-- dump date 20140619_081330 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 481805000001 SEQ_END SEQ_END NC_010468.1 4746218 4746218 DR NC_010468.1; contig end 4746218..4746218 Escherichia coli ATCC 8739 YP_001723016.1 CDS dnaA NC_010468.1 48 1451 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 48..1451 Escherichia coli ATCC 8739 6064751 YP_001723017.1 CDS EcolC_0002 NC_010468.1 1456 2556 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1456..2556 Escherichia coli ATCC 8739 6068524 YP_001723018.1 CDS recF NC_010468.1 2556 3629 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2556..3629 Escherichia coli ATCC 8739 6068546 YP_001723019.1 CDS gyrB NC_010468.1 3658 6072 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 3658..6072 Escherichia coli ATCC 8739 6068732 YP_001723020.1 CDS EcolC_0005 NC_010468.1 6312 6710 D PFAM: protein of unknown function DUF937; KEGG: ssn:SSON_3648 hypothetical protein; hypothetical protein 6312..6710 Escherichia coli ATCC 8739 6064907 YP_001723021.1 CDS EcolC_0006 NC_010468.1 6825 7637 D YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 6825..7637 Escherichia coli ATCC 8739 6068520 YP_001723022.1 CDS EcolC_0007 NC_010468.1 7683 8339 R KEGG: sfl:SF3768 putative replicase; hypothetical protein complement(7683..8339) Escherichia coli ATCC 8739 6068556 YP_001723023.1 CDS EcolC_0008 NC_010468.1 8617 9306 D PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfx:S4002 regulator protein for dgo operon; GntR family transcriptional regulator 8617..9306 Escherichia coli ATCC 8739 6064792 YP_001723024.1 CDS EcolC_0009 NC_010468.1 9303 10181 D PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: ssn:SSON_3644 2-oxo-3-deoxygalactonate kinase; 2-dehydro-3-deoxygalactonokinase 9303..10181 Escherichia coli ATCC 8739 6064694 YP_001723025.1 CDS EcolC_0010 NC_010468.1 10165 10782 D catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 10165..10782 Escherichia coli ATCC 8739 6066883 YP_001723026.1 CDS EcolC_0011 NC_010468.1 10779 11927 D PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ent:Ent638_0009 mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; galactonate dehydratase 10779..11927 Escherichia coli ATCC 8739 6068511 YP_001723027.1 CDS EcolC_0012 NC_010468.1 12047 13339 D TIGRFAM: phosphoglycerate transporter; d-galactonate transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3642 D-galactonate transport; d-galactonate transporter 12047..13339 Escherichia coli ATCC 8739 6068536 YP_001723028.1 CDS EcolC_0013 NC_010468.1 13336 14400 R FAD/NAD(P)-binding domain; putative oxidoreductase complement(13336..14400) Escherichia coli ATCC 8739 6068510 YP_001723029.1 CDS EcolC_0014 NC_010468.1 14501 15715 D KEGG: ssn:SSON_3640 hypothetical protein; hypothetical protein 14501..15715 Escherichia coli ATCC 8739 6065084 YP_001723030.1 CDS EcolC_0015 NC_010468.1 15717 16124 R PFAM: protein of unknown function DUF1375; KEGG: sfv:SFV_3823 hypothetical protein; hypothetical protein complement(15717..16124) Escherichia coli ATCC 8739 6068494 YP_001723031.1 CDS EcolC_0016 NC_010468.1 16355 16768 D with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 16355..16768 Escherichia coli ATCC 8739 6068508 YP_001723032.1 CDS EcolC_0017 NC_010468.1 16880 17308 D 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 16880..17308 Escherichia coli ATCC 8739 6068504 YP_001723033.1 CDS EcolC_0018 NC_010468.1 17504 19165 D TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: sfx:S3992 putative transport protein; hypothetical protein 17504..19165 Escherichia coli ATCC 8739 6068509 YP_001723034.1 CDS EcolC_0019 NC_010468.1 19162 19878 R PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sdy:SDY_4170 putative transcriptional regulator; GntR family transcriptional regulator complement(19162..19878) Escherichia coli ATCC 8739 6068544 YP_001723035.1 CDS EcolC_0020 NC_010468.1 20174 21790 D TIGRFAM: PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, alpha-glucoside-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: ssn:SSON_3634 phosphotransferase system enzyme IIBC component; PTS system alpha-glucoside-specific transporter subunit IIBC 20174..21790 Escherichia coli ATCC 8739 6066592 YP_001723036.1 CDS EcolC_0021 NC_010468.1 21790 23112 D PFAM: glycoside hydrolase family 4; KEGG: sdy:SDY_4168 putative 6-phospho-beta-glucosidase; glycoside hydrolase family protein 21790..23112 Escherichia coli ATCC 8739 6068488 YP_001723037.1 CDS EcolC_0023 NC_010468.1 23681 24889 D KEGG: sdy:SDY_2598 putative virulence protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; IS605 family transposase OrfB 23681..24889 Escherichia coli ATCC 8739 6068477 YP_001723038.1 CDS EcolC_0024 NC_010468.1 25060 25407 D PFAM: protein of unknown function DUF202; KEGG: sdy:SDY_4160 hypothetical protein; isocitrate dehydrogenase 25060..25407 Escherichia coli ATCC 8739 6068484 YP_001723039.1 CDS EcolC_0025 NC_010468.1 25397 25759 D KEGG: sbo:SBO_3694 hypothetical protein; hypothetical protein 25397..25759 Escherichia coli ATCC 8739 6068486 YP_001723040.1 CDS EcolC_0026 NC_010468.1 25756 26253 D KEGG: sfv:SFV_3836 putative transcriptional regulator; putative transcriptional regulator 25756..26253 Escherichia coli ATCC 8739 6068487 YP_001723041.1 CDS emrD NC_010468.1 26261 27445 R multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D complement(26261..27445) Escherichia coli ATCC 8739 6068658 YP_001723042.1 CDS EcolC_0028 NC_010468.1 28583 30271 D TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sfx:S3978 acetolactate synthase I, valine-sensitive, large subunit; acetolactate synthase catalytic subunit 28583..30271 Escherichia coli ATCC 8739 6068661 YP_001723043.1 CDS EcolC_0029 NC_010468.1 30275 30565 D with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 30275..30565 Escherichia coli ATCC 8739 6068513 YP_001723044.1 CDS EcolC_0030 NC_010468.1 30640 31230 D response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 30640..31230 Escherichia coli ATCC 8739 6068475 YP_001723045.1 CDS EcolC_0031 NC_010468.1 31230 32732 D Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 31230..32732 Escherichia coli ATCC 8739 6068480 YP_001723046.1 CDS EcolC_0032 NC_010468.1 32742 34061 D membrane protein regulates uhpT expression; regulatory protein UhpC 32742..34061 Escherichia coli ATCC 8739 6068496 YP_001723047.1 CDS uhpT NC_010468.1 34199 35590 D cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 34199..35590 Escherichia coli ATCC 8739 6068519 YP_001723048.1 CDS EcolC_0034 NC_010468.1 35635 37401 R catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase complement(35635..37401) Escherichia coli ATCC 8739 6068468 YP_001723049.1 CDS EcolC_0035 NC_010468.1 37576 38910 D PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfx:S3971 hypothetical protein; xanthine/uracil/vitamin C permease 37576..38910 Escherichia coli ATCC 8739 6068479 YP_001723050.1 CDS EcolC_0036 NC_010468.1 38963 39415 D PFAM: protein of unknown function DUF1198; KEGG: sdy:SDY_4144 hypothetical protein; hypothetical protein 38963..39415 Escherichia coli ATCC 8739 6068467 YP_001723051.1 CDS nepI NC_010468.1 39461 40816 D experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 39461..40816 Escherichia coli ATCC 8739 6068507 YP_001723052.1 CDS EcolC_0038 NC_010468.1 40857 41150 R KEGG: sbo:SBO_3710 putative transport protein; putative transport protein complement(40857..41150) Escherichia coli ATCC 8739 6067597 YP_001723053.1 CDS EcolC_0039 NC_010468.1 41372 42190 D TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sdy:SDY_4499 lipoprotein-28; hypothetical protein 41372..42190 Escherichia coli ATCC 8739 6066370 YP_001723054.1 CDS EcolC_0040 NC_010468.1 42194 43117 R TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sdy:SDY_4498 putative permease transporter; carboxylate/amino acid/amine transporter complement(42194..43117) Escherichia coli ATCC 8739 6068448 YP_001723055.1 CDS EcolC_0041 NC_010468.1 43228 44412 R TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_0909 putative transport; sugar efflux transporter complement(43228..44412) Escherichia coli ATCC 8739 6068462 YP_001723056.1 CDS EcolC_0043 NC_010468.1 45542 47875 R KEGG: stt:t2656 hypothetical protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 protein; TOPRIM domain protein; P4 alpha zinc-binding domain protein; primase P4; SMART: Toprim sub domain protein; P4 family phage/plasmid primase complement(45542..47875) Escherichia coli ATCC 8739 6068457 YP_001723057.1 CDS EcolC_0044 NC_010468.1 47890 48210 R KEGG: sbo:SBO_4166 putative protein encoded in prophage; putative prophage protein complement(47890..48210) Escherichia coli ATCC 8739 6068464 YP_001723058.1 CDS EcolC_0045 NC_010468.1 48346 48801 R KEGG: stt:t2654 hypothetical protein; hypothetical protein complement(48346..48801) Escherichia coli ATCC 8739 6065092 YP_001723059.1 CDS EcolC_0046 NC_010468.1 48794 49081 R KEGG: stt:t2653 hypothetical protein; hypothetical protein complement(48794..49081) Escherichia coli ATCC 8739 6068452 YP_001723060.1 CDS EcolC_0047 NC_010468.1 49074 49664 R KEGG: sbo:SBO_4168 putative bacteriophage protein; putative bacteriophage protein complement(49074..49664) Escherichia coli ATCC 8739 6068431 YP_001723061.1 CDS EcolC_0048 NC_010468.1 49661 49927 R PFAM: Prophage CP4-57 regulatory; KEGG: sbo:SBO_4169 hypothetical protein; phage transcriptional regulator, AlpA complement(49661..49927) Escherichia coli ATCC 8739 6068440 YP_001723062.1 CDS EcolC_0049 NC_010468.1 50480 51214 D KEGG: sbo:SBO_4170 hypothetical protein; hypothetical protein 50480..51214 Escherichia coli ATCC 8739 6068649 YP_001723063.1 CDS EcolC_0050 NC_010468.1 51214 51456 D PFAM: transcriptional activator Ogr/delta; KEGG: spt:SPA4293 hypothetical protein; transcriptional activator Ogr/delta 51214..51456 Escherichia coli ATCC 8739 6065350 YP_001723064.1 CDS EcolC_0051 NC_010468.1 51480 52043 D PFAM: polarity suppression protein; KEGG: stt:t2648 hypothetical protein; polarity suppression protein 51480..52043 Escherichia coli ATCC 8739 6068470 YP_001723065.1 CDS EcolC_0052 NC_010468.1 52323 54089 R KEGG: sfr:Sfri_0781 kap P-loop domain protein; hypothetical protein complement(52323..54089) Escherichia coli ATCC 8739 6068439 YP_001723066.1 CDS EcolC_0053 NC_010468.1 54119 55294 R PFAM: integrase family protein; KEGG: spe:Spro_0108 integrase family protein; integrase family protein complement(54119..55294) Escherichia coli ATCC 8739 6068469 YP_001723067.1 CDS EcolC_0054 NC_010468.1 55844 57226 D may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter 55844..57226 Escherichia coli ATCC 8739 6068449 YP_001723068.1 CDS EcolC_0055 NC_010468.1 57236 59554 D catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 57236..59554 Escherichia coli ATCC 8739 6068428 YP_001723069.1 CDS EcolC_0056 NC_010468.1 59607 61316 R PFAM: AsmA family protein; KEGG: sfx:S4074 hypothetical protein; AsmA family protein complement(59607..61316) Escherichia coli ATCC 8739 6068445 YP_001723070.1 CDS EcolC_0057 NC_010468.1 61437 62828 R TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3751 putative transport protein; uracil-xanthine permease complement(61437..62828) Escherichia coli ATCC 8739 6068444 YP_001723071.1 CDS EcolC_0058 NC_010468.1 63108 64313 D PFAM: sodium/glutamate symporter; KEGG: sdy:SDY_4085 glutamate transport; sodium/glutamate symporter 63108..64313 Escherichia coli ATCC 8739 6065414 YP_001723072.1 CDS EcolC_0059 NC_010468.1 64482 66563 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(64482..66563) Escherichia coli ATCC 8739 6065282 YP_001723073.1 CDS EcolC_0060 NC_010468.1 66569 67258 R specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase complement(66569..67258) Escherichia coli ATCC 8739 6068411 YP_001723074.1 CDS EcolC_0061 NC_010468.1 67265 69373 R KEGG: sbo:SBO_3727 (p)ppGpp synthetase II; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase complement(67265..69373) Escherichia coli ATCC 8739 6068417 YP_001723075.1 CDS rpoZ NC_010468.1 69392 69667 R promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(69392..69667) Escherichia coli ATCC 8739 6068418 YP_001723076.1 CDS gmk NC_010468.1 69722 70345 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(69722..70345) Escherichia coli ATCC 8739 6066673 YP_001723077.1 CDS ligB NC_010468.1 70603 72285 D this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 70603..72285 Escherichia coli ATCC 8739 6068395 YP_001723078.1 CDS EcolC_0065 NC_010468.1 72282 72899 R PFAM: protein of unknown function UPF0126; KEGG: sdy:SDY_4077 hypothetical protein; hypothetical protein complement(72282..72899) Escherichia coli ATCC 8739 6068427 YP_001723079.1 CDS dinD NC_010468.1 73190 74014 R KEGG: sbo:SBO_3734 DNA-damage-inducible protein; DNA-damage-inducible protein D complement(73190..74014) Escherichia coli ATCC 8739 6068397 YP_001723080.1 CDS EcolC_0067 NC_010468.1 74235 75098 R PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ssn:SSON_3762 putative alpha helix protein; hypothetical protein complement(74235..75098) Escherichia coli ATCC 8739 6068414 YP_001723081.1 CDS rph NC_010468.1 75225 75941 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 75225..75941 Escherichia coli ATCC 8739 6068420 YP_001723082.1 CDS pyrE NC_010468.1 76007 76648 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 76007..76648 Escherichia coli ATCC 8739 6068388 YP_001723083.1 CDS slmA NC_010468.1 76685 77281 R FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein complement(76685..77281) Escherichia coli ATCC 8739 6068408 YP_001723084.1 CDS dut NC_010468.1 77388 77846 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(77388..77846) Escherichia coli ATCC 8739 6068390 YP_001723085.1 CDS EcolC_0072 NC_010468.1 77824 79044 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(77824..79044) Escherichia coli ATCC 8739 6068386 YP_001723086.1 CDS radC NC_010468.1 79240 79884 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 79240..79884 Escherichia coli ATCC 8739 6068394 YP_001723087.1 CDS rpmB NC_010468.1 80101 80337 D required for 70S ribosome assembly; 50S ribosomal protein L28 80101..80337 Escherichia coli ATCC 8739 6068399 YP_001723088.1 CDS rpmG NC_010468.1 80358 80525 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 80358..80525 Escherichia coli ATCC 8739 6068407 YP_001723089.1 CDS EcolC_0076 NC_010468.1 80623 81432 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 80623..81432 Escherichia coli ATCC 8739 6068403 YP_001723090.1 CDS coaD NC_010468.1 81471 81950 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(81471..81950) Escherichia coli ATCC 8739 6068404 YP_001723091.1 CDS EcolC_0078 NC_010468.1 81958 83235 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(81958..83235) Escherichia coli ATCC 8739 6068381 YP_001723092.1 CDS EcolC_0079 NC_010468.1 83684 84706 D TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: sdy:SDY_4062 lipopolysaccharide core biosynthesis protein; lipopolysaccharide core biosynthesis protein 83684..84706 Escherichia coli ATCC 8739 6068372 YP_001723093.1 CDS EcolC_0080 NC_010468.1 84703 85827 D PFAM: glycosyl transferase group 1; KEGG: sdy:SDY_4061 glucosyltransferase I; group 1 glycosyl transferase 84703..85827 Escherichia coli ATCC 8739 6068377 YP_001723094.1 CDS EcolC_0081 NC_010468.1 85820 86617 D PFAM: lipopolysaccharide kinase; KEGG: sdy:SDY_4060 putative LPS biosynthesis enzyme; lipopolysaccharide kinase 85820..86617 Escherichia coli ATCC 8739 6068392 YP_001723095.1 CDS EcolC_0082 NC_010468.1 86633 87649 D PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3631 UDP-D-galactose:(glucosyl)lipopolysaccharide-alpha-1, 3-D-galactosylt ransferase; lipopolysaccharide 3-alpha-galactosyltransferase 86633..87649 Escherichia coli ATCC 8739 6068385 YP_001723096.1 CDS EcolC_0083 NC_010468.1 87666 88661 D PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3630 lipopolysaccharide 1,2-glucosyltransferase; lipopolysaccharide glucosyltransferase I 87666..88661 Escherichia coli ATCC 8739 6068355 YP_001723097.1 CDS EcolC_0084 NC_010468.1 88671 89363 D PFAM: lipopolysaccharide core biosynthesis protein; KEGG: sdy:SDY_4057 lipopolysaccharide core biosynthesis protein RfaY; lipopolysaccharide core biosynthesis protein 88671..89363 Escherichia coli ATCC 8739 6068379 YP_001723098.1 CDS EcolC_0085 NC_010468.1 89389 90414 D PFAM: glycosyl transferase family 8; Glycosyl transferase family 8 domain protein; KEGG: ssn:SSON_3781 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase; lipopolysaccharide glucosyltransferase I 89389..90414 Escherichia coli ATCC 8739 6068369 YP_001723099.1 CDS EcolC_0086 NC_010468.1 90499 91482 D PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_3782 putative beta1,3-glucosyltransferase; glycosyl transferase family protein 90499..91482 Escherichia coli ATCC 8739 6068410 YP_001723100.1 CDS EcolC_0087 NC_010468.1 91528 92781 D PFAM: O-antigen polymerase; KEGG: ssn:SSON_3783 lipid A-core, surface polymer ligase; O-antigen polymerase 91528..92781 Escherichia coli ATCC 8739 6068621 YP_001723101.1 CDS EcolC_0088 NC_010468.1 92851 93822 R TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: ssn:SSON_3784 heptosyl transferase I; ADP-heptose--LPS heptosyltransferase complement(92851..93822) Escherichia coli ATCC 8739 6068382 YP_001723102.1 CDS EcolC_0089 NC_010468.1 93826 94872 R catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase complement(93826..94872) Escherichia coli ATCC 8739 6068622 YP_001723103.1 CDS rfaD NC_010468.1 94882 95814 R catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase complement(94882..95814) Escherichia coli ATCC 8739 6068344 YP_001723104.1 CDS EcolC_0091 NC_010468.1 96028 97224 D catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 96028..97224 Escherichia coli ATCC 8739 6065061 YP_001723105.1 CDS tdh NC_010468.1 97234 98259 D converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 97234..98259 Escherichia coli ATCC 8739 6068362 YP_001723106.1 CDS EcolC_0093 NC_010468.1 98498 99532 D PFAM: glycosyl transferase family 2; KEGG: sdy:SDY_4048 putative regulator; putative glycosyl transferase 98498..99532 Escherichia coli ATCC 8739 6065136 YP_001723107.1 CDS EcolC_0094 NC_010468.1 99519 100478 R PFAM: protein of unknown function DUF610 YibQ; KEGG: sfx:S4115 hypothetical protein; hypothetical protein complement(99519..100478) Escherichia coli ATCC 8739 6068368 YP_001723108.2 CDS EcolC_0095 NC_010468.1 100482 101765 R PFAM: peptidase M23B; KEGG: ssn:SSON_3792 hypothetical protein; hypothetical protein complement(100482..101765) Escherichia coli ATCC 8739 6068358 YP_001723109.1 CDS EcolC_0096 NC_010468.1 101775 103319 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase complement(101775..103319) Escherichia coli ATCC 8739 6068354 YP_001723110.1 CDS EcolC_0097 NC_010468.1 103564 103995 D PFAM: Rhodanese domain protein; KEGG: sbo:SBO_3617 hypothetical protein; rhodanese domain-containing protein 103564..103995 Escherichia coli ATCC 8739 6068346 YP_001723111.1 CDS EcolC_0098 NC_010468.1 104137 104388 D TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; KEGG: sdy:SDY_4043 glutaredoxin 3; glutaredoxin 3 104137..104388 Escherichia coli ATCC 8739 6065709 YP_001723112.1 CDS EcolC_0099 NC_010468.1 104451 104918 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 104451..104918 Escherichia coli ATCC 8739 6068651 YP_001723113.1 CDS gpsA NC_010468.1 104918 105937 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 104918..105937 Escherichia coli ATCC 8739 6068343 YP_001723114.1 CDS cysE NC_010468.1 106017 106838 D catalyzes the O-acetylation of serine; serine acetyltransferase 106017..106838 Escherichia coli ATCC 8739 6066777 YP_001723115.1 CDS EcolC_0102 NC_010468.1 106891 107364 R member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK complement(106891..107364) Escherichia coli ATCC 8739 6066893 YP_001723116.1 CDS lldD NC_010468.1 107518 108708 R flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase complement(107518..108708) Escherichia coli ATCC 8739 6068616 YP_001723117.1 CDS EcolC_0104 NC_010468.1 108705 109481 R represses the lctPRD operon; DNA-binding transcriptional repressor LldR complement(108705..109481) Escherichia coli ATCC 8739 6065420 YP_001723118.1 CDS EcolC_0105 NC_010468.1 109481 111136 R TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sbo:SBO_3608 L-lactate permease; L-lactate permease complement(109481..111136) Escherichia coli ATCC 8739 6065920 YP_001723119.1 CDS EcolC_0108 NC_010468.1 116572 117255 R KEGG: sfv:SFV_3931 putative inner membrane lipoprotein; putative inner membrane lipoprotein complement(116572..117255) Escherichia coli ATCC 8739 6067387 YP_001723120.1 CDS EcolC_0109 NC_010468.1 117799 118161 R KEGG: sbo:SBO_3601 hypothetical protein; hypothetical protein complement(117799..118161) Escherichia coli ATCC 8739 6065399 YP_001723121.1 CDS EcolC_0110 NC_010468.1 118446 118655 D KEGG: sbo:SBO_3600 putative cytoplasmic protein; putative cytoplasmic protein 118446..118655 Escherichia coli ATCC 8739 6068588 YP_001723122.1 CDS mtlR NC_010468.1 118667 119254 R Acts as a repressor of the mtlAD operon; mannitol repressor protein complement(118667..119254) Escherichia coli ATCC 8739 6068589 YP_001723123.1 CDS EcolC_0112 NC_010468.1 119254 120402 R PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfv:SFV_3937 mannitol-1-phosphate dehydrogenase; mannitol-1-phosphate 5-dehydrogenase complement(119254..120402) Escherichia coli ATCC 8739 6068587 YP_001723124.1 CDS EcolC_0113 NC_010468.1 120632 122545 R TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ssn:SSON_3809 PTS system, mannitol-specific enzyme IIABC components; PTS system mannitol-specific transporter subunit IIC complement(120632..122545) Escherichia coli ATCC 8739 6068598 YP_001723125.1 CDS EcolC_0114 NC_010468.1 123082 123444 D KEGG: sbo:SBO_3596 hypothetical protein; hypothetical protein 123082..123444 Escherichia coli ATCC 8739 6066960 YP_001723126.1 CDS EcolC_0115 NC_010468.1 123447 124583 D PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_3595 hypothetical protein; secretion protein HlyD family protein 123447..124583 Escherichia coli ATCC 8739 6065097 YP_001723127.1 CDS EcolC_0116 NC_010468.1 125043 125480 R hypothetical protein complement(125043..125480) Escherichia coli ATCC 8739 6068558 YP_001723128.1 CDS EcolC_0117 NC_010468.1 126187 126648 R KEGG: sbo:SBO_3594 hypothetical protein; hypothetical protein complement(126187..126648) Escherichia coli ATCC 8739 6068563 YP_001723129.1 CDS EcolC_0118 NC_010468.1 126660 127598 R PFAM: RHS protein; KEGG: sbo:SBO_3593 RhsA; RHS protein complement(126660..127598) Escherichia coli ATCC 8739 6064646 YP_001723130.1 CDS EcolC_0119 NC_010468.1 127646 128488 R PFAM: PBS lyase HEAT domain protein repeat-containing protein; KEGG: amr:AM1_4076 hypothetical protein; hypothetical protein complement(127646..128488) Escherichia coli ATCC 8739 6068538 YP_001723131.1 CDS EcolC_0120 NC_010468.1 128509 132642 R TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(128509..132642) Escherichia coli ATCC 8739 6068552 YP_001723132.1 CDS EcolC_0121 NC_010468.1 132870 133478 D PFAM: Glutathione S-transferase domain; KEGG: ssn:SSON_3816 putative S-transferase; putative glutathione S-transferase 132870..133478 Escherichia coli ATCC 8739 6068582 YP_001723133.1 CDS EcolC_0122 NC_010468.1 133576 134967 D catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 133576..134967 Escherichia coli ATCC 8739 6068525 YP_001723134.1 CDS EcolC_0123 NC_010468.1 134964 136808 D TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: ssn:SSON_3818 selenocysteinyl-tRNA-specific translation factor; selenocysteinyl-tRNA-specific translation factor 134964..136808 Escherichia coli ATCC 8739 6068371 YP_001723135.1 CDS EcolC_0124 NC_010468.1 136998 138149 D PFAM: iron-containing alcohol dehydrogenase; KEGG: sbo:SBO_3589 putative oxidoreductase; putative alcohol dehydrogenase 136998..138149 Escherichia coli ATCC 8739 6068432 YP_001723136.1 CDS EcolC_0125 NC_010468.1 138314 139852 D PFAM: Aldehyde Dehydrogenase_; KEGG: sfv:SFV_3945 aldehyde dehydrogenase B; aldehyde dehydrogenase 138314..139852 Escherichia coli ATCC 8739 6068348 YP_001723137.1 CDS EcolC_0126 NC_010468.1 140397 140720 D KEGG: sfv:SFV_3947 hypothetical protein; hypothetical protein 140397..140720 Escherichia coli ATCC 8739 6068336 YP_001723138.1 CDS EcolC_0127 NC_010468.1 140726 141862 D PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_3948 hypothetical protein; secretion protein HlyD family protein 140726..141862 Escherichia coli ATCC 8739 6068337 YP_001723139.1 CDS EcolC_0128 NC_010468.1 141859 142833 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_0144 transcriptional regulator, LysR family; LysR family transcriptional regulator complement(141859..142833) Escherichia coli ATCC 8739 6068334 YP_001723140.1 CDS EcolC_0129 NC_010468.1 142957 143697 D PFAM: MltA-interacting MipA family protein; KEGG: sfv:SFV_3952 putative outer membrane protein; MltA-interacting MipA family protein 142957..143697 Escherichia coli ATCC 8739 6068340 YP_001723141.1 CDS sgbE NC_010468.1 144044 144739 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(144044..144739) Escherichia coli ATCC 8739 6068329 YP_001723142.1 CDS EcolC_0132 NC_010468.1 144733 145593 R L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase complement(144733..145593) Escherichia coli ATCC 8739 6068325 YP_001723143.1 CDS sgbH NC_010468.1 145586 146248 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase complement(145586..146248) Escherichia coli ATCC 8739 6068331 YP_001723144.1 CDS EcolC_0134 NC_010468.1 146245 147741 R PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3959 L-xylulose kinase, cryptic; carbohydrate kinase FGGY complement(146245..147741) Escherichia coli ATCC 8739 6068516 YP_001723145.1 CDS EcolC_0135 NC_010468.1 147745 148731 R TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sfv:SFV_3960 putative solute-binding transport protein; TRAP dicarboxylate transporter subunit DctP complement(147745..148731) Escherichia coli ATCC 8739 6068360 YP_001723146.1 CDS EcolC_0136 NC_010468.1 148744 150021 R TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sfv:SFV_3961 hypothetical protein; TRAP dicarboxylate transporter subunit DctM complement(148744..150021) Escherichia coli ATCC 8739 6068319 YP_001723147.1 CDS EcolC_0138 NC_010468.1 150616 151083 R PFAM: conserved hypothetical protein; KEGG: cko:CKO_05034 hypothetical protein; hypothetical protein complement(150616..151083) Escherichia coli ATCC 8739 6068310 YP_001723148.1 CDS EcolC_0139 NC_010468.1 151095 152093 R NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase complement(151095..152093) Escherichia coli ATCC 8739 6068314 YP_001723149.1 CDS EcolC_0140 NC_010468.1 152294 153142 D PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sbo:SBO_3582 putative regulator; IclR family transcriptional regulator 152294..153142 Escherichia coli ATCC 8739 6068323 YP_001723150.1 CDS EcolC_0141 NC_010468.1 153244 153717 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_3581 hypothetical protein; 4Fe-4S ferredoxin 153244..153717 Escherichia coli ATCC 8739 6066817 YP_001723151.1 CDS avtA NC_010468.1 153868 155121 R transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase complement(153868..155121) Escherichia coli ATCC 8739 6068302 YP_001723152.1 CDS malS NC_010468.1 155299 157329 R periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase complement(155299..157329) Escherichia coli ATCC 8739 6068305 YP_001723153.1 CDS EcolC_0144 NC_010468.1 157649 158473 D PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2; KEGG: sbo:SBO_3578 putative ATP-binding protein; hypothetical protein 157649..158473 Escherichia coli ATCC 8739 6068297 YP_001723154.1 CDS EcolC_0145 NC_010468.1 158669 159847 R PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_3577 putative regulator of xyl operon; AraC family transcriptional regulator complement(158669..159847) Escherichia coli ATCC 8739 6068299 YP_001723155.1 CDS EcolC_0146 NC_010468.1 159925 161106 R PFAM: inner-membrane translocator; KEGG: sbo:SBO_3576 putative xylose transport, membrane component; monosaccharide-transporting ATPase complement(159925..161106) Escherichia coli ATCC 8739 6068306 YP_001723156.1 CDS EcolC_0147 NC_010468.1 161084 162625 R with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit complement(161084..162625) Escherichia coli ATCC 8739 6068295 YP_001723157.1 CDS xylF NC_010468.1 162703 163695 R periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF complement(162703..163695) Escherichia coli ATCC 8739 6068293 YP_001723158.1 CDS EcolC_0149 NC_010468.1 164061 165383 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 164061..165383 Escherichia coli ATCC 8739 6068285 YP_001723159.1 CDS EcolC_0150 NC_010468.1 165455 166909 D TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3976 xylulokinase; xylulokinase 165455..166909 Escherichia coli ATCC 8739 6068286 YP_001723160.1 CDS EcolC_0151 NC_010468.1 167078 167419 D PFAM: YiaAB two helix domain protein; KEGG: sbo:SBO_3571 hypothetical protein; hypothetical protein 167078..167419 Escherichia coli ATCC 8739 6068278 YP_001723161.1 CDS EcolC_0152 NC_010468.1 167465 167902 D PFAM: YiaAB two helix domain protein; KEGG: sbo:SBO_3570 hypothetical protein; hypothetical protein 167465..167902 Escherichia coli ATCC 8739 6068279 YP_001723162.1 CDS EcolC_0153 NC_010468.1 167944 168939 R PFAM: acyltransferase 3; KEGG: sdy:SDY_4340 hypothetical protein; acyltransferase 3 complement(167944..168939) Escherichia coli ATCC 8739 6068274 YP_001723163.1 CDS EcolC_0154 NC_010468.1 169114 169413 D KEGG: sbo:SBO_3566 putative lipoprotein; putative lipoprotein 169114..169413 Escherichia coli ATCC 8739 6068270 YP_001723164.1 CDS glyQ NC_010468.1 169508 170419 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 169508..170419 Escherichia coli ATCC 8739 6068272 YP_001723165.1 CDS glyS NC_010468.1 170429 172498 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 170429..172498 Escherichia coli ATCC 8739 6068269 YP_001723166.1 CDS EcolC_0157 NC_010468.1 172786 173589 R PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family; integrase catalytic subunit complement(172786..173589) Escherichia coli ATCC 8739 6068273 YP_001723167.1 CDS EcolC_0158 NC_010468.1 173637 173921 R PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein complement(173637..173921) Escherichia coli ATCC 8739 6068266 YP_001723168.1 CDS EcolC_0159 NC_010468.1 174054 174206 D PFAM: Hok/gef cell toxic protein; KEGG: ssn:SSON_3831 putative membrane permeability altering protein; small toxic polypeptide 174054..174206 Escherichia coli ATCC 8739 6068268 YP_001723169.1 CDS EcolC_0160 NC_010468.1 174393 174605 R PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: cko:CKO_05012 hypothetical protein; major cold shock protein complement(174393..174605) Escherichia coli ATCC 8739 6068264 YP_001723170.1 CDS EcolC_0161 NC_010468.1 174886 175176 R SMART: helix-turn-helix domain protein; KEGG: sdy:SDY_4348 hypothetical protein; putative transcriptional regulator complement(174886..175176) Escherichia coli ATCC 8739 6064715 YP_001723171.1 CDS EcolC_0162 NC_010468.1 175610 176320 D KEGG: sdy:SDY_4349 hypothetical protein; hypothetical protein 175610..176320 Escherichia coli ATCC 8739 6068257 YP_001723172.1 CDS EcolC_0163 NC_010468.1 176370 177344 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sbo:SBO_3555 putative dehydrogenase; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase complement(176370..177344) Escherichia coli ATCC 8739 6068261 YP_001723173.1 CDS EcolC_0164 NC_010468.1 177448 178107 R PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: ssn:SSON_3836 putative outer membrane protein; putative outer membrane lipoprotein complement(177448..178107) Escherichia coli ATCC 8739 6068253 YP_001723174.1 CDS EcolC_0165 NC_010468.1 178260 180593 D TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_3536 biotin sulfoxide reductase; molybdopterin guanine dinucleotide-containing S/N-oxide reductase 178260..180593 Escherichia coli ATCC 8739 6068262 YP_001723175.1 CDS EcolC_0166 NC_010468.1 180562 181002 R PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_3840 hypothetical protein; hypothetical protein complement(180562..181002) Escherichia coli ATCC 8739 6068288 YP_001723176.1 CDS EcolC_0167 NC_010468.1 180999 181562 R constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase complement(180999..181562) Escherichia coli ATCC 8739 6068283 YP_001723177.1 CDS EcolC_0168 NC_010468.1 181720 182418 D KEGG: sbo:SBO_3550 putative lipase; putative lipase 181720..182418 Escherichia coli ATCC 8739 6068281 YP_001723178.1 CDS EcolC_0169 NC_010468.1 182647 183855 D TIGRFAM: Oxalate/Formate Antiporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_3843 putative resistance protein; oxalate/formate antiporter 182647..183855 Escherichia coli ATCC 8739 6068276 YP_001723179.1 CDS EcolC_0170 NC_010468.1 184179 185870 D catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 184179..185870 Escherichia coli ATCC 8739 6068246 YP_001723180.1 CDS EcolC_0171 NC_010468.1 186949 188556 D PFAM: extracellular solute-binding protein family 5; KEGG: sdy:SDY_4567 dipeptide transport protein; 4-phytase 186949..188556 Escherichia coli ATCC 8739 6068251 YP_001723181.1 CDS EcolC_0172 NC_010468.1 188864 189883 D transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 188864..189883 Escherichia coli ATCC 8739 6068238 YP_001723182.1 CDS EcolC_0173 NC_010468.1 189893 190795 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_3541 dipeptide transport system permease protein 2; dipeptide transporter 189893..190795 Escherichia coli ATCC 8739 6068240 YP_001723183.1 CDS dppD NC_010468.1 190806 191789 D DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 190806..191789 Escherichia coli ATCC 8739 6068232 YP_001723184.1 CDS dppF NC_010468.1 191786 192790 D Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 191786..192790 Escherichia coli ATCC 8739 6068227 YP_001723185.1 CDS EcolC_0176 NC_010468.1 192820 194091 R TIGRFAM: serine transporter; KEGG: ssn:SSON_3851 putative transporter protein; serine transporter complement(192820..194091) Escherichia coli ATCC 8739 6065141 YP_001723186.1 CDS EcolC_0177 NC_010468.1 194567 194674 D KEGG: sfl:SF3572 hypothetical protein; hypothetical protein 194567..194674 Escherichia coli ATCC 8739 6068226 YP_001723187.1 CDS EcolC_0178 NC_010468.1 194761 196440 R KEGG: sfv:SFV_3549 hypothetical protein; hypothetical protein complement(194761..196440) Escherichia coli ATCC 8739 6068230 YP_001723188.1 CDS EcolC_0179 NC_010468.1 196437 196628 R KEGG: sfv:SFV_3550 hypothetical protein; hypothetical protein complement(196437..196628) Escherichia coli ATCC 8739 6065781 YP_001723189.1 CDS EcolC_0180 NC_010468.1 196625 198184 R KEGG: ssn:SSON_3854 putative protease; putative protease complement(196625..198184) Escherichia coli ATCC 8739 6064809 YP_001723190.1 CDS EcolC_0182 NC_010468.1 198469 198657 D KEGG: sbo:SBO_3534 hypothetical protein; hypothetical protein 198469..198657 Escherichia coli ATCC 8739 6067658 YP_001723191.1 CDS EcolC_0183 NC_010468.1 198669 199421 D TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: YhjQ family protein; KEGG: sfx:S4201 hypothetical protein; cell division protein 198669..199421 Escherichia coli ATCC 8739 6066202 YP_001723192.1 CDS bcsA NC_010468.1 199418 202036 D polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 199418..202036 Escherichia coli ATCC 8739 6068580 YP_001723193.1 CDS EcolC_0185 NC_010468.1 202077 204386 D binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 202077..204386 Escherichia coli ATCC 8739 6068243 YP_001723194.1 CDS EcolC_0186 NC_010468.1 204393 205499 D catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 204393..205499 Escherichia coli ATCC 8739 6068233 YP_001723195.1 CDS EcolC_0187 NC_010468.1 205481 208954 D cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 205481..208954 Escherichia coli ATCC 8739 6065574 YP_001723196.1 CDS EcolC_0188 NC_010468.1 209036 211024 D HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase 209036..211024 Escherichia coli ATCC 8739 6067284 YP_001723197.1 CDS EcolC_0189 NC_010468.1 211207 212493 D involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 211207..212493 Escherichia coli ATCC 8739 6064418 YP_001723198.1 CDS EcolC_0190 NC_010468.1 212714 214210 D PFAM: peptidase M16 domain protein; KEGG: sdy:SDY_4547 hypothetical protein; peptidase M16 domain-containing protein 212714..214210 Escherichia coli ATCC 8739 6067333 YP_001723199.1 CDS EcolC_0191 NC_010468.1 214306 215235 R PFAM: PfkB domain protein; KEGG: ssn:SSON_3865 ketodeoxygluconokinase; ribokinase-like domain-containing protein complement(214306..215235) Escherichia coli ATCC 8739 6066478 YP_001723200.1 CDS EcolC_0192 NC_010468.1 215467 216234 D in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 215467..216234 Escherichia coli ATCC 8739 6064461 YP_001723201.1 CDS EcolC_0193 NC_010468.1 216289 218364 D PFAM: AsmA family protein; KEGG: sbo:SBO_3523 hypothetical protein; AsmA family protein 216289..218364 Escherichia coli ATCC 8739 6064494 YP_001723202.1 CDS EcolC_0194 NC_010468.1 218546 219868 R TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3868 putative transport protein; major facilitator superfamily metabolite/H(+) symporter complement(218546..219868) Escherichia coli ATCC 8739 6064473 YP_001723203.1 CDS EcolC_0195 NC_010468.1 220279 221292 R TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: sbo:SBO_3521 hypothetical protein; ribonuclease complement(220279..221292) Escherichia coli ATCC 8739 6064518 YP_001723204.1 CDS EcolC_0196 NC_010468.1 221341 222312 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_3567 putative transcriptional regulator LysR-type; LysR family transcriptional regulator complement(221341..222312) Escherichia coli ATCC 8739 6066127 YP_001723205.1 CDS EcolC_0197 NC_010468.1 222760 223362 D PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: sbo:SBO_3519 putative regulator; two component LuxR family transcriptional regulator 222760..223362 Escherichia coli ATCC 8739 6065573 YP_001723206.1 CDS treF NC_010468.1 223413 225062 R cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase complement(223413..225062) Escherichia coli ATCC 8739 6065304 YP_001723207.1 CDS EcolC_0199 NC_010468.1 225467 226864 D PFAM: Di-haem cytochrome c peroxidase; KEGG: ssn:SSON_3568 putative cytochrome c peroxidase; cytochrome-c peroxidase 225467..226864 Escherichia coli ATCC 8739 6064526 YP_001723208.1 CDS EcolC_0200 NC_010468.1 227075 228475 D TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_3516 glutamate decarboxylase isozyme; glutamate decarboxylase 227075..228475 Escherichia coli ATCC 8739 6065432 YP_001723209.1 CDS EcolC_0201 NC_010468.1 228845 229669 D regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 228845..229669 Escherichia coli ATCC 8739 6065394 YP_001723210.1 CDS EcolC_0202 NC_010468.1 230037 230765 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_3987 putative AraC-type regulatory protein; AraC family transcriptional regulator 230037..230765 Escherichia coli ATCC 8739 6065541 YP_001723211.1 CDS EcolC_0203 NC_010468.1 231128 234241 R TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sdy:SDY_3537 putative transport system permease protein; hydrophobe/amphiphile efflux-1 (HAE1) family protein complement(231128..234241) Escherichia coli ATCC 8739 6065313 YP_001723212.1 CDS EcolC_0204 NC_010468.1 234266 235423 R with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE complement(234266..235423) Escherichia coli ATCC 8739 6064464 YP_001723213.1 CDS EcolC_0205 NC_010468.1 235762 236289 R KEGG: ssn:SSON_3574 hypothetical protein; LuxR family transcriptional regulator complement(235762..236289) Escherichia coli ATCC 8739 6064515 YP_001723214.1 CDS EcolC_0206 NC_010468.1 237088 237660 R KEGG: sbo:SBO_3510 hypothetical protein; acid-resistance membrane protein complement(237088..237660) Escherichia coli ATCC 8739 6065723 YP_001723215.1 CDS EcolC_0207 NC_010468.1 237915 238247 D inactive form; acid-resistance protein 237915..238247 Escherichia coli ATCC 8739 6065701 YP_001723216.1 CDS hdeB NC_010468.1 238363 238689 D KEGG: sbo:SBO_3508 hypothetical protein; acid-resistance protein 238363..238689 Escherichia coli ATCC 8739 6065999 YP_001723217.1 CDS EcolC_0209 NC_010468.1 238753 239400 D inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase 238753..239400 Escherichia coli ATCC 8739 6065823 YP_001723218.1 CDS EcolC_0210 NC_010468.1 239442 239972 R PFAM: regulatory protein LuxR; KEGG: ssn:SSON_3579 hypothetical protein; LuxR family transcriptional regulator complement(239442..239972) Escherichia coli ATCC 8739 6065555 YP_001723219.1 CDS EcolC_0211 NC_010468.1 240128 240694 R TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sbo:SBO_3505 Slp; Slp family outer membrane lipoprotein complement(240128..240694) Escherichia coli ATCC 8739 6066018 YP_001723220.1 CDS EcolC_0212 NC_010468.1 240942 242165 R KEGG: sfv:SFV_3519 hypothetical protein; hypothetical protein complement(240942..242165) Escherichia coli ATCC 8739 6066204 YP_001723221.1 CDS EcolC_0213 NC_010468.1 242794 243219 R KEGG: sbo:SBO_3501 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; arsenate reductase complement(242794..243219) Escherichia coli ATCC 8739 6066102 YP_001723222.1 CDS EcolC_0214 NC_010468.1 243232 244521 R TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein; arsenical pump membrane protein complement(243232..244521) Escherichia coli ATCC 8739 6066306 YP_001723223.1 CDS EcolC_0215 NC_010468.1 244575 244928 R regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR complement(244575..244928) Escherichia coli ATCC 8739 6066643 YP_001723224.1 CDS EcolC_0216 NC_010468.1 245805 247157 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(245805..247157) Escherichia coli ATCC 8739 6066517 YP_001723225.1 CDS EcolC_0217 NC_010468.1 247229 248071 R PFAM: protein of unknown function DUF519; KEGG: sbo:SBO_3497 hypothetical protein; hypothetical protein complement(247229..248071) Escherichia coli ATCC 8739 6066692 YP_001723226.1 CDS EcolC_0218 NC_010468.1 248274 250316 D PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: sbo:SBO_3496 oligopeptidase A; oligopeptidase A 248274..250316 Escherichia coli ATCC 8739 6066316 YP_001723227.1 CDS EcolC_0219 NC_010468.1 250324 251076 D predicted SAM-dependent methyltransferase; putative methyltransferase 250324..251076 Escherichia coli ATCC 8739 6066956 YP_001723228.1 CDS EcolC_0220 NC_010468.1 251125 252594 R member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP complement(251125..252594) Escherichia coli ATCC 8739 6066879 YP_001723229.1 CDS EcolC_0221 NC_010468.1 252912 253346 R PFAM: UspA domain protein; KEGG: cko:CKO_04943 hypothetical protein; UspA domain-containing protein complement(252912..253346) Escherichia coli ATCC 8739 6067060 YP_001723230.1 CDS EcolC_0222 NC_010468.1 253737 254072 D ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 253737..254072 Escherichia coli ATCC 8739 6066775 YP_001723231.1 CDS EcolC_0223 NC_010468.1 254317 255816 R PFAM: phosphate transporter; KEGG: sdy:SDY_3569 low-affinity phosphate transport; phosphate transporter complement(254317..255816) Escherichia coli ATCC 8739 6066098 YP_001723232.1 CDS EcolC_0224 NC_010468.1 256048 257250 D PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbo:SBO_3490 hypothetical protein; hypothetical protein 256048..257250 Escherichia coli ATCC 8739 6066217 YP_001723233.1 CDS EcolC_0225 NC_010468.1 257566 258618 R KEGG: sbo:SBO_3489 hypothetical protein; hypothetical protein complement(257566..258618) Escherichia coli ATCC 8739 6067195 YP_001723234.1 CDS EcolC_0226 NC_010468.1 259001 260608 D KEGG: sfl:SF3505 hypothetical protein; hypothetical protein 259001..260608 Escherichia coli ATCC 8739 6064538 YP_001723235.1 CDS EcolC_0227 NC_010468.1 260870 262492 D KEGG: ssn:SSON_3724 hypothetical protein; hypothetical protein 260870..262492 Escherichia coli ATCC 8739 6065186 YP_001723236.1 CDS EcolC_0228 NC_010468.1 262858 263925 D PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_3488 hypothetical protein; secretion protein HlyD family protein 262858..263925 Escherichia coli ATCC 8739 6064544 YP_001723237.1 CDS EcolC_0229 NC_010468.1 263922 266657 D PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase; KEGG: sfx:S4261 putative ATP-binding component of a transport system; ABC transporter-like protein 263922..266657 Escherichia coli ATCC 8739 6064543 YP_001723238.1 CDS EcolC_0230 NC_010468.1 266657 267781 D PFAM: ABC-2 type transporter; KEGG: sbo:SBO_3480 putative transporter; ABC-2 type transporter 266657..267781 Escherichia coli ATCC 8739 6067133 YP_001723239.1 CDS EcolC_0233 NC_010468.1 269678 270046 R hypothetical protein complement(269678..270046) Escherichia coli ATCC 8739 6067762 YP_001723240.1 CDS EcolC_0234 NC_010468.1 270033 274268 R TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(270033..274268) Escherichia coli ATCC 8739 6067783 YP_001723241.1 CDS EcolC_0235 NC_010468.1 274471 274872 R Inhibits transcription at high concentrations of nickel; nickel responsive regulator complement(274471..274872) Escherichia coli ATCC 8739 6067809 YP_001723242.1 CDS nikE NC_010468.1 274878 275684 R with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE complement(274878..275684) Escherichia coli ATCC 8739 6067803 YP_001723243.1 CDS nikD NC_010468.1 275681 276445 R with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD complement(275681..276445) Escherichia coli ATCC 8739 6067812 YP_001723244.1 CDS nikC NC_010468.1 276445 277278 R with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC complement(276445..277278) Escherichia coli ATCC 8739 6067790 YP_001723245.1 CDS EcolC_0239 NC_010468.1 277275 278219 R with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB complement(277275..278219) Escherichia coli ATCC 8739 6067826 YP_001723246.1 CDS EcolC_0240 NC_010468.1 278219 279793 R KEGG: sfx:S4269 periplasmic binding protein for nickel; TIGRFAM: nickel ABC transporter, periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5; nickel ABC transporter substrate-binding protein complement(278219..279793) Escherichia coli ATCC 8739 6067824 YP_001723247.1 CDS EcolC_0241 NC_010468.1 279904 280491 R PFAM: 4'-phosphopantetheinyl transferase; KEGG: sbo:SBO_3472 hypothetical protein; holo-(acyl carrier protein) synthase 2 complement(279904..280491) Escherichia coli ATCC 8739 6067832 YP_001723248.1 CDS EcolC_0242 NC_010468.1 280546 281595 R PFAM: protein of unknown function UPF0118; KEGG: ssn:SSON_3712 hypothetical protein; hypothetical protein complement(280546..281595) Escherichia coli ATCC 8739 6067818 YP_001723249.1 CDS EcolC_0243 NC_010468.1 281685 282944 D PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S4272 hypothetical protein; major facilitator superfamily transporter 281685..282944 Escherichia coli ATCC 8739 6067757 YP_001723250.1 CDS EcolC_0244 NC_010468.1 282948 283505 R KEGG: sdy:SDY_3623 hypothetical protein; hypothetical protein complement(282948..283505) Escherichia coli ATCC 8739 6067775 YP_001723251.1 CDS EcolC_0245 NC_010468.1 283578 284243 R TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: sfx:S4274 hypothetical protein; hypothetical protein complement(283578..284243) Escherichia coli ATCC 8739 6067845 YP_001723252.1 CDS EcolC_0246 NC_010468.1 284464 284709 D TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 284464..284709 Escherichia coli ATCC 8739 6067838 YP_001723253.1 CDS zntA NC_010468.1 284811 287009 R P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase complement(284811..287009) Escherichia coli ATCC 8739 6067856 YP_001723254.1 CDS EcolC_0248 NC_010468.1 287083 287709 R PFAM: YhhN family protein; KEGG: sfx:S4277 putative enzyme; hypothetical protein complement(287083..287709) Escherichia coli ATCC 8739 6067847 YP_001723255.1 CDS EcolC_0249 NC_010468.1 287850 288209 D KEGG: sbo:SBO_3464 putative receptor; putative receptor 287850..288209 Escherichia coli ATCC 8739 6067835 YP_001723256.1 CDS EcolC_0250 NC_010468.1 288212 288481 R PFAM: protein of unknown function DUF1145; KEGG: sdy:SDY_3617 hypothetical protein; hypothetical protein complement(288212..288481) Escherichia coli ATCC 8739 6067859 YP_001723257.1 CDS rsmD NC_010468.1 288471 289067 R catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase complement(288471..289067) Escherichia coli ATCC 8739 6067892 YP_001723258.1 CDS EcolC_0252 NC_010468.1 289217 290713 D signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 289217..290713 Escherichia coli ATCC 8739 6067884 YP_001723259.1 CDS EcolC_0253 NC_010468.1 290716 291384 D putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 290716..291384 Escherichia coli ATCC 8739 6067904 YP_001723260.1 CDS ftsX NC_010468.1 291377 292435 D putative ABC transporter, membrane protein; cell division protein FtsX 291377..292435 Escherichia coli ATCC 8739 6067944 YP_001723261.1 CDS EcolC_0255 NC_010468.1 292680 293534 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 292680..293534 Escherichia coli ATCC 8739 6067925 YP_001723262.1 CDS EcolC_0256 NC_010468.1 293805 294908 D PFAM: Extracellular ligand-binding receptor; KEGG: sbo:SBO_3457 high-affinity amino acid transport system periplasmic binding protein; extracellular ligand-binding receptor 293805..294908 Escherichia coli ATCC 8739 6067961 YP_001723263.1 CDS EcolC_0257 NC_010468.1 295107 295490 R PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_3456 hypothetical protein; N-acetyltransferase GCN5 complement(295107..295490) Escherichia coli ATCC 8739 6067911 YP_001723264.1 CDS EcolC_0258 NC_010468.1 295914 297023 D PFAM: Extracellular ligand-binding receptor; KEGG: sbo:SBO_3453 high-affinity leucine-specific transport system periplasmic binding protein; extracellular ligand-binding receptor 295914..297023 Escherichia coli ATCC 8739 6067977 YP_001723265.1 CDS EcolC_0259 NC_010468.1 297071 297997 D LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease LivH 297071..297997 Escherichia coli ATCC 8739 6067967 YP_001723266.1 CDS livM NC_010468.1 297994 299271 D Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease 297994..299271 Escherichia coli ATCC 8739 6067992 YP_001723267.1 CDS livG NC_010468.1 299268 300035 D Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 299268..300035 Escherichia coli ATCC 8739 6067964 YP_001723268.1 CDS livF NC_010468.1 300037 300750 D with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 300037..300750 Escherichia coli ATCC 8739 6067868 YP_001723269.1 CDS EcolC_0263 NC_010468.1 301147 302463 D with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 301147..302463 Escherichia coli ATCC 8739 6067899 YP_001723270.1 CDS EcolC_0264 NC_010468.1 302561 303448 D with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 302561..303448 Escherichia coli ATCC 8739 6068012 YP_001723271.1 CDS EcolC_0265 NC_010468.1 303445 304290 D with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 303445..304290 Escherichia coli ATCC 8739 6068009 YP_001723272.1 CDS ugpC NC_010468.1 304292 305362 D part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 304292..305362 Escherichia coli ATCC 8739 6068034 YP_001723273.1 CDS ugpQ NC_010468.1 305359 306102 D hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 305359..306102 Escherichia coli ATCC 8739 6068030 YP_001723274.1 CDS EcolC_0268 NC_010468.1 306089 306529 R KEGG: sbo:SBO_3444 hypothetical protein; hypothetical protein complement(306089..306529) Escherichia coli ATCC 8739 6068002 YP_001723275.1 CDS ggt NC_010468.1 306649 308391 D periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 306649..308391 Escherichia coli ATCC 8739 6066366 YP_001723276.1 CDS EcolC_0270 NC_010468.1 309253 309950 D PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein; insertion element protein join(309253..309507,309507..309950) Escherichia coli ATCC 8739 6068042 YP_001723277.1 CDS EcolC_0272 NC_010468.1 310533 311021 R YhhY; regulated by the fur regulator; unknown function; putative acetyltransferase YhhY complement(310533..311021) Escherichia coli ATCC 8739 6068066 YP_001723278.1 CDS EcolC_0273 NC_010468.1 311354 312391 D PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ssn:SSON_3682 putative regulator; putative dehydrogenase 311354..312391 Escherichia coli ATCC 8739 6065741 YP_001723279.1 CDS EcolC_0274 NC_010468.1 312514 313209 D PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: sbo:SBO_3436 hypothetical protein; pirin domain-containing protein 312514..313209 Escherichia coli ATCC 8739 6065872 YP_001723280.1 CDS EcolC_0275 NC_010468.1 313433 314428 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: cko:CKO_04857 hypothetical protein; LacI family transcriptional regulator 313433..314428 Escherichia coli ATCC 8739 6066444 YP_001723281.1 CDS gntK NC_010468.1 314606 315094 D thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 314606..315094 Escherichia coli ATCC 8739 6066791 YP_001723282.1 CDS EcolC_0277 NC_010468.1 315098 316438 D TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: sdy:SDY_3587 H+/gluconate symporter; low affinity gluconate transporter 315098..316438 Escherichia coli ATCC 8739 6064647 YP_001723283.1 CDS EcolC_0278 NC_010468.1 316495 317088 R YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase complement(316495..317088) Escherichia coli ATCC 8739 6065227 YP_001723284.1 CDS EcolC_0279 NC_010468.1 317280 318383 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 317280..318383 Escherichia coli ATCC 8739 6065307 YP_001723285.1 CDS EcolC_0280 NC_010468.1 318656 320842 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 318656..320842 Escherichia coli ATCC 8739 6065656 YP_001723286.1 CDS EcolC_0281 NC_010468.1 320839 322812 D catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 320839..322812 Escherichia coli ATCC 8739 6065822 YP_001723287.1 CDS glgC NC_010468.1 322830 324125 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 322830..324125 Escherichia coli ATCC 8739 6066105 YP_001723288.1 CDS glgA NC_010468.1 324125 325558 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 324125..325558 Escherichia coli ATCC 8739 6066262 YP_001723289.1 CDS EcolC_0284 NC_010468.1 325577 328024 D KEGG: sdy:SDY_3574 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; glycogen/starch/alpha-glucan phosphorylase 325577..328024 Escherichia coli ATCC 8739 6066846 YP_001723290.1 CDS EcolC_0285 NC_010468.1 328140 329657 D KEGG: ssn:SSON_3666 hypothetical membrane protein; hypothetical protein 328140..329657 Escherichia coli ATCC 8739 6067044 YP_001723291.1 CDS EcolC_0286 NC_010468.1 329683 330675 D KEGG: ssn:SSON_3666 hypothetical membrane protein; hypothetical protein 329683..330675 Escherichia coli ATCC 8739 6067696 YP_001723292.1 CDS EcolC_0287 NC_010468.1 330675 331277 D KEGG: sdy:SDY_3648 hypothetical protein; hypothetical protein 330675..331277 Escherichia coli ATCC 8739 6064696 YP_001723293.1 CDS glpD NC_010468.1 331493 332998 R in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase complement(331493..332998) Escherichia coli ATCC 8739 6064704 YP_001723294.1 CDS glpE NC_010468.1 333188 333514 D belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 333188..333514 Escherichia coli ATCC 8739 6065106 YP_001723295.1 CDS EcolC_0290 NC_010468.1 333559 334389 D protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 333559..334389 Escherichia coli ATCC 8739 6065483 YP_001723296.1 CDS EcolC_0291 NC_010468.1 334406 335164 D represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 334406..335164 Escherichia coli ATCC 8739 6065820 YP_001723297.1 CDS EcolC_0292 NC_010468.1 335146 336744 R PFAM: sigma-54 factor interaction domain-containing protein; regulator of RNA terminal phosphate cyclase; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sfv:SFV_3429 putative 2-component regulator; regulator of RNA terminal phosphate cyclase complement(335146..336744) Escherichia coli ATCC 8739 6066844 YP_001723298.1 CDS EcolC_0293 NC_010468.1 336932 338158 D PFAM: protein of unknown function UPF0027; KEGG: sfv:SFV_3428 hypothetical protein; hypothetical protein 336932..338158 Escherichia coli ATCC 8739 6067522 YP_001723299.1 CDS EcolC_0294 NC_010468.1 338162 339178 D catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 338162..339178 Escherichia coli ATCC 8739 6067601 YP_001723300.1 CDS EcolC_0295 NC_010468.1 339221 341926 R Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT complement(339221..341926) Escherichia coli ATCC 8739 6064393 YP_001723301.1 CDS EcolC_0296 NC_010468.1 342538 344931 D KEGG: ssn:SSON_3549 maltodextrin phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; glycogen/starch/alpha-glucan phosphorylase 342538..344931 Escherichia coli ATCC 8739 6065748 YP_001723302.1 CDS malQ NC_010468.1 344941 347025 D amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 344941..347025 Escherichia coli ATCC 8739 6064621 YP_001723303.1 CDS EcolC_0298 NC_010468.1 347070 348386 R TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: sbo:SBO_3404 high-affinity transport of gluconate/gluconate permease; gluconate transporter complement(347070..348386) Escherichia coli ATCC 8739 6067888 YP_001723304.1 CDS EcolC_0299 NC_010468.1 348747 349322 R cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein complement(348747..349322) Escherichia coli ATCC 8739 6067894 YP_001723305.1 CDS EcolC_0300 NC_010468.1 349381 350064 R involved in high-affinity gluconate transport; gluconate periplasmic binding protein complement(349381..350064) Escherichia coli ATCC 8739 6066128 YP_001723306.1 CDS EcolC_0301 NC_010468.1 350102 350872 D Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 350102..350872 Escherichia coli ATCC 8739 6066180 YP_001723307.1 CDS EcolC_0302 NC_010468.1 350901 351779 R PFAM: putative transposase YhgA family protein; KEGG: sbo:SBO_3400 hypothetical protein; hypothetical protein complement(350901..351779) Escherichia coli ATCC 8739 6066251 YP_001723308.1 CDS EcolC_0303 NC_010468.1 351982 352218 R PFAM: Protein of unknown function DUF1920; KEGG: ssn:SSON_3541 hypothetical protein; hypothetical protein complement(351982..352218) Escherichia coli ATCC 8739 6066188 YP_001723309.1 CDS feoB NC_010468.1 352218 354539 R cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B complement(352218..354539) Escherichia coli ATCC 8739 6065200 YP_001723310.1 CDS feoA NC_010468.1 354556 354783 R PFAM: FeoA family protein; KEGG: sdy:SDY_3668 ferrous iron transport protein A; ferrous iron transport protein A complement(354556..354783) Escherichia coli ATCC 8739 6064864 YP_001723311.1 CDS EcolC_0306 NC_010468.1 355221 357542 R PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: sfv:SFV_3412 hypothetical protein; RNA-binding S1 domain-containing protein complement(355221..357542) Escherichia coli ATCC 8739 6064867 YP_001723312.1 CDS greB NC_010468.1 357639 358115 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(357639..358115) Escherichia coli ATCC 8739 6064991 YP_001723313.1 CDS ompR NC_010468.1 358343 359062 D part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 358343..359062 Escherichia coli ATCC 8739 6065427 YP_001723314.1 CDS envZ NC_010468.1 359059 360411 D membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 359059..360411 Escherichia coli ATCC 8739 6065497 YP_001723315.1 CDS EcolC_0310 NC_010468.1 360487 362109 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(360487..362109) Escherichia coli ATCC 8739 6065068 YP_001723316.1 CDS EcolC_0311 NC_010468.1 362488 364212 D KEGG: sbo:SBO_3389 putative transport; putative transport protein 362488..364212 Escherichia coli ATCC 8739 6065954 YP_001723317.1 CDS hslO NC_010468.1 364275 365159 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(364275..365159) Escherichia coli ATCC 8739 6066790 YP_001723318.1 CDS EcolC_0313 NC_010468.1 365178 365579 R PFAM: RNA-binding S4 domain protein; KEGG: sdy:SDY_3678 hypothetical protein; ribosome-associated heat shock protein Hsp15 complement(365178..365579) Escherichia coli ATCC 8739 6065293 YP_001723319.1 CDS EcolC_0314 NC_010468.1 365590 366258 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdy:SDY_3679 putative phosphatase; HAD family hydrolase complement(365590..366258) Escherichia coli ATCC 8739 6066864 YP_001723320.1 CDS EcolC_0315 NC_010468.1 366323 368458 R PFAM: Intracellular growth attenuator IgaA; KEGG: sfv:SFV_3403 putative dehydrogenase; intracellular growth attenuator IgaA complement(366323..368458) Escherichia coli ATCC 8739 6066344 YP_001723321.1 CDS nudE NC_010468.1 368778 369338 D ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 368778..369338 Escherichia coli ATCC 8739 6066035 YP_001723322.1 CDS mrcA NC_010468.1 369506 372058 R bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase complement(369506..372058) Escherichia coli ATCC 8739 6065992 YP_001723323.1 CDS EcolC_0318 NC_010468.1 372178 372957 D KEGG: sfv:SFV_3400 hypothetical protein; hypothetical protein 372178..372957 Escherichia coli ATCC 8739 6065739 YP_001723324.1 CDS EcolC_0319 NC_010468.1 372957 373496 D PFAM: Fimbrial assembly family protein; KEGG: sfv:SFV_3399 hypothetical protein; fimbrial assembly family protein 372957..373496 Escherichia coli ATCC 8739 6067405 YP_001723325.1 CDS EcolC_0320 NC_010468.1 373480 373920 D KEGG: sfv:SFV_3398 hypothetical protein; hypothetical protein 373480..373920 Escherichia coli ATCC 8739 6068742 YP_001723326.1 CDS EcolC_0321 NC_010468.1 373910 374314 D KEGG: sdy:SDY_3687 hypothetical protein; hypothetical protein 373910..374314 Escherichia coli ATCC 8739 6067271 YP_001723327.1 CDS hofQ NC_010468.1 374304 375464 D outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 374304..375464 Escherichia coli ATCC 8739 6065266 YP_001723328.1 CDS aroK NC_010468.1 375865 376386 D type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 375865..376386 Escherichia coli ATCC 8739 6065347 YP_001723329.1 CDS aroB NC_010468.1 376443 377531 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 376443..377531 Escherichia coli ATCC 8739 6065354 YP_001723330.1 CDS EcolC_0325 NC_010468.1 377623 378909 D PFAM: Sporulation domain protein; KEGG: sbo:SBO_3375 DamX; hypothetical protein 377623..378909 Escherichia coli ATCC 8739 6065381 YP_001723331.1 CDS EcolC_0326 NC_010468.1 379016 379852 D KEGG: sbo:SBO_3374 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; DNA adenine methylase 379016..379852 Escherichia coli ATCC 8739 6065416 YP_001723332.1 CDS EcolC_0327 NC_010468.1 379870 380547 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 379870..380547 Escherichia coli ATCC 8739 6065470 YP_001723333.1 CDS EcolC_0328 NC_010468.1 380540 381298 D catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 380540..381298 Escherichia coli ATCC 8739 6065474 YP_001723334.1 CDS EcolC_0329 NC_010468.1 381291 382295 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 381291..382295 Escherichia coli ATCC 8739 6065522 YP_001723335.1 CDS EcolC_0330 NC_010468.1 382585 383490 D KEGG: cko:CKO_04803 hypothetical protein; hypothetical protein 382585..383490 Escherichia coli ATCC 8739 6065551 YP_001723336.1 CDS EcolC_0331 NC_010468.1 383507 383869 D KEGG: sbo:SBO_3369 hypothetical protein; hypothetical protein 383507..383869 Escherichia coli ATCC 8739 6065554 YP_001723337.1 CDS EcolC_0332 NC_010468.1 383953 385116 D PFAM: alanine racemase domain protein; KEGG: sbo:SBO_3368 hypothetical protein; alanine racemase domain-containing protein 383953..385116 Escherichia coli ATCC 8739 6065562 YP_001723338.1 CDS EcolC_0333 NC_010468.1 385116 386342 D PFAM: metalloenzyme domain protein; Phosphopentomutase domain protein; KEGG: sfv:SFV_3385 putative mutase; putative mutase 385116..386342 Escherichia coli ATCC 8739 6065569 YP_001723339.1 CDS EcolC_0334 NC_010468.1 386339 387217 D phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase 386339..387217 Escherichia coli ATCC 8739 6065603 YP_001723340.1 CDS EcolC_0335 NC_010468.1 387228 387581 D KEGG: sfv:SFV_3383 hypothetical protein; hypothetical protein 387228..387581 Escherichia coli ATCC 8739 6065607 YP_001723341.1 CDS EcolC_0336 NC_010468.1 387593 388897 D KEGG: sfx:S4367 putative transport system permease protein; putative transport system permease 387593..388897 Escherichia coli ATCC 8739 6065652 YP_001723342.1 CDS EcolC_0337 NC_010468.1 388909 389994 D KEGG: sbo:SBO_3363 hypothetical protein; GntR family transcriptional regulator 388909..389994 Escherichia coli ATCC 8739 6065661 YP_001723343.1 CDS EcolC_0338 NC_010468.1 390146 390877 R may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR complement(390146..390877) Escherichia coli ATCC 8739 6065669 YP_001723344.1 CDS EcolC_0339 NC_010468.1 390977 391762 R PFAM: PfkB domain protein; KEGG: sfv:SFV_3379 putative kinase; fructoselysine 6-kinase complement(390977..391762) Escherichia coli ATCC 8739 6065750 YP_001723345.1 CDS EcolC_0340 NC_010468.1 391759 392589 R YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase complement(391759..392589) Escherichia coli ATCC 8739 6065779 YP_001723346.1 CDS frlB NC_010468.1 392639 393661 R catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase complement(392639..393661) Escherichia coli ATCC 8739 6065791 YP_001723347.1 CDS frlA NC_010468.1 393682 395019 R inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter complement(393682..395019) Escherichia coli ATCC 8739 6065819 YP_001723348.1 CDS EcolC_0343 NC_010468.1 395314 395481 R KEGG: sbo:SBO_3357 hypothetical protein; hypothetical protein complement(395314..395481) Escherichia coli ATCC 8739 6065868 YP_001723349.1 CDS cysG NC_010468.1 395728 397101 R multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase complement(395728..397101) Escherichia coli ATCC 8739 6065889 YP_001723350.1 CDS EcolC_0345 NC_010468.1 397120 397926 R member of the FNT family of formate and nitrite transporters; nitrite transporter NirC complement(397120..397926) Escherichia coli ATCC 8739 6065909 YP_001723351.1 CDS nirD NC_010468.1 398053 398379 R involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit complement(398053..398379) Escherichia coli ATCC 8739 6065938 YP_001723352.1 CDS EcolC_0347 NC_010468.1 398376 400919 R TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ssn:SSON_3496 nitrite reductase (NAD(P)H) subunit; nitrite reductase (NAD(P)H) large subunit complement(398376..400919) Escherichia coli ATCC 8739 6065965 YP_001723353.1 CDS EcolC_0348 NC_010468.1 401181 402362 R PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_3346 putative transport; hypothetical protein complement(401181..402362) Escherichia coli ATCC 8739 6065975 YP_001723354.1 CDS EcolC_0349 NC_010468.1 402633 403205 D PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ssn:SSON_3494 peptidyl-prolyl cis-trans isomerase A; peptidyl-prolyl cis-trans isomerase A 402633..403205 Escherichia coli ATCC 8739 6066003 YP_001723355.1 CDS EcolC_0350 NC_010468.1 403310 403477 D KEGG: ssn:SSON_3493 hypothetical protein; hypothetical protein 403310..403477 Escherichia coli ATCC 8739 6066032 YP_001723356.1 CDS EcolC_0351 NC_010468.1 403467 404069 D PFAM: filamentation induced by cAMP protein Fic; KEGG: sfv:SFV_3367 cell filamentation protein fic; cell filamentation protein Fic 403467..404069 Escherichia coli ATCC 8739 6066061 YP_001723357.1 CDS EcolC_0352 NC_010468.1 404101 404664 D aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 404101..404664 Escherichia coli ATCC 8739 6066078 YP_001723358.1 CDS argD NC_010468.1 404750 405970 D DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 404750..405970 Escherichia coli ATCC 8739 6066091 YP_001723359.1 CDS EcolC_0354 NC_010468.1 406037 408127 R TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_3489 hypothetical protein; YccS/YhfK family integral membrane protein complement(406037..408127) Escherichia coli ATCC 8739 6066096 YP_001723360.1 CDS EcolC_0355 NC_010468.1 408178 408810 R complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein complement(408178..408810) Escherichia coli ATCC 8739 6066107 YP_001723361.1 CDS EcolC_0356 NC_010468.1 409112 409516 D PFAM: OsmC family protein; KEGG: sdy:SDY_3518 hypothetical protein; hypothetical protein 409112..409516 Escherichia coli ATCC 8739 6066115 YP_001723362.1 CDS EcolC_0357 NC_010468.1 409571 410440 R PFAM: phosphoribulokinase/uridine kinase; KEGG: sbo:SBO_3335 probable phosphoribulokinase; phosphoribulokinase complement(409571..410440) Escherichia coli ATCC 8739 6066126 YP_001723363.1 CDS EcolC_0358 NC_010468.1 410494 410712 R PFAM: protein of unknown function UPF0270; KEGG: sbo:SBO_3334 hypothetical protein; hypothetical protein complement(410494..410712) Escherichia coli ATCC 8739 6066194 YP_001723364.1 CDS EcolC_0359 NC_010468.1 410706 411728 R PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_3484 hypothetical protein; putative hydrolase complement(410706..411728) Escherichia coli ATCC 8739 6066222 YP_001723365.1 CDS EcolC_0360 NC_010468.1 411728 413641 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_3483 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein complement(411728..413641) Escherichia coli ATCC 8739 6066261 YP_001723366.1 CDS EcolC_0361 NC_010468.1 413772 414323 D required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 413772..414323 Escherichia coli ATCC 8739 6066267 YP_001723367.1 CDS EcolC_0362 NC_010468.1 414323 416128 D involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 414323..416128 Escherichia coli ATCC 8739 6066286 YP_001723368.1 CDS EcolC_0363 NC_010468.1 416138 416338 D PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3511 hypothetical protein; hypothetical protein 416138..416338 Escherichia coli ATCC 8739 6066323 YP_001723369.1 CDS EcolC_0364 NC_010468.1 416433 417023 D rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 416433..417023 Escherichia coli ATCC 8739 6066359 YP_001723370.1 CDS EcolC_0365 NC_010468.1 417072 417290 R PFAM: SlyX family protein; KEGG: sdy:SDY_3509 host factor for lysis of phiX174 infection; hypothetical protein complement(417072..417290) Escherichia coli ATCC 8739 6066368 YP_001723371.1 CDS EcolC_0366 NC_010468.1 417511 418323 D rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 417511..418323 Escherichia coli ATCC 8739 6066379 YP_001723372.1 CDS EcolC_0367 NC_010468.1 418490 419212 D PFAM: YheO domain protein; KEGG: sbo:SBO_3326 hypothetical protein; YheO domain-containing protein 418490..419212 Escherichia coli ATCC 8739 6066396 YP_001723373.1 CDS EcolC_0368 NC_010468.1 419212 419598 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 419212..419598 Escherichia coli ATCC 8739 6066408 YP_001723374.1 CDS EcolC_0369 NC_010468.1 419598 419957 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 419598..419957 Escherichia coli ATCC 8739 6066421 YP_001723375.1 CDS EcolC_0370 NC_010468.1 419965 420252 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 419965..420252 Escherichia coli ATCC 8739 6066429 YP_001723376.1 CDS rpsL NC_010468.1 420378 420752 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 420378..420752 Escherichia coli ATCC 8739 6066439 YP_001723377.1 CDS EcolC_0372 NC_010468.1 420849 421319 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 420849..421319 Escherichia coli ATCC 8739 6066482 YP_001723378.1 CDS EcolC_0373 NC_010468.1 421416 423530 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 421416..423530 Escherichia coli ATCC 8739 6066502 YP_001723379.1 CDS EcolC_0374 NC_010468.1 423601 424785 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 423601..424785 Escherichia coli ATCC 8739 6066530 YP_001723380.1 CDS EcolC_0375 NC_010468.1 425077 427770 D PFAM: Carbohydrate-binding family V/XII; KEGG: cbh:CLC_1134 putative glycosyl hydrolase; lysozyme 425077..427770 Escherichia coli ATCC 8739 6066557 YP_001723381.1 CDS EcolC_0376 NC_010468.1 427939 428133 D PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: cko:CKO_04744 hypothetical protein; bacterioferritin-associated ferredoxin 427939..428133 Escherichia coli ATCC 8739 6066591 YP_001723382.1 CDS EcolC_0377 NC_010468.1 428205 428681 D iron storage protein; bacterioferritin 428205..428681 Escherichia coli ATCC 8739 6066615 YP_001723383.1 CDS EcolC_0378 NC_010468.1 428710 429387 R PFAM: peptidase A24A prepilin type IV; KEGG: kpn:KPN_00149 pullulanase Q protein; peptidase A24A prepilin type IV complement(428710..429387) Escherichia coli ATCC 8739 6066623 YP_001723384.1 CDS EcolC_0379 NC_010468.1 429387 429848 R PFAM: General secretion pathway M protein; general secretion pathway M protein complement(429387..429848) Escherichia coli ATCC 8739 6066626 YP_001723385.1 CDS EcolC_0380 NC_010468.1 429845 431008 R TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: cko:CKO_02220 hypothetical protein; general secretion pathway protein L complement(429845..431008) Escherichia coli ATCC 8739 6066666 YP_001723386.1 CDS EcolC_0381 NC_010468.1 431023 432006 R PFAM: General secretion pathway protein K; KEGG: eca:ECA3102 general secretion pathway protein K; general secretion pathway protein K complement(431023..432006) Escherichia coli ATCC 8739 6066693 YP_001723387.1 CDS EcolC_0382 NC_010468.1 431999 432586 R TIGRFAM: general secretion pathway protein J; KEGG: vpa:VP0139 general secretion pathway protein J; general secretion pathway protein J complement(431999..432586) Escherichia coli ATCC 8739 6066733 YP_001723388.1 CDS EcolC_0383 NC_010468.1 432579 432956 R TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: pap:PSPA7_2034 general secretion pathway protein I; general secretion pathway protein I complement(432579..432956) Escherichia coli ATCC 8739 6066738 YP_001723389.1 CDS EcolC_0384 NC_010468.1 432953 433462 R TIGRFAM: general secretion pathway protein H; KEGG: kpn:KPN_00156 pullulanase H protein; general secretion pathway protein H complement(432953..433462) Escherichia coli ATCC 8739 6066742 YP_001723390.1 CDS EcolC_0385 NC_010468.1 433470 433907 R TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: cko:CKO_02225 hypothetical protein; general secretion pathway protein G complement(433470..433907) Escherichia coli ATCC 8739 6066750 YP_001723391.1 CDS EcolC_0386 NC_010468.1 433917 435113 R TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: cko:CKO_02226 hypothetical protein; general secretion pathway protein F complement(433917..435113) Escherichia coli ATCC 8739 6066755 YP_001723392.1 CDS EcolC_0387 NC_010468.1 435110 436591 R KEGG: cko:CKO_02227 hypothetical protein; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase; general secretory pathway protein E complement(435110..436591) Escherichia coli ATCC 8739 6066774 YP_001723393.1 CDS EcolC_0388 NC_010468.1 436601 438565 R TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: cko:CKO_02228 hypothetical protein; general secretion pathway protein D complement(436601..438565) Escherichia coli ATCC 8739 6066786 YP_001723394.1 CDS EcolC_0389 NC_010468.1 438537 439352 R TIGRFAM: general secretion pathway protein C; KEGG: kpn:KPN_00161 pullulanase C protein; general secretion pathway protein C complement(438537..439352) Escherichia coli ATCC 8739 6066816 YP_001723395.1 CDS EcolC_0390 NC_010468.1 439532 441001 D PFAM: Peptidoglycan-binding domain 1 protein; KEGG: cko:CKO_02233 hypothetical protein; peptidoglycan binding domain-containing protein 439532..441001 Escherichia coli ATCC 8739 6066836 YP_001723396.1 CDS EcolC_0391 NC_010468.1 441003 441422 D calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 441003..441422 Escherichia coli ATCC 8739 6066861 YP_001723397.1 CDS rpsJ NC_010468.1 441660 441971 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 441660..441971 Escherichia coli ATCC 8739 6066873 YP_001723398.1 CDS rplC NC_010468.1 442004 442633 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 442004..442633 Escherichia coli ATCC 8739 6066884 YP_001723399.1 CDS rplD NC_010468.1 442644 443249 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 442644..443249 Escherichia coli ATCC 8739 6066899 YP_001723400.1 CDS rplW NC_010468.1 443246 443548 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 443246..443548 Escherichia coli ATCC 8739 6066907 YP_001723401.1 CDS rplB NC_010468.1 443566 444387 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 443566..444387 Escherichia coli ATCC 8739 6066928 YP_001723402.1 CDS rpsS NC_010468.1 444404 444682 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 444404..444682 Escherichia coli ATCC 8739 6066940 YP_001723403.1 CDS rplV NC_010468.1 444697 445029 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 444697..445029 Escherichia coli ATCC 8739 6066953 YP_001723404.1 CDS rpsC NC_010468.1 445047 445748 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 445047..445748 Escherichia coli ATCC 8739 6066973 YP_001723405.1 CDS rplP NC_010468.1 445761 446171 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 445761..446171 Escherichia coli ATCC 8739 6067014 YP_001723406.1 CDS EcolC_0401 NC_010468.1 446171 446362 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 446171..446362 Escherichia coli ATCC 8739 6067062 YP_001723407.1 CDS rpsQ NC_010468.1 446362 446616 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 446362..446616 Escherichia coli ATCC 8739 6067115 YP_001723408.1 CDS rplN NC_010468.1 446781 447152 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 446781..447152 Escherichia coli ATCC 8739 6067146 YP_001723409.1 CDS rplX NC_010468.1 447163 447477 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 447163..447477 Escherichia coli ATCC 8739 6067186 YP_001723410.1 CDS rplE NC_010468.1 447492 448031 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 447492..448031 Escherichia coli ATCC 8739 6067191 YP_001723411.1 CDS rpsN NC_010468.1 448046 448351 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 448046..448351 Escherichia coli ATCC 8739 6067218 YP_001723412.1 CDS rpsH NC_010468.1 448385 448777 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 448385..448777 Escherichia coli ATCC 8739 6067299 YP_001723413.1 CDS rplF NC_010468.1 448790 449323 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 448790..449323 Escherichia coli ATCC 8739 6067337 YP_001723414.1 CDS rplR NC_010468.1 449333 449686 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 449333..449686 Escherichia coli ATCC 8739 6067341 YP_001723415.1 CDS rpsE NC_010468.1 449701 450204 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 449701..450204 Escherichia coli ATCC 8739 6067346 YP_001723416.1 CDS rpmD NC_010468.1 450208 450387 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 450208..450387 Escherichia coli ATCC 8739 6067375 YP_001723417.1 CDS rplO NC_010468.1 450391 450825 D late assembly protein; 50S ribosomal protein L15 450391..450825 Escherichia coli ATCC 8739 6067402 YP_001723418.1 CDS secY NC_010468.1 450833 452164 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 450833..452164 Escherichia coli ATCC 8739 6067423 YP_001723419.1 CDS rpmJ NC_010468.1 452196 452312 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 452196..452312 Escherichia coli ATCC 8739 6067490 YP_001723420.1 CDS rpsM NC_010468.1 452459 452815 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 452459..452815 Escherichia coli ATCC 8739 6067510 YP_001723421.1 CDS EcolC_0416 NC_010468.1 452832 453221 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 452832..453221 Escherichia coli ATCC 8739 6067533 YP_001723422.1 CDS rpsD NC_010468.1 453255 453875 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 453255..453875 Escherichia coli ATCC 8739 6067536 YP_001723423.1 CDS EcolC_0418 NC_010468.1 453901 454890 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 453901..454890 Escherichia coli ATCC 8739 6067559 YP_001723424.1 CDS rplQ NC_010468.1 454931 455314 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 454931..455314 Escherichia coli ATCC 8739 6067585 YP_001723425.1 CDS EcolC_0420 NC_010468.1 455421 455789 D KEGG: ssn:SSON_3434 hypothetical protein; hypothetical protein 455421..455789 Escherichia coli ATCC 8739 6067590 YP_001723426.1 CDS zntR NC_010468.1 455800 456225 D mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 455800..456225 Escherichia coli ATCC 8739 6067620 YP_001723427.1 CDS EcolC_0422 NC_010468.1 456281 456499 D PFAM: protein of unknown function DUF331; KEGG: ssn:SSON_3432 hypothetical protein; hypothetical protein 456281..456499 Escherichia coli ATCC 8739 6067630 YP_001723428.1 CDS mscL NC_010468.1 456496 456906 R forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel complement(456496..456906) Escherichia coli ATCC 8739 6067654 YP_001723429.1 CDS trkA NC_010468.1 457036 458412 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein complement(457036..458412) Escherichia coli ATCC 8739 6067682 YP_001723430.1 CDS EcolC_0425 NC_010468.1 458434 459723 R catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B complement(458434..459723) Escherichia coli ATCC 8739 6067698 YP_001723431.1 CDS fmt NC_010468.1 459769 460716 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(459769..460716) Escherichia coli ATCC 8739 6067707 YP_001723432.1 CDS def NC_010468.1 460731 461240 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(460731..461240) Escherichia coli ATCC 8739 6067709 YP_001723433.1 CDS EcolC_0428 NC_010468.1 461370 462494 D TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: sdy:SDY_3462 predicted Rossmann-fold nucleotide-binding protein; DNA protecting protein DprA 461370..462494 Escherichia coli ATCC 8739 6067714 YP_001723434.1 CDS EcolC_0429 NC_010468.1 462466 462939 D PFAM: protein of unknown function DUF494; KEGG: sbo:SBO_3278 hypothetical protein; hypothetical protein 462466..462939 Escherichia coli ATCC 8739 6067721 YP_001723435.1 CDS EcolC_0430 NC_010468.1 462968 463510 D PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: sdy:SDY_3460 putative DNA topoisomerase; DNA topoisomerase type IA Zn finger domain-containing protein 462968..463510 Escherichia coli ATCC 8739 6067724 YP_001723436.1 CDS EcolC_0431 NC_010468.1 463515 464087 D RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor 463515..464087 Escherichia coli ATCC 8739 6067727 YP_001723437.1 CDS aroE NC_010468.1 464092 464910 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 464092..464910 Escherichia coli ATCC 8739 6067735 YP_001723438.1 CDS EcolC_0433 NC_010468.1 464907 465164 D PFAM: protein of unknown function DUF1488; KEGG: sbo:SBO_3274 hypothetical protein; hypothetical protein 464907..465164 Escherichia coli ATCC 8739 6067737 YP_001723439.1 CDS EcolC_0434 NC_010468.1 465140 465694 R KEGG: ssn:SSON_3420 putative transferase; putative transferase complement(465140..465694) Escherichia coli ATCC 8739 6067740 YP_001723440.1 CDS EcolC_0435 NC_010468.1 471747 472505 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_3265 putative ATP-binding component of a transport system; ABC transporter-like protein complement(471747..472505) Escherichia coli ATCC 8739 6067863 YP_001723441.1 CDS EcolC_0436 NC_010468.1 472513 473616 R TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_3447 putative transport system permease protein; polar amino acid ABC transporter inner membrane protein complement(472513..473616) Escherichia coli ATCC 8739 6067883 YP_001723442.1 CDS EcolC_0437 NC_010468.1 473626 474807 R TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cko:CKO_04682 hypothetical protein; polar amino acid ABC transporter inner membrane protein complement(473626..474807) Escherichia coli ATCC 8739 6067910 YP_001723443.1 CDS EcolC_0438 NC_010468.1 474875 475900 R SMART: extracellular solute-binding protein family 3; KEGG: sfv:SFV_3290 putative periplasmic binding transport protein; extracellular solute-binding protein complement(474875..475900) Escherichia coli ATCC 8739 6067924 YP_001723444.1 CDS EcolC_0439 NC_010468.1 476331 476552 R KEGG: stm:STM3392 putative outer membrane lipoprotein; putative outer membrane lipoprotein complement(476331..476552) Escherichia coli ATCC 8739 6067945 YP_001723445.1 CDS EcolC_0440 NC_010468.1 476805 479909 R TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_3260 integral transmembrane protein; hydrophobe/amphiphile efflux-1 (HAE1) family protein complement(476805..479909) Escherichia coli ATCC 8739 6067962 YP_001723446.1 CDS EcolC_0441 NC_010468.1 479921 481078 R TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_3406 AcrE; RND family efflux transporter MFP subunit complement(479921..481078) Escherichia coli ATCC 8739 6067987 YP_001723447.1 CDS EcolC_0442 NC_010468.1 481477 482139 D PFAM: regulatory protein TetR; Tetracycline transcriptional repressor MAATS-type domain protein; KEGG: sbo:SBO_3258 putative transcriptional regulator; DNA-binding transcriptional regulator EnvR 481477..482139 Escherichia coli ATCC 8739 6068022 YP_001723448.1 CDS EcolC_0443 NC_010468.1 482142 482321 R KEGG: sbo:SBO_3257 hypothetical protein; hypothetical protein complement(482142..482321) Escherichia coli ATCC 8739 6068150 YP_001723449.1 CDS EcolC_0444 NC_010468.1 482405 483289 R PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ssn:SSON_3403 putative methyltransferase; putative methyltransferase complement(482405..483289) Escherichia coli ATCC 8739 6068168 YP_001723450.1 CDS fis NC_010468.1 483375 483671 R Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis complement(483375..483671) Escherichia coli ATCC 8739 6068175 YP_001723451.1 CDS EcolC_0446 NC_010468.1 483697 484662 R TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: sdy:SDY_3437 putative dehydrogenase; tRNA-dihydrouridine synthase B complement(483697..484662) Escherichia coli ATCC 8739 6068193 YP_001723452.1 CDS prmA NC_010468.1 484991 485872 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(484991..485872) Escherichia coli ATCC 8739 6068197 YP_001723453.1 CDS panF NC_010468.1 485884 487335 R mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter complement(485884..487335) Escherichia coli ATCC 8739 6068209 YP_001723454.1 CDS EcolC_0449 NC_010468.1 487325 487567 R PFAM: protein of unknown function DUF997; KEGG: sdy:SDY_3434 hypothetical protein; hypothetical protein complement(487325..487567) Escherichia coli ATCC 8739 6068215 YP_001723455.1 CDS EcolC_0450 NC_010468.1 487676 489025 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit complement(487676..489025) Escherichia coli ATCC 8739 6068219 YP_001723456.1 CDS EcolC_0451 NC_010468.1 489036 489506 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(489036..489506) Escherichia coli ATCC 8739 6068228 YP_001723457.1 CDS EcolC_0453 NC_010468.1 490372 491202 R KEGG: sdy:SDY_3429 hypothetical protein; hypothetical protein complement(490372..491202) Escherichia coli ATCC 8739 6068241 YP_001723458.1 CDS EcolC_0454 NC_010468.1 491239 492213 R TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_3394 putative dehydrogenase; quinone oxidoreductase complement(491239..492213) Escherichia coli ATCC 8739 6068254 YP_001723459.1 CDS EcolC_0455 NC_010468.1 492365 494305 D regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 492365..494305 Escherichia coli ATCC 8739 6068260 YP_001723460.1 CDS EcolC_0456 NC_010468.1 494610 495653 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 494610..495653 Escherichia coli ATCC 8739 6068287 YP_001723461.1 CDS EcolC_0457 NC_010468.1 495719 496822 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 495719..496822 Escherichia coli ATCC 8739 6068294 YP_001723462.1 CDS EcolC_0458 NC_010468.1 496822 497310 D part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 496822..497310 Escherichia coli ATCC 8739 6068301 YP_001723463.1 CDS EcolC_0459 NC_010468.1 497319 497912 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 497319..497912 Escherichia coli ATCC 8739 6068308 YP_001723464.1 CDS EcolC_0460 NC_010468.1 497902 499371 D involved in the processing of the 5'end of 16S rRNA; ribonuclease G 497902..499371 Escherichia coli ATCC 8739 6068313 YP_001723465.1 CDS EcolC_0461 NC_010468.1 499439 503239 D KEGG: ssn:SSON_3387 uncharacterized membrane protein; hypothetical protein 499439..503239 Escherichia coli ATCC 8739 6068318 YP_001723466.1 CDS tldD NC_010468.1 503669 505114 D responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 503669..505114 Escherichia coli ATCC 8739 6068338 YP_001723467.1 CDS EcolC_0463 NC_010468.1 505248 506177 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3144 QseA; putative DNA-binding transcriptional regulator complement(505248..506177) Escherichia coli ATCC 8739 6068345 YP_001723468.1 CDS EcolC_0464 NC_010468.1 506360 506563 D membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 506360..506563 Escherichia coli ATCC 8739 6068349 YP_001723469.1 CDS EcolC_0465 NC_010468.1 506571 507503 D with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 506571..507503 Escherichia coli ATCC 8739 6068351 YP_001723470.1 CDS EcolC_0466 NC_010468.1 507509 509476 D with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 507509..509476 Escherichia coli ATCC 8739 6068357 YP_001723471.1 CDS EcolC_0467 NC_010468.1 509568 509840 D KEGG: sbo:SBO_3150 hypothetical protein; hypothetical protein 509568..509840 Escherichia coli ATCC 8739 6068363 YP_001723472.1 CDS EcolC_0468 NC_010468.1 509896 510159 R PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_3151 hypothetical protein; hypothetical protein complement(509896..510159) Escherichia coli ATCC 8739 6068367 YP_001723473.1 CDS EcolC_0469 NC_010468.1 510524 510994 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor complement(510524..510994) Escherichia coli ATCC 8739 6068375 YP_001723474.1 CDS EcolC_0470 NC_010468.1 511429 512367 D oxidizes malate to oxaloacetate; malate dehydrogenase 511429..512367 Escherichia coli ATCC 8739 6068378 YP_001723475.1 CDS EcolC_0471 NC_010468.1 512430 513497 R TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: sdy:SDY_3411 protease; serine endoprotease complement(512430..513497) Escherichia coli ATCC 8739 6068387 YP_001723476.1 CDS EcolC_0472 NC_010468.1 513587 514954 R KEGG: sdy:SDY_3410 serine endoprotease; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; serine endoprotease complement(513587..514954) Escherichia coli ATCC 8739 6068402 YP_001723477.1 CDS EcolC_0473 NC_010468.1 515108 515506 R PFAM: protein of unknown function DUF1043; KEGG: sbo:SBO_3156 hypothetical protein; cytochrome d ubiquinol oxidase subunit III complement(515108..515506) Escherichia coli ATCC 8739 6068421 YP_001723478.1 CDS EcolC_0474 NC_010468.1 515700 516827 D PFAM: AFG1-family ATPase; KEGG: sfv:SFV_3259 hypothetical protein; AFG1 family ATPase 515700..516827 Escherichia coli ATCC 8739 6068433 YP_001723479.1 CDS rplM NC_010468.1 517046 517474 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 517046..517474 Escherichia coli ATCC 8739 6068438 YP_001723480.1 CDS rpsI NC_010468.1 517490 517882 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 517490..517882 Escherichia coli ATCC 8739 6068447 YP_001723481.1 CDS sspA NC_010468.1 518277 518915 D transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 518277..518915 Escherichia coli ATCC 8739 6068453 YP_001723482.1 CDS EcolC_0478 NC_010468.1 518921 519418 D PFAM: Stringent starvation protein B; KEGG: sbo:SBO_3161 stringent starvation protein B; ClpXP protease specificity-enhancing factor 518921..519418 Escherichia coli ATCC 8739 6068466 YP_001723483.1 CDS EcolC_0479 NC_010468.1 519461 520828 R YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD complement(519461..520828) Escherichia coli ATCC 8739 6068481 YP_001723484.1 CDS EcolC_0480 NC_010468.1 521208 521999 D Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 521208..521999 Escherichia coli ATCC 8739 6068485 YP_001723485.1 CDS EcolC_0481 NC_010468.1 522121 523014 D catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 522121..523014 Escherichia coli ATCC 8739 6068493 YP_001723486.1 CDS EcolC_0482 NC_010468.1 523123 524613 D TIGRFAM: sialic acid transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3365 sialic acid transporter; putative sialic acid transporter 523123..524613 Escherichia coli ATCC 8739 6068501 YP_001723487.1 CDS EcolC_0483 NC_010468.1 524661 525350 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 524661..525350 Escherichia coli ATCC 8739 6068512 YP_001723488.1 CDS EcolC_0484 NC_010468.1 525347 526222 D catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 525347..526222 Escherichia coli ATCC 8739 6068517 YP_001723489.1 CDS EcolC_0485 NC_010468.1 526219 526683 D PFAM: conserved hypothetical protein; KEGG: sfv:SFV_3246 hypothetical protein; hypothetical protein 526219..526683 Escherichia coli ATCC 8739 6068522 YP_001723490.1 CDS EcolC_0486 NC_010468.1 527081 527560 R PFAM: protein of unknown function DUF1016; KEGG: sdy:SDY_3395 hypothetical protein; hypothetical protein complement(527081..527560) Escherichia coli ATCC 8739 6068529 YP_001723491.1 CDS gltD NC_010468.1 527744 529162 R glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta complement(527744..529162) Escherichia coli ATCC 8739 6068533 YP_001723492.1 CDS gltB NC_010468.1 529175 533743 R catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha complement(529175..533743) Escherichia coli ATCC 8739 6068543 YP_001723493.1 CDS EcolC_0489 NC_010468.1 534277 535239 D KEGG: sbo:SBO_3171 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; putative radical SAM protein 534277..535239 Escherichia coli ATCC 8739 6068549 YP_001723494.1 CDS EcolC_0490 NC_010468.1 535335 537671 D sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 535335..537671 Escherichia coli ATCC 8739 6068562 YP_001723495.1 CDS EcolC_0491 NC_010468.1 537901 538554 D PFAM: ThiJ/PfpI domain protein; KEGG: sfv:SFV_3239 sigma cross-reacting protein 27A (SCRP-27A); amidotransferase 537901..538554 Escherichia coli ATCC 8739 6068566 YP_001723496.1 CDS mtgA NC_010468.1 538551 539279 D glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 538551..539279 Escherichia coli ATCC 8739 6068568 YP_001723497.1 CDS EcolC_0493 NC_010468.1 539276 539908 R KEGG: sfx:S3465 hypothetical protein; hypothetical protein complement(539276..539908) Escherichia coli ATCC 8739 6068576 YP_001723498.1 CDS EcolC_0494 NC_010468.1 540121 540393 R TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: sdy:SDY_3387 phosphocarrier protein HPr-like NPr; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) complement(540121..540393) Escherichia coli ATCC 8739 6068579 YP_001723499.1 CDS EcolC_0495 NC_010468.1 540390 541244 R PFAM: conserved hypothetical protein; KEGG: sbo:SBO_3177 hypothetical protein; hypothetical protein complement(540390..541244) Escherichia coli ATCC 8739 6068586 YP_001723500.1 CDS EcolC_0496 NC_010468.1 541290 541781 R TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sbo:SBO_3178 phosphotransferase system enzyme IIA; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN complement(541290..541781) Escherichia coli ATCC 8739 6068592 YP_001723501.1 CDS EcolC_0497 NC_010468.1 541899 542186 R YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein complement(541899..542186) Escherichia coli ATCC 8739 6068600 YP_001723502.1 CDS EcolC_0498 NC_010468.1 542209 543642 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 complement(542209..543642) Escherichia coli ATCC 8739 6068602 YP_001723503.1 CDS EcolC_0499 NC_010468.1 543690 544415 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_3382 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein YhbG complement(543690..544415) Escherichia coli ATCC 8739 6068605 YP_001723504.1 CDS EcolC_0500 NC_010468.1 544422 544979 R LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA complement(544422..544979) Escherichia coli ATCC 8739 6068611 YP_001723505.1 CDS EcolC_0501 NC_010468.1 544948 545523 R PFAM: protein of unknown function DUF1239; KEGG: sdy:SDY_3380 hypothetical protein; hypothetical protein complement(544948..545523) Escherichia coli ATCC 8739 6068614 YP_001723506.1 CDS EcolC_0502 NC_010468.1 545520 546086 R forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase complement(545520..546086) Escherichia coli ATCC 8739 6068619 YP_001723507.1 CDS EcolC_0503 NC_010468.1 546107 547093 R KEGG: sbo:SBO_3185 putative isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); D-arabinose 5-phosphate isomerase complement(546107..547093) Escherichia coli ATCC 8739 6068624 YP_001723508.1 CDS EcolC_0504 NC_010468.1 547107 548084 R YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter complement(547107..548084) Escherichia coli ATCC 8739 6068626 YP_001723509.1 CDS EcolC_0505 NC_010468.1 548294 549103 D ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF 548294..549103 Escherichia coli ATCC 8739 6068628 YP_001723510.1 CDS EcolC_0506 NC_010468.1 549111 549893 D PFAM: protein of unknown function DUF140; KEGG: sbo:SBO_3188 hypothetical protein; hypothetical protein 549111..549893 Escherichia coli ATCC 8739 6068635 YP_001723511.1 CDS EcolC_0507 NC_010468.1 549898 550449 D PFAM: Mammalian cell entry related domain protein; KEGG: sbo:SBO_3189 hypothetical protein; hypothetical protein 549898..550449 Escherichia coli ATCC 8739 6068641 YP_001723512.1 CDS EcolC_0508 NC_010468.1 550468 551103 D PFAM: toluene tolerance family protein; KEGG: sbo:SBO_3190 hypothetical protein; toluene tolerance family protein 550468..551103 Escherichia coli ATCC 8739 6068646 YP_001723513.1 CDS EcolC_0509 NC_010468.1 551103 551396 D KEGG: sdy:SDY_3372 hypothetical protein; hypothetical protein 551103..551396 Escherichia coli ATCC 8739 6068655 YP_001723514.1 CDS EcolC_0510 NC_010468.1 551556 551810 D PFAM: BolA family protein; KEGG: sdy:SDY_3371 hypothetical protein; BolA family protein 551556..551810 Escherichia coli ATCC 8739 6068659 YP_001723515.1 CDS EcolC_0511 NC_010468.1 551865 553124 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 551865..553124 Escherichia coli ATCC 8739 6068666 YP_001723516.1 CDS EcolC_0512 NC_010468.1 553172 553450 R activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp complement(553172..553450) Escherichia coli ATCC 8739 6068669 YP_001723517.1 CDS EcolC_0513 NC_010468.1 553679 554650 R PFAM: Polyprenyl synthetase; KEGG: sbo:SBO_3195 octaprenyl diphosphate synthase; octaprenyl diphosphate synthase complement(553679..554650) Escherichia coli ATCC 8739 6068675 YP_001723518.1 CDS rplU NC_010468.1 554909 555220 D PFAM: ribosomal protein L21; KEGG: sdy:SDY_3367 50S ribosomal subunit protein L21; 50S ribosomal protein L21 554909..555220 Escherichia coli ATCC 8739 6068676 YP_001723519.1 CDS rpmA NC_010468.1 555241 555498 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 555241..555498 Escherichia coli ATCC 8739 6068678 YP_001723520.1 CDS EcolC_0516 NC_010468.1 555625 556590 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_3198 hypothetical protein; hypothetical protein 555625..556590 Escherichia coli ATCC 8739 6068682 YP_001723521.1 CDS obgE NC_010468.1 556606 557778 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 556606..557778 Escherichia coli ATCC 8739 6068686 YP_001723522.1 CDS EcolC_0518 NC_010468.1 557964 559397 R penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(557964..559397) Escherichia coli ATCC 8739 6068695 YP_001723523.1 CDS greA NC_010468.1 559645 560121 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 559645..560121 Escherichia coli ATCC 8739 6068700 YP_001723524.1 CDS EcolC_0520 NC_010468.1 560277 560570 R RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY complement(560277..560570) Escherichia coli ATCC 8739 6068704 YP_001723525.1 CDS rrmJ NC_010468.1 560696 561325 D Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 560696..561325 Escherichia coli ATCC 8739 6068716 YP_001723526.1 CDS hflB NC_010468.1 561425 563359 D inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 561425..563359 Escherichia coli ATCC 8739 6068720 YP_001723527.1 CDS folP NC_010468.1 563449 564297 D catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 563449..564297 Escherichia coli ATCC 8739 6068728 YP_001723528.1 CDS glmM NC_010468.1 564290 565627 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 564290..565627 Escherichia coli ATCC 8739 6068744 YP_001723529.1 CDS secG NC_010468.1 565855 566187 D TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: ssn:SSON_3323 SecG; preprotein translocase subunit SecG 565855..566187 Escherichia coli ATCC 8739 6064457 YP_001723530.1 CDS EcolC_0526 NC_010468.1 566747 568372 D PFAM: sulfatase; KEGG: sbo:SBO_3209 putative alkaline phosphatase I; sulfatase 566747..568372 Escherichia coli ATCC 8739 6064545 YP_001723531.1 CDS EcolC_0527 NC_010468.1 568380 569723 R catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase complement(568380..569723) Escherichia coli ATCC 8739 6064582 YP_001723532.2 CDS EcolC_0528 NC_010468.1 570354 570806 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 570354..570806 Escherichia coli ATCC 8739 6064616 YP_001723533.1 CDS nusA NC_010468.1 570834 572321 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 570834..572321 Escherichia coli ATCC 8739 6064624 YP_001723534.1 CDS infB NC_010468.1 572346 575018 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 572346..575018 Escherichia coli ATCC 8739 6064626 YP_001723535.1 CDS rbfA NC_010468.1 575182 575583 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 575182..575583 Escherichia coli ATCC 8739 6064639 YP_001723536.1 CDS truB NC_010468.1 575583 576527 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 575583..576527 Escherichia coli ATCC 8739 6064649 YP_001723537.1 CDS rpsO NC_010468.1 576676 576945 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 576676..576945 Escherichia coli ATCC 8739 6064664 YP_001723538.1 CDS EcolC_0534 NC_010468.1 577192 579327 D KEGG: ssn:SSON_3310 polynucleotide phosphorylase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein; polynucleotide phosphorylase/polyadenylase 577192..579327 Escherichia coli ATCC 8739 6064672 YP_001723539.1 CDS EcolC_0535 NC_010468.1 579436 580320 D lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 579436..580320 Escherichia coli ATCC 8739 6064686 YP_001723540.1 CDS EcolC_0536 NC_010468.1 580500 582389 D participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 580500..582389 Escherichia coli ATCC 8739 6064695 YP_001723541.1 CDS EcolC_0537 NC_010468.1 582543 583787 D tryptophan transporter of high affinity; tryptophan permease 582543..583787 Escherichia coli ATCC 8739 6064714 YP_001723542.1 CDS EcolC_0538 NC_010468.1 583905 584912 R PFAM: luciferase family protein; KEGG: sbo:SBO_3222 putative enzyme; hypothetical protein complement(583905..584912) Escherichia coli ATCC 8739 6064723 YP_001723543.1 CDS EcolC_0539 NC_010468.1 584993 585871 R PFAM: peptidase U32; KEGG: sdy:SDY_3338 hypothetical protein; peptidase U32 complement(584993..585871) Escherichia coli ATCC 8739 6064742 YP_001723544.1 CDS EcolC_0540 NC_010468.1 585880 586875 R PFAM: peptidase U32; KEGG: ssn:SSON_3304 putative collagenase; peptidase U32 complement(585880..586875) Escherichia coli ATCC 8739 6064736 YP_001723545.1 CDS EcolC_0541 NC_010468.1 587084 587608 D PFAM: Sterol-binding domain protein; KEGG: sdy:SDY_3336 hypothetical protein; sterol-binding domain-containing protein 587084..587608 Escherichia coli ATCC 8739 6064750 YP_001723546.1 CDS EcolC_0542 NC_010468.1 587602 588105 D PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_3335 hypothetical protein; N-acetyltransferase GCN5 587602..588105 Escherichia coli ATCC 8739 6064776 YP_001723547.2 CDS EcolC_0543 NC_010468.1 588092 588394 R PFAM: Excinuclease ABC C subunit domain protein; KEGG: sfv:SFV_3185 hypothetical protein; GIY-YIG nuclease superfamily protein complement(588092..588394) Escherichia coli ATCC 8739 6064799 YP_001723548.1 CDS EcolC_0544 NC_010468.1 588445 588888 D KEGG: sfv:SFV_3184 hypothetical protein; hypothetical protein 588445..588888 Escherichia coli ATCC 8739 6064786 YP_001723549.1 CDS EcolC_0545 NC_010468.1 588868 589386 R TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: sdy:SDY_3332 hypothetical protein; PfpI family intracellular peptidase complement(588868..589386) Escherichia coli ATCC 8739 6064815 YP_001723550.1 CDS EcolC_0546 NC_010468.1 589514 590149 D PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_3230 hypothetical protein; NAD-dependent epimerase/dehydratase 589514..590149 Escherichia coli ATCC 8739 6064832 YP_001723551.1 CDS EcolC_0547 NC_010468.1 590222 591262 D PFAM: permease; KEGG: ssn:SSON_3297 hypothetical protein; permease 590222..591262 Escherichia coli ATCC 8739 6064855 YP_001723552.1 CDS EcolC_0548 NC_010468.1 591376 591951 R PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: sdy:SDY_3329 putative periplasmic protein; hypothetical protein complement(591376..591951) Escherichia coli ATCC 8739 6064852 YP_001723553.1 CDS EcolC_0549 NC_010468.1 591961 592551 R Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA complement(591961..592551) Escherichia coli ATCC 8739 6064895 YP_001723554.1 CDS EcolC_0550 NC_010468.1 592571 592966 R PFAM: protein of unknown function UPF0102; KEGG: ssn:SSON_3294 hypothetical protein; hypothetical protein complement(592571..592966) Escherichia coli ATCC 8739 6064934 YP_001723555.1 CDS EcolC_0551 NC_010468.1 592924 594960 R PFAM: LppC family lipoprotein; KEGG: ssn:SSON_3293 putative glycosylase; LppC family lipoprotein complement(592924..594960) Escherichia coli ATCC 8739 6064908 YP_001723556.1 CDS EcolC_0552 NC_010468.1 595024 595884 D PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdy:SDY_3325 hypothetical protein; uroporphyrin-III C/tetrapyrrole methyltransferase 595024..595884 Escherichia coli ATCC 8739 6064953 YP_001723557.1 CDS EcolC_0553 NC_010468.1 595927 597018 R KEGG: sfv:SFV_3175 putative fimbrial protein; putative fimbrial protein complement(595927..597018) Escherichia coli ATCC 8739 6064969 YP_001723558.1 CDS EcolC_0554 NC_010468.1 597029 599545 R PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ssn:SSON_3289 putative outer membrane protein; fimbrial biogenesis outer membrane usher protein complement(597029..599545) Escherichia coli ATCC 8739 6064985 YP_001723559.1 CDS EcolC_0555 NC_010468.1 599575 600270 R PFAM: pili assembly chaperone; KEGG: sfv:SFV_3171 putative chaperone; pili assembly chaperone complement(599575..600270) Escherichia coli ATCC 8739 6065003 YP_001723560.1 CDS EcolC_0556 NC_010468.1 600350 600934 R PFAM: Fimbrial protein; KEGG: esa:ESA_02345 hypothetical protein; fimbrial protein complement(600350..600934) Escherichia coli ATCC 8739 6065063 YP_001723561.1 CDS EcolC_0557 NC_010468.1 601335 602036 R PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfx:S3393 putative galactosamine-6-phosphate isomerase; galactosamine-6-phosphate isomerase complement(601335..602036) Escherichia coli ATCC 8739 6065123 YP_001723562.1 CDS EcolC_0558 NC_010468.1 602091 602882 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID complement(602091..602882) Escherichia coli ATCC 8739 6065098 YP_001723563.1 CDS EcolC_0559 NC_010468.1 602872 603675 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(602872..603675) Escherichia coli ATCC 8739 6065140 YP_001723564.1 CDS EcolC_0560 NC_010468.1 603714 604190 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(603714..604190) Escherichia coli ATCC 8739 6065179 YP_001723565.1 CDS kbaY NC_010468.1 604357 605217 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(604357..605217) Escherichia coli ATCC 8739 6064391 YP_001723566.1 CDS EcolC_0562 NC_010468.1 605230 606384 R TIGRFAM: sugar isomerase, AgaS family; PFAM: sugar isomerase (SIS); KEGG: cko:CKO_04536 hypothetical protein; AgaS family sugar isomerase complement(605230..606384) Escherichia coli ATCC 8739 6064387 YP_001723567.1 CDS EcolC_0563 NC_010468.1 606735 607868 R KEGG: cko:CKO_04535 hypothetical protein; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; N-acetylglucosamine-6-phosphate deacetylase complement(606735..607868) Escherichia coli ATCC 8739 6064426 YP_001723568.1 CDS EcolC_0564 NC_010468.1 607865 608299 R PFAM: PTS system fructose subfamily IIA component; KEGG: sfx:S3386 putative transport enzyme subunit; PTS system fructose subfamily transporter subunit IIA complement(607865..608299) Escherichia coli ATCC 8739 6064819 YP_001723569.1 CDS EcolC_0565 NC_010468.1 608317 609195 R PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: cko:CKO_04533 hypothetical protein; PTS system mannose/fructose/sorbose family