-- dump date 20140619_081638 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002925203.1 238899407 7956300 190..255 1 NC_012759.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 255 thrL 7956300 thrL Escherichia coli BW2952 thr operon leader peptide YP_002925203.1 190 D 595496 CDS YP_002925204.1 238899408 7956140 337..2799 1 NC_012759.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2799 thrA 7956140 thrA Escherichia coli BW2952 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002925204.1 337 D 595496 CDS YP_002925205.1 238899409 7953657 2801..3733 1 NC_012759.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3733 thrB 7953657 thrB Escherichia coli BW2952 homoserine kinase YP_002925205.1 2801 D 595496 CDS YP_002925206.1 238899410 7953919 3734..5020 1 NC_012759.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5020 thrC 7953919 thrC Escherichia coli BW2952 threonine synthase YP_002925206.1 3734 D 595496 CDS YP_002925207.1 238899411 7956146 5234..5530 1 NC_012759.1 MG1655 equivalent: b0005; hypothetical protein 5530 yaaX 7956146 yaaX Escherichia coli BW2952 hypothetical protein YP_002925207.1 5234 D 595496 CDS YP_002925208.1 238899412 7955438 complement(5683..6459) 1 NC_012759.1 MG1655 equivalent: b0006; hypothetical protein 6459 yaaA 7955438 yaaA Escherichia coli BW2952 hypothetical protein YP_002925208.1 5683 R 595496 CDS YP_002925209.1 238899413 7952753 complement(6529..7959) 1 NC_012759.1 MG1655 equivalent: b0007; putative transporter 7959 yaaJ 7952753 yaaJ Escherichia coli BW2952 putative transporter YP_002925209.1 6529 R 595496 CDS YP_002925210.1 238899414 7955646 8238..9191 1 NC_012759.1 MG1655 equivalent: b0008; transaldolase B 9191 talB 7955646 talB Escherichia coli BW2952 transaldolase B YP_002925210.1 8238 D 595496 CDS YP_002925211.1 238899415 7956165 9306..9893 1 NC_012759.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9893 mogA 7956165 mogA Escherichia coli BW2952 molybdenum cofactor biosynthesis protein MogA YP_002925211.1 9306 D 595496 CDS YP_002925212.1 238899416 7955164 complement(9928..10494) 1 NC_012759.1 MG1655 equivalent: b0010; hypothetical protein 10494 yaaH 7955164 yaaH Escherichia coli BW2952 hypothetical protein YP_002925212.1 9928 R 595496 CDS YP_002925213.1 238899417 7952740 complement(10643..11356) 1 NC_012759.1 MG1655 equivalent: b0011; hypothetical protein 11356 yaaW 7952740 yaaW Escherichia coli BW2952 hypothetical protein YP_002925213.1 10643 R 595496 CDS YP_002925214.1 238899418 7952754 complement(11382..11786) 1 NC_012759.1 MG1655 equivalent: b0013; hypothetical protein 11786 yaaI 7952754 yaaI Escherichia coli BW2952 hypothetical protein YP_002925214.1 11382 R 595496 CDS YP_002925215.1 238899419 7955333 12163..14079 1 NC_012759.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14079 dnaK 7955333 dnaK Escherichia coli BW2952 molecular chaperone DnaK YP_002925215.1 12163 D 595496 CDS YP_002925216.1 238899420 7952628 14168..15298 1 NC_012759.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 15298 dnaJ 7952628 dnaJ Escherichia coli BW2952 chaperone protein DnaJ YP_002925216.1 14168 D 595496 CDS YP_002925217.1 238899421 7952627 15445..16557 1 NC_012759.1 MG1655 equivalent: b0016; IS186/IS421 transposase 16557 insL 7952627 insL Escherichia coli BW2952 IS186/IS421 transposase YP_002925217.1 15445 D 595496 CDS YP_002925218.1 238899422 7954025 complement(16751..16960) 1 NC_012759.1 MG1655 equivalent: b0018; regulatory protein for HokC, overlaps CDS of hokC 16960 mokC 7954025 mokC Escherichia coli BW2952 regulatory protein for HokC, overlaps CDS of hokC YP_002925218.1 16751 R 595496 CDS YP_002925219.1 238899423 7955932 complement(16751..16903) 1 NC_012759.1 MG1655 equivalent: b4412; toxic membrane protein, small 16903 hokC 7955932 hokC Escherichia coli BW2952 toxic membrane protein, small YP_002925219.1 16751 R 595496 CDS YP_002925220.1 238899424 7952167 17489..18655 1 NC_012759.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 18655 nhaA 7952167 nhaA Escherichia coli BW2952 pH-dependent sodium/proton antiporter YP_002925220.1 17489 D 595496 CDS YP_002925221.1 238899425 7956057 18715..19620 1 NC_012759.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 19620 nhaR 7956057 nhaR Escherichia coli BW2952 transcriptional activator NhaR YP_002925221.1 18715 D 595496 CDS YP_002925222.1 238899426 7953375 complement(19811..20314) 1 NC_012759.1 MG1655 equivalent: b0021; IS1 transposase InsAB' 20314 insB 7953375 insB Escherichia coli BW2952 IS1 transposase InsAB' YP_002925222.1 19811 R 595496 CDS YP_002925223.1 238899427 7954020 complement(20233..20508) 1 NC_012759.1 MG1655 equivalent: b0022; KpLE2 phage-like element; IS1 repressor protein InsA 20508 insA 7954020 insA Escherichia coli BW2952 KpLE2 phage-like element; IS1 repressor protein InsA YP_002925223.1 20233 R 595496 CDS YP_002925224.1 238899428 7954067 complement(20815..21078) 1 NC_012759.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 21078 rpsT 7954067 rpsT Escherichia coli BW2952 30S ribosomal protein S20 YP_002925224.1 20815 R 595496 CDS YP_002925225.1 238899429 7952284 21181..21399 1 NC_012759.1 MG1655 equivalent: b0024; hypothetical protein 21399 yaaY 7952284 yaaY Escherichia coli BW2952 hypothetical protein YP_002925225.1 21181 D 595496 CDS YP_002925226.1 238899430 7955439 21407..22348 1 NC_012759.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 22348 ribF 7955439 ribF Escherichia coli BW2952 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002925226.1 21407 D 595496 CDS YP_002925227.1 238899431 7952573 22391..25207 1 NC_012759.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 25207 ileS 7952573 ileS Escherichia coli BW2952 isoleucyl-tRNA synthetase YP_002925227.1 22391 D 595496 CDS YP_002925228.1 238899432 7954053 25207..25701 1 NC_012759.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 25701 lspA 7954053 lspA Escherichia coli BW2952 lipoprotein signal peptidase YP_002925228.1 25207 D 595496 CDS YP_002925229.1 238899433 7955771 25826..26275 1 NC_012759.1 MG1655 equivalent: b0028; FKBP-type peptidyl-prolyl cis-trans isomerase 26275 fkpB 7955771 fkpB Escherichia coli BW2952 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002925229.1 25826 D 595496 CDS YP_002925230.1 238899434 7953580 26277..27227 1 NC_012759.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 27227 ispH 7953580 ispH Escherichia coli BW2952 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002925230.1 26277 D 595496 CDS YP_002925231.1 238899435 7952229 27293..28207 1 NC_012759.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 28207 rihC 7952229 rihC Escherichia coli BW2952 ribonucleoside hydrolase RihC YP_002925231.1 27293 D 595496 CDS YP_002925232.1 238899436 7955968 28374..29195 1 NC_012759.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 29195 dapB 7955968 dapB Escherichia coli BW2952 dihydrodipicolinate reductase YP_002925232.1 28374 D 595496 CDS YP_002925233.1 238899437 7953249 29651..30799 1 NC_012759.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 30799 carA 7953249 carA Escherichia coli BW2952 carbamoyl phosphate synthase small subunit YP_002925233.1 29651 D 595496 CDS YP_002925234.1 238899438 7952593 30817..34038 1 NC_012759.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 34038 carB 7952593 carB Escherichia coli BW2952 carbamoyl phosphate synthase large subunit YP_002925234.1 30817 D 595496 CDS YP_002925235.1 238899439 7952594 34300..34695 1 NC_012759.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 34695 caiF 7952594 caiF Escherichia coli BW2952 DNA-binding transcriptional activator CaiF YP_002925235.1 34300 D 595496 CDS YP_002925236.1 238899440 7953376 complement(34781..35371) 1 NC_012759.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 35371 caiE 7953376 caiE Escherichia coli BW2952 carnitine operon protein CaiE YP_002925236.1 34781 R 595496 CDS YP_002925237.1 238899441 7954605 complement(35377..36270) 1 NC_012759.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 36270 caiD 7954605 caiD Escherichia coli BW2952 carnitinyl-CoA dehydratase YP_002925237.1 35377 R 595496 CDS YP_002925238.1 238899442 7953163 complement(36271..37839) 1 NC_012759.1 MG1655 equivalent: b0037; putative crotonobetaine/carnitine-CoA ligase 37839 caiC 7953163 caiC Escherichia coli BW2952 putative crotonobetaine/carnitine-CoA ligase YP_002925238.1 36271 R 595496 CDS YP_002925239.1 238899443 7954701 complement(37898..39115) 1 NC_012759.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 39115 caiB 7954701 caiB Escherichia coli BW2952 crotonobetainyl-CoA:carnitine CoA-transferase YP_002925239.1 37898 R 595496 CDS YP_002925240.1 238899444 7953164 complement(39244..40386) 1 NC_012759.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 40386 caiA 7953164 caiA Escherichia coli BW2952 crotonobetainyl-CoA dehydrogenase YP_002925240.1 39244 R 595496 CDS YP_002925241.1 238899445 7953162 complement(40417..41931) 1 NC_012759.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 41931 caiT 7953162 caiT Escherichia coli BW2952 L-carnitine/gamma-butyrobetaine antiporter YP_002925241.1 40417 R 595496 CDS YP_002925242.1 238899446 7955647 42403..43173 1 NC_012759.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 43173 fixA 7955647 fixA Escherichia coli BW2952 putative electron transfer flavoprotein FixA YP_002925242.1 42403 D 595496 CDS YP_002925243.1 238899447 7954829 43188..44129 1 NC_012759.1 involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 44129 fixB 7954829 fixB Escherichia coli BW2952 putative electron transfer flavoprotein FixB YP_002925243.1 43188 D 595496 CDS YP_002925244.1 238899448 7954831 44180..45466 1 NC_012759.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 45466 fixC 7954831 fixC Escherichia coli BW2952 putative oxidoreductase FixC YP_002925244.1 44180 D 595496 CDS YP_002925245.1 238899449 7955241 45463..45750 1 NC_012759.1 MG1655 equivalent: b0044; putative 4Fe-4S ferredoxin-type protein 45750 fixX 7955241 fixX Escherichia coli BW2952 putative 4Fe-4S ferredoxin-type protein YP_002925245.1 45463 D 595496 CDS YP_002925246.1 238899450 7954592 45807..47138 1 NC_012759.1 MG1655 equivalent: b0045; putative transporter 47138 yaaU 7954592 yaaU Escherichia coli BW2952 putative transporter YP_002925246.1 45807 D 595496 CDS YP_002925247.1 238899451 7955677 47246..47776 1 NC_012759.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 47776 kefF 7955677 kefF Escherichia coli BW2952 glutathione-regulated potassium-efflux system ancillary protein KefF YP_002925247.1 47246 D 595496 CDS YP_002925248.1 238899452 7953611 47769..49631 1 NC_012759.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 49631 kefC 7953611 kefC Escherichia coli BW2952 glutathione-regulated potassium-efflux system protein KefC YP_002925248.1 47769 D 595496 CDS YP_002925249.1 238899453 7954579 49823..50302 1 NC_012759.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 50302 folA 7954579 folA Escherichia coli BW2952 dihydrofolate reductase YP_002925249.1 49823 D 595496 CDS YP_002925250.1 238899454 7953251 complement(50380..51222) 1 NC_012759.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 51222 apaH 7953251 apaH Escherichia coli BW2952 diadenosine tetraphosphatase YP_002925250.1 50380 R 595496 CDS YP_002925251.1 238899455 7953246 complement(51229..51606) 1 NC_012759.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 51606 apaG 7953246 apaG Escherichia coli BW2952 ApaG protein YP_002925251.1 51229 R 595496 CDS YP_002925252.1 238899456 7955782 complement(51609..52430) 1 NC_012759.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 52430 ksgA 7955782 ksgA Escherichia coli BW2952 dimethyladenosine transferase YP_002925252.1 51609 R 595496 CDS YP_002925253.1 238899457 7956000 complement(52427..53416) 1 NC_012759.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 53416 pdxA 7956000 pdxA Escherichia coli BW2952 4-hydroxythreonine-4-phosphate dehydrogenase YP_002925253.1 52427 R 595496 CDS YP_002925254.1 238899458 7952333 complement(53416..54702) 1 NC_012759.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 54702 surA 7952333 surA Escherichia coli BW2952 peptidyl-prolyl cis-trans isomerase SurA YP_002925254.1 53416 R 595496 CDS YP_002925255.1 238899459 7954480 complement(54755..57109) 1 NC_012759.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 57109 imp 7954480 imp Escherichia coli BW2952 organic solvent tolerance protein YP_002925255.1 54755 R 595496 CDS YP_002925256.1 238899460 7953551 57364..58179 1 NC_012759.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 58179 djlA 7953551 djlA Escherichia coli BW2952 Dna-J like membrane chaperone protein YP_002925256.1 57364 D 595496 CDS YP_002925257.1 238899461 7953489 complement(59687..60346) 1 NC_012759.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 60346 rluA 7953489 rluA Escherichia coli BW2952 23S rRNA/tRNA pseudouridine synthase A YP_002925257.1 59687 R 595496 CDS YP_002925258.1 238899462 7955820 complement(60358..63264) 1 NC_012759.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 63264 hepA 7955820 hepA Escherichia coli BW2952 ATP-dependent helicase HepA YP_002925258.1 60358 R 595496 CDS YP_002925259.1 238899463 7955993 complement(63429..65780) 1 NC_012759.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 65780 polB 7955993 polB Escherichia coli BW2952 DNA polymerase II YP_002925259.1 63429 R 595496 CDS YP_002925260.1 238899464 7952210 complement(66834..68336) 1 NC_012759.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 68336 araA 7952210 araA Escherichia coli BW2952 L-arabinose isomerase YP_002925260.1 66834 R 595496 CDS YP_002925261.1 238899465 7954115 complement(68347..70047) 1 NC_012759.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 70047 araB 7954115 araB Escherichia coli BW2952 ribulokinase YP_002925261.1 68347 R 595496 CDS YP_002925262.1 238899466 7954167 70386..71264 1 NC_012759.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; AraC family transcriptional regulator 71264 araC 7954167 araC Escherichia coli BW2952 AraC family transcriptional regulator YP_002925262.1 70386 D 595496 CDS YP_002925263.1 238899467 7953418 71350..72114 1 NC_012759.1 MG1655 equivalent: b0065; hypothetical protein 72114 yabI 7953418 yabI Escherichia coli BW2952 hypothetical protein YP_002925263.1 71350 D 595496 CDS YP_002925264.1 238899468 7952698 complement(72228..72926) 1 NC_012759.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 72926 thiQ 7952698 thiQ Escherichia coli BW2952 thiamine transporter ATP-binding subunit YP_002925264.1 72228 R 595496 CDS YP_002925265.1 238899469 7956130 complement(72910..74520) 1 NC_012759.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 74520 thiP 7956130 thiP Escherichia coli BW2952 thiamine transporter membrane protein YP_002925265.1 72910 R 595496 CDS YP_002925266.1 238899470 7953745 complement(74496..75479) 1 NC_012759.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 75479 tbpA 7953745 tbpA Escherichia coli BW2952 thiamine transporter substrate binding subunit YP_002925266.1 74496 R 595496 CDS YP_002925267.1 238899471 7956131 complement(75643..77298) 1 NC_012759.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 77298 sgrR 7956131 sgrR Escherichia coli BW2952 transcriptional regulator SgrR YP_002925267.1 75643 R 595496 CDS YP_002925268.1 238899472 7952168 77620..78798 1 NC_012759.1 MG1655 equivalent: b0070; broad specificity sugar efflux system 78798 setA 7952168 setA Escherichia coli BW2952 broad specificity sugar efflux system YP_002925268.1 77620 D 595496 CDS YP_002925269.1 238899473 7952585 complement(78847..79452) 1 NC_012759.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 79452 leuD 7952585 leuD Escherichia coli BW2952 isopropylmalate isomerase small subunit YP_002925269.1 78847 R 595496 CDS YP_002925270.1 238899474 7952306 complement(79463..80863) 1 NC_012759.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 80863 leuC 7952306 leuC Escherichia coli BW2952 isopropylmalate isomerase large subunit YP_002925270.1 79463 R 595496 CDS YP_002925271.1 238899475 7952307 complement(80866..81957) 1 NC_012759.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 81957 leuB 7952307 leuB Escherichia coli BW2952 3-isopropylmalate dehydrogenase YP_002925271.1 80866 R 595496 CDS YP_002925272.1 238899476 7952305 complement(81957..83528) 1 NC_012759.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 83528 leuA 7952305 leuA Escherichia coli BW2952 2-isopropylmalate synthase YP_002925272.1 81957 R 595496 CDS YP_002925273.1 238899477 7952259 complement(83621..83707) 1 NC_012759.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 83707 leuL 7952259 leuL Escherichia coli BW2952 leu operon leader peptide YP_002925273.1 83621 R 595496 CDS YP_002925274.1 238899478 7954124 84367..85311 1 NC_012759.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 85311 leuO 7954124 leuO Escherichia coli BW2952 leucine transcriptional activator YP_002925274.1 84367 D 595496 CDS YP_002925275.1 238899479 7953377 85629..87353 1 NC_012759.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 87353 ilvI 7953377 ilvI Escherichia coli BW2952 acetolactate synthase 3 catalytic subunit YP_002925275.1 85629 D 595496 CDS YP_002925276.1 238899480 7952393 87356..87847 1 NC_012759.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 87847 ilvH 7952393 ilvH Escherichia coli BW2952 acetolactate synthase 3 regulatory subunit YP_002925276.1 87356 D 595496 CDS YP_002925277.1 238899481 7952394 88027..89031 1 NC_012759.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 89031 fruR 7952394 fruR Escherichia coli BW2952 DNA-binding transcriptional regulator FruR YP_002925277.1 88027 D 595496 CDS YP_002925278.1 238899482 7953419 89633..90091 1 NC_012759.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 90091 mraZ 7953419 mraZ Escherichia coli BW2952 cell division protein MraZ YP_002925278.1 89633 D 595496 CDS YP_002925279.1 238899483 7952914 90093..91034 1 NC_012759.1 MG1655 equivalent: b0082; S-adenosyl-methyltransferase MraW 91034 mraW 7952914 mraW Escherichia coli BW2952 S-adenosyl-methyltransferase MraW YP_002925279.1 90093 D 595496 CDS YP_002925280.1 238899484 7955997 91031..91396 1 NC_012759.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 91396 ftsL 7955997 ftsL Escherichia coli BW2952 cell division protein FtsL YP_002925280.1 91031 D 595496 CDS YP_002925281.1 238899485 7954226 91412..93178 1 NC_012759.1 MG1655 equivalent: b0084; transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 93178 ftsI 7954226 ftsI Escherichia coli BW2952 transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) YP_002925281.1 91412 D 595496 CDS YP_002925282.1 238899486 7956178 93165..94652 1 NC_012759.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 94652 murE 7956178 murE Escherichia coli BW2952 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002925282.1 93165 D 595496 CDS YP_002925283.1 238899487 7956244 94649..96007 1 NC_012759.1 MG1655 equivalent: b0086; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 96007 murF 7956244 murF Escherichia coli BW2952 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002925283.1 94649 D 595496 CDS YP_002925284.1 238899488 7956245 96001..97083 1 NC_012759.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 97083 mraY 7956245 mraY Escherichia coli BW2952 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002925284.1 96001 D 595496 CDS YP_002925285.1 238899489 7954543 97086..98402 1 NC_012759.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 98402 murD 7954543 murD Escherichia coli BW2952 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002925285.1 97086 D 595496 CDS YP_002925286.1 238899490 7956243 98402..99646 1 NC_012759.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 99646 ftsW 7956243 ftsW Escherichia coli BW2952 cell division protein FtsW YP_002925286.1 98402 D 595496 CDS YP_002925287.1 238899491 7954009 99643..100710 1 NC_012759.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 100710 murG 7954009 murG Escherichia coli BW2952 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002925287.1 99643 D 595496 CDS YP_002925288.1 238899492 7954342 100764..102239 1 NC_012759.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 102239 murC 7954342 murC Escherichia coli BW2952 UDP-N-acetylmuramate--L-alanine ligase YP_002925288.1 100764 D 595496 CDS YP_002925289.1 238899493 7956241 102232..103152 1 NC_012759.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 103152 ddl 7956241 ddl Escherichia coli BW2952 D-alanine--D-alanine ligase YP_002925289.1 102232 D 595496 CDS YP_002925290.1 238899494 7953215 103154..103984 1 NC_012759.1 involved in septum formation; cell division protein FtsQ 103984 ftsQ 7953215 ftsQ Escherichia coli BW2952 cell division protein FtsQ YP_002925290.1 103154 D 595496 CDS YP_002925291.1 238899495 7954223 103981..105243 1 NC_012759.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 105243 ftsA 7954223 ftsA Escherichia coli BW2952 cell division protein FtsA YP_002925291.1 103981 D 595496 CDS YP_002925292.1 238899496 7952528 105304..106455 1 NC_012759.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 106455 ftsZ 7952528 ftsZ Escherichia coli BW2952 cell division protein FtsZ YP_002925292.1 105304 D 595496 CDS YP_002925293.1 238899497 7953883 106556..107473 1 NC_012759.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 107473 lpxC 7953883 lpxC Escherichia coli BW2952 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002925293.1 106556 D 595496 CDS YP_002925294.1 238899498 7956227 107704..108216 1 NC_012759.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 108216 secM 7956227 secM Escherichia coli BW2952 SecA regulator SecM YP_002925294.1 107704 D 595496 CDS YP_002925295.1 238899499 7955924 108278..110983 1 NC_012759.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 110983 secA 7955924 secA Escherichia coli BW2952 preprotein translocase subunit SecA YP_002925295.1 108278 D 595496 CDS YP_002925296.1 238899500 7955763 111043..111432 1 NC_012759.1 MG1655 equivalent: b0099; nucleoside triphosphate pyrophosphohydrolase 111432 mutT 7955763 mutT Escherichia coli BW2952 nucleoside triphosphate pyrophosphohydrolase YP_002925296.1 111043 D 595496 CDS YP_002925297.1 238899501 7954413 complement(111648..111845) 1 NC_012759.1 MG1655 equivalent: b0101; zinc-binding protein 111845 yacG 7954413 yacG Escherichia coli BW2952 zinc-binding protein YP_002925297.1 111648 R 595496 CDS YP_002925298.1 238899502 7952755 complement(111855..112598) 1 NC_012759.1 MG1655 equivalent: b0102; hypothetical protein 112598 yacF 7952755 yacF Escherichia coli BW2952 hypothetical protein YP_002925298.1 111855 R 595496 CDS YP_002925299.1 238899503 7952756 complement(112598..113218) 1 NC_012759.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 113218 coaE 7952756 coaE Escherichia coli BW2952 dephospho-CoA kinase YP_002925299.1 112598 R 595496 CDS YP_002925300.1 238899504 7953238 113443..114486 1 NC_012759.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 114486 guaC 7953238 guaC Escherichia coli BW2952 guanosine 5'-monophosphate oxidoreductase YP_002925300.1 113443 D 595496 CDS YP_002925301.1 238899505 7953872 complement(114521..115723) 1 NC_012759.1 MG1655 equivalent: b0106; type IV pilin biogenesis protein 115723 hofC 7953872 hofC Escherichia coli BW2952 type IV pilin biogenesis protein YP_002925301.1 114521 R 595496 CDS YP_002925302.1 238899506 7952520 complement(115713..117098) 1 NC_012759.1 MG1655 equivalent: b0107; hypothetical protein 117098 hofB 7952520 hofB Escherichia coli BW2952 hypothetical protein YP_002925302.1 115713 R 595496 CDS YP_002925303.1 238899507 7953083 complement(117108..117548) 1 NC_012759.1 MG1655 equivalent: b0108; putative major pilin subunit 117548 ppdD 7953083 ppdD Escherichia coli BW2952 putative major pilin subunit YP_002925303.1 117108 R 595496 CDS YP_002925304.1 238899508 7955131 complement(117751..118644) 1 NC_012759.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 118644 nadC 7955131 nadC Escherichia coli BW2952 quinolinate phosphoribosyltransferase YP_002925304.1 117751 R 595496 CDS YP_002925305.1 238899509 7955886 118732..119283 1 NC_012759.1 MG1655 equivalent: b0110; N-acetyl-anhydromuranmyl-L-alanine amidase 119283 ampD 7955886 ampD Escherichia coli BW2952 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002925305.1 118732 D 595496 CDS YP_002925306.1 238899510 7954334 119280..120134 1 NC_012759.1 involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 120134 ampE 7954334 ampE Escherichia coli BW2952 regulatory protein AmpE YP_002925306.1 119280 D 595496 CDS YP_002925307.1 238899511 7955022 complement(120177..121550) 1 NC_012759.1 MG1655 equivalent: b0112; aromatic amino acid transporter 121550 aroP 7955022 aroP Escherichia coli BW2952 aromatic amino acid transporter YP_002925307.1 120177 R 595496 CDS YP_002925308.1 238899512 7952504 122091..122855 1 NC_012759.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 122855 pdhR 7952504 pdhR Escherichia coli BW2952 transcriptional regulator PdhR YP_002925308.1 122091 D 595496 CDS YP_002925309.1 238899513 7953420 123016..125679 1 NC_012759.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 125679 aceE 7953420 aceE Escherichia coli BW2952 pyruvate dehydrogenase subunit E1 YP_002925309.1 123016 D 595496 CDS YP_002925310.1 238899514 7955845 125694..127586 1 NC_012759.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 127586 aceF 7955845 aceF Escherichia coli BW2952 dihydrolipoamide acetyltransferase YP_002925310.1 125694 D 595496 CDS YP_002925311.1 238899515 7955846 127911..129335 1 NC_012759.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 129335 lpd 7955846 lpd Escherichia coli BW2952 dihydrolipoamide dehydrogenase YP_002925311.1 127911 D 595496 CDS YP_002925312.1 238899516 7954146 complement(129406..131259) 1 NC_012759.1 MG1655 equivalent: b0117; hypothetical protein 131259 yacH 7954146 yacH Escherichia coli BW2952 hypothetical protein YP_002925312.1 129406 R 595496 CDS YP_002925313.1 238899517 7955334 131614..134211 1 NC_012759.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 134211 acnB 7955334 acnB Escherichia coli BW2952 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002925313.1 131614 D 595496 CDS YP_002925314.1 238899518 7952561 134387..134749 1 NC_012759.1 MG1655 equivalent: b0119; hypothetical protein 134749 yacL 7952561 yacL Escherichia coli BW2952 hypothetical protein YP_002925314.1 134387 D 595496 CDS YP_002925315.1 238899519 7952915 complement(134787..135581) 1 NC_012759.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 135581 speD 7952915 speD Escherichia coli BW2952 S-adenosylmethionine decarboxylase YP_002925315.1 134787 R 595496 CDS YP_002925316.1 238899520 7955998 complement(135597..136463) 1 NC_012759.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 136463 speE 7955998 speE Escherichia coli BW2952 spermidine synthase YP_002925316.1 135597 R 595496 CDS YP_002925317.1 238899521 7956062 complement(136569..136916) 1 NC_012759.1 MG1655 equivalent: b0122; hypothetical protein 136916 yacC 7956062 yacC Escherichia coli BW2952 hypothetical protein YP_002925317.1 136569 R 595496 CDS YP_002925318.1 238899522 7955335 137082..138632 1 NC_012759.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 138632 cueO 7955335 cueO Escherichia coli BW2952 multicopper oxidase YP_002925318.1 137082 D 595496 CDS YP_002925319.1 238899523 7954296 complement(138834..141224) 1 NC_012759.1 MG1655 equivalent: b0124; glucose dehydrogenase 141224 gcd 7954296 gcd Escherichia coli BW2952 glucose dehydrogenase YP_002925319.1 138834 R 595496 CDS YP_002925320.1 238899524 7953803 141430..141966 1 NC_012759.1 MG1655 equivalent: b0125; hypoxanthine phosphoribosyltransferase 141966 hpt 7953803 hpt Escherichia coli BW2952 hypoxanthine phosphoribosyltransferase YP_002925320.1 141430 D 595496 CDS YP_002925321.1 238899525 7953988 complement(142007..142669) 1 NC_012759.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 142669 can 7953988 can Escherichia coli BW2952 carbonic anhydrase YP_002925321.1 142007 R 595496 CDS YP_002925322.1 238899526 7952597 142778..143704 1 NC_012759.1 MG1655 equivalent: b0127; putative transporter subunit: ATP-binding component of ABC superfamily 143704 yadG 7952597 yadG Escherichia coli BW2952 putative transporter subunit: ATP-binding component of ABC superfamily YP_002925322.1 142778 D 595496 CDS YP_002925323.1 238899527 7955720 143701..144471 1 NC_012759.1 MG1655 equivalent: b0128; putative transporter subunit: membrane component of ABC superfamily 144471 yadH 7955720 yadH Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002925323.1 143701 D 595496 CDS YP_002925324.1 238899528 7955733 144576..145016 1 NC_012759.1 MG1655 equivalent: b0129; putative PTS Enzyme IIA 145016 yadI 7955733 yadI Escherichia coli BW2952 putative PTS Enzyme IIA YP_002925324.1 144576 D 595496 CDS YP_002925325.1 238899529 7955549 145080..146309 1 NC_012759.1 MG1655 equivalent: b0130; putative polysaccharide deacetylase lipoprotein 146309 yadE 7955549 yadE Escherichia coli BW2952 putative polysaccharide deacetylase lipoprotein YP_002925325.1 145080 D 595496 CDS YP_002925326.1 238899530 7955326 complement(146313..146693) 1 NC_012759.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 146693 panD 7955326 panD Escherichia coli BW2952 aspartate alpha-decarboxylase YP_002925326.1 146313 R 595496 CDS YP_002925327.1 238899531 7952510 146967..147869 1 NC_012759.1 MG1655 equivalent: b0132; putative transposase 147869 yadD 7952510 yadD Escherichia coli BW2952 putative transposase YP_002925327.1 146967 D 595496 CDS YP_002925328.1 238899532 7955739 complement(147943..148794) 1 NC_012759.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 148794 panC 7955739 panC Escherichia coli BW2952 pantoate--beta-alanine ligase YP_002925328.1 147943 R 595496 CDS YP_002925329.1 238899533 7954465 complement(148806..149600) 1 NC_012759.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 149600 panB 7954465 panB Escherichia coli BW2952 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002925329.1 148806 R 595496 CDS YP_002925330.1 238899534 7952312 complement(149714..150952) 1 NC_012759.1 MG1655 equivalent: b0135; putative fimbrial-like adhesin protein 150952 yadC 7952312 yadC Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925330.1 149714 R 595496 CDS YP_002925331.1 238899535 7954876 complement(151002..151598) 1 NC_012759.1 MG1655 equivalent: b0136; putative fimbrial-like adhesin protein 151598 yadK 7954876 yadK Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925331.1 151002 R 595496 CDS YP_002925332.1 238899536 7954877 complement(151625..152230) 1 NC_012759.1 MG1655 equivalent: b0137; putative fimbrial-like adhesin protein 152230 yadL 7954877 yadL Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925332.1 151625 R 595496 CDS YP_002925333.1 238899537 7954878 complement(152242..152811) 1 NC_012759.1 MG1655 equivalent: b0138; putative fimbrial-like adhesin protein 152811 yadM 7954878 yadM Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925333.1 152242 R 595496 CDS YP_002925334.1 238899538 7954879 complement(152828..155425) 1 NC_012759.1 similar to the fimbrial usher protein PapC; putative outer membrane usher protein 155425 htrE 7954879 htrE Escherichia coli BW2952 putative outer membrane usher protein YP_002925334.1 152828 R 595496 CDS YP_002925335.1 238899539 7955218 complement(155460..156200) 1 NC_012759.1 MG1655 equivalent: b0140; putative chaperone protein EcpD 156200 ecpD 7955218 ecpD Escherichia coli BW2952 putative chaperone protein EcpD YP_002925335.1 155460 R 595496 CDS YP_002925336.1 238899540 7955300 complement(156298..156882) 1 NC_012759.1 MG1655 equivalent: b0141; putative fimbrial-like adhesin protein 156882 yadN 7955300 yadN Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925336.1 156298 R 595496 CDS YP_002925337.1 238899541 7954880 complement(157252..157731) 1 NC_012759.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 157731 folK 7954880 folK Escherichia coli BW2952 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002925337.1 157252 R 595496 CDS YP_002925338.1 238899542 7952252 complement(157728..159125) 1 NC_012759.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 159125 pcnB 7952252 pcnB Escherichia coli BW2952 poly(A) polymerase I YP_002925338.1 157728 R 595496 CDS YP_002925339.1 238899543 7954562 complement(159185..160081) 1 NC_012759.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 160081 yadB 7954562 yadB Escherichia coli BW2952 glutamyl-Q tRNA(Asp) synthetase YP_002925339.1 159185 R 595496 CDS YP_002925340.1 238899544 7953832 complement(160148..160603) 1 NC_012759.1 MG1655 equivalent: b0145; RNA polymerase-binding transcription factor 160603 dksA 7953832 dksA Escherichia coli BW2952 RNA polymerase-binding transcription factor YP_002925340.1 160148 R 595496 CDS YP_002925341.1 238899545 7953447 complement(160781..161485) 1 NC_012759.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 161485 sfsA 7953447 sfsA Escherichia coli BW2952 sugar fermentation stimulation protein A YP_002925341.1 160781 R 595496 CDS YP_002925342.1 238899546 7954744 complement(161500..162030) 1 NC_012759.1 MG1655 equivalent: b0147; 2'-5' RNA ligase 162030 ligT 7954744 ligT Escherichia coli BW2952 2'-5' RNA ligase YP_002925342.1 161500 R 595496 CDS YP_002925343.1 238899547 7952251 162104..164533 1 NC_012759.