo:SBO_0153 hypothetical protein; phosphodiesterase YaeI 3815536 6068463 EcolC_3495 Escherichia coli ATCC 8739 phosphodiesterase YaeI YP_001726436.1 3814793 D 481805 CDS YP_001726437.1 170021483 6068478 3815698..3816084 1 NC_010468.1 KEGG: sdy:SDY_0181 putative structural protein; hypothetical protein 3816084 6068478 EcolC_3496 Escherichia coli ATCC 8739 hypothetical protein YP_001726437.1 3815698 D 481805 CDS YP_001726438.1 170021484 6068483 complement(3816173..3817330) 1 NC_010468.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 3817330 6068483 EcolC_3497 Escherichia coli ATCC 8739 carbohydrate diacid transcriptional activator CdaR YP_001726438.1 3816173 R 481805 CDS YP_001726439.1 170021485 6068491 complement(3817485..3818909) 1 NC_010468.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 3818909 6068491 EcolC_3498 Escherichia coli ATCC 8739 serine endoprotease YP_001726439.1 3817485 R 481805 CDS YP_001726440.1 170021486 6068497 complement(3819039..3820556) 1 NC_010468.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 3820556 dgt 6068497 dgt Escherichia coli ATCC 8739 deoxyguanosinetriphosphate triphosphohydrolase YP_001726440.1 3819039 R 481805 CDS YP_001726441.1 170021487 6068499 3820640..3821338 1 NC_010468.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 3821338 6068499 EcolC_3500 Escherichia coli ATCC 8739 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001726441.1 3820640 D 481805 CDS YP_001726442.1 170021488 6068502 3821331..3822131 1 NC_010468.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 3822131 6068502 EcolC_3501 Escherichia coli ATCC 8739 vitamin B12-transporter protein BtuF YP_001726442.1 3821331 D 481805 CDS YP_001726443.1 170021489 6068515 3822169..3822792 1 NC_010468.1 PFAM: protein of unknown function UPF0126; KEGG: sbo:SBO_0146 hypothetical protein; hypothetical protein 3822792 6068515 EcolC_3502 Escherichia coli ATCC 8739 hypothetical protein YP_001726443.1 3822169 D 481805 CDS YP_001726444.1 170021490 6068539 complement(3822839..3823183) 1 NC_010468.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 3823183 6068539 EcolC_3503 Escherichia coli ATCC 8739 iron-sulfur cluster insertion protein ErpA YP_001726444.1 3822839 R 481805 CDS YP_001726445.1 170021491 6068554 complement(3823265..3824686) 1 NC_010468.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 3824686 6068554 EcolC_3504 Escherichia coli ATCC 8739 chloride channel protein YP_001726445.1 3823265 R 481805 CDS YP_001726446.1 170021492 6068557 3824911..3826191 1 NC_010468.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 3826191 6068557 EcolC_3505 Escherichia coli ATCC 8739 glutamate-1-semialdehyde aminotransferase YP_001726446.1 3824911 D 481805 CDS YP_001726447.1 170021493 6068583 complement(3826349..3828331) 1 NC_010468.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease 3828331 6068583 EcolC_3506 Escherichia coli ATCC 8739 iron-hydroxamate transporter permease YP_001726447.1 3826349 R 481805 CDS YP_001726448.1 170021494 6068591 complement(3828328..3829218) 1 NC_010468.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 3829218 6068591 EcolC_3507 Escherichia coli ATCC 8739 iron-hydroxamate transporter substrate-binding subunit YP_001726448.1 3828328 R 481805 CDS YP_001726449.1 170021495 6068593 complement(3829218..3830015) 1 NC_010468.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 3830015 6068593 EcolC_3508 Escherichia coli ATCC 8739 iron-hydroxamate transporter ATP-binding subunit YP_001726449.1 3829218 R 481805 CDS YP_001726450.1 170021496 6068606 complement(3830066..3832309) 1 NC_010468.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 3832309 6068606 EcolC_3509 Escherichia coli ATCC 8739 ferrichrome outer membrane transporter YP_001726450.1 3830066 R 481805 CDS YP_001726451.1 170021497 6068634 complement(3832529..3835063) 1 NC_010468.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 3835063 mrcB 6068634 mrcB Escherichia coli ATCC 8739 penicillin-binding protein 1b YP_001726451.1 3832529 R 481805 CDS YP_001726452.1 170021498 6068639 complement(3835259..3837733) 1 NC_010468.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 3837733 6068639 EcolC_3511 Escherichia coli ATCC 8739 ATP-dependent RNA helicase HrpB YP_001726452.1 3835259 R 481805 CDS YP_001726453.1 170021499 6068642 3837762..3838292 1 NC_010468.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: ssn:SSON_0159 hypothetical protein; 2'-5' RNA ligase 3838292 6068642 EcolC_3512 Escherichia coli ATCC 8739 2'-5' RNA ligase YP_001726453.1 3837762 D 481805 CDS YP_001726454.1 170021500 6068652 3838307..3839011 1 NC_010468.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 3839011 6068652 EcolC_3513 Escherichia coli ATCC 8739 sugar fermentation stimulation protein A YP_001726454.1 3838307 D 481805 CDS YP_001726455.1 170021501 6068706 3839189..3839644 1 NC_010468.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: sdy:SDY_0161 DnaK suppressor protein; RNA polymerase-binding transcription factor 3839644 dksA 6068706 dksA Escherichia coli ATCC 8739 RNA polymerase-binding transcription factor YP_001726455.1 3839189 D 481805 CDS YP_001726456.1 170021502 6068710 3839681..3840607 1 NC_010468.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 3840607 6068710 EcolC_3515 Escherichia coli ATCC 8739 glutamyl-Q tRNA(Asp) synthetase YP_001726456.1 3839681 D 481805 CDS YP_001726457.1 170021503 6068735 3840667..3842064 1 NC_010468.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 3842064 pcnB 6068735 pcnB Escherichia coli ATCC 8739 poly(A) polymerase I YP_001726457.1 3840667 D 481805 CDS YP_001726458.1 170021504 6068738 3842061..3842540 1 NC_010468.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 3842540 6068738 EcolC_3517 Escherichia coli ATCC 8739 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001726458.1 3842061 D 481805 CDS YP_001726459.1 170021505 6068741 3842889..3843482 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: stt:t0190 putative fimbrial protein; fimbrial protein 3843482 6068741 EcolC_3518 Escherichia coli ATCC 8739 fimbrial protein YP_001726459.1 3842889 D 481805 CDS YP_001726460.1 170021506 6068743 3843565..3844290 1 NC_010468.1 PFAM: pili assembly chaperone; KEGG: sbo:SBO_0126 probable pilin chaperone; putative chaperone protein EcpD 3844290 6068743 EcolC_3519 Escherichia coli ATCC 8739 putative chaperone protein EcpD YP_001726460.1 3843565 D 481805 CDS YP_001726461.1 170021507 6068747 3844331..3846931 1 NC_010468.1 similar to the fimbrial usher protein PapC; putative outer membrane usher protein 3846931 6068747 EcolC_3520 Escherichia coli ATCC 8739 putative outer membrane usher protein YP_001726461.1 3844331 D 481805 CDS YP_001726462.1 170021508 6064339 3846933..3847502 1 NC_010468.1 KEGG: stt:t0187 putative fimbrial protein; putative fimbrial protein 3847502 6064339 EcolC_3521 Escherichia coli ATCC 8739 putative fimbrial protein YP_001726462.1 3846933 D 481805 CDS YP_001726463.1 170021509 6067422 3847517..3848113 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0146 putative fimbrial protein; fimbrial protein 3848113 6067422 EcolC_3522 Escherichia coli ATCC 8739 fimbrial protein YP_001726463.1 3847517 D 481805 CDS YP_001726464.1 170021510 6067508 3848134..3848724 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0145 putative fimbrial protein; fimbrial protein 3848724 6067508 EcolC_3523 Escherichia coli ATCC 8739 fimbrial protein YP_001726464.1 3848134 D 481805 CDS YP_001726465.1 170021511 6067222 3848736..3849848 1 NC_010468.1 PFAM: Fimbrial protein; KEGG: cko:CKO_03237 hypothetical protein; fimbrial protein 3849848 6067222 EcolC_3524 Escherichia coli ATCC 8739 fimbrial protein YP_001726465.1 3848736 D 481805 CDS YP_001726466.1 170021512 6065475 3849982..3850776 1 NC_010468.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3850776 panB 6065475 panB Escherichia coli ATCC 8739 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001726466.1 3849982 D 481805 CDS YP_001726467.1 170021513 6067499 3850788..3851639 1 NC_010468.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3851639 panC 6067499 panC Escherichia coli ATCC 8739 pantoate--beta-alanine ligase YP_001726467.1 3850788 D 481805 CDS YP_001726468.1 170021514 6065550 complement(3851713..3852615) 1 NC_010468.1 PFAM: putative transposase YhgA family protein; KEGG: sfv:SFV_0122 hypothetical protein; putative transposase YhgA family protein 3852615 6065550 EcolC_3527 Escherichia coli ATCC 8739 putative transposase YhgA family protein YP_001726468.1 3851713 R 481805 CDS YP_001726469.1 170021515 6066021 3852889..3853269 1 NC_010468.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 3853269 6066021 EcolC_3528 Escherichia coli ATCC 8739 aspartate alpha-decarboxylase YP_001726469.1 3852889 D 481805 CDS YP_001726470.1 170021516 6065048 complement(3853273..3854502) 1 NC_010468.1 PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_0138 hypothetical protein; polysaccharide deacetylase 3854502 6065048 EcolC_3529 Escherichia coli ATCC 8739 polysaccharide deacetylase YP_001726470.1 3853273 R 481805 CDS YP_001726471.1 170021517 6067584 complement(3854566..3855006) 1 NC_010468.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sbo:SBO_0118 putative PTS enzyme II B component; PTS system fructose subfamily transporter subunit IIA 3855006 6067584 EcolC_3530 Escherichia coli ATCC 8739 PTS system fructose subfamily transporter subunit IIA YP_001726471.1 3854566 R 481805 CDS YP_001726472.1 170021518 6065005 complement(3855111..3855881) 1 NC_010468.1 PFAM: ABC-2 type transporter; KEGG: sdy:SDY_0037 hypothetical protein; ABC-2 type transporter 3855881 6065005 EcolC_3531 Escherichia coli ATCC 8739 ABC-2 type transporter YP_001726472.1 3855111 R 481805 CDS YP_001726473.1 170021519 6067327 complement(3855878..3856804) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_0135 putative ATP-binding component of a transport system; ABC transporter-like protein 3856804 6067327 EcolC_3532 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001726473.1 3855878 R 481805 CDS YP_001726474.1 170021520 6067504 3856913..3857575 1 NC_010468.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 3857575 6067504 EcolC_3533 Escherichia coli ATCC 8739 carbonic anhydrase YP_001726474.1 3856913 D 481805 CDS YP_001726475.1 170021521 6066064 complement(3857616..3858164) 1 NC_010468.1 KEGG: sdy:SDY_0034 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase 3858164 6066064 EcolC_3534 Escherichia coli ATCC 8739 hypoxanthine phosphoribosyltransferase YP_001726475.1 3857616 R 481805 CDS YP_001726476.1 170021522 6065467 3858358..3860748 1 NC_010468.1 KEGG: sbo:SBO_0113 glucose dehydrogenase; TIGRFAM: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; PFAM: Pyrrolo-quinoline quinone; PQQ-dependent dehydrogenase glucose/quinate/shikimate family protein 3860748 6065467 EcolC_3535 Escherichia coli ATCC 8739 PQQ-dependent dehydrogenase glucose/quinate/shikimate family protein YP_001726476.1 3858358 D 481805 CDS YP_001726477.1 170021523 6065411 complement(3860950..3862500) 1 NC_010468.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 3862500 6065411 EcolC_3536 Escherichia coli ATCC 8739 multicopper oxidase YP_001726477.1 3860950 R 481805 CDS YP_001726478.1 170021524 6065312 3862666..3863013 1 NC_010468.1 KEGG: sdy:SDY_0029 hypothetical protein; hypothetical protein 3863013 6065312 EcolC_3537 Escherichia coli ATCC 8739 hypothetical protein YP_001726478.1 3862666 D 481805 CDS YP_001726479.1 170021525 6064674 3863119..3863985 1 NC_010468.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3863985 6064674 EcolC_3538 Escherichia coli ATCC 8739 spermidine synthase YP_001726479.1 3863119 D 481805 CDS YP_001726480.1 170021526 6066037 3864001..3864795 1 NC_010468.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 3864795 6066037 EcolC_3539 Escherichia coli ATCC 8739 S-adenosylmethionine decarboxylase YP_001726480.1 3864001 D 481805 CDS YP_001726481.1 170021527 6064880 complement(3864832..3865194) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_0026 hypothetical protein; hypothetical protein 3865194 6064880 EcolC_3540 Escherichia coli ATCC 8739 hypothetical protein YP_001726481.1 3864832 R 481805 CDS YP_001726482.1 170021528 6065849 complement(3865369..3867966) 1 NC_010468.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 3867966 6065849 EcolC_3541 Escherichia coli ATCC 8739 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_001726482.1 3865369 R 481805 CDS YP_001726483.1 170021529 6064839 3868321..3870174 1 NC_010468.1 KEGG: sfv:SFV_0108 hypothetical protein; hypothetical protein 3870174 6064839 EcolC_3542 Escherichia coli ATCC 8739 hypothetical protein YP_001726483.1 3868321 D 481805 CDS YP_001726484.1 170021530 6067616 complement(3870245..3871669) 1 NC_010468.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 3871669 6067616 EcolC_3543 Escherichia coli ATCC 8739 dihydrolipoamide dehydrogenase YP_001726484.1 3870245 R 481805 CDS YP_001726485.1 170021531 6064978 complement(3871994..3873886) 1 NC_010468.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 3873886 aceF 6064978 aceF Escherichia coli ATCC 8739 dihydrolipoamide acetyltransferase YP_001726485.1 3871994 R 481805 CDS YP_001726486.1 170021532 6067283 complement(3873901..3876564) 1 NC_010468.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 3876564 aceE 6067283 aceE Escherichia coli ATCC 8739 pyruvate dehydrogenase subunit E1 YP_001726486.1 3873901 R 481805 CDS YP_001726487.1 170021533 6065862 complement(3876725..3877489) 1 NC_010468.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 3877489 pdhR 6065862 pdhR Escherichia coli ATCC 8739 transcriptional regulator PdhR YP_001726487.1 3876725 R 481805 CDS YP_001726488.1 170021534 6064691 3878033..3879403 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sfx:S0111 aromatic amino acid transport protein; aromatic amino acid transporter 3879403 6064691 EcolC_3547 Escherichia coli ATCC 8739 aromatic amino acid transporter YP_001726488.1 3878033 D 481805 CDS YP_001726489.1 170021535 6067352 complement(3879446..3880300) 1 NC_010468.1 involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 3880300 6067352 EcolC_3548 Escherichia coli ATCC 8739 regulatory protein AmpE YP_001726489.1 3879446 R 481805 CDS YP_001726490.1 170021536 6067302 complement(3880297..3880848) 1 NC_010468.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sdy:SDY_0140 regulates AmpC; N-acetyl-anhydromuranmyl-L-alanine amidase 3880848 6067302 EcolC_3549 Escherichia coli ATCC 8739 N-acetyl-anhydromuranmyl-L-alanine amidase YP_001726490.1 3880297 R 481805 CDS YP_001726491.1 170021537 6066722 3880936..3881829 1 NC_010468.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 3881829 6066722 EcolC_3550 Escherichia coli ATCC 8739 quinolinate phosphoribosyltransferase YP_001726491.1 3880936 D 481805 CDS YP_001726492.1 170021538 6067274 3882032..3882472 1 NC_010468.1 KEGG: ssn:SSON_0116 prelipin peptidase dependent protein; putative major pilin subunit 3882472 6067274 EcolC_3551 Escherichia coli ATCC 8739 putative major pilin subunit YP_001726492.1 3882032 D 481805 CDS YP_001726493.1 170021539 6067403 3882482..3883867 1 NC_010468.1 PFAM: type II secretion system protein E; KEGG: sdy:SDY_0137 HofB; hypothetical protein 3883867 6067403 EcolC_3552 Escherichia coli ATCC 8739 hypothetical protein YP_001726493.1 3882482 D 481805 CDS YP_001726494.1 170021540 6066593 3883857..3885059 1 NC_010468.1 PFAM: type II secretion system protein; KEGG: ssn:SSON_0114 putative integral membrane protein; type IV pilin biogenesis protein 3885059 6066593 EcolC_3553 Escherichia coli ATCC 8739 type IV pilin biogenesis protein YP_001726494.1 3883857 D 481805 CDS YP_001726495.1 170021541 6065967 complement(3885094..3886137) 1 NC_010468.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 3886137 6065967 EcolC_3554 Escherichia coli ATCC 8739 guanosine 5'-monophosphate oxidoreductase YP_001726495.1 3885094 R 481805 CDS YP_001726496.1 170021542 6068724 3886362..3886982 1 NC_010468.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3886982 coaE 6068724 coaE Escherichia coli ATCC 8739 dephospho-CoA kinase YP_001726496.1 3886362 D 481805 CDS YP_001726497.1 170021543 6065178 3886982..3887725 1 NC_010468.1 PFAM: protein of unknown function DUF1342; KEGG: ssn:SSON_0110 hypothetical protein; hypothetical protein 3887725 6065178 EcolC_3556 Escherichia coli ATCC 8739 hypothetical protein YP_001726497.1 3886982 D 481805 CDS YP_001726498.1 170021544 6064932 3887735..3887932 1 NC_010468.1 PFAM: protein of unknown function DUF329; KEGG: sdy:SDY_0131 hypothetical protein; zinc-binding protein 3887932 6064932 EcolC_3557 Escherichia coli ATCC 8739 zinc-binding protein YP_001726498.1 3887735 D 481805 CDS YP_001726499.1 170021545 6065146 complement(3888148..3888537) 1 NC_010468.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: ssn:SSON_0107 7,8-dihydro-8-oxoguanine-triphosphatase; nucleoside triphosphate pyrophosphohydrolase 3888537 6065146 EcolC_3558 Escherichia coli ATCC 8739 nucleoside triphosphate pyrophosphohydrolase YP_001726499.1 3888148 R 481805 CDS YP_001726500.1 170021546 6064517 complement(3888597..3891302) 1 NC_010468.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 3891302 6064517 EcolC_3559 Escherichia coli ATCC 8739 preprotein translocase subunit SecA YP_001726500.1 3888597 R 481805 CDS YP_001726501.1 170021547 6067518 complement(3891364..3891876) 1 NC_010468.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 3891876 6067518 EcolC_3560 Escherichia coli ATCC 8739 SecA regulator SecM YP_001726501.1 3891364 R 481805 CDS YP_001726502.1 170021548 6064654 complement(3892107..3893024) 1 NC_010468.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3893024 lpxC 6064654 lpxC Escherichia coli ATCC 8739 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001726502.1 3892107 R 481805 CDS YP_001726503.1 170021549 6066132 complement(3893125..3894276) 1 NC_010468.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 3894276 6066132 EcolC_3562 Escherichia coli ATCC 8739 cell division protein FtsZ YP_001726503.1 3893125 R 481805 CDS YP_001726504.1 170021550 6065608 complement(3894337..3895599) 1 NC_010468.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 3895599 ftsA 6065608 ftsA Escherichia coli ATCC 8739 cell division protein FtsA YP_001726504.1 3894337 R 481805 CDS YP_001726505.1 170021551 6067557 complement(3895596..3896426) 1 NC_010468.1 involved in septum formation; cell division protein FtsQ 3896426 6067557 EcolC_3564 Escherichia coli ATCC 8739 cell division protein FtsQ YP_001726505.1 3895596 R 481805 CDS YP_001726506.1 170021552 6064984 complement(3896428..3897348) 1 NC_010468.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 3897348 ddl 6064984 ddl Escherichia coli ATCC 8739 D-alanine--D-alanine ligase YP_001726506.1 3896428 R 481805 CDS YP_001726507.1 170021553 6064638 complement(3897341..3898816) 1 NC_010468.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 3898816 murC 6064638 murC Escherichia coli ATCC 8739 UDP-N-acetylmuramate--L-alanine ligase YP_001726507.1 3897341 R 481805 CDS YP_001726508.1 170021554 6065888 complement(3898870..3899937) 1 NC_010468.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 3899937 murG 6065888 murG Escherichia coli ATCC 8739 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001726508.1 3898870 R 481805 CDS YP_001726509.1 170021555 6065784 complement(3899934..3901178) 1 NC_010468.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 3901178 6065784 EcolC_3568 Escherichia coli ATCC 8739 cell division protein FtsW YP_001726509.1 3899934 R 481805 CDS YP_001726510.1 170021556 6067407 complement(3901178..3902494) 1 NC_010468.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 3902494 murD 6067407 murD Escherichia coli ATCC 8739 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001726510.1 3901178 R 481805 CDS YP_001726511.1 170021557 6065737 complement(3902497..3903579) 1 NC_010468.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 3903579 mraY 6065737 mraY Escherichia coli ATCC 8739 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001726511.1 3902497 R 481805 CDS YP_001726512.1 170021558 6065724 complement(3903573..3904931) 1 NC_010468.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_0074 D-alanine:D-alanine-adding enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 3904931 murF 6065724 murF Escherichia coli ATCC 8739 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_001726512.1 3903573 R 481805 CDS YP_001726513.1 170021559 6064791 complement(3904928..3906415) 1 NC_010468.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 3906415 murE 6064791 murE Escherichia coli ATCC 8739 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001726513.1 3904928 R 481805 CDS YP_001726514.1 170021560 6066022 complement(3906402..3908168) 1 NC_010468.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: sdy:SDY_0114 penicillin-binding protein 3; peptidoglycan glycosyltransferase 3908168 6066022 EcolC_3573 Escherichia coli ATCC 8739 peptidoglycan glycosyltransferase YP_001726514.1 3906402 R 481805 CDS YP_001726515.1 170021561 6066094 complement(3908184..3908549) 1 NC_010468.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 3908549 6066094 EcolC_3574 Escherichia coli ATCC 8739 cell division protein FtsL YP_001726515.1 3908184 R 481805 CDS YP_001726516.1 170021562 6064428 complement(3908546..3909487) 1 NC_010468.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: sbo:SBO_0070 putative apolipoprotein; S-adenosyl-methyltransferase MraW 3909487 mraW 6064428 mraW Escherichia coli ATCC 8739 S-adenosyl-methyltransferase MraW YP_001726516.1 3908546 R 481805 CDS YP_001726517.1 170021563 6064414 complement(3909489..3909947) 1 NC_010468.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 3909947 6064414 EcolC_3576 Escherichia coli ATCC 8739 cell division protein MraZ YP_001726517.1 3909489 R 481805 CDS YP_001726518.1 170021564 6066561 complement(3910549..3911553) 1 NC_010468.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 3911553 6066561 EcolC_3577 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator FruR YP_001726518.1 3910549 R 481805 CDS YP_001726520.1 170021566 6064722 complement(3911733..3912224) 1 NC_010468.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 3912224 ilvH 6064722 ilvH Escherichia coli ATCC 8739 acetolactate synthase 3 regulatory subunit YP_001726520.1 3911733 R 481805 CDS YP_001726521.1 170021567 6067554 complement(3912227..3913951) 1 NC_010468.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 3913951 6067554 EcolC_3580 Escherichia coli ATCC 8739 acetolactate synthase 3 catalytic subunit YP_001726521.1 3912227 R 481805 CDS YP_001726522.1 170021568 6064870 complement(3914269..3915213) 1 NC_010468.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 3915213 leuO 6064870 leuO Escherichia coli ATCC 8739 leucine transcriptional activator YP_001726522.1 3914269 R 481805 CDS YP_001726523.1 170021569 6067330 3915873..3915959 1 NC_010468.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 3915959 6067330 EcolC_3582 Escherichia coli ATCC 8739 leu operon leader peptide YP_001726523.1 3915873 D 481805 CDS YP_001726524.1 170021570 6065434 3916052..3917623 1 NC_010468.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 3917623 6065434 EcolC_3583 Escherichia coli ATCC 8739 2-isopropylmalate synthase YP_001726524.1 3916052 D 481805 CDS YP_001726525.1 170021571 6064888 3917623..3918714 1 NC_010468.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 3918714 6064888 EcolC_3584 Escherichia coli ATCC 8739 3-isopropylmalate dehydrogenase YP_001726525.1 3917623 D 481805 CDS YP_001726526.1 170021572 6066420 3918717..3920117 1 NC_010468.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 3920117 6066420 EcolC_3585 Escherichia coli ATCC 8739 isopropylmalate isomerase large subunit YP_001726526.1 3918717 D 481805 CDS YP_001726527.1 170021573 6064448 3920128..3920733 1 NC_010468.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 3920733 leuD 6064448 leuD Escherichia coli ATCC 8739 isopropylmalate isomerase small subunit YP_001726527.1 3920128 D 481805 CDS YP_001726528.1 170021574 6066270 complement(3920782..3921960) 1 NC_010468.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0067 putative transport protein; sugar efflux transporter 3921960 6066270 EcolC_3587 Escherichia coli ATCC 8739 sugar efflux transporter YP_001726528.1 3920782 R 481805 CDS YP_001726529.1 170021575 6064871 3922282..3923937 1 NC_010468.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 3923937 6064871 EcolC_3588 Escherichia coli ATCC 8739 transcriptional regulator SgrR YP_001726529.1 3922282 D 481805 CDS YP_001726530.1 170021576 6066442 3924101..3925084 1 NC_010468.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 3925084 tbpA 6066442 tbpA Escherichia coli ATCC 8739 thiamine transporter substrate binding subunit YP_001726530.1 3924101 D 481805 CDS YP_001726531.1 170021577 6067549 3925060..3926670 1 NC_010468.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 3926670 thiP 6067549 thiP Escherichia coli ATCC 8739 thiamine transporter membrane protein YP_001726531.1 3925060 D 481805 CDS YP_001726532.1 170021578 6067171 3926654..3927352 1 NC_010468.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 3927352 thiQ 6067171 thiQ Escherichia coli ATCC 8739 thiamine transporter ATP-binding subunit YP_001726532.1 3926654 D 481805 CDS YP_001726533.1 170021579 6065501 complement(3927466..3928230) 1 NC_010468.1 PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_0052 hypothetical protein; hypothetical protein 3928230 6065501 EcolC_3592 Escherichia coli ATCC 8739 hypothetical protein YP_001726533.1 3927466 R 481805 CDS YP_001726534.1 170021580 6065687 complement(3928316..3929194) 1 NC_010468.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 3929194 6065687 EcolC_3593 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator AraC YP_001726534.1 3928316 R 481805 CDS YP_001726535.1 170021581 6066889 3929533..3931233 1 NC_010468.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 3931233 6066889 EcolC_3594 Escherichia coli ATCC 8739 ribulokinase YP_001726535.1 3929533 D 481805 CDS YP_001726536.1 170021582 6067404 3931244..3932746 1 NC_010468.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 3932746 6067404 EcolC_3595 Escherichia coli ATCC 8739 L-arabinose isomerase YP_001726536.1 3931244 D 481805 CDS YP_001726537.1 170021583 6066010 3933031..3933726 1 NC_010468.