-- dump date 20140619_081334 -- class Genbank::CDS -- table cds_note -- id note YP_001723016.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001723017.1 binds the polymerase to DNA and acts as a sliding clamp YP_001723018.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001723019.1 negatively supercoils closed circular double-stranded DNA YP_001723020.1 PFAM: protein of unknown function DUF937; KEGG: ssn:SSON_3648 hypothetical protein YP_001723021.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001723022.1 KEGG: sfl:SF3768 putative replicase YP_001723023.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfx:S4002 regulator protein for dgo operon YP_001723024.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: ssn:SSON_3644 2-oxo-3-deoxygalactonate kinase YP_001723025.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001723026.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ent:Ent638_0009 mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein YP_001723027.1 TIGRFAM: phosphoglycerate transporter; d-galactonate transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3642 D-galactonate transport YP_001723028.1 FAD/NAD(P)-binding domain YP_001723029.1 KEGG: ssn:SSON_3640 hypothetical protein YP_001723030.1 PFAM: protein of unknown function DUF1375; KEGG: sfv:SFV_3823 hypothetical protein YP_001723031.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001723032.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_001723033.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: sfx:S3992 putative transport protein YP_001723034.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sdy:SDY_4170 putative transcriptional regulator YP_001723035.1 TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, alpha-glucoside-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: ssn:SSON_3634 phosphotransferase system enzyme IIBC component YP_001723036.1 PFAM: glycoside hydrolase family 4; KEGG: sdy:SDY_4168 putative 6-phospho-beta-glucosidase YP_001723037.1 KEGG: sdy:SDY_2598 putative virulence protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB YP_001723038.1 PFAM: protein of unknown function DUF202; KEGG: sdy:SDY_4160 hypothetical protein YP_001723039.1 KEGG: sbo:SBO_3694 hypothetical protein YP_001723040.1 KEGG: sfv:SFV_3836 putative transcriptional regulator YP_001723041.1 multidrug efflux protein involved in adaptation to low energy shock YP_001723042.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sfx:S3978 acetolactate synthase I, valine-sensitive, large subunit YP_001723043.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_001723044.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_001723045.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_001723046.1 membrane protein regulates uhpT expression YP_001723047.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_001723048.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_001723049.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfx:S3971 hypothetical protein YP_001723050.1 PFAM: protein of unknown function DUF1198; KEGG: sdy:SDY_4144 hypothetical protein YP_001723051.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS YP_001723052.1 KEGG: sbo:SBO_3710 putative transport protein YP_001723053.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sdy:SDY_4499 lipoprotein-28 YP_001723054.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sdy:SDY_4498 putative permease transporter YP_001723055.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_0909 putative transport YP_001723056.1 KEGG: stt:t2656 hypothetical protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 protein; TOPRIM domain protein; P4 alpha zinc-binding domain protein; primase P4; SMART: Toprim sub domain protein YP_001723057.1 KEGG: sbo:SBO_4166 putative protein encoded in prophage YP_001723058.1 KEGG: stt:t2654 hypothetical protein YP_001723059.1 KEGG: stt:t2653 hypothetical protein YP_001723060.1 KEGG: sbo:SBO_4168 putative bacteriophage protein YP_001723061.1 PFAM: Prophage CP4-57 regulatory; KEGG: sbo:SBO_4169 hypothetical protein YP_001723062.1 KEGG: sbo:SBO_4170 hypothetical protein YP_001723063.1 PFAM: transcriptional activator Ogr/delta; KEGG: spt:SPA4293 hypothetical protein YP_001723064.1 PFAM: polarity suppression protein; KEGG: stt:t2648 hypothetical protein YP_001723065.1 KEGG: sfr:Sfri_0781 kap P-loop domain protein YP_001723066.1 PFAM: integrase family protein; KEGG: spe:Spro_0108 integrase family protein YP_001723067.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_001723068.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_001723069.1 PFAM: AsmA family protein; KEGG: sfx:S4074 hypothetical protein YP_001723070.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3751 putative transport protein YP_001723071.1 PFAM: sodium/glutamate symporter; KEGG: sdy:SDY_4085 glutamate transport YP_001723072.1 catalyzes branch migration in Holliday junction intermediates YP_001723073.1 specifically modifies tRNA at position G18 YP_001723074.1 KEGG: sbo:SBO_3727 (p)ppGpp synthetase II; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001723075.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001723076.1 Essential for recycling GMP and indirectly, cGMP YP_001723077.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001723078.1 PFAM: protein of unknown function UPF0126; KEGG: sdy:SDY_4077 hypothetical protein YP_001723079.1 KEGG: sbo:SBO_3734 DNA-damage-inducible protein YP_001723080.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ssn:SSON_3762 putative alpha helix protein YP_001723081.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001723082.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001723083.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001723084.1 catalyzes the formation of dUMP from dUTP YP_001723085.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001723086.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001723087.1 required for 70S ribosome assembly YP_001723088.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001723089.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001723090.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001723091.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001723092.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: sdy:SDY_4062 lipopolysaccharide core biosynthesis protein YP_001723093.1 PFAM: glycosyl transferase group 1; KEGG: sdy:SDY_4061 glucosyltransferase I YP_001723094.1 PFAM: lipopolysaccharide kinase; KEGG: sdy:SDY_4060 putative LPS biosynthesis enzyme YP_001723095.1 PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3631 UDP-D-galactose:(glucosyl)lipopolysaccharide-alpha-1, 3-D-galactosylt ransferase YP_001723096.1 PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3630 lipopolysaccharide 1,2-glucosyltransferase YP_001723097.1 PFAM: lipopolysaccharide core biosynthesis protein; KEGG: sdy:SDY_4057 lipopolysaccharide core biosynthesis protein RfaY YP_001723098.1 PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: ssn:SSON_3781 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase YP_001723099.1 PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_3782 putative beta1,3-glucosyltransferase YP_001723100.1 PFAM: O-antigen polymerase; KEGG: ssn:SSON_3783 lipid A-core, surface polymer ligase YP_001723101.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: ssn:SSON_3784 heptosyl transferase I YP_001723102.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001723103.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001723104.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001723105.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001723106.1 PFAM: glycosyl transferase family 2; KEGG: sdy:SDY_4048 putative regulator YP_001723107.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: sfx:S4115 hypothetical protein YP_001723108.2 PFAM: peptidase M23B; KEGG: ssn:SSON_3792 hypothetical protein YP_001723109.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001723110.1 PFAM: Rhodanese domain protein; KEGG: sbo:SBO_3617 hypothetical protein YP_001723111.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: sdy:SDY_4043 glutaredoxin 3 YP_001723112.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001723113.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001723114.1 catalyzes the O-acetylation of serine YP_001723115.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_001723116.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001723117.1 represses the lctPRD operon YP_001723118.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sbo:SBO_3608 L-lactate permease YP_001723119.1 KEGG: sfv:SFV_3931 putative inner membrane lipoprotein YP_001723120.1 KEGG: sbo:SBO_3601 hypothetical protein YP_001723121.1 KEGG: sbo:SBO_3600 putative cytoplasmic protein YP_001723122.1 Acts as a repressor of the mtlAD operon YP_001723123.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfv:SFV_3937 mannitol-1-phosphate dehydrogenase YP_001723124.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ssn:SSON_3809 PTS system, mannitol-specific enzyme IIABC components YP_001723125.1 KEGG: sbo:SBO_3596 hypothetical protein YP_001723126.1 PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_3595 hypothetical protein YP_001723128.1 KEGG: sbo:SBO_3594 hypothetical protein YP_001723129.1 PFAM: RHS protein; KEGG: sbo:SBO_3593 RhsA YP_001723130.1 PFAM: PBS lyase HEAT domain protein repeat-containing protein; KEGG: amr:AM1_4076 hypothetical protein YP_001723131.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001723132.1 PFAM: Glutathione S-transferase domain; KEGG: ssn:SSON_3816 putative S-transferase YP_001723133.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001723134.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: ssn:SSON_3818 selenocysteinyl-tRNA-specific translation factor YP_001723135.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sbo:SBO_3589 putative oxidoreductase YP_001723136.1 PFAM: Aldehyde Dehydrogenase_; KEGG: sfv:SFV_3945 aldehyde dehydrogenase B YP_001723137.1 KEGG: sfv:SFV_3947 hypothetical protein YP_001723138.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_3948 hypothetical protein YP_001723139.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0144 transcriptional regulator, LysR family YP_001723140.1 PFAM: MltA-interacting MipA family protein; KEGG: sfv:SFV_3952 putative outer membrane protein YP_001723141.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001723142.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001723143.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_001723144.1 PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3959 L-xylulose kinase, cryptic YP_001723145.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sfv:SFV_3960 putative solute-binding transport protein YP_001723146.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sfv:SFV_3961 hypothetical protein YP_001723147.1 PFAM: conserved hypothetical protein; KEGG: cko:CKO_05034 hypothetical protein YP_001723148.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_001723149.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sbo:SBO_3582 putative regulator YP_001723150.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_3581 hypothetical protein YP_001723151.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001723152.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001723153.1 PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2; KEGG: sbo:SBO_3578 putative ATP-binding protein YP_001723154.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_3577 putative regulator of xyl operon YP_001723155.1 PFAM: inner-membrane translocator; KEGG: sbo:SBO_3576 putative xylose transport, membrane component YP_001723156.1 with XylFH is part of the high affinity xylose ABC transporter YP_001723157.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_001723158.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001723159.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3976 xylulokinase YP_001723160.1 PFAM: YiaAB two helix domain protein; KEGG: sbo:SBO_3571 hypothetical protein YP_001723161.1 PFAM: YiaAB two helix domain protein; KEGG: sbo:SBO_3570 hypothetical protein YP_001723162.1 PFAM: acyltransferase 3; KEGG: sdy:SDY_4340 hypothetical protein YP_001723163.1 KEGG: sbo:SBO_3566 putative lipoprotein YP_001723164.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001723165.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001723166.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001723167.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_001723168.1 PFAM: Hok/gef cell toxic protein; KEGG: ssn:SSON_3831 putative membrane permeability altering protein YP_001723169.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: cko:CKO_05012 hypothetical protein YP_001723170.1 SMART: helix-turn-helix domain protein; KEGG: sdy:SDY_4348 hypothetical protein YP_001723171.1 KEGG: sdy:SDY_4349 hypothetical protein YP_001723172.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sbo:SBO_3555 putative dehydrogenase YP_001723173.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: ssn:SSON_3836 putative outer membrane protein YP_001723174.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_3536 biotin sulfoxide reductase YP_001723175.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_3840 hypothetical protein YP_001723176.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine YP_001723177.1 KEGG: sbo:SBO_3550 putative lipase YP_001723178.1 TIGRFAM: Oxalate/Formate Antiporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_3843 putative resistance protein YP_001723179.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001723180.1 PFAM: extracellular solute-binding protein family 5; KEGG: sdy:SDY_4567 dipeptide transport protein YP_001723181.1 transports peptides consisting of two or three amino acids YP_001723182.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_3541 dipeptide transport system permease protein 2 YP_001723183.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001723184.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001723185.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_3851 putative transporter protein YP_001723186.1 KEGG: sfl:SF3572 hypothetical protein YP_001723187.1 KEGG: sfv:SFV_3549 hypothetical protein YP_001723188.1 KEGG: sfv:SFV_3550 hypothetical protein YP_001723189.1 KEGG: ssn:SSON_3854 putative protease YP_001723190.1 KEGG: sbo:SBO_3534 hypothetical protein YP_001723191.1 TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: YhjQ family protein; KEGG: sfx:S4201 hypothetical protein YP_001723192.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_001723193.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001723194.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001723195.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_001723196.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli YP_001723197.1 involved in the transport of C4-dicarboxylates across the membrane YP_001723198.1 PFAM: peptidase M16 domain protein; KEGG: sdy:SDY_4547 hypothetical protein YP_001723199.1 PFAM: PfkB domain protein; KEGG: ssn:SSON_3865 ketodeoxygluconokinase YP_001723200.1 in Escherichia coli this protein is involved in flagellar function YP_001723201.1 PFAM: AsmA family protein; KEGG: sbo:SBO_3523 hypothetical protein YP_001723202.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3868 putative transport protein YP_001723203.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: sbo:SBO_3521 hypothetical protein YP_001723204.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_3567 putative transcriptional regulator LysR-type YP_001723205.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: sbo:SBO_3519 putative regulator YP_001723206.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_001723207.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: ssn:SSON_3568 putative cytochrome c peroxidase YP_001723208.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_3516 glutamate decarboxylase isozyme YP_001723209.1 regulates genes in response to acid and/or during stationary phase YP_001723210.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_3987 putative AraC-type regulatory protein YP_001723211.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sdy:SDY_3537 putative transport system permease protein YP_001723212.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds YP_001723213.1 KEGG: ssn:SSON_3574 hypothetical protein YP_001723214.1 KEGG: sbo:SBO_3510 hypothetical protein YP_001723215.1 inactive form YP_001723216.1 KEGG: sbo:SBO_3508 hypothetical protein YP_001723217.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_001723218.1 PFAM: regulatory protein LuxR; KEGG: ssn:SSON_3579 hypothetical protein YP_001723219.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sbo:SBO_3505 Slp YP_001723220.1 KEGG: sfv:SFV_3519 hypothetical protein YP_001723221.1 KEGG: sbo:SBO_3501 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_001723222.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein YP_001723223.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_001723224.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001723225.1 PFAM: protein of unknown function DUF519; KEGG: sbo:SBO_3497 hypothetical protein YP_001723226.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: sbo:SBO_3496 oligopeptidase A YP_001723227.1 predicted SAM-dependent methyltransferase YP_001723228.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_001723229.1 PFAM: UspA domain protein; KEGG: cko:CKO_04943 hypothetical protein YP_001723230.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001723231.1 PFAM: phosphate transporter; KEGG: sdy:SDY_3569 low-affinity phosphate transport YP_001723232.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbo:SBO_3490 hypothetical protein YP_001723233.1 KEGG: sbo:SBO_3489 hypothetical protein YP_001723234.1 KEGG: sfl:SF3505 hypothetical protein YP_001723235.1 KEGG: ssn:SSON_3724 hypothetical protein YP_001723236.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_3488 hypothetical protein YP_001723237.1 PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; KEGG: sfx:S4261 putative ATP-binding component of a transport system YP_001723238.1 PFAM: ABC-2 type transporter; KEGG: sbo:SBO_3480 putative transporter YP_001723240.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001723241.1 Inhibits transcription at high concentrations of nickel YP_001723242.1 with NikABCD is involved with nickel transport into the cell YP_001723243.1 with NikABCE is involved in nickel transport into the cell YP_001723244.1 with NikABDE is involved in nickel transport into the cell YP_001723245.1 with NikACDE is involved in nickel transport into the cell YP_001723246.1 KEGG: sfx:S4269 periplasmic binding protein for nickel; TIGRFAM: nickel ABC transporter, periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5 YP_001723247.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sbo:SBO_3472 hypothetical protein YP_001723248.1 PFAM: protein of unknown function UPF0118; KEGG: ssn:SSON_3712 hypothetical protein YP_001723249.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S4272 hypothetical protein YP_001723250.1 KEGG: sdy:SDY_3623 hypothetical protein YP_001723251.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: sfx:S4274 hypothetical protein YP_001723252.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001723253.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001723254.1 PFAM: YhhN family protein; KEGG: sfx:S4277 putative enzyme YP_001723255.1 KEGG: sbo:SBO_3464 putative receptor YP_001723256.1 PFAM: protein of unknown function DUF1145; KEGG: sdy:SDY_3617 hypothetical protein YP_001723257.1 catalyzes the methylation of 16S rRNA at position G966 YP_001723258.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_001723259.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001723260.1 putative ABC transporter, membrane protein YP_001723261.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001723262.1 PFAM: Extracellular ligand-binding receptor; KEGG: sbo:SBO_3457 high-affinity amino acid transport system periplasmic binding protein YP_001723263.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_3456 hypothetical protein YP_001723264.1 PFAM: Extracellular ligand-binding receptor; KEGG: sbo:SBO_3453 high-affinity leucine-specific transport system periplasmic binding protein YP_001723265.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001723266.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001723267.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001723268.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001723269.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001723270.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001723271.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001723272.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001723273.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001723274.1 KEGG: sbo:SBO_3444 hypothetical protein YP_001723275.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_001723276.1 PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein YP_001723277.1 YhhY; regulated by the fur regulator; unknown function YP_001723278.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ssn:SSON_3682 putative regulator YP_001723279.1 PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: sbo:SBO_3436 hypothetical protein YP_001723280.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cko:CKO_04857 hypothetical protein YP_001723281.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001723282.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: sdy:SDY_3587 H+/gluconate symporter YP_001723283.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_001723284.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001723285.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001723286.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001723287.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001723288.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001723289.1 KEGG: sdy:SDY_3574 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_001723290.1 KEGG: ssn:SSON_3666 hypothetical membrane protein YP_001723291.1 KEGG: ssn:SSON_3666 hypothetical membrane protein YP_001723292.1 KEGG: sdy:SDY_3648 hypothetical protein YP_001723293.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001723294.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001723295.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001723296.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001723297.1 PFAM: sigma-54 factor interaction domain-containing protein; regulator of RNA terminal phosphate cyclase; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sfv:SFV_3429 putative 2-component regulator YP_001723298.1 PFAM: protein of unknown function UPF0027; KEGG: sfv:SFV_3428 hypothetical protein YP_001723299.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_001723300.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001723301.1 KEGG: ssn:SSON_3549 maltodextrin phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_001723302.1 amylomaltase; acts to release glucose from maltodextrins YP_001723303.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: sbo:SBO_3404 high-affinity transport of gluconate/gluconate permease YP_001723304.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001723305.1 involved in high-affinity gluconate transport YP_001723306.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_001723307.1 PFAM: putative transposase YhgA family protein; KEGG: sbo:SBO_3400 hypothetical protein YP_001723308.1 PFAM: Protein of unknown function DUF1920; KEGG: ssn:SSON_3541 hypothetical protein YP_001723309.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_001723310.1 PFAM: FeoA family protein; KEGG: sdy:SDY_3668 ferrous iron transport protein A YP_001723311.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: sfv:SFV_3412 hypothetical protein YP_001723312.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001723313.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001723314.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001723315.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001723316.1 KEGG: sbo:SBO_3389 putative transport YP_001723317.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001723318.1 PFAM: RNA-binding S4 domain protein; KEGG: sdy:SDY_3678 hypothetical protein YP_001723319.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdy:SDY_3679 putative phosphatase YP_001723320.1 PFAM: Intracellular growth attenuator IgaA; KEGG: sfv:SFV_3403 putative dehydrogenase YP_001723321.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001723322.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001723323.1 KEGG: sfv:SFV_3400 hypothetical protein YP_001723324.1 PFAM: Fimbrial assembly family protein; KEGG: sfv:SFV_3399 hypothetical protein YP_001723325.1 KEGG: sfv:SFV_3398 hypothetical protein YP_001723326.1 KEGG: sdy:SDY_3687 hypothetical protein YP_001723327.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001723328.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001723329.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001723330.1 PFAM: Sporulation domain protein; KEGG: sbo:SBO_3375 DamX YP_001723331.1 KEGG: sbo:SBO_3374 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001723332.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001723333.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001723334.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001723335.1 KEGG: cko:CKO_04803 hypothetical protein YP_001723336.1 KEGG: sbo:SBO_3369 hypothetical protein YP_001723337.1 PFAM: alanine racemase domain protein; KEGG: sbo:SBO_3368 hypothetical protein YP_001723338.1 PFAM: metalloenzyme domain protein; Phosphopentomutase domain protein; KEGG: sfv:SFV_3385 putative mutase YP_001723339.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE) YP_001723340.1 KEGG: sfv:SFV_3383 hypothetical protein YP_001723341.1 KEGG: sfx:S4367 putative transport system permease protein YP_001723342.1 KEGG: sbo:SBO_3363 hypothetical protein YP_001723343.1 may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes YP_001723344.1 PFAM: PfkB domain protein; KEGG: sfv:SFV_3379 putative kinase YP_001723345.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine YP_001723346.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine YP_001723347.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon YP_001723348.1 KEGG: sbo:SBO_3357 hypothetical protein YP_001723349.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_001723350.1 member of the FNT family of formate and nitrite transporters YP_001723351.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_001723352.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ssn:SSON_3496 nitrite reductase (NAD(P)H) subunit YP_001723353.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_3346 putative transport YP_001723354.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ssn:SSON_3494 peptidyl-prolyl cis-trans isomerase A YP_001723355.1 KEGG: ssn:SSON_3493 hypothetical protein YP_001723356.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: sfv:SFV_3367 cell filamentation protein fic YP_001723357.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001723358.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001723359.1 TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_3489 hypothetical protein YP_001723360.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001723361.1 PFAM: OsmC family protein; KEGG: sdy:SDY_3518 hypothetical protein YP_001723362.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: sbo:SBO_3335 probable phosphoribulokinase YP_001723363.1 PFAM: protein of unknown function UPF0270; KEGG: sbo:SBO_3334 hypothetical protein YP_001723364.1 PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_3484 hypothetical protein YP_001723365.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_3483 putative ATP-binding component of a transport system YP_001723366.1 required for KefB activity YP_001723367.1 involved in potassium efflux YP_001723368.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3511 hypothetical protein YP_001723369.1 rotamase YP_001723370.1 PFAM: SlyX family protein; KEGG: sdy:SDY_3509 host factor for lysis of phiX174 infection YP_001723371.1 rotamase YP_001723372.1 PFAM: YheO domain protein; KEGG: sbo:SBO_3326 hypothetical protein YP_001723373.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001723374.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001723375.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001723376.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001723377.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001723378.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001723379.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001723380.1 PFAM: Carbohydrate-binding family V/XII; KEGG: cbh:CLC_1134 putative glycosyl hydrolase YP_001723381.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: cko:CKO_04744 hypothetical protein YP_001723382.1 iron storage protein YP_001723383.1 PFAM: peptidase A24A prepilin type IV; KEGG: kpn:KPN_00149 pullulanase Q protein YP_001723384.1 PFAM: General secretion pathway M protein YP_001723385.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: cko:CKO_02220 hypothetical protein YP_001723386.1 PFAM: General secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K YP_001723387.1 TIGRFAM: general secretion pathway protein J; KEGG: vpa:VP0139 general secretion pathway protein J YP_001723388.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: pap:PSPA7_2034 general secretion pathway protein I YP_001723389.1 TIGRFAM: general secretion pathway protein H; KEGG: kpn:KPN_00156 pullulanase H protein YP_001723390.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: cko:CKO_02225 hypothetical protein YP_001723391.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: cko:CKO_02226 hypothetical protein YP_001723392.1 KEGG: cko:CKO_02227 hypothetical protein; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001723393.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: cko:CKO_02228 hypothetical protein YP_001723394.1 TIGRFAM: general secretion pathway protein C; KEGG: kpn:KPN_00161 pullulanase C protein YP_001723395.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: cko:CKO_02233 hypothetical protein YP_001723396.1 calcium-binding protein that may be required for the initiation of chromosome replication YP_001723397.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001723398.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001723399.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001723400.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001723401.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001723402.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001723403.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001723404.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001723405.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001723406.1 one of the stabilizing components for the large ribosomal subunit YP_001723407.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001723408.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001723409.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001723410.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001723411.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001723412.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001723413.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001723414.1 binds 5S rRNA along with protein L5 and L25 YP_001723415.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001723416.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001723417.1 late assembly protein YP_001723418.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001723419.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001723420.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001723421.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001723422.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001723423.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001723424.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001723425.1 KEGG: ssn:SSON_3434 hypothetical protein YP_001723426.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001723427.1 PFAM: protein of unknown function DUF331; KEGG: ssn:SSON_3432 hypothetical protein YP_001723428.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001723429.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001723430.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001723431.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001723432.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001723433.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: sdy:SDY_3462 predicted Rossmann-fold nucleotide-binding protein YP_001723434.1 PFAM: protein of unknown function DUF494; KEGG: sbo:SBO_3278 hypothetical protein YP_001723435.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: sdy:SDY_3460 putative DNA topoisomerase YP_001723436.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_001723437.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001723438.1 PFAM: protein of unknown function DUF1488; KEGG: sbo:SBO_3274 hypothetical protein YP_001723439.1 KEGG: ssn:SSON_3420 putative transferase YP_001723440.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_3265 putative ATP-binding component of a transport system YP_001723441.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_3447 putative transport system permease protein YP_001723442.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cko:CKO_04682 hypothetical protein YP_001723443.1 SMART: extracellular solute-binding protein family 3; KEGG: sfv:SFV_3290 putative periplasmic binding transport protein YP_001723444.1 KEGG: stm:STM3392 putative outer membrane lipoprotein YP_001723445.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_3260 integral transmembrane protein YP_001723446.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_3406 AcrE YP_001723447.1 PFAM: regulatory protein TetR; Tetracycline transcriptional repressor MAATS-type domain protein; KEGG: sbo:SBO_3258 putative transcriptional regulator YP_001723448.1 KEGG: sbo:SBO_3257 hypothetical protein YP_001723449.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ssn:SSON_3403 putative methyltransferase YP_001723450.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001723451.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: sdy:SDY_3437 putative dehydrogenase YP_001723452.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001723453.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001723454.1 PFAM: protein of unknown function DUF997; KEGG: sdy:SDY_3434 hypothetical protein YP_001723455.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001723456.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001723457.1 KEGG: sdy:SDY_3429 hypothetical protein YP_001723458.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_3394 putative dehydrogenase YP_001723459.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001723460.1 functions in MreBCD complex in some organisms YP_001723461.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001723462.1 part of cell wall structural complex MreBCD; transmembrane component YP_001723463.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001723464.1 involved in the processing of the 5'end of 16S rRNA YP_001723465.1 KEGG: ssn:SSON_3387 uncharacterized membrane protein YP_001723466.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001723467.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3144 QseA YP_001723468.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001723469.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001723470.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001723471.1 KEGG: sbo:SBO_3150 hypothetical protein YP_001723472.1 PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_3151 hypothetical protein YP_001723473.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001723474.1 oxidizes malate to oxaloacetate YP_001723475.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sdy:SDY_3411 protease YP_001723476.1 KEGG: sdy:SDY_3410 serine endoprotease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001723477.1 PFAM: protein of unknown function DUF1043; KEGG: sbo:SBO_3156 hypothetical protein YP_001723478.1 PFAM: AFG1-family ATPase; KEGG: sfv:SFV_3259 hypothetical protein YP_001723479.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001723480.1 forms a direct contact with the tRNA during translation YP_001723481.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001723482.1 PFAM: Stringent starvation protein B; KEGG: sbo:SBO_3161 stringent starvation protein B YP_001723483.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic YP_001723484.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001723485.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_001723486.1 TIGRFAM: sialic acid transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3365 sialic acid transporter YP_001723487.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001723488.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_001723489.1 PFAM: conserved hypothetical protein; KEGG: sfv:SFV_3246 hypothetical protein YP_001723490.1 PFAM: protein of unknown function DUF1016; KEGG: sdy:SDY_3395 hypothetical protein YP_001723491.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001723492.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001723493.1 KEGG: sbo:SBO_3171 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001723494.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001723495.1 PFAM: ThiJ/PfpI domain protein; KEGG: sfv:SFV_3239 sigma cross-reacting protein 27A (SCRP-27A) YP_001723496.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001723497.1 KEGG: sfx:S3465 hypothetical protein YP_001723498.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: sdy:SDY_3387 phosphocarrier protein HPr-like NPr YP_001723499.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_3177 hypothetical protein YP_001723500.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sbo:SBO_3178 phosphotransferase system enzyme IIA YP_001723501.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001723502.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001723503.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_3382 putative ATP-binding component of a transport system YP_001723504.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001723505.1 PFAM: protein of unknown function DUF1239; KEGG: sdy:SDY_3380 hypothetical protein YP_001723506.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001723507.1 KEGG: sbo:SBO_3185 putative isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001723508.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001723509.1 ATP-binding subunit of a putative ABC toluene efflux transporter YP_001723510.1 PFAM: protein of unknown function DUF140; KEGG: sbo:SBO_3188 hypothetical protein YP_001723511.1 PFAM: Mammalian cell entry related domain protein; KEGG: sbo:SBO_3189 hypothetical protein YP_001723512.1 PFAM: toluene tolerance family protein; KEGG: sbo:SBO_3190 hypothetical protein YP_001723513.1 KEGG: sdy:SDY_3372 hypothetical protein YP_001723514.1 PFAM: BolA family protein; KEGG: sdy:SDY_3371 hypothetical protein YP_001723515.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001723516.1 activator of maltose metabolism genes YP_001723517.1 PFAM: Polyprenyl synthetase; KEGG: sbo:SBO_3195 octaprenyl diphosphate synthase YP_001723518.1 PFAM: ribosomal protein L21; KEGG: sdy:SDY_3367 50S ribosomal subunit protein L21 YP_001723519.1 involved in the peptidyltransferase reaction during translation YP_001723520.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_3198 hypothetical protein YP_001723521.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001723522.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001723523.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001723524.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability YP_001723525.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001723526.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001723527.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001723528.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001723529.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: ssn:SSON_3323 SecG YP_001723530.1 PFAM: sulfatase; KEGG: sbo:SBO_3209 putative alkaline phosphatase I YP_001723531.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_001723532.2 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001723533.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001723534.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001723535.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001723536.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001723537.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001723538.1 KEGG: ssn:SSON_3310 polynucleotide phosphorylase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein YP_001723539.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001723540.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001723541.1 tryptophan transporter of high affinity YP_001723542.1 PFAM: luciferase family protein; KEGG: sbo:SBO_3222 putative enzyme YP_001723543.1 PFAM: peptidase U32; KEGG: sdy:SDY_3338 hypothetical protein YP_001723544.1 PFAM: peptidase U32; KEGG: ssn:SSON_3304 putative collagenase YP_001723545.1 PFAM: Sterol-binding domain protein; KEGG: sdy:SDY_3336 hypothetical protein YP_001723546.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_3335 hypothetical protein YP_001723547.2 PFAM: Excinuclease ABC C subunit domain protein; KEGG: sfv:SFV_3185 hypothetical protein YP_001723548.1 KEGG: sfv:SFV_3184 hypothetical protein YP_001723549.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: sdy:SDY_3332 hypothetical protein YP_001723550.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_3230 hypothetical protein YP_001723551.1 PFAM: permease; KEGG: ssn:SSON_3297 hypothetical protein YP_001723552.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: sdy:SDY_3329 putative periplasmic protein YP_001723553.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001723554.1 PFAM: protein of unknown function UPF0102; KEGG: ssn:SSON_3294 hypothetical protein YP_001723555.1 PFAM: LppC family lipoprotein; KEGG: ssn:SSON_3293 putative glycosylase YP_001723556.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdy:SDY_3325 hypothetical protein YP_001723557.1 KEGG: sfv:SFV_3175 putative fimbrial protein YP_001723558.