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 164533 hrpB 7952251 hrpB Escherichia coli BW2952 ATP-dependent RNA helicase HrpB YP_002925343.1 162104 D 595496 CDS YP_002925344.1 238899548 7954663 164729..167263 1 NC_012759.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 167263 mrcB 7954663 mrcB Escherichia coli BW2952 penicillin-binding protein 1b YP_002925344.1 164729 D 595496 CDS YP_002925345.1 238899549 7953685 167483..169726 1 NC_012759.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 169726 fhuA 7953685 fhuA Escherichia coli BW2952 ferrichrome outer membrane transporter YP_002925345.1 167483 D 595496 CDS YP_002925346.1 238899550 7953570 169777..170574 1 NC_012759.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 170574 fhuC 7953570 fhuC Escherichia coli BW2952 iron-hydroxamate transporter ATP-binding subunit YP_002925346.1 169777 D 595496 CDS YP_002925347.1 238899551 7954018 170574..171464 1 NC_012759.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 171464 fhuD 7954018 fhuD Escherichia coli BW2952 iron-hydroxamate transporter substrate-binding subunit YP_002925347.1 170574 D 595496 CDS YP_002925348.1 238899552 7954019 171461..173443 1 NC_012759.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 173443 fhuB 7954019 fhuB Escherichia coli BW2952 iron-hydroxamate transporter permease subunit YP_002925348.1 171461 D 595496 CDS YP_002925349.1 238899553 7953690 complement(173601..174881) 1 NC_012759.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 174881 hemL 7953690 hemL Escherichia coli BW2952 glutamate-1-semialdehyde aminotransferase YP_002925349.1 173601 R 595496 CDS YP_002925350.1 238899554 7953826 175106..176527 1 NC_012759.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 176527 clcA 7953826 clcA Escherichia coli BW2952 chloride channel protein YP_002925350.1 175106 D 595496 CDS YP_002925351.1 238899555 7952634 176609..176953 1 NC_012759.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 176953 erpA 7952634 erpA Escherichia coli BW2952 iron-sulfur cluster insertion protein ErpA YP_002925351.1 176609 D 595496 CDS YP_002925352.1 238899556 7952916 complement(177000..177623) 1 NC_012759.1 MG1655 equivalent: b0157; hypothetical protein 177623 yadS 7952916 yadS Escherichia coli BW2952 hypothetical protein YP_002925352.1 177000 R 595496 CDS YP_002925353.1 238899557 7952662 complement(177661..178461) 1 NC_012759.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 178461 btuF 7952662 btuF Escherichia coli BW2952 vitamin B12-transporter protein BtuF YP_002925353.1 177661 R 595496 CDS YP_002925354.1 238899558 7956273 complement(178454..179152) 1 NC_012759.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 179152 mtn 7956273 mtn Escherichia coli BW2952 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002925354.1 178454 R 595496 CDS YP_002925355.1 238899559 7952375 179236..180753 1 NC_012759.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 180753 dgt 7952375 dgt Escherichia coli BW2952 deoxyguanosinetriphosphate triphosphohydrolase YP_002925355.1 179236 D 595496 CDS YP_002925356.1 238899560 7953234 180883..182307 1 NC_012759.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 182307 degP 7953234 degP Escherichia coli BW2952 serine endoprotease YP_002925356.1 180883 D 595496 CDS YP_002925357.1 238899561 7956029 182462..183619 1 NC_012759.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 183619 cdaR 7956029 cdaR Escherichia coli BW2952 carbohydrate diacid transcriptional activator CdaR YP_002925357.1 182462 D 595496 CDS YP_002925358.1 238899562 7953378 complement(183708..184094) 1 NC_012759.1 MG1655 equivalent: b0163; hypothetical protein 184094 yaeH 7953378 yaeH Escherichia coli BW2952 hypothetical protein YP_002925358.1 183708 R 595496 CDS YP_002925359.1 238899563 7952757 complement(184256..185068) 1 NC_012759.1 MG1655 equivalent: b0164; phosphodiesterase YaeI 185068 yaeI 7952757 yaeI Escherichia coli BW2952 phosphodiesterase YaeI YP_002925359.1 184256 R 595496 CDS YP_002925360.1 238899564 7955310 complement(185122..185946) 1 NC_012759.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 185946 dapD 7955310 dapD Escherichia coli BW2952 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002925360.1 185122 R 595496 CDS YP_002925361.1 238899565 7952231 complement(185977..188649) 1 NC_012759.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 188649 glnD 7952231 glnD Escherichia coli BW2952 PII uridylyl-transferase YP_002925361.1 185977 R 595496 CDS YP_002925362.1 238899566 7956265 complement(188711..189505) 1 NC_012759.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 189505 map 7956265 map Escherichia coli BW2952 methionine aminopeptidase YP_002925362.1 188711 R 595496 CDS YP_002925363.1 238899567 7952169 189873..190598 1 NC_012759.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 190598 rpsB 7952169 rpsB Escherichia coli BW2952 30S ribosomal protein S2 YP_002925363.1 189873 D 595496 CDS YP_002925364.1 238899568 7952283 190856..191707 1 NC_012759.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 191707 tsf 7952283 tsf Escherichia coli BW2952 elongation factor Ts YP_002925364.1 190856 D 595496 CDS YP_002925365.1 238899569 7955786 191854..192579 1 NC_012759.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 192579 pyrH 7955786 pyrH Escherichia coli BW2952 uridylate kinase YP_002925365.1 191854 D 595496 CDS YP_002925366.1 238899570 7956264 192871..193428 1 NC_012759.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 193428 frr 7956264 frr Escherichia coli BW2952 ribosome recycling factor YP_002925366.1 192871 D 595496 CDS YP_002925367.1 238899571 7955978 193520..194716 1 NC_012759.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 194716 dxr 7955978 dxr Escherichia coli BW2952 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002925367.1 193520 D 595496 CDS YP_002925368.1 238899572 7952227 194902..195663 1 NC_012759.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 195663 ispU 7952227 ispU Escherichia coli BW2952 UDP pyrophosphate synthase YP_002925368.1 194902 D 595496 CDS YP_002925369.1 238899573 7956252 195676..196533 1 NC_012759.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 196533 cdsA 7956252 cdsA Escherichia coli BW2952 CDP-diglyceride synthase YP_002925369.1 195676 D 595496 CDS YP_002925370.1 238899574 7952613 196545..197897 1 NC_012759.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 197897 rseP 7952613 rseP Escherichia coli BW2952 zinc metallopeptidase RseP YP_002925370.1 196545 D 595496 CDS YP_002925371.1 238899575 7956283 197927..200359 1 NC_012759.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 200359 bamA 7956283 bamA Escherichia coli BW2952 outer membrane protein assembly factor YaeT YP_002925371.1 197927 D 595496 CDS YP_002925372.1 238899576 7952917 200481..200966 1 NC_012759.1 MG1655 equivalent: b0178; periplasmic chaperone 200966 skp 7952917 skp Escherichia coli BW2952 periplasmic chaperone YP_002925372.1 200481 D 595496 CDS YP_002925373.1 238899577 7954487 200970..201995 1 NC_012759.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 201995 lpxD 7954487 lpxD Escherichia coli BW2952 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002925373.1 200970 D 595496 CDS YP_002925374.1 238899578 7956226 202100..202555 1 NC_012759.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 202555 fabZ 7956226 fabZ Escherichia coli BW2952 (3R)-hydroxymyristoyl-ACP dehydratase YP_002925374.1 202100 D 595496 CDS YP_002925375.1 238899579 7952214 202559..203347 1 NC_012759.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 203347 lpxA 7952214 lpxA Escherichia coli BW2952 UDP-N-acetylglucosamine acyltransferase YP_002925375.1 202559 D 595496 CDS YP_002925376.1 238899580 7956240 203347..204495 1 NC_012759.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 204495 lpxB 7956240 lpxB Escherichia coli BW2952 lipid-A-disaccharide synthase YP_002925376.1 203347 D 595496 CDS YP_002925377.1 238899581 7956120 204492..205088 1 NC_012759.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 205088 rnhB 7956120 rnhB Escherichia coli BW2952 ribonuclease HII YP_002925377.1 204492 D 595496 CDS YP_002925378.1 238899582 7955960 205125..208607 1 NC_012759.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 208607 dnaE 7955960 dnaE Escherichia coli BW2952 DNA polymerase III subunit alpha YP_002925378.1 205125 D 595496 CDS YP_002925379.1 238899583 7953318 208620..209579 1 NC_012759.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 209579 accA 7953318 accA Escherichia coli BW2952 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002925379.1 208620 D 595496 CDS YP_002925380.1 238899584 7952401 209678..211819 1 NC_012759.1 MG1655 equivalent: b0186; lysine decarboxylase 2, constitutive 211819 ldcC 7952401 ldcC Escherichia coli BW2952 lysine decarboxylase 2, constitutive YP_002925380.1 209678 D 595496 CDS YP_002925381.1 238899585 7954181 211876..212265 1 NC_012759.1 MG1655 equivalent: b0187; hypothetical protein 212265 yaeR 7954181 yaeR Escherichia coli BW2952 hypothetical protein YP_002925381.1 211876 D 595496 CDS YP_002925382.1 238899586 7955126 212330..213628 1 NC_012759.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 213628 tilS 7955126 tilS Escherichia coli BW2952 tRNA(Ile)-lysidine synthetase YP_002925382.1 212330 D 595496 CDS YP_002925383.1 238899587 7956203 complement(213677..213931) 1 NC_012759.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 213931 rof 7956203 rof Escherichia coli BW2952 Rho-binding antiterminator YP_002925383.1 213677 R 595496 CDS YP_002925384.1 238899588 7954279 complement(213924..214124) 1 NC_012759.1 MG1655 equivalent: b4406; hypothetical protein 214124 yaeP 7954279 yaeP Escherichia coli BW2952 hypothetical protein YP_002925384.1 213924 R 595496 CDS YP_002925385.1 238899589 7952908 214290..214835 1 NC_012759.1 MG1655 equivalent: b0190; hypothetical protein 214835 yaeQ 7952908 yaeQ Escherichia coli BW2952 hypothetical protein YP_002925385.1 214290 D 595496 CDS YP_002925386.1 238899590 7952918 214832..215254 1 NC_012759.1 MG1655 equivalent: b0191; peptidyl-tRNA hydrolase domain-containing protein 215254 yaeJ 7952918 yaeJ Escherichia coli BW2952 peptidyl-tRNA hydrolase domain-containing protein YP_002925386.1 214832 D 595496 CDS YP_002925387.1 238899591 7952919 215268..215978 1 NC_012759.1 MG1655 equivalent: b0192; lipoprotein involved with copper homeostasis and adhesion 215978 nlpE 7952919 nlpE Escherichia coli BW2952 lipoprotein involved with copper homeostasis and adhesion YP_002925387.1 215268 D 595496 CDS YP_002925388.1 238899592 7954157 complement(216178..217002) 1 NC_012759.1 MG1655 equivalent: b0193; hypothetical protein 217002 yaeF 7954157 yaeF Escherichia coli BW2952 hypothetical protein YP_002925388.1 216178 R 595496 CDS YP_002925389.1 238899593 7955102 complement(217056..218774) 1 NC_012759.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 218774 proS 7955102 proS Escherichia coli BW2952 prolyl-tRNA synthetase YP_002925389.1 217056 R 595496 CDS YP_002925390.1 238899594 7955772 complement(218886..219593) 1 NC_012759.1 MG1655 equivalent: b0195; hypothetical protein 219593 yaeB 7955772 yaeB Escherichia coli BW2952 hypothetical protein YP_002925390.1 218886 R 595496 CDS YP_002925391.1 238899595 7952758 complement(219590..219994) 1 NC_012759.1 MG1655 equivalent: b0196; outer membrane lipoprotein 219994 rcsF 7952758 rcsF Escherichia coli BW2952 outer membrane lipoprotein YP_002925391.1 219590 R 595496 CDS YP_002925392.1 238899596 7955217 complement(220112..220927) 1 NC_012759.1 MG1655 equivalent: b0197; DL-methionine transporter substrate-binding subunit 220927 metQ 7955217 metQ Escherichia coli BW2952 DL-methionine transporter substrate-binding subunit YP_002925392.1 220112 R 595496 CDS YP_002925393.1 238899597 7953273 complement(220967..221620) 1 NC_012759.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 221620 metI 7953273 metI Escherichia coli BW2952 DL-methionine transporter permease YP_002925393.1 220967 R 595496 CDS YP_002925394.1 238899598 7953274 complement(221613..222644) 1 NC_012759.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 222644 metN 7953274 metN Escherichia coli BW2952 DL-methionine transporter ATP-binding subunit YP_002925394.1 221613 R 595496 CDS YP_002925395.1 238899599 7953275 222832..223407 1 NC_012759.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 223407 gmhB 7953275 gmhB Escherichia coli BW2952 D,D-heptose 1,7-bisphosphate phosphatase YP_002925395.1 222832 D 595496 CDS YP_002925396.1 238899600 7952117 229166..229969 1 NC_012759.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 229969 dkgB 7952117 dkgB Escherichia coli BW2952 2,5-diketo-D-gluconate reductase B YP_002925396.1 229166 D 595496 CDS YP_002925397.1 238899601 7952239 complement(229966..230880) 1 NC_012759.1 MG1655 equivalent: b0208; putative DNA-binding transcriptional regulator 230880 yafC 7952239 yafC Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925397.1 229966 R 595496 CDS YP_002925398.1 238899602 7954745 231121..231921 1 NC_012759.1 MG1655 equivalent: b0209; hypothetical protein 231921 yafD 7954745 yafD Escherichia coli BW2952 hypothetical protein YP_002925398.1 231121 D 595496 CDS YP_002925399.1 238899603 7952920 231925..232548 1 NC_012759.1 MG1655 equivalent: b0210; putative S-adenosyl-L-methionine-dependent methyltransferase 232548 yafE 7952920 yafE Escherichia coli BW2952 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002925399.1 231925 D 595496 CDS YP_002925400.1 238899604 7955576 complement(232596..233954) 1 NC_012759.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 233954 mltD 7955576 mltD Escherichia coli BW2952 membrane-bound lytic murein transglycosylase D YP_002925400.1 232596 R 595496 CDS YP_002925401.1 238899605 7955142 complement(234026..234781) 1 NC_012759.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 234781 gloB 7955142 gloB Escherichia coli BW2952 hydroxyacylglutathione hydrolase YP_002925401.1 234026 R 595496 CDS YP_002925402.1 238899606 7954980 234815..235537 1 NC_012759.1 MG1655 equivalent: b0213; putative S-adenosyl-L-methionine-dependent methyltransferase 235537 yafS 7954980 yafS Escherichia coli BW2952 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002925402.1 234815 D 595496 CDS YP_002925403.1 238899607 7955577 complement(235534..236001) 1 NC_012759.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 236001 rnhA 7955577 rnhA Escherichia coli BW2952 ribonuclease H YP_002925403.1 235534 R 595496 CDS YP_002925404.1 238899608 7955959 236066..236797 1 NC_012759.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 236797 dnaQ 7955959 dnaQ Escherichia coli BW2952 DNA polymerase III subunit epsilon YP_002925404.1 236066 D 595496 CDS YP_002925405.1 238899609 7952118 237334..238119 1 NC_012759.1 MG1655 equivalent: b0217; putative aminopeptidase 238119 yafT 7952118 yafT Escherichia coli BW2952 putative aminopeptidase YP_002925405.1 237334 D 595496 CDS YP_002925406.1 238899610 7954646 complement(238256..238735) 1 NC_012759.1 MG1655 equivalent: b4586; hypothetical protein 238735 ykfM 7954646 ykfM Escherichia coli BW2952 hypothetical protein YP_002925406.1 238256 R 595496 CDS YP_002925407.1 238899611 7953984 complement(239418..240188) 1 NC_012759.1 MG1655 equivalent: b0219; hypothetical protein 240188 yafV 7953984 yafV Escherichia coli BW2952 hypothetical protein YP_002925407.1 239418 R 595496 CDS YP_002925408.1 238899612 7954695 240342..240815 1 NC_012759.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 240815 ivy 7954695 ivy Escherichia coli BW2952 C-lysozyme inhibitor YP_002925408.1 240342 D 595496 CDS YP_002925409.1 238899613 7953995 complement(240858..243302) 1 NC_012759.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 243302 fadE 7953995 fadE Escherichia coli BW2952 acyl-CoA dehydrogenase YP_002925409.1 240858 R 595496 CDS YP_002925410.1 238899614 7952414 243542..244120 1 NC_012759.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 244120 gmhA 7952414 gmhA Escherichia coli BW2952 phosphoheptose isomerase YP_002925410.1 243542 D 595496 CDS YP_002925411.1 238899615 7953496 244326..245093 1 NC_012759.1 MG1655 equivalent: b0223; putative amidotransfease 245093 yafJ 7953496 yafJ Escherichia coli BW2952 putative amidotransfease YP_002925411.1 244326 D 595496 CDS YP_002925412.1 238899616 7954638 complement(245064..245804) 1 NC_012759.1 MG1655 equivalent: b0224; hypothetical protein 245804 yafK 7954638 yafK Escherichia coli BW2952 hypothetical protein YP_002925412.1 245064 R 595496 CDS YP_002925413.1 238899617 7952759 complement(245960..246238) 1 NC_012759.1 MG1655 equivalent: b0225; putative toxin of the YafQ-DinJ toxin-antitoxin system 246238 yafQ 7952759 yafQ Escherichia coli BW2952 putative toxin of the YafQ-DinJ toxin-antitoxin system YP_002925413.1 245960 R 595496 CDS YP_002925414.1 238899618 7955627 complement(246241..246501) 1 NC_012759.1 MG1655 equivalent: b0226; putative antitoxin of YafQ-DinJ toxin-antitoxin system 246501 dinJ 7955627 dinJ Escherichia coli BW2952 putative antitoxin of YafQ-DinJ toxin-antitoxin system YP_002925414.1 246241 R 595496 CDS YP_002925415.1 238899619 7954656 246711..247460 1 NC_012759.1 MG1655 equivalent: b0227; putative lipoprotein and C40 family peptidase 247460 yafL 7954656 yafL Escherichia coli BW2952 putative lipoprotein and C40 family peptidase YP_002925415.1 246711 D 595496 CDS YP_002925416.1 238899620 7955120 247636..248133 1 NC_012759.1 MG1655 equivalent: b0228; hypothetical protein 248133 yafM 7955120 yafM Escherichia coli BW2952 hypothetical protein YP_002925416.1 247636 D 595496 CDS YP_002925417.1 238899621 7952921 250897..251952 1 NC_012759.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 251952 dinB 7952921 dinB Escherichia coli BW2952 DNA polymerase IV YP_002925417.1 250897 D 595496 CDS YP_002925418.1 238899622 7953327 252004..252297 1 NC_012759.1 MG1655 equivalent: b0232; putative antitoxin of the YafO-YafN toxin-antitoxin system 252297 yafN 7953327 yafN Escherichia coli BW2952 putative antitoxin of the YafO-YafN toxin-antitoxin system YP_002925418.1 252004 D 595496 CDS YP_002925419.1 238899623 7954655 252300..252698 1 NC_012759.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; putative toxin YafO 252698 yafO 7954655 yafO Escherichia coli BW2952 putative toxin YafO YP_002925419.1 252300 D 595496 CDS YP_002925420.1 238899624 7955626 252708..253160 1 NC_012759.1 MG1655 equivalent: b0234; hypothetical protein 253160 yafP 7955626 yafP Escherichia coli BW2952 hypothetical protein YP_002925420.1 252708 D 595496 CDS YP_002925421.1 238899625 7954620 complement(254258..255715) 1 NC_012759.1 MG1655 equivalent: b0237; aminoacyl-histidine dipeptidase 255715 pepD 7954620 pepD Escherichia coli BW2952 aminoacyl-histidine dipeptidase YP_002925421.1 254258 R 595496 CDS YP_002925422.1 238899626 7952464 255976..256434 1 NC_012759.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 256434 gpt 7952464 gpt Escherichia coli BW2952 xanthine-guanine phosphoribosyltransferase YP_002925422.1 255976 D 595496 CDS YP_002925423.1 238899627 7953885 256526..257770 1 NC_012759.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 257770 frsA 7953885 frsA Escherichia coli BW2952 fermentation/respiration switch protein YP_002925423.1 256526 D 595496 CDS YP_002925424.1 238899628 7953957 257828..258229 1 NC_012759.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 258229 crl 7953957 crl Escherichia coli BW2952 DNA-binding transcriptional regulator Crl YP_002925424.1 257828 D 595496 CDS YP_002925425.1 238899629 7953442 complement(258268..259323) 1 NC_012759.1 MG1655 equivalent: b0241; outer membrane phosphoporin protein E 259323 phoE 7953442 phoE Escherichia coli BW2952 outer membrane phosphoporin protein E YP_002925425.1 258268 R 595496 CDS YP_002925426.1 238899630 7954442 259611..260714 1 NC_012759.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 260714 proB 7954442 proB Escherichia coli BW2952 gamma-glutamyl kinase YP_002925426.1 259611 D 595496 CDS YP_002925427.1 238899631 7953768 260726..261979 1 NC_012759.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 261979 proA 7953768 proA Escherichia coli BW2952 gamma-glutamyl phosphate reductase YP_002925427.1 260726 D 595496 CDS YP_002925428.1 238899632 7952119 complement(262551..262892) 1 NC_012759.1 MG1655 equivalent: b0245; CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system 262892 ykfI 7952119 ykfI Escherichia coli BW2952 CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system YP_002925428.1 262551 R 595496 CDS YP_002925429.1 238899633 7953139 complement(262913..263230) 1 NC_012759.1 MG1655 equivalent: b0246; CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system 263230 yafW 7953139 yafW Escherichia coli BW2952 CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system YP_002925429.1 262913 R 595496 CDS YP_002925430.1 238899634 7953130 complement(263249..263470) 1 NC_012759.1 MG1655 equivalent: b4504; hypothetical protein 263470 ykfH 7953130 ykfH Escherichia coli BW2952 hypothetical protein YP_002925430.1 263249 R 595496 CDS YP_002925431.1 238899635 7955432 complement(263479..263955) 1 NC_012759.1 MG1655 equivalent: b0247; CP4-6 prophage; putative DNA repair protein 263955 ykfG 7955432 ykfG Escherichia coli BW2952 CP4-6 prophage; putative DNA repair protein YP_002925431.1 263479 R 595496 CDS YP_002925432.1 238899636 7953132 complement(263971..264429) 1 NC_012759.1 MG1655 equivalent: b0248; CP4-6 prophage protein 264429 yafX 7953132 yafX Escherichia coli BW2952 CP4-6 prophage protein YP_002925432.1 263971 R 595496 CDS YP_002925433.1 238899637 7953136 complement(264527..264766) 1 NC_012759.1 MG1655 equivalent: b0249; CP4-6 prophage protein 264766 ykfF 7953136 ykfF Escherichia coli BW2952 CP4-6 prophage protein YP_002925433.1 264527 R 595496 CDS YP_002925434.1 238899638 7953137 complement(264843..265310) 1 NC_012759.1 MG1655 equivalent: b0250; CP4-6 prophage protein 265310 ykfB 7953137 ykfB Escherichia coli BW2952 CP4-6 prophage protein YP_002925434.1 264843 R 595496 CDS YP_002925435.1 238899639 7953138 complement(265333..265776) 1 NC_012759.1 MG1655 equivalent: b0251; CP4-6 prophage; putative DNA-binding transcriptional regulator 265776 yafY 7953138 yafY Escherichia coli BW2952 CP4-6 prophage; putative DNA-binding transcriptional regulator YP_002925435.1 265333 R 595496 CDS YP_002925436.1 238899640 7953133 complement(266407..267228) 1 NC_012759.1 MG1655 equivalent: b0252; CP4-6 prophage protein 267228 yafZ 7953133 yafZ Escherichia coli BW2952 CP4-6 prophage protein YP_002925436.1 266407 R 595496 CDS YP_002925437.1 238899641 7953131 complement(267320..268183) 1 NC_012759.1 MG1655 equivalent: b0253; CP4-6 prophage; putative GTP-binding protein 268183 ykfA 7953131 ykfA Escherichia coli BW2952 CP4-6 prophage; putative GTP-binding protein YP_002925437.1 267320 R 595496 CDS YP_002925438.1 238899642 7953135 complement(268512..269405) 1 NC_012759.1 MG1655 equivalent: b0254; CP4-6 prophage; putative DNA-binding transcriptional regulator 269405 perR 7953135 perR Escherichia coli BW2952 CP4-6 prophage; putative DNA-binding transcriptional regulator YP_002925438.1 268512 R 595496 CDS YP_002925439.1 238899643 7953134 269826..270977 1 NC_012759.1 MG1655 equivalent: b0256; KpLE2 phage-like element; IS30 transposase 270977 insI 7953134 insI Escherichia coli BW2952 KpLE2 phage-like element; IS30 transposase YP_002925439.1 269826 D 595496 CDS YP_002925440.1 238899644 7954084 complement(273324..274340) 1 NC_012759.1 MG1655 equivalent: b0259; IS5 transposase and trans-activator 274340 insH 7954084 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002925440.1 273324 R 595496 CDS YP_002925441.1 238899645 7954036 274524..274907 1 NC_012759.1 MG1655 equivalent: b0350; 2-keto-4-pentenoate hydratase 274907 mhpD 7954036 mhpD Escherichia coli BW2952 2-keto-4-pentenoate hydratase YP_002925441.1 274524 D 595496 CDS YP_002925442.1 238899646 7952261 274904..275854 1 NC_012759.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 275854 mhpF 7952261 mhpF Escherichia coli BW2952 acetaldehyde dehydrogenase YP_002925442.1 274904 D 595496 CDS YP_002925443.1 238899647 7952387 275851..276864 1 NC_012759.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 276864 mhpE 7952387 mhpE Escherichia coli BW2952 4-hydroxy-2-ketovalerate aldolase YP_002925443.1 275851 D 595496 CDS YP_002925444.1 238899648 7952334 277442..278653 1 NC_012759.1 MG1655 equivalent: b0353; putative 3-hydroxyphenylpropionic transporter MhpT 278653 mhpT 7952334 mhpT Escherichia coli BW2952 putative 3-hydroxyphenylpropionic transporter MhpT YP_002925444.1 277442 D 595496 CDS YP_002925445.1 238899649 7954588 278755..279294 1 NC_012759.1 MG1655 equivalent: b0354; nucleoprotein/polynucleotide-associated enzyme 279294 yaiL 7954588 yaiL Escherichia coli BW2952 nucleoprotein/polynucleotide-associated enzyme YP_002925445.1 278755 D 595496 CDS YP_002925446.1 238899650 7954408 complement(279518..280351) 1 NC_012759.1 MG1655 equivalent: b0355; putative esterase 280351 frmB 7954408 frmB Escherichia coli BW2952 putative esterase YP_002925446.1 279518 R 595496 CDS YP_002925447.1 238899651 7954861 complement(280445..281554) 1 NC_012759.1 MG1655 equivalent: b0356; alcohol dehydrogenase 281554 frmA 7954861 frmA Escherichia coli BW2952 alcohol dehydrogenase YP_002925447.1 280445 R 595496 CDS YP_002925448.1 238899652 7952441 complement(281589..281864) 1 NC_012759.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 281864 frmR 7952441 frmR Escherichia coli BW2952 regulator protein FrmR YP_002925448.1 281589 R 595496 CDS YP_002925449.1 238899653 7955926 complement(282052..282825) 1 NC_012759.1 MG1655 equivalent: b0358; hypothetical protein 282825 yaiO 7955926 yaiO Escherichia coli BW2952 hypothetical protein YP_002925449.1 282052 R 595496 CDS YP_002925450.1 238899654 7955336 283334..283699 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 283699 insC 7955336 insC Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002925450.1 283334 D 595496 CDS YP_002925451.1 238899655 7954074 283657..284562 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 284562 insD 7954074 insD Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002925451.1 283657 D 595496 CDS YP_002925452.1 238899656 7954080 complement(284722..285918) 1 NC_012759.1 MG1655 equivalent: b0363; putative glucosyltransferase 285918 yaiP 7954080 yaiP Escherichia coli BW2952 putative glucosyltransferase YP_002925452.1 284722 R 595496 CDS YP_002925453.1 238899657 7954920 complement(286042..286599) 1 NC_012759.1 MG1655 equivalent: b0364; hypothetical protein 286599 yaiS 7954920 yaiS Escherichia coli BW2952 hypothetical protein YP_002925453.1 286042 R 595496 CDS YP_002925454.1 238899658 7952760 287215..288177 1 NC_012759.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 288177 tauA 7952760 tauA Escherichia coli BW2952 taurine transporter substrate binding subunit YP_002925454.1 287215 D 595496 CDS YP_002925455.1 238899659 7956114 288190..288957 1 NC_012759.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 288957 tauB 7956114 tauB Escherichia coli BW2952 taurine transporter ATP-binding subunit YP_002925455.1 288190 D 595496 CDS YP_002925456.1 238899660 7956115 288954..289781 1 NC_012759.1 MG1655 equivalent: b0367; taurine transporter subunit 289781 tauC 7956115 tauC Escherichia coli BW2952 taurine transporter subunit YP_002925456.1 288954 D 595496 CDS YP_002925457.1 238899661 7956116 289778..290629 1 NC_012759.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 290629 tauD 7956116 tauD Escherichia coli BW2952 taurine dioxygenase YP_002925457.1 289778 D 595496 CDS YP_002925458.1 238899662 7956113 complement(290736..291710) 1 NC_012759.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 291710 hemB 7956113 hemB Escherichia coli BW2952 delta-aminolevulinic acid dehydratase YP_002925458.1 290736 R 595496 CDS YP_002925459.1 238899663 7954570 complement(293722..294588) 1 NC_012759.1 MG1655 equivalent: b0372; IS3 element protein InsF 294588 insF 7954570 insF Escherichia coli BW2952 IS3 element protein InsF YP_002925459.1 293722 R 595496 CDS YP_002925460.1 238899664 7954032 complement(294585..294893) 1 NC_012759.1 MG1655 equivalent: b0373; IS3 element protein InsE 294893 insE 7954032 insE Escherichia coli BW2952 IS3 element protein InsE YP_002925460.1 294585 R 595496 CDS YP_002925461.1 238899665 7954028 296444..297112 1 NC_012759.1 MG1655 equivalent: b0375; putative DNA-binding transcriptional regulator 297112 yaiV 7954028 yaiV Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925461.1 296444 D 595496 CDS YP_002925462.1 238899666 7954789 complement(297113..298270) 1 NC_012759.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 298270 ampH 7954789 ampH Escherichia coli BW2952 beta-lactam binding protein AmpH YP_002925462.1 297113 R 595496 CDS YP_002925463.1 238899667 7952552 298622..299842 1 NC_012759.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 299842 sbmA 7952552 sbmA Escherichia coli BW2952 transporter YP_002925463.1 298622 D 595496 CDS YP_002925464.1 238899668 7955678 299855..300949 1 NC_012759.1 MG1655 equivalent: b0378; putative DNA-binding transcriptional regulator 300949 yaiW 7955678 yaiW Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925464.1 299855 D 595496 CDS YP_002925465.1 238899669 7954790 complement(301008..301316) 1 NC_012759.1 MG1655 equivalent: b0379; putative inner membrane protein 301316 yaiY 7954790 yaiY Escherichia coli BW2952 putative inner membrane protein YP_002925465.1 301008 R 595496 CDS YP_002925466.1 238899670 7954985 301576..301788 1 NC_012759.1 MG1655 equivalent: b0380; putative inner membrane protein 301788 yaiZ 7954985 yaiZ Escherichia coli BW2952 putative inner membrane protein YP_002925466.1 301576 D 595496 CDS YP_002925467.1 238899671 7955023 complement(301812..302906) 1 NC_012759.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 302906 ddl 7955023 ddl Escherichia coli BW2952 D-alanyl-alanine synthetase A YP_002925467.1 301812 R 595496 CDS YP_002925468.1 238899672 7953216 303369..303629 1 NC_012759.1 MG1655 equivalent: b0382; hypothetical protein 303629 iraP 7953216 iraP Escherichia coli BW2952 hypothetical protein YP_002925468.1 303369 D 595496 CDS YP_002925469.1 238899673 7955440 303730..305145 1 NC_012759.1 MG1655 equivalent: b0383; alkaline phosphatase 305145 phoA 7955440 phoA Escherichia coli BW2952 alkaline phosphatase YP_002925469.1 303730 D 595496 CDS YP_002925470.1 238899674 7952540 305264..305584 1 NC_012759.1 MG1655 equivalent: b0384; hypothetical protein 305584 psiF 7952540 psiF Escherichia coli BW2952 hypothetical protein YP_002925470.1 305264 D 595496 CDS YP_002925471.1 238899675 7952922 305686..306801 1 NC_012759.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 306801 adrA 7952922 adrA Escherichia coli BW2952 diguanylate cyclase AdrA YP_002925471.1 305686 D 595496 CDS YP_002925472.1 238899676 7954726 complement(306818..307627) 1 NC_012759.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 307627 proC 7954726 proC Escherichia coli BW2952 pyrroline-5-carboxylate reductase YP_002925472.1 306818 R 595496 CDS YP_002925473.1 238899677 7955843 307747..308205 1 NC_012759.1 MG1655 equivalent: b0387; hypothetical protein 308205 yaiI 7955843 yaiI Escherichia coli BW2952 hypothetical protein YP_002925473.1 307747 D 595496 CDS YP_002925474.1 238899678 7952923 308388..308912 1 NC_012759.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 308912 aroL 7952923 aroL Escherichia coli BW2952 shikimate kinase YP_002925474.1 308388 D 595496 CDS YP_002925475.1 238899679 7956038 308962..309153 1 NC_012759.1 MG1655 equivalent: b0389; hypothetical protein 309153 yaiA 7956038 yaiA Escherichia coli BW2952 hypothetical protein YP_002925475.1 308962 D 595496 CDS YP_002925476.1 238899680 7955441 309411..310088 1 NC_012759.1 MG1655 equivalent: b0390; hypothetical protein 310088 aroM 7955441 aroM Escherichia coli BW2952 hypothetical protein YP_002925476.1 309411 D 595496 CDS YP_002925477.1 238899681 7952924 310160..310444 1 NC_012759.1 MG1655 equivalent: b0391; hypothetical protein 310444 yaiE 7952924 yaiE Escherichia coli BW2952 hypothetical protein YP_002925477.1 310160 D 595496 CDS YP_002925478.1 238899682 7952925 complement(311091..312002) 1 NC_012759.1 Required for efficient pilin antigenic variation; recombination associated protein 312002 rdgC 7952925 rdgC Escherichia coli BW2952 recombination associated protein YP_002925478.1 311091 R 595496 CDS YP_002925479.1 238899683 7953341 312127..313035 1 NC_012759.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 313035 mak 7953341 mak Escherichia coli BW2952 fructokinase YP_002925479.1 312127 D 595496 CDS YP_002925480.1 238899684 7954212 complement(313280..314464) 1 NC_012759.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 314464 araJ 7954212 araJ Escherichia coli BW2952 MFS transport protein AraJ YP_002925480.1 313280 R 595496 CDS YP_002925481.1 238899685 7955648 complement(314590..317736) 1 NC_012759.