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3933726 araD 6066010 araD Escherichia coli ATCC 8739 L-ribulose-5-phosphate 4-epimerase YP_001726537.1 3933031 D 481805 CDS YP_001726538.1 170021584 6067600 3933801..3936152 1 NC_010468.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 3936152 6067600 EcolC_3597 Escherichia coli ATCC 8739 DNA polymerase II YP_001726538.1 3933801 D 481805 CDS YP_001726539.1 170021585 6065943 3936317..3939223 1 NC_010468.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 3939223 6065943 EcolC_3598 Escherichia coli ATCC 8739 ATP-dependent helicase HepA YP_001726539.1 3936317 D 481805 CDS YP_001726540.1 170021586 6065577 3939235..3939894 1 NC_010468.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 3939894 6065577 EcolC_3599 Escherichia coli ATCC 8739 23S rRNA/tRNA pseudouridine synthase A YP_001726540.1 3939235 D 481805 CDS YP_001726541.1 170021587 6065686 complement(3940011..3940826) 1 NC_010468.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 3940826 djlA 6065686 djlA Escherichia coli ATCC 8739 Dna-J like membrane chaperone protein YP_001726541.1 3940011 R 481805 CDS YP_001726542.1 170021588 6065189 3941081..3943435 1 NC_010468.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 3943435 6065189 EcolC_3601 Escherichia coli ATCC 8739 organic solvent tolerance protein YP_001726542.1 3941081 D 481805 CDS YP_001726543.1 170021589 6066759 3943488..3944774 1 NC_010468.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 3944774 6066759 EcolC_3602 Escherichia coli ATCC 8739 peptidyl-prolyl cis-trans isomerase SurA YP_001726543.1 3943488 D 481805 CDS YP_001726544.1 170021590 6065044 3944774..3945763 1 NC_010468.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 3945763 pdxA 6065044 pdxA Escherichia coli ATCC 8739 4-hydroxythreonine-4-phosphate dehydrogenase YP_001726544.1 3944774 D 481805 CDS YP_001726545.1 170021591 6066147 3945760..3946581 1 NC_010468.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 3946581 ksgA 6066147 ksgA Escherichia coli ATCC 8739 dimethyladenosine transferase YP_001726545.1 3945760 D 481805 CDS YP_001726546.1 170021592 6067532 3946584..3946961 1 NC_010468.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 3946961 apaG 6067532 apaG Escherichia coli ATCC 8739 ApaG protein YP_001726546.1 3946584 D 481805 CDS YP_001726547.1 170021593 6064730 3946968..3947810 1 NC_010468.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 3947810 apaH 6064730 apaH Escherichia coli ATCC 8739 diadenosine tetraphosphatase YP_001726547.1 3946968 D 481805 CDS YP_001726548.1 170021594 6065447 complement(3947888..3948367) 1 NC_010468.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 3948367 folA 6065447 folA Escherichia coli ATCC 8739 dihydrofolate reductase YP_001726548.1 3947888 R 481805 CDS YP_001726549.1 170021595 6064728 complement(3948559..3950421) 1 NC_010468.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 3950421 6064728 EcolC_3608 Escherichia coli ATCC 8739 glutathione-regulated potassium-efflux system protein KefC YP_001726549.1 3948559 R 481805 CDS YP_001726550.1 170021596 6067323 complement(3950414..3950944) 1 NC_010468.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 3950944 6067323 EcolC_3609 Escherichia coli ATCC 8739 glutathione-regulated potassium-efflux system ancillary protein KefF YP_001726550.1 3950414 R 481805 CDS YP_001726551.1 170021597 6067519 complement(3951052..3952383) 1 NC_010468.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sfv:SFV_0039 putative transport protein; major facilitator transporter 3952383 6067519 EcolC_3610 Escherichia coli ATCC 8739 major facilitator transporter YP_001726551.1 3951052 R 481805 CDS YP_001726552.1 170021598 6065011 complement(3952440..3952727) 1 NC_010468.1 KEGG: sdy:SDY_0066 putative ferredoxin; putative ferredoxin 3952727 6065011 EcolC_3611 Escherichia coli ATCC 8739 putative ferredoxin YP_001726552.1 3952440 R 481805 CDS YP_001726553.1 170021599 6066013 complement(3952724..3954010) 1 NC_010468.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 3954010 6066013 EcolC_3612 Escherichia coli ATCC 8739 putative oxidoreductase FixC YP_001726553.1 3952724 R 481805 CDS YP_001726554.1 170021600 6066762 complement(3954061..3955002) 1 NC_010468.1 involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 3955002 fixB 6066762 fixB Escherichia coli ATCC 8739 putative electron transfer flavoprotein FixB YP_001726554.1 3954061 R 481805 CDS YP_001726555.1 170021601 6065066 complement(3955017..3955787) 1 NC_010468.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 3955787 6065066 EcolC_3614 Escherichia coli ATCC 8739 putative electron transfer flavoprotein FixA YP_001726555.1 3955017 R 481805 CDS YP_001726556.1 170021602 6065045 3956260..3957774 1 NC_010468.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 3957774 6065045 EcolC_3615 Escherichia coli ATCC 8739 L-carnitine/gamma-butyrobetaine antiporter YP_001726556.1 3956260 D 481805 CDS YP_001726557.1 170021603 6066209 3957805..3958947 1 NC_010468.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 3958947 6066209 EcolC_3616 Escherichia coli ATCC 8739 crotonobetainyl-CoA dehydrogenase YP_001726557.1 3957805 D 481805 CDS YP_001726558.1 170021604 6065959 3959076..3960293 1 NC_010468.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 3960293 6065959 EcolC_3617 Escherichia coli ATCC 8739 crotonobetainyl-CoA:carnitine CoA-transferase YP_001726558.1 3959076 D 481805 CDS YP_001726559.1 170021605 6066113 3960402..3961919 1 NC_010468.1 PFAM: AMP-dependent synthetase and ligase; KEGG: ssn:SSON_0043 probable crotonobetaine/carnitine-CoA ligase; putative crotonobetaine/carnitine-CoA ligase 3961919 caiC 6066113 caiC Escherichia coli ATCC 8739 putative crotonobetaine/carnitine-CoA ligase YP_001726559.1 3960402 D 481805 CDS YP_001726560.1 170021606 6064475 3962028..3962813 1 NC_010468.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 3962813 6064475 EcolC_3619 Escherichia coli ATCC 8739 carnitinyl-CoA dehydratase YP_001726560.1 3962028 D 481805 CDS YP_001726561.1 170021607 6066415 3962819..3963409 1 NC_010468.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 3963409 6066415 EcolC_3620 Escherichia coli ATCC 8739 carnitine operon protein CaiE YP_001726561.1 3962819 D 481805 CDS YP_001726562.1 170021608 6065610 complement(3963528..3963923) 1 NC_010468.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 3963923 6065610 EcolC_3621 Escherichia coli ATCC 8739 DNA-binding transcriptional activator CaiF YP_001726562.1 3963528 R 481805 CDS YP_001726563.1 170021609 6065897 complement(3964185..3967406) 1 NC_010468.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 3967406 carB 6065897 carB Escherichia coli ATCC 8739 carbamoyl phosphate synthase large subunit YP_001726563.1 3964185 R 481805 CDS YP_001726564.1 170021610 6066559 complement(3967424..3968572) 1 NC_010468.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 3968572 6066559 EcolC_3623 Escherichia coli ATCC 8739 carbamoyl phosphate synthase small subunit YP_001726564.1 3967424 R 481805 CDS YP_001726565.1 170021611 6065860 complement(3969028..3969849) 1 NC_010468.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 3969849 6065860 EcolC_3624 Escherichia coli ATCC 8739 dihydrodipicolinate reductase YP_001726565.1 3969028 R 481805 CDS YP_001726566.1 170021612 6067531 complement(3970995..3971945) 1 NC_010468.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3971945 ispH 6067531 ispH Escherichia coli ATCC 8739 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001726566.1 3970995 R 481805 CDS YP_001726567.1 170021613 6066455 complement(3971947..3972396) 1 NC_010468.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: sbo:SBO_0027 probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase; FKBP-type peptidylprolyl isomerase 3972396 6066455 EcolC_3627 Escherichia coli ATCC 8739 FKBP-type peptidylprolyl isomerase YP_001726567.1 3971947 R 481805 CDS YP_001726568.1 170021614 6065960 complement(3972521..3973015) 1 NC_010468.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 3973015 lspA 6065960 lspA Escherichia coli ATCC 8739 lipoprotein signal peptidase YP_001726568.1 3972521 R 481805 CDS YP_001726569.1 170021615 6066553 complement(3973015..3975831) 1 NC_010468.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 3975831 ileS 6066553 ileS Escherichia coli ATCC 8739 isoleucyl-tRNA synthetase YP_001726569.1 3973015 R 481805 CDS YP_001726570.1 170021616 6067138 complement(3975874..3976815) 1 NC_010468.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 3976815 6067138 EcolC_3630 Escherichia coli ATCC 8739 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001726570.1 3975874 R 481805 CDS YP_001726571.1 170021617 6065941 3977144..3977407 1 NC_010468.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 3977407 rpsT 6065941 rpsT Escherichia coli ATCC 8739 30S ribosomal protein S20 YP_001726571.1 3977144 D 481805 CDS YP_001726572.1 170021618 6066453 join(3977883..3978137,3978137..3978580) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 3978580 6066453 EcolC_3632 Escherichia coli ATCC 8739 insertion element protein YP_001726572.1 3977883 D 481805 CDS YP_001726573.1 170021619 6067165 3981677..3981925 1 NC_010468.1 hypothetical protein 3981925 6067165 EcolC_3635 Escherichia coli ATCC 8739 hypothetical protein YP_001726573.1 3981677 D 481805 CDS YP_001726574.1 170021620 6067492 3982020..3982643 1 NC_010468.1 KEGG: ssn:SSON_0023 hypothetical protein; hypothetical protein 3982643 6067492 EcolC_3636 Escherichia coli ATCC 8739 hypothetical protein YP_001726574.1 3982020 D 481805 CDS YP_001726575.1 170021621 6065391 complement(3982681..3983586) 1 NC_010468.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 3983586 nhaR 6065391 nhaR Escherichia coli ATCC 8739 transcriptional activator NhaR YP_001726575.1 3982681 R 481805 CDS YP_001726576.1 170021622 6066352 complement(3983646..3984812) 1 NC_010468.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 3984812 nhaA 6066352 nhaA Escherichia coli ATCC 8739 pH-dependent sodium/proton antiporter YP_001726576.1 3983646 R 481805 CDS YP_001726577.1 170021623 6065040 3985398..3985550 1 NC_010468.1 PFAM: Hok/gef cell toxic protein; KEGG: sbo:SBO_0017 Gef; Hok/gef cell toxic protein 3985550 6065040 EcolC_3639 Escherichia coli ATCC 8739 Hok/gef cell toxic protein YP_001726577.1 3985398 D 481805 CDS YP_001726578.1 170021624 6064669 3985628..3986740 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein 3986740 6064669 EcolC_3640 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001726578.1 3985628 D 481805 CDS YP_001726579.1 170021625 6065813 complement(3987003..3988133) 1 NC_010468.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 3988133 6065813 EcolC_3641 Escherichia coli ATCC 8739 chaperone protein DnaJ YP_001726579.1 3987003 R 481805 CDS YP_001726580.1 170021626 6064767 complement(3988222..3990138) 1 NC_010468.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 3990138 dnaK 6064767 dnaK Escherichia coli ATCC 8739 molecular chaperone DnaK YP_001726580.1 3988222 R 481805 CDS YP_001726581.1 170021627 6065787 3990515..3990919 1 NC_010468.1 KEGG: ssn:SSON_0013 hypothetical protein; hypothetical protein 3990919 6065787 EcolC_3643 Escherichia coli ATCC 8739 hypothetical protein YP_001726581.1 3990515 D 481805 CDS YP_001726582.1 170021628 6065219 3990945..3991658 1 NC_010468.1 PFAM: protein of unknown function UPF0174; KEGG: ssn:SSON_0012 putative oxidoreductase; hypothetical protein 3991658 6065219 EcolC_3644 Escherichia coli ATCC 8739 hypothetical protein YP_001726582.1 3990945 D 481805 CDS YP_001726583.1 170021629 6065785 3991807..3992373 1 NC_010468.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: ssn:SSON_0011 hypothetical protein; hypothetical protein 3992373 6065785 EcolC_3645 Escherichia coli ATCC 8739 hypothetical protein YP_001726583.1 3991807 D 481805 CDS YP_001726584.1 170021630 6067032 complement(3992408..3992995) 1 NC_010468.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 3992995 mogA 6067032 mogA Escherichia coli ATCC 8739 molybdenum cofactor biosynthesis protein MogA YP_001726584.1 3992408 R 481805 CDS YP_001726585.1 170021631 6066215 complement(3993110..3994063) 1 NC_010468.1 KEGG: sbo:SBO_0009 transaldolase B; TIGRFAM: transaldolase; PFAM: Transaldolase; transaldolase B 3994063 6066215 EcolC_3647 Escherichia coli ATCC 8739 transaldolase B YP_001726585.1 3993110 R 481805 CDS YP_001726586.1 170021632 6065647 3994342..3995772 1 NC_010468.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdy:SDY_0007 inner membrane transport protein; amino acid carrier protein 3995772 6065647 EcolC_3648 Escherichia coli ATCC 8739 amino acid carrier protein YP_001726586.1 3994342 D 481805 CDS YP_001726587.1 170021633 6065175 3995842..3996618 1 NC_010468.1 PFAM: protein of unknown function DUF328; KEGG: sdy:SDY_0006 hypothetical protein; hypothetical protein 3996618 6065175 EcolC_3649 Escherichia coli ATCC 8739 hypothetical protein YP_001726587.1 3995842 D 481805 CDS YP_001726588.1 170021634 6066297 complement(3996771..3997067) 1 NC_010468.1 KEGG: ssn:SSON_0005 hypothetical protein; hypothetical protein 3997067 6066297 EcolC_3650 Escherichia coli ATCC 8739 hypothetical protein YP_001726588.1 3996771 R 481805 CDS YP_001726589.1 170021635 6065834 complement(3997281..3998567) 1 NC_010468.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3998567 6065834 EcolC_3651 Escherichia coli ATCC 8739 threonine synthase YP_001726589.1 3997281 R 481805 CDS YP_001726590.1 170021636 6066546 complement(3998568..3999500) 1 NC_010468.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3999500 6066546 EcolC_3652 Escherichia coli ATCC 8739 homoserine kinase YP_001726590.1 3998568 R 481805 CDS YP_001726591.1 170021637 6065835 complement(3999502..4001964) 1 NC_010468.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 4001964 thrA 6065835 thrA Escherichia coli ATCC 8739 bifunctional aspartokinase I/homoserine dehydrogenase I YP_001726591.1 3999502 R 481805 CDS YP_001726592.1 170021638 6065833 complement(4002324..4003010) 1 NC_010468.1 member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 4003010 6065833 EcolC_3654 Escherichia coli ATCC 8739 putative RNA methyltransferase YP_001726592.1 4002324 R 481805 CDS YP_001726593.1 170021639 6065456 4003646..4004362 1 NC_010468.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sdy:SDY_4662 negative response regulator of genes in aerobic pathways; two-component response regulator 4004362 6065456 EcolC_3655 Escherichia coli ATCC 8739 two-component response regulator YP_001726593.1 4003646 D 481805 CDS YP_001726594.1 170021640 6065911 complement(4004420..4005772) 1 NC_010468.1 PFAM: Inner membrane CreD family protein; KEGG: sfx:S4703 inner membrane protein CreD; hypothetical protein 4005772 6065911 EcolC_3656 Escherichia coli ATCC 8739 hypothetical protein YP_001726594.1 4004420 R 481805 CDS YP_001726595.1 170021641 6066129 complement(4005830..4007254) 1 NC_010468.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4007254 6066129 EcolC_3657 Escherichia coli ATCC 8739 sensory histidine kinase CreC YP_001726595.1 4005830 R 481805 CDS YP_001726596.1 170021642 6065801 complement(4007254..4007943) 1 NC_010468.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4007943 6065801 EcolC_3658 Escherichia coli ATCC 8739 DNA-binding response regulator CreB YP_001726596.1 4007254 R 481805 CDS YP_001726597.1 170021643 6065143 complement(4007956..4008429) 1 NC_010468.1 PFAM: CreA family protein; KEGG: sdy:SDY_4658 hypothetical protein; hypothetical protein 4008429 6065143 EcolC_3659 Escherichia coli ATCC 8739 hypothetical protein YP_001726597.1 4007956 R 481805 CDS YP_001726598.1 170021644 6065311 4008640..4009509 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: sbo:SBO_4459 right origin-binding protein; AraC family transcriptional regulator 4009509 6065311 EcolC_3660 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726598.1 4008640 D 481805 CDS YP_001726599.1 170021645 6064808 complement(4009506..4010153) 1 NC_010468.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4010153 6064808 EcolC_3661 Escherichia coli ATCC 8739 phosphoglycerate mutase YP_001726599.1 4009506 R 481805 CDS YP_001726600.1 170021646 6066705 4010205..4010726 1 NC_010468.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4010726 6066705 EcolC_3662 Escherichia coli ATCC 8739 NTPase YP_001726600.1 4010205 D 481805 CDS YP_001726601.1 170021647 6066703 complement(4010811..4011137) 1 NC_010468.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4011137 6066703 EcolC_3663 Escherichia coli ATCC 8739 Trp operon repressor YP_001726601.1 4010811 R 481805 CDS YP_001726602.1 170021648 6067270 complement(4011227..4013164) 1 NC_010468.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4013164 6067270 EcolC_3664 Escherichia coli ATCC 8739 lytic murein transglycosylase YP_001726602.1 4011227 R 481805 CDS YP_001726603.1 170021649 6065370 4013375..4015042 1 NC_010468.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 4015042 6065370 EcolC_3665 Escherichia coli ATCC 8739 putative ABC transporter ATP-binding protein YP_001726603.1 4013375 D 481805 CDS YP_001726604.1 170021650 6065436 complement(4015349..4016581) 1 NC_010468.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4016581 6065436 EcolC_3666 Escherichia coli ATCC 8739 nicotinamide-nucleotide adenylyltransferase YP_001726604.1 4015349 R 481805 CDS YP_001726605.1 170021651 6066137 complement(4016602..4017984) 1 NC_010468.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4017984 6066137 EcolC_3667 Escherichia coli ATCC 8739 DNA repair protein RadA YP_001726605.1 4016602 R 481805 CDS YP_001726606.1 170021652 6067415 complement(4018033..4019001) 1 NC_010468.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4019001 serB 6067415 serB Escherichia coli ATCC 8739 phosphoserine phosphatase YP_001726606.1 4018033 R 481805 CDS YP_001726607.1 170021653 6065271 4019107..4019751 1 NC_010468.1 KEGG: sbo:SBO_4450 hypothetical protein; hypothetical protein 4019751 6065271 EcolC_3669 Escherichia coli ATCC 8739 hypothetical protein YP_001726607.1 4019107 D 481805 CDS YP_001726608.1 170021654 6065956 4019779..4020795 1 NC_010468.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4020795 lplA 6065956 lplA Escherichia coli ATCC 8739 lipoate-protein ligase A YP_001726608.1 4019779 D 481805 CDS YP_001726609.1 170021655 6066581 4020827..4021090 1 NC_010468.1 PFAM: helix-turn-helix domain protein; KEGG: sfv:SFV_4419 hypothetical protein; helix-turn-helix domain-containing protein 4021090 6066581 EcolC_3671 Escherichia coli ATCC 8739 helix-turn-helix domain-containing protein YP_001726609.1 4020827 D 481805 CDS YP_001726610.1 170021656 6065926 complement(4021250..4021969) 1 NC_010468.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4021969 deoD 6065926 deoD Escherichia coli ATCC 8739 purine nucleoside phosphorylase YP_001726610.1 4021250 R 481805 CDS YP_001726611.1 170021657 6066784 complement(4022049..4023272) 1 NC_010468.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4023272 6066784 EcolC_3673 Escherichia coli ATCC 8739 phosphopentomutase YP_001726611.1 4022049 R 481805 CDS YP_001726612.1 170021658 6066547 complement(4023324..4024646) 1 NC_010468.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4024646 deoA 6066547 deoA Escherichia coli ATCC 8739 thymidine phosphorylase YP_001726612.1 4023324 R 481805 CDS YP_001726613.1 170021659 6066195 complement(4024773..4025552) 1 NC_010468.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4025552 6066195 EcolC_3675 Escherichia coli ATCC 8739 deoxyribose-phosphate aldolase YP_001726613.1 4024773 R 481805 CDS YP_001726614.1 170021660 6065963 4025810..4027360 1 NC_010468.1 KEGG: ssn:SSON_4531 hypothetical protein; hypothetical protein 4027360 6065963 EcolC_3676 Escherichia coli ATCC 8739 hypothetical protein YP_001726614.1 4025810 D 481805 CDS YP_001726615.1 170021661 6065870 4027332..4028195 1 NC_010468.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: sfv:SFV_4413 putative activating enzyme; radical SAM domain-containing protein 4028195 6065870 EcolC_3677 Escherichia coli ATCC 8739 radical SAM domain-containing protein YP_001726615.1 4027332 D 481805 CDS YP_001726616.1 170021662 6065675 complement(4028712..4029494) 1 NC_010468.1 PFAM: TatD-related deoxyribonuclease; KEGG: ssn:SSON_4529 Mg-dependent DNase; putative deoxyribonuclease YjjV 4029494 6065675 EcolC_3678 Escherichia coli ATCC 8739 putative deoxyribonuclease YjjV YP_001726616.1 4028712 R 481805 CDS YP_001726617.1 170021663 6066257 complement(4029491..4030564) 1 NC_010468.1 PFAM: Patatin; KEGG: ssn:SSON_4528 hypothetical protein; patatin 4030564 6066257 EcolC_3679 Escherichia coli ATCC 8739 patatin YP_001726617.1 4029491 R 481805 CDS YP_001726618.1 170021664 6065503 complement(4030686..4030847) 1 NC_010468.1 PFAM: protein of unknown function DUF1328; KEGG: ssn:SSON_4527 hypothetical protein; hypothetical protein 4030847 6065503 EcolC_3680 Escherichia coli ATCC 8739 hypothetical protein YP_001726618.1 4030686 R 481805 CDS YP_001726619.1 170021665 6064655 complement(4030974..4031579) 1 NC_010468.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ssn:SSON_4526 hyperosmotically inducible periplasmic protein; hypothetical protein 4031579 6064655 EcolC_3681 Escherichia coli ATCC 8739 hypothetical protein YP_001726619.1 4030974 R 481805 CDS YP_001726620.1 170021666 6067181 complement(4031972..4033561) 1 NC_010468.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4033561 prfC 6067181 prfC Escherichia coli ATCC 8739 peptide chain release factor 3 YP_001726620.1 4031972 R 481805 CDS YP_001726621.1 170021667 6066735 complement(4033652..4034329) 1 NC_010468.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4034329 6066735 EcolC_3683 Escherichia coli ATCC 8739 nucleotidase YP_001726621.1 4033652 R 481805 CDS YP_001726622.1 170021668 6065857 complement(4034344..4034790) 1 NC_010468.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4034790 rimI 6065857 rimI Escherichia coli ATCC 8739 ribosomal-protein-alanine N-acetyltransferase YP_001726622.1 4034344 R 481805 CDS YP_001726623.1 170021669 6066294 complement(4034759..4035172) 1 NC_010468.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4035172 6066294 EcolC_3685 Escherichia coli ATCC 8739 DNA polymerase III subunit psi YP_001726623.1 4034759 R 481805 CDS YP_001726624.1 170021670 6067053 4035275..4036306 1 NC_010468.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4036306 rsmC 6067053 rsmC Escherichia coli ATCC 8739 16S ribosomal RNA m2G1207 methyltransferase YP_001726624.1 4035275 D 481805 CDS YP_001726625.1 170021671 6065530 complement(4036976..4037212) 1 NC_010468.1 PFAM: protein of unknown function DUF1435; KEGG: sbo:SBO_4428 putative inner membrane protein; hypothetical protein 4037212 6065530 EcolC_3687 Escherichia coli ATCC 8739 hypothetical protein YP_001726625.1 4036976 R 481805 CDS YP_001726626.1 170021672 6065962 4037353..4038141 1 NC_010468.1 PFAM: ferric iron reductase; KEGG: sbo:SBO_4427 hypothetical protein; ferric hydroximate transport ferric iron reductase 4038141 6065962 EcolC_3688 Escherichia coli ATCC 8739 ferric hydroximate transport ferric iron reductase YP_001726626.1 4037353 D 481805 CDS YP_001726627.1 170021673 6067507 complement(4038179..4038802) 1 NC_010468.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4038802 6067507 EcolC_3689 Escherichia coli ATCC 8739 DNA-binding transcriptional activator BglJ YP_001726627.1 4038179 R 481805 CDS YP_001726628.1 170021674 6064438 complement(4038814..4039539) 1 NC_010468.1 PFAM: regulatory protein LuxR; KEGG: sbo:SBO_4425 putative regulator; LuxR family transcriptional regulator 4039539 6064438 EcolC_3690 Escherichia coli ATCC 8739 LuxR family transcriptional regulator YP_001726628.1 4038814 R 481805 CDS YP_001726629.1 170021675 6066279 4040158..4040928 1 NC_010468.1 PFAM: protein of unknown function DUF1212; KEGG: sfv:SFV_4395 putative structural protein; hypothetical protein 4040928 6066279 EcolC_3691 Escherichia coli ATCC 8739 hypothetical protein YP_001726629.1 4040158 D 481805 CDS YP_001726630.1 170021676 6067609 4040919..4041392 1 NC_010468.1 KEGG: sfv:SFV_4394 hypothetical protein; hypothetical protein 4041392 6067609 EcolC_3692 Escherichia coli ATCC 8739 hypothetical protein YP_001726630.1 4040919 D 481805 CDS YP_001726631.1 170021677 6067685 4041500..4042039 1 NC_010468.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4042039 6067685 EcolC_3693 Escherichia coli ATCC 8739 primosomal protein DnaI YP_001726631.1 4041500 D 481805 CDS YP_001726632.1 170021678 6067610 4042042..4042779 1 NC_010468.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4042779 6067610 EcolC_3694 Escherichia coli ATCC 8739 DNA replication protein DnaC YP_001726632.1 4042042 D 481805 CDS YP_001726633.1 170021679 6065616 4042825..4043322 1 NC_010468.1 KEGG: ssn:SSON_4506 putative glycoprotein/receptor; hypothetical protein 4043322 6065616 EcolC_3695 Escherichia coli ATCC 8739 hypothetical protein YP_001726633.1 4042825 D 481805 CDS YP_001726634.1 170021680 6066737 4043576..4045867 1 NC_010468.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4045867 6066737 EcolC_3696 Escherichia coli ATCC 8739 phosphoglycerol transferase I YP_001726634.1 4043576 D 481805 CDS YP_001726635.1 170021681 6065936 complement(4046007..4047029) 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_4504 putative oxidoreductase; alcohol dehydrogenase 4047029 6065936 EcolC_3697 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001726635.1 4046007 R 481805 CDS YP_001726636.1 170021682 6065151 4047168..4048082 1 NC_010468.1 PFAM: GntR domain protein; KEGG: eca:ECA4381 putative DNA-binding protein; GntR family transcriptional regulator 4048082 6065151 EcolC_3698 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001726636.1 4047168 D 481805 CDS YP_001726637.1 170021683 6068690 4048299..4049660 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_4387 putative transport protein; major facilitator transporter 4049660 6068690 EcolC_3699 Escherichia coli ATCC 8739 major facilitator transporter YP_001726637.1 4048299 D 481805 CDS YP_001726638.1 170021684 6067269 complement(4049709..4051373) 1 NC_010468.