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ssn:SSON_3289 putative outer membrane protein YP_001723559.1 PFAM: pili assembly chaperone; KEGG: sfv:SFV_3171 putative chaperone YP_001723560.1 PFAM: Fimbrial protein; KEGG: esa:ESA_02345 hypothetical protein YP_001723561.1 PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfx:S3393 putative galactosamine-6-phosphate isomerase YP_001723562.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001723563.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_001723564.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_001723565.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001723566.1 TIGRFAM: sugar isomerase, AgaS family; PFAM: sugar isomerase (SIS); KEGG: cko:CKO_04536 hypothetical protein YP_001723567.1 KEGG: cko:CKO_04535 hypothetical protein; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001723568.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sfx:S3386 putative transport enzyme subunit YP_001723569.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: cko:CKO_04533 hypothetical protein YP_001723570.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sfx:S3384 N-acetylgalactosameine-specific IIC component 2 YP_001723571.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport YP_001723572.1 KEGG: sfx:S3382 putative tagatose 6-phosphate kinase 2; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ YP_001723573.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_001723574.1 KEGG: ssn:SSON_3287 hypothetical protein YP_001723575.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation YP_001723576.1 KEGG: sfx:S3380 putative hydrolase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein YP_001723577.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S3379 putative transport protein YP_001723578.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_001723579.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_001723580.1 PFAM: glycerate kinase; KEGG: sbo:SBO_2989 hypothetical protein YP_001723581.1 KEGG: sfv:SFV_3161 hypothetical protein YP_001723582.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon YP_001723583.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_001723584.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_001723585.1 involved in the import of threonine and serine in combination with the import of a proton YP_001723586.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_001723587.1 KEGG: ssn:SSON_3271 probable formate acetyltransferase 3; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001723588.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sbo:SBO_2978 hypothetical protein YP_001723589.1 KEGG: sfv:SFV_3153 putative L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001723590.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_3268 putative transport system permease protein YP_001723591.1 PFAM: protein of unknown function DUF1063; KEGG: sbo:SBO_2975 hypothetical protein YP_001723592.1 KEGG: sdy:SDY_3299 hypothetical protein YP_001723593.1 PFAM: Pirin domain protein; KEGG: sbo:SBO_2973 hypothetical protein YP_001723594.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2972 putative transcriptional regulator LysR-type YP_001723595.1 PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_3263 putative cytochrome YP_001723596.1 PFAM: protein of unknown function DUF805; KEGG: sbo:SBO_2970 putative cytochrome YP_001723597.1 KEGG: sdy:SDY_3291 putative transferase YP_001723598.1 PFAM: DoxX family protein; KEGG: sdy:SDY_3290 hypothetical protein YP_001723599.1 KEGG: sbo:SBO_2967 hypothetical protein YP_001723600.1 KEGG: sbo:SBO_2966 hypothetical protein YP_001723601.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_3285 hypothetical protein YP_001723602.1 PFAM: protein of unknown function DUF1090; KEGG: sbo:SBO_2964 hypothetical protein YP_001723603.1 KEGG: sdy:SDY_3283 hypothetical protein YP_001723604.1 PFAM: SNARE associated Golgi protein; KEGG: sdy:SDY_3282 hypothetical protein YP_001723605.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_001723606.1 KEGG: ssn:SSON_3252 putative fimbrial protein YP_001723607.1 PFAM: CS1 type fimbrial major subunit; KEGG: sbo:SBO_2959 putative fimbrial subunit YP_001723608.1 KEGG: ssn:SSON_3248 outer membrane fimbrial user protein YP_001723609.1 PFAM: CblD family pilus biogenesis initiator protein; KEGG: ssn:SSON_3247 putative minor pilin and initiator YP_001723610.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3134 transport of hexuronates YP_001723611.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001723612.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: sdy:SDY_3276 altronate hydrolase YP_001723613.1 KEGG: ssn:SSON_3243 hypothetical protein YP_001723614.1 involved in the import of serine and threonine coupled with the import of sodium YP_001723615.1 PFAM: Integral membrane protein TerC; KEGG: ssn:SSON_3117 putative transport protein YP_001723616.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sfv:SFV_3128 hypothetical protein YP_001723617.1 PFAM: protein of unknown function DUF218; KEGG: sbo:SBO_2947 hypothetical protein YP_001723618.1 PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein YP_001723619.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: sdy:SDY_3267 putative enzyme YP_001723620.1 KEGG: ssn:SSON_3122 hypothetical protein YP_001723621.1 PFAM: helix-turn-helix domain protein; KEGG: sfv:SFV_3123 hypothetical protein YP_001723622.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_3124 putative NADPH dehydrogenase YP_001723623.1 KEGG: sfl:SF3120 putative isomerase YP_001723624.1 KEGG: ssn:SSON_3126 hypothetical protein YP_001723625.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_2937 putative oxidoreductase YP_001723626.1 in Escherichia coli this is the second beta-galactosidase system YP_001723627.1 in Escherichia coli this is the second beta-galactosidase system YP_001723628.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sdy:SDY_3259 regulator of ebg operon YP_001723629.1 PFAM: t-RNA-binding domain protein; KEGG: sbo:SBO_2933 putative tRNA synthetase YP_001723630.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_001723631.1 KEGG: ssn:SSON_3210 aerotaxis sensor receptor, flavoprotein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001723632.1 PFAM: transcriptional regulator PadR family protein; KEGG: sbo:SBO_2930 hypothetical protein YP_001723633.1 PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: sbo:SBO_2929 hypothetical protein YP_001723634.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: sbo:SBO_2927 hypothetical protein YP_001723635.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001723636.1 synthesizes RNA primers at the replication forks YP_001723637.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001723638.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001723639.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: sfv:SFV_3103 hypothetical protein YP_001723640.1 Involved in the tartrate degradation pathway YP_001723641.1 Involved in the tartrate degradation pathway YP_001723642.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol YP_001723643.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001723644.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001723645.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001723646.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001723647.1 SMART: SH3 domain protein; KEGG: ssn:SSON_3192 hypothetical protein YP_001723648.1 PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: sdy:SDY_3237 hypothetical protein YP_001723649.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001723650.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001723651.1 PFAM: band 7 protein; KEGG: ssn:SSON_3188 hypothetical protein YP_001723652.1 PFAM: protein of unknown function DUF1449; KEGG: ssn:SSON_3187 putative oxidoreductase YP_001723653.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_001723654.1 KEGG: ssn:SSON_3184 hypothetical protein YP_001723655.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_3183 hypothetical protein YP_001723656.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB3895 outer membrane fimbrial usher porin YP_001723657.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_3180 putative fimbrial-like protein YP_001723658.1 PFAM: protein of unknown function DUF526; KEGG: sfv:SFV_3086 hypothetical protein YP_001723659.1 DHBP synthase; functions during riboflavin biosynthesis YP_001723660.1 KEGG: cko:CKO_04433 hypothetical protein YP_001723661.1 PFAM: zinc/iron permease; KEGG: ssn:SSON_3177 hypothetical protein YP_001723662.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001723663.1 PFAM: glutathionylspermidine synthase; KEGG: sfv:SFV_3082 putative synthetase/amidase YP_001723664.1 KEGG: ssn:SSON_3174 hypothetical protein YP_001723665.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001723666.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001723667.1 PFAM: protein of unknown function DUF1249; KEGG: ssn:SSON_3171 putative enzyme YP_001723668.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: sdy:SDY_3208 regulator of LacZ YP_001723669.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001723670.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001723671.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sbo:SBO_2887 hypothetical protein YP_001723672.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: sbo:SBO_2886 modulator of drug activity B YP_001723673.1 KEGG: sfx:S3272 hypothetical protein YP_001723674.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_3165 quorum sensing regulator C YP_001723675.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_001723676.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3215 hypothetical protein YP_001723677.1 PFAM: transcription activator effector binding; KEGG: ssn:SSON_3162 hypothetical protein YP_001723678.1 KEGG: yps:YPTB3124 hypothetical protein YP_001723679.1 SMART: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_0889 putative transcriptional regulator YP_001723680.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system YP_001723681.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001723682.1 KEGG: sbo:SBO_2880 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001723683.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sfv:SFV_3066 suppressor of FtsI YP_001723684.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sbo:SBO_2878 Fe-S oxidoreductase YP_001723685.1 KEGG: sbo:SBO_3008 hypothetical protein YP_001723686.1 KEGG: sbo:SBO_3007 hypothetical protein YP_001723687.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001723688.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sfv:SFV_3060 putative oxidoreductase YP_001723689.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: sbo:SBO_3005 putative AraC-type regulatory protein YP_001723690.1 PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_3152 hypothetical protein YP_001723691.1 catalyzes the formation of L-homocysteine from cystathionine YP_001723692.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001723693.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001723694.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbo:SBO_2997 putative oxidoreductase YP_001723695.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2996 hypothetical protein YP_001723696.1 PFAM: aldo/keto reductase; KEGG: sfv:SFV_3053 putative reductase YP_001723697.1 KEGG: sdy:SDY_3075 hypothetical protein YP_001723698.1 involved in hydrogen uptake YP_001723699.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_001723700.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_001723701.1 involved in hydrogen uptake YP_001723702.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_001723703.1 KEGG: sbo:SBO_2871 HybE YP_001723704.1 plays a role in hydrogenase nickel cofactor insertion YP_001723705.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: sdy:SDY_3083 hydrogenase-2 operon protein YP_001723706.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001723707.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_001723708.1 PFAM: phosphate transporter; KEGG: ssn:SSON_3132 low-affinity phosphate transport YP_001723709.1 KEGG: sfx:S3234 hypothetical protein YP_001723710.1 KEGG: ssn:SSON_3219 hypothetical protein YP_001723711.1 KEGG: ssn:SSON_3220 hypothetical protein YP_001723712.1 PFAM: polysaccharide biosynthesis protein; KEGG: sfx:S3231 hypothetical protein YP_001723713.1 KEGG: sfx:S3230 hypothetical protein YP_001723714.1 PFAM: conserved hypothetical protein; KEGG: sfx:S3229 hypothetical protein YP_001723715.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sfx:S3228 hypothetical protein YP_001723716.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sfx:S3227 hypothetical protein YP_001723717.1 PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: sfx:S3226 putative class II aminotransferase YP_001723718.1 PFAM: phosphopantetheine-binding; KEGG: sfx:S3224 hypothetical protein YP_001723719.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: sfx:S3223 hypothetical protein YP_001723720.1 activates fatty acids by binding to coenzyme A YP_001723721.1 KEGG: sfv:SFV_3037 hypothetical protein YP_001723722.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfx:S3220 transcriptional activator for glc operon YP_001723723.1 TIGRFAM: glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein; KEGG: psa:PST_0431 glycolate oxidase, subunit GlcD YP_001723724.1 PFAM: FAD linked oxidase domain protein; KEGG: psa:PST_0432 glycolate oxidase, subunit GlcE YP_001723725.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: pmy:Pmen_0201 protein of unknown function DUF224, cysteine-rich region domain protein YP_001723726.1 PFAM: protein of unknown function DUF336; KEGG: sfv:SFV_3032 hypothetical protein YP_001723727.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001723728.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sfv:SFV_3030 putative permease YP_001723729.1 KEGG: ter:Tery_2591 cadherin YP_001723730.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1 YP_001723731.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2 YP_001723732.1 PFAM: HMG-I and HMG-Y DNA-binding domain protein; regulatory protein TetR; KEGG: kpn:KPN_02440 putative bacterial regulatory protein, TetR YP_001723733.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001723734.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_001723735.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: kpn:KPN_pKPN3p05958 secondary glycine betaine transporter BetU YP_001723736.1 PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2 YP_001723737.1 PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30 YP_001723738.1 KEGG: eca:ECA2935 hypothetical protein YP_001723739.1 Part of the FecBCDE citrate-dependent iron (III) transport system YP_001723740.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. YP_001723741.1 part of the FecBCDE citrate-dependent iron (III) transport system YP_001723742.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) YP_001723743.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB short domain; TonB-dependent receptor plug; KEGG: sdy:SDY_4297 citrate-dependent iron transport, outer membrane receptor YP_001723744.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon YP_001723745.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport YP_001723746.1 PFAM: integrase family protein; KEGG: sfx:S4822 putative P4-type integrase YP_001723747.1 PFAM: protein of unknown function DUF554; KEGG: ssn:SSON_3229 putative transport protein YP_001723748.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sfx:S3165 ornithine decarboxylase isozyme YP_001723749.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: sbo:SBO_3026 NupG YP_001723750.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001723751.1 PFAM: Fe(II) trafficking protein YggX; KEGG: sdy:SDY_3110 hypothetical protein YP_001723752.1 KEGG: sbo:SBO_3029 adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001723753.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001723754.1 PFAM: protein of unknown function DUF469; KEGG: sdy:SDY_3113 hypothetical protein YP_001723755.1 KEGG: sdy:SDY_3114 hypothetical protein YP_001723756.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001723757.1 PFAM: protein of unknown function DUF1202; KEGG: sbo:SBO_3034 putative alpha helix chain YP_001723758.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001723759.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001723760.1 PFAM: protein of unknown function DUF167; KEGG: sfv:SFV_3007 hypothetical protein YP_001723761.1 PFAM: protein of unknown function YGGT; KEGG: sdy:SDY_3120 putative resistance protein YP_001723762.1 PFAM: alanine racemase domain protein; KEGG: sdy:SDY_3122 hypothetical protein YP_001723763.1 KEGG: sfv:SFV_3004 putative protein transport; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001723764.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001723765.1 PFAM: protein of unknown function DUF179; KEGG: sdy:SDY_3124 hypothetical protein YP_001723766.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001723767.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001723768.1 PFAM: Endonuclease I; KEGG: sbo:SBO_3045 DNA-specific endonuclease I YP_001723769.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: sbo:SBO_3046 hypothetical protein YP_001723770.1 KEGG: sdy:SDY_3129 galactose-proton symport of transport system; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001723771.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001723772.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001723773.1 catalyzes the formation of putrescine from agmatine YP_001723774.1 PFAM: peptidase M48 Ste24p; KEGG: sbo:SBO_3053 hypothetical protein YP_001723775.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001723776.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein YP_001723777.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: sdy:SDY_3144 PTS system, mannitol-specific enzyme II component, cryptic YP_001723778.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfv:SFV_2983 putative oxidoreductase YP_001723779.1 TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sfv:SFV_2982 hypothetical protein YP_001723780.1 PFAM: Mannitol repressor; KEGG: sdy:SDY_3147 putative transcriptional regulator YP_001723781.1 KEGG: sbo:SBO_3060 putative kinase YP_001723782.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001723783.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001723784.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001723785.1 participates in the regulation of osmotic pressure changes within the cel YP_001723786.1 Involved in the export of arginine YP_001723787.1 PFAM: protein of unknown function DUF541; KEGG: sdy:SDY_3160 putative actin YP_001723788.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3073 putative transcriptional regulator LysR-type YP_001723789.1 KEGG: ssn:SSON_3071 putative coenzyme A transferase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase YP_001723790.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_001723791.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001723792.1 MDM; functions in conversion of succinate to propionate YP_001723793.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001723795.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001723796.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001723797.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_001723798.1 PFAM: protein of unknown function DUF710; KEGG: sbo:SBO_3082 hypothetical protein YP_001723799.2 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001723800.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001723801.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001723802.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: ssn:SSON_3059 hypothetical protein YP_001723803.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001723804.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001723805.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001723806.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sfx:S3087 putative oxidoreductase YP_001723807.1 PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_3054 6-phospho-beta-glucosidase A, cryptic YP_001723808.1 PFAM: protein of unknown function DUF437; KEGG: sdy:SDY_3181 hypothetical protein YP_001723809.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: ssn:SSON_3052 putative oxidoreductase YP_001723810.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001723811.1 PFAM: protein of unknown function DUF339; KEGG: sdy:SDY_3185 hypothetical protein YP_001723812.1 PFAM: protein of unknown function DUF1434; KEGG: sbo:SBO_3096 hypothetical protein YP_001723813.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001723814.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001723815.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001723816.1 5'-3' single-stranded-DNA-specific exonuclease YP_001723817.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001723818.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001723819.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_001723820.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3041 putative permease YP_001723821.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001723822.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_3038 putative oxidoreductase, Fe-S subunit YP_001723823.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: spe:Spro_4431 xanthine/uracil/vitamin C permease YP_001723824.1 Catalyzes the deamination of guanine YP_001723825.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: aha:AHA_2174 xanthine/uracil permease family protein YP_001723826.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_001723827.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_001723828.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_001723829.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_001723830.1 KEGG: ssn:SSON_3028 hypothetical protein YP_001723831.1 KEGG: ssn:SSON_3027 hypothetical protein YP_001723832.1 TIGRFAM: selenium-dependent molybdenum hydroxylase system protein, YqeB family; PFAM: biotin/lipoyl attachment domain-containing protein; protein of unknown function DUF182; KEGG: sbo:SBO_3109 putative synthase YP_001723833.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001723834.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001723835.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_001723836.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001723837.1 TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: ssn:SSON_3021 putative carbamoyl transferase YP_001723838.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: PAS domain containing protein; AAA ATPase; KEGG: ssn:SSON_3020 putative transcriptional regulator YP_001723839.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage YP_001723840.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage YP_001723841.1 putative molybdenum cofactor-binding protein; participates in purine salvage YP_001723842.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: ssn:SSON_3016 putative lipoprotein YP_001723843.1 KEGG: ssn:SSON_3014 hypothetical protein YP_001723844.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells YP_001723845.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_001723846.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ family 3; KEGG: cvi:CV_2623 surface presentation of antigens; secretory proteins YP_001723847.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: cvi:CV_2622 surface presentation of antigens; secretory proteins YP_001723848.1 PFAM: regulatory protein LuxR YP_001723849.1 TIGRFAM: type III secretion system protein PrgH/EprH; PFAM: Type III secretion system PrgH/EprHfmaily protein; KEGG: stt:t2776 pathogenicity 1 island effector protein YP_001723850.1 TIGRFAM: type III secretion system needle protein; KEGG: cvi:CV_2422 cell invasion protein - cytoplasmic YP_001723851.1 KEGG: cvi:CV_2421 cell invasion protein - cytoplasmic YP_001723852.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001723855.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: sgl:SG1279 putative two-component response regulator YP_001723856.1 PFAM: Lytic transglycosylase catalytic; KEGG: stt:t4248 hypothetical protein YP_001723858.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: cvi:CV_2640 invasion genes transcription activator YP_001723859.1 PFAM: Tetratricopeptide TPR_3; KEGG: ssn:SSON_3011 hypothetical protein YP_001723860.1 KEGG: ssn:SSON_3010 hypothetical protein YP_001723863.1 KEGG: ssn:SSON_3009 hypothetical protein YP_001723864.1 PFAM: transcriptional regulator domain protein; KEGG: kpn:KPN_00272 putative sensory transducer YP_001723865.1 KEGG: ssn:SSON_3006 hypothetical protein YP_001723866.1 TIGRFAM: serine transporter; PFAM: Amino acid transporter transmembrane; KEGG: ssn:SSON_3005 putative transporter protein YP_001723867.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001723868.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001723869.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_001723870.1 KEGG: ssn:SSON_3001 low-affinity L-arabinose transport system proton symport protein; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001723871.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: sfv:SFV_2918 putative resistance proteins YP_001723872.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001723873.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001723874.1 controls transcription of galETKM YP_001723875.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001723876.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2727 putative resistance proteins YP_001723877.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001723878.1 PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3050 hypothetical protein YP_001723879.1 PFAM: Integral membrane protein TerC; KEGG: sdy:SDY_3049 putative transport protein YP_001723880.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001723881.1 hydrolyzes diadenosine polyphosphate YP_001723882.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001723883.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001723884.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001723885.1 KEGG: sdy:SDY_3043 prepilin peptidase dependent protein A YP_001723886.1 KEGG: ssn:SSON_2982 prepilin peptidase dependent protein B YP_001723887.1 KEGG: sfv:SFV_2902 hypothetical protein YP_001723888.1 KEGG: sbo:SBO_2713 prepilin peptidase dependent protein C YP_001723889.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001723890.1 PFAM: peptidase M16 domain protein; KEGG: sfv:SFV_2899 protease III YP_001723891.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001723892.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001723893.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001723894.1 PFAM: cell wall hydrolase/autolysin; KEGG: sbo:SBO_2707 putative amidase YP_001723895.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001723896.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ssn:SSON_2969 putative enzyme YP_001723897.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: sdy:SDY_3029 hypothetical protein YP_001723898.1 TIGRFAM: cysteine desulfurase, catalytic subunit CsdA; PFAM: aminotransferase class V; KEGG: ssn:SSON_2967 hypothetical protein YP_001723899.1 PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3027 hypothetical protein YP_001723900.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001723901.1 PFAM: protein of unknown function DUF423; KEGG: sdy:SDY_3025 hypothetical protein YP_001723902.1 KEGG: sfv:SFV_2885 hypothetical protein YP_001723903.1 regulates expression of genes involved in L-fucose utilization YP_001723904.1 PFAM: RbsD or FucU transport; KEGG: sdy:SDY_3022 protein of fucose operon YP_001723905.1 TIGRFAM: L-fuculokinase; PFAM: carbohydrate kinase FGGY; KEGG: ssn:SSON_2960 L-fuculokinase YP_001723906.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_001723907.1 TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_2880 fucose permease YP_001723908.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001723909.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2956 L-1,2-propanediol oxidoreductase YP_001723910.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001723911.1 KEGG: ssn:SSON_2954 L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001723912.1 TIGRFAM: serine transporter; KEGG: sbo:SBO_2677 probable serine transporter YP_001723913.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2676 hypothetical protein YP_001723914.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001723915.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001723916.1 PFAM: protein of unknown function DUF446; KEGG: ssn:SSON_2949 hypothetical protein YP_001723917.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001723918.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001723919.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2946 putative transport protein YP_001723920.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ssn:SSON_2945 putative glucarate dehydratase YP_001723921.1 KEGG: sfx:S2994 putative glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein YP_001723922.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001723923.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001723924.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001723925.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF YP_001723926.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system YP_001723927.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001723928.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001723929.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001723930.1 PFAM: protein of unknown function DUF477; KEGG: sfv:SFV_2677 hypothetical protein YP_001723931.1 KEGG: sdy:SDY_2981 hypothetical protein YP_001723932.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1 YP_001723933.1 PFAM: carbohydrate kinase FGGY; KEGG: sdy:SDY_2978 putative kinase YP_001723934.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2927 putative transport protein YP_001723935.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_2976 putative oxidoreductase YP_001723936.1 PFAM: FAD linked oxidase domain protein; KEGG: cko:CKO_04128 hypothetical protein YP_001723937.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_2924 putative transport protein YP_001723938.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: ssn:SSON_2923 putative transport protein YP_001723939.1 PFAM: Electron transfer flavoprotein alpha subunit; KEGG: ssn:SSON_2922 putative flavoprotein YP_001723940.1 PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: sdy:SDY_2970 putative anti-terminator regulatory protein YP_001723941.1 KEGG: sdy:SDY_2969 hypothetical protein YP_001723942.1 PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2919 hypothetical protein YP_001723943.1 KEGG: sbo:SBO_2649 putative 6-pyruvoyl tetrahydrobiopterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase; queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001723944.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001723945.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001723946.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001723947.1 KEGG: gsu:GSU1384 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001723948.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate YP_001723949.1 TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2; KEGG: gsu:GSU1386 hypothetical protein YP_001723950.1 TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CRISPR-associated protein CT1975; KEGG: gsu:GSU1387 CRISPR-associated CT1975 family protein YP_001723951.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: gsu:GSU1388 CRISPR-associated CT1976 family protein YP_001723952.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: sdy:SDY_2955 hypothetical protein YP_001723953.1 TIGRFAM: CRISPR-associated protein Cas1; KEGG: stt:t2839 hypothetical protein YP_001723954.1 TIGRFAM: CRISPR-associated protein Cas2; KEGG: sdy:SDY_2953 hypothetical protein YP_001723955.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_001723956.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001723957.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001723958.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001723959.1 KEGG: sdy:SDY_2948 putative cytochrome oxidase subunit YP_001723960.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001723961.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001723962.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001723963.1 catalyzes the modification of U13 in tRNA(Glu) YP_001723964.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001723965.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001723966.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001723967.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001723968.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001723969.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sbo:SBO_2781 hypothetical protein YP_001723970.1 PFAM: class II aldolase/adducin family protein; KEGG: sbo:SBO_2782 putative epimerase/aldolase YP_001723971.1 PFAM: type III effector Hrp-dependent outers; KEGG: ssn:SSON_2885 hypothetical protein YP_001723972.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ssn:SSON_2884 putative dehydrogenase YP_001723973.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sbo:SBO_2785 putative DeoR-type transcriptional regulator YP_001723974.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001723975.1 This protein performs the mismatch recognition step during the DNA repair process YP_001723976.1 KEGG: sbo:SBO_2788 hypothetical protein YP_001723977.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2789 formate hydrogen-lyase transcriptional activator for FdhF, hyc and hyp operons YP_001723978.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: ssn:SSON_2877 HypE YP_001723979.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: sbo:SBO_2791 HypD YP_001723980.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_001723981.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_001723982.1 plays a role in hydrogenase nickel cofactor insertion YP_001723983.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_001723984.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2779 probable small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) YP_001723985.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_001723986.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: sbo:SBO_2796 membrane-spanning protein of hydrogenase 3 YP_001723987.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: sbo:SBO_2797 large subunit of hydrogenase 3 YP_001723988.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_001723989.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: sfv:SFV_2784 hydrogenase activity YP_001723990.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: sbo:SBO_2800 processing of large subunit (HycE) of hydrogenase 3 YP_001723991.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_001723992.1 PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_2860 6-phospho-beta-glucosidase, cryptic YP_001723993.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001723994.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ssn:SSON_2858 ascBF operon repressor YP_001723995.1 involved in electron transport from formate to hydrogen YP_001723996.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: ssn:SSON_2856 transcriptional regulatory protein YP_001723997.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001723998.1 detoxifies nitric oxide using NADH YP_001723999.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001724000.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_001724001.1 regulates genes involved in glucitol utilization YP_001724002.1 regulator for glucitol utilization YP_001724003.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_001724004.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001724005.1 KEGG: sbo:SBO_2815 PTS system glucitol/sorbitol-specific IIB component and second of two IIC components; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein YP_001724006.1 TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: sdy:SDY_2898 PTS system, glucitol/sorbitol-specific IIC component YP_001724007.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001724008.1 PFAM: CinA domain protein; KEGG: ssn:SSON_2844 hypothetical protein YP_001724009.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001724010.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001724011.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001724012.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001724013.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001724014.1 KEGG: sfv:SFV_2815 hypothetical protein YP_001724015.1 involved in the first step of glutathione biosynthesis YP_001724016.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001724017.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2830 probably membrane translocase YP_001724018.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_2832 multidrug resistance secretion protein YP_001724019.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001724020.1 KEGG: sbo:SBO_2834 hypothetical protein YP_001724021.1 PFAM: AzlC family protein; KEGG: ssn:SSON_2826 hypothetical protein YP_001724022.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2836 permease YP_001724023.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001724024.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001724025.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_001724026.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001724027.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001724028.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001724029.1 TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: sbo:SBO_2844 glutaredoxin-like protein YP_001724030.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2863 hypothetical protein YP_001724031.1 KEGG: sbo:SBO_2848 hypothetical protein YP_001724032.1 PFAM: protein of unknown function DUF1144; KEGG: sbo:SBO_2849 hypothetical protein YP_001724033.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sdy:SDY_2859 DNA-binding protein YP_001724034.1 SMART: Rhodanese domain protein; KEGG: ssn:SSON_2812 hypothetical protein YP_001724035.1 PFAM: regulatory protein ArsR; KEGG: sbo:SBO_2852 hypothetical protein YP_001724036.1 PFAM: protein of unknown function UPF0057; KEGG: sdy:SDY_2856 hypothetical protein YP_001724037.1 PFAM: Peptidoglycan-binding LysM; transport-associated; SMART: Transport-associated and nodulation region; KEGG: sdy:SDY_2855 hypothetical protein YP_001724038.1 regulator of gab gene expression YP_001724039.1 TIGRFAM: GABA permease; PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2853 transport permease protein of gamma-aminobutyrate YP_001724040.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001724041.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_001724042.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001724043.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_001724044.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sfv:SFV_2845 putative enzyme YP_001724045.1 KEGG: ssn:SSON_2797 hypothetical protein YP_001724046.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sdy:SDY_1204 putative ATP-binding component of a transport system YP_001724047.1 KEGG: stt:t2656 hypothetical protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 protein; TOPRIM domain protein; P4 alpha zinc-binding domain protein; primase P4; SMART: Toprim sub domain protein YP_001724048.1 KEGG: sbo:SBO_4166 putative protein encoded in prophage YP_001724049.1 KEGG: stt:t2654 hypothetical protein YP_001724050.1 KEGG: stt:t2653 hypothetical protein YP_001724051.1 KEGG: sbo:SBO_4168 putative bacteriophage protein YP_001724052.1 PFAM: Prophage CP4-57 regulatory; KEGG: sbo:SBO_4169 hypothetical protein YP_001724053.1 KEGG: sbo:SBO_4170 hypothetical protein YP_001724054.1 PFAM: transcriptional activator Ogr/delta; KEGG: stt:t2649 hypothetical protein YP_001724055.1 PFAM: polarity suppression protein; KEGG: stt:t2648 hypothetical protein YP_001724057.1 PFAM: integrase family protein; KEGG: esa:ESA_00630 hypothetical protein YP_001724058.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001724059.1 PFAM: cyclase/dehydrase; KEGG: sdy:SDY_2792 hypothetical protein YP_001724060.1 PFAM: protein of unknown function UPF0125; KEGG: sbo:SBO_2753 hypothetical protein YP_001724061.1 PFAM: SmpA/OmlA domain protein; KEGG: cko:CKO_03939 hypothetical protein YP_001724062.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: ssn:SSON_2772 protein used in recombination and DNA repair YP_001724063.1 catalyzes the phosphorylation of NAD to NADP YP_001724064.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001724065.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: ssn:SSON_2769 uncharacterized CBS domain-containing protein YP_001724066.1 PFAM: cytochrome c assembly protein; KEGG: sdy:SDY_2785 hypothetical protein YP_001724067.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001724068.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001724069.1 Essential for efficient processing of 16S rRNA YP_001724070.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001724071.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001724072.1 PFAM: OmpA/MotB domain protein; KEGG: sbo:SBO_2741 putative outer membrane protein YP_001724073.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_2761 hypothetical protein YP_001724074.1 KEGG: ssn:SSON_2755 hypothetical protein YP_001724075.1 KEGG: sfv:SFV_2869 hypothetical protein YP_001724076.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001724077.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001724078.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001724079.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_001724080.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001724081.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001724082.1 PFAM: protein of unknown function DUF152; KEGG: sdy:SDY_2836 hypothetical protein YP_001724083.1 KEGG: sbo:SBO_2627 heat shock protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001724084.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2830 alpha-ketoglutarate permease YP_001724085.1 KEGG: sfv:SFV_2649 hypothetical protein YP_001724086.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001724087.