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 317736 sbcC 7955648 sbcC Escherichia coli BW2952 exonuclease subunit SbcC YP_002925481.1 314590 R 595496 CDS YP_002925482.1 238899686 7953546 complement(317733..318935) 1 NC_012759.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 318935 sbcD 7953546 sbcD Escherichia coli BW2952 exonuclease subunit SbcD YP_002925482.1 317733 R 595496 CDS YP_002925483.1 238899687 7953547 319125..319814 1 NC_012759.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 319814 phoB 7953547 phoB Escherichia coli BW2952 transcriptional regulator PhoB YP_002925483.1 319125 D 595496 CDS YP_002925484.1 238899688 7953358 319872..321167 1 NC_012759.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 321167 phoR 7953358 phoR Escherichia coli BW2952 phosphate regulon sensor protein YP_002925484.1 319872 D 595496 CDS YP_002925485.1 238899689 7956023 321574..322893 1 NC_012759.1 MG1655 equivalent: b0401; putative branched chain amino acid transporter (LIV-II) 322893 brnQ 7956023 brnQ Escherichia coli BW2952 putative branched chain amino acid transporter (LIV-II) YP_002925485.1 321574 D 595496 CDS YP_002925486.1 238899690 7954671 322969..324342 1 NC_012759.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 324342 proY 7954671 proY Escherichia coli BW2952 putative proline-specific permease YP_002925486.1 322969 D 595496 CDS YP_002925487.1 238899691 7954703 324498..326315 1 NC_012759.1 MG1655 equivalent: b0403; maltodextrin glucosidase 326315 malZ 7954703 malZ Escherichia coli BW2952 maltodextrin glucosidase YP_002925487.1 324498 D 595496 CDS YP_002925488.1 238899692 7954203 complement(326320..326901) 1 NC_012759.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 326901 acpH 7954203 acpH Escherichia coli BW2952 acyl carrier protein phosphodiesterase YP_002925488.1 326320 R 595496 CDS YP_002925489.1 238899693 7952761 326994..328064 1 NC_012759.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 328064 queA 7952761 queA Escherichia coli BW2952 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002925489.1 326994 D 595496 CDS YP_002925490.1 238899694 7955999 328120..329247 1 NC_012759.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 329247 tgt 7955999 tgt Escherichia coli BW2952 queuine tRNA-ribosyltransferase YP_002925490.1 328120 D 595496 CDS YP_002925491.1 238899695 7956207 329270..329602 1 NC_012759.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 329602 yajC 7956207 yajC Escherichia coli BW2952 preprotein translocase subunit YajC YP_002925491.1 329270 D 595496 CDS YP_002925492.1 238899696 7956003 329630..331477 1 NC_012759.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 331477 secD 7956003 secD Escherichia coli BW2952 preprotein translocase subunit SecD YP_002925492.1 329630 D 595496 CDS YP_002925493.1 238899697 7956004 331488..332459 1 NC_012759.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 332459 secF 7956004 secF Escherichia coli BW2952 preprotein translocase subunit SecF YP_002925493.1 331488 D 595496 CDS YP_002925494.1 238899698 7956005 332588..332935 1 NC_012759.1 MG1655 equivalent: b0410; hypothetical protein 332935 yajD 7956005 yajD Escherichia coli BW2952 hypothetical protein YP_002925494.1 332588 D 595496 CDS YP_002925495.1 238899699 7952926 complement(333112..333996) 1 NC_012759.1 MG1655 equivalent: b0411; nucleoside channel phage T6/colicin K receptor 333996 tsx 7952926 tsx Escherichia coli BW2952 nucleoside channel phage T6/colicin K receptor YP_002925495.1 333112 R 595496 CDS YP_002925496.1 238899700 7954410 complement(334295..334834) 1 NC_012759.1 MG1655 equivalent: b0412; hypothetical protein 334834 yajI 7954410 yajI Escherichia coli BW2952 hypothetical protein YP_002925496.1 334295 R 595496 CDS YP_002925497.1 238899701 7955103 334985..335434 1 NC_012759.1 MG1655 equivalent: b0413; transcriptional regulator NrdR 335434 nrdR 7955103 nrdR Escherichia coli BW2952 transcriptional regulator NrdR YP_002925497.1 334985 D 595496 CDS YP_002925498.1 238899702 7952927 335438..336541 1 NC_012759.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 336541 ribD 7952927 ribD Escherichia coli BW2952 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_002925498.1 335438 D 595496 CDS YP_002925499.1 238899703 7953672 336630..337100 1 NC_012759.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 337100 ribH 7953672 ribH Escherichia coli BW2952 6,7-dimethyl-8-ribityllumazine synthase YP_002925499.1 336630 D 595496 CDS YP_002925500.1 238899704 7955953 337120..337539 1 NC_012759.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 337539 nusB 7955953 nusB Escherichia coli BW2952 transcription antitermination protein NusB YP_002925500.1 337120 D 595496 CDS YP_002925501.1 238899705 7956166 337617..338594 1 NC_012759.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 338594 thiL 7956166 thiL Escherichia coli BW2952 thiamine monophosphate kinase YP_002925501.1 337617 D 595496 CDS YP_002925502.1 238899706 7956132 338572..339090 1 NC_012759.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 339090 pgpA 7956132 pgpA Escherichia coli BW2952 phosphatidylglycerophosphatase A YP_002925502.1 338572 D 595496 CDS YP_002925503.1 238899707 7954522 complement(339144..340118) 1 NC_012759.1 MG1655 equivalent: b0419; 2-carboxybenzaldehyde reductase 340118 yajO 7954522 yajO Escherichia coli BW2952 2-carboxybenzaldehyde reductase YP_002925503.1 339144 R 595496 CDS YP_002925504.1 238899708 7952253 complement(340298..342160) 1 NC_012759.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 342160 dxs 7952253 dxs Escherichia coli BW2952 1-deoxy-D-xylulose-5-phosphate synthase YP_002925504.1 340298 R 595496 CDS YP_002925505.1 238899709 7952228 complement(342185..343084) 1 NC_012759.1 MG1655 equivalent: b0421; geranyltranstransferase 343084 ispA 7952228 ispA Escherichia coli BW2952 geranyltranstransferase YP_002925505.1 342185 R 595496 CDS YP_002925506.1 238899710 7953787 complement(343084..343326) 1 NC_012759.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 343326 xseB 7953787 xseB Escherichia coli BW2952 exodeoxyribonuclease VII small subunit YP_002925506.1 343084 R 595496 CDS YP_002925507.1 238899711 7953544 343532..344980 1 NC_012759.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 344980 thiI 7953544 thiI Escherichia coli BW2952 thiamine biosynthesis protein ThiI YP_002925507.1 343532 D 595496 CDS YP_002925508.1 238899712 7956097 complement(345034..345624) 1 NC_012759.1 MG1655 equivalent: b0424; DJ-1 family protein 345624 yajL 7956097 yajL Escherichia coli BW2952 DJ-1 family protein YP_002925508.1 345034 R 595496 CDS YP_002925509.1 238899713 7952762 complement(345587..346498) 1 NC_012759.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 346498 panE 7952762 panE Escherichia coli BW2952 2-dehydropantoate 2-reductase YP_002925509.1 345587 R 595496 CDS YP_002925510.1 238899714 7952255 346666..347157 1 NC_012759.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 347157 yajQ 7952255 yajQ Escherichia coli BW2952 putative nucleotide-binding protein YP_002925510.1 346666 D 595496 CDS YP_002925511.1 238899715 7955187 complement(347285..348649) 1 NC_012759.1 MG1655 equivalent: b0427; putative transporter 348649 yajR 7955187 yajR Escherichia coli BW2952 putative transporter YP_002925511.1 347285 R 595496 CDS YP_002925512.1 238899716 7955649 complement(348798..349688) 1 NC_012759.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 349688 cyoE 7955649 cyoE Escherichia coli BW2952 protoheme IX farnesyltransferase YP_002925512.1 348798 R 595496 CDS YP_002925513.1 238899717 7955815 complement(349700..350029) 1 NC_012759.1 MG1655 equivalent: b0429; cytochrome o ubiquinol oxidase subunit IV 350029 cyoD 7955815 cyoD Escherichia coli BW2952 cytochrome o ubiquinol oxidase subunit IV YP_002925513.1 349700 R 595496 CDS YP_002925514.1 238899718 7953199 complement(350029..350643) 1 NC_012759.1 MG1655 equivalent: b0430; cytochrome o ubiquinol oxidase subunit III 350643 cyoC 7953199 cyoC Escherichia coli BW2952 cytochrome o ubiquinol oxidase subunit III YP_002925514.1 350029 R 595496 CDS YP_002925515.1 238899719 7953198 complement(350633..352624) 1 NC_012759.1 MG1655 equivalent: b0431; cytochrome o ubiquinol oxidase subunit I 352624 cyoB 7953198 cyoB Escherichia coli BW2952 cytochrome o ubiquinol oxidase subunit I YP_002925515.1 350633 R 595496 CDS YP_002925516.1 238899720 7953196 complement(352646..353593) 1 NC_012759.1 MG1655 equivalent: b0432; cytochrome o ubiquinol oxidase subunit II 353593 cyoA 7953196 cyoA Escherichia coli BW2952 cytochrome o ubiquinol oxidase subunit II YP_002925516.1 352646 R 595496 CDS YP_002925517.1 238899721 7953197 complement(354053..355528) 1 NC_012759.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 355528 ampG 7953197 ampG Escherichia coli BW2952 muropeptide transporter YP_002925517.1 354053 R 595496 CDS YP_002925518.1 238899722 7954324 complement(355572..356150) 1 NC_012759.1 MG1655 equivalent: b0434; hypothetical protein 356150 yajG 7954324 yajG Escherichia coli BW2952 hypothetical protein YP_002925518.1 355572 R 595496 CDS YP_002925519.1 238899723 7955104 356455..356772 1 NC_012759.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 356772 bolA 7955104 bolA Escherichia coli BW2952 transcriptional regulator BolA YP_002925519.1 356455 D 595496 CDS YP_002925520.1 238899724 7955923 357116..358414 1 NC_012759.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 358414 tig 7955923 tig Escherichia coli BW2952 trigger factor YP_002925520.1 357116 D 595496 CDS YP_002925521.1 238899725 7954479 358660..359283 1 NC_012759.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 359283 clpP 7954479 clpP Escherichia coli BW2952 ATP-dependent Clp protease proteolytic subunit YP_002925521.1 358660 D 595496 CDS YP_002925522.1 238899726 7955814 359409..360683 1 NC_012759.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 360683 clpX 7955814 clpX Escherichia coli BW2952 ATP-dependent protease ATP-binding subunit ClpX YP_002925522.1 359409 D 595496 CDS YP_002925523.1 238899727 7952525 360871..363225 1 NC_012759.1 MG1655 equivalent: b0439; DNA-binding ATP-dependent protease La 363225 lon 7952525 lon Escherichia coli BW2952 DNA-binding ATP-dependent protease La YP_002925523.1 360871 D 595496 CDS YP_002925524.1 238899728 7953338 363434..363706 1 NC_012759.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 363706 hupB 7953338 hupB Escherichia coli BW2952 transcriptional regulator HU subunit beta YP_002925524.1 363434 D 595496 CDS YP_002925525.1 238899729 7953927 363898..365769 1 NC_012759.1 MG1655 equivalent: b0441; peptidyl-prolyl cis-trans isomerase 365769 ppiD 7953927 ppiD Escherichia coli BW2952 peptidyl-prolyl cis-trans isomerase YP_002925525.1 363898 D 595496 CDS YP_002925526.1 238899730 7954481 365920..366291 1 NC_012759.1 MG1655 equivalent: b0442; hypothetical protein 366291 ybaV 7954481 ybaV Escherichia coli BW2952 hypothetical protein YP_002925526.1 365920 D 595496 CDS YP_002925527.1 238899731 7952928 366385..366783 1 NC_012759.1 MG1655 equivalent: b0443; hypothetical protein 366783 ybaW 7952928 ybaW Escherichia coli BW2952 hypothetical protein YP_002925527.1 366385 D 595496 CDS YP_002925528.1 238899732 7952929 complement(366835..367530) 1 NC_012759.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 367530 queC 7952929 queC Escherichia coli BW2952 queuosine biosynthesis protein QueC YP_002925528.1 366835 R 595496 CDS YP_002925529.1 238899733 7954636 complement(367595..369295) 1 NC_012759.1 MG1655 equivalent: b0445; putative transporter subunit: periplasmic-binding component of ABC superfamily 369295 ybaE 7954636 ybaE Escherichia coli BW2952 putative transporter subunit: periplasmic-binding component of ABC superfamily YP_002925529.1 367595 R 595496 CDS YP_002925530.1 238899734 7955734 369395..370213 1 NC_012759.1 MG1655 equivalent: b0446; thiamin pyrimidine pyrophosphate hydrolase 370213 cof 7955734 cof Escherichia coli BW2952 thiamin pyrimidine pyrophosphate hydrolase YP_002925530.1 369395 D 595496 CDS YP_002925531.1 238899735 7956129 370366..370824 1 NC_012759.1 MG1655 equivalent: b0447; putative DNA-binding transcriptional regulator 370824 ybaO 7956129 ybaO Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925531.1 370366 D 595496 CDS YP_002925532.1 238899736 7954791 370854..372626 1 NC_012759.1 MG1655 equivalent: b0448; putative multidrug transporter membrane\ATP-binding components 372626 mdlA 7954791 mdlA Escherichia coli BW2952 putative multidrug transporter membrane\ATP-binding components YP_002925532.1 370854 D 595496 CDS YP_002925533.1 238899737 7953716 372619..374400 1 NC_012759.1 MG1655 equivalent: b0449; putative multidrug transporter membrane\ATP-binding components 374400 mdlB 7953716 mdlB Escherichia coli BW2952 putative multidrug transporter membrane\ATP-binding components YP_002925533.1 372619 D 595496 CDS YP_002925534.1 238899738 7953717 374581..374919 1 NC_012759.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 374919 glnK 7953717 glnK Escherichia coli BW2952 nitrogen regulatory protein P-II 2 YP_002925534.1 374581 D 595496 CDS YP_002925535.1 238899739 7954404 374949..376235 1 NC_012759.1 MG1655 equivalent: b0451; ammonium transporter 376235 amtB 7954404 amtB Escherichia coli BW2952 ammonium transporter YP_002925535.1 374949 D 595496 CDS YP_002925536.1 238899740 7952474 complement(376284..377144) 1 NC_012759.1 MG1655 equivalent: b0452; acyl-CoA thioesterase II 377144 tesB 7952474 tesB Escherichia coli BW2952 acyl-CoA thioesterase II YP_002925536.1 376284 R 595496 CDS YP_002925537.1 238899741 7952417 377362..377934 1 NC_012759.1 MG1655 equivalent: b0453; putative outer membrane lipoprotein 377934 ybaY 7952417 ybaY Escherichia coli BW2952 putative outer membrane lipoprotein YP_002925537.1 377362 D 595496 CDS YP_002925538.1 238899742 7955200 complement(377965..378354) 1 NC_012759.1 MG1655 equivalent: b0454; putative methyltransferase 378354 ybaZ 7955200 ybaZ Escherichia coli BW2952 putative methyltransferase YP_002925538.1 377965 R 595496 CDS YP_002925539.1 238899743 7952170 378655..379008 1 NC_012759.1 MG1655 equivalent: b0456; hypothetical protein 379008 ybaA 7952170 ybaA Escherichia coli BW2952 hypothetical protein YP_002925539.1 378655 D 595496 CDS YP_002925540.1 238899744 7952930 complement(379050..380600) 1 NC_012759.1 MG1655 equivalent: b0457; hypothetical protein 380600 ylaB 7952930 ylaB Escherichia coli BW2952 hypothetical protein YP_002925540.1 379050 R 595496 CDS YP_002925541.1 238899745 7952663 complement(380764..381234) 1 NC_012759.1 MG1655 equivalent: b0458; putative inner membrane protein 381234 ylaC 7952663 ylaC Escherichia coli BW2952 putative inner membrane protein YP_002925541.1 380764 R 595496 CDS YP_002925542.1 238899746 7954986 complement(381350..381901) 1 NC_012759.1 MG1655 equivalent: b0459; maltose O-acetyltransferase 381901 maa 7954986 maa Escherichia coli BW2952 maltose O-acetyltransferase YP_002925542.1 381350 R 595496 CDS YP_002925543.1 238899747 7954205 complement(382073..382291) 1 NC_012759.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 382291 hha 7954205 hha Escherichia coli BW2952 hemolysin expression-modulating protein YP_002925543.1 382073 R 595496 CDS YP_002925544.1 238899748 7954278 complement(382317..382691) 1 NC_012759.1 MG1655 equivalent: b0461; hypothetical protein 382691 ybaJ 7954278 ybaJ Escherichia coli BW2952 hypothetical protein YP_002925544.1 382317 R 595496 CDS YP_002925545.1 238899749 7955337 complement(383237..386386) 1 NC_012759.1 MG1655 equivalent: b0462; multidrug efflux system protein 386386 acrB 7955337 acrB Escherichia coli BW2952 multidrug efflux system protein YP_002925545.1 383237 R 595496 CDS YP_002925546.1 238899750 7954299 complement(386409..387602) 1 NC_012759.1 MG1655 equivalent: b0463; multidrug efflux system 387602 acrA 7954299 acrA Escherichia coli BW2952 multidrug efflux system YP_002925546.1 386409 R 595496 CDS YP_002925547.1 238899751 7954297 387744..388391 1 NC_012759.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 388391 acrR 7954297 acrR Escherichia coli BW2952 DNA-binding transcriptional repressor AcrR YP_002925547.1 387744 D 595496 CDS YP_002925548.1 238899752 7953461 388519..391881 1 NC_012759.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 391881 kefA 7953461 kefA Escherichia coli BW2952 potassium efflux protein KefA YP_002925548.1 388519 D 595496 CDS YP_002925549.1 238899753 7953666 complement(392093..392254) 1 NC_012759.1 MG1655 equivalent: b0466; hypothetical protein 392254 ybaM 7953666 ybaM Escherichia coli BW2952 hypothetical protein YP_002925549.1 392093 R 595496 CDS YP_002925550.1 238899754 7955338 complement(392268..392795) 1 NC_012759.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 392795 priC 7955338 priC Escherichia coli BW2952 primosomal replication protein N'' YP_002925550.1 392268 R 595496 CDS YP_002925551.1 238899755 7955765 392865..393242 1 NC_012759.1 MG1655 equivalent: b0468; hypothetical protein 393242 ybaN 7955765 ybaN Escherichia coli BW2952 hypothetical protein YP_002925551.1 392865 D 595496 CDS YP_002925552.1 238899756 7952699 393395..393946 1 NC_012759.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 393946 apt 7952699 apt Escherichia coli BW2952 adenine phosphoribosyltransferase YP_002925552.1 393395 D 595496 CDS YP_002925553.1 238899757 7952419 394075..396006 1 NC_012759.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 396006 dnaX 7952419 dnaX Escherichia coli BW2952 DNA polymerase III subunits gamma and tau YP_002925553.1 394075 D 595496 CDS YP_002925554.1 238899758 7953326 396059..396388 1 NC_012759.1 MG1655 equivalent: b0471; hypothetical protein 396388 ybaB 7953326 ybaB Escherichia coli BW2952 hypothetical protein YP_002925554.1 396059 D 595496 CDS YP_002925555.1 238899759 7952931 396388..396993 1 NC_012759.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 396993 recR 7952931 recR Escherichia coli BW2952 recombination protein RecR YP_002925555.1 396388 D 595496 CDS YP_002925556.1 238899760 7953775 397103..398977 1 NC_012759.1 molecular chaperone; heat shock protein 90 398977 htpG 7953775 htpG Escherichia coli BW2952 heat shock protein 90 YP_002925556.1 397103 D 595496 CDS YP_002925557.1 238899761 7954282 399158..399802 1 NC_012759.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 399802 adk 7954282 adk Escherichia coli BW2952 adenylate kinase YP_002925557.1 399158 D 595496 CDS YP_002925558.1 238899762 7952423 400038..401000 1 NC_012759.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 401000 hemH 7952423 hemH Escherichia coli BW2952 ferrochelatase YP_002925558.1 400038 D 595496 CDS YP_002925559.1 238899763 7953573 complement(400997..401956) 1 NC_012759.1 MG1655 equivalent: b0476; acetyl esterase 401956 aes 7953573 aes Escherichia coli BW2952 acetyl esterase YP_002925559.1 400997 R 595496 CDS YP_002925560.1 238899764 7952396 402108..403412 1 NC_012759.1 MG1655 equivalent: b0477; inosine/guanosine kinase 403412 gsk 7952396 gsk Escherichia coli BW2952 inosine/guanosine kinase YP_002925560.1 402108 D 595496 CDS YP_002925561.1 238899765 7954000 complement(403545..405221) 1 NC_012759.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein 405221 ybaL 7954000 ybaL Escherichia coli BW2952 putative cation:proton antiport protein YP_002925561.1 403545 R 595496 CDS YP_002925562.1 238899766 7955738 complement(405459..406679) 1 NC_012759.1 MG1655 equivalent: b0479; putative fosmidomycin efflux system 406679 fsr 7955738 fsr Escherichia coli BW2952 putative fosmidomycin efflux system YP_002925562.1 405459 R 595496 CDS YP_002925563.1 238899767 7954912 406897..408549 1 NC_012759.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 408549 ushA 7954912 ushA Escherichia coli BW2952 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_002925563.1 406897 D 595496 CDS YP_002925564.1 238899768 7952575 complement(408586..409065) 1 NC_012759.1 MG1655 equivalent: b0481; hypothetical protein 409065 ybaK 7952575 ybaK Escherichia coli BW2952 hypothetical protein YP_002925564.1 408586 R 595496 CDS YP_002925565.1 238899769 7952171 complement(409269..410063) 1 NC_012759.1 MG1655 equivalent: b0482; hypothetical protein 410063 ybaP 7952171 ybaP Escherichia coli BW2952 hypothetical protein YP_002925565.1 409269 R 595496 CDS YP_002925566.1 238899770 7952764 410201..410542 1 NC_012759.1 MG1655 equivalent: b0483; putative DNA-binding transcriptional regulator 410542 ybaQ 7952764 ybaQ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925566.1 410201 D 595496 CDS YP_002925567.1 238899771 7954792 complement(410858..413362) 1 NC_012759.1 MG1655 equivalent: b0484; copper exporting ATPase 413362 copA 7954792 copA Escherichia coli BW2952 copper exporting ATPase YP_002925567.1 410858 R 595496 CDS YP_002925568.1 238899772 7953097 413624..414556 1 NC_012759.1 catalyzes the formation of glutamate from glutamine; glutaminase 414556 ybaS 7953097 ybaS Escherichia coli BW2952 glutaminase YP_002925568.1 413624 D 595496 CDS YP_002925569.1 238899773 7954924 414559..415851 1 NC_012759.1 MG1655 equivalent: b0486; putative transporter 415851 ybaT 7954924 ybaT Escherichia coli BW2952 putative transporter YP_002925569.1 414559 D 595496 CDS YP_002925570.1 238899774 7955679 415976..416383 1 NC_012759.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 416383 cueR 7955679 cueR Escherichia coli BW2952 DNA-binding transcriptional regulator CueR YP_002925570.1 415976 D 595496 CDS YP_002925571.1 238899775 7953388 complement(416384..416842) 1 NC_012759.1 MG1655 equivalent: b0488; hypothetical protein 416842 ybbJ 7953388 ybbJ Escherichia coli BW2952 hypothetical protein YP_002925571.1 416384 R 595496 CDS YP_002925572.1 238899776 7952664 complement(416839..417756) 1 NC_012759.1 MG1655 equivalent: b0489; putative protease, membrane anchored 417756 qmcA 7952664 qmcA Escherichia coli BW2952 putative protease, membrane anchored YP_002925572.1 416839 R 595496 CDS YP_002925573.1 238899777 7955332 417902..418579 1 NC_012759.1 MG1655 equivalent: b0490; putative ABC transporter ATP-binding protein YbbL 418579 ybbL 7955332 ybbL Escherichia coli BW2952 putative ABC transporter ATP-binding protein YbbL YP_002925573.1 417902 D 595496 CDS YP_002925574.1 238899778 7955721 418566..419345 1 NC_012759.1 MG1655 equivalent: b0491; putative inner membrane protein 419345 ybbM 7955721 ybbM Escherichia coli BW2952 putative inner membrane protein YP_002925574.1 418566 D 595496 CDS YP_002925575.1 238899779 7955024 complement(419408..420262) 1 NC_012759.1 MG1655 equivalent: b0492; putative thioredoxin domain-containing protein 420262 ybbN 7955024 ybbN Escherichia coli BW2952 putative thioredoxin domain-containing protein YP_002925575.1 419408 R 595496 CDS YP_002925576.1 238899780 7955621 complement(420323..421132) 1 NC_012759.1 MG1655 equivalent: b0493; short chain dehydrogenase 421132 ybbO 7955621 ybbO Escherichia coli BW2952 short chain dehydrogenase YP_002925576.1 420323 R 595496 CDS YP_002925577.1 238899781 7955245 complement(421122..421748) 1 NC_012759.1 MG1655 equivalent: b0494; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 421748 tesA 7955245 tesA Escherichia coli BW2952 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_002925577.1 421122 R 595496 CDS YP_002925578.1 238899782 7954317 421716..422402 1 NC_012759.1 MG1655 equivalent: b0495; putative ABC transporter ATP-binding protein YbbA 422402 ybbA 7954317 ybbA Escherichia coli BW2952 putative ABC transporter ATP-binding protein YbbA YP_002925578.1 421716 D 595496 CDS YP_002925579.1 238899783 7955722 422399..424813 1 NC_012759.1 MG1655 equivalent: b0496; putative inner membrane protein 424813 ybbP 7955722 ybbP Escherichia coli BW2952 putative inner membrane protein YP_002925579.1 422399 D 595496 CDS YP_002925580.1 238899784 7955025 425244..429524 1 NC_012759.1 MG1655 equivalent: b0497; rhsD element protein 429524 rhsD 7955025 rhsD Escherichia coli BW2952 rhsD element protein YP_002925580.1 425244 D 595496 CDS YP_002925581.1 238899785 7955952 429564..429932 1 NC_012759.1 MG1655 equivalent: b0498; hypothetical protein 429932 ybbC 7955952 ybbC Escherichia coli BW2952 hypothetical protein YP_002925581.1 429564 D 595496 CDS YP_002925582.1 238899786 7955442 complement(432115..433209) 1 NC_012759.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 433209 ybbB 7955442 ybbB Escherichia coli BW2952 tRNA 2-selenouridine synthase YP_002925582.1 432115 R 595496 CDS YP_002925583.1 238899787 7956200 complement(433278..434204) 1 NC_012759.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 434204 allS 7956200 allS Escherichia coli BW2952 DNA-binding transcriptional activator AllS YP_002925583.1 433278 R 595496 CDS YP_002925584.1 238899788 7953394 434434..434916 1 NC_012759.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 434916 allA 7953394 allA Escherichia coli BW2952 ureidoglycolate hydrolase YP_002925584.1 434434 D 595496 CDS YP_002925585.1 238899789 7956260 434994..435809 1 NC_012759.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 435809 allR 7956260 allR Escherichia coli BW2952 DNA-binding transcriptional repressor AllR YP_002925585.1 434994 D 595496 CDS YP_002925586.1 238899790 7953462 435899..437680 1 NC_012759.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 437680 gcl 7953462 gcl Escherichia coli BW2952 glyoxylate carboligase YP_002925586.1 435899 D 595496 CDS YP_002925587.1 238899791 7953871 437693..438469 1 NC_012759.1 MG1655 equivalent: b0508; hydroxypyruvate isomerase 438469 hyi 7953871 hyi Escherichia coli BW2952 hydroxypyruvate isomerase YP_002925587.1 437693 D 595496 CDS YP_002925588.1 238899792 7953960 438569..439447 1 NC_012759.1 MG1655 equivalent: b0509; tartronate semialdehyde reductase, NADH-dependent 439447 glxR 7953960 glxR Escherichia coli BW2952 tartronate semialdehyde reductase, NADH-dependent YP_002925588.1 438569 D 595496 CDS YP_002925589.1 238899793 7956108 439616..441070 1 NC_012759.1 MG1655 equivalent: b0511; allantoin permease 441070 ybbW 7956108 ybbW Escherichia coli BW2952 allantoin permease YP_002925589.1 439616 D 595496 CDS YP_002925590.1 238899794 7954633 441130..442491 1 NC_012759.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 442491 allB 7954633 allB Escherichia coli BW2952 allantoinase YP_002925590.1 441130 D 595496 CDS YP_002925591.1 238899795 7952453 442548..443849 1 NC_012759.1 MG1655 equivalent: b0513; putative purine permease YbbY 443849 ybbY 7952453 ybbY Escherichia coli BW2952 putative purine permease YbbY YP_002925591.1 442548 D 595496 CDS YP_002925592.1 238899796 7955747 443871..445016 1 NC_012759.1 MG1655 equivalent: b0514; glycerate kinase 445016 glxK 7955747 glxK Escherichia coli BW2952 glycerate kinase YP_002925592.1 443871 D 595496 CDS YP_002925593.1 238899797 7953844 complement(445244..446029) 1 NC_012759.1 MG1655 equivalent: b0515; hypothetical protein 446029 ylbA 7953844 ylbA Escherichia coli BW2952 hypothetical protein YP_002925593.1 445244 R 595496 CDS YP_002925594.1 238899798 7952765 complement(446040..447275) 1 NC_012759.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 447275 allC 7952765 allC Escherichia coli BW2952 allantoate amidohydrolase YP_002925594.1 446040 R 595496 CDS YP_002925595.1 238899799 7952452 complement(447297..448346) 1 NC_012759.1 MG1655 equivalent: b0517; ureidoglycolate dehydrogenase 448346 allD 7952452 allD Escherichia coli BW2952 ureidoglycolate dehydrogenase YP_002925595.1 447297 R 595496 CDS YP_002925596.1 238899800 7956259 448663..450330 1 NC_012759.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 450330 fdrA 7956259 fdrA Escherichia coli BW2952 membrane protein FdrA YP_002925596.1 448663 D 595496 CDS YP_002925597.1 238899801 7954610 451610..452425 1 NC_012759.1 MG1655 equivalent: b0520; hypothetical protein 452425 ylbF 7954610 ylbF Escherichia coli BW2952 hypothetical protein YP_002925597.1 451610 D 595496 CDS YP_002925598.1 238899802 7952932 452422..453315 1 NC_012759.1 MG1655 equivalent: b0521; carbamate kinase 453315 ybcF 7952932 ybcF Escherichia coli BW2952 carbamate kinase YP_002925598.1 452422 D 595496 CDS YP_002925599.1 238899803 7954674 complement(453510..454577) 1 NC_012759.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 454577 purK 7954674 purK Escherichia coli BW2952 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002925599.1 453510 R 595496 CDS YP_002925600.1 238899804 7954331 complement(454574..455083) 1 NC_012759.1 MG1655 equivalent: b0523; N5-carboxyaminoimidazole ribonucleotide mutase 455083 purE 7954331 purE Escherichia coli BW2952 N5-carboxyaminoimidazole ribonucleotide mutase YP_002925600.1 454574 R 595496 CDS YP_002925601.1 238899805 7954330 complement(455201..455923) 1 NC_012759.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 455923 lpxH 7954330 lpxH Escherichia coli BW2952 UDP-2,3-diacylglucosamine hydrolase YP_002925601.1 455201 R 595496 CDS YP_002925602.1 238899806 7956225 complement(455926..456420) 1 NC_012759.1 MG1655 equivalent: b0525; peptidyl-prolyl cis-trans isomerase B 456420 ppiB 7956225 ppiB Escherichia coli BW2952 peptidyl-prolyl cis-trans isomerase B YP_002925602.1 455926 R 595496 CDS YP_002925603.1 238899807 7954483 456594..457979 1 NC_012759.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 457979 cysS 7954483 cysS Escherichia coli BW2952 cysteinyl-tRNA synthetase YP_002925603.1 456594 D 595496 CDS YP_002925604.1 238899808 7953186 complement(458015..458536) 1 NC_012759.1 MG1655 equivalent: b0527; hypothetical protein 458536 ybcI 7953186 ybcI Escherichia coli BW2952 hypothetical protein YP_002925604.1 458015 R 595496 CDS YP_002925605.1 238899809 7952665 complement(458644..458856) 1 NC_012759.1 MG1655 equivalent: b0528; hypothetical protein 458856 ybcJ 7952665 ybcJ Escherichia coli BW2952 hypothetical protein YP_002925605.1 458644 R 595496 CDS YP_002925606.1 238899810 7955572 complement(458858..459724) 1 NC_012759.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 459724 folD 7955572 folD Escherichia coli BW2952 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002925606.1 458858 R 595496 CDS YP_002925607.1 238899811 7952559 460195..460737 1 NC_012759.1 MG1655 equivalent: b0530; putative fimbrial-like adhesin protein 460737 sfmA 7952559 sfmA Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925607.1 460195 D 595496 CDS YP_002925608.1 238899812 7954892 460957..461649 1 NC_012759.1 MG1655 equivalent: b0531; pilin chaperone, periplasmic 461649 sfmC 7954892 sfmC Escherichia coli BW2952 pilin chaperone, periplasmic YP_002925608.1 460957 D 595496 CDS YP_002925609.1 238899813 7954560 461680..464283 1 NC_012759.1 MG1655 equivalent: b0532; putative outer membrane export usher protein 464283 sfmD 7954560 sfmD Escherichia coli BW2952 putative outer membrane export usher protein YP_002925609.1 461680 D 595496 CDS YP_002925610.1 238899814 7955196 464319..465302 1 NC_012759.1 MG1655 equivalent: b0533; putative fimbrial-like adhesin protein 465302 sfmH 7955196 sfmH Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925610.1 464319 D 595496 CDS YP_002925611.1 238899815 7954893 465313..465828 1 NC_012759.1 MG1655 equivalent: b0534; putative fimbrial protein 465828 sfmF 7954893 sfmF Escherichia coli BW2952 putative fimbrial protein YP_002925611.1 465313 D 595496 CDS YP_002925612.1 238899816 7954894 complement(465831..466463) 1 NC_012759.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 466463 fimZ 7954894 fimZ Escherichia coli BW2952 transcriptional regulator FimZ YP_002925612.1 465831 R 595496 CDS YP_002925613.1 238899817 7952120 complement(466798..467961) 1 NC_012759.1 MG1655 equivalent: b0537; DLP12 prophage; putative integrase 467961 intD 7952120 intD Escherichia coli BW2952 DLP12 prophage; putative integrase YP_002925613.1 466798 R 595496 CDS YP_002925614.1 238899818 7953284 468816..469124 1 NC_012759.1 MG1655 equivalent: b0540; IS3 element protein InsE 469124 insE 7953284 insE Escherichia coli BW2952 IS3 element protein InsE YP_002925614.1 468816 D 595496 CDS YP_002925615.1 238899819 7954030 469121..469987 1 NC_012759.1 MG1655 equivalent: b0541; IS3 element protein InsF 469987 insF 7954030 insF Escherichia coli BW2952 IS3 element protein InsF YP_002925615.1 469121 D 595496 CDS YP_002925616.1 238899820 7954034 470298..470630 1 NC_012759.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 470630 emrE 7954034 emrE Escherichia coli BW2952 multidrug efflux protein YP_002925616.1 470298 D 595496 CDS YP_002925617.1 238899821 7953280 470885..472411 1 NC_012759.1 MG1655 equivalent: b0544; DLP12 prophage; putative recombinase 472411 ybcK 7953280 ybcK Escherichia coli BW2952 DLP12 prophage; putative recombinase YP_002925617.1 470885 D 595496 CDS YP_002925618.1 238899822 7953296 472876..473427 1 NC_012759.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; putative kinase inhibitor 473427 ybcL 7953296 ybcL Escherichia coli BW2952 putative kinase inhibitor YP_002925618.1 472876 D 595496 CDS YP_002925619.1 238899823 7953285 473437..474234 1 NC_012759.1 MG1655 equivalent: b0546; DLP12 prophage; putative DNA-binding transcriptional regulator 474234 ybcM 7953285 ybcM Escherichia coli BW2952 DLP12 prophage; putative DNA-binding transcriptional regulator YP_002925619.1 473437 D 595496 CDS YP_002925620.1 238899824 7953283 474351..474452 1 NC_012759.1 MG1655 equivalent: b4588; hypothetical protein 474452 ylcH 7953283 ylcH Escherichia coli BW2952 hypothetical protein YP_002925620.1 474351 D 595496 CDS YP_002925621.1 238899825 7953983 474449..474904 1 NC_012759.1 DLP12 prophage; hypothetical protein 474904 ybcN 7953983 ybcN Escherichia coli BW2952 hypothetical protein YP_002925621.1 474449 D 595496 CDS YP_002925622.1 238899826 7953292 474904..475074 1 NC_012759.