transporter subunit IID complement(608317..609195) Escherichia coli ATCC 8739 6067539 YP_001723570.1 CDS EcolC_0566 NC_010468.1 609185 609964 R PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sfx:S3384 N-acetylgalactosameine-specific IIC component 2; PTS system sorbose-specific transporter subunit IIC complement(609185..609964) Escherichia coli ATCC 8739 6067260 YP_001723571.1 CDS EcolC_0567 NC_010468.1 609975 610448 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(609975..610448) Escherichia coli ATCC 8739 6065024 YP_001723572.1 CDS EcolC_0568 NC_010468.1 610471 611751 R KEGG: sfx:S3382 putative tagatose 6-phosphate kinase 2; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; D-tagatose-bisphosphate aldolase non-catalytic subunit complement(610471..611751) Escherichia coli ATCC 8739 6067122 YP_001723573.1 CDS EcolC_0569 NC_010468.1 612000 612809 D transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 612000..612809 Escherichia coli ATCC 8739 6066424 YP_001723574.1 CDS EcolC_0570 NC_010468.1 612864 613328 R KEGG: ssn:SSON_3287 hypothetical protein; hypothetical protein complement(612864..613328) Escherichia coli ATCC 8739 6066631 YP_001723575.1 CDS EcolC_0571 NC_010468.1 613328 613663 R SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF complement(613328..613663) Escherichia coli ATCC 8739 6064966 YP_001723576.1 CDS EcolC_0572 NC_010468.1 613812 615383 R KEGG: sfx:S3380 putative hydrolase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; galactarate dehydratase complement(613812..615383) Escherichia coli ATCC 8739 6066119 YP_001723577.1 CDS EcolC_0573 NC_010468.1 615758 617092 D TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S3379 putative transport protein; d-galactonate transporter 615758..617092 Escherichia coli ATCC 8739 6065847 YP_001723578.1 CDS EcolC_0574 NC_010468.1 617108 617878 D cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 617108..617878 Escherichia coli ATCC 8739 6067595 YP_001723579.1 CDS garR NC_010468.1 617908 618798 D catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 617908..618798 Escherichia coli ATCC 8739 6064798 YP_001723580.1 CDS EcolC_0576 NC_010468.1 618895 620040 D PFAM: glycerate kinase; KEGG: sbo:SBO_2989 hypothetical protein; glycerate kinase 618895..620040 Escherichia coli ATCC 8739 6065454 YP_001723581.1 CDS EcolC_0578 NC_010468.1 622167 622706 R KEGG: sfv:SFV_3161 hypothetical protein; hypothetical protein complement(622167..622706) Escherichia coli ATCC 8739 6065039 YP_001723582.1 CDS EcolC_0579 NC_010468.1 622962 623306 R participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR complement(622962..623306) Escherichia coli ATCC 8739 6066773 YP_001723583.1 CDS EcolC_0580 NC_010468.1 623495 624433 D regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 623495..624433 Escherichia coli ATCC 8739 6064915 YP_001723584.1 CDS EcolC_0581 NC_010468.1 624532 625521 D catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 624532..625521 Escherichia coli ATCC 8739 6066772 YP_001723585.1 CDS EcolC_0582 NC_010468.1 625543 626874 D involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 625543..626874 Escherichia coli ATCC 8739 6066130 YP_001723586.1 CDS EcolC_0583 NC_010468.1 626900 628108 D catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 626900..628108 Escherichia coli ATCC 8739 6065190 YP_001723587.1 CDS EcolC_0584 NC_010468.1 628142 630436 D KEGG: ssn:SSON_3271 probable formate acetyltransferase 3; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; formate acetyltransferase 628142..630436 Escherichia coli ATCC 8739 6065942 YP_001723588.1 CDS EcolC_0585 NC_010468.1 630450 630839 D TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sbo:SBO_2978 hypothetical protein; hypothetical protein 630450..630839 Escherichia coli ATCC 8739 6066148 YP_001723589.1 CDS EcolC_0586 NC_010468.1 630911 632275 D KEGG: sfv:SFV_3153 putative L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 630911..632275 Escherichia coli ATCC 8739 6065775 YP_001723590.1 CDS EcolC_0587 NC_010468.1 632550 633881 D TIGRFAM: serine transporter; KEGG: ssn:SSON_3268 putative transport system permease protein; serine transporter 632550..633881 Escherichia coli ATCC 8739 6066146 YP_001723591.1 CDS EcolC_0588 NC_010468.1 633909 635219 D PFAM: protein of unknown function DUF1063; KEGG: sbo:SBO_2975 hypothetical protein; hypothetical protein 633909..635219 Escherichia coli ATCC 8739 6066210 YP_001723592.1 CDS EcolC_0589 NC_010468.1 635353 635517 R KEGG: sdy:SDY_3299 hypothetical protein; hypothetical protein complement(635353..635517) Escherichia coli ATCC 8739 6066290 YP_001723593.1 CDS EcolC_0590 NC_010468.1 635540 636241 R PFAM: Pirin domain protein; KEGG: sbo:SBO_2973 hypothetical protein; pirin domain-containing protein complement(635540..636241) Escherichia coli ATCC 8739 6066413 YP_001723594.1 CDS EcolC_0591 NC_010468.1 636346 637242 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2972 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 636346..637242 Escherichia coli ATCC 8739 6064476 YP_001723595.1 CDS EcolC_0592 NC_010468.1 637293 637649 R PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_3263 putative cytochrome; hypothetical protein complement(637293..637649) Escherichia coli ATCC 8739 6065814 YP_001723596.1 CDS EcolC_0593 NC_010468.1 637890 638255 R PFAM: protein of unknown function DUF805; KEGG: sbo:SBO_2970 putative cytochrome; hypothetical protein complement(637890..638255) Escherichia coli ATCC 8739 6064700 YP_001723597.1 CDS EcolC_0594 NC_010468.1 638548 639534 R KEGG: sdy:SDY_3291 putative transferase; putative transferase complement(638548..639534) Escherichia coli ATCC 8739 6064661 YP_001723598.1 CDS EcolC_0595 NC_010468.1 639604 639996 R PFAM: DoxX family protein; KEGG: sdy:SDY_3290 hypothetical protein; DoxX family protein complement(639604..639996) Escherichia coli ATCC 8739 6065270 YP_001723599.1 CDS EcolC_0596 NC_010468.1 640182 640481 R KEGG: sbo:SBO_2967 hypothetical protein; hypothetical protein complement(640182..640481) Escherichia coli ATCC 8739 6065272 YP_001723600.1 CDS EcolC_0597 NC_010468.1 640471 640875 R KEGG: sbo:SBO_2966 hypothetical protein; hypothetical protein complement(640471..640875) Escherichia coli ATCC 8739 6065165 YP_001723601.1 CDS EcolC_0598 NC_010468.1 640878 641183 R PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_3285 hypothetical protein; hypothetical protein complement(640878..641183) Escherichia coli ATCC 8739 6065769 YP_001723602.1 CDS EcolC_0599 NC_010468.1 641221 641589 R PFAM: protein of unknown function DUF1090; KEGG: sbo:SBO_2964 hypothetical protein; hypothetical protein complement(641221..641589) Escherichia coli ATCC 8739 6066196 YP_001723603.1 CDS EcolC_0600 NC_010468.1 641736 642119 R KEGG: sdy:SDY_3283 hypothetical protein; hypothetical protein complement(641736..642119) Escherichia coli ATCC 8739 6065318 YP_001723604.1 CDS EcolC_0601 NC_010468.1 642123 642785 R PFAM: SNARE associated Golgi protein; KEGG: sdy:SDY_3282 hypothetical protein; hypothetical protein complement(642123..642785) Escherichia coli ATCC 8739 6065525 YP_001723605.1 CDS EcolC_0602 NC_010468.1 643130 643906 R regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR complement(643130..643906) Escherichia coli ATCC 8739 6065487 YP_001723606.1 CDS EcolC_0603 NC_010468.1 644202 644918 D KEGG: ssn:SSON_3252 putative fimbrial protein; hypothetical protein 644202..644918 Escherichia coli ATCC 8739 6067179 YP_001723607.1 CDS EcolC_0604 NC_010468.1 644948 645448 D PFAM: CS1 type fimbrial major subunit; KEGG: sbo:SBO_2959 putative fimbrial subunit; CS1 type fimbrial major subunit 644948..645448 Escherichia coli ATCC 8739 6064961 YP_001723608.1 CDS EcolC_0605 NC_010468.1 645539 648223 D KEGG: ssn:SSON_3248 outer membrane fimbrial user protein; outer membrane fimbrial user protein 645539..648223 Escherichia coli ATCC 8739 6067677 YP_001723609.1 CDS EcolC_0606 NC_010468.1 648220 649308 D PFAM: CblD family pilus biogenesis initiator protein; KEGG: ssn:SSON_3247 putative minor pilin and initiator; CblD family pilus biogenesis initiator protein 648220..649308 Escherichia coli ATCC 8739 6065337 YP_001723610.1 CDS EcolC_0607 NC_010468.1 649396 650694 R TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3134 transport of hexuronates; d-galactonate transporter complement(649396..650694) Escherichia coli ATCC 8739 6065014 YP_001723611.1 CDS EcolC_0608 NC_010468.1 651177 652589 D catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 651177..652589 Escherichia coli ATCC 8739 6065566 YP_001723612.1 CDS EcolC_0609 NC_010468.1 652604 654091 D PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: sdy:SDY_3276 altronate hydrolase; altronate dehydratase 652604..654091 Escherichia coli ATCC 8739 6066450 YP_001723613.1 CDS EcolC_0610 NC_010468.1 654174 654725 D KEGG: ssn:SSON_3243 hypothetical protein; hypothetical protein 654174..654725 Escherichia coli ATCC 8739 6066514 YP_001723614.1 CDS EcolC_0611 NC_010468.1 654730 655974 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(654730..655974) Escherichia coli ATCC 8739 6065978 YP_001723615.1 CDS EcolC_0612 NC_010468.1 656373 657338 R PFAM: Integral membrane protein TerC; KEGG: ssn:SSON_3117 putative transport protein; integral membrane protein TerC complement(656373..657338) Escherichia coli ATCC 8739 6066829 YP_001723616.1 CDS EcolC_0613 NC_010468.1 657621 658607 R PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sfv:SFV_3128 hypothetical protein; oxidoreductase domain-containing protein complement(657621..658607) Escherichia coli ATCC 8739 6066085 YP_001723617.1 CDS EcolC_0614 NC_010468.1 658686 659369 R PFAM: protein of unknown function DUF218; KEGG: sbo:SBO_2947 hypothetical protein; hypothetical protein complement(658686..659369) Escherichia coli ATCC 8739 6067752 YP_001723618.1 CDS EcolC_0615 NC_010468.1 659446 659949 R PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein; hypothetical protein complement(659446..659949) Escherichia coli ATCC 8739 6066858 YP_001723619.1 CDS EcolC_0616 NC_010468.1 660034 661170 D PFAM: methyltransferase small; Methyltransferase type 12; KEGG: sdy:SDY_3267 putative enzyme; rRNA (guanine-N(2)-)-methyltransferase 660034..661170 Escherichia coli ATCC 8739 6067315 YP_001723620.1 CDS EcolC_0617 NC_010468.1 661454 661768 D KEGG: ssn:SSON_3122 hypothetical protein; hypothetical protein 661454..661768 Escherichia coli ATCC 8739 6066143 YP_001723621.1 CDS EcolC_0618 NC_010468.1 661765 662181 D PFAM: helix-turn-helix domain protein; KEGG: sfv:SFV_3123 hypothetical protein; helix-turn-helix domain-containing protein 661765..662181 Escherichia coli ATCC 8739 6065310 YP_001723622.1 CDS EcolC_0619 NC_010468.1 662226 664244 R PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_3124 putative NADPH dehydrogenase; NADH:flavin oxidoreductase complement(662226..664244) Escherichia coli ATCC 8739 6064806 YP_001723623.1 CDS EcolC_0620 NC_010468.1 664670 667021 R KEGG: sfl:SF3120 putative isomerase; putative glycosyl hydrolase complement(664670..667021) Escherichia coli ATCC 8739 6064679 YP_001723624.1 CDS EcolC_0621 NC_010468.1 667038 668108 R KEGG: ssn:SSON_3126 hypothetical protein; hypothetical protein complement(667038..668108) Escherichia coli ATCC 8739 6066855 YP_001723625.1 CDS EcolC_0622 NC_010468.1 668242 669675 R PFAM: amino acid permease-associated region; KEGG: sbo:SBO_2937 putative oxidoreductase; amino acid permease-associated protein complement(668242..669675) Escherichia coli ATCC 8739 6066512 YP_001723626.1 CDS ebgC NC_010468.1 669738 670187 R in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta complement(669738..670187) Escherichia coli ATCC 8739 6065534 YP_001723627.1 CDS ebgA NC_010468.1 670184 673276 R in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha complement(670184..673276) Escherichia coli ATCC 8739 6064632 YP_001723628.1 CDS EcolC_0625 NC_010468.1 673460 674443 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sdy:SDY_3259 regulator of ebg operon; DNA-binding transcriptional repressor EbgR complement(673460..674443) Escherichia coli ATCC 8739 6065424 YP_001723629.1 CDS EcolC_0626 NC_010468.1 674662 674994 D PFAM: t-RNA-binding domain protein; KEGG: sbo:SBO_2933 putative tRNA synthetase; hypothetical protein 674662..674994 Escherichia coli ATCC 8739 6066562 YP_001723630.1 CDS EcolC_0627 NC_010468.1 675036 676325 R catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase complement(675036..676325) Escherichia coli ATCC 8739 6066715 YP_001723631.1 CDS EcolC_0628 NC_010468.1 676833 678353 D KEGG: ssn:SSON_3210 aerotaxis sensor receptor, flavoprotein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor 676833..678353 Escherichia coli ATCC 8739 6065695 YP_001723632.1 CDS EcolC_0629 NC_010468.1 678507 679130 R PFAM: transcriptional regulator PadR family protein; KEGG: sbo:SBO_2930 hypothetical protein; PadR-like family transcriptional regulator complement(678507..679130) Escherichia coli ATCC 8739 6067083 YP_001723633.1 CDS EcolC_0630 NC_010468.1 679418 680182 D PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: sbo:SBO_2929 hypothetical protein; FAD-binding 9 siderophore-interacting domain-containing protein 679418..680182 Escherichia coli ATCC 8739 6066045 YP_001723634.1 CDS EcolC_0631 NC_010468.1 680436 680942 D PFAM: Uracil-DNA glycosylase superfamily; KEGG: sbo:SBO_2927 hypothetical protein; G/U mismatch-specific DNA glycosylase 680436..680942 Escherichia coli ATCC 8739 6065957 YP_001723635.1 CDS EcolC_0632 NC_010468.1 681021 682862 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(681021..682862) Escherichia coli ATCC 8739 6066445 YP_001723636.1 CDS dnaG NC_010468.1 683057 684802 R synthesizes RNA primers at the replication forks; DNA primase complement(683057..684802) Escherichia coli ATCC 8739 6066446 YP_001723637.1 CDS rpsU NC_010468.1 684913 685128 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(684913..685128) Escherichia coli ATCC 8739 6066911 YP_001723638.1 CDS EcolC_0635 NC_010468.1 685365 686378 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 685365..686378 Escherichia coli ATCC 8739 6065430 YP_001723639.1 CDS EcolC_0636 NC_010468.1 686421 687884 R TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: sfv:SFV_3103 hypothetical protein; anion transporter complement(686421..687884) Escherichia coli ATCC 8739 6064613 YP_001723640.1 CDS EcolC_0637 NC_010468.1 687932 688537 R Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta complement(687932..688537) Escherichia coli ATCC 8739 6064610 YP_001723641.1 CDS EcolC_0638 NC_010468.1 688534 689445 R Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha complement(688534..689445) Escherichia coli ATCC 8739 6066378 YP_001723642.1 CDS EcolC_0639 NC_010468.1 689652 690584 D activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 689652..690584 Escherichia coli ATCC 8739 6065773 YP_001723643.1 CDS EcolC_0640 NC_010468.1 690597 691214 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY complement(690597..691214) Escherichia coli ATCC 8739 6066272 YP_001723644.1 CDS folB NC_010468.1 691319 691687 D catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 691319..691687 Escherichia coli ATCC 8739 6065330 YP_001723645.1 CDS EcolC_0642 NC_010468.1 691777 692598 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 691777..692598 Escherichia coli ATCC 8739 6065744 YP_001723646.1 CDS cca NC_010468.1 692779 694017 R catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase complement(692779..694017) Escherichia coli ATCC 8739 6067127 YP_001723647.1 CDS EcolC_0644 NC_010468.1 694081 694701 R SMART: SH3 domain protein; KEGG: ssn:SSON_3192 hypothetical protein; putative signal transduction protein complement(694081..694701) Escherichia coli ATCC 8739 6065678 YP_001723648.1 CDS EcolC_0645 NC_010468.1 694943 696244 D PFAM: CHAD domain containing protein; adenylate cyclase; KEGG: sdy:SDY_3237 hypothetical protein; adenylate cyclase 694943..696244 Escherichia coli ATCC 8739 6065504 YP_001723649.1 CDS EcolC_0646 NC_010468.1 696267 699107 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 696267..699107 Escherichia coli ATCC 8739 6066688 YP_001723650.1 CDS EcolC_0647 NC_010468.1 699155 700588 D catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 699155..700588 Escherichia coli ATCC 8739 6066685 YP_001723651.1 CDS EcolC_0648 NC_010468.1 701381 703042 R PFAM: band 7 protein; KEGG: ssn:SSON_3188 hypothetical protein; hypothetical protein complement(701381..703042) Escherichia coli ATCC 8739 6065681 YP_001723652.1 CDS EcolC_0649 NC_010468.1 703069 703698 R PFAM: protein of unknown function DUF1449; KEGG: ssn:SSON_3187 putative oxidoreductase; hypothetical protein complement(703069..703698) Escherichia coli ATCC 8739 6067076 YP_001723653.1 CDS EcolC_0650 NC_010468.1 703967 704167 D Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 703967..704167 Escherichia coli ATCC 8739 6065111 YP_001723654.1 CDS EcolC_0651 NC_010468.1 704210 705241 R KEGG: ssn:SSON_3184 hypothetical protein; hypothetical protein complement(704210..705241) Escherichia coli ATCC 8739 6064822 YP_001723655.1 CDS EcolC_0652 NC_010468.1 705276 706025 R PFAM: pili assembly chaperone; KEGG: ssn:SSON_3183 hypothetical protein; pili assembly chaperone complement(705276..706025) Escherichia coli ATCC 8739 6066235 YP_001723656.1 CDS EcolC_0653 NC_010468.1 706047 708545 R PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB3895 outer membrane fimbrial usher porin; fimbrial biogenesis outer membrane usher protein complement(706047..708545) Escherichia coli ATCC 8739 6064803 YP_001723657.1 CDS EcolC_0654 NC_010468.1 708605 709156 R PFAM: Fimbrial protein; KEGG: ssn:SSON_3180 putative fimbrial-like protein; putative fimbrial protein complement(708605..709156) Escherichia coli ATCC 8739 6066382 YP_001723658.1 CDS EcolC_0655 NC_010468.1 709440 709730 R PFAM: protein of unknown function DUF526; KEGG: sfv:SFV_3086 hypothetical protein; hypothetical protein complement(709440..709730) Escherichia coli ATCC 8739 6066066 YP_001723659.1 CDS ribB NC_010468.1 710104 710757 D DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 710104..710757 Escherichia coli ATCC 8739 6066613 YP_001723660.1 CDS EcolC_0657 NC_010468.1 711019 711189 D KEGG: cko:CKO_04433 hypothetical protein; hypothetical protein 711019..711189 Escherichia coli ATCC 8739 6067100 YP_001723661.1 CDS EcolC_0658 NC_010468.1 711247 712020 R PFAM: zinc/iron permease; KEGG: ssn:SSON_3177 hypothetical protein; zinc transporter ZupT complement(711247..712020) Escherichia coli ATCC 8739 6067515 YP_001723662.1 CDS EcolC_0659 NC_010468.1 712136 712951 D seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 712136..712951 Escherichia coli ATCC 8739 6067563 YP_001723663.1 CDS EcolC_0660 NC_010468.1 712989 714149 R PFAM: glutathionylspermidine synthase; KEGG: sfv:SFV_3082 putative synthetase/amidase; glutathionylspermidine synthase complement(712989..714149) Escherichia coli ATCC 8739 6065516 YP_001723664.1 CDS EcolC_0661 NC_010468.1 714155 714826 R KEGG: ssn:SSON_3174 hypothetical protein; hypothetical protein complement(714155..714826) Escherichia coli ATCC 8739 6065168 YP_001723665.1 CDS tolC NC_010468.1 714974 716455 R trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein complement(714974..716455) Escherichia coli ATCC 8739 6065508 YP_001723666.1 CDS nudF NC_010468.1 716660 717289 D ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 716660..717289 Escherichia coli ATCC 8739 6066990 YP_001723667.1 CDS EcolC_0664 NC_010468.1 717290 717712 D PFAM: protein of unknown function DUF1249; KEGG: ssn:SSON_3171 putative enzyme; hypothetical protein 717290..717712 Escherichia coli ATCC 8739 6066331 YP_001723668.1 CDS EcolC_0665 NC_010468.1 717737 718561 D PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: sdy:SDY_3208 regulator of LacZ; cyclic 3',5'-adenosine monophosphate phosphodiesterase 717737..718561 Escherichia coli ATCC 8739 6066254 YP_001723669.1 CDS EcolC_0666 NC_010468.1 718561 719142 D Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 718561..719142 Escherichia coli ATCC 8739 6065076 YP_001723670.1 CDS EcolC_0667 NC_010468.1 719171 721063 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 719171..721063 Escherichia coli ATCC 8739 6066334 YP_001723671.1 CDS EcolC_0668 NC_010468.1 721111 721425 R PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sbo:SBO_2887 hypothetical protein; antibiotic biosynthesis monooxygenase complement(721111..721425) Escherichia coli ATCC 8739 6067291 YP_001723672.1 CDS EcolC_0669 NC_010468.1 721456 722037 R PFAM: NAD(P)H dehydrogenase (quinone); KEGG: sbo:SBO_2886 modulator of drug activity B; NAD(P)H dehydrogenase (quinone) complement(721456..722037) Escherichia coli ATCC 8739 6065951 YP_001723673.1 CDS EcolC_0670 NC_010468.1 722356 722688 D KEGG: sfx:S3272 hypothetical protein; hypothetical protein 722356..722688 Escherichia coli ATCC 8739 6067668 YP_001723674.1 CDS EcolC_0671 NC_010468.1 722734 724083 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_3165 quorum sensing regulator C; sensor protein QseC complement(722734..724083) Escherichia coli ATCC 8739 6066011 YP_001723675.1 CDS EcolC_0672 NC_010468.1 724080 724739 R response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB complement(724080..724739) Escherichia coli ATCC 8739 6064844 YP_001723676.1 CDS EcolC_0673 NC_010468.1 724891 725283 D PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3215 hypothetical protein; hypothetical protein 724891..725283 Escherichia coli ATCC 8739 6064847 YP_001723677.1 CDS EcolC_0674 NC_010468.1 725336 725818 D PFAM: transcription activator effector binding; KEGG: ssn:SSON_3162 hypothetical protein; transcription activator effector binding 725336..725818 Escherichia coli ATCC 8739 6066538 YP_001723678.1 CDS EcolC_0675 NC_010468.1 726023 726319 D KEGG: yps:YPTB3124 hypothetical protein; hypothetical protein 726023..726319 Escherichia coli ATCC 8739 6065665 YP_001723679.1 CDS EcolC_0676 NC_010468.1 726321 726716 D SMART: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_0889 putative transcriptional regulator; XRE family transcriptional regulator 726321..726716 Escherichia coli ATCC 8739 6066535 YP_001723680.1 CDS EcolC_0677 NC_010468.1 726849 728456 D YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein 726849..728456 Escherichia coli ATCC 8739 6065662 YP_001723681.1 CDS EcolC_0678 NC_010468.1 728594 730852 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 728594..730852 Escherichia coli ATCC 8739 6065587 YP_001723682.1 CDS EcolC_0679 NC_010468.1 731086 731823 D KEGG: sbo:SBO_2880 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 731086..731823 Escherichia coli ATCC 8739 6067221 YP_001723683.1 CDS EcolC_0680 NC_010468.1 731898 733310 D PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: sfv:SFV_3066 suppressor of FtsI; repressor protein for FtsI 731898..733310 Escherichia coli ATCC 8739 6067184 YP_001723684.1 CDS EcolC_0681 NC_010468.1 733421 735640 D PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sbo:SBO_2878 Fe-S oxidoreductase; hypothetical protein 733421..735640 Escherichia coli ATCC 8739 6067468 YP_001723685.1 CDS EcolC_0682 NC_010468.1 735683 735940 R KEGG: sbo:SBO_3008 hypothetical protein; putative outer membrane lipoprotein complement(735683..735940) Escherichia coli ATCC 8739 6066460 YP_001723686.1 CDS EcolC_0683 NC_010468.1 735991 736917 R KEGG: sbo:SBO_3007 hypothetical protein; hypothetical protein complement(735991..736917) Escherichia coli ATCC 8739 6065593 YP_001723687.1 CDS dkgA NC_010468.1 737117 737944 R methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A complement(737117..737944) Escherichia coli ATCC 8739 6066814 YP_001723688.1 CDS EcolC_0685 NC_010468.1 738049 739212 R PFAM: iron-containing alcohol dehydrogenase; KEGG: sfv:SFV_3060 putative oxidoreductase; iron-containing alcohol dehydrogenase complement(738049..739212) Escherichia coli ATCC 8739 6064684 YP_001723689.1 CDS EcolC_0686 NC_010468.1 739349 740305 D PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: sbo:SBO_3005 putative AraC-type regulatory protein; AraC family transcriptional regulator 739349..740305 Escherichia coli ATCC 8739 6066680 YP_001723690.1 CDS EcolC_0687 NC_010468.1 740345 741004 R PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_3152 hypothetical protein; hypothetical protein complement(740345..741004) Escherichia coli ATCC 8739 6066805 YP_001723691.1 CDS EcolC_0688 NC_010468.1 741144 742331 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(741144..742331) Escherichia coli ATCC 8739 6065155 YP_001723692.1 CDS EcolC_0689 NC_010468.1 742583 743317 D membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 742583..743317 Escherichia coli ATCC 8739 6066459 YP_001723693.1 CDS EcolC_0690 NC_010468.1 743324 743749 D membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 743324..743749 Escherichia coli ATCC 8739 6066470 YP_001723694.1 CDS EcolC_0691 NC_010468.1 744021 744905 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbo:SBO_2997 putative oxidoreductase; oxidoreductase complement(744021..744905) Escherichia coli ATCC 8739 6065217 YP_001723695.1 CDS EcolC_0692 NC_010468.1 745096 745590 D PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2996 hypothetical protein; hypothetical protein 745096..745590 Escherichia coli ATCC 8739 6066339 YP_001723696.1 CDS EcolC_0693 NC_010468.1 745630 746670 R PFAM: aldo/keto reductase; KEGG: sfv:SFV_3053 putative reductase; aldo-keto reductase complement(745630..746670) Escherichia coli ATCC 8739 6065625 YP_001723697.1 CDS EcolC_0695 NC_010468.1 747831 748118 D KEGG: sdy:SDY_3075 hypothetical protein; hypothetical protein 747831..748118 Escherichia coli ATCC 8739 6064682 YP_001723698.1 CDS EcolC_0696 NC_010468.1 748307 749425 D involved in hydrogen uptake; hydrogenase 2 small subunit 748307..749425 Escherichia coli ATCC 8739 6065128 YP_001723699.1 CDS EcolC_0697 NC_010468.1 749428 750414 D Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 749428..750414 Escherichia coli ATCC 8739 6065323 YP_001723700.1 CDS EcolC_0698 NC_010468.1 750404 751582 D HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 750404..751582 Escherichia coli ATCC 8739 6065345 YP_001723701.1 CDS EcolC_0699 NC_010468.1 751579 753282 D involved in hydrogen uptake; hydrogenase 2 large subunit 751579..753282 Escherichia coli ATCC 8739 6065733 YP_001723702.1 CDS hybD NC_010468.1 753282 753776 D protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 753282..753776 Escherichia coli ATCC 8739 6066456 YP_001723703.1 CDS EcolC_0701 NC_010468.1 753769 754257 D KEGG: sbo:SBO_2871 HybE; hydrogenase 2-specific chaperone 753769..754257 Escherichia coli ATCC 8739 6067105 YP_001723704.1 CDS EcolC_0702 NC_010468.1 754250 754591 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 754250..754591 Escherichia coli ATCC 8739 6066600 YP_001723705.1 CDS EcolC_0703 NC_010468.1 754604 754852 D TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: sdy:SDY_3083 hydrogenase-2 operon protein; hydrogenase 2 accessory protein HypG 754604..754852 Escherichia coli ATCC 8739 6066575 YP_001723706.1 CDS EcolC_0704 NC_010468.1 754975 755841 R YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU complement(754975..755841) Escherichia coli ATCC 8739 6066681 YP_001723707.1 CDS EcolC_0705 NC_010468.1 756046 757905 D catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 756046..757905 Escherichia coli ATCC 8739 6066727 YP_001723708.1 CDS EcolC_0706 NC_010468.1 758197 759696 D PFAM: phosphate transporter; KEGG: ssn:SSON_3132 low-affinity phosphate transport; phosphate transporter 758197..759696 Escherichia coli ATCC 8739 6065079 YP_001723709.1 CDS EcolC_0707 NC_010468.1 759745 760437 R KEGG: sfx:S3234 hypothetical protein; hypothetical protein complement(759745..760437) Escherichia coli ATCC 8739 6066660 YP_001723710.1 CDS EcolC_0708 NC_010468.1 760626 761324 D KEGG: ssn:SSON_3219 hypothetical protein; hypothetical protein 760626..761324 Escherichia coli ATCC 8739 6065878 YP_001723711.1 CDS EcolC_0709 NC_010468.1 761356 762114 D KEGG: ssn:SSON_3220 hypothetical protein; hypothetical protein 761356..762114 Escherichia coli ATCC 8739 6066476 YP_001723712.1 CDS EcolC_0710 NC_010468.1 762160 763509 D PFAM: polysaccharide biosynthesis protein; KEGG: sfx:S3231 hypothetical protein; polysaccharide biosynthesis protein 762160..763509 Escherichia coli ATCC 8739 6065882 YP_001723713.1 CDS EcolC_0711 NC_010468.1 763509 764333 D KEGG: sfx:S3230 hypothetical protein; hypothetical protein 763509..764333 Escherichia coli ATCC 8739 6065989 YP_001723714.1 CDS EcolC_0712 NC_010468.1 764345 764905 D PFAM: conserved hypothetical protein; KEGG: sfx:S3229 hypothetical protein; hypothetical protein 764345..764905 Escherichia coli ATCC 8739 6066597 YP_001723715.1 CDS EcolC_0713 NC_010468.1 764936 766006 D PFAM: permease YjgP/YjgQ family protein; KEGG: sfx:S3228 hypothetical protein; YjgP/YjgQ family permease 764936..766006 Escherichia coli ATCC 8739 6067664 YP_001723716.1 CDS EcolC_0714 NC_010468.1 766003 767082 D PFAM: permease YjgP/YjgQ family protein; KEGG: sfx:S3227 hypothetical protein; YjgP/YjgQ family permease 766003..767082 Escherichia coli ATCC 8739 6066385 YP_001723717.1 CDS EcolC_0715 NC_010468.1 767117 768289 R PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: sfx:S3226 putative class II aminotransferase; 8-amino-7-oxononanoate synthase complement(767117..768289) Escherichia coli ATCC 8739 6066628 YP_001723718.1 CDS EcolC_0716 NC_010468.1 768289 768537 R PFAM: phosphopantetheine-binding; KEGG: sfx:S3224 hypothetical protein; phosphopantetheine-binding protein complement(768289..768537) Escherichia coli ATCC 8739 6067238 YP_001723719.1 CDS EcolC_0717 NC_010468.1 768569 769483 R PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: sfx:S3223 hypothetical protein; NAD-dependent epimerase/dehydratase complement(768569..769483) Escherichia coli ATCC 8739 6066081 YP_001723720.1 CDS EcolC_0718 NC_010468.1 769480 771201 R activates fatty acids by binding to coenzyme A; acyl-CoA synthetase complement(769480..771201) Escherichia coli ATCC 8739 6065986 YP_001723721.1 CDS EcolC_0719 NC_010468.1 771578 772720 D KEGG: sfv:SFV_3037 hypothetical protein; hypothetical protein 771578..772720 Escherichia coli ATCC 8739 6065828 YP_001723722.1 CDS EcolC_0720 NC_010468.1 772727 773491 R PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfx:S3220 transcriptional activator for glc operon; DNA-binding transcriptional regulator GlcC complement(772727..773491) Escherichia coli ATCC 8739 6064944 YP_001723723.1 CDS EcolC_0721 NC_010468.1 773742 775241 D TIGRFAM: glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein; KEGG: psa:PST_0431 glycolate oxidase, subunit GlcD; glycolate oxidase subunit GlcD 773742..775241 Escherichia coli ATCC 8739 6065831 YP_001723724.1 CDS glcE NC_010468.1 775241 776293 D PFAM: FAD linked oxidase domain protein; KEGG: psa:PST_0432 glycolate oxidase, subunit GlcE; glycolate oxidase FAD binding subunit 775241..776293 Escherichia coli ATCC 8739 6066610 YP_001723725.1 CDS glcF NC_010468.1 776304 777527 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: pmy:Pmen_0201 protein of unknown function DUF224, cysteine-rich region domain protein; glycolate oxidase iron-sulfur subunit 776304..777527 Escherichia coli ATCC 8739 6065809 YP_001723726.1 CDS EcolC_0724 NC_010468.1 777532 777936 D PFAM: protein of unknown function DUF336; KEGG: sfv:SFV_3032 hypothetical protein; hypothetical protein 777532..777936 Escherichia coli ATCC 8739 6064943 YP_001723727.1 CDS EcolC_0725 NC_010468.1 777958 780129 D catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 777958..780129 Escherichia coli ATCC 8739 6066053 YP_001723728.1 CDS EcolC_0726 NC_010468.1 780484 782166 D TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sfv:SFV_3030 putative permease; glycolate transporter 780484..782166 Escherichia coli ATCC 8739 6066074 YP_001723729.1 CDS EcolC_0727 NC_010468.1 782651 783082 D KEGG: ter:Tery_2591 cadherin; hypothetical protein 782651..783082 Escherichia coli ATCC 8739 6064976 YP_001723730.1 CDS EcolC_0728 NC_010468.1 783110 783409 D PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 783110..783409 Escherichia coli ATCC 8739 6067593 YP_001723731.1 CDS EcolC_0729 NC_010468.1 783406 784272 D PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 783406..784272 Escherichia coli ATCC 8739 6067680 YP_001723732.1 CDS EcolC_0730 NC_010468.1 784269 784913 R PFAM: HMG-I and HMG-Y DNA-binding domain protein; regulatory protein TetR; KEGG: kpn:KPN_02440 putative bacterial regulatory protein, TetR; TetR family transcriptional regulator complement(784269..784913) Escherichia coli ATCC 8739 6065751 YP_001723733.1 CDS EcolC_0732 NC_010468.1 785534 786337 R PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family; integrase catalytic subunit complement(785534..786337) Escherichia coli ATCC 8739 6064770 YP_001723734.1 CDS EcolC_0733 NC_010468.1 786385 786669 R PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein complement(786385..786669) Escherichia coli ATCC 8739 6065591 YP_001723735.1 CDS EcolC_0734 NC_010468.1 786762 788042 R TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: kpn:KPN_pKPN3p05958 secondary glycine betaine transporter BetU; choline/carnitine/betaine transporter complement(786762..788042) Escherichia coli ATCC 8739 6068703 YP_001723736.1 CDS EcolC_0735 NC_010468.1 788190 789008 R PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2; integrase catalytic subunit complement(788190..789008) Escherichia coli ATCC 8739 6066823 YP_001723737.1 CDS EcolC_0736 NC_010468.1 789093 790244 R PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30; integrase catalytic subunit complement(789093..790244) Escherichia coli ATCC 8739 6067024 YP_001723738.1 CDS EcolC_0738 NC_010468.1 791296 791553 D KEGG: eca:ECA2935 hypothetical protein; hypothetical protein 791296..791553 Escherichia coli ATCC 8739 6065032 YP_001723739.1 CDS fecE NC_010468.1 792111 792878 R Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit complement(792111..792878) Escherichia coli ATCC 8739 6065763 YP_001723740.1 CDS fecD NC_010468.1 792879 793835 R Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD complement(792879..793835) Escherichia coli ATCC 8739 6065119 YP_001723741.1 CDS fecC NC_010468.1 793832 794830 R part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease complement(793832..794830) Escherichia coli ATCC 8739 6065114 YP_001723742.1 CDS fecB NC_010468.1 794827 795729 R part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit complement(794827..795729) Escherichia coli ATCC 8739 6065947 YP_001723743.1 CDS EcolC_0743 NC_010468.1 795774 798098 R TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB short domain; TonB-dependent receptor plug; KEGG: sdy:SDY_4297 citrate-dependent iron transport, outer membrane receptor; TonB-dependent siderophore receptor complement(795774..798098) Escherichia coli ATCC 8739 6064739 YP_001723744.1 CDS EcolC_0744 NC_010468.1 798185 799138 R with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR complement(798185..799138) Escherichia coli ATCC 8739 6066577 YP_001723745.1 CDS EcolC_0745 NC_010468.1 799135 799656 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI complement(799135..799656) Escherichia coli ATCC 8739 6066802 YP_001723746.1 CDS EcolC_0747 NC_010468.1 800831 802093 R PFAM: integrase family protein; KEGG: sfx:S4822 putative P4-type integrase; integrase family protein complement(800831..802093) Escherichia coli ATCC 8739 6067103 YP_001723747.1 CDS EcolC_0748 NC_010468.1 802472 803179 R PFAM: protein of unknown function DUF554; KEGG: ssn:SSON_3229 putative transport protein; hypothetical protein complement(802472..803179) Escherichia coli ATCC 8739 6067162 YP_001723748.1 CDS EcolC_0749 NC_010468.1 803577 805712 D PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sfx:S3165 ornithine decarboxylase isozyme; ornithine decarboxylase 803577..805712 Escherichia coli ATCC 8739 6065463 YP_001723749.1 CDS EcolC_0750 NC_010468.1 805762 807018 R TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: sbo:SBO_3026 NupG; nucleoside transporter complement(805762..807018) Escherichia coli ATCC 8739 6066852 YP_001723750.1 CDS mltC NC_010468.1 807220 808302 R Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C complement(807220..808302) Escherichia coli ATCC 8739 6066511 YP_001723751.1 CDS EcolC_0752 NC_010468.1 808364 808639 R PFAM: Fe(II) trafficking protein YggX; KEGG: sdy:SDY_3110 hypothetical protein; hypothetical protein complement(808364..808639) Escherichia coli ATCC 8739 6064938 YP_001723752.1 CDS EcolC_0753 NC_010468.1 808667 809719 R KEGG: sbo:SBO_3029 adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; adenine DNA glycosylase complement(808667..809719) Escherichia coli ATCC 8739 6064935 YP_001723753.1 CDS trmB NC_010468.1 809880 810599 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 809880..810599 Escherichia coli ATCC 8739 6067160 YP_001723754.1 CDS EcolC_0755 NC_010468.1 810599 810925 D PFAM: protein of unknown function DUF469; KEGG: sdy:SDY_3113 hypothetical protein; hypothetical protein 810599..810925 Escherichia coli ATCC 8739 6067158 YP_001723755.1 CDS EcolC_0756 NC_010468.1 811109 811828 D KEGG: sdy:SDY_3114 hypothetical protein; hypothetical protein 811109..811828 Escherichia coli ATCC 8739 6067155 YP_001723756.1 CDS ansB NC_010468.1 812004 813050 D catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 812004..813050 Escherichia coli ATCC 8739 6066402 YP_001723757.1 CDS EcolC_0758 NC_010468.1 813167 814174 D PFAM: protein of unknown function DUF1202; KEGG: sbo:SBO_3034 putative alpha helix chain; hypothetical protein 813167..814174 Escherichia coli ATCC 8739 6065893 YP_001723758.1 CDS EcolC_0759 NC_010468.1 814329 815465 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(814329..815465) Escherichia coli ATCC 8739 6066690 YP_001723759.1 CDS EcolC_0760 NC_010468.1 815458 816051 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase complement(815458..816051) Escherichia coli ATCC 8739 6066447 YP_001723760.1 CDS EcolC_0761 NC_010468.1 816059 816349 R PFAM: protein of unknown function DUF167; KEGG: sfv:SFV_3007 hypothetical protein; hypothetical protein complement(816059..816349) Escherichia coli ATCC 8739 6065585 YP_001723761.1 CDS EcolC_0762 NC_010468.1 816346 816912 R PFAM: protein of unknown function YGGT; KEGG: sdy:SDY_3120 putative resistance protein; hypothetical protein complement(816346..816912) Escherichia coli ATCC 8739 6064825 YP_001723762.1 CDS EcolC_0763 NC_010468.1 816930 817634 R PFAM: alanine racemase domain protein; KEGG: sdy:SDY_3122 hypothetical protein; alanine racemase domain-containing protein complement(816930..817634) Escherichia coli ATCC 8739 6065332 YP_001723763.1 CDS EcolC_0764 NC_010468.1 817652 818632 D KEGG: sfv:SFV_3004 putative protein transport; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; twitching motility protein 817652..818632 Escherichia coli ATCC 8739 6065216 YP_001723764.1 CDS EcolC_0765 NC_010468.1 818816 819232 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(818816..819232) Escherichia coli ATCC 8739 6065711 YP_001723765.1 CDS EcolC_0766 NC_010468.1 819232 819867 R PFAM: protein of unknown function DUF179; KEGG: sdy:SDY_3124 hypothetical protein; hypothetical protein complement(819232..819867) Escherichia coli ATCC 8739 6064923 YP_001723766.1 CDS EcolC_0767 NC_010468.1 819904 820854 R catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase complement(819904..820854) Escherichia coli ATCC 8739 6064899 YP_001723767.1 CDS EcolC_0768 NC_010468.1 820867 821598 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(820867..821598) Escherichia coli ATCC 8739 6064919 YP_001723768.1 CDS EcolC_0769 NC_010468.1 821678 822385 R PFAM: Endonuclease I; KEGG: sbo:SBO_3045 DNA-specific endonuclease I; deoxyribonuclease I complement(821678..822385) Escherichia coli ATCC 8739 6065547 YP_001723769.1 CDS EcolC_0770 NC_010468.1 822480 822935 R PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: sbo:SBO_3046 hypothetical protein; hypothetical protein complement(822480..822935) Escherichia coli ATCC 8739 6065544 YP_001723770.1 CDS EcolC_0771 NC_010468.1 823054 824448 R KEGG: sdy:SDY_3129 galactose-proton symport of transport system; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; sugar transporter complement(823054..824448) Escherichia coli ATCC 8739 6066714 YP_001723771.1 CDS EcolC_0772 NC_010468.1 824884 826038 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(824884..826038) Escherichia coli ATCC 8739 6066565 YP_001723772.1 CDS EcolC_0773 NC_010468.1 826833 828809 D catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 826833..828809 Escherichia coli ATCC 8739 6065520 YP_001723773.1 CDS EcolC_0774 NC_010468.1 828947 829867 D catalyzes the formation of putrescine from agmatine; agmatinase 828947..829867 Escherichia coli ATCC 8739 6066730 YP_001723774.1 CDS EcolC_0775 NC_010468.1 830073 830831 R PFAM: peptidase M48 Ste24p; KEGG: sbo:SBO_3053 hypothetical protein; peptidase M48 Ste24p complement(830073..830831) Escherichia coli ATCC 8739 6066006 YP_001723775.1 CDS EcolC_0776 NC_010468.1 831109 833100 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 831109..833100 Escherichia coli ATCC 8739 6066655 YP_001723776.1 CDS cmtB NC_010468.1 833414 833857 D TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; putative mannitol phosphotransferase subunit EIIA 833414..833857 Escherichia coli ATCC 8739 6065402 YP_001723777.1 CDS EcolC_0778 NC_010468.1 833885 835273 D TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: sdy:SDY_3144 PTS system, mannitol-specific enzyme II component, cryptic; PTS system mannitol-specific transporter subunit IIC 833885..835273 Escherichia coli ATCC 8739 6066569 YP_001723778.1 CDS EcolC_0779 NC_010468.1 835288 836565 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfv:SFV_2983 putative oxidoreductase; alcohol dehydrogenase 835288..836565 Escherichia coli ATCC 8739 6065758 YP_001723779.1 CDS EcolC_0780 NC_010468.1 836562 837527 D TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sfv:SFV_2982 hypothetical protein; fructose-1,6-bisphosphatase II-like protein 836562..837527 Escherichia coli ATCC 8739 6064608 YP_001723780.1 CDS EcolC_0781 NC_010468.1 837549 838058 D PFAM: Mannitol repressor; KEGG: sdy:SDY_3147 putative transcriptional regulator; putative DNA-binding transcriptional regulator 837549..838058 Escherichia coli ATCC 8739 6066651 YP_001723781.1 CDS frcK NC_010468.1 838055 838768 D KEGG: sbo:SBO_3060 putative kinase; putative fructose transport system kinase 838055..838768 Escherichia coli ATCC 8739 6065053 YP_001723782.1 CDS EcolC_0783 NC_010468.1 839053 840072 D NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 839053..840072 Escherichia coli ATCC 8739 6066654 YP_001723783.1 CDS pgk NC_010468.1 840122 841285 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 840122..841285 Escherichia coli ATCC 8739 6067318 YP_001723784.1 CDS EcolC_0785 NC_010468.1 841500 842579 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 841500..842579 Escherichia coli ATCC 8739 6065450 YP_001723785.1 CDS EcolC_0786 NC_010468.1 842937 843797 D participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 842937..843797 Escherichia coli ATCC 8739 6065892 YP_001723786.1 CDS EcolC_0787 NC_010468.1 843936 844571 D Involved in the export of arginine; arginine exporter protein 843936..844571 Escherichia coli ATCC 8739 6067460 YP_001723787.1 CDS EcolC_0788 NC_010468.1 844664 845404 D PFAM: protein of unknown function DUF541; KEGG: sdy:SDY_3160 putative actin; hypothetical protein 844664..845404 Escherichia coli ATCC 8739 6066088 YP_001723788.1 CDS EcolC_0789 NC_010468.1 845571 846467 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3073 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 845571..846467 Escherichia coli ATCC 8739 6065839 YP_001723789.1 CDS EcolC_0790 NC_010468.1 846464 847942 R KEGG: ssn:SSON_3071 putative coenzyme A transferase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase; succinate CoA transferase complement(846464..847942) Escherichia coli ATCC 8739 6065725 YP_001723790.1 CDS EcolC_0791 NC_010468.1 847966 848751 R catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase complement(847966..848751) Escherichia coli ATCC 8739 6065086 YP_001723791.1 CDS EcolC_0792 NC_010468.1 848762 849757 R functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase complement(848762..849757) Escherichia coli ATCC 8739 6066499 YP_001723792.1 CDS EcolC_0793 NC_010468.1 849750 851894 R MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase complement(849750..851894) Escherichia coli ATCC 8739 6064709 YP_001723793.1 CDS EcolC_0794 NC_010468.1 852098 852991 R specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein complement(852098..852991) Escherichia coli ATCC 8739 6065256 YP_001723794.1 CDS EcolC_0795 NC_010468.1 853133 853363 D hypothetical protein 853133..853363 Escherichia coli ATCC 8739 6066586 YP_001723795.1 CDS EcolC_0796 NC_010468.1 853419 854078 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 853419..854078 Escherichia coli ATCC 8739 6066156 YP_001723796.1 CDS EcolC_0797 NC_010468.1 854334 855566 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 854334..855566 Escherichia coli ATCC 8739 6066820 YP_001723797.1 CDS EcolC_0798 NC_010468.1 855955 856557 R ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase complement(855955..856557) Escherichia coli ATCC 8739 6065342 YP_001723798.1 CDS EcolC_0799 NC_010468.1 856803 857132 R PFAM: protein of unknown function DUF710; KEGG: sbo:SBO_3082 hypothetical protein; Z-ring-associated protein complement(856803..857132) Escherichia coli ATCC 8739 6065404 YP_001723799.2 CDS EcolC_0800 NC_010468.1 857300 857878 D the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 857300..857878 Escherichia coli ATCC 8739 6066670 YP_001723800.1 CDS EcolC_0801 NC_010468.1 857904 859229 D exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 857904..859229 Escherichia coli ATCC 8739 6066555 YP_001723801.1 CDS EcolC_0802 NC_010468.1 859226 860404 D Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 859226..860404 Escherichia coli ATCC 8739 6065322 YP_001723802.1 CDS EcolC_0803 NC_010468.1 860427 861629 D TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: ssn:SSON_3059 hypothetical protein; hypothetical protein 860427..861629 Escherichia coli ATCC 8739 6065780 YP_001723803.1 CDS gcvT NC_010468.1 862077 863171 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 862077..863171 Escherichia coli ATCC 8739 6065305 YP_001723804.1 CDS EcolC_0805 NC_010468.1 863195 863584 D part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 863195..863584 Escherichia coli ATCC 8739 6066682 YP_001723805.1 CDS EcolC_0806 NC_010468.1 863703 866576 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 863703..866576 Escherichia coli ATCC 8739 6064873 YP_001723806.1 CDS EcolC_0807 NC_010468.1 866843 867586 D PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sfx:S3087 putative oxidoreductase; hypothetical protein 866843..867586 Escherichia coli ATCC 8739 6065924 YP_001723807.1 CDS EcolC_0808 NC_010468.1 867643 869076 R PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_3054 6-phospho-beta-glucosidase A, cryptic; glycoside hydrolase family protein complement(867643..869076) Escherichia coli ATCC 8739 6065927 YP_001723808.1 CDS EcolC_0809 NC_010468.1 869121 869432 D PFAM: protein of unknown function DUF437; KEGG: sdy:SDY_3181 hypothetical protein; hypothetical protein 869121..869432 Escherichia coli ATCC 8739 6064660 YP_001723809.1 CDS EcolC_0810 NC_010468.1 869596 870255 D TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: ssn:SSON_3052 putative oxidoreductase; hemolysin III family channel protein 869596..870255 Escherichia coli ATCC 8739 6066548 YP_001723810.1 CDS EcolC_0811 NC_010468.1 870451 871431 R physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator complement(870451..871431) Escherichia coli ATCC 8739 6066545 YP_001723811.1 CDS EcolC_0812 NC_010468.1 871674 871940 D PFAM: protein of unknown function DUF339; KEGG: sdy:SDY_3185 hypothetical protein; hypothetical protein 871674..871940 Escherichia coli ATCC 8739 6065645 YP_001723812.1 CDS EcolC_0813 NC_010468.1 871921 872328 D PFAM: protein of unknown function DUF1434; KEGG: sbo:SBO_3096 hypothetical protein; hypothetical protein 871921..872328 Escherichia coli ATCC 8739 6064732 YP_001723813.1 CDS EcolC_0814 NC_010468.1 872368 872889 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB complement(872368..872889) Escherichia coli ATCC 8739 6065811 YP_001723814.1 CDS xerD NC_010468.1 873001 873897 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 873001..873897 Escherichia coli ATCC 8739 6066903 YP_001723815.1 CDS EcolC_0816 NC_010468.1 873922 874632 D DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 873922..874632 Escherichia coli ATCC 8739 6065861 YP_001723816.1 CDS EcolC_0817 NC_010468.1 874638 876371 D 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 874638..876371 Escherichia coli ATCC 8739 6066416 YP_001723817.1 CDS prfB NC_010468.1 876462 877560 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 join(876462..876536,876538..877560) Escherichia coli ATCC 8739 6065042 YP_001723818.1 CDS lysS NC_010468.1 877570 879087 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 877570..879087 Escherichia coli ATCC 8739 6066114 YP_001723819.1 CDS EcolC_0820 NC_010468.1 879130 879678 R catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase complement(879130..879678) Escherichia coli ATCC 8739 6064889 YP_001723820.1 CDS EcolC_0821 NC_010468.1 879928 881376 R TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3041 putative permease; xanthine permease complement(879928..881376) Escherichia coli ATCC 8739 6066763 YP_001723821.1 CDS EcolC_0822 NC_010468.1 881812 883731 D unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 881812..883731 Escherichia coli ATCC 8739 6065417 YP_001723822.1 CDS EcolC_0823 NC_010468.1 883731 884219 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_3038 putative oxidoreductase, Fe-S subunit; 4Fe-4S ferredoxin 883731..884219 Escherichia coli ATCC 8739 6064729 YP_001723823.1 CDS EcolC_0824 NC_010468.1 884255 885622 R PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: spe:Spro_4431 xanthine/uracil/vitamin C permease; xanthine/uracil/vitamin C permease complement(884255..885622) Escherichia coli ATCC 8739 6066760 YP_001723824.1 CDS EcolC_0825 NC_010468.1 885658 886974 R Catalyzes the deamination of guanine; guanine deaminase complement(885658..886974) Escherichia coli ATCC 8739 6067212 YP_001723825.1 CDS EcolC_0826 NC_010468.1 886992 888392 R TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: aha:AHA_2174 xanthine/uracil permease family protein; uracil-xanthine permease complement(886992..888392) Escherichia coli ATCC 8739 6065500 YP_001723826.1 CDS EcolC_0827 NC_010468.1 888557 891427 R with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN complement(888557..891427) Escherichia coli ATCC 8739 6065961 YP_001723827.1 CDS EcolC_0828 NC_010468.1 891424 892203 R with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM complement(891424..892203) Escherichia coli ATCC 8739 6065301 YP_001723828.1 CDS EcolC_0829 NC_010468.1 892254 893582 R in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase complement(892254..893582) Escherichia coli ATCC 8739 6065278 YP_001723829.1 CDS EcolC_0830 NC_010468.1 893585 896683 R with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK complement(893585..896683) Escherichia coli ATCC 8739 6065389 YP_001723830.1 CDS EcolC_0831 NC_010468.1 897005 897520 R KEGG: ssn:SSON_3028 hypothetical protein; hypothetical protein complement(897005..897520) Escherichia coli ATCC 8739 6066696 YP_001723831.1 CDS EcolC_0832 NC_010468.1 897686 898456 D KEGG: ssn:SSON_3027 hypothetical protein; hypothetical protein 897686..898456 Escherichia coli ATCC 8739 6064450 YP_001723832.1 CDS EcolC_0833 NC_010468.1 898504 900129 D TIGRFAM: selenium-dependent molybdenum hydroxylase system protein, YqeB family; PFAM: biotin/lipoyl attachment domain-containing protein; protein of unknown function DUF182; KEGG: sbo:SBO_3109 putative synthase; selenium-dependent molybdenum hydroxylase system protein 898504..900129 Escherichia coli ATCC 8739 6067086 YP_001723833.1 CDS EcolC_0834 NC_010468.1 900350 901282 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(900350..901282) Escherichia coli ATCC 8739 6065851 YP_001723834.1 CDS EcolC_0835 NC_010468.1 901330 902715 R catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase complement(901330..902715) Escherichia coli ATCC 8739 6065012 YP_001723835.1 CDS EcolC_0836 NC_010468.1 902768 903979 R Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase complement(902768..903979) Escherichia coli ATCC 8739 6066008 YP_001723836.1 CDS EcolC_0837 NC_010468.1 904037 905233 R catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase complement(904037..905233) Escherichia coli ATCC 8739 6065236 YP_001723837.1 CDS EcolC_0838 NC_010468.1 905291 906481 R TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: ssn:SSON_3021 putative carbamoyl transferase; aspartate/ornithine carbamoyltransferase family protein complement(905291..906481) Escherichia coli ATCC 8739 6066675 YP_001723838.1 CDS EcolC_0839 NC_010468.1 906957 908735 D PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: PAS domain containing protein; AAA ATPase; KEGG: ssn:SSON_3020 putative transcriptional regulator; PAS modulated sigma54 specific transcriptional regulator 906957..908735 Escherichia coli ATCC 8739 6067240 YP_001723839.1 CDS EcolC_0840 NC_010468.1 908775 909254 R iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC complement(908775..909254) Escherichia coli ATCC 8739 6065539 YP_001723840.1 CDS EcolC_0841 NC_010468.1 909251 910129 R FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB complement(909251..910129) Escherichia coli ATCC 8739 6066027 YP_001723841.1 CDS EcolC_0842 NC_010468.1 910140 912437 R putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA complement(910140..912437) Escherichia coli ATCC 8739 6064964 YP_001723842.1 CDS EcolC_0843 NC_010468.1 912852 913607 D PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: ssn:SSON_3016 putative lipoprotein; peptidase M23B 912852..913607 Escherichia coli ATCC 8739 6066656 YP_001723843.1 CDS EcolC_0844 NC_010468.1 913985 915607 D KEGG: ssn:SSON_3014 hypothetical protein; hypothetical protein 913985..915607 Escherichia coli ATCC 8739 6066891 YP_001723844.1 CDS EcolC_0845 NC_010468.1 915739 916686 D involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; surface presentation of antigens protein SpaO 915739..916686 Escherichia coli ATCC 8739 6066263 YP_001723845.1 CDS spaP NC_010468.1 916676 917341 D part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP 916676..917341 Escherichia coli ATCC 8739 6066702 YP_001723846.1 CDS EcolC_0847 NC_010468.1 917351 917611 D TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ family 3; KEGG: cvi:CV_2623 surface presentation of antigens; secretory proteins; HrpO family type III secretion protein 917351..917611 Escherichia coli ATCC 8739 6067332 YP_001723847.1 CDS EcolC_0848 NC_010468.1 917613 918380 D TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: cvi:CV_2622 surface presentation of antigens; secretory proteins; type III secretion protein SpaR/YscT/HrcT 917613..918380 Escherichia coli ATCC 8739 6067644 YP_001723848.1 CDS EcolC_0850 NC_010468.1 919865 920365 R PFAM: regulatory protein LuxR; LuxR family transcriptional regulator complement(919865..920365) Escherichia coli ATCC 8739 6065283 YP_001723849.1 CDS EcolC_0851 NC_010468.1 920622 921803 D TIGRFAM: type III secretion system protein PrgH/EprH; PFAM: Type III secretion system PrgH/EprHfmaily protein; KEGG: stt:t2776 pathogenicity 1 island effector protein; type III secretion system protein PrgH/EprH 920622..921803 Escherichia coli ATCC 8739 6064965 YP_001723850.1 CDS EcolC_0852 NC_010468.1 921841 922056 D TIGRFAM: type III secretion system needle protein; KEGG: cvi:CV_2422 cell invasion protein - cytoplasmic; type III secretion system needle protein 921841..922056 Escherichia coli ATCC 8739 6067002 YP_001723851.1 CDS EcolC_0853 NC_010468.1 922076 922408 D KEGG: cvi:CV_2421 cell invasion protein - cytoplasmic; hypothetical protein 922076..922408 Escherichia coli ATCC 8739 6064409 YP_001723852.1 CDS EcolC_0855 NC_010468.1 922824 923521 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(922824..923267,923267..923521)) Escherichia coli ATCC 8739 6064366 YP_001723853.1 CDS EcolC_0857 NC_010468.1 924530 924724 D hypothetical protein 924530..924724 Escherichia coli ATCC 8739 6065171 YP_001723854.1 CDS EcolC_0858 NC_010468.1 924727 925158 D hypothetical protein 924727..925158 Escherichia coli ATCC 8739 6065137 YP_001723855.1 CDS EcolC_0859 NC_010468.1 925377 926009 D PFAM: regulatory protein LuxR; response regulator receiver; KEGG: sgl:SG1279 putative two-component response regulator; two component LuxR family transcriptional regulator 925377..926009 Escherichia coli ATCC 8739 6065122 YP_001723856.1 CDS EcolC_0860 NC_010468.1 926054 926428 R PFAM: Lytic transglycosylase catalytic; KEGG: stt:t4248 hypothetical protein; lytic transglycosylase complement(926054..926428) Escherichia coli ATCC 8739 6065081 YP_001723857.1 CDS EcolC_0861 NC_010468.1 926612 926830 R hypothetical protein complement(926612..926830) Escherichia coli ATCC 8739 6065070 YP_001723858.1 CDS EcolC_0862 NC_010468.1 926998 928374 R PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: cvi:CV_2640 invasion genes transcription activator; transcriptional regulator complement(926998..928374) Escherichia coli ATCC 8739 6065016 YP_001723859.1 CDS EcolC_0863 NC_010468.1 928709 929200 R PFAM: Tetratricopeptide TPR_3; KEGG: ssn:SSON_3011 hypothetical protein; hypothetical protein complement(928709..929200) Escherichia coli ATCC 8739 6065002 YP_001723860.1 CDS EcolC_0864 NC_010468.1 929467 929913 R KEGG: ssn:SSON_3010 hypothetical protein; hypothetical protein complement(929467..929913) Escherichia coli ATCC 8739 6064992 YP_001723861.1 CDS EcolC_0865 NC_010468.1 929967 930203 D hypothetical protein 929967..930203 Escherichia coli ATCC 8739 6064979 YP_001723862.1 CDS EcolC_0866 NC_010468.1 930343 930768 D hypothetical protein 930343..930768 Escherichia coli ATCC 8739 6064972 YP_001723863.1 CDS EcolC_0867 NC_010468.1 930917 931399 R KEGG: ssn:SSON_3009 hypothetical protein; hypothetical protein complement(930917..931399) Escherichia coli ATCC 8739 6064967 YP_001723864.1 CDS EcolC_0868 NC_010468.1 931392 932201 R PFAM: transcriptional regulator domain protein; KEGG: kpn:KPN_00272 putative sensory transducer; transcriptional regulator CadC complement(931392..932201) Escherichia coli ATCC 8739 6064942 YP_001723865.1 CDS EcolC_0869 NC_010468.1 932535 933167 R KEGG: ssn:SSON_3006 hypothetical protein; hypothetical protein complement(932535..933167) Escherichia coli ATCC 8739 6064902 YP_001723866.1 CDS EcolC_0870 NC_010468.1 933627 934856 R TIGRFAM: serine transporter; PFAM: Amino acid transporter transmembrane; KEGG: ssn:SSON_3005 putative transporter protein; serine transporter complement(933627..934856) Escherichia coli ATCC 8739 6064882 YP_001723867.1 CDS EcolC_0871 NC_010468.1 935111 936292 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 935111..936292 Escherichia coli ATCC 8739 6064856 YP_001723868.1 CDS EcolC_0872 NC_010468.1 936579 937415 D 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 936579..937415 Escherichia coli ATCC 8739 6064854 YP_001723869.1 CDS EcolC_0873 NC_010468.1 937445 938206 D catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 937445..938206 Escherichia coli ATCC 8739 6064842 YP_001723870.1 CDS EcolC_0874 NC_010468.1 938521 939939 D KEGG: ssn:SSON_3001 low-affinity L-arabinose transport system proton symport protein; TIGRFAM: sugar transporter; PFAM: General substrate transporter; major facilitator superfamily MFS_1; sugar transporter 938521..939939 Escherichia coli ATCC 8739 6064833 YP_001723871.1 CDS EcolC_0875 NC_010468.1 940068 940760 D TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: sfv:SFV_2918 putative resistance proteins; putative racemase 940068..940760 Escherichia coli ATCC 8739 6064817 YP_001723872.1 CDS EcolC_0876 NC_010468.1 940747 941682 R activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR complement(940747..941682) Escherichia coli ATCC 8739 6064811 YP_001723873.1 CDS EcolC_0877 NC_010468.1 941804 943066 D catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 941804..943066 Escherichia coli ATCC 8739 6064787 YP_001723874.1 CDS EcolC_0878 NC_010468.1 943073 944104 R controls transcription of galETKM; DNA-binding transcriptional regulator GalR complement(943073..944104) Escherichia coli ATCC 8739 6064784 YP_001723875.1 CDS EcolC_0879 NC_010468.1 944690 946849 D Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 944690..946849 Escherichia coli ATCC 8739 6064777 YP_001723876.1 CDS EcolC_0880 NC_010468.1 946842 948035 D PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2727 putative resistance proteins; lysophospholipid transporter LplT 946842..948035 Escherichia coli ATCC 8739 6064774 YP_001723877.1 CDS tas NC_010468.1 948067 949107 R complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase complement(948067..949107) Escherichia coli ATCC 8739 6064747 YP_001723878.1 CDS EcolC_0882 NC_010468.1 949215 949433 R PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3050 hypothetical protein; hypothetical protein complement(949215..949433) Escherichia coli ATCC 8739 6064734 YP_001723879.1 CDS EcolC_0883 NC_010468.1 949571 950284 R PFAM: Integral membrane protein TerC; KEGG: sdy:SDY_3049 putative transport protein; integral membrane protein TerC complement(949571..950284) Escherichia coli ATCC 8739 6064724 YP_001723880.1 CDS EcolC_0884 NC_010468.1 950353 951042 R MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein complement(950353..951042) Escherichia coli ATCC 8739 6064717 YP_001723881.1 CDS EcolC_0885 NC_010468.1 951727 952257 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 951727..952257 Escherichia coli ATCC 8739 6064710 YP_001723882.1 CDS EcolC_0886 NC_010468.1 952270 954516 D member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein 952270..954516 Escherichia coli ATCC 8739 6064693 YP_001723883.1 CDS EcolC_0887 NC_010468.1 954667 955542 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 954667..955542 Escherichia coli ATCC 8739 6064668 YP_001723884.1 CDS thyA NC_010468.1 955549 956343 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 955549..956343 Escherichia coli ATCC 8739 6064653 YP_001723885.1 CDS EcolC_0889 NC_010468.1 956528 956998 D KEGG: sdy:SDY_3043 prepilin peptidase dependent protein A; hypothetical protein 956528..956998 Escherichia coli ATCC 8739 6064641 YP_001723886.1 CDS EcolC_0890 NC_010468.1 956989 957552 D KEGG: ssn:SSON_2982 prepilin peptidase dependent protein B; hypothetical protein 956989..957552 Escherichia coli ATCC 8739 6064637 YP_001723887.1 CDS EcolC_0891 NC_010468.1 957549 957956 D KEGG: sfv:SFV_2902 hypothetical protein; hypothetical protein 957549..957956 Escherichia coli ATCC 8739 6064625 YP_001723888.1 CDS EcolC_0892 NC_010468.1 957941 958264 D KEGG: sbo:SBO_2713 prepilin peptidase dependent protein C; hypothetical protein 957941..958264 Escherichia coli ATCC 8739 6064623 YP_001723889.1 CDS recC NC_010468.1 958277 961645 D catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 958277..961645 Escherichia coli ATCC 8739 6064617 YP_001723890.1 CDS EcolC_0894 NC_010468.1 961821 964709 D PFAM: peptidase M16 domain protein; KEGG: sfv:SFV_2899 protease III; peptidase M16 domain-containing protein 961821..964709 Escherichia coli ATCC 8739 6064615 YP_001723891.1 CDS recB NC_010468.1 964702 968244 D helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 964702..968244 Escherichia coli ATCC 8739 6064606 YP_001723892.1 CDS recD NC_010468.1 968244 970070 D helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 968244..970070 Escherichia coli ATCC 8739 6064598 YP_001723893.1 CDS EcolC_0897 NC_010468.1 970132 971463 R catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase complement(970132..971463) Escherichia coli ATCC 8739 6064574 YP_001723894.1 CDS EcolC_0898 NC_010468.1 971695 972948 D PFAM: cell wall hydrolase/autolysin; KEGG: sbo:SBO_2707 putative amidase; N-acetylmuramoyl-L-alanine amidase 971695..972948 Escherichia coli ATCC 8739 6064549 YP_001723895.1 CDS mltA NC_010468.1 973527 974624 D membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 973527..974624 Escherichia coli ATCC 8739 6068719 YP_001723896.1 CDS EcolC_0900 NC_010468.1 974863 975669 D PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ssn:SSON_2969 putative enzyme; UBA/THIF-type NAD/FAD binding protein 974863..975669 Escherichia coli ATCC 8739 6068702 YP_001723897.1 CDS EcolC_0901 NC_010468.1 975720 976163 R TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: sdy:SDY_3029 hypothetical protein; cysteine desulfurase, sulfur acceptor subunit CsdE complement(975720..976163) Escherichia coli ATCC 8739 6068698 YP_001723898.1 CDS EcolC_0902 NC_010468.1 976163 977368 R TIGRFAM: cysteine desulfurase, catalytic subunit CsdA; PFAM: aminotransferase class V; KEGG: ssn:SSON_2967 hypothetical protein; cysteine sulfinate desulfinase complement(976163..977368) Escherichia coli ATCC 8739 6068689 YP_001723899.1 CDS EcolC_0903 NC_010468.1 977560 977787 D PFAM: protein of unknown function DUF903; KEGG: sdy:SDY_3027 hypothetical protein; hypothetical protein 977560..977787 Escherichia coli ATCC 8739 6068684 YP_001723900.1 CDS EcolC_0904 NC_010468.1 978138 979055 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 978138..979055 Escherichia coli ATCC 8739 6068677 YP_001723901.1 CDS EcolC_0905 NC_010468.1 979074 979469 D PFAM: protein of unknown function DUF423; KEGG: sdy:SDY_3025 hypothetical protein; hypothetical protein 979074..979469 Escherichia coli ATCC 8739 6068673 YP_001723902.1 CDS EcolC_0906 NC_010468.1 979462 980562 D KEGG: sfv:SFV_2885 hypothetical protein; putative RNA 2'-O-ribose methyltransferase 979462..980562 Escherichia coli ATCC 8739 6068668 YP_001723903.1 CDS EcolC_0907 NC_010468.1 980606 981337 R regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR complement(980606..981337) Escherichia coli ATCC 8739 6068663 YP_001723904.1 CDS EcolC_0908 NC_010468.1 981395 981817 R PFAM: RbsD or FucU transport; KEGG: sdy:SDY_3022 protein of fucose operon; transport protein RbsD/FucU complement(981395..981817) Escherichia coli ATCC 8739 6068657 YP_001723905.1 CDS EcolC_0909 NC_010468.1 981819 983237 R TIGRFAM: L-fuculokinase; PFAM: carbohydrate kinase FGGY; KEGG: ssn:SSON_2960 L-fuculokinase; L-fuculokinase complement(981819..983237) Escherichia coli ATCC 8739 6068653 YP_001723906.1 CDS fucI NC_010468.1 983346 985121 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(983346..985121) Escherichia coli ATCC 8739 6068643 YP_001723907.1 CDS EcolC_0911 NC_010468.1 985154 986470 R TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_2880 fucose permease; L-fucose transporter complement(985154..986470) Escherichia coli ATCC 8739 6068636 YP_001723908.1 CDS EcolC_0912 NC_010468.1 987017 987664 D catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 987017..987664 Escherichia coli ATCC 8739 6068632 YP_001723909.1 CDS EcolC_0913 NC_010468.1 987689 988840 D TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2956 L-1,2-propanediol oxidoreductase; L-1,2-propanediol oxidoreductase 987689..988840 Escherichia coli ATCC 8739 6068627 YP_001723910.1 CDS xni NC_010468.1 988895 989650 R has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX complement(988895..989650) Escherichia coli ATCC 8739 6068625 YP_001723911.1 CDS EcolC_0915 NC_010468.1 989762 991129 R KEGG: ssn:SSON_2954 L-serine dehydratase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 complement(989762..991129) Escherichia coli ATCC 8739 6068620 YP_001723912.1 CDS EcolC_0916 NC_010468.1 991187 992476 R TIGRFAM: serine transporter; KEGG: sbo:SBO_2677 probable serine transporter; serine transporter complement(991187..992476) Escherichia coli ATCC 8739 6068615 YP_001723913.1 CDS EcolC_0917 NC_010468.1 993033 994397 R PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2676 hypothetical protein; hypothetical protein complement(993033..994397) Escherichia coli ATCC 8739 6068613 YP_001723914.1 CDS queF NC_010468.1 994509 995357 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(994509..995357) Escherichia coli ATCC 8739 6068608 YP_001723915.1 CDS EcolC_0919 NC_010468.1 995425 995970 D putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 995425..995970 Escherichia coli ATCC 8739 6068604 YP_001723916.1 CDS EcolC_0920 NC_010468.1 996592 996921 D PFAM: protein of unknown function DUF446; KEGG: ssn:SSON_2949 hypothetical protein; hypothetical protein 996592..996921 Escherichia coli ATCC 8739 6068596 YP_001723917.1 CDS EcolC_0921 NC_010468.1 996921 997703 D catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 996921..997703 Escherichia coli ATCC 8739 6068584 YP_001723918.1 CDS EcolC_0922 NC_010468.1 997721 998170 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 997721..998170 Escherichia coli ATCC 8739 6068578 YP_001723919.1 CDS EcolC_0923 NC_010468.1 998605 999957 D TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2946 putative transport protein; d-galactonate transporter 998605..999957 Escherichia coli ATCC 8739 6068572 YP_001723920.1 CDS EcolC_0924 NC_010468.1 999959 1001299 D PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ssn:SSON_2945 putative glucarate dehydratase; mandelate racemase/muconate lactonizing protein 999959..1001299 Escherichia coli ATCC 8739 6068567 YP_001723921.1 CDS EcolC_0925 NC_010468.1 1001320 1002660 D KEGG: sfx:S2994 putative glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein; glucarate dehydratase 1001320..1002660 Escherichia coli ATCC 8739 6068564 YP_001723922.1 CDS EcolC_0926 NC_010468.1 1002893 1005649 R part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA complement(1002893..1005649) Escherichia coli ATCC 8739 6068560 YP_001723923.1 CDS rumA NC_010468.1 1005706 1007007 D in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 1005706..1007007 Escherichia coli ATCC 8739 6068545 YP_001723924.1 CDS relA NC_010468.1 1007055 1009289 D (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 1007055..1009289 Escherichia coli ATCC 8739 6068537 YP_001723925.1 CDS EcolC_0929 NC_010468.1 1009367 1009615 D part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 1009367..1009615 Escherichia coli ATCC 8739 6068532 YP_001723926.1 CDS EcolC_0930 NC_010468.1 1009639 1009950 D MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 1009639..1009950 Escherichia coli ATCC 8739 6068523 YP_001723927.1 CDS mazG NC_010468.1 1010021 1010812 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1010021..1010812 Escherichia coli ATCC 8739 6068518 YP_001723928.1 CDS pyrG NC_010468.1 1011040 1012677 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1011040..1012677 Escherichia coli ATCC 8739 6068514 YP_001723929.1 CDS eno NC_010468.1 1012765 1014063 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1012765..1014063 Escherichia coli ATCC 8739 6068506 YP_001723930.1 CDS EcolC_0934 NC_010468.1 1014123 1014995 R PFAM: protein of unknown function DUF477; KEGG: sfv:SFV_2677 hypothetical protein; hypothetical protein complement(1014123..1014995) Escherichia coli ATCC 8739 6068495 YP_001723931.1 CDS EcolC_0935 NC_010468.1 1015289 1015960 D KEGG: sdy:SDY_2981 hypothetical protein; hypothetical protein 1015289..1015960 Escherichia coli ATCC 8739 6068492 YP_001723932.1 CDS EcolC_0936 NC_010468.1 1017271 1018383 R PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein complement(1017271..1018383) Escherichia coli ATCC 8739 6068482 YP_001723933.1 CDS EcolC_0937 NC_010468.1 1020025 1021503 R PFAM: carbohydrate kinase FGGY; KEGG: sdy:SDY_2978 putative kinase; carbohydrate kinase FGGY complement(1020025..1021503) Escherichia coli ATCC 8739 6068454 YP_001723934.1 CDS EcolC_0938 NC_010468.1 1021530 1022807 R PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2927 putative transport protein; major facilitator transporter complement(1021530..1022807) Escherichia coli ATCC 8739 6068442 YP_001723935.1 CDS EcolC_0939 NC_010468.1 1023126 1023911 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_2976 putative oxidoreductase; short-chain dehydrogenase/reductase SDR 1023126..1023911 Escherichia coli ATCC 8739 6068435 YP_001723936.1 CDS EcolC_0940 NC_010468.1 1023981 1025435 D PFAM: FAD linked oxidase domain protein; KEGG: cko:CKO_04128 hypothetical protein; FAD linked oxidase domain-containing protein 1023981..1025435 Escherichia coli ATCC 8739 6068425 YP_001723937.1 CDS EcolC_0941 NC_010468.1 1025529 1026866 D PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_2924 putative transport protein; major facilitator transporter 1025529..1026866 Escherichia coli ATCC 8739 6068413 YP_001723938.1 CDS EcolC_0942 NC_010468.1 1026844 1027623 D PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: ssn:SSON_2923 putative transport protein; electron transfer flavoprotein subunit alpha/beta 1026844..1027623 Escherichia coli ATCC 8739 6068400 YP_001723939.1 CDS EcolC_0943 NC_010468.1 1027620 1028480 D PFAM: Electron transfer flavoprotein alpha subunit; KEGG: ssn:SSON_2922 putative flavoprotein; electron transfer flavoprotein subunit alpha 1027620..1028480 Escherichia coli ATCC 8739 6068383 YP_001723940.1 CDS EcolC_0944 NC_010468.1 1028628 1029203 R PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: sdy:SDY_2970 putative anti-terminator regulatory protein; glycerol-3-phosphate responsive antiterminator GlpP complement(1028628..1029203) Escherichia coli ATCC 8739 6068376 YP_001723941.1 CDS EcolC_0945 NC_010468.1 1029220 1029480 R KEGG: sdy:SDY_2969 hypothetical protein; hypothetical protein complement(1029220..1029480) Escherichia coli ATCC 8739 6068374 YP_001723942.1 CDS EcolC_0946 NC_010468.1 1029471 1030742 R PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2919 hypothetical protein; electron-transferring-flavoprotein dehydrogenase complement(1029471..1030742) Escherichia coli ATCC 8739 6068366 YP_001723943.1 CDS EcolC_0947 NC_010468.1 1030820 1031185 R KEGG: sbo:SBO_2649 putative 6-pyruvoyl tetrahydrobiopterin synthase; TIGRFAM: 6-pyruvoyl tetrahydropterin synthase; queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; 6-pyruvoyl-tetrahydropterin synthase complement(1030820..1031185) Escherichia coli ATCC 8739 6068359 YP_001723944.1 CDS cysJ NC_010468.1 1031501 1033300 D catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 1031501..1033300 Escherichia coli ATCC 8739 6068352 YP_001723945.1 CDS EcolC_0949 NC_010468.1 1033300 1035012 D hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 1033300..1035012 Escherichia coli ATCC 8739 6068350 YP_001723946.1 CDS EcolC_0950 NC_010468.1 1035087 1035821 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 1035087..1035821 Escherichia coli ATCC 8739 6068347 YP_001723947.1 CDS EcolC_0951 NC_010468.1 1036180 1038846 D KEGG: gsu:GSU1384 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; hypothetical protein 1036180..1038846 Escherichia coli ATCC 8739 6068341 YP_001723948.1 CDS EcolC_0952 NC_010468.1 1039261 1040769 D unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein 1039261..1040769 Escherichia coli ATCC 8739 6068332 YP_001723949.1 CDS EcolC_0953 NC_010468.1 1040762 1041244 D TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2; KEGG: gsu:GSU1386 hypothetical protein; CRISPR-associated Cse2 family protein 1040762..1041244 Escherichia coli ATCC 8739 6068315 YP_001723950.1 CDS EcolC_0954 NC_010468.1 1041257 1042348 D TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CRISPR-associated protein CT1975; KEGG: gsu:GSU1387 CRISPR-associated CT1975 family protein; CRISPR-associated Cse4 family protein 1041257..1042348 Escherichia coli ATCC 8739 6068312 YP_001723951.1 CDS EcolC_0955 NC_010468.1 1042351 1043025 D TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: gsu:GSU1388 CRISPR-associated CT1976 family protein; CRISPR-associated Cas5 family protein 1042351..1043025 Escherichia coli ATCC 8739 6068303 YP_001723952.1 CDS EcolC_0956 NC_010468.1 1043012 1043611 D TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: sdy:SDY_2955 hypothetical protein; CRISPR-associated Cse3 family protein 1043012..1043611 Escherichia coli ATCC 8739 6068298 YP_001723953.1 CDS EcolC_0957 NC_010468.1 1043627 1044544 D TIGRFAM: CRISPR-associated protein Cas1; KEGG: stt:t2839 hypothetical protein; CRISPR-associated Cas1 family protein 1043627..1044544 Escherichia coli ATCC 8739 6068290 YP_001723954.1 CDS EcolC_0958 NC_010468.1 1044546 1044830 D TIGRFAM: CRISPR-associated protein Cas2; KEGG: sdy:SDY_2953 hypothetical protein; hypothetical protein 1044546..1044830 Escherichia coli ATCC 8739 6068280 YP_001723955.1 CDS EcolC_0959 NC_010468.1 1046266 1047303 R catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase complement(1046266..1047303) Escherichia coli ATCC 8739 6068256 YP_001723956.1 CDS EcolC_0960 NC_010468.1 1047555 1048463 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 1047555..1048463 Escherichia coli ATCC 8739 6068236 YP_001723957.1 CDS cysN NC_010468.1 1048465 1049892 D may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 1048465..1049892 Escherichia coli ATCC 8739 6068229 YP_001723958.1 CDS EcolC_0962 NC_010468.1 1049892 1050497 D converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 1049892..1050497 Escherichia coli ATCC 8739 6068220 YP_001723959.1 CDS EcolC_0963 NC_010468.1 1050547 1050870 D KEGG: sdy:SDY_2948 putative cytochrome oxidase subunit; hypothetical protein 1050547..1050870 Escherichia coli ATCC 8739 6068216 YP_001723960.1 CDS ftsB NC_010468.1 1051064 1051375 D forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 1051064..1051375 Escherichia coli ATCC 8739 6068212 YP_001723961.1 CDS ispD NC_010468.1 1051394 1052104 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1051394..1052104 Escherichia coli ATCC 8739 6068206 YP_001723962.1 CDS ispF NC_010468.1 1052104 1052583 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1052104..1052583 Escherichia coli ATCC 8739 6068194 YP_001723963.1 CDS truD NC_010468.1 1052580 1053629 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 1052580..1053629 Escherichia coli ATCC 8739 6068181 YP_001723964.1 CDS surE NC_010468.1 1053610 1054371 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 1053610..1054371 Escherichia coli ATCC 8739 6068171 YP_001723965.1 CDS pcm NC_010468.1 1054365 1054991 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 1054365..1054991 Escherichia coli ATCC 8739 6068153 YP_001723966.1 CDS nlpD NC_010468.1 1055131 1056270 D outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 1055131..1056270 Escherichia coli ATCC 8739 6068029 YP_001723967.1 CDS EcolC_0971 NC_010468.1 1056333 1057325 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 1056333..1057325 Escherichia coli ATCC 8739 6068014 YP_001723968.1 CDS EcolC_0972 NC_010468.1 1057419 1058783 R member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN complement(1057419..1058783) Escherichia coli ATCC 8739 6067975 YP_001723969.1 CDS EcolC_0973 NC_010468.1 1058872 1059648 R PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sbo:SBO_2781 hypothetical protein; hypothetical protein complement(1058872..1059648) Escherichia coli ATCC 8739 6067951 YP_001723970.1 CDS EcolC_0974 NC_010468.1 1059653 1060291 R PFAM: class II aldolase/adducin family protein; KEGG: sbo:SBO_2782 putative epimerase/aldolase; putative aldolase complement(1059653..1060291) Escherichia coli ATCC 8739 6067930 YP_001723971.1 CDS EcolC_0975 NC_010468.1 1060288 1061550 R PFAM: type III effector Hrp-dependent outers; KEGG: ssn:SSON_2885 hypothetical protein; Hrp-dependent type III effector protein complement(1060288..1061550) Escherichia coli ATCC 8739 6067922 YP_001723972.1 CDS EcolC_0976 NC_010468.1 1061547 1062455 R PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ssn:SSON_2884 putative dehydrogenase; 2-hydroxy-3-oxopropionate reductase complement(1061547..1062455) Escherichia coli ATCC 8739 6067893 YP_001723973.1 CDS EcolC_0977 NC_010468.1 1062651 1063418 D PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sbo:SBO_2785 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 1062651..1063418 Escherichia coli ATCC 8739 6067882 YP_001723974.1 CDS EcolC_0978 NC_010468.1 1063619 1064316 D PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein join(1063619..1063873,1063873..1064316) Escherichia coli ATCC 8739 6067877 YP_001723975.1 CDS EcolC_0979 NC_010468.1 1064408 1066969 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(1064408..1066969) Escherichia coli ATCC 8739 6067846 YP_001723976.1 CDS EcolC_0980 NC_010468.1 1067256 1067609 D KEGG: sbo:SBO_2788 hypothetical protein; hypothetical protein 1067256..1067609 Escherichia coli ATCC 8739 6067815 YP_001723977.1 CDS EcolC_0981 NC_010468.1 1067646 1069724 R PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2789 formate hydrogen-lyase transcriptional activator for FdhF, hyc and hyp operons; NifA subfamily transcriptional regulator complement(1067646..1069724) Escherichia coli ATCC 8739 6067810 YP_001723978.1 CDS EcolC_0982 NC_010468.1 1069798 1070808 R TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: ssn:SSON_2877 HypE; hydrogenase expression/formation protein HypE complement(1069798..1070808) Escherichia coli ATCC 8739 6067804 YP_001723979.1 CDS EcolC_0983 NC_010468.1 1070805 1071926 R TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: sbo:SBO_2791 HypD; hydrogenase expression/formation protein HypD complement(1070805..1071926) Escherichia coli ATCC 8739 6067799 YP_001723980.1 CDS EcolC_0984 NC_010468.1 1071926 1072198 R HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone complement(1071926..1072198) Escherichia coli ATCC 8739 6067796 YP_001723981.1 CDS EcolC_0985 NC_010468.1 1072189 1073061 R GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB complement(1072189..1073061) Escherichia coli ATCC 8739 6067791 YP_001723982.1 CDS hypA NC_010468.1 1073065 1073415 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein complement(1073065..1073415) Escherichia coli ATCC 8739 6067788 YP_001723983.1 CDS EcolC_0987 NC_010468.1 1073627 1074088 D regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 1073627..1074088 Escherichia coli ATCC 8739 6067776 YP_001723984.1 CDS EcolC_0988 NC_010468.1 1074213 1074824 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2779 probable small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex); 4Fe-4S ferredoxin 1074213..1074824 Escherichia coli ATCC 8739 6067770 YP_001723985.1 CDS EcolC_0989 NC_010468.1 1074821 1076647 D catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 1074821..1076647 Escherichia coli ATCC 8739 6067766 YP_001723986.1 CDS EcolC_0990 NC_010468.1 1076650 1077573 D PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: sbo:SBO_2796 membrane-spanning protein of hydrogenase 3; respiratory-chain NADH dehydrogenase subunit 1 1076650..1077573 Escherichia coli ATCC 8739 6067758 YP_001723987.1 CDS EcolC_0991 NC_010468.1 1077591 1079300 D PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: sbo:SBO_2797 large subunit of hydrogenase 3; NADH dehydrogenase (ubiquinone) 30 kDa subunit 1077591..1079300 Escherichia coli ATCC 8739 6067744 YP_001723988.1 CDS EcolC_0992 NC_010468.1 1079310 1079852 D electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 1079310..1079852 Escherichia coli ATCC 8739 6067741 YP_001723989.1 CDS EcolC_0993 NC_010468.1 1079852 1080619 D PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: sfv:SFV_2784 hydrogenase activity; NADH ubiquinone oxidoreductase 20 kDa subunit 1079852..1080619 Escherichia coli ATCC 8739 6067739 YP_001723990.1 CDS EcolC_0994 NC_010468.1 1080616 1081026 D PFAM: formate hydrogenlyase maturation HycH; KEGG: sbo:SBO_2800 processing of large subunit (HycE) of hydrogenase 3; formate hydrogenlyase maturation HycH 1080616..1081026 Escherichia coli ATCC 8739 6067736 YP_001723991.1 CDS hycI NC_010468.1 1081019 1081489 D involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 1081019..1081489 Escherichia coli ATCC 8739 6067730 YP_001723992.1 CDS EcolC_0996 NC_010468.1 1081648 1083072 R PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_2860 6-phospho-beta-glucosidase, cryptic; cryptic 6-phospho-beta-glucosidase complement(1081648..1083072) Escherichia coli ATCC 8739 6067726 YP_001723993.1 CDS EcolC_0997 NC_010468.1 1083081 1084538 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC complement(1083081..1084538) Escherichia coli ATCC 8739 6067723 YP_001723994.1 CDS EcolC_0998 NC_010468.1 1084795 1085808 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ssn:SSON_2858 ascBF operon repressor; LacI family transcriptional regulator 1084795..1085808 Escherichia coli ATCC 8739 6067720 YP_001723995.1 CDS EcolC_0999 NC_010468.1 1085957 1086484 D involved in electron transport from formate to hydrogen; electron transport protein HydN 1085957..1086484 Escherichia coli ATCC 8739 6067711 YP_001723996.1 CDS EcolC_1000 NC_010468.1 1086637 1088889 D TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: ssn:SSON_2856 transcriptional regulatory protein; (NiFe) hydrogenase maturation protein HypF 1086637..1088889 Escherichia coli ATCC 8739 6067708 YP_001723997.1 CDS EcolC_1001 NC_010468.1 1089017 1090150 R catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase complement(1089017..1090150) Escherichia coli ATCC 8739 6067699 YP_001723998.1 CDS EcolC_1002 NC_010468.1 1090147 1091586 R detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin complement(1090147..1091586) Escherichia coli ATCC 8739 6067674 YP_001723999.1 CDS EcolC_1003 NC_010468.1 1091773 1093287 D Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 1091773..1093287 Escherichia coli ATCC 8739 6067653 YP_001724000.1 CDS gutQ NC_010468.1 1093284 1094249 R catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase complement(1093284..1094249) Escherichia coli ATCC 8739 6067627 YP_001724001.1 CDS srlR NC_010468.1 1094242 1095015 R regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR complement(1094242..1095015) Escherichia coli ATCC 8739 6067617 YP_001724002.1 CDS EcolC_1006 NC_010468.1 1095082 1095441 R regulator for glucitol utilization; DNA-binding transcriptional activator GutM complement(1095082..1095441) Escherichia coli ATCC 8739 6067588 YP_001724003.1 CDS EcolC_1007 NC_010468.1 1095547 1096326 R catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase complement(1095547..1096326) Escherichia coli ATCC 8739 6067579 YP_001724004.1 CDS EcolC_1008 NC_010468.1 1096330 1096701 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA complement(1096330..1096701) Escherichia coli ATCC 8739 6067546 YP_001724005.1 CDS EcolC_1009 NC_010468.1 1096712 1097671 R KEGG: sbo:SBO_2815 PTS system glucitol/sorbitol-specific IIB component and second of two IIC components; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein; PTS system glucitol/sorbitol-specific transporter subunit IIBC complement(1096712..1097671) Escherichia coli ATCC 8739 6067534 YP_001724006.1 CDS EcolC_1010 NC_010468.1 1097668 1098231 R TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: sdy:SDY_2898 PTS system, glucitol/sorbitol-specific IIC component; PTS system glucitol/sorbitol-specific transporter subunit IIC complement(1097668..1098231) Escherichia coli ATCC 8739 6067520 YP_001724007.1 CDS EcolC_1011 NC_010468.1 1098487 1099572 D membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 1098487..1099572 Escherichia coli ATCC 8739 6067506 YP_001724008.1 CDS EcolC_1012 NC_010468.1 1099717 1100214 D PFAM: CinA domain protein; KEGG: ssn:SSON_2844 hypothetical protein; competence damage-inducible protein A 1099717..1100214 Escherichia coli ATCC 8739 6067461 YP_001724009.1 CDS recA NC_010468.1 1100294 1101355 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1100294..1101355 Escherichia coli ATCC 8739 6067411 YP_001724010.1 CDS recX NC_010468.1 1101424 1101924 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1101424..1101924 Escherichia coli ATCC 8739 6067382 YP_001724011.1 CDS alaS NC_010468.1 1102052 1104682 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1102052..1104682 Escherichia coli ATCC 8739 6067350 YP_001724012.1 CDS EcolC_1016 NC_010468.1 1104917 1105102 D affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 1104917..1105102 Escherichia coli ATCC 8739 6067339 YP_001724013.1 CDS EcolC_1017 NC_010468.1 1106560 1107126 D YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 1106560..1107126 Escherichia coli ATCC 8739 6067008 YP_001724014.1 CDS EcolC_1018 NC_010468.1 1107123 1107551 D KEGG: sfv:SFV_2815 hypothetical protein; hypothetical protein 1107123..1107551 Escherichia coli ATCC 8739 6066952 YP_001724015.1 CDS EcolC_1019 NC_010468.1 1107624 1109180 D involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 1107624..1109180 Escherichia coli ATCC 8739 6066930 YP_001724016.1 CDS EcolC_1020 NC_010468.1 1109330 1109845 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1109330..1109845 Escherichia coli ATCC 8739 6066897 YP_001724017.1 CDS EcolC_1021 NC_010468.1 1109909 1111447 R TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2830 probably membrane translocase; EmrB/QacA family drug resistance transporter complement(1109909..1111447) Escherichia coli ATCC 8739 6066876 YP_001724018.1 CDS EcolC_1022 NC_010468.1 1111464 1112636 R TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_2832 multidrug resistance secretion protein; efflux pump membrane protein complement(1111464..1112636) Escherichia coli ATCC 8739 6066872 YP_001724019.1 CDS EcolC_1023 NC_010468.1 1112763 1113293 R DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA complement(1112763..1113293) Escherichia coli ATCC 8739 6066837 YP_001724020.1 CDS EcolC_1024 NC_010468.1 1113384 1113719 R KEGG: sbo:SBO_2834 hypothetical protein; hypothetical protein complement(1113384..1113719) Escherichia coli ATCC 8739 6066835 YP_001724021.1 CDS EcolC_1025 NC_010468.1 1113709 1114446 R PFAM: AzlC family protein; KEGG: ssn:SSON_2826 hypothetical protein; AzlC family protein complement(1113709..1114446) Escherichia coli ATCC 8739 6066785 YP_001724022.1 CDS EcolC_1026 NC_010468.1 1114570 1115754 R PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2836 permease; major facilitator transporter complement(1114570..1115754) Escherichia coli ATCC 8739 6066756 YP_001724023.1 CDS proX NC_010468.1 1116046 1117038 R with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit complement(1116046..1117038) Escherichia coli ATCC 8739 6066751 YP_001724024.1 CDS EcolC_1028 NC_010468.1 1117096 1118160 R with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein complement(1117096..1118160) Escherichia coli ATCC 8739 6066745 YP_001724025.1 CDS EcolC_1029 NC_010468.1 1118153 1119355 R with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit complement(1118153..1119355) Escherichia coli ATCC 8739 6066741 YP_001724026.1 CDS nrdF NC_010468.1 1119709 1120668 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(1119709..1120668) Escherichia coli ATCC 8739 6066736 YP_001724027.1 CDS EcolC_1031 NC_010468.1 1120678 1122783 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1120678..1122783) Escherichia coli ATCC 8739 6066721 YP_001724028.1 CDS nrdI NC_010468.1 1122795 1123205 R in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein complement(1122795..1123205) Escherichia coli ATCC 8739 6066667 YP_001724029.1 CDS EcolC_1033 NC_010468.1 1123202 1123447 R TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: sbo:SBO_2844 glutaredoxin-like protein; glutaredoxin-like protein complement(1123202..1123447) Escherichia coli ATCC 8739 6066650 YP_001724030.1 CDS EcolC_1034 NC_010468.1 1123695 1124024 R PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2863 hypothetical protein; hypothetical protein complement(1123695..1124024) Escherichia coli ATCC 8739 6066640 YP_001724031.1 CDS EcolC_1035 NC_010468.1 1124176 1124520 D KEGG: sbo:SBO_2848 hypothetical protein; hypothetical protein 1124176..1124520 Escherichia coli ATCC 8739 6066624 YP_001724032.1 CDS EcolC_1036 NC_010468.1 1124557 1125006 R PFAM: protein of unknown function DUF1144; KEGG: sbo:SBO_2849 hypothetical protein; hypothetical protein complement(1124557..1125006) Escherichia coli ATCC 8739 6066617 YP_001724033.1 CDS EcolC_1037 NC_010468.1 1125675 1126079 D PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sdy:SDY_2859 DNA-binding protein; nucleoid-associated DNA binding protein 1125675..1126079 Escherichia coli ATCC 8739 6066601 YP_001724034.1 CDS EcolC_1038 NC_010468.1 1126126 1126650 R SMART: Rhodanese domain protein; KEGG: ssn:SSON_2812 hypothetical protein; rhodanese domain-containing protein complement(1126126..1126650) Escherichia coli ATCC 8739 6066574 YP_001724035.1 CDS EcolC_1039 NC_010468.1 1126660 1126959 R PFAM: regulatory protein ArsR; KEGG: sbo:SBO_2852 hypothetical protein; ArsR family transcriptional regulator complement(1126660..1126959) Escherichia coli ATCC 8739 6066533 YP_001724036.1 CDS EcolC_1040 NC_010468.1 1127142 1127300 D PFAM: protein of unknown function UPF0057; KEGG: sdy:SDY_2856 hypothetical protein; hypothetical protein 1127142..1127300 Escherichia coli ATCC 8739 6066508 YP_001724037.1 CDS EcolC_1041 NC_010468.1 1127384 1127833 D PFAM: Peptidoglycan-binding LysM; transport-associated; SMART: Transport-associated and nodulation region; KEGG: sdy:SDY_2855 hypothetical protein; LysM domain/BON superfamily protein 1127384..1127833 Escherichia coli ATCC 8739 6066492 YP_001724038.1 CDS EcolC_1042 NC_010468.1 1127834 1128496 R regulator of gab gene expression; DNA-binding transcriptional regulator CsiR complement(1127834..1128496) Escherichia coli ATCC 8739 6066486 YP_001724039.1 CDS EcolC_1043 NC_010468.1 1128517 1129917 R TIGRFAM: GABA permease; PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2853 transport permease protein of gamma-aminobutyrate; gamma-aminobutyrate transporter complement(1128517..1129917) Escherichia coli ATCC 8739 6066479 YP_001724040.1 CDS EcolC_1044 NC_010468.1 1130155 1131435 R catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase complement(1130155..1131435) Escherichia coli ATCC 8739 6066436 YP_001724041.1 CDS gabD NC_010468.1 1131449 1132897 R catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I complement(1131449..1132897) Escherichia coli ATCC 8739 6066422 YP_001724042.1 CDS EcolC_1046 NC_010468.1 1132920 1134188 R catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase complement(1132920..1134188) Escherichia coli ATCC 8739 6066419 YP_001724043.1 CDS EcolC_1047 NC_010468.1 1134207 1135184 R in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein complement(1134207..1135184) Escherichia coli ATCC 8739 6066405 YP_001724044.1 CDS EcolC_1048 NC_010468.1 1135932 1137773 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: sfv:SFV_2845 putative enzyme; alpha amylase complement(1135932..1137773) Escherichia coli ATCC 8739 6066394 YP_001724045.1 CDS EcolC_1051 NC_010468.1 1140960 1141103 D KEGG: ssn:SSON_2797 hypothetical protein; hypothetical protein 1140960..1141103 Escherichia coli ATCC 8739 6066305 YP_001724046.1 CDS EcolC_1052 NC_010468.1 1141442 1146022 D TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sdy:SDY_1204 putative ATP-binding component of a transport system; outer membrane autotransporter 1141442..1146022 Escherichia coli ATCC 8739 6066296 YP_001724047.1 CDS EcolC_1053 NC_010468.1 1146686 1149019 R KEGG: stt:t2656 hypothetical protein; TIGRFAM: phage/plasmid primase, P4 family; PFAM: D5 protein; TOPRIM domain protein; P4 alpha zinc-binding domain protein; primase P4; SMART: Toprim sub domain protein; P4 family phage/plasmid primase complement(1146686..1149019) Escherichia coli ATCC 8739 6066280 YP_001724048.1 CDS EcolC_1054 NC_010468.1 1149034 1149354 R KEGG: sbo:SBO_4166 putative protein encoded in prophage; putative prophage protein complement(1149034..1149354) Escherichia coli ATCC 8739 6066265 YP_001724049.1 CDS EcolC_1055 NC_010468.1 1149490 1149945 R KEGG: stt:t2654 hypothetical protein; hypothetical protein complement(1149490..1149945) Escherichia coli ATCC 8739 6066258 YP_001724050.1 CDS EcolC_1056 NC_010468.1 1149938 1150225 R KEGG: stt:t2653 hypothetical protein; hypothetical protein complement(1149938..1150225) Escherichia coli ATCC 8739 6066200 YP_001724051.1 CDS EcolC_1057 NC_010468.1 1150218 1150808 R KEGG: sbo:SBO_4168 putative bacteriophage protein; putative bacteriophage protein complement(1150218..1150808) Escherichia coli ATCC 8739 6066125 YP_001724052.1 CDS EcolC_1058 NC_010468.1 1150805 1151071 R PFAM: Prophage CP4-57 regulatory; KEGG: sbo:SBO_4169 hypothetical protein; phage transcriptional regulator, AlpA complement(1150805..1151071) Escherichia coli ATCC 8739 6066109 YP_001724053.1 CDS EcolC_1059 NC_010468.1 1151623 1152357 D KEGG: sbo:SBO_4170 hypothetical protein; hypothetical protein 1151623..1152357 Escherichia coli ATCC 8739 6066106 YP_001724054.1 CDS EcolC_1060 NC_010468.1 1152354 1152854 D PFAM: transcriptional activator Ogr/delta; KEGG: stt:t2649 hypothetical protein; transcriptional activator Ogr/delta 1152354..1152854 Escherichia coli ATCC 8739 6066093 YP_001724055.1 CDS EcolC_1061 NC_010468.1 1152928 1153500 D PFAM: polarity suppression protein; KEGG: stt:t2648 hypothetical protein; polarity suppression protein 1152928..1153500 Escherichia coli ATCC 8739 6066090 YP_001724056.1 CDS EcolC_1062 NC_010468.1 1153980 1155683 D hypothetical protein 1153980..1155683 Escherichia coli ATCC 8739 6066076 YP_001724057.1 CDS EcolC_1063 NC_010468.1 1155680 1156876 R PFAM: integrase family protein; KEGG: esa:ESA_00630 hypothetical protein; integrase family protein complement(1155680..1156876) Escherichia coli ATCC 8739 6066036 YP_001724058.1 CDS smpB NC_010468.1 1157638 1158120 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1157638..1158120) Escherichia coli ATCC 8739 6065996 YP_001724059.1 CDS EcolC_1065 NC_010468.1 1158252 1158728 D PFAM: cyclase/dehydrase; KEGG: sdy:SDY_2792 hypothetical protein; hypothetical protein 1158252..1158728 Escherichia coli ATCC 8739 6065964 YP_001724060.1 CDS EcolC_1066 NC_010468.1 1158718 1159008 D PFAM: protein of unknown function UPF0125; KEGG: sbo:SBO_2753 hypothetical protein; hypothetical protein 1158718..1159008 Escherichia coli ATCC 8739 6065916 YP_001724061.1 CDS EcolC_1067 NC_010468.1 1159070 1159411 R PFAM: SmpA/OmlA domain protein; KEGG: cko:CKO_03939 hypothetical protein; hypothetical protein complement(1159070..1159411) Escherichia coli ATCC 8739 6065903 YP_001724062.1 CDS EcolC_1068 NC_010468.1 1159560 1161221 R TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: ssn:SSON_2772 protein used in recombination and DNA repair; recombination and repair protein complement(1159560..1161221) Escherichia coli ATCC 8739 6065877 YP_001724063.1 CDS ppnK NC_010468.1 1161307 1162185 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(1161307..1162185) Escherichia coli ATCC 8739 6065837 YP_001724064.1 CDS EcolC_1070 NC_010468.1 1162308 1162901 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1162308..1162901 Escherichia coli ATCC 8739 6065816 YP_001724065.1 CDS EcolC_1071 NC_010468.1 1162956 1164197 R PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: ssn:SSON_2769 uncharacterized CBS domain-containing protein; hypothetical protein complement(1162956..1164197) Escherichia coli ATCC 8739 6065788 YP_001724066.1 CDS EcolC_1072 NC_010468.1 1164263 1165129 R PFAM: cytochrome c assembly protein; KEGG: sdy:SDY_2785 hypothetical protein; cytochrome c assembly protein complement(1164263..1165129) Escherichia coli ATCC 8739 6065767 YP_001724067.1 CDS EcolC_1073 NC_010468.1 1165221 1166582 D with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 1165221..1166582 Escherichia coli ATCC 8739 6065703 YP_001724068.1 CDS rpsP NC_010468.1 1166719 1166967 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1166719..1166967 Escherichia coli ATCC 8739 6065667 YP_001724069.1 CDS rimM NC_010468.1 1166986 1167534 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1166986..1167534 Escherichia coli ATCC 8739 6065653 YP_001724070.1 CDS trmD NC_010468.1 1167565 1168332 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1167565..1168332 Escherichia coli ATCC 8739 6065648 YP_001724071.1 CDS rplS NC_010468.1 1168374 1168721 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1168374..1168721 Escherichia coli ATCC 8739 6065606 YP_001724072.1 CDS EcolC_1078 NC_010468.1 1168797 1169279 R PFAM: OmpA/MotB domain protein; KEGG: sbo:SBO_2741 putative outer membrane protein; putative outer membrane lipoprotein complement(1168797..1169279) Escherichia coli ATCC 8739 6065579 YP_001724073.1 CDS EcolC_1079 NC_010468.1 1169295 1170521 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_2761 hypothetical protein; hypothetical protein complement(1169295..1170521) Escherichia coli ATCC 8739 6065565 YP_001724074.1 CDS EcolC_1080 NC_010468.1 1170511 1171029 R KEGG: ssn:SSON_2755 hypothetical protein; hypothetical protein complement(1170511..1171029) Escherichia coli ATCC 8739 6065557 YP_001724075.1 CDS EcolC_1081 NC_010468.1 1171179 1171544 R KEGG: sfv:SFV_2869 hypothetical protein; hypothetical protein complement(1171179..1171544) Escherichia coli ATCC 8739 6065553 YP_001724076.1 CDS EcolC_1082 NC_010468.1 1171754 1172824 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1171754..1172824 Escherichia coli ATCC 8739 6065529 YP_001724077.1 CDS tyrA NC_010468.1 1172835 1173956 D catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 1172835..1173956 Escherichia coli ATCC 8739 6065511 YP_001724078.1 CDS pheA NC_010468.1 1173999 1175159 R catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase complement(1173999..1175159) Escherichia coli ATCC 8739 6065490 YP_001724079.1 CDS EcolC_1085 NC_010468.1 1175408 1175758 R associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA complement(1175408..1175758) Escherichia coli ATCC 8739 6065488 YP_001724080.1 CDS EcolC_1086 NC_010468.1 1176029 1176766 R with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO complement(1176029..1176766) Escherichia coli ATCC 8739 6065472 YP_001724081.1 CDS rluD NC_010468.1 1176901 1177881 D responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 1176901..1177881 Escherichia coli ATCC 8739 6065468 YP_001724082.1 CDS EcolC_1088 NC_010468.1 1177878 1178609 D PFAM: protein of unknown function DUF152; KEGG: sdy:SDY_2836 hypothetical protein; hypothetical protein 1177878..1178609 Escherichia coli ATCC 8739 6065374 YP_001724083.1 CDS EcolC_1089 NC_010468.1 1178739 1181312 D KEGG: sbo:SBO_2627 heat shock protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; protein disaggregation chaperone 1178739..1181312 Escherichia coli ATCC 8739 6065349 YP_001724084.1 CDS EcolC_1090 NC_010468.1 1187176 1188474 D TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2830 alpha-ketoglutarate permease; alpha-ketoglutarate transporter 1187176..1188474 Escherichia coli ATCC 8739 6066567 YP_001724085.1 CDS EcolC_1091 NC_010468.1 1188471 1188794 R KEGG: sfv:SFV_2649 hypothetical protein; hypothetical protein complement(1188471..1188794) Escherichia coli ATCC 8739 6066409 YP_001724086.1 CDS pssA NC_010468.1 1188840 1190195 R catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase complement(1188840..1190195) Escherichia coli ATCC 8739 6066313 YP_001724087.1 CDS EcolC_1093 NC_010468.1 1190309 1192969 R PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: sbo:SBO_2616 hypothetical protein; N-acetyltransferase GCN5 complement(1190309..1192969) Escherichia coli ATCC 8739 6065932 YP_001724088.1 CDS EcolC_1094 NC_010468.1 1193001 1193699 R PFAM: DTW domain containing protein; KEGG: sdy:SDY_2826 hypothetical protein; DTW domain-containing protein complement(1193001..1193699) Escherichia coli ATCC 8739 6065073 YP_001724089.1 CDS EcolC_1095 NC_010468.1 1193768 1194187 R TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sdy:SDY_2825 putative thioredoxin-like protein; thioredoxin 2 complement(1193768..1194187) Escherichia coli ATCC 8739 6065929 YP_001724090.1 CDS EcolC_1096 NC_010468.1 1194394 1195431 D PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sdy:SDY_2824 hypothetical protein; putative methyltransferase 1194394..1195431 Escherichia coli ATCC 8739 6064688 YP_001724091.1 CDS EcolC_1097 NC_010468.1 1195479 1196168 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1195479..1196168) Escherichia coli ATCC 8739 6066177 YP_001724092.1 CDS EcolC_1098 NC_010468.1 1196473 1196856 D stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 1196473..1196856 Escherichia coli ATCC 8739 6064849 YP_001724093.1 CDS EcolC_1099 NC_010468.1 1196912 1197499 R PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ssn:SSON_2704 hypothetical protein; neutral amino-acid efflux protein complement(1196912..1197499) Escherichia coli ATCC 8739 6064988 YP_001724094.1 CDS EcolC_1100 NC_010468.1 1197603 1198484 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_2703 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 1197603..1198484 Escherichia coli ATCC 8739 6065620 YP_001724095.1 CDS EcolC_1101 NC_010468.1 1198693 1200027 R facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB complement(1198693..1200027) Escherichia coli ATCC 8739 6067359 YP_001724096.1 CDS EcolC_1102 NC_010468.1 1200159 1200896 D PFAM: methyltransferase small; KEGG: sfv:SFV_2638 putative enzyme; methyltransferase small 1200159..1200896 Escherichia coli ATCC 8739 6065235 YP_001724097.1 CDS EcolC_1103 NC_010468.1 1200881 1202503 R catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase complement(1200881..1202503) Escherichia coli ATCC 8739 6065232 YP_001724098.1 CDS EcolC_1104 NC_010468.1 1202911 1203486 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 1202911..1203486 Escherichia coli ATCC 8739 6065230 YP_001724099.1 CDS EcolC_1105 NC_010468.1 1203519 1204169 D PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: sdy:SDY_2813 sigma-E factor, negative regulatory protein; anti-RNA polymerase sigma factor SigE 1203519..1204169 Escherichia coli ATCC 8739 6066184 YP_001724100.1 CDS rseB NC_010468.1 1204169 1205125 D periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 1204169..1205125 Escherichia coli ATCC 8739 6066707 YP_001724101.1 CDS EcolC_1107 NC_010468.1 1205122 1205601 D involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 1205122..1205601 Escherichia coli ATCC 8739 6065017 YP_001724102.1 CDS EcolC_1108 NC_010468.1 1205799 1207598 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1205799..1207598 Escherichia coli ATCC 8739 6066887 YP_001724103.1 CDS EcolC_1109 NC_010468.1 1207614 1208588 D catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 1207614..1208588 Escherichia coli ATCC 8739 6067912 YP_001724104.1 CDS rnc NC_010468.1 1208860 1209540 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1208860..1209540 Escherichia coli ATCC 8739 6065398 YP_001724105.1 CDS era NC_010468.1 1209537 1210442 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1209537..1210442 Escherichia coli ATCC 8739 6066524 YP_001724106.1 CDS recO NC_010468.1 1210454 1211182 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1210454..1211182 Escherichia coli ATCC 8739 6067917 YP_001724107.1 CDS EcolC_1113 NC_010468.1 1211194 1211925 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1211194..1211925 Escherichia coli ATCC 8739 6067933 YP_001724108.1 CDS acpS NC_010468.1 1211925 1212305 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1211925..1212305 Escherichia coli ATCC 8739 6067937 YP_001724109.1 CDS EcolC_1115 NC_010468.1 1213000 1213260 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_2590 hypothetical protein; 4Fe-4S ferredoxin complement(1213000..1213260) Escherichia coli ATCC 8739 6065203 YP_001724110.1 CDS EcolC_1116 NC_010468.1 1213316 1214164 R PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sbo:SBO_2589 hypothetical protein; putative DNA-binding transcriptional regulator complement(1213316..1214164) Escherichia coli ATCC 8739 6067947 