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: sbo:SBO_2616 hypothetical protein YP_001724088.1 PFAM: DTW domain containing protein; KEGG: sdy:SDY_2826 hypothetical protein YP_001724089.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sdy:SDY_2825 putative thioredoxin-like protein YP_001724090.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sdy:SDY_2824 hypothetical protein YP_001724091.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001724092.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001724093.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ssn:SSON_2704 hypothetical protein YP_001724094.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_2703 putative transcriptional regulator LysR-type YP_001724095.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001724096.1 PFAM: methyltransferase small; KEGG: sfv:SFV_2638 putative enzyme YP_001724097.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001724098.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001724099.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: sdy:SDY_2813 sigma-E factor, negative regulatory protein YP_001724100.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001724101.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001724102.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001724103.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001724104.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001724105.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001724106.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001724107.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001724108.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001724109.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_2590 hypothetical protein YP_001724110.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sbo:SBO_2589 hypothetical protein YP_001724111.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: sfv:SFV_2608 hypothetical protein YP_001724112.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sbo:SBO_2587 putative deaminase YP_001724113.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001724114.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001724115.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_2746 putative 2-component sensor protein YP_001724116.1 KEGG: sfv:SFV_2603 putative alpha helix protein YP_001724117.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2582 putative 2-component transcriptional regulator YP_001724118.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001724119.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001724120.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001724121.1 PFAM: ROK family protein; KEGG: sbo:SBO_2578 putative NAGC-like transcriptional regulator YP_001724122.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sbo:SBO_2577 hypothetical protein YP_001724123.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sfv:SFV_2596 putative LacI-type transcriptional regulator YP_001724124.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_2573 putative ATP-binding component of a transport system YP_001724125.1 PFAM: inner-membrane translocator; KEGG: ssn:SSON_2629 putative transport system permease protein YP_001724126.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_2628 putative oxidoreductase YP_001724127.1 PFAM: Aldose 1-epimerase; KEGG: ssn:SSON_2627 hypothetical protein YP_001724128.1 PFAM: DoxX family protein; KEGG: sfx:S2762 hypothetical protein YP_001724129.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2624 ferredoxin reductase subunit of phenylpropionate dioxygenase YP_001724130.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_001724131.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_2622 ferredoxin subunit of phenylpropionate dioxygenase YP_001724132.1 PFAM: aromatic-ring-hydroxylating dioxygenase beta subunit; KEGG: sfx:S2758 small terminal subunit of phenylpropionate dioxygenase YP_001724133.1 PFAM: Rieske [2Fe-2S] domain protein; Aromatic-ring-hydroxylating dioxygenase, alpha subunit-like; KEGG: ssn:SSON_2620 large terminal subunit of phenylpropionate dioxygenase YP_001724134.1 activator of 3-phenylpropionic acid catabolism YP_001724135.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_001724136.1 PFAM: PRD domain protein; KEGG: sbo:SBO_2559 hypothetical protein YP_001724137.1 KEGG: sdy:SDY_2730 putative enzyme YP_001724138.1 PFAM: inositol monophosphatase; KEGG: sbo:SBO_2557 SuhB YP_001724139.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sbo:SBO_2556 putative ATP synthase beta subunit YP_001724140.1 regulates the expression of the iscRSUA operon YP_001724141.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001724142.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: sdy:SDY_2725 hypothetical protein YP_001724143.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_001724144.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001724145.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001724146.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: sbo:SBO_2549 [2FE-2S] ferredoxin, electron carrer protein YP_001724147.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: sdy:SDY_2720 hypothetical protein YP_001724148.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001724149.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001724150.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_001724151.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: ssn:SSON_2602 hypothetical protein YP_001724152.1 penicillin-insensitive transglycosylase/transpeptidase YP_001724153.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001724154.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001724155.1 PFAM: helix-turn-helix domain protein; KEGG: sdy:SDY_2712 hypothetical protein YP_001724156.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001724157.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001724158.1 KEGG: sdy:SDY_2709 hypothetical protein YP_001724159.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001724160.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001724161.1 PFAM: protein of unknown function DUF1407; KEGG: sdy:SDY_2706 hypothetical protein YP_001724162.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001724163.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001724164.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001724165.1 KEGG: sdy:SDY_2702 hypothetical protein YP_001724166.1 PFAM: 17 kDa surface antigen; KEGG: ssn:SSON_2587 putative outer membrane lipoprotein YP_001724167.1 PFAM: EAL domain protein; MASE1 domain protein; SMART: GGDEF domain containing protein; KEGG: ssn:SSON_2585 putative cytochrome c-type biogenesis protein YP_001724168.1 PFAM: Ppx/GppA phosphatase; KEGG: ssn:SSON_2584 exopolyphosphatase YP_001724169.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001724170.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001724171.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001724172.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001724173.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_2579 uracil transport YP_001724174.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001724175.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sdy:SDY_2684 putative oxidoreductase YP_001724176.1 PFAM: peptidase M48 Ste24p; KEGG: sfv:SFV_2539 hypothetical protein YP_001724177.1 PFAM: protein of unknown function UPF0118; KEGG: sdy:SDY_2682 putative permease YP_001724178.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon YP_001724179.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_2572 putative 2-component regulator, interaction with sigma 54 YP_001724180.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: ssn:SSON_2571 putative protein processing element YP_001724181.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ssn:SSON_2570 hydrogenase 4 Fe-S subunit YP_001724182.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_001724183.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: ssn:SSON_2568 hydrogenase 4 subunit YP_001724184.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2567 hydrogenase 4 membrane subunit YP_001724185.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_001724186.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: sfv:SFV_2529 hydrogenase 4 membrane subunit YP_001724187.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2563 hydrogenase 4 membrane subunit YP_001724188.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2526 hydrogenase 4 Fe-S subunit YP_001724189.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001724190.1 negative transcriptional regulator of the gcvTHP operon YP_001724191.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001724192.1 PFAM: NlpBDapX family lipoprotein; KEGG: ssn:SSON_2558 lipoprotein-34 YP_001724193.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001724194.1 PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: sfv:SFV_2520 hypothetical protein YP_001724195.1 PFAM: GCN5-related N-acetyltransferase; protein of unknown function DUF699 ATPase putative; KEGG: ssn:SSON_2555 hypothetical protein YP_001724196.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001724197.1 KEGG: sdy:SDY_2657 hypothetical protein YP_001724198.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001724199.1 PFAM: arsenate reductase and related; KEGG: sdy:SDY_2655 hypothetical protein YP_001724200.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: ssn:SSON_2550 AcrD YP_001724201.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sdy:SDY_2653 sensor for nitrate reductase system YP_001724202.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001724203.1 PFAM: NUDIX hydrolase; KEGG: sbo:SBO_2483 hypothetical protein YP_001724204.1 PFAM: protein of unknown function DUF1176; KEGG: sbo:SBO_2482 hypothetical protein YP_001724205.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001724206.1 KEGG: ssn:SSON_2544 transaldolase A; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001724207.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001724208.1 PFAM: microcompartments protein; KEGG: sfv:SFV_2506 hypothetical protein YP_001724209.1 TIGRFAM: ethanolamine utilization protein, EutP; KEGG: sbo:SBO_2476 hypothetical protein YP_001724210.1 PFAM: protein of unknown function DUF861 cupin_3; Ethanolamine utilisation EutQ family protein; KEGG: ssn:SSON_2540 hypothetical protein YP_001724211.1 PFAM: cobalamin adenosyltransferase; KEGG: sbo:SBO_2474 hypothetical protein YP_001724212.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_001724213.1 PFAM: microcompartments protein; KEGG: sbo:SBO_2472 detox protein YP_001724214.1 PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: sbo:SBO_2471 detox protein YP_001724215.1 PFAM: Aldehyde Dehydrogenase_; KEGG: sbo:SBO_2470 ethanolamine utilization YP_001724216.1 TIGRFAM: ethanolamine utilization protein EutJ family protein; KEGG: sbo:SBO_2469 ethanolamine utilization YP_001724217.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2533 EutG YP_001724218.1 PFAM: Ethanolamine utilisation protein EutH; KEGG: ssn:SSON_2532 EutH YP_001724219.1 ethanolamine utilization protein EutA YP_001724220.1 KEGG: shw:Sputw3181_2459 DNA-binding protein YP_001724223.1 KEGG: esa:ESA_02313 hypothetical protein YP_001724224.1 KEGG: sfv:SFV_2497 hypothetical protein YP_001724225.1 KEGG: sfx:S2646 hypothetical protein YP_001724226.1 KEGG: sfv:SFV_2496 hypothetical protein YP_001724227.1 KEGG: sfv:SFV_2495 hypothetical protein YP_001724228.1 PFAM: HNH endonuclease; KEGG: sfx:S2643 hypothetical protein YP_001724230.1 PFAM: integrase family protein; KEGG: ypp:YPDSF_3775 phage integrase YP_001724231.1 PFAM: Ethanolamine ammonia lyase large subunit; KEGG: stm:STM2458 ethanolamine ammonia-lyase, heavy chain YP_001724232.1 catalyzes the formation of acetaldehyde from ethanolamine YP_001724233.1 PFAM: microcompartments protein; KEGG: sbo:SBO_2464 hypothetical protein YP_001724234.1 PFAM: microcompartments protein; KEGG: sdy:SDY_2636 hypothetical protein YP_001724235.1 activates the transcription of the ethanolamine utilization operon YP_001724236.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001724237.1 PFAM: cell wall hydrolase/autolysin; KEGG: sbo:SBO_2460 N-acetylmuramoyl-L-alanine amidase I YP_001724238.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_2632 hypothetical protein YP_001724239.1 KEGG: ssn:SSON_2522 hypothetical protein YP_001724240.1 PFAM: protein of unknown function DUF1131; KEGG: ssn:SSON_2521 hypothetical protein YP_001724241.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbo:SBO_2456 hypothetical protein YP_001724242.1 PFAM: beta-lactamase; KEGG: ssn:SSON_2519 putative beta-lactamase YP_001724243.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_001724244.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001724245.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ssn:SSON_2516 hypothetical protein YP_001724246.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbo:SBO_2451 putative oxidoreductase YP_001724247.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_2450 thiosulfate binding protein YP_001724248.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_2449 sulfate, thiosulfate transport system permease T protein YP_001724249.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001724250.1 KEGG: sbo:SBO_2447 ATP-binding component of sulfate permease A protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001724251.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001724252.1 KEGG: sbo:SBO_2445 hypothetical protein YP_001724253.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001724254.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001724255.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001724256.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: stm:STM2431 PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase YP_001724257.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001724258.1 putative role in sulfur assimilation YP_001724259.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001724260.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001724261.1 KEGG: sdy:SDY_2607 Z3676 gene product YP_001724262.1 PFAM: Bile acid:sodium symporter; KEGG: ssn:SSON_2498 putative cytochrome oxidase YP_001724263.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2432 putative transcriptional regulator LysR-type YP_001724264.1 KEGG: sfv:SFV_2459 hypothetical protein YP_001724265.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001724266.1 PFAM: protein of unknown function DUF1323; KEGG: sbo:SBO_2425 hypothetical protein YP_001724267.1 PFAM: protein of unknown function DUF1323; KEGG: sdy:SDY_2596 hypothetical protein YP_001724268.1 PFAM: GGDEF domain containing protein; EAL domain protein; MASE1 domain protein; KEGG: sbo:SBO_2421 hypothetical protein YP_001724269.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1 YP_001724270.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sdy:SDY_2593 permease of transport system for 3 nucleosides YP_001724271.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: sbo:SBO_2417 putative transport system permease YP_001724272.1 KEGG: sbo:SBO_2416 hypothetical protein YP_001724273.1 PFAM: Chloride channel core; KEGG: sfv:SFV_2447 hypothetical protein YP_001724274.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001724275.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; KEGG: sbo:SBO_2413 putative PTS system enzyme IIB component YP_001724276.1 TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: ssn:SSON_2478 putative transport protein YP_001724277.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase YP_001724278.1 metalloprotein YP_001724279.1 TIGRFAM: PTS system, fructose subfamily, IIA subunit; phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: sfv:SFV_2441 putative PTS system enzyme IIA component, enzyme I YP_001724280.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_2474 putative AraC-type regulatory protein YP_001724281.1 PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: sbo:SBO_2407 putative 2-component transcriptional regulator YP_001724282.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: sbo:SBO_2406 putative sensor protein YP_001724283.1 PFAM: aminotransferase class I and II; KEGG: ssn:SSON_2470 putative aminotransferase YP_001724284.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001724285.1 KEGG: sdy:SDY_2575 hypothetical protein YP_001724286.1 KEGG: ssn:SSON_2467 hypothetical protein YP_001724287.1 KEGG: sdy:SDY_2573 hypothetical protein YP_001724288.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA YP_001724289.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_001724290.1 member of the AEC family of auxin efflux transporters; unknown function YP_001724291.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sbo:SBO_2397 putative enzyme YP_001724292.1 PFAM: extracellular solute-binding protein family 3; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: sfv:SFV_2429 putative sensor for regulator EvgA YP_001724293.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_001724294.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_2394 multidrug resistance protein K YP_001724295.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2393 multidrug resistance protein Y YP_001724296.1 catalyzes the formation of pyruvate from serine YP_001724297.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001724298.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001724299.1 KEGG: sdy:SDY_2551 putative transport YP_001724300.1 PFAM: VacJ family lipoprotein; KEGG: sdy:SDY_2550 lipoprotein precursor YP_001724301.1 KEGG: sfx:S2558 hypothetical protein YP_001724302.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: ssn:SSON_2400 transport of long-chain fatty acids; sensitivity to phage T2 YP_001724303.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2381 hypothetical protein YP_001724304.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001724305.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001724306.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: sbo:SBO_2378 hypothetical protein YP_001724307.1 PFAM: Fimbrial protein; KEGG: sfx:S2550 putative fimbrial-like protein YP_001724308.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sbo:SBO_2376 PapC-like porin protein YP_001724309.1 PFAM: pili assembly chaperone; KEGG: sbo:SBO_2375 putative chaperone YP_001724310.1 KEGG: sbo:SBO_2374 putative fimbrial protein YP_001724311.1 KEGG: sbo:SBO_2373 hypothetical protein YP_001724312.1 PFAM: Fimbrial protein; KEGG: sbo:SBO_2372 putative fimbrial-like protein YP_001724313.1 KEGG: sbo:SBO_2369 hypothetical protein YP_001724314.1 PFAM: Smr protein/MutS2; KEGG: sbo:SBO_2367 hypothetical protein YP_001724315.1 involved in methylation of ribosomal protein L3 YP_001724316.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001724317.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001724318.1 PFAM: protein of unknown function DUF81; KEGG: ssn:SSON_2385 putative structural protein YP_001724319.1 PFAM: protein of unknown function DUF462; KEGG: sfx:S2537 putative transporting ATPase YP_001724320.1 PFAM: YfcL protein; KEGG: sdy:SDY_2524 hypothetical protein YP_001724321.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001724322.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001724323.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2380 putative transport protein YP_001724324.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001724325.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_2378 erythronate-4-phosphate dehyrogenase YP_001724326.1 PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: sdy:SDY_2518 putative PTS system enzyme II A component YP_001724327.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001724328.1 PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_2386 hypothetical protein YP_001724329.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001724330.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_2352 dihydrofolate:folylpolyglutamate synthetase YP_001724331.1 PFAM: Sporulation domain protein; KEGG: sbo:SBO_2351 putative lipoprotein YP_001724332.1 membrane protein required for colicin V production YP_001724333.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001724334.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001724335.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: ssn:SSON_2368 lysine-, arginine-, ornithine-binding periplasmic protein YP_001724336.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: sbo:SBO_2346 histidine-binding periplasmic protein of high-affinity histidine transport system YP_001724337.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_2507 histidine transport system permease protein YP_001724338.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_2506 histidine transport, membrane protein M YP_001724339.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_2364 ATP-binding component of histidine transport YP_001724340.1 PFAM: putative transposase YhgA family protein; KEGG: sfv:SFV_2372 hypothetical protein YP_001724341.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; domain of unknown function DUF1731; KEGG: sbo:SBO_2339 putative sugar nucleotide epimerase YP_001724342.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001724343.1 PFAM: Glutathione S-transferase domain; KEGG: ssn:SSON_2359 putative S-transferase YP_001724344.1 PFAM: Glutathione S-transferase domain; KEGG: sfv:SFV_2368 hypothetical protein YP_001724345.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: sbo:SBO_2335 hypothetical protein YP_001724346.1 PFAM: NUDIX hydrolase; KEGG: sbo:SBO_2334 putative regulator YP_001724347.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: ssn:SSON_2355 putative S-transferase YP_001724348.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001724349.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001724350.1 PFAM: protein of unknown function DUF412; KEGG: sdy:SDY_2491 hypothetical protein YP_001724351.1 PFAM: YfbU family protein; KEGG: sdy:SDY_2490 hypothetical protein YP_001724352.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfv:SFV_2360 putative phosphatase YP_001724353.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ssn:SSON_2349 putative transport protein YP_001724354.1 KEGG: sfv:SFV_2358 putative alpha helix protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_001724355.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001724356.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2322 NADH dehydrogenase transcriptional regulator YP_001724357.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724358.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001724359.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001724360.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724361.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001724362.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724363.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724364.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724365.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724366.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724367.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001724368.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724369.1 Catalyzes the transfer of electrons from NADH to quinone YP_001724370.1 PFAM: Domain of unknown function DUF1877; KEGG: sdy:SDY_2471 hypothetical protein YP_001724371.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001724372.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_2338 hypothetical protein YP_001724373.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2462 hypothetical protein YP_001724374.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: sfv:SFV_2336 isochorismate hydroxymutase 2 YP_001724375.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001724376.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_001724377.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001724378.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001724379.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: sdy:SDY_2456 O-succinylbenzoate-CoA ligase YP_001724380.1 KEGG: ssn:SSON_2320 polymyxin resistance protein B YP_001724381.1 KEGG: sbo:SBO_2295 putative transport/receptor protein YP_001724382.1 PFAM: small multidrug resistance protein; KEGG: sfx:S2567 sucrose-6 phosphate hydrolase YP_001724383.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001724384.1 PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_2317 hypothetical protein YP_001724385.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001724386.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001724387.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001724388.1 PFAM: Phosphoglycerate mutase; KEGG: ssn:SSON_2313 protein induced by aluminum YP_001724389.1 PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2321 hypothetical protein YP_001724390.1 PFAM: YfaZ family protein; KEGG: ssn:SSON_2311 hypothetical protein YP_001724391.1 TIGRFAM: molybdenum cofactor synthesis domain protein; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: sfx:S2461 competence/damage-inducible protein CinA YP_001724392.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ssn:SSON_2309 putative regulator YP_001724393.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sbo:SBO_2047 putative racemase YP_001724394.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2048 putative transport protein YP_001724395.1 PFAM: HpcH/HpaI aldolase; KEGG: ssn:SSON_2306 hypothetical protein YP_001724396.1 PFAM: putative transposase YhgA family protein; KEGG: sbo:SBO_2050 hypothetical protein YP_001724398.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_001724399.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_001724400.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_001724401.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_001724402.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_001724403.1 KEGG: sbo:SBO_2056 hypothetical protein YP_001724404.1 PFAM: lipopolysaccharide kinase; KEGG: sfv:SFV_2310 pH-inducible protein involved in stress response YP_001724405.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001724406.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001724407.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001724408.1 TIGRFAM: polymorphic outer membrane protein; outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Polymorphic membrane protein Chlamydia; Pertactin; Autotransporter beta- domain protein; KEGG: sdy:SDY_2425 putative ATP-binding component of a transport system YP_001724409.1 Involved in ubiquinone biosynthesis YP_001724410.1 negatively supercoils closed circular double-stranded DNA YP_001724411.1 KEGG: ssn:SSON_2288 hypothetical protein YP_001724412.1 PFAM: protein of unknown function DUF1175; KEGG: sfv:SFV_2299 hypothetical protein YP_001724413.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: sdy:SDY_0852 large extracellular alpha-helical protein YP_001724414.1 KEGG: ssn:SSON_2285 hypothetical protein YP_001724415.1 KEGG: sfv:SFV_2294 hypothetical protein YP_001724416.1 KEGG: ssn:SSON_2283 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001724417.1 PFAM: short chain fatty acid transporter; KEGG: ssn:SSON_2282 short chain fatty acid transporter YP_001724418.1 KEGG: ssn:SSON_2281 acetyl-CoA:acetoacetyl-CoA transferase beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001724419.1 KEGG: ssn:SSON_2280 acetyl-CoA:acetoacetyl-CoA transferase alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001724420.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_001724421.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_001724422.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase; KEGG: sfx:S2433 sensor for ctr capsule biosynthesis, probable histidine kinase acting on RcsB YP_001724423.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001724424.1 PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: sbo:SBO_2091 putative 2-component sensor protein YP_001724425.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_001724426.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_001724427.1 KEGG: sbo:SBO_2094 O6-methylguanine-DNA methyltransferase; transcription activator/repressor; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding YP_001724428.1 TIGRFAM: alkylated DNA repair protein AlkB; PFAM: 2OG-Fe(II) oxygenase; KEGG: sbo:SBO_2095 AlkB YP_001724429.1 efflux pump for the antibacterial peptide microcin J25 YP_001724430.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001724431.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001724432.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. YP_001724433.1 PFAM: NapD family protein; KEGG: sbo:SBO_2100 hypothetical protein YP_001724434.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001724435.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001724436.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001724437.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_001724438.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_001724439.1 ATP-binding protein; required for proper cytochrome c maturation YP_001724440.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: sdy:SDY_0878 heme exporter protein B YP_001724441.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: sdy:SDY_0879 heme exporter protein C YP_001724442.1 TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: sdy:SDY_0880 heme exporter protein C YP_001724443.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001724444.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: sbo:SBO_2111 cytochrome c-type biogenesis protein YP_001724445.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sbo:SBO_2112 disulfide oxidoreductase YP_001724446.1 PFAM: cytochrome C biogenesis protein; KEGG: sfv:SFV_2270 possible subunit of heme lyase YP_001724447.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_001724448.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfv:SFV_2268 putative ATP-binding component of a transport system YP_001724449.1 PFAM: sulfatase; KEGG: ssn:SSON_2244 putative sulfatase YP_001724450.1 PFAM: protein of unknown function DUF1414; KEGG: sbo:SBO_2137 hypothetical protein YP_001724451.1 PFAM: 37kDa nucleoid-associated protein; KEGG: sdy:SDY_0893 hypothetical protein YP_001724452.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001724453.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sdy:SDY_0895 putative ATP-dependent helicase YP_001724454.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001724455.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001724456.1 KEGG: sdy:SDY_0898 hypothetical protein YP_001724457.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_0899 putative ATP-binding component of a transport system YP_001724458.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_2145 putative transport system permease protein YP_001724459.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2234 putative transport system permease protein YP_001724460.1 PFAM: extracellular solute-binding protein family 5; KEGG: sdy:SDY_0902 hypothetical protein YP_001724461.1 PFAM: EAL domain protein; KEGG: sdy:SDY_0903 hypothetical protein YP_001724462.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001724463.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_2230 hypothetical protein YP_001724464.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sfx:S2389 hypothetical protein YP_001724465.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ssn:SSON_2228 putative oxidoreductase YP_001724466.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_001724467.1 PFAM: protein of unknown function UPF0153; KEGG: ent:Ent638_2765 protein of unknown function UPF0153 YP_001724468.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2226 putative transport YP_001724469.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001724470.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001724471.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001724472.1 PFAM: PfkB domain protein; KEGG: sfv:SFV_2241 putative kinase YP_001724473.1 PFAM: Indigoidine synthase A family protein; KEGG: sfv:SFV_2240 hypothetical protein YP_001724474.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sfv:SFV_2239 putative transport system permease protein YP_001724475.1 activator of nucleoside metabolism YP_001724476.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively YP_001724477.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_2167 putative kinase YP_001724478.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001724479.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2169 hypothetical protein YP_001724480.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_2213 putative transcriptional regulator LysR-type YP_001724481.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2110 lysine-specific permease YP_001724482.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_001724483.1 KEGG: sbo:SBO_2173 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_001724484.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001724485.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: sbo:SBO_2175 hypothetical protein YP_001724486.1 negative regulator of the mglBAC operon for galactose utilization YP_001724487.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sdy:SDY_2130 galactose-binding transport protein YP_001724488.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001724489.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001724490.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001724491.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001724492.1 KEGG: sbo:SBO_0996 hypothetical protein YP_001724493.1 PFAM: protein of unknown function DUF218; KEGG: sdy:SDY_2143 vancomycin sensitivity YP_001724494.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001724495.1 PFAM: LrgB family protein; KEGG: ssn:SSON_2198 putative seritonin transporter YP_001724496.1 PFAM: LrgA family protein; KEGG: sbo:SBO_1000 hypothetical protein YP_001724497.1 PFAM: dihydrouridine synthase DuS; KEGG: ssn:SSON_2196 putative regulator protein YP_001724498.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001724499.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbo:SBO_1007 putative oxidoreductase YP_001724500.1 PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_1008 hypothetical protein YP_001724501.1 PFAM: protein of unknown function DUF1282; KEGG: sbo:SBO_1009 hypothetical protein YP_001724502.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001724503.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001724504.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: ssn:SSON_2189 beta-D-glucoside glucohydrolase, periplasmic YP_001724505.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ssn:SSON_2188 putative transport system permease protein YP_001724506.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2187 putative transport system permease protein YP_001724507.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_2186 putative ATP-binding component of a transport system YP_001724508.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2185 putative transport system permease protein YP_001724509.1 PFAM: regulatory protein MerR; KEGG: sdy:SDY_2162 putative transcriptional regulator YP_001724510.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: sfx:S2325 putative 2-component sensor protein YP_001724511.1 unknown function; when overproduced it confers drug-resistance YP_001724512.1 PFAM: protein of unknown function DUF1456; KEGG: sdy:SDY_2165 hypothetical protein YP_001724513.1 PFAM: protein of unknown function DUF1307; KEGG: ssn:SSON_2169 hypothetical protein YP_001724514.1 PFAM: zinc finger SWIM domain protein; KEGG: sfx:S2316 hypothetical protein YP_001724515.1 KEGG: sfl:SF2189 hypothetical protein YP_001724516.1 PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sfx:S2313 hypothetical protein YP_001724517.1 KEGG: sfl:SF2187 hypothetical protein YP_001724518.1 KEGG: sbo:SBO_0938 putative regulator YP_001724519.1 PFAM: WGR domain protein; KEGG: sbo:SBO_0937 putative regulator (fragment) YP_001724520.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001724521.1 KEGG: sfv:SFV_2169 putative ATPase YP_001724522.1 KEGG: ssn:SSON_2161 hypothetical protein YP_001724523.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_2160 putative fimbrial-like protein YP_001724524.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_2159 putative chaperone YP_001724525.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfv:SFV_2164 putative outer membrane protein YP_001724526.1 KEGG: ssn:SSON_2156 putative type-1 fimbrial protein YP_001724527.1 KEGG: ssn:SSON_2155 hypothetical protein YP_001724528.1 membrane protein conferring nickel and cobalt resistance YP_001724529.1 PFAM: protein of unknown function DUF156; KEGG: sdy:SDY_2279 hypothetical protein YP_001724530.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_001724531.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001724532.1 PFAM: glycoside hydrolase family 25; KEGG: sbo:SBO_0923 hypothetical protein YP_001724533.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sdy:SDY_2274 putative transcriptional regulator YP_001724534.1 PFAM: ADP-ribosylation/Crystallin J1; KEGG: ssn:SSON_2147 hypothetical protein YP_001724535.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_2146 putative nucleoside permease protein YP_001724536.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001724537.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001724538.1 KEGG: sfv:SFV_2150 putative tagatose 6-phosphate kinase 1; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ YP_001724539.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001724540.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001724541.1 TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: ssn:SSON_2139 PTS system galactitol-specific enzyme IIC YP_001724542.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_001724543.1 PFAM: regulatory protein DeoR; KEGG: ssn:SSON_2137 galactitol utilization operon repressor YP_001724544.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001724545.1 KEGG: sbo:SBO_0909 hypothetical protein YP_001724546.1 PFAM: peptidase U32; KEGG: ssn:SSON_2134 hypothetical protein YP_001724547.1 PFAM: protein of unknown function DUF1508; KEGG: sbo:SBO_0906 hypothetical protein YP_001724548.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001724549.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sfv:SFV_2139 sensor protein (for BaeR) YP_001724550.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S2267 putative transport protein YP_001724551.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001724552.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001724553.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001724554.1 PFAM: von Willebrand factor type A; KEGG: sbo:SBO_0899 hypothetical protein YP_001724555.1 KEGG: ssn:SSON_2124 hypothetical protein YP_001724556.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001724557.1 KEGG: ssn:SSON_2123 putative chaperonin YP_001724558.1 KEGG: sbo:SBO_0896 putative heat shock protein YP_001724559.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_001724560.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction YP_001724561.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001724562.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001724563.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001724564.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: sfv:SFV_2122 putative transport protein YP_001724565.1 PFAM: polysaccharide export protein; KEGG: ssn:SSON_2115 putative polysaccharide export protein YP_001724566.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis YP_001724567.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_001724568.1 PFAM: glycosyl transferase family 2; KEGG: sbo:SBO_0886 putative regulator YP_001724569.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium YP_001724570.1 KEGG: sbo:SBO_0884 putative glycosyl transferase YP_001724571.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_001724572.1 PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_2108 putative colanic acid biosynthesis glycosyl transferase YP_001724573.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_001724574.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_0880 GDP-D-mannose dehydratase YP_001724575.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_0879 putative nucleotide di-P-sugar epimerase YP_001724576.1 PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2108 GDP-mannose mannosyl hydrolase YP_001724577.1 PFAM: glycosyl transferase group 1; KEGG: sfx:S2236 putative colanic biosynthesis glycosyl transferase YP_001724578.1 KEGG: ssn:SSON_2102 mannose-1-phosphate guanyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein YP_001724579.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sbo:SBO_0875 phosphomannomutase YP_001724580.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_001724581.1 PFAM: polysaccharide biosynthesis protein; KEGG: sbo:SBO_0873 probable export protein YP_001724582.1 PFAM: polysaccharide pyruvyl transferase; KEGG: sbo:SBO_0872 putative galactokinase YP_001724583.1 PFAM: glycosyl transferase group 1; KEGG: sbo:SBO_0871 putative colanic acid biosynthesis glycosyl transferase YP_001724584.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_001724585.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: esa:ESA_01176 hypothetical protein YP_001724586.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001724587.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001724588.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose YP_001724589.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sbo:SBO_0866 glucose-1-phosphate thymidylyltransferase YP_001724590.1 KEGG: sdy:SDY_2207 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001724591.1 PFAM: nitroreductase; KEGG: mpt:Mpe_A0731 nitroreductase-like protein YP_001724592.1 KEGG: bfs:BF2791 putative transmembrane protein YP_001724593.1 KEGG: bfs:BF2794 hypothetical protein YP_001724594.1 PFAM: glycosyl transferase group 1; KEGG: lsl:LSL_0978 glycosyltransferase YP_001724595.1 KEGG: ssp:SSP0069 putative polysaccharide polymerase YP_001724596.1 PFAM: glycosyl transferase family 2; KEGG: pat:Patl_3205 rhamnosyltransferase YP_001724597.1 PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein YP_001724598.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001724599.1 KEGG: ssn:SSON_2099 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase YP_001724600.