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 475074 ninE 7953292 ninE Escherichia coli BW2952 prophage protein NinE YP_002925622.1 474904 D 595496 CDS YP_002925623.1 238899827 7953276 475067..475357 1 NC_012759.1 MG1655 equivalent: b0549; DLP12 prophage protein 475357 ybcO 7953276 ybcO Escherichia coli BW2952 DLP12 prophage protein YP_002925623.1 475067 D 595496 CDS YP_002925624.1 238899828 7953293 475354..475716 1 NC_012759.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 475716 rusA 7953293 rusA Escherichia coli BW2952 endodeoxyribonuclease RUS YP_002925624.1 475354 D 595496 CDS YP_002925625.1 238899829 7953279 475713..475853 1 NC_012759.1 MG1655 equivalent: b4509; DLP12 prophage protein 475853 ylcG 7953279 ylcG Escherichia coli BW2952 DLP12 prophage protein YP_002925625.1 475713 D 595496 CDS YP_002925626.1 238899830 7953295 475939..476322 1 NC_012759.1 MG1655 equivalent: b0551; DLP12 prophage; putative antitermination protein 476322 quuD 7953295 quuD Escherichia coli BW2952 DLP12 prophage; putative antitermination protein YP_002925626.1 475939 D 595496 CDS YP_002925627.1 238899831 7953282 complement(476720..477736) 1 NC_012759.1 MG1655 equivalent: b0552; IS5 transposase and trans-activator 477736 insH 7953282 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002925627.1 476720 R 595496 CDS YP_002925628.1 238899832 7954037 479381..479596 1 NC_012759.1 MG1655 equivalent: b0554; DLP12 prophage; putative phage lysis protein 479596 essD 7954037 essD Escherichia coli BW2952 DLP12 prophage; putative phage lysis protein YP_002925628.1 479381 D 595496 CDS YP_002925629.1 238899833 7953290 479596..480093 1 NC_012759.1 MG1655 equivalent: b0555; DLP12 prophage; putative lysozyme 480093 arrD 7953290 arrD Escherichia coli BW2952 DLP12 prophage; putative lysozyme YP_002925629.1 479596 D 595496 CDS YP_002925630.1 238899834 7953288 480090..480551 1 NC_012759.1 MG1655 equivalent: b0556; DLP12 prophage; putative murein endopeptidase 480551 rzpD 7953288 rzpD Escherichia coli BW2952 DLP12 prophage; putative murein endopeptidase YP_002925630.1 480090 D 595496 CDS YP_002925631.1 238899835 7953289 480310..480492 1 NC_012759.1 MG1655 equivalent: b4510; DLP12 prophage; putative lipoprotein 480492 rzoD 7953289 rzoD Escherichia coli BW2952 DLP12 prophage; putative lipoprotein YP_002925631.1 480310 D 595496 CDS YP_002925632.1 238899836 7953287 complement(480583..480876) 1 NC_012759.1 MG1655 equivalent: b0557; DLP12 prophage; putative lipoprotein 480876 borD 7953287 borD Escherichia coli BW2952 DLP12 prophage; putative lipoprotein YP_002925632.1 480583 R 595496 CDS YP_002925633.1 238899837 7953286 complement(481167..481577) 1 NC_012759.1 MG1655 equivalent: b0558; DLP12 prophage protein 481577 ybcV 7953286 ybcV Escherichia coli BW2952 DLP12 prophage protein YP_002925633.1 481167 R 595496 CDS YP_002925634.1 238899838 7953291 481863..482069 1 NC_012759.1 MG1655 equivalent: b0559; DLP12 prophage protein 482069 ybcW 7953291 ybcW Escherichia coli BW2952 DLP12 prophage protein YP_002925634.1 481863 D 595496 CDS YP_002925635.1 238899839 7953294 complement(482234..482428) 1 NC_012759.1 MG1655 equivalent: b4589; hypothetical protein 482428 ylcI 7953294 ylcI Escherichia coli BW2952 hypothetical protein YP_002925635.1 482234 R 595496 CDS YP_002925636.1 238899840 7953962 482817..483362 1 NC_012759.1 MG1655 equivalent: b0560; DLP12 prophage; DNA packaging protein 483362 nohB 7953962 nohB Escherichia coli BW2952 DLP12 prophage; DNA packaging protein YP_002925636.1 482817 D 595496 CDS YP_002925637.1 238899841 7953277 485664..486413 1 NC_012759.1 MG1655 equivalent: b0564; DLP12 prophage; DNA-binding transcriptional activator 486413 appY 7953277 appY Escherichia coli BW2952 DLP12 prophage; DNA-binding transcriptional activator YP_002925637.1 485664 D 595496 CDS YP_002925638.1 238899842 7953278 complement(486663..487616) 1 NC_012759.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 487616 ompT 7953278 ompT Escherichia coli BW2952 outer membrane protease YP_002925638.1 486663 R 595496 CDS YP_002925639.1 238899843 7952121 complement(488130..488891) 1 NC_012759.1 MG1655 equivalent: b0566; DNA-binding transcriptional activator of porin biosynthesis 488891 envY 7952121 envY Escherichia coli BW2952 DNA-binding transcriptional activator of porin biosynthesis YP_002925639.1 488130 R 595496 CDS YP_002925640.1 238899844 7953392 complement(489074..489964) 1 NC_012759.1 MG1655 equivalent: b0567; hypothetical protein 489964 ybcH 7953392 ybcH Escherichia coli BW2952 hypothetical protein YP_002925640.1 489074 R 595496 CDS YP_002925641.1 238899845 7955339 complement(489965..492937) 1 NC_012759.1 MG1655 equivalent: b0568; bacteriophage N4 receptor, outer membrane subunit 492937 nfrA 7955339 nfrA Escherichia coli BW2952 bacteriophage N4 receptor, outer membrane subunit YP_002925641.1 489965 R 595496 CDS YP_002925642.1 238899846 7952544 complement(492924..495161) 1 NC_012759.1 MG1655 equivalent: b0569; bacteriophage N4 adsorption protein B 495161 nfrB 7952544 nfrB Escherichia coli BW2952 bacteriophage N4 adsorption protein B YP_002925642.1 492924 R 595496 CDS YP_002925643.1 238899847 7952543 complement(495311..496753) 1 NC_012759.1 MG1655 equivalent: b0570; sensor kinase CusS 496753 cusS 7952543 cusS Escherichia coli BW2952 sensor kinase CusS YP_002925643.1 495311 R 595496 CDS YP_002925644.1 238899848 7956017 complement(496743..497426) 1 NC_012759.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 497426 cusR 7956017 cusR Escherichia coli BW2952 DNA-binding transcriptional activator CusR YP_002925644.1 496743 R 595496 CDS YP_002925645.1 238899849 7953350 497583..498956 1 NC_012759.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 498956 cusC 7953350 cusC Escherichia coli BW2952 copper/silver efflux system outer membrane protein CusC YP_002925645.1 497583 D 595496 CDS YP_002925646.1 238899850 7953100 499114..499446 1 NC_012759.1 MG1655 equivalent: b0573; copper-binding protein 499446 cusF 7953100 cusF Escherichia coli BW2952 copper-binding protein YP_002925646.1 499114 D 595496 CDS YP_002925647.1 238899851 7954488 499462..500685 1 NC_012759.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 500685 cusB 7954488 cusB Escherichia coli BW2952 copper/silver efflux system membrane fusion protein CusB YP_002925647.1 499462 D 595496 CDS YP_002925648.1 238899852 7953099 500697..503840 1 NC_012759.1 MG1655 equivalent: b0575; copper/silver efflux system, membrane component 503840 cusA 7953099 cusA Escherichia coli BW2952 copper/silver efflux system, membrane component YP_002925648.1 500697 D 595496 CDS YP_002925649.1 238899853 7953098 503942..505318 1 NC_012759.1 MG1655 equivalent: b0576; phenylalanine transporter 505318 pheP 7953098 pheP Escherichia coli BW2952 phenylalanine transporter YP_002925649.1 503942 D 595496 CDS YP_002925650.1 238899854 7954508 complement(505399..506646) 1 NC_012759.1 MG1655 equivalent: b0577; putative mechanosensitive channel 506646 ybdG 7954508 ybdG Escherichia coli BW2952 putative mechanosensitive channel YP_002925650.1 505399 R 595496 CDS YP_002925651.1 238899855 7955135 complement(506754..507407) 1 NC_012759.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 507407 nfsB 7955135 nfsB Escherichia coli BW2952 dihydropteridine reductase YP_002925651.1 506754 R 595496 CDS YP_002925652.1 238899856 7953256 complement(507501..507869) 1 NC_012759.1 MG1655 equivalent: b0579; hypothetical protein 507869 ybdF 7953256 ybdF Escherichia coli BW2952 hypothetical protein YP_002925652.1 507501 R 595496 CDS YP_002925653.1 238899857 7952766 complement(507934..508182) 1 NC_012759.1 MG1655 equivalent: b0580; putative inner membrane protein 508182 ybdJ 7952766 ybdJ Escherichia coli BW2952 putative inner membrane protein YP_002925653.1 507934 R 595496 CDS YP_002925654.1 238899858 7954987 complement(508248..509366) 1 NC_012759.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 509366 ybdK 7954987 ybdK Escherichia coli BW2952 carboxylate-amine ligase YP_002925654.1 508248 R 595496 CDS YP_002925655.1 238899859 7953770 509819..509971 1 NC_012759.1 MG1655 equivalent: b4415; toxic polypeptide, small 509971 hokE 7953770 hokE Escherichia coli BW2952 toxic polypeptide, small YP_002925655.1 509819 D 595496 CDS YP_002925656.1 238899860 7956159 510048..511160 1 NC_012759.1 MG1655 equivalent: b0582; IS186/IS421 transposase 511160 insL 7956159 insL Escherichia coli BW2952 IS186/IS421 transposase YP_002925656.1 510048 D 595496 CDS YP_002925657.1 238899861 7954026 complement(511442..512071) 1 NC_012759.1 MG1655 equivalent: b0583; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 512071 entD 7954026 entD Escherichia coli BW2952 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_002925657.1 511442 R 595496 CDS YP_002925658.1 238899862 7954546 complement(512237..514477) 1 NC_012759.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 514477 fepA 7954546 fepA Escherichia coli BW2952 outer membrane receptor FepA YP_002925658.1 512237 R 595496 CDS YP_002925659.1 238899863 7954013 514798..515922 1 NC_012759.1 MG1655 equivalent: b0585; enterobactin/ferric enterobactin esterase 515922 fes 7954013 fes Escherichia coli BW2952 enterobactin/ferric enterobactin esterase YP_002925659.1 514798 D 595496 CDS YP_002925660.1 238899864 7953528 515925..516143 1 NC_012759.1 MG1655 equivalent: b4511; hypothetical protein 516143 ybdZ 7953528 ybdZ Escherichia coli BW2952 hypothetical protein YP_002925660.1 515925 D 595496 CDS YP_002925661.1 238899865 7953070 516140..520021 1 NC_012759.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 520021 entF 7953070 entF Escherichia coli BW2952 enterobactin synthase subunit F YP_002925661.1 516140 D 595496 CDS YP_002925662.1 238899866 7953527 520237..521370 1 NC_012759.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 521370 fepE 7953527 fepE Escherichia coli BW2952 ferric enterobactin transport protein FepE YP_002925662.1 520237 D 595496 CDS YP_002925663.1 238899867 7955921 complement(521367..522182) 1 NC_012759.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 522182 fepC 7955921 fepC Escherichia coli BW2952 iron-enterobactin transporter ATP-binding protein YP_002925663.1 521367 R 595496 CDS YP_002925664.1 238899868 7954014 complement(522179..523171) 1 NC_012759.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 523171 fepG 7954014 fepG Escherichia coli BW2952 iron-enterobactin transporter permease YP_002925664.1 522179 R 595496 CDS YP_002925665.1 238899869 7954015 complement(523168..524172) 1 NC_012759.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 524172 fepD 7954015 fepD Escherichia coli BW2952 iron-enterobactin transporter membrane protein YP_002925665.1 523168 R 595496 CDS YP_002925666.1 238899870 7954016 524283..525533 1 NC_012759.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 525533 entS 7954016 entS Escherichia coli BW2952 enterobactin exporter EntS YP_002925666.1 524283 D 595496 CDS YP_002925667.1 238899871 7955680 complement(525537..526493) 1 NC_012759.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 526493 fepB 7955680 fepB Escherichia coli BW2952 iron-enterobactin transporter periplasmic binding protein YP_002925667.1 525537 R 595496 CDS YP_002925668.1 238899872 7954017 526868..528043 1 NC_012759.1 MG1655 equivalent: b0593; isochorismate synthase 1 528043 entC 7954017 entC Escherichia coli BW2952 isochorismate synthase 1 YP_002925668.1 526868 D 595496 CDS YP_002925669.1 238899873 7954049 528053..529663 1 NC_012759.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 529663 entE 7954049 entE Escherichia coli BW2952 enterobactin synthase subunit E YP_002925669.1 528053 D 595496 CDS YP_002925670.1 238899874 7952235 529677..530534 1 NC_012759.1 MG1655 equivalent: b0595; isochorismatase 530534 entB 7952235 entB Escherichia coli BW2952 isochorismatase YP_002925670.1 529677 D 595496 CDS YP_002925671.1 238899875 7954048 530534..531280 1 NC_012759.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 531280 entA 7954048 entA Escherichia coli BW2952 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_002925671.1 530534 D 595496 CDS YP_002925672.1 238899876 7952233 531283..531696 1 NC_012759.1 MG1655 equivalent: b0597; hypothetical protein 531696 ybdB 7952233 ybdB Escherichia coli BW2952 hypothetical protein YP_002925672.1 531283 D 595496 CDS YP_002925673.1 238899877 7952933 531877..533982 1 NC_012759.1 MG1655 equivalent: b0598; carbon starvation protein 533982 cstA 7952933 cstA Escherichia coli BW2952 carbon starvation protein YP_002925673.1 531877 D 595496 CDS YP_002925674.1 238899878 7952596 534165..534362 1 NC_012759.1 MG1655 equivalent: b4512; hypothetical protein 534362 ybdD 7952596 ybdD Escherichia coli BW2952 hypothetical protein YP_002925674.1 534165 D 595496 CDS YP_002925675.1 238899879 7953071 complement(534372..535460) 1 NC_012759.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 535460 ybdH 7953071 ybdH Escherichia coli BW2952 hypothetical protein YP_002925675.1 534372 R 595496 CDS YP_002925676.1 238899880 7955221 535569..536729 1 NC_012759.1 catalyzes the transfer of an amino moiety; putative aminotransferase 536729 ybdL 7955221 ybdL Escherichia coli BW2952 putative aminotransferase YP_002925676.1 535569 D 595496 CDS YP_002925677.1 238899881 7954244 complement(536730..537359) 1 NC_012759.1 MG1655 equivalent: b0601; hypothetical protein 537359 ybdM 7954244 ybdM Escherichia coli BW2952 hypothetical protein YP_002925677.1 536730 R 595496 CDS YP_002925678.1 238899882 7952767 complement(537332..538552) 1 NC_012759.1 MG1655 equivalent: b0602; hypothetical protein 538552 ybdN 7952767 ybdN Escherichia coli BW2952 hypothetical protein YP_002925678.1 537332 R 595496 CDS YP_002925679.1 238899883 7952768 complement(538699..539601) 1 NC_012759.1 MG1655 equivalent: b0603; putative DNA-binding transcriptional regulator 539601 ybdO 7952768 ybdO Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925679.1 538699 R 595496 CDS YP_002925680.1 238899884 7954747 complement(539810..540556) 1 NC_012759.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 540556 dsbG 7954747 dsbG Escherichia coli BW2952 disulfide isomerase/thiol-disulfide oxidase YP_002925680.1 539810 R 595496 CDS YP_002925681.1 238899885 7954489 540928..541491 1 NC_012759.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 541491 ahpC 7954489 ahpC Escherichia coli BW2952 alkyl hydroperoxide reductase subunit C YP_002925681.1 540928 D 595496 CDS YP_002925682.1 238899886 7952450 541736..543301 1 NC_012759.1 MG1655 equivalent: b0606; alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding 543301 ahpF 7952450 ahpF Escherichia coli BW2952 alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding YP_002925682.1 541736 D 595496 CDS YP_002925683.1 238899887 7952451 complement(543422..543850) 1 NC_012759.1 MG1655 equivalent: b0607; universal stress protein UP12 543850 uspG 7952451 uspG Escherichia coli BW2952 universal stress protein UP12 YP_002925683.1 543422 R 595496 CDS YP_002925684.1 238899888 7956255 544071..545309 1 NC_012759.1 MG1655 equivalent: b0608; putative oxidoreductase, Zn-dependent and NAD(P)-binding 545309 ybdR 7956255 ybdR Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002925684.1 544071 D 595496 CDS YP_002925685.1 238899889 7955262 complement(545540..545950) 1 NC_012759.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 545950 rnk 7955262 rnk Escherichia coli BW2952 nucleoside diphosphate kinase regulator YP_002925685.1 545540 R 595496 CDS YP_002925686.1 238899890 7955922 complement(546180..546986) 1 NC_012759.1 MG1655 equivalent: b0611; ribonuclease I 546986 rna 7955922 rna Escherichia coli BW2952 ribonuclease I YP_002925686.1 546180 R 595496 CDS YP_002925687.1 238899891 7955961 complement(547100..548563) 1 NC_012759.1 MG1655 equivalent: b0612; citrate:succinate antiporter 548563 citT 7955961 citT Escherichia coli BW2952 citrate:succinate antiporter YP_002925687.1 547100 R 595496 CDS YP_002925688.1 238899892 7952644 complement(548614..549492) 1 NC_012759.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 549492 citG 7952644 citG Escherichia coli BW2952 triphosphoribosyl-dephospho-CoA synthase YP_002925688.1 548614 R 595496 CDS YP_002925689.1 238899893 7956194 complement(549467..550018) 1 NC_012759.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 550018 citX 7956194 citX Escherichia coli BW2952 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_002925689.1 549467 R 595496 CDS YP_002925690.1 238899894 7952489 complement(550022..551554) 1 NC_012759.1 MG1655 equivalent: b0615; citrate lyase, citrate-ACP transferase (alpha) subunit 551554 citF 7952489 citF Escherichia coli BW2952 citrate lyase, citrate-ACP transferase (alpha) subunit YP_002925690.1 550022 R 595496 CDS YP_002925691.1 238899895 7952641 complement(551565..552473) 1 NC_012759.1 MG1655 equivalent: b0616; citrate lyase, citryl-ACP lyase (beta) subunit 552473 citE 7952641 citE Escherichia coli BW2952 citrate lyase, citryl-ACP lyase (beta) subunit YP_002925691.1 551565 R 595496 CDS YP_002925692.1 238899896 7952642 complement(552470..552766) 1 NC_012759.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 552766 citD 7952642 citD Escherichia coli BW2952 citrate lyase subunit gamma YP_002925692.1 552470 R 595496 CDS YP_002925693.1 238899897 7952640 complement(552781..553839) 1 NC_012759.1 MG1655 equivalent: b0618; citrate lyase synthetase 553839 citC 7952640 citC Escherichia coli BW2952 citrate lyase synthetase YP_002925693.1 552781 R 595496 CDS YP_002925694.1 238899898 7952639 554218..555876 1 NC_012759.1 MG1655 equivalent: b0619; sensory histidine kinase in two-component regulatory system with citB 555876 dpiB 7952639 dpiB Escherichia coli BW2952 sensory histidine kinase in two-component regulatory system with citB YP_002925694.1 554218 D 595496 CDS YP_002925695.1 238899899 7956014 555845..556525 1 NC_012759.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 556525 dpiA 7956014 dpiA Escherichia coli BW2952 two-component response regulator DpiA YP_002925695.1 555845 D 595496 CDS YP_002925696.1 238899900 7953347 complement(556566..557951) 1 NC_012759.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 557951 dcuC 7953347 dcuC Escherichia coli BW2952 C4-dicarboxylate transporter DcuC YP_002925696.1 556566 R 595496 CDS YP_002925697.1 238899901 7952476 558540..559100 1 NC_012759.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 559100 pagP 7952476 pagP Escherichia coli BW2952 palmitoyl transferase YP_002925697.1 558540 D 595496 CDS YP_002925698.1 238899902 7954462 559275..559484 1 NC_012759.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 559484 cspE 7954462 cspE Escherichia coli BW2952 cold shock protein CspE YP_002925698.1 559275 D 595496 CDS YP_002925699.1 238899903 7953463 complement(559538..559921) 1 NC_012759.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 559921 crcB 7953463 crcB Escherichia coli BW2952 camphor resistance protein CrcB YP_002925699.1 559538 R 595496 CDS YP_002925700.1 238899904 7955075 560930..561133 1 NC_012759.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 561133 tatE 7955075 tatE Escherichia coli BW2952 twin arginine translocase protein E YP_002925700.1 560930 D 595496 CDS YP_002925701.1 238899905 7956109 complement(561234..562199) 1 NC_012759.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 562199 lipA 7956109 lipA Escherichia coli BW2952 lipoyl synthase YP_002925701.1 561234 R 595496 CDS YP_002925702.1 238899906 7954147 complement(562408..563361) 1 NC_012759.1 MG1655 equivalent: b0629; putative DNA-binding transcriptional regulator 563361 ybeF 7954147 ybeF Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925702.1 562408 R 595496 CDS YP_002925703.1 238899907 7954748 complement(563620..564261) 1 NC_012759.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 564261 lipB 7954748 lipB Escherichia coli BW2952 lipoate-protein ligase B YP_002925703.1 563620 R 595496 CDS YP_002925704.1 238899908 7954159 complement(564362..564625) 1 NC_012759.1 MG1655 equivalent: b0631; hypothetical protein 564625 ybeD 7954159 ybeD Escherichia coli BW2952 hypothetical protein YP_002925704.1 564362 R 595496 CDS YP_002925705.1 238899909 7952769 complement(564735..565946) 1 NC_012759.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 565946 dacA 7952769 dacA Escherichia coli BW2952 D-alanyl-D-alanine carboxypeptidase YP_002925705.1 564735 R 595496 CDS YP_002925706.1 238899910 7953218 complement(566085..567173) 1 NC_012759.1 MG1655 equivalent: b0633; rare lipoprotein A 567173 rlpA 7953218 rlpA Escherichia coli BW2952 rare lipoprotein A YP_002925706.1 566085 R 595496 CDS YP_002925707.1 238899911 7954267 complement(567184..568296) 1 NC_012759.1 MG1655 equivalent: b0634; cell wall shape-determining protein 568296 mrdB 7954267 mrdB Escherichia coli BW2952 cell wall shape-determining protein YP_002925707.1 567184 R 595496 CDS YP_002925708.1 238899912 7952619 complement(568299..570200) 1 NC_012759.1 MG1655 equivalent: b0635; penicillin-binding protein 2 570200 mrdA 7952619 mrdA Escherichia coli BW2952 penicillin-binding protein 2 YP_002925708.1 568299 R 595496 CDS YP_002925709.1 238899913 7956177 complement(570231..570698) 1 NC_012759.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 570698 ybeA 7956177 ybeA Escherichia coli BW2952 rRNA large subunit methyltransferase YP_002925709.1 570231 R 595496 CDS YP_002925710.1 238899914 7952770 complement(570702..571019) 1 NC_012759.1 MG1655 equivalent: b0637; hypothetical protein 571019 ybeB 7952770 ybeB Escherichia coli BW2952 hypothetical protein YP_002925710.1 570702 R 595496 CDS YP_002925711.1 238899915 7955340 complement(571279..571890) 1 NC_012759.1 MG1655 equivalent: b0638; putative alpha-ribazole-5'-P phosphatase 571890 cobC 7955340 cobC Escherichia coli BW2952 putative alpha-ribazole-5'-P phosphatase YP_002925711.1 571279 R 595496 CDS YP_002925712.1 238899916 7954635 complement(571914..572555) 1 NC_012759.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 572555 nadD 7954635 nadD Escherichia coli BW2952 nicotinic acid mononucleotide adenylyltransferase YP_002925712.1 571914 R 595496 CDS YP_002925713.1 238899917 7954385 complement(572557..573588) 1 NC_012759.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 573588 holA 7954385 holA Escherichia coli BW2952 DNA polymerase III subunit delta YP_002925713.1 572557 R 595496 CDS YP_002925714.1 238899918 7953323 complement(573588..574169) 1 NC_012759.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 574169 rlpB 7953323 rlpB Escherichia coli BW2952 LPS-assembly lipoprotein RlpB YP_002925714.1 573588 R 595496 CDS YP_002925715.1 238899919 7954268 complement(574184..576766) 1 NC_012759.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 576766 leuS 7954268 leuS Escherichia coli BW2952 leucyl-tRNA synthetase YP_002925715.1 574184 R 595496 CDS YP_002925716.1 238899920 7954132 577001..577483 1 NC_012759.1 MG1655 equivalent: b0643; hypothetical protein 577483 ybeL 7954132 ybeL Escherichia coli BW2952 hypothetical protein YP_002925716.1 577001 D 595496 CDS YP_002925717.1 238899921 7952934 complement(577553..578530) 1 NC_012759.1 MG1655 equivalent: b0644; hypothetical protein 578530 ybeQ 7952934 ybeQ Escherichia coli BW2952 hypothetical protein YP_002925717.1 577553 R 595496 CDS YP_002925718.1 238899922 7952771 578694..579401 1 NC_012759.1 MG1655 equivalent: b0645; hypothetical protein 579401 ybeR 7952771 ybeR Escherichia coli BW2952 hypothetical protein YP_002925718.1 578694 D 595496 CDS YP_002925719.1 238899923 7955443 579398..580825 1 NC_012759.1 MG1655 equivalent: b0646; putative chaperone 580825 djlB 7955443 djlB Escherichia coli BW2952 putative chaperone YP_002925719.1 579398 D 595496 CDS YP_002925720.1 238899924 7954687 complement(580835..581389) 1 NC_012759.1 MG1655 equivalent: b0647; hypothetical protein 581389 ybeT 7954687 ybeT Escherichia coli BW2952 hypothetical protein YP_002925720.1 580835 R 595496 CDS YP_002925721.1 238899925 7952748 581491..582198 1 NC_012759.1 MG1655 equivalent: b0648; putative tRNA ligase 582198 ybeU 7952748 ybeU Escherichia coli BW2952 putative tRNA ligase YP_002925721.1 581491 D 595496 CDS YP_002925722.1 238899926 7955744 582195..583646 1 NC_012759.1 MG1655 equivalent: b0649; Hsc56 co-chaperone of HscC 583646 djlC 7955744 djlC Escherichia coli BW2952 Hsc56 co-chaperone of HscC YP_002925722.1 582195 D 595496 CDS YP_002925723.1 238899927 7953923 complement(583706..585376) 1 NC_012759.1 MG1655 equivalent: b0650; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription 585376 hscC 7953923 hscC Escherichia coli BW2952 Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription YP_002925723.1 583706 R 595496 CDS YP_002925724.1 238899928 7953925 complement(585460..586395) 1 NC_012759.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 586395 rihA 7953925 rihA Escherichia coli BW2952 ribonucleoside hydrolase 1 YP_002925724.1 585460 R 595496 CDS YP_002925725.1 238899929 7955966 complement(586513..587238) 1 NC_012759.1 MG1655 equivalent: b0652; glutamate and aspartate transporter subunit 587238 gltL 7955966 gltL Escherichia coli BW2952 glutamate and aspartate transporter subunit YP_002925725.1 586513 R 595496 CDS YP_002925726.1 238899930 7953814 complement(587238..587912) 1 NC_012759.1 MG1655 equivalent: b0653; glutamate and aspartate transporter subunit 587912 gltK 7953814 gltK Escherichia coli BW2952 glutamate and aspartate transporter subunit YP_002925726.1 587238 R 595496 CDS YP_002925727.1 238899931 7953815 complement(587912..588652) 1 NC_012759.1 MG1655 equivalent: b0654; glutamate and aspartate transporter subunit 588652 gltJ 7953815 gltJ Escherichia coli BW2952 glutamate and aspartate transporter subunit YP_002925727.1 587912 R 595496 CDS YP_002925728.1 238899932 7953816 complement(588822..589730) 1 NC_012759.1 MG1655 equivalent: b0655; glutamate and aspartate transporter subunit 589730 gltI 7953816 gltI Escherichia coli BW2952 glutamate and aspartate transporter subunit YP_002925728.1 588822 R 595496 CDS YP_002925729.1 238899933 7953817 complement(589980..590996) 1 NC_012759.1 MG1655 equivalent: b0656; IS5 transposase and trans-activator 590996 insH 7953817 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002925729.1 589980 R 595496 CDS YP_002925730.1 238899934 7954038 complement(591326..592864) 1 NC_012759.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 592864 lnt 7954038 lnt Escherichia coli BW2952 apolipoprotein N-acyltransferase YP_002925730.1 591326 R 595496 CDS YP_002925731.1 238899935 7952490 complement(592889..593767) 1 NC_012759.1 MG1655 equivalent: b0658; predicteed ion transport 593767 ybeX 7952490 ybeX Escherichia coli BW2952 predicteed ion transport YP_002925731.1 592889 R 595496 CDS YP_002925732.1 238899936 7955758 complement(593857..594324) 1 NC_012759.1 MG1655 equivalent: b0659; putative metalloprotease 594324 ybeY 7955758 ybeY Escherichia coli BW2952 putative metalloprotease YP_002925732.1 593857 R 595496 CDS YP_002925733.1 238899937 7952772 complement(594321..595361) 1 NC_012759.1 MG1655 equivalent: b0660; hypothetical protein 595361 ybeZ 7952772 ybeZ Escherichia coli BW2952 hypothetical protein YP_002925733.1 594321 R 595496 CDS YP_002925734.1 238899938 7955542 complement(595514..596938) 1 NC_012759.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 596938 miaB 7955542 miaB Escherichia coli BW2952 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002925734.1 595514 R 595496 CDS YP_002925735.1 238899939 7954055 597084..598259 1 NC_012759.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 598259 ubiF 7954055 ubiF Escherichia coli BW2952 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002925735.1 597084 D 595496 CDS YP_002925736.1 238899940 7952047 complement(599496..601160) 1 NC_012759.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 601160 asnB 7952047 asnB Escherichia coli BW2952 asparagine synthetase B YP_002925736.1 599496 R 595496 CDS YP_002925737.1 238899941 7952508 complement(601557..602309) 1 NC_012759.1 MG1655 equivalent: b0675; UMP phosphatase 602309 nagD 7952508 nagD Escherichia coli BW2952 UMP phosphatase YP_002925737.1 601557 R 595496 CDS YP_002925738.1 238899942 7956246 complement(602357..603577) 1 NC_012759.1 MG1655 equivalent: b0676; DNA-binding transcriptional dual regulator 603577 nagC 7956246 nagC Escherichia coli BW2952 DNA-binding transcriptional dual regulator YP_002925738.1 602357 R 595496 CDS YP_002925739.1 238899943 7953436 complement(603586..604734) 1 NC_012759.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 604734 nagA 7953436 nagA Escherichia coli BW2952 N-acetylglucosamine-6-phosphate deacetylase YP_002925739.1 603586 R 595496 CDS YP_002925740.1 238899944 7954341 complement(604794..605594) 1 NC_012759.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 605594 nagB 7954341 nagB Escherichia coli BW2952 glucosamine-6-phosphate deaminase YP_002925740.1 604794 R 595496 CDS YP_002925741.1 238899945 7953802 605927..607873 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 607873 nagE 7953802 nagE Escherichia coli BW2952 PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_002925741.1 605927 D 595496 CDS YP_002925742.1 238899946 7953702 608076..609740 1 NC_012759.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 609740 glnS 7953702 glnS Escherichia coli BW2952 glutaminyl-tRNA synthetase YP_002925742.1 608076 D 595496 CDS YP_002925743.1 238899947 7953834 610317..611723 1 NC_012759.1 MG1655 equivalent: b0681; putative outer membrane porin 611723 ybfM 7953834 ybfM Escherichia coli BW2952 putative outer membrane porin YP_002925743.1 610317 D 595496 CDS YP_002925744.1 238899948 7955206 611773..612099 1 NC_012759.1 MG1655 equivalent: b0682; putative lipoprotein 612099 ybfN 7955206 ybfN Escherichia coli BW2952 putative lipoprotein YP_002925744.1 611773 D 595496 CDS YP_002925745.1 238899949 7955112 complement(612183..612629) 1 NC_012759.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 612629 fur 7955112 fur Escherichia coli BW2952 ferric uptake regulator YP_002925745.1 612183 R 595496 CDS YP_002925746.1 238899950 7953427 complement(612622..612708) 1 NC_012759.1 MG1655 equivalent: b4637; ryhB-regulated fur leader peptide 612708 uof 7953427 uof Escherichia coli BW2952 ryhB-regulated fur leader peptide YP_002925746.1 612622 R 595496 CDS YP_002925747.1 238899951 7955996 complement(612918..613448) 1 NC_012759.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 613448 fldA 7955996 fldA Escherichia coli BW2952 flavodoxin FldA YP_002925747.1 612918 R 595496 CDS YP_002925748.1 238899952 7953609 complement(613588..613881) 1 NC_012759.1 MG1655 equivalent: b0685; LexA regulated protein 613881 ybfE 7953609 ybfE Escherichia coli BW2952 LexA regulated protein YP_002925748.1 613588 R 595496 CDS YP_002925749.1 238899953 7954133 complement(614021..614785) 1 NC_012759.1 MG1655 equivalent: b0686; hypothetical protein 614785 ybfF 7954133 ybfF Escherichia coli BW2952 hypothetical protein YP_002925749.1 614021 R 595496 CDS YP_002925750.1 238899954 7952773 614970..615515 1 NC_012759.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 615515 seqA 7952773 seqA Escherichia coli BW2952 replication initiation regulator SeqA YP_002925750.1 614970 D 595496 CDS YP_002925751.1 238899955 7955935 615541..617181 1 NC_012759.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 617181 pgm 7955935 pgm Escherichia coli BW2952 phosphoglucomutase YP_002925751.1 615541 D 595496 CDS YP_002925752.1 238899956 7954531 617395..617889 1 NC_012759.1 MG1655 equivalent: b0689; hypothetical protein 617889 ybfP 7954531 ybfP Escherichia coli BW2952 hypothetical protein YP_002925752.1 617395 D 595496 CDS YP_002925753.1 238899957 7955444 complement(618929..620248) 1 NC_012759.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 620248 potE 7955444 potE Escherichia coli BW2952 putrescine transporter YP_002925753.1 618929 R 595496 CDS YP_002925754.1 238899958 7955832 complement(620245..622443) 1 NC_012759.1 MG1655 equivalent: b0693; ornithine decarboxylase 622443 speF 7955832 speF Escherichia coli BW2952 ornithine decarboxylase YP_002925754.1 620245 R 595496 CDS YP_002925755.1 238899959 7954429 622566..622823 1 NC_012759.1 MG1655 equivalent: b4590; hypothetical protein 622823 ybfK 7954429 ybfK Escherichia coli BW2952 hypothetical protein YP_002925755.1 622566 D 595496 CDS YP_002925756.1 238899960 7953975 complement(623039..623716) 1 NC_012759.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 623716 kdpE 7953975 kdpE Escherichia coli BW2952 DNA-binding transcriptional activator KdpE YP_002925756.1 623039 R 595496 CDS YP_002925757.1 238899961 7953354 complement(623713..626397) 1 NC_012759.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 626397 kdpD 7953354 kdpD Escherichia coli BW2952 sensor protein KdpD YP_002925757.1 623713 R 595496 CDS YP_002925758.1 238899962 7953741 complement(626390..626962) 1 NC_012759.