YP_001724111.1 CDS EcolC_1117 NC_010468.1 1214373 1215008 D TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: sfv:SFV_2608 hypothetical protein; hypothetical protein 1214373..1215008 Escherichia coli ATCC 8739 6067958 YP_001724112.1 CDS EcolC_1118 NC_010468.1 1215066 1215569 D PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sbo:SBO_2587 putative deaminase; tRNA-specific adenosine deaminase 1215066..1215569 Escherichia coli ATCC 8739 6067970 YP_001724113.1 CDS EcolC_1119 NC_010468.1 1215566 1217122 R YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase complement(1215566..1217122) Escherichia coli ATCC 8739 6067971 YP_001724114.1 CDS EcolC_1120 NC_010468.1 1217380 1221267 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 1217380..1221267 Escherichia coli ATCC 8739 6067973 YP_001724115.1 CDS EcolC_1121 NC_010468.1 1221825 1223252 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_2746 putative 2-component sensor protein; integral membrane sensor signal transduction histidine kinase 1221825..1223252 Escherichia coli ATCC 8739 6067978 YP_001724116.1 CDS EcolC_1122 NC_010468.1 1223417 1224130 D KEGG: sfv:SFV_2603 putative alpha helix protein; hypothetical protein 1223417..1224130 Escherichia coli ATCC 8739 6067981 YP_001724117.1 CDS EcolC_1123 NC_010468.1 1224120 1225454 D PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sbo:SBO_2582 putative 2-component transcriptional regulator; two component sigma-54 specific Fis family transcriptional regulator 1224120..1225454 Escherichia coli ATCC 8739 6067969 YP_001724118.1 CDS EcolC_1124 NC_010468.1 1225515 1225853 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 1225515..1225853 Escherichia coli ATCC 8739 6067988 YP_001724119.1 CDS EcolC_1125 NC_010468.1 1225898 1227088 R flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase complement(1225898..1227088) Escherichia coli ATCC 8739 6067991 YP_001724120.1 CDS glyA NC_010468.1 1227416 1228669 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1227416..1228669 Escherichia coli ATCC 8739 6067996 YP_001724121.1 CDS EcolC_1127 NC_010468.1 1228867 1230060 R PFAM: ROK family protein; KEGG: sbo:SBO_2578 putative NAGC-like transcriptional regulator; ROK family protein complement(1228867..1230060) Escherichia coli ATCC 8739 6068004 YP_001724122.1 CDS EcolC_1128 NC_010468.1 1230178 1233459 D PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sbo:SBO_2577 hypothetical protein; hypothetical protein 1230178..1233459 Escherichia coli ATCC 8739 6068006 YP_001724123.1 CDS EcolC_1129 NC_010468.1 1233556 1234539 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sfv:SFV_2596 putative LacI-type transcriptional regulator; periplasmic binding protein/LacI transcriptional regulator 1233556..1234539 Escherichia coli ATCC 8739 6068007 YP_001724124.1 CDS EcolC_1130 NC_010468.1 1234562 1236073 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_2573 putative ATP-binding component of a transport system; ABC transporter-like protein 1234562..1236073 Escherichia coli ATCC 8739 6068018 YP_001724125.1 CDS EcolC_1131 NC_010468.1 1236098 1237096 D PFAM: inner-membrane translocator; KEGG: ssn:SSON_2629 putative transport system permease protein; monosaccharide-transporting ATPase 1236098..1237096 Escherichia coli ATCC 8739 6068023 YP_001724126.1 CDS EcolC_1132 NC_010468.1 1237162 1238223 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_2628 putative oxidoreductase; alcohol dehydrogenase 1237162..1238223 Escherichia coli ATCC 8739 6068026 YP_001724127.1 CDS EcolC_1133 NC_010468.1 1238235 1239107 D PFAM: Aldose 1-epimerase; KEGG: ssn:SSON_2627 hypothetical protein; aldose 1-epimerase 1238235..1239107 Escherichia coli ATCC 8739 6067993 YP_001724128.1 CDS EcolC_1134 NC_010468.1 1239155 1239577 R PFAM: DoxX family protein; KEGG: sfx:S2762 hypothetical protein; DoxX family protein complement(1239155..1239577) Escherichia coli ATCC 8739 6068028 YP_001724129.1 CDS EcolC_1135 NC_010468.1 1239674 1240876 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2624 ferredoxin reductase subunit of phenylpropionate dioxygenase; phenylpropionate dioxygenase ferredoxin reductase subunit complement(1239674..1240876) Escherichia coli ATCC 8739 6068037 YP_001724130.1 CDS EcolC_1136 NC_010468.1 1240886 1241698 R Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase complement(1240886..1241698) Escherichia coli ATCC 8739 6068039 YP_001724131.1 CDS EcolC_1137 NC_010468.1 1241695 1242015 R PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_2622 ferredoxin subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase ferredoxin subunit complement(1241695..1242015) Escherichia coli ATCC 8739 6068043 YP_001724132.1 CDS EcolC_1138 NC_010468.1 1242015 1242533 R PFAM: aromatic-ring-hydroxylating dioxygenase beta subunit; KEGG: sfx:S2758 small terminal subunit of phenylpropionate dioxygenase; 3-phenylpropionate dioxygenase subunit beta complement(1242015..1242533) Escherichia coli ATCC 8739 6067174 YP_001724133.1 CDS EcolC_1139 NC_010468.1 1242530 1243891 R PFAM: Rieske [2Fe-2S] domain protein; Aromatic-ring-hydroxylating dioxygenase, alpha subunit-like; KEGG: ssn:SSON_2620 large terminal subunit of phenylpropionate dioxygenase; aromatic-ring-hydroxylating dioxygenase subunit alpha-like protein complement(1242530..1243891) Escherichia coli ATCC 8739 6068044 YP_001724134.1 CDS EcolC_1140 NC_010468.1 1244027 1244917 D activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 1244027..1244917 Escherichia coli ATCC 8739 6068050 YP_001724135.1 CDS EcolC_1141 NC_010468.1 1245077 1246216 D putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 1245077..1246216 Escherichia coli ATCC 8739 6068051 YP_001724136.1 CDS EcolC_1142 NC_010468.1 1246208 1247488 R PFAM: PRD domain protein; KEGG: sbo:SBO_2559 hypothetical protein; stationary phase inducible protein CsiE complement(1246208..1247488) Escherichia coli ATCC 8739 6068053 YP_001724137.1 CDS EcolC_1143 NC_010468.1 1247679 1248533 R KEGG: sdy:SDY_2730 putative enzyme; putative enzyme complement(1247679..1248533) Escherichia coli ATCC 8739 6068054 YP_001724138.1 CDS EcolC_1144 NC_010468.1 1248678 1249481 R PFAM: inositol monophosphatase; KEGG: sbo:SBO_2557 SuhB; inositol monophosphatase complement(1248678..1249481) Escherichia coli ATCC 8739 6067927 YP_001724139.1 CDS EcolC_1145 NC_010468.1 1249600 1250340 D TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sbo:SBO_2556 putative ATP synthase beta subunit; RNA methyltransferase 1249600..1250340 Escherichia coli ATCC 8739 6065229 YP_001724140.1 CDS EcolC_1146 NC_010468.1 1250610 1251098 D regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 1250610..1251098 Escherichia coli ATCC 8739 6065655 YP_001724141.1 CDS EcolC_1147 NC_010468.1 1251339 1252553 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 1251339..1252553 Escherichia coli ATCC 8739 6068059 YP_001724142.1 CDS EcolC_1148 NC_010468.1 1252581 1252967 D TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: sdy:SDY_2725 hypothetical protein; scaffold protein 1252581..1252967 Escherichia coli ATCC 8739 6068060 YP_001724143.1 CDS iscA NC_010468.1 1252984 1253307 D forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 1252984..1253307 Escherichia coli ATCC 8739 6068062 YP_001724144.1 CDS hscB NC_010468.1 1253403 1253918 D J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 1253403..1253918 Escherichia coli ATCC 8739 6068065 YP_001724145.1 CDS hscA NC_010468.1 1253935 1255785 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 1253935..1255785 Escherichia coli ATCC 8739 6068069 YP_001724146.1 CDS EcolC_1152 NC_010468.1 1255787 1256122 D TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: sbo:SBO_2549 [2FE-2S] ferredoxin, electron carrer protein; 2Fe-2S ferredoxin 1255787..1256122 Escherichia coli ATCC 8739 6068057 YP_001724147.1 CDS EcolC_1153 NC_010468.1 1256134 1256334 D TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: sdy:SDY_2720 hypothetical protein; hypothetical protein 1256134..1256334 Escherichia coli ATCC 8739 6068076 YP_001724148.1 CDS EcolC_1154 NC_010468.1 1256392 1257675 D catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 1256392..1257675 Escherichia coli ATCC 8739 6068081 YP_001724149.1 CDS EcolC_1155 NC_010468.1 1257817 1258593 D enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 1257817..1258593 Escherichia coli ATCC 8739 6068084 YP_001724150.1 CDS sseA NC_010468.1 1259411 1260256 R catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase complement(1259411..1260256) Escherichia coli ATCC 8739 6068086 YP_001724151.1 CDS EcolC_1157 NC_010468.1 1260463 1265424 D PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: ssn:SSON_2602 hypothetical protein; alpha-2-macroglobulin domain-containing protein 1260463..1265424 Escherichia coli ATCC 8739 6068090 YP_001724152.1 CDS EcolC_1158 NC_010468.1 1265425 1267737 D penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 1265425..1267737 Escherichia coli ATCC 8739 6068092 YP_001724153.1 CDS ndk NC_010468.1 1267886 1268317 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1267886..1268317 Escherichia coli ATCC 8739 6068096 YP_001724154.1 CDS EcolC_1160 NC_010468.1 1268467 1269621 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1268467..1269621 Escherichia coli ATCC 8739 6068099 YP_001724155.1 CDS EcolC_1161 NC_010468.1 1269906 1270919 D PFAM: helix-turn-helix domain protein; KEGG: sdy:SDY_2712 hypothetical protein; cytoskeletal protein RodZ 1269906..1270919 Escherichia coli ATCC 8739 6068082 YP_001724156.1 CDS ispG NC_010468.1 1270946 1272064 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1270946..1272064 Escherichia coli ATCC 8739 6068100 YP_001724157.1 CDS hisS NC_010468.1 1272175 1273449 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1272175..1273449 Escherichia coli ATCC 8739 6068101 YP_001724158.1 CDS EcolC_1164 NC_010468.1 1273467 1274087 D KEGG: sdy:SDY_2709 hypothetical protein; hypothetical protein 1273467..1274087 Escherichia coli ATCC 8739 6068102 YP_001724159.1 CDS EcolC_1165 NC_010468.1 1274098 1275276 D with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 1274098..1275276 Escherichia coli ATCC 8739 6065489 YP_001724160.1 CDS engA NC_010468.1 1275394 1276866 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1275394..1276866 Escherichia coli ATCC 8739 6065502 YP_001724161.1 CDS EcolC_1167 NC_010468.1 1276935 1277150 D PFAM: protein of unknown function DUF1407; KEGG: sdy:SDY_2706 hypothetical protein; hypothetical protein 1276935..1277150 Escherichia coli ATCC 8739 6066301 YP_001724162.1 CDS xseA NC_010468.1 1277147 1278517 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1277147..1278517) Escherichia coli ATCC 8739 6066491 YP_001724163.1 CDS EcolC_1169 NC_010468.1 1278679 1280145 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 1278679..1280145 Escherichia coli ATCC 8739 6066644 YP_001724164.1 CDS guaA NC_010468.1 1280214 1281791 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1280214..1281791 Escherichia coli ATCC 8739 6067244 YP_001724165.1 CDS EcolC_1171 NC_010468.1 1281884 1282423 R KEGG: sdy:SDY_2702 hypothetical protein; hypothetical protein complement(1281884..1282423) Escherichia coli ATCC 8739 6064607 YP_001724166.1 CDS EcolC_1172 NC_010468.1 1282439 1282954 R PFAM: 17 kDa surface antigen; KEGG: ssn:SSON_2587 putative outer membrane lipoprotein; 17 kDa surface antigen complement(1282439..1282954) Escherichia coli ATCC 8739 6064878 YP_001724167.1 CDS EcolC_1173 NC_010468.1 1283811 1286054 D PFAM: EAL domain protein; MASE1 domain protein; SMART: GGDEF domain containing protein; KEGG: ssn:SSON_2585 putative cytochrome c-type biogenesis protein; diguanylate cyclase/phosphodiesterase 1283811..1286054 Escherichia coli ATCC 8739 6064994 YP_001724168.1 CDS EcolC_1174 NC_010468.1 1286093 1287634 R PFAM: Ppx/GppA phosphatase; KEGG: ssn:SSON_2584 exopolyphosphatase; exopolyphosphatase complement(1286093..1287634) Escherichia coli ATCC 8739 6065826 YP_001724169.1 CDS EcolC_1175 NC_010468.1 1287639 1289705 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(1287639..1289705) Escherichia coli ATCC 8739 6067151 YP_001724170.1 CDS purN NC_010468.1 1289876 1290514 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(1289876..1290514) Escherichia coli ATCC 8739 6066039 YP_001724171.1 CDS EcolC_1177 NC_010468.1 1290514 1291551 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(1290514..1291551) Escherichia coli ATCC 8739 6064917 YP_001724172.1 CDS upp NC_010468.1 1291876 1292502 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1291876..1292502 Escherichia coli ATCC 8739 6064905 YP_001724173.1 CDS EcolC_1179 NC_010468.1 1292588 1293877 D TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_2579 uracil transport; uracil transporter 1292588..1293877 Escherichia coli ATCC 8739 6064741 YP_001724174.1 CDS EcolC_1180 NC_010468.1 1293927 1294673 D controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 1293927..1294673 Escherichia coli ATCC 8739 6064680 YP_001724175.1 CDS EcolC_1181 NC_010468.1 1294811 1295170 R TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sdy:SDY_2684 putative oxidoreductase; arsenate reductase complement(1294811..1295170) Escherichia coli ATCC 8739 6067690 YP_001724176.1 CDS EcolC_1182 NC_010468.1 1295191 1296654 R PFAM: peptidase M48 Ste24p; KEGG: sfv:SFV_2539 hypothetical protein; peptidase M48 Ste24p complement(1295191..1296654) Escherichia coli ATCC 8739 6067344 YP_001724177.1 CDS EcolC_1183 NC_010468.1 1296867 1297928 D PFAM: protein of unknown function UPF0118; KEGG: sdy:SDY_2682 putative permease; hypothetical protein 1296867..1297928 Escherichia coli ATCC 8739 6066923 YP_001724178.1 CDS focB NC_010468.1 1297966 1298814 R inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter complement(1297966..1298814) Escherichia coli ATCC 8739 6066900 YP_001724179.1 CDS EcolC_1185 NC_010468.1 1298836 1300848 R PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_2572 putative 2-component regulator, interaction with sigma 54; NifA subfamily transcriptional regulator complement(1298836..1300848) Escherichia coli ATCC 8739 6066794 YP_001724180.1 CDS EcolC_1186 NC_010468.1 1300878 1301291 R PFAM: formate hydrogenlyase maturation HycH; KEGG: ssn:SSON_2571 putative protein processing element; formate hydrogenlyase maturation HycH complement(1300878..1301291) Escherichia coli ATCC 8739 6066154 YP_001724181.1 CDS EcolC_1187 NC_010468.1 1301284 1302042 R PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ssn:SSON_2570 hydrogenase 4 Fe-S subunit; NADH ubiquinone oxidoreductase 20 kDa subunit complement(1301284..1302042) Escherichia coli ATCC 8739 6065393 YP_001724182.1 CDS EcolC_1188 NC_010468.1 1302039 1302578 R probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H complement(1302039..1302578) Escherichia coli ATCC 8739 6066219 YP_001724183.1 CDS EcolC_1189 NC_010468.1 1302588 1304255 R PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: ssn:SSON_2568 hydrogenase 4 subunit; NADH dehydrogenase (ubiquinone) 30 kDa subunit complement(1302588..1304255) Escherichia coli ATCC 8739 6066315 YP_001724184.1 CDS EcolC_1190 NC_010468.1 1304245 1305825 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2567 hydrogenase 4 membrane subunit; hydrogenase 4 subunit F complement(1304245..1305825) Escherichia coli ATCC 8739 6065804 YP_001724185.1 CDS hyfE NC_010468.1 1305830 1306480 R interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit complement(1305830..1306480) Escherichia coli ATCC 8739 6065673 YP_001724186.1 CDS EcolC_1192 NC_010468.1 1306492 1307844 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: sfv:SFV_2529 hydrogenase 4 membrane subunit; hydrogenase 4 subunit D complement(1306492..1307844) Escherichia coli ATCC 8739 6065531 YP_001724187.1 CDS EcolC_1194 NC_010468.1 1308904 1310922 R PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2563 hydrogenase 4 membrane subunit; hydrogenase 4 subunit B complement(1308904..1310922) Escherichia coli ATCC 8739 6065193 YP_001724188.1 CDS EcolC_1195 NC_010468.1 1310922 1311539 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2526 hydrogenase 4 Fe-S subunit; 4Fe-4S ferredoxin complement(1310922..1311539) Escherichia coli ATCC 8739 6065028 YP_001724189.1 CDS bcp NC_010468.1 1311792 1312262 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(1311792..1312262) Escherichia coli ATCC 8739 6064853 YP_001724190.1 CDS gcvR NC_010468.1 1312262 1312834 R negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor complement(1312262..1312834) Escherichia coli ATCC 8739 6064771 YP_001724191.1 CDS EcolC_1198 NC_010468.1 1312980 1313858 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1312980..1313858 Escherichia coli ATCC 8739 6064663 YP_001724192.1 CDS EcolC_1199 NC_010468.1 1313875 1314909 D PFAM: NlpBDapX family lipoprotein; KEGG: ssn:SSON_2558 lipoprotein-34; lipoprotein 1313875..1314909 Escherichia coli ATCC 8739 6067645 YP_001724193.1 CDS EcolC_1200 NC_010468.1 1315122 1315835 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1315122..1315835 Escherichia coli ATCC 8739 6067661 YP_001724194.1 CDS EcolC_1201 NC_010468.1 1316003 1316866 D PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: sfv:SFV_2520 hypothetical protein; hypothetical protein 1316003..1316866 Escherichia coli ATCC 8739 6065224 YP_001724195.1 CDS EcolC_1202 NC_010468.1 1316881 1318896 D PFAM: GCN5-related N-acetyltransferase; protein of unknown function DUF699 ATPase putative; KEGG: ssn:SSON_2555 hypothetical protein; hypothetical protein 1316881..1318896 Escherichia coli ATCC 8739 6067451 YP_001724196.1 CDS EcolC_1203 NC_010468.1 1318970 1319668 D Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 1318970..1319668 Escherichia coli ATCC 8739 6067470 YP_001724197.1 CDS EcolC_1204 NC_010468.1 1319778 1319978 R KEGG: sdy:SDY_2657 hypothetical protein; hypothetical protein complement(1319778..1319978) Escherichia coli ATCC 8739 6067112 YP_001724198.1 CDS EcolC_1205 NC_010468.1 1320006 1321133 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(1320006..1321133) Escherichia coli ATCC 8739 6067161 YP_001724199.1 CDS EcolC_1206 NC_010468.1 1321137 1321493 R PFAM: arsenate reductase and related; KEGG: sdy:SDY_2655 hypothetical protein; hypothetical protein complement(1321137..1321493) Escherichia coli ATCC 8739 6067526 YP_001724200.1 CDS EcolC_1207 NC_010468.1 1322032 1325145 R TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: ssn:SSON_2550 AcrD; aminoglycoside/multidrug efflux system complement(1322032..1325145) Escherichia coli ATCC 8739 6068734 YP_001724201.1 CDS EcolC_1208 NC_010468.1 1325309 1327009 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sdy:SDY_2653 sensor for nitrate reductase system; nitrate/nitrite sensor protein NarQ complement(1325309..1327009) Escherichia coli ATCC 8739 6066063 YP_001724202.1 CDS EcolC_1209 NC_010468.1 1327215 1329194 D unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 1327215..1329194 Escherichia coli ATCC 8739 6067092 YP_001724203.1 CDS EcolC_1210 NC_010468.1 1329262 1329837 D PFAM: NUDIX hydrolase; KEGG: sbo:SBO_2483 hypothetical protein; NUDIX hydrolase 1329262..1329837 Escherichia coli ATCC 8739 6064352 YP_001724204.1 CDS EcolC_1211 NC_010468.1 1329963 1331006 D PFAM: protein of unknown function DUF1176; KEGG: sbo:SBO_2482 hypothetical protein; hypothetical protein 1329963..1331006 Escherichia coli ATCC 8739 6067556 YP_001724205.1 CDS EcolC_1212 NC_010468.1 1331101 1333104 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1331101..1333104) Escherichia coli ATCC 8739 6065611 YP_001724206.1 CDS EcolC_1213 NC_010468.1 1333124 1334074 R KEGG: ssn:SSON_2544 transaldolase A; TIGRFAM: transaldolase; PFAM: Transaldolase; transaldolase A complement(1333124..1334074) Escherichia coli ATCC 8739 6067205 YP_001724207.1 CDS EcolC_1214 NC_010468.1 1334363 1336642 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 1334363..1336642 Escherichia coli ATCC 8739 6067672 YP_001724208.1 CDS EcolC_1215 NC_010468.1 1336935 1337270 D PFAM: microcompartments protein; KEGG: sfv:SFV_2506 hypothetical protein; microcompartments protein 1336935..1337270 Escherichia coli ATCC 8739 6064636 YP_001724209.1 CDS EcolC_1216 NC_010468.1 1337283 1337762 D TIGRFAM: ethanolamine utilization protein, EutP; KEGG: sbo:SBO_2476 hypothetical protein; ethanolamine utilization protein EutP 1337283..1337762 Escherichia coli ATCC 8739 6066266 YP_001724210.1 CDS EcolC_1217 NC_010468.1 1337737 1338438 D PFAM: protein of unknown function DUF861 cupin_3; Ethanolamine utilisation EutQ family protein; KEGG: ssn:SSON_2540 hypothetical protein; ethanolamine utilisation EutQ family protein 1337737..1338438 Escherichia coli ATCC 8739 6066237 YP_001724211.1 CDS EcolC_1218 NC_010468.1 1338435 1339244 D PFAM: cobalamin adenosyltransferase; KEGG: sbo:SBO_2474 hypothetical protein; cob(I)yrinic acid a,c-diamide adenosyltransferase 1338435..1339244 Escherichia coli ATCC 8739 6065205 YP_001724212.1 CDS eutD NC_010468.1 1339234 1340250 D in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1339234..1340250 Escherichia coli ATCC 8739 6066023 YP_001724213.1 CDS EcolC_1220 NC_010468.1 1340247 1340582 D PFAM: microcompartments protein; KEGG: sbo:SBO_2472 detox protein; microcompartments protein 1340247..1340582 Escherichia coli ATCC 8739 6067441 YP_001724214.1 CDS EcolC_1221 NC_010468.1 1340689 1340976 D PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: sbo:SBO_2471 detox protein; ethanolamine utilization protein EutN/carboxysome structural protein Ccml 1340689..1340976 Escherichia coli ATCC 8739 6067574 YP_001724215.1 CDS EcolC_1222 NC_010468.1 1340988 1342391 D PFAM: Aldehyde Dehydrogenase_; KEGG: sbo:SBO_2470 ethanolamine utilization; aldehyde dehydrogenase 1340988..1342391 Escherichia coli ATCC 8739 6065287 YP_001724216.1 CDS EcolC_1223 NC_010468.1 1342402 1343238 D TIGRFAM: ethanolamine utilization protein EutJ family protein; KEGG: sbo:SBO_2469 ethanolamine utilization; ethanolamine utilization protein EutJ family protein 1342402..1343238 Escherichia coli ATCC 8739 6065821 YP_001724217.1 CDS EcolC_1224 NC_010468.1 1343228 1344415 D PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2533 EutG; iron-containing alcohol dehydrogenase 1343228..1344415 Escherichia coli ATCC 8739 6067373 YP_001724218.1 CDS EcolC_1225 NC_010468.1 1344632 1345858 D PFAM: Ethanolamine utilisation protein EutH; KEGG: ssn:SSON_2532 EutH; ethanolamine utilisation protein EutH 1344632..1345858 Escherichia coli ATCC 8739 6067264 YP_001724219.1 CDS eutA NC_010468.1 1345855 1347258 D ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 1345855..1347258 Escherichia coli ATCC 8739 6066870 YP_001724220.1 CDS EcolC_1227 NC_010468.1 1347387 1347989 R KEGG: shw:Sputw3181_2459 DNA-binding protein; hypothetical protein complement(1347387..1347989) Escherichia coli ATCC 8739 6066905 YP_001724221.1 CDS EcolC_1228 NC_010468.1 1348203 1348985 R hypothetical protein complement(1348203..1348985) Escherichia coli ATCC 8739 6066573 YP_001724222.1 CDS EcolC_1229 NC_010468.1 1349125 1349601 R hypothetical protein complement(1349125..1349601) Escherichia coli ATCC 8739 6064589 YP_001724223.1 CDS EcolC_1230 NC_010468.1 1350122 1352302 R KEGG: esa:ESA_02313 hypothetical protein; hypothetical protein complement(1350122..1352302) Escherichia coli ATCC 8739 6065243 YP_001724224.1 CDS EcolC_1231 NC_010468.1 1352591 1352821 R KEGG: sfv:SFV_2497 hypothetical protein; hypothetical protein complement(1352591..1352821) Escherichia coli ATCC 8739 6065613 YP_001724225.1 CDS EcolC_1232 NC_010468.1 1352860 1353189 R KEGG: sfx:S2646 hypothetical protein; hypothetical protein complement(1352860..1353189) Escherichia coli ATCC 8739 6067625 YP_001724226.1 CDS EcolC_1233 NC_010468.1 1353286 1353828 R KEGG: sfv:SFV_2496 hypothetical protein; hypothetical protein complement(1353286..1353828) Escherichia coli ATCC 8739 6067605 YP_001724227.1 CDS EcolC_1234 NC_010468.1 1353846 1354109 R KEGG: sfv:SFV_2495 hypothetical protein; hypothetical protein complement(1353846..1354109) Escherichia coli ATCC 8739 6067495 YP_001724228.1 CDS EcolC_1235 NC_010468.1 1354127 1354522 R PFAM: HNH endonuclease; KEGG: sfx:S2643 hypothetical protein; HNH endonuclease complement(1354127..1354522) Escherichia coli ATCC 8739 6067474 YP_001724229.1 CDS EcolC_1236 NC_010468.1 1355181 1355510 D hypothetical protein 1355181..1355510 Escherichia coli ATCC 8739 6067420 YP_001724230.1 CDS EcolC_1237 NC_010468.1 1356303 1357508 R PFAM: integrase family protein; KEGG: ypp:YPDSF_3775 phage integrase; integrase family protein complement(1356303..1357508) Escherichia coli ATCC 8739 6067412 YP_001724231.1 CDS EcolC_1238 NC_010468.1 1357697 1359058 D PFAM: Ethanolamine ammonia lyase large subunit; KEGG: stm:STM2458 ethanolamine ammonia-lyase, heavy chain; ethanolamine ammonia lyase large subunit 1357697..1359058 Escherichia coli ATCC 8739 6067354 YP_001724232.1 CDS EcolC_1239 NC_010468.1 1359079 1359966 D catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 1359079..1359966 Escherichia coli ATCC 8739 6067290 YP_001724233.1 CDS EcolC_1240 NC_010468.1 1359976 1360635 D PFAM: microcompartments protein; KEGG: sbo:SBO_2464 hypothetical protein; microcompartments protein 1359976..1360635 Escherichia coli ATCC 8739 6067147 YP_001724234.1 CDS EcolC_1241 NC_010468.1 1360648 1361148 D PFAM: microcompartments protein; KEGG: sdy:SDY_2636 hypothetical protein; microcompartments protein 1360648..1361148 Escherichia coli ATCC 8739 6064841 YP_001724235.1 CDS EcolC_1242 NC_010468.1 1361194 1362246 D activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 1361194..1362246 Escherichia coli ATCC 8739 6066986 YP_001724236.1 CDS EcolC_1243 NC_010468.1 1362252 1363151 R catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase complement(1362252..1363151) Escherichia coli ATCC 8739 6066827 YP_001724237.1 CDS EcolC_1244 NC_010468.1 1363155 1364024 R PFAM: cell wall hydrolase/autolysin; KEGG: sbo:SBO_2460 N-acetylmuramoyl-L-alanine amidase I; N-acetylmuramoyl-l-alanine amidase I complement(1363155..1364024) Escherichia coli ATCC 8739 6066639 YP_001724238.1 CDS EcolC_1245 NC_010468.1 1364238 1364663 D PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_2632 hypothetical protein; putative acetyltransferase 1364238..1364663 Escherichia coli ATCC 8739 6066338 YP_001724239.1 CDS EcolC_1246 NC_010468.1 1364650 1365099 D KEGG: ssn:SSON_2522 hypothetical protein; hypothetical protein 1364650..1365099 Escherichia coli ATCC 8739 6066212 YP_001724240.1 CDS EcolC_1247 NC_010468.1 1365306 1365881 D PFAM: protein of unknown function DUF1131; KEGG: ssn:SSON_2521 hypothetical protein; hypothetical protein 1365306..1365881 Escherichia coli ATCC 8739 6066361 YP_001724241.1 CDS EcolC_1248 NC_010468.1 1365977 1366876 D TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbo:SBO_2456 hypothetical protein; Dyp-type peroxidase family protein 1365977..1366876 Escherichia coli ATCC 8739 6066123 YP_001724242.1 CDS EcolC_1249 NC_010468.1 1366934 1368238 R PFAM: beta-lactamase; KEGG: ssn:SSON_2519 putative beta-lactamase; hypothetical protein complement(1366934..1368238) Escherichia coli ATCC 8739 6066079 YP_001724243.1 CDS murP NC_010468.1 1368243 1369667 R belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC complement(1368243..1369667) Escherichia coli ATCC 8739 6065864 YP_001724244.1 CDS murQ NC_010468.1 1369671 1370567 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase complement(1369671..1370567) Escherichia coli ATCC 8739 6065765 YP_001724245.1 CDS EcolC_1252 NC_010468.1 1370731 1371588 D PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ssn:SSON_2516 hypothetical protein; RpiR family transcriptional regulator 1370731..1371588 Escherichia coli ATCC 8739 6065586 YP_001724246.1 CDS EcolC_1253 NC_010468.1 1371717 1372508 D PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbo:SBO_2451 putative oxidoreductase; short chain dehydrogenase 1371717..1372508 Escherichia coli ATCC 8739 6065528 YP_001724247.1 CDS EcolC_1254 NC_010468.1 1372666 1373682 D TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_2450 thiosulfate binding protein; thiosulfate transporter subunit 1372666..1373682 Escherichia coli ATCC 8739 6065578 YP_001724248.1 CDS EcolC_1255 NC_010468.1 1373682 1374515 D TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_2449 sulfate, thiosulfate transport system permease T protein; sulfate/thiosulfate transporter subunit 1373682..1374515 Escherichia coli ATCC 8739 6065476 YP_001724249.1 CDS cysW NC_010468.1 1374515 1375390 D Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease 1374515..1375390 Escherichia coli ATCC 8739 6065433 YP_001724250.1 CDS EcolC_1257 NC_010468.1 1375380 1376477 D KEGG: sbo:SBO_2447 ATP-binding component of sulfate permease A protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; sulfate/thiosulfate transporter subunit 1375380..1376477 Escherichia coli ATCC 8739 6065215 YP_001724251.1 CDS cysM NC_010468.1 1376611 1377522 D catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 1376611..1377522 Escherichia coli ATCC 8739 6065240 YP_001724252.1 CDS EcolC_1259 NC_010468.1 1377525 1377893 R KEGG: sbo:SBO_2445 hypothetical protein; hypothetical protein complement(1377525..1377893) Escherichia coli ATCC 8739 6065109 YP_001724253.1 CDS pdxK NC_010468.1 1377998 1378849 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 1377998..1378849 Escherichia coli ATCC 8739 6065064 YP_001724254.1 CDS EcolC_1261 NC_010468.1 1378892 1379401 R functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter complement(1378892..1379401) Escherichia coli ATCC 8739 6064952 YP_001724255.1 CDS EcolC_1262 NC_010468.1 1379442 1381169 R Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase complement(1379442..1381169) Escherichia coli ATCC 8739 6064788 YP_001724256.1 CDS EcolC_1263 NC_010468.1 1381214 1381471 R TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: stm:STM2431 PTS family, Hpr protein, phosphohistidinoprotein-hexose phosphotransferase; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr complement(1381214..1381471) Escherichia coli ATCC 8739 6064813 YP_001724257.1 CDS EcolC_1264 NC_010468.1 1381855 1382826 R CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A complement(1381855..1382826) Escherichia coli ATCC 8739 6064830 YP_001724258.1 CDS EcolC_1265 NC_010468.1 1383011 1383772 R putative role in sulfur assimilation; putative sulfate transport protein CysZ complement(1383011..1383772) Escherichia coli ATCC 8739 6064744 YP_001724259.1 CDS EcolC_1266 NC_010468.1 1384002 1384988 D interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 1384002..1384988 Escherichia coli ATCC 8739 6064705 YP_001724260.1 CDS ligA NC_010468.1 1385059 1387074 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1385059..1387074 Escherichia coli ATCC 8739 6064591 YP_001724261.1 CDS EcolC_1268 NC_010468.1 1387076 1387294 D KEGG: sdy:SDY_2607 Z3676 gene product; hypothetical protein 1387076..1387294 Escherichia coli ATCC 8739 6064643 YP_001724262.1 CDS EcolC_1269 NC_010468.1 1387291 1388289 R PFAM: Bile acid:sodium symporter; KEGG: ssn:SSON_2498 putative cytochrome oxidase; bile acid:sodium symporter complement(1387291..1388289) Escherichia coli ATCC 8739 6067064 YP_001724263.1 CDS EcolC_1270 NC_010468.1 1388379 1389305 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2432 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 1388379..1389305 Escherichia coli ATCC 8739 6067252 YP_001724264.1 CDS EcolC_1271 NC_010468.1 1389296 1389637 R KEGG: sfv:SFV_2459 hypothetical protein; hypothetical protein complement(1389296..1389637) Escherichia coli ATCC 8739 6066558 YP_001724265.1 CDS gltX NC_010468.1 1390413 1391828 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1390413..1391828 Escherichia coli ATCC 8739 6064541 YP_001724266.1 CDS EcolC_1273 NC_010468.1 1391880 1392272 R PFAM: protein of unknown function DUF1323; KEGG: sbo:SBO_2425 hypothetical protein; hypothetical protein complement(1391880..1392272) Escherichia coli ATCC 8739 6064486 YP_001724267.1 CDS EcolC_1274 NC_010468.1 1392274 1392633 R PFAM: protein of unknown function DUF1323; KEGG: sdy:SDY_2596 hypothetical protein; hypothetical protein complement(1392274..1392633) Escherichia coli ATCC 8739 6064478 YP_001724268.1 CDS EcolC_1275 NC_010468.1 1393253 1395442 D PFAM: GGDEF domain containing protein; EAL domain protein; MASE1 domain protein; KEGG: sbo:SBO_2421 hypothetical protein; diguanylate cyclase/phosphodiesterase 1393253..1395442 Escherichia coli ATCC 8739 6068173 YP_001724269.1 CDS EcolC_1276 NC_010468.1 1395526 1396638 D PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein 1395526..1396638 Escherichia coli ATCC 8739 6068717 YP_001724270.1 CDS EcolC_1277 NC_010468.1 1396841 1398043 R TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sdy:SDY_2593 permease of transport system for 3 nucleosides; nucleoside transporter complement(1396841..1398043) Escherichia coli ATCC 8739 6068405 YP_001724271.1 CDS EcolC_1278 NC_010468.1 1398379 1399617 D TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: sbo:SBO_2417 putative transport system permease; manganese transport protein MntH 1398379..1399617 Escherichia coli ATCC 8739 6065937 YP_001724272.1 CDS EcolC_1279 NC_010468.1 1399758 1400084 R KEGG: sbo:SBO_2416 hypothetical protein; hypothetical protein complement(1399758..1400084) Escherichia coli ATCC 8739 6068739 YP_001724273.1 CDS EcolC_1280 NC_010468.1 1400199 1401455 R PFAM: Chloride channel core; KEGG: sfv:SFV_2447 hypothetical protein; hypothetical protein complement(1400199..1401455) Escherichia coli ATCC 8739 6068727 YP_001724274.1 CDS glk NC_010468.1 1401659 1402624 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1401659..1402624 Escherichia coli ATCC 8739 6068725 YP_001724275.1 CDS EcolC_1282 NC_010468.1 1402843 1403169 D TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; KEGG: sbo:SBO_2413 putative PTS system enzyme IIB component; PTS system fructose-specific transporter subunit IIB 1402843..1403169 Escherichia coli ATCC 8739 6068713 YP_001724276.1 CDS EcolC_1283 NC_010468.1 1403191 1404438 D TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: ssn:SSON_2478 putative transport protein; PTS system fructose subfamily transporter subunit IIC 1403191..1404438 Escherichia coli ATCC 8739 6068709 YP_001724277.1 CDS EcolC_1284 NC_010468.1 1404453 1405538 D Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 1404453..1405538 Escherichia coli ATCC 8739 6068699 YP_001724278.1 CDS EcolC_1285 NC_010468.1 1405538 1406575 D metalloprotein; exoaminopeptidase 1405538..1406575 Escherichia coli ATCC 8739 6068696 YP_001724279.1 CDS EcolC_1286 NC_010468.1 1406600 1409095 D TIGRFAM: PTS system, fructose subfamily, IIA subunit; phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: sfv:SFV_2441 putative PTS system enzyme IIA component, enzyme I; phosphoenolpyruvate-protein phosphotransferase 1406600..1409095 Escherichia coli ATCC 8739 6068688 YP_001724280.1 CDS EcolC_1287 NC_010468.1 1409098 1409955 R PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_2474 putative AraC-type regulatory protein; AraC family transcriptional regulator complement(1409098..1409955) Escherichia coli ATCC 8739 6068685 YP_001724281.1 CDS EcolC_1288 NC_010468.1 1409968 1410702 R PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: sbo:SBO_2407 putative 2-component transcriptional regulator; LytTR family two component transcriptional regulator complement(1409968..1410702) Escherichia coli ATCC 8739 6068680 YP_001724282.1 CDS EcolC_1289 NC_010468.1 1410717 1412396 R PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: sbo:SBO_2406 putative sensor protein; signal transduction histidine kinase LytS complement(1410717..1412396) Escherichia coli ATCC 8739 6068671 YP_001724283.1 CDS EcolC_1290 NC_010468.1 1412791 1414029 D PFAM: aminotransferase class I and II; KEGG: ssn:SSON_2470 putative aminotransferase; aminotransferase 1412791..1414029 Escherichia coli ATCC 8739 6068665 YP_001724284.1 CDS EcolC_1291 NC_010468.1 1414521 1415441 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase complement(1414521..1415441) Escherichia coli ATCC 8739 6068662 YP_001724285.1 CDS EcolC_1292 NC_010468.1 1415794 1416036 D KEGG: sdy:SDY_2575 hypothetical protein; hypothetical protein 1415794..1416036 Escherichia coli ATCC 8739 6068656 YP_001724286.1 CDS EcolC_1293 NC_010468.1 1416113 1416388 R KEGG: ssn:SSON_2467 hypothetical protein; hypothetical protein complement(1416113..1416388) Escherichia coli ATCC 8739 6068644 YP_001724287.1 CDS EcolC_1294 NC_010468.1 1416684 1417316 D KEGG: sdy:SDY_2573 hypothetical protein; hypothetical protein 1416684..1417316 Escherichia coli ATCC 8739 6068638 YP_001724288.1 CDS EcolC_1295 NC_010468.1 1417829 1419079 D catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 1417829..1419079 Escherichia coli ATCC 8739 6068617 YP_001724289.1 CDS EcolC_1296 NC_010468.1 1419133 1420827 D catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase 1419133..1420827 Escherichia coli ATCC 8739 6068609 YP_001724290.1 CDS EcolC_1297 NC_010468.1 1420897 1421841 D member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV 1420897..1421841 Escherichia coli ATCC 8739 6068595 YP_001724291.1 CDS EcolC_1298 NC_010468.1 1421915 1423060 D PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sbo:SBO_2397 putative enzyme; hypothetical protein 1421915..1423060 Escherichia coli ATCC 8739 6068585 YP_001724292.1 CDS EcolC_1299 NC_010468.1 1423116 1426709 R PFAM: extracellular solute-binding protein family 3; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: sfv:SFV_2429 putative sensor for regulator EvgA; hybrid sensory histidine kinase in two-component regulatory system with EvgA complement(1423116..1426709) Escherichia coli ATCC 8739 6068577 YP_001724293.1 CDS EcolC_1300 NC_010468.1 1426714 1427328 R response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA complement(1426714..1427328) Escherichia coli ATCC 8739 6068574 YP_001724294.1 CDS EcolC_1301 NC_010468.1 1427744 1428907 D TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbo:SBO_2394 multidrug resistance protein K; efflux pump membrane protein 1427744..1428907 Escherichia coli ATCC 8739 6068571 YP_001724295.1 CDS EcolC_1302 NC_010468.1 1428907 1430445 D TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2393 multidrug resistance protein Y; EmrB/QacA family drug resistance transporter 1428907..1430445 Escherichia coli ATCC 8739 6068565 YP_001724296.1 CDS EcolC_1303 NC_010468.1 1430553 1431881 R catalyzes the formation of pyruvate from serine; D-serine dehydratase complement(1430553..1431881) Escherichia coli ATCC 8739 6068555 YP_001724297.1 CDS EcolC_1304 NC_010468.1 1431899 1433236 R member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX complement(1431899..1433236) Escherichia coli ATCC 8739 6068551 YP_001724298.1 CDS EcolC_1305 NC_010468.1 1433454 1434389 D regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 1433454..1434389 Escherichia coli ATCC 8739 6068547 YP_001724299.1 CDS EcolC_1306 NC_010468.1 1434635 1435567 R KEGG: sdy:SDY_2551 putative transport; putative transport complement(1434635..1435567) Escherichia coli ATCC 8739 6068535 YP_001724300.1 CDS EcolC_1307 NC_010468.1 1435861 1436616 D PFAM: VacJ family lipoprotein; KEGG: sdy:SDY_2550 lipoprotein precursor; VacJ family lipoprotein 1435861..1436616 Escherichia coli ATCC 8739 6068530 YP_001724301.1 CDS EcolC_1308 NC_010468.1 1436798 1437856 R KEGG: sfx:S2558 hypothetical protein; hypothetical protein complement(1436798..1437856) Escherichia coli ATCC 8739 6068528 YP_001724302.1 CDS EcolC_1309 NC_010468.1 1438223 1439563 R PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: ssn:SSON_2400 transport of long-chain fatty acids; sensitivity to phage T2; long-chain fatty acid outer membrane transporter complement(1438223..1439563) Escherichia coli ATCC 8739 6068526 YP_001724303.1 CDS EcolC_1310 NC_010468.1 1439935 1440219 D PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2381 hypothetical protein; hypothetical protein 1439935..1440219 Escherichia coli ATCC 8739 6068505 YP_001724304.1 CDS fadI NC_010468.1 1440400 1441710 D FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 1440400..1441710 Escherichia coli ATCC 8739 6068500 YP_001724305.1 CDS fadJ NC_010468.1 1441710 1443854 D multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 1441710..1443854 Escherichia coli ATCC 8739 6068474 YP_001724306.1 CDS EcolC_1313 NC_010468.1 1444057 1444542 D TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: sbo:SBO_2378 hypothetical protein; phosphohistidine phosphatase 1444057..1444542 Escherichia coli ATCC 8739 6068465 YP_001724307.1 CDS EcolC_1314 NC_010468.1 1445226 1445789 D PFAM: Fimbrial protein; KEGG: sfx:S2550 putative fimbrial-like protein; fimbrial protein 1445226..1445789 Escherichia coli ATCC 8739 6068458 YP_001724308.1 CDS EcolC_1315 NC_010468.1 1445872 1448517 D PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sbo:SBO_2376 PapC-like porin protein; fimbrial biogenesis outer membrane usher protein 1445872..1448517 Escherichia coli ATCC 8739 6068451 YP_001724309.1 CDS EcolC_1316 NC_010468.1 1448537 1449289 D PFAM: pili assembly chaperone; KEGG: sbo:SBO_2375 putative chaperone; pili assembly chaperone 1448537..1449289 Escherichia coli ATCC 8739 6068441 YP_001724310.1 CDS EcolC_1317 NC_010468.1 1449305 1449814 D KEGG: sbo:SBO_2374 putative fimbrial protein; putative fimbrial protein 1449305..1449814 Escherichia coli ATCC 8739 6068436 YP_001724311.1 CDS EcolC_1318 NC_010468.1 1449811 1450299 D KEGG: sbo:SBO_2373 hypothetical protein; hypothetical protein 1449811..1450299 Escherichia coli ATCC 8739 6068423 YP_001724312.1 CDS EcolC_1319 NC_010468.1 1450296 1450835 D PFAM: Fimbrial protein; KEGG: sbo:SBO_2372 putative fimbrial-like protein; fimbrial protein 1450296..1450835 Escherichia coli ATCC 8739 6068419 YP_001724313.1 CDS EcolC_1320 NC_010468.1 1450837 1451694 D KEGG: sbo:SBO_2369 hypothetical protein; hypothetical protein 1450837..1451694 Escherichia coli ATCC 8739 6068412 YP_001724314.1 CDS EcolC_1321 NC_010468.1 1451766 1452317 R PFAM: Smr protein/MutS2; KEGG: sbo:SBO_2367 hypothetical protein; hypothetical protein complement(1451766..1452317) Escherichia coli ATCC 8739 6068393 YP_001724315.1 CDS EcolC_1322 NC_010468.1 1452483 1453415 D involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1452483..1453415 Escherichia coli ATCC 8739 6068389 YP_001724316.1 CDS EcolC_1323 NC_010468.1 1453450 1454535 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1453450..1454535 Escherichia coli ATCC 8739 6068370 YP_001724317.1 CDS mepA NC_010468.1 1454539 1455363 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1454539..1455363 Escherichia coli ATCC 8739 6068353 YP_001724318.1 CDS EcolC_1325 NC_010468.1 1455363 1456172 D PFAM: protein of unknown function DUF81; KEGG: ssn:SSON_2385 putative structural protein; hypothetical protein 1455363..1456172 Escherichia coli ATCC 8739 6068335 YP_001724319.1 CDS EcolC_1326 NC_010468.1 1456172 1456720 D PFAM: protein of unknown function DUF462; KEGG: sfx:S2537 putative transporting ATPase; hypothetical protein 1456172..1456720 Escherichia coli ATCC 8739 6068330 YP_001724320.1 CDS EcolC_1327 NC_010468.1 1456754 1457032 D PFAM: YfcL protein; KEGG: sdy:SDY_2524 hypothetical protein; hypothetical protein 1456754..1457032 Escherichia coli ATCC 8739 6068324 YP_001724321.1 CDS mnmC NC_010468.1 1457153 1459159 R catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase complement(1457153..1459159) Escherichia coli ATCC 8739 6068320 YP_001724322.1 CDS EcolC_1329 NC_010468.1 1459318 1460538 D FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1459318..1460538 Escherichia coli ATCC 8739 6068309 YP_001724323.1 CDS EcolC_1330 NC_010468.1 1460803 1461981 D PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2380 putative transport protein; hypothetical protein 1460803..1461981 Escherichia coli ATCC 8739 6068296 YP_001724324.1 CDS flk NC_010468.1 1461978 1462973 R in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator complement(1461978..1462973) Escherichia coli ATCC 8739 6068284 YP_001724325.1 CDS EcolC_1332 NC_010468.1 1463072 1464208 D PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_2378 erythronate-4-phosphate dehyrogenase; D-isomer specific 2-hydroxyacid dehydrogenase catalytic subunit 1463072..1464208 Escherichia coli ATCC 8739 6068275 YP_001724326.1 CDS EcolC_1333 NC_010468.1 1464274 1465287 D PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: sdy:SDY_2518 putative PTS system enzyme II A component; putative semialdehyde dehydrogenase 1464274..1465287 Escherichia coli ATCC 8739 6068267 YP_001724327.1 CDS truA NC_010468.1 1465287 1466099 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1465287..1466099 Escherichia coli ATCC 8739 6068265 YP_001724328.1 CDS EcolC_1335 NC_010468.1 1466182 1466841 D PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_2386 hypothetical protein; hypothetical protein 1466182..1466841 Escherichia coli ATCC 8739 6068247 YP_001724329.1 CDS EcolC_1336 NC_010468.1 1466997 1467911 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1466997..1467911 Escherichia coli ATCC 8739 6068239 YP_001724330.1 CDS EcolC_1337 NC_010468.1 1467981 1469249 D TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_2352 dihydrofolate:folylpolyglutamate synthetase; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 1467981..1469249 Escherichia coli ATCC 8739 6068235 YP_001724331.1 CDS EcolC_1338 NC_010468.1 1469239 1469901 D PFAM: Sporulation domain protein; KEGG: sbo:SBO_2351 putative lipoprotein; hypothetical protein 1469239..1469901 Escherichia coli ATCC 8739 6068224 YP_001724332.1 CDS EcolC_1339 NC_010468.1 1470160 1470648 D membrane protein required for colicin V production; colicin V production protein 1470160..1470648 Escherichia coli ATCC 8739 6068222 YP_001724333.1 CDS EcolC_1340 NC_010468.1 1470685 1472202 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1470685..1472202 Escherichia coli ATCC 8739 6068218 YP_001724334.1 CDS EcolC_1341 NC_010468.1 1472297 1472866 D catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1472297..1472866 Escherichia coli ATCC 8739 6068214 YP_001724335.1 CDS EcolC_1342 NC_010468.1 1473132 1473914 D TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: ssn:SSON_2368 lysine-, arginine-, ornithine-binding periplasmic protein; cationic amino acid ABC transporter periplasmic binding protein 1473132..1473914 Escherichia coli ATCC 8739 6068211 YP_001724336.1 CDS EcolC_1343 NC_010468.1 1474135 1474917 D TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: sbo:SBO_2346 histidine-binding periplasmic protein of high-affinity histidine transport system; cationic amino acid ABC transporter periplasmic binding protein 1474135..1474917 Escherichia coli ATCC 8739 6068205 YP_001724337.1 CDS EcolC_1344 NC_010468.1 1475007 1475693 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_2507 histidine transport system permease protein; polar amino acid ABC transporter inner membrane protein 1475007..1475693 Escherichia coli ATCC 8739 6068202 YP_001724338.1 CDS EcolC_1345 NC_010468.1 1475690 1476406 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_2506 histidine transport, membrane protein M; polar amino acid ABC transporter inner membrane protein 1475690..1476406 Escherichia coli ATCC 8739 6068200 YP_001724339.1 CDS EcolC_1346 NC_010468.1 1476414 1477187 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_2364 ATP-binding component of histidine transport; histidine/lysine/arginine/ornithine transporter subunit 1476414..1477187 Escherichia coli ATCC 8739 6068196 YP_001724340.1 CDS EcolC_1347 NC_010468.1 1477384 1478274 D PFAM: putative transposase YhgA family protein; KEGG: sfv:SFV_2372 hypothetical protein; putative transposase YhgA family protein 1477384..1478274 Escherichia coli ATCC 8739 6068192 YP_001724341.1 CDS EcolC_1348 NC_010468.1 1478322 1479215 R PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; domain of unknown function DUF1731; KEGG: sbo:SBO_2339 putative sugar nucleotide epimerase; hypothetical protein complement(1478322..1479215) Escherichia coli ATCC 8739 6068190 YP_001724342.1 CDS folX NC_010468.1 1479236 1479598 R catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase complement(1479236..1479598) Escherichia coli ATCC 8739 6068186 YP_001724343.1 CDS EcolC_1350 NC_010468.1 1479655 1480302 R PFAM: Glutathione S-transferase domain; KEGG: ssn:SSON_2359 putative S-transferase; glutathione S-transferase complement(1479655..1480302) Escherichia coli ATCC 8739 6068184 YP_001724344.1 CDS EcolC_1351 NC_010468.1 1480438 1481082 D PFAM: Glutathione S-transferase domain; KEGG: sfv:SFV_2368 hypothetical protein; glutathione S-transferase domain-containing protein 1480438..1481082 Escherichia coli ATCC 8739 6068180 YP_001724345.1 CDS EcolC_1352 NC_010468.1 1481138 1481689 D TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: sbo:SBO_2335 hypothetical protein; phosphodiesterase 1481138..1481689 Escherichia coli ATCC 8739 6068178 YP_001724346.1 CDS EcolC_1353 NC_010468.1 1481747 1482289 D PFAM: NUDIX hydrolase; KEGG: sbo:SBO_2334 putative regulator; NUDIX hydrolase 1481747..1482289 Escherichia coli ATCC 8739 6068176 YP_001724347.1 CDS EcolC_1354 NC_010468.1 1482322 1483800 R PFAM: C4-dicarboxylate anaerobic carrier; KEGG: ssn:SSON_2355 putative S-transferase; hypothetical protein complement(1482322..1483800) Escherichia coli ATCC 8739 6068172 YP_001724348.1 CDS EcolC_1355 NC_010468.1 1484032 1486176 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(1484032..1486176) Escherichia coli ATCC 8739 6068169 YP_001724349.1 CDS EcolC_1356 NC_010468.1 1486251 1487453 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1486251..1487453) Escherichia coli ATCC 8739 6068166 YP_001724350.1 CDS EcolC_1357 NC_010468.1 1487792 1488247 D PFAM: protein of unknown function DUF412; KEGG: sdy:SDY_2491 hypothetical protein; hypothetical protein 1487792..1488247 Escherichia coli ATCC 8739 6068164 YP_001724351.1 CDS EcolC_1358 NC_010468.1 1488330 1488824 D PFAM: YfbU family protein; KEGG: sdy:SDY_2490 hypothetical protein; hypothetical protein 1488330..1488824 Escherichia coli ATCC 8739 6068162 YP_001724352.1 CDS EcolC_1359 NC_010468.1 1488835 1489485 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfv:SFV_2360 putative phosphatase; putative phosphatase 1488835..1489485 Escherichia coli ATCC 8739 6068158 YP_001724353.1 CDS EcolC_1360 NC_010468.1 1489572 1491404 D PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ssn:SSON_2349 putative transport protein; citrate transporter 1489572..1491404 Escherichia coli ATCC 8739 6068156 YP_001724354.1 CDS EcolC_1361 NC_010468.1 1491463 1492062 R KEGG: sfv:SFV_2358 putative alpha helix protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; hypothetical protein complement(1491463..1492062) Escherichia coli ATCC 8739 6068152 YP_001724355.1 CDS EcolC_1362 NC_010468.1 1492146 1493363 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(1492146..1493363) Escherichia coli ATCC 8739 6068149 YP_001724356.1 CDS EcolC_1363 NC_010468.1 1494283 1495221 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2322 NADH dehydrogenase transcriptional regulator; LysR family transcriptional regulator 1494283..1495221 Escherichia coli ATCC 8739 6068147 YP_001724357.1 CDS EcolC_1364 NC_010468.1 1495852 1496295 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 1495852..1496295 Escherichia coli ATCC 8739 6068145 YP_001724358.1 CDS EcolC_1365 NC_010468.1 1496311 1496973 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1496311..1496973 Escherichia coli ATCC 8739 6068143 YP_001724359.1 CDS EcolC_1366 NC_010468.1 1497067 1498869 D NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 1497067..1498869 Escherichia coli ATCC 8739 6068139 YP_001724360.1 CDS EcolC_1367 NC_010468.1 1498872 1499372 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 1498872..1499372 Escherichia coli ATCC 8739 6068137 YP_001724361.1 CDS EcolC_1368 NC_010468.1 1499369 1500706 D shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 1499369..1500706 Escherichia coli ATCC 8739 6068134 YP_001724362.1 CDS EcolC_1369 NC_010468.1 1500759 1503485 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 1500759..1503485 Escherichia coli ATCC 8739 6068129 YP_001724363.1 CDS EcolC_1370 NC_010468.1 1503482 1504459 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 1503482..1504459 Escherichia coli ATCC 8739 6068123 YP_001724364.1 CDS EcolC_1371 NC_010468.1 1504474 1505016 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1504474..1505016 Escherichia coli ATCC 8739 6068120 YP_001724365.1 CDS EcolC_1372 NC_010468.1 1505028 1505582 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 1505028..1505582 Escherichia coli ATCC 8739 6068117 YP_001724366.1 CDS EcolC_1373 NC_010468.1 1505579 1505881 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 1505579..1505881 Escherichia coli ATCC 8739 6068107 YP_001724367.1 CDS EcolC_1374 NC_010468.1 1505878 1507719 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1505878..1507719 Escherichia coli ATCC 8739 6068098 YP_001724368.1 CDS EcolC_1375 NC_010468.1 1507883 1509412 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 1507883..1509412 Escherichia coli ATCC 8739 6068083 YP_001724369.1 CDS EcolC_1376 NC_010468.1 1509419 1510876 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 1509419..1510876 Escherichia coli ATCC 8739 6068078 YP_001724370.1 CDS EcolC_1377 NC_010468.1 1510943 1511446 R PFAM: Domain of unknown function DUF1877; KEGG: sdy:SDY_2471 hypothetical protein; hypothetical protein complement(1510943..1511446) Escherichia coli ATCC 8739 6068072 YP_001724371.1 CDS EcolC_1380 NC_010468.1 1513995 1514912 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(1513995..1514912) Escherichia coli ATCC 8739 6068055 YP_001724372.1 CDS EcolC_1381 NC_010468.1 1514977 1515438 D PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_2338 hypothetical protein; hypothetical protein 1514977..1515438 Escherichia coli ATCC 8739 6068047 YP_001724373.1 CDS EcolC_1382 NC_010468.1 1515493 1515798 D PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2462 hypothetical protein; hypothetical protein 1515493..1515798 Escherichia coli ATCC 8739 6068041 YP_001724374.1 CDS EcolC_1383 NC_010468.1 1515877 1517172 D TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: sfv:SFV_2336 isochorismate hydroxymutase 2; isochorismate synthase 1515877..1517172 Escherichia coli ATCC 8739 6068036 YP_001724375.1 CDS EcolC_1384 NC_010468.1 1517261 1518931 D SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1517261..1518931 Escherichia coli ATCC 8739 6068024 YP_001724376.1 CDS EcolC_1385 NC_010468.1 1518928 1519686 D catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 1518928..1519686 Escherichia coli ATCC 8739 6068015 YP_001724377.1 CDS EcolC_1386 NC_010468.1 1519701 1520558 D catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1519701..1520558 Escherichia coli ATCC 8739 6068005 YP_001724378.1 CDS EcolC_1387 NC_010468.1 1520558 1521520 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 1520558..1521520 Escherichia coli ATCC 8739 6067995 YP_001724379.1 CDS EcolC_1388 NC_010468.1 1521517 1522872 D TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: sdy:SDY_2456 O-succinylbenzoate-CoA ligase; O-succinylbenzoic acid--CoA ligase 1521517..1522872 Escherichia coli ATCC 8739 6067985 YP_001724380.1 CDS EcolC_1389 NC_010468.1 1522982 1523248 D KEGG: ssn:SSON_2320 polymyxin resistance protein B; polymyxin resistance protein B 1522982..1523248 Escherichia coli ATCC 8739 6067972 YP_001724381.1 CDS EcolC_1390 NC_010468.1 1523242 1523628 R KEGG: sbo:SBO_2295 putative transport/receptor protein; hypothetical protein complement(1523242..1523628) Escherichia coli ATCC 8739 6067957 YP_001724382.1 CDS EcolC_1391 NC_010468.1 1523628 1523963 R PFAM: small multidrug resistance protein; KEGG: sfx:S2567 sucrose-6 phosphate hydrolase; small multidrug resistance protein complement(1523628..1523963) Escherichia coli ATCC 8739 6067952 YP_001724383.1 CDS arnT NC_010468.1 1523960 1525612 R catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase complement(1523960..1525612) Escherichia coli ATCC 8739 6067949 YP_001724384.1 CDS EcolC_1393 NC_010468.1 1525612 1526502 R PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_2317 hypothetical protein; polysaccharide deacetylase complement(1525612..1526502) Escherichia coli ATCC 8739 6067940 YP_001724385.1 CDS EcolC_1394 NC_010468.1 1526499 1528481 R Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase complement(1526499..1528481) Escherichia coli ATCC 8739 6067936 YP_001724386.1 CDS EcolC_1395 NC_010468.1 1528481 1529449 R catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase complement(1528481..1529449) Escherichia coli ATCC 8739 6067920 YP_001724387.1 CDS EcolC_1396 NC_010468.1 1529453 1530592 R catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase complement(1529453..1530592) Escherichia coli ATCC 8739 6067914 YP_001724388.1 CDS EcolC_1397 NC_010468.1 1530900 1531502 D PFAM: Phosphoglycerate mutase; KEGG: ssn:SSON_2313 protein induced by aluminum; phosphoglycerate mutase 1530900..1531502 Escherichia coli ATCC 8739 6067908 YP_001724389.1 CDS EcolC_1398 NC_010468.1 1531541 1531966 R PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2321 hypothetical protein; NUDIX hydrolase complement(1531541..1531966) Escherichia coli ATCC 8739 6067905 YP_001724390.1 CDS EcolC_1399 NC_010468.1 1532245 1532787 D PFAM: YfaZ family protein; KEGG: ssn:SSON_2311 hypothetical protein; hypothetical protein 1532245..1532787 Escherichia coli ATCC 8739 6067897 YP_001724391.1 CDS EcolC_1400 NC_010468.1 1532887 1534089 D TIGRFAM: molybdenum cofactor synthesis domain protein; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: sfx:S2461 competence/damage-inducible protein CinA; competence damage-inducible protein A 1532887..1534089 Escherichia coli ATCC 8739 6067885 YP_001724392.1 CDS EcolC_1401 NC_010468.1 1534309 1535091 D PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ssn:SSON_2309 putative regulator; IclR family transcriptional regulator 1534309..1535091 Escherichia coli ATCC 8739 6067878 YP_001724393.1 CDS EcolC_1402 NC_010468.1 1535106 1536311 D PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sbo:SBO_2047 putative racemase; mandelate racemase/muconate lactonizing protein 1535106..1536311 Escherichia coli ATCC 8739 6067871 YP_001724394.1 CDS EcolC_1403 NC_010468.1 1536368 1537657 D PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2048 putative transport protein; major facilitator transporter 1536368..1537657 Escherichia coli ATCC 8739 6067866 YP_001724395.1 CDS EcolC_1404 NC_010468.1 1537675 1538478 D PFAM: HpcH/HpaI aldolase; KEGG: ssn:SSON_2306 hypothetical protein; putative aldolase 1537675..1538478 Escherichia coli ATCC 8739 6067853 YP_001724396.1 CDS EcolC_1406 NC_010468.1 1538717 1539616 R PFAM: putative transposase YhgA family protein; KEGG: sbo:SBO_2050 hypothetical protein; hypothetical protein complement(1538717..1539616) Escherichia coli ATCC 8739 6067849 YP_001724397.1 CDS EcolC_1407 NC_010468.1 1539659 1539784 R hypothetical protein complement(1539659..1539784) Escherichia coli ATCC 8739 6067844 YP_001724398.1 CDS glpC NC_010468.1 1539809 1540999 R anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C complement(1539809..1540999) Escherichia coli ATCC 8739 6067836 YP_001724399.1 CDS EcolC_1409 NC_010468.1 1540996 1542255 R sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(1540996..1542255) Escherichia coli ATCC 8739 6067831 YP_001724400.1 CDS glpA NC_010468.1 1542245 1543873 R anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A complement(1542245..1543873) Escherichia coli ATCC 8739 6067823 YP_001724401.1 CDS glpT NC_010468.1 1544146 1545504 D catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 1544146..1545504 Escherichia coli ATCC 8739 6067811 YP_001724402.1 CDS glpQ NC_010468.1 1545509 1546585 D hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 1545509..1546585 Escherichia coli ATCC 8739 6067805 YP_001724403.1 CDS EcolC_1413 NC_010468.1 1546627 1546833 R KEGG: sbo:SBO_2056 hypothetical protein; hypothetical protein complement(1546627..1546833) Escherichia coli ATCC 8739 6067797 YP_001724404.1 CDS EcolC_1414 NC_010468.1 1547048 1547698 D PFAM: lipopolysaccharide kinase; KEGG: sfv:SFV_2310 pH-inducible protein involved in stress response; hypothetical protein 1547048..1547698 Escherichia coli ATCC 8739 6067793 YP_001724405.1 CDS EcolC_1415 NC_010468.1 1547752 1548006 R plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin complement(1547752..1548006) Escherichia coli ATCC 8739 6067779 YP_001724406.1 CDS nrdB NC_010468.1 1548006 1549175 R B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta complement(1548006..1549175) Escherichia coli ATCC 8739 6067771 YP_001724407.1 CDS EcolC_1417 NC_010468.1 1549370 1551655 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1549370..1551655) Escherichia coli ATCC 8739 6067765 YP_001724408.1 CDS EcolC_1418 NC_010468.1 1552399 1556103 D TIGRFAM: polymorphic outer membrane protein; outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Polymorphic membrane protein Chlamydia; Pertactin; Autotransporter beta- domain protein; KEGG: sdy:SDY_2425 putative ATP-binding component of a transport system; adhesin 1552399..1556103 Escherichia coli ATCC 8739 6067759 YP_001724409.1 CDS EcolC_1419 NC_010468.1 1556231 1556953 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(1556231..1556953) Escherichia coli ATCC 8739 6067748 YP_001724410.1 CDS EcolC_1420 NC_010468.1 1557100 1559727 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1557100..1559727 Escherichia coli ATCC 8739 6067746 YP_001724411.1 CDS EcolC_1421 NC_010468.1 1559876 1561564 D KEGG: ssn:SSON_2288 hypothetical protein; hypothetical protein 1559876..1561564 Escherichia coli ATCC 8739 6067734 YP_001724412.1 CDS EcolC_1422 NC_010468.1 1561561 1562184 D PFAM: protein of unknown function DUF1175; KEGG: sfv:SFV_2299 hypothetical protein; hypothetical protein 1561561..1562184 Escherichia coli ATCC 8739 6067718 YP_001724413.1 CDS EcolC_1423 NC_010468.1 1562208 1566722 D PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: sdy:SDY_0852 large extracellular alpha-helical protein; alpha-2-macroglobulin domain-containing protein 1562208..1566722 Escherichia coli ATCC 8739 6067710 YP_001724414.1 CDS EcolC_1424 NC_010468.1 1566723 1568372 D KEGG: ssn:SSON_2285 hypothetical protein; hypothetical protein 1566723..1568372 Escherichia coli ATCC 8739 6067697 YP_001724415.1 CDS EcolC_1425 NC_010468.1 1568377 1569153 D KEGG: sfv:SFV_2294 hypothetical protein; hypothetical protein 1568377..1569153 Escherichia coli ATCC 8739 6067693 YP_001724416.1 CDS EcolC_1426 NC_010468.1 1569227 1570411 R KEGG: ssn:SSON_2283 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; acetyl-CoA acetyltransferase complement(1569227..1570411) Escherichia coli ATCC 8739 6067686 YP_001724417.1 CDS EcolC_1427 NC_010468.1 1570442 1571764 R PFAM: short chain fatty acid transporter; KEGG: ssn:SSON_2282 short chain fatty acid transporter; short chain fatty acid transporter complement(1570442..1571764) Escherichia coli ATCC 8739 6067684 YP_001724418.1 CDS EcolC_1428 NC_010468.1 1571761 1572411 R KEGG: ssn:SSON_2281 acetyl-CoA:acetoacetyl-CoA transferase beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase; 3-oxoacid CoA-transferase subunit B complement(1571761..1572411) Escherichia coli ATCC 8739 6067681 YP_001724419.1 CDS EcolC_1429 NC_010468.1 1572411 1573073 R KEGG: ssn:SSON_2280 acetyl-CoA:acetoacetyl-CoA transferase alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha complement(1572411..1573073) Escherichia coli ATCC 8739 6067670 YP_001724420.1 CDS EcolC_1430 NC_010468.1 1573269 1574654 R with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC complement(1573269..1574654) Escherichia coli ATCC 8739 6067656 YP_001724421.1 CDS EcolC_1431 NC_010468.1 1574651 1576477 R with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS complement(1574651..1576477) Escherichia coli ATCC 8739 6067643 YP_001724422.1 CDS EcolC_1432 NC_010468.1 1576644 1579493 D PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase; KEGG: sfx:S2433 sensor for ctr capsule biosynthesis, probable histidine kinase acting on RcsB; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 1576644..1579493 Escherichia coli ATCC 8739 6067640 YP_001724423.1 CDS EcolC_1433 NC_010468.1 1579693 1580343 R two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB complement(1579693..1580343) Escherichia coli ATCC 8739 6067621 YP_001724424.1 CDS EcolC_1434 NC_010468.1 1580360 1583032 R PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: sbo:SBO_2091 putative 2-component sensor protein; phosphotransfer intermediate protein in two-component regulatory system with RcsBC complement(1580360..1583032) Escherichia coli ATCC 8739 6067602 YP_001724425.1 CDS EcolC_1435 NC_010468.1 1583771 1584901 D allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 1583771..1584901 Escherichia coli ATCC 8739 6067592 YP_001724426.1 CDS EcolC_1436 NC_010468.1 1585013 1586068 D catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 1585013..1586068 Escherichia coli ATCC 8739 6067573 YP_001724427.1 CDS EcolC_1437 NC_010468.1 1586142 1587206 D KEGG: sbo:SBO_2094 O6-methylguanine-DNA methyltransferase; transcription activator/repressor; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; AraC family transcriptional regulator 1586142..1587206 Escherichia coli ATCC 8739 6067560 YP_001724428.1 CDS EcolC_1438 NC_010468.1 1587206 1587856 D TIGRFAM: alkylated DNA repair protein AlkB; PFAM: 2OG-Fe(II) oxygenase; KEGG: sbo:SBO_2095 AlkB; alkylated DNA repair protein AlkB 1587206..1587856 Escherichia coli ATCC 8739 6067548 YP_001724429.1 CDS EcolC_1439 NC_010468.1 1587932 1589575 D efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding protein 1587932..1589575 Escherichia coli ATCC 8739 6067542 YP_001724430.1 CDS EcolC_1440 NC_010468.1 1589793 1591439 D malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1589793..1591439 Escherichia coli ATCC 8739 6067525 YP_001724431.1 CDS EcolC_1441 NC_010468.1 1592156 1592644 R serine protease inhibitor, inhibits trypsin and other proteases; ecotin complement(1592156..1592644) Escherichia coli ATCC 8739 6067509 YP_001724432.1 CDS EcolC_1442 NC_010468.1 1593052 1593546 D Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 1593052..1593546 Escherichia coli ATCC 8739 6067491 YP_001724433.1 CDS EcolC_1443 NC_010468.1 1593536 1593799 D PFAM: NapD family protein; KEGG: sbo:SBO_2100 hypothetical protein; assembly protein for periplasmic nitrate reductase 1593536..1593799 Escherichia coli ATCC 8739 6067482 YP_001724434.1 CDS EcolC_1444 NC_010468.1 1593796 1596282 D periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 1593796..1596282 Escherichia coli ATCC 8739 6067475 YP_001724435.1 CDS napG NC_010468.1 1596289 1596984 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic protein 1596289..1596984 Escherichia coli ATCC 8739 6067453 YP_001724436.1 CDS napH NC_010468.1 1596971 1597834 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane protein 1596971..1597834 Escherichia coli ATCC 8739 6067439 YP_001724437.1 CDS napB NC_010468.1 1597831 1598280 D small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 1597831..1598280 Escherichia coli ATCC 8739 6067424 YP_001724438.1 CDS EcolC_1448 NC_010468.1 1598290 1598892 D with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 1598290..1598892 Escherichia coli ATCC 8739 6067401 YP_001724439.1 CDS EcolC_1449 NC_010468.1 1598911 1599528 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1598911..1599528 Escherichia coli ATCC 8739 6067395 YP_001724440.1 CDS EcolC_1450 NC_010468.1 1599525 1600187 D TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: sdy:SDY_0878 heme exporter protein B; heme exporter protein CcmB 1599525..1600187 Escherichia coli ATCC 8739 6067393 YP_001724441.1 CDS EcolC_1451 NC_010468.1 1600229 1600966 D TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: sdy:SDY_0879 heme exporter protein C; heme exporter protein CcmC 1600229..1600966 Escherichia coli ATCC 8739 6067389 YP_001724442.1 CDS EcolC_1452 NC_010468.1 1600963 1601172 D TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: sdy:SDY_0880 heme exporter protein C; heme exporter protein CcmD 1600963..1601172 Escherichia coli ATCC 8739 6067370 YP_001724443.1 CDS EcolC_1453 NC_010468.1 1601169 1601648 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 1601169..1601648 Escherichia coli ATCC 8739 6067365 YP_001724444.1 CDS EcolC_1454 NC_010468.1 1601645 1603588 D TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: sbo:SBO_2111 cytochrome c-type biogenesis protein; cytochrome c-type biogenesis protein CcmF 1601645..1603588 Escherichia coli ATCC 8739 6067355 YP_001724445.1 CDS EcolC_1455 NC_010468.1 1603585 1604142 D TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sbo:SBO_2112 disulfide oxidoreductase; periplasmic protein thiol--disulfide oxidoreductase DsbE 1603585..1604142 Escherichia coli ATCC 8739 6067342 YP_001724446.1 CDS EcolC_1456 NC_010468.1 1604139 1605191 D PFAM: cytochrome C biogenesis protein; KEGG: sfv:SFV_2270 possible subunit of heme lyase; cytochrome C biogenesis protein 1604139..1605191 Escherichia coli ATCC 8739 6067334 YP_001724447.1 CDS EcolC_1457 NC_010468.1 1605226 1605873 R nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP complement(1605226..1605873) Escherichia coli ATCC 8739 6067321 YP_001724448.1 CDS EcolC_1458 NC_010468.1 1606193 1608784 D TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfv:SFV_2268 putative ATP-binding component of a transport system; outer membrane autotransporter 1606193..1608784 Escherichia coli ATCC 8739 6067311 YP_001724449.1 CDS EcolC_1459 NC_010468.1 1609038 1610798 R PFAM: sulfatase; KEGG: ssn:SSON_2244 putative sulfatase; sulfatase complement(1609038..1610798) Escherichia coli ATCC 8739 6067304 YP_001724450.1 CDS EcolC_1460 NC_010468.1 1610818 1611045 R PFAM: protein of unknown function DUF1414; KEGG: sbo:SBO_2137 hypothetical protein; hypothetical protein complement(1610818..1611045) Escherichia coli ATCC 8739 6067288 YP_001724451.1 CDS EcolC_1461 NC_010468.1 1611227 1612234 D PFAM: 37kDa nucleoid-associated protein; KEGG: sdy:SDY_0893 hypothetical protein; nucleoid-associated protein NdpA 1611227..1612234 Escherichia coli ATCC 8739 6067286 YP_001724452.1 CDS EcolC_1462 NC_010468.1 1612373 1612657 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1612373..1612657) Escherichia coli ATCC 8739 6067280 YP_001724453.1 CDS EcolC_1463 NC_010468.1 1612782 1614542 R PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sdy:SDY_0895 putative ATP-dependent helicase; type III restriction protein res subunit complement(1612782..1614542) Escherichia coli ATCC 8739 6067277 YP_001724454.1 CDS EcolC_1464 NC_010468.1 1614691 1615386 D catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 1614691..1615386 Escherichia coli ATCC 8739 6067263 YP_001724455.1 CDS EcolC_1465 NC_010468.1 1615414 1616604 D Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 1615414..1616604 Escherichia coli ATCC 8739 6067255 YP_001724456.1 CDS EcolC_1466 NC_010468.1 1616937 1617281 D KEGG: sdy:SDY_0898 hypothetical protein; hypothetical protein 1616937..1617281 Escherichia coli ATCC 8739 6067250 YP_001724457.1 CDS EcolC_1467 NC_010468.1 1617285 1618874 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_0899 putative ATP-binding component of a transport system; ABC transporter-like protein complement(1617285..1618874) Escherichia coli ATCC 8739 6067246 YP_001724458.1 CDS EcolC_1468 NC_010468.1 1618876 1619901 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_2145 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein complement(1618876..1619901) Escherichia coli ATCC 8739 6067242 YP_001724459.1 CDS EcolC_1469 NC_010468.1 1619901 1620995 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2234 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein complement(1619901..1620995) Escherichia coli ATCC 8739 6067239 YP_001724460.1 CDS EcolC_1470 NC_010468.1 1620996 1622810 R PFAM: extracellular solute-binding protein family 5; KEGG: sdy:SDY_0902 hypothetical protein; extracellular solute-binding protein complement(1620996..1622810) Escherichia coli ATCC 8739 6067227 YP_001724461.1 CDS EcolC_1471 NC_010468.1 1622892 1624448 R PFAM: EAL domain protein; KEGG: sdy:SDY_0903 hypothetical protein; hypothetical protein complement(1622892..1624448) Escherichia coli ATCC 8739 6067225 YP_001724462.1 CDS spr NC_010468.1 1624629 1625195 R by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein complement(1624629..1625195) Escherichia coli ATCC 8739 6067223 YP_001724463.1 CDS EcolC_1473 NC_010468.1 1625607 1626320 R PFAM: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_2230 hypothetical protein; PA-phosphatase-like phosphoesterase complement(1625607..1626320) Escherichia coli ATCC 8739 6067216 YP_001724464.1 CDS EcolC_1474 NC_010468.1 1626359 1627345 R PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sfx:S2389 hypothetical protein; cobalamin synthesis protein P47K complement(1626359..1627345) Escherichia coli ATCC 8739 6067208 YP_001724465.1 CDS EcolC_1475 NC_010468.1 1627463 1628929 R PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ssn:SSON_2228 putative oxidoreductase; mannitol dehydrogenase domain-containing protein complement(1627463..1628929) Escherichia coli ATCC 8739 6067202 YP_001724466.1 CDS EcolC_1476 NC_010468.1 1629152 1629724 R Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P complement(1629152..1629724) Escherichia coli ATCC 8739 6067193 YP_001724467.1 CDS EcolC_1477 NC_010468.1 1629879 1630133 D PFAM: protein of unknown function UPF0153; KEGG: ent:Ent638_2765 protein of unknown function UPF0153; hypothetical protein 1629879..1630133 Escherichia coli ATCC 8739 6067198 YP_001724468.1 CDS EcolC_1478 NC_010468.1 1630130 1631311 R TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2226 putative transport; sugar efflux transporter complement(1630130..1631311) Escherichia coli ATCC 8739 6067190 YP_001724469.1 CDS EcolC_1479 NC_010468.1 1631679 1632809 D phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 1631679..1632809 Escherichia coli ATCC 8739 6067187 YP_001724470.1 CDS fruK NC_010468.1 1632809 1633747 D converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 1632809..1633747 Escherichia coli ATCC 8739 6067175 YP_001724471.1 CDS EcolC_1481 NC_010468.1 1633764 1635455 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 1633764..1635455 Escherichia coli ATCC 8739 6067169 YP_001724472.1 CDS EcolC_1482 NC_010468.1 1635879 1636820 D PFAM: PfkB domain protein; KEGG: sfv:SFV_2241 putative kinase; hypothetical protein 1635879..1636820 Escherichia coli ATCC 8739 6067167 YP_001724473.1 CDS EcolC_1483 NC_010468.1 1636808 1637746 D PFAM: Indigoidine synthase A family protein; KEGG: sfv:SFV_2240 hypothetical protein; indigoidine synthase A family protein 1636808..1637746 Escherichia coli ATCC 8739 6067153 YP_001724474.1 CDS EcolC_1484 NC_010468.1 1637840 1639090 D TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sfv:SFV_2239 putative transport system permease protein; nucleoside transporter 1637840..1639090 Escherichia coli ATCC 8739 6067149 YP_001724475.1 CDS EcolC_1485 NC_010468.1 1639161 1639820 R activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL complement(1639161..1639820) Escherichia coli ATCC 8739 6067144 YP_001724476.1 CDS rihB NC_010468.1 1639989 1640930 D Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 1639989..1640930 Escherichia coli ATCC 8739 6067145 YP_001724477.1 CDS EcolC_1488 NC_010468.1 1642336 1643424 R PFAM: PfkB domain protein; KEGG: sbo:SBO_2167 putative kinase; hypothetical protein complement(1642336..1643424) Escherichia coli ATCC 8739 6067137 YP_001724478.1 CDS EcolC_1489 NC_010468.1 1643427 1644284 R Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV complement(1643427..1644284) Escherichia coli ATCC 8739 6067135 YP_001724479.1 CDS EcolC_1490 NC_010468.1 1644358 1645407 R PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2169 hypothetical protein; hypothetical protein complement(1644358..1645407) Escherichia coli ATCC 8739 6067130 YP_001724480.1 CDS EcolC_1491 NC_010468.1 1645581 1646387 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_2213 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 1645581..1646387 Escherichia coli ATCC 8739 6067126 YP_001724481.1 CDS EcolC_1492 NC_010468.1 1646592 1648061 D PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2110 lysine-specific permease; lysine transporter 1646592..1648061 Escherichia coli ATCC 8739 6067124 YP_001724482.1 CDS EcolC_1493 NC_010468.1 1648355 1650346 D Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 1648355..1650346 Escherichia coli ATCC 8739 6067120 YP_001724483.1 CDS EcolC_1494 NC_010468.1 1650378 1651214 R KEGG: sbo:SBO_2173 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; S-formylglutathione hydrolase complement(1650378..1651214) Escherichia coli ATCC 8739 6067116 YP_001724484.1 CDS folE NC_010468.1 1651472 1652140 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1651472..1652140 Escherichia coli ATCC 8739 6067118 YP_001724485.1 CDS EcolC_1496 NC_010468.1 1652157 1653314 D PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: sbo:SBO_2175 hypothetical protein; hypothetical protein 1652157..1653314 Escherichia coli ATCC 8739 6067114 YP_001724486.1 CDS EcolC_1497 NC_010468.1 1653456 1654496 D negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 1653456..1654496 Escherichia coli ATCC 8739 6067110 YP_001724487.1 CDS EcolC_1498 NC_010468.1 1654776 1655774 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sdy:SDY_2130 galactose-binding transport protein; periplasmic binding protein/LacI transcriptional regulator 1654776..1655774 Escherichia coli ATCC 8739 6067108 YP_001724488.1 CDS EcolC_1499 NC_010468.1 1655835 1657355 D with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1655835..1657355 Escherichia coli ATCC 8739 6067106 YP_001724489.1 CDS mglC NC_010468.1 1657371 1658381 D ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 1657371..1658381 Escherichia coli ATCC 8739 6067097 YP_001724490.1 CDS EcolC_1501 NC_010468.1 1658452 1659687 R catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase complement(1658452..1659687) Escherichia coli ATCC 8739 6067096 YP_001724491.1 CDS EcolC_1502 NC_010468.1 1659681 1660919 R function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase complement(1659681..1660919) Escherichia coli ATCC 8739 6067093 YP_001724492.1 CDS EcolC_1503 NC_010468.1 1661113 1661352 R KEGG: sbo:SBO_0996 hypothetical protein; hypothetical protein complement(1661113..1661352) Escherichia coli ATCC 8739 6067090 YP_001724493.1 CDS EcolC_1504 NC_010468.1 1661355 1662074 R PFAM: protein of unknown function DUF218; KEGG: sdy:SDY_2143 vancomycin sensitivity; hypothetical protein complement(1661355..1662074) Escherichia coli ATCC 8739 6067091 YP_001724494.1 CDS EcolC_1505 NC_010468.1 1662224 1663108 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(1662224..1663108) Escherichia coli ATCC 8739 6067089 YP_001724495.1 CDS EcolC_1506 NC_010468.1 1663238 1663933 R PFAM: LrgB family protein; KEGG: ssn:SSON_2198 putative seritonin transporter; hypothetical protein complement(1663238..1663933) Escherichia coli ATCC 8739 6067079 YP_001724496.1 CDS EcolC_1507 NC_010468.1 1663930 1664328 R PFAM: LrgA family protein; KEGG: sbo:SBO_1000 hypothetical protein; hypothetical protein complement(1663930..1664328) Escherichia coli ATCC 8739 6067072 YP_001724497.1 CDS EcolC_1508 NC_010468.1 1664567 1665514 D PFAM: dihydrouridine synthase DuS; KEGG: ssn:SSON_2196 putative regulator protein; tRNA-dihydrouridine synthase C 1664567..1665514 Escherichia coli ATCC 8739 6067069 YP_001724498.1 CDS EcolC_1509 NC_010468.1 1666194 1667630 D may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 1666194..1667630 Escherichia coli ATCC 8739 6067066 YP_001724499.1 CDS EcolC_1510 NC_010468.1 1667683 1668444 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbo:SBO_1007 putative oxidoreductase; acetoin dehydrogenase 1667683..1668444 Escherichia coli ATCC 8739 6067065 YP_001724500.1 CDS EcolC_1511 NC_010468.1 1668574 1669152 R PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_1008 hypothetical protein; hypothetical protein complement(1668574..1669152) Escherichia coli ATCC 8739 6067036 YP_001724501.1 CDS EcolC_1512 NC_010468.1 1669322 1669909 D PFAM: protein of unknown function DUF1282; KEGG: sbo:SBO_1009 hypothetical protein; hypothetical protein 1669322..1669909 Escherichia coli ATCC 8739 6067020 YP_001724502.1 CDS pbpG NC_010468.1 1670074 1671015 D specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 1670074..1671015 Escherichia coli ATCC 8739 6067025 YP_001724503.1 CDS EcolC_1514 NC_010468.1 1671053 1672768 R component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase complement(1671053..1672768) Escherichia coli ATCC 8739 6067019 YP_001724504.1 CDS EcolC_1515 NC_010468.1 1672964 1675261 D PFAM: glycoside hydrolase family 3 domain protein; KEGG: ssn:SSON_2189 beta-D-glucoside glucohydrolase, periplasmic; glycoside hydrolase family protein 1672964..1675261 Escherichia coli ATCC 8739 6067004 YP_001724505.1 CDS EcolC_1516 NC_010468.1 1675513 1676430 D PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ssn:SSON_2188 putative transport system permease protein; glycine betaine ABC transporter substrate-binding protein 1675513..1676430 Escherichia coli ATCC 8739 6066985 YP_001724506.1 CDS EcolC_1517 NC_010468.1 1676437 1677594 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2187 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 1676437..1677594 Escherichia coli ATCC 8739 6066963 YP_001724507.1 CDS EcolC_1518 NC_010468.1 1677587 1678513 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_2186 putative ATP-binding component of a transport system; ABC transporter-like protein 1677587..1678513 Escherichia coli ATCC 8739 6066934 YP_001724508.1 CDS EcolC_1519 NC_010468.1 1678518 1679249 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_2185 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 1678518..1679249 Escherichia coli ATCC 8739 6066933 YP_001724509.1 CDS EcolC_1520 NC_010468.1 1679397 1680128 R PFAM: regulatory protein MerR; KEGG: sdy:SDY_2162 putative transcriptional regulator; MerR family transcriptional regulator complement(1679397..1680128) Escherichia coli ATCC 8739 6066931 YP_001724510.1 CDS EcolC_1521 NC_010468.1 1680350 1682035 D PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: sfx:S2325 putative 2-component sensor protein; signal transduction histidine kinase LytS 1680350..1682035 Escherichia coli ATCC 8739 6066922 YP_001724511.1 CDS EcolC_1522 NC_010468.1 1682032 1682751 D unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 1682032..1682751 Escherichia coli ATCC 8739 6066924 YP_001724512.1 CDS EcolC_1523 NC_010468.1 1682798 1683268 D PFAM: protein of unknown function DUF1456; KEGG: sdy:SDY_2165 hypothetical protein; hypothetical protein 1682798..1683268 Escherichia coli ATCC 8739 6066269 YP_001724513.1 CDS EcolC_1524 NC_010468.1 1683309 1683770 R PFAM: protein of unknown function DUF1307; KEGG: ssn:SSON_2169 hypothetical protein; hypothetical protein complement(1683309..1683770) Escherichia coli ATCC 8739 6066913 YP_001724514.1 CDS EcolC_1525 NC_010468.1 1683895 1685898 R PFAM: zinc finger SWIM domain protein; KEGG: sfx:S2316 hypothetical protein; zinc finger SWIM domain-containing protein complement(1683895..1685898) Escherichia coli ATCC 8739 6066782 YP_001724515.1 CDS EcolC_1528 NC_010468.1 1687024 1689303 R KEGG: sfl:SF2189 hypothetical protein; hypothetical protein complement(1687024..1689303) Escherichia coli ATCC 8739 6066616 YP_001724516.1 CDS EcolC_1529 NC_010468.1 1689314 1690402 R PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: sfx:S2313 hypothetical protein; ATPase complement(1689314..1690402) Escherichia coli ATCC 8739 6066532 YP_001724517.1 CDS EcolC_1530 NC_010468.1 1690709 1691026 R KEGG: sfl:SF2187 hypothetical protein; hypothetical protein complement(1690709..1691026) Escherichia coli ATCC 8739 6065917 YP_001724518.1 CDS EcolC_1531 NC_010468.1 1691087 1694719 R KEGG: sbo:SBO_0938 putative regulator; putative regulator complement(1691087..1694719) Escherichia coli ATCC 8739 6065902 YP_001724519.1 CDS EcolC_1532 NC_010468.1 1694729 1698523 R PFAM: WGR domain protein; KEGG: sbo:SBO_0937 putative regulator (fragment); WGR domain-containing protein complement(1694729..1698523) Escherichia coli ATCC 8739 6065895 YP_001724520.1 CDS metG NC_010468.1 1698664 1700697 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1698664..1700697) Escherichia coli ATCC 8739 6065859 YP_001724521.1 CDS EcolC_1534 NC_010468.1 1700829 1701938 D KEGG: sfv:SFV_2169 putative ATPase; putative ATPase 1700829..1701938 Escherichia coli ATCC 8739 6065824 YP_001724522.1 CDS EcolC_1535 NC_010468.1 1702201 1702482 D KEGG: ssn:SSON_2161 hypothetical protein; hypothetical protein 1702201..1702482 Escherichia coli ATCC 8739 6065802 YP_001724523.1 CDS EcolC_1536 NC_010468.1 1702775 1703317 D PFAM: Fimbrial protein; KEGG: ssn:SSON_2160 putative fimbrial-like protein; fimbrial protein 1702775..1703317 Escherichia coli ATCC 8739 6065805 YP_001724524.1 CDS EcolC_1537 NC_010468.1 1703397 1704071 D PFAM: pili assembly chaperone; KEGG: ssn:SSON_2159 putative chaperone; pili assembly chaperone 1703397..1704071 Escherichia coli ATCC 8739 6065795 YP_001724525.1 CDS EcolC_1538 NC_010468.1 1704087 1706567 D PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfv:SFV_2164 putative outer membrane protein; fimbrial biogenesis outer membrane usher protein 1704087..1706567 Escherichia coli ATCC 8739 6065778 YP_001724526.1 CDS EcolC_1539 NC_010468.1 1706583 1707617 D KEGG: ssn:SSON_2156 putative type-1 fimbrial protein; putative type-1 fimbrial protein 1706583..1707617 Escherichia coli ATCC 8739 6065749 YP_001724527.1 CDS EcolC_1540 NC_010468.1 1707699 1708037 R KEGG: ssn:SSON_2155 hypothetical protein; hypothetical protein complement(1707699..1708037) Escherichia coli ATCC 8739 6065716 YP_001724528.1 CDS EcolC_1541 NC_010468.1 1708256 1709080 R membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA complement(1708256..1709080) Escherichia coli ATCC 8739 6065685 YP_001724529.1 CDS EcolC_1542 NC_010468.1 1709201 1709473 D PFAM: protein of unknown function DUF156; KEGG: sdy:SDY_2279 hypothetical protein; hypothetical protein 1709201..1709473 Escherichia coli ATCC 8739 6065636 YP_001724530.1 CDS EcolC_1543 NC_010468.1 1709696 1710484 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 1709696..1710484 Escherichia coli ATCC 8739 6065564 YP_001724531.1 CDS EcolC_1544 NC_010468.1 1710481 1711281 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1710481..1711281 Escherichia coli ATCC 8739 6065473 YP_001724532.1 CDS EcolC_1545 NC_010468.1 1711346 1712164 D PFAM: glycoside hydrolase family 25; KEGG: sbo:SBO_0923 hypothetical protein; glycoside hydrolase family protein 1711346..1712164 Escherichia coli ATCC 8739 6065408 YP_001724533.1 CDS EcolC_1546 NC_010468.1 1712216 1712962 D PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sdy:SDY_2274 putative transcriptional regulator; GntR family transcriptional regulator 1712216..1712962 Escherichia coli ATCC 8739 6065407 YP_001724534.1 CDS EcolC_1548 NC_010468.1 1713898 1714902 R PFAM: ADP-ribosylation/Crystallin J1; KEGG: ssn:SSON_2147 hypothetical protein; ADP-ribosylation/crystallin J1 complement(1713898..1714902) Escherichia coli ATCC 8739 6065385 YP_001724535.1 CDS EcolC_1549 NC_010468.1 1714899 1716176 R TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_2146 putative nucleoside permease protein; nucleoside transporter complement(1714899..1716176) Escherichia coli ATCC 8739 6065367 YP_001724536.1 CDS EcolC_1550 NC_010468.1 1716433 1717485 D catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 1716433..1717485 Escherichia coli ATCC 8739 6065379 YP_001724537.1 CDS gatY NC_010468.1 1717793 1718647 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 1717793..1718647 Escherichia coli ATCC 8739 6065355 YP_001724538.1 CDS EcolC_1552 NC_010468.1 1718676 1719938 D KEGG: sfv:SFV_2150 putative tagatose 6-phosphate kinase 1; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; D-tagatose-bisphosphate aldolase non-catalytic subunit 1718676..1719938 Escherichia coli ATCC 8739 6065315 YP_001724539.1 CDS EcolC_1553 NC_010468.1 1719948 1720400 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 1719948..1720400 Escherichia coli ATCC 8739 6065296 YP_001724540.1 CDS EcolC_1554 NC_010468.1 1720431 1720715 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 1720431..1720715 Escherichia coli ATCC 8739 6065275 YP_001724541.1 CDS EcolC_1555 NC_010468.1 1720719 1722074 D TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: ssn:SSON_2139 PTS system galactitol-specific enzyme IIC; PTS system galactitol-specific transporter subunit IIC 1720719..1722074 Escherichia coli ATCC 8739 6065268 YP_001724542.1 CDS EcolC_1556 NC_010468.1 1722122 1723162 D Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 1722122..1723162 Escherichia coli ATCC 8739 6067349 YP_001724543.1 CDS EcolC_1557 NC_010468.1 1723268 1724041 D PFAM: regulatory protein DeoR; KEGG: ssn:SSON_2137 galactitol utilization operon repressor; DeoR family transcriptional regulator 1723268..1724041 Escherichia coli ATCC 8739 6068255 YP_001724544.1 CDS EcolC_1558 NC_010468.1 1724123 1725022 R cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase complement(1724123..1725022) Escherichia coli ATCC 8739 6067569 YP_001724545.1 CDS EcolC_1559 NC_010468.1 1725428 1725745 D KEGG: sbo:SBO_0909 hypothetical protein; hypothetical protein 1725428..1725745 Escherichia coli ATCC 8739 6064436 YP_001724546.1 CDS EcolC_1560 NC_010468.1 1726076 1727437 R PFAM: peptidase U32; KEGG: ssn:SSON_2134 hypothetical protein; peptidase U32 complement(1726076..1727437) Escherichia coli ATCC 8739 6066531 YP_001724547.1 CDS EcolC_1561 NC_010468.1 1727584 1727916 R PFAM: protein of unknown function DUF1508; KEGG: sbo:SBO_0906 hypothetical protein; hypothetical protein complement(1727584..1727916) Escherichia coli ATCC 8739 6066173 YP_001724548.1 CDS EcolC_1562 NC_010468.1 1728107 1728829 R response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR complement(1728107..1728829) Escherichia coli ATCC 8739 6065054 YP_001724549.1 CDS EcolC_1563 NC_010468.1 1728826 1730229 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sfv:SFV_2139 sensor protein (for BaeR); signal transduction histidine-protein kinase BaeS complement(1728826..1730229) Escherichia coli ATCC 8739 6065479 YP_001724550.1 CDS EcolC_1564 NC_010468.1 1730226 1731641 R PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S2267 putative transport protein; multidrug efflux system protein MdtE complement(1730226..1731641) Escherichia coli ATCC 8739 6065361 YP_001724551.1 CDS EcolC_1565 NC_010468.1 1731642 1734719 R Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC complement(1731642..1734719) Escherichia coli ATCC 8739 6067361 YP_001724552.1 CDS EcolC_1566 NC_010468.1 1734720 1737842 R Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB complement(1734720..1737842) Escherichia coli ATCC 8739 6066374 YP_001724553.1 CDS EcolC_1567 NC_010468.1 1737842 1739209 R Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA complement(1737842..1739209) Escherichia coli ATCC 8739 6065883 YP_001724554.1 CDS EcolC_1568 NC_010468.1 1739977 1740636 D PFAM: von Willebrand factor type A; KEGG: sbo:SBO_0899 hypothetical protein; von Willebrand factor type A 1739977..1740636 Escherichia coli ATCC 8739 6065221 YP_001724555.1 CDS EcolC_1569 NC_010468.1 1740633 1741394 D KEGG: ssn:SSON_2124 hypothetical protein; hypothetical protein 1740633..1741394 Escherichia coli ATCC 8739 6066976 YP_001724556.1 CDS EcolC_1570 NC_010468.1 1741547 1742244 D PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein join(1741547..1741801,1741801..1742244) Escherichia coli ATCC 8739 6065156 YP_001724557.1 CDS EcolC_1571 NC_010468.1 1742271 1744178 D KEGG: ssn:SSON_2123 putative chaperonin; putative chaperonin 1742271..1744178 Escherichia coli ATCC 8739 6066550 YP_001724558.1 CDS EcolC_1572 NC_010468.1 1744190 1745542 R KEGG: sbo:SBO_0896 putative heat shock protein; putative chaperone complement(1744190..1745542) Escherichia coli ATCC 8739 6065691 YP_001724559.1 CDS EcolC_1573 NC_010468.1 1745676 1746524 D inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 1745676..1746524 Escherichia coli ATCC 8739 6066214 YP_001724560.1 CDS EcolC_1574 NC_010468.1 1746633 1749950 R contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein complement(1746633..1749950) Escherichia coli ATCC 8739 6065601 YP_001724561.1 CDS EcolC_1575 NC_010468.1 1750268 1750909 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1750268..1750909 Escherichia coli ATCC 8739 6066320 YP_001724562.1 CDS dcd NC_010468.1 1751001 1751582 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1751001..1751582 Escherichia coli ATCC 8739 6066157 YP_001724563.1 CDS EcolC_1577 NC_010468.1 1751604 1753457 D YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein 1751604..1753457 Escherichia coli ATCC 8739 6065405 YP_001724564.1 CDS EcolC_1578 NC_010468.1 1753731 1755314 R PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: sfv:SFV_2122 putative transport protein; integral membrane protein TerC complement(1753731..1755314) Escherichia coli ATCC 8739 6065815 YP_001724565.1 CDS EcolC_1579 NC_010468.1 1755973 1757112 D PFAM: polysaccharide export protein; KEGG: ssn:SSON_2115 putative polysaccharide export protein; polysaccharide export protein 1755973..1757112 Escherichia coli ATCC 8739 6067139 YP_001724566.1 CDS EcolC_1580 NC_010468.1 1757118 1757561 D Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 1757118..1757561 Escherichia coli ATCC 8739 6065125 YP_001724567.1 CDS EcolC_1581 NC_010468.1 1757564 1759726 D Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 1757564..1759726 Escherichia coli ATCC 8739 6064913 YP_001724568.1 CDS EcolC_1582 NC_010468.1 1759819 1760658 D PFAM: glycosyl transferase family 2; KEGG: sbo:SBO_0886 putative regulator; putative glycosyl transferase 1759819..1760658 Escherichia coli ATCC 8739 6065990 YP_001724569.1 CDS EcolC_1583 NC_010468.1 1760661 1761149 D acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB 1760661..1761149 Escherichia coli ATCC 8739 6066799 YP_001724570.1 CDS EcolC_1584 NC_010468.1 1761146 1762363 D KEGG: sbo:SBO_0884 putative glycosyl transferase; putative glycosyl transferase 1761146..1762363 Escherichia coli ATCC 8739 6066497 YP_001724571.1 CDS wcaD NC_010468.1 1762338 1763555 D essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 1762338..1763555 Escherichia coli ATCC 8739 6067031 YP_001724572.1 CDS EcolC_1586 NC_010468.1 1763566 1764312 D PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_2108 putative colanic acid biosynthesis glycosyl transferase; putative glycosyl transferase 1763566..1764312 Escherichia coli ATCC 8739 6066345 YP_001724573.1 CDS EcolC_1587 NC_010468.1 1764453 1765001 D acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF 1764453..1765001 Escherichia coli ATCC 8739 6066314 YP_001724574.1 CDS EcolC_1588 NC_010468.1 1765027 1766148 D TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_0880 GDP-D-mannose dehydratase; GDP-mannose 4,6-dehydratase 1765027..1766148 Escherichia coli ATCC 8739 6064971 YP_001724575.1 CDS EcolC_1589 NC_010468.1 1766151 1767116 D PFAM: NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_0879 putative nucleotide di-P-sugar epimerase; NAD-dependent epimerase/dehydratase 1766151..1767116 Escherichia coli ATCC 8739 6066811 YP_001724576.1 CDS EcolC_1590 NC_010468.1 1767119 1767598 D PFAM: NUDIX hydrolase; KEGG: sfv:SFV_2108 GDP-mannose mannosyl hydrolase; NUDIX hydrolase 1767119..1767598 Escherichia coli ATCC 8739 6064796 YP_001724577.1 CDS EcolC_1591 NC_010468.1 1767595 1768818 D PFAM: glycosyl transferase group 1; KEGG: sfx:S2236 putative colanic biosynthesis glycosyl transferase; putative glycosyl transferase 1767595..1768818 Escherichia coli ATCC 8739 6065933 YP_001724578.1 CDS EcolC_1592 NC_010468.1 1768821 1770257 D KEGG: ssn:SSON_2102 mannose-1-phosphate guanyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1768821..1770257 Escherichia coli ATCC 8739 6065291 YP_001724579.1 CDS EcolC_1593 NC_010468.1 1770450 1771820 D PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sbo:SBO_0875 phosphomannomutase; phosphomannomutase 1770450..1771820 Escherichia coli ATCC 8739 6064652 YP_001724580.1 CDS EcolC_1594 NC_010468.1 1771875 1773269 D WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase 1771875..1773269 Escherichia coli ATCC 8739 6065279 YP_001724581.1 CDS EcolC_1595 NC_010468.1 1773271 1774749 D PFAM: polysaccharide biosynthesis protein; KEGG: sbo:SBO_0873 probable export protein; colanic acid exporter 1773271..1774749 Escherichia coli ATCC 8739 6065069 YP_001724582.1 CDS EcolC_1596 NC_010468.1 1775025 1776305 D PFAM: polysaccharide pyruvyl transferase; KEGG: sbo:SBO_0872 putative galactokinase; putative pyruvyl transferase 1775025..1776305 Escherichia coli ATCC 8739 6064689 YP_001724583.1 CDS EcolC_1597 NC_010468.1 1776302 1777522 D PFAM: glycosyl transferase group 1; KEGG: sbo:SBO_0871 putative colanic acid biosynthesis glycosyl transferase; group 1 glycosyl transferase 1776302..1777522 Escherichia coli ATCC 8739 6065495 YP_001724584.1 CDS wcaM NC_010468.1 1777533 1778927 D WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein 1777533..1778927 Escherichia coli ATCC 8739 6065621 YP_001724585.1 CDS EcolC_1599 NC_010468.1 1779085 1780080 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: esa:ESA_01176 hypothetical protein; NAD-dependent epimerase/dehydratase 1779085..1780080 Escherichia coli ATCC 8739 6066057 YP_001724586.1 CDS EcolC_1600 NC_010468.1 1780323 1781216 D together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 1780323..1781216 Escherichia coli ATCC 8739 6066055 YP_001724587.1 CDS EcolC_1601 NC_010468.1 1781588 1782673 D NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase 1781588..1782673 Escherichia coli ATCC 8739 6066255 YP_001724588.1 CDS EcolC_1602 NC_010468.1 1782673 1783572 D with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 1782673..1783572 Escherichia coli ATCC 8739 6064868 YP_001724589.1 CDS EcolC_1603 NC_010468.1 1783630 1784508 D TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sbo:SBO_0866 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase 1783630..1784508 Escherichia coli ATCC 8739 6065198 YP_001724590.1 CDS EcolC_1604 NC_010468.1 1784513 1785046 D KEGG: sdy:SDY_2207 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; dTDP-4-dehydrorhamnose 3,5-epimerase 1784513..1785046 Escherichia coli ATCC 8739 6065233 YP_001724591.1 CDS EcolC_1605 NC_010468.1 1785061 1786053 D PFAM: nitroreductase; KEGG: mpt:Mpe_A0731 nitroreductase-like protein; nitroreductase 1785061..1786053 Escherichia coli ATCC 8739 6066186 YP_001724592.1 CDS EcolC_1606 NC_010468.1 1786050 1787588 D KEGG: bfs:BF2791 putative transmembrane protein; putative transmembrane protein 1786050..1787588 Escherichia coli ATCC 8739 6065231 YP_001724593.1 CDS EcolC_1607 NC_010468.1 1787581 1788684 D KEGG: bfs:BF2794 hypothetical protein; hypothetical protein 1787581..1788684 Escherichia coli ATCC 8739 6066178 YP_001724594.1 CDS EcolC_1608 NC_010468.1 1788690 1789832 D PFAM: glycosyl transferase group 1; KEGG: lsl:LSL_0978 glycosyltransferase; group 1 glycosyl transferase 1788690..1789832 Escherichia coli ATCC 8739 6067678 YP_001724595.1 CDS EcolC_1609 NC_010468.1 1789894 1791129 D KEGG: ssp:SSP0069 putative polysaccharide polymerase; hypothetical protein 1789894..1791129 Escherichia coli ATCC 8739 6065241 YP_001724596.1 CDS EcolC_1610 NC_010468.1 1791092 1791979 D PFAM: glycosyl transferase family 2; KEGG: pat:Patl_3205 rhamnosyltransferase; glycosyl transferase family protein 1791092..1791979 Escherichia coli ATCC 8739 6065121 YP_001724597.1 CDS EcolC_1612 NC_010468.1 1792279 1792976 R PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein; insertion element protein complement(join(1792279..1792722,1792722..1792976)) Escherichia coli ATCC 8739 6065827 YP_001724598.1 CDS EcolC_1613 NC_010468.1 1794104 1795510 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1794104..1795510 Escherichia coli ATCC 8739 6067000 YP_001724599.1 CDS EcolC_1614 NC_010468.1 1795759 1796925 D KEGG: ssn:SSON_2099 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; nucleotide sugar dehydrogenase 1795759..1796925 Escherichia coli ATCC 8739 6065807 YP_001724600.1 CDS EcolC_1615 NC_010468.1 1797072 1798052 D PFAM: lipopolysaccharide biosynthesis protein; KEGG: ssn:SSON_2098 regulator of length of O-antigen component of lipopolysaccharide chains; lipopolysaccharide biosynthesis protein 1797072..1798052 Escherichia coli ATCC 8739 6066608 YP_001724601.1 CDS EcolC_1616 NC_010468.1 1798149 1798760 R catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase complement(1798149..1798760) Escherichia coli ATCC 8739 6067233 YP_001724602.1 CDS EcolC_1617 NC_010468.1 1798754 1799530 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(1798754..1799530) Escherichia coli ATCC 8739 6065359 YP_001724603.1 CDS EcolC_1618 NC_010468.1 1799512 1800249 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(1799512..1800249) Escherichia coli ATCC 8739 6066541 YP_001724604.1 CDS hisH NC_010468.1 1800249 1800839 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(1800249..1800839) Escherichia coli ATCC 8739 6066676 YP_001724605.1 CDS EcolC_1620 NC_010468.1 1800839 1801906 R catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase complement(1800839..1801906) Escherichia coli ATCC 8739 6066075 YP_001724606.1 CDS EcolC_1621 NC_010468.1 1801906 1802976 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(1801906..1802976) Escherichia coli ATCC 8739 6066776 YP_001724607.1 CDS hisD NC_010468.1 1802973 1804277 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(1802973..1804277) Escherichia coli ATCC 8739 6066383 YP_001724608.1 CDS hisG NC_010468.1 1804283 1805182 R long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase complement(1804283..1805182) Escherichia coli ATCC 8739 6065987 YP_001724609.1 CDS EcolC_1624 NC_010468.1 1805803 1806627 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ssn:SSON_2086 putative enzyme of sugar metabolism; NAD-dependent epimerase/dehydratase 1805803..1806627 Escherichia coli ATCC 8739 6064968 YP_001724610.1 CDS EcolC_1625 NC_010468.1 1806673 1807602 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_0841 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 1806673..1807602 Escherichia coli ATCC 8739 6065880 YP_001724611.1 CDS EcolC_1626 NC_010468.1 1807869 1809227 D PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2226 putative amino acid/amine transport protein; amino acid permease-associated protein 1807869..1809227 Escherichia coli ATCC 8739 6066151 YP_001724612.1 CDS EcolC_1627 NC_010468.1 1809406 1810464 D PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: ssn:SSON_2083 putative transport system permease protein; hypothetical protein 1809406..1810464 Escherichia coli ATCC 8739 6065324 YP_001724613.1 CDS EcolC_1628 NC_010468.1 1810478 1810705 D PFAM: SirA family protein; KEGG: sbo:SBO_0836 hypothetical protein; SirA family protein 1810478..1810705 Escherichia coli ATCC 8739 6065793 YP_001724614.1 CDS sbcB NC_010468.1 1810748 1812175 R Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I complement(1810748..1812175) Escherichia coli ATCC 8739 6066380 YP_001724615.1 CDS dacD NC_010468.1 1812384 1813550 D removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1812384..1813550 Escherichia coli ATCC 8739 6064760 YP_001724616.1 CDS EcolC_1631 NC_010468.1 1813669 1814142 D PFAM: transcription activator effector binding; KEGG: ssn:SSON_2079 SbmC protein; DNA gyrase inhibitor 1813669..1814142 Escherichia coli ATCC 8739 6067104 YP_001724617.1 CDS EcolC_1632 NC_010468.1 1814341 1815399 D KEGG: ssn:SSON_2078 hypothetical protein; hypothetical protein 1814341..1815399 Escherichia coli ATCC 8739 6065734 YP_001724618.1 CDS EcolC_1633 NC_010468.1 1815571 1815900 D PFAM: protein of unknown function DUF496; KEGG: sbo:SBO_0832 putative alpha helix protein; hypothetical protein 1815571..1815900 Escherichia coli ATCC 8739 6066428 YP_001724619.1 CDS cobU NC_010468.1 1816359 1816904 D catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1816359..1816904 Escherichia coli ATCC 8739 6065129 YP_001724620.1 CDS cobS NC_010468.1 1816901 1817644 D catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1816901..1817644 Escherichia coli ATCC 8739 6065626 YP_001724621.1 CDS cobT NC_010468.1 1817656 1818735 D catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1817656..1818735 Escherichia coli ATCC 8739 6066240 YP_001724622.1 CDS EcolC_1638 NC_010468.1 1818800 1819723 D PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2243 hypothetical protein; hypothetical protein 1818800..1819723 Escherichia coli ATCC 8739 6065643 YP_001724623.1 CDS EcolC_1639 NC_010468.1 1819885 1820862 D PFAM: putative sugar-binding domain protein; KEGG: sco:SCO1463 putative transcriptional regulator; DeoR family transcriptional regulator 1819885..1820862 Escherichia coli ATCC 8739 6065580 YP_001724624.1 CDS EcolC_1640 NC_010468.1 1820914 1821372 R PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: lca:LSEI_2707 phosphotransferase system galactitol-specific IIA domain (Ntr-type); putative PTS IIA-like nitrogen-regulatory protein PtsN complement(1820914..1821372) Escherichia coli ATCC 8739 6066471 YP_001724625.1 CDS EcolC_1641 NC_010468.1 1821383 1821667 R KEGG: sak:SAK_0530 PTS system, galactitol-specific IIB component, putative; PTS system galactitol-specific transporter subunit IIB complement(1821383..1821667) Escherichia coli ATCC 8739 6066803 YP_001724626.1 CDS EcolC_1642 NC_010468.1 1821691 1823061 R PFAM: PTS system Galactitol-specific IIC component; KEGG: tte:TTE0183 PTS system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC complement(1821691..1823061) Escherichia coli ATCC 8739 6064683 YP_001724627.1 CDS EcolC_1643 NC_010468.1 1823065 1823601 R TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; KEGG: aae:aq_1138 ribose 5-phosphate isomerase B; RpiB/LacA/LacB family sugar-phosphate isomerase complement(1823065..1823601) Escherichia coli ATCC 8739 6066584 YP_001724628.1 CDS EcolC_1644 NC_010468.1 1823950 1824705 D PFAM: regulatory protein DeoR; KEGG: bcl:ABC3573 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 1823950..1824705 Escherichia coli ATCC 8739 6065120 YP_001724629.1 CDS EcolC_1645 NC_010468.1 1825033 1825476 D PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: hso:HS_1144 PTS system, galactitol-specific IIA component; putative PTS IIA-like nitrogen-regulatory protein PtsN 1825033..1825476 Escherichia coli ATCC 8739 6065115 YP_001724630.1 CDS EcolC_1646 NC_010468.1 1825495 1825788 D PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: cdf:CD1083 PTS system, IIb component; PTS system lactose/cellobiose-specific transporter subunit IIB 1825495..1825788 Escherichia coli ATCC 8739 6067185 YP_001724631.1 CDS EcolC_1647 NC_010468.1 1825809 1827062 D PFAM: PTS system Galactitol-specific IIC component; KEGG: pac:PPA0022 PTS system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1825809..1827062 Escherichia coli ATCC 8739 6065248 YP_001724632.1 CDS EcolC_1648 NC_010468.1 1827085 1827729 D PFAM: ribulose-phosphate 3-epimerase; KEGG: lmf:LMOf2365_0534 ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 1827085..1827729 Escherichia coli ATCC 8739 6064848 YP_001724633.1 CDS EcolC_1649 NC_010468.1 1827827 1828579 D PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bpu:BPUM_1176 short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 1827827..1828579 Escherichia coli ATCC 8739 6064845 YP_001724634.1 CDS EcolC_1650 NC_010468.1 1828595 1829155 D PFAM: sugar isomerase (SIS); KEGG: bsu:BG11182 6-phospho-3-hexuloisomerase; sugar isomerase (SIS) 1828595..1829155 Escherichia coli ATCC 8739 6066009 YP_001724635.1 CDS EcolC_1651 NC_010468.1 