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: ssn:SSON_2098 regulator of length of O-antigen component of lipopolysaccharide chains YP_001724601.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001724602.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001724603.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001724604.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001724605.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001724606.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001724607.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001724608.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001724609.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ssn:SSON_2086 putative enzyme of sugar metabolism YP_001724610.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_0841 putative transcriptional regulator LysR-type YP_001724611.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2226 putative amino acid/amine transport protein YP_001724612.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: ssn:SSON_2083 putative transport system permease protein YP_001724613.1 PFAM: SirA family protein; KEGG: sbo:SBO_0836 hypothetical protein YP_001724614.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001724615.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001724616.1 PFAM: transcription activator effector binding; KEGG: ssn:SSON_2079 SbmC protein YP_001724617.1 KEGG: ssn:SSON_2078 hypothetical protein YP_001724618.1 PFAM: protein of unknown function DUF496; KEGG: sbo:SBO_0832 putative alpha helix protein YP_001724619.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001724620.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001724621.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001724622.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2243 hypothetical protein YP_001724623.1 PFAM: putative sugar-binding domain protein; KEGG: sco:SCO1463 putative transcriptional regulator YP_001724624.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: lca:LSEI_2707 phosphotransferase system galactitol-specific IIA domain (Ntr-type) YP_001724625.1 KEGG: sak:SAK_0530 PTS system, galactitol-specific IIB component, putative YP_001724626.1 PFAM: PTS system Galactitol-specific IIC component; KEGG: tte:TTE0183 PTS system, galactitol-specific IIC component YP_001724627.1 TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: aae:aq_1138 ribose 5-phosphate isomerase B YP_001724628.1 PFAM: regulatory protein DeoR; KEGG: bcl:ABC3573 transcriptional regulator, DeoR family YP_001724629.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: hso:HS_1144 PTS system, galactitol-specific IIA component YP_001724630.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: cdf:CD1083 PTS system, IIb component YP_001724631.1 PFAM: PTS system Galactitol-specific IIC component; KEGG: pac:PPA0022 PTS system, galactitol-specific IIC component YP_001724632.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: lmf:LMOf2365_0534 ribulose-phosphate 3-epimerase YP_001724633.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpu:BPUM_1176 short chain dehydrogenase YP_001724634.1 PFAM: sugar isomerase (SIS); KEGG: bsu:BG11182 6-phospho-3-hexuloisomerase YP_001724636.1 KEGG: plu:plu0532 hypothetical protein YP_001724637.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001724638.1 KEGG: sbo:SBO_1138 hypothetical protein YP_001724639.1 KEGG: ypk:y3085 hypothetical protein YP_001724640.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_001724641.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_001724642.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ssn:SSON_2044 hypothetical protein YP_001724643.1 PFAM: protein of unknown function DUF28; KEGG: sbo:SBO_1217 hypothetical protein YP_001724644.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001724645.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2254 putative transport protein, shikimate YP_001724646.1 KEGG: ssn:SSON_2040 hypothetical protein YP_001724647.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001724648.1 KEGG: ypk:y3085 hypothetical protein YP_001724649.1 PFAM: protein of unknown function DUF980; KEGG: ssn:SSON_2035 hypothetical protein YP_001724650.1 PFAM: cytochrome B561; KEGG: sbo:SBO_1032 putative cytochrome YP_001724651.1 PFAM: YodA domain protein; KEGG: sdy:SDY_1033 hypothetical protein YP_001724652.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001724653.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001724654.1 TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: sfv:SFV_2015 hypothetical protein YP_001724655.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_001724656.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_2026 putative 2-component sensor protein YP_001724657.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_001724658.1 PFAM: porin Gram-negative type; KEGG: spe:Spro_1730 porin gram-negative type YP_001724659.1 KEGG: sbo:SBO_1045 hypothetical protein YP_001724660.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbo:SBO_1046 hypothetical protein YP_001724661.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ssn:SSON_2018 DNA cytosine methylase YP_001724662.1 TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: sdy:SDY_1046 DNA mismatch endonuclease, patch repair protein YP_001724663.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_1049 putative transmembrane subunit YP_001724664.1 PFAM: protein of unknown function DUF808; KEGG: sdy:SDY_1048 hypothetical protein YP_001724665.1 KEGG: sdy:SDY_1049 hypothetical protein YP_001724666.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_2013 hypothetical protein YP_001724667.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001724668.1 KEGG: sdy:SDY_1052 hypothetical protein YP_001724669.1 KEGG: sdy:SDY_1053 hypothetical protein YP_001724670.1 PFAM: regulatory protein LuxR; KEGG: sbo:SBO_1056 positive regulator for ctr capsule biosynthesis, positive transcription factor YP_001724671.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001724672.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001724673.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001724674.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus YP_001724675.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001724676.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001724677.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001724678.1 PFAM: flagellar hook-length control protein; KEGG: sfv:SFV_1986 flagellar hook-length control protein YP_001724679.1 rod/hook and filament chaperone YP_001724680.1 involved in type III protein export during flagellum assembly YP_001724681.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001724682.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001724683.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001724684.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001724685.1 PFAM: protein of unknown function DUF159; KEGG: sdy:SDY_1084 hypothetical protein YP_001724686.1 PFAM: SirA family protein; KEGG: cko:CKO_01008 hypothetical protein YP_001724687.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: sbo:SBO_1077 putative transport system permease protein YP_001724688.1 KEGG: sdy:SDY_1087 hypothetical protein YP_001724689.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001724690.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001724691.1 flagellin specific chaperone YP_001724692.1 involved in flagellin assembly YP_001724693.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes YP_001724694.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001724695.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_001724696.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: sfl:SF1963 putative periplasmic binding transport protein YP_001724697.1 catalyzes the formation of pyruvate from D-cysteine YP_001724698.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1200 putative transport system permease protein (former YecC) YP_001724699.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_1201 putative ATP-binding component of a transport system YP_001724700.1 regulates genes involved in cell division YP_001724701.1 KEGG: sdy:SDY_1103 hypothetical protein YP_001724702.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001724703.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001724704.1 KEGG: sdy:SDY_1106 phosphatidylglycerophosphate synthetase CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyl transferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001724705.1 TIGRFAM: yecA family protein; PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1098 hypothetical protein YP_001724706.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ssn:SSON_1211 tyrosine-specific transport system YP_001724707.1 KEGG: sfv:SFV_1950 hypothetical protein YP_001724708.1 cytoplasmic iron storage protein YP_001724709.1 KEGG: sdy:SDY_1114 hypothetical protein YP_001724710.1 PFAM: Ferritin Dps family protein; KEGG: sdy:SDY_1116 ferritin-like protein YP_001724711.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ssn:SSON_1217 L-arabinose-binding periplasmic protein YP_001724712.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001724713.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001724714.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_001724715.1 KEGG: sdy:SDY_1193 trehalose-6-phosphate synthase; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; PFAM: glycosyl transferase family 20 YP_001724716.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001724717.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001724718.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001724719.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001724720.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001724721.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001724722.1 PFAM: CheW domain protein; KEGG: ssn:SSON_1230 positive regulator of CheA protein activity YP_001724723.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ssn:SSON_1231 methyl-accepting chemotaxis protein II YP_001724724.1 mediates taxis toward dipeptides YP_001724725.1 methylates the MCP YP_001724726.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001724727.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001724728.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001724729.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001724730.1 membrane protein involved in the flagellar export apparatus YP_001724731.1 PFAM: flagellar FlhE family protein; KEGG: sbo:SBO_1122 flagellar protein YP_001724732.1 PFAM: protein of unknown function DUF1311; KEGG: sbo:SBO_1123 hypothetical protein YP_001724733.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001724734.1 PFAM: protein of unknown function DUF991; KEGG: sdy:SDY_1179 hypothetical protein YP_001724735.1 PFAM: CutC family protein; KEGG: sbo:SBO_1126 copper homeostasis protein YP_001724736.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: sfv:SFV_1911 putative cytochrome c-type protein YP_001724737.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfx:S2003 biotin sulfoxide reductase 2 YP_001724738.1 TIGRFAM: methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; KEGG: sdy:SDY_1170 putative enzyme YP_001724739.1 TIGRFAM: methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdy:SDY_1169 hypothetical protein YP_001724740.1 KEGG: sdy:SDY_1168 hypothetical protein YP_001724741.1 PFAM: protein of unknown function DUF72; KEGG: stm:STM1903 putative cytoplasmic protein YP_001724742.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1274 hypothetical protein YP_001724743.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001724744.1 converts dATP to dAMP and pyrophosphate YP_001724745.1 PFAM: protein of unknown function DUF28; KEGG: ssn:SSON_1277 hypothetical protein YP_001724746.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001724747.1 PFAM: protein of unknown function DUF1105; KEGG: ssn:SSON_1279 hypothetical protein YP_001724748.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001724749.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001724750.1 involved in transport of zinc(II) with ZnuA and C YP_001724751.1 involved in transport of zinc(II) with ZnuA and C YP_001724752.1 involved in transport of zinc(II) with ZnuA and C YP_001724753.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sbo:SBO_1173 hypothetical protein YP_001724754.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001724755.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001724756.1 Represses the expression of the zwf, eda, glp and gap YP_001724757.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001724758.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001724759.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001724760.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001724761.1 PFAM: YebG family protein; KEGG: sdy:SDY_1134 hypothetical protein YP_001724762.1 secreted protein; unknown function YP_001724763.1 PFAM: protein of unknown function DUF533; KEGG: sdy:SDY_1132 hypothetical protein YP_001724764.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_001724765.1 3'-5' exonuclease activity on single or double-strand DNA YP_001724766.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ssn:SSON_1305 hypothetical protein YP_001724767.1 PFAM: DNA polymerase II beta subunit; KEGG: sdy:SDY_1128 DNA polymerase III, theta subunit YP_001724768.1 PFAM: copper resistance protein CopC; KEGG: sbo:SBO_1145 hypothetical protein YP_001724769.1 PFAM: copper resistance D domain protein; KEGG: ssn:SSON_1308 putative resistance protein YP_001724770.1 KEGG: sdy:SDY_1125 hypothetical protein YP_001724771.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_001724772.1 PFAM: protein of unknown function DUF1482; KEGG: sdy:SDY_1988 hypothetical protein YP_001724773.1 PFAM: protein of unknown function DUF1480; KEGG: sdy:SDY_1987 hypothetical protein YP_001724774.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001724775.1 PFAM: Mammalian cell entry related domain protein; KEGG: ssn:SSON_1327 hypothetical protein YP_001724776.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: ssn:SSON_1328 hypothetical protein YP_001724777.1 PFAM: GAF domain protein; KEGG: sdy:SDY_1980 hypothetical protein YP_001724778.1 affects solute and DNA transport through an unknown mechanism YP_001724779.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001724780.1 putative metalloprotease YP_001724781.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1241 putative transport protein YP_001724782.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sbo:SBO_1240 putative regulator YP_001724783.1 KEGG: sdy:SDY_1974 hypothetical protein YP_001724784.1 KEGG: sdy:SDY_1973 hypothetical protein YP_001724785.1 KEGG: sbo:SBO_1238 hypothetical protein YP_001724786.1 KEGG: cko:CKO_01153 hypothetical protein YP_001724787.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001724788.1 membrane protein YebN YP_001724789.1 PFAM: protein of unknown function DUF986; KEGG: sdy:SDY_1966 hypothetical protein YP_001724790.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_001724791.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sbo:SBO_1230 PTS enzyme IIC, mannose-specific YP_001724792.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001724793.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: sbo:SBO_1228 putative transport protein YP_001724794.1 PFAM: EAL domain protein; KEGG: ssn:SSON_1345 hypothetical protein YP_001724795.1 KEGG: sbo:SBO_1270 L-serine deaminase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001724796.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1719 hypothetical protein YP_001724797.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: ssn:SSON_1348 p-aminobenzoate synthetase, component I YP_001724798.1 PFAM: protein of unknown function UPF0181; KEGG: sdy:SDY_1717 hypothetical protein YP_001724799.1 PFAM: Domain of unknown function DUF1889; KEGG: sbo:SBO_1276 hypothetical protein YP_001724800.1 PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_1713 hypothetical protein YP_001724801.1 SMART: helicase c2; DEAD-like helicases; KEGG: sbo:SBO_1280 putative enzyme YP_001724802.1 PFAM: peptidase M22 glycoprotease; KEGG: sfv:SFV_1422 hypothetical protein YP_001724803.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sfv:SFV_1423 putative outer membrane protein YP_001724804.1 Activates fatty acids by binding to coenzyme A YP_001724805.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: sfv:SFV_1425 RNase D, processes tRNA precursor YP_001724806.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ssn:SSON_1358 putative diogenase beta subunit YP_001724807.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_1359 hypothetical protein YP_001724808.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001724809.1 KEGG: ssn:SSON_1361 putative tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_001724810.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1289 putative transcriptional regulator LysR-type YP_001724811.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sdy:SDY_1698 hypothetical protein YP_001724812.1 PFAM: Protein of unknown function DUF1971; KEGG: sdy:SDY_1697 hypothetical protein YP_001724813.1 PFAM: Domain of unknown function DUF1869; KEGG: sdy:SDY_1696 hypothetical protein YP_001724814.1 PFAM: Transglycosylase-associated protein; KEGG: sdy:SDY_1695 hypothetical protein YP_001724815.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: sdy:SDY_1692 hypothetical protein YP_001724816.1 PFAM: protein of unknown function DUF333; KEGG: sfx:S1546 hypothetical protein YP_001724817.1 PFAM: protein of unknown function DUF488; KEGG: ssn:SSON_1369 hypothetical protein YP_001724818.1 TIGRFAM: cyanate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1302 putative amino acid/amine transport protein YP_001724819.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_1688 putative AraC-type regulatory protein YP_001724820.1 PFAM: protein of unknown function DUF441; KEGG: sbo:SBO_1304 hypothetical protein YP_001724821.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sbo:SBO_1306 hypothetical protein YP_001724822.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1375 hypothetical protein YP_001724823.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1377 hypothetical protein YP_001724824.1 PFAM: protein of unknown function DUF444; KEGG: sbo:SBO_1309 hypothetical protein YP_001724825.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: sbo:SBO_1310 hypothetical protein YP_001724826.1 PFAM: MltA-interacting MipA family protein; KEGG: sdy:SDY_1485 hypothetical protein YP_001724827.1 PFAM: aldo/keto reductase; KEGG: ssn:SSON_1381 putative an aldehyde reductase YP_001724828.1 PFAM: Aldose 1-epimerase; KEGG: sfv:SFV_1435 hypothetical protein YP_001724829.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: sdy:SDY_1488 glyceraldehyde-3-phosphate dehydrogenase A YP_001724830.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001724831.1 PFAM: protein of unknown function DUF1315; KEGG: sbo:SBO_1318 hypothetical protein YP_001724832.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_1491 putative oxidoreductase YP_001724833.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_1492 putative transport protein YP_001724834.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sec:SC1309 hypothetical zinc-type alcohol dehydrogenase-like YP_001724835.1 KEGG: sfx:S1565 putative aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II YP_001724836.1 PFAM: PfkB domain protein; KEGG: sfx:S1566 putative kinase YP_001724837.1 PFAM: regulatory protein DeoR; KEGG: sdy:SDY_1498 putative DeoR-type transcriptional regulator YP_001724838.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sfx:S1569 putative transport protein YP_001724839.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001724840.1 converts asparagine to aspartate and ammonia YP_001724841.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001724842.1 PFAM: nitroreductase; KEGG: sbo:SBO_1322 hypothetical protein YP_001724843.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001724844.1 decatenates replicating daughter chromosomes YP_001724845.1 KEGG: sfl:SF1461 hypothetical protein YP_001724846.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001724847.1 PFAM: protein of unknown function DUF1496; KEGG: sbo:SBO_1329 hypothetical protein YP_001724848.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1516 hypothetical protein YP_001724849.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfx:S1582 putative cytochrome oxidase YP_001724850.1 SMART: Rhodanese domain protein; KEGG: sbo:SBO_1332 putative thiosulfate sulfur transferase YP_001724851.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_1462 putative ATP-binding component of a transport system YP_001724852.1 KEGG: sdy:SDY_1520 putative transport system permease protein YP_001724853.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1403 hypothetical protein YP_001724854.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: sbo:SBO_1336 hypothetical protein YP_001724855.1 PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_1468 hypothetical protein YP_001724856.1 KEGG: ssn:SSON_1406 hypothetical protein YP_001724857.1 PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_1407 hypothetical protein YP_001724858.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001724859.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_001724860.1 KEGG: sdy:SDY_1530 hypothetical protein; TIGRFAM: arginine/ornithine succinyltransferase subunit; arginine N-succinyltransferase; PFAM: arginine N-succinyltransferase beta subunit YP_001724861.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001724862.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001724863.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001724864.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_001724865.1 PFAM: protein of unknown function DUF886; KEGG: sbo:SBO_1348 hypothetical protein YP_001724866.1 3' incision activity; acts with UvrC YP_001724867.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001724868.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001724869.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001724870.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001724871.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001724872.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_001724873.1 PFAM: glycoside hydrolase family 4; KEGG: sfx:S1611 cryptic phospho-beta-glucosidase; cryptic YP_001724874.1 PFAM: YdjC family protein; KEGG: ssn:SSON_1425 hypothetical protein YP_001724875.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_001724876.1 KEGG: ssn:SSON_1427 hypothetical protein YP_001724877.1 KEGG: sfl:SF1498 hypothetical protein YP_001724878.1 PFAM: sodium:dicarboxylate symporter; KEGG: sbo:SBO_1361 kinase fragment YP_001724879.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: sdy:SDY_1821 hypothetical protein YP_001724880.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001724881.1 KEGG: sdy:SDY_1819 hypothetical protein YP_001724882.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: sdy:SDY_1818 hypothetical protein YP_001724883.1 KEGG: sdy:SDY_1817 hypothetical protein YP_001724884.1 TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: sbo:SBO_1367 6-phosphofructokinase II YP_001724885.1 PFAM: protein of unknown function DUF481; KEGG: ssn:SSON_1435 hypothetical protein YP_001724886.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001724887.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001724888.1 PFAM: ribosomal protein L35; KEGG: kpn:KPN_02178 50S ribosomal protein L35 YP_001724889.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001724890.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001724891.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001724892.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001724893.1 with BtuD and BtuF transports vitamin B12 into the cell YP_001724894.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_001724895.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_001724896.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_1450 lipoprotein YP_001724897.1 KEGG: sbo:SBO_1421 hypothetical protein YP_001724898.1 PFAM: protein of unknown function UPF0061; KEGG: sbo:SBO_1422 hypothetical protein YP_001724899.1 KEGG: sbo:SBO_1423 hypothetical protein YP_001724900.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001724901.1 PFAM: protein of unknown function DUF299; KEGG: sdy:SDY_1797 hypothetical protein YP_001724902.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001724903.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids YP_001724904.1 KEGG: sbo:SBO_1431 hypothetical protein YP_001724905.1 PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sfv:SFV_1525 probable electron transfer flavoprotein-quinone oxidoreductase YdiS YP_001724906.1 May play a role in a redox process YP_001724907.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001724908.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; KEGG: sbo:SBO_1435 putative AraC-type regulatory protein YP_001724909.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001724910.1 PFAM: coenzyme A transferase; KEGG: stm:STM1357.S putative acetyl-CoA/acetoacetyl-CoA transferase beta subunit YP_001724911.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_001724912.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_001724913.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1463 putative amino acid/amine transport protein YP_001724914.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S1852 putative transport system permease protein YP_001724915.1 PFAM: Domain of unknown function DUF1870; KEGG: ssn:SSON_1466 hypothetical protein YP_001724916.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_001724917.1 PFAM: FAD linked oxidase domain protein; KEGG: ssn:SSON_1469 putative oxidase YP_001724918.1 PFAM: thioesterase superfamily protein; KEGG: sbo:SBO_1444 hypothetical protein YP_001724919.1 KEGG: sbo:SBO_1445 hypothetical protein YP_001724920.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_001724921.1 with SufCD activates cysteine desulfurase SufS YP_001724922.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001724923.1 with SufBC activates cysteine desulfurase SufS YP_001724924.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_001724925.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001724926.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sfv:SFV_1701 hypothetical protein YP_001724927.1 PFAM: LPP repeat-containing protein; KEGG: sdy:SDY_1908 murein lipoprotein YP_001724928.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001724929.1 KEGG: sdy:SDY_1904 hypothetical protein YP_001724930.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_1458 putative oxidoreductase, Fe-S subunit YP_001724931.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: sbo:SBO_1459 hypothetical protein YP_001724932.1 KEGG: sbo:SBO_1460 hypothetical protein YP_001724933.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1899 putative oxidoreductase, Fe-S subunit YP_001724934.1 PFAM: cytochrome B561; KEGG: sbo:SBO_1462 hypothetical protein YP_001724935.1 KEGG: ssn:SSON_1487 hypothetical protein YP_001724936.1 KEGG: sbo:SBO_1464 hypothetical protein YP_001724937.1 PFAM: Putative mono-oxygenase ydhR; KEGG: sbo:SBO_1465 hypothetical protein YP_001724938.1 KEGG: sdy:SDY_1891 possible enzyme YP_001724939.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001724940.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001724941.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001724942.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001724943.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1472 putative transcriptional regulator LysR-type YP_001724944.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001724945.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_1883 putative transport protein YP_001724946.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_001724947.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_1501 putative lipoprotein YP_001724948.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sdy:SDY_1880 hypothetical protein YP_001724949.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli YP_001724950.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001724951.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_001724952.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001724953.1 PFAM: regulatory protein TetR; KEGG: sbo:SBO_1487 hypothetical protein YP_001724954.1 PFAM: protein of unknown function DUF1289; KEGG: sdy:SDY_1873 hypothetical protein YP_001724955.1 PFAM: aldo/keto reductase; KEGG: ssn:SSON_1509 hypothetical protein YP_001724956.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_001724957.1 PFAM: Fusaric acid resistance protein conserved region; KEGG: ssn:SSON_1511 hypothetical protein YP_001724958.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_1663 hypothetical protein YP_001724959.1 PFAM: protein of unknown function DUF1656; KEGG: ssn:SSON_1513 hypothetical protein YP_001724960.1 Transcription regulator that can both activate or repress expression YP_001724961.1 PFAM: 17 kDa surface antigen; KEGG: sdy:SDY_1864 putative outer membrane protein YP_001724962.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001724963.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_001724964.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001724965.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001724966.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001724967.1 PFAM: Glutathione S-transferase domain; KEGG: sdy:SDY_1858 glutathionine S-transferase YP_001724968.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001724969.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_001724970.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001724971.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001724972.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001724973.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001724974.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001724975.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: sdy:SDY_1850 hypothetical protein YP_001724976.1 KEGG: ssn:SSON_1532 hypothetical protein YP_001724977.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_001724978.1 KEGG: cko:CKO_01632 hypothetical protein YP_001724979.1 PFAM: Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain protein; Oxidoreductase domain; KEGG: sbo:SBO_1510 hypothetical protein YP_001724980.1 catalyzes the formation of inosine from adenosine YP_001724981.1 PFAM: aminotransferase class I and II; KEGG: sbo:SBO_1512 MalY YP_001724982.1 regulates malXY which are involved in maltose-glucose transport YP_001724983.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_001724984.1 PFAM: regulatory protein TetR; KEGG: sdy:SDY_1837 repressor for uid operon YP_001724985.1 PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: ssn:SSON_1543 beta-D-glucuronidase YP_001724986.1 KEGG: ssn:SSON_1545 membrane-associated protein YP_001724987.1 PFAM: protein of unknown function DUF945; KEGG: ssn:SSON_1546 hypothetical protein YP_001724988.1 KEGG: sbo:SBO_1523 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I YP_001724989.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sbo:SBO_1524 fumarase A YP_001724990.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001724991.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001724992.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_1825 sensor histidine protein kinase YP_001724993.1 response regulator in two-component regulatory system with RstB YP_001724994.1 PFAM: GlpM family protein; KEGG: sdy:SDY_1546 hypothetical protein YP_001724995.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_1547 putative oxidoreductase YP_001724996.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: sfv:SFV_1620 putative arginine/ornithine antiporter YP_001724997.1 PFAM: protein of unknown function DUF1471; KEGG: sdy:SDY_1549 hypothetical protein YP_001724998.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001724999.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001725000.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_001725001.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_001725002.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001725003.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: sfv:SFV_1613 hypothetical protein YP_001725004.1 required for growth and survival under moderately acid conditions YP_001725005.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1568 putative transport protein YP_001725006.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1569 putative transcriptional regulator LysR-type YP_001725007.1 PFAM: ROK family protein; KEGG: ssn:SSON_1570 putative NAGC-like transcriptional regulator YP_001725008.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001725009.1 PFAM: Chloride channel core; KEGG: sbo:SBO_1544 putative chloride channel YP_001725010.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_001725011.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_1546 putative DMSO reductase anchor subunit YP_001725012.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1567 putative oxidoreductase, Fe-S subunit YP_001725013.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sbo:SBO_1548 putative oxidoreductase, major subunit YP_001725014.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: stm:STM1499 putative dimethyl sulphoxide reductase, chain A1 YP_001725015.1 PFAM: protein of unknown function DUF1161; KEGG: sfv:SFV_1558 hypothetical protein YP_001725016.1 PFAM: protein of unknown function UPF0257; KEGG: sfv:SFV_1559 hypothetical protein YP_001725017.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cko:CKO_01578 hypothetical protein YP_001725018.1 PFAM: protein of unknown function DUF1283; KEGG: sfv:SFV_1561 hypothetical protein YP_001725019.1 PFAM: protein of unknown function UPF0060; KEGG: sdy:SDY_1577 hypothetical protein YP_001725020.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sfx:S1718 starvation sensing protein YP_001725021.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cko:CKO_01574 hypothetical protein YP_001725022.1 KEGG: cko:CKO_01573 hypothetical protein YP_001725023.1 PFAM: integrase family protein; KEGG: stm:STM0893 putative integrase YP_001725024.1 PFAM: protein of unknown function DUF1233 excisionase putative; KEGG: esa:ESA_01609 hypothetical protein YP_001725025.1 PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: sbo:SBO_0976 putative exodeoxyribonuclease VIII YP_001725026.1 PFAM: protein of unknown function DUF1482; KEGG: cko:CKO_01911 hypothetical protein YP_001725028.1 PFAM: protein of unknown function DUF1391; KEGG: ssn:SSON_0728 hypothetical prophage protein YP_001725029.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown. YP_001725030.1 KEGG: sfv:SFV_0741 putative regulator of cell division encoded by prophage YP_001725031.1 PFAM: protein of unknown function DUF1019 YP_001725032.1 KEGG: ent:Ent638_2616 hypothetical protein YP_001725033.1 PFAM: protein of unknown function DUF977; KEGG: sbo:SBO_0970 putative bacteriophage protein YP_001725034.1 KEGG: ent:Ent638_1018 putative methyltransferase YP_001725035.1 KEGG: sbo:SBO_0964 hypothetical protein YP_001725036.1 PFAM: Integrase catalytic region; KEGG: kpn:KPN_pKPN3p05906 Sea24 YP_001725037.1 KEGG: ent:Ent638_2935 hypothetical protein YP_001725038.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_001725039.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sfx:S1669 RelE protein YP_001725040.1 PFAM: Hok/gef cell toxic protein; KEGG: sdy:SDY_1432 polypeptide destructive to membrane potential YP_001725041.1 KEGG: sdy:SDY_1433 hypothetical protein YP_001725042.1 KEGG: sfl:SF2042 hypothetical protein YP_001725043.1 PFAM: protein of unknown function DUF1277; SMART: HNH nuclease; KEGG: sfl:SF1546 hypothetical bacteriophage protein YP_001725044.1 PFAM: antitermination protein; KEGG: esa:ESA_01015 hypothetical protein YP_001725045.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: spt:SPA1603 putative cold shock protein YP_001725046.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ent:Ent638_0166 putative cold-shock DNA-binding domain protein YP_001725048.1 PFAM: Lysis S family protein; KEGG: ssn:SSON_2438 hypothetical protein YP_001725049.1 PFAM: protein of unknown function DUF1327; KEGG: ssn:SSON_1892 hypothetical bacteriophage protein YP_001725050.1 PFAM: glycoside hydrolase family 24; KEGG: sfx:S0733 putative endolysin R of prophage CP-933V YP_001725051.1 KEGG: stm:STM1869 phage-tail assembly-like protein YP_001725052.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: stm:STM1996 putative cold-shock protein YP_001725054.1 PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA YP_001725055.1 PFAM: protein of unknown function DUF1398; KEGG: ssn:SSON_2432 hypothetical protein YP_001725057.1 PFAM: DNA packaging Nu1; KEGG: ssn:SSON_2431 bacteriophage DNA packaging protein YP_001725058.1 PFAM: terminase GpA; KEGG: ssn:SSON_2430 putative DNA packaging protein of prophage YP_001725059.1 PFAM: Head-to-tail joining protein W gpW family protein; KEGG: ssn:SSON_2429 putative head-tail joining protein of prophage YP_001725060.1 TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda; KEGG: ssn:SSON_2428 putative capsid structural protein of prophage YP_001725061.1 PFAM: peptidase S49; KEGG: ssn:SSON_2427 putative minor capsid protein precursor YP_001725062.1 PFAM: lambda head decoration protein D HDPD; KEGG: ssn:SSON_2426 putative head decoration protein YP_001725063.1 PFAM: major capsid protein E; KEGG: ssn:SSON_2425 putative major capsid protein YP_001725064.1 KEGG: ssn:SSON_2424 putative DNA-packaging protein YP_001725065.1 PFAM: head-tail attachment protein; KEGG: ssn:SSON_2423 putative head-tail joining protein of prophage YP_001725066.1 PFAM: Prophage minor tail Z family protein; KEGG: ssn:SSON_2422 putative tail component of prophage YP_001725067.1 PFAM: minor tail U; KEGG: ssn:SSON_2421 putative tail component of prophage YP_001725068.1 PFAM: Ig domain protein group 2 domain protein; KEGG: ssn:SSON_2420 putative tail component of prophage YP_001725069.1 TIGRFAM: phage minor tail protein G; PFAM: minor tail protein G; KEGG: ssn:SSON_2419 putative tail component of prophage YP_001725070.1 TIGRFAM: phage tail assembly protein T; PFAM: Minor tail T family protein; KEGG: ssn:SSON_2418 putative tail component of prophage YP_001725071.1 TIGRFAM: phage tail tape measure protein, lambda family; PFAM: Prophage tail length tape measure; KEGG: ssn:SSON_2417 putative tail length tape measure protein YP_001725072.1 PFAM: minor tail family protein; KEGG: ssn:SSON_2416 putative minor tail protein YP_001725073.1 TIGRFAM: phage minor tail protein L; PFAM: minor tail protein L; KEGG: ssn:SSON_2415 putative minor tail protein YP_001725074.1 PFAM: NLP/P60 protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ssn:SSON_2414 tail assembly protein YP_001725075.1 PFAM: lambda tail assembly I; KEGG: ssn:SSON_2413 putative tail component of prophage YP_001725076.1 PFAM: Fibronectin type III domain protein; Protein of unknown function DUF1983; KEGG: ssn:SSON_1763 host specificity protein YP_001725077.1 PFAM: virulence-related outer membrane protein; KEGG: sbo:SBO_1197 putative membrane protein precursor YP_001725078.1 PFAM: tail fiber repeat containing protein; tail fiber repeat 2 protein; Tail Collar domain protein; Prophage tail fibre domain protein; KEGG: ssn:SSON_2410 phage protein-related YP_001725079.1 PFAM: tail assembly chaperone gp38; KEGG: stm:STM1050 tail fiber assembly like-protein YP_001725080.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: sbl:Sbal_4419 resolvase, N-terminal domain YP_001725081.1 KEGG: ent:Ent638_2496 DNA-binding transcriptional regulator YP_001725082.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_1582 putative transport protein YP_001725083.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfx:S1678 putative oxidoreductase YP_001725084.1 KEGG: sdy:SDY_1584 hypothetical protein YP_001725085.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ssn:SSON_1588 hypothetical protein YP_001725086.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001725087.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: ssn:SSON_1590 dipeptidyl carboxypeptidase II YP_001725088.1 PFAM: CinA domain protein; KEGG: sdy:SDY_1588 hypothetical protein YP_001725089.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_1592 hypothetical protein YP_001725090.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1593 hypothetical protein YP_001725091.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_001725092.1 PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: sfv:SFV_1593 hypothetical protein YP_001725093.1 KEGG: sbo:SBO_1650 multiple antibiotic resistance protein YP_001725094.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF YP_001725095.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_001725096.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001725097.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1646 putative resistance/regulatory protein YP_001725098.1 KEGG: sfx:S1694 hypothetical protein YP_001725099.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sdy:SDY_1633 putative transcriptional regulator LysR-type YP_001725100.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_001725101.1 catalyzes the formation of glutamate from glutamine YP_001725102.1 KEGG: sbo:SBO_1641 hypothetical protein YP_001725103.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbo:SBO_1640 hypothetical protein YP_001725104.1 catalyzes the formation of D-tagaturonate from D-altronate YP_001725105.1 PFAM: protein of unknown function UPF0187; KEGG: sfv:SFV_1577 hypothetical protein YP_001725106.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001725107.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sdy:SDY_1624 hypothetical protein YP_001725108.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: stm:STM4078 putative fructose-1,6-bisphosphate aldolase YP_001725109.1 KEGG: stm:STM4077 putative ABC superfamily (peri_perm), sugar transport protein YP_001725110.1 PFAM: inner-membrane translocator; KEGG: sfv:SFV_1570 putative transport system permease protein YP_001725111.1 PFAM: inner-membrane translocator; KEGG: sfv:SFV_1569 putative transport system permease protein YP_001725112.