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 626962 kdpC 7953741 kdpC Escherichia coli BW2952 potassium-transporting ATPase subunit C YP_002925758.1 626390 R 595496 CDS YP_002925759.1 238899963 7954575 complement(626971..629019) 1 NC_012759.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 629019 kdpB 7954575 kdpB Escherichia coli BW2952 potassium-transporting ATPase subunit B YP_002925759.1 626971 R 595496 CDS YP_002925760.1 238899964 7954574 complement(629042..630715) 1 NC_012759.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 630715 kdpA 7954574 kdpA Escherichia coli BW2952 potassium-transporting ATPase subunit A YP_002925760.1 629042 R 595496 CDS YP_002925761.1 238899965 7954573 complement(630715..630804) 1 NC_012759.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit F 630804 kdpF 7954573 kdpF Escherichia coli BW2952 potassium-transporting ATPase subunit F YP_002925761.1 630715 R 595496 CDS YP_002925762.1 238899966 7954572 631117..631323 1 NC_012759.1 MG1655 equivalent: b0699; hypothetical protein 631323 ybfA 7954572 ybfA Escherichia coli BW2952 hypothetical protein YP_002925762.1 631117 D 595496 CDS YP_002925763.1 238899967 7955445 631566..635759 1 NC_012759.1 MG1655 equivalent: b0700; rhsC element core protein RshC 635759 rhsC 7955445 rhsC Escherichia coli BW2952 rhsC element core protein RshC YP_002925763.1 631566 D 595496 CDS YP_002925764.1 238899968 7955951 635759..636085 1 NC_012759.1 MG1655 equivalent: b0702; putative inner membrane protein 636085 ybfB 7955951 ybfB Escherichia coli BW2952 putative inner membrane protein YP_002925764.1 635759 D 595496 CDS YP_002925765.1 238899969 7955026 637633..638202 1 NC_012759.1 MG1655 equivalent: b0704; hypothetical protein 638202 ybfC 7955026 ybfC Escherichia coli BW2952 hypothetical protein YP_002925765.1 637633 D 595496 CDS YP_002925766.1 238899970 7955446 638428..638682 1 NC_012759.1 MG1655 equivalent: b4514; putative transposase 638682 ybfQ 7955446 ybfQ Escherichia coli BW2952 putative transposase YP_002925766.1 638428 D 595496 CDS YP_002925767.1 238899971 7955743 640075..640836 1 NC_012759.1 MG1655 equivalent: b0706; hypothetical protein 640836 ybfD 7955743 ybfD Escherichia coli BW2952 hypothetical protein YP_002925767.1 640075 D 595496 CDS YP_002925768.1 238899972 7952935 640984..641493 1 NC_012759.1 MG1655 equivalent: b0707; hypothetical protein 641493 ybgA 7952935 ybgA Escherichia coli BW2952 hypothetical protein YP_002925768.1 640984 D 595496 CDS YP_002925769.1 238899973 7952936 641490..642908 1 NC_012759.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 642908 phr 7952936 phr Escherichia coli BW2952 deoxyribodipyrimidine photolyase YP_002925769.1 641490 D 595496 CDS YP_002925770.1 238899974 7953235 complement(643058..644539) 1 NC_012759.1 MG1655 equivalent: b0709; putative transporter 644539 ybgH 7953235 ybgH Escherichia coli BW2952 putative transporter YP_002925770.1 643058 R 595496 CDS YP_002925771.1 238899975 7955650 644810..645553 1 NC_012759.1 MG1655 equivalent: b0710; putative hydrolase-oxidase 645553 ybgI 7955650 ybgI Escherichia coli BW2952 putative hydrolase-oxidase YP_002925771.1 644810 D 595496 CDS YP_002925772.1 238899976 7952746 645576..646232 1 NC_012759.1 MG1655 equivalent: b0711; putative enzyme subunit 646232 ybgJ 7952746 ybgJ Escherichia coli BW2952 putative enzyme subunit YP_002925772.1 645576 D 595496 CDS YP_002925773.1 238899977 7954858 646226..647158 1 NC_012759.1 MG1655 equivalent: b0712; putative enzyme subunit 647158 ybgK 7954858 ybgK Escherichia coli BW2952 putative enzyme subunit YP_002925773.1 646226 D 595496 CDS YP_002925774.1 238899978 7954859 647148..647882 1 NC_012759.1 MG1655 equivalent: b0713; LamB/YcsF family protein 647882 ybgL 7954859 ybgL Escherichia coli BW2952 LamB/YcsF family protein YP_002925774.1 647148 D 595496 CDS YP_002925775.1 238899979 7955098 647918..648709 1 NC_012759.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 648709 nei 7955098 nei Escherichia coli BW2952 endonuclease VIII YP_002925775.1 647918 D 595496 CDS YP_002925776.1 238899980 7953521 complement(648706..649752) 1 NC_012759.1 MG1655 equivalent: b0715; putative regulator 649752 abrB 7953521 abrB Escherichia coli BW2952 putative regulator YP_002925776.1 648706 R 595496 CDS YP_002925777.1 238899981 7955558 complement(649904..650965) 1 NC_012759.1 MG1655 equivalent: b0716; putative fimbrial-like adhesin protein 650965 ybgO 7955558 ybgO Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925777.1 649904 R 595496 CDS YP_002925778.1 238899982 7954881 complement(650962..651690) 1 NC_012759.1 MG1655 equivalent: b0717; putative assembly protein 651690 ybgP 7954881 ybgP Escherichia coli BW2952 putative assembly protein YP_002925778.1 650962 R 595496 CDS YP_002925779.1 238899983 7954659 complement(651705..654152) 1 NC_012759.1 MG1655 equivalent: b0718; putative outer membrane protein 654152 ybgQ 7954659 ybgQ Escherichia coli BW2952 putative outer membrane protein YP_002925779.1 651705 R 595496 CDS YP_002925780.1 238899984 7955210 complement(654212..654778) 1 NC_012759.1 MG1655 equivalent: b0719; putative fimbrial-like adhesin protein 654778 ybgD 7955210 ybgD Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925780.1 654212 R 595496 CDS YP_002925781.1 238899985 7954882 complement(655168..656451) 1 NC_012759.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 656451 gltA 7954882 gltA Escherichia coli BW2952 type II citrate synthase YP_002925781.1 655168 R 595496 CDS YP_002925782.1 238899986 7952643 657160..657549 1 NC_012759.1 MG1655 equivalent: b0721; succinate dehydrogenase cytochrome b556 large membrane subunit 657549 sdhC 7952643 sdhC Escherichia coli BW2952 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002925782.1 657160 D 595496 CDS YP_002925783.1 238899987 7956078 657543..657890 1 NC_012759.1 MG1655 equivalent: b0722; succinate dehydrogenase cytochrome b556 small membrane subunit 657890 sdhD 7956078 sdhD Escherichia coli BW2952 succinate dehydrogenase cytochrome b556 small membrane subunit YP_002925783.1 657543 D 595496 CDS YP_002925784.1 238899988 7956079 657890..659656 1 NC_012759.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 659656 sdhA 7956079 sdhA Escherichia coli BW2952 succinate dehydrogenase flavoprotein subunit YP_002925784.1 657890 D 595496 CDS YP_002925785.1 238899989 7956077 659672..660388 1 NC_012759.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 660388 sdhB 7956077 sdhB Escherichia coli BW2952 succinate dehydrogenase iron-sulfur subunit YP_002925785.1 659672 D 595496 CDS YP_002925786.1 238899990 7956076 660689..663490 1 NC_012759.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 663490 sucA 7956076 sucA Escherichia coli BW2952 2-oxoglutarate dehydrogenase E1 component YP_002925786.1 660689 D 595496 CDS YP_002925787.1 238899991 7952269 663505..664722 1 NC_012759.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 664722 sucB 7952269 sucB Escherichia coli BW2952 dihydrolipoamide succinyltransferase YP_002925787.1 663505 D 595496 CDS YP_002925788.1 238899992 7953253 664997..666163 1 NC_012759.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 666163 sucC 7953253 sucC Escherichia coli BW2952 succinyl-CoA synthetase subunit beta YP_002925788.1 664997 D 595496 CDS YP_002925789.1 238899993 7956082 666163..667032 1 NC_012759.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 667032 sucD 7956082 sucD Escherichia coli BW2952 succinyl-CoA synthetase subunit alpha YP_002925789.1 666163 D 595496 CDS YP_002925790.1 238899994 7956083 complement(667136..667858) 1 NC_012759.1 regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 667858 mngR 7956083 mngR Escherichia coli BW2952 DNA-binding transcriptional repressor MngR YP_002925790.1 667136 R 595496 CDS YP_002925791.1 238899995 7953429 667967..669943 1 NC_012759.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 669943 mngA 7953429 mngA Escherichia coli BW2952 PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC YP_002925791.1 667967 D 595496 CDS YP_002925792.1 238899996 7953649 669961..672594 1 NC_012759.1 MG1655 equivalent: b0732; alpha-mannosidase 672594 mngB 7953649 mngB Escherichia coli BW2952 alpha-mannosidase YP_002925792.1 669961 D 595496 CDS YP_002925793.1 238899997 7952460 673441..675009 1 NC_012759.1 MG1655 equivalent: b0733; cytochrome d terminal oxidase, subunit I 675009 cydA 7952460 cydA Escherichia coli BW2952 cytochrome d terminal oxidase, subunit I YP_002925793.1 673441 D 595496 CDS YP_002925794.1 238899998 7953194 675025..676164 1 NC_012759.1 MG1655 equivalent: b0734; cytochrome d terminal oxidase, subunit II 676164 cydB 7953194 cydB Escherichia coli BW2952 cytochrome d terminal oxidase, subunit II YP_002925794.1 675025 D 595496 CDS YP_002925795.1 238899999 7953195 676179..676292 1 NC_012759.1 MG1655 equivalent: b4515; hypothetical protein 676292 ybgT 7953195 ybgT Escherichia coli BW2952 hypothetical protein YP_002925795.1 676179 D 595496 CDS YP_002925796.1 238900000 7953072 676292..676585 1 NC_012759.1 MG1655 equivalent: b0735; hypothetical protein 676585 ybgE 7953072 ybgE Escherichia coli BW2952 hypothetical protein YP_002925796.1 676292 D 595496 CDS YP_002925797.1 238900001 7952700 676735..677139 1 NC_012759.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 677139 ybgC 7952700 ybgC Escherichia coli BW2952 acyl-CoA thioester hydrolase YbgC YP_002925797.1 676735 D 595496 CDS YP_002925798.1 238900002 7954611 677136..677828 1 NC_012759.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 677828 tolQ 7954611 tolQ Escherichia coli BW2952 colicin uptake protein TolQ YP_002925798.1 677136 D 595496 CDS YP_002925799.1 238900003 7954233 677832..678260 1 NC_012759.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 678260 tolR 7954233 tolR Escherichia coli BW2952 colicin uptake protein TolR YP_002925799.1 677832 D 595496 CDS YP_002925800.1 238900004 7954234 678325..679590 1 NC_012759.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 679590 tolA 7954234 tolA Escherichia coli BW2952 cell envelope integrity inner membrane protein TolA YP_002925800.1 678325 D 595496 CDS YP_002925801.1 238900005 7954222 679723..681015 1 NC_012759.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 681015 tolB 7954222 tolB Escherichia coli BW2952 translocation protein TolB YP_002925801.1 679723 D 595496 CDS YP_002925802.1 238900006 7954494 681050..681571 1 NC_012759.1 MG1655 equivalent: b0741; peptidoglycan-associated outer membrane lipoprotein 681571 pal 7954494 pal Escherichia coli BW2952 peptidoglycan-associated outer membrane lipoprotein YP_002925802.1 681050 D 595496 CDS YP_002925803.1 238900007 7954478 681581..682372 1 NC_012759.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 682372 ybgF 7954478 ybgF Escherichia coli BW2952 tol-pal system protein YbgF YP_002925803.1 681581 D 595496 CDS YP_002925804.1 238900008 7952129 684276..685319 1 NC_012759.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 685319 nadA 7952129 nadA Escherichia coli BW2952 quinolinate synthetase YP_002925804.1 684276 D 595496 CDS YP_002925805.1 238900009 7955888 685357..686076 1 NC_012759.1 MG1655 equivalent: b0751; putative nicotinamide mononucleotide transporter 686076 pnuC 7955888 pnuC Escherichia coli BW2952 putative nicotinamide mononucleotide transporter YP_002925805.1 685357 D 595496 CDS YP_002925806.1 238900010 7955182 complement(686073..687014) 1 NC_012759.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 687014 zitB 7955182 zitB Escherichia coli BW2952 zinc transporter ZitB YP_002925806.1 686073 R 595496 CDS YP_002925807.1 238900011 7956282 complement(687128..687508) 1 NC_012759.1 MG1655 equivalent: b0753; hypothetical protein 687508 ybgS 7956282 ybgS Escherichia coli BW2952 hypothetical protein YP_002925807.1 687128 R 595496 CDS YP_002925808.1 238900012 7952774 687824..688876 1 NC_012759.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 688876 aroG 7952774 aroG Escherichia coli BW2952 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002925808.1 687824 D 595496 CDS YP_002925809.1 238900013 7952297 complement(689034..689786) 1 NC_012759.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 689786 gpmA 7952297 gpmA Escherichia coli BW2952 phosphoglyceromutase YP_002925809.1 689034 R 595496 CDS YP_002925810.1 238900014 7954536 complement(689988..691028) 1 NC_012759.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 691028 galM 7954536 galM Escherichia coli BW2952 aldose 1-epimerase YP_002925810.1 689988 R 595496 CDS YP_002925811.1 238900015 7953761 complement(691022..692170) 1 NC_012759.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 692170 galK 7953761 galK Escherichia coli BW2952 galactokinase YP_002925811.1 691022 R 595496 CDS YP_002925812.1 238900016 7953758 complement(692174..693220) 1 NC_012759.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 693220 galT 7953758 galT Escherichia coli BW2952 galactose-1-phosphate uridylyltransferase YP_002925812.1 692174 R 595496 CDS YP_002925813.1 238900017 7953762 complement(693230..694246) 1 NC_012759.1 MG1655 equivalent: b0759; UDP-galactose-4-epimerase 694246 galE 7953762 galE Escherichia coli BW2952 UDP-galactose-4-epimerase YP_002925813.1 693230 R 595496 CDS YP_002925814.1 238900018 7956232 complement(694507..695979) 1 NC_012759.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 695979 modF 7956232 modF Escherichia coli BW2952 putative molybdenum transport ATP-binding protein ModF YP_002925814.1 694507 R 595496 CDS YP_002925815.1 238900019 7953701 complement(696047..696835) 1 NC_012759.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 696835 modE 7953701 modE Escherichia coli BW2952 DNA-binding transcriptional regulator ModE YP_002925815.1 696047 R 595496 CDS YP_002925816.1 238900020 7953404 696964..697113 1 NC_012759.1 MG1655 equivalent: b0762; hypothetical protein 697113 ybhT 7953404 ybhT Escherichia coli BW2952 hypothetical protein YP_002925816.1 696964 D 595496 CDS YP_002925817.1 238900021 7955448 697280..698053 1 NC_012759.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 698053 modA 7955448 modA Escherichia coli BW2952 molybdate transporter periplasmic protein YP_002925817.1 697280 D 595496 CDS YP_002925818.1 238900022 7954283 698053..698742 1 NC_012759.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 698742 modB 7954283 modB Escherichia coli BW2952 molybdate ABC transporter permease YP_002925818.1 698053 D 595496 CDS YP_002925819.1 238900023 7954284 698745..699803 1 NC_012759.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 699803 modC 7954284 modC Escherichia coli BW2952 molybdate transporter ATP-binding protein YP_002925819.1 698745 D 595496 CDS YP_002925820.1 238900024 7954285 complement(699804..700622) 1 NC_012759.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 700622 ybhA 7954285 ybhA Escherichia coli BW2952 phosphotransferase YP_002925820.1 699804 R 595496 CDS YP_002925821.1 238900025 7954950 700777..701772 1 NC_012759.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 701772 pgl 7954950 pgl Escherichia coli BW2952 6-phosphogluconolactonase YP_002925821.1 700777 D 595496 CDS YP_002925822.1 238900026 7952380 complement(701813..702766) 1 NC_012759.1 MG1655 equivalent: b0768; putative DNA-binding transcriptional regulator 702766 ybhD 7952380 ybhD Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925822.1 701813 R 595496 CDS YP_002925823.1 238900027 7954749 702950..704002 1 NC_012759.1 MG1655 equivalent: b0769; hypothetical protein 704002 ybhH 7954749 ybhH Escherichia coli BW2952 hypothetical protein YP_002925823.1 702950 D 595496 CDS YP_002925824.1 238900028 7952937 704078..705511 1 NC_012759.1 MG1655 equivalent: b0770; putative transporter 705511 ybhI 7952937 ybhI Escherichia coli BW2952 putative transporter YP_002925824.1 704078 D 595496 CDS YP_002925825.1 238900029 7955681 705694..707955 1 NC_012759.1 MG1655 equivalent: b0771; hypothetical protein 707955 ybhJ 7955681 ybhJ Escherichia coli BW2952 hypothetical protein YP_002925825.1 705694 D 595496 CDS YP_002925826.1 238900030 7954947 complement(708189..709472) 1 NC_012759.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase 709472 ybhC 7954947 ybhC Escherichia coli BW2952 putative pectinesterase YP_002925826.1 708189 R 595496 CDS YP_002925827.1 238900031 7955269 complement(709624..710100) 1 NC_012759.1 YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein 710100 ybhB 7955269 ybhB Escherichia coli BW2952 putative kinase inhibitor protein YP_002925827.1 709624 R 595496 CDS YP_002925828.1 238900032 7955097 complement(710159..711448) 1 NC_012759.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 711448 bioA 7955097 bioA Escherichia coli BW2952 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002925828.1 710159 R 595496 CDS YP_002925829.1 238900033 7952382 711535..712575 1 NC_012759.1 MG1655 equivalent: b0775; biotin synthase 712575 bioB 7952382 bioB Escherichia coli BW2952 biotin synthase YP_002925829.1 711535 D 595496 CDS YP_002925830.1 238900034 7952582 712572..713726 1 NC_012759.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 713726 bioF 7952582 bioF Escherichia coli BW2952 8-amino-7-oxononanoate synthase YP_002925830.1 712572 D 595496 CDS YP_002925831.1 238900035 7952386 713713..714468 1 NC_012759.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 714468 bioC 7952386 bioC Escherichia coli BW2952 biotin biosynthesis protein BioC YP_002925831.1 713713 D 595496 CDS YP_002925832.1 238900036 7955149 714461..715138 1 NC_012759.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 715138 bioD 7955149 bioD Escherichia coli BW2952 dithiobiotin synthetase YP_002925832.1 714461 D 595496 CDS YP_002925833.1 238900037 7953241 complement(715305..715442) 1 NC_012759.1 MG1655 equivalent: b4591; hypothetical protein 715442 ybhU 7953241 ybhU Escherichia coli BW2952 hypothetical protein YP_002925833.1 715305 R 595496 CDS YP_002925834.1 238900038 7953963 715717..717738 1 NC_012759.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 717738 uvrB 7953963 uvrB Escherichia coli BW2952 excinuclease ABC subunit B YP_002925834.1 715717 D 595496 CDS YP_002925835.1 238900039 7953537 complement(717930..718838) 1 NC_012759.1 MG1655 equivalent: b0780; putative transferase with NAD(P)-binding Rossmann-fold domain 718838 ybhK 7953537 ybhK Escherichia coli BW2952 putative transferase with NAD(P)-binding Rossmann-fold domain YP_002925835.1 717930 R 595496 CDS YP_002925836.1 238900040 7955643 719235..720224 1 NC_012759.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 720224 moaA 7955643 moaA Escherichia coli BW2952 molybdenum cofactor biosynthesis protein A YP_002925836.1 719235 D 595496 CDS YP_002925837.1 238900041 7954288 720246..720758 1 NC_012759.1 MG1655 equivalent: b0782; molybdopterin biosynthesis protein B 720758 moaB 7954288 moaB Escherichia coli BW2952 molybdopterin biosynthesis protein B YP_002925837.1 720246 D 595496 CDS YP_002925838.1 238900042 7954289 720761..721246 1 NC_012759.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 721246 moaC 7954289 moaC Escherichia coli BW2952 molybdenum cofactor biosynthesis protein MoaC YP_002925838.1 720761 D 595496 CDS YP_002925839.1 238900043 7954290 721239..721484 1 NC_012759.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 721484 moaD 7954290 moaD Escherichia coli BW2952 molybdopterin synthase small subunit YP_002925839.1 721239 D 595496 CDS YP_002925840.1 238900044 7954293 721486..721938 1 NC_012759.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 721938 moaE 7954293 moaE Escherichia coli BW2952 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_002925840.1 721486 D 595496 CDS YP_002925841.1 238900045 7954292 722075..722779 1 NC_012759.1 MG1655 equivalent: b0786; putative inner membrane protein 722779 ybhL 7954292 ybhL Escherichia coli BW2952 putative inner membrane protein YP_002925841.1 722075 D 595496 CDS YP_002925842.1 238900046 7955027 722984..723697 1 NC_012759.1 MG1655 equivalent: b0787; hypothetical protein 723697 ybhM 7955027 ybhM Escherichia coli BW2952 hypothetical protein YP_002925842.1 722984 D 595496 CDS YP_002925843.1 238900047 7952701 complement(723733..724689) 1 NC_012759.1 MG1655 equivalent: b0788; hypothetical protein 724689 ybhN 7952701 ybhN Escherichia coli BW2952 hypothetical protein YP_002925843.1 723733 R 595496 CDS YP_002925844.1 238900048 7952666 complement(724689..725930) 1 NC_012759.1 MG1655 equivalent: b0789; cardiolipin synthase 2 725930 ybhO 7952666 ybhO Escherichia coli BW2952 cardiolipin synthase 2 YP_002925844.1 724689 R 595496 CDS YP_002925845.1 238900049 7952609 complement(725927..726688) 1 NC_012759.1 MG1655 equivalent: b0790; putative DNase 726688 ybhP 7952609 ybhP Escherichia coli BW2952 putative DNase YP_002925845.1 725927 R 595496 CDS YP_002925846.1 238900050 7954825 726821..727231 1 NC_012759.1 MG1655 equivalent: b0791; putative inner membrane protein 727231 ybhQ 7954825 ybhQ Escherichia coli BW2952 putative inner membrane protein YP_002925846.1 726821 D 595496 CDS YP_002925847.1 238900051 7955028 complement(727193..728299) 1 NC_012759.1 MG1655 equivalent: b0792; putative transporter subunit: membrane component of ABC superfamily 728299 ybhR 7955028 ybhR Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002925847.1 727193 R 595496 CDS YP_002925848.1 238900052 7955726 complement(728310..729443) 1 NC_012759.1 MG1655 equivalent: b0793; putative transporter subunit: membrane component of ABC superfamily 729443 ybhS 7955726 ybhS Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002925848.1 728310 R 595496 CDS YP_002925849.1 238900053 7955727 complement(729436..731172) 1 NC_012759.1 MG1655 equivalent: b0794; fused putative transporter subunits of ABC superfamily: ATP-binding components 731172 ybhF 7955727 ybhF Escherichia coli BW2952 fused putative transporter subunits of ABC superfamily: ATP-binding components YP_002925849.1 729436 R 595496 CDS YP_002925850.1 238900054 7953730 complement(731165..732163) 1 NC_012759.1 MG1655 equivalent: b0795; hypothetical protein 732163 ybhG 7953730 ybhG Escherichia coli BW2952 hypothetical protein YP_002925850.1 731165 R 595496 CDS YP_002925851.1 238900055 7955138 complement(732163..732834) 1 NC_012759.1 MG1655 equivalent: b0796; putative DNA-binding transcriptional regulator 732834 ybiH 7955138 ybiH Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925851.1 732163 R 595496 CDS YP_002925852.1 238900056 7954750 733063..734427 1 NC_012759.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 734427 rhlE 7954750 rhlE Escherichia coli BW2952 ATP-dependent RNA helicase RhlE YP_002925852.1 733063 D 595496 CDS YP_002925853.1 238900057 7955982 complement(734659..735141) 1 NC_012759.1 MG1655 equivalent: b0798; hypothetical protein 735141 ybiA 7955982 ybiA Escherichia coli BW2952 hypothetical protein YP_002925853.1 734659 R 595496 CDS YP_002925854.1 238900058 7952775 735261..737411 1 NC_012759.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 737411 dinG 7952775 dinG Escherichia coli BW2952 ATP-dependent DNA helicase DinG YP_002925854.1 735261 D 595496 CDS YP_002925855.1 238900059 7952529 737439..738401 1 NC_012759.1 MG1655 equivalent: b0800; glycosyl transferase family protein 738401 ybiB 7952529 ybiB Escherichia coli BW2952 glycosyl transferase family protein YP_002925855.1 737439 D 595496 CDS YP_002925856.1 238900060 7955644 738542..739627 1 NC_012759.1 MG1655 equivalent: b0801; hypothetical protein 739627 ybiC 7955644 ybiC Escherichia coli BW2952 hypothetical protein YP_002925856.1 738542 D 595496 CDS YP_002925857.1 238900061 7954714 complement(739856..740116) 1 NC_012759.1 MG1655 equivalent: b0802; hypothetical protein 740116 ybiJ 7954714 ybiJ Escherichia coli BW2952 hypothetical protein YP_002925857.1 739856 R 595496 CDS YP_002925858.1 238900062 7955341 complement(740381..740647) 1 NC_012759.1 MG1655 equivalent: b0803; hypothetical protein 740647 ybiI 7955341 ybiI Escherichia coli BW2952 hypothetical protein YP_002925858.1 740381 R 595496 CDS YP_002925859.1 238900063 7952776 complement(740721..741398) 1 NC_012759.1 MG1655 equivalent: b0804; putative hydroxylase 741398 ybiX 7952776 ybiX Escherichia coli BW2952 putative hydroxylase YP_002925859.1 740721 R 595496 CDS YP_002925860.1 238900064 7952777 complement(741440..743722) 1 NC_012759.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 743722 fiu 7952777 fiu Escherichia coli BW2952 catecholate siderophore receptor Fiu YP_002925860.1 741440 R 595496 CDS YP_002925861.1 238900065 7955087 complement(743987..744247) 1 NC_012759.1 MG1655 equivalent: b0806; hypothetical protein 744247 ybiM 7955087 ybiM Escherichia coli BW2952 hypothetical protein YP_002925861.1 743987 R 595496 CDS YP_002925862.1 238900066 7955342 744523..745449 1 NC_012759.1 MG1655 equivalent: b0807; putative SAM-dependent methyltransferase 745449 rlmF 7955342 rlmF Escherichia coli BW2952 putative SAM-dependent methyltransferase YP_002925862.1 744523 D 595496 CDS YP_002925863.1 238900067 7955583 complement(745446..747671) 1 NC_012759.1 MG1655 equivalent: b0808; hypothetical protein 747671 ybiO 7955583 ybiO Escherichia coli BW2952 hypothetical protein YP_002925863.1 745446 R 595496 CDS YP_002925864.1 238900068 7955136 complement(747932..748654) 1 NC_012759.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 748654 glnQ 7955136 glnQ Escherichia coli BW2952 glutamine ABC transporter ATP-binding protein YP_002925864.1 747932 R 595496 CDS YP_002925865.1 238900069 7953828 complement(748651..749310) 1 NC_012759.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 749310 glnP 7953828 glnP Escherichia coli BW2952 glutamine ABC transporter permease YP_002925865.1 748651 R 595496 CDS YP_002925866.1 238900070 7953829 complement(749449..750195) 1 NC_012759.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 750195 glnH 7953829 glnH Escherichia coli BW2952 glutamine ABC transporter periplasmic protein YP_002925866.1 749449 R 595496 CDS YP_002925867.1 238900071 7953830 complement(750599..751102) 1 NC_012759.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 751102 dps 7953830 dps Escherichia coli BW2952 DNA starvation/stationary phase protection protein Dps YP_002925867.1 750599 R 595496 CDS YP_002925868.1 238900072 7953562 complement(751401..752288) 1 NC_012759.1 MG1655 equivalent: b0813; threonine and homoserine efflux system 752288 rhtA 7953562 rhtA Escherichia coli BW2952 threonine and homoserine efflux system YP_002925868.1 751401 R 595496 CDS YP_002925869.1 238900073 7956143 752641..753156 1 NC_012759.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 753156 ompX 7956143 ompX Escherichia coli BW2952 outer membrane protein X YP_002925869.1 752641 D 595496 CDS YP_002925870.1 238900074 7954447 complement(753205..754788) 1 NC_012759.1 MG1655 equivalent: b0815; putative hydrolase, inner membrane 754788 ybiP 7954447 ybiP Escherichia coli BW2952 putative hydrolase, inner membrane YP_002925870.1 753205 R 595496 CDS YP_002925871.1 238900075 7954977 754862..755131 1 NC_012759.1 MG1655 equivalent: b0816; hypothetical protein 755131 yliL 7954977 yliL Escherichia coli BW2952 hypothetical protein YP_002925871.1 754862 D 595496 CDS YP_002925872.1 238900076 7952078 755374..755841 1 NC_012759.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 755841 mntR 7952078 mntR Escherichia coli BW2952 manganese transport regulator MntR YP_002925872.1 755374 D 595496 CDS YP_002925873.1 238900077 7953445 755838..756956 1 NC_012759.1 MG1655 equivalent: b0818; putative transporter 756956 ybiR 7953445 ybiR Escherichia coli BW2952 putative transporter YP_002925873.1 755838 D 595496 CDS YP_002925874.1 238900078 7955682 complement(757015..757935) 1 NC_012759.1 MG1655 equivalent: b0819; hypothetical protein 757935 ybiS 7955682 ybiS Escherichia coli BW2952 hypothetical protein YP_002925874.1 757015 R 595496 CDS YP_002925875.1 238900079 7952778 758154..759746 1 NC_012759.1 MG1655 equivalent: b0820; fused putative transporter subunits of ABC superfamily: ATP-binding components 759746 ybiT 7952778 ybiT Escherichia coli BW2952 fused putative transporter subunits of ABC superfamily: ATP-binding components YP_002925875.1 758154 D 595496 CDS YP_002925876.1 238900080 7953732 complement(759987..761252) 1 NC_012759.1 MG1655 equivalent: b0821; hypothetical protein 761252 ybiU 7953732 ybiU Escherichia coli BW2952 hypothetical protein YP_002925876.1 759987 R 595496 CDS YP_002925877.1 238900081 7955343 complement(761404..762219) 1 NC_012759.1 MG1655 equivalent: b0822; putative hydrolase 762219 ybiV 7955343 ybiV Escherichia coli BW2952 putative hydrolase YP_002925877.1 761404 R 595496 CDS YP_002925878.1 238900082 7954951 complement(762365..764797) 1 NC_012759.1 MG1655 equivalent: b0823; putative pyruvate formate lyase 764797 ybiW 7954951 ybiW Escherichia coli BW2952 putative pyruvate formate lyase YP_002925878.1 762365 R 595496 CDS YP_002925879.1 238900083 7955550 complement(764803..765729) 1 NC_012759.1 MG1655 equivalent: b0824; putative pyruvate formate lyase activating enzyme 765729 ybiY 7955550 ybiY Escherichia coli BW2952 putative pyruvate formate lyase activating enzyme YP_002925879.1 764803 R 595496 CDS YP_002925880.1 238900084 7955551 765833..766495 1 NC_012759.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 766495 fsaA 7955551 fsaA Escherichia coli BW2952 fructose-6-phosphate aldolase YP_002925880.1 765833 D 595496 CDS YP_002925881.1 238900085 7953635 complement(766571..767320) 1 NC_012759.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 767320 moeB 7953635 moeB Escherichia coli BW2952 molybdopterin biosynthesis protein MoeB YP_002925881.1 766571 R 595496 CDS YP_002925882.1 238900086 7954291 complement(767320..768555) 1 NC_012759.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 768555 moeA 7954291 moeA Escherichia coli BW2952 molybdopterin biosynthesis protein MoeA YP_002925882.1 767320 R 595496 CDS YP_002925883.1 238900087 7954287 768759..769724 1 NC_012759.1 MG1655 equivalent: b0828; L-asparaginase 769724 iaaA 7954287 iaaA Escherichia coli BW2952 L-asparaginase YP_002925883.1 768759 D 595496 CDS YP_002925884.1 238900088 7954120 769711..771582 1 NC_012759.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 771582 gsiA 7954120 gsiA Escherichia coli BW2952 glutathione transporter ATP-binding protein YP_002925884.1 769711 D 595496 CDS YP_002925885.1 238900089 7953722 771602..773140 1 NC_012759.1 MG1655 equivalent: b0830; putative peptide transporter subunit: periplasmic-binding component of ABC superfamily 773140 gsiB 7953722 gsiB Escherichia coli BW2952 putative peptide transporter subunit: periplasmic-binding component of ABC superfamily YP_002925885.1 771602 D 595496 CDS YP_002925886.1 238900090 7955295 773158..774078 1 NC_012759.1 MG1655 equivalent: b0831; putative peptide transporter subunit: membrane component of ABC superfamily 774078 gsiC 7955295 gsiC Escherichia coli BW2952 putative peptide transporter subunit: membrane component of ABC superfamily YP_002925886.1 773158 D 595496 CDS YP_002925887.1 238900091 7955293 774081..774992 1 NC_012759.1 MG1655 equivalent: b0832; putative peptide transporter subunit: membrane component of ABC superfamily 774992 gsiD 7955293 gsiD Escherichia coli BW2952 putative peptide transporter subunit: membrane component of ABC superfamily YP_002925887.1 774081 D 595496 CDS YP_002925888.1 238900092 7955294 775170..777518 1 NC_012759.1 MG1655 equivalent: b0833; hypothetical protein 777518 yliE 7955294 yliE Escherichia coli BW2952 hypothetical protein YP_002925888.1 775170 D 595496 CDS YP_002925889.1 238900093 7952702 777526..778854 1 NC_012759.1 MG1655 equivalent: b0834; putative diguanylate cyclase 778854 yliF 7952702 yliF Escherichia coli BW2952 putative diguanylate cyclase YP_002925889.1 777526 D 595496 CDS YP_002925890.1 238900094 7954727 complement(778901..780226) 1 NC_012759.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 780226 rimO 7954727 rimO Escherichia coli BW2952 ribosomal protein S12 methylthiotransferase YP_002925890.1 778901 R 595496 CDS YP_002925891.1 238900095 7955581 780439..780822 1 NC_012759.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 780822 bssR 7955581 bssR Escherichia coli BW2952 biofilm formation regulatory protein BssR YP_002925891.1 780439 D 595496 CDS YP_002925892.1 238900096 7952938 780933..782048 1 NC_012759.1 MG1655 equivalent: b0837; putative dehydrogenase 782048 yliI 7952938 yliI Escherichia coli BW2952 putative dehydrogenase YP_002925892.1 780933 D 595496 CDS YP_002925893.1 238900097 7954715 complement(782045..782671) 1 NC_012759.1 MG1655 equivalent: b0838; putative glutathione S-transferase 782671 yliJ 7954715 yliJ Escherichia coli BW2952 putative glutathione S-transferase YP_002925893.1 782045 R 595496 CDS YP_002925894.1 238900098 7954926 782918..784120 1 NC_012759.