1829696 1833679 D hypothetical protein 1829696..1833679 Escherichia coli ATCC 8739 6065588 YP_001724636.1 CDS EcolC_1652 NC_010468.1 1833672 1835798 D KEGG: plu:plu0532 hypothetical protein; hypothetical protein 1833672..1835798 Escherichia coli ATCC 8739 6066336 YP_001724637.1 CDS EcolC_1653 NC_010468.1 1836693 1840448 R TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(1836693..1840448) Escherichia coli ATCC 8739 6066987 YP_001724638.1 CDS EcolC_1654 NC_010468.1 1840904 1841419 D KEGG: sbo:SBO_1138 hypothetical protein; hypothetical protein 1840904..1841419 Escherichia coli ATCC 8739 6067356 YP_001724639.1 CDS EcolC_1655 NC_010468.1 1842326 1843210 D KEGG: ypk:y3085 hypothetical protein; hypothetical protein 1842326..1843210 Escherichia coli ATCC 8739 6065074 YP_001724640.1 CDS EcolC_1657 NC_010468.1 1846408 1847325 D Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 1846408..1847325 Escherichia coli ATCC 8739 6067292 YP_001724641.1 CDS cbl NC_010468.1 1847427 1848377 D LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 1847427..1848377 Escherichia coli ATCC 8739 6067564 YP_001724642.1 CDS EcolC_1659 NC_010468.1 1848651 1850138 D TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ssn:SSON_2044 hypothetical protein; hypothetical protein 1848651..1850138 Escherichia coli ATCC 8739 6067098 YP_001724643.1 CDS EcolC_1660 NC_010468.1 1850767 1851483 R PFAM: protein of unknown function DUF28; KEGG: sbo:SBO_1217 hypothetical protein; hypothetical protein complement(1850767..1851483) Escherichia coli ATCC 8739 6066477 YP_001724644.1 CDS EcolC_1661 NC_010468.1 1851826 1853280 R Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase complement(1851826..1853280) Escherichia coli ATCC 8739 6064801 YP_001724645.1 CDS EcolC_1662 NC_010468.1 1853382 1854698 R TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2254 putative transport protein, shikimate; shikimate transporter complement(1853382..1854698) Escherichia coli ATCC 8739 6064800 YP_001724646.1 CDS EcolC_1663 NC_010468.1 1855013 1856065 D KEGG: ssn:SSON_2040 hypothetical protein; ADP-heptose--LPS heptosyltransferase-like protein 1855013..1856065 Escherichia coli ATCC 8739 6065698 YP_001724647.1 CDS EcolC_1667 NC_010468.1 1864425 1868024 R TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(1864425..1868024) Escherichia coli ATCC 8739 6065112 YP_001724648.1 CDS EcolC_1668 NC_010468.1 1868927 1869811 D KEGG: ypk:y3085 hypothetical protein; hypothetical protein 1868927..1869811 Escherichia coli ATCC 8739 6066067 YP_001724649.1 CDS EcolC_1670 NC_010468.1 1872721 1873518 R PFAM: protein of unknown function DUF980; KEGG: ssn:SSON_2035 hypothetical protein; hypothetical protein complement(1872721..1873518) Escherichia coli ATCC 8739 6064685 YP_001724650.1 CDS EcolC_1671 NC_010468.1 1874271 1874801 R PFAM: cytochrome B561; KEGG: sbo:SBO_1032 putative cytochrome; cytochrome B561 complement(1874271..1874801) Escherichia coli ATCC 8739 6066686 YP_001724651.1 CDS EcolC_1672 NC_010468.1 1875144 1875815 R PFAM: YodA domain protein; KEGG: sdy:SDY_1033 hypothetical protein; hypothetical protein complement(1875144..1875815) Escherichia coli ATCC 8739 6066765 YP_001724652.1 CDS EcolC_1673 NC_010468.1 1876051 1876686 R in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ complement(1876051..1876686) Escherichia coli ATCC 8739 6066431 YP_001724653.1 CDS EcolC_1674 NC_010468.1 1876687 1877691 R in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY complement(1876687..1877691) Escherichia coli ATCC 8739 6065742 YP_001724654.1 CDS EcolC_1675 NC_010468.1 1877800 1878213 R TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: sfv:SFV_2015 hypothetical protein; hydroxyisourate hydrolase complement(1877800..1878213) Escherichia coli ATCC 8739 6066042 YP_001724655.1 CDS EcolC_1676 NC_010468.1 1878235 1879017 D induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 1878235..1879017 Escherichia coli ATCC 8739 6065461 YP_001724656.1 CDS EcolC_1677 NC_010468.1 1879017 1880375 D TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_2026 putative 2-component sensor protein; heavy metal sensor signal transduction histidine kinase 1879017..1880375 Escherichia coli ATCC 8739 6066865 YP_001724657.1 CDS EcolC_1678 NC_010468.1 1880483 1881334 R Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA complement(1880483..1881334) Escherichia coli ATCC 8739 6066273 YP_001724658.1 CDS EcolC_1679 NC_010468.1 1881927 1883000 R PFAM: porin Gram-negative type; KEGG: spe:Spro_1730 porin gram-negative type; porin complement(1881927..1883000) Escherichia coli ATCC 8739 6064939 YP_001724659.1 CDS EcolC_1680 NC_010468.1 1883549 1883932 D KEGG: sbo:SBO_1045 hypothetical protein; hypothetical protein 1883549..1883932 Escherichia coli ATCC 8739 6065649 YP_001724660.1 CDS EcolC_1681 NC_010468.1 1883972 1884667 D PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbo:SBO_1046 hypothetical protein; hypothetical protein 1883972..1884667 Escherichia coli ATCC 8739 6065958 YP_001724661.1 CDS EcolC_1682 NC_010468.1 1884734 1886152 D TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ssn:SSON_2018 DNA cytosine methylase; DNA cytosine methylase 1884734..1886152 Escherichia coli ATCC 8739 6066519 YP_001724662.1 CDS EcolC_1683 NC_010468.1 1886133 1886603 D TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: sdy:SDY_1046 DNA mismatch endonuclease, patch repair protein; DNA mismatch endonuclease Vsr 1886133..1886603 Escherichia coli ATCC 8739 6064609 YP_001724663.1 CDS EcolC_1684 NC_010468.1 1886592 1887512 R TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_1049 putative transmembrane subunit; hypothetical protein complement(1886592..1887512) Escherichia coli ATCC 8739 6066642 YP_001724664.1 CDS EcolC_1685 NC_010468.1 1887685 1888602 D PFAM: protein of unknown function DUF808; KEGG: sdy:SDY_1048 hypothetical protein; hypothetical protein 1887685..1888602 Escherichia coli ATCC 8739 6065428 YP_001724665.1 CDS EcolC_1686 NC_010468.1 1888681 1888863 D KEGG: sdy:SDY_1049 hypothetical protein; hypothetical protein 1888681..1888863 Escherichia coli ATCC 8739 6066448 YP_001724666.1 CDS EcolC_1687 NC_010468.1 1889101 1890795 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_2013 hypothetical protein; diguanylate cyclase 1889101..1890795 Escherichia coli ATCC 8739 6065583 YP_001724667.1 CDS EcolC_1688 NC_010468.1 1890792 1891607 R catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase complement(1890792..1891607) Escherichia coli ATCC 8739 6066364 YP_001724668.1 CDS EcolC_1689 NC_010468.1 1891905 1892132 R KEGG: sdy:SDY_1052 hypothetical protein; hypothetical protein complement(1891905..1892132) Escherichia coli ATCC 8739 6064869 YP_001724669.1 CDS EcolC_1690 NC_010468.1 1892295 1892483 D KEGG: sdy:SDY_1053 hypothetical protein; hypothetical protein 1892295..1892483 Escherichia coli ATCC 8739 6065955 YP_001724670.1 CDS EcolC_1691 NC_010468.1 1892527 1893150 R PFAM: regulatory protein LuxR; KEGG: sbo:SBO_1056 positive regulator for ctr capsule biosynthesis, positive transcription factor; LuxR family transcriptional regulator complement(1892527..1893150) Escherichia coli ATCC 8739 6064920 YP_001724671.1 CDS fliR NC_010468.1 1893440 1894225 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(1893440..1894225) Escherichia coli ATCC 8739 6065259 YP_001724672.1 CDS fliQ NC_010468.1 1894234 1894503 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(1894234..1894503) Escherichia coli ATCC 8739 6065545 YP_001724673.1 CDS fliP NC_010468.1 1894513 1895250 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(1894513..1895250) Escherichia coli ATCC 8739 6066908 YP_001724674.1 CDS EcolC_1695 NC_010468.1 1895250 1895615 R with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO complement(1895250..1895615) Escherichia coli ATCC 8739 6065692 YP_001724675.1 CDS fliN NC_010468.1 1895618 1896031 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN complement(1895618..1896031) Escherichia coli ATCC 8739 6066071 YP_001724676.1 CDS fliM NC_010468.1 1896028 1897032 R with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM complement(1896028..1897032) Escherichia coli ATCC 8739 6064611 YP_001724677.1 CDS fliL NC_010468.1 1897037 1897501 R interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL complement(1897037..1897501) Escherichia coli ATCC 8739 6066719 YP_001724678.1 CDS EcolC_1699 NC_010468.1 1897606 1898733 R PFAM: flagellar hook-length control protein; KEGG: sfv:SFV_1986 flagellar hook-length control protein; flagellar hook-length control protein complement(1897606..1898733) Escherichia coli ATCC 8739 6066712 YP_001724679.1 CDS fliJ NC_010468.1 1898730 1899173 R rod/hook and filament chaperone; flagellar biosynthesis chaperone complement(1898730..1899173) Escherichia coli ATCC 8739 6065422 YP_001724680.1 CDS fliI NC_010468.1 1899192 1900565 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(1899192..1900565) Escherichia coli ATCC 8739 6065421 YP_001724681.1 CDS fliH NC_010468.1 1900565 1901251 R binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H complement(1900565..1901251) Escherichia coli ATCC 8739 6066728 YP_001724682.1 CDS fliG NC_010468.1 1901244 1902239 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G complement(1901244..1902239) Escherichia coli ATCC 8739 6064630 YP_001724683.1 CDS fliF NC_010468.1 1902232 1903890 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein complement(1902232..1903890) Escherichia coli ATCC 8739 6064603 YP_001724684.1 CDS fliE NC_010468.1 1904105 1904419 D forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1904105..1904419 Escherichia coli ATCC 8739 6065308 YP_001724685.1 CDS EcolC_1708 NC_010468.1 1905980 1906651 R PFAM: protein of unknown function DUF159; KEGG: sdy:SDY_1084 hypothetical protein; hypothetical protein complement(1905980..1906651) Escherichia coli ATCC 8739 6066853 YP_001724686.1 CDS EcolC_1709 NC_010468.1 1906758 1906991 R PFAM: SirA family protein; KEGG: cko:CKO_01008 hypothetical protein; hypothetical protein complement(1906758..1906991) Escherichia coli ATCC 8739 6065451 YP_001724687.1 CDS EcolC_1710 NC_010468.1 1906988 1908193 R PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: sbo:SBO_1077 putative transport system permease protein; putative inner membrane protein complement(1906988..1908193) Escherichia coli ATCC 8739 6065338 YP_001724688.1 CDS EcolC_1711 NC_010468.1 1908380 1908793 D KEGG: sdy:SDY_1087 hypothetical protein; hypothetical protein 1908380..1908793 Escherichia coli ATCC 8739 6067465 YP_001724689.1 CDS EcolC_1712 NC_010468.1 1908827 1910314 R converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase complement(1908827..1910314) Escherichia coli ATCC 8739 6066299 YP_001724690.1 CDS EcolC_1713 NC_010468.1 1910392 1910757 R binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT complement(1910392..1910757) Escherichia coli ATCC 8739 6065840 YP_001724691.1 CDS fliS NC_010468.1 1910757 1911167 R flagellin specific chaperone; flagellar protein FliS complement(1910757..1911167) Escherichia coli ATCC 8739 6066437 YP_001724692.1 CDS fliD NC_010468.1 1911192 1912598 R involved in flagellin assembly; flagellar capping protein complement(1911192..1912598) Escherichia coli ATCC 8739 6067457 YP_001724693.1 CDS EcolC_1716 NC_010468.1 1912864 1914582 D structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 1912864..1914582 Escherichia coli ATCC 8739 6065051 YP_001724694.1 CDS fliA NC_010468.1 1914902 1915621 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1914902..1915621 Escherichia coli ATCC 8739 6066652 YP_001724695.1 CDS EcolC_1718 NC_010468.1 1915667 1916218 D expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1915667..1916218 Escherichia coli ATCC 8739 6067320 YP_001724696.1 CDS EcolC_1719 NC_010468.1 1916249 1917106 D PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: sfl:SF1963 putative periplasmic binding transport protein; cystine transporter subunit 1916249..1917106 Escherichia coli ATCC 8739 6065148 YP_001724697.1 CDS EcolC_1720 NC_010468.1 1917211 1918197 D catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1917211..1918197 Escherichia coli ATCC 8739 6067313 YP_001724698.1 CDS EcolC_1721 NC_010468.1 1918212 1918880 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1200 putative transport system permease protein (former YecC); polar amino acid ABC transporter inner membrane protein 1918212..1918880 Escherichia coli ATCC 8739 6066856 YP_001724699.1 CDS EcolC_1722 NC_010468.1 1918877 1919629 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_1201 putative ATP-binding component of a transport system; putative amino-acid ABC transporter ATP-binding protein YecC 1918877..1919629 Escherichia coli ATCC 8739 6067496 YP_001724700.1 CDS EcolC_1723 NC_010468.1 1919859 1920581 D regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 1919859..1920581 Escherichia coli ATCC 8739 6066493 YP_001724701.1 CDS EcolC_1724 NC_010468.1 1920649 1920873 R KEGG: sdy:SDY_1103 hypothetical protein; hypothetical protein complement(1920649..1920873) Escherichia coli ATCC 8739 6065297 YP_001724702.1 CDS EcolC_1725 NC_010468.1 1921332 1921988 D in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1921332..1921988 Escherichia coli ATCC 8739 6067209 YP_001724703.1 CDS uvrC NC_010468.1 1921985 1923817 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1921985..1923817 Escherichia coli ATCC 8739 6067201 YP_001724704.1 CDS EcolC_1727 NC_010468.1 1923874 1924422 D KEGG: sdy:SDY_1106 phosphatidylglycerophosphate synthetase CDP-1,2-diacyl-sn-glycero-3-phosphate phosphatidyl transferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; phosphatidylglycerophosphate synthetase 1923874..1924422 Escherichia coli ATCC 8739 6067189 YP_001724705.1 CDS EcolC_1728 NC_010468.1 1925071 1925736 D TIGRFAM: yecA family protein; PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1098 hypothetical protein; hypothetical protein 1925071..1925736 Escherichia coli ATCC 8739 6067082 YP_001724706.1 CDS EcolC_1729 NC_010468.1 1925798 1927009 R TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ssn:SSON_1211 tyrosine-specific transport system; aromatic amino acid transporter complement(1925798..1927009) Escherichia coli ATCC 8739 6067012 YP_001724707.1 CDS EcolC_1730 NC_010468.1 1927199 1927438 D KEGG: sfv:SFV_1950 hypothetical protein; hypothetical protein 1927199..1927438 Escherichia coli ATCC 8739 6066925 YP_001724708.1 CDS EcolC_1731 NC_010468.1 1927476 1927973 R cytoplasmic iron storage protein; ferritin complement(1927476..1927973) Escherichia coli ATCC 8739 6066920 YP_001724709.1 CDS EcolC_1732 NC_010468.1 1928145 1928468 R KEGG: sdy:SDY_1114 hypothetical protein; hypothetical protein complement(1928145..1928468) Escherichia coli ATCC 8739 6066634 YP_001724710.1 CDS EcolC_1733 NC_010468.1 1929262 1929765 R PFAM: Ferritin Dps family protein; KEGG: sdy:SDY_1116 ferritin-like protein; ferritin Dps family protein complement(1929262..1929765) Escherichia coli ATCC 8739 6066192 YP_001724711.1 CDS EcolC_1734 NC_010468.1 1930562 1931551 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ssn:SSON_1217 L-arabinose-binding periplasmic protein; monosaccharide-transporting ATPase 1930562..1931551 Escherichia coli ATCC 8739 6065782 YP_001724712.1 CDS araG NC_010468.1 1931621 1933135 D Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1931621..1933135 Escherichia coli ATCC 8739 6065634 YP_001724713.1 CDS araH NC_010468.1 1933150 1934136 D Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1933150..1934136 Escherichia coli ATCC 8739 6065478 YP_001724714.1 CDS EcolC_1737 NC_010468.1 1934303 1935103 D biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1934303..1935103 Escherichia coli ATCC 8739 6065382 YP_001724715.1 CDS EcolC_1738 NC_010468.1 1935078 1936502 D KEGG: sdy:SDY_1193 trehalose-6-phosphate synthase; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; PFAM: glycosyl transferase family 20; trehalose-6-phosphate synthase 1935078..1936502 Escherichia coli ATCC 8739 6065352 YP_001724716.1 CDS EcolC_1739 NC_010468.1 1936509 1936937 R ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC complement(1936509..1936937) Escherichia coli ATCC 8739 6068740 YP_001724717.1 CDS EcolC_1740 NC_010468.1 1937716 1938066 D with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1937716..1938066 Escherichia coli ATCC 8739 6064752 YP_001724718.1 CDS EcolC_1741 NC_010468.1 1938069 1938647 D With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1938069..1938647 Escherichia coli ATCC 8739 6067663 YP_001724719.1 CDS EcolC_1742 NC_010468.1 1938774 1939661 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1938774..1939661 Escherichia coli ATCC 8739 6065298 YP_001724720.1 CDS motB NC_010468.1 1939658 1940584 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1939658..1940584 Escherichia coli ATCC 8739 6064766 YP_001724721.1 CDS EcolC_1744 NC_010468.1 1940589 1942553 D chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1940589..1942553 Escherichia coli ATCC 8739 6066410 YP_001724722.1 CDS EcolC_1745 NC_010468.1 1942574 1943077 D PFAM: CheW domain protein; KEGG: ssn:SSON_1230 positive regulator of CheA protein activity; purine-binding chemotaxis protein 1942574..1943077 Escherichia coli ATCC 8739 6066862 YP_001724723.1 CDS EcolC_1746 NC_010468.1 1943222 1944883 D PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ssn:SSON_1231 methyl-accepting chemotaxis protein II; methyl-accepting chemotaxis sensory transducer 1943222..1944883 Escherichia coli ATCC 8739 6065930 YP_001724724.1 CDS EcolC_1747 NC_010468.1 1944929 1946530 D mediates taxis toward dipeptides; methyl-accepting protein IV 1944929..1946530 Escherichia coli ATCC 8739 6065952 YP_001724725.1 CDS EcolC_1748 NC_010468.1 1946549 1947409 D methylates the MCP; chemotaxis methyltransferase CheR 1946549..1947409 Escherichia coli ATCC 8739 6066325 YP_001724726.1 CDS EcolC_1749 NC_010468.1 1947412 1948461 D regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1947412..1948461 Escherichia coli ATCC 8739 6066189 YP_001724727.1 CDS EcolC_1750 NC_010468.1 1948476 1948865 D chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1948476..1948865 Escherichia coli ATCC 8739 6067360 YP_001724728.1 CDS EcolC_1751 NC_010468.1 1948876 1949520 D cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1948876..1949520 Escherichia coli ATCC 8739 6066182 YP_001724729.1 CDS flhB NC_010468.1 1949722 1950870 D membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1949722..1950870 Escherichia coli ATCC 8739 6065327 YP_001724730.1 CDS flhA NC_010468.1 1950863 1952941 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1950863..1952941 Escherichia coli ATCC 8739 6065810 YP_001724731.1 CDS EcolC_1754 NC_010468.1 1952941 1953333 D PFAM: flagellar FlhE family protein; KEGG: sbo:SBO_1122 flagellar protein; flagellar FlhE family protein 1952941..1953333 Escherichia coli ATCC 8739 6066161 YP_001724732.1 CDS EcolC_1755 NC_010468.1 1953454 1953942 R PFAM: protein of unknown function DUF1311; KEGG: sbo:SBO_1123 hypothetical protein; hypothetical protein complement(1953454..1953942) Escherichia coli ATCC 8739 6065258 YP_001724733.1 CDS argS NC_010468.1 1954119 1955852 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(1954119..1955852) Escherichia coli ATCC 8739 6066595 YP_001724734.1 CDS EcolC_1757 NC_010468.1 1956068 1956634 D PFAM: protein of unknown function DUF991; KEGG: sdy:SDY_1179 hypothetical protein; hypothetical protein 1956068..1956634 Escherichia coli ATCC 8739 6066474 YP_001724735.1 CDS EcolC_1758 NC_010468.1 1956648 1957394 D PFAM: CutC family protein; KEGG: sbo:SBO_1126 copper homeostasis protein; copper homeostasis protein CutC 1956648..1957394 Escherichia coli ATCC 8739 6065670 YP_001724736.1 CDS EcolC_1759 NC_010468.1 1957782 1958882 D PFAM: NapC/NirT cytochrome c domain protein; KEGG: sfv:SFV_1911 putative cytochrome c-type protein; NapC/NirT cytochrome c domain-containing protein 1957782..1958882 Escherichia coli ATCC 8739 6066598 YP_001724737.1 CDS EcolC_1760 NC_010468.1 1958907 1961336 D TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfx:S2003 biotin sulfoxide reductase 2; molybdopterin guanine dinucleotide-containing S/N-oxide reductase 1958907..1961336 Escherichia coli ATCC 8739 6065343 YP_001724738.1 CDS EcolC_1761 NC_010468.1 1961501 1962472 R TIGRFAM: methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; KEGG: sdy:SDY_1170 putative enzyme; methyltransferase complement(1961501..1962472) Escherichia coli ATCC 8739 6064523 YP_001724739.1 CDS EcolC_1762 NC_010468.1 1962469 1963212 R TIGRFAM: methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdy:SDY_1169 hypothetical protein; methyltransferase complement(1962469..1963212) Escherichia coli ATCC 8739 6065581 YP_001724740.1 CDS EcolC_1763 NC_010468.1 1963253 1963648 R KEGG: sdy:SDY_1168 hypothetical protein; hypothetical protein complement(1963253..1963648) Escherichia coli ATCC 8739 6066768 YP_001724741.1 CDS EcolC_1764 NC_010468.1 1963701 1964519 R PFAM: protein of unknown function DUF72; KEGG: stm:STM1903 putative cytoplasmic protein; hypothetical protein complement(1963701..1964519) Escherichia coli ATCC 8739 6067390 YP_001724742.1 CDS EcolC_1765 NC_010468.1 1964516 1965082 R PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1274 hypothetical protein; hypothetical protein complement(1964516..1965082) Escherichia coli ATCC 8739 6065663 YP_001724743.1 CDS aspS NC_010468.1 1965392 1967164 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1965392..1967164 Escherichia coli ATCC 8739 6067667 YP_001724744.1 CDS ntpA NC_010468.1 1967225 1967734 D converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1967225..1967734 Escherichia coli ATCC 8739 6066335 YP_001724745.1 CDS EcolC_1768 NC_010468.1 1967763 1968503 D PFAM: protein of unknown function DUF28; KEGG: ssn:SSON_1277 hypothetical protein; hypothetical protein 1967763..1968503 Escherichia coli ATCC 8739 6066988 YP_001724746.1 CDS ruvC NC_010468.1 1968538 1969059 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1968538..1969059 Escherichia coli ATCC 8739 6065418 YP_001724747.1 CDS EcolC_1770 NC_010468.1 1969061 1969663 R PFAM: protein of unknown function DUF1105; KEGG: ssn:SSON_1279 hypothetical protein; hypothetical protein complement(1969061..1969663) Escherichia coli ATCC 8739 6067561 YP_001724748.1 CDS ruvA NC_010468.1 1969938 1970549 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1969938..1970549 Escherichia coli ATCC 8739 6066611 YP_001724749.1 CDS ruvB NC_010468.1 1970558 1971568 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1970558..1971568 Escherichia coli ATCC 8739 6065764 YP_001724750.1 CDS znuB NC_010468.1 1971715 1972500 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein complement(1971715..1972500) Escherichia coli ATCC 8739 6065117 YP_001724751.1 CDS znuC NC_010468.1 1972497 1973252 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase complement(1972497..1973252) Escherichia coli ATCC 8739 6067077 YP_001724752.1 CDS znuA NC_010468.1 1973331 1974263 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1973331..1974263 Escherichia coli ATCC 8739 6067074 YP_001724753.1 CDS EcolC_1776 NC_010468.1 1974279 1975601 D PFAM: Peptidoglycan-binding LysM; peptidase M23B; Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sbo:SBO_1173 hypothetical protein; hypothetical protein 1974279..1975601 Escherichia coli ATCC 8739 6065745 YP_001724754.1 CDS EcolC_1777 NC_010468.1 1975721 1976692 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1975721..1976692 Escherichia coli ATCC 8739 6067163 YP_001724755.1 CDS EcolC_1778 NC_010468.1 1976823 1978265 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1976823..1978265) Escherichia coli ATCC 8739 6066850 YP_001724756.1 CDS EcolC_1779 NC_010468.1 1978393 1979262 R Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR complement(1978393..1979262) Escherichia coli ATCC 8739 6064936 YP_001724757.1 CDS EcolC_1780 NC_010468.1 1979600 1981075 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1979600..1981075 Escherichia coli ATCC 8739 6067322 YP_001724758.1 CDS EcolC_1781 NC_010468.1 1981310 1983121 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1981310..1983121 Escherichia coli ATCC 8739 6066403 YP_001724759.1 CDS EcolC_1782 NC_010468.1 1983158 1983799 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1983158..1983799 Escherichia coli ATCC 8739 6065731 YP_001724760.1 CDS purT NC_010468.1 1983855 1985033 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(1983855..1985033) Escherichia coli ATCC 8739 6064921 YP_001724761.1 CDS EcolC_1784 NC_010468.1 1985167 1985457 D PFAM: YebG family protein; KEGG: sdy:SDY_1134 hypothetical protein; DNA damage-inducible protein YebG 1985167..1985457 Escherichia coli ATCC 8739 6065548 YP_001724762.1 CDS EcolC_1785 NC_010468.1 1985524 1985880 D secreted protein; unknown function; hypothetical protein 1985524..1985880 Escherichia coli ATCC 8739 6066917 YP_001724763.1 CDS EcolC_1786 NC_010468.1 1986207 1986866 D PFAM: protein of unknown function DUF533; KEGG: sdy:SDY_1132 hypothetical protein; hypothetical protein 1986207..1986866 Escherichia coli ATCC 8739 6066716 YP_001724764.1 CDS EcolC_1787 NC_010468.1 1987075 1989135 D PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1987075..1989135 Escherichia coli ATCC 8739 6066560 YP_001724765.1 CDS EcolC_1788 NC_010468.1 1989132 1989794 R 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X complement(1989132..1989794) Escherichia coli ATCC 8739 6065309 YP_001724766.1 CDS EcolC_1789 NC_010468.1 1989818 1990474 R PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ssn:SSON_1305 hypothetical protein; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase complement(1989818..1990474) Escherichia coli ATCC 8739 6065759 YP_001724767.1 CDS EcolC_1790 NC_010468.1 1990576 1990806 R PFAM: DNA polymerase II beta subunit; KEGG: sdy:SDY_1128 DNA polymerase III, theta subunit; DNA polymerase III subunit theta complement(1990576..1990806) Escherichia coli ATCC 8739 6064675 YP_001724768.1 CDS EcolC_1791 NC_010468.1 1990945 1991319 D PFAM: copper resistance protein CopC; KEGG: sbo:SBO_1145 hypothetical protein; hypothetical protein 1990945..1991319 Escherichia coli ATCC 8739 6066141 YP_001724769.1 CDS EcolC_1792 NC_010468.1 1991323 1992195 D PFAM: copper resistance D domain protein; KEGG: ssn:SSON_1308 putative resistance protein; copper resistance D domain-containing protein 1991323..1992195 Escherichia coli ATCC 8739 6066319 YP_001724770.1 CDS EcolC_1793 NC_010468.1 1992211 1992549 D KEGG: sdy:SDY_1125 hypothetical protein; hypothetical protein 1992211..1992549 Escherichia coli ATCC 8739 6068745 YP_001724771.1 CDS pphA NC_010468.1 1992945 1993601 D Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1992945..1993601 Escherichia coli ATCC 8739 6064762 YP_001724772.1 CDS EcolC_1795 NC_010468.1 1993602 1993877 R PFAM: protein of unknown function DUF1482; KEGG: sdy:SDY_1988 hypothetical protein; hypothetical protein complement(1993602..1993877) Escherichia coli ATCC 8739 6065210 YP_001724773.1 CDS EcolC_1796 NC_010468.1 1993898 1994134 R PFAM: protein of unknown function DUF1480; KEGG: sdy:SDY_1987 hypothetical protein; hypothetical protein complement(1993898..1994134) Escherichia coli ATCC 8739 6065925 YP_001724774.1 CDS yebU NC_010468.1 1994252 1995697 R in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF complement(1994252..1995697) Escherichia coli ATCC 8739 6066012 YP_001724775.1 CDS EcolC_1798 NC_010468.1 1995771 1998404 R PFAM: Mammalian cell entry related domain protein; KEGG: ssn:SSON_1327 hypothetical protein; hypothetical protein complement(1995771..1998404) Escherichia coli ATCC 8739 6065174 YP_001724776.1 CDS EcolC_1799 NC_010468.1 1998373 1999656 R TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: ssn:SSON_1328 hypothetical protein; PqiA family integral membrane protein complement(1998373..1999656) Escherichia coli ATCC 8739 6065646 YP_001724777.1 CDS EcolC_1800 NC_010468.1 1999786 2000283 D PFAM: GAF domain protein; KEGG: sdy:SDY_1980 hypothetical protein; putative GAF sensor protein 1999786..2000283 Escherichia coli ATCC 8739 6066671 YP_001724778.1 CDS EcolC_1801 NC_010468.1 2000380 2001078 D affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 2000380..2001078 Escherichia coli ATCC 8739 6064725 YP_001724779.1 CDS EcolC_1802 NC_010468.1 2001098 2003146 D Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2001098..2003146 Escherichia coli ATCC 8739 6064474 YP_001724780.1 CDS EcolC_1803 NC_010468.1 2003338 2004219 D putative metalloprotease; heat shock protein HtpX 2003338..2004219 Escherichia coli ATCC 8739 6065721 YP_001724781.1 CDS EcolC_1804 NC_010468.1 2004265 2005638 R PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1241 putative transport protein; major facilitator transporter complement(2004265..2005638) Escherichia coli ATCC 8739 6065836 YP_001724782.1 CDS EcolC_1805 NC_010468.1 2005815 2006606 D PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: sbo:SBO_1240 putative regulator; IclR family transcriptional regulator 2005815..2006606 Escherichia coli ATCC 8739 6065812 YP_001724783.1 CDS EcolC_1806 NC_010468.1 2006749 2006988 R KEGG: sdy:SDY_1974 hypothetical protein; hypothetical protein complement(2006749..2006988) Escherichia coli ATCC 8739 6067213 YP_001724784.1 CDS EcolC_1807 NC_010468.1 2007147 2007290 D KEGG: sdy:SDY_1973 hypothetical protein; hypothetical protein 2007147..2007290 Escherichia coli ATCC 8739 6066551 YP_001724785.1 CDS EcolC_1808 NC_010468.1 2007365 2007652 D KEGG: sbo:SBO_1238 hypothetical protein; hypothetical protein 2007365..2007652 Escherichia coli ATCC 8739 6067493 YP_001724786.1 CDS EcolC_1809 NC_010468.1 2008435 2008722 R KEGG: cko:CKO_01153 hypothetical protein; hypothetical protein complement(2008435..2008722) Escherichia coli ATCC 8739 6066552 YP_001724787.1 CDS rrmA NC_010468.1 2008852 2009661 D methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 2008852..2009661 Escherichia coli ATCC 8739 6066454 YP_001724788.1 CDS EcolC_1811 NC_010468.1 2009658 2010224 R membrane protein YebN; hypothetical protein complement(2009658..2010224) Escherichia coli ATCC 8739 6066414 YP_001724789.1 CDS EcolC_1812 NC_010468.1 2010653 2011111 R PFAM: protein of unknown function DUF986; KEGG: sdy:SDY_1966 hypothetical protein; hypothetical protein complement(2010653..2011111) Escherichia coli ATCC 8739 6066288 YP_001724790.1 CDS EcolC_1813 NC_010468.1 2011166 2012017 R hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID complement(2011166..2012017) Escherichia coli ATCC 8739 6066112 YP_001724791.1 CDS EcolC_1814 NC_010468.1 2012030 2012830 R TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sbo:SBO_1230 PTS enzyme IIC, mannose-specific; PTS system mannose/fructose/sorbose family transporter subunit IIC subunit complement(2012030..2012830) Escherichia coli ATCC 8739 6066144 YP_001724792.1 CDS EcolC_1816 NC_010468.1 2013171 2013868 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(2013171..2013614,2013614..2013868)) Escherichia coli ATCC 8739 6066566 YP_001724793.1 CDS EcolC_1817 NC_010468.1 2015104 2016660 D PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: sbo:SBO_1228 putative transport protein; integral membrane protein TerC 2015104..2016660 Escherichia coli ATCC 8739 6064727 YP_001724794.1 CDS EcolC_1818 NC_010468.1 2016664 2018262 R PFAM: EAL domain protein; KEGG: ssn:SSON_1345 hypothetical protein; diguanylate phosphodiesterase complement(2016664..2018262) Escherichia coli ATCC 8739 6065043 YP_001724795.1 CDS EcolC_1819 NC_010468.1 2018393 2019757 R KEGG: sbo:SBO_1270 L-serine deaminase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; L-serine dehydratase 1 complement(2018393..2019757) Escherichia coli ATCC 8739 6064759 YP_001724796.1 CDS EcolC_1820 NC_010468.1 2019941 2020519 R PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1719 hypothetical protein; hypothetical protein complement(2019941..2020519) Escherichia coli ATCC 8739 6065776 YP_001724797.1 CDS EcolC_1821 NC_010468.1 2020523 2021884 R TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: ssn:SSON_1348 p-aminobenzoate synthetase, component I; para-aminobenzoate synthase subunit I complement(2020523..2021884) Escherichia coli ATCC 8739 6065498 YP_001724798.1 CDS EcolC_1822 NC_010468.1 2021958 2022137 D PFAM: protein of unknown function UPF0181; KEGG: sdy:SDY_1717 hypothetical protein; hypothetical protein 2021958..2022137 Escherichia coli ATCC 8739 6066888 YP_001724799.1 CDS EcolC_1823 NC_010468.1 2022257 2022556 R PFAM: Domain of unknown function DUF1889; KEGG: sbo:SBO_1276 hypothetical protein; hypothetical protein complement(2022257..2022556) Escherichia coli ATCC 8739 6066570 YP_001724800.1 CDS EcolC_1824 NC_010468.1 2022978 2023325 R PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_1713 hypothetical protein; endoribonuclease L-PSP complement(2022978..2023325) Escherichia coli ATCC 8739 6066131 YP_001724801.1 CDS EcolC_1825 NC_010468.1 2023454 2025364 D SMART: helicase c2; DEAD-like helicases; KEGG: sbo:SBO_1280 putative enzyme; helicase c2 2023454..2025364 Escherichia coli ATCC 8739 6065726 YP_001724802.1 CDS EcolC_1826 NC_010468.1 2025422 2026117 D PFAM: peptidase M22 glycoprotease; KEGG: sfv:SFV_1422 hypothetical protein; peptidase M22 glycoprotease 2025422..2026117 Escherichia coli ATCC 8739 6065299 YP_001724803.1 CDS EcolC_1827 NC_010468.1 2026157 2026738 D TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sfv:SFV_1423 putative outer membrane protein; Slp family outer membrane lipoprotein 2026157..2026738 Escherichia coli ATCC 8739 6066770 YP_001724804.1 CDS EcolC_1828 NC_010468.1 2026877 2028628 D Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2026877..2028628 Escherichia coli ATCC 8739 6065267 YP_001724805.1 CDS EcolC_1829 NC_010468.1 2028710 2029825 D TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: sfv:SFV_1425 RNase D, processes tRNA precursor; ribonuclease D 2028710..2029825 Escherichia coli ATCC 8739 6064477 YP_001724806.1 CDS EcolC_1830 NC_010468.1 2029878 2030843 R PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ssn:SSON_1358 putative diogenase beta subunit; ferredoxin complement(2029878..2030843) Escherichia coli ATCC 8739 6065712 YP_001724807.1 CDS EcolC_1831 NC_010468.1 2030899 2032023 R PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_1359 hypothetical protein; Rieske (2Fe-2S) domain-containing protein complement(2030899..2032023) Escherichia coli ATCC 8739 6067413 YP_001724808.1 CDS EcolC_1832 NC_010468.1 2032055 2033500 R member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; putative transporter complement(2032055..2033500) Escherichia coli ATCC 8739 6065852 YP_001724809.1 CDS EcolC_1833 NC_010468.1 2033691 2034776 R KEGG: ssn:SSON_1361 putative tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; tartrate dehydrogenase complement(2033691..2034776) Escherichia coli ATCC 8739 6064885 YP_001724810.1 CDS EcolC_1834 NC_010468.1 2034879 2035802 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1289 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2034879..2035802 Escherichia coli ATCC 8739 6065576 YP_001724811.1 CDS EcolC_1835 NC_010468.1 2035929 2036567 D PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sdy:SDY_1698 hypothetical protein; leucine export protein LeuE 2035929..2036567 Escherichia coli ATCC 8739 6064927 YP_001724812.1 CDS EcolC_1836 NC_010468.1 2036740 2037099 D PFAM: Protein of unknown function DUF1971; KEGG: sdy:SDY_1697 hypothetical protein; hypothetical protein 2036740..2037099 Escherichia coli ATCC 8739 6064604 YP_001724813.1 CDS EcolC_1837 NC_010468.1 2037103 2037285 D PFAM: Domain of unknown function DUF1869; KEGG: sdy:SDY_1696 hypothetical protein; hypothetical protein 2037103..2037285 Escherichia coli ATCC 8739 6065786 YP_001724814.1 CDS EcolC_1838 NC_010468.1 2037433 2037681 D PFAM: Transglycosylase-associated protein; KEGG: sdy:SDY_1695 hypothetical protein; hypothetical protein 2037433..2037681 Escherichia coli ATCC 8739 6066211 YP_001724815.1 CDS EcolC_1839 NC_010468.1 2037948 2038973 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: sdy:SDY_1692 hypothetical protein; GAF sensor-containing diguanylate cyclase complement(2037948..2038973) Escherichia coli ATCC 8739 6066355 YP_001724816.1 CDS EcolC_1840 NC_010468.1 2039156 2039410 D PFAM: protein of unknown function DUF333; KEGG: sfx:S1546 hypothetical protein; hypothetical protein 2039156..2039410 Escherichia coli ATCC 8739 6067117 YP_001724817.1 CDS EcolC_1841 NC_010468.1 2039432 2039779 R PFAM: protein of unknown function DUF488; KEGG: ssn:SSON_1369 hypothetical protein; hypothetical protein complement(2039432..2039779) Escherichia coli ATCC 8739 6065441 YP_001724818.1 CDS EcolC_1842 NC_010468.1 2039834 2041015 R TIGRFAM: cyanate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1302 putative amino acid/amine transport protein; cyanate transporter complement(2039834..2041015) Escherichia coli ATCC 8739 6066494 YP_001724819.1 CDS EcolC_1843 NC_010468.1 2041112 2041933 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_1688 putative AraC-type regulatory protein; AraC family transcriptional regulator 2041112..2041933 Escherichia coli ATCC 8739 6064711 YP_001724820.1 CDS EcolC_1844 NC_010468.1 2041890 2042336 R PFAM: protein of unknown function DUF441; KEGG: sbo:SBO_1304 hypothetical protein; hypothetical protein complement(2041890..2042336) Escherichia coli ATCC 8739 6066503 YP_001724821.1 CDS EcolC_1845 NC_010468.1 2042611 2043114 R PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sbo:SBO_1306 hypothetical protein; YbaK/prolyl-tRNA synthetase associated domain-containing protein complement(2042611..2043114) Escherichia coli ATCC 8739 6064658 YP_001724822.1 CDS EcolC_1846 NC_010468.1 2043157 2044647 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1375 hypothetical protein; diguanylate cyclase complement(2043157..2044647) Escherichia coli ATCC 8739 6065158 YP_001724823.1 CDS EcolC_1847 NC_010468.1 2044828 2046303 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1377 hypothetical protein; diguanylate cyclase complement(2044828..2046303) Escherichia coli ATCC 8739 6067436 YP_001724824.1 CDS EcolC_1848 NC_010468.1 2046450 2047733 R PFAM: protein of unknown function DUF444; KEGG: sbo:SBO_1309 hypothetical protein; hypothetical protein complement(2046450..2047733) Escherichia coli ATCC 8739 6065222 YP_001724825.1 CDS EcolC_1849 NC_010468.1 2047846 2049780 R PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: sbo:SBO_1310 hypothetical protein; putative serine protein kinase PrkA complement(2047846..2049780) Escherichia coli ATCC 8739 6065589 YP_001724826.1 CDS EcolC_1850 NC_010468.1 2050216 2050962 D PFAM: MltA-interacting MipA family protein; KEGG: sdy:SDY_1485 hypothetical protein; MltA-interacting MipA family protein 2050216..2050962 Escherichia coli ATCC 8739 6067669 YP_001724827.1 CDS EcolC_1851 NC_010468.1 2051052 2051906 D PFAM: aldo/keto reductase; KEGG: ssn:SSON_1381 putative an aldehyde reductase; aldo/keto reductase 2051052..2051906 Escherichia coli ATCC 8739 6066300 YP_001724828.1 CDS EcolC_1852 NC_010468.1 2051954 2052838 R PFAM: Aldose 1-epimerase; KEGG: sfv:SFV_1435 hypothetical protein; aldose 1-epimerase complement(2051954..2052838) Escherichia coli ATCC 8739 6065799 YP_001724829.1 CDS EcolC_1853 NC_010468.1 2052922 2053917 R TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: sdy:SDY_1488 glyceraldehyde-3-phosphate dehydrogenase A; glyceraldehyde-3-phosphate dehydrogenase complement(2052922..2053917) Escherichia coli ATCC 8739 6065095 YP_001724830.1 CDS EcolC_1854 NC_010468.1 2054259 2054672 D this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2054259..2054672 Escherichia coli ATCC 8739 6065671 YP_001724831.1 CDS EcolC_1855 NC_010468.1 2054714 2054986 D PFAM: protein of unknown function DUF1315; KEGG: sbo:SBO_1318 hypothetical protein; hypothetical protein 2054714..2054986 Escherichia coli ATCC 8739 6066362 YP_001724832.1 CDS EcolC_1856 NC_010468.1 2055356 2056432 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_1491 putative oxidoreductase; alcohol dehydrogenase 2055356..2056432 Escherichia coli ATCC 8739 6066490 YP_001724833.1 CDS EcolC_1857 NC_010468.1 2056459 2057838 D PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_1492 putative transport protein; major facilitator transporter 2056459..2057838 Escherichia coli ATCC 8739 6065264 YP_001724834.1 CDS EcolC_1858 NC_010468.1 2057855 2058898 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sec:SC1309 hypothetical zinc-type alcohol dehydrogenase-like; alcohol dehydrogenase 2057855..2058898 Escherichia coli ATCC 8739 6065152 YP_001724835.1 CDS EcolC_1859 NC_010468.1 2058919 2059755 D KEGG: sfx:S1565 putative aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; ketose-bisphosphate aldolase 2058919..2059755 Escherichia coli ATCC 8739 6065905 YP_001724836.1 CDS EcolC_1860 NC_010468.1 2059760 2060707 D PFAM: PfkB domain protein; KEGG: sfx:S1566 putative kinase; ribokinase-like domain-containing protein 2059760..2060707 Escherichia coli ATCC 8739 6066926 YP_001724837.1 CDS EcolC_1862 NC_010468.1 2061835 2062593 D PFAM: regulatory protein DeoR; KEGG: sdy:SDY_1498 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 2061835..2062593 Escherichia coli ATCC 8739 6066746 YP_001724838.1 CDS EcolC_1863 NC_010468.1 2062711 2064069 D PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sfx:S1569 putative transport protein; major facilitator transporter 2062711..2064069 Escherichia coli ATCC 8739 6066677 YP_001724839.1 CDS EcolC_1864 NC_010468.1 2064162 2064803 R catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase complement(2064162..2064803) Escherichia coli ATCC 8739 6067501 YP_001724840.1 CDS ansA NC_010468.1 2064814 2065830 R converts asparagine to aspartate and ammonia; asparaginase complement(2064814..2065830) Escherichia coli ATCC 8739 6064843 YP_001724841.1 CDS EcolC_1866 NC_010468.1 2065997 2067853 R SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 complement(2065997..2067853) Escherichia coli ATCC 8739 6066463 YP_001724842.1 CDS EcolC_1867 NC_010468.1 2068014 2068565 D PFAM: nitroreductase; KEGG: sbo:SBO_1322 hypothetical protein; hypothetical protein 2068014..2068565 Escherichia coli ATCC 8739 6065245 YP_001724843.1 CDS EcolC_1868 NC_010468.1 2068682 2069725 D catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2068682..2069725 Escherichia coli ATCC 8739 6064451 YP_001724844.1 CDS EcolC_1869 NC_010468.1 2069730 2071691 D decatenates replicating daughter chromosomes; DNA topoisomerase III 2069730..2071691 Escherichia coli ATCC 8739 6064430 YP_001724845.1 CDS EcolC_1870 NC_010468.1 2071819 2072859 D KEGG: sfl:SF1461 hypothetical protein; hypothetical protein 2071819..2072859 Escherichia coli ATCC 8739 6064419 YP_001724846.1 CDS EcolC_1871 NC_010468.1 2072976 2074319 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(2072976..2074319) Escherichia coli ATCC 8739 6064390 YP_001724847.1 CDS EcolC_1872 NC_010468.1 2074555 2074827 D PFAM: protein of unknown function DUF1496; KEGG: sbo:SBO_1329 hypothetical protein; hypothetical protein 2074555..2074827 Escherichia coli ATCC 8739 6064379 YP_001724848.1 CDS EcolC_1873 NC_010468.1 2074793 2075200 R PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1516 hypothetical protein; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase complement(2074793..2075200) Escherichia coli ATCC 8739 6064370 YP_001724849.1 CDS EcolC_1874 NC_010468.1 2075287 2075907 D PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfx:S1582 putative cytochrome oxidase; CDP-alcohol phosphatidyltransferase 2075287..2075907 Escherichia coli ATCC 8739 6064365 YP_001724850.1 CDS EcolC_1875 NC_010468.1 2075916 2077223 R SMART: Rhodanese domain protein; KEGG: sbo:SBO_1332 putative thiosulfate sulfur transferase; rhodanese domain-containing protein complement(2075916..2077223) Escherichia coli ATCC 8739 6064353 YP_001724851.1 CDS EcolC_1876 NC_010468.1 2077290 2077943 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_1462 putative ATP-binding component of a transport system; ABC transporter-like protein complement(2077290..2077943) Escherichia coli ATCC 8739 6064347 YP_001724852.1 CDS EcolC_1877 NC_010468.1 2077943 2079478 R KEGG: sdy:SDY_1520 putative transport system permease protein; putative transport system permease complement(2077943..2079478) Escherichia coli ATCC 8739 6068094 YP_001724853.1 CDS EcolC_1878 NC_010468.1 2079451 2080617 R PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1403 hypothetical protein; putative ABC transporter solute-binding protein complement(2079451..2080617) Escherichia coli ATCC 8739 6067632 YP_001724854.1 CDS EcolC_1879 NC_010468.1 2080627 2081175 R PFAM: Carboxymuconolactone decarboxylase; KEGG: sbo:SBO_1336 hypothetical protein; carboxymuconolactone decarboxylase complement(2080627..2081175) Escherichia coli ATCC 8739 6067353 YP_001724855.1 CDS EcolC_1880 NC_010468.1 2081175 2081882 R PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_1468 hypothetical protein; hypothetical protein complement(2081175..2081882) Escherichia coli ATCC 8739 6066927 YP_001724856.1 CDS EcolC_1881 NC_010468.1 2081897 2082574 R KEGG: ssn:SSON_1406 hypothetical protein; hypothetical protein complement(2081897..2082574) Escherichia coli ATCC 8739 6068736 YP_001724857.1 CDS EcolC_1882 NC_010468.1 2082579 2083289 R PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_1407 hypothetical protein; hypothetical protein complement(2082579..2083289) Escherichia coli ATCC 8739 6065204 YP_001724858.1 CDS EcolC_1883 NC_010468.1 2083456 2084274 R removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III complement(2083456..2084274) Escherichia coli ATCC 8739 6065201 YP_001724859.1 CDS EcolC_1884 NC_010468.1 2084708 2085928 D catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 2084708..2085928 Escherichia coli ATCC 8739 6065166 YP_001724860.1 CDS EcolC_1885 NC_010468.1 2085925 2086959 D KEGG: sdy:SDY_1530 hypothetical protein; TIGRFAM: arginine/ornithine succinyltransferase subunit; arginine N-succinyltransferase; PFAM: arginine N-succinyltransferase beta subunit; arginine succinyltransferase 2085925..2086959 Escherichia coli ATCC 8739 6065150 YP_001724861.1 CDS astD NC_010468.1 2086956 2088434 D a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2086956..2088434 Escherichia coli ATCC 8739 6065099 YP_001724862.1 CDS EcolC_1887 NC_010468.1 2088431 2089774 D catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 2088431..2089774 Escherichia coli ATCC 8739 6065089 YP_001724863.1 CDS EcolC_1888 NC_010468.1 2089767 2090735 D catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 2089767..2090735 Escherichia coli ATCC 8739 6065027 YP_001724864.1 CDS EcolC_1889 NC_010468.1 2091065 2091550 D periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 2091065..2091550 Escherichia coli ATCC 8739 6065021 YP_001724865.1 CDS EcolC_1890 NC_010468.1 2091753 2092328 D PFAM: protein of unknown function DUF886; KEGG: sbo:SBO_1348 hypothetical protein; hypothetical protein 2091753..2092328 Escherichia coli ATCC 8739 6065015 YP_001724866.1 CDS EcolC_1891 NC_010468.1 2092288 2093175 R 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease complement(2092288..2093175) Escherichia coli ATCC 8739 6064956 YP_001724867.1 CDS nadE NC_010468.1 2093405 2094232 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(2093405..2094232) Escherichia coli ATCC 8739 6064933 YP_001724868.1 CDS EcolC_1893 NC_010468.1 2094434 2094772 D osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 2094434..2094772 Escherichia coli ATCC 8739 6064834 YP_001724869.1 CDS EcolC_1894 NC_010468.1 2095071 2095391 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2095071..2095391 Escherichia coli ATCC 8739 6064778 YP_001724870.1 CDS EcolC_1895 NC_010468.1 2095476 2096834 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2095476..2096834 Escherichia coli ATCC 8739 6064733 YP_001724871.1 CDS EcolC_1896 NC_010468.1 2096885 2097235 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2096885..2097235 Escherichia coli ATCC 8739 6064713 YP_001724872.1 CDS EcolC_1897 NC_010468.1 2097246 2098085 D represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 2097246..2098085 Escherichia coli ATCC 8739 6064703 YP_001724873.1 CDS EcolC_1898 NC_010468.1 2098189 2099541 D PFAM: glycoside hydrolase family 4; KEGG: sfx:S1611 cryptic phospho-beta-glucosidase; cryptic; glycoside hydrolase family protein 2098189..2099541 Escherichia coli ATCC 8739 6064701 YP_001724874.1 CDS EcolC_1899 NC_010468.1 2099554 2100303 D PFAM: YdjC family protein; KEGG: ssn:SSON_1425 hypothetical protein; hypothetical protein 2099554..2100303 Escherichia coli ATCC 8739 6064628 YP_001724875.1 CDS katE NC_010468.1 2100561 2102822 R Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II complement(2100561..2102822) Escherichia coli ATCC 8739 6064602 YP_001724876.1 CDS EcolC_1901 NC_010468.1 2103005 2103268 D KEGG: ssn:SSON_1427 hypothetical protein; cell division modulator 2103005..2103268 Escherichia coli ATCC 8739 6064597 YP_001724877.1 CDS EcolC_1902 NC_010468.1 2103557 2104339 D KEGG: sfl:SF1498 hypothetical protein; hypothetical protein 2103557..2104339 Escherichia coli ATCC 8739 6064588 YP_001724878.1 CDS EcolC_1903 NC_010468.1 2104364 2105755 R PFAM: sodium:dicarboxylate symporter; KEGG: sbo:SBO_1361 kinase fragment; sodium:dicarboxylate symporter complement(2104364..2105755) Escherichia coli ATCC 8739 6064583 YP_001724879.1 CDS EcolC_1904 NC_010468.1 2105888 2106478 R PFAM: membrane-bound metal-dependent hydrolase; KEGG: sdy:SDY_1821 hypothetical protein; hypothetical protein complement(2105888..2106478) Escherichia coli ATCC 8739 6064572 YP_001724880.1 CDS EcolC_1905 NC_010468.1 2106641 2107309 R YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase complement(2106641..2107309) Escherichia coli ATCC 8739 6064553 YP_001724881.1 CDS EcolC_1906 NC_010468.1 2107456 2107992 D KEGG: sdy:SDY_1819 hypothetical protein; hypothetical protein 2107456..2107992 Escherichia coli ATCC 8739 6064536 YP_001724882.1 CDS EcolC_1907 NC_010468.1 2108033 2108893 R PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: sdy:SDY_1818 hypothetical protein; fructosamine kinase complement(2108033..2108893) Escherichia coli ATCC 8739 6064492 YP_001724883.1 CDS EcolC_1908 NC_010468.1 2108999 2109289 R KEGG: sdy:SDY_1817 hypothetical protein; hypothetical protein complement(2108999..2109289) Escherichia coli ATCC 8739 6064479 YP_001724884.1 CDS EcolC_1909 NC_010468.1 2109390 2110319 R TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: sbo:SBO_1367 6-phosphofructokinase II; 6-phosphofructokinase complement(2109390..2110319) Escherichia coli ATCC 8739 6064467 YP_001724885.1 CDS EcolC_1910 NC_010468.1 2110606 2111364 D PFAM: protein of unknown function DUF481; KEGG: ssn:SSON_1435 hypothetical protein; hypothetical protein 2110606..2111364 Escherichia coli ATCC 8739 6067631 YP_001724886.1 CDS EcolC_1913 NC_010468.1 2114119 2116047 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 2114119..2116047 Escherichia coli ATCC 8739 6066916 YP_001724887.1 CDS infC NC_010468.1 2116051 2116593 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2116051..2116593 Escherichia coli ATCC 8739 6066921 YP_001724888.1 CDS rpmI NC_010468.1 2116690 2116887 D PFAM: ribosomal protein L35; KEGG: kpn:KPN_02178 50S ribosomal protein L35; 50S ribosomal protein L35 2116690..2116887 Escherichia coli ATCC 8739 6068730 YP_001724889.1 CDS rplT NC_010468.1 2116940 2117296 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2116940..2117296 Escherichia coli ATCC 8739 6068726 YP_001724890.1 CDS pheS NC_010468.1 2117747 2118730 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2117747..2118730 Escherichia coli ATCC 8739 6068722 YP_001724891.1 CDS pheT NC_010468.1 2118745 2121132 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2118745..2121132 Escherichia coli ATCC 8739 6068711 YP_001724892.1 CDS ihfA NC_010468.1 2121137 2121436 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 2121137..2121436 Escherichia coli ATCC 8739 6068707 YP_001724893.1 CDS EcolC_1920 NC_010468.1 2121537 2122517 D with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 2121537..2122517 Escherichia coli ATCC 8739 6068697 YP_001724894.1 CDS btuE NC_010468.1 2122580 2123131 D similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase 2122580..2123131 Escherichia coli ATCC 8739 6068691 YP_001724895.1 CDS EcolC_1922 NC_010468.1 2123131 2123880 D ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 2123131..2123880 Escherichia coli ATCC 8739 6068687 YP_001724896.1 CDS EcolC_1923 NC_010468.1 2123958 2124422 D PFAM: NLP/P60 protein; KEGG: ssn:SSON_1450 lipoprotein; NLP/P60 protein 2123958..2124422 Escherichia coli ATCC 8739 6068683 YP_001724897.1 CDS EcolC_1924 NC_010468.1 2124669 2125382 D KEGG: sbo:SBO_1421 hypothetical protein; putative diguanylate phosphodiesterase 2124669..2125382 Escherichia coli ATCC 8739 6068679 YP_001724898.1 CDS EcolC_1925 NC_010468.1 2125445 2126881 D PFAM: protein of unknown function UPF0061; KEGG: sbo:SBO_1422 hypothetical protein; hypothetical protein 2125445..2126881 Escherichia coli ATCC 8739 6068667 YP_001724899.1 CDS EcolC_1926 NC_010468.1 2126885 2127076 R KEGG: sbo:SBO_1423 hypothetical protein; hypothetical protein complement(2126885..2127076) Escherichia coli ATCC 8739 6068664 YP_001724900.1 CDS EcolC_1927 NC_010468.1 2127208 2128254 R tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2127208..2128254) Escherichia coli ATCC 8739 6068660 YP_001724901.1 CDS EcolC_1928 NC_010468.1 2128411 2129244 R PFAM: protein of unknown function DUF299; KEGG: sdy:SDY_1797 hypothetical protein; hypothetical protein complement(2128411..2129244) Escherichia coli ATCC 8739 6068648 YP_001724902.1 CDS EcolC_1929 NC_010468.1 2129577 2131955 D catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 2129577..2131955 Escherichia coli ATCC 8739 6068640 YP_001724903.1 CDS EcolC_1930 NC_010468.1 2132012 2133658 R acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase complement(2132012..2133658) Escherichia coli ATCC 8739 6068623 YP_001724904.1 CDS EcolC_1931 NC_010468.1 2133715 2134008 R KEGG: sbo:SBO_1431 hypothetical protein; hypothetical protein complement(2133715..2134008) Escherichia coli ATCC 8739 6068612 YP_001724905.1 CDS EcolC_1932 NC_010468.1 2134005 2135294 R PFAM: monooxygenase FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; KEGG: sfv:SFV_1525 probable electron transfer flavoprotein-quinone oxidoreductase YdiS; hypothetical protein complement(2134005..2135294) Escherichia coli ATCC 8739 6068607 YP_001724906.1 CDS EcolC_1933 NC_010468.1 2135350 2136288 R May play a role in a redox process; electron transfer flavoprotein subunit YdiR complement(2135350..2136288) Escherichia coli ATCC 8739 6068590 YP_001724907.1 CDS EcolC_1934 NC_010468.1 2136308 2137072 R YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ complement(2136308..2137072) Escherichia coli ATCC 8739 6068581 YP_001724908.1 CDS EcolC_1935 NC_010468.1 2137388 2138299 D PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; Cupin 2 conserved barrel domain protein; KEGG: sbo:SBO_1435 putative AraC-type regulatory protein; AraC family transcriptional regulator 2137388..2138299 Escherichia coli ATCC 8739 6068575 YP_001724909.1 CDS EcolC_1936 NC_010468.1 2138342 2139493 R may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase complement(2138342..2139493) Escherichia coli ATCC 8739 6068573 YP_001724910.1 CDS EcolC_1937 NC_010468.1 2139507 2141102 R PFAM: coenzyme A transferase; KEGG: stm:STM1357.S putative acetyl-CoA/acetoacetyl-CoA transferase beta subunit; coenzyme A transferase complement(2139507..2141102) Escherichia coli ATCC 8739 6068569 YP_001724911.1 CDS aroD NC_010468.1 2141247 2142005 R catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase complement(2141247..2142005) Escherichia coli ATCC 8739 6068561 YP_001724912.1 CDS EcolC_1939 NC_010468.1 2142036 2142902 R YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase complement(2142036..2142902) Escherichia coli ATCC 8739 6068553 YP_001724913.1 CDS EcolC_1940 NC_010468.1 2142914 2144179 R PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1463 putative amino acid/amine transport protein; major facilitator transporter complement(2142914..2144179) Escherichia coli ATCC 8739 6068548 YP_001724914.1 CDS EcolC_1941 NC_010468.1 2144406 2145620 R PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S1852 putative transport system permease protein; major facilitator transporter complement(2144406..2145620) Escherichia coli ATCC 8739 6068542 YP_001724915.1 CDS EcolC_1942 NC_010468.1 2145720 2146076 R PFAM: Domain of unknown function DUF1870; KEGG: ssn:SSON_1466 hypothetical protein; hypothetical protein complement(2145720..2146076) Escherichia coli ATCC 8739 6068540 YP_001724916.1 CDS EcolC_1943 NC_010468.1 2146505 2147617 R YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein complement(2146505..2147617) Escherichia coli ATCC 8739 6068531 YP_001724917.1 CDS EcolC_1944 NC_010468.1 2148006 2151062 D PFAM: FAD linked oxidase domain protein; KEGG: ssn:SSON_1469 putative oxidase; FAD linked oxidase domain-containing protein 2148006..2151062 Escherichia coli ATCC 8739 6068527 YP_001724918.1 CDS EcolC_1945 NC_010468.1 2151059 2151469 D PFAM: thioesterase superfamily protein; KEGG: sbo:SBO_1444 hypothetical protein; hypothetical protein 2151059..2151469 Escherichia coli ATCC 8739 6068521 YP_001724919.1 CDS EcolC_1946 NC_010468.1 2151569 2151757 D KEGG: sbo:SBO_1445 hypothetical protein; hypothetical protein 2151569..2151757 Escherichia coli ATCC 8739 6068503 YP_001724920.1 CDS sufA NC_010468.1 2152305 2152673 D functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 2152305..2152673 Escherichia coli ATCC 8739 6068489 YP_001724921.1 CDS EcolC_1948 NC_010468.1 2152682 2154169 D with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 2152682..2154169 Escherichia coli ATCC 8739 6068473 YP_001724922.1 CDS sufC NC_010468.1 2154179 2154925 D part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 2154179..2154925 Escherichia coli ATCC 8739 6068461 YP_001724923.1 CDS EcolC_1950 NC_010468.1 2154900 2156171 D with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 2154900..2156171 Escherichia coli ATCC 8739 6068456 YP_001724924.1 CDS EcolC_1951 NC_010468.1 2156168 2157388 D catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 2156168..2157388 Escherichia coli ATCC 8739 6068450 YP_001724925.1 CDS EcolC_1952 NC_010468.1 2157401 2157817 D Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 2157401..2157817 Escherichia coli ATCC 8739 6068437 YP_001724926.1 CDS EcolC_1953 NC_010468.1 2157966 2158970 D PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sfv:SFV_1701 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 2157966..2158970 Escherichia coli ATCC 8739 6068429 YP_001724927.1 CDS EcolC_1954 NC_010468.1 2159034 2159270 R PFAM: LPP repeat-containing protein; KEGG: sdy:SDY_1908 murein lipoprotein; LPP repeat-containing protein complement(2159034..2159270) Escherichia coli ATCC 8739 6068422 YP_001724928.1 CDS EcolC_1955 NC_010468.1 2159581 2160993 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(2159581..2160993) Escherichia coli ATCC 8739 6068415 YP_001724929.1 CDS EcolC_1956 NC_010468.1 2161550 2161759 D KEGG: sdy:SDY_1904 hypothetical protein; hypothetical protein 2161550..2161759 Escherichia coli ATCC 8739 6068396 YP_001724930.1 CDS EcolC_1957 NC_010468.1 2162214 2162840 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_1458 putative oxidoreductase, Fe-S subunit; hypothetical protein 2162214..2162840 Escherichia coli ATCC 8739 6068391 YP_001724931.1 CDS EcolC_1958 NC_010468.1 2162861 2164963 D PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: sbo:SBO_1459 hypothetical protein; putative oxidoreductase 2162861..2164963 Escherichia coli ATCC 8739 6068384 YP_001724932.1 CDS EcolC_1959 NC_010468.1 2164976 2165614 D KEGG: sbo:SBO_1460 hypothetical protein; hypothetical protein 2164976..2165614 Escherichia coli ATCC 8739 6068361 YP_001724933.1 CDS EcolC_1960 NC_010468.1 2165678 2166346 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1899 putative oxidoreductase, Fe-S subunit; 4Fe-4S ferredoxin 2165678..2166346 Escherichia coli ATCC 8739 6068339 YP_001724934.1 CDS EcolC_1961 NC_010468.1 2166343 2167128 D PFAM: cytochrome B561; KEGG: sbo:SBO_1462 hypothetical protein; cytochrome B561 2166343..2167128 Escherichia coli ATCC 8739 6068333 YP_001724935.1 CDS EcolC_1962 NC_010468.1 2167180 2167944 D KEGG: ssn:SSON_1487 hypothetical protein; hypothetical protein 2167180..2167944 Escherichia coli ATCC 8739 6068326 YP_001724936.1 CDS EcolC_1963 NC_010468.1 2167956 2169560 R KEGG: sbo:SBO_1464 hypothetical protein; hypothetical protein complement(2167956..2169560) Escherichia coli ATCC 8739 6068321 YP_001724937.1 CDS EcolC_1964 NC_010468.1 2169686 2169991 R PFAM: Putative mono-oxygenase ydhR; KEGG: sbo:SBO_1465 hypothetical protein; hypothetical protein complement(2169686..2169991) Escherichia coli ATCC 8739 6068316 YP_001724938.1 CDS EcolC_1965 NC_010468.1 2170564 2171820 D KEGG: sdy:SDY_1891 possible enzyme; hypothetical protein 2170564..2171820 Escherichia coli ATCC 8739 6068271 YP_001724939.1 CDS EcolC_1966 NC_010468.1 2171861 2173234 R NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein complement(2171861..2173234) Escherichia coli ATCC 8739 6068252 YP_001724940.1 CDS EcolC_1967 NC_010468.1 2173449 2174090 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2173449..2174090 Escherichia coli ATCC 8739 6068242 YP_001724941.1 CDS EcolC_1968 NC_010468.1 2174130 2175278 R catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase complement(2174130..2175278) Escherichia coli ATCC 8739 6068237 YP_001724942.1 CDS EcolC_1969 NC_010468.1 2175569 2176780 R uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC complement(2175569..2176780) Escherichia coli ATCC 8739 6068231 YP_001724943.1 CDS EcolC_1970 NC_010468.1 2176893 2177825 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1472 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 2176893..2177825 Escherichia coli ATCC 8739 6068223 YP_001724944.1 CDS EcolC_1971 NC_010468.1 2177822 2178847 R binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR complement(2177822..2178847) Escherichia coli ATCC 8739 6068221 YP_001724945.1 CDS EcolC_1972 NC_010468.1 2179401 2180570 D PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_1883 putative transport protein; major facilitator transporter 2179401..2180570 Escherichia coli ATCC 8739 6068217 YP_001724946.1 CDS EcolC_1973 NC_010468.1 2180716 2181297 R SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase complement(2180716..2181297) Escherichia coli ATCC 8739 6068213 YP_001724947.1 CDS EcolC_1974 NC_010468.1 2181425 2182240 R PFAM: NLP/P60 protein; KEGG: ssn:SSON_1501 putative lipoprotein; NLP/P60 protein complement(2181425..2182240) Escherichia coli ATCC 8739 6068208 YP_001724948.1 CDS EcolC_1975 NC_010468.1 2182574 2182921 D TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sdy:SDY_1880 hypothetical protein; hypothetical protein 2182574..2182921 Escherichia coli ATCC 8739 6068204 YP_001724949.1 CDS EcolC_1976 NC_010468.1 2182972 2187588 R similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr complement(2182972..2187588) Escherichia coli ATCC 8739 6068201 YP_001724950.1 CDS EcolC_1977 NC_010468.1 2187681 2188328 R Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T complement(2187681..2188328) Escherichia coli ATCC 8739 6068199 YP_001724951.1 CDS EcolC_1978 NC_010468.1 2188431 2188838 R Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I complement(2188431..2188838) Escherichia coli ATCC 8739 6068195 YP_001724952.1 CDS EcolC_1979 NC_010468.1 2188919 2190016 R FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase complement(2188919..2190016) Escherichia coli ATCC 8739 6068191 YP_001724953.1 CDS EcolC_1980 NC_010468.1 2190053 2190652 R PFAM: regulatory protein TetR; KEGG: sbo:SBO_1487 hypothetical protein; TetR family transcriptional regulator complement(2190053..2190652) Escherichia coli ATCC 8739 6068189 YP_001724954.1 CDS EcolC_1981 NC_010468.1 2190755 2190994 D PFAM: protein of unknown function DUF1289; KEGG: sdy:SDY_1873 hypothetical protein; hypothetical protein 2190755..2190994 Escherichia coli ATCC 8739 6068185 YP_001724955.1 CDS EcolC_1982 NC_010468.1 2191043 2191939 D PFAM: aldo/keto reductase; KEGG: ssn:SSON_1509 hypothetical protein; aldo/keto reductase 2191043..2191939 Escherichia coli ATCC 8739 6068183 YP_001724956.1 CDS EcolC_1983 NC_010468.1 2192005 2192541 D SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 2192005..2192541 Escherichia coli ATCC 8739 6068179 YP_001724957.1 CDS EcolC_1984 NC_010468.1 2192542 2194554 R PFAM: Fusaric acid resistance protein conserved region; KEGG: ssn:SSON_1511 hypothetical protein; fusaric acid resistance protein complement(2192542..2194554) Escherichia coli ATCC 8739 6068177 YP_001724958.1 CDS EcolC_1985 NC_010468.1 2194554 2195411 R PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_1663 hypothetical protein; secretion protein HlyD family protein complement(2194554..2195411) Escherichia coli ATCC 8739 6068174 YP_001724959.1 CDS EcolC_1986 NC_010468.1 2195414 2195641 R PFAM: protein of unknown function DUF1656; KEGG: ssn:SSON_1513 hypothetical protein; hypothetical protein complement(2195414..2195641) Escherichia coli ATCC 8739 6068170 YP_001724960.1 CDS EcolC_1987 NC_010468.1 2195845 2196285 D Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 2195845..2196285 Escherichia coli ATCC 8739 6068167 YP_001724961.1 CDS EcolC_1988 NC_010468.1 2196332 2196799 R PFAM: 17 kDa surface antigen; KEGG: sdy:SDY_1864 putative outer membrane protein; 17 kDa surface antigen complement(2196332..2196799) Escherichia coli ATCC 8739 6068165 YP_001724962.1 CDS anmK NC_010468.1 2197073 2198182 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 2197073..2198182 Escherichia coli ATCC 8739 6068163 YP_001724963.1 CDS EcolC_1990 NC_010468.1 2198286 2198609 D MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 2198286..2198609 Escherichia coli ATCC 8739 6068160 YP_001724964.1 CDS EcolC_1991 NC_010468.1 2198668 2199324 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2198668..2199324 Escherichia coli ATCC 8739 6068157 YP_001724965.1 CDS EcolC_1992 NC_010468.1 2199453 2200727 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2199453..2200727 Escherichia coli ATCC 8739 6068155 YP_001724966.1 CDS EcolC_1993 NC_010468.1 2200789 2201649 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 2200789..2201649 Escherichia coli ATCC 8739 6068151 YP_001724967.1 CDS EcolC_1994 NC_010468.1 2201693 2202298 R PFAM: Glutathione S-transferase domain; KEGG: sdy:SDY_1858 glutathionine S-transferase; glutathionine S-transferase complement(2201693..2202298) Escherichia coli ATCC 8739 6068148 YP_001724968.1 CDS tppB NC_010468.1 2202404 2203906 R mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease complement(2202404..2203906) Escherichia coli ATCC 8739 6068146 YP_001724969.1 CDS EcolC_1996 NC_010468.1 2204517 2205152 R DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III complement(2204517..2205152) Escherichia coli ATCC 8739 6068144 YP_001724970.1 CDS EcolC_1997 NC_010468.1 2205152 2205847 R in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE complement(2205152..2205847) Escherichia coli ATCC 8739 6068141 YP_001724971.1 CDS EcolC_1998 NC_010468.1 2205851 2206471 R part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG complement(2205851..2206471) Escherichia coli ATCC 8739 6068138 YP_001724972.1 CDS rnfD NC_010468.1 2206475 2207533 R RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD complement(2206475..2207533) Escherichia coli ATCC 8739 6068135 YP_001724973.1 CDS EcolC_2000 NC_010468.1 2207534 2209756 R part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC complement(2207534..2209756) Escherichia coli ATCC 8739 6068133 YP_001724974.1 CDS EcolC_2001 NC_010468.1 2209749 2210327 R part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB complement(2209749..2210327) Escherichia coli ATCC 8739 6068125 YP_001724975.1 CDS EcolC_2002 NC_010468.1 2210327 2210908 R TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: sdy:SDY_1850 hypothetical protein; Na(+)-translocating NADH-quinone reductase subunit E complement(2210327..2210908) Escherichia coli ATCC 8739 6068122 YP_001724976.1 CDS EcolC_2003 NC_010468.1 2210985 2211425 R KEGG: ssn:SSON_1532 hypothetical protein; hypothetical protein complement(2210985..2211425) Escherichia coli ATCC 8739 6068118 YP_001724977.1 CDS EcolC_2004 NC_010468.1 2211511 2211726 R YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein complement(2211511..2211726) Escherichia coli ATCC 8739 6068113 YP_001724978.1 CDS EcolC_2005 NC_010468.1 2211999 2212124 R KEGG: cko:CKO_01632 hypothetical protein; hypothetical protein complement(2211999..2212124) Escherichia coli ATCC 8739 6068104 YP_001724979.1 CDS EcolC_2006 NC_010468.1 2212367 2213407 D PFAM: Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain protein; Oxidoreductase domain; KEGG: sbo:SBO_1510 hypothetical protein; putative oxidoreductase 2212367..2213407 Escherichia coli ATCC 8739 6068085 YP_001724980.1 CDS EcolC_2007 NC_010468.1 2213441 2214442 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(2213441..2214442) Escherichia coli ATCC 8739 6068080 YP_001724981.1 CDS EcolC_2008 NC_010468.1 2214546 2215718 R PFAM: aminotransferase class I and II; KEGG: sbo:SBO_1512 MalY; class I and II aminotransferase complement(2214546..2215718) Escherichia coli ATCC 8739 6068075 YP_001724982.1 CDS EcolC_2010 NC_010468.1 2217494 2218522 D regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 2217494..2218522 Escherichia coli ATCC 8739 6068064 YP_001724983.1 CDS EcolC_2011 NC_010468.1 2218634 2219401 D Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 2218634..2219401 Escherichia coli ATCC 8739 6068056 YP_001724984.1 CDS EcolC_2012 NC_010468.1 2219622 2220212 D PFAM: regulatory protein TetR; KEGG: sdy:SDY_1837 repressor for uid operon; TetR family transcriptional regulator 2219622..2220212 Escherichia coli ATCC 8739 6068052 YP_001724985.1 CDS EcolC_2013 NC_010468.1 2220603 2222414 D PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: ssn:SSON_1543 beta-D-glucuronidase; beta-D-glucuronidase 2220603..2222414 Escherichia coli ATCC 8739 6068046 YP_001724986.1 CDS EcolC_2015 NC_010468.1 2223822 2225087 D KEGG: ssn:SSON_1545 membrane-associated protein; putative outer membrane porin protein 2223822..2225087 Escherichia coli ATCC 8739 6068033 YP_001724987.1 CDS EcolC_2016 NC_010468.1 2225132 2226640 R PFAM: protein of unknown function DUF945; KEGG: ssn:SSON_1546 hypothetical protein; hypothetical protein complement(2225132..2226640) Escherichia coli ATCC 8739 6068021 YP_001724988.1 CDS EcolC_2017 NC_010468.1 2226741 2227916 R KEGG: sbo:SBO_1523 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; mannose-6-phosphate isomerase complement(2226741..2227916) Escherichia coli ATCC 8739 6068008 YP_001724989.1 CDS EcolC_2018 NC_010468.1 2228115 2229761 D TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sbo:SBO_1524 fumarase A; tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta 2228115..2229761 Escherichia coli ATCC 8739 6068000 YP_001724990.1 CDS fumC NC_010468.1 2229904 2231307 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 2229904..2231307 Escherichia coli ATCC 8739 6067990 YP_001724991.1 CDS EcolC_2020 NC_010468.1 2231304 2232233 R binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein complement(2231304..2232233) Escherichia coli ATCC 8739 6067979 YP_001724992.1 CDS EcolC_2021 NC_010468.1 2232309 2233610 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_1825 sensor histidine protein kinase; sensor protein RstB complement(2232309..2233610) Escherichia coli ATCC 8739 6067965 YP_001724993.1 CDS EcolC_2022 NC_010468.1 2233614 2234333 R response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA complement(2233614..2234333) Escherichia coli ATCC 8739 6067954 YP_001724994.1 CDS EcolC_2023 NC_010468.1 2234462 2234797 D PFAM: GlpM family protein; KEGG: sdy:SDY_1546 hypothetical protein; GlpM family protein 2234462..2234797 Escherichia coli ATCC 8739 6067950 YP_001724995.1 CDS EcolC_2024 NC_010468.1 2234794 2235516 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_1547 putative oxidoreductase; short chain dehydrogenase complement(2234794..2235516) Escherichia coli ATCC 8739 6067941 YP_001724996.1 CDS EcolC_2025 NC_010468.1 2235553 2236935 R TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: sfv:SFV_1620 putative arginine/ornithine antiporter; arginine/ornithine antiporter complement(2235553..2236935) Escherichia coli ATCC 8739 6067938 YP_001724997.1 CDS EcolC_2026 NC_010468.1 2237121 2238065 R PFAM: protein of unknown function DUF1471; KEGG: sdy:SDY_1549 hypothetical protein; hypothetical protein complement(2237121..2238065) Escherichia coli ATCC 8739 6067921 YP_001724998.1 CDS pntA NC_010468.1 2238589 2240121 D forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 2238589..2240121 Escherichia coli ATCC 8739 6067915 YP_001724999.1 CDS pntB NC_010468.1 2240132 2241520 D catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 2240132..2241520 Escherichia coli ATCC 8739 6067913 YP_001725000.1 CDS tqsA NC_010468.1 2241545 2242579 R transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein complement(2241545..2242579) Escherichia coli ATCC 8739 6067906 YP_001725001.1 CDS EcolC_2030 NC_010468.1 2242991 2243356 D with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 2242991..2243356 Escherichia coli ATCC 8739 6067898 YP_001725002.1 CDS EcolC_2031 NC_010468.1 2243343 2243672 D with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 2243343..2243672 Escherichia coli ATCC 8739 6067886 YP_001725003.1 CDS EcolC_2032 NC_010468.1 2243711 2244532 R PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: sfv:SFV_1613 hypothetical protein; peptidase S1 and S6 chymotrypsin/Hap complement(2243711..2244532) Escherichia coli ATCC 8739 6067881 YP_001725004.1 CDS EcolC_2033 NC_010468.1 2244808 2245116 R required for growth and survival under moderately acid conditions; acid shock protein complement(2244808..2245116) Escherichia coli ATCC 8739 6067873 YP_001725005.1 CDS EcolC_2034 NC_010468.1 2245540 2246793 R PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1568 putative transport protein; major facilitator transporter complement(2245540..2246793) Escherichia coli ATCC 8739 6067867 YP_001725006.1 CDS EcolC_2035 NC_010468.1 2246900 2247793 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1569 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2246900..2247793 Escherichia coli ATCC 8739 6067854 YP_001725007.1 CDS EcolC_2036 NC_010468.1 2247928 2249148 D PFAM: ROK family protein; KEGG: ssn:SSON_1570 putative NAGC-like transcriptional regulator; ROK family protein 2247928..2249148 Escherichia coli ATCC 8739 6067852 YP_001725008.1 CDS EcolC_2037 NC_010468.1 2249273 2249968 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase 2249273..2249968 Escherichia coli ATCC 8739 6067850 YP_001725009.1 CDS EcolC_2038 NC_010468.1 2249921 2251177 R PFAM: Chloride channel core; KEGG: sbo:SBO_1544 putative chloride channel; putative voltage-gated ClC-type chloride channel ClcB complement(2249921..2251177) Escherichia coli ATCC 8739 6067848 YP_001725010.1 CDS EcolC_2039 NC_010468.1 2251372 2251986 R binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD complement(2251372..2251986) Escherichia coli ATCC 8739 6067841 YP_001725011.1 CDS EcolC_2040 NC_010468.1 2252029 2252883 R PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_1546 putative DMSO reductase anchor subunit; DMSO reductase anchor subunit DmsC complement(2252029..2252883) Escherichia coli ATCC 8739 6067833 YP_001725012.1 CDS EcolC_2041 NC_010468.1 2252885 2253502 R TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1567 putative oxidoreductase, Fe-S subunit; dimethylsulfoxide reductase subunit B complement(2252885..2253502) Escherichia coli ATCC 8739 6067830 YP_001725013.1 CDS EcolC_2042 NC_010468.1 2253513 2255936 R TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sbo:SBO_1548 putative oxidoreductase, major subunit; anaerobic dimethyl sulfoxide reductase subunit A complement(2253513..2255936) Escherichia coli ATCC 8739 6067817 YP_001725014.1 CDS EcolC_2043 NC_010468.1 2255997 2258423 R TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: stm:STM1499 putative dimethyl sulphoxide reductase, chain A1; anaerobic dimethyl sulfoxide reductase subunit A complement(2255997..2258423) Escherichia coli ATCC 8739 6067808 YP_001725015.1 CDS EcolC_2044 NC_010468.1 2258622 2258927 R PFAM: protein of unknown function DUF1161; KEGG: sfv:SFV_1558 hypothetical protein; hypothetical protein complement(2258622..2258927) Escherichia coli ATCC 8739 6067802 YP_001725016.1 CDS EcolC_2045 NC_010468.1 2258999 2259745 D PFAM: protein of unknown function UPF0257; KEGG: sfv:SFV_1559 hypothetical protein; hypothetical protein 2258999..2259745 Escherichia coli ATCC 8739 6067795 YP_001725017.1 CDS EcolC_2046 NC_010468.1 2259748 2260308 R PFAM: GCN5-related N-acetyltransferase; KEGG: cko:CKO_01578 hypothetical protein; N-acetyltransferase GCN5 complement(2259748..2260308) Escherichia coli ATCC 8739 6067784 YP_001725018.1 CDS EcolC_2047 NC_010468.1 2260343 2260684 R PFAM: protein of unknown function DUF1283; KEGG: sfv:SFV_1561 hypothetical protein; hypothetical protein complement(2260343..2260684) Escherichia coli ATCC 8739 6067777 YP_001725019.1 CDS EcolC_2048 NC_010468.1 2260819 2261145 D PFAM: protein of unknown function UPF0060; KEGG: sdy:SDY_1577 hypothetical protein; hypothetical protein 2260819..2261145 Escherichia coli ATCC 8739 6067767 YP_001725020.1 CDS EcolC_2049 NC_010468.1 2261351 2262565 D PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sfx:S1718 starvation sensing protein; mandelate racemase/muconate lactonizing protein 2261351..2262565 Escherichia coli ATCC 8739 6067763 YP_001725021.1 CDS EcolC_2050 NC_010468.1 2262577 2263596 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cko:CKO_01574 hypothetical protein; putative dehydrogenase 2262577..2263596 Escherichia coli ATCC 8739 6067750 YP_001725022.1 CDS EcolC_2051 NC_010468.1 2263654 2263764 D KEGG: cko:CKO_01573 hypothetical protein; hypothetical protein 2263654..2263764 Escherichia coli ATCC 8739 6067747 YP_001725023.1 CDS EcolC_2052 NC_010468.1 2263784 2265079 R PFAM: integrase family protein; KEGG: stm:STM0893 putative integrase; integrase family protein complement(2263784..2265079) Escherichia coli ATCC 8739 6067742 YP_001725024.1 CDS EcolC_2053 NC_010468.1 2265099 2265350 R PFAM: protein of unknown function DUF1233 excisionase putative; KEGG: esa:ESA_01609 hypothetical protein; hypothetical protein complement(2265099..2265350) Escherichia coli ATCC 8739 6067728 YP_001725025.1 CDS EcolC_2054 NC_010468.1 2265423 2267900 R PFAM: Exonuclease RNase T and DNA polymerase III; KEGG: sbo:SBO_0976 putative exodeoxyribonuclease VIII; exonuclease RNase T and DNA polymerase III complement(2265423..2267900) Escherichia coli ATCC 8739 6067715 YP_001725026.1 CDS EcolC_2055 NC_010468.1 2267993 2268184 R PFAM: protein of unknown function DUF1482; KEGG: cko:CKO_01911 hypothetical protein; hypothetical protein complement(2267993..2268184) Escherichia coli ATCC 8739 6067706 YP_001725027.1 CDS EcolC_2056 NC_010468.1 2268937 2269155 R hypothetical protein complement(2268937..2269155) Escherichia coli ATCC 8739 6067689 YP_001725028.1 CDS EcolC_2057 NC_010468.1 2269315 2269470 R PFAM: protein of unknown function DUF1391; KEGG: ssn:SSON_0728 hypothetical prophage protein; hypothetical protein complement(2269315..2269470) Escherichia coli ATCC 8739 6067683 YP_001725029.1 CDS EcolC_2058 NC_010468.1 2269637 2270044 R The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA complement(2269637..2270044) Escherichia coli ATCC 8739 6067675 YP_001725030.1 CDS EcolC_2059 NC_010468.1 2270128 2270358 D KEGG: sfv:SFV_0741 putative regulator of cell division encoded by prophage; DNA-binding transcriptional regulator DicC 2270128..2270358 Escherichia coli ATCC 8739 6067659 YP_001725031.1 CDS EcolC_2060 NC_010468.1 2270342 2270863 D PFAM: protein of unknown function DUF1019; hypothetical protein 2270342..2270863 Escherichia coli ATCC 8739 6067649 YP_001725032.1 CDS EcolC_2061 NC_010468.1 2270895 2271809 D KEGG: ent:Ent638_2616 hypothetical protein; hypothetical protein 2270895..2271809 Escherichia coli ATCC 8739 6067641 YP_001725033.1 CDS EcolC_2062 NC_010468.1 2271850 2272272 D PFAM: protein of unknown function DUF977; KEGG: sbo:SBO_0970 putative bacteriophage protein; hypothetical protein 2271850..2272272 Escherichia coli ATCC 8739 6067639 YP_001725034.1 CDS EcolC_2063 NC_010468.1 2272269 2272625 D KEGG: ent:Ent638_1018 putative methyltransferase; putative methyltransferase 2272269..2272625 Escherichia coli ATCC 8739 6067622 YP_001725035.1 CDS EcolC_2068 NC_010468.1 2273778 2273957 D KEGG: sbo:SBO_0964 hypothetical protein; hypothetical protein 2273778..2273957 Escherichia coli ATCC 8739 6067571 YP_001725036.1 CDS EcolC_2069 NC_010468.1 2274292 2275605 D PFAM: Integrase catalytic region; KEGG: kpn:KPN_pKPN3p05906 Sea24; integrase catalytic subunit 2274292..2275605 Escherichia coli ATCC 8739 6067550 YP_001725037.1 CDS EcolC_2070 NC_010468.1 2276067 2276399 R KEGG: ent:Ent638_2935 hypothetical protein; hypothetical protein complement(2276067..2276399) Escherichia coli ATCC 8739 6067545 YP_001725038.1 CDS EcolC_2071 NC_010468.1 2276932 2277171 D Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 2276932..2277171 Escherichia coli ATCC 8739 6067541 YP_001725039.1 CDS EcolC_2072 NC_010468.1 2277171 2277458 D TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sfx:S1669 RelE protein; addiction module antitoxin 2277171..2277458 Escherichia coli ATCC 8739 6067524 YP_001725040.1 CDS EcolC_2073 NC_010468.1 2277530 2277685 D PFAM: Hok/gef cell toxic protein; KEGG: sdy:SDY_1432 polypeptide destructive to membrane potential; Hok/gef cell toxic protein 2277530..2277685 Escherichia coli ATCC 8739 6067498 YP_001725041.1 CDS EcolC_2074 NC_010468.1 2277902 2278153 D KEGG: sdy:SDY_1433 hypothetical protein; hypothetical protein 2277902..2278153 Escherichia coli ATCC 8739 6067487 YP_001725042.1 CDS EcolC_2075 NC_010468.1 2278220 2278498 D KEGG: sfl:SF2042 hypothetical protein; hypothetical protein 2278220..2278498 Escherichia coli ATCC 8739 6067478 YP_001725043.1 CDS EcolC_2076 NC_010468.1 2278500 2279549 D PFAM: protein of unknown function DUF1277; SMART: HNH nuclease; KEGG: sfl:SF1546 hypothetical bacteriophage protein; hypothetical protein 2278500..2279549 Escherichia coli ATCC 8739 6067458 YP_001725044.1 CDS EcolC_2077 NC_010468.1 2279563 2280315 D PFAM: antitermination protein; KEGG: esa:ESA_01015 hypothetical protein; antitermination protein 2279563..2280315 Escherichia coli ATCC 8739 6067448 YP_001725045.1 CDS EcolC_2078 NC_010468.1 2280737 2280937 R PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: spt:SPA1603 putative cold shock protein; cold-shock DNA-binding domain-containing protein complement(2280737..2280937) Escherichia coli ATCC 8739 6067427 YP_001725046.1 CDS EcolC_2079 NC_010468.1 2281250 2281465 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ent:Ent638_0166 putative cold-shock DNA-binding domain protein; cold-shock DNA-binding domain-containing protein 2281250..2281465 Escherichia coli ATCC 8739 6067417 YP_001725047.1 CDS EcolC_2080 NC_010468.1 2281714 2281845 D hypothetical protein 2281714..2281845 Escherichia coli ATCC 8739 6067397 YP_001725048.1 CDS EcolC_2081 NC_010468.1 2282219 2282434 D PFAM: Lysis S family protein; KEGG: ssn:SSON_2438 hypothetical protein; lysis S family protein 2282219..2282434 Escherichia coli ATCC 8739 6067394 YP_001725049.1 CDS EcolC_2082 NC_010468.1 2282439 2282750 D PFAM: protein of unknown function DUF1327; KEGG: ssn:SSON_1892 hypothetical bacteriophage protein; hypothetical protein 2282439..2282750 Escherichia coli ATCC 8739 6067392 YP_001725050.1 CDS EcolC_2083 NC_010468.1 2282747 2283280 D PFAM: glycoside hydrolase family 24; KEGG: sfx:S0733 putative endolysin R of prophage CP-933V; lysozyme 2282747..2283280 Escherichia coli ATCC 8739 6067386 YP_001725051.1 CDS EcolC_2084 NC_010468.1 2283292 2283774 D KEGG: stm:STM1869 phage-tail assembly-like protein; phage-tail assembly-like protein 2283292..2283774 Escherichia coli ATCC 8739 6067371 YP_001725052.1 CDS EcolC_2085 NC_010468.1 2284137 2284349 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: stm:STM1996 putative cold-shock protein; cold-shock DNA-binding domain-containing protein 2284137..2284349 Escherichia coli ATCC 8739 6067367 YP_001725053.1 CDS EcolC_2086 NC_010468.1 2284675 2284851 D hypothetical protein 2284675..2284851 Escherichia coli ATCC 8739 6067363 YP_001725054.1 CDS EcolC_2087 NC_010468.1 2285023 2285196 D PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA; GnsAGnsB family protein 2285023..2285196 Escherichia coli ATCC 8739 6067348 YP_001725055.1 CDS EcolC_2088 NC_010468.1 2285348 2285758 R PFAM: protein of unknown function DUF1398; KEGG: ssn:SSON_2432 hypothetical protein; hypothetical protein complement(2285348..2285758) Escherichia coli ATCC 8739 6067340 YP_001725056.1 CDS EcolC_2089 NC_010468.1 2285816 2286049 R hypothetical protein complement(2285816..2286049) Escherichia coli ATCC 8739 6067325 YP_001725057.1 CDS EcolC_2090 NC_010468.1 2286438 2286983 D PFAM: DNA packaging Nu1; KEGG: ssn:SSON_2431 bacteriophage DNA packaging protein; DNA packaging Nu1 2286438..2286983 Escherichia coli ATCC 8739 6067312 YP_001725058.1 CDS EcolC_2091 NC_010468.1 2286958 2288883 D PFAM: terminase GpA; KEGG: ssn:SSON_2430 putative DNA packaging protein of prophage; terminase GpA 2286958..2288883 Escherichia coli ATCC 8739 6067309 YP_001725059.1 CDS EcolC_2092 NC_010468.1 2288880 2289086 D PFAM: Head-to-tail joining protein W gpW family protein; KEGG: ssn:SSON_2429 putative head-tail joining protein of prophage; head-to-tail joining protein W 2288880..2289086 Escherichia coli ATCC 8739 6067305 YP_001725060.1 CDS EcolC_2093 NC_010468.1 2289083 2290684 D TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda; KEGG: ssn:SSON_2428 putative capsid structural protein of prophage; lambda family phage portal protein 2289083..2290684 Escherichia coli ATCC 8739 6067303 YP_001725061.1 CDS EcolC_2094 NC_010468.1 2290665 2291984 D PFAM: peptidase S49; KEGG: ssn:SSON_2427 putative minor capsid protein precursor; peptidase S49 2290665..2291984 Escherichia coli ATCC 8739 6067300 YP_001725062.1 CDS EcolC_2095 NC_010468.1 2291994 2292326 D PFAM: lambda head decoration protein D HDPD; KEGG: ssn:SSON_2426 putative head decoration protein; lambda head decoration protein D HDPD 2291994..2292326 Escherichia coli ATCC 8739 6067287 YP_001725063.1 CDS EcolC_2096 NC_010468.1 2292382 2293407 D PFAM: major capsid protein E; KEGG: ssn:SSON_2425 putative major capsid protein; major capsid protein E 2292382..2293407 Escherichia coli ATCC 8739 6067285 YP_001725064.1 CDS EcolC_2097 NC_010468.1 2293449 2293844 D KEGG: ssn:SSON_2424 putative DNA-packaging protein; putative DNA-packaging protein 2293449..2293844 Escherichia coli ATCC 8739 6067278 YP_001725065.1 CDS EcolC_2098 NC_010468.1 2293856 2294209 D PFAM: head-tail attachment protein; KEGG: ssn:SSON_2423 putative head-tail joining protein of prophage; head-tail attachment protein 2293856..2294209 Escherichia coli ATCC 8739 6067266 YP_001725066.1 CDS EcolC_2099 NC_010468.1 2294297 2294797 D PFAM: Prophage minor tail Z family protein; KEGG: ssn:SSON_2422 putative tail component of prophage; prophage minor tail Z family protein 2294297..2294797 Escherichia coli ATCC 8739 6067257 YP_001725067.1 CDS EcolC_2100 NC_010468.1 2294794 2295189 D PFAM: minor tail U; KEGG: ssn:SSON_2421 putative tail component of prophage; minor tail family protein 2294794..2295189 Escherichia coli ATCC 8739 6067253 YP_001725068.1 CDS EcolC_2101 NC_010468.1 2295197 2295937 D PFAM: Ig domain protein group 2 domain protein; KEGG: ssn:SSON_2420 putative tail component of prophage; Ig domain-containing protein 2295197..2295937 Escherichia coli ATCC 8739 6067247 YP_001725069.1 CDS EcolC_2102 NC_010468.1 2295953 2296375 D TIGRFAM: phage minor tail protein G; PFAM: minor tail protein G; KEGG: ssn:SSON_2419 putative tail component of prophage; phage minor tail protein G 2295953..2296375 Escherichia coli ATCC 8739 6067243 YP_001725070.1 CDS EcolC_2103 NC_010468.1 2296357 2296791 D TIGRFAM: phage tail assembly protein T; PFAM: Minor tail T family protein; KEGG: ssn:SSON_2418 putative tail component of prophage; phage tail assembly protein T 2296357..2296791 Escherichia coli ATCC 8739 6067241 YP_001725071.1 CDS EcolC_2104 NC_010468.1 2296784 2299345 D TIGRFAM: phage tail tape measure protein, lambda family; PFAM: Prophage tail length tape measure; KEGG: ssn:SSON_2417 putative tail length tape measure protein; lambda family phage tail tape measure protein 2296784..2299345 Escherichia coli ATCC 8739 6067235 YP_001725072.1 CDS EcolC_2105 NC_010468.1 2299342 2299671 D PFAM: minor tail family protein; KEGG: ssn:SSON_2416 putative minor tail protein; minor tail family protein 2299342..2299671 Escherichia coli ATCC 8739 6067226 YP_001725073.1 CDS EcolC_2106 NC_010468.1 2299671 2300369 D TIGRFAM: phage minor tail protein L; PFAM: minor tail protein L; KEGG: ssn:SSON_2415 putative minor tail protein; phage minor tail protein L 2299671..2300369 Escherichia coli ATCC 8739 6067224 YP_001725074.1 CDS EcolC_2107 NC_010468.1 2300375 2301118 D PFAM: NLP/P60 protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: ssn:SSON_2414 tail assembly protein; NLP/P60 protein 2300375..2301118 Escherichia coli ATCC 8739 6067219 YP_001725075.1 CDS EcolC_2108 NC_010468.1 2301115 2301687 D PFAM: lambda tail assembly I; KEGG: ssn:SSON_2413 putative tail component of prophage; lambda tail assembly I 2301115..2301687 Escherichia coli ATCC 8739 6067206 YP_001725076.1 CDS EcolC_2109 NC_010468.1 2301748 2305227 D PFAM: Fibronectin type III domain protein; Protein of unknown function DUF1983; KEGG: ssn:SSON_1763 host specificity protein; hypothetical protein 2301748..2305227 Escherichia coli ATCC 8739 6067203 YP_001725077.1 CDS EcolC_2110 NC_010468.1 2305295 2305894 D PFAM: virulence-related outer membrane protein; KEGG: sbo:SBO_1197 putative membrane protein precursor; virulence-related outer membrane protein 2305295..2305894 Escherichia coli ATCC 8739 6067172 YP_001725078.1 CDS EcolC_2111 NC_010468.1 2305959 2308982 D PFAM: tail fiber repeat containing protein; tail fiber repeat 2 protein; Tail Collar domain protein; Prophage tail fibre domain protein; KEGG: ssn:SSON_2410 phage protein-related; prophage tail fiber domain-containing protein 2305959..2308982 Escherichia coli ATCC 8739 6067136 YP_001725079.1 CDS EcolC_2112 NC_010468.1 2308982 2309557 D PFAM: tail assembly chaperone gp38; KEGG: stm:STM1050 tail fiber assembly like-protein; tail assembly chaperone gp38 2308982..2309557 Escherichia coli ATCC 8739 6067134 YP_001725080.1 CDS EcolC_2113 NC_010468.1 2309655 2310245 R PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: sbl:Sbal_4419 resolvase, N-terminal domain; resolvase domain-containing protein complement(2309655..2310245) Escherichia coli ATCC 8739 6067121 YP_001725081.1 CDS EcolC_2114 NC_010468.1 2310562 2310795 R KEGG: ent:Ent638_2496 DNA-binding transcriptional regulator; DNA-binding transcriptional regulator complement(2310562..2310795) Escherichia coli ATCC 8739 6067109 YP_001725082.1 CDS EcolC_2115 NC_010468.1 2311582 2312865 D TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_1582 putative transport protein; major facilitator superfamily metabolite/H(+) symporter 2311582..2312865 Escherichia coli ATCC 8739 6067107 YP_001725083.1 CDS EcolC_2116 NC_010468.1 2312954 2314414 D PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfx:S1678 putative oxidoreductase; mannitol dehydrogenase domain-containing protein 2312954..2314414 Escherichia coli ATCC 8739 6067095 YP_001725084.1 CDS EcolC_2117 NC_010468.1 2314450 2314653 R KEGG: sdy:SDY_1584 hypothetical protein; hypothetical protein complement(2314450..2314653) Escherichia coli ATCC 8739 6067073 YP_001725085.1 CDS EcolC_2118 NC_010468.1 2314830 2315516 R PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ssn:SSON_1588 hypothetical protein; GntR family transcriptional regulator complement(2314830..2315516) Escherichia coli ATCC 8739 6067070 YP_001725086.1 CDS EcolC_2119 NC_010468.1 2315605 2316351 R NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase complement(2315605..2316351) Escherichia coli ATCC 8739 6067049 YP_001725087.1 CDS EcolC_2120 NC_010468.1 2316488 2318533 D PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: ssn:SSON_1590 dipeptidyl carboxypeptidase II; dipeptidyl carboxypeptidase II 2316488..2318533 Escherichia coli ATCC 8739 6066996 YP_001725088.1 CDS EcolC_2121 NC_010468.1 2318578 2319096 R PFAM: CinA domain protein; KEGG: sdy:SDY_1588 hypothetical protein; competence damage-inducible protein A complement(2318578..2319096) Escherichia coli ATCC 8739 6066966 YP_001725089.1 CDS EcolC_2122 NC_010468.1 2319372 2319764 D PFAM: conserved hypothetical protein; KEGG: ssn:SSON_1592 hypothetical protein; hypothetical protein 2319372..2319764 Escherichia coli ATCC 8739 6066932 YP_001725090.1 CDS EcolC_2123 NC_010468.1 2320019 2320909 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1593 hypothetical protein; hypothetical protein 2320019..2320909 Escherichia coli ATCC 8739 6066901 YP_001725091.1 CDS EcolC_2124 NC_010468.1 2321350 2322537 R YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE complement(2321350..2322537) Escherichia coli ATCC 8739 6066848 YP_001725092.1 CDS EcolC_2125 NC_010468.1 2322732 2323631 D PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: sfv:SFV_1593 hypothetical protein; O-acetylserine/cysteine export protein 2322732..2323631 Escherichia coli ATCC 8739 6065935 YP_001725093.1 CDS EcolC_2126 NC_010468.1 2323662 2323880 R KEGG: sbo:SBO_1650 multiple antibiotic resistance protein; hypothetical protein complement(2323662..2323880) Escherichia coli ATCC 8739 6065777 YP_001725094.1 CDS EcolC_2127 NC_010468.1 2323912 2324295 R transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA complement(2323912..2324295) Escherichia coli ATCC 8739 6065738 YP_001725095.1 CDS EcolC_2128 NC_010468.1 2324315 2324749 R Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR complement(2324315..2324749) Escherichia coli ATCC 8739 6065668 YP_001725096.1 CDS EcolC_2129 NC_010468.1 2324960 2325625 D protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 2324960..2325625 Escherichia coli ATCC 8739 6065465 YP_001725097.1 CDS EcolC_2130 NC_010468.1 2325650 2326840 R PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1646 putative resistance/regulatory protein; sugar efflux transporter complement(2325650..2326840) Escherichia coli ATCC 8739 6065410 YP_001725098.1 CDS EcolC_2131 NC_010468.1 2326990 2328105 R KEGG: sfx:S1694 hypothetical protein; hypothetical protein complement(2326990..2328105) Escherichia coli ATCC 8739 6065386 YP_001725099.1 CDS EcolC_2132 NC_010468.1 2328183 2329064 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sdy:SDY_1633 putative transcriptional regulator LysR-type; LysR family transcriptional regulator complement(2328183..2329064) Escherichia coli ATCC 8739 6065314 YP_001725100.1 CDS EcolC_2133 NC_010468.1 2329165 2330553 D in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate-semialdehyde dehydrogenase 2329165..2330553 Escherichia coli ATCC 8739 6065295 YP_001725101.1 CDS EcolC_2134 NC_010468.1 2330617 2331543 D catalyzes the formation of glutamate from glutamine; glutaminase 2330617..2331543 Escherichia coli ATCC 8739 6065265 YP_001725102.1 CDS EcolC_2135 NC_010468.1 2331543 2331902 D KEGG: sbo:SBO_1641 hypothetical protein; hypothetical protein 2331543..2331902 Escherichia coli ATCC 8739 6066342 YP_001725103.1 CDS EcolC_2136 NC_010468.1 2332014 2332961 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbo:SBO_1640 hypothetical protein; diguanylate cyclase 2332014..2332961 Escherichia coli ATCC 8739 6064781 YP_001725104.1 CDS EcolC_2137 NC_010468.1 2333187 2334638 D catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 2333187..2334638 Escherichia coli ATCC 8739 6067400 YP_001725105.1 CDS EcolC_2138 NC_010468.1 2334845 2335759 D PFAM: protein of unknown function UPF0187; KEGG: sfv:SFV_1577 hypothetical protein; hypothetical protein 2334845..2335759 Escherichia coli ATCC 8739 6065792 YP_001725106.1 CDS EcolC_2139 NC_010468.1 2335763 2336521 R catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase complement(2335763..2336521) Escherichia coli ATCC 8739 6066998 YP_001725107.1 CDS EcolC_2140 NC_010468.1 2336578 2336868 R PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sdy:SDY_1624 hypothetical protein; autoinducer-2 (AI-2) modifying protein LsrG complement(2336578..2336868) Escherichia coli ATCC 8739 6064446 YP_001725108.1 CDS EcolC_2141 NC_010468.1 2336892 2337767 R PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: stm:STM4078 putative fructose-1,6-bisphosphate aldolase; aldolase complement(2336892..2337767) Escherichia coli ATCC 8739 6065320 YP_001725109.1 CDS EcolC_2142 NC_010468.1 2337794 2338816 R KEGG: stm:STM4077 putative ABC superfamily (peri_perm), sugar transport protein; sugar ABC transporter periplasmic subunit complement(2337794..2338816) Escherichia coli ATCC 8739 6066233 YP_001725110.1 CDS EcolC_2143 NC_010468.1 2338828 2339820 R PFAM: inner-membrane translocator; KEGG: sfv:SFV_1570 putative transport system permease protein; monosaccharide-transporting ATPase complement(2338828..2339820) Escherichia coli ATCC 8739 6064726 YP_001725111.1 CDS EcolC_2144 NC_010468.1 2339820 2340848 R PFAM: inner-membrane translocator; KEGG: sfv:SFV_1569 putative transport system permease protein; monosaccharide-transporting ATPase complement(2339820..2340848) Escherichia coli ATCC 8739 6067128 YP_001725112.1 CDS EcolC_2145 NC_010468.1 2340842 2342377 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfv:SFV_1568 putative ATP-binding component of a transport system; ABC transporter-like protein complement(2340842..2342377) Escherichia coli ATCC 8739 6066507 YP_001725113.1 CDS EcolC_2146 NC_010468.1 2342626 2343579 D PFAM: putative sugar-binding domain protein; KEGG: sfv:SFV_1567 putative transcriptional regulator; DeoR family transcriptional regulator 2342626..2343579 Escherichia coli ATCC 8739 6064890 YP_001725114.1 CDS EcolC_2147 NC_010468.1 2343658 2345250 D PFAM: carbohydrate kinase FGGY; KEGG: stt:t3546 putative sugar kinase; autoinducer-2 (AI-2) kinase 2343658..2345250 Escherichia coli ATCC 8739 6066311 YP_001725115.1 CDS EcolC_2148 NC_010468.1 2345781 2351201 D TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ssn:SSON_1611 hypothetical protein; putative lipoprotein/autotransporter domain-containing protein 2345781..2351201 Escherichia coli ATCC 8739 6066806 YP_001725116.1 CDS EcolC_2149 NC_010468.1 2351424 2351690 D PFAM: helix-turn-helix domain protein; KEGG: ssn:SSON_1613 persistence to inhibition of murein or DNA biosynthesis; DNA-binding transcriptional regulator HipB 2351424..2351690 Escherichia coli ATCC 8739 6065560 YP_001725117.1 CDS EcolC_2150 NC_010468.1 2351690 2353012 D TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: kpn:KPN_01668 persistence to inhibition of murein or DNA biosynthesis, DNA-binding regulator; HipA domain-containing protein 2351690..2353012 Escherichia coli ATCC 8739 6066434 YP_001725118.1 CDS EcolC_2152 NC_010468.1 2353865 2355013 D PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: cko:CKO_03711 hypothetical protein; fimbrial biogenesis outer membrane usher protein 2353865..2355013 Escherichia coli ATCC 8739 6065540 YP_001725119.1 CDS EcolC_2153 NC_010468.1 2355027 2355557 D PFAM: Fimbrial protein; KEGG: cko:CKO_03712 hypothetical protein; fimbrial protein 2355027..2355557 Escherichia coli ATCC 8739 6064989 YP_001725120.1 CDS EcolC_2154 NC_010468.1 2355570 2356073 D PFAM: Fimbrial protein; KEGG: sbo:SBO_4369 fimbrial morphology; fimbrial protein 2355570..2356073 Escherichia coli ATCC 8739 6065065 YP_001725121.1 CDS EcolC_2155 NC_010468.1 2356132 2357046 D PFAM: Fimbrial protein ; FimH mannose-binding domain protein; KEGG: ssn:SSON_1621 putative adhesin; FimH mannose-binding domain-containing protein 2356132..2357046 Escherichia coli ATCC 8739 6064865 YP_001725122.1 CDS EcolC_2156 NC_010468.1 2357380 2359659 D in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase 2357380..2359659 Escherichia coli ATCC 8739 6065505 YP_001725123.1 CDS EcolC_2157 NC_010468.1 2359907 2360104 D KEGG: sfx:S1655 hypothetical protein; hypothetical protein 2359907..2360104 Escherichia coli ATCC 8739 6065599 YP_001725124.1 CDS EcolC_2158 NC_010468.1 2360179 2360940 D regulates the cellular response to acid resistance; transcriptional regulator YdeO 2360179..2360940 Escherichia coli ATCC 8739 6066249 YP_001725125.1 CDS EcolC_2159 NC_010468.1 2361342 2363024 D PFAM: sulfatase; KEGG: sbo:SBO_1558 putative sulfatase; sulfatase 2361342..2363024 Escherichia coli ATCC 8739 6065362 YP_001725126.1 CDS EcolC_2160 NC_010468.1 2363076 2364233 D PFAM: Radical SAM domain protein; KEGG: sfv:SFV_1723 putative enzyme; radical SAM domain-containing protein 2363076..2364233 Escherichia coli ATCC 8739 6065509 YP_001725127.1 CDS EcolC_2161 NC_010468.1 2364524 2366209 D PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_1627 putative ATP-binding component of a transport system; ABC transporter-like protein 2364524..2366209 Escherichia coli ATCC 8739 6066072 YP_001725128.1 CDS EcolC_2162 NC_010468.1 2366247 2368619 D PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1629 hypothetical protein; TonB-dependent receptor plug 2366247..2368619 Escherichia coli ATCC 8739 6067001 YP_001725129.1 CDS EcolC_2163 NC_010468.1 2368676 2371459 D PFAM: peptidase M16 domain protein; KEGG: sbo:SBO_1562 putative peptidase; peptidase M16 domain-containing protein 2368676..2371459 Escherichia coli ATCC 8739 6066999 YP_001725130.1 CDS EcolC_2164 NC_010468.1 2371821 2373221 D TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_1563 glutamate decarboxylase isozyme; glutamate decarboxylase 2371821..2373221 Escherichia coli ATCC 8739 6065829 YP_001725131.1 CDS EcolC_2165 NC_010468.1 2373377 2374912 D TIGRFAM: glutamate/g-aminobutyrate antiporter; PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1564 acid sensitivity protein, putative transporter; glutamate/g-aminobutyrate antiporter 2373377..2374912 Escherichia coli ATCC 8739 6066051 YP_001725132.1 CDS EcolC_2166 NC_010468.1 2375208 2376362 D PFAM: protein of unknown function DUF187; KEGG: ssn:SSON_1633 hypothetical protein; hypothetical protein 2375208..2376362 Escherichia coli ATCC 8739 6064948 YP_001725133.1 CDS EcolC_2167 NC_010468.1 2376734 2378116 D TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1634 hypothetical protein; diguanylate cyclase 2376734..2378116 Escherichia coli ATCC 8739 6067236 YP_001725134.1 CDS EcolC_2168 NC_010468.1 2378141 2380540 D heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 2378141..2380540 Escherichia coli ATCC 8739 6067485 YP_001725135.1 CDS EcolC_2169 NC_010468.1 2380798 2381379 D catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 2380798..2381379 Escherichia coli ATCC 8739 6066629 YP_001725136.1 CDS EcolC_2170 NC_010468.1 2381393 2382943 D PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1637 putative hemin-binding lipoprotein; extracellular solute-binding protein 2381393..2382943 Escherichia coli ATCC 8739 6067665 YP_001725137.1 CDS EcolC_2171 NC_010468.1 2382945 2383967 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1571 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein 2382945..2383967 Escherichia coli ATCC 8739 6066166 YP_001725138.1 CDS EcolC_2172 NC_010468.1 2383964 2384860 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1639 putative transport protein; ATP-dependent peptide transporter membrane subunit 2383964..2384860 Escherichia coli ATCC 8739 6065077 YP_001725139.1 CDS EcolC_2173 NC_010468.1 2384857 2385843 D KEGG: sbo:SBO_1573 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2384857..2385843 Escherichia coli ATCC 8739 6066381 YP_001725140.1 CDS EcolC_2174 NC_010468.1 2385836 2386762 D KEGG: sbo:SBO_1574 putative ATP-binding component of a transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2385836..2386762 Escherichia coli ATCC 8739 6065491 YP_001725141.1 CDS EcolC_2175 NC_010468.1 2386818 2387249 R PFAM: OsmC family protein; KEGG: sfv:SFV_1739 osmotically inducible protein; OsmC family protein complement(2386818..2387249) Escherichia coli ATCC 8739 6065102 YP_001725142.1 CDS EcolC_2176 NC_010468.1 2387594 2387809 D KEGG: sbo:SBO_1576 hypothetical protein; biofilm-dependent modulation protein 2387594..2387809 Escherichia coli ATCC 8739 6067469 YP_001725143.1 CDS rpsV NC_010468.1 2387911 2388048 D protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 2387911..2388048 Escherichia coli ATCC 8739 6065133 YP_001725144.1 CDS EcolC_2178 NC_010468.1 2388205 2389902 D malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 2388205..2389902 Escherichia coli ATCC 8739 6067594 YP_001725145.1 CDS EcolC_2179 NC_010468.1 2390036 2391046 D similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 2390036..2391046 Escherichia coli ATCC 8739 6065375 YP_001725146.1 CDS EcolC_2180 NC_010468.1 2391192 2391476 D TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sbo:SBO_1580 hypothetical protein; XRE family plasmid maintenance system antidote protein 2391192..2391476 Escherichia coli ATCC 8739 6066457 YP_001725147.1 CDS EcolC_2181 NC_010468.1 2391705 2392358 R nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma complement(2391705..2392358) Escherichia coli ATCC 8739 6066658 YP_001725148.1 CDS EcolC_2182 NC_010468.1 2392351 2393235 R TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbo:SBO_1582 formate dehydrogenase N, nitrate-inducible, iron-sulfur beta subunit; formate dehydrogenase subunit beta complement(2392351..2393235) Escherichia coli ATCC 8739 6065050 YP_001725149.1 CDS EcolC_2183 NC_010468.1 2393248 2396295 R KEGG: ssn:SSON_1650 formate dehydrogenase-N, nitrate-inducible, alpha subunit; Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; formate dehydrogenase subunit alpha complement(2393248..2396295) Escherichia coli ATCC 8739 6067466 YP_001725150.1 CDS EcolC_2184 NC_010468.1 2396584 2397408 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_1651 hypothetical protein; hypothetical protein 2396584..2397408 Escherichia coli ATCC 8739 6065629 YP_001725151.1 CDS EcolC_2185 NC_010468.1 2397667 2397957 D KEGG: sbo:SBO_1585 putative outer membrane porin protein; putative outer membrane porin protein 2397667..2397957 Escherichia coli ATCC 8739 6064772 YP_001725152.1 CDS EcolC_2186 NC_010468.1 2398017 2399312 D KEGG: sfv:SFV_1753 putative glycoportein; hypothetical protein 2398017..2399312 Escherichia coli ATCC 8739 6066536 YP_001725153.1 CDS EcolC_2187 NC_010468.1 2399636 2401024 D TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_1756 nitrite extrusion protein 2; nitrite transporter 2399636..2401024 Escherichia coli ATCC 8739 6066539 YP_001725154.1 CDS EcolC_2188 NC_010468.1 2401106 2404846 D TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1757 cryptic nitrate reductase 2, alpha subunit; nitrate reductase subunit alpha 2401106..2404846 Escherichia coli ATCC 8739 6066028 YP_001725155.1 CDS EcolC_2189 NC_010468.1 2404843 2406387 D TIGRFAM: nitrate reductase, beta subunit; KEGG: ssn:SSON_1658 cryptic nitrate reductase 2, beta subunit; nitrate reductase subunit beta 2404843..2406387 Escherichia coli ATCC 8739 6066070 YP_001725156.1 CDS EcolC_2190 NC_010468.1 2406387 2407082 D TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: ssn:SSON_1659 cryptic nitrate reductase 2, delta subunit, assembly function; nitrate reductase molybdenum cofactor assembly chaperone 2406387..2407082 Escherichia coli ATCC 8739 6066332 YP_001725157.1 CDS EcolC_2191 NC_010468.1 2407079 2407759 D KEGG: sdy:SDY_1653 