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sfv:SFV_4386 methyl-accepting chemotaxis protein I; methyl-accepting chemotaxis sensory transducer 4051373 6067269 EcolC_3700 Escherichia coli ATCC 8739 methyl-accepting chemotaxis sensory transducer YP_001726638.1 4049709 R 481805 CDS YP_001726639.1 170021685 6064763 complement(4051492..4051938) 1 NC_010468.1 TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein MarR; KEGG: sfv:SFV_4385 homoprotocatechuate degradative operon repressor; MarR family transcriptional regulator 4051938 6064763 EcolC_3701 Escherichia coli ATCC 8739 MarR family transcriptional regulator YP_001726639.1 4051492 R 481805 CDS YP_001726640.1 170021686 6066149 4052210..4053499 1 NC_010468.1 KEGG: sbo:SBO_4412 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomerase; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase subunit HpaG1 4053499 6066149 EcolC_3702 Escherichia coli ATCC 8739 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase subunit HpaG1 YP_001726640.1 4052210 D 481805 CDS YP_001726641.1 170021687 6065126 4053496..4054962 1 NC_010468.1 TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: sbo:SBO_4411 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 4054962 6065126 EcolC_3703 Escherichia coli ATCC 8739 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_001726641.1 4053496 D 481805 CDS YP_001726642.1 170021688 6065740 4054964..4055815 1 NC_010468.1 KEGG: sbo:SBO_4410 homoprotocatechuate dyoxygenase; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; 3,4-dihydroxyphenylacetate 2,3-dioxygenase 4055815 6065740 EcolC_3704 Escherichia coli ATCC 8739 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_001726642.1 4054964 D 481805 CDS YP_001726643.1 170021689 6064640 4055825..4056205 1 NC_010468.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: sfx:S4651 5-carboxymethyl-2-hydroxymuconate delta-isomerase; 5-carboxymethyl-2-hydroxymuconate isomerase 4056205 6064640 EcolC_3705 Escherichia coli ATCC 8739 5-carboxymethyl-2-hydroxymuconate isomerase YP_001726643.1 4055825 D 481805 CDS YP_001726644.1 170021690 6065597 4056273..4057076 1 NC_010468.1 KEGG: ssn:SSON_4495 2-oxo-hept-3-ene-1,7-dioate hydratase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 4057076 6065597 EcolC_3706 Escherichia coli ATCC 8739 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_001726644.1 4056273 D 481805 CDS YP_001726645.1 170021691 6065863 4057087..4057875 1 NC_010468.1 KEGG: sbo:SBO_4407 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 4057875 6065863 EcolC_3707 Escherichia coli ATCC 8739 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_001726645.1 4057087 D 481805 CDS YP_001726646.1 170021692 6064898 4058050..4059426 1 NC_010468.1 TIGRFAM: 4-hydroxyphenylacetate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4406 putative 4-hydroxyphenylacetate permease; 4-hydroxyphenylacetate transporter 4059426 6064898 EcolC_3708 Escherichia coli ATCC 8739 4-hydroxyphenylacetate transporter YP_001726646.1 4058050 D 481805 CDS YP_001726647.1 170021693 6064706 4059436..4060326 1 NC_010468.1 TIGRFAM: 4-hydroxyphenylacetate catabolism regulatory protein HpaA; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; KEGG: kpn:KPN_04781 4-hydroxyphenylacetate catabolism; AraC family transcriptional regulator 4060326 6064706 EcolC_3709 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726647.1 4059436 D 481805 CDS YP_001726648.1 170021694 6064673 4060577..4062139 1 NC_010468.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: ssn:SSON_4489 4-hydroxyphenylacetate 3-monooxygenase; 4-hydroxyphenylacetate 3-monooxygenase oxygenase subunit 4062139 6064673 EcolC_3710 Escherichia coli ATCC 8739 4-hydroxyphenylacetate 3-monooxygenase oxygenase subunit YP_001726648.1 4060577 D 481805 CDS YP_001726649.1 170021695 6064670 4062157..4062669 1 NC_010468.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit; PFAM: flavin reductase domain protein FMN-binding; KEGG: sbo:SBO_4403 4-hydroxyphenylacetate 3-monooxygenase coupling protein; 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit 4062669 6064670 EcolC_3711 Escherichia coli ATCC 8739 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit YP_001726649.1 4062157 D 481805 CDS YP_001726650.1 170021696 6067176 4063062..4065212 1 NC_010468.1 PFAM: carbon starvation protein CstA; KEGG: sdy:SDY_4607 putative carbon starvation protein; carbon starvation protein CstA 4065212 6067176 EcolC_3712 Escherichia coli ATCC 8739 carbon starvation protein CstA YP_001726650.1 4063062 D 481805 CDS YP_001726651.1 170021697 6067182 4065343..4065546 1 NC_010468.1 PFAM: protein of unknown function DUF466; KEGG: sdy:SDY_4606 hypothetical protein; hypothetical protein 4065546 6067182 EcolC_3713 Escherichia coli ATCC 8739 hypothetical protein YP_001726651.1 4065343 D 481805 CDS YP_001726652.1 170021698 6067166 4065557..4066513 1 NC_010468.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sfv:SFV_4371 hypothetical protein; putative GTP-binding protein YjiA 4066513 6067166 EcolC_3714 Escherichia coli ATCC 8739 putative GTP-binding protein YjiA YP_001726652.1 4065557 D 481805 CDS YP_001726653.1 170021699 6066758 complement(4066582..4068234) 1 NC_010468.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: gka:GK3294 hypothetical protein; hypothetical protein 4068234 6066758 EcolC_3715 Escherichia coli ATCC 8739 hypothetical protein YP_001726653.1 4066582 R 481805 CDS YP_001726654.1 170021700 6066440 complement(4068457..4069323) 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 4069323 6066440 EcolC_3716 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001726654.1 4068457 R 481805 CDS YP_001726655.1 170021701 6068654 complement(4069320..4069619) 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 4069619 6068654 EcolC_3717 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001726655.1 4069320 R 481805 CDS YP_001726656.1 170021702 6068714 4070347..4072104 1 NC_010468.1 PFAM: restriction modification system DNA specificity domain; KEGG: sfx:S4635 hypothetical protein; restriction modification system DNA specificity subunit 4072104 6068714 EcolC_3719 Escherichia coli ATCC 8739 restriction modification system DNA specificity subunit YP_001726656.1 4070347 D 481805 CDS YP_001726657.1 170021703 6068718 4072325..4072666 1 NC_010468.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 4072666 6068718 EcolC_3720 Escherichia coli ATCC 8739 endoribonuclease SymE YP_001726657.1 4072325 D 481805 CDS YP_001726658.1 170021704 6065928 complement(4072713..4074806) 1 NC_010468.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: pcr:Pcryo_1606 protein of unknown function DUF1524 RloF; hypothetical protein 4074806 6065928 EcolC_3721 Escherichia coli ATCC 8739 hypothetical protein YP_001726658.1 4072713 R 481805 CDS YP_001726659.1 170021705 6068559 complement(4074903..4075067) 1 NC_010468.1 PFAM: protein of unknown function DUF1127; KEGG: sdy:SDY_4602 hypothetical protein; hypothetical protein 4075067 6068559 EcolC_3722 Escherichia coli ATCC 8739 hypothetical protein YP_001726659.1 4074903 R 481805 CDS YP_001726660.1 170021706 6068694 4075244..4076656 1 NC_010468.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sdy:SDY_4601 putative regulator; transcriptional regulator 4076656 6068694 EcolC_3723 Escherichia coli ATCC 8739 transcriptional regulator YP_001726660.1 4075244 D 481805 CDS YP_001726661.1 170021707 6068647 complement(4076898..4077842) 1 NC_010468.1 PFAM: putative transposase YhgA family protein; KEGG: sdy:SDY_4600 hypothetical protein; putative transposase YhgA family protein 4077842 6068647 EcolC_3724 Escherichia coli ATCC 8739 putative transposase YhgA family protein YP_001726661.1 4076898 R 481805 CDS YP_001726662.1 170021708 6064413 4078309..4079535 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4389 putative transport protein; major facilitator transporter 4079535 6064413 EcolC_3725 Escherichia coli ATCC 8739 major facilitator transporter YP_001726662.1 4078309 D 481805 CDS YP_001726663.1 170021709 6066048 4079568..4080860 1 NC_010468.1 PFAM: protein of unknown function DUF445; KEGG: sbo:SBO_4388 hypothetical protein; hypothetical protein 4080860 6066048 EcolC_3726 Escherichia coli ATCC 8739 hypothetical protein YP_001726663.1 4079568 D 481805 CDS YP_001726664.1 170021710 6064440 4080870..4081109 1 NC_010468.1 KEGG: kpn:KPN_04766 hypothetical protein; hypothetical protein 4081109 6064440 EcolC_3727 Escherichia coli ATCC 8739 hypothetical protein YP_001726664.1 4080870 D 481805 CDS YP_001726665.1 170021711 6065654 4081205..4082356 1 NC_010468.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: cko:CKO_03458 hypothetical protein; 2-hydroxyglutaryl-CoA dehydratase subunit D 4082356 6065654 EcolC_3728 Escherichia coli ATCC 8739 2-hydroxyglutaryl-CoA dehydratase subunit D YP_001726665.1 4081205 D 481805 CDS YP_001726666.1 170021712 6064340 4082366..4083133 1 NC_010468.1 TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: sdy:SDY_4596 putative enzyme; CoA-substrate-specific enzyme activase 4083133 6064340 EcolC_3729 Escherichia coli ATCC 8739 CoA-substrate-specific enzyme activase YP_001726666.1 4082366 D 481805 CDS YP_001726667.1 170021713 6064359 4083130..4083387 1 NC_010468.1 KEGG: sbo:SBO_4385 hypothetical protein; hypothetical protein 4083387 6064359 EcolC_3730 Escherichia coli ATCC 8739 hypothetical protein YP_001726667.1 4083130 D 481805 CDS YP_001726668.1 170021714 6064456 4083452..4084312 1 NC_010468.1 PFAM: SdiA-regulated domain protein; KEGG: sbo:SBO_4384 hypothetical protein; SdiA-regulated domain-containing protein 4084312 6064456 EcolC_3731 Escherichia coli ATCC 8739 SdiA-regulated domain-containing protein YP_001726668.1 4083452 D 481805 CDS YP_001726669.1 170021715 6064590 4084380..4085558 1 NC_010468.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: sbo:SBO_4383 putative transport protein; hypothetical protein 4085558 6064590 EcolC_3732 Escherichia coli ATCC 8739 hypothetical protein YP_001726669.1 4084380 D 481805 CDS YP_001726670.1 170021716 6064361 4086374..4087057 1 NC_010468.1 PFAM: nucleoside recognition domain protein; KEGG: sfx:S4444 hypothetical protein; nucleoside recognition domain-containing protein 4087057 6064361 EcolC_3734 Escherichia coli ATCC 8739 nucleoside recognition domain-containing protein YP_001726670.1 4086374 D 481805 CDS YP_001726671.1 170021717 6064396 4087054..4087515 1 NC_010468.1 PFAM: nucleoside recognition domain protein; KEGG: sbo:SBO_4380 hypothetical protein; hypothetical protein 4087515 6064396 EcolC_3735 Escherichia coli ATCC 8739 hypothetical protein YP_001726671.1 4087054 D 481805 CDS YP_001726672.1 170021718 6064657 4087528..4088700 1 NC_010468.1 KEGG: sbo:SBO_4379 isoaspartyl dipeptidase; TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; Amidohydrolase 3; isoaspartyl dipeptidase 4088700 6064657 EcolC_3736 Escherichia coli ATCC 8739 isoaspartyl dipeptidase YP_001726672.1 4087528 D 481805 CDS YP_001726673.1 170021719 6067725 4088765..4089676 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_4199 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 4089676 6067725 EcolC_3737 Escherichia coli ATCC 8739 putative DNA-binding transcriptional regulator YP_001726673.1 4088765 D 481805 CDS YP_001726674.1 170021720 6068692 complement(4089669..4090061) 1 NC_010468.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4090061 iraD 6068692 iraD Escherichia coli ATCC 8739 DNA replication/recombination/repair protein YP_001726674.1 4089669 R 481805 CDS YP_001726675.1 170021721 6068701 4090733..4091563 1 NC_010468.1 KEGG: ssn:SSON_4480 hypothetical protein; hypothetical protein 4091563 6068701 EcolC_3739 Escherichia coli ATCC 8739 hypothetical protein YP_001726675.1 4090733 D 481805 CDS YP_001726676.1 170021722 6068618 complement(4091704..4092477) 1 NC_010468.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4092477 6068618 EcolC_3740 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor UxuR YP_001726676.1 4091704 R 481805 CDS YP_001726677.1 170021723 6068459 complement(4092692..4093483) 1 NC_010468.1 PFAM: Mannitol dehydrogenase domain; KEGG: ssn:SSON_4478 D-mannonate oxidoreductase; mannitol dehydrogenase domain-containing protein 4093483 6068459 EcolC_3741 Escherichia coli ATCC 8739 mannitol dehydrogenase domain-containing protein YP_001726677.1 4092692 R 481805 CDS YP_001726678.1 170021724 6068116 complement(4093533..4094702) 1 NC_010468.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4094702 6068116 EcolC_3742 Escherichia coli ATCC 8739 mannonate dehydratase YP_001726678.1 4093533 R 481805 CDS YP_001726679.1 170021725 6067380 complement(4095489..4096391) 1 NC_010468.1 PFAM: Fimbrial protein ; FimH mannose-binding domain protein; KEGG: sfv:SFV_4206 FimH protein precursor; FimH mannose-binding domain-containing protein 4096391 6067380 EcolC_3743 Escherichia coli ATCC 8739 FimH mannose-binding domain-containing protein YP_001726679.1 4095489 R 481805 CDS YP_001726680.1 170021726 6068020 4096944..4097243 1 NC_010468.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 4097243 6068020 EcolC_3745 Escherichia coli ATCC 8739 transposase IS3/IS911 family protein YP_001726680.1 4096944 D 481805 CDS YP_001726681.1 170021727 6068630 4097240..4098106 1 NC_010468.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 4098106 6068630 EcolC_3746 Escherichia coli ATCC 8739 integrase catalytic subunit YP_001726681.1 4097240 D 481805 CDS YP_001726682.1 170021728 6068040 4099512..4100531 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfv:SFV_4229 putative oxidoreductase; alcohol dehydrogenase 4100531 6068040 EcolC_3748 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001726682.1 4099512 D 481805 CDS YP_001726683.1 170021729 6068088 4100661..4102163 1 NC_010468.1 PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: ssn:SSON_4448 hypothetical protein; hypothetical protein 4102163 6068088 EcolC_3749 Escherichia coli ATCC 8739 hypothetical protein YP_001726683.1 4100661 D 481805 CDS YP_001726684.1 170021730 6068645 complement(4102282..4103364) 1 NC_010468.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sdy:SDY_4286 hypothetical protein; YjgP/YjgQ family permease 4103364 6068645 EcolC_3750 Escherichia coli ATCC 8739 YjgP/YjgQ family permease YP_001726684.1 4102282 R 481805 CDS YP_001726685.1 170021731 6068629 complement(4103364..4104464) 1 NC_010468.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sbo:SBO_4179 hypothetical protein; YjgP/YjgQ family permease 4104464 6068629 EcolC_3751 Escherichia coli ATCC 8739 YjgP/YjgQ family permease YP_001726685.1 4103364 R 481805 CDS YP_001726686.1 170021732 6067778 4104731..4106242 1 NC_010468.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4106242 6067778 EcolC_3752 Escherichia coli ATCC 8739 leucyl aminopeptidase YP_001726686.1 4104731 D 481805 CDS YP_001726687.1 170021733 6068670 4106596..4107039 1 NC_010468.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4107039 6068670 EcolC_3753 Escherichia coli ATCC 8739 DNA polymerase III subunit chi YP_001726687.1 4106596 D 481805 CDS YP_001726688.1 170021734 6068110 4107039..4109894 1 NC_010468.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4109894 valS 6068110 valS Escherichia coli ATCC 8739 valyl-tRNA synthetase YP_001726688.1 4107039 D 481805 CDS YP_001726689.1 170021735 6068637 complement(4109950..4111146) 1 NC_010468.1 PFAM: protein of unknown function DUF898 transmembrane; KEGG: sfx:S4493 hypothetical protein; hypothetical protein 4111146 6068637 EcolC_3755 Escherichia coli ATCC 8739 hypothetical protein YP_001726689.1 4109950 R 481805 CDS YP_001726690.1 170021736 6067785 4111339..4111842 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfl:SF4233 putative acetyltransferase; N-acetyltransferase GCN5 4111842 6067785 EcolC_3756 Escherichia coli ATCC 8739 N-acetyltransferase GCN5 YP_001726690.1 4111339 D 481805 CDS YP_001726691.1 170021737 6067374 complement(4111888..4112304) 1 NC_010468.1 PFAM: protein of unknown function DUF1260; KEGG: sdy:SDY_4277 hypothetical protein; hypothetical protein 4112304 6067374 EcolC_3757 Escherichia coli ATCC 8739 hypothetical protein YP_001726691.1 4111888 R 481805 CDS YP_001726692.1 170021738 6068674 4112466..4113470 1 NC_010468.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 4113470 6068674 EcolC_3758 Escherichia coli ATCC 8739 ornithine carbamoyltransferase subunit I YP_001726692.1 4112466 D 481805 CDS YP_001726693.1 170021739 6068136 complement(4115254..4115706) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_4270 hypothetical protein; hypothetical protein 4115706 6068136 EcolC_3761 Escherichia coli ATCC 8739 hypothetical protein YP_001726693.1 4115254 R 481805 CDS YP_001726694.1 170021740 6068128 complement(4115851..4116444) 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: sfv:SFV_4244 hypothetical protein; TetR family transcriptional regulator 4116444 6068128 EcolC_3762 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001726694.1 4115851 R 481805 CDS YP_001726695.1 170021741 6067761 4116515..4117228 1 NC_010468.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sfv:SFV_4245 putative oxidoreductase; oxidoreductase 4117228 6067761 EcolC_3763 Escherichia coli ATCC 8739 oxidoreductase YP_001726695.1 4116515 D 481805 CDS YP_001726696.1 170021742 6068142 4117359..4117754 1 NC_010468.1 PFAM: Endoribonuclease L-PSP; KEGG: ssn:SSON_4428 hypothetical protein; endoribonuclease L-PSP 4117754 6068142 EcolC_3764 Escherichia coli ATCC 8739 endoribonuclease L-PSP YP_001726696.1 4117359 D 481805 CDS YP_001726697.1 170021743 6068091 4118035..4118169 1 NC_010468.1 PFAM: PyrBI operon leader peptide; KEGG: sdy:SDY_4265 pyrBI operon leader peptide; pyrBI operon leader peptide 4118169 6068091 EcolC_3765 Escherichia coli ATCC 8739 pyrBI operon leader peptide YP_001726697.1 4118035 D 481805 CDS YP_001726698.1 170021744 6064629 4118173..4119108 1 NC_010468.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4119108 pyrB 6064629 pyrB Escherichia coli ATCC 8739 aspartate carbamoyltransferase catalytic subunit YP_001726698.1 4118173 D 481805 CDS YP_001726699.1 170021745 6064662 4119121..4119582 1 NC_010468.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4119582 6064662 EcolC_3767 Escherichia coli ATCC 8739 aspartate carbamoyltransferase regulatory subunit YP_001726699.1 4119121 D 481805 CDS YP_001726700.1 170021746 6064692 4119655..4120041 1 NC_010468.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_4262 hypothetical protein; endoribonuclease L-PSP 4120041 6064692 EcolC_3768 Escherichia coli ATCC 8739 endoribonuclease L-PSP YP_001726700.1 4119655 D 481805 CDS YP_001726701.1 170021747 6065249 complement(4120247..4122943) 1 NC_010468.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4122943 6065249 EcolC_3769 Escherichia coli ATCC 8739 magnesium-transporting ATPase MgtA YP_001726701.1 4120247 R 481805 CDS YP_001726702.1 170021748 6065023 4123322..4124269 1 NC_010468.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4124269 treR 6065023 treR Escherichia coli ATCC 8739 trehalose repressor YP_001726702.1 4123322 D 481805 CDS YP_001726703.1 170021749 6065276 4124388..4125809 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4125809 6065276 EcolC_3771 Escherichia coli ATCC 8739 PTS system trehalose(maltose)-specific transporter subunit IIBC YP_001726703.1 4124388 D 481805 CDS YP_001726704.1 170021750 6065637 4125859..4127514 1 NC_010468.1 KEGG: sfx:S4513 trehalase 6-P hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; trehalose-6-phosphate hydrolase 4127514 6065637 EcolC_3772 Escherichia coli ATCC 8739 trehalose-6-phosphate hydrolase YP_001726704.1 4125859 D 481805 CDS YP_001726705.1 170021751 6066425 4127908..4130046 1 NC_010468.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4130046 6066425 EcolC_3773 Escherichia coli ATCC 8739 anaerobic ribonucleoside triphosphate reductase YP_001726705.1 4127908 D 481805 CDS YP_001726706.1 170021752 6066452 4130206..4130670 1 NC_010468.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4130670 nrdG 6066452 nrdG Escherichia coli ATCC 8739 anaerobic ribonucleotide reductase-activating protein YP_001726706.1 4130206 D 481805 CDS YP_001726707.1 170021753 6066516 complement(4130715..4131101) 1 NC_010468.1 PFAM: cytochrome b562; KEGG: sfv:SFV_4255 cytochrome b(562); cytochrome b562 4131101 6066516 EcolC_3775 Escherichia coli ATCC 8739 cytochrome b562 YP_001726707.1 4130715 R 481805 CDS YP_001726708.1 170021754 6066604 complement(4131156..4132508) 1 NC_010468.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4132508 6066604 EcolC_3776 Escherichia coli ATCC 8739 peptidase PmbA YP_001726708.1 4131156 R 481805 CDS YP_001726709.1 170021755 6066625 4132602..4133153 1 NC_010468.1 PFAM: protein of unknown function DUF615; KEGG: ssn:SSON_4415 putative alpha helix protein; hypothetical protein 4133153 6066625 EcolC_3777 Escherichia coli ATCC 8739 hypothetical protein YP_001726709.1 4132602 D 481805 CDS YP_001726710.1 170021756 6066641 complement(4133309..4134682) 1 NC_010468.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_4213 putative ligase; UDP-N-acetylmuramate 4134682 6066641 EcolC_3778 Escherichia coli ATCC 8739 UDP-N-acetylmuramate YP_001726710.1 4133309 R 481805 CDS YP_001726711.1 170021757 6066793 4134858..4135856 1 NC_010468.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4135856 6066793 EcolC_3779 Escherichia coli ATCC 8739 fructose-1,6-bisphosphatase YP_001726711.1 4134858 D 481805 CDS YP_001726712.1 170021758 6066882 complement(4135889..4136884) 1 NC_010468.1 membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4136884 6066882 EcolC_3780 Escherichia coli ATCC 8739 inner membrane ABC transporter permease YjfF YP_001726712.1 4135889 R 481805 CDS YP_001726713.1 170021759 6067637 complement(4136871..4137893) 1 NC_010468.1 PFAM: inner-membrane translocator; KEGG: ssn:SSON_4411 putative transport system permease protein; monosaccharide-transporting ATPase 4137893 6067637 EcolC_3781 Escherichia coli ATCC 8739 monosaccharide-transporting ATPase YP_001726713.1 4136871 R 481805 CDS YP_001726714.1 170021760 6067580 complement(4137907..4139409) 1 NC_010468.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_4410 putative ATP-binding component of a transport system; ABC transporter-like protein 4139409 6067580 EcolC_3782 Escherichia coli ATCC 8739 ABC transporter-like protein YP_001726714.1 4137907 R 481805 CDS YP_001726715.1 170021761 6066398 complement(4139549..4140505) 1 NC_010468.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sbo:SBO_4218 putative LacI-type transcriptional regulator; periplasmic binding protein/LacI transcriptional regulator 4140505 6066398 EcolC_3783 Escherichia coli ATCC 8739 periplasmic binding protein/LacI transcriptional regulator YP_001726715.1 4139549 R 481805 CDS YP_001726716.1 170021762 6067329 4140815..4141345 1 NC_010468.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4141345 6067329 EcolC_3784 Escherichia coli ATCC 8739 inorganic pyrophosphatase YP_001726716.1 4140815 D 481805 CDS YP_001726717.1 170021763 6066117 complement(4141725..4142066) 1 NC_010468.1 PFAM: AIG2 family protein; KEGG: sdy:SDY_4459 hypothetical protein; AIG2 family protein 4142066 6066117 EcolC_3785 Escherichia coli ATCC 8739 AIG2 family protein YP_001726717.1 4141725 R 481805 CDS YP_001726718.1 170021764 6065055 complement(4142069..4145848) 1 NC_010468.1 PFAM: protein of unknown function DUF490; KEGG: ssn:SSON_4406 hypothetical protein; hypothetical protein 4145848 6065055 EcolC_3786 Escherichia coli ATCC 8739 hypothetical protein YP_001726718.1 4142069 R 481805 CDS YP_001726719.1 170021765 6066462 complement(4145845..4147578) 1 NC_010468.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: sbo:SBO_4223 hypothetical protein; surface antigen (D15) 4147578 6066462 EcolC_3787 Escherichia coli ATCC 8739 surface antigen (D15) YP_001726719.1 4145845 R 481805 CDS YP_001726720.1 170021766 6065856 4147784..4148422 1 NC_010468.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4148422 6065856 EcolC_3788 Escherichia coli ATCC 8739 methionine sulfoxide reductase A YP_001726720.1 4147784 D 481805 CDS YP_001726721.1 170021767 6067297 4148745..4150088 1 NC_010468.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sdy:SDY_4455 putative transport protein; hypothetical protein 4150088 6067297 EcolC_3789 Escherichia coli ATCC 8739 hypothetical protein YP_001726721.1 4148745 D 481805 CDS YP_001726722.1 170021768 6067385 complement(4150150..4150356) 1 NC_010468.1 PFAM: protein of unknown function DUF1107; KEGG: sdy:SDY_4454 hypothetical protein; hypothetical protein 4150356 6067385 EcolC_3790 Escherichia coli ATCC 8739 hypothetical protein YP_001726722.1 4150150 R 481805 CDS YP_001726723.1 170021769 6067408 4150681..4151238 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_4227 hypothetical protein; hypothetical protein 4151238 6067408 EcolC_3791 Escherichia coli ATCC 8739 hypothetical protein YP_001726723.1 4150681 D 481805 CDS YP_001726724.1 170021770 6067472 complement(4151228..4151968) 1 NC_010468.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4151968 6067472 EcolC_3792 Escherichia coli ATCC 8739 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_001726724.1 4151228 R 481805 CDS YP_001726725.1 170021771 6067232 4152158..4154101 1 NC_010468.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4154101 cpdB 6067232 cpdB Escherichia coli ATCC 8739 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_001726725.1 4152158 D 481805 CDS YP_001726726.1 170021772 6067289 complement(4154224..4154604) 1 NC_010468.1 PFAM: helix-turn-helix HxlR type; KEGG: sbo:SBO_4232 hypothetical protein; HxlR family transcriptional regulator 4154604 6067289 EcolC_3794 Escherichia coli ATCC 8739 HxlR family transcriptional regulator YP_001726726.1 4154224 R 481805 CDS YP_001726727.1 170021773 6067296 4154693..4155553 1 NC_010468.1 PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sbo:SBO_4231 putative oxidoreductase; NmrA family protein 4155553 6067296 EcolC_3795 Escherichia coli ATCC 8739 NmrA family protein YP_001726727.1 4154693 D 481805 CDS YP_001726728.1 170021774 6067652 4155662..4156627 1 NC_010468.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4395 putative transmembrane subunit; hypothetical protein 4156627 6067652 EcolC_3796 Escherichia coli ATCC 8739 hypothetical protein YP_001726728.1 4155662 D 481805 CDS YP_001726729.1 170021775 6066191 4156735..4157397 1 NC_010468.