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 784120 dacC 7954926 dacC Escherichia coli BW2952 D-alanyl-D-alanine carboxypeptidase YP_002925894.1 782918 D 595496 CDS YP_002925895.1 238900099 7953219 complement(784167..784925) 1 NC_012759.1 MG1655 equivalent: b0840; DNA-binding transcriptional repressor DeoR 784925 deoR 7953219 deoR Escherichia coli BW2952 DNA-binding transcriptional repressor DeoR YP_002925895.1 784167 R 595496 CDS YP_002925896.1 238900100 7953449 complement(784983..785579) 1 NC_012759.1 MG1655 equivalent: b0841; UDP pyrophosphate phosphatase 785579 ybjG 7953449 ybjG Escherichia coli BW2952 UDP pyrophosphate phosphatase YP_002925896.1 784983 R 595496 CDS YP_002925897.1 238900101 7956248 785864..787096 1 NC_012759.1 MG1655 equivalent: b0842; multidrug efflux system protein 787096 cmr 7956248 cmr Escherichia coli BW2952 multidrug efflux system protein YP_002925897.1 785864 D 595496 CDS YP_002925898.1 238900102 7954301 complement(787137..787421) 1 NC_012759.1 MG1655 equivalent: b0843; hypothetical protein 787421 ybjH 7954301 ybjH Escherichia coli BW2952 hypothetical protein YP_002925898.1 787137 R 595496 CDS YP_002925899.1 238900103 7955344 complement(787507..788322) 1 NC_012759.1 MG1655 equivalent: b0844; hypothetical protein 788322 ybjI 7955344 ybjI Escherichia coli BW2952 hypothetical protein YP_002925899.1 787507 R 595496 CDS YP_002925900.1 238900104 7952779 complement(788322..789530) 1 NC_012759.1 MG1655 equivalent: b0845; putative transporter 789530 ybjJ 7952779 ybjJ Escherichia coli BW2952 putative transporter YP_002925900.1 788322 R 595496 CDS YP_002925901.1 238900105 7955651 789614..790150 1 NC_012759.1 MG1655 equivalent: b0846; putative DNA-binding transcriptional regulator 790150 ybjK 7955651 ybjK Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925901.1 789614 D 595496 CDS YP_002925902.1 238900106 7952079 complement(790325..792010) 1 NC_012759.1 MG1655 equivalent: b0847; hypothetical protein 792010 ybjL 7952079 ybjL Escherichia coli BW2952 hypothetical protein YP_002925902.1 790325 R 595496 CDS YP_002925903.1 238900107 7955652 792280..792657 1 NC_012759.1 MG1655 equivalent: b0848; putative inner membrane protein 792657 ybjM 7955652 ybjM Escherichia coli BW2952 putative inner membrane protein YP_002925903.1 792280 D 595496 CDS YP_002925904.1 238900108 7955029 complement(792687..792944) 1 NC_012759.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 792944 grxA 7955029 grxA Escherichia coli BW2952 glutaredoxin YP_002925904.1 792687 R 595496 CDS YP_002925905.1 238900109 7953835 793104..793391 1 NC_012759.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 793391 ybjC 7953835 ybjC Escherichia coli BW2952 hypothetical protein YP_002925905.1 793104 D 595496 CDS YP_002925906.1 238900110 7955030 793375..794097 1 NC_012759.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 794097 nfsA 7955030 nfsA Escherichia coli BW2952 nitroreductase A YP_002925906.1 793375 D 595496 CDS YP_002925907.1 238900111 7954405 794158..795060 1 NC_012759.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 795060 rimK 7954405 rimK Escherichia coli BW2952 ribosomal protein S6 modification protein YP_002925907.1 794158 D 595496 CDS YP_002925908.1 238900112 7955974 795148..795624 1 NC_012759.1 MG1655 equivalent: b0853; putative oxidoreductase 795624 ybjN 7955974 ybjN Escherichia coli BW2952 putative oxidoreductase YP_002925908.1 795148 D 595496 CDS YP_002925909.1 238900113 7955231 795975..797087 1 NC_012759.1 MG1655 equivalent: b0854; putrescine ABC transporter periplasmic-binding protein 797087 potF 7955231 potF Escherichia coli BW2952 putrescine ABC transporter periplasmic-binding protein YP_002925909.1 795975 D 595496 CDS YP_002925910.1 238900114 7955831 797182..798315 1 NC_012759.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 798315 potG 7955831 potG Escherichia coli BW2952 putrescine ABC transporter ATP-binding protein YP_002925910.1 797182 D 595496 CDS YP_002925911.1 238900115 7955828 798325..799278 1 NC_012759.1 MG1655 equivalent: b0856; putrescine ABC transporter membrane protein 799278 potH 7955828 potH Escherichia coli BW2952 putrescine ABC transporter membrane protein YP_002925911.1 798325 D 595496 CDS YP_002925912.1 238900116 7955829 799275..800120 1 NC_012759.1 MG1655 equivalent: b0857; putrescine ABC transporter membrane protein 800120 potI 7955829 potI Escherichia coli BW2952 putrescine ABC transporter membrane protein YP_002925912.1 799275 D 595496 CDS YP_002925913.1 238900117 7955830 800180..800668 1 NC_012759.1 MG1655 equivalent: b0858; putative inner membrane protein 800668 ybjO 7955830 ybjO Escherichia coli BW2952 putative inner membrane protein YP_002925913.1 800180 D 595496 CDS YP_002925914.1 238900118 7955031 800709..801836 1 NC_012759.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 801836 rumB 7955031 rumB Escherichia coli BW2952 23S rRNA methyluridine methyltransferase YP_002925914.1 800709 D 595496 CDS YP_002925915.1 238900119 7952243 complement(802035..802766) 1 NC_012759.1 MG1655 equivalent: b0860; arginine transporter subunit 802766 artJ 7952243 artJ Escherichia coli BW2952 arginine transporter subunit YP_002925915.1 802035 R 595496 CDS YP_002925916.1 238900120 7952495 complement(803057..803725) 1 NC_012759.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 803725 artM 7952495 artM Escherichia coli BW2952 arginine transporter permease subunit ArtM YP_002925916.1 803057 R 595496 CDS YP_002925917.1 238900121 7952496 complement(803725..804441) 1 NC_012759.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 804441 artQ 7952496 artQ Escherichia coli BW2952 arginine transporter permease subunit ArtQ YP_002925917.1 803725 R 595496 CDS YP_002925918.1 238900122 7952497 complement(804448..805179) 1 NC_012759.1 MG1655 equivalent: b0863; arginine transporter subunit 805179 artI 7952497 artI Escherichia coli BW2952 arginine transporter subunit YP_002925918.1 804448 R 595496 CDS YP_002925919.1 238900123 7952498 complement(805197..805925) 1 NC_012759.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 805925 artP 7952498 artP Escherichia coli BW2952 arginine transporter ATP-binding subunit YP_002925919.1 805197 R 595496 CDS YP_002925920.1 238900124 7952499 complement(806143..806658) 1 NC_012759.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein 806658 ybjP 7952499 ybjP Escherichia coli BW2952 putative lipoprotein YP_002925920.1 806143 R 595496 CDS YP_002925921.1 238900125 7955105 806784..807107 1 NC_012759.1 MG1655 equivalent: b0866; hypothetical protein 807107 ybjQ 7955105 ybjQ Escherichia coli BW2952 hypothetical protein YP_002925921.1 806784 D 595496 CDS YP_002925922.1 238900126 7952939 807104..807934 1 NC_012759.1 MG1655 equivalent: b0867; putative amidase and lipoprotein 807934 amiD 7952939 amiD Escherichia coli BW2952 putative amidase and lipoprotein YP_002925922.1 807104 D 595496 CDS YP_002925923.1 238900127 7954637 complement(807931..808944) 1 NC_012759.1 MG1655 equivalent: b0868; putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain 808944 ybjS 7954637 ybjS Escherichia coli BW2952 putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain YP_002925923.1 807931 R 595496 CDS YP_002925924.1 238900128 7955181 complement(809043..810473) 1 NC_012759.1 MG1655 equivalent: b0869; hypothetical protein 810473 ybjT 7955181 ybjT Escherichia coli BW2952 hypothetical protein YP_002925924.1 809043 R 595496 CDS YP_002925925.1 238900129 7953080 complement(810484..811485) 1 NC_012759.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 811485 ltaE 7953080 ltaE Escherichia coli BW2952 L-threonine aldolase YP_002925925.1 810484 R 595496 CDS YP_002925926.1 238900130 7954109 complement(811522..813240) 1 NC_012759.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 813240 poxB 7954109 poxB Escherichia coli BW2952 pyruvate dehydrogenase YP_002925926.1 811522 R 595496 CDS YP_002925927.1 238900131 7955844 complement(813373..814341) 1 NC_012759.1 MG1655 equivalent: b0872; HCP oxidoreductase 814341 hcr 7955844 hcr Escherichia coli BW2952 HCP oxidoreductase YP_002925927.1 813373 R 595496 CDS YP_002925928.1 238900132 7953888 complement(814353..816005) 1 NC_012759.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 816005 hcp 7953888 hcp Escherichia coli BW2952 hydroxylamine reductase YP_002925928.1 814353 R 595496 CDS YP_002925929.1 238900133 7953933 complement(816149..817048) 1 NC_012759.1 MG1655 equivalent: b0874; putative transporter 817048 ybjE 7953933 ybjE Escherichia coli BW2952 putative transporter YP_002925929.1 816149 R 595496 CDS YP_002925930.1 238900134 7955653 complement(817543..818238) 1 NC_012759.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 818238 aqpZ 7955653 aqpZ Escherichia coli BW2952 aquaporin Z YP_002925930.1 817543 R 595496 CDS YP_002925931.1 238900135 7952491 818664..820322 1 NC_012759.1 MG1655 equivalent: b0876; hypothetical protein 820322 ybjD 7952491 ybjD Escherichia coli BW2952 hypothetical protein YP_002925931.1 818664 D 595496 CDS YP_002925932.1 238900136 7953088 complement(820319..821311) 1 NC_012759.1 MG1655 equivalent: b0877; hypothetical protein 821311 ybjX 7953088 ybjX Escherichia coli BW2952 hypothetical protein YP_002925932.1 820319 R 595496 CDS YP_002925933.1 238900137 7952780 821426..822541 1 NC_012759.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 822541 macA 7952780 macA Escherichia coli BW2952 macrolide transporter subunit MacA YP_002925933.1 821426 D 595496 CDS YP_002925934.1 238900138 7954190 822538..824484 1 NC_012759.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 824484 macB 7954190 macB Escherichia coli BW2952 macrolide transporter ATP-binding /permease YP_002925934.1 822538 D 595496 CDS YP_002925935.1 238900139 7953694 complement(824557..824781) 1 NC_012759.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 824781 cspD 7953694 cspD Escherichia coli BW2952 stationary phase/starvation inducible regulatory protein CspD YP_002925935.1 824557 R 595496 CDS YP_002925936.1 238900140 7952654 825104..825424 1 NC_012759.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 825424 clpS 7952654 clpS Escherichia coli BW2952 ATP-dependent Clp protease adaptor protein ClpS YP_002925936.1 825104 D 595496 CDS YP_002925937.1 238900141 7955931 825455..827731 1 NC_012759.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 827731 clpA 7955931 clpA Escherichia coli BW2952 ATP-dependent Clp protease ATP-binding subunit YP_002925937.1 825455 D 595496 CDS YP_002925938.1 238900142 7952048 complement(828416..828634) 1 NC_012759.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 828634 infA 7952048 infA Escherichia coli BW2952 translation initiation factor IF-1 YP_002925938.1 828416 R 595496 CDS YP_002925939.1 238900143 7956176 complement(828919..829623) 1 NC_012759.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 829623 aat 7956176 aat Escherichia coli BW2952 leucyl/phenylalanyl-tRNA--protein transferase YP_002925939.1 828919 R 595496 CDS YP_002925940.1 238900144 7954131 complement(829665..831386) 1 NC_012759.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 831386 cydC 7954131 cydC Escherichia coli BW2952 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002925940.1 829665 R 595496 CDS YP_002925941.1 238900145 7953668 complement(831387..833153) 1 NC_012759.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 833153 cydD 7953668 cydD Escherichia coli BW2952 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002925941.1 831387 R 595496 CDS YP_002925942.1 238900146 7953669 complement(833276..834241) 1 NC_012759.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 834241 trxB 7953669 trxB Escherichia coli BW2952 thioredoxin reductase YP_002925942.1 833276 R 595496 CDS YP_002925943.1 238900147 7956136 834786..835280 1 NC_012759.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 835280 lrp 7956136 lrp Escherichia coli BW2952 leucine-responsive transcriptional regulator YP_002925943.1 834786 D 595496 CDS YP_002925944.1 238900148 7953434 835415..839404 1 NC_012759.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 839404 ftsK 7953434 ftsK Escherichia coli BW2952 DNA translocase FtsK YP_002925944.1 835415 D 595496 CDS YP_002925945.1 238900149 7953339 839563..840174 1 NC_012759.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 840174 lolA 7953339 lolA Escherichia coli BW2952 outer-membrane lipoprotein carrier protein YP_002925945.1 839563 D 595496 CDS YP_002925946.1 238900150 7952626 840185..841528 1 NC_012759.1 MG1655 equivalent: b0892; recombination factor protein RarA 841528 rarA 7952626 rarA Escherichia coli BW2952 recombination factor protein RarA YP_002925946.1 840185 D 595496 CDS YP_002925947.1 238900151 7955916 841619..842911 1 NC_012759.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 842911 serS 7955916 serS Escherichia coli BW2952 seryl-tRNA synthetase YP_002925947.1 841619 D 595496 CDS YP_002925948.1 238900152 7956036 843150..845594 1 NC_012759.1 MG1655 equivalent: b0894; dimethyl sulfoxide reductase, anaerobic subunit A 845594 dmsA 7956036 dmsA Escherichia coli BW2952 dimethyl sulfoxide reductase, anaerobic subunit A YP_002925948.1 843150 D 595496 CDS YP_002925949.1 238900153 7953261 845605..846222 1 NC_012759.1 MG1655 equivalent: b0895; dimethyl sulfoxide reductase, anaerobic subunit B 846222 dmsB 7953261 dmsB Escherichia coli BW2952 dimethyl sulfoxide reductase, anaerobic subunit B YP_002925949.1 845605 D 595496 CDS YP_002925950.1 238900154 7953262 846224..847087 1 NC_012759.1 MG1655 equivalent: b0896; dimethyl sulfoxide reductase, anaerobic subunit C 847087 dmsC 7953262 dmsC Escherichia coli BW2952 dimethyl sulfoxide reductase, anaerobic subunit C YP_002925950.1 846224 D 595496 CDS YP_002925951.1 238900155 7953263 complement(847122..847748) 1 NC_012759.1 MG1655 equivalent: b0897; putative hydrolase 847748 ycaC 7953263 ycaC Escherichia coli BW2952 putative hydrolase YP_002925951.1 847122 R 595496 CDS YP_002925952.1 238900156 7954952 848062..849210 1 NC_012759.1 MG1655 equivalent: b0898; putative MFS family transporter protein 849210 ycaD 7954952 ycaD Escherichia coli BW2952 putative MFS family transporter protein YP_002925952.1 848062 D 595496 CDS YP_002925953.1 238900157 7955683 849420..850850 1 NC_012759.1 MG1655 equivalent: b0899; putative transporter 850850 ycaM 7955683 ycaM Escherichia coli BW2952 putative transporter YP_002925953.1 849420 D 595496 CDS YP_002925954.1 238900158 7955684 complement(850851..851759) 1 NC_012759.1 MG1655 equivalent: b0900; putative DNA-binding transcriptional regulator 851759 ycaN 7955684 ycaN Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002925954.1 850851 R 595496 CDS YP_002925955.1 238900159 7954751 851859..852449 1 NC_012759.1 MG1655 equivalent: b0901; hypothetical protein 852449 ycaK 7954751 ycaK Escherichia coli BW2952 hypothetical protein YP_002925955.1 851859 D 595496 CDS YP_002925956.1 238900160 7952940 complement(852531..853271) 1 NC_012759.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 853271 pflA 7952940 pflA Escherichia coli BW2952 pyruvate formate lyase-activating enzyme 1 YP_002925956.1 852531 R 595496 CDS YP_002925957.1 238900161 7955847 complement(853463..855745) 1 NC_012759.1 MG1655 equivalent: b0903; pyruvate formate lyase I 855745 pflB 7955847 pflB Escherichia coli BW2952 pyruvate formate lyase I YP_002925957.1 853463 R 595496 CDS YP_002925958.1 238900162 7955848 complement(855800..856657) 1 NC_012759.1 MG1655 equivalent: b0904; formate transporter 856657 focA 7955848 focA Escherichia coli BW2952 formate transporter YP_002925958.1 855800 R 595496 CDS YP_002925959.1 238900163 7953626 complement(857063..858823) 1 NC_012759.1 MG1655 equivalent: b0905; hypothetical protein 858823 ycaO 7953626 ycaO Escherichia coli BW2952 hypothetical protein YP_002925959.1 857063 R 595496 CDS YP_002925960.1 238900164 7952781 858953..859645 1 NC_012759.1 MG1655 equivalent: b0906; hypothetical protein 859645 ycaP 7952781 ycaP Escherichia coli BW2952 hypothetical protein YP_002925960.1 858953 D 595496 CDS YP_002925961.1 238900165 7952703 859844..860932 1 NC_012759.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 860932 serC 7952703 serC Escherichia coli BW2952 phosphoserine aminotransferase YP_002925961.1 859844 D 595496 CDS YP_002925962.1 238900166 7952326 861003..862286 1 NC_012759.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 862286 aroA 7952326 aroA Escherichia coli BW2952 3-phosphoshikimate 1-carboxyvinyltransferase YP_002925962.1 861003 D 595496 CDS YP_002925963.1 238900167 7952370 862455..863219 1 NC_012759.1 MG1655 equivalent: b0909; putative peptidase with chaperone function 863219 ycaL 7952370 ycaL Escherichia coli BW2952 putative peptidase with chaperone function YP_002925963.1 862455 D 595496 CDS YP_002925964.1 238900168 7955289 863392..864075 1 NC_012759.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 864075 cmk 7955289 cmk Escherichia coli BW2952 cytidylate kinase YP_002925964.1 863392 D 595496 CDS YP_002925965.1 238900169 7953189 864186..865859 1 NC_012759.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 865859 rpsA 7953189 rpsA Escherichia coli BW2952 30S ribosomal protein S1 YP_002925965.1 864186 D 595496 CDS YP_002925966.1 238900170 7952272 866019..866303 1 NC_012759.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 866303 ihfB 7952272 ihfB Escherichia coli BW2952 integration host factor subunit beta YP_002925966.1 866019 D 595496 CDS YP_002925967.1 238900171 7954011 866511..868775 1 NC_012759.1 MG1655 equivalent: b0913; hypothetical protein 868775 ycaI 7954011 ycaI Escherichia coli BW2952 hypothetical protein YP_002925967.1 866511 D 595496 CDS YP_002925968.1 238900172 7952704 868812..870560 1 NC_012759.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 870560 msbA 7952704 msbA Escherichia coli BW2952 lipid transporter ATP-binding/permease YP_002925968.1 868812 D 595496 CDS YP_002925969.1 238900173 7953693 870557..871543 1 NC_012759.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 871543 lpxK 7953693 lpxK Escherichia coli BW2952 tetraacyldisaccharide 4'-kinase YP_002925969.1 870557 D 595496 CDS YP_002925970.1 238900174 7954144 871580..872812 1 NC_012759.1 MG1655 equivalent: b0916; hypothetical protein 872812 ycaQ 7954144 ycaQ Escherichia coli BW2952 hypothetical protein YP_002925970.1 871580 D 595496 CDS YP_002925971.1 238900175 7952941 872864..873046 1 NC_012759.1 MG1655 equivalent: b0917; hypothetical protein 873046 ycaR 7952941 ycaR Escherichia coli BW2952 hypothetical protein YP_002925971.1 872864 D 595496 CDS YP_002925972.1 238900176 7952942 873043..873789 1 NC_012759.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 873789 kdsB 7952942 kdsB Escherichia coli BW2952 3-deoxy-manno-octulosonate cytidylyltransferase YP_002925972.1 873043 D 595496 CDS YP_002925973.1 238900177 7952303 873943..874836 1 NC_012759.1 MG1655 equivalent: b0919; hypothetical protein 874836 ycbJ 7952303 ycbJ Escherichia coli BW2952 hypothetical protein YP_002925973.1 873943 D 595496 CDS YP_002925974.1 238900178 7952943 complement(874813..875592) 1 NC_012759.1 MG1655 equivalent: b0920; hypothetical protein 875592 ycbC 7952943 ycbC Escherichia coli BW2952 hypothetical protein YP_002925974.1 874813 R 595496 CDS YP_002925975.1 238900179 7952667 875728..876513 1 NC_012759.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 876513 smtA 7952667 smtA Escherichia coli BW2952 putative metallothionein SmtA YP_002925975.1 875728 D 595496 CDS YP_002925976.1 238900180 7955578 876510..877832 1 NC_012759.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 877832 mukF 7955578 mukF Escherichia coli BW2952 condesin subunit F YP_002925976.1 876510 D 595496 CDS YP_002925977.1 238900181 7954012 877840..878517 1 NC_012759.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 878517 mukE 7954012 mukE Escherichia coli BW2952 condesin subunit E YP_002925977.1 877840 D 595496 CDS YP_002925978.1 238900182 7955793 878517..882977 1 NC_012759.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 882977 mukB 7955793 mukB Escherichia coli BW2952 cell division protein MukB YP_002925978.1 878517 D 595496 CDS YP_002925979.1 238900183 7953665 883238..885085 1 NC_012759.1 MG1655 equivalent: b0925; hypothetical protein 885085 ycbB 7953665 ycbB Escherichia coli BW2952 hypothetical protein YP_002925979.1 883238 D 595496 CDS YP_002925980.1 238900184 7954676 885266..885814 1 NC_012759.1 MG1655 equivalent: b0926; hypothetical protein 885814 ycbK 7954676 ycbK Escherichia coli BW2952 hypothetical protein YP_002925980.1 885266 D 595496 CDS YP_002925981.1 238900185 7952944 885841..886488 1 NC_012759.1 MG1655 equivalent: b0927; putative metal-binding enzyme 886488 ycbL 7952944 ycbL Escherichia coli BW2952 putative metal-binding enzyme YP_002925981.1 885841 D 595496 CDS YP_002925982.1 238900186 7955147 complement(886710..887900) 1 NC_012759.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 887900 aspC 7955147 aspC Escherichia coli BW2952 aromatic amino acid aminotransferase YP_002925982.1 886710 R 595496 CDS YP_002925983.1 238900187 7952511 complement(888085..889173) 1 NC_012759.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 889173 ompF 7952511 ompF Escherichia coli BW2952 outer membrane protein F YP_002925983.1 888085 R 595496 CDS YP_002925984.1 238900188 7954445 complement(889776..891176) 1 NC_012759.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 891176 asnC 7954445 asnC Escherichia coli BW2952 asparaginyl-tRNA synthetase YP_002925984.1 889776 R 595496 CDS YP_002925985.1 238900189 7952509 complement(891345..892547) 1 NC_012759.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 892547 pncB 7952509 pncB Escherichia coli BW2952 nicotinate phosphoribosyltransferase YP_002925985.1 891345 R 595496 CDS YP_002925986.1 238900190 7954383 892813..895425 1 NC_012759.1 MG1655 equivalent: b0932; aminopeptidase N 895425 pepN 7954383 pepN Escherichia coli BW2952 aminopeptidase N YP_002925986.1 892813 D 595496 CDS YP_002925987.1 238900191 7952473 complement(895468..896235) 1 NC_012759.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 896235 ssuB 7952473 ssuB Escherichia coli BW2952 aliphatic sulfonates transport ATP-binding subunit YP_002925987.1 895468 R 595496 CDS YP_002925988.1 238900192 7952447 complement(896232..897023) 1 NC_012759.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit 897023 ssuC 7952447 ssuC Escherichia coli BW2952 alkanesulfonate transporter permease subunit YP_002925988.1 896232 R 595496 CDS YP_002925989.1 238900193 7952448 complement(897034..898179) 1 NC_012759.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 898179 ssuD 7952448 ssuD Escherichia coli BW2952 alkanesulfonate monooxygenase YP_002925989.1 897034 R 595496 CDS YP_002925990.1 238900194 7952446 complement(898176..899135) 1 NC_012759.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 899135 ssuA 7952446 ssuA Escherichia coli BW2952 alkanesulfonate transporter substrate-binding subunit YP_002925990.1 898176 R 595496 CDS YP_002925991.1 238900195 7952449 complement(899128..899703) 1 NC_012759.1 MG1655 equivalent: b0937; NAD(P)H-dependent FMN reductase 899703 ssuE 7952449 ssuE Escherichia coli BW2952 NAD(P)H-dependent FMN reductase YP_002925991.1 899128 R 595496 CDS YP_002925992.1 238900196 7954352 900059..900598 1 NC_012759.1 MG1655 equivalent: b0938; putative fimbrial-like adhesin protein 900598 ycbQ 7954352 ycbQ Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925992.1 900059 D 595496 CDS YP_002925993.1 238900197 7954895 900681..901382 1 NC_012759.1 MG1655 equivalent: b0939; putative periplasmic pilin chaperone 901382 ycbR 7954895 ycbR Escherichia coli BW2952 putative periplasmic pilin chaperone YP_002925993.1 900681 D 595496 CDS YP_002925994.1 238900198 7955302 901407..904007 1 NC_012759.1 MG1655 equivalent: b0940; putative outer membrane usher protein 904007 ycbS 7955302 ycbS Escherichia coli BW2952 putative outer membrane usher protein YP_002925994.1 901407 D 595496 CDS YP_002925995.1 238900199 7955219 903998..905068 1 NC_012759.1 MG1655 equivalent: b0941; putative fimbrial-like adhesin protein 905068 ycbT 7955219 ycbT Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925995.1 903998 D 595496 CDS YP_002925996.1 238900200 7954896 905080..905622 1 NC_012759.1 MG1655 equivalent: b0942; putative fimbrial-like adhesin protein 905622 ycbU 7954896 ycbU Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925996.1 905080 D 595496 CDS YP_002925997.1 238900201 7954897 905630..906145 1 NC_012759.1 MG1655 equivalent: b0943; putative fimbrial-like adhesin protein 906145 ycbV 7954897 ycbV Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002925997.1 905630 D 595496 CDS YP_002925998.1 238900202 7954898 906138..906848 1 NC_012759.1 MG1655 equivalent: b0944; putativi pili assembly chaperone 906848 ycbF 7954898 ycbF Escherichia coli BW2952 putativi pili assembly chaperone YP_002925998.1 906138 D 595496 CDS YP_002925999.1 238900203 7955305 906959..907969 1 NC_012759.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 907969 pyrD 7955305 pyrD Escherichia coli BW2952 dihydroorotate dehydrogenase 2 YP_002925999.1 906959 D 595496 CDS YP_002926000.1 238900204 7953255 908143..908685 1 NC_012759.1 MG1655 equivalent: b0946; hypothetical protein 908685 ycbW 7953255 ycbW Escherichia coli BW2952 hypothetical protein YP_002926000.1 908143 D 595496 CDS YP_002926001.1 238900205 7955450 complement(908682..909791) 1 NC_012759.1 MG1655 equivalent: b0947; putative 2Fe-2S cluster-containing protein 909791 ycbX 7955450 ycbX Escherichia coli BW2952 putative 2Fe-2S cluster-containing protein YP_002926001.1 908682 R 595496 CDS YP_002926002.1 238900206 7954584 910035..912143 1 NC_012759.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 912143 rlmL 7954584 rlmL Escherichia coli BW2952 23S rRNA m(2)G2445 methyltransferase YP_002926002.1 910035 D 595496 CDS YP_002926003.1 238900207 7955157 912155..914062 1 NC_012759.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 914062 uup 7955157 uup Escherichia coli BW2952 ABC transporter ATPase YP_002926003.1 912155 D 595496 CDS YP_002926004.1 238900208 7953733 914192..915445 1 NC_012759.1 MG1655 equivalent: b0950; paraquat-inducible membrane protein A 915445 pqiA 7953733 pqiA Escherichia coli BW2952 paraquat-inducible membrane protein A YP_002926004.1 914192 D 595496 CDS YP_002926005.1 238900209 7954468 915450..917090 1 NC_012759.1 MG1655 equivalent: b0951; paraquat-inducible protein B 917090 pqiB 7954468 pqiB Escherichia coli BW2952 paraquat-inducible protein B YP_002926005.1 915450 D 595496 CDS YP_002926006.1 238900210 7954469 917087..917650 1 NC_012759.1 MG1655 equivalent: b0952; hypothetical protein 917650 ymbA 7954469 ymbA Escherichia coli BW2952 hypothetical protein YP_002926006.1 917087 D 595496 CDS YP_002926007.1 238900211 7952945 917906..918073 1 NC_012759.1 MG1655 equivalent: b0953; ribosome modulation factor 918073 rmf 7952945 rmf Escherichia coli BW2952 ribosome modulation factor YP_002926007.1 917906 D 595496 CDS YP_002926008.1 238900212 7955977 complement(918143..918661) 1 NC_012759.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 918661 fabA 7955977 fabA Escherichia coli BW2952 3-hydroxydecanoyl-ACP dehydratase YP_002926008.1 918143 R 595496 CDS YP_002926009.1 238900213 7952549 complement(918730..920490) 1 NC_012759.1 MG1655 equivalent: b0955; putative peptidase 920490 ycbZ 7952549 ycbZ Escherichia coli BW2952 putative peptidase YP_002926009.1 918730 R 595496 CDS YP_002926010.1 238900214 7955270 920676..921128 1 NC_012759.1 MG1655 equivalent: b0956; hypothetical protein 921128 ycbG 7955270 ycbG Escherichia coli BW2952 hypothetical protein YP_002926010.1 920676 D 595496 CDS YP_002926011.1 238900215 7952946 complement(921204..922244) 1 NC_012759.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 922244 ompA 7952946 ompA Escherichia coli BW2952 outer membrane protein A YP_002926011.1 921204 R 595496 CDS YP_002926012.1 238900216 7954448 complement(922601..923110) 1 NC_012759.1 MG1655 equivalent: b0958; SOS cell division inhibitor 923110 sulA 7954448 sulA Escherichia coli BW2952 SOS cell division inhibitor YP_002926012.1 922601 R 595496 CDS YP_002926013.1 238900217 7956059 923329..923958 1 NC_012759.1 MG1655 equivalent: b0959; hypothetical protein 923958 sxy 7956059 sxy Escherichia coli BW2952 hypothetical protein YP_002926013.1 923329 D 595496 CDS YP_002926014.1 238900218 7952947 complement(923921..926074) 1 NC_012759.1 MG1655 equivalent: b0960; putative inner membrane protein 926074 yccS 7952947 yccS Escherichia coli BW2952 putative inner membrane protein YP_002926014.1 923921 R 595496 CDS YP_002926015.1 238900219 7954988 complement(926093..926539) 1 NC_012759.1 MG1655 equivalent: b0961; hypothetical protein 926539 yccF 7954988 yccF Escherichia coli BW2952 hypothetical protein YP_002926015.1 926093 R 595496 CDS YP_002926016.1 238900220 7952668 926662..928716 1 NC_012759.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 928716 helD 7952668 helD Escherichia coli BW2952 DNA helicase IV YP_002926016.1 926662 D 595496 CDS YP_002926017.1 238900221 7953310 complement(928748..929206) 1 NC_012759.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 929206 mgsA 7953310 mgsA Escherichia coli BW2952 methylglyoxal synthase YP_002926017.1 928748 R 595496 CDS YP_002926018.1 238900222 7954259 complement(929302..929964) 1 NC_012759.1 MG1655 equivalent: b0964; hypothetical protein 929964 yccT 7954259 yccT Escherichia coli BW2952 hypothetical protein YP_002926018.1 929302 R 595496 CDS YP_002926019.1 238900223 7952782 930137..930550 1 NC_012759.1 MG1655 equivalent: b0965; putative CoA-binding protein with NAD(P)-binding Rossmann-fold domain 930550 yccU 7952782 yccU Escherichia coli BW2952 putative CoA-binding protein with NAD(P)-binding Rossmann-fold domain YP_002926019.1 930137 D 595496 CDS YP_002926020.1 238900224 7954696 complement(930595..930912) 1 NC_012759.1 MG1655 equivalent: b0966; heat shock protein HspQ 930912 hspQ 7954696 hspQ Escherichia coli BW2952 heat shock protein HspQ YP_002926020.1 930595 R 595496 CDS YP_002926021.1 238900225 7953340 complement(930970..932160) 1 NC_012759.1 MG1655 equivalent: b0967; putative methyltransferase 932160 yccW 7953340 yccW Escherichia coli BW2952 putative methyltransferase YP_002926021.1 930970 R 595496 CDS YP_002926022.1 238900226 7955152 932255..932533 1 NC_012759.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 932533 yccX 7955152 yccX Escherichia coli BW2952 acylphosphatase YP_002926022.1 932255 D 595496 CDS YP_002926023.1 238900227 7954612 complement(932530..932859) 1 NC_012759.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 932859 yccK 7954612 yccK Escherichia coli BW2952 sulfur transfer protein TusE YP_002926023.1 932530 R 595496 CDS YP_002926024.1 238900228 7955616 complement(932950..933609) 1 NC_012759.1 MG1655 equivalent: b0970; hypothetical protein 933609 yccA 7955616 yccA Escherichia coli BW2952 hypothetical protein YP_002926024.1 932950 R 595496 CDS YP_002926025.1 238900229 7952049 934330..935448 1 NC_012759.1 MG1655 equivalent: b0972; hydrogenase 1, small subunit 935448 hyaA 7952049 hyaA Escherichia coli BW2952 hydrogenase 1, small subunit YP_002926025.1 934330 D 595496 CDS YP_002926026.1 238900230 7953937 935445..937238 1 NC_012759.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 937238 hyaB 7953937 hyaB Escherichia coli BW2952 hydrogenase 1 large subunit YP_002926026.1 935445 D 595496 CDS YP_002926027.1 238900231 7953936 937257..937964 1 NC_012759.1 MG1655 equivalent: b0974; hydrogenase 1 b-type cytochrome subunit 937964 hyaC 7953936 hyaC Escherichia coli BW2952 hydrogenase 1 b-type cytochrome subunit YP_002926027.1 937257 D 595496 CDS YP_002926028.1 238900232 7953935 937961..938548 1 NC_012759.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 938548 hyaD 7953935 hyaD Escherichia coli BW2952 hydrogenase 1 maturation protease YP_002926028.1 937961 D 595496 CDS YP_002926029.1 238900233 7955797 938545..938943 1 NC_012759.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 938943 hyaE 7955797 hyaE Escherichia coli BW2952 hydrogenase-1 operon protein HyaE YP_002926029.1 938545 D 595496 CDS YP_002926030.1 238900234 7955798 938940..939797 1 NC_012759.1 MG1655 equivalent: b0977; protein involved in nickel incorporation into hydrogenase-1 proteins 939797 hyaF 7955798 hyaF Escherichia coli BW2952 protein involved in nickel incorporation into hydrogenase-1 proteins YP_002926030.1 938940 D 595496 CDS YP_002926031.1 238900235 7955795 939931..941475 1 NC_012759.1 MG1655 equivalent: b0978; cytochrome bd-II oxidase, subunit I 941475 appC 7955795 appC Escherichia coli BW2952 cytochrome bd-II oxidase, subunit I YP_002926031.1 939931 D 595496 CDS YP_002926032.1 238900236 7953191 941487..942623 1 NC_012759.1 MG1655 equivalent: b0979; cytochrome bd-II oxidase, subunit II 942623 appB 7953191 appB Escherichia coli BW2952 cytochrome bd-II oxidase, subunit II YP_002926032.1 941487 D 595496 CDS YP_002926033.1 238900237 7953192 942636..942728 1 NC_012759.1 expressed during stationary phase; membrane protein 942728 yccB 7953192 yccB Escherichia coli BW2952 membrane protein YP_002926033.1 942636 D 595496 CDS YP_002926034.1 238900238 7953976 942808..944106 1 NC_012759.1 MG1655 equivalent: b0980; phosphoanhydride phosphorylase 944106 appA 7953976 appA Escherichia coli BW2952 phosphoanhydride phosphorylase YP_002926034.1 942808 D 595496 CDS YP_002926035.1 238900239 7954527 complement(944221..946401) 1 NC_012759.1 MG1655 equivalent: b0981; cryptic autophosphorylating protein tyrosine kinase Etk 946401 etk 7954527 etk Escherichia coli BW2952 cryptic autophosphorylating protein tyrosine kinase Etk YP_002926035.1 944221 R 595496 CDS YP_002926036.1 238900240 7953167 complement(946421..946867) 1 NC_012759.