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_1568 putative ATP-binding component of a transport system YP_001725113.1 PFAM: putative sugar-binding domain protein; KEGG: sfv:SFV_1567 putative transcriptional regulator YP_001725114.1 PFAM: carbohydrate kinase FGGY; KEGG: stt:t3546 putative sugar kinase YP_001725115.1 TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ssn:SSON_1611 hypothetical protein YP_001725116.1 PFAM: helix-turn-helix domain protein; KEGG: ssn:SSON_1613 persistence to inhibition of murein or DNA biosynthesis YP_001725117.1 TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: kpn:KPN_01668 persistence to inhibition of murein or DNA biosynthesis, DNA-binding regulator YP_001725118.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: cko:CKO_03711 hypothetical protein YP_001725119.1 PFAM: Fimbrial protein; KEGG: cko:CKO_03712 hypothetical protein YP_001725120.1 PFAM: Fimbrial protein; KEGG: sbo:SBO_4369 fimbrial morphology YP_001725121.1 PFAM: Fimbrial protein ; FimH mannose-binding domain protein; KEGG: ssn:SSON_1621 putative adhesin YP_001725122.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family YP_001725123.1 KEGG: sfx:S1655 hypothetical protein YP_001725124.1 regulates the cellular response to acid resistance YP_001725125.1 PFAM: sulfatase; KEGG: sbo:SBO_1558 putative sulfatase YP_001725126.1 PFAM: Radical SAM domain protein; KEGG: sfv:SFV_1723 putative enzyme YP_001725127.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_1627 putative ATP-binding component of a transport system YP_001725128.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1629 hypothetical protein YP_001725129.1 PFAM: peptidase M16 domain protein; KEGG: sbo:SBO_1562 putative peptidase YP_001725130.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_1563 glutamate decarboxylase isozyme YP_001725131.1 TIGRFAM: glutamate/g-aminobutyrate antiporter; PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1564 acid sensitivity protein, putative transporter YP_001725132.1 PFAM: protein of unknown function DUF187; KEGG: ssn:SSON_1633 hypothetical protein YP_001725133.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1634 hypothetical protein YP_001725134.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate YP_001725135.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001725136.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1637 putative hemin-binding lipoprotein YP_001725137.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1571 putative transport system permease protein YP_001725138.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1639 putative transport protein YP_001725139.1 KEGG: sbo:SBO_1573 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001725140.1 KEGG: sbo:SBO_1574 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001725141.1 PFAM: OsmC family protein; KEGG: sfv:SFV_1739 osmotically inducible protein YP_001725142.1 KEGG: sbo:SBO_1576 hypothetical protein YP_001725143.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_001725144.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001725145.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001725146.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sbo:SBO_1580 hypothetical protein YP_001725147.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_001725148.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbo:SBO_1582 formate dehydrogenase N, nitrate-inducible, iron-sulfur beta subunit YP_001725149.1 KEGG: ssn:SSON_1650 formate dehydrogenase-N, nitrate-inducible, alpha subunit; Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001725150.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_1651 hypothetical protein YP_001725151.1 KEGG: sbo:SBO_1585 putative outer membrane porin protein YP_001725152.1 KEGG: sfv:SFV_1753 putative glycoportein YP_001725153.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_1756 nitrite extrusion protein 2 YP_001725154.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1757 cryptic nitrate reductase 2, alpha subunit YP_001725155.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: ssn:SSON_1658 cryptic nitrate reductase 2, beta subunit YP_001725156.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: ssn:SSON_1659 cryptic nitrate reductase 2, delta subunit, assembly function YP_001725157.1 KEGG: sdy:SDY_1653 cryptic nitrate reductase 2, gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit YP_001725158.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sdy:SDY_1654 hypothetical protein YP_001725159.1 PFAM: N-acetyltransferase; KEGG: ssn:SSON_1662 putative N-hydroxyarylamine O-acetyltransferase YP_001725160.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: ssn:SSON_1663 hypothetical protein YP_001725161.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_001725162.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor YP_001725163.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: lpc:LPC_1850 reverse transcriptase YP_001725165.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001725166.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001725167.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ssn:SSON_1677 unknown protein associated with rhs element YP_001725168.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor YP_001725169.1 KEGG: ssn:SSON_1678 hypothetical protein YP_001725170.1 KEGG: sbo:SBO_1593 putative transferase YP_001725171.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1594 L-asparagine permease YP_001725172.1 KEGG: sbo:SBO_1595 putative receptor YP_001725173.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1682 putative outer membrane receptor for iron transport YP_001725174.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfv:SFV_1761 hypothetical protein YP_001725175.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1762 putative oxidoreductase YP_001725176.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_1688 putative resistance protein YP_001725177.1 PFAM: protein of unknown function DUF606; KEGG: sbo:SBO_1601 hypothetical protein YP_001725178.1 KEGG: sbo:SBO_1602 hypothetical protein YP_001725179.1 KEGG: sdy:SDY_1729 hypothetical protein YP_001725180.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001725181.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_1771 putative transport system permease protein YP_001725182.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ent:Ent638_2126 binding-protein-dependent transport systems inner membrane component YP_001725183.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_1696 putative ATP-binding component of a transport system YP_001725184.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1697 putative transport protein YP_001725185.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: ssn:SSON_1698 multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system YP_001725186.1 PFAM: helix-turn-helix domain protein; protein of unknown function UPF0150; KEGG: sdy:SDY_1736 hypothetical protein YP_001725187.1 PFAM: YcfA family protein; KEGG: cko:CKO_01475 hypothetical protein YP_001725188.1 KEGG: ssn:SSON_1702 hypothetical protein YP_001725189.1 PFAM: peptidase U32; KEGG: ssn:SSON_1703 putative collagenase YP_001725190.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: ssn:SSON_1704 hypothetical protein YP_001725191.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: cko:CKO_01471 hypothetical protein YP_001725192.1 KEGG: ssn:SSON_1709 putative virulence protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB YP_001725193.1 KEGG: sfv:SFV_1775 hypothetical protein YP_001725194.1 with TehA confers resistance to tellurite YP_001725195.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: sfv:SFV_1777 tellurite resistance YP_001725196.1 KEGG: sfv:SFV_1778 hypothetical protein YP_001725197.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_1660 acetyl transferase YP_001725198.1 PFAM: protein of unknown function DUF465; KEGG: sfv:SFV_1780 hypothetical protein YP_001725199.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001725200.1 PFAM: protein of unknown function DUF1338; KEGG: sdy:SDY_1757 hypothetical protein YP_001725201.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1720 putative transcriptional regulator LysR-type YP_001725202.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ssn:SSON_1721 methyl-accepting chemotaxis protein III YP_001725203.1 PFAM: Hok/gef cell toxic protein; KEGG: ent:Ent638_4258 Hok/gef cell toxic protein YP_001725204.1 KEGG: ssn:SSON_1723 hypothetical protein YP_001725205.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_001725206.1 KEGG: ssn:SSON_1725 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001725207.1 NAD-linked YP_001725208.1 PFAM: protein of unknown function DUF218; KEGG: sbo:SBO_1673 hypothetical protein YP_001725209.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001725210.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001725211.1 PFAM: phosphoesterase PA-phosphatase related; Dual specificity protein phosphatase; SMART: Protein-tyrosine phosphatase, catalytic; KEGG: sbo:SBO_1676 putative enzyme YP_001725212.1 KEGG: sdy:SDY_1779 hypothetical protein YP_001725213.1 PFAM: phosphatidate cytidylyltransferase; KEGG: sfx:S1465 putative phosphatidate cytidiltransferase YP_001725214.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfv:SFV_1801 probable enzyme YP_001725215.1 KEGG: sfv:SFV_1802 hypothetical protein YP_001725216.1 PFAM: aldo/keto reductase; KEGG: cko:CKO_01438 hypothetical protein YP_001725217.1 PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30 YP_001725218.1 TIGRFAM: phenylacetic acid degradation protein PaaY; KEGG: kpn:KPN_01481 phenylacetic acid degradation protein; putative transferase YP_001725219.1 TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: kpn:KPN_01480 transcriptional repressor for phenylacetic acid degradation YP_001725220.1 TIGRFAM: phenylacetate-CoA ligase; KEGG: kpn:KPN_01479 phenylacetate-CoA ligase YP_001725221.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001725222.1 TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: kpn:KPN_01477 phenylacetic acid degradation protein YP_001725223.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_001725224.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001725225.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: kpn:KPN_01474 probable enoyl-CoA hydratase YP_001725226.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: kpn:KPN_01473 probable phenylacetic acid degradation NADH oxidoreductase YP_001725227.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: kpn:KPN_01472 phenylacetic acid degradation protein YP_001725228.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01471 phenylacetic acid degradation protein YP_001725229.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001725230.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001725231.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001725232.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine YP_001725233.1 PFAM: Aldehyde Dehydrogenase_; KEGG: kpn:KPN_01455 phenylacetaldehyde dehydrogenase YP_001725234.1 activator of genes involved in phenylacetic acid catabolism YP_001725235.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_1683 hypothetical protein YP_001725236.1 KEGG: ssn:SSON_1742 hypothetical protein YP_001725237.1 KEGG: sbo:SBO_1685 hypothetical protein YP_001725238.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1744 fermentative D-lactate dehydrogenase, NAD-dependent YP_001725239.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sbo:SBO_1687 heat shock protein HslJ YP_001725240.1 KEGG: sdy:SDY_1462 hypothetical protein YP_001725241.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sbo:SBO_1688 putative oxidoreductase, Fe-S subunit YP_001725242.1 PFAM: porin Gram-negative type; KEGG: sbo:SBO_1689 putative outer membrane protein YP_001725243.1 PFAM: UspA domain protein; KEGG: sdy:SDY_1458 putative filament protein YP_001725244.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001725245.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001725246.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: sdy:SDY_1424 hypothetical protein YP_001725247.1 KEGG: sbo:SBO_1720 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001725248.1 PFAM: Smr protein/MutS2; KEGG: ssn:SSON_1791 hypothetical protein YP_001725249.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1792 putative transcriptional regulator LysR-type YP_001725250.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1793 putative aminohydrolase YP_001725251.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1794 hypothetical protein YP_001725252.1 TIGRFAM: AbgT transporter family; PFAM: AbgT putative transporter; KEGG: sbo:SBO_1725 putative pump protein (transport) YP_001725253.1 KEGG: sfv:SFV_1824 O-6-alkylguanine-DNA/cysteine-protein methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding YP_001725254.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001725255.1 with UspC and UspD is involved in resistance to UV irradiation YP_001725256.1 KEGG: ssn:SSON_1801 hypothetical protein YP_001725257.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_1732 hypothetical protein YP_001725258.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1804 putative transport periplasmic protein YP_001725259.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1734 putative transcriptional regulator LysR-type YP_001725260.1 PFAM: peptidase S15; KEGG: sfl:SF1337 hypothetical protein YP_001725261.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: sbo:SBO_1744 putative carboxypeptidase YP_001725262.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sfv:SFV_1341 putative muconate cycloisomerase I YP_001725263.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001725264.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001725265.1 PFAM: conserved hypothetical protein; KEGG: sfv:SFV_1338 hypothetical protein YP_001725266.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: sbo:SBO_1749 YcjX YP_001725267.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sfx:S1409 putative LacI-type transcriptional regulator YP_001725268.1 KEGG: ent:Ent638_2156 outer membrane protein G precursor YP_001725269.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sfv:SFV_1334 putative ATP-binding component of a transport system YP_001725270.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ssn:SSON_1823 putative beta-phosphoglucomutase YP_001725271.1 PFAM: glycoside hydrolase family 65 domain protein; glycoside hydrolase family 65 central catalytic; KEGG: ssn:SSON_1824 hypothetical protein YP_001725272.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ssn:SSON_1825 putative dehydrogenase YP_001725273.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ssn:SSON_1826 putative transient receptor potential locus YP_001725274.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1329 putative oxidoreductase YP_001725275.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_1328 putative transport system permease protein YP_001725276.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1829 putative binding-protein dependent transport protein YP_001725277.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1830 putative transport periplasmic protein YP_001725278.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ent:Ent638_2165 alpha amylase, catalytic region YP_001725279.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_001725280.1 TIGRFAM: phage shock protein PspD; PFAM: shock protein PspD; KEGG: sdy:SDY_1937 phage shock protein YP_001725281.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001725282.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001725283.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001725284.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001725285.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate YP_001725286.1 PFAM: FAD dependent oxidoreductase; KEGG: ssn:SSON_1839 probable oxidoreductase YP_001725287.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_001725288.1 regulates genes involved in putrescine degradation YP_001725289.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_001725290.1 PFAM: glutamine synthetase catalytic region; KEGG: sfx:S1384 putative glutamine synthetase YP_001725291.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1766 putative amino acid/amine transport protein YP_001725292.1 KEGG: ssn:SSON_1845 hypothetical protein YP_001725293.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1768 SapA YP_001725294.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1769 SapB YP_001725295.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1770 SapC YP_001725296.1 KEGG: ssn:SSON_1849 putative ATP-binding protein of peptide transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001725297.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_1772 putative ATP-binding protein of peptide transport system YP_001725298.1 PFAM: protein of unknown function DUF559; KEGG: sbo:SBO_1773 hypothetical protein YP_001725299.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001725300.1 KEGG: sbo:SBO_1775 putative oxidoreductase YP_001725301.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001725302.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_001725303.1 KEGG: sdy:SDY_1362 hypothetical protein YP_001725304.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sdy:SDY_1361 putative DeoR-type transcriptional regulator YP_001725305.1 KEGG: sbo:SBO_1781 osmotically inducible lipoprotein YP_001725306.1 involved in start site selection during the initiation of translation YP_001725307.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001725308.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ssn:SSON_1860 putative heat shock protein YP_001725309.1 PFAM: protein of unknown function DUF1049; KEGG: sbo:SBO_1785 hypothetical protein YP_001725310.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: sdy:SDY_1354 non-essential phosphatidylglycerophosphate phosphatase, membrane bound YP_001725311.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001725312.1 Catalyzes the conversion of citrate to isocitrate YP_001725313.1 KEGG: ssn:SSON_1865 hypothetical protein YP_001725314.1 KEGG: sdy:SDY_1348 hypothetical protein YP_001725315.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001725316.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001725317.1 KEGG: sdy:SDY_1343 hypothetical protein YP_001725318.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001725319.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sdy:SDY_1341 putative oxidoreductase YP_001725320.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001725321.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001725322.1 KEGG: sbo:SBO_1798 hypothetical protein YP_001725323.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: sbo:SBO_1799 hypothetical protein YP_001725324.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfx:S1354 putative enzyme YP_001725325.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001725326.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_001725327.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001725328.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001725329.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001725330.1 KEGG: sfv:SFV_1273 hypothetical protein YP_001725331.1 PFAM: protein of unknown function DUF892; KEGG: sfv:SFV_1272 putative structural proteins YP_001725332.1 PFAM: protein of unknown function DUF892; KEGG: sfv:SFV_1271 hypothetical protein YP_001725333.1 receptor for colicin S4 YP_001725334.1 PFAM: protein of unknown function UPF0259; KEGG: ssn:SSON_1911 hypothetical protein YP_001725335.1 Involved in cell division; probably involved in intracellular septation YP_001725336.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_001725337.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001725338.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001725339.1 PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: sbo:SBO_1817 putative potassium channel protein YP_001725340.1 KEGG: cko:CKO_01327 hypothetical protein YP_001725341.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001725342.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001725343.1 KEGG: sfv:SFV_1259 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001725344.1 KEGG: sfv:SFV_1258 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001725345.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1935 oligopeptide transport permease protein-like protein YP_001725346.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1823 oligopeptide transport permease protein YP_001725347.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1824 oligopeptide transport periplasmic binding protein YP_001725348.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ssn:SSON_1938 putative channel protein YP_001725349.1 PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: sdy:SDY_1295 CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase/pyruvate-formate-lyase deactivase YP_001725350.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001725351.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sdy:SDY_1289 DNA-binding protein HLP-II YP_001725352.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001725353.1 PFAM: response regulator receiver; KEGG: sdy:SDY_1287 Hnr protein YP_001725354.1 PFAM: Patatin; KEGG: ssn:SSON_1945 hypothetical protein YP_001725355.1 PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1836 hypothetical protein YP_001725356.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001725357.1 KEGG: ssn:SSON_1949 nitrate reductase 1, cytochrome b(NR), gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit YP_001725358.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: ssn:SSON_1950 nitrate reductase 1, delta subunit, assembly function YP_001725359.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: sbo:SBO_1841 nitrate reductase 1 beta subunit YP_001725360.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1240 nitrate reductase 1, alpha subunit YP_001725361.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1843 nitrite extrusion protein YP_001725362.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sfv:SFV_1238 nitrate/nitrate sensor, histidine protein kinase YP_001725363.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_001725364.1 KEGG: ssn:SSON_1957 putative factor YP_001725365.1 PFAM: DsrE family protein; KEGG: sdy:SDY_1271 hypothetical protein YP_001725366.1 PFAM: ChaC family protein; KEGG: sbo:SBO_1848 cation transport regulator YP_001725367.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_001725368.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ssn:SSON_1961 sodium-calcium/proton antiporter YP_001725369.1 KEGG: sfv:SFV_1231 hypothetical protein YP_001725370.1 KEGG: sbo:SBO_1851 hypothetical protein YP_001725371.1 KEGG: sbo:SBO_1851 hypothetical protein YP_001725372.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001725373.1 KEGG: sfv:SFV_1228 hypothetical protein YP_001725374.1 PFAM: Invasion gene expression up-regulator SirB; KEGG: sdy:SDY_1262 hypothetical protein YP_001725375.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_001725376.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001725377.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001725378.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001725379.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001725380.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001725381.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001725382.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001725383.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001725384.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001725385.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfx:S1289 putative adhesion and penetration protein YP_001725386.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_001725387.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001725388.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_001725389.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL YP_001725390.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_001725391.1 PFAM: Transglycosylase-associated protein; KEGG: sdy:SDY_1234 hypothetical protein YP_001725392.1 PFAM: type IV pilus assembly PilZ; YcgR family protein; KEGG: sbo:SBO_1878 hypothetical protein YP_001725393.1 PFAM: Lytic transglycosylase catalytic; KEGG: ssn:SSON_1184 murein transglycosylase E YP_001725394.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_001725395.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001725396.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_001725397.1 catalyzes the oxidative deamination of D-amino acids YP_001725398.1 PFAM: SpoVR family protein; KEGG: ssn:SSON_1180 putative sporulation protein YP_001725399.1 Multifunctional regulator of fatty acid metabolism YP_001725400.1 involved in regulation of intracellular pH under alkaline conditions YP_001725401.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001725402.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001725403.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001725404.1 PFAM: protein of unknown function UPF0153; KEGG: sfv:SFV_1188 hypothetical protein YP_001725405.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sbo:SBO_1166 putative isomerase YP_001725406.1 PFAM: protein of unknown function DUF709; KEGG: sbo:SBO_1165 hypothetical protein YP_001725407.1 PFAM: peptidase domain protein; KEGG: sdy:SDY_1210 hypothetical protein YP_001725408.1 PFAM: Fels-1 Propage domain protein; KEGG: ssn:SSON_1166 hypothetical protein YP_001725409.1 blocks the formation of polar Z-ring septums YP_001725410.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001725411.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001725412.1 KEGG: sbo:SBO_1897 hypothetical protein YP_001725413.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001725414.1 KEGG: ssn:SSON_1161 hypothetical protein YP_001725416.1 PFAM: EAL domain protein; KEGG: sfx:S1241 hypothetical protein YP_001725418.1 KEGG: ent:Ent638_1754 hypothetical protein YP_001725420.1 KEGG: ent:Ent638_1756 hypothetical protein YP_001725421.1 PFAM: EAL domain protein; BLUF domain protein; KEGG: kpn:KPN_00782 hypothetical protein YP_001725422.1 PFAM: regulatory protein MerR; KEGG: ssn:SSON_1157 putative transcriptional regulator YP_001725423.1 PFAM: protein of unknown function DUF1398; KEGG: ssn:SSON_1156 hypothetical protein YP_001725424.1 KEGG: sdy:SDY_2015 hypothetical protein YP_001725425.1 Converts isocitrate to alpha ketoglutarate YP_001725426.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA YP_001725427.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_2018 putative phosphohydrolase YP_001725428.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001725429.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001725430.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001725431.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001725432.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: sbo:SBO_1910 sensor protein PhoQ YP_001725433.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: sbo:SBO_1911 hypothetical protein YP_001725434.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001725435.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_001725436.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_001725437.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_001725438.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_001725439.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001725440.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_001725441.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001725442.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_001725443.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001725444.1 PFAM: acyltransferase 3; KEGG: ssn:SSON_1135 hypothetical protein YP_001725445.1 KEGG: sfv:SFV_1134 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001725446.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2037 hypothetical protein YP_001725447.1 PFAM: protein of unknown function DUF1471; KEGG: sdy:SDY_2038 hypothetical protein YP_001725448.1 PFAM: regulatory protein TetR; KEGG: sdy:SDY_2039 hypothetical protein YP_001725449.1 PFAM: 17 kDa surface antigen; KEGG: sdy:SDY_2040 hypothetical protein YP_001725450.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sfx:S1193 respiratory NADH dehydrogenase YP_001725451.1 PFAM: protein of unknown function UPF0227; KEGG: sdy:SDY_2042 hypothetical protein YP_001725452.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001725453.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_001725454.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: sdy:SDY_2045 hypothetical protein YP_001725455.1 PFAM: protein of unknown function DUF1425; KEGG: sdy:SDY_2046 hypothetical protein YP_001725456.1 PFAM: histidine triad (HIT) protein; KEGG: sdy:SDY_2047 hypothetical protein YP_001725457.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sdy:SDY_2048 outer membrane receptor for ferric iron uptake YP_001725458.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001725459.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: sdy:SDY_2050 hypothetical protein YP_001725460.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001725461.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001725462.1 PFAM: aminodeoxychorismate lyase; KEGG: sbo:SBO_1966 putative thymidylate kinase YP_001725463.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001725464.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001725465.1 carries the fatty acid chain in fatty acid biosynthesis YP_001725466.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001725467.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: sfv:SFV_1112 malonyl-CoA-[acyl-carrier-protein] transacylase YP_001725468.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001725469.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001725470.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001725471.1 PFAM: protein of unknown function DUF177; KEGG: sbo:SBO_1975 hypothetical protein YP_001725472.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001725473.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001725474.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001725475.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_001725476.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001725477.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001725478.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001725479.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001725480.1 makes up the distal portion of the flagellar basal body rod YP_001725481.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001725482.1 the hook connects flagellar basal body to the flagellar filament YP_001725483.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001725484.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001725485.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001725486.1 required for the assembly of the flagellar basal body P-ring YP_001725487.1 regulates the flagellar specific sigma28 transcription factor YP_001725488.1 PFAM: FlgN family protein; KEGG: ssn:SSON_1090 protein of flagellar biosynthesis YP_001725489.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: sbo:SBO_1995 putative virulence factor YP_001725490.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sdy:SDY_2084 putative virulence factor YP_001725491.1 PFAM: protein of unknown function DUF480; KEGG: ssn:SSON_1087 hypothetical protein YP_001725492.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_1998 RimJ YP_001725493.1 Confers resistance to norfloxacin and enoxacin YP_001725494.1 cofactor involved in the reduction of disulfides YP_001725495.1 PFAM: protein of unknown function DUF1439; KEGG: sbo:SBO_2001 hypothetical protein YP_001725496.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001725497.1 PFAM: DinI family protein; KEGG: ssn:SSON_1081 damage-inducible protein I YP_001725498.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001725499.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001725500.1 KEGG: sdy:SDY_2097 hypothetical protein YP_001725501.1 PFAM: cytochrome B561; KEGG: ssn:SSON_1077 putative cytochrome YP_001725502.1 PFAM: YceI family protein; KEGG: sbo:SBO_2008 hypothetical protein YP_001725503.1 PFAM: Rhodanese domain protein; KEGG: sfv:SFV_1078 hypothetical protein YP_001725504.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001725505.1 Confers resistance to fosfomycin and deoxycholate YP_001725506.1 KEGG: sdy:SDY_2299 acidic protein YP_001725507.1 PFAM: protein of unknown function DUF1375; KEGG: sdy:SDY_2300 hypothetical protein YP_001725508.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001725509.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001725510.1 required for the transfer of succinyl residues to the glucan backbone YP_001725511.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: sfx:S1116 putative synthase YP_001725512.1 PFAM: Appr-1-p processing domain protein; KEGG: sbo:SBO_2021 putative polyprotein YP_001725513.1 KEGG: ssn:SSON_1057 hypothetical protein YP_001725514.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_001725515.1 KEGG: sbo:SBO_2026 CsgA YP_001725516.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_001725517.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_001725518.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001725519.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001725520.1 PFAM: Curli production assembly/transport component CsgG; KEGG: ssn:SSON_1046 curli production assembly/transport component, 2nd curli operon YP_001725521.1 PFAM: protein of unknown function DUF1097; KEGG: sbo:SBO_2032 hypothetical protein YP_001725522.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfv:SFV_1046 putative oxidoreductase component YP_001725523.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sbo:SBO_2034 hypothetical protein YP_001725524.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1042 putative dehydrogenase YP_001725525.1 KEGG: sfv:SFV_1042 hypothetical protein YP_001725526.1 KEGG: sfv:SFV_1041 hypothetical protein YP_001725527.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1 YP_001725528.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2 YP_001725529.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1377 hypothetical protein YP_001725530.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia YP_001725531.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_001725532.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_001725533.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export YP_001725534.1 PFAM: PhoH family protein; KEGG: sbo:SBO_2038 PhoB-dependent, ATP-binding pho regulon component YP_001725535.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbo:SBO_2039 hypothetical protein YP_001725536.1 KEGG: ssn:SSON_1037 hypothetical protein YP_001725537.1 TIGRFAM: FTR1 family protein; PFAM: iron permease FTR1; KEGG: ssn:SSON_1036 high-affinity iron permease YP_001725538.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: sbo:SBO_2042 major sodium/proline symporter YP_001725539.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001725540.1 PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YcdC domain protein; KEGG: sfv:SFV_1025 putative tet operon regulator YP_001725541.1 PFAM: luciferase family protein; KEGG: sfv:SFV_1024 hypothetical protein YP_001725542.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1030 putative synthetase YP_001725543.1 PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_0985 hypothetical protein YP_001725544.1 PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_1027 putative acetyltransferase YP_001725545.1 PFAM: nitroreductase; KEGG: sfv:SFV_1020 putative enzyme YP_001725546.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: sfv:SFV_1019 hypothetical protein YP_001725547.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_1024 putative transport protein YP_001725548.1 KEGG: cko:CKO_02046 hypothetical protein YP_001725549.1 stationary phase protein that binds TrpR repressor YP_001725550.1 KEGG: sdy:SDY_0979 hypothetical protein YP_001725551.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 periplasmic glucose-1-phosphatase YP_001725552.1 KEGG: sfv:SFV_1013 hypothetical protein YP_001725553.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_001725554.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_001725555.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001725556.1 KEGG: sfv:SFV_1007 trimethylamine N-oxide reductase subunit; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001725557.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: ssn:SSON_1004 trimethylamine N-oxide reductase, cytochrome c-type subunit YP_001725558.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001725559.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001725560.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_001725561.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_1002 hypothetical protein YP_001725562.1 PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA YP_001725563.1 KEGG: ssn:SSON_0998 Sfa YP_001725564.1 KEGG: sec:SC1999 putative cold-shock protein YP_001725565.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sbo:SBO_2241 CspG YP_001725566.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sdy:SDY_0964 cold shock-like protein YP_001725567.1 KEGG: sdy:SDY_0963 hypothetical protein YP_001725568.1 KEGG: sbo:SBO_2244 putative regulator YP_001725569.1 PFAM: protein of unknown function DUF1017; KEGG: ssn:SSON_0992 hypothetical protein YP_001725570.1 PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: sbo:SBO_2246 hypothetical protein YP_001725571.1 PFAM: polysaccharide export protein; KEGG: ssn:SSON_0990 putative function in exopolysaccharide production YP_001725572.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk YP_001725573.1 KEGG: sbo:SBO_2249 hypothetical protein; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein YP_001725574.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_0987 phosphoanhydride phosphorylase YP_001725575.1 KEGG: ssn:SSON_0985 probable third cytochrome oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001725576.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sfv:SFV_0987 probable third cytochrome oxidase, subunit I YP_001725577.1 PFAM: HupH hydrogenase expression protein; KEGG: sfx:S1045 hydrogenase-1 operon protein hyaF YP_001725578.1 involved in processing hydrogenase proteins HyaA and HyaB YP_001725579.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_001725580.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: sdy:SDY_0949 probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit YP_001725581.1 PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30 YP_001725582.1 KEGG: sdy:SDY_0947 hydrogenase-1 small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein YP_001725583.1 PFAM: protein of unknown function UPF0005; KEGG: sdy:SDY_0945 putative carrier/transport protein YP_001725584.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_001725585.1 catalyzes the hydrolysis of acylphosphate YP_001725586.1 PFAM: conserved hypothetical protein; SMART: PUA domain containing protein; KEGG: sdy:SDY_0942 hypothetical protein YP_001725587.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: sbo:SBO_2265 hypothetical protein YP_001725588.1 PFAM: CoA-binding domain protein; KEGG: sbo:SBO_2266 hypothetical protein YP_001725589.1 KEGG: sdy:SDY_0939 hypothetical protein YP_001725590.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001725591.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001725592.1 PFAM: protein of unknown function DUF307; KEGG: sbo:SBO_2270 hypothetical protein YP_001725593.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_0964 hypothetical protein YP_001725594.1 PFAM: TfoX domain protein; KEGG: sdy:SDY_0934 hypothetical protein YP_001725595.1 PFAM: cell division inhibitor SulA; KEGG: ssn:SSON_0962 suppressor of lon; inhibits cell division and FtsZ ring formation YP_001725596.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001725597.1 PFAM: protein of unknown function DUF1047; KEGG: sdy:SDY_0929 putative dehydrogenase YP_001725598.1 PFAM: peptidase S16 lon domain protein; KEGG: ssn:SSON_0959 putative ATP-dependent protease YP_001725599.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001725600.1 PFAM: ribosome modulation factor; KEGG: sdy:SDY_0926 ribosome modulation factor YP_001725601.1 PFAM: protein of unknown function DUF330; KEGG: sfv:SFV_0961 hypothetical protein YP_001725602.1 PFAM: Mammalian cell entry related domain protein; KEGG: sdy:SDY_0924 paraquat-inducible protein B YP_001725603.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: sbo:SBO_2281 paraquat-inducible protein A YP_001725604.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001725605.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001725606.1 PFAM: ferredoxin; MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: ssn:SSON_0951 hypothetical protein YP_001725607.1 PFAM: protein of unknown function DUF1379; KEGG: ssn:SSON_0950 hypothetical protein YP_001725608.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001725609.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_0948 putative chaperone YP_001725610.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0947 putative fimbrial-like protein YP_001725611.1 PFAM: Fimbrial protein; KEGG: sfv:SFV_0951 putative fimbrial-like protein YP_001725612.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0945 FimH-like protein YP_001725613.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_0943 putative chaperone YP_001725614.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0942 putative fimbrial-like protein YP_001725615.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2228 hypothetical protein YP_001725616.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_001725617.1 catalyzes the release of sulfite from alkanesulfonates YP_001725618.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_001725619.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001725620.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: sbo:SBO_2223 aminopeptidase N YP_001725621.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001725622.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001725623.1 outer membrane porin F; 1a; Ia; b YP_001725624.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001725625.1 PFAM: beta-lactamase domain protein; KEGG: sbo:SBO_2218 hypothetical protein YP_001725626.