cryptic nitrate reductase 2, gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit; respiratory nitrate reductase subunit gamma 2407079..2407759 Escherichia coli ATCC 8739 6066461 YP_001725158.1 CDS EcolC_2192 NC_010468.1 2407838 2408731 D TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: sdy:SDY_1654 hypothetical protein; hypothetical protein 2407838..2408731 Escherichia coli ATCC 8739 6066977 YP_001725159.1 CDS EcolC_2193 NC_010468.1 2408827 2409672 R PFAM: N-acetyltransferase; KEGG: ssn:SSON_1662 putative N-hydroxyarylamine O-acetyltransferase; N-hydroxyarylamine O-acetyltransferase complement(2408827..2409672) Escherichia coli ATCC 8739 6066160 YP_001725160.1 CDS EcolC_2194 NC_010468.1 2409845 2410414 D PFAM: flavin reductase domain protein FMN-binding; KEGG: ssn:SSON_1663 hypothetical protein; flavin reductase domain-containing protein 2409845..2410414 Escherichia coli ATCC 8739 6066046 YP_001725161.1 CDS EcolC_2195 NC_010468.1 2410418 2410645 R 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase complement(2410418..2410645) Escherichia coli ATCC 8739 6065514 YP_001725162.1 CDS EcolC_2196 NC_010468.1 2410678 2411469 R PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein complement(2410678..2411469) Escherichia coli ATCC 8739 6065512 YP_001725163.1 CDS EcolC_2197 NC_010468.1 2411676 2412998 R PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; KEGG: lpc:LPC_1850 reverse transcriptase; RNA-directed DNA polymerase complement(2411676..2412998) Escherichia coli ATCC 8739 6064974 YP_001725164.1 CDS EcolC_2198 NC_010468.1 2413524 2413898 R hypothetical protein complement(2413524..2413898) Escherichia coli ATCC 8739 6065033 YP_001725165.1 CDS EcolC_2200 NC_010468.1 2415395 2416092 D PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein join(2415395..2415649,2415649..2416092) Escherichia coli ATCC 8739 6065446 YP_001725166.1 CDS EcolC_2201 NC_010468.1 2416103 2419909 R TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(2416103..2419909) Escherichia coli ATCC 8739 6064804 YP_001725167.1 CDS EcolC_2202 NC_010468.1 2419976 2422084 R TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ssn:SSON_1677 unknown protein associated with rhs element; ImpA family type VI secretion-associated protein complement(2419976..2422084) Escherichia coli ATCC 8739 6064823 YP_001725168.1 CDS EcolC_2203 NC_010468.1 2422154 2423290 R PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein complement(2422154..2423290) Escherichia coli ATCC 8739 6064820 YP_001725169.1 CDS EcolC_2204 NC_010468.1 2424206 2424406 R KEGG: ssn:SSON_1678 hypothetical protein; hypothetical protein complement(2424206..2424406) Escherichia coli ATCC 8739 6064850 YP_001725170.1 CDS EcolC_2205 NC_010468.1 2424494 2425093 R KEGG: sbo:SBO_1593 putative transferase; putative transferase complement(2424494..2425093) Escherichia coli ATCC 8739 6066578 YP_001725171.1 CDS EcolC_2206 NC_010468.1 2425359 2426858 D PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1594 L-asparagine permease; amino acid permease-associated protein 2425359..2426858 Escherichia coli ATCC 8739 6065679 YP_001725172.1 CDS EcolC_2207 NC_010468.1 2426973 2428034 R KEGG: sbo:SBO_1595 putative receptor; putative receptor complement(2426973..2428034) Escherichia coli ATCC 8739 6065879 YP_001725173.1 CDS EcolC_2208 NC_010468.1 2428276 2430378 D PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1682 putative outer membrane receptor for iron transport; TonB-dependent receptor 2428276..2430378 Escherichia coli ATCC 8739 6067101 YP_001725174.1 CDS EcolC_2209 NC_010468.1 2430414 2431079 R PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfv:SFV_1761 hypothetical protein; putative DNA-binding transcriptional regulator complement(2430414..2431079) Escherichia coli ATCC 8739 6065537 YP_001725175.1 CDS EcolC_2210 NC_010468.1 2431277 2432314 R PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1762 putative oxidoreductase; alcohol dehydrogenase complement(2431277..2432314) Escherichia coli ATCC 8739 6065464 YP_001725176.1 CDS EcolC_2211 NC_010468.1 2432495 2433013 D PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_1688 putative resistance protein; N-acetyltransferase GCN5 2432495..2433013 Escherichia coli ATCC 8739 6066866 YP_001725177.1 CDS EcolC_2212 NC_010468.1 2433010 2433459 D PFAM: protein of unknown function DUF606; KEGG: sbo:SBO_1601 hypothetical protein; hypothetical protein 2433010..2433459 Escherichia coli ATCC 8739 6064447 YP_001725178.1 CDS EcolC_2213 NC_010468.1 2433460 2433693 R KEGG: sbo:SBO_1602 hypothetical protein; hypothetical protein complement(2433460..2433693) Escherichia coli ATCC 8739 6066291 YP_001725179.1 CDS EcolC_2214 NC_010468.1 2433779 2434000 R KEGG: sdy:SDY_1729 hypothetical protein; hypothetical protein complement(2433779..2434000) Escherichia coli ATCC 8739 6064860 YP_001725180.1 CDS EcolC_2215 NC_010468.1 2434339 2435763 R catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase complement(2434339..2435763) Escherichia coli ATCC 8739 6067156 YP_001725181.1 CDS EcolC_2216 NC_010468.1 2435785 2436579 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_1771 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein complement(2435785..2436579) Escherichia coli ATCC 8739 6066400 YP_001725182.1 CDS EcolC_2217 NC_010468.1 2436569 2437510 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ent:Ent638_2126 binding-protein-dependent transport systems inner membrane component; binding-protein-dependent transport system inner membrane protein complement(2436569..2437510) Escherichia coli ATCC 8739 6065455 YP_001725183.1 CDS EcolC_2218 NC_010468.1 2437511 2438524 R PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ssn:SSON_1696 putative ATP-binding component of a transport system; ABC transporter-like protein complement(2437511..2438524) Escherichia coli ATCC 8739 6065331 YP_001725184.1 CDS EcolC_2219 NC_010468.1 2438542 2439687 R PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1697 putative transport protein; extracellular solute-binding protein complement(2438542..2439687) Escherichia coli ATCC 8739 6064924 YP_001725185.1 CDS EcolC_2220 NC_010468.1 2439932 2441338 R PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: ssn:SSON_1698 multi modular; putative transcriptional regulator; also putative ATP-binding component of a transport system; transcriptional regulator complement(2439932..2441338) Escherichia coli ATCC 8739 6065260 YP_001725186.1 CDS EcolC_2221 NC_010468.1 2441417 2441854 R PFAM: helix-turn-helix domain protein; protein of unknown function UPF0150; KEGG: sdy:SDY_1736 hypothetical protein; XRE family transcriptional regulator complement(2441417..2441854) Escherichia coli ATCC 8739 6066919 YP_001725187.1 CDS EcolC_2222 NC_010468.1 2441879 2442055 R PFAM: YcfA family protein; KEGG: cko:CKO_01475 hypothetical protein; hypothetical protein complement(2441879..2442055) Escherichia coli ATCC 8739 6065542 YP_001725188.1 CDS EcolC_2223 NC_010468.1 2442277 2442507 D KEGG: ssn:SSON_1702 hypothetical protein; hypothetical protein 2442277..2442507 Escherichia coli ATCC 8739 6065696 YP_001725189.1 CDS EcolC_2224 NC_010468.1 2442599 2444602 R PFAM: peptidase U32; KEGG: ssn:SSON_1703 putative collagenase; peptidase U32 complement(2442599..2444602) Escherichia coli ATCC 8739 6064980 YP_001725190.1 CDS EcolC_2225 NC_010468.1 2444633 2445169 R PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: ssn:SSON_1704 hypothetical protein; XRE family transcriptional regulator complement(2444633..2445169) Escherichia coli ATCC 8739 6066356 YP_001725191.1 CDS EcolC_2226 NC_010468.1 2445261 2446436 D TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: cko:CKO_01471 hypothetical protein; benzoate transporter 2445261..2446436 Escherichia coli ATCC 8739 6066830 YP_001725192.1 CDS EcolC_2227 NC_010468.1 2446476 2447624 R KEGG: ssn:SSON_1709 putative virulence protein; TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; IS605 family transposase OrfB complement(2446476..2447624) Escherichia coli ATCC 8739 6066563 YP_001725193.1 CDS EcolC_2229 NC_010468.1 2448216 2448884 R KEGG: sfv:SFV_1775 hypothetical protein; hypothetical protein complement(2448216..2448884) Escherichia coli ATCC 8739 6066043 YP_001725194.1 CDS EcolC_2230 NC_010468.1 2449187 2449780 R with TehA confers resistance to tellurite; tellurite resistance protein TehB complement(2449187..2449780) Escherichia coli ATCC 8739 6065770 YP_001725195.1 CDS EcolC_2231 NC_010468.1 2449777 2450769 R PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: sfv:SFV_1777 tellurite resistance; potassium-tellurite ethidium and proflavin transporter complement(2449777..2450769) Escherichia coli ATCC 8739 6066500 YP_001725196.1 CDS EcolC_2232 NC_010468.1 2450893 2451873 D KEGG: sfv:SFV_1778 hypothetical protein; hypothetical protein 2450893..2451873 Escherichia coli ATCC 8739 6066909 YP_001725197.1 CDS EcolC_2233 NC_010468.1 2451868 2452404 R PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_1660 acetyl transferase; ribosomal-protein-L7/L12-serine acetyltransferase complement(2451868..2452404) Escherichia coli ATCC 8739 6067336 YP_001725198.1 CDS EcolC_2234 NC_010468.1 2452467 2452691 R PFAM: protein of unknown function DUF465; KEGG: sfv:SFV_1780 hypothetical protein; hypothetical protein complement(2452467..2452691) Escherichia coli ATCC 8739 6066348 YP_001725199.1 CDS mdoD NC_010468.1 2452831 2454450 R involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D complement(2452831..2454450) Escherichia coli ATCC 8739 6065912 YP_001725200.1 CDS EcolC_2236 NC_010468.1 2454711 2456054 R PFAM: protein of unknown function DUF1338; KEGG: sdy:SDY_1757 hypothetical protein; hypothetical protein complement(2454711..2456054) Escherichia coli ATCC 8739 6066347 YP_001725201.1 CDS EcolC_2237 NC_010468.1 2456175 2457194 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1720 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2456175..2457194 Escherichia coli ATCC 8739 6067319 YP_001725202.1 CDS EcolC_2238 NC_010468.1 2457232 2458872 R PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ssn:SSON_1721 methyl-accepting chemotaxis protein III; methyl-accepting chemotaxis sensory transducer complement(2457232..2458872) Escherichia coli ATCC 8739 6067316 YP_001725203.1 CDS EcolC_2239 NC_010468.1 2459271 2459420 D PFAM: Hok/gef cell toxic protein; KEGG: ent:Ent638_4258 Hok/gef cell toxic protein; small toxic polypeptide 2459271..2459420 Escherichia coli ATCC 8739 6067599 YP_001725204.1 CDS EcolC_2240 NC_010468.1 2459492 2459665 R KEGG: ssn:SSON_1723 hypothetical protein; hypothetical protein complement(2459492..2459665) Escherichia coli ATCC 8739 6065007 YP_001725205.1 CDS EcolC_2241 NC_010468.1 2459910 2460440 R B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 complement(2459910..2460440) Escherichia coli ATCC 8739 6065457 YP_001725206.1 CDS EcolC_2242 NC_010468.1 2460629 2461630 D KEGG: ssn:SSON_1725 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 2460629..2461630 Escherichia coli ATCC 8739 6064371 YP_001725207.1 CDS EcolC_2243 NC_010468.1 2461672 2463111 R NAD-linked; aldehyde dehydrogenase A complement(2461672..2463111) Escherichia coli ATCC 8739 6067691 YP_001725208.1 CDS EcolC_2244 NC_010468.1 2463308 2464108 R PFAM: protein of unknown function DUF218; KEGG: sbo:SBO_1673 hypothetical protein; hypothetical protein complement(2463308..2464108) Escherichia coli ATCC 8739 6065871 YP_001725209.1 CDS EcolC_2245 NC_010468.1 2464380 2468282 R involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA complement(2464380..2468282) Escherichia coli ATCC 8739 6066961 YP_001725210.1 CDS EcolC_2246 NC_010468.1 2468483 2469088 D FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 2468483..2469088 Escherichia coli ATCC 8739 6066957 YP_001725211.1 CDS EcolC_2247 NC_010468.1 2469142 2470458 R PFAM: phosphoesterase PA-phosphatase related; Dual specificity protein phosphatase; SMART: Protein-tyrosine phosphatase, catalytic; KEGG: sbo:SBO_1676 putative enzyme; putative dual specificity phosphatase complement(2469142..2470458) Escherichia coli ATCC 8739 6066948 YP_001725212.1 CDS EcolC_2248 NC_010468.1 2470448 2472205 R KEGG: sdy:SDY_1779 hypothetical protein; hypothetical protein complement(2470448..2472205) Escherichia coli ATCC 8739 6066943 YP_001725213.1 CDS EcolC_2249 NC_010468.1 2472221 2473117 R PFAM: phosphatidate cytidylyltransferase; KEGG: sfx:S1465 putative phosphatidate cytidiltransferase; phosphatidate cytidylyltransferase complement(2472221..2473117) Escherichia coli ATCC 8739 6065855 YP_001725214.1 CDS EcolC_2250 NC_010468.1 2473117 2473722 R PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfv:SFV_1801 probable enzyme; CDP-alcohol phosphatidyltransferase complement(2473117..2473722) Escherichia coli ATCC 8739 6066104 YP_001725215.1 CDS EcolC_2251 NC_010468.1 2473893 2476199 R KEGG: sfv:SFV_1802 hypothetical protein; hypothetical protein complement(2473893..2476199) Escherichia coli ATCC 8739 6066938 YP_001725216.1 CDS EcolC_2252 NC_010468.1 2476263 2477123 R PFAM: aldo/keto reductase; KEGG: cko:CKO_01438 hypothetical protein; putative oxidoreductase complement(2476263..2477123) Escherichia coli ATCC 8739 6067705 YP_001725217.1 CDS EcolC_2254 NC_010468.1 2480835 2481986 R PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30; integrase catalytic subunit complement(2480835..2481986) Escherichia coli ATCC 8739 6066951 YP_001725218.1 CDS EcolC_2255 NC_010468.1 2485829 2486419 R TIGRFAM: phenylacetic acid degradation protein PaaY; KEGG: kpn:KPN_01481 phenylacetic acid degradation protein; putative transferase; phenylacetic acid degradation protein PaaY complement(2485829..2486419) Escherichia coli ATCC 8739 6066936 YP_001725219.1 CDS EcolC_2256 NC_010468.1 2486401 2487351 R TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: kpn:KPN_01480 transcriptional repressor for phenylacetic acid degradation; PaaX family transcriptional regulator complement(2486401..2487351) Escherichia coli ATCC 8739 6067050 YP_001725220.1 CDS EcolC_2257 NC_010468.1 2487452 2488765 R TIGRFAM: phenylacetate-CoA ligase; KEGG: kpn:KPN_01479 phenylacetate-CoA ligase; phenylacetate-CoA ligase complement(2487452..2488765) Escherichia coli ATCC 8739 6067057 YP_001725221.1 CDS EcolC_2258 NC_010468.1 2488792 2489997 R catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase complement(2488792..2489997) Escherichia coli ATCC 8739 6067052 YP_001725222.1 CDS EcolC_2259 NC_010468.1 2489997 2490419 R TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; KEGG: kpn:KPN_01477 phenylacetic acid degradation protein; phenylacetic acid degradation protein PaaD complement(2489997..2490419) Escherichia coli ATCC 8739 6067051 YP_001725223.1 CDS EcolC_2260 NC_010468.1 2490409 2491836 R converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase complement(2490409..2491836) Escherichia coli ATCC 8739 6067047 YP_001725224.1 CDS EcolC_2261 NC_010468.1 2491838 2492626 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(2491838..2492626) Escherichia coli ATCC 8739 6067041 YP_001725225.1 CDS EcolC_2262 NC_010468.1 2492626 2493393 R PFAM: Enoyl-CoA hydratase/isomerase; KEGG: kpn:KPN_01474 probable enoyl-CoA hydratase; enoyl-CoA hydratase-isomerase complement(2492626..2493393) Escherichia coli ATCC 8739 6067042 YP_001725226.1 CDS EcolC_2263 NC_010468.1 2493390 2494460 R TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: kpn:KPN_01473 probable phenylacetic acid degradation NADH oxidoreductase; phenylacetate-CoA oxygenase/reductase subunit PaaK complement(2493390..2494460) Escherichia coli ATCC 8739 6067034 YP_001725227.1 CDS EcolC_2264 NC_010468.1 2494468 2494965 R TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: kpn:KPN_01472 phenylacetic acid degradation protein; phenylacetate-CoA oxygenase subunit PaaJ complement(2494468..2494965) Escherichia coli ATCC 8739 6068712 YP_001725228.1 CDS EcolC_2265 NC_010468.1 2494980 2495726 R TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; KEGG: kpn:KPN_01471 phenylacetic acid degradation protein; phenylacetate-CoA oxygenase subunit PaaI complement(2494980..2495726) Escherichia coli ATCC 8739 6064432 YP_001725229.1 CDS paaB NC_010468.1 2495735 2496022 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB complement(2495735..2496022) Escherichia coli ATCC 8739 6065459 YP_001725230.1 CDS paaA NC_010468.1 2496034 2496963 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA complement(2496034..2496963) Escherichia coli ATCC 8739 6067026 YP_001725231.1 CDS EcolC_2268 NC_010468.1 2497248 2499293 D catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 2497248..2499293 Escherichia coli ATCC 8739 6067021 YP_001725232.1 CDS tynA NC_010468.1 2499541 2501814 D catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 2499541..2501814 Escherichia coli ATCC 8739 6067016 YP_001725233.1 CDS EcolC_2270 NC_010468.1 2501873 2503372 R PFAM: Aldehyde Dehydrogenase_; KEGG: kpn:KPN_01455 phenylacetaldehyde dehydrogenase; phenylacetaldehyde dehydrogenase complement(2501873..2503372) Escherichia coli ATCC 8739 6067018 YP_001725234.1 CDS EcolC_2271 NC_010468.1 2503608 2504513 D activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 2503608..2504513 Escherichia coli ATCC 8739 6067011 YP_001725235.1 CDS EcolC_2272 NC_010468.1 2504685 2505011 R PFAM: conserved hypothetical protein; KEGG: sbo:SBO_1683 hypothetical protein; hypothetical protein complement(2504685..2505011) Escherichia coli ATCC 8739 6067007 YP_001725236.1 CDS EcolC_2273 NC_010468.1 2505019 2505204 R KEGG: ssn:SSON_1742 hypothetical protein; hypothetical protein complement(2505019..2505204) Escherichia coli ATCC 8739 6067003 YP_001725237.1 CDS EcolC_2274 NC_010468.1 2505201 2507840 R KEGG: sbo:SBO_1685 hypothetical protein; hypothetical protein complement(2505201..2507840) Escherichia coli ATCC 8739 6068693 YP_001725238.1 CDS EcolC_2275 NC_010468.1 2508048 2509037 D PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1744 fermentative D-lactate dehydrogenase, NAD-dependent; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase 2508048..2509037 Escherichia coli ATCC 8739 6066995 YP_001725239.1 CDS EcolC_2276 NC_010468.1 2509148 2509570 D PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sbo:SBO_1687 heat shock protein HslJ; heat-inducible protein 2509148..2509570 Escherichia coli ATCC 8739 6066984 YP_001725240.1 CDS EcolC_2277 NC_010468.1 2509567 2509833 R KEGG: sdy:SDY_1462 hypothetical protein; hypothetical protein complement(2509567..2509833) Escherichia coli ATCC 8739 6066982 YP_001725241.1 CDS EcolC_2278 NC_010468.1 2510107 2513631 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sbo:SBO_1688 putative oxidoreductase, Fe-S subunit; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 2510107..2513631 Escherichia coli ATCC 8739 6066979 YP_001725242.1 CDS EcolC_2279 NC_010468.1 2513998 2515131 D PFAM: porin Gram-negative type; KEGG: sbo:SBO_1689 putative outer membrane protein; porin 2513998..2515131 Escherichia coli ATCC 8739 6068729 YP_001725243.1 CDS EcolC_2280 NC_010468.1 2515272 2515706 D PFAM: UspA domain protein; KEGG: sdy:SDY_1458 putative filament protein; UspA domain-containing protein 2515272..2515706 Escherichia coli ATCC 8739 6066970 YP_001725244.1 CDS EcolC_2281 NC_010468.1 2515883 2516818 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 2515883..2516818 Escherichia coli ATCC 8739 6066968 YP_001725245.1 CDS EcolC_2282 NC_010468.1 2516947 2518320 R exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA complement(2516947..2518320) Escherichia coli ATCC 8739 6066967 YP_001725246.1 CDS zntB NC_010468.1 2518798 2519781 R PFAM: Mg2 transporter protein CorA family protein; KEGG: sdy:SDY_1424 hypothetical protein; zinc transporter complement(2518798..2519781) Escherichia coli ATCC 8739 6066965 YP_001725247.1 CDS EcolC_2284 NC_010468.1 2520036 2521268 D KEGG: sbo:SBO_1720 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAS/PAC sensor-containing diguanylate cyclase 2520036..2521268 Escherichia coli ATCC 8739 6064355 YP_001725248.1 CDS EcolC_2285 NC_010468.1 2521289 2521852 R PFAM: Smr protein/MutS2; KEGG: ssn:SSON_1791 hypothetical protein; Smr protein/MutS2 complement(2521289..2521852) Escherichia coli ATCC 8739 6064364 YP_001725249.1 CDS EcolC_2286 NC_010468.1 2522182 2523090 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_1792 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator complement(2522182..2523090) Escherichia coli ATCC 8739 6066962 YP_001725250.1 CDS EcolC_2287 NC_010468.1 2523266 2524576 D TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1793 putative aminohydrolase; amidohydrolase 2523266..2524576 Escherichia coli ATCC 8739 6066959 YP_001725251.1 CDS EcolC_2288 NC_010468.1 2524576 2526021 D TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1794 hypothetical protein; amidohydrolase 2524576..2526021 Escherichia coli ATCC 8739 6066958 YP_001725252.1 CDS abgT NC_010468.1 2526055 2527581 D TIGRFAM: AbgT transporter family; PFAM: AbgT putative transporter; KEGG: sbo:SBO_1725 putative pump protein (transport); putative aminobenzoyl-glutamate transporter 2526055..2527581 Escherichia coli ATCC 8739 6065413 YP_001725253.1 CDS EcolC_2290 NC_010468.1 2527592 2528107 D KEGG: sfv:SFV_1824 O-6-alkylguanine-DNA/cysteine-protein methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 2527592..2528107 Escherichia coli ATCC 8739 6068733 YP_001725254.1 CDS EcolC_2291 NC_010468.1 2528302 2529054 D Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 2528302..2529054 Escherichia coli ATCC 8739 6066838 YP_001725255.1 CDS EcolC_2292 NC_010468.1 2529206 2530156 D with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 2529206..2530156 Escherichia coli ATCC 8739 6066955 YP_001725256.1 CDS EcolC_2293 NC_010468.1 2530206 2530463 R KEGG: ssn:SSON_1801 hypothetical protein; hypothetical protein complement(2530206..2530463) Escherichia coli ATCC 8739 6066947 YP_001725257.1 CDS EcolC_2294 NC_010468.1 2530707 2531738 D PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_1732 hypothetical protein; mechanosensitive ion channel MscS 2530707..2531738 Escherichia coli ATCC 8739 6066869 YP_001725258.1 CDS EcolC_2295 NC_010468.1 2531789 2533402 R PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1804 putative transport periplasmic protein; extracellular solute-binding protein complement(2531789..2533402) Escherichia coli ATCC 8739 6068731 YP_001725259.1 CDS EcolC_2296 NC_010468.1 2533739 2534638 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_1734 putative transcriptional regulator LysR-type; LysR family transcriptional regulator complement(2533739..2534638) Escherichia coli ATCC 8739 6066941 YP_001725260.1 CDS EcolC_2297 NC_010468.1 2534776 2535696 D PFAM: peptidase S15; KEGG: sfl:SF1337 hypothetical protein; peptidase S15 2534776..2535696 Escherichia coli ATCC 8739 6066935 YP_001725261.1 CDS EcolC_2299 NC_010468.1 2536032 2536760 D PFAM: peptidase M14 carboxypeptidase A; KEGG: sbo:SBO_1744 putative carboxypeptidase; murein peptide amidase A 2536032..2536760 Escherichia coli ATCC 8739 6067056 YP_001725262.1 CDS EcolC_2300 NC_010468.1 2536735 2537700 R PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: sfv:SFV_1341 putative muconate cycloisomerase I; mandelate racemase/muconate lactonizing protein complement(2536735..2537700) Escherichia coli ATCC 8739 6066945 YP_001725263.1 CDS tpx NC_010468.1 2537819 2538325 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2537819..2538325 Escherichia coli ATCC 8739 6067015 YP_001725264.1 CDS EcolC_2302 NC_010468.1 2538369 2539910 R regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR complement(2538369..2539910) Escherichia coli ATCC 8739 6066954 YP_001725265.1 CDS EcolC_2303 NC_010468.1 2540058 2541119 R PFAM: conserved hypothetical protein; KEGG: sfv:SFV_1338 hypothetical protein; hypothetical protein complement(2540058..2541119) Escherichia coli ATCC 8739 6067006 YP_001725266.1 CDS EcolC_2304 NC_010468.1 2541116 2542513 R PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: sbo:SBO_1749 YcjX; hypothetical protein complement(2541116..2542513) Escherichia coli ATCC 8739 6066975 YP_001725267.1 CDS EcolC_2305 NC_010468.1 2542669 2543667 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sfx:S1409 putative LacI-type transcriptional regulator; LacI family transcriptional regulator 2542669..2543667 Escherichia coli ATCC 8739 6066937 YP_001725268.1 CDS EcolC_2306 NC_010468.1 2543778 2544683 R KEGG: ent:Ent638_2156 outer membrane protein G precursor; outer membrane protein G complement(2543778..2544683) Escherichia coli ATCC 8739 6066929 YP_001725269.1 CDS EcolC_2307 NC_010468.1 2544728 2545810 R PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sfv:SFV_1334 putative ATP-binding component of a transport system; ABC transporter-like protein complement(2544728..2545810) Escherichia coli ATCC 8739 6068307 YP_001725270.1 CDS EcolC_2308 NC_010468.1 2545824 2546483 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ssn:SSON_1823 putative beta-phosphoglucomutase; beta-phosphoglucomutase complement(2545824..2546483) Escherichia coli ATCC 8739 6067488 YP_001725271.1 CDS EcolC_2309 NC_010468.1 2546480 2548747 R PFAM: glycoside hydrolase family 65 domain protein; glycoside hydrolase family 65 central catalytic; KEGG: ssn:SSON_1824 hypothetical protein; Kojibiose phosphorylase complement(2546480..2548747) Escherichia coli ATCC 8739 6068708 YP_001725272.1 CDS EcolC_2310 NC_010468.1 2548744 2549799 R PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ssn:SSON_1825 putative dehydrogenase; oxidoreductase domain-containing protein complement(2548744..2549799) Escherichia coli ATCC 8739 6065658 YP_001725273.1 CDS EcolC_2311 NC_010468.1 2549809 2550597 R PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ssn:SSON_1826 putative transient receptor potential locus; xylose isomerase domain-containing protein complement(2549809..2550597) Escherichia coli ATCC 8739 6064564 YP_001725274.1 CDS EcolC_2312 NC_010468.1 2550616 2551668 R PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1329 putative oxidoreductase; alcohol dehydrogenase complement(2550616..2551668) Escherichia coli ATCC 8739 6067040 YP_001725275.1 CDS EcolC_2313 NC_010468.1 2551699 2552541 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_1328 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein complement(2551699..2552541) Escherichia coli ATCC 8739 6066886 YP_001725276.1 CDS EcolC_2314 NC_010468.1 2552528 2553409 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1829 putative binding-protein dependent transport protein; binding-protein-dependent transport system inner membrane protein complement(2552528..2553409) Escherichia coli ATCC 8739 6066695 YP_001725277.1 CDS EcolC_2315 NC_010468.1 2553430 2554722 R PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1830 putative transport periplasmic protein; extracellular solute-binding protein complement(2553430..2554722) Escherichia coli ATCC 8739 6065983 YP_001725278.1 CDS EcolC_2316 NC_010468.1 2554736 2556415 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ent:Ent638_2165 alpha amylase, catalytic region; alpha amylase complement(2554736..2556415) Escherichia coli ATCC 8739 6065908 YP_001725279.1 CDS EcolC_2317 NC_010468.1 2556628 2556942 R rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase complement(2556628..2556942) Escherichia coli ATCC 8739 6065440 YP_001725280.1 CDS EcolC_2318 NC_010468.1 2557017 2557238 R TIGRFAM: phage shock protein PspD; PFAM: shock protein PspD; KEGG: sdy:SDY_1937 phage shock protein; peripheral inner membrane phage-shock protein complement(2557017..2557238) Escherichia coli ATCC 8739 6064838 YP_001725281.1 CDS EcolC_2319 NC_010468.1 2557247 2557606 R with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC complement(2557247..2557606) Escherichia coli ATCC 8739 6065789 YP_001725282.1 CDS pspB NC_010468.1 2557606 2557830 R acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B complement(2557606..2557830) Escherichia coli ATCC 8739 6064745 YP_001725283.1 CDS EcolC_2321 NC_010468.1 2557884 2558552 R involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA complement(2557884..2558552) Escherichia coli ATCC 8739 6065182 YP_001725284.1 CDS pspF NC_010468.1 2558719 2559696 D transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 2558719..2559696 Escherichia coli ATCC 8739 6067094 YP_001725285.1 CDS EcolC_2323 NC_010468.1 2559816 2561081 R putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase complement(2559816..2561081) Escherichia coli ATCC 8739 6066303 YP_001725286.1 CDS EcolC_2324 NC_010468.1 2561119 2562399 R PFAM: FAD dependent oxidoreductase; KEGG: ssn:SSON_1839 probable oxidoreductase; FAD dependent oxidoreductase complement(2561119..2562399) Escherichia coli ATCC 8739 6066648 YP_001725287.1 CDS EcolC_2325 NC_010468.1 2562401 2563888 R catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase complement(2562401..2563888) Escherichia coli ATCC 8739 6067383 YP_001725288.1 CDS EcolC_2326 NC_010468.1 2564163 2564720 R regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR complement(2564163..2564720) Escherichia coli ATCC 8739 6065253 YP_001725289.1 CDS puuD NC_010468.1 2564747 2565511 R catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase complement(2564747..2565511) Escherichia coli ATCC 8739 6065753 YP_001725290.1 CDS EcolC_2328 NC_010468.1 2565723 2567141 D PFAM: glutamine synthetase catalytic region; KEGG: sfx:S1384 putative glutamine synthetase; glutamine synthetase 2565723..2567141 Escherichia coli ATCC 8739 6065435 YP_001725291.1 CDS EcolC_2329 NC_010468.1 2567444 2568829 D PFAM: amino acid permease-associated region; KEGG: sbo:SBO_1766 putative amino acid/amine transport protein; amino acid permease-associated protein 2567444..2568829 Escherichia coli ATCC 8739 6065083 YP_001725292.1 CDS EcolC_2330 NC_010468.1 2568963 2569208 D KEGG: ssn:SSON_1845 hypothetical protein; hypothetical protein 2568963..2569208 Escherichia coli ATCC 8739 6065237 YP_001725293.1 CDS EcolC_2331 NC_010468.1 2569521 2571164 D PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1768 SapA; extracellular solute-binding protein 2569521..2571164 Escherichia coli ATCC 8739 6066752 YP_001725294.1 CDS EcolC_2332 NC_010468.1 2571161 2572126 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1769 SapB; binding-protein-dependent transport system inner membrane protein 2571161..2572126 Escherichia coli ATCC 8739 6068715 YP_001725295.1 CDS EcolC_2333 NC_010468.1 2572113 2573003 D PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1770 SapC; binding-protein-dependent transport system inner membrane protein 2572113..2573003 Escherichia coli ATCC 8739 6067196 YP_001725296.1 CDS EcolC_2334 NC_010468.1 2573003 2573995 D KEGG: ssn:SSON_1849 putative ATP-binding protein of peptide transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase 2573003..2573995 Escherichia coli ATCC 8739 6065568 YP_001725297.1 CDS EcolC_2335 NC_010468.1 2573997 2574803 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_1772 putative ATP-binding protein of peptide transport system; ABC transporter-like protein 2573997..2574803 Escherichia coli ATCC 8739 6066077 YP_001725298.1 CDS EcolC_2336 NC_010468.1 2574871 2575224 D PFAM: protein of unknown function DUF559; KEGG: sbo:SBO_1773 hypothetical protein; hypothetical protein 2574871..2575224 Escherichia coli ATCC 8739 6066441 YP_001725299.1 CDS EcolC_2337 NC_010468.1 2575592 2576380 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 2575592..2576380 Escherichia coli ATCC 8739 6067615 YP_001725300.1 CDS EcolC_2338 NC_010468.1 2576524 2577651 D KEGG: sbo:SBO_1775 putative oxidoreductase; putative oxidoreductase 2576524..2577651 Escherichia coli ATCC 8739 6064690 YP_001725301.1 CDS EcolC_2339 NC_010468.1 2577719 2579653 D Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 2577719..2579653 Escherichia coli ATCC 8739 6065623 YP_001725302.1 CDS EcolC_2340 NC_010468.1 2579887 2581872 D c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 2579887..2581872 Escherichia coli ATCC 8739 6064427 YP_001725303.1 CDS EcolC_2341 NC_010468.1 2582019 2582192 D KEGG: sdy:SDY_1362 hypothetical protein; hypothetical protein 2582019..2582192 Escherichia coli ATCC 8739 6064681 YP_001725304.1 CDS EcolC_2342 NC_010468.1 2582282 2583031 D PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sdy:SDY_1361 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 2582282..2583031 Escherichia coli ATCC 8739 6067351 YP_001725305.1 CDS EcolC_2343 NC_010468.1 2583300 2583518 D KEGG: sbo:SBO_1781 osmotically inducible lipoprotein; lipoprotein 2583300..2583518 Escherichia coli ATCC 8739 6064765 YP_001725306.1 CDS EcolC_2344 NC_010468.1 2583644 2583970 R involved in start site selection during the initiation of translation; translation initiation factor Sui1 complement(2583644..2583970) Escherichia coli ATCC 8739 6065732 YP_001725307.1 CDS EcolC_2345 NC_010468.1 2583970 2584707 R type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(2583970..2584707) Escherichia coli ATCC 8739 6066877 YP_001725308.1 CDS EcolC_2346 NC_010468.1 2584900 2586069 R PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ssn:SSON_1860 putative heat shock protein; hypothetical protein complement(2584900..2586069) Escherichia coli ATCC 8739 6065641 YP_001725309.1 CDS EcolC_2347 NC_010468.1 2586076 2586384 R PFAM: protein of unknown function DUF1049; KEGG: sbo:SBO_1785 hypothetical protein; hypothetical protein complement(2586076..2586384) Escherichia coli ATCC 8739 6066278 YP_001725310.1 CDS EcolC_2348 NC_010468.1 2586533 2587297 R PFAM: phosphoesterase PA-phosphatase related; KEGG: sdy:SDY_1354 non-essential phosphatidylglycerophosphate phosphatase, membrane bound; phosphatidylglycerophosphatase B complement(2586533..2587297) Escherichia coli ATCC 8739 6067009 YP_001725311.1 CDS ribA NC_010468.1 2587467 2588057 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 2587467..2588057 Escherichia coli ATCC 8739 6067261 YP_001725312.1 CDS EcolC_2350 NC_010468.1 2588121 2590796 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(2588121..2590796) Escherichia coli ATCC 8739 6065173 YP_001725313.1 CDS EcolC_2351 NC_010468.1 2591169 2591336 R KEGG: ssn:SSON_1865 hypothetical protein; hypothetical protein complement(2591169..2591336) Escherichia coli ATCC 8739 6067143 YP_001725314.1 CDS EcolC_2352 NC_010468.1 2591339 2591467 R KEGG: sdy:SDY_1348 hypothetical protein; hypothetical protein complement(2591339..2591467) Escherichia coli ATCC 8739 6066683 YP_001725315.1 CDS cysB NC_010468.1 2591798 2592772 R LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB complement(2591798..2592772) Escherichia coli ATCC 8739 6065867 YP_001725316.1 CDS EcolC_2354 NC_010468.1 2592982 2595579 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(2592982..2595579) Escherichia coli ATCC 8739 6065617 YP_001725317.1 CDS EcolC_2355 NC_010468.1 2595959 2596210 D KEGG: sdy:SDY_1343 hypothetical protein; hypothetical protein 2595959..2596210 Escherichia coli ATCC 8739 6066833 YP_001725318.1 CDS EcolC_2356 NC_010468.1 2596246 2597295 R SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease complement(2596246..2597295) Escherichia coli ATCC 8739 6064794 YP_001725319.1 CDS EcolC_2357 NC_010468.1 2597515 2598273 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sdy:SDY_1341 putative oxidoreductase; short chain dehydrogenase 2597515..2598273 Escherichia coli ATCC 8739 6066231 YP_001725320.1 CDS EcolC_2358 NC_010468.1 2598270 2598860 D catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 2598270..2598860 Escherichia coli ATCC 8739 6065609 YP_001725321.1 CDS EcolC_2359 NC_010468.1 2598900 2599775 R catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B complement(2598900..2599775) Escherichia coli ATCC 8739 6065390 YP_001725322.1 CDS EcolC_2360 NC_010468.1 2599986 2601881 R KEGG: sbo:SBO_1798 hypothetical protein; hypothetical protein complement(2599986..2601881) Escherichia coli ATCC 8739 6064955 YP_001725323.1 CDS EcolC_2361 NC_010468.1 2601909 2602529 R TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: sbo:SBO_1799 hypothetical protein; hypothetical protein complement(2601909..2602529) Escherichia coli ATCC 8739 6065876 YP_001725324.1 CDS EcolC_2362 NC_010468.1 2602526 2603407 R PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfx:S1354 putative enzyme; phosphotransferase domain-containing protein complement(2602526..2603407) Escherichia coli ATCC 8739 6065135 YP_001725325.1 CDS EcolC_2363 NC_010468.1 2603681 2605243 D with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 2603681..2605243 Escherichia coli ATCC 8739 6065139 YP_001725326.1 CDS EcolC_2364 NC_010468.1 2605243 2606838 D bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 2605243..2606838 Escherichia coli ATCC 8739 6064879 YP_001725327.1 CDS EcolC_2365 NC_010468.1 2606842 2608200 D monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 2606842..2608200 Escherichia coli ATCC 8739 6066108 YP_001725328.1 CDS EcolC_2366 NC_010468.1 2608212 2609405 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2608212..2609405 Escherichia coli ATCC 8739 6065466 YP_001725329.1 CDS trpA NC_010468.1 2609405 2610211 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2609405..2610211 Escherichia coli ATCC 8739 6066005 YP_001725330.1 CDS EcolC_2368 NC_010468.1 2610592 2610771 D KEGG: sfv:SFV_1273 hypothetical protein; hypothetical protein 2610592..2610771 Escherichia coli ATCC 8739 6066994 YP_001725331.1 CDS EcolC_2369 NC_010468.1 2610857 2611357 D PFAM: protein of unknown function DUF892; KEGG: sfv:SFV_1272 putative structural proteins; hypothetical protein 2610857..2611357 Escherichia coli ATCC 8739 6067029 YP_001725332.1 CDS EcolC_2370 NC_010468.1 2611403 2611909 D PFAM: protein of unknown function DUF892; KEGG: sfv:SFV_1271 hypothetical protein; hypothetical protein 2611403..2611909 Escherichia coli ATCC 8739 6066632 YP_001725333.1 CDS EcolC_2371 NC_010468.1 2611969 2612607 R receptor for colicin S4; outer membrane protein W complement(2611969..2612607) Escherichia coli ATCC 8739 6065206 YP_001725334.1 CDS EcolC_2372 NC_010468.1 2612964 2613707 D PFAM: protein of unknown function UPF0259; KEGG: ssn:SSON_1911 hypothetical protein; hypothetical protein 2612964..2613707 Escherichia coli ATCC 8739 6067570 YP_001725335.1 CDS EcolC_2373 NC_010468.1 2613737 2614276 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 2613737..2614276 Escherichia coli ATCC 8739 6064963 YP_001725336.1 CDS EcolC_2374 NC_010468.1 2614381 2614779 D YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 2614381..2614779 Escherichia coli ATCC 8739 6064911 YP_001725337.1 CDS EcolC_2375 NC_010468.1 2614819 2615553 R membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter complement(2614819..2615553) Escherichia coli ATCC 8739 6066248 YP_001725338.1 CDS EcolC_2376 NC_010468.1 2615762 2616058 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 2615762..2616058 Escherichia coli ATCC 8739 6066694 YP_001725339.1 CDS EcolC_2377 NC_010468.1 2616358 2617611 D PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: sbo:SBO_1817 putative potassium channel protein; voltage-gated potassium channel 2616358..2617611 Escherichia coli ATCC 8739 6067152 YP_001725340.1 CDS EcolC_2378 NC_010468.1 2617666 2617839 R KEGG: cko:CKO_01327 hypothetical protein; hypothetical protein complement(2617666..2617839) Escherichia coli ATCC 8739 6065527 YP_001725341.1 CDS cls NC_010468.1 2617982 2619442 D catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 2617982..2619442 Escherichia coli ATCC 8739 6067575 YP_001725342.1 CDS EcolC_2380 NC_010468.1 2619477 2619806 D highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 2619477..2619806 Escherichia coli ATCC 8739 6064764 YP_001725343.1 CDS EcolC_2381 NC_010468.1 2619859 2620863 R KEGG: sfv:SFV_1259 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide/dipeptide ABC transporter ATPase complement(2619859..2620863) Escherichia coli ATCC 8739 6067523 YP_001725344.1 CDS oppD NC_010468.1 2620860 2621873 R KEGG: sfv:SFV_1258 ATP-binding protein of oligopeptide ABC transport system; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; oligopeptide transporter ATP-binding protein complement(2620860..2621873) Escherichia coli ATCC 8739 6065869 YP_001725345.1 CDS EcolC_2383 NC_010468.1 2621885 2622793 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ssn:SSON_1935 oligopeptide transport permease protein-like protein; binding-protein-dependent transport system inner membrane protein complement(2621885..2622793) Escherichia coli ATCC 8739 6064793 YP_001725346.1 CDS oppB NC_010468.1 2622808 2623728 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_1823 oligopeptide transport permease protein; oligopeptide transporter permease complement(2622808..2623728) Escherichia coli ATCC 8739 6066603 YP_001725347.1 CDS EcolC_2385 NC_010468.1 2623814 2625490 R PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1824 oligopeptide transport periplasmic binding protein; extracellular solute-binding protein complement(2623814..2625490) Escherichia coli ATCC 8739 6067119 YP_001725348.1 CDS EcolC_2386 NC_010468.1 2626183 2626830 R PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ssn:SSON_1938 putative channel protein; hypothetical protein complement(2626183..2626830) Escherichia coli ATCC 8739 6067583 YP_001725349.1 CDS EcolC_2387 NC_010468.1 2627307 2629982 D PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: sdy:SDY_1295 CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase/pyruvate-formate-lyase deactivase; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2627307..2629982 Escherichia coli ATCC 8739 6067039 YP_001725350.1 CDS EcolC_2389 NC_010468.1 2631284 2631901 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(2631284..2631901) Escherichia coli ATCC 8739 6065970 YP_001725351.1 CDS EcolC_2390 NC_010468.1 2632506 2632919 D PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sdy:SDY_1289 DNA-binding protein HLP-II; global DNA-binding transcriptional dual regulator H-NS 2632506..2632919 Escherichia coli ATCC 8739 6066062 YP_001725352.1 CDS EcolC_2391 NC_010468.1 2633063 2633971 R together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU complement(2633063..2633971) Escherichia coli ATCC 8739 6067481 YP_001725353.1 CDS EcolC_2392 NC_010468.1 2634173 2635186 R PFAM: response regulator receiver; KEGG: sdy:SDY_1287 Hnr protein; response regulator of RpoS complement(2634173..2635186) Escherichia coli ATCC 8739 6066321 YP_001725354.1 CDS EcolC_2393 NC_010468.1 2635278 2636222 R PFAM: Patatin; KEGG: ssn:SSON_1945 hypothetical protein; hypothetical protein complement(2635278..2636222) Escherichia coli ATCC 8739 6066484 YP_001725355.1 CDS EcolC_2394 NC_010468.1 2636296 2636754 D PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1836 hypothetical protein; hypothetical protein 2636296..2636754 Escherichia coli ATCC 8739 6066430 YP_001725356.1 CDS purU NC_010468.1 2636804 2637646 D produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 2636804..2637646 Escherichia coli ATCC 8739 6065755 YP_001725357.1 CDS EcolC_2396 NC_010468.1 2639081 2639758 R KEGG: ssn:SSON_1949 nitrate reductase 1, cytochrome b(NR), gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit; respiratory nitrate reductase subunit gamma complement(2639081..2639758) Escherichia coli ATCC 8739 6064342 YP_001725358.1 CDS EcolC_2397 NC_010468.1 2639758 2640468 R TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: ssn:SSON_1950 nitrate reductase 1, delta subunit, assembly function; nitrate reductase molybdenum cofactor assembly chaperone complement(2639758..2640468) Escherichia coli ATCC 8739 6066825 YP_001725359.1 CDS EcolC_2398 NC_010468.1 2640465 2642003 R TIGRFAM: nitrate reductase, beta subunit; KEGG: sbo:SBO_1841 nitrate reductase 1 beta subunit; nitrate reductase subunit beta complement(2640465..2642003) Escherichia coli ATCC 8739 6064341 YP_001725360.1 CDS EcolC_2399 NC_010468.1 2642000 2645743 R TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1240 nitrate reductase 1, alpha subunit; nitrate reductase subunit alpha complement(2642000..2645743) Escherichia coli ATCC 8739 6066859 YP_001725361.1 CDS EcolC_2400 NC_010468.1 2646259 2647650 R TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1843 nitrite extrusion protein; nitrite transporter complement(2646259..2647650) Escherichia coli ATCC 8739 6064484 YP_001725362.1 CDS EcolC_2401 NC_010468.1 2647989 2649785 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sfv:SFV_1238 nitrate/nitrate sensor, histidine protein kinase; nitrate/nitrite sensor protein NarX 2647989..2649785 Escherichia coli ATCC 8739 6066824 YP_001725363.1 CDS EcolC_2402 NC_010468.1 2649778 2650428 D two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 2649778..2650428 Escherichia coli ATCC 8739 6066788 YP_001725364.1 CDS EcolC_2403 NC_010468.1 2650429 2651859 R KEGG: ssn:SSON_1957 putative factor; hypothetical protein complement(2650429..2651859) Escherichia coli ATCC 8739 6068594 YP_001725365.1 CDS EcolC_2404 NC_010468.1 2652009 2652362 D PFAM: DsrE family protein; KEGG: sdy:SDY_1271 hypothetical protein; DsrE family protein 2652009..2652362 Escherichia coli ATCC 8739 6066709 YP_001725366.1 CDS EcolC_2405 NC_010468.1 2652406 2653122 R PFAM: ChaC family protein; KEGG: sbo:SBO_1848 cation transport regulator; ChaC family protein complement(2652406..2653122) Escherichia coli ATCC 8739 6066757 YP_001725367.1 CDS chaB NC_010468.1 2653259 2653489 R in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator complement(2653259..2653489) Escherichia coli ATCC 8739 6066678 YP_001725368.1 CDS EcolC_2407 NC_010468.1 2653759 2654859 D TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ssn:SSON_1961 sodium-calcium/proton antiporter; calcium/sodium:proton antiporter 2653759..2654859 Escherichia coli ATCC 8739 6066646 YP_001725369.1 CDS EcolC_2408 NC_010468.1 2655237 2655371 D KEGG: sfv:SFV_1231 hypothetical protein; hypothetical protein 2655237..2655371 Escherichia coli ATCC 8739 6068705 YP_001725370.1 CDS EcolC_2409 NC_010468.1 2655772 2655906 D KEGG: sbo:SBO_1851 hypothetical protein; hypothetical protein 2655772..2655906 Escherichia coli ATCC 8739 6064532 YP_001725371.1 CDS EcolC_2410 NC_010468.1 2656307 2656441 D KEGG: sbo:SBO_1851 hypothetical protein; hypothetical protein 2656307..2656441 Escherichia coli ATCC 8739 6066635 YP_001725372.1 CDS EcolC_2411 NC_010468.1 2656588 2657442 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(2656588..2657442) Escherichia coli ATCC 8739 6066544 YP_001725373.1 CDS EcolC_2412 NC_010468.1 2657478 2658287 R KEGG: sfv:SFV_1228 hypothetical protein; putative transcriptional regulator complement(2657478..2658287) Escherichia coli ATCC 8739 6066443 YP_001725374.1 CDS EcolC_2413 NC_010468.1 2658291 2658683 R PFAM: Invasion gene expression up-regulator SirB; KEGG: sdy:SDY_1262 hypothetical protein; putative transcriptional regulator complement(2658291..2658683) Escherichia coli ATCC 8739 6066505 YP_001725375.1 CDS EcolC_2414 NC_010468.1 2658680 2659513 R HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2658680..2659513) Escherichia coli ATCC 8739 6066435 YP_001725376.1 CDS prfA NC_010468.1 2659513 2660595 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(2659513..2660595) Escherichia coli ATCC 8739 6066487 YP_001725377.1 CDS hemA NC_010468.1 2660637 2661893 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(2660637..2661893) Escherichia coli ATCC 8739 6068570 YP_001725378.1 CDS lolB NC_010468.1 2662107 2662730 D Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 2662107..2662730 Escherichia coli ATCC 8739 6066427 YP_001725379.1 CDS ipk NC_010468.1 2662730 2663581 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2662730..2663581 Escherichia coli ATCC 8739 6066426 YP_001725380.1 CDS EcolC_2419 NC_010468.1 2663732 2664679 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2663732..2664679 Escherichia coli ATCC 8739 6066395 YP_001725381.1 CDS EcolC_2420 NC_010468.1 2664831 2666483 D putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM 2664831..2666483 Escherichia coli ATCC 8739 6066168 YP_001725382.1 CDS EcolC_2421 NC_010468.1 2666538 2666816 R YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein complement(2666538..2666816) Escherichia coli ATCC 8739 6066172 YP_001725383.1 CDS EcolC_2422 NC_010468.1 2667094 2667678 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2667094..2667678 Escherichia coli ATCC 8739 6067084 YP_001725384.1 CDS EcolC_2423 NC_010468.1 2667795 2668886 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2667795..2668886 Escherichia coli ATCC 8739 6068471 YP_001725385.1 CDS EcolC_2424 NC_010468.1 2669655 2672522 D TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfx:S1289 putative adhesion and penetration protein; outer membrane autotransporter 2669655..2672522 Escherichia coli ATCC 8739 6068472 YP_001725386.1 CDS EcolC_2425 NC_010468.1 2672622 2674541 R Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR complement(2672622..2674541) Escherichia coli ATCC 8739 6066304 YP_001725387.1 CDS EcolC_2426 NC_010468.1 2674769 2675839 D with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 2674769..2675839 Escherichia coli ATCC 8739 6066264 YP_001725388.1 CDS EcolC_2427 NC_010468.1 2675850 2676482 D with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 2675850..2676482 Escherichia coli ATCC 8739 6068597 YP_001725389.1 CDS EcolC_2428 NC_010468.1 2676493 2677911 D phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM 2676493..2677911 Escherichia coli ATCC 8739 6064460 YP_001725390.1 CDS treA NC_010468.1 2678231 2679928 D periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 2678231..2679928 Escherichia coli ATCC 8739 6066275 YP_001725391.1 CDS EcolC_2430 NC_010468.1 2680625 2680879 R PFAM: Transglycosylase-associated protein; KEGG: sdy:SDY_1234 hypothetical protein; transglycosylase-associated protein complement(2680625..2680879) Escherichia coli ATCC 8739 6066281 YP_001725392.1 CDS EcolC_2431 NC_010468.1 2681080 2681814 D PFAM: type IV pilus assembly PilZ; YcgR family protein; KEGG: sbo:SBO_1878 hypothetical protein; YcgR family protein 2681080..2681814 Escherichia coli ATCC 8739 6066367 YP_001725393.1 CDS EcolC_2432 NC_010468.1 2681816 2682427 R PFAM: Lytic transglycosylase catalytic; KEGG: ssn:SSON_1184 murein transglycosylase E; lytic transglycosylase complement(2681816..2682427) Escherichia coli ATCC 8739 6065262 YP_001725394.1 CDS ldcA NC_010468.1 2682527 2683441 D catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 2682527..2683441 Escherichia coli ATCC 8739 6064345 YP_001725395.1 CDS EcolC_2434 NC_010468.1 2683536 2685272 D the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 2683536..2685272 Escherichia coli ATCC 8739 6068426 YP_001725396.1 CDS dadX NC_010468.1 2685658 2686728 R catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase complement(2685658..2686728) Escherichia coli ATCC 8739 6066318 YP_001725397.1 CDS EcolC_2436 NC_010468.1 2686738 2688036 R catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit complement(2686738..2688036) Escherichia coli ATCC 8739 6065854 YP_001725398.1 CDS EcolC_2437 NC_010468.1 2688366 2689898 D PFAM: SpoVR family protein; KEGG: ssn:SSON_1180 putative sporulation protein; SpoVR family protein 2688366..2689898 Escherichia coli ATCC 8739 6068490 YP_001725399.1 CDS EcolC_2438 NC_010468.1 2689950 2690669 R Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator complement(2689950..2690669) Escherichia coli ATCC 8739 6065842 YP_001725400.1 CDS nhaB NC_010468.1 2690890 2692431 D involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 2690890..2692431 Escherichia coli ATCC 8739 6068476 YP_001725401.1 CDS EcolC_2440 NC_010468.1 2692577 2693107 D disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 2692577..2693107 Escherichia coli ATCC 8739 6066030 YP_001725402.1 CDS umuC NC_010468.1 2693153 2694421 R binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC complement(2693153..2694421) Escherichia coli ATCC 8739 6066095 YP_001725403.1 CDS EcolC_2442 NC_010468.1 2694421 2694840 R binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD complement(2694421..2694840) Escherichia coli ATCC 8739 6066101 YP_001725404.1 CDS EcolC_2444 NC_010468.1 2696320 2696766 R PFAM: protein of unknown function UPF0153; KEGG: sfv:SFV_1188 hypothetical protein; hypothetical protein complement(2696320..2696766) Escherichia coli ATCC 8739 6068292 YP_001725405.1 CDS EcolC_2445 NC_010468.1 2696858 2697517 R PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sbo:SBO_1166 putative isomerase; hypothetical protein complement(2696858..2697517) Escherichia coli ATCC 8739 6068409 YP_001725406.1 CDS EcolC_2446 NC_010468.1 2697589 2697882 R PFAM: protein of unknown function DUF709; KEGG: sbo:SBO_1165 hypothetical protein; hypothetical protein complement(2697589..2697882) Escherichia coli ATCC 8739 6068373 YP_001725407.1 CDS EcolC_2447 NC_010468.1 2698124 2698525 D PFAM: peptidase domain protein; KEGG: sdy:SDY_1210 hypothetical protein; peptidase domain-containing protein 2698124..2698525 Escherichia coli ATCC 8739 6065973 YP_001725408.1 CDS EcolC_2448 NC_010468.1 2698628 2698996 R PFAM: Fels-1 Propage domain protein; KEGG: ssn:SSON_1166 hypothetical protein; Fels-1 Propage domain-containing protein complement(2698628..2698996) Escherichia coli ATCC 8739 6065993 YP_001725409.1 CDS minC NC_010468.1 2699516 2700211 D blocks the formation of polar Z-ring septums; septum formation inhibitor 2699516..2700211 Escherichia coli ATCC 8739 6066014 YP_001725410.1 CDS EcolC_2450 NC_010468.1 2700235 2701047 D ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 2700235..2701047 Escherichia coli ATCC 8739 6068258 YP_001725411.1 CDS minE NC_010468.1 2701051 2701317 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 2701051..2701317 Escherichia coli ATCC 8739 6065873 YP_001725412.1 CDS EcolC_2453 NC_010468.1 2702668 2702922 D KEGG: sbo:SBO_1897 hypothetical protein; hypothetical protein 2702668..2702922 Escherichia coli ATCC 8739 6068723 YP_001725413.1 CDS EcolC_2454 NC_010468.1 2702973 2703670 D PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein join(2702973..2703227,2703227..2703670) Escherichia coli ATCC 8739 6067055 YP_001725414.1 CDS EcolC_2455 NC_010468.1 2703739 2704068 D KEGG: ssn:SSON_1161 hypothetical protein; hypothetical protein 2703739..2704068 Escherichia coli ATCC 8739 6067054 YP_001725415.1 CDS EcolC_2457 NC_010468.1 2707171 2707425 R hypothetical protein complement(2707171..2707425) Escherichia coli ATCC 8739 6067043 YP_001725416.1 CDS EcolC_2458 NC_010468.1 2707521 2709086 R PFAM: EAL domain protein; KEGG: sfx:S1241 hypothetical protein; diguanylate phosphodiesterase complement(2707521..2709086) Escherichia coli ATCC 8739 6067030 YP_001725417.1 CDS EcolC_2459 NC_010468.1 2709376 2709624 R hypothetical protein complement(2709376..2709624) Escherichia coli ATCC 8739 6067027 YP_001725418.1 CDS EcolC_2460 NC_010468.1 2709737 2710003 R KEGG: ent:Ent638_1754 hypothetical protein; hypothetical protein complement(2709737..2710003) Escherichia coli ATCC 8739 6067023 YP_001725419.1 CDS EcolC_2461 NC_010468.1 2710032 2710304 R hypothetical protein complement(2710032..2710304) Escherichia coli ATCC 8739 6067017 YP_001725420.1 CDS EcolC_2462 NC_010468.1 2710347 2710583 R KEGG: ent:Ent638_1756 hypothetical protein; hypothetical protein complement(2710347..2710583) Escherichia coli ATCC 8739 6067013 YP_001725421.1 CDS EcolC_2463 NC_010468.1 2710897 2712108 D PFAM: EAL domain protein; BLUF domain protein; KEGG: kpn:KPN_00782 hypothetical protein; diguanylate phosphodiesterase 2710897..2712108 Escherichia coli ATCC 8739 6067005 YP_001725422.1 CDS EcolC_2464 NC_010468.1 2712313 2713044 D PFAM: regulatory protein MerR; KEGG: ssn:SSON_1157 putative transcriptional regulator; MerR family transcriptional regulator 2712313..2713044 Escherichia coli ATCC 8739 6068672 YP_001725423.1 CDS EcolC_2465 NC_010468.1 2713265 2713669 D PFAM: protein of unknown function DUF1398; KEGG: ssn:SSON_1156 hypothetical protein; hypothetical protein 2713265..2713669 Escherichia coli ATCC 8739 6064587 YP_001725424.1 CDS EcolC_2466 NC_010468.1 2714369 2714692 D KEGG: sdy:SDY_2015 hypothetical protein; hypothetical protein 2714369..2714692 Escherichia coli ATCC 8739 6067425 YP_001725425.1 CDS EcolC_2467 NC_010468.1 2714795 2716045 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(2714795..2716045) Escherichia coli ATCC 8739 6065921 YP_001725426.1 CDS EcolC_2468 NC_010468.1 2716217 2716870 D catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 2716217..2716870 Escherichia coli ATCC 8739 6067650 YP_001725427.1 CDS EcolC_2469 NC_010468.1 2716880 2717341 D PFAM: NUDIX hydrolase; KEGG: sdy:SDY_2018 putative phosphohydrolase; NUDIX hydrolase 2716880..2717341 Escherichia coli ATCC 8739 6065026 YP_001725428.1 CDS mnmA NC_010468.1 2717395 2718501 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2717395..2718501 Escherichia coli ATCC 8739 6064998 YP_001725429.1 CDS EcolC_2471 NC_010468.1 2718537 2719178 D HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 2718537..2719178 Escherichia coli ATCC 8739 6064876 YP_001725430.1 CDS EcolC_2472 NC_010468.1 2719182 2720552 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 2719182..2720552 Escherichia coli ATCC 8739 6064721 YP_001725431.1 CDS EcolC_2473 NC_010468.1 2720721 2721392 D response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 2720721..2721392 Escherichia coli ATCC 8739 6067624 YP_001725432.1 CDS EcolC_2474 NC_010468.1 2721392 2722852 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: sbo:SBO_1910 sensor protein PhoQ; sensor protein PhoQ 2721392..2722852 Escherichia coli ATCC 8739 6067606 YP_001725433.1 CDS EcolC_2475 NC_010468.1 2722928 2724049 D PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: sbo:SBO_1911 hypothetical protein; cupin 4 family protein 2722928..2724049 Escherichia coli ATCC 8739 6067384 YP_001725434.1 CDS EcolC_2476 NC_010468.1 2724098 2725324 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(2724098..2725324) Escherichia coli ATCC 8739 6066875 YP_001725435.1 CDS potA NC_010468.1 2725574 2726710 D functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 2725574..2726710 Escherichia coli ATCC 8739 6066749 YP_001725436.1 CDS potB NC_010468.1 2726694 2727551 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 2726694..2727551 Escherichia coli ATCC 8739 6066740 YP_001725437.1 CDS potC NC_010468.1 2727548 2728342 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 2727548..2728342 Escherichia coli ATCC 8739 6066522 YP_001725438.1 CDS potD NC_010468.1 2728339 2729385 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 2728339..2729385 Escherichia coli ATCC 8739 6066170 YP_001725439.1 CDS EcolC_2481 NC_010468.1 2729522 2730361 R Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase complement(2729522..2730361) Escherichia coli ATCC 8739 6065722 YP_001725440.1 CDS EcolC_2482 NC_010468.1 2730377 2731288 R catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase complement(2730377..2731288) Escherichia coli ATCC 8739 6065563 YP_001725441.1 CDS EcolC_2483 NC_010468.1 2731317 2732555 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE complement(2731317..2732555) Escherichia coli ATCC 8739 6065438 YP_001725442.1 CDS lolD NC_010468.1 2732561 2733262 R outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit complement(2732561..2733262) Escherichia coli ATCC 8739 6065274 YP_001725443.1 CDS EcolC_2485 NC_010468.1 2733255 2734454 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC complement(2733255..2734454) Escherichia coli ATCC 8739 6065254 YP_001725444.1 CDS EcolC_2486 NC_010468.1 2734716 2735789 D PFAM: acyltransferase 3; KEGG: ssn:SSON_1135 hypothetical protein; acyltransferase 3 2734716..2735789 Escherichia coli ATCC 8739 6065817 YP_001725445.1 CDS EcolC_2487 NC_010468.1 2735869 2739363 D KEGG: sfv:SFV_1134 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; transcription-repair coupling factor 2735869..2739363 Escherichia coli ATCC 8739 6065208 YP_001725446.1 CDS EcolC_2488 NC_010468.1 2739510 2740469 D PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2037 hypothetical protein; ErfK/YbiS/YcfS/YnhG family protein 2739510..2740469 Escherichia coli ATCC 8739 6065172 YP_001725447.1 CDS EcolC_2489 NC_010468.1 2740552 2740809 R PFAM: protein of unknown function DUF1471; KEGG: sdy:SDY_2038 hypothetical protein; hypothetical protein complement(2740552..2740809) Escherichia coli ATCC 8739 6064894 YP_001725448.1 CDS EcolC_2490 NC_010468.1 2741050 2741682 D PFAM: regulatory protein TetR; KEGG: sdy:SDY_2039 hypothetical protein; TetR family transcriptional regulator 2741050..2741682 Escherichia coli ATCC 8739 6064862 YP_001725449.1 CDS EcolC_2491 NC_010468.1 2741744 2742283 R PFAM: 17 kDa surface antigen; KEGG: sdy:SDY_2040 hypothetical protein; hypothetical protein complement(2741744..2742283) Escherichia coli ATCC 8739 6064754 YP_001725450.1 CDS EcolC_2492 NC_010468.1 2742510 2743814 R PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sfx:S1193 respiratory NADH dehydrogenase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(2742510..2743814) Escherichia coli ATCC 8739 6066509 YP_001725451.1 CDS EcolC_2493 NC_010468.1 2744222 2744764 R PFAM: protein of unknown function UPF0227; KEGG: sdy:SDY_2042 hypothetical protein; hypothetical protein complement(2744222..2744764) Escherichia coli ATCC 8739 6065666 YP_001725452.1 CDS EcolC_2494 NC_010468.1 2744787 2745812 R hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(2744787..2745812) Escherichia coli ATCC 8739 6067647 YP_001725453.1 CDS thiK NC_010468.1 2745823 2746647 R catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase complement(2745823..2746647) Escherichia coli ATCC 8739 6067178 YP_001725454.1 CDS EcolC_2496 NC_010468.1 2746628 2747269 R TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: sdy:SDY_2045 hypothetical protein; membrane lipoprotein lipid attachment site complement(2746628..2747269) Escherichia coli ATCC 8739 6067150 YP_001725455.1 CDS EcolC_2497 NC_010468.1 2747283 2747660 R PFAM: protein of unknown function DUF1425; KEGG: sdy:SDY_2046 hypothetical protein; hypothetical protein complement(2747283..2747660) Escherichia coli ATCC 8739 6066739 YP_001725456.1 CDS EcolC_2498 NC_010468.1 2747663 2748022 R PFAM: histidine triad (HIT) protein; KEGG: sdy:SDY_2047 hypothetical protein; purine nucleoside phosphoramidase complement(2747663..2748022) Escherichia coli ATCC 8739 6065914 YP_001725457.1 CDS EcolC_2499 NC_010468.1 2748356 2750545 D TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sdy:SDY_2048 outer membrane receptor for ferric iron uptake; ferric-rhodotorulic acid outer membrane transporter 2748356..2750545 Escherichia coli ATCC 8739 6065845 YP_001725458.1 CDS EcolC_2500 NC_010468.1 2750605 2752038 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC complement(2750605..2752038) Escherichia coli ATCC 8739 6066847 YP_001725459.1 CDS EcolC_2501 NC_010468.1 2752333 2753130 R TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: sdy:SDY_2050 hypothetical protein; putative metallodependent hydrolase complement(2752333..2753130) Escherichia coli ATCC 8739 6067376 YP_001725460.1 CDS EcolC_2502 NC_010468.1 2753141 2754145 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(2753141..2754145) Escherichia coli ATCC 8739 6065974 YP_001725461.1 CDS tmk NC_010468.1 2754142 2754783 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(2754142..2754783) Escherichia coli ATCC 8739 6066038 YP_001725462.1 CDS EcolC_2504 NC_010468.1 2754773 2755795 R PFAM: aminodeoxychorismate lyase; KEGG: sbo:SBO_1966 putative thymidylate kinase; hypothetical protein complement(2754773..2755795) Escherichia coli ATCC 8739 6066341 YP_001725463.1 CDS EcolC_2505 NC_010468.1 2755798 2756607 R catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase complement(2755798..2756607) Escherichia coli ATCC 8739 6065127 YP_001725464.1 CDS EcolC_2506 NC_010468.1 2756727 2757968 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(2756727..2757968) Escherichia coli ATCC 8739 6066138 YP_001725465.1 CDS acpP NC_010468.1 2758056 2758292 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(2758056..2758292) Escherichia coli ATCC 8739 6066350 YP_001725466.1 CDS fabG NC_010468.1 2758503 2759237 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(2758503..2759237) Escherichia coli ATCC 8739 6066387 YP_001725467.1 CDS EcolC_2509 NC_010468.1 2759250 2760179 R TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: sfv:SFV_1112 malonyl-CoA-[acyl-carrier-protein] transacylase; malonyl CoA-acyl carrier protein transacylase complement(2759250..2760179) Escherichia coli ATCC 8739 6066647 YP_001725468.1 CDS EcolC_2510 NC_010468.1 2760195 2761148 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(2760195..2761148) Escherichia coli ATCC 8739 6066849 YP_001725469.1 CDS EcolC_2511 NC_010468.1 2761216 2762286 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(2761216..2762286) Escherichia coli ATCC 8739 6066778 YP_001725470.1 CDS rpmF NC_010468.1 2762367 2762540 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(2762367..2762540) Escherichia coli ATCC 8739 6066818 YP_001725471.1 CDS EcolC_2513 NC_010468.1 2762592 2763113 R PFAM: protein of unknown function DUF177; KEGG: sbo:SBO_1975 hypothetical protein; hypothetical protein complement(2762592..2763113) Escherichia coli ATCC 8739 6066890 YP_001725472.1 CDS EcolC_2514 NC_010468.1 2763273 2763896 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 2763273..2763896 Escherichia coli ATCC 8739 6066880 YP_001725473.1 CDS EcolC_2515 NC_010468.1 2764008 2764967 R catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(2764008..2764967) Escherichia coli ATCC 8739 6067180 YP_001725474.1 CDS rne NC_010468.1 2765540 2768725 D bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 2765540..2768725 Escherichia coli ATCC 8739 6067377 YP_001725475.1 CDS flgL NC_010468.1 2768922 2769875 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL complement(2768922..2769875) Escherichia coli ATCC 8739 6067369 YP_001725476.1 CDS flgK NC_010468.1 2769887 2771530 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(2769887..2771530) Escherichia coli ATCC 8739 6067378 YP_001725477.1 CDS flgJ NC_010468.1 2771596 2772537 R Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ complement(2771596..2772537) Escherichia coli ATCC 8739 6067379 YP_001725478.1 CDS flgI NC_010468.1 2772537 2773634 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(2772537..2773634) Escherichia coli ATCC 8739 6067381 YP_001725479.1 CDS flgH NC_010468.1 2773646 2774353 R part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein complement(2773646..2774353) Escherichia coli ATCC 8739 6067419 YP_001725480.1 CDS flgG NC_010468.1 2774397 2775179 R makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG complement(2774397..2775179) Escherichia coli ATCC 8739 6067435 YP_001725481.1 CDS flgF NC_010468.1 2775351 2776106 R FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF complement(2775351..2776106) Escherichia coli ATCC 8739 6067421 YP_001725482.1 CDS flgE NC_010468.1 2776126 2777334 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(2776126..2777334) Escherichia coli ATCC 8739 6067440 YP_001725483.1 CDS flgD NC_010468.1 2777359 2778054 R acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein complement(2777359..2778054) Escherichia coli ATCC 8739 6067473 YP_001725484.1 CDS flgC NC_010468.1 2778066 2778470 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(2778066..2778470) Escherichia coli ATCC 8739 6067228 YP_001725485.1 CDS flgB NC_010468.1 2778474 2778890 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(2778474..2778890) Escherichia coli ATCC 8739 6067476 YP_001725486.1 CDS flgA NC_010468.1 2779046 2779705 D required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 2779046..2779705 Escherichia coli ATCC 8739 6067483 YP_001725487.1 CDS EcolC_2529 NC_010468.1 2779781 2780074 D regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 2779781..2780074 Escherichia coli ATCC 8739 6067480 YP_001725488.1 CDS EcolC_2530 NC_010468.1 2780079 2780495 D PFAM: FlgN family protein; KEGG: ssn:SSON_1090 protein of flagellar biosynthesis; FlgN family protein 2780079..2780495 Escherichia coli ATCC 8739 6067489 YP_001725489.1 CDS EcolC_2531 NC_010468.1 2780535 2782070 R TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: sbo:SBO_1995 putative virulence factor; integral membrane protein MviN complement(2780535..2782070) Escherichia coli ATCC 8739 6067486 YP_001725490.1 CDS EcolC_2532 NC_010468.1 2782180 2783103 R PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: sdy:SDY_2084 putative virulence factor; oxidoreductase domain-containing protein complement(2782180..2783103) Escherichia coli ATCC 8739 6067514 YP_001725491.1 CDS EcolC_2533 NC_010468.1 2783105 2783752 R PFAM: protein of unknown function DUF480; KEGG: ssn:SSON_1087 hypothetical protein; hypothetical protein complement(2783105..2783752) Escherichia coli ATCC 8739 6067576 YP_001725492.1 CDS EcolC_2534 NC_010468.1 2783763 2784347 R PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_1998 RimJ; ribosomal-protein-S5-alanine N-acetyltransferase complement(2783763..2784347) Escherichia coli ATCC 8739 6067603 YP_001725493.1 CDS EcolC_2535 NC_010468.1 2784583 2785791 D Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 2784583..2785791 Escherichia coli ATCC 8739 6067582 YP_001725494.1 CDS EcolC_2536 NC_010468.1 2785855 2786502 D cofactor involved in the reduction of disulfides; glutaredoxin 2785855..2786502 Escherichia coli ATCC 8739 6067635 YP_001725495.1 CDS EcolC_2537 NC_010468.1 2786636 2787196 D PFAM: protein of unknown function DUF1439; KEGG: sbo:SBO_2001 hypothetical protein; hypothetical protein 2786636..2787196 Escherichia coli ATCC 8739 6067268 YP_001725496.1 CDS EcolC_2538 NC_010468.1 2787302 2788348 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 2787302..2788348 Escherichia coli ATCC 8739 6066465 YP_001725497.1 CDS EcolC_2539 NC_010468.1 2788422 2788667 D PFAM: DinI family protein; KEGG: ssn:SSON_1081 damage-inducible protein I; DNA damage-inducible protein I 2788422..2788667 Escherichia coli ATCC 8739 6066285 YP_001725498.1 CDS bssS NC_010468.1 2788957 2789211 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 2788957..2789211 Escherichia coli ATCC 8739 6064997 YP_001725499.1 CDS solA NC_010468.1 2789326 2790444 D catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 2789326..2790444 Escherichia coli ATCC 8739 6065286 YP_001725500.1 CDS EcolC_2542 NC_010468.1 2790492 2790605 D KEGG: sdy:SDY_2097 hypothetical protein; hypothetical protein 2790492..2790605 Escherichia coli ATCC 8739 6064931 YP_001725501.1 CDS EcolC_2543 NC_010468.1 2790866 2791432 D PFAM: cytochrome B561; KEGG: ssn:SSON_1077 putative cytochrome; cytochrome B561 2790866..2791432 Escherichia coli ATCC 8739 6066801 YP_001725502.1 CDS EcolC_2544 NC_010468.1 2791436 2792011 D PFAM: YceI family protein; KEGG: sbo:SBO_2008 hypothetical protein; hypothetical protein 2791436..2792011 Escherichia coli ATCC 8739 6065397 YP_001725503.1 CDS EcolC_2545 NC_010468.1 2792053 2793105 R PFAM: Rhodanese domain protein; KEGG: sfv:SFV_1078 hypothetical protein; hypothetical protein complement(2792053..2793105) Escherichia coli ATCC 8739 6066165 YP_001725504.1 CDS EcolC_2546 NC_010468.1 2793330 2794250 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 2793330..2794250 Escherichia coli ATCC 8739 6066529 YP_001725505.1 CDS EcolC_2547 NC_010468.1 2794422 2795648 D Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 2794422..2795648 Escherichia coli ATCC 8739 6066277 YP_001725506.1 CDS EcolC_2548 NC_010468.1 2795731 2796105 D KEGG: sdy:SDY_2299 acidic protein; hypothetical protein 2795731..2796105 Escherichia coli ATCC 8739 6066526 YP_001725507.1 CDS EcolC_2549 NC_010468.1 2796106 2796333 R PFAM: protein of unknown function DUF1375; KEGG: sdy:SDY_2300 hypothetical protein; hypothetical protein complement(2796106..2796333) Escherichia coli ATCC 8739 6066636 YP_001725508.1 CDS EcolC_2550 NC_010468.1 2796506 2799049 R necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH complement(2796506..2799049) Escherichia coli ATCC 8739 6067328 YP_001725509.1 CDS mdoG NC_010468.1 2799042 2800577 R involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G complement(2799042..2800577) Escherichia coli ATCC 8739 6067535 YP_001725510.1 CDS mdoC NC_010468.1 2800971 2802128 D required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 2800971..2802128 Escherichia coli ATCC 8739 6067447 YP_001725511.1 CDS EcolC_2553 NC_010468.1 2802136 2803566 R PFAM: phospholipase D/Transphosphatidylase; KEGG: sfx:S1116 putative synthase; phospholipase D/transphosphatidylase complement(2802136..2803566) Escherichia coli ATCC 8739 6067628 YP_001725512.1 CDS EcolC_2554 NC_010468.1 2803559 2804092 R PFAM: Appr-1-p processing domain protein; KEGG: sbo:SBO_2021 putative polyprotein; hypothetical protein complement(2803559..2804092) Escherichia coli ATCC 8739 6067555 YP_001725513.1 CDS EcolC_2555 NC_010468.1 2804187 2804498 R KEGG: ssn:SSON_1057 hypothetical protein; hypothetical protein complement(2804187..2804498) Escherichia coli ATCC 8739 6066894 YP_001725514.1 CDS csgC NC_010468.1 2804619 2804951 R involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein complement(2804619..2804951) Escherichia coli ATCC 8739 6066754 YP_001725515.1 CDS EcolC_2557 NC_010468.1 2805010 2805465 R KEGG: sbo:SBO_2026 CsgA; cryptic curlin major subunit complement(2805010..2805465) Escherichia coli ATCC 8739 6064645 YP_001725516.1 CDS EcolC_2558 NC_010468.1 2805506 2805961 R CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit complement(2805506..2805961) Escherichia coli ATCC 8739 6064775 YP_001725517.1 CDS EcolC_2559 NC_010468.1 2806716 2807366 D activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 2806716..2807366 Escherichia coli ATCC 8739 6064749 YP_001725518.1 CDS EcolC_2560 NC_010468.1 2807371 2807760 D chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 2807371..2807760 Escherichia coli ATCC 8739 6064753 YP_001725519.1 CDS EcolC_2561 NC_010468.1 2807785 2808201 D nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 2807785..2808201 Escherichia coli ATCC 8739 6064746 YP_001725520.1 CDS EcolC_2562 NC_010468.1 2808228 2809061 D PFAM: Curli production assembly/transport component CsgG; KEGG: ssn:SSON_1046 curli production assembly/transport component, 2nd curli operon; curli production assembly/transport component CsgG 2808228..2809061 Escherichia coli ATCC 8739 6064810 YP_001725521.1 CDS EcolC_2563 NC_010468.1 2809125 2809646 R PFAM: protein of unknown function DUF1097; KEGG: sbo:SBO_2032 hypothetical protein; hypothetical protein complement(2809125..2809646) Escherichia coli ATCC 8739 6066661 YP_001725522.1 CDS EcolC_2564 NC_010468.1 2809718 2810272 R PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfv:SFV_1046 putative oxidoreductase component; cytoplasmic chaperone TorD family protein complement(2809718..2810272) Escherichia coli ATCC 8739 6065707 YP_001725523.1 CDS EcolC_2565 NC_010468.1 2810296 2811033 R PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sbo:SBO_2034 hypothetical protein; putative hydrolase complement(2810296..2811033) Escherichia coli ATCC 8739 6065797 YP_001725524.1 CDS EcolC_2566 NC_010468.1 2811088 2812026 R PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1042 putative dehydrogenase; NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase complement(2811088..2812026) Escherichia coli ATCC 8739 6065906 YP_001725525.1 CDS EcolC_2567 NC_010468.1 2812902 2813888 R KEGG: sfv:SFV_1042 hypothetical protein; hypothetical protein complement(2812902..2813888) Escherichia coli ATCC 8739 6065163 YP_001725526.1 CDS EcolC_2568 NC_010468.1 2813885 2814208 R KEGG: sfv:SFV_1041 hypothetical protein; hypothetical protein complement(2813885..2814208) Escherichia coli ATCC 8739 6065047 YP_001725527.1 CDS EcolC_2569 NC_010468.1 2814294 2814593 D PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 2814294..2814593 Escherichia coli ATCC 8739 6065058 YP_001725528.1 CDS EcolC_2570 NC_010468.1 2814590 2815456 D PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 2814590..2815456 Escherichia coli ATCC 8739 6065037 YP_001725529.1 CDS EcolC_2571 NC_010468.1 2815497 2816855 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ssn:SSON_1377 hypothetical protein; diguanylate cyclase complement(2815497..2816855) Escherichia coli ATCC 8739 6065004 YP_001725530.1 CDS pgaA NC_010468.1 2817442 2819865 D outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 2817442..2819865 Escherichia coli ATCC 8739 6065019 YP_001725531.1 CDS pgaB NC_010468.1 2819874 2821892 D in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 2819874..2821892 Escherichia coli ATCC 8739 6064986 YP_001725532.1 CDS EcolC_2574 NC_010468.1 2821972 2823210 D predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2821972..2823210 Escherichia coli ATCC 8739 6065010 YP_001725533.1 CDS pgaD NC_010468.1 2823212 2823625 D in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; putative PGA biosynthesis protein 2823212..2823625 Escherichia coli ATCC 8739 6064957 YP_001725534.1 CDS EcolC_2576 NC_010468.1 2823675 2824739 R PFAM: PhoH family protein; KEGG: sbo:SBO_2038 PhoB-dependent, ATP-binding pho regulon component; hypothetical protein complement(2823675..2824739) Escherichia coli ATCC 8739 6064930 YP_001725535.1 CDS EcolC_2577 NC_010468.1 2825084 2826355 R TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbo:SBO_2039 hypothetical protein; Dyp-type peroxidase family protein complement(2825084..2826355) Escherichia coli ATCC 8739 6064360 YP_001725536.1 CDS EcolC_2578 NC_010468.1 2826361 2827488 R KEGG: ssn:SSON_1037 hypothetical protein; hypothetical protein complement(2826361..2827488) Escherichia coli ATCC 8739 6067275 YP_001725537.1 CDS EcolC_2579 NC_010468.1 2827546 2828376 R TIGRFAM: FTR1 family protein; PFAM: iron permease FTR1; KEGG: ssn:SSON_1036 high-affinity iron permease; FTR1 family protein complement(2827546..2828376) Escherichia coli ATCC 8739 6066602 YP_001725538.1 CDS EcolC_2580 NC_010468.1 2828918 2830426 R TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: sbo:SBO_2042 major sodium/proline symporter; sodium/proline symporter complement(2828918..2830426) Escherichia coli ATCC 8739 6067279 YP_001725539.1 CDS putA NC_010468.1 2830849 2834811 D proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 2830849..2834811 Escherichia coli ATCC 8739 6066504 YP_001725540.1 CDS EcolC_2582 NC_010468.1 2834851 2835489 R PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YcdC domain protein; KEGG: sfv:SFV_1025 putative tet operon regulator; TetR family transcriptional regulator complement(2834851..2835489) Escherichia coli ATCC 8739 6064884 YP_001725541.1 CDS EcolC_2583 NC_010468.1 2835778 2836869 D PFAM: luciferase family protein; KEGG: sfv:SFV_1024 hypothetical protein; luciferase family protein 2835778..2836869 Escherichia coli ATCC 8739 6065458 YP_001725542.1 CDS EcolC_2584 NC_010468.1 2836866 2837561 D PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1030 putative synthetase; isochorismatase hydrolase 2836866..2837561 Escherichia coli ATCC 8739 6064818 YP_001725543.1 CDS EcolC_2585 NC_010468.1 2837573 2837959 D PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_0985 hypothetical protein; endoribonuclease L-PSP 2837573..2837959 Escherichia coli ATCC 8739 6066796 YP_001725544.1 CDS EcolC_2586 NC_010468.1 2837967 2838767 D PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_1027 putative acetyltransferase; alpha/beta hydrolase fold protein 2837967..2838767 Escherichia coli ATCC 8739 6067530 YP_001725545.1 CDS EcolC_2587 NC_010468.1 2838777 2839367 D PFAM: nitroreductase; KEGG: sfv:SFV_1020 putative enzyme; hypothetical protein 2838777..2839367 Escherichia coli ATCC 8739 6066638 YP_001725546.1 CDS EcolC_2588 NC_010468.1 2839378 2839872 D PFAM: flavin reductase domain protein FMN-binding; KEGG: sfv:SFV_1019 hypothetical protein; flavin reductase domain-containing protein 2839378..2839872 Escherichia coli ATCC 8739 6067254 YP_001725547.1 CDS EcolC_2589 NC_010468.1 2839893 2841221 D TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_1024 putative transport protein; uracil-xanthine permease 2839893..2841221 Escherichia coli ATCC 8739 6067194 YP_001725548.1 CDS EcolC_2590 NC_010468.1 2841479 2841652 R KEGG: cko:CKO_02046 hypothetical protein; hypothetical protein complement(2841479..2841652) Escherichia coli ATCC 8739 6065635 YP_001725549.1 CDS EcolC_2591 NC_010468.1 2842025 2842621 D stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 2842025..2842621 Escherichia coli ATCC 8739 6067454 YP_001725550.1 CDS EcolC_2592 NC_010468.1 2842642 2842869 D KEGG: sdy:SDY_0979 hypothetical protein; hypothetical protein 2842642..2842869 Escherichia coli ATCC 8739 6065494 YP_001725551.1 CDS EcolC_2593 NC_010468.1 2843089 2844330 R PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 periplasmic glucose-1-phosphatase; glucose-1-phosphatase/inositol phosphatase complement(2843089..2844330) Escherichia coli ATCC 8739 6066637 YP_001725552.1 CDS EcolC_2594 NC_010468.1 2844623 2845879 R KEGG: sfv:SFV_1013 hypothetical protein; hypothetical protein complement(2844623..2845879) Escherichia coli ATCC 8739 6064540 YP_001725553.1 CDS EcolC_2595 NC_010468.1 2846140 2847060 D functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 2846140..2847060 Escherichia coli ATCC 8739 6065284 YP_001725554.1 CDS EcolC_2596 NC_010468.1 2847060 2847365 D with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 2847060..2847365 Escherichia coli ATCC 8739 6067629 YP_001725555.1 CDS torD NC_010468.1 2847517 2848116 R TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD complement(2847517..2848116) Escherichia coli ATCC 8739 6067080 YP_001725556.1 CDS EcolC_2598 NC_010468.1 2848113 2850659 R KEGG: sfv:SFV_1007 trimethylamine N-oxide reductase subunit; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin guanine dinucleotide-containing S/N-oxide reductase complement(2848113..2850659) Escherichia coli ATCC 8739 6066224 YP_001725557.1 CDS EcolC_2599 NC_010468.1 2850659 2851831 R TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: ssn:SSON_1004 trimethylamine N-oxide reductase, cytochrome c-type subunit; trimethylamine-N-oxide reductase c-type cytochrome TorC complement(2850659..2851831) Escherichia coli ATCC 8739 6064659 YP_001725558.1 CDS EcolC_2600 NC_010468.1 2851961 2852653 D response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 2851961..2852653 Escherichia coli ATCC 8739 6066874 YP_001725559.1 CDS EcolC_2601 NC_010468.1 2852626 2853654 R periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT complement(2852626..2853654) Escherichia coli ATCC 8739 6066895 YP_001725560.1 CDS EcolC_2602 NC_010468.1 2853767 2856481 D Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 2853767..2856481 Escherichia coli ATCC 8739 6065036 YP_001725561.1 CDS EcolC_2603 NC_010468.1 2856553 2857626 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_1002 hypothetical protein; 4Fe-4S ferredoxin 2856553..2857626 Escherichia coli ATCC 8739 6067048 YP_001725562.1 CDS EcolC_2604 NC_010468.1 2857675 2857848 R PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA; GnsAGnsB family protein complement(2857675..2857848) Escherichia coli ATCC 8739 6065104 YP_001725563.1 CDS EcolC_2605 NC_010468.1 2857838 2858068 R KEGG: ssn:SSON_0998 Sfa; cold shock gene complement(2857838..2858068) Escherichia coli ATCC 8739 6064837 YP_001725564.1 CDS EcolC_2606 NC_010468.1 2858043 2858255 R KEGG: sec:SC1999 putative cold-shock protein; putative cold-shock protein complement(2858043..2858255) Escherichia coli ATCC 8739 6065439 YP_001725565.1 CDS EcolC_2607 NC_010468.1 2858242 2858454 R PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sbo:SBO_2241 CspG; cold shock protein CspG complement(2858242..2858454) Escherichia coli ATCC 8739 6065907 YP_001725566.1 CDS EcolC_2608 NC_010468.1 2858740 2858952 D PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sdy:SDY_0964 cold shock-like protein; cold-shock DNA-binding domain-containing protein 2858740..2858952 Escherichia coli ATCC 8739 6064443 YP_001725567.1 CDS EcolC_2609 NC_010468.1 2859393 2859698 D KEGG: sdy:SDY_0963 hypothetical protein; hypothetical protein 2859393..2859698 Escherichia coli ATCC 8739 6067505 YP_001725568.1 CDS EcolC_2610 NC_010468.1 2859805 2860449 D KEGG: sbo:SBO_2244 putative regulator; putative regulator 2859805..2860449 Escherichia coli ATCC 8739 6065535 YP_001725569.1 CDS EcolC_2611 NC_010468.1 2860446 2861192 D PFAM: protein of unknown function DUF1017; KEGG: ssn:SSON_0992 hypothetical protein; hypothetical protein 2860446..2861192 Escherichia coli ATCC 8739 6066892 YP_001725570.1 CDS EcolC_2612 NC_010468.1 2861192 2863288 D PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: sbo:SBO_2246 hypothetical protein; hypothetical protein 2861192..2863288 Escherichia coli ATCC 8739 6065159 YP_001725571.1 CDS EcolC_2613 NC_010468.1 2863334 2864473 D PFAM: polysaccharide export protein; KEGG: ssn:SSON_0990 putative function in exopolysaccharide production; polysaccharide export protein 2863334..2864473 Escherichia coli ATCC 8739 6065570 YP_001725572.1 CDS etp NC_010468.1 2864461 2864907 D Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 2864461..2864907 Escherichia coli ATCC 8739 6065181 YP_001725573.1 CDS EcolC_2615 NC_010468.1 2864927 2867107 D KEGG: sbo:SBO_2249 hypothetical protein; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; cryptic autophosphorylating protein tyrosine kinase Etk 2864927..2867107 Escherichia coli ATCC 8739 6064656 YP_001725574.1 CDS EcolC_2616 NC_010468.1 2867222 2868550 R PFAM: histidine acid phosphatase; KEGG: ssn:SSON_0987 phosphoanhydride phosphorylase; phosphoanhydride phosphorylase complement(2867222..2868550) Escherichia coli ATCC 8739 6066031 YP_001725575.1 CDS EcolC_2617 NC_010468.1 2868705 2869841 R KEGG: ssn:SSON_0985 probable third cytochrome oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II complement(2868705..2869841) Escherichia coli ATCC 8739 6067059 YP_001725576.1 CDS EcolC_2618 NC_010468.1 2869853 2871397 R PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sfv:SFV_0987 probable third cytochrome oxidase, subunit I; cytochrome bd ubiquinol oxidase subunit I complement(2869853..2871397) Escherichia coli ATCC 8739 6065624 YP_001725577.1 CDS EcolC_2619 NC_010468.1 2871531 2872388 R PFAM: HupH hydrogenase expression protein; KEGG: sfx:S1045 hydrogenase-1 operon protein hyaF; HupH hydrogenase expression protein complement(2871531..2872388) Escherichia coli ATCC 8739 6066232 YP_001725578.1 CDS EcolC_2620 NC_010468.1 2872385 2872783 R involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE complement(2872385..2872783) Escherichia coli ATCC 8739 6064910 YP_001725579.1 CDS EcolC_2621 NC_010468.1 2872780 2873367 R HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease complement(2872780..2873367) Escherichia coli ATCC 8739 6064644 YP_001725580.1 CDS EcolC_2622 NC_010468.1 2873364 2874071 R TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: sdy:SDY_0949 probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit; hydrogenase 1 b-type cytochrome subunit complement(2873364..2874071) Escherichia coli ATCC 8739 6065412 YP_001725581.1 CDS EcolC_2624 NC_010468.1 2875066 2876217 D PFAM: Integrase catalytic region; KEGG: bxe:Bxe_C0741 putative transposase IS30; integrase catalytic subunit 2875066..2876217 Escherichia coli ATCC 8739 6065752 YP_001725582.1 CDS EcolC_2625 NC_010468.1 2877103 2878221 R KEGG: sdy:SDY_0947 hydrogenase-1 small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein; hydrogenase (NiFe) small subunit HydA complement(2877103..2878221) Escherichia coli ATCC 8739 6066223 YP_001725583.1 CDS EcolC_2626 NC_010468.1 2878942 2879601 D PFAM: protein of unknown function UPF0005; KEGG: sdy:SDY_0945 putative carrier/transport protein; hypothetical protein 2878942..2879601 Escherichia coli ATCC 8739 6066065 YP_001725584.1 CDS EcolC_2627 NC_010468.1 2879692 2880021 D transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 2879692..2880021 Escherichia coli ATCC 8739 6064826 YP_001725585.1 CDS EcolC_2628 NC_010468.1 2880018 2880296 R catalyzes the hydrolysis of acylphosphate; acylphosphatase complement(2880018..2880296) Escherichia coli ATCC 8739 6065184 YP_001725586.1 CDS EcolC_2629 NC_010468.1 2880391 2881581 D PFAM: conserved hypothetical protein; SMART: PUA domain containing protein; KEGG: sdy:SDY_0942 hypothetical protein; hypothetical protein 2880391..2881581 Escherichia coli ATCC 8739 6064665 YP_001725587.1 CDS EcolC_2630 NC_010468.1 2881639 2881956 D TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: sbo:SBO_2265 hypothetical protein; heat shock protein HspQ 2881639..2881956 Escherichia coli ATCC 8739 6067298 YP_001725588.1 CDS EcolC_2631 NC_010468.1 2882001 2882414 R PFAM: CoA-binding domain protein; KEGG: sbo:SBO_2266 hypothetical protein; CoA-binding domain-containing protein complement(2882001..2882414) Escherichia coli ATCC 8739 6067444 YP_001725589.1 CDS EcolC_2632 NC_010468.1 2882587 2883249 D KEGG: sdy:SDY_0939 hypothetical protein; hypothetical protein 2882587..2883249 Escherichia coli ATCC 8739 6064562 YP_001725590.1 CDS mgsA NC_010468.1 2883345 2883803 D catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 2883345..2883803 Escherichia coli ATCC 8739 6064585 YP_001725591.1 CDS helD NC_010468.1 2883835 2885889 R catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV complement(2883835..2885889) Escherichia coli ATCC 8739 6066111 YP_001725592.1 CDS EcolC_2635 NC_010468.1 2886012 2886458 D PFAM: protein of unknown function DUF307; KEGG: sbo:SBO_2270 hypothetical protein; hypothetical protein 2886012..2886458 Escherichia coli ATCC 8739 6066495 YP_001725593.1 CDS EcolC_2636 NC_010468.1 2886468 2888630 D TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_0964 hypothetical protein; hypothetical protein 2886468..2888630 Escherichia coli ATCC 8739 6066133 YP_001725594.1 CDS EcolC_2637 NC_010468.1 2888593 2889222 R PFAM: TfoX domain protein; KEGG: sdy:SDY_0934 hypothetical protein; competence-specific genes regulator complement(2888593..2889222) Escherichia coli ATCC 8739 6064522 YP_001725595.1 CDS EcolC_2638 NC_010468.1 2889441 2889950 D PFAM: cell division inhibitor SulA; KEGG: ssn:SSON_0962 suppressor of lon; inhibits cell division and FtsZ ring formation; SOS cell division inhibitor 2889441..2889950 Escherichia coli ATCC 8739 6067662 YP_001725596.1 CDS EcolC_2639 NC_010468.1 2890250 2891347 D OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 2890250..2891347 Escherichia coli ATCC 8739 6065730 YP_001725597.1 CDS EcolC_2640 NC_010468.1 2891423 2891875 R PFAM: protein of unknown function DUF1047; KEGG: sdy:SDY_0929 putative dehydrogenase; hypothetical protein complement(2891423..2891875) Escherichia coli ATCC 8739 6065371 YP_001725598.1 CDS EcolC_2641 NC_010468.1 2892061 2893821 D PFAM: peptidase S16 lon domain protein; KEGG: ssn:SSON_0959 putative ATP-dependent protease; peptidase S16 lon domain-containing protein 2892061..2893821 Escherichia coli ATCC 8739 6065885 YP_001725599.1 CDS EcolC_2642 NC_010468.1 2893890 2894408 D catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2893890..2894408 Escherichia coli ATCC 8739 6065493 YP_001725600.1 CDS EcolC_2643 NC_010468.1 2894478 2894645 R PFAM: ribosome modulation factor; KEGG: sdy:SDY_0926 ribosome modulation factor; ribosome modulation factor complement(2894478..2894645) Escherichia coli ATCC 8739 6066587 YP_001725601.1 CDS EcolC_2644 NC_010468.1 2894901 2895464 R PFAM: protein of unknown function DUF330; KEGG: sfv:SFV_0961 hypothetical protein; hypothetical protein complement(2894901..2895464) Escherichia coli ATCC 8739 6066386 YP_001725602.1 CDS EcolC_2645 NC_010468.1 2895461 2897101 R PFAM: Mammalian cell entry related domain protein; KEGG: sdy:SDY_0924 paraquat-inducible protein B; paraquat-inducible protein B complement(2895461..2897101) Escherichia coli ATCC 8739 6067438 YP_001725603.1 CDS EcolC_2646 NC_010468.1 2897106 2898359 R TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: sbo:SBO_2281 paraquat-inducible protein A; PqiA family integral membrane protein complement(2897106..2898359) Escherichia coli ATCC 8739 6066809 YP_001725604.1 CDS EcolC_2647 NC_010468.1 2898489 2900396 R Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase complement(2898489..2900396) Escherichia coli ATCC 8739 6064666 YP_001725605.1 CDS rlmL NC_010468.1 2900408 2902516 R catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase complement(2900408..2902516) Escherichia coli ATCC 8739 6064872 YP_001725606.1 CDS EcolC_2649 NC_010468.1 2902760 2903869 D PFAM: ferredoxin; MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: ssn:SSON_0951 hypothetical protein; MOSC domain-containing protein 2902760..2903869 Escherichia coli ATCC 8739 6067399 YP_001725607.1 CDS EcolC_2650 NC_010468.1 2903866 2904408 R PFAM: protein of unknown function DUF1379; KEGG: ssn:SSON_0950 hypothetical protein; hypothetical protein complement(2903866..2904408) Escherichia coli ATCC 8739 6064435 YP_001725608.1 CDS EcolC_2651 NC_010468.1 2904582 2905592 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(2904582..2905592) Escherichia coli ATCC 8739 6065395 YP_001725609.1 CDS EcolC_2652 NC_010468.1 2905703 2906413 R PFAM: pili assembly chaperone; KEGG: ssn:SSON_0948 putative chaperone; pili assembly chaperone complement(2905703..2906413) Escherichia coli ATCC 8739 6064807 YP_001725610.1 CDS EcolC_2653 NC_010468.1 2906406 2906921 R PFAM: Fimbrial protein; KEGG: ssn:SSON_0947 putative fimbrial-like protein; fimbrial protein complement(2906406..2906921) Escherichia coli ATCC 8739 6064411 YP_001725611.1 CDS EcolC_2654 NC_010468.1 2906929 2907471 R PFAM: Fimbrial protein; KEGG: sfv:SFV_0951 putative fimbrial-like protein; fimbrial protein complement(2906929..2907471) Escherichia coli ATCC 8739 6064795 YP_001725612.1 CDS EcolC_2655 NC_010468.1 2907483 2908526 R PFAM: Fimbrial protein; KEGG: ssn:SSON_0945 FimH-like protein; fimbrial protein complement(2907483..2908526) Escherichia coli ATCC 8739 6064444 YP_001725613.1 CDS EcolC_2657 NC_010468.1 2911168 2911869 R PFAM: pili assembly chaperone; KEGG: ssn:SSON_0943 putative chaperone; pili assembly chaperone complement(2911168..2911869) Escherichia coli ATCC 8739 6067217 YP_001725614.1 CDS EcolC_2658 NC_010468.1 2911952 2912491 R PFAM: Fimbrial protein; KEGG: ssn:SSON_0942 putative fimbrial-like protein; fimbrial protein complement(2911952..2912491) Escherichia coli ATCC 8739 6066964 YP_001725615.1 CDS EcolC_2659 NC_010468.1 2912847 2913422 D PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2228 hypothetical protein; NAD(P)H-dependent FMN reductase 2912847..2913422 Escherichia coli ATCC 8739 6066868 YP_001725616.1 CDS EcolC_2660 NC_010468.1 2913415 2914374 D part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 2913415..2914374 Escherichia coli ATCC 8739 6065549 YP_001725617.1 CDS EcolC_2661 NC_010468.1 2914371 2915516 D catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 2914371..2915516 Escherichia coli ATCC 8739 6067484 YP_001725618.1 CDS ssuC NC_010468.1 2915527 2916318 D part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 2915527..2916318 Escherichia coli ATCC 8739 6066525 YP_001725619.1 CDS ssuB NC_010468.1 2916315 2917082 D part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 2916315..2917082 Escherichia coli ATCC 8739 6065366 YP_001725620.1 CDS pepN NC_010468.1 2917125 2919737 R TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: sbo:SBO_2223 aminopeptidase N; aminopeptidase N complement(2917125..2919737) Escherichia coli ATCC 8739 6064622 YP_001725621.1 CDS EcolC_2665 NC_010468.1 2919955 2921205 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2919955..2921205 Escherichia coli ATCC 8739 6065100 YP_001725622.1 CDS asnC NC_010468.1 2921374 2922774 D catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 2921374..2922774 Escherichia coli ATCC 8739 6066122 YP_001725623.1 CDS EcolC_2667 NC_010468.1 2923376 2924464 D outer membrane porin F; 1a; Ia; b; outer membrane protein F 2923376..2924464 Escherichia coli ATCC 8739 6067636 YP_001725624.1 CDS EcolC_2668 NC_010468.1 2924649 2925839 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 2924649..2925839 Escherichia coli ATCC 8739 6066780 YP_001725625.1 CDS EcolC_2669 NC_010468.1 2926061 2926708 R PFAM: beta-lactamase domain protein; KEGG: sbo:SBO_2218 hypothetical protein; beta-lactamase domain-containing protein complement(2926061..2926708) Escherichia coli ATCC 8739 6065874 YP_001725626.1 CDS EcolC_2670 NC_010468.1 2926735 2927283 R PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: sdy:SDY_2331 hypothetical protein; hypothetical protein complement(2926735..2927283) Escherichia coli ATCC 8739 6066309 YP_001725627.1 CDS EcolC_2671 NC_010468.1 2927464 2929311 R PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sbo:SBO_2216 putative amidase; hypothetical protein complement(2927464..2929311) Escherichia coli ATCC 8739 6065460 YP_001725628.1 CDS mukB NC_010468.1 2929572 2934032 R SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB complement(2929572..2934032) Escherichia coli ATCC 8739 6065096 YP_001725629.1 CDS EcolC_2673 NC_010468.1 2934032 2934736 R acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E complement(2934032..2934736) Escherichia coli ATCC 8739 6065798 YP_001725630.1 CDS EcolC_2674 NC_010468.1 2934717 2936039 R acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F complement(2934717..2936039) Escherichia coli ATCC 8739 6065477 YP_001725631.1 CDS EcolC_2675 NC_010468.1 2936036 2936821 R involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA complement(2936036..2936821) Escherichia coli ATCC 8739 6067038 YP_001725632.1 CDS EcolC_2676 NC_010468.1 2936957 2937736 D PFAM: protein of unknown function DUF218; KEGG: sfv:SFV_0921 hypothetical protein; hypothetical protein 2936957..2937736 Escherichia coli ATCC 8739 6065449 YP_001725633.1 CDS EcolC_2677 NC_010468.1 2937713 2938606 R KEGG: sbo:SBO_2207 hypothetical protein; hypothetical protein complement(2937713..2938606) Escherichia coli ATCC 8739 6067572 YP_001725634.1 CDS EcolC_2678 NC_010468.1 2938760 2939506 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(2938760..2939506) Escherichia coli ATCC 8739 6065401 YP_001725635.1 CDS EcolC_2679 NC_010468.1 2939503 2939685 R PFAM: protein of unknown function DUF343; KEGG: sdy:SDY_2341 hypothetical protein; hypothetical protein complement(2939503..2939685) Escherichia coli ATCC 8739 6066307 YP_001725636.1 CDS EcolC_2680 NC_010468.1 2939737 2940969 R PFAM: protein of unknown function DUF1006; KEGG: sdy:SDY_2342 hypothetical protein; hypothetical protein complement(2939737..2940969) Escherichia coli ATCC 8739 6065633 YP_001725637.1 CDS lpxK NC_010468.1 2941006 2941992 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(2941006..2941992) Escherichia coli ATCC 8739 6066672 YP_001725638.1 CDS EcolC_2682 NC_010468.1 2941989 2943737 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease complement(2941989..2943737) Escherichia coli ATCC 8739 6064648 YP_001725639.1 CDS EcolC_2683 NC_010468.1 2943774 2946038 R TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: sdy:SDY_2345 hypothetical protein; hypothetical protein complement(2943774..2946038) Escherichia coli ATCC 8739 6066407 YP_001725640.1 CDS ihfB NC_010468.1 2946246 2946530 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(2946246..2946530) Escherichia coli ATCC 8739 6065915 YP_001725641.1 CDS rpsA NC_010468.1 2946690 2948363 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(2946690..2948363) Escherichia coli ATCC 8739 6065333 YP_001725642.1 CDS cmk NC_010468.1 2948474 2949157 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(2948474..2949157) Escherichia coli ATCC 8739 6066310 YP_001725643.1 CDS EcolC_2687 NC_010468.1 2949330 2950094 R PFAM: peptidase M48 Ste24p; KEGG: ssn:SSON_0911 putative heat shock protein; peptidase M48 Ste24p complement(2949330..2950094) Escherichia coli ATCC 8739 6066220 YP_001725644.1 CDS EcolC_2688 NC_010468.1 2950263 2951546 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(2950263..2951546) Escherichia coli ATCC 8739 6066710 YP_001725645.1 CDS EcolC_2689 NC_010468.1 2951617 2952705 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(2951617..2952705) Escherichia coli ATCC 8739 6066377 YP_001725646.1 CDS EcolC_2690 NC_010468.1 2952904 2953596 R PFAM: protein of unknown function DUF421; KEGG: sbo:SBO_2192 hypothetical protein; hypothetical protein complement(2952904..2953596) Escherichia coli ATCC 8739 6064483 YP_001725647.1 CDS EcolC_2691 NC_010468.1 2953726 2955486 D PFAM: protein of unknown function DUF181; KEGG: sbo:SBO_2191 hypothetical protein; hypothetical protein 2953726..2955486 Escherichia coli ATCC 8739 6067591 YP_001725648.1 CDS EcolC_2692 NC_010468.1 2955892 2956749 D PFAM: formate/nitrite transporter; KEGG: sdy:SDY_2357 probable formate transporter; formate transporter 2955892..2956749 Escherichia coli ATCC 8739 6064555 YP_001725649.1 CDS EcolC_2693 NC_010468.1 2956804 2959086 D KEGG: ssn:SSON_0904 formate acetyltransferase 1; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; formate acetyltransferase 2956804..2959086 Escherichia coli ATCC 8739 6066389 YP_001725650.1 CDS pflA NC_010468.1 2959278 2960018 D activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 2959278..2960018 Escherichia coli ATCC 8739 6065768 YP_001725651.1 CDS EcolC_2695 NC_010468.1 2960100 2960690 R PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2185 hypothetical protein; hypothetical protein complement(2960100..2960690) Escherichia coli ATCC 8739 6066399 YP_001725652.1 CDS EcolC_2696 NC_010468.1 2960790 2961698 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_2184 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 2960790..2961698 Escherichia coli ATCC 8739 6065708 YP_001725653.1 CDS EcolC_2697 NC_010468.1 2961699 2963129 R PFAM: amino acid permease-associated region; KEGG: stm:STM0969 putative amino-acid transporter; amino acid permease-associated protein complement(2961699..2963129) Escherichia coli ATCC 8739 6067061 YP_001725654.1 CDS EcolC_2698 NC_010468.1 2963339 2964487 R PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_2363 putative transport; putative MFS family transporter protein complement(2963339..2964487) Escherichia coli ATCC 8739 6065426 YP_001725655.1 CDS EcolC_2699 NC_010468.1 2964801 2965427 D PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_0898 hypothetical protein; isochorismatase hydrolase 2964801..2965427 Escherichia coli ATCC 8739 6067517 YP_001725656.1 CDS EcolC_2700 NC_010468.1 2965462 2966325 R PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_0985 anaerobic dimethyl sulfoxide reductase subunit C; DMSO reductase anchor subunit DmsC complement(2965462..2966325) Escherichia coli ATCC 8739 6067192 YP_001725657.1 CDS EcolC_2701 NC_010468.1 2966327 2966944 R TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_0896 anaerobic dimethyl sulfoxide reductase subunit B; dimethylsulfoxide reductase subunit B complement(2966327..2966944) Escherichia coli ATCC 8739 6065729 YP_001725658.1 CDS EcolC_2702 NC_010468.1 2966955 2969399 R TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: ssn:SSON_0895 anaerobic dimethyl sulfoxide reductase subunit A; anaerobic dimethyl sulfoxide reductase subunit A complement(2966955..2969399) Escherichia coli ATCC 8739 6065590 YP_001725659.1 CDS EcolC_2703 NC_010468.1 2969638 2970930 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(2969638..2970930) Escherichia coli ATCC 8739 6067125 YP_001725660.1 CDS EcolC_2704 NC_010468.1 2971021 2972364 R PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: sdy:SDY_2369 putative polynucleotide enzyme; recombination factor protein RarA complement(2971021..2972364) Escherichia coli ATCC 8739 6065710 YP_001725661.1 CDS lolA NC_010468.1 2972375 2972986 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(2972375..2972986) Escherichia coli ATCC 8739 6066662 YP_001725662.1 CDS EcolC_2706 NC_010468.1 2973141 2977130 R DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK complement(2973141..2977130) Escherichia coli ATCC 8739 6065818 YP_001725663.1 CDS EcolC_2707 NC_010468.1 2977265 2977759 R mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator complement(2977265..2977759) Escherichia coli ATCC 8739 6065592 YP_001725664.1 CDS EcolC_2708 NC_010468.1 2978304 2979269 D catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 2978304..2979269 Escherichia coli ATCC 8739 6065088 YP_001725665.1 CDS EcolC_2709 NC_010468.1 2979392 2981158 D in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 2979392..2981158 Escherichia coli ATCC 8739 6064814 YP_001725666.1 CDS EcolC_2710 NC_010468.1 2981159 2982880 D in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 2981159..2982880 Escherichia coli ATCC 8739 6066944 YP_001725667.1 CDS aat NC_010468.1 2982922 2983626 D leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 2982922..2983626 Escherichia coli ATCC 8739 6067642 YP_001725668.1 CDS infA NC_010468.1 2983911 2984129 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2983911..2984129 Escherichia coli ATCC 8739 6067646 YP_001725669.1 CDS EcolC_2714 NC_010468.1 2986831 2987528 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(2986831..2987274,2987274..2987528)) Escherichia coli ATCC 8739 6064735 YP_001725670.1 CDS clpS NC_010468.1 2988011 2988331 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(2988011..2988331) Escherichia coli ATCC 8739 6067613 YP_001725671.1 CDS EcolC_2716 NC_010468.1 2988654 2988878 D inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 2988654..2988878 Escherichia coli ATCC 8739 6067416 YP_001725672.1 CDS EcolC_2717 NC_010468.1 2988951 2990897 R with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease complement(2988951..2990897) Escherichia coli ATCC 8739 6067230 YP_001725673.1 CDS EcolC_2718 NC_010468.1 2990894 2992009 R confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA complement(2990894..2992009) Escherichia coli ATCC 8739 6066808 YP_001725674.1 CDS EcolC_2719 NC_010468.1 2992124 2993116 D PFAM: protein of unknown function DUF535; KEGG: ssn:SSON_0864 putative enzyme; hypothetical protein 2992124..2993116 Escherichia coli ATCC 8739 6066734 YP_001725675.1 CDS EcolC_2720 NC_010468.1 2993113 2994771 R KEGG: sfx:S0876 predicted ATP-dependent endonuclease of the OLD family; ATP-dependent OLD family endonuclease complement(2993113..2994771) Escherichia coli ATCC 8739 6066620 YP_001725676.1 CDS EcolC_2721 NC_010468.1 2995196 2995891 D porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 2995196..2995891 Escherichia coli ATCC 8739 6066518 YP_001725677.1 CDS EcolC_2722 NC_010468.1 2996386 2997285 D PFAM: protein of unknown function DUF340 membrane; KEGG: sbo:SBO_0807 putative surface protein; hypothetical protein 2996386..2997285 Escherichia coli ATCC 8739 6066464 YP_001725678.1 CDS EcolC_2723 NC_010468.1 2997429 2999081 D catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 2997429..2999081 Escherichia coli ATCC 8739 6066423 YP_001725679.1 CDS EcolC_2724 NC_010468.1 2999093 3000061 D PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ssn:SSON_0858 putative enzyme; HCP oxidoreductase 2999093..3000061 Escherichia coli ATCC 8739 6066329 YP_001725680.1 CDS EcolC_2725 NC_010468.1 3000194 3001912 D catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 3000194..3001912 Escherichia coli ATCC 8739 6066040 YP_001725681.1 CDS EcolC_2726 NC_010468.1 3001949 3002950 D low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 3001949..3002950 Escherichia coli ATCC 8739 6065806 YP_001725682.1 CDS EcolC_2727 NC_010468.1 3002961 3004391 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sbo:SBO_0802 putative dTDP-glucose enzyme; NAD-dependent epimerase/dehydratase 3002961..3004391 Escherichia coli ATCC 8739 6064912 YP_001725683.1 CDS EcolC_2728 NC_010468.1 3004454 3005503 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: ssn:SSON_0854 putative nucleotide di-P-sugar epimerase or dehydratase; NAD-dependent epimerase/dehydratase 3004454..3005503 Escherichia coli ATCC 8739 6064962 