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase 946867 etp 7953167 etp Escherichia coli BW2952 phosphotyrosine-protein phosphatase YP_002926036.1 946421 R 595496 CDS YP_002926037.1 238900241 7954556 complement(946855..947994) 1 NC_012759.1 MG1655 equivalent: b0983; putative exopolysaccharide export protein 947994 gfcE 7954556 gfcE Escherichia coli BW2952 putative exopolysaccharide export protein YP_002926037.1 946855 R 595496 CDS YP_002926038.1 238900242 7954865 complement(948040..950136) 1 NC_012759.1 MG1655 equivalent: b0984; hypothetical protein 950136 gfcD 7954865 gfcD Escherichia coli BW2952 hypothetical protein YP_002926038.1 948040 R 595496 CDS YP_002926039.1 238900243 7952783 complement(950136..950882) 1 NC_012759.1 MG1655 equivalent: b0985; hypothetical protein 950882 gfcC 7952783 gfcC Escherichia coli BW2952 hypothetical protein YP_002926039.1 950136 R 595496 CDS YP_002926040.1 238900244 7952784 complement(950879..951523) 1 NC_012759.1 MG1655 equivalent: b0986; putative outer membrane lipoprotein 951523 gfcB 7952784 gfcB Escherichia coli BW2952 putative outer membrane lipoprotein YP_002926040.1 950879 R 595496 CDS YP_002926041.1 238900245 7955198 complement(951630..951935) 1 NC_012759.1 MG1655 equivalent: b0987; hypothetical protein 951935 gfcA 7955198 gfcA Escherichia coli BW2952 hypothetical protein YP_002926041.1 951630 R 595496 CDS YP_002926042.1 238900246 7955345 952024..952299 1 NC_012759.1 MG1655 equivalent: b4516; KpLE2 phage-like element; IS1 repressor protein InsA 952299 insA 7955345 insA Escherichia coli BW2952 KpLE2 phage-like element; IS1 repressor protein InsA YP_002926042.1 952024 D 595496 CDS YP_002926043.1 238900247 7954070 952218..952721 1 NC_012759.1 MG1655 equivalent: b0988; IS1 transposase InsAB' 952721 insB 7954070 insB Escherichia coli BW2952 IS1 transposase InsAB' YP_002926043.1 952218 D 595496 CDS YP_002926044.1 238900248 7954021 complement(953154..953366) 1 NC_012759.1 MG1655 equivalent: b0989; stress protein, member of the CspA-family 953366 cspH 7954021 cspH Escherichia coli BW2952 stress protein, member of the CspA-family YP_002926044.1 953154 R 595496 CDS YP_002926045.1 238900249 7956069 953652..953864 1 NC_012759.1 MG1655 equivalent: b0990; cold shock protein CspG 953864 cspG 7956069 cspG Escherichia coli BW2952 cold shock protein CspG YP_002926045.1 953652 D 595496 CDS YP_002926046.1 238900250 7953443 954038..954268 1 NC_012759.1 MG1655 equivalent: b0991; cold shock gene 954268 ymcE 7953443 ymcE Escherichia coli BW2952 cold shock gene YP_002926046.1 954038 D 595496 CDS YP_002926047.1 238900251 7952652 954258..954431 1 NC_012759.1 MG1655 equivalent: b4517; putative regulator of phosphatidylethanolamine synthesis 954431 gnsA 7952652 gnsA Escherichia coli BW2952 putative regulator of phosphatidylethanolamine synthesis YP_002926047.1 954258 D 595496 CDS YP_002926048.1 238900252 7955565 complement(954480..955553) 1 NC_012759.1 MG1655 equivalent: b0992; putative 4Fe-4S membrane protein 955553 yccM 7955565 yccM Escherichia coli BW2952 putative 4Fe-4S membrane protein YP_002926048.1 954480 R 595496 CDS YP_002926049.1 238900253 7954596 complement(955625..958369) 1 NC_012759.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 958369 torS 7954596 torS Escherichia coli BW2952 hybrid sensory histidine kinase TorS YP_002926049.1 955625 R 595496 CDS YP_002926050.1 238900254 7953930 958452..959480 1 NC_012759.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 959480 torT 7953930 torT Escherichia coli BW2952 TMAO reductase system periplasmic protein TorT YP_002926050.1 958452 D 595496 CDS YP_002926051.1 238900255 7954500 complement(959453..960145) 1 NC_012759.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 960145 torR 7954500 torR Escherichia coli BW2952 DNA-binding transcriptional regulator TorR YP_002926051.1 959453 R 595496 CDS YP_002926052.1 238900256 7953362 960275..961447 1 NC_012759.1 MG1655 equivalent: b0996; trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 961447 torC 7953362 torC Escherichia coli BW2952 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit YP_002926052.1 960275 D 595496 CDS YP_002926053.1 238900257 7956191 961447..963993 1 NC_012759.1 MG1655 equivalent: b0997; trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 963993 torA 7956191 torA Escherichia coli BW2952 trimethylamine N-oxide (TMAO) reductase I, catalytic subunit YP_002926053.1 961447 D 595496 CDS YP_002926054.1 238900258 7956190 963990..964589 1 NC_012759.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 964589 torD 7956190 torD Escherichia coli BW2952 chaperone protein TorD YP_002926054.1 963990 D 595496 CDS YP_002926055.1 238900259 7952629 complement(964741..965046) 1 NC_012759.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 965046 cbpM 7952629 cbpM Escherichia coli BW2952 chaperone-modulator protein CbpM YP_002926055.1 964741 R 595496 CDS YP_002926056.1 238900260 7954277 complement(965046..965966) 1 NC_012759.1 functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 965966 cbpA 7954277 cbpA Escherichia coli BW2952 curved DNA-binding protein CbpA YP_002926056.1 965046 R 595496 CDS YP_002926057.1 238900261 7953175 966227..967483 1 NC_012759.1 MG1655 equivalent: b1001; hypothetical protein 967483 yccE 7953175 yccE Escherichia coli BW2952 hypothetical protein YP_002926057.1 966227 D 595496 CDS YP_002926058.1 238900262 7955451 967776..969017 1 NC_012759.1 MG1655 equivalent: b1002; glucose-1-phosphatase/inositol phosphatase 969017 agp 7955451 agp Escherichia coli BW2952 glucose-1-phosphatase/inositol phosphatase YP_002926058.1 967776 D 595496 CDS YP_002926059.1 238900263 7953804 complement(969055..969282) 1 NC_012759.1 MG1655 equivalent: b1003; hypothetical protein 969282 yccJ 7953804 yccJ Escherichia coli BW2952 hypothetical protein YP_002926059.1 969055 R 595496 CDS YP_002926060.1 238900264 7955346 complement(969303..969899) 1 NC_012759.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 969899 wrbA 7955346 wrbA Escherichia coli BW2952 TrpR binding protein WrbA YP_002926060.1 969303 R 595496 CDS YP_002926061.1 238900265 7954350 970272..970445 1 NC_012759.1 MG1655 equivalent: b4518; hypothetical protein 970445 ymdF 7954350 ymdF Escherichia coli BW2952 hypothetical protein YP_002926061.1 970272 D 595496 CDS YP_002926062.1 238900266 7953073 complement(970702..972030) 1 NC_012759.1 MG1655 equivalent: b1006; putative transporter 972030 rutG 7953073 rutG Escherichia coli BW2952 putative transporter YP_002926062.1 970702 R 595496 CDS YP_002926063.1 238900267 7955654 complement(972051..972545) 1 NC_012759.1 MG1655 equivalent: b1007; putative oxidoreductase, flavin:NADH component 972545 rutF 7955654 rutF Escherichia coli BW2952 putative oxidoreductase, flavin:NADH component YP_002926063.1 972051 R 595496 CDS YP_002926064.1 238900268 7955253 complement(972556..973146) 1 NC_012759.1 MG1655 equivalent: b1008; hypothetical protein 973146 rutE 7955253 rutE Escherichia coli BW2952 hypothetical protein YP_002926064.1 972556 R 595496 CDS YP_002926065.1 238900269 7955222 complement(973156..973956) 1 NC_012759.1 MG1655 equivalent: b1009; putative hydrolase 973956 rutD 7955222 rutD Escherichia coli BW2952 putative hydrolase YP_002926065.1 973156 R 595496 CDS YP_002926066.1 238900270 7954953 complement(973964..974350) 1 NC_012759.1 MG1655 equivalent: b1010; hypothetical protein 974350 rutC 7954953 rutC Escherichia coli BW2952 hypothetical protein YP_002926066.1 973964 R 595496 CDS YP_002926067.1 238900271 7952785 complement(974362..975054) 1 NC_012759.1 MG1655 equivalent: b1011; putative enzyme 975054 rutB 7952785 rutB Escherichia coli BW2952 putative enzyme YP_002926067.1 974362 R 595496 CDS YP_002926068.1 238900272 7954838 complement(975054..976202) 1 NC_012759.1 MG1655 equivalent: b1012; putative monooxygenase 976202 rutA 7954838 rutA Escherichia coli BW2952 putative monooxygenase YP_002926068.1 975054 R 595496 CDS YP_002926069.1 238900273 7955165 976433..977071 1 NC_012759.1 MG1655 equivalent: b1013; putative DNA-binding transcriptional regulator 977071 rutR 7955165 rutR Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926069.1 976433 D 595496 CDS YP_002926070.1 238900274 7954794 complement(977111..981073) 1 NC_012759.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 981073 putA 7954794 putA Escherichia coli BW2952 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002926070.1 977111 R 595496 CDS YP_002926071.1 238900275 7953676 981496..983004 1 NC_012759.1 MG1655 equivalent: b1015; proline:sodium symporter 983004 putP 7953676 putP Escherichia coli BW2952 proline:sodium symporter YP_002926071.1 981496 D 595496 CDS YP_002926072.1 238900276 7955770 984434..985561 1 NC_012759.1 MG1655 equivalent: b1018; hypothetical protein 985561 efeO 7955770 efeO Escherichia coli BW2952 hypothetical protein YP_002926072.1 984434 D 595496 CDS YP_002926073.1 238900277 7952948 985567..986838 1 NC_012759.1 MG1655 equivalent: b1019; hypothetical protein 986838 efeB 7952948 efeB Escherichia coli BW2952 hypothetical protein YP_002926073.1 985567 D 595496 CDS YP_002926074.1 238900278 7952949 987183..988247 1 NC_012759.1 MG1655 equivalent: b1020; hypothetical protein 988247 phoH 7952949 phoH Escherichia coli BW2952 hypothetical protein YP_002926074.1 987183 D 595496 CDS YP_002926075.1 238900279 7953089 complement(988297..988710) 1 NC_012759.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; putative PGA biosynthesis protein 988710 pgaD 7953089 pgaD Escherichia coli BW2952 putative PGA biosynthesis protein YP_002926075.1 988297 R 595496 CDS YP_002926076.1 238900280 7954989 complement(988712..990037) 1 NC_012759.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 990037 pgaC 7954989 pgaC Escherichia coli BW2952 N-glycosyltransferase YP_002926076.1 988712 R 595496 CDS YP_002926077.1 238900281 7954932 complement(990030..992048) 1 NC_012759.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 992048 pgaB 7954932 pgaB Escherichia coli BW2952 outer membrane N-deacetylase YP_002926077.1 990030 R 595496 CDS YP_002926078.1 238900282 7954850 complement(992057..994480) 1 NC_012759.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 994480 pgaA 7954850 pgaA Escherichia coli BW2952 outer membrane protein PgaA YP_002926078.1 992057 R 595496 CDS YP_002926079.1 238900283 7955211 994837..995340 1 NC_012759.1 Insertion element IS1 1/5/6 protein insB 995340 7955211 BWG_0877 Escherichia coli BW2952 Insertion element IS1 1/5/6 protein insB YP_002926079.1 994837 D 595496 CDS YP_002926080.1 238900284 7954003 995843..997201 1 NC_012759.1 MG1655 equivalent: b1025; putative diguanylate cyclase 997201 ycdT 7954003 ycdT Escherichia coli BW2952 putative diguanylate cyclase YP_002926080.1 995843 D 595496 CDS YP_002926081.1 238900285 7954728 complement(997242..998108) 1 NC_012759.1 MG1655 equivalent: b1026; IS3 element protein InsF 998108 insF 7954728 insF Escherichia coli BW2952 IS3 element protein InsF YP_002926081.1 997242 R 595496 CDS YP_002926082.1 238900286 7954033 complement(998105..998413) 1 NC_012759.1 MG1655 equivalent: b1027; IS3 element protein InsE 998413 insE 7954033 insE Escherichia coli BW2952 IS3 element protein InsE YP_002926082.1 998105 R 595496 CDS YP_002926083.1 238900287 7954029 998810..999796 1 NC_012759.1 MG1655 equivalent: b1029; putative inner membrane protein 999796 ycdU 7954029 ycdU Escherichia coli BW2952 putative inner membrane protein YP_002926083.1 998810 D 595496 CDS YP_002926084.1 238900288 7952050 1001034..1001972 1 NC_012759.1 MG1655 equivalent: b1033; 2-ketoacid reductase 1001972 ghrA 7952050 ghrA Escherichia coli BW2952 2-ketoacid reductase YP_002926084.1 1001034 D 595496 CDS YP_002926085.1 238900289 7952262 1002027..1002764 1 NC_012759.1 MG1655 equivalent: b1034; putative hydrolase 1002764 ycdX 7952262 ycdX Escherichia coli BW2952 putative hydrolase YP_002926085.1 1002027 D 595496 CDS YP_002926086.1 238900290 7955754 1002788..1003342 1 NC_012759.1 MG1655 equivalent: b1035; hypothetical protein 1003342 ycdY 7955754 ycdY Escherichia coli BW2952 hypothetical protein YP_002926086.1 1002788 D 595496 CDS YP_002926087.1 238900291 7952950 1003444..1003935 1 NC_012759.1 MG1655 equivalent: b1036; putative inner membrane protein 1003935 ycdZ 7952950 ycdZ Escherichia coli BW2952 putative inner membrane protein YP_002926087.1 1003444 D 595496 CDS YP_002926088.1 238900292 7955033 complement(1003999..1004832) 1 NC_012759.1 MG1655 equivalent: b1037; outer membrane lipoprotein 1004832 csgG 7955033 csgG Escherichia coli BW2952 outer membrane lipoprotein YP_002926088.1 1003999 R 595496 CDS YP_002926089.1 238900293 7954437 complement(1004859..1005275) 1 NC_012759.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1005275 csgF 7954437 csgF Escherichia coli BW2952 curli assembly protein CsgF YP_002926089.1 1004859 R 595496 CDS YP_002926090.1 238900294 7955645 complement(1005300..1005689) 1 NC_012759.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1005689 csgE 7955645 csgE Escherichia coli BW2952 curli assembly protein CsgE YP_002926090.1 1005300 R 595496 CDS YP_002926091.1 238900295 7954581 complement(1005694..1006344) 1 NC_012759.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1006344 csgD 7954581 csgD Escherichia coli BW2952 DNA-binding transcriptional regulator CsgD YP_002926091.1 1005694 R 595496 CDS YP_002926092.1 238900296 7953386 1007099..1007554 1 NC_012759.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1007554 csgB 7953386 csgB Escherichia coli BW2952 curlin minor subunit YP_002926092.1 1007099 D 595496 CDS YP_002926093.1 238900297 7953174 1007595..1008050 1 NC_012759.1 MG1655 equivalent: b1042; cryptic curlin major subunit 1008050 csgA 7953174 csgA Escherichia coli BW2952 cryptic curlin major subunit YP_002926093.1 1007595 D 595496 CDS YP_002926094.1 238900298 7953170 1008109..1008441 1 NC_012759.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 1008441 csgC 7953170 csgC Escherichia coli BW2952 putative autoagglutination protein YP_002926094.1 1008109 D 595496 CDS YP_002926095.1 238900299 7954704 1008562..1008873 1 NC_012759.1 MG1655 equivalent: b1044; hypothetical protein 1008873 ymdA 7954704 ymdA Escherichia coli BW2952 hypothetical protein YP_002926095.1 1008562 D 595496 CDS YP_002926096.1 238900300 7955452 1008968..1009501 1 NC_012759.1 MG1655 equivalent: b1045; hypothetical protein 1009501 ymdB 7955452 ymdB Escherichia coli BW2952 hypothetical protein YP_002926096.1 1008968 D 595496 CDS YP_002926097.1 238900301 7952951 1009503..1010924 1 NC_012759.1 MG1655 equivalent: b1046; putative hydrolase 1010924 ymdC 7952951 ymdC Escherichia coli BW2952 putative hydrolase YP_002926097.1 1009503 D 595496 CDS YP_002926098.1 238900302 7954963 complement(1010932..1012089) 1 NC_012759.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1012089 mdoC 7954963 mdoC Escherichia coli BW2952 glucans biosynthesis protein YP_002926098.1 1010932 R 595496 CDS YP_002926099.1 238900303 7954232 1012483..1014018 1 NC_012759.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1014018 mdoG 7954232 mdoG Escherichia coli BW2952 glucan biosynthesis protein G YP_002926099.1 1012483 D 595496 CDS YP_002926100.1 238900304 7953790 1014011..1016554 1 NC_012759.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1016554 mdoH 7953790 mdoH Escherichia coli BW2952 glucosyltransferase MdoH YP_002926100.1 1014011 D 595496 CDS YP_002926101.1 238900305 7953792 1016727..1016954 1 NC_012759.1 MG1655 equivalent: b1050; hypothetical protein 1016954 yceK 7953792 yceK Escherichia coli BW2952 hypothetical protein YP_002926101.1 1016727 D 595496 CDS YP_002926102.1 238900306 7955113 complement(1016955..1017329) 1 NC_012759.1 MG1655 equivalent: b1051; hypothetical protein 1017329 msyB 7955113 msyB Escherichia coli BW2952 hypothetical protein YP_002926102.1 1016955 R 595496 CDS YP_002926103.1 238900307 7955347 complement(1017412..1018638) 1 NC_012759.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1018638 mdtG 7955347 mdtG Escherichia coli BW2952 drug efflux system protein MdtG YP_002926103.1 1017412 R 595496 CDS YP_002926104.1 238900308 7954827 complement(1018810..1019730) 1 NC_012759.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1019730 lpxL 7954827 lpxL Escherichia coli BW2952 lipid A biosynthesis lauroyl acyltransferase YP_002926104.1 1018810 R 595496 CDS YP_002926105.1 238900309 7954122 1019955..1021007 1 NC_012759.1 MG1655 equivalent: b1055; hypothetical protein 1021007 yceA 7954122 yceA Escherichia coli BW2952 hypothetical protein YP_002926105.1 1019955 D 595496 CDS YP_002926106.1 238900310 7952952 complement(1021049..1021624) 1 NC_012759.1 MG1655 equivalent: b1056; hypothetical protein 1021624 yceI 7952952 yceI Escherichia coli BW2952 hypothetical protein YP_002926106.1 1021049 R 595496 CDS YP_002926107.1 238900311 7955348 complement(1021628..1022194) 1 NC_012759.1 MG1655 equivalent: b1057; putative cytochrome b561 1022194 yceJ 7955348 yceJ Escherichia coli BW2952 putative cytochrome b561 YP_002926107.1 1021628 R 595496 CDS YP_002926108.1 238900312 7954708 complement(1022455..1022595) 1 NC_012759.1 MG1655 equivalent: b1058; hypothetical protein 1022595 yceO 7954708 yceO Escherichia coli BW2952 hypothetical protein YP_002926108.1 1022455 R 595496 CDS YP_002926109.1 238900313 7955349 complement(1022616..1023734) 1 NC_012759.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1023734 solA 7955349 solA Escherichia coli BW2952 N-methyltryptophan oxidase YP_002926109.1 1022616 R 595496 CDS YP_002926110.1 238900314 7954406 complement(1023849..1024103) 1 NC_012759.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1024103 bssS 7954406 bssS Escherichia coli BW2952 biofilm formation regulatory protein BssS YP_002926110.1 1023849 R 595496 CDS YP_002926111.1 238900315 7955350 complement(1024390..1024635) 1 NC_012759.1 MG1655 equivalent: b1061; DNA damage-inducible protein I 1024635 dinI 7955350 dinI Escherichia coli BW2952 DNA damage-inducible protein I YP_002926111.1 1024390 R 595496 CDS YP_002926112.1 238900316 7953303 complement(1024709..1025755) 1 NC_012759.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1025755 pyrC 7953303 pyrC Escherichia coli BW2952 dihydroorotase YP_002926112.1 1024709 R 595496 CDS YP_002926113.1 238900317 7953254 complement(1025861..1026421) 1 NC_012759.1 MG1655 equivalent: b1063; hypothetical protein 1026421 yceB 7953254 yceB Escherichia coli BW2952 hypothetical protein YP_002926113.1 1025861 R 595496 CDS YP_002926114.1 238900318 7955106 complement(1026555..1027202) 1 NC_012759.1 cofactor involved in the reduction of disulfides; glutaredoxin 1027202 grxB 7955106 grxB Escherichia coli BW2952 glutaredoxin YP_002926114.1 1026555 R 595496 CDS YP_002926115.1 238900319 7953836 complement(1027266..1028474) 1 NC_012759.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1028474 mdtH 7953836 mdtH Escherichia coli BW2952 multidrug resistance protein MdtH YP_002926115.1 1027266 R 595496 CDS YP_002926116.1 238900320 7954828 1028710..1029294 1 NC_012759.1 MG1655 equivalent: b1066; ribosomal-protein-S5-alanine N-acetyltransferase 1029294 rimJ 7954828 rimJ Escherichia coli BW2952 ribosomal-protein-S5-alanine N-acetyltransferase YP_002926116.1 1028710 D 595496 CDS YP_002926117.1 238900321 7955976 1029305..1029952 1 NC_012759.1 MG1655 equivalent: b1067; hypothetical protein 1029952 yceH 7955976 yceH Escherichia coli BW2952 hypothetical protein YP_002926117.1 1029305 D 595496 CDS YP_002926118.1 238900322 7952953 1029954..1030877 1 NC_012759.1 MG1655 equivalent: b1068; putative oxidoreductase with NAD(P)-binding Rossmann-fold domain 1030877 yceM 7952953 yceM Escherichia coli BW2952 putative oxidoreductase with NAD(P)-binding Rossmann-fold domain YP_002926118.1 1029954 D 595496 CDS YP_002926119.1 238900323 7955250 1030987..1032522 1 NC_012759.1 MG1655 equivalent: b1069; putative inner membrane protein 1032522 yceN 7955250 yceN Escherichia coli BW2952 putative inner membrane protein YP_002926119.1 1030987 D 595496 CDS YP_002926120.1 238900324 7955034 complement(1032562..1032978) 1 NC_012759.1 MG1655 equivalent: b1070; export chaperone for FlgK and FlgL 1032978 flgN 7955034 flgN Escherichia coli BW2952 export chaperone for FlgK and FlgL YP_002926120.1 1032562 R 595496 CDS YP_002926121.1 238900325 7953550 complement(1032983..1033276) 1 NC_012759.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1033276 flgM 7953550 flgM Escherichia coli BW2952 anti-sigma-28 factor FlgM YP_002926121.1 1032983 R 595496 CDS YP_002926122.1 238900326 7952484 complement(1033352..1034011) 1 NC_012759.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1034011 flgA 7952484 flgA Escherichia coli BW2952 flagellar basal body P-ring biosynthesis protein FlgA YP_002926122.1 1033352 R 595496 CDS YP_002926123.1 238900327 7952518 1034166..1034582 1 NC_012759.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1034582 flgB 7952518 flgB Escherichia coli BW2952 flagellar basal body rod protein FlgB YP_002926123.1 1034166 D 595496 CDS YP_002926124.1 238900328 7953590 1034586..1034990 1 NC_012759.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1034990 flgC 7953590 flgC Escherichia coli BW2952 flagellar basal body rod protein FlgC YP_002926124.1 1034586 D 595496 CDS YP_002926125.1 238900329 7953591 1035002..1035697 1 NC_012759.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1035697 flgD 7953591 flgD Escherichia coli BW2952 flagellar basal body rod modification protein YP_002926125.1 1035002 D 595496 CDS YP_002926126.1 238900330 7953596 1035722..1036930 1 NC_012759.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1036930 flgE 7953596 flgE Escherichia coli BW2952 flagellar hook protein FlgE YP_002926126.1 1035722 D 595496 CDS YP_002926127.1 238900331 7953597 1036950..1037705 1 NC_012759.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1037705 flgF 7953597 flgF Escherichia coli BW2952 flagellar basal body rod protein FlgF YP_002926127.1 1036950 D 595496 CDS YP_002926128.1 238900332 7953592 1037877..1038659 1 NC_012759.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1038659 flgG 7953592 flgG Escherichia coli BW2952 flagellar basal body rod protein FlgG YP_002926128.1 1037877 D 595496 CDS YP_002926129.1 238900333 7953589 1038712..1039410 1 NC_012759.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1039410 flgH 7953589 flgH Escherichia coli BW2952 flagellar basal body L-ring protein YP_002926129.1 1038712 D 595496 CDS YP_002926130.1 238900334 7953605 1039422..1040519 1 NC_012759.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1040519 flgI 7953605 flgI Escherichia coli BW2952 flagellar basal body P-ring protein YP_002926130.1 1039422 D 595496 CDS YP_002926131.1 238900335 7954903 1040519..1041460 1 NC_012759.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1041460 flgJ 7954903 flgJ Escherichia coli BW2952 flagellar rod assembly protein/muramidase FlgJ YP_002926131.1 1040519 D 595496 CDS YP_002926132.1 238900336 7954319 1041526..1043169 1 NC_012759.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1043169 flgK 7954319 flgK Escherichia coli BW2952 flagellar hook-associated protein FlgK YP_002926132.1 1041526 D 595496 CDS YP_002926133.1 238900337 7953599 1043181..1044134 1 NC_012759.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1044134 flgL 7953599 flgL Escherichia coli BW2952 flagellar hook-associated protein FlgL YP_002926133.1 1043181 D 595496 CDS YP_002926134.1 238900338 7953598 complement(1044330..1047515) 1 NC_012759.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1047515 rne 7953598 rne Escherichia coli BW2952 ribonuclease E YP_002926134.1 1044330 R 595496 CDS YP_002926135.1 238900339 7953739 1047650..1047970 1 NC_012759.1 MG1655 equivalent: b1085; hypothetical protein 1047970 yceQ 7953739 yceQ Escherichia coli BW2952 hypothetical protein YP_002926135.1 1047650 D 595496 CDS YP_002926136.1 238900340 7955453 1048088..1049047 1 NC_012759.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1049047 rluC 7955453 rluC Escherichia coli BW2952 23S rRNA pseudouridylate synthase C YP_002926136.1 1048088 D 595496 CDS YP_002926137.1 238900341 7952249 complement(1049159..1049743) 1 NC_012759.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1049743 yceF 7952249 yceF Escherichia coli BW2952 Maf-like protein YP_002926137.1 1049159 R 595496 CDS YP_002926138.1 238900342 7952172 1049942..1050463 1 NC_012759.1 MG1655 equivalent: b1088; hypothetical protein 1050463 yceD 7952172 yceD Escherichia coli BW2952 hypothetical protein YP_002926138.1 1049942 D 595496 CDS YP_002926139.1 238900343 7952954 1050515..1050688 1 NC_012759.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1050688 rpmF 7952954 rpmF Escherichia coli BW2952 50S ribosomal protein L32 YP_002926139.1 1050515 D 595496 CDS YP_002926140.1 238900344 7952360 1050769..1051839 1 NC_012759.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1051839 plsX 7952360 plsX Escherichia coli BW2952 putative glycerol-3-phosphate acyltransferase PlsX YP_002926140.1 1050769 D 595496 CDS YP_002926141.1 238900345 7953561 1051907..1052860 1 NC_012759.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1052860 fabH 7953561 fabH Escherichia coli BW2952 3-oxoacyl-ACP synthase YP_002926141.1 1051907 D 595496 CDS YP_002926142.1 238900346 7952320 1052876..1053805 1 NC_012759.1 MG1655 equivalent: b1092; malonyl CoA-ACP transacylase 1053805 fabD 7952320 fabD Escherichia coli BW2952 malonyl CoA-ACP transacylase YP_002926142.1 1052876 D 595496 CDS YP_002926143.1 238900347 7954202 1053818..1054552 1 NC_012759.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1054552 fabG 7954202 fabG Escherichia coli BW2952 3-ketoacyl-ACP reductase YP_002926143.1 1053818 D 595496 CDS YP_002926144.1 238900348 7952317 1054763..1054999 1 NC_012759.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1054999 acpP 7952317 acpP Escherichia coli BW2952 acyl carrier protein YP_002926144.1 1054763 D 595496 CDS YP_002926145.1 238900349 7952413 1055087..1056328 1 NC_012759.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1056328 fabF 7952413 fabF Escherichia coli BW2952 3-oxoacyl-(acyl carrier protein) synthase II YP_002926145.1 1055087 D 595496 CDS YP_002926146.1 238900350 7952319 1056448..1057257 1 NC_012759.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1057257 pabC 7952319 pabC Escherichia coli BW2952 4-amino-4-deoxychorismate lyase YP_002926146.1 1056448 D 595496 CDS YP_002926147.1 238900351 7952328 1057260..1058282 1 NC_012759.1 MG1655 equivalent: b1097; hypothetical protein 1058282 yceG 7952328 yceG Escherichia coli BW2952 hypothetical protein YP_002926147.1 1057260 D 595496 CDS YP_002926148.1 238900352 7954645 1058272..1058913 1 NC_012759.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1058913 tmk 7954645 tmk Escherichia coli BW2952 thymidylate kinase YP_002926148.1 1058272 D 595496 CDS YP_002926149.1 238900353 7956150 1058910..1059914 1 NC_012759.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1059914 holB 7956150 holB Escherichia coli BW2952 DNA polymerase III subunit delta' YP_002926149.1 1058910 D 595496 CDS YP_002926150.1 238900354 7953322 1059925..1060722 1 NC_012759.1 MG1655 equivalent: b1100; putative metallodependent hydrolase 1060722 ycfH 7953322 ycfH Escherichia coli BW2952 putative metallodependent hydrolase YP_002926150.1 1059925 D 595496 CDS YP_002926151.1 238900355 7955148 1061017..1062450 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1062450 ptsG 7955148 ptsG Escherichia coli BW2952 PTS system glucose-specific transporter subunit IIBC YP_002926151.1 1061017 D 595496 CDS YP_002926152.1 238900356 7953682 complement(1062510..1064699) 1 NC_012759.1 MG1655 equivalent: b1102; ferric-rhodotorulic acid outer membrane transporter 1064699 fhuE 7953682 fhuE Escherichia coli BW2952 ferric-rhodotorulic acid outer membrane transporter YP_002926152.1 1062510 R 595496 CDS YP_002926153.1 238900357 7953571 1065033..1065392 1 NC_012759.1 MG1655 equivalent: b1103; purine nucleoside phosphoramidase 1065392 hinT 7953571 hinT Escherichia coli BW2952 purine nucleoside phosphoramidase YP_002926153.1 1065033 D 595496 CDS YP_002926154.1 238900358 7955822 1065395..1065772 1 NC_012759.1 MG1655 equivalent: b1104; hypothetical protein 1065772 ycfL 7955822 ycfL Escherichia coli BW2952 hypothetical protein YP_002926154.1 1065395 D 595496 CDS YP_002926155.1 238900359 7955454 1065786..1066427 1 NC_012759.1 MG1655 equivalent: b1105; putative outer membrane lipoprotein 1066427 ycfM 7955454 ycfM Escherichia coli BW2952 putative outer membrane lipoprotein YP_002926155.1 1065786 D 595496 CDS YP_002926156.1 238900360 7955201 1066408..1067232 1 NC_012759.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1067232 thiK 7955201 thiK Escherichia coli BW2952 thiamine kinase YP_002926156.1 1066408 D 595496 CDS YP_002926157.1 238900361 7956126 1067243..1068268 1 NC_012759.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1068268 nagZ 7956126 nagZ Escherichia coli BW2952 beta-hexosaminidase YP_002926157.1 1067243 D 595496 CDS YP_002926158.1 238900362 7952545 1068291..1068833 1 NC_012759.1 MG1655 equivalent: b1108; hypothetical protein 1068833 ycfP 7952545 ycfP Escherichia coli BW2952 hypothetical protein YP_002926158.1 1068291 D 595496 CDS YP_002926159.1 238900363 7952955 1069233..1070537 1 NC_012759.1 MG1655 equivalent: b1109; respiratory NADH dehydrogenase 2/cupric reductase 1070537 ndh 7952955 ndh Escherichia coli BW2952 respiratory NADH dehydrogenase 2/cupric reductase YP_002926159.1 1069233 D 595496 CDS YP_002926160.1 238900364 7955943 1070747..1071286 1 NC_012759.1 MG1655 equivalent: b1110; hypothetical protein 1071286 ycfJ 7955943 ycfJ Escherichia coli BW2952 hypothetical protein YP_002926160.1 1070747 D 595496 CDS YP_002926161.1 238900365 7955455 complement(1071348..1071980) 1 NC_012759.1 MG1655 equivalent: b1111; putative DNA-binding transcriptional regulator 1071980 ycfQ 7955455 ycfQ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926161.1 1071348 R 595496 CDS YP_002926162.1 238900366 7954752 1072221..1072478 1 NC_012759.1 MG1655 equivalent: b1112; hypothetical protein 1072478 bhsA 7954752 bhsA Escherichia coli BW2952 hypothetical protein YP_002926162.1 1072221 D 595496 CDS YP_002926163.1 238900367 7955456 complement(1072560..1073522) 1 NC_012759.1 MG1655 equivalent: b1113; hypothetical protein 1073522 ycfS 7955456 ycfS Escherichia coli BW2952 hypothetical protein YP_002926163.1 1072560 R 595496 CDS YP_002926164.1 238900368 7952786 complement(1073666..1077112) 1 NC_012759.1 MG1655 equivalent: b1114; transcription-repair coupling factor 1077112 mfd 7952786 mfd Escherichia coli BW2952 transcription-repair coupling factor YP_002926164.1 1073666 R 595496 CDS YP_002926165.1 238900369 7956173 complement(1077240..1078313) 1 NC_012759.1 MG1655 equivalent: b1115; putative inner membrane protein 1078313 ycfT 7956173 ycfT Escherichia coli BW2952 putative inner membrane protein YP_002926165.1 1077240 R 595496 CDS YP_002926166.1 238900370 7954990 1078575..1079774 1 NC_012759.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1079774 lolC 7954990 lolC Escherichia coli BW2952 outer membrane-specific lipoprotein transporter subunit LolC YP_002926166.1 1078575 D 595496 CDS YP_002926167.1 238900371 7954452 1079767..1080468 1 NC_012759.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1080468 lolD 7954452 lolD Escherichia coli BW2952 lipoprotein transporter ATP-binding subunit YP_002926167.1 1079767 D 595496 CDS YP_002926168.1 238900372 7954453 1080468..1081712 1 NC_012759.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1081712 lolE 7954453 lolE Escherichia coli BW2952 outer membrane-specific lipoprotein transporter subunit LolE YP_002926168.1 1080468 D 595496 CDS YP_002926169.1 238900373 7954454 1081741..1082652 1 NC_012759.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1082652 nagK 7954454 nagK Escherichia coli BW2952 N-acetyl-D-glucosamine kinase YP_002926169.1 1081741 D 595496 CDS YP_002926170.1 238900374 7954335 1082668..1083507 1 NC_012759.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1083507 cobB 7954335 cobB Escherichia coli BW2952 NAD-dependent deacetylase YP_002926170.1 1082668 D 595496 CDS YP_002926171.1 238900375 7953230 complement(1083627..1084415) 1 NC_012759.1 MG1655 equivalent: b1121; putative inner membrane protein 1084415 ycfZ 7953230 ycfZ Escherichia coli BW2952 putative inner membrane protein YP_002926171.1 1083627 R 595496 CDS YP_002926172.1 238900376 7954991 complement(1084412..1084873) 1 NC_012759.1 MG1655 equivalent: b1122; putative inner membrane protein 1084873 ymfA 7954991 ymfA Escherichia coli BW2952 putative inner membrane protein YP_002926172.1 1084412 R 595496 CDS YP_002926173.1 238900377 7954992 complement(1084931..1085977) 1 NC_012759.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1085977 potD 7954992 potD Escherichia coli BW2952 spermidine/putrescine ABC transporter substrate-binding protein YP_002926173.1 1084931 R 595496 CDS YP_002926174.1 238900378 7954563 complement(1085974..1086768) 1 NC_012759.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1086768 potC 7954563 potC Escherichia coli BW2952 spermidine/putrescine ABC transporter membrane protein YP_002926174.1 1085974 R 595496 CDS YP_002926175.1 238900379 7954564 complement(1086765..1087592) 1 NC_012759.