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4157397 6066191 EcolC_3797 Escherichia coli ATCC 8739 iron-sulfur cluster repair di-iron protein YP_001726729.1 4156735 D 481805 CDS YP_001726730.1 170021776 6067262 complement(4157442..4158854) 1 NC_010468.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4158854 6067262 EcolC_3798 Escherichia coli ATCC 8739 D-alanine/D-serine/glycine permease YP_001726730.1 4157442 R 481805 CDS YP_001726731.1 170021777 6067626 complement(4159163..4159783) 1 NC_010468.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4159783 6067626 EcolC_3799 Escherichia coli ATCC 8739 peptidyl-prolyl cis-trans isomerase YP_001726731.1 4159163 R 481805 CDS YP_001726732.1 170021778 6066619 4160002..4160640 1 NC_010468.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sdy:SDY_4376 hypothetical protein; opacity-associated protein A 4160640 6066619 EcolC_3800 Escherichia coli ATCC 8739 opacity-associated protein A YP_001726732.1 4160002 D 481805 CDS YP_001726733.1 170021779 6066974 complement(4160624..4161271) 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: sfv:SFV_4282 hypothetical protein; TetR family transcriptional regulator 4161271 6066974 EcolC_3801 Escherichia coli ATCC 8739 TetR family transcriptional regulator YP_001726733.1 4160624 R 481805 CDS YP_001726734.1 170021780 6067343 4161484..4162275 1 NC_010468.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4162275 6067343 EcolC_3802 Escherichia coli ATCC 8739 3-ketoacyl-ACP reductase YP_001726734.1 4161484 D 481805 CDS YP_001726735.1 170021781 6067527 4162285..4163127 1 NC_010468.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sbo:SBO_4242 hypothetical protein; xylose isomerase domain-containing protein 4163127 6067527 EcolC_3803 Escherichia coli ATCC 8739 xylose isomerase domain-containing protein YP_001726735.1 4162285 D 481805 CDS YP_001726736.1 170021782 6066753 4163137..4163913 1 NC_010468.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sbo:SBO_4243 hypothetical protein; enoyl-CoA hydratase/isomerase 4163913 6066753 EcolC_3804 Escherichia coli ATCC 8739 enoyl-CoA hydratase/isomerase YP_001726736.1 4163137 D 481805 CDS YP_001726737.1 170021783 6064951 4165460..4167541 1 NC_010468.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rle:RL1831 putative oxidoreductase/dehydrogenase flavoprotein binding; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 4167541 6064951 EcolC_3806 Escherichia coli ATCC 8739 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein YP_001726737.1 4165460 D 481805 CDS YP_001726738.1 170021784 6064877 4167562..4168038 1 NC_010468.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: plu:plu0173 hypothetical protein; tripartite ATP-independent periplasmic transporter DctQ 4168038 6064877 EcolC_3807 Escherichia coli ATCC 8739 tripartite ATP-independent periplasmic transporter DctQ YP_001726738.1 4167562 D 481805 CDS YP_001726739.1 170021785 6066845 4168081..4169382 1 NC_010468.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ppr:PBPRB1879 C4-dicarboxylate transport system, putative integral membrane protein; TRAP dicarboxylate transporter subunit DctM 4169382 6066845 EcolC_3808 Escherichia coli ATCC 8739 TRAP dicarboxylate transporter subunit DctM YP_001726739.1 4168081 D 481805 CDS YP_001726740.1 170021786 6067842 4169435..4170406 1 NC_010468.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: ssn:SSON_4387 putative dicarboxylate-binding periplasmic protein; TRAP dicarboxylate transporter subunit DctP 4170406 6067842 EcolC_3809 Escherichia coli ATCC 8739 TRAP dicarboxylate transporter subunit DctP YP_001726740.1 4169435 D 481805 CDS YP_001726741.1 170021787 6067310 complement(4170520..4170969) 1 NC_010468.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4170969 rplI 6067310 rplI Escherichia coli ATCC 8739 50S ribosomal protein L9 YP_001726741.1 4170520 R 481805 CDS YP_001726742.1 170021788 6067537 complement(4171011..4171238) 1 NC_010468.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4171238 rpsR 6067537 rpsR Escherichia coli ATCC 8739 30S ribosomal protein S18 YP_001726742.1 4171011 R 481805 CDS YP_001726743.1 170021789 6064493 complement(4171243..4171557) 1 NC_010468.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4171557 6064493 EcolC_3812 Escherichia coli ATCC 8739 primosomal replication protein N YP_001726743.1 4171243 R 481805 CDS YP_001726744.1 170021790 6067273 complement(4171564..4171959) 1 NC_010468.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4171959 rpsF 6067273 rpsF Escherichia coli ATCC 8739 30S ribosomal protein S6 YP_001726744.1 4171564 R 481805 CDS YP_001726745.1 170021791 6064959 4172286..4172561 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_4255 hypothetical protein; hypothetical protein 4172561 6064959 EcolC_3814 Escherichia coli ATCC 8739 hypothetical protein YP_001726745.1 4172286 D 481805 CDS YP_001726746.1 170021792 6064755 complement(4172690..4173376) 1 NC_010468.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4173376 sgaE 6064755 sgaE Escherichia coli ATCC 8739 L-ribulose-5-phosphate 4-epimerase YP_001726746.1 4172690 R 481805 CDS YP_001726747.1 170021793 6064642 complement(4173376..4174230) 1 NC_010468.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4174230 6064642 EcolC_3816 Escherichia coli ATCC 8739 L-xylulose 5-phosphate 3-epimerase YP_001726747.1 4173376 R 481805 CDS YP_001726748.1 170021794 6064702 complement(4174240..4174890) 1 NC_010468.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4174890 ulaD 6064702 ulaD Escherichia coli ATCC 8739 3-keto-L-gulonate-6-phosphate decarboxylase YP_001726748.1 4174240 R 481805 CDS YP_001726749.1 170021795 6064829 complement(4174904..4175368) 1 NC_010468.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4175368 6064829 EcolC_3818 Escherichia coli ATCC 8739 PTS system L-ascorbate-specific transporter subunit IIA YP_001726749.1 4174904 R 481805 CDS YP_001726750.1 170021796 6064716 complement(4175378..4175683) 1 NC_010468.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4175683 6064716 EcolC_3819 Escherichia coli ATCC 8739 PTS system L-ascorbate-specific transporter subunit IIB YP_001726750.1 4175378 R 481805 CDS YP_001726751.1 170021797 6067199 complement(4175699..4177096) 1 NC_010468.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4177096 ulaA 6067199 ulaA Escherichia coli ATCC 8739 PTS system ascorbate-specific transporter subunit IIC YP_001726751.1 4175699 R 481805 CDS YP_001726752.1 170021798 6065981 4177451..4178515 1 NC_010468.1 KEGG: ssn:SSON_4374 hypothetical protein; putative L-ascorbate 6-phosphate lactonase 4178515 6065981 EcolC_3821 Escherichia coli ATCC 8739 putative L-ascorbate 6-phosphate lactonase YP_001726752.1 4177451 D 481805 CDS YP_001726753.1 170021799 6065387 4178623..4179378 1 NC_010468.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4179378 6065387 EcolC_3822 Escherichia coli ATCC 8739 transcriptional repressor UlaR YP_001726753.1 4178623 D 481805 CDS YP_001726754.1 170021800 6065192 complement(4179375..4180124) 1 NC_010468.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4180124 6065192 EcolC_3823 Escherichia coli ATCC 8739 esterase YP_001726754.1 4179375 R 481805 CDS YP_001726755.1 170021801 6064983 4180306..4180635 1 NC_010468.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A 4180635 6064983 EcolC_3824 Escherichia coli ATCC 8739 putative biofilm stress and motility protein A YP_001726755.1 4180306 D 481805 CDS YP_001726756.1 170021802 6065059 4180784..4181059 1 NC_010468.1 PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_4267 hypothetical protein; hypothetical protein 4181059 6065059 EcolC_3825 Escherichia coli ATCC 8739 hypothetical protein YP_001726756.1 4180784 D 481805 CDS YP_001726757.1 170021803 6065082 complement(4181176..4182801) 1 NC_010468.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4182801 6065082 EcolC_3826 Escherichia coli ATCC 8739 isovaleryl CoA dehydrogenase YP_001726757.1 4181176 R 481805 CDS YP_001726758.1 170021804 6065187 complement(4182885..4184048) 1 NC_010468.1 PFAM: glutathionylspermidine synthase; KEGG: sfx:S4608 putative synthetase/amidase; glutathionylspermidine synthase 4184048 6065187 EcolC_3827 Escherichia coli ATCC 8739 glutathionylspermidine synthase YP_001726758.1 4182885 R 481805 CDS YP_001726759.1 170021805 6065392 complement(4184051..4184689) 1 NC_010468.1 PFAM: protein of unknown function DUF1190; KEGG: sfv:SFV_4341 hypothetical protein; hypothetical protein 4184689 6065392 EcolC_3828 Escherichia coli ATCC 8739 hypothetical protein YP_001726759.1 4184051 R 481805 CDS YP_001726760.1 170021806 6065517 complement(4184699..4185097) 1 NC_010468.1 PFAM: protein of unknown function DUF350; KEGG: sbo:SBO_4271 hypothetical protein; hypothetical protein 4185097 6065517 EcolC_3829 Escherichia coli ATCC 8739 hypothetical protein YP_001726760.1 4184699 R 481805 CDS YP_001726761.1 170021807 6065595 complement(4185115..4185774) 1 NC_010468.1 KEGG: sbo:SBO_4272 hypothetical protein; hypothetical protein 4185774 6065595 EcolC_3830 Escherichia coli ATCC 8739 hypothetical protein YP_001726761.1 4185115 R 481805 CDS YP_001726762.1 170021808 6065766 complement(4185825..4186523) 1 NC_010468.1 PFAM: PspA/IM30 family protein; KEGG: sbo:SBO_4273 putative alpha helical protein; phage shock protein A, PspA 4186523 6065766 EcolC_3831 Escherichia coli ATCC 8739 phage shock protein A, PspA YP_001726762.1 4185825 R 481805 CDS YP_001726763.1 170021809 6065832 complement(4186542..4186943) 1 NC_010468.1 KEGG: stm:STM4370 putative cytoplasmic protein; putative cytoplasmic protein 4186943 6065832 EcolC_3832 Escherichia coli ATCC 8739 putative cytoplasmic protein YP_001726763.1 4186542 R 481805 CDS YP_001726764.1 170021810 6065899 complement(4187070..4187801) 1 NC_010468.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4187801 6065899 EcolC_3833 Escherichia coli ATCC 8739 23S rRNA (guanosine-2'-O-)-methyltransferase YP_001726764.1 4187070 R 481805 CDS YP_001726765.1 170021811 6064737 complement(4187981..4190422) 1 NC_010468.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4190422 6064737 EcolC_3834 Escherichia coli ATCC 8739 exoribonuclease R YP_001726765.1 4187981 R 481805 CDS YP_001726766.1 170021812 6066284 complement(4190461..4190886) 1 NC_010468.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4190886 6066284 EcolC_3835 Escherichia coli ATCC 8739 transcriptional repressor NsrR YP_001726766.1 4190461 R 481805 CDS YP_001726767.1 170021813 6066205 complement(4191091..4192389) 1 NC_010468.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4192389 6066205 EcolC_3836 Escherichia coli ATCC 8739 adenylosuccinate synthetase YP_001726767.1 4191091 R 481805 CDS YP_001726768.1 170021814 6066322 complement(4192493..4192690) 1 NC_010468.1 KEGG: sdy:SDY_4413 hypothetical protein; hypothetical protein 4192690 6066322 EcolC_3837 Escherichia coli ATCC 8739 hypothetical protein YP_001726768.1 4192493 R 481805 CDS YP_001726769.1 170021815 6066438 complement(4192772..4193776) 1 NC_010468.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4193776 6066438 EcolC_3838 Escherichia coli ATCC 8739 FtsH protease regulator HflC YP_001726769.1 4192772 R 481805 CDS YP_001726770.1 170021816 6066473 complement(4193779..4195038) 1 NC_010468.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4195038 6066473 EcolC_3839 Escherichia coli ATCC 8739 FtsH protease regulator HflK YP_001726770.1 4193779 R 481805 CDS YP_001726771.1 170021817 6064497 complement(4195124..4196404) 1 NC_010468.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4196404 6064497 EcolC_3840 Escherichia coli ATCC 8739 putative GTPase HflX YP_001726771.1 4195124 R 481805 CDS YP_001726772.1 170021818 6066185 complement(4196480..4196788) 1 NC_010468.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4196788 hfq 6066185 hfq Escherichia coli ATCC 8739 RNA-binding protein Hfq YP_001726772.1 4196480 R 481805 CDS YP_001726773.1 170021819 6066860 complement(4196874..4197824) 1 NC_010468.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4197824 miaA 6066860 miaA Escherichia coli ATCC 8739 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001726773.1 4196874 R 481805 CDS YP_001726774.1 170021820 6066878 complement(4197817..4199664) 1 NC_010468.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4199664 mutL 6066878 mutL Escherichia coli ATCC 8739 DNA mismatch repair protein YP_001726774.1 4197817 R 481805 CDS YP_001726775.1 170021821 6066881 complement(4199674..4201011) 1 NC_010468.1 PFAM: cell wall hydrolase/autolysin; KEGG: ssn:SSON_4354 N-acetylmuramoyl-L-alanine amidase II; N-acetylmuramoyl-l-alanine amidase II 4201011 6066881 EcolC_3844 Escherichia coli ATCC 8739 N-acetylmuramoyl-l-alanine amidase II YP_001726775.1 4199674 R 481805 CDS YP_001726776.1 170021822 6067081 complement(4201030..4201491) 1 NC_010468.1 possibly involved in cell wall synthesis; putative ATPase 4201491 6067081 EcolC_3845 Escherichia coli ATCC 8739 putative ATPase YP_001726776.1 4201030 R 481805 CDS YP_001726777.1 170021823 6066898 complement(4201463..4202995) 1 NC_010468.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: sbo:SBO_4290 hypothetical protein; hypothetical protein 4202995 6066898 EcolC_3846 Escherichia coli ATCC 8739 hypothetical protein YP_001726777.1 4201463 R 481805 CDS YP_001726778.1 170021824 6064404 4203009..4204148 1 NC_010468.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: sfv:SFV_4325 hypothetical protein; iron-sulfur cluster binding protein 4204148 6064404 EcolC_3847 Escherichia coli ATCC 8739 iron-sulfur cluster binding protein YP_001726778.1 4203009 D 481805 CDS YP_001726779.1 170021825 6067331 complement(4204927..4205472) 1 NC_010468.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4205472 6067331 EcolC_3848 Escherichia coli ATCC 8739 oligoribonuclease YP_001726779.1 4204927 R 481805 CDS YP_001726780.1 170021826 6067388 4205567..4206619 1 NC_010468.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4206619 6067388 EcolC_3849 Escherichia coli ATCC 8739 ribosome-associated GTPase YP_001726780.1 4205567 D 481805 CDS YP_001726781.1 170021827 6067211 4206716..4207684 1 NC_010468.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4207684 psd 6067211 psd Escherichia coli ATCC 8739 phosphatidylserine decarboxylase YP_001726781.1 4206716 D 481805 CDS YP_001726782.1 170021828 6067446 4207706..4211029 1 NC_010468.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_4298 putative periplasmic binding protein; hypothetical protein 4211029 6067446 EcolC_3851 Escherichia coli ATCC 8739 hypothetical protein YP_001726782.1 4207706 D 481805 CDS YP_001726783.1 170021829 6064349 complement(4211058..4211372) 1 NC_010468.1 KEGG: stm:STM4346 putative inner membrane protein; putative inner membrane protein 4211372 6064349 EcolC_3852 Escherichia coli ATCC 8739 putative inner membrane protein YP_001726783.1 4211058 R 481805 CDS YP_001726784.1 170021830 6064499 complement(4211369..4211683) 1 NC_010468.1 KEGG: spt:SPA4163 hypothetical protein; hypothetical protein 4211683 6064499 EcolC_3853 Escherichia coli ATCC 8739 hypothetical protein YP_001726784.1 4211369 R 481805 CDS YP_001726785.1 170021831 6064454 complement(4211735..4213237) 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_4434 putative transport; amino acid permease-associated protein 4213237 6064454 EcolC_3854 Escherichia coli ATCC 8739 amino acid permease-associated protein YP_001726785.1 4211735 R 481805 CDS YP_001726786.1 170021832 6067544 complement(4213456..4214433) 1 NC_010468.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4214433 6067544 EcolC_3855 Escherichia coli ATCC 8739 lysyl-tRNA synthetase YP_001726786.1 4213456 R 481805 CDS YP_001726787.1 170021833 6067558 4214758..4216566 1 NC_010468.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4216566 6067558 EcolC_3856 Escherichia coli ATCC 8739 fumarate reductase flavoprotein subunit YP_001726787.1 4214758 D 481805 CDS YP_001726788.1 170021834 6064382 4216559..4217293 1 NC_010468.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4217293 6064382 EcolC_3857 Escherichia coli ATCC 8739 fumarate reductase iron-sulfur subunit YP_001726788.1 4216559 D 481805 CDS YP_001726789.1 170021835 6064445 4217304..4217699 1 NC_010468.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4217699 6064445 EcolC_3858 Escherichia coli ATCC 8739 fumarate reductase subunit C YP_001726789.1 4217304 D 481805 CDS YP_001726790.1 170021836 6064437 4217710..4218069 1 NC_010468.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4218069 6064437 EcolC_3859 Escherichia coli ATCC 8739 fumarate reductase subunit D YP_001726790.1 4217710 D 481805 CDS YP_001726791.1 170021837 6067598 4218132..4219265 1 NC_010468.1 PFAM: beta-lactamase; KEGG: sbo:SBO_4306 beta-lactamase; beta-lactamase 4219265 ampC 6067598 ampC Escherichia coli ATCC 8739 beta-lactamase YP_001726791.1 4218132 D 481805 CDS YP_001726792.1 170021838 6067619 4219354..4219887 1 NC_010468.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4219887 6067619 EcolC_3861 Escherichia coli ATCC 8739 outer membrane lipoprotein Blc YP_001726792.1 4219354 D 481805 CDS YP_001726793.1 170021839 6067308 complement(4219884..4220201) 1 NC_010468.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4220201 6067308 EcolC_3862 Escherichia coli ATCC 8739 quaternary ammonium compound-resistance protein SugE YP_001726793.1 4219884 R 481805 CDS YP_001726794.1 170021840 6067633 complement(4220376..4220522) 1 NC_010468.1 PFAM: Entericidin EcnAB; KEGG: ssn:SSON_4333 putative toxin of osmotically regulated toxin-antitoxin system associated with programmed cell death; entericidin B membrane lipoprotein 4220522 6067633 EcolC_3863 Escherichia coli ATCC 8739 entericidin B membrane lipoprotein YP_001726794.1 4220376 R 481805 CDS YP_001726795.1 170021841 6068746 complement(4220633..4220758) 1 NC_010468.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4220758 6068746 EcolC_3864 Escherichia coli ATCC 8739 entericidin A YP_001726795.1 4220633 R 481805 CDS YP_001726796.1 170021842 6064580 complement(4220810..4221376) 1 NC_010468.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4221376 6064580 EcolC_3865 Escherichia coli ATCC 8739 elongation factor P YP_001726796.1 4220810 R 481805 CDS YP_001726797.1 170021843 6066496 4221418..4222446 1 NC_010468.1 KEGG: sfx:S4569 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 4222446 6066496 EcolC_3866 Escherichia coli ATCC 8739 lysine 2,3-aminomutase YodO family protein YP_001726797.1 4221418 D 481805 CDS YP_001726798.1 170021844 6065105 4222840..4223709 1 NC_010468.1 KEGG: sbo:SBO_4311 hypothetical protein; hypothetical protein 4223709 6065105 EcolC_3867 Escherichia coli ATCC 8739 hypothetical protein YP_001726798.1 4222840 D 481805 CDS YP_001726799.1 170021845 6064500 complement(4223912..4224265) 1 NC_010468.1 KEGG: sdy:SDY_4450 hypothetical protein; hypothetical protein 4224265 6064500 EcolC_3868 Escherichia coli ATCC 8739 hypothetical protein YP_001726799.1 4223912 R 481805 CDS YP_001726800.1 170021846 6065803 complement(4224403..4226049) 1 NC_010468.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4226049 groEL 6065803 groEL Escherichia coli ATCC 8739 chaperonin GroEL YP_001726800.1 4224403 R 481805 CDS YP_001726801.1 170021847 6064840 complement(4226093..4226386) 1 NC_010468.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4226386 groES 6064840 groES Escherichia coli ATCC 8739 co-chaperonin GroES YP_001726801.1 4226093 R 481805 CDS YP_001726802.1 170021848 6064620 4226662..4227918 1 NC_010468.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 4227918 6064620 EcolC_3871 Escherichia coli ATCC 8739 inner membrane protein YjeH YP_001726802.1 4226662 D 481805 CDS YP_001726803.1 170021849 6067443 complement(4227934..4228410) 1 NC_010468.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4228410 fxsA 6067443 fxsA Escherichia coli ATCC 8739 FxsA protein YP_001726803.1 4227934 R 481805 CDS YP_001726804.1 170021850 6065160 4228747..4230183 1 NC_010468.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4230183 aspA 6065160 aspA Escherichia coli ATCC 8739 aspartate ammonia-lyase YP_001726804.1 4228747 D 481805 CDS YP_001726805.1 170021851 6064614 4230301..4231602 1 NC_010468.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4231602 6064614 EcolC_3874 Escherichia coli ATCC 8739 anaerobic C4-dicarboxylate transporter YP_001726805.1 4230301 D 481805 CDS YP_001726806.1 170021852 6064498 4231718..4232056 1 NC_010468.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4232056 6064498 EcolC_3875 Escherichia coli ATCC 8739 divalent-cation tolerance protein CutA YP_001726806.1 4231718 D 481805 CDS YP_001726807.1 170021853 6066324 4232032..4233729 1 NC_010468.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4233729 dipZ 6066324 dipZ Escherichia coli ATCC 8739 thiol:disulfide interchange protein YP_001726807.1 4232032 D 481805 CDS YP_001726808.1 170021854 6066392 4233766..4234341 1 NC_010468.1 PFAM: regulatory protein TetR; KEGG: ssn:SSON_4318 hypothetical protein; putative transcriptional regulator 4234341 6066392 EcolC_3877 Escherichia coli ATCC 8739 putative transcriptional regulator YP_001726808.1 4233766 D 481805 CDS YP_001726809.1 170021855 6067834 4234721..4235986 1 NC_010468.1 PFAM: integrase family protein; KEGG: sfx:S4822 putative P4-type integrase; integrase family protein 4235986 6067834 EcolC_3878 Escherichia coli ATCC 8739 integrase family protein YP_001726809.1 4234721 D 481805 CDS YP_001726810.1 170021856 6064343 complement(join(4238126..4238569,4238569..4238823)) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 4238823 6064343 EcolC_3881 Escherichia coli ATCC 8739 insertion element protein YP_001726810.1 4238126 R 481805 CDS YP_001726811.1 170021857 6064344 complement(4239557..4241671) 1 NC_010468.1 PFAM: UvrD/REP helicase; KEGG: mgm:Mmc1_1352 UvrD/REP helicase; UvrD/REP helicase 4241671 6064344 EcolC_3882 Escherichia coli ATCC 8739 UvrD/REP helicase YP_001726811.1 4239557 R 481805 CDS YP_001726812.1 170021858 6064346 complement(4241668..4248009) 1 NC_010468.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: mgm:Mmc1_1353 DEAD/DEAH box helicase domain protein; helicase superfamily protein 4248009 6064346 EcolC_3883 Escherichia coli ATCC 8739 helicase superfamily protein YP_001726812.1 4241668 R 481805 CDS YP_001726813.1 170021859 6064348 complement(4248009..4252937) 1 NC_010468.1 KEGG: mgm:Mmc1_1354 hypothetical protein; hypothetical protein 4252937 6064348 EcolC_3884 Escherichia coli ATCC 8739 hypothetical protein YP_001726813.1 4248009 R 481805 CDS YP_001726814.1 170021860 6064350 complement(4252940..4255798) 1 NC_010468.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; KEGG: mgm:Mmc1_1355 helicase domain protein; helicase domain-containing protein 4255798 6064350 EcolC_3885 Escherichia coli ATCC 8739 helicase domain-containing protein YP_001726814.1 4252940 R 481805 CDS YP_001726815.1 170021861 6064351 complement(4256022..4262336) 1 NC_010468.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: lpf:lpl2494 hypothetical protein; helicase superfamily protein 4262336 6064351 EcolC_3886 Escherichia coli ATCC 8739 helicase superfamily protein YP_001726815.1 4256022 R 481805 CDS YP_001726816.1 170021862 6064354 complement(4262336..4265695) 1 NC_010468.1 KEGG: lpf:lpl2493 hypothetical protein; hypothetical protein 4265695 6064354 EcolC_3887 Escherichia coli ATCC 8739 hypothetical protein YP_001726816.1 4262336 R 481805 CDS YP_001726817.1 170021863 6064356 4265907..4267559 1 NC_010468.1 KEGG: hso:HS_0451 hypothetical protein; hypothetical protein 4267559 6064356 EcolC_3888 Escherichia coli ATCC 8739 hypothetical protein YP_001726817.1 4265907 D 481805 CDS YP_001726818.1 170021864 6064357 4267566..4268273 1 NC_010468.1 KEGG: hso:HS_0452 hypothetical protein; hypothetical protein 4268273 6064357 EcolC_3889 Escherichia coli ATCC 8739 hypothetical protein YP_001726818.1 4267566 D 481805 CDS YP_001726819.1 170021865 6064358 4268277..4269380 1 NC_010468.1 KEGG: hso:HS_0453 hypothetical protein; hypothetical protein 4269380 6064358 EcolC_3890 Escherichia coli ATCC 8739 hypothetical protein YP_001726819.1 4268277 D 481805 CDS YP_001726820.1 170021866 6064362 4269611..4269889 1 NC_010468.1 KEGG: sfv:SFV_4217 hypothetical protein; hypothetical protein 4269889 6064362 EcolC_3891 Escherichia coli ATCC 8739 hypothetical protein YP_001726820.1 4269611 D 481805 CDS YP_001726821.1 170021867 6064612 4269935..4270915 1 NC_010468.1 PFAM: transposase IS4 family protein; KEGG: kpn:KPN_pKPN3p05895 IS5 transposase; transposase IS4 family protein 4270915 6064612 EcolC_3892 Escherichia coli ATCC 8739 transposase IS4 family protein YP_001726821.1 4269935 D 481805 CDS YP_001726822.1 170021868 6064363 join(4271543..4271797,4271797..4272240) 1 NC_010468.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein 4272240 6064363 EcolC_3893 Escherichia coli ATCC 8739 insertion element protein YP_001726822.1 4271543 D 481805 CDS YP_001726823.1 170021869 6064367 4272533..4274071 1 NC_010468.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4274071 6064367 EcolC_3894 Escherichia coli ATCC 8739 DNA-binding transcriptional activator CadC YP_001726823.1 4272533 D 481805 CDS YP_001726824.1 170021870 6064368 4274436..4275770 1 NC_010468.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4275770 cadB 6064368 cadB Escherichia coli ATCC 8739 lysine/cadaverine antiporter YP_001726824.1 4274436 D 481805 CDS YP_001726825.1 170021871 6064369 4275850..4277997 1 NC_010468.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpn:KPN_00500 lysine decarboxylase 1; lysine decarboxylase 4277997 6064369 EcolC_3896 Escherichia coli ATCC 8739 lysine decarboxylase YP_001726825.1 4275850 D 481805 CDS YP_001726826.1 170021872 6064372 4278056..4279513 1 NC_010468.1 KEGG: ssn:SSON_4307 putative peptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; amino acid/peptide transporter 4279513 6064372 EcolC_3897 Escherichia coli ATCC 8739 amino acid/peptide transporter YP_001726826.1 4278056 D 481805 CDS YP_001726827.1 170021873 6064373 4279750..4281267 1 NC_010468.