YP_001725684.1 CDS EcolC_2729 NC_010468.1 3005500 3006330 R PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sdy:SDY_2396 putative regulator; N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD complement(3005500..3006330) Escherichia coli ATCC 8739 6065038 YP_001725685.1 CDS EcolC_2730 NC_010468.1 3006327 3006650 R PFAM: protein of unknown function DUF74; KEGG: sdy:SDY_2397 hypothetical protein; hypothetical protein complement(3006327..3006650) Escherichia coli ATCC 8739 6066843 YP_001725686.1 CDS EcolC_2731 NC_010468.1 3006776 3007291 D induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein 3006776..3007291 Escherichia coli ATCC 8739 6067648 YP_001725687.1 CDS artP NC_010468.1 3007509 3008237 D With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 3007509..3008237 Escherichia coli ATCC 8739 6067450 YP_001725688.1 CDS EcolC_2733 NC_010468.1 3008255 3008986 D KEGG: sbo:SBO_0797 arginine 3rd transport system periplasmic binding protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; cationic amino acid ABC transporter periplasmic binding protein 3008255..3008986 Escherichia coli ATCC 8739 6067281 YP_001725689.1 CDS EcolC_2734 NC_010468.1 3008993 3009709 D with ArtPMJI transports arginine across the inner membrane; arginine transporter permease ArtQ 3008993..3009709 Escherichia coli ATCC 8739 6066971 YP_001725690.1 CDS artM NC_010468.1 3009709 3010377 D with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease ArtM 3009709..3010377 Escherichia coli ATCC 8739 6066706 YP_001725691.1 CDS EcolC_2736 NC_010468.1 3010603 3011334 D KEGG: sbo:SBO_0794 arginine 3rd transport system periplasmic binding protein; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; cationic amino acid ABC transporter periplasmic binding protein 3010603..3011334 Escherichia coli ATCC 8739 6066159 YP_001725692.1 CDS rumB NC_010468.1 3011533 3012660 R RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase complement(3011533..3012660) Escherichia coli ATCC 8739 6065898 YP_001725693.1 CDS EcolC_2738 NC_010468.1 3012701 3013189 R KEGG: sdy:SDY_0737 hypothetical protein; hypothetical protein complement(3012701..3013189) Escherichia coli ATCC 8739 6065887 YP_001725694.1 CDS EcolC_2739 NC_010468.1 3013249 3014094 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_0738 putrescine transport protein; putrescine ABC transporter membrane protein complement(3013249..3014094) Escherichia coli ATCC 8739 6065714 YP_001725695.1 CDS EcolC_2740 NC_010468.1 3014091 3015044 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfx:S0852 putrescine transport protein; permease; putrescine ABC transporter membrane protein complement(3014091..3015044) Escherichia coli ATCC 8739 6065690 YP_001725696.1 CDS potG NC_010468.1 3015054 3016187 R part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein complement(3015054..3016187) Escherichia coli ATCC 8739 6065567 YP_001725697.1 CDS EcolC_2742 NC_010468.1 3016282 3017394 R PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_0788 periplasmic putrescine-binding protein; putrescine ABC transporter periplasmic-binding protein complement(3016282..3017394) Escherichia coli ATCC 8739 6065194 YP_001725698.1 CDS EcolC_2743 NC_010468.1 3017745 3018221 R KEGG: sbo:SBO_0787 putative sensory transduction regulator; putative sensory transduction regulator complement(3017745..3018221) Escherichia coli ATCC 8739 6064906 YP_001725699.1 CDS EcolC_2744 NC_010468.1 3018309 3019211 R responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein complement(3018309..3019211) Escherichia coli ATCC 8739 6064780 YP_001725700.1 CDS EcolC_2745 NC_010468.1 3019272 3019994 R NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A complement(3019272..3019994) Escherichia coli ATCC 8739 6064707 YP_001725701.1 CDS EcolC_2746 NC_010468.1 3019978 3020265 R YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein complement(3019978..3020265) Escherichia coli ATCC 8739 6064667 YP_001725702.1 CDS grxA NC_010468.1 3020425 3020682 D functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 3020425..3020682 Escherichia coli ATCC 8739 6066103 YP_001725703.1 CDS EcolC_2748 NC_010468.1 3020712 3021089 R KEGG: sdy:SDY_0747 hypothetical protein; hypothetical protein complement(3020712..3021089) Escherichia coli ATCC 8739 6065214 YP_001725704.1 CDS EcolC_2749 NC_010468.1 3021359 3023044 D TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: ssn:SSON_0832 putative transport protein; hypothetical protein 3021359..3023044 Escherichia coli ATCC 8739 6065377 YP_001725705.1 CDS EcolC_2750 NC_010468.1 3023280 3023498 R PFAM: transcriptional activator Ogr/delta; KEGG: sbo:SBO_0780 putative bacteriophage late gene regulator; transcriptional activator Ogr/delta complement(3023280..3023498) Escherichia coli ATCC 8739 6066747 YP_001725706.1 CDS EcolC_2751 NC_010468.1 3023589 3024689 R PFAM: late control D family protein; KEGG: stt:t3444 putative regulator of late gene expression; late control D family protein complement(3023589..3024689) Escherichia coli ATCC 8739 6065632 YP_001725707.1 CDS EcolC_2752 NC_010468.1 3024686 3025171 R PFAM: P2 GpU family protein; KEGG: sbo:SBO_0778 putative bacteriophage tail protein; P2 GpU family protein complement(3024686..3025171) Escherichia coli ATCC 8739 6064973 YP_001725708.1 CDS EcolC_2753 NC_010468.1 3025168 3028245 R TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: stt:t2662 putative bacteriophage tail protein; TP901 family phage tail tape measure protein complement(3025168..3028245) Escherichia coli ATCC 8739 6066221 YP_001725709.1 CDS EcolC_2754 NC_010468.1 3028372 3028674 R PFAM: tail E family protein; KEGG: sbo:SBO_0776 putative phage tail protein; tail E family protein complement(3028372..3028674) Escherichia coli ATCC 8739 6065226 YP_001725710.1 CDS EcolC_2755 NC_010468.1 3028729 3029244 R TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: sbo:SBO_0775 probable major tail tube protein; phage major tail tube protein complement(3028729..3029244) Escherichia coli ATCC 8739 6067431 YP_001725711.1 CDS EcolC_2756 NC_010468.1 3029254 3030426 R PFAM: tail sheath protein; KEGG: sbo:SBO_0774 probable major tail sheath protein; tail sheath protein complement(3029254..3030426) Escherichia coli ATCC 8739 6065615 YP_001725712.1 CDS EcolC_2757 NC_010468.1 3030569 3031135 R PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: sbo:SBO_0773 inversion of adjacent DNA; at locus of E14 element; resolvase domain-containing protein complement(3030569..3031135) Escherichia coli ATCC 8739 6067229 YP_001725713.1 CDS EcolC_2758 NC_010468.1 3031163 3031696 D PFAM: Tail Collar domain protein; KEGG: stt:t1351 bacteriophage tail fiber protein; tail collar domain-containing protein 3031163..3031696 Escherichia coli ATCC 8739 6064768 YP_001725714.1 CDS EcolC_2759 NC_010468.1 3031696 3032298 D PFAM: tail assembly chaperone gp38; KEGG: stt:t1349 putative bacteriophage tail fiber assembly protein; tail assembly chaperone gp38 3031696..3032298 Escherichia coli ATCC 8739 6064773 YP_001725715.1 CDS EcolC_2760 NC_010468.1 3032270 3032689 R PFAM: tail assembly chaperone gp38; KEGG: sbo:SBO_0772 hypothetical protein; tail assembly chaperone gp38 complement(3032270..3032689) Escherichia coli ATCC 8739 6064782 YP_001725716.1 CDS EcolC_2761 NC_010468.1 3032686 3034107 R KEGG: stt:t3433 probable variable tail fiber protein; phage-related tail fiber protein-like protein complement(3032686..3034107) Escherichia coli ATCC 8739 6064783 YP_001725717.1 CDS EcolC_2762 NC_010468.1 3034104 3034709 R TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: stt:t4306 putative phage tail protein; phage tail protein I complement(3034104..3034709) Escherichia coli ATCC 8739 6064790 YP_001725718.1 CDS EcolC_2763 NC_010468.1 3034702 3035610 R PFAM: Baseplate J family protein; KEGG: stt:t3431 phage baseplate assembly protein; baseplate J family protein complement(3034702..3035610) Escherichia coli ATCC 8739 6064797 YP_001725719.1 CDS EcolC_2764 NC_010468.1 3035597 3035956 R PFAM: GPW/gp25 family protein; KEGG: stt:t3430 phage baseplate assembly protein; GPW/gp25 family protein complement(3035597..3035956) Escherichia coli ATCC 8739 6064802 YP_001725720.1 CDS EcolC_2765 NC_010468.1 3035953 3036531 R TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: stt:t3429 putative phage baseplate assembly protein; phage baseplate assembly protein V complement(3035953..3036531) Escherichia coli ATCC 8739 6064805 YP_001725721.1 CDS EcolC_2766 NC_010468.1 3036658 3038169 R KEGG: dps:DP2013 hypothetical protein; hypothetical protein complement(3036658..3038169) Escherichia coli ATCC 8739 6064812 YP_001725722.1 CDS EcolC_2767 NC_010468.1 3038257 3038721 R TIGRFAM: phage virion morphogenesis protein; PFAM: virion morphogenesis (putative tail completion) protein; KEGG: stt:t3428 putative phage tail protein; phage virion morphogenesis protein complement(3038257..3038721) Escherichia coli ATCC 8739 6064816 YP_001725723.1 CDS EcolC_2768 NC_010468.1 3038714 3039145 R PFAM: P2 phage tail completion R family protein; KEGG: stt:t3427 putative phage tail protein; P2 phage tail completion R family protein complement(3038714..3039145) Escherichia coli ATCC 8739 6064821 YP_001725724.1 CDS EcolC_2769 NC_010468.1 3039241 3039669 R KEGG: stm:STM2714 lysis-like protein; lysis-like protein complement(3039241..3039669) Escherichia coli ATCC 8739 6064824 YP_001725725.1 CDS EcolC_2770 NC_010468.1 3039666 3040181 R PFAM: glycoside hydrolase family 24; KEGG: sbo:SBO_0765 putative lysozyme protein R of prophage CP-933K; glycoside hydrolase family protein complement(3039666..3040181) Escherichia coli ATCC 8739 6064831 YP_001725726.1 CDS EcolC_2771 NC_010468.1 3040162 3040377 R KEGG: stt:t3423 possible secretory protein; putative secretory protein complement(3040162..3040377) Escherichia coli ATCC 8739 6064835 YP_001725727.1 CDS EcolC_2772 NC_010468.1 3040381 3040584 R PFAM: tail X family protein; KEGG: stt:t3422 probable phage tail protein; tail X family protein complement(3040381..3040584) Escherichia coli ATCC 8739 6064836 YP_001725728.1 CDS EcolC_2773 NC_010468.1 3040584 3041048 R PFAM: head completion protein; KEGG: sbo:SBO_0762 putative capsid completion protein; head completion protein complement(3040584..3041048) Escherichia coli ATCC 8739 6064846 YP_001725729.1 CDS EcolC_2774 NC_010468.1 3041144 3041794 R PFAM: small terminase subunit; KEGG: stt:t3420 terminase, endonuclease subunit; small terminase subunit complement(3041144..3041794) Escherichia coli ATCC 8739 6064851 YP_001725730.1 CDS EcolC_2775 NC_010468.1 3041798 3042856 R TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: stt:t3419 major capsid protein; P2 family phage major capsid protein complement(3041798..3042856) Escherichia coli ATCC 8739 6064857 YP_001725731.1 CDS EcolC_2776 NC_010468.1 3042873 3043706 R PFAM: capsid scaffolding; KEGG: stt:t3418 putative capsid scaffolding protein; capsid scaffolding complement(3042873..3043706) Escherichia coli ATCC 8739 6064858 YP_001725732.1 CDS EcolC_2777 NC_010468.1 3043849 3045615 D PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: stt:t3417 terminase, ATPase subunit; hypothetical protein 3043849..3045615 Escherichia coli ATCC 8739 6064863 YP_001725733.1 CDS EcolC_2778 NC_010468.1 3045615 3046640 D TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: stt:t3416 probable capsid portal protein; PBSX family phage portal protein 3045615..3046640 Escherichia coli ATCC 8739 6064866 YP_001725734.1 CDS EcolC_2779 NC_010468.1 3047010 3047660 R hypothetical protein complement(3047010..3047660) Escherichia coli ATCC 8739 6064874 YP_001725735.1 CDS EcolC_2780 NC_010468.1 3047666 3048361 R KEGG: cbe:Cbei_0882 hypothetical protein; hypothetical protein complement(3047666..3048361) Escherichia coli ATCC 8739 6064875 YP_001725736.1 CDS EcolC_2781 NC_010468.1 3048642 3049319 R KEGG: stm:STM2726 hypothetical protein; hypothetical protein complement(3048642..3049319) Escherichia coli ATCC 8739 6064881 YP_001725737.1 CDS EcolC_2782 NC_010468.1 3049433 3049666 R PFAM: DinI family protein; KEGG: sbo:SBO_0753 putative damage-inducible protein; DinI family protein complement(3049433..3049666) Escherichia coli ATCC 8739 6064886 YP_001725738.1 CDS EcolC_2783 NC_010468.1 3049677 3049865 R KEGG: stt:t3411 hypothetical protein; hypothetical protein complement(3049677..3049865) Escherichia coli ATCC 8739 6064892 YP_001725739.1 CDS EcolC_2784 NC_010468.1 3050018 3052390 R PFAM: replication gene A; KEGG: stt:t3410 possible endonuclease; replication gene A complement(3050018..3052390) Escherichia coli ATCC 8739 6064893 YP_001725740.1 CDS EcolC_2785 NC_010468.1 3052390 3053211 R KEGG: eba:ebA7273 hypothetical protein; hypothetical protein complement(3052390..3053211) Escherichia coli ATCC 8739 6064896 YP_001725741.1 CDS EcolC_2786 NC_010468.1 3053217 3054071 R KEGG: stt:t3409 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; DNA adenine methylase complement(3053217..3054071) Escherichia coli ATCC 8739 6064901 YP_001725742.1 CDS EcolC_2787 NC_010468.1 3054068 3054295 R TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: stt:t3408 hypothetical protein; TraR/DksA family transcriptional regulator complement(3054068..3054295) Escherichia coli ATCC 8739 6064904 YP_001725743.1 CDS EcolC_2788 NC_010468.1 3054295 3054528 R KEGG: stt:t3407 hypothetical protein; hypothetical protein complement(3054295..3054528) Escherichia coli ATCC 8739 6064909 YP_001725744.1 CDS EcolC_2789 NC_010468.1 3054596 3054937 R KEGG: stt:t3406 hypothetical protein; hypothetical protein complement(3054596..3054937) Escherichia coli ATCC 8739 6064914 YP_001725745.1 CDS EcolC_2790 NC_010468.1 3054901 3055101 R KEGG: ent:Ent638_1345 hypothetical protein; hypothetical protein complement(3054901..3055101) Escherichia coli ATCC 8739 6064916 YP_001725746.1 CDS EcolC_2791 NC_010468.1 3055109 3055618 R PFAM: regulatory CII family protein; KEGG: stt:t3404 regulatory protein CII; regulatory CII family protein complement(3055109..3055618) Escherichia coli ATCC 8739 6064918 YP_001725747.1 CDS EcolC_2792 NC_010468.1 3055651 3055872 R KEGG: sbo:SBO_0749 hypothetical protein; hypothetical protein complement(3055651..3055872) Escherichia coli ATCC 8739 6064925 YP_001725748.1 CDS EcolC_2793 NC_010468.1 3055998 3056567 D PFAM: CI repressor; KEGG: sbo:SBO_0748 repressor protein; CI repressor 3055998..3056567 Escherichia coli ATCC 8739 6064928 YP_001725749.1 CDS EcolC_2794 NC_010468.1 3056583 3056774 D KEGG: sdy:SDY_1763 hypothetical protein; hypothetical protein 3056583..3056774 Escherichia coli ATCC 8739 6064929 YP_001725750.1 CDS EcolC_2795 NC_010468.1 3056961 3058013 D PFAM: integrase family protein; KEGG: stt:t3400 probable bacteriophage integrase; integrase family protein 3056961..3058013 Escherichia coli ATCC 8739 6064946 YP_001725751.1 CDS EcolC_2796 NC_010468.1 3058118 3058654 R PFAM: regulatory protein TetR; KEGG: sbo:SBO_0742 putative DeoR-type transcriptional regulator; TetR family transcriptional regulator complement(3058118..3058654) Escherichia coli ATCC 8739 6064947 YP_001725752.1 CDS EcolC_2797 NC_010468.1 3058819 3059946 D PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_0741 putative DeoR-type transcriptional regulator; major facilitator transporter 3058819..3059946 Escherichia coli ATCC 8739 6064949 YP_001725753.1 CDS EcolC_2798 NC_010468.1 3059946 3060761 D KEGG: sfv:SFV_0829 hypothetical protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3; cof family hydrolase 3059946..3060761 Escherichia coli ATCC 8739 6064954 YP_001725754.1 CDS EcolC_2799 NC_010468.1 3060847 3061131 D KEGG: sbo:SBO_0739 hypothetical protein; hypothetical protein 3060847..3061131 Escherichia coli ATCC 8739 6064958 YP_001725755.1 CDS EcolC_2800 NC_010468.1 3061172 3062404 R PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0838 chloramphenicol resistance pump Cmr; major facilitator transporter complement(3061172..3062404) Escherichia coli ATCC 8739 6064960 YP_001725756.1 CDS EcolC_2801 NC_010468.1 3062689 3063285 D PFAM: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_0826 hypothetical protein; undecaprenyl pyrophosphate phosphatase 3062689..3063285 Escherichia coli ATCC 8739 6064970 YP_001725757.1 CDS EcolC_2802 NC_010468.1 3063343 3064101 D PFAM: regulatory protein DeoR; KEGG: sfv:SFV_0825 transcriptional repressor for deo operon, tsx, NupG; DNA-binding transcriptional repressor DeoR 3063343..3064101 Escherichia coli ATCC 8739 6064987 YP_001725758.1 CDS EcolC_2803 NC_010468.1 3064148 3065350 R penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(3064148..3065350) Escherichia coli ATCC 8739 6064990 YP_001725759.1 CDS EcolC_2804 NC_010468.1 3065597 3066223 D PFAM: Glutathione S-transferase domain; KEGG: sfx:S0831 putative transferase; glutathione S-transferase domain-containing protein 3065597..3066223 Escherichia coli ATCC 8739 6064993 YP_001725760.1 CDS EcolC_2805 NC_010468.1 3066220 3067335 R PFAM: glucose sorbosone dehydrogenase; KEGG: sbo:SBO_0733 putative dehydrogenase; glucose sorbosone dehydrogenase complement(3066220..3067335) Escherichia coli ATCC 8739 6064995 YP_001725761.1 CDS bssR NC_010468.1 3067446 3067829 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR complement(3067446..3067829) Escherichia coli ATCC 8739 6064999 YP_001725762.1 CDS rimO NC_010468.1 3068042 3069367 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 3068042..3069367 Escherichia coli ATCC 8739 6065001 YP_001725763.1 CDS EcolC_2808 NC_010468.1 3069593 3069979 D PFAM: protein of unknown function DUF1044; KEGG: plu:plu2130 hypothetical protein; hypothetical protein 3069593..3069979 Escherichia coli ATCC 8739 6064521 YP_001725764.1 CDS EcolC_2809 NC_010468.1 3069969 3070298 D PFAM: helix-turn-helix domain protein; KEGG: shn:Shewana3_4237 transcriptional regulator, XRE family; XRE family transcriptional regulator 3069969..3070298 Escherichia coli ATCC 8739 6065000 YP_001725765.1 CDS EcolC_2810 NC_010468.1 3070368 3071696 R TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbo:SBO_0726 hypothetical protein; diguanylate cyclase complement(3070368..3071696) Escherichia coli ATCC 8739 6065018 YP_001725766.1 CDS EcolC_2811 NC_010468.1 3071704 3074052 R PFAM: EAL domain protein; KEGG: sfv:SFV_0816 hypothetical protein; diguanylate phosphodiesterase complement(3071704..3074052) Escherichia coli ATCC 8739 6065025 YP_001725767.1 CDS EcolC_2812 NC_010468.1 3074230 3075141 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbo:SBO_0722 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein complement(3074230..3075141) Escherichia coli ATCC 8739 6065029 YP_001725768.1 CDS EcolC_2813 NC_010468.1 3075144 3076064 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_0756 putative transport system permease protein; binding-protein-dependent transport system inner membrane protein complement(3075144..3076064) Escherichia coli ATCC 8739 6065031 YP_001725769.1 CDS EcolC_2814 NC_010468.1 3076082 3077620 R PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_0720 putative transport protein; extracellular solute-binding protein complement(3076082..3077620) Escherichia coli ATCC 8739 6065034 YP_001725770.1 CDS EcolC_2815 NC_010468.1 3077640 3079511 R with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein complement(3077640..3079511) Escherichia coli ATCC 8739 6065035 YP_001725771.1 CDS EcolC_2816 NC_010468.1 3079498 3080463 R PFAM: peptidase T2 asparaginase 2; KEGG: sfx:S0821 putative asparaginase; L-asparaginase complement(3079498..3080463) Escherichia coli ATCC 8739 6065046 YP_001725772.1 CDS EcolC_2817 NC_010468.1 3080667 3081902 D is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 3080667..3081902 Escherichia coli ATCC 8739 6065049 YP_001725773.1 CDS EcolC_2818 NC_010468.1 3081902 3082651 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 3081902..3082651 Escherichia coli ATCC 8739 6065056 YP_001725774.1 CDS EcolC_2819 NC_010468.1 3082727 3083389 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(3082727..3083389) Escherichia coli ATCC 8739 6064883 YP_001725775.1 CDS EcolC_2820 NC_010468.1 3083520 3084419 D KEGG: sfv:SFV_0807 putative pyruvate formate-lyase 2 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein; glycyl-radical activating family protein 3083520..3084419 Escherichia coli ATCC 8739 6065067 YP_001725776.1 CDS EcolC_2821 NC_010468.1 3084425 3086857 D KEGG: ssn:SSON_0805 putative formate acetyltransferase; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; pyruvate formate-lyase 3084425..3086857 Escherichia coli ATCC 8739 6065071 YP_001725777.1 CDS EcolC_2822 NC_010468.1 3086997 3087812 D KEGG: sfv:SFV_0805 hypothetical protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; cof family hydrolase 3086997..3087812 Escherichia coli ATCC 8739 6065072 YP_001725778.1 CDS EcolC_2823 NC_010468.1 3088845 3090437 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0710 putative ATP-binding component of a transport system; ABC transporter-like protein complement(3088845..3090437) Escherichia coli ATCC 8739 6065075 YP_001725779.1 CDS EcolC_2824 NC_010468.1 3090656 3091576 D PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_0777 hypothetical protein; hypothetical protein 3090656..3091576 Escherichia coli ATCC 8739 6065078 YP_001725780.1 CDS EcolC_2825 NC_010468.1 3091635 3092753 R PFAM: Citrate transporter; KEGG: ssn:SSON_0797 hypothetical protein; citrate transporter complement(3091635..3092753) Escherichia coli ATCC 8739 6064698 YP_001725781.1 CDS EcolC_2826 NC_010468.1 3092750 3093217 R Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR complement(3092750..3093217) Escherichia coli ATCC 8739 6065085 YP_001725782.1 CDS EcolC_2827 NC_010468.1 3093403 3093531 D KEGG: sec:SC0831 hypothetical protein; hypothetical protein 3093403..3093531 Escherichia coli ATCC 8739 6065090 YP_001725783.1 CDS EcolC_2828 NC_010468.1 3093803 3095386 D PFAM: sulfatase; KEGG: sbo:SBO_0706 putative enzyme; sulfatase 3093803..3095386 Escherichia coli ATCC 8739 6065091 YP_001725784.1 CDS ompX NC_010468.1 3095435 3095950 R OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X complement(3095435..3095950) Escherichia coli ATCC 8739 6065093 YP_001725785.1 CDS EcolC_2830 NC_010468.1 3096303 3097190 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_0793 putative transmembrane subunit; threonine and homoserine efflux system 3096303..3097190 Escherichia coli ATCC 8739 6065094 YP_001725786.1 CDS EcolC_2831 NC_010468.1 3097489 3097992 D binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 3097489..3097992 Escherichia coli ATCC 8739 6065101 YP_001725787.1 CDS glnH NC_010468.1 3098396 3099142 D similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 3098396..3099142 Escherichia coli ATCC 8739 6065103 YP_001725788.1 CDS glnP NC_010468.1 3099281 3099940 D similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 3099281..3099940 Escherichia coli ATCC 8739 6065108 YP_001725789.1 CDS glnQ NC_010468.1 3099937 3100659 D similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 3099937..3100659 Escherichia coli ATCC 8739 6065113 YP_001725790.1 CDS EcolC_2835 NC_010468.1 3100920 3103145 D PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0788 putative transport protein; hypothetical protein 3100920..3103145 Escherichia coli ATCC 8739 6065118 YP_001725791.1 CDS EcolC_2836 NC_010468.1 3103142 3104068 R PFAM: protein of unknown function DUF890; KEGG: sbo:SBO_0697 hypothetical protein; putative SAM-dependent methyltransferase complement(3103142..3104068) Escherichia coli ATCC 8739 6065130 YP_001725792.1 CDS EcolC_2837 NC_010468.1 3104344 3104604 D PFAM: protein of unknown function DUF1471; KEGG: ssn:SSON_0786 hypothetical protein; hypothetical protein 3104344..3104604 Escherichia coli ATCC 8739 6065131 YP_001725793.1 CDS EcolC_2838 NC_010468.1 3104869 3107151 D Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 3104869..3107151 Escherichia coli ATCC 8739 6065134 YP_001725794.1 CDS EcolC_2839 NC_010468.1 3107193 3107870 D PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: sbo:SBO_0692 putative enzyme; putative hydroxylase 3107193..3107870 Escherichia coli ATCC 8739 6064977 YP_001725795.1 CDS EcolC_2840 NC_010468.1 3107944 3108210 D PFAM: zinc finger DksA/TraR C4-type; KEGG: ssn:SSON_0782 hypothetical protein; hypothetical protein 3107944..3108210 Escherichia coli ATCC 8739 6065138 YP_001725796.1 CDS EcolC_2841 NC_010468.1 3108475 3108735 D PFAM: protein of unknown function DUF1471; KEGG: sfv:SFV_0785 hypothetical protein; hypothetical protein 3108475..3108735 Escherichia coli ATCC 8739 6065142 YP_001725797.1 CDS EcolC_2842 NC_010468.1 3108964 3110049 R PFAM: Malate/L-lactate dehydrogenase; KEGG: ssn:SSON_0780 putative dehydrogenase; hypothetical protein complement(3108964..3110049) Escherichia coli ATCC 8739 6065144 YP_001725798.1 CDS EcolC_2843 NC_010468.1 3110190 3111152 R PFAM: glycosyl transferase family 3; KEGG: sbo:SBO_0688 putative enzyme; glycosyl transferase family protein complement(3110190..3111152) Escherichia coli ATCC 8739 6065145 YP_001725799.1 CDS dinG NC_010468.1 3111180 3113330 R helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG complement(3111180..3113330) Escherichia coli ATCC 8739 6065147 YP_001725800.1 CDS EcolC_2845 NC_010468.1 3113483 3113932 D PFAM: conserved hypothetical protein; KEGG: sbo:SBO_0686 hypothetical protein; hypothetical protein 3113483..3113932 Escherichia coli ATCC 8739 6064940 YP_001725801.1 CDS EcolC_2846 NC_010468.1 3114164 3115528 R this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE complement(3114164..3115528) Escherichia coli ATCC 8739 6065153 YP_001725802.1 CDS EcolC_2847 NC_010468.1 3115757 3116428 D PFAM: regulatory protein TetR; Transcriptional regulator TetR; KEGG: sdy:SDY_0807 putative transcriptional regulator; putative DNA-binding transcriptional regulator 3115757..3116428 Escherichia coli ATCC 8739 6065154 YP_001725803.1 CDS EcolC_2848 NC_010468.1 3116431 3117426 D PFAM: secretion protein HlyD family protein; KEGG: sfv:SFV_0778 hypothetical protein; hypothetical protein 3116431..3117426 Escherichia coli ATCC 8739 6065162 YP_001725804.1 CDS EcolC_2849 NC_010468.1 3117419 3119155 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfl:SF0744 putative ATP-binding component of a transport system; ABC transporter-like protein 3117419..3119155 Escherichia coli ATCC 8739 6065167 YP_001725805.1 CDS EcolC_2850 NC_010468.1 3119148 3120281 D PFAM: ABC-2 type transporter; KEGG: ssn:SSON_0772 hypothetical protein; ABC-2 type transporter 3119148..3120281 Escherichia coli ATCC 8739 6065169 YP_001725806.1 CDS EcolC_2851 NC_010468.1 3120292 3121398 D PFAM: ABC-2 type transporter; KEGG: ssn:SSON_0771 hypothetical protein; ABC-2 type transporter 3120292..3121398 Escherichia coli ATCC 8739 6065176 YP_001725807.1 CDS EcolC_2852 NC_010468.1 3121360 3121770 R KEGG: sbo:SBO_0679 hypothetical protein; hypothetical protein complement(3121360..3121770) Escherichia coli ATCC 8739 6065180 YP_001725808.1 CDS EcolC_2853 NC_010468.1 3121903 3122664 D PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ssn:SSON_0769 hypothetical protein; endonuclease/exonuclease/phosphatase 3121903..3122664 Escherichia coli ATCC 8739 6065183 YP_001725809.1 CDS EcolC_2854 NC_010468.1 3122661 3123902 D KEGG: ssn:SSON_0768 putative synthetase; cardiolipin synthase 2 3122661..3123902 Escherichia coli ATCC 8739 6065196 YP_001725810.1 CDS EcolC_2855 NC_010468.1 3123902 3124858 D KEGG: sfv:SFV_0771 hypothetical protein; hypothetical protein 3123902..3124858 Escherichia coli ATCC 8739 6065197 YP_001725811.1 CDS EcolC_2856 NC_010468.1 3124894 3125607 R PFAM: protein of unknown function UPF0005; KEGG: sfv:SFV_0770 hypothetical protein; hypothetical protein complement(3124894..3125607) Escherichia coli ATCC 8739 6065199 YP_001725812.1 CDS EcolC_2857 NC_010468.1 3125812 3126516 R PFAM: protein of unknown function UPF0005; KEGG: sbo:SBO_0673 hypothetical protein; hypothetical protein complement(3125812..3126516) Escherichia coli ATCC 8739 6065207 YP_001725813.1 CDS moaE NC_010468.1 3126654 3127106 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE complement(3126654..3127106) Escherichia coli ATCC 8739 6065211 YP_001725814.1 CDS moaD NC_010468.1 3127108 3127353 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit complement(3127108..3127353) Escherichia coli ATCC 8739 6065220 YP_001725815.1 CDS moaC NC_010468.1 3127346 3127831 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(3127346..3127831) Escherichia coli ATCC 8739 6065223 YP_001725816.1 CDS EcolC_2861 NC_010468.1 3127834 3128346 R TIGRFAM: molybdenum cofactor synthesis domain protein; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: sbo:SBO_0669 molybdopterin biosynthesis, protein B; molybdenum cofactor biosynthesis protein B complement(3127834..3128346) Escherichia coli ATCC 8739 6065228 YP_001725817.1 CDS moaA NC_010468.1 3128368 3129390 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(3128368..3129390) Escherichia coli ATCC 8739 6065234 YP_001725818.1 CDS EcolC_2863 NC_010468.1 3129754 3130662 D PFAM: protein of unknown function UPF0052 and CofD; KEGG: sbo:SBO_0667 putative structural protein; hypothetical protein 3129754..3130662 Escherichia coli ATCC 8739 6065239 YP_001725819.1 CDS EcolC_2864 NC_010468.1 3130854 3132875 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(3130854..3132875) Escherichia coli ATCC 8739 6065246 YP_001725820.1 CDS bioD NC_010468.1 3133454 3134131 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(3133454..3134131) Escherichia coli ATCC 8739 6065247 YP_001725821.1 CDS EcolC_2866 NC_010468.1 3134124 3134879 R putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC complement(3134124..3134879) Escherichia coli ATCC 8739 6065251 YP_001725822.1 CDS EcolC_2867 NC_010468.1 3134866 3136020 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(3134866..3136020) Escherichia coli ATCC 8739 6065252 YP_001725823.1 CDS EcolC_2868 NC_010468.1 3136017 3137057 R KEGG: ssn:SSON_0754 biotin synthesis; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; biotin synthase complement(3136017..3137057) Escherichia coli ATCC 8739 6065110 YP_001725824.1 CDS EcolC_2869 NC_010468.1 3137201 3138433 D catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 3137201..3138433 Escherichia coli ATCC 8739 6065257 YP_001725825.1 CDS EcolC_2870 NC_010468.1 3138492 3138968 D YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein 3138492..3138968 Escherichia coli ATCC 8739 6065191 YP_001725826.1 CDS EcolC_2872 NC_010468.1 3139730 3140427 R PFAM: Insertion element protein; KEGG: sdy:SDY_4618 IS1 ORF1; insertion element protein complement(join(3139730..3140173,3140173..3140427)) Escherichia coli ATCC 8739 6065277 YP_001725827.1 CDS EcolC_2873 NC_010468.1 3140516 3140680 D PFAM: Lambda phage regulatory protein CIII; KEGG: spt:SPA2420 hypothetical protein; lambda phage regulatory protein CIII 3140516..3140680 Escherichia coli ATCC 8739 6065280 YP_001725828.1 CDS EcolC_2874 NC_010468.1 3140523 3140792 D PFAM: lambda Kil; lambda Kil 3140523..3140792 Escherichia coli ATCC 8739 6065281 YP_001725829.1 CDS EcolC_2875 NC_010468.1 3140868 3141164 D PFAM: Host-nuclease inhibitor Gam; KEGG: sdy:SDY_1384 putative host-nuclease inhibitor protein Gam; host-nuclease inhibitor Gam 3140868..3141164 Escherichia coli ATCC 8739 6065285 YP_001725830.1 CDS EcolC_2876 NC_010468.1 3141170 3141955 D TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: stt:t1923 bacteriophage recombination protein; phage recombination protein Bet 3141170..3141955 Escherichia coli ATCC 8739 6065288 YP_001725831.1 CDS EcolC_2877 NC_010468.1 3141952 3142632 D PFAM: Exonuclease, phage-type; KEGG: sdy:SDY_1382 exonuclease; exodeoxyribonuclease 3141952..3142632 Escherichia coli ATCC 8739 6065292 YP_001725832.1 CDS EcolC_2878 NC_010468.1 3142629 3142811 D PFAM: protein of unknown function DUF1317; hypothetical protein 3142629..3142811 Escherichia coli ATCC 8739 6065294 YP_001725833.1 CDS EcolC_2879 NC_010468.1 3142784 3142975 D PFAM: protein of unknown function DUF1382; hypothetical protein 3142784..3142975 Escherichia coli ATCC 8739 6065300 YP_001725834.1 CDS EcolC_2880 NC_010468.1 3142986 3143267 D hypothetical protein 3142986..3143267 Escherichia coli ATCC 8739 6065303 YP_001725835.1 CDS EcolC_2881 NC_010468.1 3143366 3143587 D TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: hit:NTHI1878 DnaK suppressor protein, bacteriophage PSP3 GP34 homolog; TraR/DksA family transcriptional regulator 3143366..3143587 Escherichia coli ATCC 8739 6065149 YP_001725836.1 CDS EcolC_2882 NC_010468.1 3143584 3143835 D KEGG: sfv:SFV_0261 putative bacteriophage protein; putative bacteriophage protein 3143584..3143835 Escherichia coli ATCC 8739 6065306 YP_001725837.1 CDS EcolC_2883 NC_010468.1 3144082 3144779 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(3144082..3144525,3144525..3144779)) Escherichia coli ATCC 8739 6065317 YP_001725838.1 CDS EcolC_2884 NC_010468.1 3144892 3145506 D KEGG: mes:Meso_1109 hypothetical protein; hypothetical protein 3144892..3145506 Escherichia coli ATCC 8739 6065321 YP_001725839.1 CDS EcolC_2885 NC_010468.1 3145800 3146138 D KEGG: yps:YPTB1765 putative GP46 [bacteriophage N15] pir||T13133 protein GP46-...; Contains selenocysteine; hypothetical protein 3145800..3146138 Escherichia coli ATCC 8739 6064677 YP_001725840.1 CDS EcolC_2886 NC_010468.1 3146167 3146595 D KEGG: cps:CPS_0896 hypothetical protein; hypothetical protein 3146167..3146595 Escherichia coli ATCC 8739 6065325 YP_001725841.1 CDS EcolC_2887 NC_010468.1 3146678 3146845 D hypothetical protein 3146678..3146845 Escherichia coli ATCC 8739 6065326 YP_001725842.1 CDS EcolC_2888 NC_010468.1 3146885 3147103 D PFAM: Excisionase domain protein; excisionase domain-containing protein 3146885..3147103 Escherichia coli ATCC 8739 6065329 YP_001725843.1 CDS EcolC_2889 NC_010468.1 3147081 3148151 D PFAM: integrase family protein; integrase domain protein SAM domain protein; lambda integrase; KEGG: ssn:SSON_0746 putative integrase fragment; lambda integrase 3147081..3148151 Escherichia coli ATCC 8739 6065335 YP_001725844.1 CDS EcolC_2890 NC_010468.1 3148286 3149569 D outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase 3148286..3149569 Escherichia coli ATCC 8739 6065080 YP_001725845.1 CDS EcolC_2891 NC_010468.1 3149803 3152064 R PFAM: aconitate hydratase domain protein; KEGG: sbo:SBO_0658 putative enzyme; hypothetical protein complement(3149803..3152064) Escherichia coli ATCC 8739 6065339 YP_001725846.1 CDS EcolC_2892 NC_010468.1 3152247 3153680 R TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: sfv:SFV_0753 putative membrane pump protein; anion transporter complement(3152247..3153680) Escherichia coli ATCC 8739 6065341 YP_001725847.1 CDS EcolC_2893 NC_010468.1 3153756 3154808 R PFAM: protein of unknown function DUF453; KEGG: sfv:SFV_0752 hypothetical protein; hypothetical protein complement(3153756..3154808) Escherichia coli ATCC 8739 6065351 YP_001725848.1 CDS EcolC_2894 NC_010468.1 3154992 3155945 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_0742 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 3154992..3155945 Escherichia coli ATCC 8739 6065357 YP_001725849.1 CDS EcolC_2895 NC_010468.1 3155986 3156981 R catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase complement(3155986..3156981) Escherichia coli ATCC 8739 6065358 YP_001725850.1 CDS EcolC_2896 NC_010468.1 3157136 3157954 D YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 3157136..3157954 Escherichia coli ATCC 8739 6065360 YP_001725851.1 CDS modC NC_010468.1 3157955 3159013 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(3157955..3159013) Escherichia coli ATCC 8739 6065363 YP_001725852.1 CDS modB NC_010468.1 3159016 3159705 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease complement(3159016..3159705) Escherichia coli ATCC 8739 6065364 YP_001725853.1 CDS modA NC_010468.1 3159705 3160478 R with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein complement(3159705..3160478) Escherichia coli ATCC 8739 6065365 YP_001725854.1 CDS EcolC_2900 NC_010468.1 3160645 3160794 R KEGG: sdy:SDY_0709 hypothetical protein; hypothetical protein complement(3160645..3160794) Escherichia coli ATCC 8739 6065369 YP_001725855.1 CDS EcolC_2901 NC_010468.1 3160923 3161711 D represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 3160923..3161711 Escherichia coli ATCC 8739 6065373 YP_001725856.1 CDS EcolC_2902 NC_010468.1 3161779 3163251 D contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 3161779..3163251 Escherichia coli ATCC 8739 6065376 YP_001725857.1 CDS EcolC_2903 NC_010468.1 3163512 3164528 D TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ssn:SSON_0711 UDP-galactose-4-epimerase; UDP-galactose-4-epimerase 3163512..3164528 Escherichia coli ATCC 8739 6065378 YP_001725858.1 CDS EcolC_2904 NC_010468.1 3164538 3165584 D catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 3164538..3165584 Escherichia coli ATCC 8739 6065383 YP_001725859.1 CDS EcolC_2905 NC_010468.1 3165588 3166736 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 3165588..3166736 Escherichia coli ATCC 8739 6065384 YP_001725860.1 CDS galM NC_010468.1 3166730 3167770 D catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 3166730..3167770 Escherichia coli ATCC 8739 6065388 YP_001725861.1 CDS gpmA NC_010468.1 3167972 3168724 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 3167972..3168724 Escherichia coli ATCC 8739 6065403 YP_001725862.1 CDS EcolC_2908 NC_010468.1 3168882 3169934 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3168882..3169934) Escherichia coli ATCC 8739 6065406 YP_001725863.1 CDS EcolC_2909 NC_010468.1 3170250 3170630 D KEGG: sfv:SFV_0587 putative homeobox protein; putative homeobox protein 3170250..3170630 Escherichia coli ATCC 8739 6065409 YP_001725864.1 CDS EcolC_2910 NC_010468.1 3170744 3171685 D involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 3170744..3171685 Escherichia coli ATCC 8739 6065419 YP_001725865.1 CDS EcolC_2911 NC_010468.1 3171682 3172401 R TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: ssn:SSON_0703 required for NMN transport; nicotinamide mononucleotide transporter PnuC complement(3171682..3172401) Escherichia coli ATCC 8739 6064996 YP_001725866.1 CDS EcolC_2912 NC_010468.1 3172439 3173482 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(3172439..3173482) Escherichia coli ATCC 8739 6064761 YP_001725867.1 CDS EcolC_2913 NC_010468.1 3174925 3175716 R periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF complement(3174925..3175716) Escherichia coli ATCC 8739 6065469 YP_001725868.1 CDS EcolC_2914 NC_010468.1 3175726 3176247 R TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: sbo:SBO_0600 peptidoglycan-associated lipoprotein; peptidoglycan-associated outer membrane lipoprotein complement(3175726..3176247) Escherichia coli ATCC 8739 6065471 YP_001725869.1 CDS tolB NC_010468.1 3176282 3177574 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(3176282..3177574) Escherichia coli ATCC 8739 6065480 YP_001725870.1 CDS tolA NC_010468.1 3177707 3178978 R inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA complement(3177707..3178978) Escherichia coli ATCC 8739 6065482 YP_001725871.1 CDS EcolC_2917 NC_010468.1 3179043 3179471 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR complement(3179043..3179471) Escherichia coli ATCC 8739 6065485 YP_001725872.1 CDS EcolC_2918 NC_010468.1 3179475 3180158 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ complement(3179475..3180158) Escherichia coli ATCC 8739 6065492 YP_001725873.1 CDS EcolC_2919 NC_010468.1 3180164 3180568 R catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC complement(3180164..3180568) Escherichia coli ATCC 8739 6065496 YP_001725874.1 CDS EcolC_2920 NC_010468.1 3180718 3181011 R TIGRFAM: cyd operon protein YbgE; PFAM: Cyd operon protein YbgE; KEGG: sdy:SDY_0683 hypothetical protein; hypothetical protein complement(3180718..3181011) Escherichia coli ATCC 8739 6065499 YP_001725875.1 CDS EcolC_2921 NC_010468.1 3181011 3181124 R TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sdy:SDY_0682 putative outer membrane lipoprotein; cyd operon protein YbgT complement(3181011..3181124) Escherichia coli ATCC 8739 6065506 YP_001725876.1 CDS EcolC_2922 NC_010468.1 3181139 3182278 R KEGG: ssn:SSON_0686 cytochrome d terminal oxidase polypeptide subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II complement(3181139..3182278) Escherichia coli ATCC 8739 6065507 YP_001725877.1 CDS EcolC_2923 NC_010468.1 3182294 3183862 R PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sbo:SBO_0592 cytochrome d terminal oxidase, polypeptide subunit I; cytochrome bd ubiquinol oxidase subunit I complement(3182294..3183862) Escherichia coli ATCC 8739 6065510 YP_001725878.1 CDS EcolC_2924 NC_010468.1 3184709 3187342 R PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; KEGG: sfv:SFV_0604 putative sugar hydrolase; alpha-mannosidase complement(3184709..3187342) Escherichia coli ATCC 8739 6065513 YP_001725879.1 CDS EcolC_2925 NC_010468.1 3187360 3189276 R involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC complement(3187360..3189276) Escherichia coli ATCC 8739 6065515 YP_001725880.1 CDS EcolC_2926 NC_010468.1 3189445 3190167 D regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 3189445..3190167 Escherichia coli ATCC 8739 6065519 YP_001725881.1 CDS EcolC_2927 NC_010468.1 3190271 3191140 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(3190271..3191140) Escherichia coli ATCC 8739 6065521 YP_001725882.1 CDS sucC NC_010468.1 3191140 3192306 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(3191140..3192306) Escherichia coli ATCC 8739 6065523 YP_001725883.1 CDS EcolC_2929 NC_010468.1 3192581 3193798 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(3192581..3193798) Escherichia coli ATCC 8739 6065524 YP_001725884.1 CDS sucA NC_010468.1 3193813 3196614 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(3193813..3196614) Escherichia coli ATCC 8739 6065526 YP_001725885.1 CDS sdhB NC_010468.1 3196815 3197531 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(3196815..3197531) Escherichia coli ATCC 8739 6065532 YP_001725886.1 CDS sdhA NC_010468.1 3197547 3199313 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(3197547..3199313) Escherichia coli ATCC 8739 6065372 YP_001725887.1 CDS sdhD NC_010468.1 3199313 3199660 R TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: sdy:SDY_0660 succinate dehydrogenase, hydrophobic subunit; succinate dehydrogenase cytochrome b556 small membrane subunit complement(3199313..3199660) Escherichia coli ATCC 8739 6065462 YP_001725888.1 CDS sdhC NC_010468.1 3199654 3200058 R TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: sfx:S0589 succinate dehydrogenase, cytochrome b556; succinate dehydrogenase cytochrome b556 large membrane subunit complement(3199654..3200058) Escherichia coli ATCC 8739 6065538 YP_001725889.1 CDS gltA NC_010468.1 3200752 3202035 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 3200752..3202035 Escherichia coli ATCC 8739 6064981 YP_001725890.1 CDS EcolC_2936 NC_010468.1 3202424 3202990 D PFAM: Fimbrial protein; KEGG: ssn:SSON_0670 putative fimbrial-like protein; fimbrial protein 3202424..3202990 Escherichia coli ATCC 8739 6065546 YP_001725891.1 CDS EcolC_2937 NC_010468.1 3203041 3205500 D PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfx:S0592 putative outer membrane protein; fimbrial biogenesis outer membrane usher protein 3203041..3205500 Escherichia coli ATCC 8739 6065552 YP_001725892.1 CDS EcolC_2938 NC_010468.1 3205515 3206246 D PFAM: pili assembly chaperone; KEGG: ssn:SSON_0668 putative chaperone; pili assembly chaperone 3205515..3206246 Escherichia coli ATCC 8739 6065556 YP_001725893.1 CDS EcolC_2939 NC_010468.1 3206243 3207304 D KEGG: ssn:SSON_0667 hypothetical protein; hypothetical protein 3206243..3207304 Escherichia coli ATCC 8739 6065558 YP_001725894.1 CDS EcolC_2940 NC_010468.1 3207456 3208502 D TIGRFAM: membrane protein AbrB duplication; PFAM: putative ammonia monooxygenase; KEGG: ssn:SSON_0666 putative transport protein; membrane protein AbrB 3207456..3208502 Escherichia coli ATCC 8739 6065559 YP_001725895.1 CDS EcolC_2941 NC_010468.1 3208499 3209290 R 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII complement(3208499..3209290) Escherichia coli ATCC 8739 6065572 YP_001725896.1 CDS EcolC_2942 NC_010468.1 3209326 3210060 R PFAM: LamB/YcsF family protein; KEGG: sbo:SBO_0572 putative lactam utilization protein; LamB/YcsF family protein complement(3209326..3210060) Escherichia coli ATCC 8739 6065582 YP_001725897.1 CDS EcolC_2943 NC_010468.1 3210050 3210982 R TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: sbo:SBO_0571 putative carboxylase; urea amidolyase-like protein complement(3210050..3210982) Escherichia coli ATCC 8739 6065584 YP_001725898.1 CDS EcolC_2944 NC_010468.1 3210976 3211632 R PFAM: Allophanate hydrolase subunit 1; KEGG: ssn:SSON_0662 putative carboxylase; allophanate hydrolase subunit 1 complement(3210976..3211632) Escherichia coli ATCC 8739 6065598 YP_001725899.1 CDS EcolC_2945 NC_010468.1 3211655 3212398 R PFAM: protein of unknown function DUF34; KEGG: sbo:SBO_0569 hypothetical protein; putative hydrolase-oxidase complement(3211655..3212398) Escherichia coli ATCC 8739 6065600 YP_001725900.1 CDS EcolC_2946 NC_010468.1 3212669 3214150 D KEGG: sfx:S0601 putative transport protein; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; amino acid/peptide transporter 3212669..3214150 Escherichia coli ATCC 8739 6065618 YP_001725901.1 CDS EcolC_2947 NC_010468.1 3214192 3215610 R UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase complement(3214192..3215610) Escherichia coli ATCC 8739 6065619 YP_001725902.1 CDS EcolC_2948 NC_010468.1 3215607 3216116 R PFAM: Protein of unknown function DUF1722; KEGG: sfv:SFV_0628 hypothetical protein; hypothetical protein complement(3215607..3216116) Escherichia coli ATCC 8739 6065627 YP_001725903.1 CDS EcolC_2949 NC_010468.1 3216264 3217025 R PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein complement(3216264..3217025) Escherichia coli ATCC 8739 6065628 YP_001725904.1 CDS EcolC_2950 NC_010468.1 3217156 3218292 R PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein complement(3217156..3218292) Escherichia coli ATCC 8739 6064758 YP_001725905.1 CDS EcolC_2952 NC_010468.1 3220082 3220651 R hypothetical protein complement(3220082..3220651) Escherichia coli ATCC 8739 6065644 YP_001725906.1 CDS EcolC_2953 NC_010468.1 3220648 3222081 R PFAM: RHS protein; YD repeat-containing protein; KEGG: ssn:SSON_0655 RhsA protein in rhs element; RHS protein complement(3220648..3222081) Escherichia coli ATCC 8739 6065650 YP_001725907.1 CDS EcolC_2954 NC_010468.1 3222199 3222525 R hypothetical protein complement(3222199..3222525) Escherichia coli ATCC 8739 6065659 YP_001725908.1 CDS EcolC_2955 NC_010468.1 3222525 3226718 R TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(3222525..3226718) Escherichia coli ATCC 8739 6065660 YP_001725909.1 CDS EcolC_2956 NC_010468.1 3226961 3227167 R KEGG: sdy:SDY_0635 hypothetical protein; hypothetical protein complement(3226961..3227167) Escherichia coli ATCC 8739 6065664 YP_001725910.1 CDS kdpF NC_010468.1 3227480 3227569 D one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase F 3227480..3227569 Escherichia coli ATCC 8739 6065672 YP_001725911.1 CDS EcolC_2958 NC_010468.1 3227569 3229242 D catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase A 3227569..3229242 Escherichia coli ATCC 8739 6065684 YP_001725912.1 CDS EcolC_2959 NC_010468.1 3229265 3231313 D One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase B 3229265..3231313 Escherichia coli ATCC 8739 6065688 YP_001725913.1 CDS EcolC_2960 NC_010468.1 3231322 3231894 D One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase C 3231322..3231894 Escherichia coli ATCC 8739 6065693 YP_001725914.1 CDS EcolC_2961 NC_010468.1 3231887 3234574 D sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 3231887..3234574 Escherichia coli ATCC 8739 6065697 YP_001725915.1 CDS EcolC_2962 NC_010468.1 3234571 3235248 D response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 3234571..3235248 Escherichia coli ATCC 8739 6065699 YP_001725916.1 CDS EcolC_2963 NC_010468.1 3235844 3238042 D PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sbo:SBO_0554 ornithine decarboxylase isozyme, inducible; ornithine decarboxylase 3235844..3238042 Escherichia coli ATCC 8739 6065700 YP_001725917.1 CDS potE NC_010468.1 3238039 3239358 D catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 3238039..3239358 Escherichia coli ATCC 8739 6065009 YP_001725918.1 CDS EcolC_2966 NC_010468.1 3239707 3240357 D KEGG: sbo:SBO_0552 hypothetical protein; hypothetical protein 3239707..3240357 Escherichia coli ATCC 8739 6065718 YP_001725919.1 CDS EcolC_2967 NC_010468.1 3240398 3240892 R KEGG: sbo:SBO_0551 putative pectinase; putative pectinase complement(3240398..3240892) Escherichia coli ATCC 8739 6065719 YP_001725920.1 CDS EcolC_2968 NC_010468.1 3241107 3242747 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(3241107..3242747) Escherichia coli ATCC 8739 6065727 YP_001725921.1 CDS EcolC_2969 NC_010468.1 3242773 3243318 R negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA complement(3242773..3243318) Escherichia coli ATCC 8739 6065728 YP_001725922.1 CDS EcolC_2970 NC_010468.1 3243503 3244267 D PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sbo:SBO_0548 hypothetical protein; hypothetical protein 3243503..3244267 Escherichia coli ATCC 8739 6065735 YP_001725923.1 CDS EcolC_2971 NC_010468.1 3244338 3244700 D PFAM: CopG domain protein DNA-binding domain protein; KEGG: sdy:SDY_0625 hypothetical protein; LexA regulated protein 3244338..3244700 Escherichia coli ATCC 8739 6065736 YP_001725924.1 CDS EcolC_2972 NC_010468.1 3244840 3245370 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 3244840..3245370 Escherichia coli ATCC 8739 6065157 YP_001725925.1 CDS fur NC_010468.1 3245659 3246105 D negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 3245659..3246105 Escherichia coli ATCC 8739 6065743 YP_001725926.1 CDS EcolC_2974 NC_010468.1 3246189 3246515 R KEGG: sfl:SF0611 hypothetical protein; hypothetical protein complement(3246189..3246515) Escherichia coli ATCC 8739 6065255 YP_001725927.1 CDS EcolC_2975 NC_010468.1 3246565 3247971 R PFAM: outer membrane porin; KEGG: sfx:S0623 hypothetical protein; outer membrane porin complement(3246565..3247971) Escherichia coli ATCC 8739 6065746 YP_001725928.1 CDS EcolC_2976 NC_010468.1 3248548 3250212 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(3248548..3250212) Escherichia coli ATCC 8739 6065680 YP_001725929.1 CDS EcolC_2977 NC_010468.1 3250480 3252426 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC complement(3250480..3252426) Escherichia coli ATCC 8739 6065543 YP_001725930.1 CDS nagB NC_010468.1 3252759 3253559 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 3252759..3253559 Escherichia coli ATCC 8739 6065756 YP_001725931.1 CDS nagA NC_010468.1 3253619 3254767 D catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 3253619..3254767 Escherichia coli ATCC 8739 6065340 YP_001725932.1 CDS EcolC_2980 NC_010468.1 3254776 3255996 D PFAM: ROK family protein; KEGG: sdy:SDY_0610 transcriptional repressor of N-acetylglucosamine operon; ROK family protein 3254776..3255996 Escherichia coli ATCC 8739 6065762 YP_001725933.1 CDS EcolC_2981 NC_010468.1 3256044 3256796 D TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdy:SDY_0609 N-acetylglucosamine metabolism; UMP phosphatase 3256044..3256796 Escherichia coli ATCC 8739 6065533 YP_001725934.1 CDS asnB NC_010468.1 3257193 3258857 D functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 3257193..3258857 Escherichia coli ATCC 8739 6065771 YP_001725935.1 CDS ubiF NC_010468.1 3260094 3261269 R catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(3260094..3261269) Escherichia coli ATCC 8739 6065838 YP_001725936.1 CDS EcolC_2984 NC_010468.1 3261415 3262839 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 3261415..3262839 Escherichia coli ATCC 8739 6065844 YP_001725937.1 CDS EcolC_2985 NC_010468.1 3262953 3264032 D PFAM: PhoH family protein; KEGG: sdy:SDY_0596 putative ATP-binding protein in pho regulon; PhoH family protein 3262953..3264032 Escherichia coli ATCC 8739 6065846 YP_001725938.1 CDS EcolC_2986 NC_010468.1 3264029 3264496 D PFAM: protein of unknown function UPF0054; KEGG: sbo:SBO_0523 hypothetical protein; putative metalloprotease 3264029..3264496 Escherichia coli ATCC 8739 6064922 YP_001725939.1 CDS EcolC_2987 NC_010468.1 3264586 3265464 D PFAM: CBS domain containing protein; transporter-associated region; KEGG: sdy:SDY_0594 putative transport protein; transporter-associated protein 3264586..3265464 Escherichia coli ATCC 8739 6065848 YP_001725940.1 CDS lnt NC_010468.1 3265489 3267027 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 3265489..3267027 Escherichia coli ATCC 8739 6065850 YP_001725941.1 CDS EcolC_2989 NC_010468.1 3267154 3269031 R TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: Rhomboid family protein; KEGG: ssn:SSON_0610 hypothetical protein; hypothetical protein complement(3267154..3269031) Escherichia coli ATCC 8739 6065853 YP_001725942.1 CDS EcolC_2990 NC_010468.1 3269486 3270394 D PFAM: extracellular solute-binding protein family 3; KEGG: sdy:SDY_0592 putative periplasmic binding transport protein; glutamate and aspartate transporter subunit 3269486..3270394 Escherichia coli ATCC 8739 6065875 YP_001725943.1 CDS EcolC_2991 NC_010468.1 3270564 3271304 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_0672 glutamate/aspartate transport system permease; polar amino acid ABC transporter inner membrane protein 3270564..3271304 Escherichia coli ATCC 8739 6065881 YP_001725944.1 CDS EcolC_2992 NC_010468.1 3271304 3271978 D TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfx:S0650 glutamate/aspartate transport system permease; polar amino acid ABC transporter inner membrane protein 3271304..3271978 Escherichia coli ATCC 8739 6065884 YP_001725945.1 CDS EcolC_2993 NC_010468.1 3271978 3272703 D PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_0606 ATP-binding protein of glutamate/aspartate transport system; ABC transporter-like protein 3271978..3272703 Escherichia coli ATCC 8739 6065890 YP_001725946.1 CDS rihA NC_010468.1 3272821 3273756 D Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 3272821..3273756 Escherichia coli ATCC 8739 6065891 YP_001725947.1 CDS EcolC_2995 NC_010468.1 3273840 3275510 D PFAM: Heat shock protein 70; KEGG: ssn:SSON_0604 putative DnaK protein; 2-alkenal reductase 3273840..3275510 Escherichia coli ATCC 8739 6065896 YP_001725948.1 CDS EcolC_2996 NC_010468.1 3275570 3277021 R PFAM: heat shock protein DnaJ domain protein; KEGG: ssn:SSON_0603 hypothetical protein; heat shock protein DnaJ domain-containing protein complement(3275570..3277021) Escherichia coli ATCC 8739 6065904 YP_001725949.1 CDS EcolC_2997 NC_010468.1 3277018 3277725 R PFAM: protein of unknown function DUF1266; KEGG: sfv:SFV_0678 putative tRNA ligase; hypothetical protein complement(3277018..3277725) Escherichia coli ATCC 8739 6065913 YP_001725950.1 CDS EcolC_2998 NC_010468.1 3277827 3278381 D PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfv:SFV_0679 hypothetical protein; Sel1 domain-containing protein 3277827..3278381 Escherichia coli ATCC 8739 6065923 YP_001725951.1 CDS EcolC_2999 NC_010468.1 3278391 3279818 R PFAM: heat shock protein DnaJ domain protein; KEGG: sbo:SBO_0510 putative enzyme of polynucleotide modification; heat shock protein DnaJ domain-containing protein complement(3278391..3279818) Escherichia coli ATCC 8739 6065931 YP_001725952.1 CDS EcolC_3000 NC_010468.1 3279815 3280522 R PFAM: protein of unknown function DUF1266; KEGG: sbo:SBO_0509 hypothetical protein; hypothetical protein complement(3279815..3280522) Escherichia coli ATCC 8739 6065934 YP_001725953.1 CDS EcolC_3001 NC_010468.1 3280686 3281663 D PFAM: Sel1 domain protein repeat-containing protein; KEGG: ssn:SSON_0598 hypothetical protein; Sel1 domain-containing protein 3280686..3281663 Escherichia coli ATCC 8739 6065940 YP_001725954.1 CDS EcolC_3002 NC_010468.1 3281733 3282215 R PFAM: protein of unknown function DUF1451; KEGG: sdy:SDY_0567 putative alpha helical protein; hypothetical protein complement(3281733..3282215) Escherichia coli ATCC 8739 6065273 YP_001725955.1 CDS leuS NC_010468.1 3282451 3285033 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 3282451..3285033 Escherichia coli ATCC 8739 6065945 YP_001725956.1 CDS EcolC_3004 NC_010468.1 3285048 3285629 D rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 3285048..3285629 Escherichia coli ATCC 8739 6065946 YP_001725957.1 CDS holA NC_010468.1 3285629 3286660 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 3285629..3286660 Escherichia coli ATCC 8739 6065950 YP_001725958.1 CDS nadD NC_010468.1 3286662 3287303 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 3286662..3287303 Escherichia coli ATCC 8739 6065953 YP_001725959.1 CDS EcolC_3007 NC_010468.1 3287327 3287938 D TIGRFAM: alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase; KEGG: sfv:SFV_0688 PhpB; alpha-ribazole phosphatase 3287327..3287938 Escherichia coli ATCC 8739 6065968 YP_001725960.1 CDS EcolC_3008 NC_010468.1 3288198 3288515 D TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: sfv:SFV_0689 hypothetical protein; hypothetical protein 3288198..3288515 Escherichia coli ATCC 8739 6065969 YP_001725961.1 CDS EcolC_3009 NC_010468.1 3288519 3288986 D SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 3288519..3288986 Escherichia coli ATCC 8739 6065971 YP_001725962.1 CDS EcolC_3010 NC_010468.1 3289017 3290918 D KEGG: sfv:SFV_0691 penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; penicillin-binding protein 2 3289017..3290918 Escherichia coli ATCC 8739 6065972 YP_001725963.1 CDS EcolC_3011 NC_010468.1 3290921 3292033 D TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: sbo:SBO_0498 rod shape-determining membrane protein; cell wall shape-determining protein 3290921..3292033 Escherichia coli ATCC 8739 6065979 YP_001725964.1 CDS EcolC_3012 NC_010468.1 3292044 3293132 D TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: ssn:SSON_0587 minor lipoprotein; rare lipoprotein A 3292044..3293132 Escherichia coli ATCC 8739 6065980 YP_001725965.1 CDS EcolC_3013 NC_010468.1 3293199 3294482 D penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 3293199..3294482 Escherichia coli ATCC 8739 6065984 YP_001725966.1 CDS EcolC_3014 NC_010468.1 3294592 3294855 D PFAM: protein of unknown function DUF493; KEGG: sdy:SDY_0553 hypothetical protein; hypothetical protein 3294592..3294855 Escherichia coli ATCC 8739 6065985 YP_001725967.1 CDS lipB NC_010468.1 3294956 3295597 D lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 3294956..3295597 Escherichia coli ATCC 8739 6065988 YP_001725968.1 CDS EcolC_3016 NC_010468.1 3295857 3296810 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_0697 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 3295857..3296810 Escherichia coli ATCC 8739 6065991 YP_001725969.1 CDS EcolC_3017 NC_010468.1 3297019 3297984 D catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 3297019..3297984 Escherichia coli ATCC 8739 6065998 YP_001725970.1 CDS tatE NC_010468.1 3298085 3298288 R TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E complement(3298085..3298288) Escherichia coli ATCC 8739 6066000 YP_001725971.1 CDS EcolC_3020 NC_010468.1 3299297 3299680 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 3299297..3299680 Escherichia coli ATCC 8739 6066007 YP_001725972.1 CDS cspE NC_010468.1 3299734 3299943 R member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE complement(3299734..3299943) Escherichia coli ATCC 8739 6066015 YP_001725973.1 CDS pagP NC_010468.1 3300118 3300678 R catalyzes the transfer of palmitate to lipid A; palmitoyl transferase complement(3300118..3300678) Escherichia coli ATCC 8739 6066016 YP_001725974.1 CDS dcuC NC_010468.1 3301267 3302652 D responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 3301267..3302652 Escherichia coli ATCC 8739 6066017 YP_001725975.1 CDS dpiA NC_010468.1 3302693 3303373 R regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA complement(3302693..3303373) Escherichia coli ATCC 8739 6066630 YP_001725976.1 CDS EcolC_3025 NC_010468.1 3303342 3305000 R PFAM: ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; KEGG: ssn:SSON_0572 putative sensor-type protein; signal transduction histidine kinase regulating citrate/malate metabolism complement(3303342..3305000) Escherichia coli ATCC 8739 6066019 YP_001725977.1 CDS EcolC_3026 NC_010468.1 3305380 3306438 D KEGG: sbo:SBO_0483 citrate lyase synthetase; TIGRFAM: cytidyltransferase-related domain protein; citrate lyase ligase; PFAM: GCN5-related N-acetyltransferase; Citrate lyase ligase domain protein; citrate lyase ligase 3305380..3306438 Escherichia coli ATCC 8739 6066026 YP_001725978.1 CDS EcolC_3027 NC_010468.1 3306453 3306749 D acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 3306453..3306749 Escherichia coli ATCC 8739 6065948 YP_001725979.1 CDS EcolC_3028 NC_010468.1 3306746 3307654 D KEGG: sbo:SBO_0481 citrate lyase beta chain, acyl lyase subunit; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase; citrate lyase subunit beta 3306746..3307654 Escherichia coli ATCC 8739 6066029 YP_001725980.1 CDS EcolC_3029 NC_010468.1 3307665 3309197 D KEGG: ssn:SSON_0567 citrate lyase alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase alpha subunit; citrate lyase subunit alpha 3307665..3309197 Escherichia coli ATCC 8739 6065185 YP_001725981.1 CDS citX NC_010468.1 3309201 3309752 D 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 3309201..3309752 Escherichia coli ATCC 8739 6065423 YP_001725982.1 CDS citG NC_010468.1 3309727 3310605 D catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 3309727..3310605 Escherichia coli ATCC 8739 6066044 YP_001725983.1 CDS EcolC_3032 NC_010468.1 3310656 3312119 D TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: sbo:SBO_0477 putative a membrane protein; anion transporter 3310656..3312119 Escherichia coli ATCC 8739 6066047 YP_001725984.1 CDS EcolC_3033 NC_010468.1 3312215 3313039 D PFAM: ribonuclease T2; KEGG: sfx:S0535 RNase I; ribonuclease I 3312215..3313039 Escherichia coli ATCC 8739 6066052 YP_001725985.1 CDS EcolC_3034 NC_010468.1 3313269 3313679 D Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 3313269..3313679 Escherichia coli ATCC 8739 6066056 YP_001725986.1 CDS EcolC_3035 NC_010468.1 3313910 3315148 R PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sbo:SBO_0473 putative oxidoreductase; alcohol dehydrogenase complement(3313910..3315148) Escherichia coli ATCC 8739 6066058 YP_001725987.1 CDS EcolC_3036 NC_010468.1 3315369 3315797 D PFAM: UspA domain protein; KEGG: sdy:SDY_0542 hypothetical protein; UspA domain-containing protein 3315369..3315797 Escherichia coli ATCC 8739 6065977 YP_001725988.1 CDS EcolC_3037 NC_010468.1 3315918 3317513 R TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbo:SBO_0471 alkyl hydroperoxide reductase, F52a subunit; alkyl hydroperoxide reductase subunit F complement(3315918..3317513) Escherichia coli ATCC 8739 6066060 YP_001725989.1 CDS EcolC_3038 NC_010468.1 3317728 3318291 R with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C complement(3317728..3318291) Escherichia coli ATCC 8739 6066068 YP_001725990.1 CDS dsbG NC_010468.1 3318663 3319409 D Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 3318663..3319409 Escherichia coli ATCC 8739 6066069 YP_001725991.1 CDS EcolC_3040 NC_010468.1 3319618 3320520 D PFAM: regulatory protein LysR; KEGG: sfv:SFV_0557 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 3319618..3320520 Escherichia coli ATCC 8739 6066073 YP_001725992.1 CDS EcolC_3041 NC_010468.1 3320667 3321887 D PFAM: phosphoadenosine phosphosulfate reductase; KEGG: cko:CKO_02557 hypothetical protein; phosphoadenosine phosphosulfate reductase 3320667..3321887 Escherichia coli ATCC 8739 6066080 YP_001725993.1 CDS EcolC_3042 NC_010468.1 3321872 3322489 D PFAM: ParB domain protein nuclease; KEGG: ssn:SSON_0553 hypothetical protein; nuclease 3321872..3322489 Escherichia coli ATCC 8739 6066083 YP_001725994.1 CDS EcolC_3043 NC_010468.1 3322490 3323650 R catalyzes the transfer of an amino moiety; putative aminotransferase complement(3322490..3323650) Escherichia coli ATCC 8739 6065622 YP_001725995.1 CDS EcolC_3044 NC_010468.1 3323759 3324847 D member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 3323759..3324847 Escherichia coli ATCC 8739 6065944 YP_001725996.1 CDS EcolC_3045 NC_010468.1 3324857 3325054 R PFAM: protein of unknown function DUF466; KEGG: sdy:SDY_0530 hypothetical protein; hypothetical protein complement(3324857..3325054) Escherichia coli ATCC 8739 6066089 YP_001725997.1 CDS EcolC_3046 NC_010468.1 3325237 3327342 R PFAM: carbon starvation protein CstA; KEGG: sbo:SBO_0459 carbon starvation protein; carbon starvation protein CstA complement(3325237..3327342) Escherichia coli ATCC 8739 6066092 YP_001725998.1 CDS EcolC_3047 NC_010468.1 3327523 3327936 R PFAM: thioesterase superfamily protein; KEGG: sdy:SDY_0528 hypothetical protein; hypothetical protein complement(3327523..3327936) Escherichia coli ATCC 8739 6066097 YP_001725999.1 CDS EcolC_3048 NC_010468.1 3327939 3328685 R catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase complement(3327939..3328685) Escherichia coli ATCC 8739 6066110 YP_001726000.1 CDS EcolC_3049 NC_010468.1 3328685 3329542 R PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: sfl:SF0509 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase; isochorismatase complement(3328685..3329542) Escherichia coli ATCC 8739 6066116 YP_001726001.1 CDS entE NC_010468.1 3329556 3331166 R bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E complement(3329556..3331166) Escherichia coli ATCC 8739 6066118 YP_001726002.1 CDS EcolC_3051 NC_010468.1 3331176 3332351 R TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: sdy:SDY_0524 isochorismate hydroxymutase 2; isochorismate synthase complement(3331176..3332351) Escherichia coli ATCC 8739 6066120 YP_001726003.1 CDS EcolC_3052 NC_010468.1 3332726 3333682 D with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 3332726..3333682 Escherichia coli ATCC 8739 6066124 YP_001726004.1 CDS EcolC_3053 NC_010468.1 3333686 3334936 R protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS complement(3333686..3334936) Escherichia coli ATCC 8739 6066134 YP_001726005.1 CDS EcolC_3054 NC_010468.1 3335047 3336051 D with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 3335047..3336051 Escherichia coli ATCC 8739 6065761 YP_001726006.1 CDS EcolC_3055 NC_010468.1 3336048 3337040 D with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 3336048..3337040 Escherichia coli ATCC 8739 6066140 YP_001726007.1 CDS EcolC_3056 NC_010468.1 3337037 3337852 D with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 3337037..3337852 Escherichia coli ATCC 8739 6066142 YP_001726008.1 CDS EcolC_3057 NC_010468.1 3337849 3338982 R part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE complement(3337849..3338982) Escherichia coli ATCC 8739 6064678 YP_001726009.1 CDS entF NC_010468.1 3339198 3343079 R with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F complement(3339198..3343079) Escherichia coli ATCC 8739 6066145 YP_001726010.1 CDS EcolC_3059 NC_010468.1 3343076 3343294 R PFAM: MbtH domain protein; KEGG: sbo:SBO_0446 putative cytoplasmic protein; MbtH domain-containing protein complement(3343076..3343294) Escherichia coli ATCC 8739 6066150 YP_001726011.1 CDS EcolC_3060 NC_010468.1 3343297 3344499 R PFAM: putative esterase; KEGG: sfv:SFV_0530 enterochelin esterase; enterobactin/ferric enterobactin esterase complement(3343297..3344499) Escherichia coli ATCC 8739 6066152 YP_001726012.1 CDS EcolC_3061 NC_010468.1 3344742 3346982 D Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 3344742..3346982 Escherichia coli ATCC 8739 6066153 YP_001726013.1 CDS EcolC_3062 NC_010468.1 3347148 3347777 D PFAM: 4'-phosphopantetheinyl transferase; KEGG: ssn:SSON_0533 enterochelin synthetase, component D; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 3347148..3347777 Escherichia coli ATCC 8739 6066155 YP_001726014.1 CDS EcolC_3063 NC_010468.1 3348059 3349171 R PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein complement(3348059..3349171) Escherichia coli ATCC 8739 6065336 YP_001726015.1 CDS EcolC_3064 NC_010468.1 3349248 3349400 R PFAM: Hok/gef cell toxic protein; KEGG: sfx:S0500 hypothetical protein; Hok/gef cell toxic protein complement(3349248..3349400) Escherichia coli ATCC 8739 6066158 YP_001726016.1 CDS EcolC_3065 NC_010468.1 3349853 3350971 D ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 3349853..3350971 Escherichia coli ATCC 8739 6066162 YP_001726017.1 CDS EcolC_3066 NC_010468.1 3351037 3351285 D PFAM: protein of unknown function DUF1158; KEGG: sbo:SBO_0441 hypothetical protein; hypothetical protein 3351037..3351285 Escherichia coli ATCC 8739 6066163 YP_001726018.1 CDS EcolC_3067 NC_010468.1 3351350 3351718 D PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_0492 hypothetical protein; hypothetical protein 3351350..3351718 Escherichia coli ATCC 8739 6066164 YP_001726019.1 CDS EcolC_3068 NC_010468.1 3351812 3352465 D catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 3351812..3352465 Escherichia coli ATCC 8739 6066167 YP_001726020.1 CDS EcolC_3069 NC_010468.1 3352573 3353820 D PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0528 putative transport; mechanosensitive ion channel MscS 3352573..3353820 Escherichia coli ATCC 8739 6065453 YP_001726021.1 CDS EcolC_3070 NC_010468.1 3353888 3355300 R PFAM: amino acid permease-associated region; KEGG: sfv:SFV_0516 phenylalanine-specific transport system; phenylalanine transporter complement(3353888..3355300) Escherichia coli ATCC 8739 6066169 YP_001726022.1 CDS EcolC_3071 NC_010468.1 3355366 3358509 R TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: ssn:SSON_0526 putative inner membrane component for iron transport; CzcA family heavy metal efflux protein complement(3355366..3358509) Escherichia coli ATCC 8739 6066171 YP_001726023.1 CDS EcolC_3072 NC_010468.1 3358521 3359744 R with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB complement(3358521..3359744) Escherichia coli ATCC 8739 6066175 YP_001726024.1 CDS EcolC_3073 NC_010468.1 3359760 3360092 R KEGG: sfv:SFV_0506 hypothetical protein; copper-binding protein complement(3359760..3360092) Escherichia coli ATCC 8739 6066176 YP_001726025.1 CDS EcolC_3074 NC_010468.1 3360250 3361623 R with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC complement(3360250..3361623) Escherichia coli ATCC 8739 6064676 YP_001726026.1 CDS EcolC_3075 NC_010468.1 3361780 3362463 D response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 3361780..3362463 Escherichia coli ATCC 8739 6066179 YP_001726027.1 CDS EcolC_3076 NC_010468.1 3362453 3363901 D KEGG: ssn:SSON_0521 putative 2-component sensor protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; sensor kinase CusS 3362453..3363901 Escherichia coli ATCC 8739 6066181 YP_001726028.1 CDS EcolC_3077 NC_010468.1 3364638 3366539 D TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ssn:SSON_0520 putative Vgr protein; ImpA family type VI secretion-associated protein 3364638..3366539 Escherichia coli ATCC 8739 6066183 YP_001726029.1 CDS EcolC_3078 NC_010468.1 3366567 3367028 D PFAM: Domain of unknown function DUF1795; KEGG: ssn:SSON_0519 hypothetical protein; hypothetical protein 3366567..3367028 Escherichia coli ATCC 8739 6066187 YP_001726030.1 CDS EcolC_3079 NC_010468.1 3367048 3371565 D TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; PAAR repeat-containing protein; KEGG: ssn:SSON_0517 rhs core protein with extension; YD repeat-containing protein 3367048..3371565 Escherichia coli ATCC 8739 6066190 YP_001726031.1 CDS EcolC_3080 NC_010468.1 3371598 3371858 D hypothetical protein 3371598..3371858 Escherichia coli ATCC 8739 6066197 YP_001726032.1 CDS EcolC_3081 NC_010468.1 3371858 3372145 D hypothetical protein 3371858..3372145 Escherichia coli ATCC 8739 6066198 YP_001726033.1 CDS EcolC_3082 NC_010468.1 3373110 3374246 D PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 putative receptor; transposase IS4 family protein 3373110..3374246 Escherichia coli ATCC 8739 6066203 YP_001726034.1 CDS nfrB NC_010468.1 3374517 3376754 D PFAM: General secretory system II protein E domain protein; KEGG: sfl:SF0470 bacteriophage N4 receptor, outer membrane protein; bacteriophage N4 adsorption protein B 3374517..3376754 Escherichia coli ATCC 8739 6066206 YP_001726035.1 CDS EcolC_3084 NC_010468.1 3376741 3379713 D PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ssn:SSON_0514 bacteriophage N4 receptor, outer membrane protein; bacteriophage N4 receptor, outer membrane subunit 3376741..3379713 Escherichia coli ATCC 8739 6066207 YP_001726036.1 CDS EcolC_3085 NC_010468.1 3379714 3380604 D KEGG: ssn:SSON_0513 hypothetical protein; hypothetical protein 3379714..3380604 Escherichia coli ATCC 8739 6065757 YP_001726037.1 CDS EcolC_3086 NC_010468.1 3380787 3381548 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_0512 envelope protein; AraC family transcriptional regulator 3380787..3381548 Escherichia coli ATCC 8739 6066218 YP_001726038.1 CDS EcolC_3087 NC_010468.1 3381913 3382545 D activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 3381913..3382545 Escherichia coli ATCC 8739 6066228 YP_001726039.1 CDS EcolC_3088 NC_010468.1 3382548 3383063 R PFAM: Fimbrial protein; KEGG: ssn:SSON_0507 putative fimbrial-like protein; putative fimbrial protein complement(3382548..3383063) Escherichia coli ATCC 8739 6066229 YP_001726040.1 CDS EcolC_3089 NC_010468.1 3383074 3384081 R KEGG: ssn:SSON_0506 involved in fimbrial asembly; fimbrial asembly protein complement(3383074..3384081) Escherichia coli ATCC 8739 6066234 YP_001726041.1 CDS EcolC_3090 NC_010468.1 3384094 3386703 R PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: cko:CKO_02625 hypothetical protein; fimbrial biogenesis outer membrane usher protein complement(3384094..3386703) Escherichia coli ATCC 8739 6066236 YP_001726042.1 CDS EcolC_3091 NC_010468.1 3386734 3387426 R PFAM: pili assembly chaperone; KEGG: sfx:S0470 putative chaperone; pili assembly chaperone complement(3386734..3387426) Escherichia coli ATCC 8739 6066238 YP_001726043.1 CDS EcolC_3092 NC_010468.1 3387646 3388188 R PFAM: Fimbrial protein; KEGG: sfx:S0469 putative fimbrial-like protein; fimbrial protein complement(3387646..3388188) Escherichia coli ATCC 8739 6066239 YP_001726044.1 CDS EcolC_3093 NC_010468.1 3388659 3389525 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3388659..3389525 Escherichia coli ATCC 8739 6066241 YP_001726045.1 CDS EcolC_3094 NC_010468.1 3389527 3389739 D KEGG: sdy:SDY_0280 hypothetical protein; hypothetical protein 3389527..3389739 Escherichia coli ATCC 8739 6066244 YP_001726046.1 CDS EcolC_3095 NC_010468.1 3389847 3390368 D PFAM: membrane-bound metal-dependent hydrolase; KEGG: sbo:SBO_0416 hypothetical protein; membrane-bound metal-dependent hydrolase 3389847..3390368 Escherichia coli ATCC 8739 6066246 YP_001726047.1 CDS cysS NC_010468.1 3390404 3391789 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(3390404..3391789) Escherichia coli ATCC 8739 6066247 YP_001726048.1 CDS EcolC_3097 NC_010468.1 3391963 3392457 D PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sfv:SFV_0483 peptidyl-prolyl cis-trans isomerase B (rotamase B); peptidyl-prolyl cis-trans isomerase B 3391963..3392457 Escherichia coli ATCC 8739 6066250 YP_001726049.1 CDS EcolC_3098 NC_010468.1 3392460 3393182 D catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 3392460..3393182 Escherichia coli ATCC 8739 6066253 YP_001726050.1 CDS EcolC_3099 NC_010468.1 3393300 3393809 D KEGG: sbo:SBO_0420 phosphoribosylaminoimidazole carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; phosphoribosylaminoimidazole carboxylase catalytic subunit 3393300..3393809 Escherichia coli ATCC 8739 6066256 YP_001726051.1 CDS EcolC_3100 NC_010468.1 3393806 3394873 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase 3393806..3394873 Escherichia coli ATCC 8739 6066260 YP_001726052.1 CDS EcolC_3101 NC_010468.1 3395012 3395905 R KEGG: ssn:SSON_0497 putative carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; carbamate kinase complement(3395012..3395905) Escherichia coli ATCC 8739 6064861 YP_001726053.1 CDS EcolC_3102 NC_010468.1 3395902 3396717 R KEGG: sbo:SBO_0423 putative carboxylase; putative carboxylase complement(3395902..3396717) Escherichia coli ATCC 8739 6066271 YP_001726054.1 CDS EcolC_3103 NC_010468.1 3396728 3397987 R PFAM: protein of unknown function DUF1116; KEGG: stm:STM0530 putative cytoplasmic protein; hypothetical protein complement(3396728..3397987) Escherichia coli ATCC 8739 6065218 YP_001726055.1 CDS EcolC_3104 NC_010468.1 3397997 3399664 R multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA complement(3397997..3399664) Escherichia coli ATCC 8739 6066282 YP_001726056.1 CDS EcolC_3105 NC_010468.1 3399981 3401030 D TIGRFAM: ureidoglycolate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; KEGG: stm:STM0528 ureidoglycolate dehydrogenase; ureidoglycolate dehydrogenase 3399981..3401030 Escherichia coli ATCC 8739 6066283 YP_001726057.1 CDS EcolC_3107 NC_010468.1 3402105 3403085 R PFAM: transposase IS4 family protein; KEGG: sao:SAOUHSC_00778 hypothetical protein; transposase IS4 family protein complement(3402105..3403085) Escherichia coli ATCC 8739 6066292 YP_001726058.1 CDS EcolC_3108 NC_010468.1 3403497 3404282 D TIGRFAM: allantoin catabolism protein; PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein; KEGG: sec:SC0565 putative glyoxylate utilization; hypothetical protein 3403497..3404282 Escherichia coli ATCC 8739 6064859 YP_001726059.1 CDS EcolC_3109 NC_010468.1 3404510 3405655 R PFAM: glycerate kinase; KEGG: stm:STM0525 glycerate kinase II; glycerate kinase complement(3404510..3405655) Escherichia coli ATCC 8739 6066298 YP_001726060.1 CDS EcolC_3110 NC_010468.1 3405677 3406978 R PFAM: Xanthine/uracil/vitamin C permease; KEGG: spt:SPA2199 putative permease protein; putative purine permease YbbY complement(3405677..3406978) Escherichia coli ATCC 8739 6066312 YP_001726061.1 CDS EcolC_3111 NC_010468.1 3407035 3408396 R Plays a crucial role on both purine and pyrimidine metabolism; allantoinase complement(3407035..3408396) Escherichia coli ATCC 8739 6066317 YP_001726062.1 CDS EcolC_3112 NC_010468.1 3408456 3409910 R TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sec:SC0561 putative allantoin permease; allantoin permease complement(3408456..3409910) Escherichia coli ATCC 8739 6066326 YP_001726063.1 CDS EcolC_3113 NC_010468.1 3410079 3410957 R KEGG: stm:STM0519 tartronic semialdehyde reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 2-hydroxy-3-oxopropionate reductase complement(3410079..3410957) Escherichia coli ATCC 8739 6066328 YP_001726064.1 CDS EcolC_3114 NC_010468.1 3411057 3411833 R KEGG: ssn:SSON_0503 glyoxylate-induced protein; TIGRFAM: hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; hydroxypyruvate isomerase complement(3411057..3411833) Escherichia coli ATCC 8739 6066330 YP_001726065.1 CDS EcolC_3115 NC_010468.1 3411846 3413627 R catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase complement(3411846..3413627) Escherichia coli ATCC 8739 6066333 YP_001726066.1 CDS EcolC_3116 NC_010468.1 3413717 3414532 R regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR complement(3413717..3414532) Escherichia coli ATCC 8739 6066337 YP_001726067.1 CDS EcolC_3117 NC_010468.1 3414610 3415092 R catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase complement(3414610..3415092) Escherichia coli ATCC 8739 6066340 YP_001726068.1 CDS EcolC_3118 NC_010468.1 3415322 3416248 D activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 3415322..3416248 Escherichia coli ATCC 8739 6066343 YP_001726069.1 CDS EcolC_3119 NC_010468.1 3416317 3417411 D catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 3416317..3417411 Escherichia coli ATCC 8739 6065052 YP_001726070.1 CDS EcolC_3120 NC_010468.1 3418124 3420538 R PFAM: protein of unknown function DUF214; KEGG: ssn:SSON_0485 putative oxidoreductase; hypothetical protein complement(3418124..3420538) Escherichia coli ATCC 8739 6065057 YP_001726071.1 CDS EcolC_3121 NC_010468.1 3420535 3421221 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0396 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein YbbA complement(3420535..3421221) Escherichia coli ATCC 8739 6064631 YP_001726072.1 CDS EcolC_3122 NC_010468.1 3421222 3421815 D PFAM: lipolytic protein G-D-S-L family; KEGG: ssn:SSON_0484 acyl-CoA thioesterase I; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 3421222..3421815 Escherichia coli ATCC 8739 6066354 YP_001726073.1 CDS EcolC_3123 NC_010468.1 3421844 3422614 D PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbo:SBO_0395 putative oxidoreductase; short chain dehydrogenase 3421844..3422614 Escherichia coli ATCC 8739 6066357 YP_001726074.1 CDS EcolC_3124 NC_010468.1 3422675 3423529 D PFAM: Thioredoxin domain; KEGG: sdy:SDY_0407 putative thioredoxin-like protein; thioredoxin domain-containing protein 3422675..3423529 Escherichia coli ATCC 8739 6066363 YP_001726075.1 CDS EcolC_3125 NC_010468.1 3423592 3424371 R PFAM: conserved hypothetical protein; KEGG: ssn:SSON_0480 putative metal resistance protein; hypothetical protein complement(3423592..3424371) Escherichia coli ATCC 8739 6066372 YP_001726076.1 CDS EcolC_3126 NC_010468.1 3424358 3425035 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0392 putative ATP-binding component of a transport system; putative ABC transporter ATP-binding protein YbbL complement(3424358..3425035) Escherichia coli ATCC 8739 6066373 YP_001726077.1 CDS EcolC_3127 NC_010468.1 3425181 3426098 D PFAM: band 7 protein; KEGG: sbo:SBO_0391 putative protease; hypothetical protein 3425181..3426098 Escherichia coli ATCC 8739 6066384 YP_001726078.1 CDS EcolC_3128 NC_010468.1 3426095 3426553 D PFAM: protein of unknown function DUF107; KEGG: sbo:SBO_0390 hypothetical protein; hypothetical protein 3426095..3426553 Escherichia coli ATCC 8739 6066388 YP_001726079.1 CDS EcolC_3129 NC_010468.1 3426554 3426961 R activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR complement(3426554..3426961) Escherichia coli ATCC 8739 6066390 YP_001726080.1 CDS EcolC_3130 NC_010468.1 3427086 3428378 R PFAM: Spore germination protein; amino acid permease-associated region; KEGG: ssn:SSON_0475 putative amino acid/amine transport protein; amino acid permease-associated protein complement(3427086..3428378) Escherichia coli ATCC 8739 6066391 YP_001726081.1 CDS EcolC_3131 NC_010468.1 3428381 3429313 R catalyzes the formation of glutamate from glutamine; glutaminase complement(3428381..3429313) Escherichia coli ATCC 8739 6065800 YP_001726082.1 CDS copA NC_010468.1 3429575 3432079 D TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sbo:SBO_0386 putative ATPase; copper exporting ATPase 3429575..3432079 Escherichia coli ATCC 8739 6066393 YP_001726083.1 CDS EcolC_3133 NC_010468.1 3433001 3433396 R TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: sbo:SBO_0385 hypothetical protein; XRE family plasmid maintenance system antidote protein complement(3433001..3433396) Escherichia coli ATCC 8739 6065302 YP_001726084.1 CDS EcolC_3134 NC_010468.1 3433480 3434274 D PFAM: GumN family protein; KEGG: sfv:SFV_0455 putative ligase; GumN family protein 3433480..3434274 Escherichia coli ATCC 8739 6066401 YP_001726085.1 CDS EcolC_3135 NC_010468.1 3434478 3434957 D TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sfv:SFV_0454 hypothetical protein; hypothetical protein 3434478..3434957 Escherichia coli ATCC 8739 6066406 YP_001726086.1 CDS ushA NC_010468.1 3434994 3436646 R catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic complement(3434994..3436646) Escherichia coli ATCC 8739 6066411 YP_001726087.1 CDS EcolC_3137 NC_010468.1 3436864 3438084 D PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0431 fosmidomycin resistance protein; major facilitator transporter 3436864..3438084 Escherichia coli ATCC 8739 6066412 YP_001726088.1 CDS EcolC_3138 NC_010468.1 3438322 3439998 D YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein 3438322..3439998 Escherichia coli ATCC 8739 6066417 YP_001726089.1 CDS EcolC_3139 NC_010468.1 3440131 3441435 R PFAM: PfkB domain protein; KEGG: sbo:SBO_0377 inosine-guanosine kinase; inosine kinase complement(3440131..3441435) Escherichia coli ATCC 8739 6066418 YP_001726090.1 CDS EcolC_3140 NC_010468.1 3441587 3442546 D PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ssn:SSON_0463 putative lipase; acetyl esterase 3441587..3442546 Escherichia coli ATCC 8739 6065328 YP_001726091.1 CDS hemH NC_010468.1 3442543 3443505 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(3442543..3443505) Escherichia coli ATCC 8739 6066432 YP_001726092.1 CDS adk NC_010468.1 3443741 3444385 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(3443741..3444385) Escherichia coli ATCC 8739 6066449 YP_001726093.1 CDS EcolC_3143 NC_010468.1 3444566 3446440 R molecular chaperone; heat shock protein 90 complement(3444566..3446440) Escherichia coli ATCC 8739 6065841 YP_001726094.1 CDS recR NC_010468.1 3446550 3447155 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(3446550..3447155) Escherichia coli ATCC 8739 6066466 YP_001726095.1 CDS EcolC_3145 NC_010468.1 3447155 3447484 R PFAM: conserved hypothetical protein; KEGG: sdy:SDY_0448 hypothetical protein; hypothetical protein complement(3447155..3447484) Escherichia coli ATCC 8739 6066467 YP_001726096.1 CDS EcolC_3146 NC_010468.1 3447537 3449468 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(3447537..3449468) Escherichia coli ATCC 8739 6066293 YP_001726097.1 CDS EcolC_3147 NC_010468.1 3449597 3450148 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(3449597..3450148) Escherichia coli ATCC 8739 6066468 YP_001726098.1 CDS EcolC_3148 NC_010468.1 3450301 3450678 R PFAM: protein of unknown function DUF454; KEGG: sdy:SDY_0451 putative gene 58; hypothetical protein complement(3450301..3450678) Escherichia coli ATCC 8739 6066472 YP_001726099.1 CDS EcolC_3149 NC_010468.1 3450748 3451275 D PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 3450748..3451275 Escherichia coli ATCC 8739 6066475 YP_001726100.1 CDS EcolC_3150 NC_010468.1 3451289 3451450 D KEGG: sbo:SBO_0366 hypothetical protein; hypothetical protein 3451289..3451450 Escherichia coli ATCC 8739 6066480 YP_001726101.1 CDS EcolC_3151 NC_010468.1 3451662 3455024 R small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA complement(3451662..3455024) Escherichia coli ATCC 8739 6066481 YP_001726102.1 CDS EcolC_3152 NC_010468.1 3455152 3455799 R regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR complement(3455152..3455799) Escherichia coli ATCC 8739 6066483 YP_001726103.1 CDS EcolC_3153 NC_010468.1 3455941 3457134 D TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_0450 acridine efflux pump; RND family efflux transporter MFP subunit 3455941..3457134 Escherichia coli ATCC 8739 6066485 YP_001726104.1 CDS EcolC_3154 NC_010468.1 3457157 3460306 D TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_0362 acridine efflux pump; hydrophobe/amphiphile efflux-1 (HAE1) family protein 3457157..3460306 Escherichia coli ATCC 8739 6066489 YP_001726105.1 CDS EcolC_3155 NC_010468.1 3460852 3461226 D KEGG: sdy:SDY_0458 hypothetical protein; hypothetical protein 3460852..3461226 Escherichia coli ATCC 8739 6066498 YP_001726106.1 CDS EcolC_3156 NC_010468.1 3461240 3461470 D with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 3461240..3461470 Escherichia coli ATCC 8739 6066501 YP_001726107.1 CDS EcolC_3157 NC_010468.1 3461642 3462193 D PFAM: transferase hexapeptide repeat containing protein; KEGG: sdy:SDY_0460 putative transferase; maltose O-acetyltransferase 3461642..3462193 Escherichia coli ATCC 8739 6066506 YP_001726108.1 CDS EcolC_3158 NC_010468.1 3462309 3462779 D KEGG: sdy:SDY_0461 hypothetical protein; hypothetical protein 3462309..3462779 Escherichia coli ATCC 8739 6064449 YP_001726109.1 CDS EcolC_3159 NC_010468.1 3462943 3464493 D PFAM: EAL domain protein; KEGG: sfv:SFV_0431 hypothetical protein; EAL domain-containing protein 3462943..3464493 Escherichia coli ATCC 8739 6066513 YP_001726110.1 CDS EcolC_3160 NC_010468.1 3464535 3464888 R PFAM: protein of unknown function DUF1428; KEGG: sdy:SDY_0392 hypothetical protein; hypothetical protein complement(3464535..3464888) Escherichia coli ATCC 8739 6066515 YP_001726111.1 CDS EcolC_3161 NC_010468.1 3465267 3465578 D TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: sdy:SDY_0391 hypothetical protein; methylated-DNA--protein-cysteine methyltransferase 3465267..3465578 Escherichia coli ATCC 8739 6066520 YP_001726112.1 CDS EcolC_3162 NC_010468.1 3465609 3466181 R KEGG: sfv:SFV_0427 glycoprotein/polysaccharide metabolism; glycoprotein/polysaccharide metabolism complement(3465609..3466181) Escherichia coli ATCC 8739 6066527 YP_001726113.1 CDS EcolC_3163 NC_010468.1 3466399 3467259 D KEGG: ssn:SSON_0440 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; acyl-CoA thioesterase II 3466399..3467259 Escherichia coli ATCC 8739 6066528 YP_001726114.1 CDS EcolC_3164 NC_010468.1 3467308 3468594 R TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ssn:SSON_0439 probable ammonium transporter; ammonium transporter complement(3467308..3468594) Escherichia coli ATCC 8739 6066534 YP_001726115.1 CDS EcolC_3165 NC_010468.1 3468624 3468962 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 complement(3468624..3468962) Escherichia coli ATCC 8739 6066537 YP_001726116.1 CDS EcolC_3166 NC_010468.1 3469143 3470924 R PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sbo:SBO_0344 putative ATP-binding component of a transport system; putative multidrug transporter membrane\ATP-binding proteins complement(3469143..3470924) Escherichia coli ATCC 8739 6066540 YP_001726117.1 CDS EcolC_3167 NC_010468.1 3470917 3472689 R PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sdy:SDY_0385 ATP-binding component of a transport system; putative multidrug transporter membrane\ATP-binding proteins complement(3470917..3472689) Escherichia coli ATCC 8739 6066542 YP_001726118.1 CDS EcolC_3168 NC_010468.1 3472719 3473177 R PFAM: regulatory protein AsnC/Lrp family; KEGG: sbo:SBO_0341 putative LRP-like transcriptional regulator; AsnC family transcriptional regulator complement(3472719..3473177) Escherichia coli ATCC 8739 6065344 YP_001726119.1 CDS EcolC_3169 NC_010468.1 3473330 3474097 R TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: ssn:SSON_0434 hypothetical protein; cof family hydrolase complement(3473330..3474097) Escherichia coli ATCC 8739 6066554 YP_001726120.1 CDS EcolC_3170 NC_010468.1 3474099 3474796 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(3474099..3474542,3474542..3474796)) Escherichia coli ATCC 8739 6066556 YP_001726121.1 CDS EcolC_3171 NC_010468.1 3474876 3475573 R PFAM: Insertion element protein; KEGG: sfx:S4666 IS1 orfA; insertion element protein complement(join(3474876..3475319,3475319..3475573)) Escherichia coli ATCC 8739 6065639 YP_001726122.1 CDS EcolC_3172 NC_010468.1 3475881 3477305 D TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase; KEGG: eca:ECA0499 putative capsular polysaccharide biosynthesis protein; undecaprenyl-phosphate glucose phosphotransferase 3475881..3477305 Escherichia coli ATCC 8739 6066564 YP_001726123.1 CDS EcolC_3173 NC_010468.1 3477295 3478581 D KEGG: eca:ECA0500 putative capsular polysaccharide biosynthesis protein; putative capsular polysaccharide biosynthesis protein 3477295..3478581 Escherichia coli ATCC 8739 6066568 YP_001726124.1 CDS EcolC_3174 NC_010468.1 3478583 3479140 D PFAM: polysaccharide export protein; KEGG: eca:ECA0501 putative capsular polysaccharide export protein; polysaccharide export protein 3478583..3479140 Escherichia coli ATCC 8739 6066571 YP_001726125.1 CDS EcolC_3175 NC_010468.1 3479143 3481275 D PFAM: lipopolysaccharide biosynthesis protein; KEGG: eca:ECA0502 putative capsulatr polysaccharide biosynthesis protein; lipopolysaccharide biosynthesis protein 3479143..3481275 Escherichia coli ATCC 8739 6066572 YP_001726126.1 CDS EcolC_3176 NC_010468.1 3481272 3482483 D KEGG: eca:ECA0503 putative capsular polysaccharide bisynthesis protein; capsular polysacharride biosynthesis protein 3481272..3482483 Escherichia coli ATCC 8739 6065747 YP_001726127.1 CDS EcolC_3177 NC_010468.1 3482480 3483865 D KEGG: eca:ECA0504 putative capsular polysaccharide bisynthesis protein; capsular polysacharride biosynthesis protein 3482480..3483865 Escherichia coli ATCC 8739 6066579 YP_001726128.1 CDS EcolC_3178 NC_010468.1 3483855 3484844 D PFAM: glycosyl transferase family 2; KEGG: eca:ECA0505 probable capsular polysaccharide bisynthesis glycosyl transferase; glycosyl transferase family protein 3483855..3484844 Escherichia coli ATCC 8739 6066084 YP_001726129.1 CDS EcolC_3179 NC_010468.1 3484858 3486069 D PFAM: glycosyl transferase group 1; KEGG: eca:ECA0506 probable capsular polysaccharide bisynthesis glycosyl transferase; group 1 glycosyl transferase 3484858..3486069 Escherichia coli ATCC 8739 6066580 YP_001726130.1 CDS EcolC_3180 NC_010468.1 3486071 3487183 D PFAM: glycosyl transferase group 1; Protein of unknown function DUF1972; KEGG: eca:ECA0507 putative capsular polysaccharide bisynthesis glycosyl transferase; group 1 glycosyl transferase 3486071..3487183 Escherichia coli ATCC 8739 6066582 YP_001726131.1 CDS EcolC_3181 NC_010468.1 3487186 3487593 D KEGG: eca:ECA0508 hypothetical protein; hypothetical protein 3487186..3487593 Escherichia coli ATCC 8739 6066583 YP_001726132.1 CDS EcolC_3182 NC_010468.1 3487616 3489019 D KEGG: eca:ECA0509 hypothetical protein; hypothetical protein 3487616..3489019 Escherichia coli ATCC 8739 6066585 YP_001726133.1 CDS EcolC_3183 NC_010468.1 3489067 3490086 R TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: plu:plu4831 UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase); UDP-glucose 4-epimerase complement(3489067..3490086) Escherichia coli ATCC 8739 6066588 YP_001726134.1 CDS EcolC_3184 NC_010468.1 3490163 3491089 R KEGG: pdi:BDI_0028 conserved hypothetical protein, putative glycosyltransferase; hypothetical protein complement(3490163..3491089) Escherichia coli ATCC 8739 6066589 YP_001726135.1 CDS EcolC_3185 NC_010468.1 3491436 3492133 D PFAM: Insertion element protein; KEGG: sfx:S4666 IS1 orfA; insertion element protein join(3491436..3491690,3491690..3492133) Escherichia coli ATCC 8739 6066590 YP_001726136.1 CDS EcolC_3187 NC_010468.1 3492321 3494021 D PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_0339 hypothetical protein; extracellular solute-binding protein 3492321..3494021 Escherichia coli ATCC 8739 6065561 YP_001726137.1 CDS EcolC_3188 NC_010468.1 3494086 3494781 D YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 3494086..3494781 Escherichia coli ATCC 8739 6066605 YP_001726138.1 CDS EcolC_3189 NC_010468.1 3494833 3495231 R PFAM: thioesterase superfamily protein; KEGG: sbo:SBO_0337 hypothetical protein; thioesterase superfamily protein complement(3494833..3495231) Escherichia coli ATCC 8739 6066607 YP_001726139.1 CDS EcolC_3190 NC_010468.1 3495337 3495708 R TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: sdy:SDY_0290 hypothetical protein; helix-hairpin-helix repeat-containing competence protein ComEA complement(3495337..3495708) Escherichia coli ATCC 8739 6066609 YP_001726140.1 CDS EcolC_3191 NC_010468.1 3495859 3497730 R PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: sbo:SBO_0335 putative protease maturation protein; peptidyl-prolyl cis-trans isomerase D complement(3495859..3497730) Escherichia coli ATCC 8739 6066612 YP_001726141.1 CDS EcolC_3192 NC_010468.1 3497922 3498194 R histone-like DNA-binding protein; transcriptional regulator HU subunit beta complement(3497922..3498194) Escherichia coli ATCC 8739 6066614 YP_001726142.1 CDS EcolC_3193 NC_010468.1 3498403 3500757 R KEGG: ssn:SSON_0422 DNA-binding, ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; DNA-binding ATP-dependent protease La complement(3498403..3500757) Escherichia coli ATCC 8739 6066618 YP_001726143.1 CDS clpX NC_010468.1 3500945 3502219 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(3500945..3502219) Escherichia coli ATCC 8739 6066621 YP_001726144.1 CDS clpP NC_010468.1 3502345 3502968 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(3502345..3502968) Escherichia coli ATCC 8739 6066622 YP_001726145.1 CDS tig NC_010468.1 3503214 3504512 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(3503214..3504512) Escherichia coli ATCC 8739 6066627 YP_001726146.1 CDS EcolC_3197 NC_010468.1 3504659 3504847 R KEGG: sdy:SDY_0297 hypothetical protein; hypothetical protein complement(3504659..3504847) Escherichia coli ATCC 8739 6065602 YP_001726147.1 CDS EcolC_3198 NC_010468.1 3504856 3505173 R positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA complement(3504856..3505173) Escherichia coli ATCC 8739 6066633 YP_001726148.1 CDS EcolC_3199 NC_010468.1 3505478 3506056 D PFAM: Uncharacterized lipoprotein; KEGG: ssn:SSON_0417 putative polymerase/proteinase; hypothetical protein 3505478..3506056 Escherichia coli ATCC 8739 6066645 YP_001726149.1 CDS ampG NC_010468.1 3506100 3507575 D in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 3506100..3507575 Escherichia coli ATCC 8739 6066349 YP_001726150.1 CDS EcolC_3201 NC_010468.1 3508037 3508984 D TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: sbo:SBO_0326 cytochrome o ubiquinol oxidase subunit II; cytochrome o ubiquinol oxidase subunit II 3508037..3508984 Escherichia coli ATCC 8739 6066653 YP_001726151.1 CDS EcolC_3202 NC_010468.1 3509006 3510997 D KEGG: ssn:SSON_0414 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase, subunit I; PFAM: cytochrome c oxidase subunit I; cytochrome o ubiquinol oxidase subunit I 3509006..3510997 Escherichia coli ATCC 8739 6066657 YP_001726152.1 CDS EcolC_3203 NC_010468.1 3510987 3511601 D TIGRFAM: cytochrome o ubiquinol oxidase, subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: ssn:SSON_0413 cytochrome o ubiquinol oxidase subunit III; cytochrome o ubiquinol oxidase subunit III 3510987..3511601 Escherichia coli ATCC 8739 6066663 YP_001726153.1 CDS EcolC_3204 NC_010468.1 3511601 3511930 D TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: sbo:SBO_0323 cytochrome o ubiquinol oxidase subunit IV; cytochrome o ubiquinol oxidase subunit IV 3511601..3511930 Escherichia coli ATCC 8739 6066664 YP_001726154.1 CDS EcolC_3205 NC_010468.1 3511942 3512832 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 3511942..3512832 Escherichia coli ATCC 8739 6066665 YP_001726155.1 CDS EcolC_3206 NC_010468.1 3512981 3514345 D PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_0303 putative transport protein; major facilitator transporter 3512981..3514345 Escherichia coli ATCC 8739 6066451 YP_001726156.1 CDS EcolC_3207 NC_010468.1 3514473 3514964 R putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein complement(3514473..3514964) Escherichia coli ATCC 8739 6066669 YP_001726157.1 CDS EcolC_3208 NC_010468.1 3515132 3516043 D ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 3515132..3516043 Escherichia coli ATCC 8739 6066674 YP_001726158.1 CDS EcolC_3209 NC_010468.1 3516006 3516596 D TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: ssn:SSON_0401 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis; DJ-1 family protein 3516006..3516596 Escherichia coli ATCC 8739 6066659 YP_001726159.1 CDS EcolC_3210 NC_010468.1 3516650 3518098 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(3516650..3518098) Escherichia coli ATCC 8739 6065677 YP_001726160.1 CDS EcolC_3211 NC_010468.1 3518304 3518546 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 3518304..3518546 Escherichia coli ATCC 8739 6066684 YP_001726161.1 CDS EcolC_3212 NC_010468.1 3518546 3519445 D PFAM: Polyprenyl synthetase; KEGG: sdy:SDY_0309 geranyltranstransferase; geranyltranstransferase 3518546..3519445 Escherichia coli ATCC 8739 6066469 YP_001726162.1 CDS EcolC_3213 NC_010468.1 3519470 3521332 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3519470..3521332 Escherichia coli ATCC 8739 6066691 YP_001726163.1 CDS EcolC_3214 NC_010468.1 3521512 3522486 D PFAM: aldo/keto reductase; KEGG: sdy:SDY_0311 putative NAD(P)H-dependent xylose reductase; aldo/keto reductase 3521512..3522486 Escherichia coli ATCC 8739 6066697 YP_001726164.1 CDS EcolC_3215 NC_010468.1 3522540 3523058 R hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A complement(3522540..3523058) Escherichia coli ATCC 8739 6066698 YP_001726165.1 CDS EcolC_3216 NC_010468.1 3523036 3524013 R catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase complement(3523036..3524013) Escherichia coli ATCC 8739 6066699 YP_001726166.1 CDS nusB NC_010468.1 3524091 3524510 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(3524091..3524510) Escherichia coli ATCC 8739 6066701 YP_001726167.1 CDS ribH NC_010468.1 3524530 3525000 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(3524530..3525000) Escherichia coli ATCC 8739 6066713 YP_001726168.1 CDS ribD NC_010468.1 3525089 3526192 R riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase complement(3525089..3526192) Escherichia coli ATCC 8739 6066717 YP_001726169.1 CDS nrdR NC_010468.1 3526196 3526645 R PFAM: ATP-cone domain protein; KEGG: sdy:SDY_0321 hypothetical protein; transcriptional regulator NrdR complement(3526196..3526645) Escherichia coli ATCC 8739 6066718 YP_001726170.1 CDS EcolC_3221 NC_010468.1 3526796 3527335 D KEGG: ssn:SSON_0389 hypothetical protein; hypothetical protein 3526796..3527335 Escherichia coli ATCC 8739 6066720 YP_001726171.1 CDS EcolC_3222 NC_010468.1 3527634 3528518 D PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: sdy:SDY_0323 nucleoside channel; nucleoside-specific channel-forming protein Tsx 3527634..3528518 Escherichia coli ATCC 8739 6066723 YP_001726172.1 CDS EcolC_3223 NC_010468.1 3528695 3529042 R PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: sdy:SDY_0324 hypothetical protein; hypothetical protein complement(3528695..3529042) Escherichia coli ATCC 8739 6066725 YP_001726173.1 CDS secF NC_010468.1 3529170 3530141 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(3529170..3530141) Escherichia coli ATCC 8739 6066726 YP_001726174.1 CDS secD NC_010468.1 3530152 3531966 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(3530152..3531966) Escherichia coli ATCC 8739 6066729 YP_001726175.1 CDS yajC NC_010468.1 3532027 3532359 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(3532027..3532359) Escherichia coli ATCC 8739 6064945 YP_001726176.1 CDS tgt NC_010468.1 3532382 3533509 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(3532382..3533509) Escherichia coli ATCC 8739 6066743 YP_001726177.1 CDS queA NC_010468.1 3533565 3534635 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(3533565..3534635) Escherichia coli ATCC 8739 6066744 YP_001726178.1 CDS EcolC_3229 NC_010468.1 3534728 3535309 D Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 3534728..3535309 Escherichia coli ATCC 8739 6066748 YP_001726179.1 CDS EcolC_3230 NC_010468.1 3535314 3537131 R PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ssn:SSON_0380 maltodextrin glucosidase; maltodextrin glucosidase complement(3535314..3537131) Escherichia coli ATCC 8739 6066764 YP_001726180.1 CDS proY NC_010468.1 3537287 3538660 R cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease complement(3537287..3538660) Escherichia coli ATCC 8739 6066766 YP_001726181.1 CDS EcolC_3232 NC_010468.1 3538736 3540055 R PFAM: branched-chain amino acid transport system II carrier protein; KEGG: sdy:SDY_0336 branched chain amino acid transport system II carrier protein; branched-chain amino acid transport system II carrier protein complement(3538736..3540055) Escherichia coli ATCC 8739 6066769 YP_001726182.1 CDS phoR NC_010468.1 3540462 3541757 R membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein complement(3540462..3541757) Escherichia coli ATCC 8739 6066771 YP_001726183.1 CDS EcolC_3234 NC_010468.1 3541815 3542504 R two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB complement(3541815..3542504) Escherichia coli ATCC 8739 6066779 YP_001726184.1 CDS EcolC_3235 NC_010468.1 3542694 3543896 D with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 3542694..3543896 Escherichia coli ATCC 8739 6066781 YP_001726185.1 CDS EcolC_3236 NC_010468.1 3543893 3547036 D with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 3543893..3547036 Escherichia coli ATCC 8739 6066787 YP_001726186.1 CDS EcolC_3237 NC_010468.1 3547162 3548346 D member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 3547162..3548346 Escherichia coli ATCC 8739 6066789 YP_001726187.1 CDS EcolC_3238 NC_010468.1 3548591 3549586 R catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase complement(3548591..3549586) Escherichia coli ATCC 8739 6066795 YP_001726188.1 CDS rdgC NC_010468.1 3549624 3550535 D Required for efficient pilin antigenic variation; recombination associated protein 3549624..3550535 Escherichia coli ATCC 8739 6064785 YP_001726189.1 CDS EcolC_3240 NC_010468.1 3550693 3550974 R KEGG: sfv:SFV_0357 hypothetical protein; hypothetical protein complement(3550693..3550974) Escherichia coli ATCC 8739 6066797 YP_001726190.1 CDS EcolC_3241 NC_010468.1 3551182 3551466 R PFAM: protein of unknown function DUF1255; KEGG: sbo:SBO_0286 hypothetical protein; hypothetical protein complement(3551182..3551466) Escherichia coli ATCC 8739 6066798 YP_001726191.1 CDS EcolC_3242 NC_010468.1 3551538 3552215 R PFAM: AroM family protein; KEGG: sbo:SBO_0285 AroM; hypothetical protein complement(3551538..3552215) Escherichia coli ATCC 8739 6066800 YP_001726192.1 CDS EcolC_3243 NC_010468.1 3552473 3552664 R KEGG: sbo:SBO_0284 hypothetical protein; hypothetical protein complement(3552473..3552664) Escherichia coli ATCC 8739 6066804 YP_001726193.1 CDS aroL NC_010468.1 3552714 3553238 R type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(3552714..3553238) Escherichia coli ATCC 8739 6066807 YP_001726194.1 CDS EcolC_3245 NC_010468.1 3553415 3553879 R PFAM: protein of unknown function DUF188; KEGG: sdy:SDY_0357 hypothetical protein; hypothetical protein complement(3553415..3553879) Escherichia coli ATCC 8739 6066810 YP_001726195.1 CDS EcolC_3246 NC_010468.1 3553999 3554808 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 3553999..3554808 Escherichia coli ATCC 8739 6066812 YP_001726196.1 CDS adrA NC_010468.1 3554825 3555940 R catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA complement(3554825..3555940) Escherichia coli ATCC 8739 6066813 YP_001726197.1 CDS EcolC_3248 NC_010468.1 3556042 3556362 R PFAM: PsiF repeat protein; KEGG: sbo:SBO_0279 PsiF; hypothetical protein complement(3556042..3556362) Escherichia coli ATCC 8739 6066819 YP_001726198.1 CDS EcolC_3249 NC_010468.1 3556481 3557896 R PFAM: Alkaline phosphatase; KEGG: sbo:SBO_0278 alkaline phosphatase; alkaline phosphatase complement(3556481..3557896) Escherichia coli ATCC 8739 6066034 YP_001726199.1 CDS EcolC_3250 NC_010468.1 3557997 3558257 R KEGG: ssn:SSON_0357 hypothetical protein; hypothetical protein complement(3557997..3558257) Escherichia coli ATCC 8739 6066821 YP_001726200.1 CDS ddl NC_010468.1 3558720 3559814 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 3558720..3559814 Escherichia coli ATCC 8739 6066822 YP_001726201.1 CDS EcolC_3252 NC_010468.1 3559838 3560050 R KEGG: sdy:SDY_0366 hypothetical protein; hypothetical protein complement(3559838..3560050) Escherichia coli ATCC 8739 6066826 YP_001726202.1 CDS EcolC_3253 NC_010468.1 3560310 3560618 D KEGG: sbo:SBO_0274 hypothetical protein; hypothetical protein 3560310..3560618 Escherichia coli ATCC 8739 6065894 YP_001726203.1 CDS EcolC_3254 NC_010468.1 3560677 3561771 R PFAM: protein of unknown function DUF1615; KEGG: sbo:SBO_0273 hypothetical protein; hypothetical protein complement(3560677..3561771) Escherichia coli ATCC 8739 6066828 YP_001726204.1 CDS EcolC_3255 NC_010468.1 3561784 3563004 