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: sdy:SDY_2331 hypothetical protein YP_001725627.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sbo:SBO_2216 putative amidase YP_001725628.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001725629.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001725630.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001725631.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001725632.1 PFAM: protein of unknown function DUF218; KEGG: sfv:SFV_0921 hypothetical protein YP_001725633.1 KEGG: sbo:SBO_2207 hypothetical protein YP_001725634.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001725635.1 PFAM: protein of unknown function DUF343; KEGG: sdy:SDY_2341 hypothetical protein YP_001725636.1 PFAM: protein of unknown function DUF1006; KEGG: sdy:SDY_2342 hypothetical protein YP_001725637.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001725638.1 involved in the transport of lipid A across the inner membrane YP_001725639.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: sdy:SDY_2345 hypothetical protein YP_001725640.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001725641.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001725642.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001725643.1 PFAM: peptidase M48 Ste24p; KEGG: ssn:SSON_0911 putative heat shock protein YP_001725644.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001725645.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001725646.1 PFAM: protein of unknown function DUF421; KEGG: sbo:SBO_2192 hypothetical protein YP_001725647.1 PFAM: protein of unknown function DUF181; KEGG: sbo:SBO_2191 hypothetical protein YP_001725648.1 PFAM: formate/nitrite transporter; KEGG: sdy:SDY_2357 probable formate transporter YP_001725649.1 KEGG: ssn:SSON_0904 formate acetyltransferase 1; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001725650.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001725651.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2185 hypothetical protein YP_001725652.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2184 putative transcriptional regulator LysR-type YP_001725653.1 PFAM: amino acid permease-associated region; KEGG: stm:STM0969 putative amino-acid transporter YP_001725654.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_2363 putative transport YP_001725655.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_0898 hypothetical protein YP_001725656.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_0985 anaerobic dimethyl sulfoxide reductase subunit C YP_001725657.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_0896 anaerobic dimethyl sulfoxide reductase subunit B YP_001725658.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: ssn:SSON_0895 anaerobic dimethyl sulfoxide reductase subunit A YP_001725659.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001725660.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: sdy:SDY_2369 putative polynucleotide enzyme YP_001725661.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001725662.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_001725663.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001725664.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_001725665.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001725666.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001725667.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001725668.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001725669.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001725670.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001725671.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible YP_001725672.1 with MacA is involved in the export of macrolide YP_001725673.1 confers macrolide resistance via active drug efflux YP_001725674.1 PFAM: protein of unknown function DUF535; KEGG: ssn:SSON_0864 putative enzyme YP_001725675.1 KEGG: sfx:S0876 predicted ATP-dependent endonuclease of the OLD family YP_001725676.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001725677.1 PFAM: protein of unknown function DUF340 membrane; KEGG: sbo:SBO_0807 putative surface protein YP_001725678.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001725679.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ssn:SSON_0858 putative enzyme YP_001725680.1 catalyzes the formation of acetate from pyruvate YP_001725681.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_001725682.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sbo:SBO_0802 putative dTDP-glucose enzyme YP_001725683.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: ssn:SSON_0854 putative nucleotide di-P-sugar epimerase or dehydratase YP_001725684.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sdy:SDY_2396 putative regulator YP_001725685.1 PFAM: protein of unknown function DUF74; KEGG: sdy:SDY_2397 hypothetical protein YP_001725686.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_001725687.1 With ArtMQJI transports arginine across the inner membrane YP_001725688.1 KEGG: sbo:SBO_0797 arginine 3rd transport system periplasmic binding protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor YP_001725689.1 with ArtPMJI transports arginine across the inner membrane YP_001725690.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001725691.1 KEGG: sbo:SBO_0794 arginine 3rd transport system periplasmic binding protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor YP_001725692.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001725693.1 KEGG: sdy:SDY_0737 hypothetical protein YP_001725694.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_0738 putrescine transport protein YP_001725695.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfx:S0852 putrescine transport protein; permease YP_001725696.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001725697.1 PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_0788 periplasmic putrescine-binding protein YP_001725698.1 KEGG: sbo:SBO_0787 putative sensory transduction regulator YP_001725699.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_001725700.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001725701.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001725702.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001725703.1 KEGG: sdy:SDY_0747 hypothetical protein YP_001725704.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: ssn:SSON_0832 putative transport protein YP_001725705.1 PFAM: transcriptional activator Ogr/delta; KEGG: sbo:SBO_0780 putative bacteriophage late gene regulator YP_001725706.1 PFAM: late control D family protein; KEGG: stt:t3444 putative regulator of late gene expression YP_001725707.1 PFAM: P2 GpU family protein; KEGG: sbo:SBO_0778 putative bacteriophage tail protein YP_001725708.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: stt:t2662 putative bacteriophage tail protein YP_001725709.1 PFAM: tail E family protein; KEGG: sbo:SBO_0776 putative phage tail protein YP_001725710.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: sbo:SBO_0775 probable major tail tube protein YP_001725711.1 PFAM: tail sheath protein; KEGG: sbo:SBO_0774 probable major tail sheath protein YP_001725712.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: sbo:SBO_0773 inversion of adjacent DNA; at locus of E14 element YP_001725713.1 PFAM: Tail Collar domain protein; KEGG: stt:t1351 bacteriophage tail fiber protein YP_001725714.1 PFAM: tail assembly chaperone gp38; KEGG: stt:t1349 putative bacteriophage tail fiber assembly protein YP_001725715.1 PFAM: tail assembly chaperone gp38; KEGG: sbo:SBO_0772 hypothetical protein YP_001725716.1 KEGG: stt:t3433 probable variable tail fiber protein YP_001725717.1 TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: stt:t4306 putative phage tail protein YP_001725718.1 PFAM: Baseplate J family protein; KEGG: stt:t3431 phage baseplate assembly protein YP_001725719.1 PFAM: GPW/gp25 family protein; KEGG: stt:t3430 phage baseplate assembly protein YP_001725720.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: stt:t3429 putative phage baseplate assembly protein YP_001725721.1 KEGG: dps:DP2013 hypothetical protein YP_001725722.1 TIGRFAM: phage virion morphogenesis protein; PFAM: virion morphogenesis (putative tail completion) protein; KEGG: stt:t3428 putative phage tail protein YP_001725723.1 PFAM: P2 phage tail completion R family protein; KEGG: stt:t3427 putative phage tail protein YP_001725724.1 KEGG: stm:STM2714 lysis-like protein YP_001725725.1 PFAM: glycoside hydrolase family 24; KEGG: sbo:SBO_0765 putative lysozyme protein R of prophage CP-933K YP_001725726.1 KEGG: stt:t3423 possible secretory protein YP_001725727.1 PFAM: tail X family protein; KEGG: stt:t3422 probable phage tail protein YP_001725728.1 PFAM: head completion protein; KEGG: sbo:SBO_0762 putative capsid completion protein YP_001725729.1 PFAM: small terminase subunit; KEGG: stt:t3420 terminase, endonuclease subunit YP_001725730.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: stt:t3419 major capsid protein YP_001725731.1 PFAM: capsid scaffolding; KEGG: stt:t3418 putative capsid scaffolding protein YP_001725732.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: stt:t3417 terminase, ATPase subunit YP_001725733.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: stt:t3416 probable capsid portal protein YP_001725735.1 KEGG: cbe:Cbei_0882 hypothetical protein YP_001725736.1 KEGG: stm:STM2726 hypothetical protein YP_001725737.1 PFAM: DinI family protein; KEGG: sbo:SBO_0753 putative damage-inducible protein YP_001725738.1 KEGG: stt:t3411 hypothetical protein YP_001725739.1 PFAM: replication gene A; KEGG: stt:t3410 possible endonuclease YP_001725740.1 KEGG: eba:ebA7273 hypothetical protein YP_001725741.1 KEGG: stt:t3409 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001725742.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: stt:t3408 hypothetical protein YP_001725743.1 KEGG: stt:t3407 hypothetical protein YP_001725744.1 KEGG: stt:t3406 hypothetical protein YP_001725745.1 KEGG: ent:Ent638_1345 hypothetical protein YP_001725746.1 PFAM: regulatory CII family protein; KEGG: stt:t3404 regulatory protein CII YP_001725747.1 KEGG: sbo:SBO_0749 hypothetical protein YP_001725748.1 PFAM: CI repressor; KEGG: sbo:SBO_0748 repressor protein YP_001725749.1 KEGG: sdy:SDY_1763 hypothetical protein YP_001725750.1 PFAM: integrase family protein; KEGG: stt:t3400 probable bacteriophage integrase YP_001725751.1 PFAM: regulatory protein TetR; KEGG: sbo:SBO_0742 putative DeoR-type transcriptional regulator YP_001725752.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_0741 putative DeoR-type transcriptional regulator YP_001725753.1 KEGG: sfv:SFV_0829 hypothetical protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3 YP_001725754.1 KEGG: sbo:SBO_0739 hypothetical protein YP_001725755.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0838 chloramphenicol resistance pump Cmr YP_001725756.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_0826 hypothetical protein YP_001725757.1 PFAM: regulatory protein DeoR; KEGG: sfv:SFV_0825 transcriptional repressor for deo operon, tsx, NupG YP_001725758.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001725759.1 PFAM: Glutathione S-transferase domain; KEGG: sfx:S0831 putative transferase YP_001725760.1 PFAM: glucose sorbosone dehydrogenase; KEGG: sbo:SBO_0733 putative dehydrogenase YP_001725761.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001725762.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001725763.1 PFAM: protein of unknown function DUF1044; KEGG: plu:plu2130 hypothetical protein YP_001725764.1 PFAM: helix-turn-helix domain protein; KEGG: shn:Shewana3_4237 transcriptional regulator, XRE family YP_001725765.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbo:SBO_0726 hypothetical protein YP_001725766.1 PFAM: EAL domain protein; KEGG: sfv:SFV_0816 hypothetical protein YP_001725767.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_0722 putative transport system permease protein YP_001725768.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_0756 putative transport system permease protein YP_001725769.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_0720 putative transport protein YP_001725770.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_001725771.1 PFAM: peptidase T2 asparaginase 2; KEGG: sfx:S0821 putative asparaginase YP_001725772.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001725773.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001725774.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001725775.1 KEGG: sfv:SFV_0807 putative pyruvate formate-lyase 2 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein YP_001725776.1 KEGG: ssn:SSON_0805 putative formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001725777.1 KEGG: sfv:SFV_0805 hypothetical protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3 YP_001725778.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0710 putative ATP-binding component of a transport system YP_001725779.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_0777 hypothetical protein YP_001725780.1 PFAM: Citrate transporter; KEGG: ssn:SSON_0797 hypothetical protein YP_001725781.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_001725782.1 KEGG: sec:SC0831 hypothetical protein YP_001725783.1 PFAM: sulfatase; KEGG: sbo:SBO_0706 putative enzyme YP_001725784.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001725785.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_0793 putative transmembrane subunit YP_001725786.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001725787.1 similar to periplasmic-binding component of ABC transporters YP_001725788.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001725789.1 similar to ATP-binding component of ABC transporters YP_001725790.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0788 putative transport protein YP_001725791.1 PFAM: protein of unknown function DUF890; KEGG: sbo:SBO_0697 hypothetical protein YP_001725792.1 PFAM: protein of unknown function DUF1471; KEGG: ssn:SSON_0786 hypothetical protein YP_001725793.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_001725794.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: sbo:SBO_0692 putative enzyme YP_001725795.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: ssn:SSON_0782 hypothetical protein YP_001725796.1 PFAM: protein of unknown function DUF1471; KEGG: sfv:SFV_0785 hypothetical protein YP_001725797.1 PFAM: Malate/L-lactate dehydrogenase; KEGG: ssn:SSON_0780 putative dehydrogenase YP_001725798.1 PFAM: glycosyl transferase family 3; KEGG: sbo:SBO_0688 putative enzyme YP_001725799.1 helicase involved in DNA repair and perhaps also replication YP_001725800.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_0686 hypothetical protein YP_001725801.1 this helicase is not essential cell growth YP_001725802.1 PFAM: regulatory protein TetR; Transcriptional regulator TetR; KEGG: sdy:SDY_0807 putative transcriptional regulator YP_001725803.1 PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_0778 hypothetical protein YP_001725804.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfl:SF0744 putative ATP-binding component of a transport system YP_001725805.1 PFAM: ABC-2 type transporter; KEGG: ssn:SSON_0772 hypothetical protein YP_001725806.1 PFAM: ABC-2 type transporter; KEGG: ssn:SSON_0771 hypothetical protein YP_001725807.1 KEGG: sbo:SBO_0679 hypothetical protein YP_001725808.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ssn:SSON_0769 hypothetical protein YP_001725809.1 KEGG: ssn:SSON_0768 putative synthetase YP_001725810.1 KEGG: sfv:SFV_0771 hypothetical protein YP_001725811.1 PFAM: protein of unknown function UPF0005; KEGG: sfv:SFV_0770 hypothetical protein YP_001725812.1 PFAM: protein of unknown function UPF0005; KEGG: sbo:SBO_0673 hypothetical protein YP_001725813.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001725814.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001725815.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001725816.1 TIGRFAM: molybdenum cofactor synthesis domain protein; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: sbo:SBO_0669 molybdopterin biosynthesis, protein B YP_001725817.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001725818.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: sbo:SBO_0667 putative structural protein YP_001725819.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001725820.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001725821.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_001725822.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001725823.1 KEGG: ssn:SSON_0754 biotin synthesis; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001725824.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001725825.1 YbhB; similar to rat and human kinase inhibitory proteins YP_001725826.1 PFAM: Insertion element protein; KEGG: sdy:SDY_4618 IS1 ORF1 YP_001725827.1 PFAM: Lambda phage regulatory protein CIII; KEGG: spt:SPA2420 hypothetical protein YP_001725828.1 PFAM: lambda Kil YP_001725829.1 PFAM: Host-nuclease inhibitor Gam; KEGG: sdy:SDY_1384 putative host-nuclease inhibitor protein Gam YP_001725830.1 TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: stt:t1923 bacteriophage recombination protein YP_001725831.1 PFAM: Exonuclease, phage-type; KEGG: sdy:SDY_1382 exonuclease YP_001725832.1 PFAM: protein of unknown function DUF1317 YP_001725833.1 PFAM: protein of unknown function DUF1382 YP_001725835.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: hit:NTHI1878 DnaK suppressor protein, bacteriophage PSP3 GP34 homolog YP_001725836.1 KEGG: sfv:SFV_0261 putative bacteriophage protein YP_001725837.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001725838.1 KEGG: mes:Meso_1109 hypothetical protein YP_001725839.1 KEGG: yps:YPTB1765 putative GP46 [bacteriophage N15] pir||T13133 protein GP46-...; Contains selenocysteine YP_001725840.1 KEGG: cps:CPS_0896 hypothetical protein YP_001725842.1 PFAM: Excisionase domain protein YP_001725843.1 PFAM: integrase family protein; integrase domain protein SAM domain protein; lambda integrase; KEGG: ssn:SSON_0746 putative integrase fragment YP_001725844.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_001725845.1 PFAM: aconitate hydratase domain protein; KEGG: sbo:SBO_0658 putative enzyme YP_001725846.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: sfv:SFV_0753 putative membrane pump protein YP_001725847.1 PFAM: protein of unknown function DUF453; KEGG: sfv:SFV_0752 hypothetical protein YP_001725848.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_0742 putative transcriptional regulator LysR-type YP_001725849.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_001725850.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001725851.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001725852.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001725853.1 with ModCB is involved in the high-affinity transport of molybdate YP_001725854.1 KEGG: sdy:SDY_0709 hypothetical protein YP_001725855.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001725856.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001725857.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ssn:SSON_0711 UDP-galactose-4-epimerase YP_001725858.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001725859.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001725860.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_001725861.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001725862.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001725863.1 KEGG: sfv:SFV_0587 putative homeobox protein YP_001725864.1 involved in zinc efflux across the cytoplasmic membrane YP_001725865.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: ssn:SSON_0703 required for NMN transport YP_001725866.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001725867.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001725868.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: sbo:SBO_0600 peptidoglycan-associated lipoprotein YP_001725869.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001725870.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001725871.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001725872.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001725873.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001725874.1 TIGRFAM: cyd operon protein YbgE; PFAM: Cyd operon protein YbgE; KEGG: sdy:SDY_0683 hypothetical protein YP_001725875.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sdy:SDY_0682 putative outer membrane lipoprotein YP_001725876.1 KEGG: ssn:SSON_0686 cytochrome d terminal oxidase polypeptide subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001725877.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sbo:SBO_0592 cytochrome d terminal oxidase, polypeptide subunit I YP_001725878.1 PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; KEGG: sfv:SFV_0604 putative sugar hydrolase YP_001725879.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001725880.1 regulates the succiny-lCoA synthetase operon YP_001725881.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001725882.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001725883.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001725884.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001725885.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001725886.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001725887.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: sdy:SDY_0660 succinate dehydrogenase, hydrophobic subunit YP_001725888.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: sfx:S0589 succinate dehydrogenase, cytochrome b556 YP_001725889.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001725890.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0670 putative fimbrial-like protein YP_001725891.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfx:S0592 putative outer membrane protein YP_001725892.1 PFAM: pili assembly chaperone; KEGG: ssn:SSON_0668 putative chaperone YP_001725893.1 KEGG: ssn:SSON_0667 hypothetical protein YP_001725894.1 TIGRFAM: membrane protein AbrB duplication; PFAM: putative ammonia monooxygenase; KEGG: ssn:SSON_0666 putative transport protein YP_001725895.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_001725896.1 PFAM: LamB/YcsF family protein; KEGG: sbo:SBO_0572 putative lactam utilization protein YP_001725897.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: sbo:SBO_0571 putative carboxylase YP_001725898.1 PFAM: Allophanate hydrolase subunit 1; KEGG: ssn:SSON_0662 putative carboxylase YP_001725899.1 PFAM: protein of unknown function DUF34; KEGG: sbo:SBO_0569 hypothetical protein YP_001725900.1 KEGG: sfx:S0601 putative transport protein; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001725901.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001725902.1 PFAM: Protein of unknown function DUF1722; KEGG: sfv:SFV_0628 hypothetical protein YP_001725903.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor YP_001725904.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor YP_001725906.1 PFAM: RHS protein; YD repeat-containing protein; KEGG: ssn:SSON_0655 RhsA protein in rhs element YP_001725908.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001725909.1 KEGG: sdy:SDY_0635 hypothetical protein YP_001725910.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001725911.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001725912.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001725913.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001725914.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001725915.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_001725916.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sbo:SBO_0554 ornithine decarboxylase isozyme, inducible YP_001725917.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001725918.1 KEGG: sbo:SBO_0552 hypothetical protein YP_001725919.1 KEGG: sbo:SBO_0551 putative pectinase YP_001725920.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001725921.1 negative modulator of the initiation of chromosome replication YP_001725922.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sbo:SBO_0548 hypothetical protein YP_001725923.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sdy:SDY_0625 hypothetical protein YP_001725924.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001725925.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001725926.1 KEGG: sfl:SF0611 hypothetical protein YP_001725927.1 PFAM: outer membrane porin; KEGG: sfx:S0623 hypothetical protein YP_001725928.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001725929.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001725930.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001725931.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001725932.1 PFAM: ROK family protein; KEGG: sdy:SDY_0610 transcriptional repressor of N-acetylglucosamine operon YP_001725933.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdy:SDY_0609 N-acetylglucosamine metabolism YP_001725934.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001725935.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001725936.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001725937.1 PFAM: PhoH family protein; KEGG: sdy:SDY_0596 putative ATP-binding protein in pho regulon YP_001725938.1 PFAM: protein of unknown function UPF0054; KEGG: sbo:SBO_0523 hypothetical protein YP_001725939.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: sdy:SDY_0594 putative transport protein YP_001725940.1 Transfers the fatty acyl group on membrane lipoproteins YP_001725941.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: Rhomboid family protein; KEGG: ssn:SSON_0610 hypothetical protein YP_001725942.1 PFAM: extracellular solute-binding protein family 3; KEGG: sdy:SDY_0592 putative periplasmic binding transport protein YP_001725943.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_0672 glutamate/aspartate transport system permease YP_001725944.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfx:S0650 glutamate/aspartate transport system permease YP_001725945.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_0606 ATP-binding protein of glutamate/aspartate transport system YP_001725946.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001725947.1 PFAM: Heat shock protein 70; KEGG: ssn:SSON_0604 putative DnaK protein YP_001725948.1 PFAM: heat shock protein DnaJ domain protein; KEGG: ssn:SSON_0603 hypothetical protein YP_001725949.1 PFAM: protein of unknown function DUF1266; KEGG: sfv:SFV_0678 putative tRNA ligase YP_001725950.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfv:SFV_0679 hypothetical protein YP_001725951.1 PFAM: heat shock protein DnaJ domain protein; KEGG: sbo:SBO_0510 putative enzyme of polynucleotide modification YP_001725952.1 PFAM: protein of unknown function DUF1266; KEGG: sbo:SBO_0509 hypothetical protein YP_001725953.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: ssn:SSON_0598 hypothetical protein YP_001725954.1 PFAM: protein of unknown function DUF1451; KEGG: sdy:SDY_0567 putative alpha helical protein YP_001725955.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001725956.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_001725957.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001725958.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001725959.1 TIGRFAM: alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase; KEGG: sfv:SFV_0688 PhpB YP_001725960.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: sfv:SFV_0689 hypothetical protein YP_001725961.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001725962.1 KEGG: sfv:SFV_0691 penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_001725963.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: sbo:SBO_0498 rod shape-determining membrane protein YP_001725964.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: ssn:SSON_0587 minor lipoprotein YP_001725965.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_001725966.1 PFAM: protein of unknown function DUF493; KEGG: sdy:SDY_0553 hypothetical protein YP_001725967.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001725968.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_0697 putative transcriptional regulator LysR-type YP_001725969.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001725970.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001725971.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001725972.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001725973.1 catalyzes the transfer of palmitate to lipid A YP_001725974.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_001725975.1 regulates the expression of citAB in citrate fermentation YP_001725976.1 PFAM: ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; KEGG: ssn:SSON_0572 putative sensor-type protein YP_001725977.1 KEGG: sbo:SBO_0483 citrate lyase synthetase; TIGRFAM: cytidyltransferase-related domain protein; citrate lyase ligase; PFAM: GCN5-related N-acetyltransferase; Citrate lyase ligase domain protein YP_001725978.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_001725979.1 KEGG: sbo:SBO_0481 citrate lyase beta chain, acyl lyase subunit; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase YP_001725980.1 KEGG: ssn:SSON_0567 citrate lyase alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit YP_001725981.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_001725982.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_001725983.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: sbo:SBO_0477 putative a membrane protein YP_001725984.1 PFAM: ribonuclease T2; KEGG: sfx:S0535 RNase I YP_001725985.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001725986.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sbo:SBO_0473 putative oxidoreductase YP_001725987.1 PFAM: UspA domain protein; KEGG: sdy:SDY_0542 hypothetical protein YP_001725988.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbo:SBO_0471 alkyl hydroperoxide reductase, F52a subunit YP_001725989.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_001725990.1 Involved in disulfide bond formation YP_001725991.1 PFAM: regulatory protein LysR; KEGG: sfv:SFV_0557 putative transcriptional regulator LysR-type YP_001725992.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: cko:CKO_02557 hypothetical protein YP_001725993.1 PFAM: ParB domain protein nuclease; KEGG: ssn:SSON_0553 hypothetical protein YP_001725994.1 catalyzes the transfer of an amino moiety YP_001725995.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_001725996.1 PFAM: protein of unknown function DUF466; KEGG: sdy:SDY_0530 hypothetical protein YP_001725997.1 PFAM: carbon starvation protein CstA; KEGG: sbo:SBO_0459 carbon starvation protein YP_001725998.1 PFAM: thioesterase superfamily protein; KEGG: sdy:SDY_0528 hypothetical protein YP_001725999.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_001726000.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: sfl:SF0509 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase YP_001726001.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_001726002.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: sdy:SDY_0524 isochorismate hydroxymutase 2 YP_001726003.1 with FepCDG is involved in the transport of ferric enterobactin YP_001726004.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_001726005.1 with FepBCG is involved in the transport of ferric enterobactin YP_001726006.1 with FepBCD is involved in the transport of ferric enterobactin YP_001726007.1 with FepBDE is involved in the transport of ferric enterobactin YP_001726008.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_001726009.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_001726010.1 PFAM: MbtH domain protein; KEGG: sbo:SBO_0446 putative cytoplasmic protein YP_001726011.1 PFAM: putative esterase; KEGG: sfv:SFV_0530 enterochelin esterase YP_001726012.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001726013.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: ssn:SSON_0533 enterochelin synthetase, component D YP_001726014.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1 YP_001726015.1 PFAM: Hok/gef cell toxic protein; KEGG: sfx:S0500 hypothetical protein YP_001726016.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_001726017.1 PFAM: protein of unknown function DUF1158; KEGG: sbo:SBO_0441 hypothetical protein YP_001726018.1 PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_0492 hypothetical protein YP_001726019.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001726020.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0528 putative transport YP_001726021.1 PFAM: amino acid permease-associated region; KEGG: sfv:SFV_0516 phenylalanine-specific transport system YP_001726022.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: ssn:SSON_0526 putative inner membrane component for iron transport YP_001726023.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001726024.1 KEGG: sfv:SFV_0506 hypothetical protein YP_001726025.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001726026.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001726027.1 KEGG: ssn:SSON_0521 putative 2-component sensor protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein YP_001726028.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ssn:SSON_0520 putative Vgr protein YP_001726029.1 PFAM: Domain of unknown function DUF1795; KEGG: ssn:SSON_0519 hypothetical protein YP_001726030.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; PAAR repeat-containing protein; KEGG: ssn:SSON_0517 rhs core protein with extension YP_001726033.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor YP_001726034.1 PFAM: General secretory system II protein E domain protein; KEGG: sfl:SF0470 bacteriophage N4 receptor, outer membrane protein YP_001726035.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ssn:SSON_0514 bacteriophage N4 receptor, outer membrane protein YP_001726036.1 KEGG: ssn:SSON_0513 hypothetical protein YP_001726037.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_0512 envelope protein YP_001726038.1 activates the production of the major fimbrae protein FimA YP_001726039.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0507 putative fimbrial-like protein YP_001726040.1 KEGG: ssn:SSON_0506 involved in fimbrial asembly YP_001726041.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: cko:CKO_02625 hypothetical protein YP_001726042.1 PFAM: pili assembly chaperone; KEGG: sfx:S0470 putative chaperone YP_001726043.1 PFAM: Fimbrial protein; KEGG: sfx:S0469 putative fimbrial-like protein YP_001726044.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001726045.1 KEGG: sdy:SDY_0280 hypothetical protein YP_001726046.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: sbo:SBO_0416 hypothetical protein YP_001726047.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001726048.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sfv:SFV_0483 peptidyl-prolyl cis-trans isomerase B (rotamase B) YP_001726049.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001726050.1 KEGG: sbo:SBO_0420 phosphoribosylaminoimidazole carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001726051.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001726052.1 KEGG: ssn:SSON_0497 putative carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_001726053.1 KEGG: sbo:SBO_0423 putative carboxylase YP_001726054.1 PFAM: protein of unknown function DUF1116; KEGG: stm:STM0530 putative cytoplasmic protein YP_001726055.1 multicopy suppressor of dominant negative ftsH mutations YP_001726056.1 TIGRFAM: ureidoglycolate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; KEGG: stm:STM0528 ureidoglycolate dehydrogenase YP_001726057.1 PFAM: transposase IS4 family protein; KEGG: sao:SAOUHSC_00778 hypothetical protein YP_001726058.1 TIGRFAM: allantoin catabolism protein; PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein; KEGG: sec:SC0565 putative glyoxylate utilization YP_001726059.1 PFAM: glycerate kinase; KEGG: stm:STM0525 glycerate kinase II YP_001726060.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: spt:SPA2199 putative permease protein YP_001726061.1 Plays a crucial role on both purine and pyrimidine metabolism YP_001726062.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sec:SC0561 putative allantoin permease YP_001726063.1 KEGG: stm:STM0519 tartronic semialdehyde reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding YP_001726064.1 KEGG: ssn:SSON_0503 glyoxylate-induced protein; TIGRFAM: hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel YP_001726065.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001726066.1 regulates operons involved in the utilization of allantoin YP_001726067.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001726068.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_001726069.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001726070.1 PFAM: protein of unknown function DUF214; KEGG: ssn:SSON_0485 putative oxidoreductase YP_001726071.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0396 putative ATP-binding component of a transport system YP_001726072.1 PFAM: lipolytic protein G-D-S-L family; KEGG: ssn:SSON_0484 acyl-CoA thioesterase I YP_001726073.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbo:SBO_0395 putative oxidoreductase YP_001726074.1 PFAM: Thioredoxin domain; KEGG: sdy:SDY_0407 putative thioredoxin-like protein YP_001726075.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_0480 putative metal resistance protein YP_001726076.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0392 putative ATP-binding component of a transport system YP_001726077.1 PFAM: band 7 protein; KEGG: sbo:SBO_0391 putative protease YP_001726078.1 PFAM: protein of unknown function DUF107; KEGG: sbo:SBO_0390 hypothetical protein YP_001726079.1 activator of copper-responsive regulon genes YP_001726080.1 PFAM: Spore germination protein; amino acid permease-associated region; KEGG: ssn:SSON_0475 putative amino acid/amine transport protein YP_001726081.1 catalyzes the formation of glutamate from glutamine YP_001726082.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sbo:SBO_0386 putative ATPase YP_001726083.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sbo:SBO_0385 hypothetical protein YP_001726084.1 PFAM: GumN family protein; KEGG: sfv:SFV_0455 putative ligase YP_001726085.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sfv:SFV_0454 hypothetical protein YP_001726086.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001726087.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0431 fosmidomycin resistance protein YP_001726088.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001726089.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_0377 inosine-guanosine kinase YP_001726090.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ssn:SSON_0463 putative lipase YP_001726091.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001726092.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001726093.1 molecular chaperone YP_001726094.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001726095.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_0448 hypothetical protein YP_001726096.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001726097.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001726098.1 PFAM: protein of unknown function DUF454; KEGG: sdy:SDY_0451 putative gene 58 YP_001726099.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_001726100.1 KEGG: sbo:SBO_0366 hypothetical protein YP_001726101.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001726102.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001726103.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_0450 acridine efflux pump YP_001726104.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_0362 acridine efflux pump YP_001726105.1 KEGG: sdy:SDY_0458 hypothetical protein YP_001726106.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_001726107.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: sdy:SDY_0460 putative transferase YP_001726108.1 KEGG: sdy:SDY_0461 hypothetical protein YP_001726109.1 PFAM: EAL domain protein; KEGG: sfv:SFV_0431 hypothetical protein YP_001726110.1 PFAM: protein of unknown function DUF1428; KEGG: sdy:SDY_0392 hypothetical protein YP_001726111.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: sdy:SDY_0391 hypothetical protein YP_001726112.1 KEGG: sfv:SFV_0427 glycoprotein/polysaccharide metabolism YP_001726113.1 KEGG: ssn:SSON_0440 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001726114.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ssn:SSON_0439 probable ammonium transporter YP_001726115.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001726116.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0344 putative ATP-binding component of a transport system YP_001726117.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_0385 ATP-binding component of a transport system YP_001726118.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: sbo:SBO_0341 putative LRP-like transcriptional regulator YP_001726119.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: ssn:SSON_0434 hypothetical protein YP_001726120.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001726121.1 PFAM: Insertion element protein; KEGG: sfx:S4666 IS1 orfA YP_001726122.1 TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: eca:ECA0499 putative capsular polysaccharide biosynthesis protein YP_001726123.1 KEGG: eca:ECA0500 putative capsular polysaccharide biosynthesis protein YP_001726124.1 PFAM: polysaccharide export protein; KEGG: eca:ECA0501 putative capsular polysaccharide export protein YP_001726125.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA0502 putative capsulatr polysaccharide biosynthesis protein YP_001726126.1 KEGG: eca:ECA0503 putative capsular polysaccharide bisynthesis protein YP_001726127.1 KEGG: eca:ECA0504 putative capsular polysaccharide bisynthesis protein YP_001726128.1 PFAM: glycosyl transferase family 2; KEGG: eca:ECA0505 probable capsular polysaccharide bisynthesis glycosyl transferase YP_001726129.1 PFAM: glycosyl transferase group 1; KEGG: eca:ECA0506 probable capsular polysaccharide bisynthesis glycosyl transferase YP_001726130.1 PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: eca:ECA0507 putative capsular polysaccharide bisynthesis glycosyl transferase YP_001726131.1 KEGG: eca:ECA0508 hypothetical protein YP_001726132.1 KEGG: eca:ECA0509 hypothetical protein YP_001726133.