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4281267 6064373 EcolC_3898 Escherichia coli ATCC 8739 lysyl-tRNA synthetase YP_001726827.1 4279750 D 481805 CDS YP_001726828.1 170021874 6064374 complement(4281386..4281559) 1 NC_010468.1 KEGG: spt:SPA1272 putative inner membrane protein; putative inner membrane protein 4281559 6064374 EcolC_3899 Escherichia coli ATCC 8739 putative inner membrane protein YP_001726828.1 4281386 R 481805 CDS YP_001726829.1 170021875 6064375 complement(4282110..4282382) 1 NC_010468.1 KEGG: sdy:SDY_4240 hypothetical protein; hypothetical protein 4282382 6064375 EcolC_3900 Escherichia coli ATCC 8739 hypothetical protein YP_001726829.1 4282110 R 481805 CDS YP_001726830.1 170021876 6064376 complement(4282394..4282624) 1 NC_010468.1 PFAM: protein of unknown function DUF1271; KEGG: ssn:SSON_4303 hypothetical protein; hypothetical protein 4282624 6064376 EcolC_3901 Escherichia coli ATCC 8739 hypothetical protein YP_001726830.1 4282394 R 481805 CDS YP_001726831.1 170021877 6064377 4282805..4284436 1 NC_010468.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4284436 6064377 EcolC_3902 Escherichia coli ATCC 8739 sensory histidine kinase DcuS YP_001726831.1 4282805 D 481805 CDS YP_001726832.1 170021878 6064378 4284433..4285152 1 NC_010468.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4285152 6064378 EcolC_3903 Escherichia coli ATCC 8739 DNA-binding transcriptional activator DcuR YP_001726832.1 4284433 D 481805 CDS YP_001726833.1 170021879 6064380 4285723..4287063 1 NC_010468.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4287063 6064380 EcolC_3904 Escherichia coli ATCC 8739 anaerobic C4-dicarboxylate transporter YP_001726833.1 4285723 D 481805 CDS YP_001726834.1 170021880 6064381 4287141..4288787 1 NC_010468.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sdy:SDY_4231 fumarase B; tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta 4288787 6064381 EcolC_3905 Escherichia coli ATCC 8739 tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta YP_001726834.1 4287141 D 481805 CDS YP_001726835.1 170021881 6064383 4288910..4289539 1 NC_010468.1 KEGG: sbo:SBO_4325 hypothetical protein; hypothetical protein 4289539 6064383 EcolC_3906 Escherichia coli ATCC 8739 hypothetical protein YP_001726835.1 4288910 D 481805 CDS YP_001726836.1 170021882 6064384 complement(4289678..4291099) 1 NC_010468.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; KEGG: sfv:SFV_4110 melibiose permease II; melibiose:sodium symporter 4291099 6064384 EcolC_3907 Escherichia coli ATCC 8739 melibiose:sodium symporter YP_001726836.1 4289678 R 481805 CDS YP_001726837.1 170021883 6064385 complement(4291202..4292557) 1 NC_010468.1 PFAM: glycoside hydrolase family 4; KEGG: ssn:SSON_4294 alpha-galactosidase; glycoside hydrolase family protein 4292557 6064385 EcolC_3908 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001726837.1 4291202 R 481805 CDS YP_001726838.1 170021884 6064386 4292840..4293748 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_4145 regulator of melibiose operon; DNA-binding transcriptional regulator MelR 4293748 6064386 EcolC_3909 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator MelR YP_001726838.1 4292840 D 481805 CDS YP_001726839.1 170021885 6064388 4293944..4296214 1 NC_010468.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sdy:SDY_4094 biodegradative arginine decarboxylase; arginine decarboxylase 4296214 6064388 EcolC_3910 Escherichia coli ATCC 8739 arginine decarboxylase YP_001726839.1 4293944 D 481805 CDS YP_001726840.1 170021886 6064392 4296539..4297300 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_4097 putative AraC-type regulatory protein; AraC family transcriptional regulator 4297300 6064392 EcolC_3911 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726840.1 4296539 D 481805 CDS YP_001726841.1 170021887 6064394 4297437..4298774 1 NC_010468.1 PFAM: amino acid permease-associated region; KEGG: ssn:SSON_4290 putative amino acid/amine transport protein, cryptic; arginine:agmatin antiporter 4298774 6064394 EcolC_3912 Escherichia coli ATCC 8739 arginine:agmatin antiporter YP_001726841.1 4297437 D 481805 CDS YP_001726842.1 170021888 6064395 4298878..4300521 1 NC_010468.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein 4300521 6064395 EcolC_3913 Escherichia coli ATCC 8739 putative cell division protein YP_001726842.1 4298878 D 481805 CDS YP_001726843.1 170021889 6064397 4300518..4301186 1 NC_010468.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4301186 6064397 EcolC_3914 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator BasR YP_001726843.1 4300518 D 481805 CDS YP_001726844.1 170021890 6064398 4301187..4302287 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sbo:SBO_4139 sensor protein for BasR; sensor protein BasS/PmrB 4302287 6064398 EcolC_3915 Escherichia coli ATCC 8739 sensor protein BasS/PmrB YP_001726844.1 4301187 D 481805 CDS YP_001726845.1 170021891 6064399 complement(4302464..4303966) 1 NC_010468.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; Osmosensory transporter coiled coil; KEGG: sdy:SDY_4102 proline permease II; proline/glycine betaine transporter 4303966 6064399 EcolC_3916 Escherichia coli ATCC 8739 proline/glycine betaine transporter YP_001726845.1 4302464 R 481805 CDS YP_001726846.1 170021892 6064400 complement(4304230..4305108) 1 NC_010468.1 KEGG: sfv:SFV_4120 hypothetical protein; hypothetical protein 4305108 6064400 EcolC_3917 Escherichia coli ATCC 8739 hypothetical protein YP_001726846.1 4304230 R 481805 CDS YP_001726847.1 170021893 6064402 4307735..4308070 1 NC_010468.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: sdy:SDY_4109 hypothetical protein; hypothetical protein 4308070 6064402 EcolC_3919 Escherichia coli ATCC 8739 hypothetical protein YP_001726847.1 4307735 D 481805 CDS YP_001726848.1 170021894 6064403 4308228..4308671 1 NC_010468.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: sbo:SBO_4132 hypothetical protein; hypothetical protein 4308671 6064403 EcolC_3920 Escherichia coli ATCC 8739 hypothetical protein YP_001726848.1 4308228 D 481805 CDS YP_001726849.1 170021895 6064405 4308804..4309592 1 NC_010468.1 KEGG: ssn:SSON_4281 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; phosphonate/organophosphate ester transporter subunit 4309592 6064405 EcolC_3921 Escherichia coli ATCC 8739 phosphonate/organophosphate ester transporter subunit YP_001726849.1 4308804 D 481805 CDS YP_001726850.1 170021896 6064406 4309617..4310633 1 NC_010468.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; phosphonate ABC transporter, periplasmic phosphonate binding protein; KEGG: sbo:SBO_4130 periplasmic binding protein component of Pn transporter; phosphonate ABC transporter periplasmic phosphonate binding protein 4310633 6064406 EcolC_3922 Escherichia coli ATCC 8739 phosphonate ABC transporter periplasmic phosphonate binding protein YP_001726850.1 4309617 D 481805 CDS YP_001726851.1 170021897 6064407 4310739..4311518 1 NC_010468.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_4113 membrane channel protein component of Pn transporter; phosphonate ABC transporter inner membrane protein 4311518 6064407 EcolC_3923 Escherichia coli ATCC 8739 phosphonate ABC transporter inner membrane protein YP_001726851.1 4310739 D 481805 CDS YP_001726852.1 170021898 6064408 4311539..4312264 1 NC_010468.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4312264 6064408 EcolC_3924 Escherichia coli ATCC 8739 phosphonate metabolism transcriptional regulator PhnF YP_001726852.1 4311539 D 481805 CDS YP_001726853.1 170021899 6064410 4312265..4312717 1 NC_010468.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: ssn:SSON_4277 phosphonate metabolism; phosphonate C-P lyase system protein PhnG 4312717 6064410 EcolC_3925 Escherichia coli ATCC 8739 phosphonate C-P lyase system protein PhnG YP_001726853.1 4312265 D 481805 CDS YP_001726854.1 170021900 6064412 4312714..4313298 1 NC_010468.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: sdy:SDY_4116 phosphonate metabolism; carbon-phosphorus lyase complex subunit 4313298 phnH 6064412 phnH Escherichia coli ATCC 8739 carbon-phosphorus lyase complex subunit YP_001726854.1 4312714 D 481805 CDS YP_001726855.1 170021901 6064415 4313298..4314362 1 NC_010468.1 PFAM: phosphonate metabolism; KEGG: ssn:SSON_4275 phosphonate metabolism; phosphonate metabolism protein 4314362 6064415 EcolC_3927 Escherichia coli ATCC 8739 phosphonate metabolism protein YP_001726855.1 4313298 D 481805 CDS YP_001726856.1 170021902 6064416 4314355..4315200 1 NC_010468.1 PFAM: phosphonate metabolism PhnJ; KEGG: sbo:SBO_4124 PhnJ; phosphonate metabolism PhnJ 4315200 6064416 EcolC_3928 Escherichia coli ATCC 8739 phosphonate metabolism PhnJ YP_001726856.1 4314355 D 481805 CDS YP_001726857.1 170021903 6064417 4315197..4315955 1 NC_010468.1 KEGG: ssn:SSON_4273 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase; phosphonate C-P lyase system protein PhnK 4315955 phnK 6064417 phnK Escherichia coli ATCC 8739 phosphonate C-P lyase system protein PhnK YP_001726857.1 4315197 D 481805 CDS YP_001726858.1 170021904 6064420 4316066..4316746 1 NC_010468.1 KEGG: sdy:SDY_4120 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase; phosphonate C-P lyase system protein PhnL 4316746 6064420 EcolC_3930 Escherichia coli ATCC 8739 phosphonate C-P lyase system protein PhnL YP_001726858.1 4316066 D 481805 CDS YP_001726859.1 170021905 6064421 4316743..4317879 1 NC_010468.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ssn:SSON_4271 phosphonate metabolism; phosphonate metabolism protein PhnM 4317879 6064421 EcolC_3931 Escherichia coli ATCC 8739 phosphonate metabolism protein PhnM YP_001726859.1 4316743 D 481805 CDS YP_001726860.1 170021906 6064422 4317879..4318436 1 NC_010468.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: ssn:SSON_4270 ATP-binding component of phosphonate transport; ribose 1,5-bisphosphokinase 4318436 6064422 EcolC_3932 Escherichia coli ATCC 8739 ribose 1,5-bisphosphokinase YP_001726860.1 4317879 D 481805 CDS YP_001726861.1 170021907 6064423 4318423..4318857 1 NC_010468.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4318857 6064423 EcolC_3933 Escherichia coli ATCC 8739 aminoalkylphosphonic acid N-acetyltransferase YP_001726861.1 4318423 D 481805 CDS YP_001726862.1 170021908 6064424 4318859..4319617 1 NC_010468.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4319617 phnP 6064424 phnP Escherichia coli ATCC 8739 carbon-phosphorus lyase complex accessory protein YP_001726862.1 4318859 D 481805 CDS YP_001726863.1 170021909 6064425 complement(4319764..4320093) 1 NC_010468.1 KEGG: sbo:SBO_4117 hypothetical protein; hypothetical protein 4320093 6064425 EcolC_3935 Escherichia coli ATCC 8739 hypothetical protein YP_001726863.1 4319764 R 481805 CDS YP_001726864.1 170021910 6064429 complement(4320162..4320611) 1 NC_010468.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4320611 6064429 EcolC_3936 Escherichia coli ATCC 8739 ribose-5-phosphate isomerase B YP_001726864.1 4320162 R 481805 CDS YP_001726865.1 170021911 6064431 4320970..4321860 1 NC_010468.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4321860 6064431 EcolC_3937 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor RpiR YP_001726865.1 4320970 D 481805 CDS YP_001726866.1 170021912 6064433 4321919..4322854 1 NC_010468.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: cko:CKO_03785 hypothetical protein; D-allose transporter subunit 4322854 6064433 EcolC_3938 Escherichia coli ATCC 8739 D-allose transporter subunit YP_001726866.1 4321919 D 481805 CDS YP_001726867.1 170021913 6064434 4322981..4324513 1 NC_010468.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4324513 6064434 EcolC_3939 Escherichia coli ATCC 8739 D-allose transporter ATP-binding protein YP_001726867.1 4322981 D 481805 CDS YP_001726868.1 170021914 6064439 4324492..4325472 1 NC_010468.1 PFAM: inner-membrane translocator; KEGG: cko:CKO_03787 hypothetical protein; D-allose transporter subunit 4325472 6064439 EcolC_3940 Escherichia coli ATCC 8739 D-allose transporter subunit YP_001726868.1 4324492 D 481805 CDS YP_001726869.1 170021915 6064441 4325483..4326178 1 NC_010468.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: cko:CKO_03788 hypothetical protein; allulose-6-phosphate 3-epimerase 4326178 6064441 EcolC_3941 Escherichia coli ATCC 8739 allulose-6-phosphate 3-epimerase YP_001726869.1 4325483 D 481805 CDS YP_001726870.1 170021916 6064442 4326162..4327091 1 NC_010468.1 PFAM: ROK family protein; KEGG: cko:CKO_03789 hypothetical protein; D-allose kinase 4327091 6064442 EcolC_3942 Escherichia coli ATCC 8739 D-allose kinase YP_001726870.1 4326162 D 481805 CDS YP_001726871.1 170021917 6064452 4327364..4329349 1 NC_010468.1 PFAM: beta-lactamase domain protein; KEGG: ssn:SSON_4265 hypothetical protein; beta-lactamase domain-containing protein 4329349 6064452 EcolC_3943 Escherichia coli ATCC 8739 beta-lactamase domain-containing protein YP_001726871.1 4327364 D 481805 CDS YP_001726872.1 170021918 6064453 4329558..4329833 1 NC_010468.1 KEGG: sbo:SBO_4114 formate dehydrogenase H; formate dehydrogenase H 4329833 6064453 EcolC_3944 Escherichia coli ATCC 8739 formate dehydrogenase H YP_001726872.1 4329558 D 481805 CDS YP_001726873.1 170021919 6064455 4329852..4330883 1 NC_010468.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4330883 6064455 EcolC_3945 Escherichia coli ATCC 8739 multidrug resistance protein MdtN YP_001726873.1 4329852 D 481805 CDS YP_001726874.1 170021920 6064458 4330883..4332934 1 NC_010468.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4332934 6064458 EcolC_3946 Escherichia coli ATCC 8739 multidrug efflux system protein MdtO YP_001726874.1 4330883 D 481805 CDS YP_001726875.1 170021921 6064459 4332931..4334397 1 NC_010468.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP 4334397 6064459 EcolC_3947 Escherichia coli ATCC 8739 putative outer membrane efflux protein MdtP YP_001726875.1 4332931 D 481805 CDS YP_001726876.1 170021922 6064462 4334595..4336742 1 NC_010468.1 Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: spt:SPA4103 formate dehydrogenase H; formate dehydrogenase subunit alpha 4336742 6064462 EcolC_3948 Escherichia coli ATCC 8739 formate dehydrogenase subunit alpha YP_001726876.1 4334595 D 481805 CDS YP_001726877.1 170021923 6064463 4336836..4337525 1 NC_010468.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: ssn:SSON_4259 hypothetical protein; Sel1 domain-containing protein 4337525 6064463 EcolC_3949 Escherichia coli ATCC 8739 Sel1 domain-containing protein YP_001726877.1 4336836 D 481805 CDS YP_001726878.1 170021924 6064465 complement(4338055..4339368) 1 NC_010468.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4339368 gltP 6064465 gltP Escherichia coli ATCC 8739 glutamate/aspartate:proton symporter YP_001726878.1 4338055 R 481805 CDS YP_001726879.1 170021925 6064466 complement(4339710..4340306) 1 NC_010468.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sfv:SFV_4135 part of formate-dependent nitrite reductase complex; formate-dependent nitrite reductase complex subunit NrfG 4340306 6064466 EcolC_3951 Escherichia coli ATCC 8739 formate-dependent nitrite reductase complex subunit NrfG YP_001726879.1 4339710 R 481805 CDS YP_001726880.1 170021926 6064468 complement(4340303..4340686) 1 NC_010468.1 TIGRFAM: cytochrome c nitrite reductase, accessory protein NrfF; PFAM: cytochrome C biogenesis protein; KEGG: sbo:SBO_4106 NrfG; formate-dependent nitrite reductase complex subunit NrfF 4340686 6064468 EcolC_3952 Escherichia coli ATCC 8739 formate-dependent nitrite reductase complex subunit NrfF YP_001726880.1 4340303 R 481805 CDS YP_001726881.1 170021927 6064469 complement(4340679..4342301) 1 NC_010468.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4342301 6064469 EcolC_3953 Escherichia coli ATCC 8739 heme lyase subunit NrfE YP_001726881.1 4340679 R 481805 CDS YP_001726882.1 170021928 6064470 complement(4342417..4343373) 1 NC_010468.1 TIGRFAM: cytochrome c nitrite reductase, NrfD subunit; PFAM: Polysulphide reductase NrfD; KEGG: ssn:SSON_4254 formate-dependent nitrate reductase complex transmembrane protein; cytochrome c nitrite reductase subunit NrfD 4343373 6064470 EcolC_3954 Escherichia coli ATCC 8739 cytochrome c nitrite reductase subunit NrfD YP_001726882.1 4342417 R 481805 CDS YP_001726883.1 170021929 6064471 complement(4343370..4344041) 1 NC_010468.1 TIGRFAM: cytochrome c nitrite reductase, Fe-S protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_4103 formate-dependent nitrite reductase complex Fe-S centers; cytochrome c nitrite reductase, Fe-S protein 4344041 6064471 EcolC_3955 Escherichia coli ATCC 8739 cytochrome c nitrite reductase, Fe-S protein YP_001726883.1 4343370 R 481805 CDS YP_001726884.1 170021930 6064472 complement(4344038..4344604) 1 NC_010468.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4344604 6064472 EcolC_3956 Escherichia coli ATCC 8739 cytochrome c nitrite reductase pentaheme subunit YP_001726884.1 4344038 R 481805 CDS YP_001726885.1 170021931 6064480 complement(4344649..4346085) 1 NC_010468.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4346085 nrfA 6064480 nrfA Escherichia coli ATCC 8739 cytochrome c552 YP_001726885.1 4344649 R 481805 CDS YP_001726886.1 170021932 6064481 4346478..4348436 1 NC_010468.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4348436 6064481 EcolC_3958 Escherichia coli ATCC 8739 acetyl-CoA synthetase YP_001726886.1 4346478 D 481805 CDS YP_001726887.1 170021933 6064482 4348637..4348951 1 NC_010468.1 PFAM: protein of unknown function DUF485; KEGG: sbo:SBO_4099 hypothetical protein; hypothetical protein 4348951 6064482 EcolC_3959 Escherichia coli ATCC 8739 hypothetical protein YP_001726887.1 4348637 D 481805 CDS YP_001726888.1 170021934 6064485 4348948..4350597 1 NC_010468.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4350597 actP 6064485 actP Escherichia coli ATCC 8739 acetate permease YP_001726888.1 4348948 D 481805 CDS YP_001726889.1 170021935 6064488 4351067..4352068 1 NC_010468.1 PFAM: pentapeptide repeat protein; KEGG: sfx:S3593 hypothetical protein; pentapeptide repeat-containing protein 4352068 6064488 EcolC_3961 Escherichia coli ATCC 8739 pentapeptide repeat-containing protein YP_001726889.1 4351067 D 481805 CDS YP_001726890.1 170021936 6064489 complement(4352222..4353871) 1 NC_010468.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: sdy:SDY_4502 hypothetical protein; Na+/H+ antiporter 4353871 6064489 EcolC_3962 Escherichia coli ATCC 8739 Na+/H+ antiporter YP_001726890.1 4352222 R 481805 CDS YP_001726891.1 170021937 6064490 complement(4354023..4355372) 1 NC_010468.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sdy:SDY_4503 hypothetical protein; xanthine/uracil/vitamin C permease 4355372 6064490 EcolC_3963 Escherichia coli ATCC 8739 xanthine/uracil/vitamin C permease YP_001726891.1 4354023 R 481805 CDS YP_001726892.1 170021938 6064495 complement(4355918..4356382) 1 NC_010468.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sdy:SDY_4504 redox-sensing activator of SoxS; MerR family transcriptional regulator 4356382 6064495 EcolC_3964 Escherichia coli ATCC 8739 MerR family transcriptional regulator YP_001726892.1 4355918 R 481805 CDS YP_001726893.1 170021939 6064496 4356468..4356791 1 NC_010468.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4356791 6064496 EcolC_3965 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator SoxS YP_001726893.1 4356468 D 481805 CDS YP_001726894.1 170021940 6064501 complement(4356794..4358380) 1 NC_010468.1 PFAM: EAL domain protein; KEGG: sfv:SFV_4151 hypothetical protein; EAL domain-containing protein 4358380 6064501 EcolC_3966 Escherichia coli ATCC 8739 EAL domain-containing protein YP_001726894.1 4356794 R 481805 CDS YP_001726895.1 170021941 6064502 4358810..4359091 1 NC_010468.1 KEGG: sbo:SBO_4092 hypothetical protein; hypothetical protein 4359091 6064502 EcolC_3967 Escherichia coli ATCC 8739 hypothetical protein YP_001726895.1 4358810 D 481805 CDS YP_001726896.1 170021942 6064503 complement(4359190..4359726) 1 NC_010468.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4359726 6064503 EcolC_3968 Escherichia coli ATCC 8739 single-stranded DNA-binding protein YP_001726896.1 4359190 R 481805 CDS YP_001726897.1 170021943 6064504 4359981..4362803 1 NC_010468.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4362803 uvrA 6064504 uvrA Escherichia coli ATCC 8739 excinuclease ABC subunit A YP_001726897.1 4359981 D 481805 CDS YP_001726898.1 170021944 6064505 complement(4362838..4363194) 1 NC_010468.1 PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_4510 hypothetical protein; hypothetical protein 4363194 6064505 EcolC_3970 Escherichia coli ATCC 8739 hypothetical protein YP_001726898.1 4362838 R 481805 CDS YP_001726899.1 170021945 6064506 complement(4363198..4363614) 1 NC_010468.1 PFAM: protein of unknown function UPF0047; KEGG: sdy:SDY_4511 hypothetical protein; hypothetical protein 4363614 6064506 EcolC_3971 Escherichia coli ATCC 8739 hypothetical protein YP_001726899.1 4363198 R 481805 CDS YP_001726900.1 170021946 6064507 complement(4363725..4364438) 1 NC_010468.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4364438 aphA 6064507 aphA Escherichia coli ATCC 8739 acid phosphatase/phosphotransferase YP_001726900.1 4363725 R 481805 CDS YP_001726901.1 170021947 6064509 4364840..4365226 1 NC_010468.1 KEGG: sbo:SBO_4083 hypothetical protein; hypothetical protein 4365226 6064509 EcolC_3973 Escherichia coli ATCC 8739 hypothetical protein YP_001726901.1 4364840 D 481805 CDS YP_001726902.1 170021948 6064510 complement(4365565..4366758) 1 NC_010468.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4366758 6064510 EcolC_3974 Escherichia coli ATCC 8739 aromatic amino acid aminotransferase YP_001726902.1 4365565 R 481805 CDS YP_001726903.1 170021949 6064511 complement(4367011..4368090) 1 NC_010468.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4368090 alr 6064511 alr Escherichia coli ATCC 8739 alanine racemase YP_001726903.1 4367011 R 481805 CDS YP_001726904.1 170021950 6064512 complement(4368143..4369558) 1 NC_010468.1 unwinds double stranded DNA; replicative DNA helicase 4369558 6064512 EcolC_3976 Escherichia coli ATCC 8739 replicative DNA helicase YP_001726904.1 4368143 R 481805 CDS YP_001726905.1 170021951 6064513 4369641..4370624 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_4523 quinone oxidoreductase; NADPH-dependent quinone oxidoreductase 4370624 6064513 EcolC_3977 Escherichia coli ATCC 8739 NADPH-dependent quinone oxidoreductase YP_001726905.1 4369641 D 481805 CDS YP_001726906.1 170021952 6064514 complement(4370790..4371032) 1 NC_010468.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4371032 pspG 6064514 pspG Escherichia coli ATCC 8739 phage shock protein G YP_001726906.1 4370790 R 481805 CDS YP_001726907.1 170021953 6064516 complement(4371166..4372203) 1 NC_010468.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: ssn:SSON_4229 hypothetical protein; tRNA-dihydrouridine synthase A 4372203 6064516 EcolC_3979 Escherichia coli ATCC 8739 tRNA-dihydrouridine synthase A YP_001726907.1 4371166 R 481805 CDS YP_001726908.1 170021954 6064519 complement(4372566..4373312) 1 NC_010468.1 KEGG: sfv:SFV_4165 hypothetical protein; hypothetical protein 4373312 6064519 EcolC_3980 Escherichia coli ATCC 8739 hypothetical protein YP_001726908.1 4372566 R 481805 CDS YP_001726909.1 170021955 6064520 complement(4373303..4373587) 1 NC_010468.1 KEGG: sfl:SF4158 hypothetical protein; hypothetical protein 4373587 6064520 EcolC_3981 Escherichia coli ATCC 8739 hypothetical protein YP_001726909.1 4373303 R 481805 CDS YP_001726910.1 170021956 6064524 4373906..4374421 1 NC_010468.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4374421 6064524 EcolC_3982 Escherichia coli ATCC 8739 zinc uptake transcriptional repressor YP_001726910.1 4373906 D 481805 CDS YP_001726911.1 170021957 6064525 complement(4374463..4374672) 1 NC_010468.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4374672 6064525 EcolC_3983 Escherichia coli ATCC 8739 putative stress-response protein YP_001726911.1 4374463 R 481805 CDS YP_001726912.1 170021958 6064527 complement(4374788..4376167) 1 NC_010468.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sfv:SFV_4169 DNA-damage-inducible protein F; DNA-damage-inducible SOS response protein 4376167 6064527 EcolC_3984 Escherichia coli ATCC 8739 DNA-damage-inducible SOS response protein YP_001726912.1 4374788 R 481805 CDS YP_001726913.1 170021959 6064528 complement(4376186..4376794) 1 NC_010468.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4376794 6064528 EcolC_3985 Escherichia coli ATCC 8739 LexA repressor YP_001726913.1 4376186 R 481805 CDS YP_001726914.1 170021960 6064529 complement(4376904..4377272) 1 NC_010468.1 PFAM: diacylglycerol kinase; KEGG: sdy:SDY_4532 diacylglycerol kinase; diacylglycerol kinase 4377272 6064529 EcolC_3986 Escherichia coli ATCC 8739 diacylglycerol kinase YP_001726914.1 4376904 R 481805 CDS YP_001726915.1 170021961 6064530 4377443..4379866 1 NC_010468.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4379866 6064530 EcolC_3987 Escherichia coli ATCC 8739 glycerol-3-phosphate acyltransferase YP_001726915.1 4377443 D 481805 CDS YP_001726916.1 170021962 6064531 complement(4380021..4380893) 1 NC_010468.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4380893 ubiA 6064531 ubiA Escherichia coli ATCC 8739 4-hydroxybenzoate octaprenyltransferase YP_001726916.1 4380021 R 481805 CDS YP_001726917.1 170021963 6064533 complement(4380906..4381403) 1 NC_010468.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4381403 ubiC 6064533 ubiC Escherichia coli ATCC 8739 chorismate pyruvate lyase YP_001726917.1 4380906 R 481805 CDS YP_001726918.1 170021964 6064535 complement(4383435..4384355) 1 NC_010468.1 PFAM: Maltose operon periplasmic; KEGG: ssn:SSON_4215 periplasmic protein of mal regulon; maltose regulon periplasmic protein 4384355 6064535 EcolC_3992 Escherichia coli ATCC 8739 maltose regulon periplasmic protein YP_001726918.1 4383435 R 481805 CDS YP_001726919.1 170021965 6064537 complement(4384598..4385938) 1 NC_010468.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4385938 lamB 6064537 lamB Escherichia coli ATCC 8739 maltoporin YP_001726919.1 4384598 R 481805 CDS YP_001726920.1 170021966 6064539 complement(4386010..4387125) 1 NC_010468.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4387125 6064539 EcolC_3994 Escherichia coli ATCC 8739 maltose/maltodextrin transporter ATP-binding protein YP_001726920.1 4386010 R 481805 CDS YP_001726921.1 170021967 6064542 4387490..4388680 1 NC_010468.