R in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter complement(3561784..3563004) Escherichia coli ATCC 8739 6066041 YP_001726205.1 CDS EcolC_3256 NC_010468.1 3563356 3564513 D this protein has no known enzymatic function; beta-lactam binding protein AmpH 3563356..3564513 Escherichia coli ATCC 8739 6066831 YP_001726206.1 CDS EcolC_3257 NC_010468.1 3564514 3565137 R KEGG: ssn:SSON_0350 hypothetical protein; putative DNA-binding transcriptional regulator complement(3564514..3565137) Escherichia coli ATCC 8739 6066832 YP_001726207.1 CDS EcolC_3258 NC_010468.1 3565225 3568227 R TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: cko:CKO_02805 hypothetical protein; outer membrane autotransporter complement(3565225..3568227) Escherichia coli ATCC 8739 6066834 YP_001726208.1 CDS EcolC_3259 NC_010468.1 3568750 3569724 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 3568750..3569724 Escherichia coli ATCC 8739 6066839 YP_001726209.1 CDS tauD NC_010468.1 3569831 3570682 R catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase complement(3569831..3570682) Escherichia coli ATCC 8739 6066840 YP_001726210.1 CDS EcolC_3261 NC_010468.1 3570679 3571506 R PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfv:SFV_0331 taurine transport system permease protein; taurine transporter subunit complement(3570679..3571506) Escherichia coli ATCC 8739 6066841 YP_001726211.1 CDS tauB NC_010468.1 3571503 3572270 R Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit complement(3571503..3572270) Escherichia coli ATCC 8739 6066851 YP_001726212.1 CDS tauA NC_010468.1 3572283 3573245 R with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit complement(3572283..3573245) Escherichia coli ATCC 8739 6066854 YP_001726213.1 CDS EcolC_3264 NC_010468.1 3573861 3574532 D PFAM: LmbE family protein; KEGG: ssn:SSON_0340 hypothetical protein; LmbE family protein 3573861..3574532 Escherichia coli ATCC 8739 6065013 YP_001726214.1 CDS EcolC_3265 NC_010468.1 3574542 3575738 D PFAM: glycosyl transferase family 2; KEGG: aau:AAur_0762 glycosyl transferase, group 2 family domain protein; glycosyl transferase family protein 3574542..3575738 Escherichia coli ATCC 8739 6066857 YP_001726215.1 CDS EcolC_3266 NC_010468.1 3575857 3576297 D KEGG: ssn:SSON_0338 putative transferase; putative transferase 3575857..3576297 Escherichia coli ATCC 8739 6066274 YP_001726216.1 CDS EcolC_3267 NC_010468.1 3576299 3577072 D KEGG: ssn:SSON_0337 hypothetical protein; hypothetical protein 3576299..3577072 Escherichia coli ATCC 8739 6066863 YP_001726217.1 CDS EcolC_3268 NC_010468.1 3577258 3577533 D formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 3577258..3577533 Escherichia coli ATCC 8739 6064941 YP_001726218.1 CDS EcolC_3269 NC_010468.1 3577568 3578677 D TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_0335 alcohol dehydrogenase class III; S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3577568..3578677 Escherichia coli ATCC 8739 6066867 YP_001726219.1 CDS EcolC_3270 NC_010468.1 3578770 3579603 D KEGG: ssn:SSON_0334 putative esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; S-formylglutathione hydrolase 3578770..3579603 Escherichia coli ATCC 8739 6065536 YP_001726220.1 CDS EcolC_3271 NC_010468.1 3579829 3580368 R KEGG: ssn:SSON_0333 nucleoprotein/polynucleotide-associated enzyme; nucleoprotein/polynucleotide-associated protein complement(3579829..3580368) Escherichia coli ATCC 8739 6066871 YP_001726221.1 CDS EcolC_3272 NC_010468.1 3580470 3581681 R TIGRFAM: benzoate transport; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_0332 putative transport protein; putative 3-hydroxyphenylpropionic transporter MhpT complement(3580470..3581681) Escherichia coli ATCC 8739 6066896 YP_001726222.1 CDS EcolC_3273 NC_010468.1 3582158 3583171 R catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase complement(3582158..3583171) Escherichia coli ATCC 8739 6065774 YP_001726223.1 CDS EcolC_3274 NC_010468.1 3583168 3584118 R catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase complement(3583168..3584118) Escherichia coli ATCC 8739 6066910 YP_001726224.1 CDS mhpD NC_010468.1 3584115 3584924 R catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase complement(3584115..3584924) Escherichia coli ATCC 8739 6066915 YP_001726225.1 CDS EcolC_3276 NC_010468.1 3584934 3585800 R PFAM: alpha/beta hydrolase fold; KEGG: kpn:KPN_02120 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; alpha/beta hydrolase fold protein complement(3584934..3585800) Escherichia coli ATCC 8739 6065694 YP_001726226.1 CDS mhpB NC_010468.1 3585818 3586762 R catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase complement(3585818..3586762) Escherichia coli ATCC 8739 6066918 YP_001726227.1 CDS mhpA NC_010468.1 3586764 3588428 R catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase complement(3586764..3588428) Escherichia coli ATCC 8739 6066939 YP_001726228.1 CDS EcolC_3279 NC_010468.1 3588607 3589452 D activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 3588607..3589452 Escherichia coli ATCC 8739 6066679 YP_001726229.1 CDS lacI NC_010468.1 3589520 3590611 D transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 3589520..3590611 Escherichia coli ATCC 8739 6066942 YP_001726230.1 CDS lacZ NC_010468.1 3590734 3593808 D forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 3590734..3593808 Escherichia coli ATCC 8739 6066946 YP_001726231.1 CDS lacY NC_010468.1 3593860 3595113 D lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 3593860..3595113 Escherichia coli ATCC 8739 6066950 YP_001726232.1 CDS lacA NC_010468.1 3595185 3595790 D transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 3595185..3595790 Escherichia coli ATCC 8739 6066969 YP_001726233.1 CDS cynX NC_010468.1 3595893 3597074 R MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; putative cyanate transporter complement(3595893..3597074) Escherichia coli ATCC 8739 6066972 YP_001726234.1 CDS EcolC_3285 NC_010468.1 3597080 3597550 R catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase complement(3597080..3597550) Escherichia coli ATCC 8739 6066978 YP_001726235.1 CDS EcolC_3286 NC_010468.1 3597581 3598240 R PFAM: carbonic anhydrase; KEGG: pen:PSEEN3600 carbonic anhydrase; carbonate dehydratase complement(3597581..3598240) Escherichia coli ATCC 8739 6066980 YP_001726236.1 CDS EcolC_3287 NC_010468.1 3598350 3599249 D controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR 3598350..3599249 Escherichia coli ATCC 8739 6066983 YP_001726237.1 CDS EcolC_3288 NC_010468.1 3599586 3600869 R Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase complement(3599586..3600869) Escherichia coli ATCC 8739 6066989 YP_001726238.1 CDS codB NC_010468.1 3600859 3602118 R TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: sec:SC3271 putative purine-cytosine permease; cytosine permease complement(3600859..3602118) Escherichia coli ATCC 8739 6066992 YP_001726239.1 CDS prpE NC_010468.1 3602542 3604428 R catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase complement(3602542..3604428) Escherichia coli ATCC 8739 6066997 YP_001726240.1 CDS prpD NC_010468.1 3604468 3605919 R functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase complement(3604468..3605919) Escherichia coli ATCC 8739 6065087 YP_001726241.1 CDS EcolC_3292 NC_010468.1 3605953 3607122 R catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase complement(3605953..3607122) Escherichia coli ATCC 8739 6067028 YP_001726242.1 CDS prpB NC_010468.1 3607469 3608359 R catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase complement(3607469..3608359) Escherichia coli ATCC 8739 6067033 YP_001726243.1 CDS EcolC_3294 NC_010468.1 3608598 3610184 D KEGG: cko:CKO_02831 hypothetical protein; TIGRFAM: propionate catabolism operon regulatory protein PrpR; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; Propionate catabolism activator domain protein; SMART: AAA ATPase; Fis family proprionate catabolism activator 3608598..3610184 Escherichia coli ATCC 8739 6067058 YP_001726244.1 CDS EcolC_3295 NC_010468.1 3610282 3610557 R PFAM: protein of unknown function DUF1471; KEGG: cko:CKO_02832 hypothetical protein; hypothetical protein complement(3610282..3610557) Escherichia coli ATCC 8739 6064779 YP_001726245.1 CDS EcolC_3296 NC_010468.1 3610704 3611375 D TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ssn:SSON_0302 putative cytochrome subunit of dehydrogenase; homoserine/threonine efflux pump 3610704..3611375 Escherichia coli ATCC 8739 6067068 YP_001726246.1 CDS EcolC_3297 NC_010468.1 3612050 3612865 R KEGG: ssn:SSON_0306 hypothetical protein; hypothetical protein complement(3612050..3612865) Escherichia coli ATCC 8739 6067075 YP_001726247.1 CDS EcolC_3298 NC_010468.1 3613108 3614157 R PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_0308 putative oxidoreductase; alcohol dehydrogenase complement(3613108..3614157) Escherichia coli ATCC 8739 6067078 YP_001726248.1 CDS EcolC_3299 NC_010468.1 3614534 3615916 R metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; putative deaminase complement(3614534..3615916) Escherichia coli ATCC 8739 6066353 YP_001726249.1 CDS EcolC_3300 NC_010468.1 3615926 3616876 R PFAM: aspartate/glutamate/uridylate kinase; KEGG: ssn:SSON_0310 putative kinase; putative carbamate kinase complement(3615926..3616876) Escherichia coli ATCC 8739 6067085 YP_001726250.1 CDS EcolC_3301 NC_010468.1 3616952 3617248 R hypothetical protein complement(3616952..3617248) Escherichia coli ATCC 8739 6067087 YP_001726251.1 CDS EcolC_3302 NC_010468.1 3617298 3618716 R PFAM: protein of unknown function DUF1116; KEGG: ssn:SSON_0311 hypothetical protein; hypothetical protein complement(3617298..3618716) Escherichia coli ATCC 8739 6067088 YP_001726252.1 CDS EcolC_3303 NC_010468.1 3618716 3620263 R PFAM: FdrA family protein; KEGG: ssn:SSON_0312 putative oxidoreductase subunit; FdrA family protein complement(3618716..3620263) Escherichia coli ATCC 8739 6067099 YP_001726253.1 CDS EcolC_3304 NC_010468.1 3620253 3621116 R KEGG: ssn:SSON_0313 hypothetical protein; hypothetical protein complement(3620253..3621116) Escherichia coli ATCC 8739 6067102 YP_001726254.1 CDS EcolC_3305 NC_010468.1 3621156 3621761 R PFAM: Ankyrin; KEGG: ent:Ent638_3145 ankyrin; ankyrin complement(3621156..3621761) Escherichia coli ATCC 8739 6067129 YP_001726255.1 CDS EcolC_3306 NC_010468.1 3622019 3622516 D PFAM: protein of unknown function DUF1097; KEGG: ctc:CTC01779 glutathione-regulated potassium-efflux system protein; hypothetical protein 3622019..3622516 Escherichia coli ATCC 8739 6067131 YP_001726256.1 CDS EcolC_3307 NC_010468.1 3622608 3623540 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ent:Ent638_3146 transcriptional regulator, LysR family; LysR family transcriptional regulator 3622608..3623540 Escherichia coli ATCC 8739 6067142 YP_001726257.1 CDS EcolC_3308 NC_010468.1 3623582 3624670 R PFAM: regulatory protein LuxR; EAL domain protein; KEGG: aha:AHA_3485 Rtn protein; diguanylate phosphodiesterase complement(3623582..3624670) Escherichia coli ATCC 8739 6067063 YP_001726258.1 CDS EcolC_3309 NC_010468.1 3625545 3627578 R proton-motive-force-driven choline transporter; choline transport protein BetT complement(3625545..3627578) Escherichia coli ATCC 8739 6067154 YP_001726259.1 CDS EcolC_3310 NC_010468.1 3627707 3628294 D HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 3627707..3628294 Escherichia coli ATCC 8739 6066404 YP_001726260.1 CDS EcolC_3311 NC_010468.1 3628308 3629780 D catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 3628308..3629780 Escherichia coli ATCC 8739 6067157 YP_001726261.1 CDS EcolC_3312 NC_010468.1 3629794 3631464 D catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 3629794..3631464 Escherichia coli ATCC 8739 6065713 YP_001726262.1 CDS EcolC_3313 NC_010468.1 3631677 3632345 D KEGG: sfv:SFV_0321 hypothetical protein; hypothetical protein 3631677..3632345 Escherichia coli ATCC 8739 6067159 YP_001726263.1 CDS EcolC_3314 NC_010468.1 3632588 3633283 R PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0319 putative transporter; hypothetical protein complement(3632588..3633283) Escherichia coli ATCC 8739 6066599 YP_001726264.1 CDS EcolC_3315 NC_010468.1 3633276 3634703 R TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0318 hypothetical protein; iron-sulfur cluster binding protein complement(3633276..3634703) Escherichia coli ATCC 8739 6067164 YP_001726265.1 CDS EcolC_3316 NC_010468.1 3634714 3635433 R PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: ssn:SSON_0318 putative dehydrogenase subunit; hypothetical protein complement(3634714..3635433) Escherichia coli ATCC 8739 6067177 YP_001726266.1 CDS EcolC_3317 NC_010468.1 3635960 3636814 R PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_0319 putative AraC-type regulatory protein; AraC family transcriptional regulator complement(3635960..3636814) Escherichia coli ATCC 8739 6067197 YP_001726267.1 CDS EcolC_3318 NC_010468.1 3637040 3638365 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 3637040..3638365 Escherichia coli ATCC 8739 6067200 YP_001726268.1 CDS EcolC_3319 NC_010468.1 3638722 3639315 D PFAM: protein of unknown function DUF417; KEGG: ssn:SSON_0322 hypothetical protein; hypothetical protein 3638722..3639315 Escherichia coli ATCC 8739 6067210 YP_001726269.1 CDS EcolC_3321 NC_010468.1 3639905 3640756 D PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: stm:STM1671 putative regulatory protein; AraC family transcriptional regulator 3639905..3640756 Escherichia coli ATCC 8739 6067215 YP_001726270.1 CDS EcolC_3322 NC_010468.1 3640896 3645152 R PFAM: Ig domain protein group 1 domain protein; KEGG: ypi:YpsIP31758_0608 putative invasin; Ig domain-containing protein complement(3640896..3645152) Escherichia coli ATCC 8739 6067220 YP_001726271.1 CDS rpmE2 NC_010468.1 3646730 3646996 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 3646730..3646996 Escherichia coli ATCC 8739 6067231 YP_001726272.1 CDS rpmJ NC_010468.1 3646996 3647136 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 3646996..3647136 Escherichia coli ATCC 8739 6067237 YP_001726273.1 CDS EcolC_3325 NC_010468.1 3648222 3648764 D PFAM: regulatory protein LuxR; KEGG: sbo:SBO_0225 putative regulator; LuxR family transcriptional regulator 3648222..3648764 Escherichia coli ATCC 8739 6066687 YP_001726274.1 CDS EcolC_3326 NC_010468.1 3648839 3649426 D KEGG: sbo:SBO_0226 hypothetical protein; hypothetical protein 3648839..3649426 Escherichia coli ATCC 8739 6067251 YP_001726275.1 CDS EcolC_3327 NC_010468.1 3649484 3650152 D KEGG: sbo:SBO_0227 hypothetical protein; hypothetical protein 3649484..3650152 Escherichia coli ATCC 8739 6067272 YP_001726276.1 CDS EcolC_3328 NC_010468.1 3650178 3652704 D KEGG: kpn:KPN_00293 putative enzyme; hypothetical protein join(3650178..3651461,3651463..3652704) Escherichia coli ATCC 8739 6067293 YP_001726277.1 CDS EcolC_3329 NC_010468.1 3652694 3654337 D KEGG: kpn:KPN_00294 putative receptor; putative receptor 3652694..3654337 Escherichia coli ATCC 8739 6067294 YP_001726278.1 CDS EcolC_3330 NC_010468.1 3654360 3655016 D KEGG: kpn:KPN_00295 hypothetical protein; hypothetical protein 3654360..3655016 Escherichia coli ATCC 8739 6067295 YP_001726279.1 CDS EcolC_3331 NC_010468.1 3655329 3655658 D PFAM: protein of unknown function UPF0153; KEGG: esa:ESA_01555 hypothetical protein; hypothetical protein 3655329..3655658 Escherichia coli ATCC 8739 6067301 YP_001726280.1 CDS EcolC_3332 NC_010468.1 3655906 3656520 R PFAM: protein of unknown function DUF1440; KEGG: ent:Ent638_2282 protein of unknown function DUF1440; hypothetical protein complement(3655906..3656520) Escherichia coli ATCC 8739 6066732 YP_001726281.1 CDS EcolC_3333 NC_010468.1 3656938 3657627 D PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: esa:ESA_04143 hypothetical protein; putative xanthine dehydrogenase iron-sulfur-binding subunit 3656938..3657627 Escherichia coli ATCC 8739 6067314 YP_001726282.1 CDS EcolC_3334 NC_010468.1 3657624 3658580 D PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: esa:ESA_04145 hypothetical protein; FAD-binding molybdopterin dehydrogenase 3657624..3658580 Escherichia coli ATCC 8739 6067317 YP_001726283.1 CDS EcolC_3335 NC_010468.1 3658577 3660775 D PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: esa:ESA_04146 hypothetical protein; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase 3658577..3660775 Escherichia coli ATCC 8739 6065177 YP_001726284.1 CDS EcolC_3336 NC_010468.1 3660785 3661741 D PFAM: protein of unknown function DUF182; KEGG: esa:ESA_04147 hypothetical protein; hypothetical protein 3660785..3661741 Escherichia coli ATCC 8739 6067324 YP_001726285.1 CDS EcolC_3337 NC_010468.1 3661720 3662130 D KEGG: smd:Smed_5891 transcriptional regulator, LysR family; hypothetical protein 3661720..3662130 Escherichia coli ATCC 8739 6067214 YP_001726286.1 CDS proA NC_010468.1 3662447 3663700 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(3662447..3663700) Escherichia coli ATCC 8739 6067335 YP_001726287.1 CDS EcolC_3339 NC_010468.1 3663712 3664815 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(3663712..3664815) Escherichia coli ATCC 8739 6067338 YP_001726288.1 CDS EcolC_3340 NC_010468.1 3665103 3666158 D PFAM: porin Gram-negative type; KEGG: sbo:SBO_0247 outer membrane pore protein E; outer membrane phosphoporin protein E 3665103..3666158 Escherichia coli ATCC 8739 6067357 YP_001726289.1 CDS EcolC_3341 NC_010468.1 3666197 3666598 R involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl complement(3666197..3666598) Escherichia coli ATCC 8739 6067358 YP_001726290.1 CDS frsA NC_010468.1 3666656 3667900 R forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein complement(3666656..3667900) Escherichia coli ATCC 8739 6067362 YP_001726291.1 CDS EcolC_3343 NC_010468.1 3667992 3668450 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(3667992..3668450) Escherichia coli ATCC 8739 6067366 YP_001726292.1 CDS EcolC_3344 NC_010468.1 3668711 3670168 D KEGG: sdy:SDY_0480 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; aminoacyl-histidine dipeptidase 3668711..3670168 Escherichia coli ATCC 8739 6067368 YP_001726293.1 CDS EcolC_3346 NC_010468.1 3670864 3671561 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(3670864..3671307,3671307..3671561)) Escherichia coli ATCC 8739 6067391 YP_001726294.1 CDS EcolC_3348 NC_010468.1 3671754 3672047 R TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: sfv:SFV_0298 hypothetical protein; putative antitoxin of the YafO-YafN toxin-antitoxin system complement(3671754..3672047) Escherichia coli ATCC 8739 6067398 YP_001726295.1 CDS EcolC_3349 NC_010468.1 3672099 3673154 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(3672099..3673154) Escherichia coli ATCC 8739 6067406 YP_001726296.1 CDS EcolC_3350 NC_010468.1 3673225 3674148 R PFAM: OmpA/MotB domain protein; KEGG: sdy:SDY_0484 putative motility protein; hypothetical protein complement(3673225..3674148) Escherichia coli ATCC 8739 6067409 YP_001726297.1 CDS EcolC_3351 NC_010468.1 3674151 3675014 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(3674151..3675014) Escherichia coli ATCC 8739 6067410 YP_001726298.1 CDS EcolC_3352 NC_010468.1 3675027 3675743 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(3675027..3675743) Escherichia coli ATCC 8739 6067414 YP_001726299.1 CDS EcolC_3353 NC_010468.1 3675763 3676230 R PFAM: flagellar basal body-associated protein FliL; KEGG: cvi:CV_2991 hypothetical protein; flagellar basal body-associated protein FliL complement(3675763..3676230) Escherichia coli ATCC 8739 6067429 YP_001726300.1 CDS EcolC_3354 NC_010468.1 3676238 3677299 R PFAM: flagellar hook-length control protein; KEGG: cko:CKO_02859 hypothetical protein; flagellar hook-length control protein complement(3676238..3677299) Escherichia coli ATCC 8739 6067432 YP_001726301.1 CDS EcolC_3355 NC_010468.1 3677296 3677607 R hypothetical protein complement(3677296..3677607) Escherichia coli ATCC 8739 6067434 YP_001726302.1 CDS EcolC_3356 NC_010468.1 3677612 3678004 R PFAM: flagellar protein FliS; KEGG: cko:CKO_02862 hypothetical protein; flagellar protein FliS complement(3677612..3678004) Escherichia coli ATCC 8739 6067437 YP_001726303.1 CDS EcolC_3357 NC_010468.1 3678027 3679343 R PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: vha:VIBHAR_04956 flagellar capping protein; flagellar hook-associated 2 domain-containing protein complement(3678027..3679343) Escherichia coli ATCC 8739 6067442 YP_001726304.1 CDS EcolC_3358 NC_010468.1 3679595 3680509 R PFAM: flagellin domain protein; KEGG: pmy:Pmen_0196 flagellin domain protein; flagellin domain-containing protein complement(3679595..3680509) Escherichia coli ATCC 8739 6067022 YP_001726305.1 CDS EcolC_3359 NC_010468.1 3680995 3681837 D PFAM: transcriptional regulator domain protein; KEGG: cko:CKO_02869 hypothetical protein; transcriptional regulator CadC 3680995..3681837 Escherichia coli ATCC 8739 6067445 YP_001726306.1 CDS EcolC_3360 NC_010468.1 3681896 3682873 R KEGG: cko:CKO_02871 hypothetical protein; hypothetical protein complement(3681896..3682873) Escherichia coli ATCC 8739 6067455 YP_001726307.1 CDS EcolC_3361 NC_010468.1 3682890 3683819 R TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: pmy:Pmen_0216 flagellar hook-associated protein 3; flagellar hook-associated protein 3 complement(3682890..3683819) Escherichia coli ATCC 8739 6064975 YP_001726308.1 CDS EcolC_3362 NC_010468.1 3683834 3685210 R TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cko:CKO_02873 hypothetical protein; flagellar hook-associated protein FlgK complement(3683834..3685210) Escherichia coli ATCC 8739 6067459 YP_001726309.1 CDS EcolC_3363 NC_010468.1 3685400 3685699 R KEGG: yps:YPTB3332 putative flagellar protein; rod binding protein-like protein complement(3685400..3685699) Escherichia coli ATCC 8739 6067463 YP_001726310.1 CDS flgI NC_010468.1 3685699 3686799 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(3685699..3686799) Escherichia coli ATCC 8739 6067464 YP_001726311.1 CDS flgH NC_010468.1 3686814 3687479 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH; flagellar basal body L-ring protein complement(3686814..3687479) Escherichia coli ATCC 8739 6066213 YP_001726312.1 CDS flgG NC_010468.1 3687682 3688467 R makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG complement(3687682..3688467) Escherichia coli ATCC 8739 6067467 YP_001726313.1 CDS flgF NC_010468.1 3688546 3689283 R FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF complement(3688546..3689283) Escherichia coli ATCC 8739 6067471 YP_001726314.1 CDS EcolC_3368 NC_010468.1 3689283 3690485 R PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: pmy:Pmen_0209 flagellar basal body FlaE domain protein; flagellar basal body FlaE domain-containing protein complement(3689283..3690485) Escherichia coli ATCC 8739 6064903 YP_001726315.1 CDS EcolC_3369 NC_010468.1 3690628 3691341 R PFAM: flagellar hook capping protein; KEGG: cko:CKO_02880 hypothetical protein; flagellar hook capping protein complement(3690628..3691341) Escherichia coli ATCC 8739 6067477 YP_001726316.1 CDS flgC NC_010468.1 3691341 3691772 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar basal body rod protein FlgC complement(3691341..3691772) Escherichia coli ATCC 8739 6067494 YP_001726317.1 CDS EcolC_3371 NC_010468.1 3691775 3692110 R TIGRFAM: flagellar basal-body rod protein FlgB; KEGG: cko:CKO_02882 hypothetical protein; flagellar basal-body rod protein FlgB complement(3691775..3692110) Escherichia coli ATCC 8739 6066135 YP_001726318.1 CDS EcolC_3372 NC_010468.1 3692192 3692929 D TIGRFAM: flagella basal body P-ring formation protein FlgA; PFAM: SAF domain protein; KEGG: cko:CKO_02883 hypothetical protein; flagella basal body P-ring formation protein FlgA 3692192..3692929 Escherichia coli ATCC 8739 6067497 YP_001726319.1 CDS EcolC_3373 NC_010468.1 3693010 3693288 D PFAM: Anti-sigma-28 factor FlgM family protein; anti-sigma-28 factor FlgM 3693010..3693288 Escherichia coli ATCC 8739 6067500 YP_001726320.1 CDS EcolC_3374 NC_010468.1 3693301 3693729 D KEGG: cko:CKO_02886 hypothetical protein; hypothetical protein 3693301..3693729 Escherichia coli ATCC 8739 6067511 YP_001726321.1 CDS EcolC_3375 NC_010468.1 3693856 3694785 D KEGG: cko:CKO_02891 hypothetical protein; hypothetical protein 3693856..3694785 Escherichia coli ATCC 8739 6067512 YP_001726322.1 CDS EcolC_3376 NC_010468.1 3694964 3697408 D PFAM: glycosyl transferase family 2; KEGG: cko:CKO_02892 hypothetical protein; glycosyl transferase family protein 3694964..3697408 Escherichia coli ATCC 8739 6067521 YP_001726323.1 CDS EcolC_3377 NC_010468.1 3697526 3697921 R TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: nca:Noca_1691 cytidyltransferase-related domain; cytidyltransferase-like protein complement(3697526..3697921) Escherichia coli ATCC 8739 6067529 YP_001726324.1 CDS EcolC_3378 NC_010468.1 3697924 3698358 R TIGRFAM: flagellar export protein FliJ; KEGG: cko:CKO_02893 hypothetical protein; flagellar export protein FliJ complement(3697924..3698358) Escherichia coli ATCC 8739 6067540 YP_001726325.1 CDS EcolC_3379 NC_010468.1 3698361 3699698 R KEGG: cko:CKO_02894 hypothetical protein; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase; FliI/YscN family ATPase complement(3698361..3699698) Escherichia coli ATCC 8739 6067543 YP_001726326.1 CDS fliH NC_010468.1 3699691 3700401 R binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H complement(3699691..3700401) Escherichia coli ATCC 8739 6067562 YP_001726327.1 CDS fliG NC_010468.1 3700405 3701415 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G complement(3700405..3701415) Escherichia coli ATCC 8739 6067565 YP_001726328.1 CDS fliF NC_010468.1 3701393 3703039 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar MS-ring protein complement(3701393..3703039) Escherichia coli ATCC 8739 6067566 YP_001726329.1 CDS EcolC_3383 NC_010468.1 3703044 3703385 R PFAM: flagellar hook-basal body complex protein FliE; KEGG: vpa:VPA1537 putative flagellar hook-basal body complex protein; flagellar hook-basal body complex protein FliE complement(3703044..3703385) Escherichia coli ATCC 8739 6067567 YP_001726330.1 CDS EcolC_3384 NC_010468.1 3703400 3704386 R PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; KEGG: ypi:YpsIP31758_0629 sigma-54 dependent transcriptional regulator; putative sigma-54 specific transcriptional regulator complement(3703400..3704386) Escherichia coli ATCC 8739 6067568 YP_001726331.1 CDS EcolC_3385 NC_010468.1 3704773 3705624 D PFAM: surface presentation of antigens (SPOA) protein; KEGG: cko:CKO_02900 hypothetical protein; surface presentation of antigens (SPOA) protein 3704773..3705624 Escherichia coli ATCC 8739 6067577 YP_001726332.1 CDS EcolC_3386 NC_010468.1 3705617 3705988 D PFAM: surface presentation of antigens (SPOA) protein; KEGG: cko:CKO_02901 hypothetical protein; surface presentation of antigens (SPOA) protein 3705617..3705988 Escherichia coli ATCC 8739 6067581 YP_001726333.1 CDS fliP NC_010468.1 3705985 3706737 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 3705985..3706737 Escherichia coli ATCC 8739 6067586 YP_001726334.1 CDS EcolC_3388 NC_010468.1 3706740 3707012 D PFAM: export protein FliQ family 3; KEGG: yps:YPTB3354 putative flagellar assembly/export protein, fliQ; export protein FliQ 3706740..3707012 Escherichia coli ATCC 8739 6067607 YP_001726335.1 CDS EcolC_3389 NC_010468.1 3707014 3707796 D TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: cko:CKO_02904 hypothetical protein; flagellar biosynthetic protein FliR 3707014..3707796 Escherichia coli ATCC 8739 6067608 YP_001726336.1 CDS flhB NC_010468.1 3707786 3708925 D membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 3707786..3708925 Escherichia coli ATCC 8739 6067612 YP_001726337.1 CDS EcolC_3391 NC_010468.1 3708909 3711002 D PFAM: type III secretion FHIPEP protein; KEGG: ssn:SSON_0273 flagellar biosynthesis; type III secretion FHIPEP protein 3708909..3711002 Escherichia coli ATCC 8739 6067614 YP_001726338.1 CDS EcolC_3392 NC_010468.1 3711218 3711715 R KEGG: ssn:SSON_0271 hypothetical protein; hypothetical protein complement(3711218..3711715) Escherichia coli ATCC 8739 6067618 YP_001726339.1 CDS EcolC_3393 NC_010468.1 3711891 3712517 R PFAM: NLP/P60 protein; KEGG: ssn:SSON_0269 putative lipoprotein; NLP/P60 protein complement(3711891..3712517) Escherichia coli ATCC 8739 6067623 YP_001726340.1 CDS EcolC_3394 NC_010468.1 3712850 3713110 D TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: ssn:SSON_0268 damage-inducible protein J; addiction module antitoxin 3712850..3713110 Escherichia coli ATCC 8739 6067634 YP_001726341.1 CDS EcolC_3395 NC_010468.1 3713113 3713391 D TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sdy:SDY_0251 hypothetical protein; addiction module antitoxin 3713113..3713391 Escherichia coli ATCC 8739 6067638 YP_001726342.1 CDS EcolC_3396 NC_010468.1 3713547 3714287 D PFAM: protein of unknown function DUF949; KEGG: sdy:SDY_0250 hypothetical protein; hypothetical protein 3713547..3714287 Escherichia coli ATCC 8739 6067655 YP_001726343.1 CDS EcolC_3397 NC_010468.1 3714258 3715025 R PFAM: glutamine amidotransferase class-II; KEGG: sdy:SDY_0249 putative amidotransferase; glutamine amidotransferase complement(3714258..3715025) Escherichia coli ATCC 8739 6067660 YP_001726344.1 CDS gmhA NC_010468.1 3715231 3715809 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(3715231..3715809) Escherichia coli ATCC 8739 6067666 YP_001726345.1 CDS fadE NC_010468.1 3716049 3718493 D functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 3716049..3718493 Escherichia coli ATCC 8739 6067673 YP_001726346.1 CDS EcolC_3400 NC_010468.1 3718536 3719009 R inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor complement(3718536..3719009) Escherichia coli ATCC 8739 6067676 YP_001726347.1 CDS EcolC_3401 NC_010468.1 3719163 3719933 D PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbo:SBO_0208 putative amidase-type enzyme; hypothetical protein 3719163..3719933 Escherichia coli ATCC 8739 6067679 YP_001726348.1 CDS EcolC_3404 NC_010468.1 3722286 3722861 R KEGG: dac:Daci_2522 conserved hypothetical protein; hypothetical protein complement(3722286..3722861) Escherichia coli ATCC 8739 6067701 YP_001726349.1 CDS EcolC_3405 NC_010468.1 3723179 3723463 D PFAM: transposase IS3/IS911 family protein; KEGG: spe:Spro_0361 transposase IS3/IS911 family protein; transposase IS3/IS911 family protein 3723179..3723463 Escherichia coli ATCC 8739 6067702 YP_001726350.1 CDS EcolC_3406 NC_010468.1 3723505 3724314 D PFAM: Integrase catalytic region; KEGG: psa:PST_1859 transposase, IS3 family; integrase catalytic subunit 3723505..3724314 Escherichia coli ATCC 8739 6067703 YP_001726351.1 CDS EcolC_3407 NC_010468.1 3724377 3724733 D PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_4359 ISEhe3 orfA; transposase IS3/IS911 family protein 3724377..3724733 Escherichia coli ATCC 8739 6067704 YP_001726352.1 CDS EcolC_3408 NC_010468.1 3724690 3725652 D KEGG: bxe:Bxe_C0741 putative transposase IS30; putative transposase IS30 3724690..3725652 Escherichia coli ATCC 8739 6067712 YP_001726353.1 CDS EcolC_3409 NC_010468.1 3725926 3726744 D PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2; integrase catalytic subunit 3725926..3726744 Escherichia coli ATCC 8739 6067719 YP_001726354.1 CDS EcolC_3410 NC_010468.1 3726857 3727291 R KEGG: kpn:KPN_pKPN3p05933 probable copper-binding protein; putative copper-binding protein complement(3726857..3727291) Escherichia coli ATCC 8739 6067732 YP_001726355.1 CDS EcolC_3411 NC_010468.1 3727509 3728909 R TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: esa:ESA_04254 hypothetical protein; heavy metal sensor signal transduction histidine kinase complement(3727509..3728909) Escherichia coli ATCC 8739 6067733 YP_001726356.1 CDS EcolC_3412 NC_010468.1 3728906 3729586 R TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: kpn:KPN_pKPN3p05937 transcriptional regulatory protein PcoR; two component heavy metal response transcriptional regulator complement(3728906..3729586) Escherichia coli ATCC 8739 6067738 YP_001726357.1 CDS EcolC_3413 NC_010468.1 3729641 3730570 R PFAM: copper resistance D domain protein; KEGG: kpn:KPN_pKPN3p05938 copper resistant protein PcoD; copper resistance D domain-containing protein complement(3729641..3730570) Escherichia coli ATCC 8739 6066087 YP_001726358.1 CDS EcolC_3414 NC_010468.1 3730575 3730955 R PFAM: copper resistance protein CopC; KEGG: kpn:KPN_pKPN3p05939 copper resistant protein PcoC; copper resistance protein CopC complement(3730575..3730955) Escherichia coli ATCC 8739 6067751 YP_001726359.1 CDS EcolC_3415 NC_010468.1 3730995 3731891 R PFAM: copper resistance B precursor; KEGG: kpn:KPN_pKPN3p05940 copper resistant protein PcoB; copper resistance B complement(3730995..3731891) Escherichia coli ATCC 8739 6067753 YP_001726360.1 CDS EcolC_3416 NC_010468.1 3731891 3733708 R TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: kpn:KPN_pKPN3p05941 copper resistant protein PcoA; CopA family copper resistance protein complement(3731891..3733708) Escherichia coli ATCC 8739 6067764 YP_001726361.1 CDS EcolC_3417 NC_010468.1 3733943 3734392 D KEGG: shn:Shewana3_4304 hypothetical protein; hypothetical protein 3733943..3734392 Escherichia coli ATCC 8739 6067769 YP_001726362.1 CDS EcolC_3418 NC_010468.1 3734681 3735418 D PFAM: peptidase M23B; KEGG: shn:Shewana3_4303 peptidase M23B; peptidase M23B 3734681..3735418 Escherichia coli ATCC 8739 6067773 YP_001726363.1 CDS EcolC_3419 NC_010468.1 3735452 3735649 R KEGG: esa:ESA_04246 hypothetical protein; hypothetical protein complement(3735452..3735649) Escherichia coli ATCC 8739 6067789 YP_001726364.1 CDS EcolC_3420 NC_010468.1 3735690 3738137 R KEGG: spc:Sputcn32_0264 heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein; heavy metal translocating P-type ATPase complement(3735690..3738137) Escherichia coli ATCC 8739 6067798 YP_001726365.1 CDS EcolC_3421 NC_010468.1 3738264 3738704 R PFAM: protein of unknown function DUF411; KEGG: kpn:KPN_pKPN3p05946 exported protein (silver resistance); hypothetical protein complement(3738264..3738704) Escherichia coli ATCC 8739 6067820 YP_001726366.1 CDS EcolC_3422 NC_010468.1 3738791 3741937 R TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: esa:ESA_04242 hypothetical protein; CzcA family heavy metal efflux protein complement(3738791..3741937) Escherichia coli ATCC 8739 6067821 YP_001726367.1 CDS EcolC_3423 NC_010468.1 3741948 3743240 R with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB complement(3741948..3743240) Escherichia coli ATCC 8739 6067827 YP_001726368.1 CDS EcolC_3424 NC_010468.1 3743354 3743707 R KEGG: spc:Sputcn32_0260 periplasmic copper-binding protein; copper-binding protein complement(3743354..3743707) Escherichia coli ATCC 8739 6067829 YP_001726369.1 CDS EcolC_3425 NC_010468.1 3743736 3745121 R with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC complement(3743736..3745121) Escherichia coli ATCC 8739 6067839 YP_001726370.1 CDS EcolC_3426 NC_010468.1 3745311 3745991 D response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 3745311..3745991 Escherichia coli ATCC 8739 6067858 YP_001726371.1 CDS EcolC_3427 NC_010468.1 3745984 3747459 D KEGG: esa:ESA_04237 hypothetical protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; sensor kinase CusS 3745984..3747459 Escherichia coli ATCC 8739 6067860 YP_001726372.1 CDS EcolC_3428 NC_010468.1 3747710 3748141 D KEGG: kpn:KPN_pKPN3p05952 silver binding protein precursor SilE; silver binding protein SilE 3747710..3748141 Escherichia coli ATCC 8739 6067865 YP_001726373.1 CDS EcolC_3430 NC_010468.1 3749726 3750076 D PFAM: protein of unknown function DUF305; KEGG: esa:ESA_04235 hypothetical protein; hypothetical protein 3749726..3750076 Escherichia coli ATCC 8739 6067875 YP_001726374.1 CDS EcolC_3432 NC_010468.1 3751949 3752605 R PFAM: putative transposase YhgA family protein; KEGG: stm:PSLT051 putative cytoplasmic protein; putative transposase YhgA family protein complement(3751949..3752605) Escherichia coli ATCC 8739 6067887 YP_001726375.1 CDS EcolC_3433 NC_010468.1 3752875 3753750 D PFAM: GTP-binding protein HSR1-related; KEGG: ypi:YpsIP31758_0759 putative GTPase; HSR1-like GTP-binding protein 3752875..3753750 Escherichia coli ATCC 8739 6067889 YP_001726376.1 CDS EcolC_3434 NC_010468.1 3754011 3754724 D KEGG: ypi:YpsIP31758_0758 transcriptional regulator; transcriptional regulator 3754011..3754724 Escherichia coli ATCC 8739 6067890 YP_001726377.1 CDS EcolC_3435 NC_010468.1 3754721 3755356 D KEGG: ypi:YpsIP31758_0757 hypothetical protein; hypothetical protein 3754721..3755356 Escherichia coli ATCC 8739 6067891 YP_001726378.1 CDS EcolC_3436 NC_010468.1 3755392 3755844 D hypothetical protein 3755392..3755844 Escherichia coli ATCC 8739 6067896 YP_001726379.1 CDS EcolC_3437 NC_010468.1 3755841 3756293 D hypothetical protein 3755841..3756293 Escherichia coli ATCC 8739 6067900 YP_001726380.1 CDS EcolC_3438 NC_010468.1 3756356 3756898 D KEGG: ypi:YpsIP31758_0756 hypothetical protein; hypothetical protein 3756356..3756898 Escherichia coli ATCC 8739 6067902 YP_001726381.1 CDS EcolC_3439 NC_010468.1 3756957 3757409 D KEGG: sfx:S3197 hypothetical protein; hypothetical protein 3756957..3757409 Escherichia coli ATCC 8739 6067903 YP_001726382.1 CDS EcolC_3440 NC_010468.1 3757486 3757719 D KEGG: ypp:YPDSF_4148 hypothetical protein; hypothetical protein 3757486..3757719 Escherichia coli ATCC 8739 6067918 YP_001726383.1 CDS EcolC_3441 NC_010468.1 3757839 3758657 D PFAM: protein of unknown function DUF932; KEGG: sfx:S3199 hypothetical protein; hypothetical protein 3757839..3758657 Escherichia coli ATCC 8739 6067923 YP_001726384.1 CDS EcolC_3442 NC_010468.1 3758925 3759395 D PFAM: Antirestriction protein; KEGG: sdy:SDY_4589 hypothetical protein; antirestriction protein 3758925..3759395 Escherichia coli ATCC 8739 6067926 YP_001726385.1 CDS EcolC_3443 NC_010468.1 3759407 3759886 D PFAM: DNA repair protein RadC; KEGG: yps:YPTB3868 hypothetical protein; DNA repair protein RadC 3759407..3759886 Escherichia coli ATCC 8739 6067928 YP_001726386.1 CDS EcolC_3444 NC_010468.1 3759907 3760128 D PFAM: protein of unknown function DUF987; KEGG: sfx:S3202 hypothetical protein; hypothetical protein 3759907..3760128 Escherichia coli ATCC 8739 6067929 YP_001726387.1 CDS EcolC_3445 NC_010468.1 3760152 3760511 D PFAM: YagBYeeUYfjZ family protein; KEGG: sfx:S3203 putative structural protein; hypothetical protein 3760152..3760511 Escherichia coli ATCC 8739 6067931 YP_001726388.1 CDS EcolC_3446 NC_010468.1 3760562 3760939 D PFAM: protein of unknown function DUF1219; KEGG: sdy:SDY_1009 hypothetical protein; hypothetical protein 3760562..3760939 Escherichia coli ATCC 8739 6067939 YP_001726389.1 CDS EcolC_3447 NC_010468.1 3760936 3761427 D KEGG: sdy:SDY_1008 hypothetical protein; hypothetical protein 3760936..3761427 Escherichia coli ATCC 8739 6067942 YP_001726390.1 CDS EcolC_3448 NC_010468.1 3761459 3761662 D PFAM: protein of unknown function DUF957; KEGG: sfl:SF3001 hypothetical protein; hypothetical protein 3761459..3761662 Escherichia coli ATCC 8739 6067946 YP_001726391.1 CDS EcolC_3450 NC_010468.1 3762929 3763669 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(3762929..3763669) Escherichia coli ATCC 8739 6067968 YP_001726392.1 CDS rnhA NC_010468.1 3763725 3764192 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 3763725..3764192 Escherichia coli ATCC 8739 6067989 YP_001726393.1 CDS EcolC_3452 NC_010468.1 3764189 3764911 R PFAM: Methyltransferase type 11; KEGG: ssn:SSON_0227 hypothetical protein; type 11 methyltransferase complement(3764189..3764911) Escherichia coli ATCC 8739 6067994 YP_001726394.1 CDS EcolC_3453 NC_010468.1 3764945 3765700 D catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 3764945..3765700 Escherichia coli ATCC 8739 6067997 YP_001726395.1 CDS mltD NC_010468.1 3765772 3767130 D catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 3765772..3767130 Escherichia coli ATCC 8739 6067999 YP_001726396.1 CDS EcolC_3455 NC_010468.1 3767178 3767801 R PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ssn:SSON_0224 putative biotin synthesis protein; type 11 methyltransferase complement(3767178..3767801) Escherichia coli ATCC 8739 6068017 YP_001726397.1 CDS EcolC_3456 NC_010468.1 3767805 3768605 R PFAM: Endonuclease/exonuclease/phosphatase; KEGG: sbo:SBO_0198 hypothetical protein; hypothetical protein complement(3767805..3768605) Escherichia coli ATCC 8739 6068025 YP_001726398.1 CDS EcolC_3457 NC_010468.1 3768846 3769760 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ssn:SSON_0222 putative transcriptional regulator LysR-type; LysR family transcriptional regulator 3768846..3769760 Escherichia coli ATCC 8739 6068027 YP_001726399.1 CDS dkgB NC_010468.1 3769757 3770560 R catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B complement(3769757..3770560) Escherichia coli ATCC 8739 6068048 YP_001726400.1 CDS EcolC_3459 NC_010468.1 3776414 3776986 R Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase complement(3776414..3776986) Escherichia coli ATCC 8739 6068154 YP_001726401.1 CDS metN NC_010468.1 3777174 3778205 D part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 3777174..3778205 Escherichia coli ATCC 8739 6068159 YP_001726402.1 CDS EcolC_3461 NC_010468.1 3778198 3778851 D part of the MetNIQ methionine uptake system; DL-methionine transporter permease 3778198..3778851 Escherichia coli ATCC 8739 6068161 YP_001726403.1 CDS metQ NC_010468.1 3778891 3779706 D TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sbo:SBO_0186 putative lipoprotein; DL-methionine transporter substrate-binding subunit 3778891..3779706 Escherichia coli ATCC 8739 6068182 YP_001726404.1 CDS rcsF NC_010468.1 3779824 3780228 D KEGG: sdy:SDY_0215 regulator in colanic acid synthesis; outer membrane lipoprotein 3779824..3780228 Escherichia coli ATCC 8739 6068187 YP_001726405.1 CDS EcolC_3464 NC_010468.1 3780225 3780932 D PFAM: protein of unknown function UPF0066; KEGG: ssn:SSON_0209 hypothetical protein; hypothetical protein 3780225..3780932 Escherichia coli ATCC 8739 6068188 YP_001726406.1 CDS EcolC_3465 NC_010468.1 3781044 3782762 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 3781044..3782762 Escherichia coli ATCC 8739 6068198 YP_001726407.1 CDS EcolC_3466 NC_010468.1 3782816 3783640 D KEGG: ssn:SSON_0207 hypothetical protein; hypothetical protein 3782816..3783640 Escherichia coli ATCC 8739 6068203 YP_001726408.1 CDS EcolC_3467 NC_010468.1 3783814 3784524 R PFAM: copper resistance lipoprotein NlpE; KEGG: ssn:SSON_0206 copper homeostasis protein; lipoprotein involved with copper homeostasis and adhesion complement(3783814..3784524) Escherichia coli ATCC 8739 6068207 YP_001726409.1 CDS EcolC_3468 NC_010468.1 3784538 3784960 R PFAM: Class I peptide chain release factor; KEGG: sbo:SBO_0180 hypothetical protein; peptidyl-tRNA hydrolase domain-containing protein complement(3784538..3784960) Escherichia coli ATCC 8739 6068210 YP_001726410.1 CDS EcolC_3469 NC_010468.1 3784957 3785502 R PFAM: YaeQ family protein; KEGG: sbo:SBO_0179 hypothetical protein; YaeQ family protein complement(3784957..3785502) Escherichia coli ATCC 8739 6068225 YP_001726411.1 CDS EcolC_3470 NC_010468.1 3785668 3785868 D PFAM: protein of unknown function UPF0253; KEGG: sdy:SDY_0208 putative cytoplasmic protein; hypothetical protein 3785668..3785868 Escherichia coli ATCC 8739 6068244 YP_001726412.1 CDS EcolC_3471 NC_010468.1 3785855 3786115 D Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 3785855..3786115 Escherichia coli ATCC 8739 6068249 YP_001726413.1 CDS tilS NC_010468.1 3786164 3787462 R Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase complement(3786164..3787462) Escherichia coli ATCC 8739 6068250 YP_001726414.1 CDS EcolC_3473 NC_010468.1 3787527 3787916 R PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sbo:SBO_0175 hypothetical protein; hypothetical protein complement(3787527..3787916) Escherichia coli ATCC 8739 6068259 YP_001726415.1 CDS EcolC_3474 NC_010468.1 3787973 3790114 R PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ssn:SSON_0199 lysine decarboxylase 2, constitutive; lysine decarboxylase complement(3787973..3790114) Escherichia coli ATCC 8739 6068263 YP_001726416.1 CDS EcolC_3475 NC_010468.1 3790213 3791172 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(3790213..3791172) Escherichia coli ATCC 8739 6068277 YP_001726417.1 CDS dnaE NC_010468.1 3791185 3794667 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(3791185..3794667) Escherichia coli ATCC 8739 6068282 YP_001726418.1 CDS rnhB NC_010468.1 3794704 3795300 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(3794704..3795300) Escherichia coli ATCC 8739 6068291 YP_001726419.1 CDS lpxB NC_010468.1 3795297 3796445 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(3795297..3796445) Escherichia coli ATCC 8739 6068300 YP_001726420.1 CDS EcolC_3479 NC_010468.1 3796445 3797233 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(3796445..3797233) Escherichia coli ATCC 8739 6068311 YP_001726421.1 CDS fabZ NC_010468.1 3797237 3797692 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(3797237..3797692) Escherichia coli ATCC 8739 6068317 YP_001726422.1 CDS lpxD NC_010468.1 3797797 3798822 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(3797797..3798822) Escherichia coli ATCC 8739 6068327 YP_001726423.1 CDS EcolC_3482 NC_010468.1 3798826 3799311 R PFAM: outer membrane chaperone Skp (OmpH); KEGG: sdy:SDY_0194 histone-like protein; periplasmic chaperone complement(3798826..3799311) Escherichia coli ATCC 8739 6068342 YP_001726424.1 CDS EcolC_3483 NC_010468.1 3799433 3801865 R part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT complement(3799433..3801865) Escherichia coli ATCC 8739 6068356 YP_001726425.1 CDS EcolC_3484 NC_010468.1 3801895 3803247 R catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP complement(3801895..3803247) Escherichia coli ATCC 8739 6068364 YP_001726426.1 CDS cdsA NC_010468.1 3803259 3804116 R catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase complement(3803259..3804116) Escherichia coli ATCC 8739 6068365 YP_001726427.1 CDS EcolC_3486 NC_010468.1 3804129 3804890 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(3804129..3804890) Escherichia coli ATCC 8739 6068380 YP_001726428.1 CDS EcolC_3487 NC_010468.1 3805076 3806272 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(3805076..3806272) Escherichia coli ATCC 8739 6068398 YP_001726429.1 CDS frr NC_010468.1 3806364 3806921 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(3806364..3806921) Escherichia coli ATCC 8739 6068401 YP_001726430.1 CDS pyrH NC_010468.1 3807213 3807938 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(3807213..3807938) Escherichia coli ATCC 8739 6068406 YP_001726431.1 CDS tsf NC_010468.1 3808085 3808936 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(3808085..3808936) Escherichia coli ATCC 8739 6068416 YP_001726432.1 CDS rpsB NC_010468.1 3809194 3809919 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(3809194..3809919) Escherichia coli ATCC 8739 6068424 YP_001726433.1 CDS EcolC_3492 NC_010468.1 3810287 3811081 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 3810287..3811081 Escherichia coli ATCC 8739 6068434 YP_001726434.1 CDS EcolC_3493 NC_010468.1 3811143 3813815 D catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 3811143..3813815 Escherichia coli ATCC 8739 6068446 YP_001726435.1 CDS dapD NC_010468.1 3813846 3814670 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 3813846..3814670 Escherichia coli ATCC 8739 6068455 YP_001726436.1 CDS EcolC_3495 NC_010468.1 3814793 3815536 D PFAM: metallophosphoesterase; KEGG: sbo:SBO_0153 hypothetical protein; phosphodiesterase YaeI 3814793..3815536 Escherichia coli ATCC 8739 6068463 YP_001726437.1 CDS EcolC_3496 NC_010468.1 3815698 3816084 D KEGG: sdy:SDY_0181 putative structural protein; hypothetical protein 3815698..3816084 Escherichia coli ATCC 8739 6068478 YP_001726438.1 CDS EcolC_3497 NC_010468.1 3816173 3817330 R regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR complement(3816173..3817330) Escherichia coli ATCC 8739 6068483 YP_001726439.1 CDS EcolC_3498 NC_010468.1 3817485 3818909 R protease Do; required at high temperature; degrades damaged proteins; serine endoprotease complement(3817485..3818909) Escherichia coli ATCC 8739 6068491 YP_001726440.1 CDS dgt NC_010468.1 3819039 3820556 R forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase complement(3819039..3820556) Escherichia coli ATCC 8739 6068497 YP_001726441.1 CDS EcolC_3500 NC_010468.1 3820640 3821338 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 3820640..3821338 Escherichia coli ATCC 8739 6068499 YP_001726442.1 CDS EcolC_3501 NC_010468.1 3821331 3822131 D solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 3821331..3822131 Escherichia coli ATCC 8739 6068502 YP_001726443.1 CDS EcolC_3502 NC_010468.1 3822169 3822792 D PFAM: protein of unknown function UPF0126; KEGG: sbo:SBO_0146 hypothetical protein; hypothetical protein 3822169..3822792 Escherichia coli ATCC 8739 6068515 YP_001726444.1 CDS EcolC_3503 NC_010468.1 3822839 3823183 R essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA complement(3822839..3823183) Escherichia coli ATCC 8739 6068539 YP_001726445.1 CDS EcolC_3504 NC_010468.1 3823265 3824686 R Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein complement(3823265..3824686) Escherichia coli ATCC 8739 6068554 YP_001726446.1 CDS EcolC_3505 NC_010468.1 3824911 3826191 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 3824911..3826191 Escherichia coli ATCC 8739 6068557 YP_001726447.1 CDS EcolC_3506 NC_010468.1 3826349 3828331 R part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease complement(3826349..3828331) Escherichia coli ATCC 8739 6068583 YP_001726448.1 CDS EcolC_3507 NC_010468.1 3828328 3829218 R Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit complement(3828328..3829218) Escherichia coli ATCC 8739 6068591 YP_001726449.1 CDS EcolC_3508 NC_010468.1 3829218 3830015 R part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit complement(3829218..3830015) Escherichia coli ATCC 8739 6068593 YP_001726450.1 CDS EcolC_3509 NC_010468.1 3830066 3832309 R involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter complement(3830066..3832309) Escherichia coli ATCC 8739 6068606 YP_001726451.1 CDS mrcB NC_010468.1 3832529 3835063 R bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b complement(3832529..3835063) Escherichia coli ATCC 8739 6068634 YP_001726452.1 CDS EcolC_3511 NC_010468.1 3835259 3837733 R similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB complement(3835259..3837733) Escherichia coli ATCC 8739 6068639 YP_001726453.1 CDS EcolC_3512 NC_010468.1 3837762 3838292 D TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: ssn:SSON_0159 hypothetical protein; 2'-5' RNA ligase 3837762..3838292 Escherichia coli ATCC 8739 6068642 YP_001726454.1 CDS EcolC_3513 NC_010468.1 3838307 3839011 D Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 3838307..3839011 Escherichia coli ATCC 8739 6068652 YP_001726455.1 CDS dksA NC_010468.1 3839189 3839644 D TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: sdy:SDY_0161 DnaK suppressor protein; RNA polymerase-binding transcription factor 3839189..3839644 Escherichia coli ATCC 8739 6068706 YP_001726456.1 CDS EcolC_3515 NC_010468.1 3839681 3840607 D this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 3839681..3840607 Escherichia coli ATCC 8739 6068710 YP_001726457.1 CDS pcnB NC_010468.1 3840667 3842064 D Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 3840667..3842064 Escherichia coli ATCC 8739 6068735 YP_001726458.1 CDS EcolC_3517 NC_010468.1 3842061 3842540 D catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 3842061..3842540 Escherichia coli ATCC 8739 6068738 YP_001726459.1 CDS EcolC_3518 NC_010468.1 3842889 3843482 D PFAM: Fimbrial protein; KEGG: stt:t0190 putative fimbrial protein; fimbrial protein 3842889..3843482 Escherichia coli ATCC 8739 6068741 YP_001726460.1 CDS EcolC_3519 NC_010468.1 3843565 3844290 D PFAM: pili assembly chaperone; KEGG: sbo:SBO_0126 probable pilin chaperone; putative chaperone protein EcpD 3843565..3844290 Escherichia coli ATCC 8739 6068743 YP_001726461.1 CDS EcolC_3520 NC_010468.1 3844331 3846931 D similar to the fimbrial usher protein PapC; putative outer membrane usher protein 3844331..3846931 Escherichia coli ATCC 8739 6068747 YP_001726462.1 CDS EcolC_3521 NC_010468.1 3846933 3847502 D KEGG: stt:t0187 putative fimbrial protein; putative fimbrial protein 3846933..3847502 Escherichia coli ATCC 8739 6064339 YP_001726463.1 CDS EcolC_3522 NC_010468.1 3847517 3848113 D PFAM: Fimbrial protein; KEGG: ssn:SSON_0146 putative fimbrial protein; fimbrial protein 3847517..3848113 Escherichia coli ATCC 8739 6067422 YP_001726464.1 CDS EcolC_3523 NC_010468.1 3848134 3848724 D PFAM: Fimbrial protein; KEGG: ssn:SSON_0145 putative fimbrial protein; fimbrial protein 3848134..3848724 Escherichia coli ATCC 8739 6067508 YP_001726465.1 CDS EcolC_3524 NC_010468.1 3848736 3849848 D PFAM: Fimbrial protein; KEGG: cko:CKO_03237 hypothetical protein; fimbrial protein 3848736..3849848 Escherichia coli ATCC 8739 6067222 YP_001726466.1 CDS panB NC_010468.1 3849982 3850776 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3849982..3850776 Escherichia coli ATCC 8739 6065475 YP_001726467.1 CDS panC NC_010468.1 3850788 3851639 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3850788..3851639 Escherichia coli ATCC 8739 6067499 YP_001726468.1 CDS EcolC_3527 NC_010468.1 3851713 3852615 R PFAM: putative transposase YhgA family protein; KEGG: sfv:SFV_0122 hypothetical protein; putative transposase YhgA family protein complement(3851713..3852615) Escherichia coli ATCC 8739 6065550 YP_001726469.1 CDS EcolC_3528 NC_010468.1 3852889 3853269 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 3852889..3853269 Escherichia coli ATCC 8739 6066021 YP_001726470.1 CDS EcolC_3529 NC_010468.1 3853273 3854502 R PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_0138 hypothetical protein; polysaccharide deacetylase complement(3853273..3854502) Escherichia coli ATCC 8739 6065048 YP_001726471.1 CDS EcolC_3530 NC_010468.1 3854566 3855006 R PFAM: PTS system fructose subfamily IIA component; KEGG: sbo:SBO_0118 putative PTS enzyme II B component; PTS system fructose subfamily transporter subunit IIA complement(3854566..3855006) Escherichia coli ATCC 8739 6067584 YP_001726472.1 CDS EcolC_3531 NC_010468.1 3855111 3855881 R PFAM: ABC-2 type transporter; KEGG: sdy:SDY_0037 hypothetical protein; ABC-2 type transporter complement(3855111..3855881) Escherichia coli ATCC 8739 6065005 YP_001726473.1 CDS EcolC_3532 NC_010468.1 3855878 3856804 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_0135 putative ATP-binding component of a transport system; ABC transporter-like protein complement(3855878..3856804) Escherichia coli ATCC 8739 6067327 YP_001726474.1 CDS EcolC_3533 NC_010468.1 3856913 3857575 D catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 3856913..3857575 Escherichia coli ATCC 8739 6067504 YP_001726475.1 CDS EcolC_3534 NC_010468.1 3857616 3858164 R KEGG: sdy:SDY_0034 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase complement(3857616..3858164) Escherichia coli ATCC 8739 6066064 YP_001726476.1 CDS EcolC_3535 NC_010468.1 3858358 3860748 D KEGG: sbo:SBO_0113 glucose dehydrogenase; TIGRFAM: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; PFAM: Pyrrolo-quinoline quinone; PQQ-dependent dehydrogenase glucose/quinate/shikimate family protein 3858358..3860748 Escherichia coli ATCC 8739 6065467 YP_001726477.1 CDS EcolC_3536 NC_010468.1 3860950 3862500 R laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase complement(3860950..3862500) Escherichia coli ATCC 8739 6065411 YP_001726478.1 CDS EcolC_3537 NC_010468.1 3862666 3863013 D KEGG: sdy:SDY_0029 hypothetical protein; hypothetical protein 3862666..3863013 Escherichia coli ATCC 8739 6065312 YP_001726479.1 CDS EcolC_3538 NC_010468.1 3863119 3863985 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3863119..3863985 Escherichia coli ATCC 8739 6064674 YP_001726480.1 CDS EcolC_3539 NC_010468.1 3864001 3864795 D S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 3864001..3864795 Escherichia coli ATCC 8739 6066037 YP_001726481.1 CDS EcolC_3540 NC_010468.1 3864832 3865194 R PFAM: conserved hypothetical protein; KEGG: sdy:SDY_0026 hypothetical protein; hypothetical protein complement(3864832..3865194) Escherichia coli ATCC 8739 6064880 YP_001726482.1 CDS EcolC_3541 NC_010468.1 3865369 3867966 R catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(3865369..3867966) Escherichia coli ATCC 8739 6065849 YP_001726483.1 CDS EcolC_3542 NC_010468.1 3868321 3870174 D KEGG: sfv:SFV_0108 hypothetical protein; hypothetical protein 3868321..3870174 Escherichia coli ATCC 8739 6064839 YP_001726484.1 CDS EcolC_3543 NC_010468.1 3870245 3871669 R E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(3870245..3871669) Escherichia coli ATCC 8739 6067616 YP_001726485.1 CDS aceF NC_010468.1 3871994 3873886 R E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase complement(3871994..3873886) Escherichia coli ATCC 8739 6064978 YP_001726486.1 CDS aceE NC_010468.1 3873901 3876564 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(3873901..3876564) Escherichia coli ATCC 8739 6067283 YP_001726487.1 CDS pdhR NC_010468.1 3876725 3877489 R activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR complement(3876725..3877489) Escherichia coli ATCC 8739 6065862 YP_001726488.1 CDS EcolC_3547 NC_010468.1 3878033 3879403 D PFAM: amino acid permease-associated region; KEGG: sfx:S0111 aromatic amino acid transport protein; aromatic amino acid transporter 3878033..3879403 Escherichia coli ATCC 8739 6064691 YP_001726489.1 CDS EcolC_3548 NC_010468.1 3879446 3880300 R involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE complement(3879446..3880300) Escherichia coli ATCC 8739 6067352 YP_001726490.1 CDS EcolC_3549 NC_010468.1 3880297 3880848 R PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sdy:SDY_0140 regulates AmpC; N-acetyl-anhydromuranmyl-L-alanine amidase complement(3880297..3880848) Escherichia coli ATCC 8739 6067302 YP_001726491.1 CDS EcolC_3550 NC_010468.1 3880936 3881829 D catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 3880936..3881829 Escherichia coli ATCC 8739 6066722 YP_001726492.1 CDS EcolC_3551 NC_010468.1 3882032 3882472 D KEGG: ssn:SSON_0116 prelipin peptidase dependent protein; putative major pilin subunit 3882032..3882472 Escherichia coli ATCC 8739 6067274 YP_001726493.1 CDS EcolC_3552 NC_010468.1 3882482 3883867 D PFAM: type II secretion system protein E; KEGG: sdy:SDY_0137 HofB; hypothetical protein 3882482..3883867 Escherichia coli ATCC 8739 6067403 YP_001726494.1 CDS EcolC_3553 NC_010468.1 3883857 3885059 D PFAM: type II secretion system protein; KEGG: ssn:SSON_0114 putative integral membrane protein; type IV pilin biogenesis protein 3883857..3885059 Escherichia coli ATCC 8739 6066593 YP_001726495.1 CDS EcolC_3554 NC_010468.1 3885094 3886137 R catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase complement(3885094..3886137) Escherichia coli ATCC 8739 6065967 YP_001726496.1 CDS coaE NC_010468.1 3886362 3886982 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3886362..3886982 Escherichia coli ATCC 8739 6068724 YP_001726497.1 CDS EcolC_3556 NC_010468.1 3886982 3887725 D PFAM: protein of unknown function DUF1342; KEGG: ssn:SSON_0110 hypothetical protein; hypothetical protein 3886982..3887725 Escherichia coli ATCC 8739 6065178 YP_001726498.1 CDS EcolC_3557 NC_010468.1 3887735 3887932 D PFAM: protein of unknown function DUF329; KEGG: sdy:SDY_0131 hypothetical protein; zinc-binding protein 3887735..3887932 Escherichia coli ATCC 8739 6064932 YP_001726499.1 CDS EcolC_3558 NC_010468.1 3888148 3888537 R TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: ssn:SSON_0107 7,8-dihydro-8-oxoguanine-triphosphatase; nucleoside triphosphate pyrophosphohydrolase complement(3888148..3888537) Escherichia coli ATCC 8739 6065146 YP_001726500.1 CDS EcolC_3559 NC_010468.1 3888597 3891302 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(3888597..3891302) Escherichia coli ATCC 8739 6064517 YP_001726501.1 CDS EcolC_3560 NC_010468.1 3891364 3891876 R secM translational pause allows for the initiation of secA translation; SecA regulator SecM complement(3891364..3891876) Escherichia coli ATCC 8739 6067518 YP_001726502.1 CDS lpxC NC_010468.1 3892107 3893024 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(3892107..3893024) Escherichia coli ATCC 8739 6064654 YP_001726503.1 CDS EcolC_3562 NC_010468.1 3893125 3894276 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(3893125..3894276) Escherichia coli ATCC 8739 6066132 YP_001726504.1 CDS ftsA NC_010468.1 3894337 3895599 R ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA complement(3894337..3895599) Escherichia coli ATCC 8739 6065608 YP_001726505.1 CDS EcolC_3564 NC_010468.1 3895596 3896426 R involved in septum formation; cell division protein FtsQ complement(3895596..3896426) Escherichia coli ATCC 8739 6067557 YP_001726506.1 CDS ddl NC_010468.1 3896428 3897348 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase complement(3896428..3897348) Escherichia coli ATCC 8739 6064984 YP_001726507.1 CDS murC NC_010468.1 3897341 3898816 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(3897341..3898816) Escherichia coli ATCC 8739 6064638 YP_001726508.1 CDS murG NC_010468.1 3898870 3899937 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase complement(3898870..3899937) Escherichia coli ATCC 8739 6065888 YP_001726509.1 CDS EcolC_3568 NC_010468.1 3899934 3901178 R integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW complement(3899934..3901178) Escherichia coli ATCC 8739 6065784 YP_001726510.1 CDS murD NC_010468.1 3901178 3902494 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(3901178..3902494) Escherichia coli ATCC 8739 6067407 YP_001726511.1 CDS mraY NC_010468.1 3902497 3903579 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(3902497..3903579) Escherichia coli ATCC 8739 6065737 YP_001726512.1 CDS murF NC_010468.1 3903573 3904931 R TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_0074 D-alanine:D-alanine-adding enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase complement(3903573..3904931) Escherichia coli ATCC 8739 6065724 YP_001726513.1 CDS murE NC_010468.1 3904928 3906415 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(3904928..3906415) Escherichia coli ATCC 8739 6064791 YP_001726514.1 CDS EcolC_3573 NC_010468.1 3906402 3908168 R PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: sdy:SDY_0114 penicillin-binding protein 3; peptidoglycan glycosyltransferase complement(3906402..3908168) Escherichia coli ATCC 8739 6066022 YP_001726515.1 CDS EcolC_3574 NC_010468.1 3908184 3908549 R membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL complement(3908184..3908549) Escherichia coli ATCC 8739 6066094 YP_001726516.1 CDS mraW NC_010468.1 3908546 3909487 R TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: sbo:SBO_0070 putative apolipoprotein; S-adenosyl-methyltransferase MraW complement(3908546..3909487) Escherichia coli ATCC 8739 6064428 YP_001726517.1 CDS EcolC_3576 NC_010468.1 3909489 3909947 R MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ complement(3909489..3909947) Escherichia coli ATCC 8739 6064414 YP_001726518.1 CDS EcolC_3577 NC_010468.1 3910549 3911553 R binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR complement(3910549..3911553) Escherichia coli ATCC 8739 6066561 YP_001726520.1 CDS ilvH NC_010468.1 3911733 3912224 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(3911733..3912224) Escherichia coli ATCC 8739 6064722 YP_001726521.1 CDS EcolC_3580 NC_010468.1 3912227 3913951 R catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit complement(3912227..3913951) Escherichia coli ATCC 8739 6067554 YP_001726522.1 CDS leuO NC_010468.1 3914269 3915213 R activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator complement(3914269..3915213) Escherichia coli ATCC 8739 6064870 YP_001726523.1 CDS EcolC_3582 NC_010468.1 3915873 3915959 D involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 3915873..3915959 Escherichia coli ATCC 8739 6067330 YP_001726524.1 CDS EcolC_3583 NC_010468.1 3916052 3917623 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 3916052..3917623 Escherichia coli ATCC 8739 6065434 YP_001726525.1 CDS EcolC_3584 NC_010468.1 3917623 3918714 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 3917623..3918714 Escherichia coli ATCC 8739 6064888 YP_001726526.1 CDS EcolC_3585 NC_010468.1 3918717 3920117 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 3918717..3920117 Escherichia coli ATCC 8739 6066420 YP_001726527.1 CDS leuD NC_010468.1 3920128 3920733 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 3920128..3920733 Escherichia coli ATCC 8739 6064448 YP_001726528.1 CDS EcolC_3587 NC_010468.1 3920782 3921960 R TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0067 putative transport protein; sugar efflux transporter complement(3920782..3921960) Escherichia coli ATCC 8739 6066270 YP_001726529.1 CDS EcolC_3588 NC_010468.1 3922282 3923937 D activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 3922282..3923937 Escherichia coli ATCC 8739 6064871 YP_001726530.1 CDS tbpA NC_010468.1 3924101 3925084 D part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 3924101..3925084 Escherichia coli ATCC 8739 6066442 YP_001726531.1 CDS thiP NC_010468.1 3925060 3926670 D permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 3925060..3926670 Escherichia coli ATCC 8739 6067549 YP_001726532.1 CDS thiQ NC_010468.1 3926654 3927352 D with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 3926654..3927352 Escherichia coli ATCC 8739 6067171 YP_001726533.1 CDS EcolC_3592 NC_010468.1 3927466 3928230 R PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_0052 hypothetical protein; hypothetical protein complement(3927466..3928230) Escherichia coli ATCC 8739 6065501 YP_001726534.1 CDS EcolC_3593 NC_010468.1 3928316 3929194 R positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC complement(3928316..3929194) Escherichia coli ATCC 8739 6065687 YP_001726535.1 CDS EcolC_3594 NC_010468.1 3929533 3931233 D catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 3929533..3931233 Escherichia coli ATCC 8739 6066889 YP_001726536.1 CDS EcolC_3595 NC_010468.1 3931244 3932746 D catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 3931244..3932746 Escherichia coli ATCC 8739 6067404 YP_001726537.1 CDS araD NC_010468.1 3933031 3933726 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3933031..3933726 Escherichia coli ATCC 8739 6066010 YP_001726538.1 CDS EcolC_3597 NC_010468.1 3933801 3936152 D Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 3933801..3936152 Escherichia coli ATCC 8739 6067600 YP_001726539.1 CDS EcolC_3598 NC_010468.1 3936317 3939223 D transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 3936317..3939223 Escherichia coli ATCC 8739 6065943 YP_001726540.1 CDS EcolC_3599 NC_010468.1 3939235 3939894 D catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 3939235..3939894 Escherichia coli ATCC 8739 6065577 YP_001726541.1 CDS djlA NC_010468.1 3940011 3940826 R functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein complement(3940011..3940826) Escherichia coli ATCC 8739 6065686 YP_001726542.1 CDS EcolC_3601 NC_010468.1 3941081 3943435 D determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 3941081..3943435 Escherichia coli ATCC 8739 6065189 YP_001726543.1 CDS EcolC_3602 NC_010468.1 3943488 3944774 D Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 3943488..3944774 Escherichia coli ATCC 8739 6066759 YP_001726544.1 CDS pdxA NC_010468.1 3944774 3945763 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 3944774..3945763 Escherichia coli ATCC 8739 6065044 YP_001726545.1 CDS ksgA NC_010468.1 3945760 3946581 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 3945760..3946581 Escherichia coli ATCC 8739 6066147 YP_001726546.1 CDS apaG NC_010468.1 3946584 3946961 D protein associated with Co2+ and Mg2+ efflux; ApaG protein 3946584..3946961 Escherichia coli ATCC 8739 6067532 YP_001726547.1 CDS apaH NC_010468.1 3946968 3947810 D hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 3946968..3947810 Escherichia coli ATCC 8739 6064730 YP_001726548.1 CDS folA NC_010468.1 3947888 3948367 R catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase complement(3947888..3948367) Escherichia coli ATCC 8739 6065447 YP_001726549.1 CDS EcolC_3608 NC_010468.1 3948559 3950421 R transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC complement(3948559..3950421) Escherichia coli ATCC 8739 6064728 YP_001726550.1 CDS EcolC_3609 NC_010468.1 3950414 3950944 R Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF complement(3950414..3950944) Escherichia coli ATCC 8739 6067323 YP_001726551.1 CDS EcolC_3610 NC_010468.1 3951052 3952383 R PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: sfv:SFV_0039 putative transport protein; major facilitator transporter complement(3951052..3952383) Escherichia coli ATCC 8739 6067519 YP_001726552.1 CDS EcolC_3611 NC_010468.1 3952440 3952727 R KEGG: sdy:SDY_0066 putative ferredoxin; putative ferredoxin complement(3952440..3952727) Escherichia coli ATCC 8739 6065011 YP_001726553.1 CDS EcolC_3612 NC_010468.1 3952724 3954010 R FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC complement(3952724..3954010) Escherichia coli ATCC 8739 6066013 YP_001726554.1 CDS fixB NC_010468.1 3954061 3955002 R involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB complement(3954061..3955002) Escherichia coli ATCC 8739 6066762 YP_001726555.1 CDS EcolC_3614 NC_010468.1 3955017 3955787 R required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA complement(3955017..3955787) Escherichia coli ATCC 8739 6065066 YP_001726556.1 CDS EcolC_3615 NC_010468.1 3956260 3957774 D catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 3956260..3957774 Escherichia coli ATCC 8739 6065045 YP_001726557.1 CDS EcolC_3616 NC_010468.1 3957805 3958947 D catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 3957805..3958947 Escherichia coli ATCC 8739 6066209 YP_001726558.1 CDS EcolC_3617 NC_010468.1 3959076 3960293 D catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 3959076..3960293 Escherichia coli ATCC 8739 6065959 YP_001726559.1 CDS caiC NC_010468.1 3960402 3961919 D PFAM: AMP-dependent synthetase and ligase; KEGG: ssn:SSON_0043 probable crotonobetaine/carnitine-CoA ligase; putative crotonobetaine/carnitine-CoA ligase 3960402..3961919 Escherichia coli ATCC 8739 6066113 YP_001726560.1 CDS EcolC_3619 NC_010468.1 3962028 3962813 D catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 3962028..3962813 Escherichia coli ATCC 8739 6064475 YP_001726561.1 CDS EcolC_3620 NC_010468.1 3962819 3963409 D involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 3962819..3963409 Escherichia coli ATCC 8739 6066415 YP_001726562.1 CDS EcolC_3621 NC_010468.1 3963528 3963923 R regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF complement(3963528..3963923) Escherichia coli ATCC 8739 6065610 YP_001726563.1 CDS carB NC_010468.1 3964185 3967406 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(3964185..3967406) Escherichia coli ATCC 8739 6065897 YP_001726564.1 CDS EcolC_3623 NC_010468.1 3967424 3968572 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(3967424..3968572) Escherichia coli ATCC 8739 6066559 YP_001726565.1 CDS EcolC_3624 NC_010468.1 3969028 3969849 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(3969028..3969849) Escherichia coli ATCC 8739 6065860 YP_001726566.1 CDS ispH NC_010468.1 3970995 3971945 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(3970995..3971945) Escherichia coli ATCC 8739 6067531 YP_001726567.1 CDS EcolC_3627 NC_010468.1 3971947 3972396 R PFAM: peptidylprolyl isomerase FKBP-type; KEGG: sbo:SBO_0027 probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase; FKBP-type peptidylprolyl isomerase complement(3971947..3972396) Escherichia coli ATCC 8739 6066455 YP_001726568.1 CDS lspA NC_010468.1 3972521 3973015 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(3972521..3973015) Escherichia coli ATCC 8739 6065960 YP_001726569.1 CDS ileS NC_010468.1 3973015 3975831 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(3973015..3975831) Escherichia coli ATCC 8739 6066553 YP_001726570.1 CDS EcolC_3630 NC_010468.1 3975874 3976815 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(3975874..3976815) Escherichia coli ATCC 8739 6067138 YP_001726571.1 CDS rpsT NC_010468.1 3977144 3977407 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 3977144..3977407 Escherichia coli ATCC 8739 6065941 YP_001726572.1 CDS EcolC_3632 NC_010468.1 3977883 3978580 D PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein join(3977883..3978137,3978137..3978580) Escherichia coli ATCC 8739 6066453 YP_001726573.1 CDS EcolC_3635 NC_010468.1 3981677 3981925 D hypothetical protein 3981677..3981925 Escherichia coli ATCC 8739 6067165 YP_001726574.1 CDS EcolC_3636 NC_010468.1 3982020 3982643 D KEGG: ssn:SSON_0023 hypothetical protein; hypothetical protein 3982020..3982643 Escherichia coli ATCC 8739 6067492 YP_001726575.1 CDS nhaR NC_010468.1 3982681 3983586 R Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR complement(3982681..3983586) Escherichia coli ATCC 8739 6065391 YP_001726576.1 CDS nhaA NC_010468.1 3983646 3984812 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(3983646..3984812) Escherichia coli ATCC 8739 6066352 YP_001726577.1 CDS EcolC_3639 NC_010468.1 3985398 3985550 D PFAM: Hok/gef cell toxic protein; KEGG: sbo:SBO_0017 Gef; Hok/gef cell toxic protein 3985398..3985550 Escherichia coli ATCC 8739 6065040 YP_001726578.1 CDS EcolC_3640 NC_010468.1 3985628 3986740 D PFAM: transposase IS4 family protein; KEGG: ssn:SSON_P186 IS186 ORF1; transposase IS4 family protein 3985628..3986740 Escherichia coli ATCC 8739 6064669 YP_001726579.1 CDS EcolC_3641 NC_010468.1 3987003 3988133 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(3987003..3988133) Escherichia coli ATCC 8739 6065813 YP_001726580.1 CDS dnaK NC_010468.1 3988222 3990138 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(3988222..3990138) Escherichia coli ATCC 8739 6064767 YP_001726581.1 CDS EcolC_3643 NC_010468.1 3990515 3990919 D KEGG: ssn:SSON_0013 hypothetical protein; hypothetical protein 3990515..3990919 Escherichia coli ATCC 8739 6065787 YP_001726582.1 CDS EcolC_3644 NC_010468.1 3990945 3991658 D PFAM: protein of unknown function UPF0174; KEGG: ssn:SSON_0012 putative oxidoreductase; hypothetical protein 3990945..3991658 Escherichia coli ATCC 8739 6065219 YP_001726583.1 CDS EcolC_3645 NC_010468.1 3991807 3992373 D PFAM: GPR1/FUN34/yaaH family protein; KEGG: ssn:SSON_0011 hypothetical protein; hypothetical protein 3991807..3992373 Escherichia coli ATCC 8739 6065785 YP_001726584.1 CDS mogA NC_010468.1 3992408 3992995 R forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA complement(3992408..3992995) Escherichia coli ATCC 8739 6067032 YP_001726585.1 CDS EcolC_3647 NC_010468.1 3993110 3994063 R KEGG: sbo:SBO_0009 transaldolase B; TIGRFAM: transaldolase; PFAM: Transaldolase; transaldolase B complement(3993110..3994063) Escherichia coli ATCC 8739 6066215 YP_001726586.1 CDS EcolC_3648 NC_010468.1 3994342 3995772 D TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdy:SDY_0007 inner membrane transport protein; amino acid carrier protein 3994342..3995772 Escherichia coli ATCC 8739 6065647 YP_001726587.1 CDS EcolC_3649 NC_010468.1 3995842 3996618 D PFAM: protein of unknown function DUF328; KEGG: sdy:SDY_0006 hypothetical protein; hypothetical protein 3995842..3996618 Escherichia coli ATCC 8739 6065175 YP_001726588.1 CDS EcolC_3650 NC_010468.1 3996771 3997067 R KEGG: ssn:SSON_0005 hypothetical protein; hypothetical protein complement(3996771..3997067) Escherichia coli ATCC 8739 6066297 YP_001726589.1 CDS EcolC_3651 NC_010468.1 3997281 3998567 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(3997281..3998567) Escherichia coli ATCC 8739 6065834 YP_001726590.1 CDS EcolC_3652 NC_010468.1 3998568 3999500 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(3998568..3999500) Escherichia coli ATCC 8739 6066546 YP_001726591.1 CDS thrA NC_010468.1 3999502 4001964 R multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I complement(3999502..4001964) Escherichia coli ATCC 8739 6065835 YP_001726592.1 CDS EcolC_3654 NC_010468.1 4002324 4003010 R member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase complement(4002324..4003010) Escherichia coli ATCC 8739 6065833 YP_001726593.1 CDS EcolC_3655 NC_010468.1 4003646 4004362 D PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sdy:SDY_4662 negative response regulator of genes in aerobic pathways; two-component response regulator 4003646..4004362 Escherichia coli ATCC 8739 6065456 YP_001726594.1 CDS EcolC_3656 NC_010468.1 4004420 4005772 R PFAM: Inner membrane CreD family protein; KEGG: sfx:S4703 inner membrane protein CreD; hypothetical protein complement(4004420..4005772) Escherichia coli ATCC 8739 6065911 YP_001726595.1 CDS EcolC_3657 NC_010468.1 4005830 4007254 R part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC complement(4005830..4007254) Escherichia coli ATCC 8739 6066129 YP_001726596.1 CDS EcolC_3658 NC_010468.1 4007254 4007943 R response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB complement(4007254..4007943) Escherichia coli ATCC 8739 6065801 YP_001726597.1 CDS EcolC_3659 NC_010468.1 4007956 4008429 R PFAM: CreA family protein; KEGG: sdy:SDY_4658 hypothetical protein; hypothetical protein complement(4007956..4008429) Escherichia coli ATCC 8739 6065143 YP_001726598.1 CDS EcolC_3660 NC_010468.1 4008640 4009509 D PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: sbo:SBO_4459 right origin-binding protein; AraC family transcriptional regulator 4008640..4009509 Escherichia coli ATCC 8739 6065311 YP_001726599.1 CDS EcolC_3661 NC_010468.1 4009506 4010153 R catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase complement(4009506..4010153) Escherichia coli ATCC 8739 6064808 YP_001726600.1 CDS EcolC_3662 NC_010468.1 4010205 4010726 D pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4010205..4010726 Escherichia coli ATCC 8739 6066705 YP_001726601.1 CDS EcolC_3663 NC_010468.1 4010811 4011137 R When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor complement(4010811..4011137) Escherichia coli ATCC 8739 6066703 YP_001726602.1 CDS EcolC_3664 NC_010468.1 4011227 4013164 R catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase complement(4011227..4013164) Escherichia coli ATCC 8739 6067270 YP_001726603.1 CDS EcolC_3665 NC_010468.1 4013375 4015042 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 4013375..4015042 Escherichia coli ATCC 8739 6065370 YP_001726604.1 CDS EcolC_3666 NC_010468.1 4015349 4016581 R catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase complement(4015349..4016581) Escherichia coli ATCC 8739 6065436 YP_001726605.1 CDS EcolC_3667 NC_010468.1 4016602 4017984 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(4016602..4017984) Escherichia coli ATCC 8739 6066137 YP_001726606.1 CDS serB NC_010468.1 4018033 4019001 R catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase complement(4018033..4019001) Escherichia coli ATCC 8739 6067415 YP_001726607.1 CDS EcolC_3669 NC_010468.1 4019107 4019751 D KEGG: sbo:SBO_4450 hypothetical protein; hypothetical protein 4019107..4019751 Escherichia coli ATCC 8739 6065271 YP_001726608.1 CDS lplA NC_010468.1 4019779 4020795 D Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4019779..4020795 Escherichia coli ATCC 8739 6065956 YP_001726609.1 CDS EcolC_3671 NC_010468.1 4020827 4021090 D PFAM: helix-turn-helix domain protein; KEGG: sfv:SFV_4419 hypothetical protein; helix-turn-helix domain-containing protein 4020827..4021090 Escherichia coli ATCC 8739 6066581 YP_001726610.1 CDS deoD NC_010468.1 4021250 4021969 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(4021250..4021969) Escherichia coli ATCC 8739 6065926 YP_001726611.1 CDS EcolC_3673 NC_010468.1 4022049 4023272 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(4022049..4023272) Escherichia coli ATCC 8739 6066784 YP_001726612.1 CDS deoA NC_010468.1 4023324 4024646 R Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase complement(4023324..4024646) Escherichia coli ATCC 8739 6066547 YP_001726613.1 CDS EcolC_3675 NC_010468.1 4024773 4025552 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(4024773..4025552) Escherichia coli ATCC 8739 6066195 YP_001726614.1 CDS EcolC_3676 NC_010468.1 4025810 4027360 D KEGG: ssn:SSON_4531 hypothetical protein; hypothetical protein 4025810..4027360 Escherichia coli ATCC 8739 6065963 YP_001726615.1 CDS EcolC_3677 NC_010468.1 4027332 4028195 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: sfv:SFV_4413 putative activating enzyme; radical SAM domain-containing protein 4027332..4028195 Escherichia coli ATCC 8739 6065870 YP_001726616.1 CDS EcolC_3678 NC_010468.1 4028712 4029494 R PFAM: TatD-related deoxyribonuclease; KEGG: ssn:SSON_4529 Mg-dependent DNase; putative deoxyribonuclease YjjV complement(4028712..4029494) Escherichia coli ATCC 8739 6065675 YP_001726617.1 CDS EcolC_3679 NC_010468.1 4029491 4030564 R PFAM: Patatin; KEGG: ssn:SSON_4528 hypothetical protein; patatin complement(4029491..4030564) Escherichia coli ATCC 8739 6066257 YP_001726618.1 CDS EcolC_3680 NC_010468.1 4030686 4030847 R PFAM: protein of unknown function DUF1328; KEGG: ssn:SSON_4527 hypothetical protein; hypothetical protein complement(4030686..4030847) Escherichia coli ATCC 8739 6065503 YP_001726619.1 CDS EcolC_3681 NC_010468.1 4030974 4031579 R PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ssn:SSON_4526 hyperosmotically inducible periplasmic protein; hypothetical protein complement(4030974..4031579) Escherichia coli ATCC 8739 6064655 YP_001726620.1 CDS prfC NC_010468.1 4031972 4033561 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(4031972..4033561) Escherichia coli ATCC 8739 6067181 YP_001726621.1 CDS EcolC_3683 NC_010468.1 4033652 4034329 R manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase complement(4033652..4034329) Escherichia coli ATCC 8739 6066735 YP_001726622.1 CDS rimI NC_010468.1 4034344 4034790 R alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase complement(4034344..4034790) Escherichia coli ATCC 8739 6065857 YP_001726623.1 CDS EcolC_3685 NC_010468.1 4034759 4035172 R with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi complement(4034759..4035172) Escherichia coli ATCC 8739 6066294 YP_001726624.1 CDS rsmC NC_010468.1 4035275 4036306 D 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4035275..4036306 Escherichia coli ATCC 8739 6067053 YP_001726625.1 CDS EcolC_3687 NC_010468.1 4036976 4037212 R PFAM: protein of unknown function DUF1435; KEGG: sbo:SBO_4428 putative inner membrane protein; hypothetical protein complement(4036976..4037212) Escherichia coli ATCC 8739 6065530 YP_001726626.1 CDS EcolC_3688 NC_010468.1 4037353 4038141 D PFAM: ferric iron reductase; KEGG: sbo:SBO_4427 hypothetical protein; ferric hydroximate transport ferric iron reductase 4037353..4038141 Escherichia coli ATCC 8739 6065962 YP_001726627.1 CDS EcolC_3689 NC_010468.1 4038179 4038802 R regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ complement(4038179..4038802) Escherichia coli ATCC 8739 6067507 YP_001726628.1 CDS EcolC_3690 NC_010468.1 4038814 4039539 R PFAM: regulatory protein LuxR; KEGG: sbo:SBO_4425 putative regulator; LuxR family transcriptional regulator complement(4038814..4039539) Escherichia coli ATCC 8739 6064438 YP_001726629.1 CDS EcolC_3691 NC_010468.1 4040158 4040928 D PFAM: protein of unknown function DUF1212; KEGG: sfv:SFV_4395 putative structural protein; hypothetical protein 4040158..4040928 Escherichia coli ATCC 8739 6066279 YP_001726630.1 CDS EcolC_3692 NC_010468.1 4040919 4041392 D KEGG: sfv:SFV_4394 hypothetical protein; hypothetical protein 4040919..4041392 Escherichia coli ATCC 8739 6067609 YP_001726631.1 CDS EcolC_3693 NC_010468.1 4041500 4042039 D This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4041500..4042039 Escherichia coli ATCC 8739 6067685 YP_001726632.1 CDS EcolC_3694 NC_010468.1 4042042 4042779 D acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4042042..4042779 Escherichia coli ATCC 8739 6067610 YP_001726633.1 CDS EcolC_3695 NC_010468.1 4042825 4043322 D KEGG: ssn:SSON_4506 putative glycoprotein/receptor; hypothetical protein 4042825..4043322 Escherichia coli ATCC 8739 6065616 YP_001726634.1 CDS EcolC_3696 NC_010468.1 4043576 4045867 D catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4043576..4045867 Escherichia coli ATCC 8739 6066737 YP_001726635.1 CDS EcolC_3697 NC_010468.1 4046007 4047029 R PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_4504 putative oxidoreductase; alcohol dehydrogenase complement(4046007..4047029) Escherichia coli ATCC 8739 6065936 YP_001726636.1 CDS EcolC_3698 NC_010468.1 4047168 4048082 D PFAM: GntR domain protein; KEGG: eca:ECA4381 putative DNA-binding protein; GntR family transcriptional regulator 4047168..4048082 Escherichia coli ATCC 8739 6065151 YP_001726637.1 CDS EcolC_3699 NC_010468.1 4048299 4049660 D PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_4387 putative transport protein; major facilitator transporter 4048299..4049660 Escherichia coli ATCC 8739 6068690 YP_001726638.1 CDS EcolC_3700 NC_010468.1 4049709 4051373 R PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sfv:SFV_4386 methyl-accepting chemotaxis protein I; methyl-accepting chemotaxis sensory transducer complement(4049709..4051373) Escherichia coli ATCC 8739 6067269 YP_001726639.1 CDS EcolC_3701 NC_010468.1 4051492 4051938 R TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein MarR; KEGG: sfv:SFV_4385 homoprotocatechuate degradative operon repressor; MarR family transcriptional regulator complement(4051492..4051938) Escherichia coli ATCC 8739 6064763 YP_001726640.1 CDS EcolC_3702 NC_010468.1 4052210 4053499 D KEGG: sbo:SBO_4412 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomerase; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase subunit HpaG1 4052210..4053499 Escherichia coli ATCC 8739 6066149 YP_001726641.1 CDS EcolC_3703 NC_010468.1 4053496 4054962 D TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: sbo:SBO_4411 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 4053496..4054962 Escherichia coli ATCC 8739 6065126 YP_001726642.1 CDS EcolC_3704 NC_010468.1 4054964 4055815 D KEGG: sbo:SBO_4410 homoprotocatechuate dyoxygenase; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; 3,4-dihydroxyphenylacetate 2,3-dioxygenase 4054964..4055815 Escherichia coli ATCC 8739 6065740 YP_001726643.1 CDS EcolC_3705 NC_010468.1 4055825 4056205 D PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: sfx:S4651 5-carboxymethyl-2-hydroxymuconate delta-isomerase; 5-carboxymethyl-2-hydroxymuconate isomerase 4055825..4056205 Escherichia coli ATCC 8739 6064640 YP_001726644.1 CDS EcolC_3706 NC_010468.1 4056273 4057076 D KEGG: ssn:SSON_4495 2-oxo-hept-3-ene-1,7-dioate hydratase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 4056273..4057076 Escherichia coli ATCC 8739 6065597 YP_001726645.1 CDS EcolC_3707 NC_010468.1 4057087 4057875 D KEGG: sbo:SBO_4407 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 4057087..4057875 Escherichia coli ATCC 8739 6065863 YP_001726646.1 CDS EcolC_3708 NC_010468.1 4058050 4059426 D TIGRFAM: 4-hydroxyphenylacetate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4406 putative 4-hydroxyphenylacetate permease; 4-hydroxyphenylacetate transporter 4058050..4059426 Escherichia coli ATCC 8739 6064898 YP_001726647.1 CDS EcolC_3709 NC_010468.1 4059436 4060326 D TIGRFAM: 4-hydroxyphenylacetate catabolism regulatory protein HpaA; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; KEGG: kpn:KPN_04781 4-hydroxyphenylacetate catabolism; AraC family transcriptional regulator 4059436..4060326 Escherichia coli ATCC 8739 6064706 YP_001726648.1 CDS EcolC_3710 NC_010468.1 4060577 4062139 D TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: ssn:SSON_4489 4-hydroxyphenylacetate 3-monooxygenase; 4-hydroxyphenylacetate 3-monooxygenase oxygenase subunit 4060577..4062139 Escherichia coli ATCC 8739 6064673 YP_001726649.1 CDS EcolC_3711 NC_010468.1 4062157 4062669 D TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit; PFAM: flavin reductase domain protein FMN-binding; KEGG: sbo:SBO_4403 4-hydroxyphenylacetate 3-monooxygenase coupling protein; 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit 4062157..4062669 Escherichia coli ATCC 8739 6064670 YP_001726650.1 CDS EcolC_3712 NC_010468.1 4063062 4065212 D PFAM: carbon starvation protein CstA; KEGG: sdy:SDY_4607 putative carbon starvation protein; carbon starvation protein CstA 4063062..4065212 Escherichia coli ATCC 8739 6067176 YP_001726651.1 CDS EcolC_3713 NC_010468.1 4065343 4065546 D PFAM: protein of unknown function DUF466; KEGG: sdy:SDY_4606 hypothetical protein; hypothetical protein 4065343..4065546 Escherichia coli ATCC 8739 6067182 YP_001726652.1 CDS EcolC_3714 NC_010468.1 4065557 4066513 D PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sfv:SFV_4371 hypothetical protein; putative GTP-binding protein YjiA 4065557..4066513 Escherichia coli ATCC 8739 6067166 YP_001726653.1 CDS EcolC_3715 NC_010468.1 4066582 4068234 R PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: gka:GK3294 hypothetical protein; hypothetical protein complement(4066582..4068234) Escherichia coli ATCC 8739 6066758 YP_001726654.1 CDS EcolC_3716 NC_010468.1 4068457 4069323 R PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit complement(4068457..4069323) Escherichia coli ATCC 8739 6066440 YP_001726655.1 CDS EcolC_3717 NC_010468.1 4069320 4069619 R PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein complement(4069320..4069619) Escherichia coli ATCC 8739 6068654 YP_001726656.1 CDS EcolC_3719 NC_010468.1 4070347 4072104 D PFAM: restriction modification system DNA specificity domain; KEGG: sfx:S4635 hypothetical protein; restriction modification system DNA specificity subunit 4070347..4072104 Escherichia coli ATCC 8739 6068714 YP_001726657.1 CDS EcolC_3720 NC_010468.1 4072325 4072666 D involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 4072325..4072666 Escherichia coli ATCC 8739 6068718 YP_001726658.1 CDS EcolC_3721 NC_010468.1 4072713 4074806 R PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF; KEGG: pcr:Pcryo_1606 protein of unknown function DUF1524 RloF; hypothetical protein complement(4072713..4074806) Escherichia coli ATCC 8739 6065928 YP_001726659.1 CDS EcolC_3722 NC_010468.1 4074903 4075067 R PFAM: protein of unknown function DUF1127; KEGG: sdy:SDY_4602 hypothetical protein; hypothetical protein complement(4074903..4075067) Escherichia coli ATCC 8739 6068559 YP_001726660.1 CDS EcolC_3723 NC_010468.1 4075244 4076656 D PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sdy:SDY_4601 putative regulator; transcriptional regulator 4075244..4076656 Escherichia coli ATCC 8739 6068694 YP_001726661.1 CDS EcolC_3724 NC_010468.1 4076898 4077842 R PFAM: putative transposase YhgA family protein; KEGG: sdy:SDY_4600 hypothetical protein; putative transposase YhgA family protein complement(4076898..4077842) Escherichia coli ATCC 8739 6068647 YP_001726662.1 CDS EcolC_3725 NC_010468.1 4078309 4079535 D PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4389 putative transport protein; major facilitator transporter 4078309..4079535 Escherichia coli ATCC 8739 6064413 YP_001726663.1 CDS EcolC_3726 NC_010468.1 4079568 4080860 D PFAM: protein of unknown function DUF445; KEGG: sbo:SBO_4388 hypothetical protein; hypothetical protein 4079568..4080860 Escherichia coli ATCC 8739 6066048 YP_001726664.1 CDS EcolC_3727 NC_010468.1 4080870 4081109 D KEGG: kpn:KPN_04766 hypothetical protein; hypothetical protein 4080870..4081109 Escherichia coli ATCC 8739 6064440 YP_001726665.1 CDS EcolC_3728 NC_010468.1 4081205 4082356 D PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: cko:CKO_03458 hypothetical protein; 2-hydroxyglutaryl-CoA dehydratase subunit D 4081205..4082356 Escherichia coli ATCC 8739 6065654 YP_001726666.1 CDS EcolC_3729 NC_010468.1 4082366 4083133 D TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: sdy:SDY_4596 putative enzyme; CoA-substrate-specific enzyme activase 4082366..4083133 Escherichia coli ATCC 8739 6064340 YP_001726667.1 CDS EcolC_3730 NC_010468.1 4083130 4083387 D KEGG: sbo:SBO_4385 hypothetical protein; hypothetical protein 4083130..4083387 Escherichia coli ATCC 8739 6064359 YP_001726668.1 CDS EcolC_3731 NC_010468.1 4083452 4084312 D PFAM: SdiA-regulated domain protein; KEGG: sbo:SBO_4384 hypothetical protein; SdiA-regulated domain-containing protein 4083452..4084312 Escherichia coli ATCC 8739 6064456 YP_001726669.1 CDS EcolC_3732 NC_010468.1 4084380 4085558 D PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: sbo:SBO_4383 putative transport protein; hypothetical protein 4084380..4085558 Escherichia coli ATCC 8739 6064590 YP_001726670.1 CDS EcolC_3734 NC_010468.1 4086374 4087057 D PFAM: nucleoside recognition domain protein; KEGG: sfx:S4444 hypothetical protein; nucleoside recognition domain-containing protein 4086374..4087057 Escherichia coli ATCC 8739 6064361 YP_001726671.1 CDS EcolC_3735 NC_010468.1 4087054 4087515 D PFAM: nucleoside recognition domain protein; KEGG: sbo:SBO_4380 hypothetical protein; hypothetical protein 4087054..4087515 Escherichia coli ATCC 8739 6064396 YP_001726672.1 CDS EcolC_3736 NC_010468.1 4087528 4088700 D KEGG: sbo:SBO_4379 isoaspartyl dipeptidase; TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; Amidohydrolase 3; isoaspartyl dipeptidase 4087528..4088700 Escherichia coli ATCC 8739 6064657 YP_001726673.1 CDS EcolC_3737 NC_010468.1 4088765 4089676 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_4199 putative transcriptional regulator LysR-type; putative DNA-binding transcriptional regulator 4088765..4089676 Escherichia coli ATCC 8739 6067725 YP_001726674.1 CDS iraD NC_010468.1 4089669 4090061 R inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein complement(4089669..4090061) Escherichia coli ATCC 8739 6068692 YP_001726675.1 CDS EcolC_3739 NC_010468.1 4090733 4091563 D KEGG: ssn:SSON_4480 hypothetical protein; hypothetical protein 4090733..4091563 Escherichia coli ATCC 8739 6068701 YP_001726676.1 CDS EcolC_3740 NC_010468.1 4091704 4092477 R regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR complement(4091704..4092477) Escherichia coli ATCC 8739 6068618 YP_001726677.1 CDS EcolC_3741 NC_010468.1 4092692 4093483 R PFAM: Mannitol dehydrogenase domain; KEGG: ssn:SSON_4478 D-mannonate oxidoreductase; mannitol dehydrogenase domain-containing protein complement(4092692..4093483) Escherichia coli ATCC 8739 6068459 YP_001726678.1 CDS EcolC_3742 NC_010468.1 4093533 4094702 R catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase complement(4093533..4094702) Escherichia coli ATCC 8739 6068116 YP_001726679.1 CDS EcolC_3743 NC_010468.1 4095489 4096391 R PFAM: Fimbrial protein ; FimH mannose-binding domain protein; KEGG: sfv:SFV_4206 FimH protein precursor; FimH mannose-binding domain-containing protein complement(4095489..4096391) Escherichia coli ATCC 8739 6067380 YP_001726680.1 CDS EcolC_3745 NC_010468.1 4096944 4097243 D PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_2924 IS3 ORF1; transposase IS3/IS911 family protein 4096944..4097243 Escherichia coli ATCC 8739 6068020 YP_001726681.1 CDS EcolC_3746 NC_010468.1 4097240 4098106 D PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2; integrase catalytic subunit 4097240..4098106 Escherichia coli ATCC 8739 6068630 YP_001726682.1 CDS EcolC_3748 NC_010468.1 4099512 4100531 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfv:SFV_4229 putative oxidoreductase; alcohol dehydrogenase 4099512..4100531 Escherichia coli ATCC 8739 6068040 YP_001726683.1 CDS EcolC_3749 NC_010468.1 4100661 4102163 D PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: ssn:SSON_4448 hypothetical protein; hypothetical protein 4100661..4102163 Escherichia coli ATCC 8739 6068088 YP_001726684.1 CDS EcolC_3750 NC_010468.1 4102282 4103364 R PFAM: permease YjgP/YjgQ family protein; KEGG: sdy:SDY_4286 hypothetical protein; YjgP/YjgQ family permease complement(4102282..4103364) Escherichia coli ATCC 8739 6068645 YP_001726685.1 CDS EcolC_3751 NC_010468.1 4103364 4104464 R PFAM: permease YjgP/YjgQ family protein; KEGG: sbo:SBO_4179 hypothetical protein; YjgP/YjgQ family permease complement(4103364..4104464) Escherichia coli ATCC 8739 6068629 YP_001726686.1 CDS EcolC_3752 NC_010468.1 4104731 4106242 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4104731..4106242 Escherichia coli ATCC 8739 6067778 YP_001726687.1 CDS EcolC_3753 NC_010468.1 4106596 4107039 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4106596..4107039 Escherichia coli ATCC 8739 6068670 YP_001726688.1 CDS valS NC_010468.1 4107039 4109894 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4107039..4109894 Escherichia coli ATCC 8739 6068110 YP_001726689.1 CDS EcolC_3755 NC_010468.1 4109950 4111146 R PFAM: protein of unknown function DUF898 transmembrane; KEGG: sfx:S4493 hypothetical protein; hypothetical protein complement(4109950..4111146) Escherichia coli ATCC 8739 6068637 YP_001726690.1 CDS EcolC_3756 NC_010468.1 4111339 4111842 D PFAM: GCN5-related N-acetyltransferase; KEGG: sfl:SF4233 putative acetyltransferase; N-acetyltransferase GCN5 4111339..4111842 Escherichia coli ATCC 8739 6067785 YP_001726691.1 CDS EcolC_3757 NC_010468.1 4111888 4112304 R PFAM: protein of unknown function DUF1260; KEGG: sdy:SDY_4277 hypothetical protein; hypothetical protein complement(4111888..4112304) Escherichia coli ATCC 8739 6067374 YP_001726692.1 CDS EcolC_3758 NC_010468.1 4112466 4113470 D catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 4112466..4113470 Escherichia coli ATCC 8739 6068674 YP_001726693.1 CDS EcolC_3761 NC_010468.1 4115254 4115706 R PFAM: conserved hypothetical protein; KEGG: sdy:SDY_4270 hypothetical protein; hypothetical protein complement(4115254..4115706) Escherichia coli ATCC 8739 6068136 YP_001726694.1 CDS EcolC_3762 NC_010468.1 4115851 4116444 R PFAM: regulatory protein TetR; KEGG: sfv:SFV_4244 hypothetical protein; TetR family transcriptional regulator complement(4115851..4116444) Escherichia coli ATCC 8739 6068128 YP_001726695.1 CDS EcolC_3763 NC_010468.1 4116515 4117228 D PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sfv:SFV_4245 putative oxidoreductase; oxidoreductase 4116515..4117228 Escherichia coli ATCC 8739 6067761 YP_001726696.1 CDS EcolC_3764 NC_010468.1 4117359 4117754 D PFAM: Endoribonuclease L-PSP; KEGG: ssn:SSON_4428 hypothetical protein; endoribonuclease L-PSP 4117359..4117754 Escherichia coli ATCC 8739 6068142 YP_001726697.1 CDS EcolC_3765 NC_010468.1 4118035 4118169 D PFAM: PyrBI operon leader peptide; KEGG: sdy:SDY_4265 pyrBI operon leader peptide; pyrBI operon leader peptide 4118035..4118169 Escherichia coli ATCC 8739 6068091 YP_001726698.1 CDS pyrB NC_010468.1 4118173 4119108 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4118173..4119108 Escherichia coli ATCC 8739 6064629 YP_001726699.1 CDS EcolC_3767 NC_010468.1 4119121 4119582 D involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4119121..4119582 Escherichia coli ATCC 8739 6064662 YP_001726700.1 CDS EcolC_3768 NC_010468.1 4119655 4120041 D TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sdy:SDY_4262 hypothetical protein; endoribonuclease L-PSP 4119655..4120041 Escherichia coli ATCC 8739 6064692 YP_001726701.1 CDS EcolC_3769 NC_010468.1 4120247 4122943 R P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA complement(4120247..4122943) Escherichia coli ATCC 8739 6065249 YP_001726702.1 CDS treR NC_010468.1 4123322 4124269 D regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4123322..4124269 Escherichia coli ATCC 8739 6065023 YP_001726703.1 CDS EcolC_3771 NC_010468.1 4124388 4125809 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4124388..4125809 Escherichia coli ATCC 8739 6065276 YP_001726704.1 CDS EcolC_3772 NC_010468.1 4125859 4127514 D KEGG: sfx:S4513 trehalase 6-P hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; trehalose-6-phosphate hydrolase 4125859..4127514 Escherichia coli ATCC 8739 6065637 YP_001726705.1 CDS EcolC_3773 NC_010468.1 4127908 4130046 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4127908..4130046 Escherichia coli ATCC 8739 6066425 YP_001726706.1 CDS nrdG NC_010468.1 4130206 4130670 D activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4130206..4130670 Escherichia coli ATCC 8739 6066452 YP_001726707.1 CDS EcolC_3775 NC_010468.1 4130715 4131101 R PFAM: cytochrome b562; KEGG: sfv:SFV_4255 cytochrome b(562); cytochrome b562 complement(4130715..4131101) Escherichia coli ATCC 8739 6066516 YP_001726708.1 CDS EcolC_3776 NC_010468.1 4131156 4132508 R protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA complement(4131156..4132508) Escherichia coli ATCC 8739 6066604 YP_001726709.1 CDS EcolC_3777 NC_010468.1 4132602 4133153 D PFAM: protein of unknown function DUF615; KEGG: ssn:SSON_4415 putative alpha helix protein; hypothetical protein 4132602..4133153 Escherichia coli ATCC 8739 6066625 YP_001726710.1 CDS EcolC_3778 NC_010468.1 4133309 4134682 R TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sbo:SBO_4213 putative ligase; UDP-N-acetylmuramate complement(4133309..4134682) Escherichia coli ATCC 8739 6066641 YP_001726711.1 CDS EcolC_3779 NC_010468.1 4134858 4135856 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4134858..4135856 Escherichia coli ATCC 8739 6066793 YP_001726712.1 CDS EcolC_3780 NC_010468.1 4135889 4136884 R membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease YjfF complement(4135889..4136884) Escherichia coli ATCC 8739 6066882 YP_001726713.1 CDS EcolC_3781 NC_010468.1 4136871 4137893 R PFAM: inner-membrane translocator; KEGG: ssn:SSON_4411 putative transport system permease protein; monosaccharide-transporting ATPase complement(4136871..4137893) Escherichia coli ATCC 8739 6067637 YP_001726714.1 CDS EcolC_3782 NC_010468.1 4137907 4139409 R PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ssn:SSON_4410 putative ATP-binding component of a transport system; ABC transporter-like protein complement(4137907..4139409) Escherichia coli ATCC 8739 6067580 YP_001726715.1 CDS EcolC_3783 NC_010468.1 4139549 4140505 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sbo:SBO_4218 putative LacI-type transcriptional regulator; periplasmic binding protein/LacI transcriptional regulator complement(4139549..4140505) Escherichia coli ATCC 8739 6066398 YP_001726716.1 CDS EcolC_3784 NC_010468.1 4140815 4141345 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4140815..4141345 Escherichia coli ATCC 8739 6067329 YP_001726717.1 CDS EcolC_3785 NC_010468.1 4141725 4142066 R PFAM: AIG2 family protein; KEGG: sdy:SDY_4459 hypothetical protein; AIG2 family protein complement(4141725..4142066) Escherichia coli ATCC 8739 6066117 YP_001726718.1 CDS EcolC_3786 NC_010468.1 4142069 4145848 R PFAM: protein of unknown function DUF490; KEGG: ssn:SSON_4406 hypothetical protein; hypothetical protein complement(4142069..4145848) Escherichia coli ATCC 8739 6065055 YP_001726719.1 CDS EcolC_3787 NC_010468.1 4145845 4147578 R PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: sbo:SBO_4223 hypothetical protein; surface antigen (D15) complement(4145845..4147578) Escherichia coli ATCC 8739 6066462 YP_001726720.1 CDS EcolC_3788 NC_010468.1 4147784 4148422 D this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4147784..4148422 Escherichia coli ATCC 8739 6065856 YP_001726721.1 CDS EcolC_3789 NC_010468.1 4148745 4150088 D PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sdy:SDY_4455 putative transport protein; hypothetical protein 4148745..4150088 Escherichia coli ATCC 8739 6067297 YP_001726722.1 CDS EcolC_3790 NC_010468.1 4150150 4150356 R PFAM: protein of unknown function DUF1107; KEGG: sdy:SDY_4454 hypothetical protein; hypothetical protein complement(4150150..4150356) Escherichia coli ATCC 8739 6067385 YP_001726723.1 CDS EcolC_3791 NC_010468.1 4150681 4151238 D PFAM: conserved hypothetical protein; KEGG: sbo:SBO_4227 hypothetical protein; hypothetical protein 4150681..4151238 Escherichia coli ATCC 8739 6067408 YP_001726724.1 CDS EcolC_3792 NC_010468.1 4151228 4151968 R catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase complement(4151228..4151968) Escherichia coli ATCC 8739 6067472 YP_001726725.1 CDS cpdB NC_010468.1 4152158 4154101 D periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4152158..4154101 Escherichia coli ATCC 8739 6067232 YP_001726726.1 CDS EcolC_3794 NC_010468.1 4154224 4154604 R PFAM: helix-turn-helix HxlR type; KEGG: sbo:SBO_4232 hypothetical protein; HxlR family transcriptional regulator complement(4154224..4154604) Escherichia coli ATCC 8739 6067289 YP_001726727.1 CDS EcolC_3795 NC_010468.1 4154693 4155553 D PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: sbo:SBO_4231 putative oxidoreductase; NmrA family protein 4154693..4155553 Escherichia coli ATCC 8739 6067296 YP_001726728.1 CDS EcolC_3796 NC_010468.1 4155662 4156627 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4395 putative transmembrane subunit; hypothetical protein 4155662..4156627 Escherichia coli ATCC 8739 6067652 YP_001726729.1 CDS EcolC_3797 NC_010468.1 4156735 4157397 D Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4156735..4157397 Escherichia coli ATCC 8739 6066191 YP_001726730.1 CDS EcolC_3798 NC_010468.1 4157442 4158854 R involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease complement(4157442..4158854) Escherichia coli ATCC 8739 6067262 YP_001726731.1 CDS EcolC_3799 NC_010468.1 4159163 4159783 R FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase complement(4159163..4159783) Escherichia coli ATCC 8739 6067626 YP_001726732.1 CDS EcolC_3800 NC_010468.1 4160002 4160640 D PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sdy:SDY_4376 hypothetical protein; opacity-associated protein A 4160002..4160640 Escherichia coli ATCC 8739 6066619 YP_001726733.1 CDS EcolC_3801 NC_010468.1 4160624 4161271 R PFAM: regulatory protein TetR; KEGG: sfv:SFV_4282 hypothetical protein; TetR family transcriptional regulator complement(4160624..4161271) Escherichia coli ATCC 8739 6066974 YP_001726734.1 CDS EcolC_3802 NC_010468.1 4161484 4162275 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4161484..4162275 Escherichia coli ATCC 8739 6067343 YP_001726735.1 CDS EcolC_3803 NC_010468.1 4162285 4163127 D PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sbo:SBO_4242 hypothetical protein; xylose isomerase domain-containing protein 4162285..4163127 Escherichia coli ATCC 8739 6067527 YP_001726736.1 CDS EcolC_3804 NC_010468.1 4163137 4163913 D PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sbo:SBO_4243 hypothetical protein; enoyl-CoA hydratase/isomerase 4163137..4163913 Escherichia coli ATCC 8739 6066753 YP_001726737.1 CDS EcolC_3806 NC_010468.1 4165460 4167541 D PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: rle:RL1831 putative oxidoreductase/dehydrogenase flavoprotein binding; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 4165460..4167541 Escherichia coli ATCC 8739 6064951 YP_001726738.1 CDS EcolC_3807 NC_010468.1 4167562 4168038 D PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: plu:plu0173 hypothetical protein; tripartite ATP-independent periplasmic transporter DctQ 4167562..4168038 Escherichia coli ATCC 8739 6064877 YP_001726739.1 CDS EcolC_3808 NC_010468.1 4168081 4169382 D TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ppr:PBPRB1879 C4-dicarboxylate transport system, putative integral membrane protein; TRAP dicarboxylate transporter subunit DctM 4168081..4169382 Escherichia coli ATCC 8739 6066845 YP_001726740.1 CDS EcolC_3809 NC_010468.1 4169435 4170406 D TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: ssn:SSON_4387 putative dicarboxylate-binding