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase) YP_001726134.1 KEGG: pdi:BDI_0028 conserved hypothetical protein, putative glycosyltransferase YP_001726135.1 PFAM: Insertion element protein; KEGG: sfx:S4666 IS1 orfA YP_001726136.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_0339 hypothetical protein YP_001726137.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001726138.1 PFAM: thioesterase superfamily protein; KEGG: sbo:SBO_0337 hypothetical protein YP_001726139.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: sdy:SDY_0290 hypothetical protein YP_001726140.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: sbo:SBO_0335 putative protease maturation protein YP_001726141.1 histone-like DNA-binding protein YP_001726142.1 KEGG: ssn:SSON_0422 DNA-binding, ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001726143.1 binds and unfolds substrates as part of the ClpXP protease YP_001726144.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001726145.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001726146.1 KEGG: sdy:SDY_0297 hypothetical protein YP_001726147.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001726148.1 PFAM: Uncharacterized lipoprotein; KEGG: ssn:SSON_0417 putative polymerase/proteinase YP_001726149.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001726150.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: sbo:SBO_0326 cytochrome o ubiquinol oxidase subunit II YP_001726151.1 KEGG: ssn:SSON_0414 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase, subunit I; PFAM: cytochrome c oxidase subunit I YP_001726152.1 TIGRFAM: cytochrome o ubiquinol oxidase, subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: ssn:SSON_0413 cytochrome o ubiquinol oxidase subunit III YP_001726153.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: sbo:SBO_0323 cytochrome o ubiquinol oxidase subunit IV YP_001726154.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001726155.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_0303 putative transport protein YP_001726156.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001726157.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001726158.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: ssn:SSON_0401 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis YP_001726159.1 Required for the synthesis of the thiazole moiety YP_001726160.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001726161.1 PFAM: Polyprenyl synthetase; KEGG: sdy:SDY_0309 geranyltranstransferase YP_001726162.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001726163.1 PFAM: aldo/keto reductase; KEGG: sdy:SDY_0311 putative NAD(P)H-dependent xylose reductase YP_001726164.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001726165.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001726166.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001726167.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001726168.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_001726169.1 PFAM: ATP-cone domain protein; KEGG: sdy:SDY_0321 hypothetical protein YP_001726170.1 KEGG: ssn:SSON_0389 hypothetical protein YP_001726171.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: sdy:SDY_0323 nucleoside channel YP_001726172.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: sdy:SDY_0324 hypothetical protein YP_001726173.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001726174.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001726175.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001726176.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001726177.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001726178.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_001726179.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ssn:SSON_0380 maltodextrin glucosidase YP_001726180.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001726181.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: sdy:SDY_0336 branched chain amino acid transport system II carrier protein YP_001726182.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001726183.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_001726184.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001726185.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_001726186.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_001726187.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001726188.1 Required for efficient pilin antigenic variation YP_001726189.1 KEGG: sfv:SFV_0357 hypothetical protein YP_001726190.1 PFAM: protein of unknown function DUF1255; KEGG: sbo:SBO_0286 hypothetical protein YP_001726191.1 PFAM: AroM family protein; KEGG: sbo:SBO_0285 AroM YP_001726192.1 KEGG: sbo:SBO_0284 hypothetical protein YP_001726193.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001726194.1 PFAM: protein of unknown function DUF188; KEGG: sdy:SDY_0357 hypothetical protein YP_001726195.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001726196.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis YP_001726197.1 PFAM: PsiF repeat protein; KEGG: sbo:SBO_0279 PsiF YP_001726198.1 PFAM: Alkaline phosphatase; KEGG: sbo:SBO_0278 alkaline phosphatase YP_001726199.1 KEGG: ssn:SSON_0357 hypothetical protein YP_001726200.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001726201.1 KEGG: sdy:SDY_0366 hypothetical protein YP_001726202.1 KEGG: sbo:SBO_0274 hypothetical protein YP_001726203.1 PFAM: protein of unknown function DUF1615; KEGG: sbo:SBO_0273 hypothetical protein YP_001726204.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001726205.1 this protein has no known enzymatic function YP_001726206.1 KEGG: ssn:SSON_0350 hypothetical protein YP_001726207.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: cko:CKO_02805 hypothetical protein YP_001726208.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001726209.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001726210.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_0331 taurine transport system permease protein YP_001726211.1 Part of the ABC transporter complex tauABC involved in taurine import YP_001726212.1 with TauB and TauC is responsible for taurine uptake. YP_001726213.1 PFAM: LmbE family protein; KEGG: ssn:SSON_0340 hypothetical protein YP_001726214.1 PFAM: glycosyl transferase family 2; KEGG: aau:AAur_0762 glycosyl transferase, group 2 family domain protein YP_001726215.1 KEGG: ssn:SSON_0338 putative transferase YP_001726216.1 KEGG: ssn:SSON_0337 hypothetical protein YP_001726217.1 formaldehyde-induced negative regulator of the frmRAB operon YP_001726218.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_0335 alcohol dehydrogenase class III YP_001726219.1 KEGG: ssn:SSON_0334 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_001726220.1 KEGG: ssn:SSON_0333 nucleoprotein/polynucleotide-associated enzyme YP_001726221.1 TIGRFAM: benzoate transport; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_0332 putative transport protein YP_001726222.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001726223.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001726224.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_001726225.1 PFAM: alpha/beta hydrolase fold; KEGG: kpn:KPN_02120 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_001726226.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family YP_001726227.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_001726228.1 activator of 3-phenylpropionic acid catabolism YP_001726229.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_001726230.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001726231.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001726232.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown YP_001726233.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_001726234.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001726235.1 PFAM: carbonic anhydrase; KEGG: pen:PSEEN3600 carbonic anhydrase YP_001726236.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_001726237.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001726238.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sec:SC3271 putative purine-cytosine permease YP_001726239.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_001726240.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001726241.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001726242.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001726243.1 KEGG: cko:CKO_02831 hypothetical protein; TIGRFAM: propionate catabolism operon regulatory protein PrpR; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; Propionate catabolism activator domain protein; SMART: AAA ATPase YP_001726244.1 PFAM: protein of unknown function DUF1471; KEGG: cko:CKO_02832 hypothetical protein YP_001726245.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ssn:SSON_0302 putative cytochrome subunit of dehydrogenase YP_001726246.1 KEGG: ssn:SSON_0306 hypothetical protein YP_001726247.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_0308 putative oxidoreductase YP_001726248.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_001726249.1 PFAM: aspartate/glutamate/uridylate kinase; KEGG: ssn:SSON_0310 putative kinase YP_001726251.1 PFAM: protein of unknown function DUF1116; KEGG: ssn:SSON_0311 hypothetical protein YP_001726252.1 PFAM: FdrA family protein; KEGG: ssn:SSON_0312 putative oxidoreductase subunit YP_001726253.1 KEGG: ssn:SSON_0313 hypothetical protein YP_001726254.1 PFAM: Ankyrin; KEGG: ent:Ent638_3145 ankyrin YP_001726255.1 PFAM: protein of unknown function DUF1097; KEGG: ctc:CTC01779 glutathione-regulated potassium-efflux system protein YP_001726256.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_3146 transcriptional regulator, LysR family YP_001726257.1 PFAM: regulatory protein LuxR; EAL domain protein; KEGG: aha:AHA_3485 Rtn protein YP_001726258.1 proton-motive-force-driven choline transporter YP_001726259.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001726260.1 catalyzes the formation of betaine from betaine aldehyde YP_001726261.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001726262.1 KEGG: sfv:SFV_0321 hypothetical protein YP_001726263.1 PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0319 putative transporter YP_001726264.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0318 hypothetical protein YP_001726265.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: ssn:SSON_0318 putative dehydrogenase subunit YP_001726266.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_0319 putative AraC-type regulatory protein YP_001726267.1 Involved in disulfide oxidoreductase activity and electron transport YP_001726268.1 PFAM: protein of unknown function DUF417; KEGG: ssn:SSON_0322 hypothetical protein YP_001726269.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: stm:STM1671 putative regulatory protein YP_001726270.1 PFAM: Ig domain protein group 1 domain protein; KEGG: ypi:YpsIP31758_0608 putative invasin YP_001726271.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001726272.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001726273.1 PFAM: regulatory protein LuxR; KEGG: sbo:SBO_0225 putative regulator YP_001726274.1 KEGG: sbo:SBO_0226 hypothetical protein YP_001726275.1 KEGG: sbo:SBO_0227 hypothetical protein YP_001726276.1 KEGG: kpn:KPN_00293 putative enzyme YP_001726277.1 KEGG: kpn:KPN_00294 putative receptor YP_001726278.1 KEGG: kpn:KPN_00295 hypothetical protein YP_001726279.1 PFAM: protein of unknown function UPF0153; KEGG: esa:ESA_01555 hypothetical protein YP_001726280.1 PFAM: protein of unknown function DUF1440; KEGG: ent:Ent638_2282 protein of unknown function DUF1440 YP_001726281.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: esa:ESA_04143 hypothetical protein YP_001726282.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: esa:ESA_04145 hypothetical protein YP_001726283.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: esa:ESA_04146 hypothetical protein YP_001726284.1 PFAM: protein of unknown function DUF182; KEGG: esa:ESA_04147 hypothetical protein YP_001726285.1 KEGG: smd:Smed_5891 transcriptional regulator, LysR family YP_001726286.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001726287.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001726288.1 PFAM: porin Gram-negative type; KEGG: sbo:SBO_0247 outer membrane pore protein E YP_001726289.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001726290.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001726291.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001726292.1 KEGG: sdy:SDY_0480 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001726293.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001726294.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: sfv:SFV_0298 hypothetical protein YP_001726295.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001726296.1 PFAM: OmpA/MotB domain protein; KEGG: sdy:SDY_0484 putative motility protein YP_001726297.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001726298.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001726299.1 PFAM: flagellar basal body-associated protein FliL; KEGG: cvi:CV_2991 hypothetical protein YP_001726300.1 PFAM: flagellar hook-length control protein; KEGG: cko:CKO_02859 hypothetical protein YP_001726302.1 PFAM: flagellar protein FliS; KEGG: cko:CKO_02862 hypothetical protein YP_001726303.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: vha:VIBHAR_04956 flagellar capping protein YP_001726304.1 PFAM: flagellin domain protein; KEGG: pmy:Pmen_0196 flagellin domain protein YP_001726305.1 PFAM: transcriptional regulator domain protein; KEGG: cko:CKO_02869 hypothetical protein YP_001726306.1 KEGG: cko:CKO_02871 hypothetical protein YP_001726307.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: pmy:Pmen_0216 flagellar hook-associated protein 3 YP_001726308.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cko:CKO_02873 hypothetical protein YP_001726309.1 KEGG: yps:YPTB3332 putative flagellar protein YP_001726310.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001726311.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH YP_001726312.1 makes up the distal portion of the flagellar basal body rod YP_001726313.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001726314.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: pmy:Pmen_0209 flagellar basal body FlaE domain protein YP_001726315.1 PFAM: flagellar hook capping protein; KEGG: cko:CKO_02880 hypothetical protein YP_001726316.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001726317.1 TIGRFAM: flagellar basal-body rod protein FlgB; KEGG: cko:CKO_02882 hypothetical protein YP_001726318.1 TIGRFAM: flagella basal body P-ring formation protein FlgA; PFAM: SAF domain protein; KEGG: cko:CKO_02883 hypothetical protein YP_001726319.1 PFAM: Anti-sigma-28 factor FlgM family protein YP_001726320.1 KEGG: cko:CKO_02886 hypothetical protein YP_001726321.1 KEGG: cko:CKO_02891 hypothetical protein YP_001726322.1 PFAM: glycosyl transferase family 2; KEGG: cko:CKO_02892 hypothetical protein YP_001726323.1 TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: nca:Noca_1691 cytidyltransferase-related domain YP_001726324.1 TIGRFAM: flagellar export protein FliJ; KEGG: cko:CKO_02893 hypothetical protein YP_001726325.1 KEGG: cko:CKO_02894 hypothetical protein; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase YP_001726326.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001726327.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001726328.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001726329.1 PFAM: flagellar hook-basal body complex protein FliE; KEGG: vpa:VPA1537 putative flagellar hook-basal body complex protein YP_001726330.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; KEGG: ypi:YpsIP31758_0629 sigma-54 dependent transcriptional regulator YP_001726331.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: cko:CKO_02900 hypothetical protein YP_001726332.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: cko:CKO_02901 hypothetical protein YP_001726333.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001726334.1 PFAM: export protein FliQ family 3; KEGG: yps:YPTB3354 putative flagellar assembly/export protein, fliQ YP_001726335.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: cko:CKO_02904 hypothetical protein YP_001726336.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001726337.1 PFAM: type III secretion FHIPEP protein; KEGG: ssn:SSON_0273 flagellar biosynthesis YP_001726338.1 KEGG: ssn:SSON_0271 hypothetical protein YP_001726339.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_0269 putative lipoprotein YP_001726340.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: ssn:SSON_0268 damage-inducible protein J YP_001726341.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sdy:SDY_0251 hypothetical protein YP_001726342.1 PFAM: protein of unknown function DUF949; KEGG: sdy:SDY_0250 hypothetical protein YP_001726343.1 PFAM: glutamine amidotransferase class-II; KEGG: sdy:SDY_0249 putative amidotransferase YP_001726344.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001726345.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001726346.1 inactivates vertebrate C-type lysozyme YP_001726347.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbo:SBO_0208 putative amidase-type enzyme YP_001726348.1 KEGG: dac:Daci_2522 conserved hypothetical protein YP_001726349.1 PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_001726350.1 PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family YP_001726351.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_4359 ISEhe3 orfA YP_001726352.1 KEGG: bxe:Bxe_C0741 putative transposase IS30 YP_001726353.1 PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2 YP_001726354.1 KEGG: kpn:KPN_pKPN3p05933 probable copper-binding protein YP_001726355.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: esa:ESA_04254 hypothetical protein YP_001726356.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: kpn:KPN_pKPN3p05937 transcriptional regulatory protein PcoR YP_001726357.1 PFAM: copper resistance D domain protein; KEGG: kpn:KPN_pKPN3p05938 copper resistant protein PcoD YP_001726358.1 PFAM: copper resistance protein CopC; KEGG: kpn:KPN_pKPN3p05939 copper resistant protein PcoC YP_001726359.1 PFAM: copper resistance B precursor; KEGG: kpn:KPN_pKPN3p05940 copper resistant protein PcoB YP_001726360.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: kpn:KPN_pKPN3p05941 copper resistant protein PcoA YP_001726361.1 KEGG: shn:Shewana3_4304 hypothetical protein YP_001726362.1 PFAM: peptidase M23B; KEGG: shn:Shewana3_4303 peptidase M23B YP_001726363.1 KEGG: esa:ESA_04246 hypothetical protein YP_001726364.1 KEGG: spc:Sputcn32_0264 heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein YP_001726365.1 PFAM: protein of unknown function DUF411; KEGG: kpn:KPN_pKPN3p05946 exported protein (silver resistance) YP_001726366.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: esa:ESA_04242 hypothetical protein YP_001726367.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001726368.1 KEGG: spc:Sputcn32_0260 periplasmic copper-binding protein YP_001726369.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001726370.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001726371.1 KEGG: esa:ESA_04237 hypothetical protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein YP_001726372.1 KEGG: kpn:KPN_pKPN3p05952 silver binding protein precursor SilE YP_001726373.1 PFAM: protein of unknown function DUF305; KEGG: esa:ESA_04235 hypothetical protein YP_001726374.1 PFAM: putative transposase YhgA family protein; KEGG: stm:PSLT051 putative cytoplasmic protein YP_001726375.1 PFAM: GTP-binding protein HSR1-related; KEGG: ypi:YpsIP31758_0759 putative GTPase YP_001726376.1 KEGG: ypi:YpsIP31758_0758 transcriptional regulator YP_001726377.1 KEGG: ypi:YpsIP31758_0757 hypothetical protein YP_001726380.1 KEGG: ypi:YpsIP31758_0756 hypothetical protein YP_001726381.1 KEGG: sfx:S3197 hypothetical protein YP_001726382.1 KEGG: ypp:YPDSF_4148 hypothetical protein YP_001726383.1 PFAM: protein of unknown function DUF932; KEGG: sfx:S3199 hypothetical protein YP_001726384.1 PFAM: Antirestriction protein; KEGG: sdy:SDY_4589 hypothetical protein YP_001726385.1 PFAM: DNA repair protein RadC; KEGG: yps:YPTB3868 hypothetical protein YP_001726386.1 PFAM: protein of unknown function DUF987; KEGG: sfx:S3202 hypothetical protein YP_001726387.1 PFAM: YagBYeeUYfjZ family protein; KEGG: sfx:S3203 putative structural protein YP_001726388.1 PFAM: protein of unknown function DUF1219; KEGG: sdy:SDY_1009 hypothetical protein YP_001726389.1 KEGG: sdy:SDY_1008 hypothetical protein YP_001726390.1 PFAM: protein of unknown function DUF957; KEGG: sfl:SF3001 hypothetical protein YP_001726391.1 3'-5' exonuclease of DNA polymerase III YP_001726392.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001726393.1 PFAM: Methyltransferase type 11; KEGG: ssn:SSON_0227 hypothetical protein YP_001726394.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_001726395.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001726396.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ssn:SSON_0224 putative biotin synthesis protein YP_001726397.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sbo:SBO_0198 hypothetical protein YP_001726398.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_0222 putative transcriptional regulator LysR-type YP_001726399.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001726400.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001726401.1 part of the metNIQ transport system for methionine YP_001726402.1 part of the MetNIQ methionine uptake system YP_001726403.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sbo:SBO_0186 putative lipoprotein YP_001726404.1 KEGG: sdy:SDY_0215 regulator in colanic acid synthesis YP_001726405.1 PFAM: protein of unknown function UPF0066; KEGG: ssn:SSON_0209 hypothetical protein YP_001726406.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001726407.1 KEGG: ssn:SSON_0207 hypothetical protein YP_001726408.1 PFAM: copper resistance lipoprotein NlpE; KEGG: ssn:SSON_0206 copper homeostasis protein YP_001726409.1 PFAM: Class I peptide chain release factor; KEGG: sbo:SBO_0180 hypothetical protein YP_001726410.1 PFAM: YaeQ family protein; KEGG: sbo:SBO_0179 hypothetical protein YP_001726411.1 PFAM: protein of unknown function UPF0253; KEGG: sdy:SDY_0208 putative cytoplasmic protein YP_001726412.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_001726413.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_001726414.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sbo:SBO_0175 hypothetical protein YP_001726415.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ssn:SSON_0199 lysine decarboxylase 2, constitutive YP_001726416.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001726417.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001726418.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001726419.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001726420.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001726421.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001726422.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001726423.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: sdy:SDY_0194 histone-like protein YP_001726424.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001726425.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001726426.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001726427.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001726428.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001726429.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001726430.1 Catalyzes the phosphorylation of UMP to UDP YP_001726431.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001726432.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001726433.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001726434.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001726435.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001726436.1 PFAM: metallophosphoesterase; KEGG: sbo:SBO_0153 hypothetical protein YP_001726437.1 KEGG: sdy:SDY_0181 putative structural protein YP_001726438.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_001726439.1 protease Do; required at high temperature; degrades damaged proteins YP_001726440.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001726441.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001726442.1 solute binding component of the vitamin B12 transport system BtuCDF YP_001726443.1 PFAM: protein of unknown function UPF0126; KEGG: sbo:SBO_0146 hypothetical protein YP_001726444.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001726445.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001726446.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001726447.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001726448.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001726449.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001726450.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_001726451.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001726452.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001726453.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: ssn:SSON_0159 hypothetical protein YP_001726454.1 Regulatory factor involved in maltose metabolism YP_001726455.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: sdy:SDY_0161 DnaK suppressor protein YP_001726456.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001726457.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001726458.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_001726459.1 PFAM: Fimbrial protein; KEGG: stt:t0190 putative fimbrial protein YP_001726460.1 PFAM: pili assembly chaperone; KEGG: sbo:SBO_0126 probable pilin chaperone YP_001726461.1 similar to the fimbrial usher protein PapC YP_001726462.1 KEGG: stt:t0187 putative fimbrial protein YP_001726463.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0146 putative fimbrial protein YP_001726464.1 PFAM: Fimbrial protein; KEGG: ssn:SSON_0145 putative fimbrial protein YP_001726465.1 PFAM: Fimbrial protein; KEGG: cko:CKO_03237 hypothetical protein YP_001726466.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001726467.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001726468.1 PFAM: putative transposase YhgA family protein; KEGG: sfv:SFV_0122 hypothetical protein YP_001726469.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001726470.1 PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_0138 hypothetical protein YP_001726471.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sbo:SBO_0118 putative PTS enzyme II B component YP_001726472.1 PFAM: ABC-2 type transporter; KEGG: sdy:SDY_0037 hypothetical protein YP_001726473.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_0135 putative ATP-binding component of a transport system YP_001726474.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_001726475.1 KEGG: sdy:SDY_0034 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001726476.1 KEGG: sbo:SBO_0113 glucose dehydrogenase; TIGRFAM: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; PFAM: Pyrrolo-quinoline quinone YP_001726477.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001726478.1 KEGG: sdy:SDY_0029 hypothetical protein YP_001726479.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001726480.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001726481.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_0026 hypothetical protein YP_001726482.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001726483.1 KEGG: sfv:SFV_0108 hypothetical protein YP_001726484.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001726485.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001726486.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001726487.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001726488.1 PFAM: amino acid permease-associated region; KEGG: sfx:S0111 aromatic amino acid transport protein YP_001726489.1 involved in regulation of beta-lactamase; putative signaling protein YP_001726490.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sdy:SDY_0140 regulates AmpC YP_001726491.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001726492.1 KEGG: ssn:SSON_0116 prelipin peptidase dependent protein YP_001726493.1 PFAM: type II secretion system protein E; KEGG: sdy:SDY_0137 HofB YP_001726494.1 PFAM: type II secretion system protein; KEGG: ssn:SSON_0114 putative integral membrane protein YP_001726495.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001726496.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001726497.1 PFAM: protein of unknown function DUF1342; KEGG: ssn:SSON_0110 hypothetical protein YP_001726498.1 PFAM: protein of unknown function DUF329; KEGG: sdy:SDY_0131 hypothetical protein YP_001726499.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: ssn:SSON_0107 7,8-dihydro-8-oxoguanine-triphosphatase YP_001726500.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001726501.1 secM translational pause allows for the initiation of secA translation YP_001726502.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001726503.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001726504.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001726505.1 involved in septum formation YP_001726506.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001726507.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001726508.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001726509.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001726510.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001726511.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001726512.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_0074 D-alanine:D-alanine-adding enzyme YP_001726513.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001726514.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: sdy:SDY_0114 penicillin-binding protein 3 YP_001726515.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001726516.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: sbo:SBO_0070 putative apolipoprotein YP_001726517.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001726518.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001726520.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001726521.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_001726522.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_001726523.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis YP_001726524.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001726525.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001726526.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001726527.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001726528.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0067 putative transport protein YP_001726529.1 activates sgrS under glucose-phosphate stress conditions YP_001726530.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001726531.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001726532.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001726533.1 PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_0052 hypothetical protein YP_001726534.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001726535.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001726536.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001726537.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001726538.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001726539.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001726540.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_001726541.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001726542.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001726543.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001726544.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001726545.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001726546.1 protein associated with Co2+ and Mg2+ efflux YP_001726547.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001726548.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001726549.1 transport system that facilitates potassium-efflux YP_001726550.1 Required for full activity of KefC, a potassium-proton antiporter YP_001726551.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sfv:SFV_0039 putative transport protein YP_001726552.1 KEGG: sdy:SDY_0066 putative ferredoxin YP_001726553.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_001726554.1 involved in electron transfer during carnitine metabolism YP_001726555.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001726556.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001726557.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001726558.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001726559.1 PFAM: AMP-dependent synthetase and ligase; KEGG: ssn:SSON_0043 probable crotonobetaine/carnitine-CoA ligase YP_001726560.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001726561.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_001726562.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons YP_001726563.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001726564.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001726565.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001726566.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001726567.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: sbo:SBO_0027 probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase YP_001726568.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001726569.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001726570.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001726571.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001726572.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001726574.1 KEGG: ssn:SSON_0023 hypothetical protein YP_001726575.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001726576.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001726577.1 PFAM: Hok/gef cell toxic protein; KEGG: sbo:SBO_0017 Gef YP_001726578.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1 YP_001726579.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001726580.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001726581.1 KEGG: ssn:SSON_0013 hypothetical protein YP_001726582.1 PFAM: protein of unknown function UPF0174; KEGG: ssn:SSON_0012 putative oxidoreductase YP_001726583.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: ssn:SSON_0011 hypothetical protein YP_001726584.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001726585.1 KEGG: sbo:SBO_0009 transaldolase B; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001726586.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdy:SDY_0007 inner membrane transport protein YP_001726587.1 PFAM: protein of unknown function DUF328; KEGG: sdy:SDY_0006 hypothetical protein YP_001726588.1 KEGG: ssn:SSON_0005 hypothetical protein YP_001726589.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001726590.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001726591.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001726592.1 member of the SPOUT superfamily of methyltransferases YP_001726593.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sdy:SDY_4662 negative response regulator of genes in aerobic pathways YP_001726594.1 PFAM: Inner membrane CreD family protein; KEGG: sfx:S4703 inner membrane protein CreD YP_001726595.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001726596.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001726597.1 PFAM: CreA family protein; KEGG: sdy:SDY_4658 hypothetical protein YP_001726598.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: sbo:SBO_4459 right origin-binding protein YP_001726599.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001726600.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001726601.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001726602.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001726603.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001726604.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001726605.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001726606.1 catalyzes the formation of serine from O-phosphoserine YP_001726607.1 KEGG: sbo:SBO_4450 hypothetical protein YP_001726608.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_001726609.1 PFAM: helix-turn-helix domain protein; KEGG: sfv:SFV_4419 hypothetical protein YP_001726610.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001726611.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001726612.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001726613.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001726614.1 KEGG: ssn:SSON_4531 hypothetical protein YP_001726615.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: sfv:SFV_4413 putative activating enzyme YP_001726616.1 PFAM: TatD-related deoxyribonuclease; KEGG: ssn:SSON_4529 Mg-dependent DNase YP_001726617.1 PFAM: Patatin; KEGG: ssn:SSON_4528 hypothetical protein YP_001726618.1 PFAM: protein of unknown function DUF1328; KEGG: ssn:SSON_4527 hypothetical protein YP_001726619.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ssn:SSON_4526 hyperosmotically inducible periplasmic protein YP_001726620.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001726621.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001726622.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001726623.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001726624.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001726625.1 PFAM: protein of unknown function DUF1435; KEGG: sbo:SBO_4428 putative inner membrane protein YP_001726626.1 PFAM: ferric iron reductase; KEGG: sbo:SBO_4427 hypothetical protein YP_001726627.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_001726628.1 PFAM: regulatory protein LuxR; KEGG: sbo:SBO_4425 putative regulator YP_001726629.1 PFAM: protein of unknown function DUF1212; KEGG: sfv:SFV_4395 putative structural protein YP_001726630.1 KEGG: sfv:SFV_4394 hypothetical protein YP_001726631.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_001726632.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_001726633.1 KEGG: ssn:SSON_4506 putative glycoprotein/receptor YP_001726634.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_001726635.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_4504 putative oxidoreductase YP_001726636.1 PFAM: GntR domain protein; KEGG: eca:ECA4381 putative DNA-binding protein YP_001726637.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_4387 putative transport protein YP_001726638.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sfv:SFV_4386 methyl-accepting chemotaxis protein I YP_001726639.1 TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein MarR; KEGG: sfv:SFV_4385 homoprotocatechuate degradative operon repressor YP_001726640.1 KEGG: sbo:SBO_4412 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomerase; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase YP_001726641.1 TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: sbo:SBO_4411 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase YP_001726642.1 KEGG: sbo:SBO_4410 homoprotocatechuate dyoxygenase; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B YP_001726643.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: sfx:S4651 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_001726644.1 KEGG: ssn:SSON_4495 2-oxo-hept-3-ene-1,7-dioate hydratase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase YP_001726645.1 KEGG: sbo:SBO_4407 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase YP_001726646.1 TIGRFAM: 4-hydroxyphenylacetate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4406 putative 4-hydroxyphenylacetate permease YP_001726647.1 TIGRFAM: 4-hydroxyphenylacetate catabolism regulatory protein HpaA; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; KEGG: kpn:KPN_04781 4-hydroxyphenylacetate catabolism YP_001726648.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: ssn:SSON_4489 4-hydroxyphenylacetate 3-monooxygenase YP_001726649.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit; PFAM: flavin reductase domain protein FMN-binding; KEGG: sbo:SBO_4403 4-hydroxyphenylacetate 3-monooxygenase coupling protein YP_001726650.1 PFAM: carbon starvation protein CstA; KEGG: sdy:SDY_4607 putative carbon starvation protein YP_001726651.1 PFAM: protein of unknown function DUF466; KEGG: sdy:SDY_4606 hypothetical protein YP_001726652.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sfv:SFV_4371 hypothetical protein YP_001726653.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: gka:GK3294 hypothetical protein YP_001726654.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2 YP_001726655.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1 YP_001726656.1 PFAM: restriction modification system DNA specificity domain; KEGG: sfx:S4635 hypothetical protein YP_001726657.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_001726658.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: pcr:Pcryo_1606 protein of unknown function DUF1524 RloF YP_001726659.1 PFAM: protein of unknown function DUF1127; KEGG: sdy:SDY_4602 hypothetical protein YP_001726660.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sdy:SDY_4601 putative regulator YP_001726661.1 PFAM: putative transposase YhgA family protein; KEGG: sdy:SDY_4600 hypothetical protein YP_001726662.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4389 putative transport protein YP_001726663.1 PFAM: protein of unknown function DUF445; KEGG: sbo:SBO_4388 hypothetical protein YP_001726664.1 KEGG: kpn:KPN_04766 hypothetical protein YP_001726665.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: cko:CKO_03458 hypothetical protein YP_001726666.1 TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: sdy:SDY_4596 putative enzyme YP_001726667.1 KEGG: sbo:SBO_4385 hypothetical protein YP_001726668.1 PFAM: SdiA-regulated domain protein; KEGG: sbo:SBO_4384 hypothetical protein YP_001726669.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: sbo:SBO_4383 putative transport protein YP_001726670.1 PFAM: nucleoside recognition domain protein; KEGG: sfx:S4444 hypothetical protein YP_001726671.1 PFAM: nucleoside recognition domain protein; KEGG: sbo:SBO_4380 hypothetical protein YP_001726672.1 KEGG: sbo:SBO_4379 isoaspartyl dipeptidase; TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; Amidohydrolase 3 YP_001726673.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_4199 putative transcriptional regulator LysR-type YP_001726674.