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4388680 malE 6064542 malE Escherichia coli ATCC 8739 maltose ABC transporter periplasmic protein YP_001726921.1 4387490 D 481805 CDS YP_001726922.1 170021968 6064546 4388834..4390378 1 NC_010468.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4390378 malF 6064546 malF Escherichia coli ATCC 8739 maltose transporter membrane protein YP_001726922.1 4388834 D 481805 CDS YP_001726923.1 170021969 6064547 4390393..4391283 1 NC_010468.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4391283 malG 6064547 malG Escherichia coli ATCC 8739 maltose transporter permease YP_001726923.1 4390393 D 481805 CDS YP_001726924.1 170021970 6064548 4391655..4393130 1 NC_010468.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 4393130 xylE 6064548 xylE Escherichia coli ATCC 8739 D-xylose transporter XylE YP_001726924.1 4391655 D 481805 CDS YP_001726925.1 170021971 6064550 complement(4393174..4393584) 1 NC_010468.1 PFAM: phosphate-starvation-inducible E; KEGG: sdy:SDY_4218 hypothetical protein; phosphate-starvation-inducible protein PsiE 4393584 6064550 EcolC_3999 Escherichia coli ATCC 8739 phosphate-starvation-inducible protein PsiE YP_001726925.1 4393174 R 481805 CDS YP_001726926.1 170021972 6064551 complement(4394014..4394175) 1 NC_010468.1 hypothetical protein 4394175 6064551 EcolC_4000 Escherichia coli ATCC 8739 hypothetical protein YP_001726926.1 4394014 R 481805 CDS YP_001726927.1 170021973 6064552 complement(4394179..4396275) 1 NC_010468.1 PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: sbo:SBO_4057 hypothetical protein; hypothetical protein 4396275 6064552 EcolC_4001 Escherichia coli ATCC 8739 hypothetical protein YP_001726927.1 4394179 R 481805 CDS YP_001726928.1 170021974 6064554 complement(4396275..4397012) 1 NC_010468.1 PFAM: protein of unknown function DUF1017; KEGG: sdy:SDY_4220 hypothetical protein; hypothetical protein 4397012 6064554 EcolC_4002 Escherichia coli ATCC 8739 hypothetical protein YP_001726928.1 4396275 R 481805 CDS YP_001726929.1 170021975 6064556 complement(4397009..4397647) 1 NC_010468.1 KEGG: ssn:SSON_4205 hypothetical protein; hypothetical protein 4397647 6064556 EcolC_4003 Escherichia coli ATCC 8739 hypothetical protein YP_001726929.1 4397009 R 481805 CDS YP_001726930.1 170021976 6064557 complement(4397762..4398004) 1 NC_010468.1 KEGG: sdy:SDY_4222 hypothetical protein; hypothetical protein 4398004 6064557 EcolC_4004 Escherichia coli ATCC 8739 hypothetical protein YP_001726930.1 4397762 R 481805 CDS YP_001726931.1 170021977 6064558 complement(4398516..4400165) 1 NC_010468.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4400165 pgi 6064558 pgi Escherichia coli ATCC 8739 glucose-6-phosphate isomerase YP_001726931.1 4398516 R 481805 CDS YP_001726932.1 170021978 6064559 4400690..4402039 1 NC_010468.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4402039 6064559 EcolC_4006 Escherichia coli ATCC 8739 aspartate kinase III YP_001726932.1 4400690 D 481805 CDS YP_001726933.1 170021979 6064560 4402292..4402564 1 NC_010468.1 KEGG: sdy:SDY_4309 hypothetical protein; hypothetical protein 4402564 6064560 EcolC_4007 Escherichia coli ATCC 8739 hypothetical protein YP_001726933.1 4402292 D 481805 CDS YP_001726934.1 170021980 6064561 complement(4402697..4403569) 1 NC_010468.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4403569 6064561 EcolC_4008 Escherichia coli ATCC 8739 23S rRNA pseudouridine synthase F YP_001726934.1 4402697 R 481805 CDS YP_001726935.1 170021981 6064563 4403781..4404470 1 NC_010468.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4404470 6064563 EcolC_4009 Escherichia coli ATCC 8739 peptidase E YP_001726935.1 4403781 D 481805 CDS YP_001726936.1 170021982 6064565 complement(4404561..4406192) 1 NC_010468.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; KEGG: ssn:SSON_4191 putative alpha helix protein; sodium-dependent inorganic phosphate (Pi) transporter 4406192 6064565 EcolC_4010 Escherichia coli ATCC 8739 sodium-dependent inorganic phosphate (Pi) transporter YP_001726936.1 4404561 R 481805 CDS YP_001726937.1 170021983 6064566 complement(4406412..4410095) 1 NC_010468.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4410095 metH 6064566 metH Escherichia coli ATCC 8739 B12-dependent methionine synthase YP_001726937.1 4406412 R 481805 CDS YP_001726938.1 170021984 6064567 4410295..4411119 1 NC_010468.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4411119 6064567 EcolC_4012 Escherichia coli ATCC 8739 IclR family transcriptional regulator YP_001726938.1 4410295 D 481805 CDS YP_001726939.1 170021985 6064568 4411436..4413010 1 NC_010468.1 PFAM: ShET2 enterotoxin domain protein; KEGG: yps:YPTB3305 enterotoxin-like protein; ShET2 enterotoxin domain-containing protein 4413010 6064568 EcolC_4013 Escherichia coli ATCC 8739 ShET2 enterotoxin domain-containing protein YP_001726939.1 4411436 D 481805 CDS YP_001726940.1 170021986 6064569 complement(4412979..4414715) 1 NC_010468.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4414715 aceK 6064569 aceK Escherichia coli ATCC 8739 bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_001726940.1 4412979 R 481805 CDS YP_001726941.1 170021987 6064570 complement(4414996..4416300) 1 NC_010468.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sdy:SDY_4328 isocitrate lyase; isocitrate lyase 4416300 6064570 EcolC_4015 Escherichia coli ATCC 8739 isocitrate lyase YP_001726941.1 4414996 R 481805 CDS YP_001726942.1 170021988 6064573 complement(4416330..4417931) 1 NC_010468.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4417931 6064573 EcolC_4016 Escherichia coli ATCC 8739 malate synthase YP_001726942.1 4416330 R 481805 CDS YP_001726943.1 170021989 6064575 complement(4418200..4419129) 1 NC_010468.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4419129 6064575 EcolC_4017 Escherichia coli ATCC 8739 homoserine O-succinyltransferase YP_001726943.1 4418200 R 481805 CDS YP_001726944.1 170021990 6064576 4419286..4419729 1 NC_010468.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_4083 hypothetical protein; hypothetical protein 4419729 6064576 EcolC_4018 Escherichia coli ATCC 8739 hypothetical protein YP_001726944.1 4419286 D 481805 CDS YP_001726945.1 170021991 6064586 4425743..4427332 1 NC_010468.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4427332 purH 6064586 purH Escherichia coli ATCC 8739 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001726945.1 4425743 D 481805 CDS YP_001726946.1 170021992 6064592 4427344..4428633 1 NC_010468.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4428633 6064592 EcolC_4020 Escherichia coli ATCC 8739 phosphoribosylamine--glycine ligase YP_001726946.1 4427344 D 481805 CDS YP_001726947.1 170021993 6064594 complement(4428630..4429955) 1 NC_010468.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4429955 6064594 EcolC_4021 Escherichia coli ATCC 8739 transcriptional regulatory protein ZraR YP_001726947.1 4428630 R 481805 CDS YP_001726948.1 170021994 6064595 complement(4429952..4431328) 1 NC_010468.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfx:S3660 sensor kinase for HydG, hydrogenase 3 activity; sensor protein ZraS 4431328 6064595 EcolC_4022 Escherichia coli ATCC 8739 sensor protein ZraS YP_001726948.1 4429952 R 481805 CDS YP_001726949.1 170021995 6064596 4431566..4431985 1 NC_010468.1 KEGG: sdy:SDY_3724 hypothetical protein; zinc resistance protein 4431985 zraP 6064596 zraP Escherichia coli ATCC 8739 zinc resistance protein YP_001726949.1 4431566 D 481805 CDS YP_001726950.1 170021996 6064599 complement(4431987..4432622) 1 NC_010468.1 PFAM: protein of unknown function DUF1481; KEGG: sdy:SDY_3725 hypothetical protein; hypothetical protein 4432622 6064599 EcolC_4024 Escherichia coli ATCC 8739 hypothetical protein YP_001726950.1 4431987 R 481805 CDS YP_001726951.1 170021997 6064600 complement(4432695..4432967) 1 NC_010468.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4432967 6064600 EcolC_4025 Escherichia coli ATCC 8739 transcriptional regulator HU subunit alpha YP_001726951.1 4432695 R 481805 CDS YP_001726952.1 170021998 6064601 complement(4433154..4433744) 1 NC_010468.1 PFAM: protein of unknown function DUF416; KEGG: ssn:SSON_4172 hypothetical protein; hypothetical protein 4433744 6064601 EcolC_4026 Escherichia coli ATCC 8739 hypothetical protein YP_001726952.1 4433154 R 481805 CDS YP_001726953.1 170021999 6064618 complement(4433787..4434458) 1 NC_010468.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4434458 6064618 EcolC_4027 Escherichia coli ATCC 8739 endonuclease V YP_001726953.1 4433787 R 481805 CDS YP_001726954.1 170022000 6064627 complement(4434468..4435532) 1 NC_010468.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4435532 hemE 6064627 hemE Escherichia coli ATCC 8739 uroporphyrinogen decarboxylase YP_001726954.1 4434468 R 481805 CDS YP_001726955.1 170022001 6064634 complement(4435572..4436345) 1 NC_010468.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4436345 nudC 6064634 nudC Escherichia coli ATCC 8739 NADH pyrophosphatase YP_001726955.1 4435572 R 481805 CDS YP_001726956.1 170022002 6064635 4436440..4436916 1 NC_010468.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4436916 6064635 EcolC_4030 Escherichia coli ATCC 8739 anti-RNA polymerase sigma 70 factor YP_001726956.1 4436440 D 481805 CDS YP_001726957.1 170022003 6064650 4437150..4439045 1 NC_010468.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4439045 6064650 EcolC_4031 Escherichia coli ATCC 8739 thiamine biosynthesis protein ThiC YP_001726957.1 4437150 D 481805 CDS YP_001726958.1 170022004 6064671 4439045..4439680 1 NC_010468.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4439680 6064671 EcolC_4032 Escherichia coli ATCC 8739 thiamine-phosphate pyrophosphorylase YP_001726958.1 4439045 D 481805 CDS YP_001726959.1 170022005 6064697 4439673..4440428 1 NC_010468.1 TIGRFAM: thiazole biosynthesis adenylyltransferase ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sfv:SFV_4064 thiamin biosynthesis, thiazole moiety; thiazole biosynthesis adenylyltransferase ThiF 4440428 6064697 EcolC_4033 Escherichia coli ATCC 8739 thiazole biosynthesis adenylyltransferase ThiF YP_001726959.1 4439673 D 481805 CDS YP_001726960.1 170022006 6064708 4440412..4440612 1 NC_010468.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4440612 6064708 EcolC_4034 Escherichia coli ATCC 8739 sulfur carrier protein ThiS YP_001726960.1 4440412 D 481805 CDS YP_001726961.1 170022007 6064712 4440614..4441384 1 NC_010468.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4441384 thiG 6064712 thiG Escherichia coli ATCC 8739 thiazole synthase YP_001726961.1 4440614 D 481805 CDS YP_001726962.1 170022008 6064718 4441381..4442514 1 NC_010468.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4442514 thiH 6064718 thiH Escherichia coli ATCC 8739 thiamine biosynthesis protein ThiH YP_001726962.1 4441381 D 481805 CDS YP_001726963.1 170022009 6064719 complement(4442756..4446979) 1 NC_010468.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4446979 6064719 EcolC_4037 Escherichia coli ATCC 8739 DNA-directed RNA polymerase subunit beta' YP_001726963.1 4442756 R 481805 CDS YP_001726964.1 170022010 6064720 complement(4447056..4451084) 1 NC_010468.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4451084 rpoB 6064720 rpoB Escherichia coli ATCC 8739 DNA-directed RNA polymerase subunit beta YP_001726964.1 4447056 R 481805 CDS YP_001726965.1 170022011 6064731 complement(4451404..4451769) 1 NC_010468.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4451769 rplL 6064731 rplL Escherichia coli ATCC 8739 50S ribosomal protein L7/L12 YP_001726965.1 4451404 R 481805 CDS YP_001726966.1 170022012 6064740 complement(4451836..4452333) 1 NC_010468.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4452333 rplJ 6064740 rplJ Escherichia coli ATCC 8739 50S ribosomal protein L10 YP_001726966.1 4451836 R 481805 CDS YP_001726967.1 170022013 6064743 complement(4452746..4453450) 1 NC_010468.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4453450 rplA 6064743 rplA Escherichia coli ATCC 8739 50S ribosomal protein L1 YP_001726967.1 4452746 R 481805 CDS YP_001726968.1 170022014 6064748 complement(4453454..4453882) 1 NC_010468.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4453882 rplK 6064748 rplK Escherichia coli ATCC 8739 50S ribosomal protein L11 YP_001726968.1 4453454 R 481805 CDS YP_001726969.1 170022015 6064756 complement(4454041..4454586) 1 NC_010468.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4454586 nusG 6064756 nusG Escherichia coli ATCC 8739 transcription antitermination protein NusG YP_001726969.1 4454041 R 481805 CDS YP_001726970.1 170022016 6064757 complement(4454588..4454971) 1 NC_010468.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4454971 secE 6064757 secE Escherichia coli ATCC 8739 preprotein translocase subunit SecE YP_001726970.1 4454588 R 481805 CDS YP_001726971.1 170022017 6064769 complement(4455201..4456385) 1 NC_010468.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4456385 6064769 EcolC_4045 Escherichia coli ATCC 8739 elongation factor Tu YP_001726971.1 4455201 R 481805 CDS YP_001726972.1 170022018 6064950 4457327..4458253 1 NC_010468.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4458253 6064950 EcolC_4046 Escherichia coli ATCC 8739 pantothenate kinase YP_001726972.1 4457327 D 481805 CDS YP_001726973.1 170022019 6065006 complement(4458282..4459247) 1 NC_010468.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4459247 6065006 EcolC_4047 Escherichia coli ATCC 8739 biotin--protein ligase YP_001726973.1 4458282 R 481805 CDS YP_001726974.1 170022020 6065008 complement(4459244..4460272) 1 NC_010468.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4460272 murB 6065008 murB Escherichia coli ATCC 8739 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001726974.1 4459244 R 481805 CDS YP_001726975.1 170022021 6065124 complement(4465789..4466577) 1 NC_010468.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4466577 6065124 EcolC_4049 Escherichia coli ATCC 8739 glutamate racemase YP_001726975.1 4465789 R 481805 CDS YP_001726976.1 170022022 6065161 complement(4466591..4468435) 1 NC_010468.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4468435 btuB 6065161 btuB Escherichia coli ATCC 8739 vitamin B12/cobalamin outer membrane transporter YP_001726976.1 4466591 R 481805 CDS YP_001726977.1 170022023 6065170 4468804..4469904 1 NC_010468.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4469904 6065170 EcolC_4051 Escherichia coli ATCC 8739 tRNA (uracil-5-)-methyltransferase YP_001726977.1 4468804 D 481805 CDS YP_001726978.1 170022024 6065188 complement(4469944..4470303) 1 NC_010468.1 PFAM: protein of unknown function DUF1422; KEGG: sbo:SBO_3983 hypothetical protein; hypothetical protein 4470303 6065188 EcolC_4052 Escherichia coli ATCC 8739 hypothetical protein YP_001726978.1 4469944 R 481805 CDS YP_001726979.1 170022025 6065202 complement(4470303..4471007) 1 NC_010468.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4471007 6065202 EcolC_4053 Escherichia coli ATCC 8739 DNA-binding transcriptional repressor FabR YP_001726979.1 4470303 R 481805 CDS YP_001726980.1 170022026 6065209 4471284..4472684 1 NC_010468.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4472684 6065209 EcolC_4054 Escherichia coli ATCC 8739 soluble pyridine nucleotide transhydrogenase YP_001726980.1 4471284 D 481805 CDS YP_001726981.1 170022027 6065212 complement(4472667..4473584) 1 NC_010468.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4473584 6065212 EcolC_4055 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator OxyR YP_001726981.1 4472667 R 481805 CDS YP_001726982.1 170022028 6065213 complement(4473851..4475224) 1 NC_010468.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4475224 6065213 EcolC_4056 Escherichia coli ATCC 8739 argininosuccinate lyase YP_001726982.1 4473851 R 481805 CDS YP_001726983.1 170022029 6065225 complement(4475285..4476058) 1 NC_010468.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4476058 6065225 EcolC_4057 Escherichia coli ATCC 8739 acetylglutamate kinase YP_001726983.1 4475285 R 481805 CDS YP_001726984.1 170022030 6065244 complement(4476069..4477073) 1 NC_010468.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4477073 argC 6065244 argC Escherichia coli ATCC 8739 N-acetyl-gamma-glutamyl-phosphate reductase YP_001726984.1 4476069 R 481805 CDS YP_001726985.1 170022031 6065263 4477227..4478378 1 NC_010468.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4478378 6065263 EcolC_4059 Escherichia coli ATCC 8739 acetylornithine deacetylase YP_001726985.1 4477227 D 481805 CDS YP_001726986.1 170022032 6065269 4478730..4481381 1 NC_010468.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4481381 6065269 EcolC_4060 Escherichia coli ATCC 8739 phosphoenolpyruvate carboxylase YP_001726986.1 4478730 D 481805 CDS YP_001726987.1 170022033 6065290 4481563..4483296 1 NC_010468.1 PFAM: sulfatase; KEGG: sbo:SBO_3974 hypothetical protein; hypothetical protein 4483296 6065290 EcolC_4061 Escherichia coli ATCC 8739 hypothetical protein YP_001726987.1 4481563 D 481805 CDS YP_001726988.1 170022034 6065316 4483511..4484362 1 NC_010468.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_3973 putative AraC-type regulatory protein; AraC family transcriptional regulator 4484362 6065316 EcolC_4062 Escherichia coli ATCC 8739 AraC family transcriptional regulator YP_001726988.1 4483511 D 481805 CDS YP_001726989.1 170022035 6065319 complement(4484349..4484690) 1 NC_010468.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative PTS system fructose-specific transporter subunit IIB 4484690 6065319 EcolC_4063 Escherichia coli ATCC 8739 putative PTS system fructose-specific transporter subunit IIB YP_001726989.1 4484349 R 481805 CDS YP_001726990.1 170022036 6065334 complement(4484692..4485570) 1 NC_010468.1 KEGG: sdy:SDY_3787 probable pyruvate formate lyase activating enzyme 2; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein; pyruvate formate lyase II activase 4485570 6065334 EcolC_4064 Escherichia coli ATCC 8739 pyruvate formate lyase II activase YP_001726990.1 4484692 R 481805 CDS YP_001726991.1 170022037 6065346 complement(4485536..4487833) 1 NC_010468.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4487833 pflD 6065346 pflD Escherichia coli ATCC 8739 putative formate acetyltransferase 2 YP_001726991.1 4485536 R 481805 CDS YP_001726992.1 170022038 6065348 complement(4487884..4488204) 1 NC_010468.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4488204 6065348 EcolC_4066 Escherichia coli ATCC 8739 putative PTS system fructose-like transporter subunit EIIB YP_001726992.1 4487884 R 481805 CDS YP_001726993.1 170022039 6065353 complement(4488219..4489298) 1 NC_010468.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative PTS system fructose-specific permease IIC 4489298 6065353 EcolC_4067 Escherichia coli ATCC 8739 putative PTS system fructose-specific permease IIC YP_001726993.1 4488219 R 481805 CDS YP_001726994.1 170022040 6065356 4489607..4492108 1 NC_010468.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: cko:CKO_03046 hypothetical protein; phosphoenolpyruvate-protein phosphotransferase 4492108 6065356 EcolC_4068 Escherichia coli ATCC 8739 phosphoenolpyruvate-protein phosphotransferase YP_001726994.1 4489607 D 481805 CDS YP_001726995.1 170022041 6065368 4492120..4492782 1 NC_010468.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4492782 6065368 EcolC_4069 Escherichia coli ATCC 8739 fructose-6-phosphate aldolase YP_001726995.1 4492120 D 481805 CDS YP_001726996.1 170022042 6065380 4492793..4493896 1 NC_010468.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4493896 gldA 6065380 gldA Escherichia coli ATCC 8739 glycerol dehydrogenase YP_001726996.1 4492793 D 481805 CDS YP_001726997.1 170022043 6065396 4494171..4494788 1 NC_010468.1 PFAM: protein of unknown function DUF1287; KEGG: sbo:SBO_3964 hypothetical protein; hypothetical protein 4494788 6065396 EcolC_4071 Escherichia coli ATCC 8739 hypothetical protein YP_001726997.1 4494171 D 481805 CDS YP_001726998.1 170022044 6065415 complement(4494815..4495720) 1 NC_010468.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4117 hypothetical protein; hypothetical protein 4495720 6065415 EcolC_4072 Escherichia coli ATCC 8739 hypothetical protein YP_001726998.1 4494815 R 481805 CDS YP_001726999.1 170022045 6065444 complement(4495813..4497993) 1 NC_010468.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: sfv:SFV_4012 catalase; hydroperoxidase HPI(I); catalase/peroxidase HPI 4497993 6065444 EcolC_4073 Escherichia coli ATCC 8739 catalase/peroxidase HPI YP_001726999.1 4495813 R 481805 CDS YP_001727000.1 170022046 6065481 complement(4498322..4499212) 1 NC_010468.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4499212 metF 6065481 metF Escherichia coli ATCC 8739 5,10-methylenetetrahydrofolate reductase YP_001727000.1 4498322 R 481805 CDS YP_001727001.1 170022047 6065484 complement(4499561..4501993) 1 NC_010468.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4501993 metL 6065484 metL Escherichia coli ATCC 8739 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_001727001.1 4499561 R 481805 CDS YP_001727002.1 170022048 6065486 complement(4501996..4503156) 1 NC_010468.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4503156 6065486 EcolC_4076 Escherichia coli ATCC 8739 cystathionine gamma-synthase YP_001727002.1 4501996 R 481805 CDS YP_001727003.1 170022049 6065518 4503433..4503750 1 NC_010468.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4503750 6065518 EcolC_4077 Escherichia coli ATCC 8739 transcriptional repressor protein MetJ YP_001727003.1 4503433 D 481805 CDS YP_001727004.1 170022050 6065575 4503934..4504542 1 NC_010468.1 member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase 4504542 6065575 EcolC_4078 Escherichia coli ATCC 8739 putative peptidoglycan peptidase YP_001727004.1 4503934 D 481805 CDS YP_001727005.1 170022051 6065594 4504687..4504959 1 NC_010468.1 PFAM: Insertion element protein; KEGG: sdy:SDY_P028 iso-IS1 ORF1; insertion element protein 4504959 6065594 EcolC_4079 Escherichia coli ATCC 8739 insertion element protein YP_001727005.1 4504687 D 481805 CDS YP_001727006.1 170022052 6065604 complement(4505774..4507915) 1 NC_010468.1 TIGRFAM: YD repeat protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein 4507915 6065604 EcolC_4081 Escherichia coli ATCC 8739 YD repeat-containing protein YP_001727006.1 4505774 R 481805 CDS YP_001727007.1 170022053 6065605 complement(4508075..4508287) 1 NC_010468.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4508287 rpmE 6065605 rpmE Escherichia coli ATCC 8739 50S ribosomal protein L31 YP_001727007.1 4508075 R 481805 CDS YP_001727008.1 170022054 6065614 4508490..4510688 1 NC_010468.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4510688 6065614 EcolC_4083 Escherichia coli ATCC 8739 primosome assembly protein PriA YP_001727008.1 4508490 D 481805 CDS YP_001727009.1 170022055 6065630 4510844..4511869 1 NC_010468.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4511869 6065630 EcolC_4084 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator CytR YP_001727009.1 4510844 D 481805 CDS YP_001727010.1 170022056 6065631 4512066..4512920 1 NC_010468.1 TIGRFAM: cell division protein FtsN; PFAM: Sporulation domain protein; KEGG: sbo:SBO_3950 essential cell division protein; cell division protein FtsN 4512920 6065631 EcolC_4085 Escherichia coli ATCC 8739 cell division protein FtsN YP_001727010.1 4512066 D 481805 CDS YP_001727011.1 170022057 6065638 4513013..4513543 1 NC_010468.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4513543 6065638 EcolC_4086 Escherichia coli ATCC 8739 ATP-dependent protease peptidase subunit YP_001727011.1 4513013 D 481805 CDS YP_001727012.1 170022058 6065640 4513553..4514884 1 NC_010468.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4514884 hslU 6065640 hslU Escherichia coli ATCC 8739 ATP-dependent protease ATP-binding subunit HslU YP_001727012.1 4513553 D 481805 CDS YP_001727013.1 170022059 6065651 4514951..4515877 1 NC_010468.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4515877 6065651 EcolC_4088 Escherichia coli ATCC 8739 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001727013.1 4514951 D 481805 CDS YP_001727014.1 170022060 6065657 4515970..4516455 1 NC_010468.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4516455 6065657 EcolC_4089 Escherichia coli ATCC 8739 ribonuclease activity regulator protein RraA YP_001727014.1 4515970 D 481805 CDS YP_001727015.1 170022061 6065674 complement(4516540..4516779) 1 NC_010468.1 PFAM: protein of unknown function DUF904; KEGG: sdy:SDY_3816 hypothetical protein; hypothetical protein 4516779 6065674 EcolC_4090 Escherichia coli ATCC 8739 hypothetical protein YP_001727015.1 4516540 R 481805 CDS YP_001727016.1 170022062 6065676 4517210..4518055 1 NC_010468.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: ssn:SSON_4096 facilitated diffusion of glycerol; MIP family channel protein 4518055 6065676 EcolC_4091 Escherichia coli ATCC 8739 MIP family channel protein YP_001727016.1 4517210 D 481805 CDS YP_001727017.1 170022063 6065683 4518078..4519586 1 NC_010468.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4519586 glpK 6065683 glpK Escherichia coli ATCC 8739 glycerol kinase YP_001727017.1 4518078 D 481805 CDS YP_001727018.1 170022064 6065689 4519592..4520731 1 NC_010468.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4520731 glpX 6065689 glpX Escherichia coli ATCC 8739 fructose 1,6-bisphosphatase II YP_001727018.1 4519592 D 481805 CDS YP_001727019.1 170022065 6065702 4520828..4521574 1 NC_010468.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sdy:SDY_3820 ferredoxin-NADP reductase; ferredoxin-NADP reductase 4521574 6065702 EcolC_4094 Escherichia coli ATCC 8739 ferredoxin-NADP reductase YP_001727019.1 4520828 D 481805 CDS YP_001727020.1 170022066 6065704 complement(4521579..4522007) 1 NC_010468.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4522007 6065704 EcolC_4095 Escherichia coli ATCC 8739 universal stress protein UspD YP_001727020.1 4521579 R 481805 CDS YP_001727021.1 170022067 6065705 complement(4522034..4522333) 1 NC_010468.