periplasmic protein; TRAP dicarboxylate transporter subunit DctP 4169435..4170406 Escherichia coli ATCC 8739 6067842 YP_001726741.1 CDS rplI NC_010468.1 4170520 4170969 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(4170520..4170969) Escherichia coli ATCC 8739 6067310 YP_001726742.1 CDS rpsR NC_010468.1 4171011 4171238 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(4171011..4171238) Escherichia coli ATCC 8739 6067537 YP_001726743.1 CDS EcolC_3812 NC_010468.1 4171243 4171557 R binds single-stranded DNA at the primosome assembly site; primosomal replication protein N complement(4171243..4171557) Escherichia coli ATCC 8739 6064493 YP_001726744.1 CDS rpsF NC_010468.1 4171564 4171959 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(4171564..4171959) Escherichia coli ATCC 8739 6067273 YP_001726745.1 CDS EcolC_3814 NC_010468.1 4172286 4172561 D PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_4255 hypothetical protein; hypothetical protein 4172286..4172561 Escherichia coli ATCC 8739 6064959 YP_001726746.1 CDS sgaE NC_010468.1 4172690 4173376 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(4172690..4173376) Escherichia coli ATCC 8739 6064755 YP_001726747.1 CDS EcolC_3816 NC_010468.1 4173376 4174230 R UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase complement(4173376..4174230) Escherichia coli ATCC 8739 6064642 YP_001726748.1 CDS ulaD NC_010468.1 4174240 4174890 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(4174240..4174890) Escherichia coli ATCC 8739 6064702 YP_001726749.1 CDS EcolC_3818 NC_010468.1 4174904 4175368 R involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA complement(4174904..4175368) Escherichia coli ATCC 8739 6064829 YP_001726750.1 CDS EcolC_3819 NC_010468.1 4175378 4175683 R involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB complement(4175378..4175683) Escherichia coli ATCC 8739 6064716 YP_001726751.1 CDS ulaA NC_010468.1 4175699 4177096 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(4175699..4177096) Escherichia coli ATCC 8739 6067199 YP_001726752.1 CDS EcolC_3821 NC_010468.1 4177451 4178515 D KEGG: ssn:SSON_4374 hypothetical protein; putative L-ascorbate 6-phosphate lactonase 4177451..4178515 Escherichia coli ATCC 8739 6065981 YP_001726753.1 CDS EcolC_3822 NC_010468.1 4178623 4179378 D negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4178623..4179378 Escherichia coli ATCC 8739 6065387 YP_001726754.1 CDS EcolC_3823 NC_010468.1 4179375 4180124 R YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase complement(4179375..4180124) Escherichia coli ATCC 8739 6065192 YP_001726755.1 CDS EcolC_3824 NC_010468.1 4180306 4180635 D in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A 4180306..4180635 Escherichia coli ATCC 8739 6064983 YP_001726756.1 CDS EcolC_3825 NC_010468.1 4180784 4181059 D PFAM: protein of unknown function DUF1471; KEGG: sbo:SBO_4267 hypothetical protein; hypothetical protein 4180784..4181059 Escherichia coli ATCC 8739 6065059 YP_001726757.1 CDS EcolC_3826 NC_010468.1 4181176 4182801 R catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase complement(4181176..4182801) Escherichia coli ATCC 8739 6065082 YP_001726758.1 CDS EcolC_3827 NC_010468.1 4182885 4184048 R PFAM: glutathionylspermidine synthase; KEGG: sfx:S4608 putative synthetase/amidase; glutathionylspermidine synthase complement(4182885..4184048) Escherichia coli ATCC 8739 6065187 YP_001726759.1 CDS EcolC_3828 NC_010468.1 4184051 4184689 R PFAM: protein of unknown function DUF1190; KEGG: sfv:SFV_4341 hypothetical protein; hypothetical protein complement(4184051..4184689) Escherichia coli ATCC 8739 6065392 YP_001726760.1 CDS EcolC_3829 NC_010468.1 4184699 4185097 R PFAM: protein of unknown function DUF350; KEGG: sbo:SBO_4271 hypothetical protein; hypothetical protein complement(4184699..4185097) Escherichia coli ATCC 8739 6065517 YP_001726761.1 CDS EcolC_3830 NC_010468.1 4185115 4185774 R KEGG: sbo:SBO_4272 hypothetical protein; hypothetical protein complement(4185115..4185774) Escherichia coli ATCC 8739 6065595 YP_001726762.1 CDS EcolC_3831 NC_010468.1 4185825 4186523 R PFAM: PspA/IM30 family protein; KEGG: sbo:SBO_4273 putative alpha helical protein; phage shock protein A, PspA complement(4185825..4186523) Escherichia coli ATCC 8739 6065766 YP_001726763.1 CDS EcolC_3832 NC_010468.1 4186542 4186943 R KEGG: stm:STM4370 putative cytoplasmic protein; putative cytoplasmic protein complement(4186542..4186943) Escherichia coli ATCC 8739 6065832 YP_001726764.1 CDS EcolC_3833 NC_010468.1 4187070 4187801 R Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(4187070..4187801) Escherichia coli ATCC 8739 6065899 YP_001726765.1 CDS EcolC_3834 NC_010468.1 4187981 4190422 R 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R complement(4187981..4190422) Escherichia coli ATCC 8739 6064737 YP_001726766.1 CDS EcolC_3835 NC_010468.1 4190461 4190886 R negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR complement(4190461..4190886) Escherichia coli ATCC 8739 6066284 YP_001726767.1 CDS EcolC_3836 NC_010468.1 4191091 4192389 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(4191091..4192389) Escherichia coli ATCC 8739 6066205 YP_001726768.1 CDS EcolC_3837 NC_010468.1 4192493 4192690 R KEGG: sdy:SDY_4413 hypothetical protein; hypothetical protein complement(4192493..4192690) Escherichia coli ATCC 8739 6066322 YP_001726769.1 CDS EcolC_3838 NC_010468.1 4192772 4193776 R with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC complement(4192772..4193776) Escherichia coli ATCC 8739 6066438 YP_001726770.1 CDS EcolC_3839 NC_010468.1 4193779 4195038 R with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK complement(4193779..4195038) Escherichia coli ATCC 8739 6066473 YP_001726771.1 CDS EcolC_3840 NC_010468.1 4195124 4196404 R involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX complement(4195124..4196404) Escherichia coli ATCC 8739 6064497 YP_001726772.1 CDS hfq NC_010468.1 4196480 4196788 R Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq complement(4196480..4196788) Escherichia coli ATCC 8739 6066185 YP_001726773.1 CDS miaA NC_010468.1 4196874 4197824 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(4196874..4197824) Escherichia coli ATCC 8739 6066860 YP_001726774.1 CDS mutL NC_010468.1 4197817 4199664 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(4197817..4199664) Escherichia coli ATCC 8739 6066878 YP_001726775.1 CDS EcolC_3844 NC_010468.1 4199674 4201011 R PFAM: cell wall hydrolase/autolysin; KEGG: ssn:SSON_4354 N-acetylmuramoyl-L-alanine amidase II; N-acetylmuramoyl-l-alanine amidase II complement(4199674..4201011) Escherichia coli ATCC 8739 6066881 YP_001726776.1 CDS EcolC_3845 NC_010468.1 4201030 4201491 R possibly involved in cell wall synthesis; putative ATPase complement(4201030..4201491) Escherichia coli ATCC 8739 6067081 YP_001726777.1 CDS EcolC_3846 NC_010468.1 4201463 4202995 R TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: sbo:SBO_4290 hypothetical protein; hypothetical protein complement(4201463..4202995) Escherichia coli ATCC 8739 6066898 YP_001726778.1 CDS EcolC_3847 NC_010468.1 4203009 4204148 D TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: sfv:SFV_4325 hypothetical protein; iron-sulfur cluster binding protein 4203009..4204148 Escherichia coli ATCC 8739 6064404 YP_001726779.1 CDS EcolC_3848 NC_010468.1 4204927 4205472 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(4204927..4205472) Escherichia coli ATCC 8739 6067331 YP_001726780.1 CDS EcolC_3849 NC_010468.1 4205567 4206619 D EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4205567..4206619 Escherichia coli ATCC 8739 6067388 YP_001726781.1 CDS psd NC_010468.1 4206716 4207684 D catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4206716..4207684 Escherichia coli ATCC 8739 6067211 YP_001726782.1 CDS EcolC_3851 NC_010468.1 4207706 4211029 D PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_4298 putative periplasmic binding protein; hypothetical protein 4207706..4211029 Escherichia coli ATCC 8739 6067446 YP_001726783.1 CDS EcolC_3852 NC_010468.1 4211058 4211372 R KEGG: stm:STM4346 putative inner membrane protein; putative inner membrane protein complement(4211058..4211372) Escherichia coli ATCC 8739 6064349 YP_001726784.1 CDS EcolC_3853 NC_010468.1 4211369 4211683 R KEGG: spt:SPA4163 hypothetical protein; hypothetical protein complement(4211369..4211683) Escherichia coli ATCC 8739 6064499 YP_001726785.1 CDS EcolC_3854 NC_010468.1 4211735 4213237 R PFAM: amino acid permease-associated region; KEGG: sdy:SDY_4434 putative transport; amino acid permease-associated protein complement(4211735..4213237) Escherichia coli ATCC 8739 6064454 YP_001726786.1 CDS EcolC_3855 NC_010468.1 4213456 4214433 R lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase complement(4213456..4214433) Escherichia coli ATCC 8739 6067544 YP_001726787.1 CDS EcolC_3856 NC_010468.1 4214758 4216566 D part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4214758..4216566 Escherichia coli ATCC 8739 6067558 YP_001726788.1 CDS EcolC_3857 NC_010468.1 4216559 4217293 D part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4216559..4217293 Escherichia coli ATCC 8739 6064382 YP_001726789.1 CDS EcolC_3858 NC_010468.1 4217304 4217699 D part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4217304..4217699 Escherichia coli ATCC 8739 6064445 YP_001726790.1 CDS EcolC_3859 NC_010468.1 4217710 4218069 D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4217710..4218069 Escherichia coli ATCC 8739 6064437 YP_001726791.1 CDS ampC NC_010468.1 4218132 4219265 D PFAM: beta-lactamase; KEGG: sbo:SBO_4306 beta-lactamase; beta-lactamase 4218132..4219265 Escherichia coli ATCC 8739 6067598 YP_001726792.1 CDS EcolC_3861 NC_010468.1 4219354 4219887 D lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4219354..4219887 Escherichia coli ATCC 8739 6067619 YP_001726793.1 CDS EcolC_3862 NC_010468.1 4219884 4220201 R member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE complement(4219884..4220201) Escherichia coli ATCC 8739 6067308 YP_001726794.1 CDS EcolC_3863 NC_010468.1 4220376 4220522 R PFAM: Entericidin EcnAB; KEGG: ssn:SSON_4333 putative toxin of osmotically regulated toxin-antitoxin system associated with programmed cell death; entericidin B membrane lipoprotein complement(4220376..4220522) Escherichia coli ATCC 8739 6067633 YP_001726795.1 CDS EcolC_3864 NC_010468.1 4220633 4220758 R acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A complement(4220633..4220758) Escherichia coli ATCC 8739 6068746 YP_001726796.1 CDS EcolC_3865 NC_010468.1 4220810 4221376 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(4220810..4221376) Escherichia coli ATCC 8739 6064580 YP_001726797.1 CDS EcolC_3866 NC_010468.1 4221418 4222446 D KEGG: sfx:S4569 hypothetical protein; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; lysine 2,3-aminomutase YodO family protein 4221418..4222446 Escherichia coli ATCC 8739 6066496 YP_001726798.1 CDS EcolC_3867 NC_010468.1 4222840 4223709 D KEGG: sbo:SBO_4311 hypothetical protein; hypothetical protein 4222840..4223709 Escherichia coli ATCC 8739 6065105 YP_001726799.1 CDS EcolC_3868 NC_010468.1 4223912 4224265 R KEGG: sdy:SDY_4450 hypothetical protein; hypothetical protein complement(4223912..4224265) Escherichia coli ATCC 8739 6064500 YP_001726800.1 CDS groEL NC_010468.1 4224403 4226049 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(4224403..4226049) Escherichia coli ATCC 8739 6065803 YP_001726801.1 CDS groES NC_010468.1 4226093 4226386 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(4226093..4226386) Escherichia coli ATCC 8739 6064840 YP_001726802.1 CDS EcolC_3871 NC_010468.1 4226662 4227918 D uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 4226662..4227918 Escherichia coli ATCC 8739 6064620 YP_001726803.1 CDS fxsA NC_010468.1 4227934 4228410 R F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein complement(4227934..4228410) Escherichia coli ATCC 8739 6067443 YP_001726804.1 CDS aspA NC_010468.1 4228747 4230183 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4228747..4230183 Escherichia coli ATCC 8739 6065160 YP_001726805.1 CDS EcolC_3874 NC_010468.1 4230301 4231602 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4230301..4231602 Escherichia coli ATCC 8739 6064614 YP_001726806.1 CDS EcolC_3875 NC_010468.1 4231718 4232056 D copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4231718..4232056 Escherichia coli ATCC 8739 6064498 YP_001726807.1 CDS dipZ NC_010468.1 4232032 4233729 D two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4232032..4233729 Escherichia coli ATCC 8739 6066324 YP_001726808.1 CDS EcolC_3877 NC_010468.1 4233766 4234341 D PFAM: regulatory protein TetR; KEGG: ssn:SSON_4318 hypothetical protein; putative transcriptional regulator 4233766..4234341 Escherichia coli ATCC 8739 6066392 YP_001726809.1 CDS EcolC_3878 NC_010468.1 4234721 4235986 D PFAM: integrase family protein; KEGG: sfx:S4822 putative P4-type integrase; integrase family protein 4234721..4235986 Escherichia coli ATCC 8739 6067834 YP_001726810.1 CDS EcolC_3881 NC_010468.1 4238126 4238823 R PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein complement(join(4238126..4238569,4238569..4238823)) Escherichia coli ATCC 8739 6064343 YP_001726811.1 CDS EcolC_3882 NC_010468.1 4239557 4241671 R PFAM: UvrD/REP helicase; KEGG: mgm:Mmc1_1352 UvrD/REP helicase; UvrD/REP helicase complement(4239557..4241671) Escherichia coli ATCC 8739 6064344 YP_001726812.1 CDS EcolC_3883 NC_010468.1 4241668 4248009 R PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: mgm:Mmc1_1353 DEAD/DEAH box helicase domain protein; helicase superfamily protein complement(4241668..4248009) Escherichia coli ATCC 8739 6064346 YP_001726813.1 CDS EcolC_3884 NC_010468.1 4248009 4252937 R KEGG: mgm:Mmc1_1354 hypothetical protein; hypothetical protein complement(4248009..4252937) Escherichia coli ATCC 8739 6064348 YP_001726814.1 CDS EcolC_3885 NC_010468.1 4252940 4255798 R PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; KEGG: mgm:Mmc1_1355 helicase domain protein; helicase domain-containing protein complement(4252940..4255798) Escherichia coli ATCC 8739 6064350 YP_001726815.1 CDS EcolC_3886 NC_010468.1 4256022 4262336 R PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: lpf:lpl2494 hypothetical protein; helicase superfamily protein complement(4256022..4262336) Escherichia coli ATCC 8739 6064351 YP_001726816.1 CDS EcolC_3887 NC_010468.1 4262336 4265695 R KEGG: lpf:lpl2493 hypothetical protein; hypothetical protein complement(4262336..4265695) Escherichia coli ATCC 8739 6064354 YP_001726817.1 CDS EcolC_3888 NC_010468.1 4265907 4267559 D KEGG: hso:HS_0451 hypothetical protein; hypothetical protein 4265907..4267559 Escherichia coli ATCC 8739 6064356 YP_001726818.1 CDS EcolC_3889 NC_010468.1 4267566 4268273 D KEGG: hso:HS_0452 hypothetical protein; hypothetical protein 4267566..4268273 Escherichia coli ATCC 8739 6064357 YP_001726819.1 CDS EcolC_3890 NC_010468.1 4268277 4269380 D KEGG: hso:HS_0453 hypothetical protein; hypothetical protein 4268277..4269380 Escherichia coli ATCC 8739 6064358 YP_001726820.1 CDS EcolC_3891 NC_010468.1 4269611 4269889 D KEGG: sfv:SFV_4217 hypothetical protein; hypothetical protein 4269611..4269889 Escherichia coli ATCC 8739 6064362 YP_001726821.1 CDS EcolC_3892 NC_010468.1 4269935 4270915 D PFAM: transposase IS4 family protein; KEGG: kpn:KPN_pKPN3p05895 IS5 transposase; transposase IS4 family protein 4269935..4270915 Escherichia coli ATCC 8739 6064612 YP_001726822.1 CDS EcolC_3893 NC_010468.1 4271543 4272240 D PFAM: Insertion element protein; KEGG: kpn:KPN_02839 insertion element protein; insertion element protein join(4271543..4271797,4271797..4272240) Escherichia coli ATCC 8739 6064363 YP_001726823.1 CDS EcolC_3894 NC_010468.1 4272533 4274071 D regulates the cadBA operon; DNA-binding transcriptional activator CadC 4272533..4274071 Escherichia coli ATCC 8739 6064367 YP_001726824.1 CDS cadB NC_010468.1 4274436 4275770 D antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4274436..4275770 Escherichia coli ATCC 8739 6064368 YP_001726825.1 CDS EcolC_3896 NC_010468.1 4275850 4277997 D PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: kpn:KPN_00500 lysine decarboxylase 1; lysine decarboxylase 4275850..4277997 Escherichia coli ATCC 8739 6064369 YP_001726826.1 CDS EcolC_3897 NC_010468.1 4278056 4279513 D KEGG: ssn:SSON_4307 putative peptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; amino acid/peptide transporter 4278056..4279513 Escherichia coli ATCC 8739 6064372 YP_001726827.1 CDS EcolC_3898 NC_010468.1 4279750 4281267 D class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4279750..4281267 Escherichia coli ATCC 8739 6064373 YP_001726828.1 CDS EcolC_3899 NC_010468.1 4281386 4281559 R KEGG: spt:SPA1272 putative inner membrane protein; putative inner membrane protein complement(4281386..4281559) Escherichia coli ATCC 8739 6064374 YP_001726829.1 CDS EcolC_3900 NC_010468.1 4282110 4282382 R KEGG: sdy:SDY_4240 hypothetical protein; hypothetical protein complement(4282110..4282382) Escherichia coli ATCC 8739 6064375 YP_001726830.1 CDS EcolC_3901 NC_010468.1 4282394 4282624 R PFAM: protein of unknown function DUF1271; KEGG: ssn:SSON_4303 hypothetical protein; hypothetical protein complement(4282394..4282624) Escherichia coli ATCC 8739 6064376 YP_001726831.1 CDS EcolC_3902 NC_010468.1 4282805 4284436 D C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4282805..4284436 Escherichia coli ATCC 8739 6064377 YP_001726832.1 CDS EcolC_3903 NC_010468.1 4284433 4285152 D response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4284433..4285152 Escherichia coli ATCC 8739 6064378 YP_001726833.1 CDS EcolC_3904 NC_010468.1 4285723 4287063 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4285723..4287063 Escherichia coli ATCC 8739 6064380 YP_001726834.1 CDS EcolC_3905 NC_010468.1 4287141 4288787 D TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sdy:SDY_4231 fumarase B; tartrate/fumarate subfamily Fe-S type hydro-lyase subunit beta 4287141..4288787 Escherichia coli ATCC 8739 6064381 YP_001726835.1 CDS EcolC_3906 NC_010468.1 4288910 4289539 D KEGG: sbo:SBO_4325 hypothetical protein; hypothetical protein 4288910..4289539 Escherichia coli ATCC 8739 6064383 YP_001726836.1 CDS EcolC_3907 NC_010468.1 4289678 4291099 R TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; KEGG: sfv:SFV_4110 melibiose permease II; melibiose:sodium symporter complement(4289678..4291099) Escherichia coli ATCC 8739 6064384 YP_001726837.1 CDS EcolC_3908 NC_010468.1 4291202 4292557 R PFAM: glycoside hydrolase family 4; KEGG: ssn:SSON_4294 alpha-galactosidase; glycoside hydrolase family protein complement(4291202..4292557) Escherichia coli ATCC 8739 6064385 YP_001726838.1 CDS EcolC_3909 NC_010468.1 4292840 4293748 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_4145 regulator of melibiose operon; DNA-binding transcriptional regulator MelR 4292840..4293748 Escherichia coli ATCC 8739 6064386 YP_001726839.1 CDS EcolC_3910 NC_010468.1 4293944 4296214 D PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sdy:SDY_4094 biodegradative arginine decarboxylase; arginine decarboxylase 4293944..4296214 Escherichia coli ATCC 8739 6064388 YP_001726840.1 CDS EcolC_3911 NC_010468.1 4296539 4297300 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_4097 putative AraC-type regulatory protein; AraC family transcriptional regulator 4296539..4297300 Escherichia coli ATCC 8739 6064392 YP_001726841.1 CDS EcolC_3912 NC_010468.1 4297437 4298774 D PFAM: amino acid permease-associated region; KEGG: ssn:SSON_4290 putative amino acid/amine transport protein, cryptic; arginine:agmatin antiporter 4297437..4298774 Escherichia coli ATCC 8739 6064394 YP_001726842.1 CDS EcolC_3913 NC_010468.1 4298878 4300521 D with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein 4298878..4300521 Escherichia coli ATCC 8739 6064395 YP_001726843.1 CDS EcolC_3914 NC_010468.1 4300518 4301186 D response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4300518..4301186 Escherichia coli ATCC 8739 6064397 YP_001726844.1 CDS EcolC_3915 NC_010468.1 4301187 4302287 D PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sbo:SBO_4139 sensor protein for BasR; sensor protein BasS/PmrB 4301187..4302287 Escherichia coli ATCC 8739 6064398 YP_001726845.1 CDS EcolC_3916 NC_010468.1 4302464 4303966 R TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; Osmosensory transporter coiled coil; KEGG: sdy:SDY_4102 proline permease II; proline/glycine betaine transporter complement(4302464..4303966) Escherichia coli ATCC 8739 6064399 YP_001726846.1 CDS EcolC_3917 NC_010468.1 4304230 4305108 R KEGG: sfv:SFV_4120 hypothetical protein; hypothetical protein complement(4304230..4305108) Escherichia coli ATCC 8739 6064400 YP_001726847.1 CDS EcolC_3919 NC_010468.1 4307735 4308070 D TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: sdy:SDY_4109 hypothetical protein; hypothetical protein 4307735..4308070 Escherichia coli ATCC 8739 6064402 YP_001726848.1 CDS EcolC_3920 NC_010468.1 4308228 4308671 D PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: sbo:SBO_4132 hypothetical protein; hypothetical protein 4308228..4308671 Escherichia coli ATCC 8739 6064403 YP_001726849.1 CDS EcolC_3921 NC_010468.1 4308804 4309592 D KEGG: ssn:SSON_4281 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; phosphonate/organophosphate ester transporter subunit 4308804..4309592 Escherichia coli ATCC 8739 6064405 YP_001726850.1 CDS EcolC_3922 NC_010468.1 4309617 4310633 D TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; phosphonate ABC transporter, periplasmic phosphonate binding protein; KEGG: sbo:SBO_4130 periplasmic binding protein component of Pn transporter; phosphonate ABC transporter periplasmic phosphonate binding protein 4309617..4310633 Escherichia coli ATCC 8739 6064406 YP_001726851.1 CDS EcolC_3923 NC_010468.1 4310739 4311518 D TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdy:SDY_4113 membrane channel protein component of Pn transporter; phosphonate ABC transporter inner membrane protein 4310739..4311518 Escherichia coli ATCC 8739 6064407 YP_001726852.1 CDS EcolC_3924 NC_010468.1 4311539 4312264 D may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4311539..4312264 Escherichia coli ATCC 8739 6064408 YP_001726853.1 CDS EcolC_3925 NC_010468.1 4312265 4312717 D TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: ssn:SSON_4277 phosphonate metabolism; phosphonate C-P lyase system protein PhnG 4312265..4312717 Escherichia coli ATCC 8739 6064410 YP_001726854.1 CDS phnH NC_010468.1 4312714 4313298 D TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: sdy:SDY_4116 phosphonate metabolism; carbon-phosphorus lyase complex subunit 4312714..4313298 Escherichia coli ATCC 8739 6064412 YP_001726855.1 CDS EcolC_3927 NC_010468.1 4313298 4314362 D PFAM: phosphonate metabolism; KEGG: ssn:SSON_4275 phosphonate metabolism; phosphonate metabolism protein 4313298..4314362 Escherichia coli ATCC 8739 6064415 YP_001726856.1 CDS EcolC_3928 NC_010468.1 4314355 4315200 D PFAM: phosphonate metabolism PhnJ; KEGG: sbo:SBO_4124 PhnJ; phosphonate metabolism PhnJ 4314355..4315200 Escherichia coli ATCC 8739 6064416 YP_001726857.1 CDS phnK NC_010468.1 4315197 4315955 D KEGG: ssn:SSON_4273 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase; phosphonate C-P lyase system protein PhnK 4315197..4315955 Escherichia coli ATCC 8739 6064417 YP_001726858.1 CDS EcolC_3930 NC_010468.1 4316066 4316746 D KEGG: sdy:SDY_4120 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase; phosphonate C-P lyase system protein PhnL 4316066..4316746 Escherichia coli ATCC 8739 6064420 YP_001726859.1 CDS EcolC_3931 NC_010468.1 4316743 4317879 D TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: ssn:SSON_4271 phosphonate metabolism; phosphonate metabolism protein PhnM 4316743..4317879 Escherichia coli ATCC 8739 6064421 YP_001726860.1 CDS EcolC_3932 NC_010468.1 4317879 4318436 D TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: ssn:SSON_4270 ATP-binding component of phosphonate transport; ribose 1,5-bisphosphokinase 4317879..4318436 Escherichia coli ATCC 8739 6064422 YP_001726861.1 CDS EcolC_3933 NC_010468.1 4318423 4318857 D PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4318423..4318857 Escherichia coli ATCC 8739 6064423 YP_001726862.1 CDS phnP NC_010468.1 4318859 4319617 D required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4318859..4319617 Escherichia coli ATCC 8739 6064424 YP_001726863.1 CDS EcolC_3935 NC_010468.1 4319764 4320093 R KEGG: sbo:SBO_4117 hypothetical protein; hypothetical protein complement(4319764..4320093) Escherichia coli ATCC 8739 6064425 YP_001726864.1 CDS EcolC_3936 NC_010468.1 4320162 4320611 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(4320162..4320611) Escherichia coli ATCC 8739 6064429 YP_001726865.1 CDS EcolC_3937 NC_010468.1 4320970 4321860 D involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4320970..4321860 Escherichia coli ATCC 8739 6064431 YP_001726866.1 CDS EcolC_3938 NC_010468.1 4321919 4322854 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: cko:CKO_03785 hypothetical protein; D-allose transporter subunit 4321919..4322854 Escherichia coli ATCC 8739 6064433 YP_001726867.1 CDS EcolC_3939 NC_010468.1 4322981 4324513 D with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4322981..4324513 Escherichia coli ATCC 8739 6064434 YP_001726868.1 CDS EcolC_3940 NC_010468.1 4324492 4325472 D PFAM: inner-membrane translocator; KEGG: cko:CKO_03787 hypothetical protein; D-allose transporter subunit 4324492..4325472 Escherichia coli ATCC 8739 6064439 YP_001726869.1 CDS EcolC_3941 NC_010468.1 4325483 4326178 D PFAM: ribulose-phosphate 3-epimerase; KEGG: cko:CKO_03788 hypothetical protein; allulose-6-phosphate 3-epimerase 4325483..4326178 Escherichia coli ATCC 8739 6064441 YP_001726870.1 CDS EcolC_3942 NC_010468.1 4326162 4327091 D PFAM: ROK family protein; KEGG: cko:CKO_03789 hypothetical protein; D-allose kinase 4326162..4327091 Escherichia coli ATCC 8739 6064442 YP_001726871.1 CDS EcolC_3943 NC_010468.1 4327364 4329349 D PFAM: beta-lactamase domain protein; KEGG: ssn:SSON_4265 hypothetical protein; beta-lactamase domain-containing protein 4327364..4329349 Escherichia coli ATCC 8739 6064452 YP_001726872.1 CDS EcolC_3944 NC_010468.1 4329558 4329833 D KEGG: sbo:SBO_4114 formate dehydrogenase H; formate dehydrogenase H 4329558..4329833 Escherichia coli ATCC 8739 6064453 YP_001726873.1 CDS EcolC_3945 NC_010468.1 4329852 4330883 D with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4329852..4330883 Escherichia coli ATCC 8739 6064455 YP_001726874.1 CDS EcolC_3946 NC_010468.1 4330883 4332934 D possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4330883..4332934 Escherichia coli ATCC 8739 6064458 YP_001726875.1 CDS EcolC_3947 NC_010468.1 4332931 4334397 D part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP 4332931..4334397 Escherichia coli ATCC 8739 6064459 YP_001726876.1 CDS EcolC_3948 NC_010468.1 4334595 4336742 D Contains selenocysteine; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: spt:SPA4103 formate dehydrogenase H; formate dehydrogenase subunit alpha 4334595..4336742 Escherichia coli ATCC 8739 6064462 YP_001726877.1 CDS EcolC_3949 NC_010468.1 4336836 4337525 D PFAM: Sel1 domain protein repeat-containing protein; KEGG: ssn:SSON_4259 hypothetical protein; Sel1 domain-containing protein 4336836..4337525 Escherichia coli ATCC 8739 6064463 YP_001726878.1 CDS gltP NC_010468.1 4338055 4339368 R carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter complement(4338055..4339368) Escherichia coli ATCC 8739 6064465 YP_001726879.1 CDS EcolC_3951 NC_010468.1 4339710 4340306 R PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sfv:SFV_4135 part of formate-dependent nitrite reductase complex; formate-dependent nitrite reductase complex subunit NrfG complement(4339710..4340306) Escherichia coli ATCC 8739 6064466 YP_001726880.1 CDS EcolC_3952 NC_010468.1 4340303 4340686 R TIGRFAM: cytochrome c nitrite reductase, accessory protein NrfF; PFAM: cytochrome C biogenesis protein; KEGG: sbo:SBO_4106 NrfG; formate-dependent nitrite reductase complex subunit NrfF complement(4340303..4340686) Escherichia coli ATCC 8739 6064468 YP_001726881.1 CDS EcolC_3953 NC_010468.1 4340679 4342301 R with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE complement(4340679..4342301) Escherichia coli ATCC 8739 6064469 YP_001726882.1 CDS EcolC_3954 NC_010468.1 4342417 4343373 R TIGRFAM: cytochrome c nitrite reductase, NrfD subunit; PFAM: Polysulphide reductase NrfD; KEGG: ssn:SSON_4254 formate-dependent nitrate reductase complex transmembrane protein; cytochrome c nitrite reductase subunit NrfD complement(4342417..4343373) Escherichia coli ATCC 8739 6064470 YP_001726883.1 CDS EcolC_3955 NC_010468.1 4343370 4344041 R TIGRFAM: cytochrome c nitrite reductase, Fe-S protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_4103 formate-dependent nitrite reductase complex Fe-S centers; cytochrome c nitrite reductase, Fe-S protein complement(4343370..4344041) Escherichia coli ATCC 8739 6064471 YP_001726884.1 CDS EcolC_3956 NC_010468.1 4344038 4344604 R part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit complement(4344038..4344604) Escherichia coli ATCC 8739 6064472 YP_001726885.1 CDS nrfA NC_010468.1 4344649 4346085 R catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 complement(4344649..4346085) Escherichia coli ATCC 8739 6064480 YP_001726886.1 CDS EcolC_3958 NC_010468.1 4346478 4348436 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4346478..4348436 Escherichia coli ATCC 8739 6064481 YP_001726887.1 CDS EcolC_3959 NC_010468.1 4348637 4348951 D PFAM: protein of unknown function DUF485; KEGG: sbo:SBO_4099 hypothetical protein; hypothetical protein 4348637..4348951 Escherichia coli ATCC 8739 6064482 YP_001726888.1 CDS actP NC_010468.1 4348948 4350597 D member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4348948..4350597 Escherichia coli ATCC 8739 6064485 YP_001726889.1 CDS EcolC_3961 NC_010468.1 4351067 4352068 D PFAM: pentapeptide repeat protein; KEGG: sfx:S3593 hypothetical protein; pentapeptide repeat-containing protein 4351067..4352068 Escherichia coli ATCC 8739 6064488 YP_001726890.1 CDS EcolC_3962 NC_010468.1 4352222 4353871 R TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: sdy:SDY_4502 hypothetical protein; Na+/H+ antiporter complement(4352222..4353871) Escherichia coli ATCC 8739 6064489 YP_001726891.1 CDS EcolC_3963 NC_010468.1 4354023 4355372 R PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sdy:SDY_4503 hypothetical protein; xanthine/uracil/vitamin C permease complement(4354023..4355372) Escherichia coli ATCC 8739 6064490 YP_001726892.1 CDS EcolC_3964 NC_010468.1 4355918 4356382 R TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: sdy:SDY_4504 redox-sensing activator of SoxS; MerR family transcriptional regulator complement(4355918..4356382) Escherichia coli ATCC 8739 6064495 YP_001726893.1 CDS EcolC_3965 NC_010468.1 4356468 4356791 D regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4356468..4356791 Escherichia coli ATCC 8739 6064496 YP_001726894.1 CDS EcolC_3966 NC_010468.1 4356794 4358380 R PFAM: EAL domain protein; KEGG: sfv:SFV_4151 hypothetical protein; EAL domain-containing protein complement(4356794..4358380) Escherichia coli ATCC 8739 6064501 YP_001726895.1 CDS EcolC_3967 NC_010468.1 4358810 4359091 D KEGG: sbo:SBO_4092 hypothetical protein; hypothetical protein 4358810..4359091 Escherichia coli ATCC 8739 6064502 YP_001726896.1 CDS EcolC_3968 NC_010468.1 4359190 4359726 R binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein complement(4359190..4359726) Escherichia coli ATCC 8739 6064503 YP_001726897.1 CDS uvrA NC_010468.1 4359981 4362803 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4359981..4362803 Escherichia coli ATCC 8739 6064504 YP_001726898.1 CDS EcolC_3970 NC_010468.1 4362838 4363194 R PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_4510 hypothetical protein; hypothetical protein complement(4362838..4363194) Escherichia coli ATCC 8739 6064505 YP_001726899.1 CDS EcolC_3971 NC_010468.1 4363198 4363614 R PFAM: protein of unknown function UPF0047; KEGG: sdy:SDY_4511 hypothetical protein; hypothetical protein complement(4363198..4363614) Escherichia coli ATCC 8739 6064506 YP_001726900.1 CDS aphA NC_010468.1 4363725 4364438 R Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase complement(4363725..4364438) Escherichia coli ATCC 8739 6064507 YP_001726901.1 CDS EcolC_3973 NC_010468.1 4364840 4365226 D KEGG: sbo:SBO_4083 hypothetical protein; hypothetical protein 4364840..4365226 Escherichia coli ATCC 8739 6064509 YP_001726902.1 CDS EcolC_3974 NC_010468.1 4365565 4366758 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(4365565..4366758) Escherichia coli ATCC 8739 6064510 YP_001726903.1 CDS alr NC_010468.1 4367011 4368090 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(4367011..4368090) Escherichia coli ATCC 8739 6064511 YP_001726904.1 CDS EcolC_3976 NC_010468.1 4368143 4369558 R unwinds double stranded DNA; replicative DNA helicase complement(4368143..4369558) Escherichia coli ATCC 8739 6064512 YP_001726905.1 CDS EcolC_3977 NC_010468.1 4369641 4370624 D PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_4523 quinone oxidoreductase; NADPH-dependent quinone oxidoreductase 4369641..4370624 Escherichia coli ATCC 8739 6064513 YP_001726906.1 CDS pspG NC_010468.1 4370790 4371032 R coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G complement(4370790..4371032) Escherichia coli ATCC 8739 6064514 YP_001726907.1 CDS EcolC_3979 NC_010468.1 4371166 4372203 R TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: ssn:SSON_4229 hypothetical protein; tRNA-dihydrouridine synthase A complement(4371166..4372203) Escherichia coli ATCC 8739 6064516 YP_001726908.1 CDS EcolC_3980 NC_010468.1 4372566 4373312 R KEGG: sfv:SFV_4165 hypothetical protein; hypothetical protein complement(4372566..4373312) Escherichia coli ATCC 8739 6064519 YP_001726909.1 CDS EcolC_3981 NC_010468.1 4373303 4373587 R KEGG: sfl:SF4158 hypothetical protein; hypothetical protein complement(4373303..4373587) Escherichia coli ATCC 8739 6064520 YP_001726910.1 CDS EcolC_3982 NC_010468.1 4373906 4374421 D Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4373906..4374421 Escherichia coli ATCC 8739 6064524 YP_001726911.1 CDS EcolC_3983 NC_010468.1 4374463 4374672 R unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein complement(4374463..4374672) Escherichia coli ATCC 8739 6064525 YP_001726912.1 CDS EcolC_3984 NC_010468.1 4374788 4376167 R TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sfv:SFV_4169 DNA-damage-inducible protein F; DNA-damage-inducible SOS response protein complement(4374788..4376167) Escherichia coli ATCC 8739 6064527 YP_001726913.1 CDS EcolC_3985 NC_010468.1 4376186 4376794 R Represses a number of genes involved in the response to DNA damage; LexA repressor complement(4376186..4376794) Escherichia coli ATCC 8739 6064528 YP_001726914.1 CDS EcolC_3986 NC_010468.1 4376904 4377272 R PFAM: diacylglycerol kinase; KEGG: sdy:SDY_4532 diacylglycerol kinase; diacylglycerol kinase complement(4376904..4377272) Escherichia coli ATCC 8739 6064529 YP_001726915.1 CDS EcolC_3987 NC_010468.1 4377443 4379866 D PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4377443..4379866 Escherichia coli ATCC 8739 6064530 YP_001726916.1 CDS ubiA NC_010468.1 4380021 4380893 R catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase complement(4380021..4380893) Escherichia coli ATCC 8739 6064531 YP_001726917.1 CDS ubiC NC_010468.1 4380906 4381403 R catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase complement(4380906..4381403) Escherichia coli ATCC 8739 6064533 YP_001726918.1 CDS EcolC_3992 NC_010468.1 4383435 4384355 R PFAM: Maltose operon periplasmic; KEGG: ssn:SSON_4215 periplasmic protein of mal regulon; maltose regulon periplasmic protein complement(4383435..4384355) Escherichia coli ATCC 8739 6064535 YP_001726919.1 CDS lamB NC_010468.1 4384598 4385938 R porin involved in the transport of maltose and maltodextrins; maltoporin complement(4384598..4385938) Escherichia coli ATCC 8739 6064537 YP_001726920.1 CDS EcolC_3994 NC_010468.1 4386010 4387125 R with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein complement(4386010..4387125) Escherichia coli ATCC 8739 6064539 YP_001726921.1 CDS malE NC_010468.1 4387490 4388680 D functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4387490..4388680 Escherichia coli ATCC 8739 6064542 YP_001726922.1 CDS malF NC_010468.1 4388834 4390378 D with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4388834..4390378 Escherichia coli ATCC 8739 6064546 YP_001726923.1 CDS malG NC_010468.1 4390393 4391283 D with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4390393..4391283 Escherichia coli ATCC 8739 6064547 YP_001726924.1 CDS xylE NC_010468.1 4391655 4393130 D xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 4391655..4393130 Escherichia coli ATCC 8739 6064548 YP_001726925.1 CDS EcolC_3999 NC_010468.1 4393174 4393584 R PFAM: phosphate-starvation-inducible E; KEGG: sdy:SDY_4218 hypothetical protein; phosphate-starvation-inducible protein PsiE complement(4393174..4393584) Escherichia coli ATCC 8739 6064550 YP_001726926.1 CDS EcolC_4000 NC_010468.1 4394014 4394175 R hypothetical protein complement(4394014..4394175) Escherichia coli ATCC 8739 6064551 YP_001726927.1 CDS EcolC_4001 NC_010468.1 4394179 4396275 R PFAM: protein of unknown function DUF940 membrane lipoprotein putative; KEGG: sbo:SBO_4057 hypothetical protein; hypothetical protein complement(4394179..4396275) Escherichia coli ATCC 8739 6064552 YP_001726928.1 CDS EcolC_4002 NC_010468.1 4396275 4397012 R PFAM: protein of unknown function DUF1017; KEGG: sdy:SDY_4220 hypothetical protein; hypothetical protein complement(4396275..4397012) Escherichia coli ATCC 8739 6064554 YP_001726929.1 CDS EcolC_4003 NC_010468.1 4397009 4397647 R KEGG: ssn:SSON_4205 hypothetical protein; hypothetical protein complement(4397009..4397647) Escherichia coli ATCC 8739 6064556 YP_001726930.1 CDS EcolC_4004 NC_010468.1 4397762 4398004 R KEGG: sdy:SDY_4222 hypothetical protein; hypothetical protein complement(4397762..4398004) Escherichia coli ATCC 8739 6064557 YP_001726931.1 CDS pgi NC_010468.1 4398516 4400165 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(4398516..4400165) Escherichia coli ATCC 8739 6064558 YP_001726932.1 CDS EcolC_4006 NC_010468.1 4400690 4402039 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4400690..4402039 Escherichia coli ATCC 8739 6064559 YP_001726933.1 CDS EcolC_4007 NC_010468.1 4402292 4402564 D KEGG: sdy:SDY_4309 hypothetical protein; hypothetical protein 4402292..4402564 Escherichia coli ATCC 8739 6064560 YP_001726934.1 CDS EcolC_4008 NC_010468.1 4402697 4403569 R catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F complement(4402697..4403569) Escherichia coli ATCC 8739 6064561 YP_001726935.1 CDS EcolC_4009 NC_010468.1 4403781 4404470 D alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4403781..4404470 Escherichia coli ATCC 8739 6064563 YP_001726936.1 CDS EcolC_4010 NC_010468.1 4404561 4406192 R TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; KEGG: ssn:SSON_4191 putative alpha helix protein; sodium-dependent inorganic phosphate (Pi) transporter complement(4404561..4406192) Escherichia coli ATCC 8739 6064565 YP_001726937.1 CDS metH NC_010468.1 4406412 4410095 R one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase complement(4406412..4410095) Escherichia coli ATCC 8739 6064566 YP_001726938.1 CDS EcolC_4012 NC_010468.1 4410295 4411119 D regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4410295..4411119 Escherichia coli ATCC 8739 6064567 YP_001726939.1 CDS EcolC_4013 NC_010468.1 4411436 4413010 D PFAM: ShET2 enterotoxin domain protein; KEGG: yps:YPTB3305 enterotoxin-like protein; ShET2 enterotoxin domain-containing protein 4411436..4413010 Escherichia coli ATCC 8739 6064568 YP_001726940.1 CDS aceK NC_010468.1 4412979 4414715 R catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein complement(4412979..4414715) Escherichia coli ATCC 8739 6064569 YP_001726941.1 CDS EcolC_4015 NC_010468.1 4414996 4416300 R TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sdy:SDY_4328 isocitrate lyase; isocitrate lyase complement(4414996..4416300) Escherichia coli ATCC 8739 6064570 YP_001726942.1 CDS EcolC_4016 NC_010468.1 4416330 4417931 R Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase complement(4416330..4417931) Escherichia coli ATCC 8739 6064573 YP_001726943.1 CDS EcolC_4017 NC_010468.1 4418200 4419129 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(4418200..4419129) Escherichia coli ATCC 8739 6064575 YP_001726944.1 CDS EcolC_4018 NC_010468.1 4419286 4419729 D PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_4083 hypothetical protein; hypothetical protein 4419286..4419729 Escherichia coli ATCC 8739 6064576 YP_001726945.1 CDS purH NC_010468.1 4425743 4427332 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4425743..4427332 Escherichia coli ATCC 8739 6064586 YP_001726946.1 CDS EcolC_4020 NC_010468.1 4427344 4428633 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4427344..4428633 Escherichia coli ATCC 8739 6064592 YP_001726947.1 CDS EcolC_4021 NC_010468.1 4428630 4429955 R DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR complement(4428630..4429955) Escherichia coli ATCC 8739 6064594 YP_001726948.1 CDS EcolC_4022 NC_010468.1 4429952 4431328 R PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfx:S3660 sensor kinase for HydG, hydrogenase 3 activity; sensor protein ZraS complement(4429952..4431328) Escherichia coli ATCC 8739 6064595 YP_001726949.1 CDS zraP NC_010468.1 4431566 4431985 D KEGG: sdy:SDY_3724 hypothetical protein; zinc resistance protein 4431566..4431985 Escherichia coli ATCC 8739 6064596 YP_001726950.1 CDS EcolC_4024 NC_010468.1 4431987 4432622 R PFAM: protein of unknown function DUF1481; KEGG: sdy:SDY_3725 hypothetical protein; hypothetical protein complement(4431987..4432622) Escherichia coli ATCC 8739 6064599 YP_001726951.1 CDS EcolC_4025 NC_010468.1 4432695 4432967 R histone-like DNA-binding protein; transcriptional regulator HU subunit alpha complement(4432695..4432967) Escherichia coli ATCC 8739 6064600 YP_001726952.1 CDS EcolC_4026 NC_010468.1 4433154 4433744 R PFAM: protein of unknown function DUF416; KEGG: ssn:SSON_4172 hypothetical protein; hypothetical protein complement(4433154..4433744) Escherichia coli ATCC 8739 6064601 YP_001726953.1 CDS EcolC_4027 NC_010468.1 4433787 4434458 R Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V complement(4433787..4434458) Escherichia coli ATCC 8739 6064618 YP_001726954.1 CDS hemE NC_010468.1 4434468 4435532 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(4434468..4435532) Escherichia coli ATCC 8739 6064627 YP_001726955.1 CDS nudC NC_010468.1 4435572 4436345 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(4435572..4436345) Escherichia coli ATCC 8739 6064634 YP_001726956.1 CDS EcolC_4030 NC_010468.1 4436440 4436916 D binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4436440..4436916 Escherichia coli ATCC 8739 6064635 YP_001726957.1 CDS EcolC_4031 NC_010468.1 4437150 4439045 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4437150..4439045 Escherichia coli ATCC 8739 6064650 YP_001726958.1 CDS EcolC_4032 NC_010468.1 4439045 4439680 D catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4439045..4439680 Escherichia coli ATCC 8739 6064671 YP_001726959.1 CDS EcolC_4033 NC_010468.1 4439673 4440428 D TIGRFAM: thiazole biosynthesis adenylyltransferase ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sfv:SFV_4064 thiamin biosynthesis, thiazole moiety; thiazole biosynthesis adenylyltransferase ThiF 4439673..4440428 Escherichia coli ATCC 8739 6064697 YP_001726960.1 CDS EcolC_4034 NC_010468.1 4440412 4440612 D with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4440412..4440612 Escherichia coli ATCC 8739 6064708 YP_001726961.1 CDS thiG NC_010468.1 4440614 4441384 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4440614..4441384 Escherichia coli ATCC 8739 6064712 YP_001726962.1 CDS thiH NC_010468.1 4441381 4442514 D in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4441381..4442514 Escherichia coli ATCC 8739 6064718 YP_001726963.1 CDS EcolC_4037 NC_010468.1 4442756 4446979 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(4442756..4446979) Escherichia coli ATCC 8739 6064719 YP_001726964.1 CDS rpoB NC_010468.1 4447056 4451084 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(4447056..4451084) Escherichia coli ATCC 8739 6064720 YP_001726965.1 CDS rplL NC_010468.1 4451404 4451769 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(4451404..4451769) Escherichia coli ATCC 8739 6064731 YP_001726966.1 CDS rplJ NC_010468.1 4451836 4452333 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(4451836..4452333) Escherichia coli ATCC 8739 6064740 YP_001726967.1 CDS rplA NC_010468.1 4452746 4453450 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(4452746..4453450) Escherichia coli ATCC 8739 6064743 YP_001726968.1 CDS rplK NC_010468.1 4453454 4453882 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(4453454..4453882) Escherichia coli ATCC 8739 6064748 YP_001726969.1 CDS nusG NC_010468.1 4454041 4454586 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(4454041..4454586) Escherichia coli ATCC 8739 6064756 YP_001726970.1 CDS secE NC_010468.1 4454588 4454971 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(4454588..4454971) Escherichia coli ATCC 8739 6064757 YP_001726971.1 CDS EcolC_4045 NC_010468.1 4455201 4456385 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(4455201..4456385) Escherichia coli ATCC 8739 6064769 YP_001726972.1 CDS EcolC_4046 NC_010468.1 4457327 4458253 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4457327..4458253 Escherichia coli ATCC 8739 6064950 YP_001726973.1 CDS EcolC_4047 NC_010468.1 4458282 4459247 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(4458282..4459247) Escherichia coli ATCC 8739 6065006 YP_001726974.1 CDS murB NC_010468.1 4459244 4460272 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(4459244..4460272) Escherichia coli ATCC 8739 6065008 YP_001726975.1 CDS EcolC_4049 NC_010468.1 4465789 4466577 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(4465789..4466577) Escherichia coli ATCC 8739 6065124 YP_001726976.1 CDS btuB NC_010468.1 4466591 4468435 R involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter complement(4466591..4468435) Escherichia coli ATCC 8739 6065161 YP_001726977.1 CDS EcolC_4051 NC_010468.1 4468804 4469904 D catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4468804..4469904 Escherichia coli ATCC 8739 6065170 YP_001726978.1 CDS EcolC_4052 NC_010468.1 4469944 4470303 R PFAM: protein of unknown function DUF1422; KEGG: sbo:SBO_3983 hypothetical protein; hypothetical protein complement(4469944..4470303) Escherichia coli ATCC 8739 6065188 YP_001726979.1 CDS EcolC_4053 NC_010468.1 4470303 4471007 R negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR complement(4470303..4471007) Escherichia coli ATCC 8739 6065202 YP_001726980.1 CDS EcolC_4054 NC_010468.1 4471284 4472684 D catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4471284..4472684 Escherichia coli ATCC 8739 6065209 YP_001726981.1 CDS EcolC_4055 NC_010468.1 4472667 4473584 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(4472667..4473584) Escherichia coli ATCC 8739 6065212 YP_001726982.1 CDS EcolC_4056 NC_010468.1 4473851 4475224 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(4473851..4475224) Escherichia coli ATCC 8739 6065213 YP_001726983.1 CDS EcolC_4057 NC_010468.1 4475285 4476058 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(4475285..4476058) Escherichia coli ATCC 8739 6065225 YP_001726984.1 CDS argC NC_010468.1 4476069 4477073 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(4476069..4477073) Escherichia coli ATCC 8739 6065244 YP_001726985.1 CDS EcolC_4059 NC_010468.1 4477227 4478378 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4477227..4478378 Escherichia coli ATCC 8739 6065263 YP_001726986.1 CDS EcolC_4060 NC_010468.1 4478730 4481381 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4478730..4481381 Escherichia coli ATCC 8739 6065269 YP_001726987.1 CDS EcolC_4061 NC_010468.1 4481563 4483296 D PFAM: sulfatase; KEGG: sbo:SBO_3974 hypothetical protein; hypothetical protein 4481563..4483296 Escherichia coli ATCC 8739 6065290 YP_001726988.1 CDS EcolC_4062 NC_010468.1 4483511 4484362 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbo:SBO_3973 putative AraC-type regulatory protein; AraC family transcriptional regulator 4483511..4484362 Escherichia coli ATCC 8739 6065316 YP_001726989.1 CDS EcolC_4063 NC_010468.1 4484349 4484690 R FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative PTS system fructose-specific transporter subunit IIB complement(4484349..4484690) Escherichia coli ATCC 8739 6065319 YP_001726990.1 CDS EcolC_4064 NC_010468.1 4484692 4485570 R KEGG: sdy:SDY_3787 probable pyruvate formate lyase activating enzyme 2; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM domain protein; pyruvate formate lyase II activase complement(4484692..4485570) Escherichia coli ATCC 8739 6065334 YP_001726991.1 CDS pflD NC_010468.1 4485536 4487833 R involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 complement(4485536..4487833) Escherichia coli ATCC 8739 6065346 YP_001726992.1 CDS EcolC_4066 NC_010468.1 4487884 4488204 R FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB complement(4487884..4488204) Escherichia coli ATCC 8739 6065348 YP_001726993.1 CDS EcolC_4067 NC_010468.1 4488219 4489298 R FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative PTS system fructose-specific permease IIC complement(4488219..4489298) Escherichia coli ATCC 8739 6065353 YP_001726994.1 CDS EcolC_4068 NC_010468.1 4489607 4492108 D TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: cko:CKO_03046 hypothetical protein; phosphoenolpyruvate-protein phosphotransferase 4489607..4492108 Escherichia coli ATCC 8739 6065356 YP_001726995.1 CDS EcolC_4069 NC_010468.1 4492120 4492782 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4492120..4492782 Escherichia coli ATCC 8739 6065368 YP_001726996.1 CDS gldA NC_010468.1 4492793 4493896 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4492793..4493896 Escherichia coli ATCC 8739 6065380 YP_001726997.1 CDS EcolC_4071 NC_010468.1 4494171 4494788 D PFAM: protein of unknown function DUF1287; KEGG: sbo:SBO_3964 hypothetical protein; hypothetical protein 4494171..4494788 Escherichia coli ATCC 8739 6065396 YP_001726998.1 CDS EcolC_4072 NC_010468.1 4494815 4495720 R PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4117 hypothetical protein; hypothetical protein complement(4494815..4495720) Escherichia coli ATCC 8739 6065415 YP_001726999.1 CDS EcolC_4073 NC_010468.1 4495813 4497993 R TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: sfv:SFV_4012 catalase; hydroperoxidase HPI(I); catalase/peroxidase HPI complement(4495813..4497993) Escherichia coli ATCC 8739 6065444 YP_001727000.1 CDS metF NC_010468.1 4498322 4499212 R MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase complement(4498322..4499212) Escherichia coli ATCC 8739 6065481 YP_001727001.1 CDS metL NC_010468.1 4499561 4501993 R multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II complement(4499561..4501993) Escherichia coli ATCC 8739 6065484 YP_001727002.1 CDS EcolC_4076 NC_010468.1 4501996 4503156 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(4501996..4503156) Escherichia coli ATCC 8739 6065486 YP_001727003.1 CDS EcolC_4077 NC_010468.1 4503433 4503750 D when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4503433..4503750 Escherichia coli ATCC 8739 6065518 YP_001727004.1 CDS EcolC_4078 NC_010468.1 4503934 4504542 D member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase 4503934..4504542 Escherichia coli ATCC 8739 6065575 YP_001727005.1 CDS EcolC_4079 NC_010468.1 4504687 4504959 D PFAM: Insertion element protein; KEGG: sdy:SDY_P028 iso-IS1 ORF1; insertion element protein 4504687..4504959 Escherichia coli ATCC 8739 6065594 YP_001727006.1 CDS EcolC_4081 NC_010468.1 4505774 4507915 R TIGRFAM: YD repeat protein; KEGG: sbo:SBO_0563 RhsC protein in rhs element; YD repeat-containing protein complement(4505774..4507915) Escherichia coli ATCC 8739 6065604 YP_001727007.1 CDS rpmE NC_010468.1 4508075 4508287 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(4508075..4508287) Escherichia coli ATCC 8739 6065605 YP_001727008.1 CDS EcolC_4083 NC_010468.1 4508490 4510688 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4508490..4510688 Escherichia coli ATCC 8739 6065614 YP_001727009.1 CDS EcolC_4084 NC_010468.1 4510844 4511869 D negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4510844..4511869 Escherichia coli ATCC 8739 6065630 YP_001727010.1 CDS EcolC_4085 NC_010468.1 4512066 4512920 D TIGRFAM: cell division protein FtsN; PFAM: Sporulation domain protein; KEGG: sbo:SBO_3950 essential cell division protein; cell division protein FtsN 4512066..4512920 Escherichia coli ATCC 8739 6065631 YP_001727011.1 CDS EcolC_4086 NC_010468.1 4513013 4513543 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4513013..4513543 Escherichia coli ATCC 8739 6065638 YP_001727012.1 CDS hslU NC_010468.1 4513553 4514884 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4513553..4514884 Escherichia coli ATCC 8739 6065640 YP_001727013.1 CDS EcolC_4088 NC_010468.1 4514951 4515877 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4514951..4515877 Escherichia coli ATCC 8739 6065651 YP_001727014.1 CDS EcolC_4089 NC_010468.1 4515970 4516455 D regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4515970..4516455 Escherichia coli ATCC 8739 6065657 YP_001727015.1 CDS EcolC_4090 NC_010468.1 4516540 4516779 R PFAM: protein of unknown function DUF904; KEGG: sdy:SDY_3816 hypothetical protein; hypothetical protein complement(4516540..4516779) Escherichia coli ATCC 8739 6065674 YP_001727016.1 CDS EcolC_4091 NC_010468.1 4517210 4518055 D TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: ssn:SSON_4096 facilitated diffusion of glycerol; MIP family channel protein 4517210..4518055 Escherichia coli ATCC 8739 6065676 YP_001727017.1 CDS glpK NC_010468.1 4518078 4519586 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4518078..4519586 Escherichia coli ATCC 8739 6065683 YP_001727018.1 CDS glpX NC_010468.1 4519592 4520731 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4519592..4520731 Escherichia coli ATCC 8739 6065689 YP_001727019.1 CDS EcolC_4094 NC_010468.1 4520828 4521574 D PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sdy:SDY_3820 ferredoxin-NADP reductase; ferredoxin-NADP reductase 4520828..4521574 Escherichia coli ATCC 8739 6065702 YP_001727020.1 CDS EcolC_4095 NC_010468.1 4521579 4522007 R with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD complement(4521579..4522007) Escherichia coli ATCC 8739 6065704 YP_001727021.1 CDS EcolC_4096 NC_010468.1 4522034 4522333 R PFAM: conserved hypothetical protein; KEGG: ssn:SSON_4091 hypothetical protein; hypothetical protein complement(4522034..4522333) Escherichia coli ATCC 8739 6065705 YP_001727022.1 CDS EcolC_4097 NC_010468.1 4522545 4522985 R PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_4090 hypothetical protein; hypothetical protein complement(4522545..4522985) Escherichia coli ATCC 8739 6065706 YP_001727023.1 CDS EcolC_4098 NC_010468.1 4523086 4523685 D PFAM: protein of unknown function DUF1454; KEGG: sbo:SBO_3937 hypothetical protein; hypothetical protein 4523086..4523685 Escherichia coli ATCC 8739 6065717 YP_001727024.1 CDS tpiA NC_010468.1 4523793 4524560 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4523793..4524560 Escherichia coli ATCC 8739 6065754 YP_001727025.1 CDS EcolC_4100 NC_010468.1 4524615 4525370 R PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: sbo:SBO_3935 CDP-diacylglycerol phosphotidylhydrolase; CDP-diacylglycerol pyrophosphatase complement(4524615..4525370) Escherichia coli ATCC 8739 6065760 YP_001727026.1 CDS EcolC_4101 NC_010468.1 4525477 4526466 R TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_4086 periplasmic sulfate-binding protein; sulfate transporter subunit complement(4525477..4526466) Escherichia coli ATCC 8739 6065790 YP_001727027.1 CDS EcolC_4102 NC_010468.1 4526786 4527748 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(4526786..4527748) Escherichia coli ATCC 8739 6065796 YP_001727028.1 CDS fieF NC_010468.1 4527929 4528831 R member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F complement(4527929..4528831) Escherichia coli ATCC 8739 6065858 YP_001727029.1 CDS cpxP NC_010468.1 4528980 4529480 R repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP complement(4528980..4529480) Escherichia coli ATCC 8739 6065865 YP_001727030.1 CDS EcolC_4105 NC_010468.1 4529630 4530328 D response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4529630..4530328 Escherichia coli ATCC 8739 6065866 YP_001727031.1 CDS cpxA NC_010468.1 4530325 4531698 D part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4530325..4531698 Escherichia coli ATCC 8739 6065886 YP_001727032.1 CDS EcolC_4107 NC_010468.1 4531804 4532478 R PFAM: 3-alpha domain protein; MOSC domain containing protein; KEGG: sbo:SBO_3928 hypothetical protein; hypothetical protein complement(4531804..4532478) Escherichia coli ATCC 8739 6065900 YP_001727033.1 CDS EcolC_4108 NC_010468.1 4532627 4533610 R transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease complement(4532627..4533610) Escherichia coli ATCC 8739 6065901 YP_001727034.1 CDS EcolC_4109 NC_010468.1 4533870 4534490 R SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase complement(4533870..4534490) Escherichia coli ATCC 8739 6065910 YP_001727035.1 CDS EcolC_4110 NC_010468.1 4534775 4535809 D transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4534775..4535809 Escherichia coli ATCC 8739 6065918 YP_001727036.1 CDS EcolC_4111 NC_010468.1 4535806 4536744 R activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR complement(4535806..4536744) Escherichia coli ATCC 8739 6065919 YP_001727037.1 CDS EcolC_4112 NC_010468.1 4536728 4537564 R activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS complement(4536728..4537564) Escherichia coli ATCC 8739 6065922 YP_001727038.1 CDS rhaB NC_010468.1 4537852 4539321 D catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4537852..4539321 Escherichia coli ATCC 8739 6065939 YP_001727039.1 CDS EcolC_4114 NC_010468.1 4539318 4540577 D catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4539318..4540577 Escherichia coli ATCC 8739 6065949 YP_001727040.1 CDS EcolC_4115 NC_010468.1 4541028 4541852 D KEGG: ssn:SSON_4072 rhamnulose-phosphate aldolase; TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; rhamnulose-1-phosphate aldolase 4541028..4541852 Escherichia coli ATCC 8739 6065976 YP_001727041.1 CDS EcolC_4116 NC_010468.1 4541862 4542176 D TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: sfv:SFV_3594 hypothetical protein; L-rhamnose 1-epimerase 4541862..4542176 Escherichia coli ATCC 8739 6065994 YP_001727042.1 CDS EcolC_4117 NC_010468.1 4542477 4542923 D with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; putative PTS system fructose-specific transporter subunit IIA 4542477..4542923 Escherichia coli ATCC 8739 6065995 YP_001727043.1 CDS EcolC_4118 NC_010468.1 4542934 4544385 D TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS fructose-specific IIB subunit; KEGG: sbo:SBO_3915 PTS system fructose-like enzyme IIBC component; putative PTS system transporter subunits IIBC 4542934..4544385 Escherichia coli ATCC 8739 6065997 YP_001727044.1 CDS EcolC_4119 NC_010468.1 4544375 4545445 D with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; putative fructose-specific phosphotransferase system protein FrvX 4544375..4545445 Escherichia coli ATCC 8739 6066001 YP_001727045.1 CDS EcolC_4120 NC_010468.1 4545445 4547193 D putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; putative frv operon regulatory protein 4545445..4547193 Escherichia coli ATCC 8739 6066004 YP_001727046.1 CDS EcolC_4121 NC_010468.1 4547243 4548298 R KEGG: sbo:SBO_3910 hypothetical protein; hypothetical protein complement(4547243..4548298) Escherichia coli ATCC 8739 6066025 YP_001727047.1 CDS EcolC_4122 NC_010468.1 4548451 4549284 R involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein complement(4548451..4549284) Escherichia coli ATCC 8739 6066033 YP_001727048.1 CDS EcolC_4123 NC_010468.1 4549478 4552528 D PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sbo:SBO_3908 formate dehydrogenase-O, major subunit; KEGG: ssn:SSON_4063 formate dehydrogenase-O, major subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase subunit alpha 4549478..4552528 Escherichia coli ATCC 8739 6066049 YP_001727049.1 CDS EcolC_4125 NC_010468.1 4552541 4553443 D TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbo:SBO_3907 formate dehydrogenase-O, iron-sulfur subunit; formate dehydrogenase subunit beta 4552541..4553443 Escherichia coli ATCC 8739 6066050 YP_001727050.1 CDS EcolC_4126 NC_010468.1 4553440 4554075 D cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4553440..4554075 Escherichia coli ATCC 8739 6066059 YP_001727051.1 CDS EcolC_4127 NC_010468.1 4554072 4555001 D required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4554072..4555001 Escherichia coli ATCC 8739 6066100 YP_001727052.1 CDS EcolC_4128 NC_010468.1 4555331 4555573 R KEGG: sbo:SBO_3904 hypothetical protein; hypothetical protein complement(4555331..4555573) Escherichia coli ATCC 8739 6066121 YP_001727053.1 CDS EcolC_4129 NC_010468.1 4555791 4556009 R PFAM: CopG domain protein DNA-binding domain protein; KEGG: sfv:SFV_3606 hypothetical protein; CopG family transcriptional regulator complement(4555791..4556009) Escherichia coli ATCC 8739 6066174 YP_001727054.1 CDS EcolC_4130 NC_010468.1 4556861 4557802 R TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; Thioesterase putative; KEGG: sbo:SBO_3902 putative acetyltransferase; thioesterase domain-containing protein complement(4556861..4557802) Escherichia coli ATCC 8739 6066193 YP_001727055.1 CDS EcolC_4131 NC_010468.1 4557847 4558284 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(4557847..4558284) Escherichia coli ATCC 8739 6066199 YP_001727056.1 CDS rbn NC_010468.1 4558281 4559153 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN complement(4558281..4559153) Escherichia coli ATCC 8739 6066201 YP_001727057.1 CDS EcolC_4133 NC_010468.1 4559147 4559746 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ssn:SSON_4054 putative phosphatase; phosphatase complement(4559147..4559746) Escherichia coli ATCC 8739 6066216 YP_001727058.1 CDS EcolC_4134 NC_010468.1 4559887 4560774 R PFAM: Aldose 1-epimerase; KEGG: sbo:SBO_3898 hypothetical protein; aldose 1-epimerase complement(4559887..4560774) Escherichia coli ATCC 8739 6066225 YP_001727059.1 CDS EcolC_4135 NC_010468.1 4560764 4562113 R PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4052 putative transport protein shikimate; general substrate transporter complement(4560764..4562113) Escherichia coli ATCC 8739 6066227 YP_001727060.1 CDS EcolC_4136 NC_010468.1 4562212 4563645 R PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4051 putative transporter; major facilitator transporter complement(4562212..4563645) Escherichia coli ATCC 8739 6066230 YP_001727061.1 CDS EcolC_4137 NC_010468.1 4563715 4564725 R PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_4050 putative dehydrogenase; alcohol dehydrogenase complement(4563715..4564725) Escherichia coli ATCC 8739 6066242 YP_001727062.1 CDS EcolC_4138 NC_010468.1 4564758 4565645 R PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ssn:SSON_4049 putative aldolase; deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase complement(4564758..4565645) Escherichia coli ATCC 8739 6066243 YP_001727063.1 CDS EcolC_4139 NC_010468.1 4565670 4566548 R PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ssn:SSON_4048 putative dehydrogenase; 3-hydroxyisobutyrate dehydrogenase complement(4565670..4566548) Escherichia coli ATCC 8739 6066245 YP_001727064.1 CDS EcolC_4140 NC_010468.1 4566721 4567617 D PFAM: PfkB domain protein; KEGG: sbo:SBO_3886 putative kinase; ribokinase-like domain-containing protein 4566721..4567617 Escherichia coli ATCC 8739 6066259 YP_001727065.1 CDS EcolC_4141 NC_010468.1 4567657 4568445 D PFAM: regulatory protein GntR HTH; regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: ssn:SSON_4045 putative DeoR-type transcriptional regulator; DeoR family transcriptional regulator 4567657..4568445 Escherichia coli ATCC 8739 6066268 YP_001727066.1 CDS EcolC_4142 NC_010468.1 4568556 4569821 R PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3626 putative resistance protein (transport); major facilitator transporter complement(4568556..4569821) Escherichia coli ATCC 8739 6066287 YP_001727067.1 CDS EcolC_4143 NC_010468.1 4569923 4570903 R PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sfx:S3803 hypothetical protein; xylose isomerase domain-containing protein complement(4569923..4570903) Escherichia coli ATCC 8739 6066295 YP_001727068.1 CDS EcolC_4144 NC_010468.1 4570911 4571621 R PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: sfv:SFV_3628 putative transcriptional regulator; GntR family transcriptional regulator complement(4570911..4571621) Escherichia coli ATCC 8739 6066302 YP_001727069.1 CDS EcolC_4145 NC_010468.1 4571838 4573661 R TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: sdy:SDY_3872 putative GTP-binding factor; GTP-binding protein complement(4571838..4573661) Escherichia coli ATCC 8739 6066308 YP_001727070.1 CDS glnA NC_010468.1 4574034 4575443 D forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4574034..4575443 Escherichia coli ATCC 8739 6066327 YP_001727071.1 CDS glnL NC_010468.1 4575729 4576778 D sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4575729..4576778 Escherichia coli ATCC 8739 6066346 YP_001727072.1 CDS glnG NC_010468.1 4576790 4578199 D response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4576790..4578199 Escherichia coli ATCC 8739 6066358 YP_001727073.1 CDS EcolC_4149 NC_010468.1 4578611 4579984 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(4578611..4579984) Escherichia coli ATCC 8739 6066365 YP_001727074.1 CDS EcolC_4150 NC_010468.1 4580173 4580679 R PFAM: protein of unknown function DUF414; KEGG: sdy:SDY_3877 hypothetical protein; hypothetical protein complement(4580173..4580679) Escherichia coli ATCC 8739 6066371 YP_001727075.1 CDS engB NC_010468.1 4581261 4581893 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4581261..4581893 Escherichia coli ATCC 8739 6066397 YP_001727076.1 CDS EcolC_4152 NC_010468.1 4582275 4585061 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(4582275..4585061) Escherichia coli ATCC 8739 6066521 YP_001727077.1 CDS EcolC_4153 NC_010468.1 4585425 4586357 D PFAM: phospholipid/glycerol acyltransferase; KEGG: ssn:SSON_4035 putative endonuclease; putative acyltransferase 4585425..4586357 Escherichia coli ATCC 8739 6066543 YP_001727078.1 CDS EcolC_4154 NC_010468.1 4586398 4587828 R PFAM: protein of unknown function DUF945; KEGG: sfx:S3815 putative GTP-binding protein; hypothetical protein complement(4586398..4587828) Escherichia coli ATCC 8739 6066576 YP_001727079.1 CDS EcolC_4155 NC_010468.1 4587983 4588609 R PFAM: DSBA oxidoreductase; KEGG: sbo:SBO_3872 protein disulfide isomerase I; protein disulfide isomerase I complement(4587983..4588609) Escherichia coli ATCC 8739 6066594 YP_001727080.1 CDS EcolC_4156 NC_010468.1 4588626 4589612 R catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase complement(4588626..4589612) Escherichia coli ATCC 8739 6066606 YP_001727081.1 CDS EcolC_4157 NC_010468.1 4589689 4589958 R PFAM: protein of unknown function DUF1040; KEGG: sdy:SDY_3887 hypothetical protein; hypothetical protein complement(4589689..4589958) Escherichia coli ATCC 8739 6066668 YP_001727082.1 CDS mobA NC_010468.1 4590028 4590612 D in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4590028..4590612 Escherichia coli ATCC 8739 6066689 YP_001727083.1 CDS EcolC_4159 NC_010468.1 4590594 4591121 D in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4590594..4591121 Escherichia coli ATCC 8739 6066708 YP_001727084.1 CDS hemG NC_010468.1 4596703 4597248 R catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase complement(4596703..4597248) Escherichia coli ATCC 8739 6066981 YP_001727085.1 CDS EcolC_4161 NC_010468.1 4597260 4598711 R TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: sdy:SDY_3896 potassium uptake protein; potassium transporter complement(4597260..4598711) Escherichia coli ATCC 8739 6067037 YP_001727086.1 CDS EcolC_4162 NC_010468.1 4598750 4599367 R PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: sdy:SDY_3897 hypothetical protein; hypothetical protein complement(4598750..4599367) Escherichia coli ATCC 8739 6067045 YP_001727087.1 CDS EcolC_4163 NC_010468.1 4599364 4600695 R catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase complement(4599364..4600695) Escherichia coli ATCC 8739 6067067 YP_001727088.1 CDS fadB NC_010468.1 4600885 4603074 D includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4600885..4603074 Escherichia coli ATCC 8739 6067071 YP_001727089.1 CDS fadA NC_010468.1 4603084 4604247 D FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4603084..4604247 Escherichia coli ATCC 8739 6067123 YP_001727090.1 CDS fre NC_010468.1 4604431 4605132 R NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase complement(4604431..4605132) Escherichia coli ATCC 8739 6067132 YP_001727091.1 CDS EcolC_4167 NC_010468.1 4605178 4606671 R catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(4605178..4606671) Escherichia coli ATCC 8739 6067168 YP_001727092.1 CDS rfaH NC_010468.1 4606838 4607326 D TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; KEGG: sdy:SDY_3903 transcriptional activator affecting biosynthesis of lipopolysaccharide core, F pilin, and haemolysin; transcriptional activator RfaH 4606838..4607326 Escherichia coli ATCC 8739 6067170 YP_001727093.1 CDS EcolC_4169 NC_010468.1 4607323 4608105 R magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD complement(4607323..4608105) Escherichia coli ATCC 8739 6067207 YP_001727094.1 CDS EcolC_4170 NC_010468.1 4608147 4608923 R with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC complement(4608147..4608923) Escherichia coli ATCC 8739 6067234 YP_001727095.1 CDS EcolC_4171 NC_010468.1 4608926 4609441 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(4608926..4609441) Escherichia coli ATCC 8739 6067245 YP_001727096.1 CDS tatA NC_010468.1 4609445 4609714 R TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A complement(4609445..4609714) Escherichia coli ATCC 8739 6067249 YP_001727097.1 CDS ubiB NC_010468.1 4609793 4611433 R an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB complement(4609793..4611433) Escherichia coli ATCC 8739 6067256 YP_001727098.1 CDS EcolC_4174 NC_010468.1 4611430 4612035 R PFAM: Sterol-binding domain protein; KEGG: sbo:SBO_3848 hypothetical protein; sterol-binding domain-containing protein complement(4611430..4612035) Escherichia coli ATCC 8739 6067258 YP_001727099.1 CDS ubiE NC_010468.1 4612049 4612804 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(4612049..4612804) Escherichia coli ATCC 8739 6067259 YP_001727100.1 CDS EcolC_4176 NC_010468.1 4612899 4614326 R YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC complement(4612899..4614326) Escherichia coli ATCC 8739 6067265 YP_001727101.1 CDS EcolC_4177 NC_010468.1 4614467 4615228 R catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase complement(4614467..4615228) Escherichia coli ATCC 8739 6067267 YP_001727102.1 CDS EcolC_4178 NC_010468.1 4615491 4616306 D PFAM: dienelactone hydrolase; KEGG: sfl:SF3908 carboxymethylenebutenolidase; carboxymethylenebutenolidase 4615491..4616306 Escherichia coli ATCC 8739 6067276 YP_001727103.1 CDS EcolC_4179 NC_010468.1 4616346 4618607 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(4616346..4618607) Escherichia coli ATCC 8739 6067326 YP_001727104.1 CDS EcolC_4180 NC_010468.1 4618725 4619678 D PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbo:SBO_3840 MetR; LysR family transcriptional regulator 4618725..4619678 Escherichia coli ATCC 8739 6067345 YP_001727105.1 CDS EcolC_4181 NC_010468.1 4619566 4620465 R TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4001 hypothetical protein; carboxylate/amino acid/amine transporter complement(4619566..4620465) Escherichia coli ATCC 8739 6067347 YP_001727106.1 CDS EcolC_4182 NC_010468.1 4620541 4621341 R purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase complement(4620541..4621341) Escherichia coli ATCC 8739 6067364 YP_001727107.1 CDS EcolC_4183 NC_010468.1 4621349 4622371 R lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 complement(4621349..4622371) Escherichia coli ATCC 8739 6067418 YP_001727108.1 CDS rhtB NC_010468.1 4622482 4623102 D TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3674 hypothetical protein; homoserine/homoserine lactone efflux protein 4622482..4623102 Escherichia coli ATCC 8739 6067426 YP_001727109.1 CDS EcolC_4185 NC_010468.1 4623164 4623784 R TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3675 hypothetical protein; threonine efflux system complement(4623164..4623784) Escherichia coli ATCC 8739 6067430 YP_001727110.1 CDS EcolC_4186 NC_010468.1 4623848 4625677 R functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ complement(4623848..4625677) Escherichia coli ATCC 8739 6067433 YP_001727111.1 CDS EcolC_4187 NC_010468.1 4625810 4626679 R catalyzes the hydrolysis of phosphatidylcholine; phospholipase A complement(4625810..4626679) Escherichia coli ATCC 8739 6067449 YP_001727112.1 CDS EcolC_4188 NC_010468.1 4626844 4627311 D PFAM: thioesterase superfamily protein; KEGG: ssn:SSON_3994 hypothetical protein; hypothetical protein 4626844..4627311 Escherichia coli ATCC 8739 6067456 YP_001727113.1 CDS EcolC_4189 NC_010468.1 4627363 4628253 D TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfv:SFV_3679 hypothetical protein; transporter DMT superfamily protein 4627363..4628253 Escherichia coli ATCC 8739 6067462 YP_001727114.1 CDS EcolC_4190 NC_010468.1 4628348 4628728 D KEGG: sfx:S3859 hypothetical protein; hypothetical protein 4628348..4628728 Escherichia coli ATCC 8739 6067479 YP_001727115.1 CDS EcolC_4191 NC_010468.1 4628742 4629122 D KEGG: sfv:SFV_3681 hypothetical protein; hypothetical protein 4628742..4629122 Escherichia coli ATCC 8739 6067502 YP_001727116.1 CDS EcolC_4192 NC_010468.1 4629165 4630115 R responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA complement(4629165..4630115) Escherichia coli ATCC 8739 6067503 YP_001727117.1 CDS EcolC_4193 NC_010468.1 4630485 4631249 D KEGG: sdy:SDY_3930 predicted periplasmic protein; hypothetical protein 4630485..4631249 Escherichia coli ATCC 8739 6067513 YP_001727118.1 CDS uvrD NC_010468.1 4631396 4633558 R unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II complement(4631396..4633558) Escherichia coli ATCC 8739 6067516 YP_001727119.1 CDS EcolC_4195 NC_010468.1 4633642 4634358 R YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase complement(4633642..4634358) Escherichia coli ATCC 8739 6067538 YP_001727120.1 CDS xerC NC_010468.1 4634358 4635254 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(4634358..4635254) Escherichia coli ATCC 8739 6067551 YP_001727121.1 CDS EcolC_4197 NC_010468.1 4635251 4635958 R PFAM: protein of unknown function DUF484; KEGG: sbo:SBO_3821 hypothetical protein; hypothetical protein complement(4635251..4635958) Escherichia coli ATCC 8739 6067552 YP_001727122.1 CDS dapF NC_010468.1 4635955 4636779 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(4635955..4636779) Escherichia coli ATCC 8739 6067553 YP_001727123.1 CDS EcolC_4199 NC_010468.1 4636816 4637019 R KEGG: ssn:SSON_3981 hypothetical protein; hypothetical protein complement(4636816..4637019) Escherichia coli ATCC 8739 6067578 YP_001727124.1 CDS cyaY NC_010468.1 4637482 4637802 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4637482..4637802 Escherichia coli ATCC 8739 6067589 YP_001727125.1 CDS cyaA NC_010468.1 4637842 4640388 R catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase complement(4637842..4640388) Escherichia coli ATCC 8739 6067657 YP_001727126.1 CDS hemC NC_010468.1 4640754 4641716 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4640754..4641716 Escherichia coli ATCC 8739 6067671 YP_001727127.1 CDS hemD NC_010468.1 4641713 4642453 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4641713..4642453 Escherichia coli ATCC 8739 6067687 YP_001727128.1 CDS EcolC_4204 NC_010468.1 4642475 4643668 D PFAM: protein of unknown function DUF513 hemX; KEGG: sfx:S3881 uroporphyrinogen III methylase; putative uroporphyrinogen III C-methyltransferase 4642475..4643668 Escherichia coli ATCC 8739 6067694 YP_001727129.1 CDS EcolC_4205 NC_010468.1 4643671 4644867 D TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: sbo:SBO_3813 HemY; putative protoheme IX biogenesis protein 4643671..4644867 Escherichia coli ATCC 8739 6067700 YP_001727130.1 CDS EcolC_4206 NC_010468.1 4645791 4647026 R PFAM: Radical SAM domain protein; KEGG: sfv:SFV_3703 putative arylsulfatase regulator; radical SAM domain-containing protein complement(4645791..4647026) Escherichia coli ATCC 8739 6067713 YP_001727131.1 CDS EcolC_4207 NC_010468.1 4647712 4649097 R uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK complement(4647712..4649097) Escherichia coli ATCC 8739 6067731 YP_001727132.1 CDS EcolC_4208 NC_010468.1 4649288 4650028 R TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: sdy:SDY_3953 probable UDP-N-acetyl-D-mannosaminuronic acid transferase; putative UDP-N-acetyl-D-mannosaminuronic acid transferase complement(4649288..4650028) Escherichia coli ATCC 8739 6067745 YP_001727133.1 CDS EcolC_4209 NC_010468.1 4650031 4651383 R enterobacterial common antigen polymerase; putative common antigen polymerase complement(4650031..4651383) Escherichia coli ATCC 8739 6067749 YP_001727134.1 CDS EcolC_4210 NC_010468.1 4651380 4652459 R catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase complement(4651380..4652459) Escherichia coli ATCC 8739 6067755 YP_001727135.1 CDS EcolC_4211 NC_010468.1 4652456 4653706 R PFAM: polysaccharide biosynthesis protein; KEGG: sbo:SBO_3803 putative cytochrome; polysaccharide biosynthesis protein complement(4652456..4653706) Escherichia coli ATCC 8739 6067756 YP_001727136.1 CDS EcolC_4212 NC_010468.1 4653708 4654838 R catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase complement(4653708..4654838) Escherichia coli ATCC 8739 6067760 YP_001727137.1 CDS EcolC_4213 NC_010468.1 4654843 4655517 R TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_3714 hypothetical protein; TDP-fucosamine acetyltransferase complement(4654843..4655517) Escherichia coli ATCC 8739 6067774 YP_001727138.1 CDS EcolC_4214 NC_010468.1 4655495 4656376 R TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfv:SFV_3715 glucose-1-phosphate thymidylyltransferase; glucose-1-phosphate thymidylyltransferase complement(4655495..4656376) Escherichia coli ATCC 8739 6067780 YP_001727139.1 CDS EcolC_4215 NC_010468.1 4656395 4657462 R TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ssn:SSON_3960 dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase complement(4656395..4657462) Escherichia coli ATCC 8739 6067781 YP_001727140.1 CDS wecC NC_010468.1 4657462 4658724 R catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase complement(4657462..4658724) Escherichia coli ATCC 8739 6067782 YP_001727141.1 CDS EcolC_4217 NC_010468.1 4658721 4659851 R PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: sdy:SDY_3962 UDP-N-acetyl glucosamine -2-epimerase; UDP-N-acetylglucosamine 2-epimerase complement(4658721..4659851) Escherichia coli ATCC 8739 6067787 YP_001727142.1 CDS EcolC_4218 NC_010468.1 4659907 4660953 R Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE complement(4659907..4660953) Escherichia coli ATCC 8739 6067792 YP_001727143.1 CDS EcolC_4219 NC_010468.1 4660965 4662068 R TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: ssn:SSON_3956 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase complement(4660965..4662068) Escherichia coli ATCC 8739 6067801 YP_001727144.1 CDS rho NC_010468.1 4662308 4663567 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(4662308..4663567) Escherichia coli ATCC 8739 6067806 YP_001727145.1 CDS EcolC_4221 NC_010468.1 4663652 4663753 R KEGG: sdy:SDY_3967 rho operon leader peptide; putative rho operon leader peptide complement(4663652..4663753) Escherichia coli ATCC 8739 6067807 YP_001727146.1 CDS trxA NC_010468.1 4663894 4664223 R TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cko:CKO_00123 hypothetical protein; thioredoxin complement(4663894..4664223) Escherichia coli ATCC 8739 6067813 YP_001727147.1 CDS EcolC_4223 NC_010468.1 4664354 4665619 D enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4664354..4665619 Escherichia coli ATCC 8739 6067816 YP_001727148.1 CDS EcolC_4224 NC_010468.1 4665755 4667239 D catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4665755..4667239 Escherichia coli ATCC 8739 6067819 YP_001727149.1 CDS EcolC_4225 NC_010468.1 4667286 4669307 R single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep complement(4667286..4669307) Escherichia coli ATCC 8739 6067822 YP_001727150.1 CDS EcolC_4227 NC_010468.1 4670171 4670452 D PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cko:CKO_00116 hypothetical protein; PpiC-type peptidyl-prolyl cis-trans isomerase 4670171..4670452 Escherichia coli ATCC 8739 6067828 YP_001727151.1 CDS EcolC_4228 NC_010468.1 4670539 4672014 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(4670539..4672014) Escherichia coli ATCC 8739 6067837 YP_001727152.1 CDS EcolC_4229 NC_010468.1 4672164 4673057 D participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4672164..4673057 Escherichia coli ATCC 8739 6067840 YP_001727153.1 CDS EcolC_4230 NC_010468.1 4673109 4674656 R threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase complement(4673109..4674656) Escherichia coli ATCC 8739 6067843 YP_001727154.1 CDS EcolC_4231 NC_010468.1 4674656 4676506 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(4674656..4676506) Escherichia coli ATCC 8739 6067855 YP_001727155.1 CDS EcolC_4232 NC_010468.1 4676571 4677500 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(4676571..4677500) Escherichia coli ATCC 8739 6067857 YP_001727156.1 CDS ilvM NC_010468.1 4677520 4677783 R KEGG: sdy:SDY_3979 acetolactate synthase II, valine insensitive, small subunit; acetolactate synthase 2 regulatory subunit complement(4677520..4677783) Escherichia coli ATCC 8739 6067861 YP_001727157.1 CDS EcolC_4234 NC_010468.1 4677780 4679426 R catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit complement(4677780..4679426) Escherichia coli ATCC 8739 6067862 YP_001727158.1 CDS EcolC_4235 NC_010468.1 4679566 4679664 R PFAM: IlvGEDA operon leader peptide; KEGG: sdy:SDY_3981 ilvGMEDA operon leader peptide; ilvG operon leader peptide complement(4679566..4679664) Escherichia coli ATCC 8739 6067864 YP_001727159.1 CDS EcolC_4236 NC_010468.1 4680017 4681537 D among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease 4680017..4681537 Escherichia coli ATCC 8739 6067869 YP_001727160.1 CDS EcolC_4237 NC_010468.1 4681562 4681900 R PFAM: protein of unknown function DUF413; KEGG: sdy:SDY_3984 hypothetical protein; hypothetical protein complement(4681562..4681900) Escherichia coli ATCC 8739 6067870 YP_001727161.1 CDS EcolC_4238 NC_010468.1 4682019 4682858 D Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4682019..4682858 Escherichia coli ATCC 8739 6067872 YP_001727162.1 CDS EcolC_4239 NC_010468.1 4688661 4689353 D PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: sfv:SFV_3744 hypothetical protein; GntR family transcriptional regulator 4688661..4689353 Escherichia coli ATCC 8739 6067916 YP_001727163.1 CDS EcolC_4240 NC_010468.1 4689376 4690803 D TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_3993 putative transport protein; EmrB/QacA family drug resistance transporter 4689376..4690803 Escherichia coli ATCC 8739 6067919 YP_001727164.1 CDS EcolC_4241 NC_010468.1 4690769 4691761 R DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR complement(4690769..4691761) Escherichia coli ATCC 8739 6067932 YP_001727165.1 CDS EcolC_4242 NC_010468.1 4691765 4692694 R catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase complement(4691765..4692694) Escherichia coli ATCC 8739 6067934 YP_001727166.1 CDS EcolC_4243 NC_010468.1 4692820 4693710 R periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB complement(4692820..4693710) Escherichia coli ATCC 8739 6067935 YP_001727167.1 CDS rbsC NC_010468.1 4693735 4694700 R functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease complement(4693735..4694700) Escherichia coli ATCC 8739 6067943 YP_001727168.1 CDS EcolC_4245 NC_010468.1 4694705 4696210 R with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein complement(4694705..4696210) Escherichia coli ATCC 8739 6067948 YP_001727169.1 CDS EcolC_4246 NC_010468.1 4696218 4696637 R cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase complement(4696218..4696637) Escherichia coli ATCC 8739 6067956 YP_001727170.1 CDS trkD NC_010468.1 4696804 4698672 R Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup complement(4696804..4698672) Escherichia coli ATCC 8739 6067959 YP_001727171.1 CDS EcolC_4248 NC_010468.1 4698895 4700391 D interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4698895..4700391 Escherichia coli ATCC 8739 6067960 YP_001727172.1 CDS yieM NC_010468.1 4700385 4701836 D contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4700385..4701836 Escherichia coli ATCC 8739 6067963 YP_001727173.1 CDS EcolC_4250 NC_010468.1 4701841 4702833 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(4701841..4702833) Escherichia coli ATCC 8739 6067966 YP_001727174.1 CDS EcolC_4251 NC_010468.1 4702985 4703443 D transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4702985..4703443 Escherichia coli ATCC 8739 6067974 YP_001727175.1 CDS EcolC_4252 NC_010468.1 4703533 4703976 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4703533..4703976 Escherichia coli ATCC 8739 6067976 YP_001727176.1 CDS EcolC_4253 NC_010468.1 4704355 4706244 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4704355..4706244 Escherichia coli ATCC 8739 6067980 YP_001727177.1 CDS gidB NC_010468.1 4706308 4706931 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4706308..4706931 Escherichia coli ATCC 8739 6067982 YP_001727178.1 CDS EcolC_4255 NC_010468.1 4707548 4707928 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4707548..4707928 Escherichia coli ATCC 8739 6067983 YP_001727179.1 CDS EcolC_4256 NC_010468.1 4707937 4708752 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4707937..4708752 Escherichia coli ATCC 8739 6067984 YP_001727180.1 CDS EcolC_4257 NC_010468.1 4708799 4709038 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 4708799..4709038 Escherichia coli ATCC 8739 6067986 YP_001727181.1 CDS EcolC_4258 NC_010468.1 4709100 4709570 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 4709100..4709570 Escherichia coli ATCC 8739 6067998 YP_001727182.1 CDS EcolC_4259 NC_010468.1 4709585 4710118 D Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4709585..4710118 Escherichia coli ATCC 8739 6068001 YP_001727183.1 CDS EcolC_4260 NC_010468.1 4710131 4711672 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 4710131..4711672 Escherichia coli ATCC 8739 6068003 YP_001727184.1 CDS EcolC_4261 NC_010468.1 4711723 4712586 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4711723..4712586 Escherichia coli ATCC 8739 6068010 YP_001727185.1 CDS EcolC_4262 NC_010468.1 4712613 4713995 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4712613..4713995 Escherichia coli ATCC 8739 6068011 YP_001727186.1 CDS atpC NC_010468.1 4714016 4714435 D part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 4714016..4714435 Escherichia coli ATCC 8739 6068013 YP_001727187.1 CDS glmU NC_010468.1 4714788 4716158 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4714788..4716158 Escherichia coli ATCC 8739 6068016 YP_001727188.1 CDS EcolC_4265 NC_010468.1 4716320 4718149 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4716320..4718149 Escherichia coli ATCC 8739 6068019 YP_001727189.1 CDS EcolC_4266 NC_010468.1 4718463 4719503 D TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sbo:SBO_3654 high-affinity phosphate-specific transport system periplasmic phosphate-binding protein; phosphate ABC transporter substrate-binding protein 4718463..4719503 Escherichia coli ATCC 8739 6068031 YP_001727190.1 CDS pstC NC_010468.1 4719589 4720548 D part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease PstC 4719589..4720548 Escherichia coli ATCC 8739 6068032 YP_001727191.1 CDS pstA NC_010468.1 4720548 4721438 D Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease PtsA 4720548..4721438 Escherichia coli ATCC 8739 6068035 YP_001727192.1 CDS pstB NC_010468.1 4721621 4722394 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4721621..4722394 Escherichia coli ATCC 8739 6068045 YP_001727193.1 CDS EcolC_4270 NC_010468.1 4722409 4723134 D regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4722409..4723134 Escherichia coli ATCC 8739 6068049 YP_001727194.1 CDS EcolC_4271 NC_010468.1 4723420 4724256 D positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4723420..4724256 Escherichia coli ATCC 8739 6068058 YP_001727195.1 CDS EcolC_4272 NC_010468.1 4724389 4726266 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 4724389..4726266 Escherichia coli ATCC 8739 6068067 YP_001727196.1 CDS EcolC_4273 NC_010468.1 4726285 4727697 D PFAM: glycoside hydrolase family 1; KEGG: sfv:SFV_3786 phospho-beta-glucosidase B; cryptic; glycoside hydrolase family protein 4726285..4727697 Escherichia coli ATCC 8739 6068073 YP_001727197.1 CDS EcolC_4274 NC_010468.1 4727766 4729382 D PFAM: porin LamB type; KEGG: ssn:SSON_3915 putative receptor protein; LamB type porin 4727766..4729382 Escherichia coli ATCC 8739 6068077 YP_001727198.1 CDS EcolC_4275 NC_010468.1 4729409 4730578 D PFAM: putative esterase; glycoside hydrolase family 13 domain protein; KEGG: sfx:S4034 putative xylanase; glycoside hydrolase family protein 4729409..4730578 Escherichia coli ATCC 8739 6068079 YP_001727199.1 CDS EcolC_4276 NC_010468.1 4730593 4731315 D PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfv:SFV_3789 putative isomerase; putative 6-phosphogluconolactonase 4730593..4731315 Escherichia coli ATCC 8739 6068089 YP_001727200.1 CDS EcolC_4277 NC_010468.1 4731377 4731964 R PFAM: protein of unknown function UPF0167; KEGG: sfv:SFV_3790 hypothetical protein; hypothetical protein complement(4731377..4731964) Escherichia coli ATCC 8739 6068093 YP_001727201.1 CDS EcolC_4278 NC_010468.1 4732013 4732486 R might be involved in hypersensitivity to nitrofurzone; putative inner membrane protein complement(4732013..4732486) Escherichia coli ATCC 8739 6068095 YP_001727202.1 CDS EcolC_4279 NC_010468.1 4732553 4733218 R YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase complement(4732553..4733218) Escherichia coli ATCC 8739 6068097 YP_001727203.1 CDS EcolC_4280 NC_010468.1 4733385 4734722 D PFAM: Xanthine/uracil/vitamin C permease; KEGG: sdy:SDY_4199 putative membrane/transport protein; xanthine/uracil/vitamin C permease 4733385..4734722 Escherichia coli ATCC 8739 6068105 YP_001727204.1 CDS EcolC_4281 NC_010468.1 4734776 4735342 R PFAM: NADPH-dependent FMN reductase; KEGG: sfv:SFV_3798 hypothetical protein; NADPH-dependent FMN reductase complement(4734776..4735342) Escherichia coli ATCC 8739 6068106 YP_001727205.1 CDS EcolC_4282 NC_010468.1 4735364 4736113 R KEGG: sbo:SBO_3663 hypothetical protein; hypothetical protein complement(4735364..4736113) Escherichia coli ATCC 8739 6068108 YP_001727206.1 CDS EcolC_4283 NC_010468.1 4736270 4737229 R Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ complement(4736270..4737229) Escherichia coli ATCC 8739 6068109 YP_001727207.1 CDS EcolC_4284 NC_010468.1 4737204 4738379 R Confers resistance to chloramphenicol; multidrug efflux system protein MdtL complement(4737204..4738379) Escherichia coli ATCC 8739 6068111 YP_001727208.1 CDS EcolC_4285 NC_010468.1 4738512 4739759 R tryptophan transporter of low affinity; tryptophan permease TnaB complement(4738512..4739759) Escherichia coli ATCC 8739 6068112 YP_001727209.1 CDS tnaA NC_010468.1 4739850 4741265 R tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase complement(4739850..4741265) Escherichia coli ATCC 8739 6068115 YP_001727210.1 CDS EcolC_4287 NC_010468.1 4741486 4741560 R TIGRFAM: tryptophanase leader peptide; PFAM: tryptophanese operon leader peptide; KEGG: sfx:S4016 tryptophanase leader peptide; tryptophanase leader peptide complement(4741486..4741560) Escherichia coli ATCC 8739 6068119 YP_001727211.1 CDS trmE NC_010468.1 4741803 4743167 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(4741803..4743167) Escherichia coli ATCC 8739 6068121 YP_001727212.1 CDS EcolC_4289 NC_010468.1 4743273 4744919 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC complement(4743273..4744919) Escherichia coli ATCC 8739 6068124 YP_001727213.1 CDS EcolC_4290 NC_010468.1 4744922 4745179 R PFAM: protein of unknown function DUF37; KEGG: sdy:SDY_4187 hypothetical protein; hypothetical protein complement(4744922..4745179) Escherichia coli ATCC 8739 6068126 YP_001727214.1 CDS rnpA NC_010468.1 4745143 4745469 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(4745143..4745469) Escherichia coli ATCC 8739 6068127 YP_001727215.1 CDS rpmH NC_010468.1 4745519 4745659 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(4745519..4745659) Escherichia coli ATCC 8739 6068132 EcolC_R0001 tRNA EcolC_R0001 NC_010468.1 55461 55551 R tRNA-Sec complement(55461..55551) Escherichia coli ATCC 8739 6068460 EcolC_R0002 tRNA EcolC_R0002 NC_010468.1 185962 186038 D tRNA-Pro 185962..186038 Escherichia coli ATCC 8739 6068248 EcolC_R0006 tRNA EcolC_R0006 NC_010468.1 467778 467854 D tRNA-Ile 467778..467854 Escherichia coli ATCC 8739 6067754 EcolC_R0007 tRNA EcolC_R0007 NC_010468.1 467897 467972 D tRNA-Ala 467897..467972 Escherichia coli ATCC 8739 6067768 EcolC_R0010 tRNA EcolC_R0010 NC_010468.1 471286 471361 D tRNA-Thr 471286..471361 Escherichia coli ATCC 8739 6067800 EcolC_R0012 tRNA EcolC_R0012 NC_010468.1 566202 566288 D tRNA-Leu 566202..566288 Escherichia coli ATCC 8739 6064491 EcolC_R0013 tRNA EcolC_R0013 NC_010468.1 570071 570147 D tRNA-Met 570071..570147 Escherichia coli ATCC 8739 6064605 EcolC_R0015 tRNA EcolC_R0015 NC_010468.1 680236 680311 R tRNA-Met complement(680236..680311) Escherichia coli ATCC 8739 6064699 EcolC_R0016 tRNA EcolC_R0016 NC_010468.1 802291 802366 R tRNA-Phe complement(802291..802366) Escherichia coli ATCC 8739 6066433 EcolC_R0018 tRNA EcolC_R0018 NC_010468.1 913686 913759 D tRNA-Gly 913686..913759 Escherichia coli ATCC 8739 6064651 EcolC_R0019 tRNA EcolC_R0019 NC_010468.1 973022 973098 R tRNA-Met complement(973022..973098) Escherichia coli ATCC 8739 6064508 EcolC_R0020 tRNA EcolC_R0020 NC_010468.1 973132 973208 R tRNA-Met complement(973132..973208) Escherichia coli ATCC 8739 6064487 EcolC_R0021 tRNA EcolC_R0021 NC_010468.1 973242 973318 R tRNA-Met complement(973242..973318) Escherichia coli ATCC 8739 6068737 EcolC_R0024 tRNA EcolC_R0024 NC_010468.1 1105418 1105510 D tRNA-Ser 1105418..1105510 Escherichia coli ATCC 8739 6067307 EcolC_R0025 tRNA EcolC_R0025 NC_010468.1 1105514 1105590 D tRNA-Arg 1105514..1105590 Escherichia coli ATCC 8739 6067248 EcolC_R0026 tRNA EcolC_R0026 NC_010468.1 1105789 1105865 D tRNA-Arg 1105789..1105865 Escherichia coli ATCC 8739 6067204 EcolC_R0027 tRNA EcolC_R0027 NC_010468.1 1105928 1106004 D tRNA-Arg 1105928..1106004 Escherichia coli ATCC 8739 6067173 EcolC_R0028 tRNA EcolC_R0028 NC_010468.1 1106203 1106279 D tRNA-Arg 1106203..1106279 Escherichia coli ATCC 8739 6067113 EcolC_R0029 tRNA EcolC_R0029 NC_010468.1 1138333 1138408 D tRNA-Met 1138333..1138408 Escherichia coli ATCC 8739 6066369 EcolC_R0032 tRNA EcolC_R0032 NC_010468.1 1183469 1183544 D tRNA-Glu 1183469..1183544 Escherichia coli ATCC 8739 6065238 EcolC_R0036 tRNA EcolC_R0036 NC_010468.1 1389757 1389832 R tRNA-Lys complement(1389757..1389832) Escherichia coli ATCC 8739 6064982 EcolC_R0037 tRNA EcolC_R0037 NC_010468.1 1389837 1389912 R tRNA-Val complement(1389837..1389912) Escherichia coli ATCC 8739 6066375 EcolC_R0038 tRNA EcolC_R0038 NC_010468.1 1389959 1390034 R tRNA-Val complement(1389959..1390034) Escherichia coli ATCC 8739 6064593 EcolC_R0039 tRNA EcolC_R0039 NC_010468.1 1390079 1390154 R tRNA-Val complement(1390079..1390154) Escherichia coli ATCC 8739 6064577 EcolC_R0040 tRNA EcolC_R0040 NC_010468.1 1392854 1392929 D tRNA-Ala 1392854..1392929 Escherichia coli ATCC 8739 6068074 EcolC_R0041 tRNA EcolC_R0041 NC_010468.1 1392969 1393044 D tRNA-Ala 1392969..1393044 Escherichia coli ATCC 8739 6065982 EcolC_R0042 tRNA EcolC_R0042 NC_010468.1 1434485 1434559 R tRNA-Arg complement(1434485..1434559) Escherichia coli ATCC 8739 6068541 EcolC_R0043 tRNA EcolC_R0043 NC_010468.1 1608887 1608963 R tRNA-Pro complement(1608887..1608963) Escherichia coli ATCC 8739 6067306 EcolC_R0044 tRNA EcolC_R0044 NC_010468.1 1846006 1846081 R tRNA-Asn complement(1846006..1846081) Escherichia coli ATCC 8739 6066991 EcolC_R0045 tRNA EcolC_R0045 NC_010468.1 1848415 1848490 R tRNA-Asn complement(1848415..1848490) Escherichia coli ATCC 8739 6064926 EcolC_R0046 tRNA EcolC_R0046 NC_010468.1 1850239 1850314 D tRNA-Asn 1850239..1850314 Escherichia coli ATCC 8739 6065443 EcolC_R0047 tRNA EcolC_R0047 NC_010468.1 1872545 1872620 R tRNA-Asn complement(1872545..1872620) Escherichia coli ATCC 8739 6065682 EcolC_R0048 tRNA EcolC_R0048 NC_010468.1 1873612 1873701 D tRNA-Ser 1873612..1873701 Escherichia coli ATCC 8739 6066082 EcolC_R0049 tRNA EcolC_R0049 NC_010468.1 1924574 1924649 D tRNA-Gly 1924574..1924649 Escherichia coli ATCC 8739 6067148 EcolC_R0050 tRNA EcolC_R0050 NC_010468.1 1924703 1924776 D tRNA-Cys 1924703..1924776 Escherichia coli ATCC 8739 6067140 EcolC_R0051 tRNA EcolC_R0051 NC_010468.1 1924789 1924875 D tRNA-Leu 1924789..1924875 Escherichia coli ATCC 8739 6067111 EcolC_R0053 tRNA EcolC_R0053 NC_010468.1 2170099 2170175 R tRNA-Val complement(2170099..2170175) Escherichia coli ATCC 8739 6068304 EcolC_R0054 tRNA EcolC_R0054 NC_010468.1 2170180 2170256 R tRNA-Val complement(2170180..2170256) Escherichia coli ATCC 8739 6068289 EcolC_R0056 tRNA EcolC_R0056 NC_010468.1 2637806 2637890 D tRNA-Tyr 2637806..2637890 Escherichia coli ATCC 8739 6066993 EcolC_R0058 tRNA EcolC_R0058 NC_010468.1 2638100 2638184 D tRNA-Tyr 2638100..2638184 Escherichia coli ATCC 8739 6066912 EcolC_R0064 tRNA EcolC_R0064 NC_010468.1 2812260 2812347 D tRNA-Ser 2812260..2812347 Escherichia coli ATCC 8739 6066792 EcolC_R0065 tRNA EcolC_R0065 NC_010468.1 2878648 2878735 D tRNA-Ser 2878648..2878735 Escherichia coli ATCC 8739 6065612 EcolC_R0066 tRNA EcolC_R0066 NC_010468.1 2984383 2984470 D tRNA-Ser 2984383..2984470 Escherichia coli ATCC 8739 6066700 EcolC_R0067 tRNA EcolC_R0067 NC_010468.1 3173760 3173835 R tRNA-Lys complement(3173760..3173835) Escherichia coli ATCC 8739 6065425 EcolC_R0068 tRNA EcolC_R0068 NC_010468.1 3173968 3174043 R tRNA-Lys complement(3173968..3174043) Escherichia coli ATCC 8739 6065431 EcolC_R0069 tRNA EcolC_R0069 NC_010468.1 3174190 3174265 R tRNA-Lys complement(3174190..3174265) Escherichia coli ATCC 8739 6065437 EcolC_R0070 tRNA EcolC_R0070 NC_010468.1 3174269 3174344 R tRNA-Val complement(3174269..3174344) Escherichia coli ATCC 8739 6065442 EcolC_R0071 tRNA EcolC_R0071 NC_010468.1 3174396 3174471 R tRNA-Lys complement(3174396..3174471) Escherichia coli ATCC 8739 6065445 EcolC_R0072 tRNA EcolC_R0072 NC_010468.1 3174474 3174549 R tRNA-Val complement(3174474..3174549) Escherichia coli ATCC 8739 6065452 EcolC_R0073 tRNA EcolC_R0073 NC_010468.1 3174685 3174760 R tRNA-Lys complement(3174685..3174760) Escherichia coli ATCC 8739 6066458 EcolC_R0074 tRNA EcolC_R0074 NC_010468.1 3259238 3259314 D tRNA-Met 3259238..3259314 Escherichia coli ATCC 8739 6065772 EcolC_R0075 tRNA EcolC_R0075 NC_010468.1 3259323 3259407 D tRNA-Leu 3259323..3259407 Escherichia coli ATCC 8739 6065783 EcolC_R0076 tRNA EcolC_R0076 NC_010468.1 3259431 3259505 D tRNA-Gln 3259431..3259505 Escherichia coli ATCC 8739 6065794 EcolC_R0077 tRNA EcolC_R0077 NC_010468.1 3259540 3259614 D tRNA-Gln 3259540..3259614 Escherichia coli ATCC 8739 6064897 EcolC_R0078 tRNA EcolC_R0078 NC_010468.1 3259630 3259706 D tRNA-Met 3259630..3259706 Escherichia coli ATCC 8739 6065808 EcolC_R0079 tRNA EcolC_R0079 NC_010468.1 3259754 3259828 D tRNA-Gln 3259754..3259828 Escherichia coli ATCC 8739 6065825 EcolC_R0080 tRNA EcolC_R0080 NC_010468.1 3259866 3259940 D tRNA-Gln 3259866..3259940 Escherichia coli ATCC 8739 6065830 EcolC_R0081 tRNA EcolC_R0081 NC_010468.1 3381594 3381670 R tRNA-Arg complement(3381594..3381670) Escherichia coli ATCC 8739 6066226 EcolC_R0083 tRNA EcolC_R0083 NC_010468.1 3611627 3611707 R tRNA-OTHER complement(3611627..3611707) Escherichia coli ATCC 8739 6064738 EcolC_R0084 tRNA EcolC_R0084 NC_010468.1 3662257 3662332 R tRNA-Thr complement(3662257..3662332) Escherichia coli ATCC 8739 6066510 EcolC_R0085 tRNA EcolC_R0085 NC_010468.1 3762720 3762796 R tRNA-Asp complement(3762720..3762796) Escherichia coli ATCC 8739 6067955 EcolC_R0086 tRNA EcolC_R0086 NC_010468.1 3770723 3770799 R tRNA-Asp complement(3770723..3770799) Escherichia coli ATCC 8739 6068061 EcolC_R0089 tRNA EcolC_R0089 NC_010468.1 3774244 3774319 R tRNA-Ala complement(3774244..3774319) Escherichia coli ATCC 8739 6068114 EcolC_R0090 tRNA EcolC_R0090 NC_010468.1 3774362 3774438 R tRNA-Ile complement(3774362..3774438) Escherichia coli ATCC 8739 6068130 EcolC_R0094 tRNA EcolC_R0094 NC_010468.1 4036615 4036701 D tRNA-Leu 4036615..4036701 Escherichia coli ATCC 8739 6065164 EcolC_R0095 tRNA EcolC_R0095 NC_010468.1 4036730 4036816 D tRNA-Leu 4036730..4036816 Escherichia coli ATCC 8739 6065966 EcolC_R0096 tRNA EcolC_R0096 NC_010468.1 4036851 4036937 D tRNA-Leu 4036851..4036937 Escherichia coli ATCC 8739 6066523 EcolC_R0097 tRNA EcolC_R0097 NC_010468.1 4099232 4099316 R tRNA-Leu complement(4099232..4099316) Escherichia coli ATCC 8739 6068610 EcolC_R0098 tRNA EcolC_R0098 NC_010468.1 4204418 4204493 R tRNA-Gly complement(4204418..4204493) Escherichia coli ATCC 8739 6067183 EcolC_R0099 tRNA EcolC_R0099 NC_010468.1 4204529 4204604 R tRNA-Gly complement(4204529..4204604) Escherichia coli ATCC 8739 6067188 EcolC_R0100 tRNA EcolC_R0100 NC_010468.1 4204641 4204716 R tRNA-Gly complement(4204641..4204716) Escherichia coli ATCC 8739 6067282 EcolC_R0101 tRNA EcolC_R0101 NC_010468.1 4234448 4234523 D tRNA-Phe 4234448..4234523 Escherichia coli ATCC 8739 6068550 EcolC_R0104 tRNA EcolC_R0104 NC_010468.1 4423424 4423499 R tRNA-Glu complement(4423424..4423499) Escherichia coli ATCC 8739 6064581 EcolC_R0106 tRNA EcolC_R0106 NC_010468.1 4456500 4456575 R tRNA-Thr complement(4456500..4456575) Escherichia coli ATCC 8739 6064827 EcolC_R0107 tRNA EcolC_R0107 NC_010468.1 4456582 4456656 R tRNA-Gly complement(4456582..4456656) Escherichia coli ATCC 8739 6064828 EcolC_R0108 tRNA EcolC_R0108 NC_010468.1 4456773 4456857 R tRNA-Tyr complement(4456773..4456857) Escherichia coli ATCC 8739 6064891 EcolC_R0109 tRNA EcolC_R0109 NC_010468.1 4456866 4456941 R tRNA-Thr complement(4456866..4456941) Escherichia coli ATCC 8739 6064900 EcolC_R0112 tRNA EcolC_R0112 NC_010468.1 4463713 4463788 R tRNA-Glu complement(4463713..4463788) Escherichia coli ATCC 8739 6065060 EcolC_R0118 tRNA EcolC_R0118 NC_010468.1 4594521 4594596 R tRNA-Ala complement(4594521..4594596) Escherichia coli ATCC 8739 6066842 EcolC_R0119 tRNA EcolC_R0119 NC_010468.1 4594639 4594715 R tRNA-Ile complement(4594639..4594715) Escherichia coli ATCC 8739 6066885 EcolC_R0121 tRNA EcolC_R0121 NC_010468.1 4647173 4647249 R tRNA-Pro complement(4647173..4647249) Escherichia coli ATCC 8739 6067716 EcolC_R0122 tRNA EcolC_R0122 NC_010468.1 4647292 4647378 R tRNA-Leu complement(4647292..4647378) Escherichia coli ATCC 8739 6067717 EcolC_R0123 tRNA EcolC_R0123 NC_010468.1 4647399 4647474 R tRNA-His complement(4647399..4647474) Escherichia coli ATCC 8739 6067722 EcolC_R0124 tRNA EcolC_R0124 NC_010468.1 4647533 4647609 R tRNA-Arg complement(4647533..4647609) Escherichia coli ATCC 8739 6067729 EcolC_R0125 tRNA EcolC_R0125 NC_010468.1 4682954 4683029 R tRNA-Trp complement(4682954..4683029) Escherichia coli ATCC 8739 6067876 EcolC_R0126 tRNA EcolC_R0126 NC_010468.1 4683038 4683114 R tRNA-Asp complement(4683038..4683114) Escherichia coli ATCC 8739 6067880 EcolC_R0129 tRNA EcolC_R0129 NC_010468.1 4686478 4686553 R tRNA-Glu complement(4686478..4686553) Escherichia coli ATCC 8739 6067907 EcolC_R0005 rRNA EcolC_R0005 NC_010468.1 466175 467708 D 16S ribosomal RNA 466175..467708 Escherichia coli ATCC 8739 6067743 EcolC_R0008 rRNA EcolC_R0008 NC_010468.1 468076 471061 D 23S ribosomal RNA 468076..471061 Escherichia coli ATCC 8739 6067786 EcolC_R0009 rRNA EcolC_R0009 NC_010468.1 471158 471272 D 5S ribosomal RNA 471158..471272 Escherichia coli ATCC 8739 6067794 EcolC_R0011 rRNA EcolC_R0011 NC_010468.1 471403 471517 D 5S ribosomal RNA 471403..471517 Escherichia coli ATCC 8739 6067814 EcolC_R0017 rRNA EcolC_R0017 NC_010468.1 856578 856761 R 6S ribosomal RNA complement(856578..856761) Escherichia coli ATCC 8739 6065250 EcolC_R0031 rRNA EcolC_R0031 NC_010468.1 1181763 1183296 D 16S ribosomal RNA 1181763..1183296 Escherichia coli ATCC 8739 6065289 EcolC_R0033 rRNA EcolC_R0033 NC_010468.1 1183661 1186643 D 23S ribosomal RNA 1183661..1186643 Escherichia coli ATCC 8739 6067651 EcolC_R0034 rRNA EcolC_R0034 NC_010468.1 1186740 1186854 D 5S ribosomal RNA 1186740..1186854 Escherichia coli ATCC 8739 6066208 EcolC_R0087 rRNA EcolC_R0087 NC_010468.1 3770853 3770967 R 5S ribosomal RNA complement(3770853..3770967) Escherichia coli ATCC 8739 6068087 EcolC_R0088 rRNA EcolC_R0088 NC_010468.1 3771158 3774137 R 23S ribosomal RNA complement(3771158..3774137) Escherichia coli ATCC 8739 6068103 EcolC_R0091 rRNA EcolC_R0091 NC_010468.1 3774508 3776041 R 16S ribosomal RNA complement(3774508..3776041) Escherichia coli ATCC 8739 6068140 EcolC_R0102 rRNA EcolC_R0102 NC_010468.1 4420023 4420137 R 5S ribosomal RNA complement(4420023..4420137) Escherichia coli ATCC 8739 6064578 EcolC_R0103 rRNA EcolC_R0103 NC_010468.1 4420328 4423307 R 23S ribosomal RNA complement(4420328..4423307) Escherichia coli ATCC 8739 6064579 EcolC_R0105 rRNA EcolC_R0105 NC_010468.1 4423586 4425119 R 16S ribosomal RNA complement(4423586..4425119) Escherichia coli ATCC 8739 6064584 EcolC_R0110 rRNA EcolC_R0110 NC_010468.1 4460406 4460520 R 5S ribosomal RNA complement(4460406..4460520) Escherichia coli ATCC 8739 6065020 EcolC_R0111 rRNA EcolC_R0111 NC_010468.1 4460617 4463596 R 23S ribosomal RNA complement(4460617..4463596) Escherichia coli ATCC 8739 6065022 EcolC_R0113 rRNA EcolC_R0113 NC_010468.1 4463875 4465408 R 16S ribosomal RNA complement(4463875..4465408) Escherichia coli ATCC 8739 6065107 EcolC_R0116 rRNA EcolC_R0116 NC_010468.1 4591222 4591336 R 5S ribosomal RNA complement(4591222..4591336) Escherichia coli ATCC 8739 6066711 EcolC_R0117 rRNA EcolC_R0117 NC_010468.1 4591433 4594417 R 23S ribosomal RNA complement(4591433..4594417) Escherichia coli ATCC 8739 6066724 EcolC_R0120 rRNA EcolC_R0120 NC_010468.1 4594785 4596318 R 16S ribosomal RNA complement(4594785..4596318) Escherichia coli ATCC 8739 6066904 EcolC_R0127 rRNA EcolC_R0127 NC_010468.1 4683168 4683282 R 5S ribosomal RNA complement(4683168..4683282) Escherichia coli ATCC 8739 6067895 EcolC_R0128 rRNA EcolC_R0128 NC_010468.1 4683379 4686361 R 23S ribosomal RNA complement(4683379..4686361) Escherichia coli ATCC 8739 6067901 EcolC_R0130 rRNA EcolC_R0130 NC_010468.1 4686640 4688173 R 16S ribosomal RNA complement(4686640..4688173) Escherichia coli ATCC 8739 6067909