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_001726675.1 KEGG: ssn:SSON_4480 hypothetical protein YP_001726676.1 regulates the expression of uxuBA YP_001726677.1 PFAM: Mannitol dehydrogenase domain; KEGG: ssn:SSON_4478 D-mannonate oxidoreductase YP_001726678.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001726679.1 PFAM: Fimbrial protein ; FimH mannose-binding domain protein; KEGG: sfv:SFV_4206 FimH protein precursor YP_001726680.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1 YP_001726681.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2 YP_001726682.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfv:SFV_4229 putative oxidoreductase YP_001726683.1 PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: ssn:SSON_4448 hypothetical protein YP_001726684.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sdy:SDY_4286 hypothetical protein YP_001726685.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sbo:SBO_4179 hypothetical protein YP_001726686.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001726687.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001726688.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001726689.1 PFAM: protein of unknown function DUF898 transmembrane; KEGG: sfx:S4493 hypothetical protein YP_001726690.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfl:SF4233 putative acetyltransferase YP_001726691.1 PFAM: protein of unknown function DUF1260; KEGG: sdy:SDY_4277 hypothetical protein YP_001726692.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_001726693.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_4270 hypothetical protein YP_001726694.1 PFAM: regulatory protein TetR; KEGG: sfv:SFV_4244 hypothetical protein YP_001726695.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sfv:SFV_4245 putative oxidoreductase YP_001726696.1 PFAM: Endoribonuclease L-PSP; KEGG: ssn:SSON_4428 hypothetical protein YP_001726697.1 PFAM: PyrBI operon leader peptide; KEGG: sdy:SDY_4265 pyrBI operon leader peptide YP_001726698.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001726699.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001726700.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_4262 hypothetical protein YP_001726701.1 P-type ATPase involved in magnesium influx YP_001726702.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_001726703.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001726704.1 KEGG: sfx:S4513 trehalase 6-P hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_001726705.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001726706.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001726707.1 PFAM: cytochrome b562; KEGG: sfv:SFV_4255 cytochrome b(562) YP_001726708.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001726709.1 PFAM: protein of unknown function DUF615; KEGG: ssn:SSON_4415 putative alpha helix protein YP_001726710.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_4213 putative ligase YP_001726711.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001726712.1 membrane component of a putative sugar ABC transporter system YP_001726713.1 PFAM: inner-membrane translocator; KEGG: ssn:SSON_4411 putative transport system permease protein YP_001726714.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_4410 putative ATP-binding component of a transport system YP_001726715.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sbo:SBO_4218 putative LacI-type transcriptional regulator YP_001726716.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001726717.1 PFAM: AIG2 family protein; KEGG: sdy:SDY_4459 hypothetical protein YP_001726718.1 PFAM: protein of unknown function DUF490; KEGG: ssn:SSON_4406 hypothetical protein YP_001726719.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: sbo:SBO_4223 hypothetical protein YP_001726720.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001726721.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sdy:SDY_4455 putative transport protein YP_001726722.1 PFAM: protein of unknown function DUF1107; KEGG: sdy:SDY_4454 hypothetical protein YP_001726723.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_4227 hypothetical protein YP_001726724.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001726725.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001726726.1 PFAM: helix-turn-helix HxlR type; KEGG: sbo:SBO_4232 hypothetical protein YP_001726727.1 PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sbo:SBO_4231 putative oxidoreductase YP_001726728.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4395 putative transmembrane subunit YP_001726729.1 Involved in anaerobic NO protection and iron metabolism YP_001726730.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001726731.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001726732.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sdy:SDY_4376 hypothetical protein YP_001726733.1 PFAM: regulatory protein TetR; KEGG: sfv:SFV_4282 hypothetical protein YP_001726734.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001726735.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sbo:SBO_4242 hypothetical protein YP_001726736.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sbo:SBO_4243 hypothetical protein YP_001726737.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rle:RL1831 putative oxidoreductase/dehydrogenase flavoprotein binding YP_001726738.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: plu:plu0173 hypothetical protein YP_001726739.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ppr:PBPRB1879 C4-dicarboxylate transport system, putative integral membrane protein YP_001726740.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: ssn:SSON_4387 putative dicarboxylate-binding periplasmic protein YP_001726741.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001726742.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001726743.1 binds single-stranded DNA at the primosome assembly site YP_001726744.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001726745.1 PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_4255 hypothetical protein YP_001726746.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001726747.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_001726748.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_001726749.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001726750.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001726751.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001726752.1 KEGG: ssn:SSON_4374 hypothetical protein YP_001726753.1 negative regulator of ulaG and ulaABCDEF YP_001726754.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001726755.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_001726756.1 PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_4267 hypothetical protein YP_001726757.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_001726758.1 PFAM: glutathionylspermidine synthase; KEGG: sfx:S4608 putative synthetase/amidase YP_001726759.1 PFAM: protein of unknown function DUF1190; KEGG: sfv:SFV_4341 hypothetical protein YP_001726760.1 PFAM: protein of unknown function DUF350; KEGG: sbo:SBO_4271 hypothetical protein YP_001726761.1 KEGG: sbo:SBO_4272 hypothetical protein YP_001726762.1 PFAM: PspA/IM30 family protein; KEGG: sbo:SBO_4273 putative alpha helical protein YP_001726763.1 KEGG: stm:STM4370 putative cytoplasmic protein YP_001726764.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001726765.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001726766.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001726767.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001726768.1 KEGG: sdy:SDY_4413 hypothetical protein YP_001726769.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001726770.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001726771.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001726772.1 Stimulates the elongation of poly(A) tails YP_001726773.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001726774.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001726775.1 PFAM: cell wall hydrolase/autolysin; KEGG: ssn:SSON_4354 N-acetylmuramoyl-L-alanine amidase II YP_001726776.1 possibly involved in cell wall synthesis YP_001726777.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: sbo:SBO_4290 hypothetical protein YP_001726778.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: sfv:SFV_4325 hypothetical protein YP_001726779.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001726780.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001726781.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001726782.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_4298 putative periplasmic binding protein YP_001726783.1 KEGG: stm:STM4346 putative inner membrane protein YP_001726784.1 KEGG: spt:SPA4163 hypothetical protein YP_001726785.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_4434 putative transport YP_001726786.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001726787.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001726788.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001726789.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001726790.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001726791.1 PFAM: beta-lactamase; KEGG: sbo:SBO_4306 beta-lactamase YP_001726792.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001726793.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_001726794.1 PFAM: Entericidin EcnAB; KEGG: ssn:SSON_4333 putative toxin of osmotically regulated toxin-antitoxin system associated with programmed cell death YP_001726795.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex YP_001726796.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001726797.1 KEGG: sfx:S4569 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_001726798.1 KEGG: sbo:SBO_4311 hypothetical protein YP_001726799.1 KEGG: sdy:SDY_4450 hypothetical protein YP_001726800.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001726801.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001726802.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001726803.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001726804.1 catalyzes the formation of fumarate from aspartate YP_001726805.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001726806.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_001726807.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001726808.1 PFAM: regulatory protein TetR; KEGG: ssn:SSON_4318 hypothetical protein YP_001726809.1 PFAM: integrase family protein; KEGG: sfx:S4822 putative P4-type integrase YP_001726810.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001726811.1 PFAM: UvrD/REP helicase; KEGG: mgm:Mmc1_1352 UvrD/REP helicase YP_001726812.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: mgm:Mmc1_1353 DEAD/DEAH box helicase domain protein YP_001726813.1 KEGG: mgm:Mmc1_1354 hypothetical protein YP_001726814.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; KEGG: mgm:Mmc1_1355 helicase domain protein YP_001726815.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: lpf:lpl2494 hypothetical protein YP_001726816.1 KEGG: lpf:lpl2493 hypothetical protein YP_001726817.1 KEGG: hso:HS_0451 hypothetical protein YP_001726818.1 KEGG: hso:HS_0452 hypothetical protein YP_001726819.1 KEGG: hso:HS_0453 hypothetical protein YP_001726820.1 KEGG: sfv:SFV_4217 hypothetical protein YP_001726821.1 PFAM: transposase IS4 family protein; KEGG: kpn:KPN_pKPN3p05895 IS5 transposase YP_001726822.1 PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein YP_001726823.1 regulates the cadBA operon YP_001726824.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_001726825.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpn:KPN_00500 lysine decarboxylase 1 YP_001726826.1 KEGG: ssn:SSON_4307 putative peptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001726827.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001726828.1 KEGG: spt:SPA1272 putative inner membrane protein YP_001726829.1 KEGG: sdy:SDY_4240 hypothetical protein YP_001726830.1 PFAM: protein of unknown function DUF1271; KEGG: ssn:SSON_4303 hypothetical protein YP_001726831.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_001726832.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_001726833.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001726834.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sdy:SDY_4231 fumarase B YP_001726835.1 KEGG: sbo:SBO_4325 hypothetical protein YP_001726836.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; KEGG: sfv:SFV_4110 melibiose permease II YP_001726837.1 PFAM: glycoside hydrolase family 4; KEGG: ssn:SSON_4294 alpha-galactosidase YP_001726838.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_4145 regulator of melibiose operon YP_001726839.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sdy:SDY_4094 biodegradative arginine decarboxylase YP_001726840.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_4097 putative AraC-type regulatory protein YP_001726841.1 PFAM: amino acid permease-associated region; KEGG: ssn:SSON_4290 putative amino acid/amine transport protein, cryptic YP_001726842.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001726843.1 response regulator in two-component regulatory system with BasS YP_001726844.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sbo:SBO_4139 sensor protein for BasR YP_001726845.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; Osmosensory transporter coiled coil; KEGG: sdy:SDY_4102 proline permease II YP_001726846.1 KEGG: sfv:SFV_4120 hypothetical protein YP_001726847.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: sdy:SDY_4109 hypothetical protein YP_001726848.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: sbo:SBO_4132 hypothetical protein YP_001726849.1 KEGG: ssn:SSON_4281 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001726850.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; phosphonate ABC transporter, periplasmic phosphonate binding protein; KEGG: sbo:SBO_4130 periplasmic binding protein component of Pn transporter YP_001726851.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_4113 membrane channel protein component of Pn transporter YP_001726852.1 may be involved in phosphonate uptake and biodegradation YP_001726853.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: ssn:SSON_4277 phosphonate metabolism YP_001726854.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: sdy:SDY_4116 phosphonate metabolism YP_001726855.1 PFAM: phosphonate metabolism; KEGG: ssn:SSON_4275 phosphonate metabolism YP_001726856.1 PFAM: phosphonate metabolism PhnJ; KEGG: sbo:SBO_4124 PhnJ YP_001726857.1 KEGG: ssn:SSON_4273 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_001726858.1 KEGG: sdy:SDY_4120 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_001726859.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ssn:SSON_4271 phosphonate metabolism YP_001726860.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: ssn:SSON_4270 ATP-binding component of phosphonate transport YP_001726861.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_001726862.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001726863.1 KEGG: sbo:SBO_4117 hypothetical protein YP_001726864.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001726865.1 involved in rpiB and als operon repression YP_001726866.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: cko:CKO_03785 hypothetical protein YP_001726867.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains YP_001726868.1 PFAM: inner-membrane translocator; KEGG: cko:CKO_03787 hypothetical protein YP_001726869.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: cko:CKO_03788 hypothetical protein YP_001726870.1 PFAM: ROK family protein; KEGG: cko:CKO_03789 hypothetical protein YP_001726871.1 PFAM: beta-lactamase domain protein; KEGG: ssn:SSON_4265 hypothetical protein YP_001726872.1 KEGG: sbo:SBO_4114 formate dehydrogenase H YP_001726873.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001726874.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001726875.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_001726876.1 Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: spt:SPA4103 formate dehydrogenase H YP_001726877.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: ssn:SSON_4259 hypothetical protein YP_001726878.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_001726879.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sfv:SFV_4135 part of formate-dependent nitrite reductase complex YP_001726880.1 TIGRFAM: cytochrome c nitrite reductase, accessory protein NrfF; PFAM: cytochrome C biogenesis protein; KEGG: sbo:SBO_4106 NrfG YP_001726881.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_001726882.1 TIGRFAM: cytochrome c nitrite reductase, NrfD subunit; PFAM: Polysulphide reductase NrfD; KEGG: ssn:SSON_4254 formate-dependent nitrate reductase complex transmembrane protein YP_001726883.1 TIGRFAM: cytochrome c nitrite reductase, Fe-S protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_4103 formate-dependent nitrite reductase complex Fe-S centers YP_001726884.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_001726885.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001726886.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001726887.1 PFAM: protein of unknown function DUF485; KEGG: sbo:SBO_4099 hypothetical protein YP_001726888.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001726889.1 PFAM: pentapeptide repeat protein; KEGG: sfx:S3593 hypothetical protein YP_001726890.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: sdy:SDY_4502 hypothetical protein YP_001726891.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sdy:SDY_4503 hypothetical protein YP_001726892.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sdy:SDY_4504 redox-sensing activator of SoxS YP_001726893.1 regulates genes involved in response to oxidative stress YP_001726894.1 PFAM: EAL domain protein; KEGG: sfv:SFV_4151 hypothetical protein YP_001726895.1 KEGG: sbo:SBO_4092 hypothetical protein YP_001726896.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_001726897.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001726898.1 PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_4510 hypothetical protein YP_001726899.1 PFAM: protein of unknown function UPF0047; KEGG: sdy:SDY_4511 hypothetical protein YP_001726900.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_001726901.1 KEGG: sbo:SBO_4083 hypothetical protein YP_001726902.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001726903.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001726904.1 unwinds double stranded DNA YP_001726905.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_4523 quinone oxidoreductase YP_001726906.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_001726907.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: ssn:SSON_4229 hypothetical protein YP_001726908.1 KEGG: sfv:SFV_4165 hypothetical protein YP_001726909.1 KEGG: sfl:SF4158 hypothetical protein YP_001726910.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_001726911.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_001726912.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sfv:SFV_4169 DNA-damage-inducible protein F YP_001726913.1 Represses a number of genes involved in the response to DNA damage YP_001726914.1 PFAM: diacylglycerol kinase; KEGG: sdy:SDY_4532 diacylglycerol kinase YP_001726915.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001726916.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001726917.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001726918.1 PFAM: Maltose operon periplasmic; KEGG: ssn:SSON_4215 periplasmic protein of mal regulon YP_001726919.1 porin involved in the transport of maltose and maltodextrins YP_001726920.1 with malEFG is involved in import of maltose/maltodextrin YP_001726921.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001726922.1 with MalKGE is involved in maltose transport into the cell YP_001726923.1 with MalKFE is involved in the transport of maltose into the cell YP_001726924.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter YP_001726925.1 PFAM: phosphate-starvation-inducible E; KEGG: sdy:SDY_4218 hypothetical protein YP_001726927.1 PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: sbo:SBO_4057 hypothetical protein YP_001726928.1 PFAM: protein of unknown function DUF1017; KEGG: sdy:SDY_4220 hypothetical protein YP_001726929.1 KEGG: ssn:SSON_4205 hypothetical protein YP_001726930.1 KEGG: sdy:SDY_4222 hypothetical protein YP_001726931.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001726932.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001726933.1 KEGG: sdy:SDY_4309 hypothetical protein YP_001726934.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001726935.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001726936.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; KEGG: ssn:SSON_4191 putative alpha helix protein YP_001726937.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001726938.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_001726939.1 PFAM: ShET2 enterotoxin domain protein; KEGG: yps:YPTB3305 enterotoxin-like protein YP_001726940.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001726941.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sdy:SDY_4328 isocitrate lyase YP_001726942.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001726943.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001726944.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_4083 hypothetical protein YP_001726945.1 involved in de novo purine biosynthesis YP_001726946.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001726947.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_001726948.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfx:S3660 sensor kinase for HydG, hydrogenase 3 activity YP_001726949.1 KEGG: sdy:SDY_3724 hypothetical protein YP_001726950.1 PFAM: protein of unknown function DUF1481; KEGG: sdy:SDY_3725 hypothetical protein YP_001726951.1 histone-like DNA-binding protein YP_001726952.1 PFAM: protein of unknown function DUF416; KEGG: ssn:SSON_4172 hypothetical protein YP_001726953.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001726954.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001726955.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001726956.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001726957.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001726958.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001726959.1 TIGRFAM: thiazole biosynthesis adenylyltransferase ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sfv:SFV_4064 thiamin biosynthesis, thiazole moiety YP_001726960.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001726961.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001726962.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001726963.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001726964.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001726965.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001726966.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001726967.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001726968.1 binds directly to 23S ribosomal RNA YP_001726969.1 Modulates Rho-dependent transcription termination YP_001726970.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001726971.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001726972.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001726973.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001726974.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001726975.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001726976.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_001726977.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001726978.1 PFAM: protein of unknown function DUF1422; KEGG: sbo:SBO_3983 hypothetical protein YP_001726979.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001726980.1 catalyzes the conversion of NADPH to NADH YP_001726981.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001726982.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001726983.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001726984.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001726985.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001726986.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001726987.1 PFAM: sulfatase; KEGG: sbo:SBO_3974 hypothetical protein YP_001726988.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_3973 putative AraC-type regulatory protein YP_001726989.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_001726990.1 KEGG: sdy:SDY_3787 probable pyruvate formate lyase activating enzyme 2; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein YP_001726991.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_001726992.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_001726993.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_001726994.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: cko:CKO_03046 hypothetical protein YP_001726995.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001726996.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001726997.1 PFAM: protein of unknown function DUF1287; KEGG: sbo:SBO_3964 hypothetical protein YP_001726998.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4117 hypothetical protein YP_001726999.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: sfv:SFV_4012 catalase; hydroperoxidase HPI(I) YP_001727000.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001727001.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001727002.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001727003.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001727004.1 member of the NlpC/P60 superfamily of peptidases YP_001727005.1 PFAM: Insertion element protein; KEGG: sdy:SDY_P028 iso-IS1 ORF1 YP_001727006.1 TIGRFAM: YD repeat protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_001727007.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001727008.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001727009.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001727010.1 TIGRFAM: cell division protein FtsN; PFAM: Sporulation domain protein; KEGG: sbo:SBO_3950 essential cell division protein YP_001727011.1 heat shock protein involved in degradation of misfolded proteins YP_001727012.1 heat shock protein involved in degradation of misfolded proteins YP_001727013.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001727014.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001727015.1 PFAM: protein of unknown function DUF904; KEGG: sdy:SDY_3816 hypothetical protein YP_001727016.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: ssn:SSON_4096 facilitated diffusion of glycerol YP_001727017.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001727018.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001727019.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sdy:SDY_3820 ferredoxin-NADP reductase YP_001727020.1 with UspC and Usp E is involved in resistance to UV radiation YP_001727021.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_4091 hypothetical protein YP_001727022.1 PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_4090 hypothetical protein YP_001727023.1 PFAM: protein of unknown function DUF1454; KEGG: sbo:SBO_3937 hypothetical protein YP_001727024.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001727025.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: sbo:SBO_3935 CDP-diacylglycerol phosphotidylhydrolase YP_001727026.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_4086 periplasmic sulfate-binding protein YP_001727027.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001727028.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001727029.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_001727030.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001727031.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001727032.1 PFAM: 3-alpha domain protein; MOSC domain containing protein; KEGG: sbo:SBO_3928 hypothetical protein YP_001727033.1 transports degraded pectin products into the bacterial cell YP_001727034.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_001727035.1 transports L-rhamnose and L-lyxose into the cell YP_001727036.1 activates the expression of rhaRS in response to L-rhamnose YP_001727037.1 activates the expression of the rhaBAD operon and rhaT gene YP_001727038.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_001727039.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_001727040.1 KEGG: ssn:SSON_4072 rhamnulose-phosphate aldolase; TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein YP_001727041.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: sfv:SFV_3594 hypothetical protein YP_001727042.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system YP_001727043.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS fructose-specific IIB subunit; KEGG: sbo:SBO_3915 PTS system fructose-like enzyme IIBC component YP_001727044.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars YP_001727045.1 putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system YP_001727046.1 KEGG: sbo:SBO_3910 hypothetical protein YP_001727047.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001727048.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sbo:SBO_3908 formate dehydrogenase-O, major subunit; KEGG: ssn:SSON_4063 formate dehydrogenase-O, major subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molydopterin dinucleotide-binding region YP_001727049.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbo:SBO_3907 formate dehydrogenase-O, iron-sulfur subunit YP_001727050.1 cytochrome b556(FDO) component; heme containing YP_001727051.1 required for the formation of active formate dehydrogenase YP_001727052.1 KEGG: sbo:SBO_3904 hypothetical protein YP_001727053.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sfv:SFV_3606 hypothetical protein YP_001727054.1 TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; Thioesterase putative; KEGG: sbo:SBO_3902 putative acetyltransferase YP_001727055.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001727056.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001727057.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ssn:SSON_4054 putative phosphatase YP_001727058.1 PFAM: Aldose 1-epimerase; KEGG: sbo:SBO_3898 hypothetical protein YP_001727059.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4052 putative transport protein shikimate YP_001727060.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4051 putative transporter YP_001727061.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_4050 putative dehydrogenase YP_001727062.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ssn:SSON_4049 putative aldolase YP_001727063.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ssn:SSON_4048 putative dehydrogenase YP_001727064.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_3886 putative kinase YP_001727065.1 PFAM: regulatory protein GntR HTH; regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: ssn:SSON_4045 putative DeoR-type transcriptional regulator YP_001727066.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3626 putative resistance protein (transport) YP_001727067.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sfx:S3803 hypothetical protein YP_001727068.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sfv:SFV_3628 putative transcriptional regulator YP_001727069.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: sdy:SDY_3872 putative GTP-binding factor YP_001727070.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001727071.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001727072.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001727073.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001727074.1 PFAM: protein of unknown function DUF414; KEGG: sdy:SDY_3877 hypothetical protein YP_001727075.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001727076.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001727077.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: ssn:SSON_4035 putative endonuclease YP_001727078.1 PFAM: protein of unknown function DUF945; KEGG: sfx:S3815 putative GTP-binding protein YP_001727079.1 PFAM: DSBA oxidoreductase; KEGG: sbo:SBO_3872 protein disulfide isomerase I YP_001727080.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001727081.1 PFAM: protein of unknown function DUF1040; KEGG: sdy:SDY_3887 hypothetical protein YP_001727082.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001727083.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_001727084.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_001727085.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: sdy:SDY_3896 potassium uptake protein YP_001727086.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: sdy:SDY_3897 hypothetical protein YP_001727087.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001727088.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001727089.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001727090.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001727091.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001727092.1 TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; KEGG: sdy:SDY_3903 transcriptional activator affecting biosynthesis of lipopolysaccharide core, F pilin, and haemolysin YP_001727093.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001727094.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001727095.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001727096.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001727097.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001727098.1 PFAM: Sterol-binding domain protein; KEGG: sbo:SBO_3848 hypothetical protein YP_001727099.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001727100.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_001727101.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001727102.1 PFAM: dienelactone hydrolase; KEGG: sfl:SF3908 carboxymethylenebutenolidase YP_001727103.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001727104.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3840 MetR YP_001727105.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4001 hypothetical protein YP_001727106.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001727107.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001727108.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3674 hypothetical protein YP_001727109.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3675 hypothetical protein YP_001727110.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001727111.1 catalyzes the hydrolysis of phosphatidylcholine YP_001727112.1 PFAM: thioesterase superfamily protein; KEGG: ssn:SSON_3994 hypothetical protein YP_001727113.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfv:SFV_3679 hypothetical protein YP_001727114.1 KEGG: sfx:S3859 hypothetical protein YP_001727115.1 KEGG: sfv:SFV_3681 hypothetical protein YP_001727116.1 responsible for the influx of magnesium ions YP_001727117.1 KEGG: sdy:SDY_3930 predicted periplasmic protein YP_001727118.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001727119.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_001727120.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001727121.1 PFAM: protein of unknown function DUF484; KEGG: sbo:SBO_3821 hypothetical protein YP_001727122.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001727123.1 KEGG: ssn:SSON_3981 hypothetical protein YP_001727124.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001727125.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001727126.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001727127.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_001727128.1 PFAM: protein of unknown function DUF513 hemX; KEGG: sfx:S3881 uroporphyrinogen III methylase YP_001727129.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: sbo:SBO_3813 HemY YP_001727130.1 PFAM: Radical SAM domain protein; KEGG: sfv:SFV_3703 putative arylsulfatase regulator YP_001727131.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_001727132.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: sdy:SDY_3953 probable UDP-N-acetyl-D-mannosaminuronic acid transferase YP_001727133.1 enterobacterial common antigen polymerase YP_001727134.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001727135.1 PFAM: polysaccharide biosynthesis protein; KEGG: sbo:SBO_3803 putative cytochrome YP_001727136.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001727137.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_3714 hypothetical protein YP_001727138.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfv:SFV_3715 glucose-1-phosphate thymidylyltransferase YP_001727139.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ssn:SSON_3960 dTDP-glucose 4,6-dehydratase YP_001727140.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001727141.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: sdy:SDY_3962 UDP-N-acetyl glucosamine -2-epimerase YP_001727142.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001727143.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: ssn:SSON_3956 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase YP_001727144.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001727145.1 KEGG: sdy:SDY_3967 rho operon leader peptide YP_001727146.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cko:CKO_00123 hypothetical protein YP_001727147.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001727148.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001727149.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001727150.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cko:CKO_00116 hypothetical protein YP_001727151.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001727152.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001727153.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001727154.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001727155.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001727156.1 KEGG: sdy:SDY_3979 acetolactate synthase II, valine insensitive, small subunit YP_001727157.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001727158.1 PFAM: IlvGEDA operon leader peptide; KEGG: sdy:SDY_3981 ilvGMEDA operon leader peptide YP_001727159.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function YP_001727160.1 PFAM: protein of unknown function DUF413; KEGG: sdy:SDY_3984 hypothetical protein YP_001727161.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001727162.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfv:SFV_3744 hypothetical protein YP_001727163.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_3993 putative transport protein YP_001727164.1 DNA-binding transcriptional repressor of ribose metabolism YP_001727165.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001727166.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001727167.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001727168.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001727169.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001727170.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001727171.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001727172.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001727173.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001727174.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001727175.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001727176.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001727177.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001727178.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001727179.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001727180.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001727181.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001727182.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001727183.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001727184.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001727185.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001727186.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001727187.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001727188.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001727189.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_3654 high-affinity phosphate-specific transport system periplasmic phosphate-binding protein YP_001727190.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001727191.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001727192.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001727193.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001727194.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator YP_001727195.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001727196.1 PFAM: glycoside hydrolase family 1; KEGG: sfv:SFV_3786 phospho-beta-glucosidase B; cryptic YP_001727197.1 PFAM: porin LamB type; KEGG: ssn:SSON_3915 putative receptor protein YP_001727198.1 PFAM: putative esterase; glycoside hydrolase family 13 domain protein; KEGG: sfx:S4034 putative xylanase YP_001727199.1 PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfv:SFV_3789 putative isomerase YP_001727200.1 PFAM: protein of unknown function UPF0167; KEGG: sfv:SFV_3790 hypothetical protein YP_001727201.1 might be involved in hypersensitivity to nitrofurzone YP_001727202.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_001727203.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: sdy:SDY_4199 putative membrane/transport protein YP_001727204.1 PFAM: NADPH-dependent FMN reductase; KEGG: sfv:SFV_3798 hypothetical protein YP_001727205.1 KEGG: sbo:SBO_3663 hypothetical protein YP_001727206.1 Involved in anaerobic NO protection YP_001727207.1 Confers resistance to chloramphenicol YP_001727208.1 tryptophan transporter of low affinity YP_001727209.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_001727210.1 TIGRFAM: tryptophanase leader peptide; PFAM: tryptophanese operon leader peptide; KEGG: sfx:S4016 tryptophanase leader peptide YP_001727211.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001727212.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001727213.1 PFAM: protein of unknown function DUF37; KEGG: sdy:SDY_4187 hypothetical protein YP_001727214.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001727215.1 in Escherichia coli transcription of this gene is enhanced by polyamines