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_4091 hypothetical protein; hypothetical protein 4522333 6065705 EcolC_4096 Escherichia coli ATCC 8739 hypothetical protein YP_001727021.1 4522034 R 481805 CDS YP_001727022.1 170022068 6065706 complement(4522545..4522985) 1 NC_010468.1 PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_4090 hypothetical protein; hypothetical protein 4522985 6065706 EcolC_4097 Escherichia coli ATCC 8739 hypothetical protein YP_001727022.1 4522545 R 481805 CDS YP_001727023.1 170022069 6065717 4523086..4523685 1 NC_010468.1 PFAM: protein of unknown function DUF1454; KEGG: sbo:SBO_3937 hypothetical protein; hypothetical protein 4523685 6065717 EcolC_4098 Escherichia coli ATCC 8739 hypothetical protein YP_001727023.1 4523086 D 481805 CDS YP_001727024.1 170022070 6065754 4523793..4524560 1 NC_010468.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4524560 tpiA 6065754 tpiA Escherichia coli ATCC 8739 triosephosphate isomerase YP_001727024.1 4523793 D 481805 CDS YP_001727025.1 170022071 6065760 complement(4524615..4525370) 1 NC_010468.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: sbo:SBO_3935 CDP-diacylglycerol phosphotidylhydrolase; CDP-diacylglycerol pyrophosphatase 4525370 6065760 EcolC_4100 Escherichia coli ATCC 8739 CDP-diacylglycerol pyrophosphatase YP_001727025.1 4524615 R 481805 CDS YP_001727026.1 170022072 6065790 complement(4525477..4526466) 1 NC_010468.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_4086 periplasmic sulfate-binding protein; sulfate transporter subunit 4526466 6065790 EcolC_4101 Escherichia coli ATCC 8739 sulfate transporter subunit YP_001727026.1 4525477 R 481805 CDS YP_001727027.1 170022073 6065796 complement(4526786..4527748) 1 NC_010468.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4527748 6065796 EcolC_4102 Escherichia coli ATCC 8739 6-phosphofructokinase YP_001727027.1 4526786 R 481805 CDS YP_001727028.1 170022074 6065858 complement(4527929..4528831) 1 NC_010468.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4528831 fieF 6065858 fieF Escherichia coli ATCC 8739 ferrous iron efflux protein F YP_001727028.1 4527929 R 481805 CDS YP_001727029.1 170022075 6065865 complement(4528980..4529480) 1 NC_010468.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4529480 cpxP 6065865 cpxP Escherichia coli ATCC 8739 repressor CpxP YP_001727029.1 4528980 R 481805 CDS YP_001727030.1 170022076 6065866 4529630..4530328 1 NC_010468.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4530328 6065866 EcolC_4105 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator CpxR YP_001727030.1 4529630 D 481805 CDS YP_001727031.1 170022077 6065886 4530325..4531698 1 NC_010468.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4531698 cpxA 6065886 cpxA Escherichia coli ATCC 8739 two-component sensor protein YP_001727031.1 4530325 D 481805 CDS YP_001727032.1 170022078 6065900 complement(4531804..4532478) 1 NC_010468.1 PFAM: 3-alpha domain protein; MOSC domain containing protein; KEGG: sbo:SBO_3928 hypothetical protein; hypothetical protein 4532478 6065900 EcolC_4107 Escherichia coli ATCC 8739 hypothetical protein YP_001727032.1 4531804 R 481805 CDS YP_001727033.1 170022079 6065901 complement(4532627..4533610) 1 NC_010468.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4533610 6065901 EcolC_4108 Escherichia coli ATCC 8739 2-keto-3-deoxygluconate permease YP_001727033.1 4532627 R 481805 CDS YP_001727034.1 170022080 6065910 complement(4533870..4534490) 1 NC_010468.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4534490 6065910 EcolC_4109 Escherichia coli ATCC 8739 superoxide dismutase YP_001727034.1 4533870 R 481805 CDS YP_001727035.1 170022081 6065918 4534775..4535809 1 NC_010468.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4535809 6065918 EcolC_4110 Escherichia coli ATCC 8739 rhamnose-proton symporter YP_001727035.1 4534775 D 481805 CDS YP_001727036.1 170022082 6065919 complement(4535806..4536744) 1 NC_010468.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4536744 6065919 EcolC_4111 Escherichia coli ATCC 8739 transcriptional activator RhaR YP_001727036.1 4535806 R 481805 CDS YP_001727037.1 170022083 6065922 complement(4536728..4537564) 1 NC_010468.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4537564 6065922 EcolC_4112 Escherichia coli ATCC 8739 transcriptional activator RhaS YP_001727037.1 4536728 R 481805 CDS YP_001727038.1 170022084 6065939 4537852..4539321 1 NC_010468.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4539321 rhaB 6065939 rhaB Escherichia coli ATCC 8739 rhamnulokinase YP_001727038.1 4537852 D 481805 CDS YP_001727039.1 170022085 6065949 4539318..4540577 1 NC_010468.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4540577 6065949 EcolC_4114 Escherichia coli ATCC 8739 L-rhamnose isomerase YP_001727039.1 4539318 D 481805 CDS YP_001727040.1 170022086 6065976 4541028..4541852 1 NC_010468.1 KEGG: ssn:SSON_4072 rhamnulose-phosphate aldolase; TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; rhamnulose-1-phosphate aldolase 4541852 6065976 EcolC_4115 Escherichia coli ATCC 8739 rhamnulose-1-phosphate aldolase YP_001727040.1 4541028 D 481805 CDS YP_001727041.1 170022087 6065994 4541862..4542176 1 NC_010468.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: sfv:SFV_3594 hypothetical protein; L-rhamnose 1-epimerase 4542176 6065994 EcolC_4116 Escherichia coli ATCC 8739 L-rhamnose 1-epimerase YP_001727041.1 4541862 D 481805 CDS YP_001727042.1 170022088 6065995 4542477..4542923 1 NC_010468.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; putative PTS system fructose-specific transporter subunit IIA 4542923 6065995 EcolC_4117 Escherichia coli ATCC 8739 putative PTS system fructose-specific transporter subunit IIA YP_001727042.1 4542477 D 481805 CDS YP_001727043.1 170022089 6065997 4542934..4544385 1 NC_010468.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS fructose-specific IIB subunit; KEGG: sbo:SBO_3915 PTS system fructose-like enzyme IIBC component; putative PTS system transporter subunits IIBC 4544385 6065997 EcolC_4118 Escherichia coli ATCC 8739 putative PTS system transporter subunits IIBC YP_001727043.1 4542934 D 481805 CDS YP_001727044.1 170022090 6066001 4544375..4545445 1 NC_010468.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; putative fructose-specific phosphotransferase system protein FrvX 4545445 6066001 EcolC_4119 Escherichia coli ATCC 8739 putative fructose-specific phosphotransferase system protein FrvX YP_001727044.1 4544375 D 481805 CDS YP_001727045.1 170022091 6066004 4545445..4547193 1 NC_010468.1 putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; putative frv operon regulatory protein 4547193 6066004 EcolC_4120 Escherichia coli ATCC 8739 putative frv operon regulatory protein YP_001727045.1 4545445 D 481805 CDS YP_001727046.1 170022092 6066025 complement(4547243..4548298) 1 NC_010468.1 KEGG: sbo:SBO_3910 hypothetical protein; hypothetical protein 4548298 6066025 EcolC_4121 Escherichia coli ATCC 8739 hypothetical protein YP_001727046.1 4547243 R 481805 CDS YP_001727047.1 170022093 6066033 complement(4548451..4549284) 1 NC_010468.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4549284 6066033 EcolC_4122 Escherichia coli ATCC 8739 formate dehydrogenase accessory protein YP_001727047.1 4548451 R 481805 CDS YP_001727048.1 170022094 6066049 4549478..4552528 1 NC_010468.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sbo:SBO_3908 formate dehydrogenase-O, major subunit; KEGG: ssn:SSON_4063 formate dehydrogenase-O, major subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase subunit alpha 4552528 6066049 EcolC_4123 Escherichia coli ATCC 8739 molybdopterin oxidoreductase subunit alpha YP_001727048.1 4549478 D 481805 CDS YP_001727049.1 170022095 6066050 4552541..4553443 1 NC_010468.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbo:SBO_3907 formate dehydrogenase-O, iron-sulfur subunit; formate dehydrogenase subunit beta 4553443 6066050 EcolC_4125 Escherichia coli ATCC 8739 formate dehydrogenase subunit beta YP_001727049.1 4552541 D 481805 CDS YP_001727050.1 170022096 6066059 4553440..4554075 1 NC_010468.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4554075 6066059 EcolC_4126 Escherichia coli ATCC 8739 formate dehydrogenase-O subunit gamma YP_001727050.1 4553440 D 481805 CDS YP_001727051.1 170022097 6066100 4554072..4555001 1 NC_010468.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4555001 6066100 EcolC_4127 Escherichia coli ATCC 8739 formate dehydrogenase accessory protein FdhE YP_001727051.1 4554072 D 481805 CDS YP_001727052.1 170022098 6066121 complement(4555331..4555573) 1 NC_010468.1 KEGG: sbo:SBO_3904 hypothetical protein; hypothetical protein 4555573 6066121 EcolC_4128 Escherichia coli ATCC 8739 hypothetical protein YP_001727052.1 4555331 R 481805 CDS YP_001727053.1 170022099 6066174 complement(4555791..4556009) 1 NC_010468.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sfv:SFV_3606 hypothetical protein; CopG family transcriptional regulator 4556009 6066174 EcolC_4129 Escherichia coli ATCC 8739 CopG family transcriptional regulator YP_001727053.1 4555791 R 481805 CDS YP_001727054.1 170022100 6066193 complement(4556861..4557802) 1 NC_010468.1 TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; Thioesterase putative; KEGG: sbo:SBO_3902 putative acetyltransferase; thioesterase domain-containing protein 4557802 6066193 EcolC_4130 Escherichia coli ATCC 8739 thioesterase domain-containing protein YP_001727054.1 4556861 R 481805 CDS YP_001727055.1 170022101 6066199 complement(4557847..4558284) 1 NC_010468.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4558284 6066199 EcolC_4131 Escherichia coli ATCC 8739 D-tyrosyl-tRNA(Tyr) deacylase YP_001727055.1 4557847 R 481805 CDS YP_001727056.1 170022102 6066201 complement(4558281..4559153) 1 NC_010468.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4559153 rbn 6066201 rbn Escherichia coli ATCC 8739 ribonuclease BN YP_001727056.1 4558281 R 481805 CDS YP_001727057.1 170022103 6066216 complement(4559147..4559746) 1 NC_010468.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ssn:SSON_4054 putative phosphatase; phosphatase 4559746 6066216 EcolC_4133 Escherichia coli ATCC 8739 phosphatase YP_001727057.1 4559147 R 481805 CDS YP_001727058.1 170022104 6066225 complement(4559887..4560774) 1 NC_010468.1 PFAM: Aldose 1-epimerase; KEGG: sbo:SBO_3898 hypothetical protein; aldose 1-epimerase 4560774 6066225 EcolC_4134 Escherichia coli ATCC 8739 aldose 1-epimerase YP_001727058.1 4559887 R 481805 CDS YP_001727059.1 170022105 6066227 complement(4560764..4562113) 1 NC_010468.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4052 putative transport protein shikimate; general substrate transporter 4562113 6066227 EcolC_4135 Escherichia coli ATCC 8739 general substrate transporter YP_001727059.1 4560764 R 481805 CDS YP_001727060.1 170022106 6066230 complement(4562212..4563645) 1 NC_010468.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4051 putative transporter; major facilitator transporter 4563645 6066230 EcolC_4136 Escherichia coli ATCC 8739 major facilitator transporter YP_001727060.1 4562212 R 481805 CDS YP_001727061.1 170022107 6066242 complement(4563715..4564725) 1 NC_010468.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_4050 putative dehydrogenase; alcohol dehydrogenase 4564725 6066242 EcolC_4137 Escherichia coli ATCC 8739 alcohol dehydrogenase YP_001727061.1 4563715 R 481805 CDS YP_001727062.1 170022108 6066243 complement(4564758..4565645) 1 NC_010468.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ssn:SSON_4049 putative aldolase; deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase 4565645 6066243 EcolC_4138 Escherichia coli ATCC 8739 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase YP_001727062.1 4564758 R 481805 CDS YP_001727063.1 170022109 6066245 complement(4565670..4566548) 1 NC_010468.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ssn:SSON_4048 putative dehydrogenase; 3-hydroxyisobutyrate dehydrogenase 4566548 6066245 EcolC_4139 Escherichia coli ATCC 8739 3-hydroxyisobutyrate dehydrogenase YP_001727063.1 4565670 R 481805 CDS YP_001727064.1 170022110 6066259 4566721..4567617 1 NC_010468.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_3886 putative kinase; ribokinase-like domain-containing protein 4567617 6066259 EcolC_4140 Escherichia coli ATCC 8739 ribokinase-like domain-containing protein YP_001727064.1 4566721 D 481805 CDS YP_001727065.1 170022111 6066268 4567657..4568445 1 NC_010468.1 PFAM: regulatory protein GntR HTH; regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: ssn:SSON_4045 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 4568445 6066268 EcolC_4141 Escherichia coli ATCC 8739 DeoR family transcriptional regulator YP_001727065.1 4567657 D 481805 CDS YP_001727066.1 170022112 6066287 complement(4568556..4569821) 1 NC_010468.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3626 putative resistance protein (transport); major facilitator transporter 4569821 6066287 EcolC_4142 Escherichia coli ATCC 8739 major facilitator transporter YP_001727066.1 4568556 R 481805 CDS YP_001727067.1 170022113 6066295 complement(4569923..4570903) 1 NC_010468.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sfx:S3803 hypothetical protein; xylose isomerase domain-containing protein 4570903 6066295 EcolC_4143 Escherichia coli ATCC 8739 xylose isomerase domain-containing protein YP_001727067.1 4569923 R 481805 CDS YP_001727068.1 170022114 6066302 complement(4570911..4571621) 1 NC_010468.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sfv:SFV_3628 putative transcriptional regulator; GntR family transcriptional regulator 4571621 6066302 EcolC_4144 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001727068.1 4570911 R 481805 CDS YP_001727069.1 170022115 6066308 complement(4571838..4573661) 1 NC_010468.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: sdy:SDY_3872 putative GTP-binding factor; GTP-binding protein 4573661 6066308 EcolC_4145 Escherichia coli ATCC 8739 GTP-binding protein YP_001727069.1 4571838 R 481805 CDS YP_001727070.1 170022116 6066327 4574034..4575443 1 NC_010468.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4575443 glnA 6066327 glnA Escherichia coli ATCC 8739 glutamine synthetase YP_001727070.1 4574034 D 481805 CDS YP_001727071.1 170022117 6066346 4575729..4576778 1 NC_010468.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4576778 glnL 6066346 glnL Escherichia coli ATCC 8739 nitrogen regulation protein NR(II) YP_001727071.1 4575729 D 481805 CDS YP_001727072.1 170022118 6066358 4576790..4578199 1 NC_010468.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4578199 glnG 6066358 glnG Escherichia coli ATCC 8739 nitrogen regulation protein NR(I) YP_001727072.1 4576790 D 481805 CDS YP_001727073.1 170022119 6066365 complement(4578611..4579984) 1 NC_010468.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4579984 6066365 EcolC_4149 Escherichia coli ATCC 8739 coproporphyrinogen III oxidase YP_001727073.1 4578611 R 481805 CDS YP_001727074.1 170022120 6066371 complement(4580173..4580679) 1 NC_010468.1 PFAM: protein of unknown function DUF414; KEGG: sdy:SDY_3877 hypothetical protein; hypothetical protein 4580679 6066371 EcolC_4150 Escherichia coli ATCC 8739 hypothetical protein YP_001727074.1 4580173 R 481805 CDS YP_001727075.1 170022121 6066397 4581261..4581893 1 NC_010468.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4581893 engB 6066397 engB Escherichia coli ATCC 8739 ribosome biogenesis GTP-binding protein YsxC YP_001727075.1 4581261 D 481805 CDS YP_001727076.1 170022122 6066521 complement(4582275..4585061) 1 NC_010468.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4585061 6066521 EcolC_4152 Escherichia coli ATCC 8739 DNA polymerase I YP_001727076.1 4582275 R 481805 CDS YP_001727077.1 170022123 6066543 4585425..4586357 1 NC_010468.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: ssn:SSON_4035 putative endonuclease; putative acyltransferase 4586357 6066543 EcolC_4153 Escherichia coli ATCC 8739 putative acyltransferase YP_001727077.1 4585425 D 481805 CDS YP_001727078.1 170022124 6066576 complement(4586398..4587828) 1 NC_010468.1 PFAM: protein of unknown function DUF945; KEGG: sfx:S3815 putative GTP-binding protein; hypothetical protein 4587828 6066576 EcolC_4154 Escherichia coli ATCC 8739 hypothetical protein YP_001727078.1 4586398 R 481805 CDS YP_001727079.1 170022125 6066594 complement(4587983..4588609) 1 NC_010468.1 PFAM: DSBA oxidoreductase; KEGG: sbo:SBO_3872 protein disulfide isomerase I; protein disulfide isomerase I 4588609 6066594 EcolC_4155 Escherichia coli ATCC 8739 protein disulfide isomerase I YP_001727079.1 4587983 R 481805 CDS YP_001727080.1 170022126 6066606 complement(4588626..4589612) 1 NC_010468.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4589612 6066606 EcolC_4156 Escherichia coli ATCC 8739 serine/threonine protein kinase YP_001727080.1 4588626 R 481805 CDS YP_001727081.1 170022127 6066668 complement(4589689..4589958) 1 NC_010468.1 PFAM: protein of unknown function DUF1040; KEGG: sdy:SDY_3887 hypothetical protein; hypothetical protein 4589958 6066668 EcolC_4157 Escherichia coli ATCC 8739 hypothetical protein YP_001727081.1 4589689 R 481805 CDS YP_001727082.1 170022128 6066689 4590028..4590612 1 NC_010468.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4590612 mobA 6066689 mobA Escherichia coli ATCC 8739 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_001727082.1 4590028 D 481805 CDS YP_001727083.1 170022129 6066708 4590594..4591121 1 NC_010468.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4591121 6066708 EcolC_4159 Escherichia coli ATCC 8739 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001727083.1 4590594 D 481805 CDS YP_001727084.1 170022130 6066981 complement(4596703..4597248) 1 NC_010468.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4597248 hemG 6066981 hemG Escherichia coli ATCC 8739 protoporphyrinogen oxidase YP_001727084.1 4596703 R 481805 CDS YP_001727085.1 170022131 6067037 complement(4597260..4598711) 1 NC_010468.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: sdy:SDY_3896 potassium uptake protein; potassium transporter 4598711 6067037 EcolC_4161 Escherichia coli ATCC 8739 potassium transporter YP_001727085.1 4597260 R 481805 CDS YP_001727086.1 170022132 6067045 complement(4598750..4599367) 1 NC_010468.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: sdy:SDY_3897 hypothetical protein; hypothetical protein 4599367 6067045 EcolC_4162 Escherichia coli ATCC 8739 hypothetical protein YP_001727086.1 4598750 R 481805 CDS YP_001727087.1 170022133 6067067 complement(4599364..4600695) 1 NC_010468.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4600695 6067067 EcolC_4163 Escherichia coli ATCC 8739 proline dipeptidase YP_001727087.1 4599364 R 481805 CDS YP_001727088.1 170022134 6067071 4600885..4603074 1 NC_010468.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4603074 fadB 6067071 fadB Escherichia coli ATCC 8739 multifunctional fatty acid oxidation complex subunit alpha YP_001727088.1 4600885 D 481805 CDS YP_001727089.1 170022135 6067123 4603084..4604247 1 NC_010468.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4604247 fadA 6067123 fadA Escherichia coli ATCC 8739 3-ketoacyl-CoA thiolase YP_001727089.1 4603084 D 481805 CDS YP_001727090.1 170022136 6067132 complement(4604431..4605132) 1 NC_010468.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4605132 fre 6067132 fre Escherichia coli ATCC 8739 FMN reductase YP_001727090.1 4604431 R 481805 CDS YP_001727091.1 170022137 6067168 complement(4605178..4606671) 1 NC_010468.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4606671 6067168 EcolC_4167 Escherichia coli ATCC 8739 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001727091.1 4605178 R 481805 CDS YP_001727092.1 170022138 6067170 4606838..4607326 1 NC_010468.1 TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; KEGG: sdy:SDY_3903 transcriptional activator affecting biosynthesis of lipopolysaccharide core, F pilin, and haemolysin; transcriptional activator RfaH 4607326 rfaH 6067170 rfaH Escherichia coli ATCC 8739 transcriptional activator RfaH YP_001727092.1 4606838 D 481805 CDS YP_001727093.1 170022139 6067207 complement(4607323..4608105) 1 NC_010468.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4608105 6067207 EcolC_4169 Escherichia coli ATCC 8739 DNase TatD YP_001727093.1 4607323 R 481805 CDS YP_001727094.1 170022140 6067234 complement(4608147..4608923) 1 NC_010468.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4608923 6067234 EcolC_4170 Escherichia coli ATCC 8739 twin-arginine protein translocation system subunit TatC YP_001727094.1 4608147 R 481805 CDS YP_001727095.1 170022141 6067245 complement(4608926..4609441) 1 NC_010468.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4609441 6067245 EcolC_4171 Escherichia coli ATCC 8739 sec-independent translocase YP_001727095.1 4608926 R 481805 CDS YP_001727096.1 170022142 6067249 complement(4609445..4609714) 1 NC_010468.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4609714 tatA 6067249 tatA Escherichia coli ATCC 8739 twin arginine translocase protein A YP_001727096.1 4609445 R 481805 CDS YP_001727097.1 170022143 6067256 complement(4609793..4611433) 1 NC_010468.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 4611433 ubiB 6067256 ubiB Escherichia coli ATCC 8739 putative ubiquinone biosynthesis protein UbiB YP_001727097.1 4609793 R 481805 CDS YP_001727098.1 170022144 6067258 complement(4611430..4612035) 1 NC_010468.1 PFAM: Sterol-binding domain protein; KEGG: sbo:SBO_3848 hypothetical protein; sterol-binding domain-containing protein 4612035 6067258 EcolC_4174 Escherichia coli ATCC 8739 sterol-binding domain-containing protein YP_001727098.1 4611430 R 481805 CDS YP_001727099.1 170022145 6067259 complement(4612049..4612804) 1 NC_010468.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4612804 ubiE 6067259 ubiE Escherichia coli ATCC 8739 ubiquinone/menaquinone biosynthesis methyltransferase YP_001727099.1 4612049 R 481805 CDS YP_001727100.1 170022146 6067265 complement(4612899..4614326) 1 NC_010468.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4614326 6067265 EcolC_4176 Escherichia coli ATCC 8739 DNA recombination protein RmuC YP_001727100.1 4612899 R 481805 CDS YP_001727101.1 170022147 6067267 complement(4614467..4615228) 1 NC_010468.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4615228 6067267 EcolC_4177 Escherichia coli ATCC 8739 uridine phosphorylase YP_001727101.1 4614467 R 481805 CDS YP_001727102.1 170022148 6067276 4615491..4616306 1 NC_010468.1 PFAM: dienelactone hydrolase; KEGG: sfl:SF3908 carboxymethylenebutenolidase; carboxymethylenebutenolidase 4616306 6067276 EcolC_4178 Escherichia coli ATCC 8739 carboxymethylenebutenolidase YP_001727102.1 4615491 D 481805 CDS YP_001727103.1 170022149 6067326 complement(4616346..4618607) 1 NC_010468.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4618607 6067326 EcolC_4179 Escherichia coli ATCC 8739 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001727103.1 4616346 R 481805 CDS YP_001727104.1 170022150 6067345 4618725..4619678 1 NC_010468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3840 MetR; LysR family transcriptional regulator 4619678 6067345 EcolC_4180 Escherichia coli ATCC 8739 LysR family transcriptional regulator YP_001727104.1 4618725 D 481805 CDS YP_001727105.1 170022151 6067347 complement(4619566..4620465) 1 NC_010468.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4001 hypothetical protein; carboxylate/amino acid/amine transporter 4620465 6067347 EcolC_4181 Escherichia coli ATCC 8739 carboxylate/amino acid/amine transporter YP_001727105.1 4619566 R 481805 CDS YP_001727106.1 170022152 6067364 complement(4620541..4621341) 1 NC_010468.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 4621341 6067364 EcolC_4182 Escherichia coli ATCC 8739 putative sugar phosphatase YP_001727106.1 4620541 R 481805 CDS YP_001727107.1 170022153 6067418 complement(4621349..4622371) 1 NC_010468.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4622371 6067418 EcolC_4183 Escherichia coli ATCC 8739 lysophospholipase L2 YP_001727107.1 4621349 R 481805 CDS YP_001727108.1 170022154 6067426 4622482..4623102 1 NC_010468.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3674 hypothetical protein; homoserine/homoserine lactone efflux protein 4623102 rhtB 6067426 rhtB Escherichia coli ATCC 8739 homoserine/homoserine lactone efflux protein YP_001727108.1 4622482 D 481805 CDS YP_001727109.1 170022155 6067430 complement(4623164..4623784) 1 NC_010468.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3675 hypothetical protein; threonine efflux system 4623784 6067430 EcolC_4185 Escherichia coli ATCC 8739 threonine efflux system YP_001727109.1 4623164 R 481805 CDS YP_001727110.1 170022156 6067433 complement(4623848..4625677) 1 NC_010468.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4625677 6067433 EcolC_4186 Escherichia coli ATCC 8739 ATP-dependent DNA helicase RecQ YP_001727110.1 4623848 R 481805 CDS YP_001727111.1 170022157 6067449 complement(4625810..4626679) 1 NC_010468.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4626679 6067449 EcolC_4187 Escherichia coli ATCC 8739 phospholipase A YP_001727111.1 4625810 R 481805 CDS YP_001727112.1 170022158 6067456 4626844..4627311 1 NC_010468.1 PFAM: thioesterase superfamily protein; KEGG: ssn:SSON_3994 hypothetical protein; hypothetical protein 4627311 6067456 EcolC_4188 Escherichia coli ATCC 8739 hypothetical protein YP_001727112.1 4626844 D 481805 CDS YP_001727113.1 170022159 6067462 4627363..4628253 1 NC_010468.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfv:SFV_3679 hypothetical protein; transporter DMT superfamily protein 4628253 6067462 EcolC_4189 Escherichia coli ATCC 8739 transporter DMT superfamily protein YP_001727113.1 4627363 D 481805 CDS YP_001727114.1 170022160 6067479 4628348..4628728 1 NC_010468.1 KEGG: sfx:S3859 hypothetical protein; hypothetical protein 4628728 6067479 EcolC_4190 Escherichia coli ATCC 8739 hypothetical protein YP_001727114.1 4628348 D 481805 CDS YP_001727115.1 170022161 6067502 4628742..4629122 1 NC_010468.1 KEGG: sfv:SFV_3681 hypothetical protein; hypothetical protein 4629122 6067502 EcolC_4191 Escherichia coli ATCC 8739 hypothetical protein YP_001727115.1 4628742 D 481805 CDS YP_001727116.1 170022162 6067503 complement(4629165..4630115) 1 NC_010468.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4630115 6067503 EcolC_4192 Escherichia coli ATCC 8739 magnesium/nickel/cobalt transporter CorA YP_001727116.1 4629165 R 481805 CDS YP_001727117.1 170022163 6067513 4630485..4631249 1 NC_010468.1 KEGG: sdy:SDY_3930 predicted periplasmic protein; hypothetical protein 4631249 6067513 EcolC_4193 Escherichia coli ATCC 8739 hypothetical protein YP_001727117.1 4630485 D 481805 CDS YP_001727118.1 170022164 6067516 complement(4631396..4633558) 1 NC_010468.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4633558 uvrD 6067516 uvrD Escherichia coli ATCC 8739 DNA-dependent helicase II YP_001727118.1 4631396 R 481805 CDS YP_001727119.1 170022165 6067538 complement(4633642..4634358) 1 NC_010468.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4634358 6067538 EcolC_4195 Escherichia coli ATCC 8739 flavin mononucleotide phosphatase YP_001727119.1 4633642 R 481805 CDS YP_001727120.1 170022166 6067551 complement(4634358..4635254) 1 NC_010468.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4635254 xerC 6067551 xerC Escherichia coli ATCC 8739 site-specific tyrosine recombinase XerC YP_001727120.1 4634358 R 481805 CDS YP_001727121.1 170022167 6067552 complement(4635251..4635958) 1 NC_010468.1 PFAM: protein of unknown function DUF484; KEGG: sbo:SBO_3821 hypothetical protein; hypothetical protein 4635958 6067552 EcolC_4197 Escherichia coli ATCC 8739 hypothetical protein YP_001727121.1 4635251 R 481805 CDS YP_001727122.1 170022168 6067553 complement(4635955..4636779) 1 NC_010468.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4636779 dapF 6067553 dapF Escherichia coli ATCC 8739 diaminopimelate epimerase YP_001727122.1 4635955 R 481805 CDS YP_001727123.1 170022169 6067578 complement(4636816..4637019) 1 NC_010468.1 KEGG: ssn:SSON_3981 hypothetical protein; hypothetical protein 4637019 6067578 EcolC_4199 Escherichia coli ATCC 8739 hypothetical protein YP_001727123.1 4636816 R 481805 CDS YP_001727124.1 170022170 6067589 4637482..4637802 1 NC_010468.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4637802 cyaY 6067589 cyaY Escherichia coli ATCC 8739 frataxin-like protein YP_001727124.1 4637482 D 481805 CDS YP_001727125.1 170022171 6067657 complement(4637842..4640388) 1 NC_010468.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4640388 cyaA 6067657 cyaA Escherichia coli ATCC 8739 adenylate cyclase YP_001727125.1 4637842 R 481805 CDS YP_001727126.1 170022172 6067671 4640754..4641716 1 NC_010468.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4641716 hemC 6067671 hemC Escherichia coli ATCC 8739 porphobilinogen deaminase YP_001727126.1 4640754 D 481805 CDS YP_001727127.1 170022173 6067687 4641713..4642453 1 NC_010468.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4642453 hemD 6067687 hemD Escherichia coli ATCC 8739 uroporphyrinogen-III synthase YP_001727127.1 4641713 D 481805 CDS YP_001727128.1 170022174 6067694 4642475..4643668 1 NC_010468.1 PFAM: protein of unknown function DUF513 hemX; KEGG: sfx:S3881 uroporphyrinogen III methylase; putative uroporphyrinogen III C-methyltransferase 4643668 6067694 EcolC_4204 Escherichia coli ATCC 8739 putative uroporphyrinogen III C-methyltransferase YP_001727128.1 4642475 D 481805 CDS YP_001727129.1 170022175 6067700 4643671..4644867 1 NC_010468.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: sbo:SBO_3813 HemY; putative protoheme IX biogenesis protein 4644867 6067700 EcolC_4205 Escherichia coli ATCC 8739 putative protoheme IX biogenesis protein YP_001727129.1 4643671 D 481805 CDS YP_001727130.1 170022176 6067713 complement(4645791..4647026) 1 NC_010468.1 PFAM: Radical SAM domain protein; KEGG: sfv:SFV_3703 putative arylsulfatase regulator; radical SAM domain-containing protein 4647026 6067713 EcolC_4206 Escherichia coli ATCC 8739 radical SAM domain-containing protein YP_001727130.1 4645791 R 481805 CDS YP_001727131.1 170022177 6067731 complement(4647712..4649097) 1 NC_010468.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 4649097 6067731 EcolC_4207 Escherichia coli ATCC 8739 putative transport protein YifK YP_001727131.1 4647712 R 481805 CDS YP_001727132.1 170022178 6067745 complement(4649288..4650028) 1 NC_010468.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: sdy:SDY_3953 probable UDP-N-acetyl-D-mannosaminuronic acid transferase; putative UDP-N-acetyl-D-mannosaminuronic acid transferase 4650028 6067745 EcolC_4208 Escherichia coli ATCC 8739 putative UDP-N-acetyl-D-mannosaminuronic acid transferase YP_001727132.1 4649288 R 481805 CDS YP_001727133.1 170022179 6067749 complement(4650031..4651383) 1 NC_010468.1 enterobacterial common antigen polymerase; putative common antigen polymerase 4651383 6067749 EcolC_4209 Escherichia coli ATCC 8739 putative common antigen polymerase YP_001727133.1 4650031 R 481805 CDS YP_001727134.1 170022180 6067755 complement(4651380..4652459) 1 NC_010468.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4652459 6067755 EcolC_4210 Escherichia coli ATCC 8739 4-alpha-L-fucosyltransferase YP_001727134.1 4651380 R 481805 CDS YP_001727135.1 170022181 6067756 complement(4652456..4653706) 1 NC_010468.1 PFAM: polysaccharide biosynthesis protein; KEGG: sbo:SBO_3803 putative cytochrome; polysaccharide biosynthesis protein 4653706 6067756 EcolC_4211 Escherichia coli ATCC 8739 polysaccharide biosynthesis protein YP_001727135.1 4652456 R 481805 CDS YP_001727136.1 170022182 6067760 complement(4653708..4654838) 1 NC_010468.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4654838 6067760 EcolC_4212 Escherichia coli ATCC 8739 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_001727136.1 4653708 R 481805 CDS YP_001727137.1 170022183 6067774 complement(4654843..4655517) 1 NC_010468.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_3714 hypothetical protein; TDP-fucosamine acetyltransferase 4655517 6067774 EcolC_4213 Escherichia coli ATCC 8739 TDP-fucosamine acetyltransferase YP_001727137.1 4654843 R 481805 CDS YP_001727138.1 170022184 6067780 complement(4655495..4656376) 1 NC_010468.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfv:SFV_3715 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 4656376 6067780 EcolC_4214 Escherichia coli ATCC 8739 glucose-1-phosphate thymidylyltransferase YP_001727138.1 4655495 R 481805 CDS YP_001727139.1 170022185 6067781 complement(4656395..4657462) 1 NC_010468.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ssn:SSON_3960 dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 4657462 6067781 EcolC_4215 Escherichia coli ATCC 8739 dTDP-glucose 4,6-dehydratase YP_001727139.1 4656395 R 481805 CDS YP_001727140.1 170022186 6067782 complement(4657462..4658724) 1 NC_010468.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4658724 wecC 6067782 wecC Escherichia coli ATCC 8739 UDP-N-acetyl-D-mannosamine dehydrogenase YP_001727140.1 4657462 R 481805 CDS YP_001727141.1 170022187 6067787 complement(4658721..4659851) 1 NC_010468.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: sdy:SDY_3962 UDP-N-acetyl glucosamine -2-epimerase; UDP-N-acetylglucosamine 2-epimerase 4659851 6067787 EcolC_4217 Escherichia coli ATCC 8739 UDP-N-acetylglucosamine 2-epimerase YP_001727141.1 4658721 R 481805 CDS YP_001727142.1 170022188 6067792 complement(4659907..4660953) 1 NC_010468.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4660953 6067792 EcolC_4218 Escherichia coli ATCC 8739 lipopolysaccharide biosynthesis protein WzzE YP_001727142.1 4659907 R 481805 CDS YP_001727143.1 170022189 6067801 complement(4660965..4662068) 1 NC_010468.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: ssn:SSON_3956 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 4662068 6067801 EcolC_4219 Escherichia coli ATCC 8739 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001727143.1 4660965 R 481805 CDS YP_001727144.1 170022190 6067806 complement(4662308..4663567) 1 NC_010468.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4663567 rho 6067806 rho Escherichia coli ATCC 8739 transcription termination factor Rho YP_001727144.1 4662308 R 481805 CDS YP_001727145.1 170022191 6067807 complement(4663652..4663753) 1 NC_010468.1 KEGG: sdy:SDY_3967 rho operon leader peptide; putative rho operon leader peptide 4663753 6067807 EcolC_4221 Escherichia coli ATCC 8739 putative rho operon leader peptide YP_001727145.1 4663652 R 481805 CDS YP_001727146.1 170022192 6067813 complement(4663894..4664223) 1 NC_010468.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cko:CKO_00123 hypothetical protein; thioredoxin 4664223 trxA 6067813 trxA Escherichia coli ATCC 8739 thioredoxin YP_001727146.1 4663894 R 481805 CDS YP_001727147.1 170022193 6067816 4664354..4665619 1 NC_010468.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4665619 6067816 EcolC_4223 Escherichia coli ATCC 8739 ATP-dependent RNA helicase RhlB YP_001727147.1 4664354 D 481805 CDS YP_001727148.1 170022194 6067819 4665755..4667239 1 NC_010468.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4667239 6067819 EcolC_4224 Escherichia coli ATCC 8739 guanosine pentaphosphate phosphohydrolase YP_001727148.1 4665755 D 481805 CDS YP_001727149.1 170022195 6067822 complement(4667286..4669307) 1 NC_010468.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4669307 6067822 EcolC_4225 Escherichia coli ATCC 8739 ATP-dependent DNA helicase Rep YP_001727149.1 4667286 R 481805 CDS YP_001727150.1 170022196 6067828 4670171..4670452 1 NC_010468.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cko:CKO_00116 hypothetical protein; PpiC-type peptidyl-prolyl cis-trans isomerase 4670452 6067828 EcolC_4227 Escherichia coli ATCC 8739 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001727150.1 4670171 D 481805 CDS YP_001727151.1 170022197 6067837 complement(4670539..4672014) 1 NC_010468.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4672014 6067837 EcolC_4228 Escherichia coli ATCC 8739 ketol-acid reductoisomerase YP_001727151.1 4670539 R 481805 CDS YP_001727152.1 170022198 6067840 4672164..4673057 1 NC_010468.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4673057 6067840 EcolC_4229 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator IlvY YP_001727152.1 4672164 D 481805 CDS YP_001727153.1 170022199 6067843 complement(4673109..4674656) 1 NC_010468.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4674656 6067843 EcolC_4230 Escherichia coli ATCC 8739 threonine dehydratase YP_001727153.1 4673109 R 481805 CDS YP_001727154.1 170022200 6067855 complement(4674656..4676506) 1 NC_010468.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4676506 6067855 EcolC_4231 Escherichia coli ATCC 8739 dihydroxy-acid dehydratase YP_001727154.1 4674656 R 481805 CDS YP_001727155.1 170022201 6067857 complement(4676571..4677500) 1 NC_010468.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4677500 6067857 EcolC_4232 Escherichia coli ATCC 8739 branched-chain amino acid aminotransferase YP_001727155.1 4676571 R 481805 CDS YP_001727156.1 170022202 6067861 complement(4677520..4677783) 1 NC_010468.1 KEGG: sdy:SDY_3979 acetolactate synthase II, valine insensitive, small subunit; acetolactate synthase 2 regulatory subunit 4677783 ilvM 6067861 ilvM Escherichia coli ATCC 8739 acetolactate synthase 2 regulatory subunit YP_001727156.1 4677520 R 481805 CDS YP_001727157.1 170022203 6067862 complement(4677780..4679426) 1 NC_010468.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4679426 6067862 EcolC_4234 Escherichia coli ATCC 8739 acetolactate synthase 2 catalytic subunit YP_001727157.1 4677780 R 481805 CDS YP_001727158.1 170022204 6067864 complement(4679566..4679664) 1 NC_010468.1 PFAM: IlvGEDA operon leader peptide; KEGG: sdy:SDY_3981 ilvGMEDA operon leader peptide; ilvG operon leader peptide 4679664 6067864 EcolC_4235 Escherichia coli ATCC 8739 ilvG operon leader peptide YP_001727158.1 4679566 R 481805 CDS YP_001727159.1 170022205 6067869 4680017..4681537 1 NC_010468.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease 4681537 6067869 EcolC_4236 Escherichia coli ATCC 8739 putative ATP-dependent protease YP_001727159.1 4680017 D 481805 CDS YP_001727160.1 170022206 6067870 complement(4681562..4681900) 1 NC_010468.1 PFAM: protein of unknown function DUF413; KEGG: sdy:SDY_3984 hypothetical protein; hypothetical protein 4681900 6067870 EcolC_4237 Escherichia coli ATCC 8739 hypothetical protein YP_001727160.1 4681562 R 481805 CDS YP_001727161.1 170022207 6067872 4682019..4682858 1 NC_010468.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4682858 6067872 EcolC_4238 Escherichia coli ATCC 8739 transcriptional regulator HdfR YP_001727161.1 4682019 D 481805 CDS YP_001727162.1 170022208 6067916 4688661..4689353 1 NC_010468.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfv:SFV_3744 hypothetical protein; GntR family transcriptional regulator 4689353 6067916 EcolC_4239 Escherichia coli ATCC 8739 GntR family transcriptional regulator YP_001727162.1 4688661 D 481805 CDS YP_001727163.1 170022209 6067919 4689376..4690803 1 NC_010468.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_3993 putative transport protein; EmrB/QacA family drug resistance transporter 4690803 6067919 EcolC_4240 Escherichia coli ATCC 8739 EmrB/QacA family drug resistance transporter YP_001727163.1 4689376 D 481805 CDS YP_001727164.1 170022210 6067932 complement(4690769..4691761) 1 NC_010468.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4691761 6067932 EcolC_4241 Escherichia coli ATCC 8739 transcriptional repressor RbsR YP_001727164.1 4690769 R 481805 CDS YP_001727165.1 170022211 6067934 complement(4691765..4692694) 1 NC_010468.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4692694 6067934 EcolC_4242 Escherichia coli ATCC 8739 ribokinase YP_001727165.1 4691765 R 481805 CDS YP_001727166.1 170022212 6067935 complement(4692820..4693710) 1 NC_010468.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4693710 6067935 EcolC_4243 Escherichia coli ATCC 8739 D-ribose transporter subunit RbsB YP_001727166.1 4692820 R 481805 CDS YP_001727167.1 170022213 6067943 complement(4693735..4694700) 1 NC_010468.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4694700 rbsC 6067943 rbsC Escherichia coli ATCC 8739 ribose ABC transporter permease YP_001727167.1 4693735 R 481805 CDS YP_001727168.1 170022214 6067948 complement(4694705..4696210) 1 NC_010468.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4696210 6067948 EcolC_4245 Escherichia coli ATCC 8739 D-ribose transporter ATP-binding protein YP_001727168.1 4694705 R 481805 CDS YP_001727169.1 170022215 6067956 complement(4696218..4696637) 1 NC_010468.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4696637 6067956 EcolC_4246 Escherichia coli ATCC 8739 D-ribose pyranase YP_001727169.1 4696218 R 481805 CDS YP_001727170.1 170022216 6067959 complement(4696804..4698672) 1 NC_010468.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4698672 trkD 6067959 trkD Escherichia coli ATCC 8739 potassium transport protein Kup YP_001727170.1 4696804 R 481805 CDS YP_001727171.1 170022217 6067960 4698895..4700391 1 NC_010468.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4700391 6067960 EcolC_4248 Escherichia coli ATCC 8739 regulatory ATPase RavA YP_001727171.1 4698895 D 481805 CDS YP_001727172.1 170022218 6067963 4700385..4701836 1 NC_010468.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4701836 yieM 6067963 yieM Escherichia coli ATCC 8739 hypothetical protein YP_001727172.1 4700385 D 481805 CDS YP_001727173.1 170022219 6067966 complement(4701841..4702833) 1 NC_010468.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4702833 6067966 EcolC_4250 Escherichia coli ATCC 8739 asparagine synthetase AsnA YP_001727173.1 4701841 R 481805 CDS YP_001727174.1 170022220 6067974 4702985..4703443 1 NC_010468.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4703443 6067974 EcolC_4251 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator AsnC YP_001727174.1 4702985 D 481805 CDS YP_001727175.1 170022221 6067976 4703533..4703976 1 NC_010468.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4703976 6067976 EcolC_4252 Escherichia coli ATCC 8739 flavodoxin YP_001727175.1 4703533 D 481805 CDS YP_001727176.1 170022222 6067980 4704355..4706244 1 NC_010468.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4706244 6067980 EcolC_4253 Escherichia coli ATCC 8739 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001727176.1 4704355 D 481805 CDS YP_001727177.1 170022223 6067982 4706308..4706931 1 NC_010468.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4706931 gidB 6067982 gidB Escherichia coli ATCC 8739 16S rRNA methyltransferase GidB YP_001727177.1 4706308 D 481805 CDS YP_001727178.1 170022224 6067983 4707548..4707928 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4707928 6067983 EcolC_4255 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit I YP_001727178.1 4707548 D 481805 CDS YP_001727179.1 170022225 6067984 4707937..4708752 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4708752 6067984 EcolC_4256 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit A YP_001727179.1 4707937 D 481805 CDS YP_001727180.1 170022226 6067986 4708799..4709038 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 4709038 6067986 EcolC_4257 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit C YP_001727180.1 4708799 D 481805 CDS YP_001727181.1 170022227 6067998 4709100..4709570 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 4709570 6067998 EcolC_4258 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit B YP_001727181.1 4709100 D 481805 CDS YP_001727182.1 170022228 6068001 4709585..4710118 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4710118 6068001 EcolC_4259 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit delta YP_001727182.1 4709585 D 481805 CDS YP_001727183.1 170022229 6068003 4710131..4711672 1 NC_010468.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 4711672 6068003 EcolC_4260 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit alpha YP_001727183.1 4710131 D 481805 CDS YP_001727184.1 170022230 6068010 4711723..4712586 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4712586 6068010 EcolC_4261 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit gamma YP_001727184.1 4711723 D 481805 CDS YP_001727185.1 170022231 6068011 4712613..4713995 1 NC_010468.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4713995 6068011 EcolC_4262 Escherichia coli ATCC 8739 F0F1 ATP synthase subunit beta YP_001727185.1 4712613 D 481805 CDS YP_001727186.1 170022232 6068013 4714016..4714435 1 NC_010468.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 4714435 atpC 6068013 atpC Escherichia coli ATCC 8739 F0F1 ATP synthase subunit epsilon YP_001727186.1 4714016 D 481805 CDS YP_001727187.1 170022233 6068016 4714788..4716158 1 NC_010468.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4716158 glmU 6068016 glmU Escherichia coli ATCC 8739 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001727187.1 4714788 D 481805 CDS YP_001727188.1 170022234 6068019 4716320..4718149 1 NC_010468.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4718149 6068019 EcolC_4265 Escherichia coli ATCC 8739 glucosamine--fructose-6-phosphate aminotransferase YP_001727188.1 4716320 D 481805 CDS YP_001727189.1 170022235 6068031 4718463..4719503 1 NC_010468.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_3654 high-affinity phosphate-specific transport system periplasmic phosphate-binding protein; phosphate ABC transporter substrate-binding protein 4719503 6068031 EcolC_4266 Escherichia coli ATCC 8739 phosphate ABC transporter substrate-binding protein YP_001727189.1 4718463 D 481805 CDS YP_001727190.1 170022236 6068032 4719589..4720548 1 NC_010468.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease PstC 4720548 pstC 6068032 pstC Escherichia coli ATCC 8739 phosphate transporter permease PstC YP_001727190.1 4719589 D 481805 CDS YP_001727191.1 170022237 6068035 4720548..4721438 1 NC_010468.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease PtsA 4721438 pstA 6068035 pstA Escherichia coli ATCC 8739 phosphate transporter permease PtsA YP_001727191.1 4720548 D 481805 CDS YP_001727192.1 170022238 6068045 4721621..4722394 1 NC_010468.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4722394 pstB 6068045 pstB Escherichia coli ATCC 8739 phosphate transporter ATP-binding protein YP_001727192.1 4721621 D 481805 CDS YP_001727193.1 170022239 6068049 4722409..4723134 1 NC_010468.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4723134 6068049 EcolC_4270 Escherichia coli ATCC 8739 transcriptional regulator PhoU YP_001727193.1 4722409 D 481805 CDS YP_001727194.1 170022240 6068058 4723420..4724256 1 NC_010468.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4724256 6068058 EcolC_4271 Escherichia coli ATCC 8739 transcriptional antiterminator BglG YP_001727194.1 4723420 D 481805 CDS YP_001727195.1 170022241 6068067 4724389..4726266 1 NC_010468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 4726266 6068067 EcolC_4272 Escherichia coli ATCC 8739 PTS system beta-glucoside-specific transporter subunit IIABC YP_001727195.1 4724389 D 481805 CDS YP_001727196.1 170022242 6068073 4726285..4727697 1 NC_010468.1 PFAM: glycoside hydrolase family 1; KEGG: sfv:SFV_3786 phospho-beta-glucosidase B; cryptic; glycoside hydrolase family protein 4727697 6068073 EcolC_4273 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001727196.1 4726285 D 481805 CDS YP_001727197.1 170022243 6068077 4727766..4729382 1 NC_010468.1 PFAM: porin LamB type; KEGG: ssn:SSON_3915 putative receptor protein; LamB type porin 4729382 6068077 EcolC_4274 Escherichia coli ATCC 8739 LamB type porin YP_001727197.1 4727766 D 481805 CDS YP_001727198.1 170022244 6068079 4729409..4730578 1 NC_010468.1 PFAM: putative esterase; glycoside hydrolase family 13 domain protein; KEGG: sfx:S4034 putative xylanase; glycoside hydrolase family protein 4730578 6068079 EcolC_4275 Escherichia coli ATCC 8739 glycoside hydrolase family protein YP_001727198.1 4729409 D 481805 CDS YP_001727199.1 170022245 6068089 4730593..4731315 1 NC_010468.1 PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfv:SFV_3789 putative isomerase; putative 6-phosphogluconolactonase 4731315 6068089 EcolC_4276 Escherichia coli ATCC 8739 putative 6-phosphogluconolactonase YP_001727199.1 4730593 D 481805 CDS YP_001727200.1 170022246 6068093 complement(4731377..4731964) 1 NC_010468.1 PFAM: protein of unknown function UPF0167; KEGG: sfv:SFV_3790 hypothetical protein; hypothetical protein 4731964 6068093 EcolC_4277 Escherichia coli ATCC 8739 hypothetical protein YP_001727200.1 4731377 R 481805 CDS YP_001727201.1 170022247 6068095 complement(4732013..4732486) 1 NC_010468.1 might be involved in hypersensitivity to nitrofurzone; putative inner membrane protein 4732486 6068095 EcolC_4278 Escherichia coli ATCC 8739 putative inner membrane protein YP_001727201.1 4732013 R 481805 CDS YP_001727202.1 170022248 6068097 complement(4732553..4733218) 1 NC_010468.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4733218 6068097 EcolC_4279 Escherichia coli ATCC 8739 6-phosphogluconate phosphatase YP_001727202.1 4732553 R 481805 CDS YP_001727203.1 170022249 6068105 4733385..4734722 1 NC_010468.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: sdy:SDY_4199 putative membrane/transport protein; xanthine/uracil/vitamin C permease 4734722 6068105 EcolC_4280 Escherichia coli ATCC 8739 xanthine/uracil/vitamin C permease YP_001727203.1 4733385 D 481805 CDS YP_001727204.1 170022250 6068106 complement(4734776..4735342) 1 NC_010468.1 PFAM: NADPH-dependent FMN reductase; KEGG: sfv:SFV_3798 hypothetical protein; NADPH-dependent FMN reductase 4735342 6068106 EcolC_4281 Escherichia coli ATCC 8739 NADPH-dependent FMN reductase YP_001727204.1 4734776 R 481805 CDS YP_001727205.1 170022251 6068108 complement(4735364..4736113) 1 NC_010468.1 KEGG: sbo:SBO_3663 hypothetical protein; hypothetical protein 4736113 6068108 EcolC_4282 Escherichia coli ATCC 8739 hypothetical protein YP_001727205.1 4735364 R 481805 CDS YP_001727206.1 170022252 6068109 complement(4736270..4737229) 1 NC_010468.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4737229 6068109 EcolC_4283 Escherichia coli ATCC 8739 DNA-binding transcriptional regulator YidZ YP_001727206.1 4736270 R 481805 CDS YP_001727207.1 170022253 6068111 complement(4737204..4738379) 1 NC_010468.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4738379 6068111 EcolC_4284 Escherichia coli ATCC 8739 multidrug efflux system protein MdtL YP_001727207.1 4737204 R 481805 CDS YP_001727208.1 170022254 6068112 complement(4738512..4739759) 1 NC_010468.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4739759 6068112 EcolC_4285 Escherichia coli ATCC 8739 tryptophan permease TnaB YP_001727208.1 4738512 R 481805 CDS YP_001727209.1 170022255 6068115 complement(4739850..4741265) 1 NC_010468.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4741265 tnaA 6068115 tnaA Escherichia coli ATCC 8739 tryptophanase YP_001727209.1 4739850 R 481805 CDS YP_001727210.1 170022256 6068119 complement(4741486..4741560) 1 NC_010468.1 TIGRFAM: tryptophanase leader peptide; PFAM: tryptophanese operon leader peptide; KEGG: sfx:S4016 tryptophanase leader peptide; tryptophanase leader peptide 4741560 6068119 EcolC_4287 Escherichia coli ATCC 8739 tryptophanase leader peptide YP_001727210.1 4741486 R 481805 CDS YP_001727211.1 170022257 6068121 complement(4741803..4743167) 1 NC_010468.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4743167 trmE 6068121 trmE Escherichia coli ATCC 8739 tRNA modification GTPase TrmE YP_001727211.1 4741803 R 481805 CDS YP_001727212.1 170022258 6068124 complement(4743273..4744919) 1 NC_010468.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 4744919 6068124 EcolC_4289 Escherichia coli ATCC 8739 putative inner membrane protein translocase component YidC YP_001727212.1 4743273 R 481805 CDS YP_001727213.1 170022259 6068126 complement(4744922..4745179) 1 NC_010468.1 PFAM: protein of unknown function DUF37; KEGG: sdy:SDY_4187 hypothetical protein; hypothetical protein 4745179 6068126 EcolC_4290 Escherichia coli ATCC 8739 hypothetical protein YP_001727213.1 4744922 R 481805 CDS YP_001727214.1 170022260 6068127 complement(4745143..4745469) 1 NC_010468.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4745469 rnpA 6068127 rnpA Escherichia coli ATCC 8739 ribonuclease P YP_001727214.1 4745143 R 481805 CDS YP_001727215.1 170022261 6068132 complement(4745519..4745659) 1 NC_010468.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4745659 rpmH 6068132 rpmH Escherichia coli ATCC 8739 50S ribosomal protein L34 YP_001727215.1 4745519 R 481805 CDS