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1087592 potB 7954564 potB Escherichia coli BW2952 spermidine/putrescine ABC transporter membrane protein YP_002926175.1 1086765 R 595496 CDS YP_002926176.1 238900380 7954565 complement(1087606..1088742) 1 NC_012759.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1088742 potA 7954565 potA Escherichia coli BW2952 putrescine/spermidine ABC transporter ATPase YP_002926176.1 1087606 R 595496 CDS YP_002926177.1 238900381 7954566 1088992..1090218 1 NC_012759.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1090218 pepT 7954566 pepT Escherichia coli BW2952 peptidase T YP_002926177.1 1088992 D 595496 CDS YP_002926178.1 238900382 7954473 complement(1090267..1091388) 1 NC_012759.1 MG1655 equivalent: b1128; hypothetical protein 1091388 ycfD 7954473 ycfD Escherichia coli BW2952 hypothetical protein YP_002926178.1 1090267 R 595496 CDS YP_002926179.1 238900383 7952787 complement(1091464..1092924) 1 NC_012759.1 MG1655 equivalent: b1129; sensor protein PhoQ 1092924 phoQ 7952787 phoQ Escherichia coli BW2952 sensor protein PhoQ YP_002926179.1 1091464 R 595496 CDS YP_002926180.1 238900384 7956010 complement(1092924..1093595) 1 NC_012759.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1093595 phoP 7956010 phoP Escherichia coli BW2952 DNA-binding transcriptional regulator PhoP YP_002926180.1 1092924 R 595496 CDS YP_002926181.1 238900385 7953357 complement(1093764..1095134) 1 NC_012759.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1095134 purB 7953357 purB Escherichia coli BW2952 adenylosuccinate lyase YP_002926181.1 1093764 R 595496 CDS YP_002926182.1 238900386 7952424 complement(1095138..1095779) 1 NC_012759.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1095779 hflD 7952424 hflD Escherichia coli BW2952 hypothetical protein YP_002926182.1 1095138 R 595496 CDS YP_002926183.1 238900387 7955129 complement(1095815..1096921) 1 NC_012759.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1096921 mnmA 7955129 mnmA Escherichia coli BW2952 tRNA-specific 2-thiouridylase MnmA YP_002926183.1 1095815 R 595496 CDS YP_002926184.1 238900388 7956195 complement(1096975..1097436) 1 NC_012759.1 MG1655 equivalent: b1134; bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase 1097436 nudJ 7956195 nudJ Escherichia coli BW2952 bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase YP_002926184.1 1096975 R 595496 CDS YP_002926185.1 238900389 7952574 complement(1097446..1098099) 1 NC_012759.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1098099 rluE 7952574 rluE Escherichia coli BW2952 23S rRNA pseudouridine synthase E YP_002926185.1 1097446 R 595496 CDS YP_002926186.1 238900390 7952246 1098271..1099521 1 NC_012759.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1099521 icd 7952246 icd Escherichia coli BW2952 isocitrate dehydrogenase YP_002926186.1 1098271 D 595496 CDS YP_002926187.1 238900391 7953511 complement(1099624..1099947) 1 NC_012759.1 MG1655 equivalent: b1160; hypothetical protein 1099947 elbA 7953511 elbA Escherichia coli BW2952 hypothetical protein YP_002926187.1 1099624 R 595496 CDS YP_002926188.1 238900392 7955352 complement(1100647..1101051) 1 NC_012759.1 MG1655 equivalent: b1161; hypothetical protein 1101051 ycgX 7955352 ycgX Escherichia coli BW2952 hypothetical protein YP_002926188.1 1100647 R 595496 CDS YP_002926189.1 238900393 7955353 complement(1101272..1102003) 1 NC_012759.1 MG1655 equivalent: b1162; putative DNA-binding transcriptional regulator 1102003 ycgE 7955353 ycgE Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926189.1 1101272 R 595496 CDS YP_002926190.1 238900394 7954753 complement(1102208..1103419) 1 NC_012759.1 MG1655 equivalent: b1163; putative FAD-binding phosphodiesterase 1103419 ycgF 7954753 ycgF Escherichia coli BW2952 putative FAD-binding phosphodiesterase YP_002926190.1 1102208 R 595496 CDS YP_002926191.1 238900395 7954867 1103733..1103969 1 NC_012759.1 MG1655 equivalent: b1164; hypothetical protein 1103969 ycgZ 7954867 ycgZ Escherichia coli BW2952 hypothetical protein YP_002926191.1 1103733 D 595496 CDS YP_002926192.1 238900396 7955457 1104012..1104284 1 NC_012759.1 MG1655 equivalent: b1165; hypothetical protein 1104284 ymgA 7955457 ymgA Escherichia coli BW2952 hypothetical protein YP_002926192.1 1104012 D 595496 CDS YP_002926193.1 238900397 7955458 1104313..1104579 1 NC_012759.1 MG1655 equivalent: b1166; hypothetical protein 1104579 ariR 7955458 ariR Escherichia coli BW2952 hypothetical protein YP_002926193.1 1104313 D 595496 CDS YP_002926194.1 238900398 7955459 1104692..1104940 1 NC_012759.1 MG1655 equivalent: b1167; hypothetical protein 1104940 ymgC 7955459 ymgC Escherichia coli BW2952 hypothetical protein YP_002926194.1 1104692 D 595496 CDS YP_002926195.1 238900399 7955460 1105272..1106795 1 NC_012759.1 MG1655 equivalent: b1168; hypothetical protein 1106795 ycgG 7955460 ycgG Escherichia coli BW2952 hypothetical protein YP_002926195.1 1105272 D 595496 CDS YP_002926196.1 238900400 7952705 1106927..1107145 1 NC_012759.1 MG1655 equivalent: b4520; hypothetical protein 1107145 ymgF 7952705 ymgF Escherichia coli BW2952 hypothetical protein YP_002926196.1 1106927 D 595496 CDS YP_002926197.1 238900401 7955527 complement(1110249..1110578) 1 NC_012759.1 MG1655 equivalent: b1171; hypothetical protein 1110578 ymgD 7955527 ymgD Escherichia coli BW2952 hypothetical protein YP_002926197.1 1110249 R 595496 CDS YP_002926198.1 238900402 7955354 complement(1110588..1110872) 1 NC_012759.1 MG1655 equivalent: b1172; hypothetical protein 1110872 ymgG 7955354 ymgG Escherichia coli BW2952 hypothetical protein YP_002926198.1 1110588 R 595496 CDS YP_002926199.1 238900403 7955355 complement(1110934..1111107) 1 NC_012759.1 MG1655 equivalent: b4593; hypothetical protein 1111107 ymgI 7955355 ymgI Escherichia coli BW2952 hypothetical protein YP_002926199.1 1110934 R 595496 CDS YP_002926200.1 238900404 7953964 1111208..1111393 1 NC_012759.1 MG1655 equivalent: b4594; hypothetical protein 1111393 ymgJ 7953964 ymgJ Escherichia coli BW2952 hypothetical protein YP_002926200.1 1111208 D 595496 CDS YP_002926201.1 238900405 7953977 complement(1112223..1112489) 1 NC_012759.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1112489 minE 7953977 minE Escherichia coli BW2952 cell division topological specificity factor MinE YP_002926201.1 1112223 R 595496 CDS YP_002926202.1 238900406 7952618 complement(1112493..1113305) 1 NC_012759.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1113305 minD 7952618 minD Escherichia coli BW2952 cell division inhibitor MinD YP_002926202.1 1112493 R 595496 CDS YP_002926203.1 238900407 7954224 complement(1113329..1114024) 1 NC_012759.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1114024 minC 7954224 minC Escherichia coli BW2952 septum formation inhibitor YP_002926203.1 1113329 R 595496 CDS YP_002926204.1 238900408 7952614 1114544..1114912 1 NC_012759.1 MG1655 equivalent: b1177; hypothetical protein 1114912 ycgJ 7952614 ycgJ Escherichia coli BW2952 hypothetical protein YP_002926204.1 1114544 D 595496 CDS YP_002926205.1 238900409 7955461 complement(1115015..1115416) 1 NC_012759.1 MG1655 equivalent: b1178; hypothetical protein 1115416 ycgK 7955461 ycgK Escherichia coli BW2952 hypothetical protein YP_002926205.1 1115015 R 595496 CDS YP_002926206.1 238900410 7955356 1115625..1115951 1 NC_012759.1 MG1655 equivalent: b1179; hypothetical protein 1115951 ycgL 7955356 ycgL Escherichia coli BW2952 hypothetical protein YP_002926206.1 1115625 D 595496 CDS YP_002926207.1 238900411 7952956 1116023..1116682 1 NC_012759.1 MG1655 equivalent: b1180; hypothetical protein 1116682 ycgM 7952956 ycgM Escherichia coli BW2952 hypothetical protein YP_002926207.1 1116023 D 595496 CDS YP_002926208.1 238900412 7955091 1116759..1117220 1 NC_012759.1 MG1655 equivalent: b1181; hypothetical protein 1117220 ycgN 7955091 ycgN Escherichia coli BW2952 hypothetical protein YP_002926208.1 1116759 D 595496 CDS YP_002926209.1 238900413 7952957 complement(1117427..1118338) 1 NC_012759.1 Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E 1118338 hlyE 7952957 hlyE Escherichia coli BW2952 hemolysin E YP_002926209.1 1117427 R 595496 CDS YP_002926210.1 238900414 7953904 1118711..1119130 1 NC_012759.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1119130 umuD 7953904 umuD Escherichia coli BW2952 DNA polymerase V subunit UmuD YP_002926210.1 1118711 D 595496 CDS YP_002926211.1 238900415 7953329 1119130..1120398 1 NC_012759.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1120398 umuC 7953329 umuC Escherichia coli BW2952 DNA polymerase V subunit UmuC YP_002926211.1 1119130 D 595496 CDS YP_002926212.1 238900416 7953328 complement(1120444..1120974) 1 NC_012759.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1120974 dsbB 7953328 dsbB Escherichia coli BW2952 disulfide bond formation protein B YP_002926212.1 1120444 R 595496 CDS YP_002926213.1 238900417 7954458 complement(1121120..1122661) 1 NC_012759.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1122661 nhaB 7954458 nhaB Escherichia coli BW2952 sodium/proton antiporter YP_002926213.1 1121120 R 595496 CDS YP_002926214.1 238900418 7956055 1122882..1123601 1 NC_012759.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1123601 fadR 7956055 fadR Escherichia coli BW2952 fatty acid metabolism regulator YP_002926214.1 1122882 D 595496 CDS YP_002926215.1 238900419 7953425 complement(1123653..1125185) 1 NC_012759.1 MG1655 equivalent: b1188; SpoVR family protein 1125185 ycgB 7953425 ycgB Escherichia coli BW2952 SpoVR family protein YP_002926215.1 1123653 R 595496 CDS YP_002926216.1 238900420 7952788 1125515..1126813 1 NC_012759.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1126813 dadA 7952788 dadA Escherichia coli BW2952 D-amino acid dehydrogenase small subunit YP_002926216.1 1125515 D 595496 CDS YP_002926217.1 238900421 7953226 1126823..1127893 1 NC_012759.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1127893 dadX 7953226 dadX Escherichia coli BW2952 alanine racemase YP_002926217.1 1126823 D 595496 CDS YP_002926218.1 238900422 7952439 complement(1128279..1130015) 1 NC_012759.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1130015 cvrA 7952439 cvrA Escherichia coli BW2952 potassium/proton antiporter YP_002926218.1 1128279 R 595496 CDS YP_002926219.1 238900423 7954683 complement(1130110..1131024) 1 NC_012759.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1131024 ldcA 7954683 ldcA Escherichia coli BW2952 L,D-carboxypeptidase A YP_002926219.1 1130110 R 595496 CDS YP_002926220.1 238900424 7954105 1131124..1131735 1 NC_012759.1 MG1655 equivalent: b1193; lytic murein endotransglycosylase E 1131735 emtA 7954105 emtA Escherichia coli BW2952 lytic murein endotransglycosylase E YP_002926220.1 1131124 D 595496 CDS YP_002926221.1 238900425 7954188 complement(1131737..1132471) 1 NC_012759.1 MG1655 equivalent: b1194; protein involved in flagellar function 1132471 ycgR 7954188 ycgR Escherichia coli BW2952 protein involved in flagellar function YP_002926221.1 1131737 R 595496 CDS YP_002926222.1 238900426 7955794 1132672..1132926 1 NC_012759.1 MG1655 equivalent: b1195; putative inner membrane protein 1132926 ymgE 7955794 ymgE Escherichia coli BW2952 putative inner membrane protein YP_002926222.1 1132672 D 595496 CDS YP_002926223.1 238900427 7955035 1133104..1133544 1 NC_012759.1 MG1655 equivalent: b1196; hypothetical protein 1133544 ycgY 7955035 ycgY Escherichia coli BW2952 hypothetical protein YP_002926223.1 1133104 D 595496 CDS YP_002926224.1 238900428 7955462 complement(1133623..1135320) 1 NC_012759.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1135320 treA 7955462 treA Escherichia coli BW2952 trehalase YP_002926224.1 1133623 R 595496 CDS YP_002926225.1 238900429 7954502 complement(1135640..1137061) 1 NC_012759.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM 1137061 dhaM 7954502 dhaM Escherichia coli BW2952 dihydroxyacetone kinase subunit DhaM YP_002926225.1 1135640 R 595496 CDS YP_002926226.1 238900430 7953710 complement(1137069..1137701) 1 NC_012759.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1137701 dhaL 7953710 dhaL Escherichia coli BW2952 dihydroxyacetone kinase subunit DhaL YP_002926226.1 1137069 R 595496 CDS YP_002926227.1 238900431 7953257 complement(1137712..1138782) 1 NC_012759.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1138782 dhaK 7953257 dhaK Escherichia coli BW2952 dihydroxyacetone kinase subunit DhaK YP_002926227.1 1137712 R 595496 CDS YP_002926228.1 238900432 7953258 1139010..1140929 1 NC_012759.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1140929 dhaR 7953258 dhaR Escherichia coli BW2952 DNA-binding transcriptional regulator DhaR YP_002926228.1 1139010 D 595496 CDS YP_002926229.1 238900433 7954822 complement(1141029..1143896) 1 NC_012759.1 MG1655 equivalent: b1202; putative adhesin 1143896 ycgV 7954822 ycgV Escherichia coli BW2952 putative adhesin YP_002926229.1 1141029 R 595496 CDS YP_002926230.1 238900434 7954624 complement(1144665..1145756) 1 NC_012759.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1145756 ychF 7954624 ychF Escherichia coli BW2952 GTP-dependent nucleic acid-binding protein EngD YP_002926230.1 1144665 R 595496 CDS YP_002926231.1 238900435 7954941 complement(1145873..1146457) 1 NC_012759.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1146457 pth 7954941 pth Escherichia coli BW2952 peptidyl-tRNA hydrolase YP_002926231.1 1145873 R 595496 CDS YP_002926232.1 238900436 7954485 1146735..1147013 1 NC_012759.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1147013 ychH 7954485 ychH Escherichia coli BW2952 hypothetical protein YP_002926232.1 1146735 D 595496 CDS YP_002926233.1 238900437 7955036 complement(1147068..1148747) 1 NC_012759.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM 1148747 ychM 7955036 ychM Escherichia coli BW2952 putative sulfate transporter YchM YP_002926233.1 1147068 R 595496 CDS YP_002926234.1 238900438 7955655 complement(1148872..1149819) 1 NC_012759.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1149819 prs 7955655 prs Escherichia coli BW2952 ribose-phosphate pyrophosphokinase YP_002926234.1 1148872 R 595496 CDS YP_002926235.1 238900439 7954554 complement(1149970..1150821) 1 NC_012759.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1150821 ipk 7954554 ipk Escherichia coli BW2952 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002926235.1 1149970 R 595496 CDS YP_002926236.1 238900440 7952332 complement(1150821..1151444) 1 NC_012759.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1151444 lolB 7952332 lolB Escherichia coli BW2952 outer membrane lipoprotein LolB YP_002926236.1 1150821 R 595496 CDS YP_002926237.1 238900441 7952625 1151658..1152914 1 NC_012759.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1152914 hemA 7952625 hemA Escherichia coli BW2952 glutamyl-tRNA reductase YP_002926237.1 1151658 D 595496 CDS YP_002926238.1 238900442 7953831 1152956..1154038 1 NC_012759.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1154038 prfA 7953831 prfA Escherichia coli BW2952 peptide chain release factor 1 YP_002926238.1 1152956 D 595496 CDS YP_002926239.1 238900443 7954474 1154038..1154871 1 NC_012759.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1154871 prmC 7954474 prmC Escherichia coli BW2952 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002926239.1 1154038 D 595496 CDS YP_002926240.1 238900444 7954333 1154868..1155260 1 NC_012759.1 MG1655 equivalent: b1213; putative transcriptional regulator 1155260 ychQ 7954333 ychQ Escherichia coli BW2952 putative transcriptional regulator YP_002926240.1 1154868 D 595496 CDS YP_002926241.1 238900445 7955633 1155264..1156073 1 NC_012759.1 MG1655 equivalent: b1214; putative transcriptional regulator 1156073 ychA 7955633 ychA Escherichia coli BW2952 putative transcriptional regulator YP_002926241.1 1155264 D 595496 CDS YP_002926242.1 238900446 7955634 1156109..1156963 1 NC_012759.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1156963 kdsA 7955634 kdsA Escherichia coli BW2952 2-dehydro-3-deoxyphosphooctonate aldolase YP_002926242.1 1156109 D 595496 CDS YP_002926243.1 238900447 7952301 complement(1157112..1157219) 1 NC_012759.1 MG1655 equivalent: b4419; toxic polypeptide, small 1157219 ldrA 7952301 ldrA Escherichia coli BW2952 toxic polypeptide, small YP_002926243.1 1157112 R 595496 CDS YP_002926244.1 238900448 7952173 complement(1157647..1157754) 1 NC_012759.1 MG1655 equivalent: b4421; toxic polypeptide, small 1157754 ldrB 7952173 ldrB Escherichia coli BW2952 toxic polypeptide, small YP_002926244.1 1157647 R 595496 CDS YP_002926245.1 238900449 7952174 complement(1158182..1158289) 1 NC_012759.1 MG1655 equivalent: b4423; toxic polypeptide, small 1158289 ldrC 7952174 ldrC Escherichia coli BW2952 toxic polypeptide, small YP_002926245.1 1158182 R 595496 CDS YP_002926246.1 238900450 7952175 complement(1158693..1159793) 1 NC_012759.1 MG1655 equivalent: b1216; calcium/sodium:proton antiporter 1159793 chaA 7952175 chaA Escherichia coli BW2952 calcium/sodium:proton antiporter YP_002926246.1 1158693 R 595496 CDS YP_002926247.1 238900451 7952589 1160063..1160293 1 NC_012759.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1160293 chaB 7952589 chaB Escherichia coli BW2952 cation transport regulator YP_002926247.1 1160063 D 595496 CDS YP_002926248.1 238900452 7954682 1160451..1161146 1 NC_012759.1 MG1655 equivalent: b1218; regulatory protein for cation transport 1161146 chaC 7954682 chaC Escherichia coli BW2952 regulatory protein for cation transport YP_002926248.1 1160451 D 595496 CDS YP_002926249.1 238900453 7955930 complement(1161190..1161543) 1 NC_012759.1 MG1655 equivalent: b1219; hypothetical protein 1161543 ychN 7955930 ychN Escherichia coli BW2952 hypothetical protein YP_002926249.1 1161190 R 595496 CDS YP_002926250.1 238900454 7952789 1161728..1163122 1 NC_012759.1 MG1655 equivalent: b1220; hypothetical protein 1163122 ychO 7952789 ychO Escherichia coli BW2952 hypothetical protein YP_002926250.1 1161728 D 595496 CDS YP_002926251.1 238900455 7955085 complement(1163123..1163773) 1 NC_012759.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1163773 narL 7955085 narL Escherichia coli BW2952 transcriptional regulator NarL YP_002926251.1 1163123 R 595496 CDS YP_002926252.1 238900456 7953356 complement(1163766..1165562) 1 NC_012759.1 MG1655 equivalent: b1222; nitrate/nitrite sensor protein NarX 1165562 narX 7953356 narX Escherichia coli BW2952 nitrate/nitrite sensor protein NarX YP_002926252.1 1163766 R 595496 CDS YP_002926253.1 238900457 7956020 1165901..1167292 1 NC_012759.1 MG1655 equivalent: b1223; nitrate/nitrite transporter 1167292 narK 7956020 narK Escherichia coli BW2952 nitrate/nitrite transporter YP_002926253.1 1165901 D 595496 CDS YP_002926254.1 238900458 7954398 1167808..1171551 1 NC_012759.1 MG1655 equivalent: b1224; nitrate reductase 1 subunit alpha 1171551 narG 7954398 narG Escherichia coli BW2952 nitrate reductase 1 subunit alpha YP_002926254.1 1167808 D 595496 CDS YP_002926255.1 238900459 7954387 1171548..1173086 1 NC_012759.1 MG1655 equivalent: b1225; nitrate reductase 1, beta (Fe-S) subunit 1173086 narH 7954387 narH Escherichia coli BW2952 nitrate reductase 1, beta (Fe-S) subunit YP_002926255.1 1171548 D 595496 CDS YP_002926256.1 238900460 7954388 1173083..1173793 1 NC_012759.1 MG1655 equivalent: b1226; molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 1173793 narJ 7954388 narJ Escherichia coli BW2952 molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 YP_002926256.1 1173083 D 595496 CDS YP_002926257.1 238900461 7954286 1173793..1174470 1 NC_012759.1 MG1655 equivalent: b1227; nitrate reductase 1, gamma (cytochrome b(NR)) subunit 1174470 narI 7954286 narI Escherichia coli BW2952 nitrate reductase 1, gamma (cytochrome b(NR)) subunit YP_002926257.1 1173793 D 595496 CDS YP_002926258.1 238900462 7954389 1174653..1174928 1 NC_012759.1 MG1655 equivalent: b1228; hypothetical protein 1174928 ychS 7954389 ychS Escherichia coli BW2952 hypothetical protein YP_002926258.1 1174653 D 595496 CDS YP_002926259.1 238900463 7952080 complement(1175031..1175120) 1 NC_012759.1 MG1655 equivalent: b1229; putative protamine-like protein 1175120 tpr 7952080 tpr Escherichia coli BW2952 putative protamine-like protein YP_002926259.1 1175031 R 595496 CDS YP_002926260.1 238900464 7952052 complement(1175726..1176568) 1 NC_012759.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1176568 purU 7952052 purU Escherichia coli BW2952 formyltetrahydrofolate deformylase YP_002926260.1 1175726 R 595496 CDS YP_002926261.1 238900465 7953630 complement(1176618..1177076) 1 NC_012759.1 MG1655 equivalent: b1233; hypothetical protein 1177076 ychJ 7953630 ychJ Escherichia coli BW2952 hypothetical protein YP_002926261.1 1176618 R 595496 CDS YP_002926262.1 238900466 7952790 1177150..1178094 1 NC_012759.1 MG1655 equivalent: b1234; hypothetical protein 1178094 rssA 7952790 rssA Escherichia coli BW2952 hypothetical protein YP_002926262.1 1177150 D 595496 CDS YP_002926263.1 238900467 7952958 complement(1178223..1178726) 1 NC_012759.1 Insertion element IS1 1/5/6 protein insB 1178726 7952958 BWG_1061 Escherichia coli BW2952 Insertion element IS1 1/5/6 protein insB YP_002926263.1 1178223 R 595496 CDS YP_002926264.1 238900468 7954002 1179050..1179976 1 NC_012759.1 MG1655 equivalent: b1235; response regulator of RpoS 1179976 rssB 7954002 rssB Escherichia coli BW2952 response regulator of RpoS YP_002926264.1 1179050 D 595496 CDS YP_002926265.1 238900469 7955945 1180178..1181086 1 NC_012759.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1181086 galU 7955945 galU Escherichia coli BW2952 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_002926265.1 1180178 D 595496 CDS YP_002926266.1 238900470 7953808 complement(1181230..1181643) 1 NC_012759.1 MG1655 equivalent: b1237; global DNA-binding transcriptional dual regulator H-NS 1181643 hns 7953808 hns Escherichia coli BW2952 global DNA-binding transcriptional dual regulator H-NS YP_002926266.1 1181230 R 595496 CDS YP_002926267.1 238900471 7953789 1182248..1182865 1 NC_012759.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1182865 tdk 7953789 tdk Escherichia coli BW2952 thymidine kinase YP_002926267.1 1182248 D 595496 CDS YP_002926268.1 238900472 7956148 complement(1184167..1186842) 1 NC_012759.1 MG1655 equivalent: b1241; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1186842 adhE 7956148 adhE Escherichia coli BW2952 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002926268.1 1184167 R 595496 CDS YP_002926269.1 238900473 7953653 1187319..1187966 1 NC_012759.1 MG1655 equivalent: b1242; hypothetical protein 1187966 ychE 7953653 ychE Escherichia coli BW2952 hypothetical protein YP_002926269.1 1187319 D 595496 CDS YP_002926270.1 238900474 7955037 1188704..1190335 1 NC_012759.1 MG1655 equivalent: b1243; oligopeptide transporter subunit 1190335 oppA 7955037 oppA Escherichia coli BW2952 oligopeptide transporter subunit YP_002926270.1 1188704 D 595496 CDS YP_002926271.1 238900475 7954422 1190894..1191076 1 NC_012759.1 COG0428; Predicted divalent heavy-metal cations transporter 1191076 7954422 BWG_1070 Escherichia coli BW2952 Predicted divalent heavy-metal cations transporter YP_002926271.1 1190894 D 595496 CDS YP_002926272.1 238900476 7952648 1191063..1192013 1 NC_012759.1 CvaB, IS186 transposase 1192013 7952648 BWG_1071 Escherichia coli BW2952 CvaB, IS186 transposase YP_002926272.1 1191063 D 595496 CDS YP_002926273.1 238900477 7952212 1192707..1193615 1 NC_012759.1 MG1655 equivalent: b1245; oligopeptide transporter subunit 1193615 oppC 7952212 oppC Escherichia coli BW2952 oligopeptide transporter subunit YP_002926273.1 1192707 D 595496 CDS YP_002926274.1 238900478 7954424 1193627..1194640 1 NC_012759.1 MG1655 equivalent: b1246; oligopeptide ABC transporter ATP-binding protein 1194640 oppD 7954424 oppD Escherichia coli BW2952 oligopeptide ABC transporter ATP-binding protein YP_002926274.1 1193627 D 595496 CDS YP_002926275.1 238900479 7954425 1194637..1195641 1 NC_012759.1 MG1655 equivalent: b1247; oligopeptide transporter subunit 1195641 oppF 7954425 oppF Escherichia coli BW2952 oligopeptide transporter subunit YP_002926275.1 1194637 D 595496 CDS YP_002926276.1 238900480 7954426 complement(1195694..1196023) 1 NC_012759.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1196023 yciU 7954426 yciU Escherichia coli BW2952 dsDNA-mimic protein YP_002926276.1 1195694 R 595496 CDS YP_002926277.1 238900481 7955357 complement(1196058..1197518) 1 NC_012759.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1197518 cls 7955357 cls Escherichia coli BW2952 cardiolipin synthetase YP_002926277.1 1196058 R 595496 CDS YP_002926278.1 238900482 7952608 1197661..1197834 1 NC_012759.1 MG1655 equivalent: b4595; hypothetical protein 1197834 yciY 7952608 yciY Escherichia coli BW2952 hypothetical protein YP_002926278.1 1197661 D 595496 CDS YP_002926279.1 238900483 7953978 complement(1197889..1199142) 1 NC_012759.1 MG1655 equivalent: b1250; voltage-gated potassium channel 1199142 kch 7953978 kch Escherichia coli BW2952 voltage-gated potassium channel YP_002926279.1 1197889 R 595496 CDS YP_002926280.1 238900484 7956275 complement(1199442..1199738) 1 NC_012759.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1199738 yciI 7956275 yciI Escherichia coli BW2952 YciI-like protein YP_002926280.1 1199442 R 595496 CDS YP_002926281.1 238900485 7954839 1199962..1200681 1 NC_012759.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1200681 tonB 7954839 tonB Escherichia coli BW2952 transporter YP_002926281.1 1199962 D 595496 CDS YP_002926282.1 238900486 7954237 complement(1200721..1201119) 1 NC_012759.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1201119 yciA 7954237 yciA Escherichia coli BW2952 acyl-CoA thioester hydrolase YP_002926282.1 1200721 R 595496 CDS YP_002926283.1 238900487 7954954 complement(1201224..1201763) 1 NC_012759.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1201763 yciB 7954954 yciB Escherichia coli BW2952 intracellular septation protein A YP_002926283.1 1201224 R 595496 CDS YP_002926284.1 238900488 7954993 complement(1201793..1202536) 1 NC_012759.1 MG1655 equivalent: b1255; hypothetical protein 1202536 yciC 7954993 yciC Escherichia coli BW2952 hypothetical protein YP_002926284.1 1201793 R 595496 CDS YP_002926285.1 238900489 7954994 1202893..1203531 1 NC_012759.1 receptor for colicin S4; outer membrane protein W 1203531 ompW 7954994 ompW Escherichia coli BW2952 outer membrane protein W YP_002926285.1 1202893 D 595496 CDS YP_002926286.1 238900490 7954450 complement(1203591..1204097) 1 NC_012759.1 MG1655 equivalent: b1257; hypothetical protein 1204097 yciE 7954450 yciE Escherichia coli BW2952 hypothetical protein YP_002926286.1 1203591 R 595496 CDS YP_002926287.1 238900491 7952791 complement(1204143..1204643) 1 NC_012759.1 MG1655 equivalent: b1258; hypothetical protein 1204643 yciF 7952791 yciF Escherichia coli BW2952 hypothetical protein YP_002926287.1 1204143 R 595496 CDS YP_002926288.1 238900492 7952792 complement(1204729..1204908) 1 NC_012759.1 MG1655 equivalent: b1259; hypothetical protein 1204908 yciG 7952792 yciG Escherichia coli BW2952 hypothetical protein YP_002926288.1 1204729 R 595496 CDS YP_002926289.1 238900493 7955358 complement(1205289..1206095) 1 NC_012759.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1206095 trpA 7955358 trpA Escherichia coli BW2952 tryptophan synthase subunit alpha YP_002926289.1 1205289 R 595496 CDS YP_002926290.1 238900494 7956211 complement(1206095..1207288) 1 NC_012759.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1207288 trpB 7956211 trpB Escherichia coli BW2952 tryptophan synthase subunit beta YP_002926290.1 1206095 R 595496 CDS YP_002926291.1 238900495 7956212 complement(1207300..1208658) 1 NC_012759.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1208658 trpC 7956212 trpC Escherichia coli BW2952 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002926291.1 1207300 R 595496 CDS YP_002926292.1 238900496 7953689 complement(1208662..1210257) 1 NC_012759.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1210257 trpD 7953689 trpD Escherichia coli BW2952 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_002926292.1 1208662 R 595496 CDS YP_002926293.1 238900497 7953683 complement(1210257..1211819) 1 NC_012759.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1211819 trpE 7953683 trpE Escherichia coli BW2952 anthranilate synthase component I YP_002926293.1 1210257 R 595496 CDS YP_002926295.1 238900499 7956209 1212093..1212974 1 NC_012759.1 MG1655 equivalent: b1266; hypothetical protein 1212974 trpH 7956209 trpH Escherichia coli BW2952 hypothetical protein YP_002926295.1 1212093 D 595496 CDS YP_002926296.1 238900500 7952959 1212971..1213591 1 NC_012759.1 MG1655 equivalent: b1267; hypothetical protein 1213591 yciO 7952959 yciO Escherichia coli BW2952 hypothetical protein YP_002926296.1 1212971 D 595496 CDS YP_002926297.1 238900501 7952960 1213619..1215514 1 NC_012759.1 MG1655 equivalent: b1268; putative inner membrane protein 1215514 yciQ 7952960 yciQ Escherichia coli BW2952 putative inner membrane protein YP_002926297.1 1213619 D 595496 CDS YP_002926298.1 238900502 7955038 1215725..1216600 1 NC_012759.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1216600 rluB 7955038 rluB Escherichia coli BW2952 23S rRNA pseudouridylate synthase B YP_002926298.1 1215725 D 595496 CDS YP_002926299.1 238900503 7952250 complement(1216640..1217230) 1 NC_012759.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1217230 btuR 7952250 btuR Escherichia coli BW2952 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002926299.1 1216640 R 595496 CDS YP_002926300.1 238900504 7952646 complement(1217227..1217985) 1 NC_012759.1 MG1655 equivalent: b1271; short chain dehydrogenase 1217985 yciK 7952646 yciK Escherichia coli BW2952 short chain dehydrogenase YP_002926300.1 1217227 R 595496 CDS YP_002926301.1 238900505 7955268 1218205..1219254 1 NC_012759.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1219254 sohB 7955268 sohB Escherichia coli BW2952 putative periplasmic protease YP_002926301.1 1218205 D 595496 CDS YP_002926302.1 238900506 7954984 complement(1219290..1219541) 1 NC_012759.1 MG1655 equivalent: b1273; hypothetical protein 1219541 yciN 7954984 yciN Escherichia coli BW2952 hypothetical protein YP_002926302.1 1219290 R 595496 CDS YP_002926303.1 238900507 7955359 1219921..1222518 1 NC_012759.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1222518 topA 7955359 topA Escherichia coli BW2952 DNA topoisomerase I YP_002926303.1 1219921 D 595496 CDS YP_002926304.1 238900508 7953333 1222728..1223702 1 NC_012759.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1223702 cysB 7953333 cysB Escherichia coli BW2952 transcriptional regulator CysB YP_002926304.1 1222728 D 595496 CDS YP_002926305.1 238900509 7953435 1224033..1224161 1 NC_012759.1 MG1655 equivalent: b4522; hypothetical protein 1224161 ymiA 7953435 ymiA Escherichia coli BW2952 hypothetical protein YP_002926305.1 1224033 D 595496 CDS YP_002926306.1 238900510 7953973 1224164..1224331 1 NC_012759.1 MG1655 equivalent: b4523; hypothetical protein 1224331 yciX 7953973 yciX Escherichia coli BW2952 hypothetical protein YP_002926306.1 1224164 D 595496 CDS YP_002926307.1 238900511 7953974 1224704..1227379 1 NC_012759.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1227379 acnA 7953974 acnA Escherichia coli BW2952 aconitate hydratase YP_002926307.1 1224704 D 595496 CDS YP_002926308.1 238900512 7952411 complement(1227443..1228033) 1 NC_012759.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1228033 ribA 7952411 ribA Escherichia coli BW2952 GTP cyclohydrolase II YP_002926308.1 1227443 R 595496 CDS YP_002926309.1 238900513 7953875 1228203..1228967 1 NC_012759.1 MG1655 equivalent: b1278; phosphatidylglycerophosphatase B 1228967 pgpB 7953875 pgpB Escherichia coli BW2952 phosphatidylglycerophosphatase B YP_002926309.1 1228203 D 595496 CDS YP_002926310.1 238900514 7954523 1229116..1229424 1 NC_012759.1 MG1655 equivalent: b1279; hypothetical protein 1229424 yciS 7954523 yciS Escherichia coli BW2952 hypothetical protein YP_002926310.1 1229116 D 595496 CDS YP_002926311.1 238900515 7952706 1229431..1230600 1 NC_012759.1 MG1655 equivalent: b1280; hypothetical protein 1230600 yciM 7952706 yciM Escherichia coli BW2952 hypothetical protein YP_002926311.1 1229431 D 595496 CDS YP_002926312.1 238900516 7952961 1230794..1231531 1 NC_012759.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1231531 pyrF 7952961 pyrF Escherichia coli BW2952 orotidine 5'-phosphate decarboxylase YP_002926312.1 1230794 D 595496 CDS YP_002926313.1 238900517 7954432 1231531..1231857 1 NC_012759.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1231857 yciH 7954432 yciH Escherichia coli BW2952 translation initiation factor Sui1 YP_002926313.1 1231531 D 595496 CDS YP_002926314.1 238900518 7952962 complement(1231983..1232201) 1 NC_012759.1 MG1655 equivalent: b1283; lipoprotein 1232201 osmB 7952962 osmB Escherichia coli BW2952 lipoprotein YP_002926314.1 1231983 R 595496 CDS YP_002926315.1 238900519 7954155 complement(1232470..1233219) 1 NC_012759.1 MG1655 equivalent: b1284; putative DNA-binding transcriptional regulator 1233219 yciT 7954155 yciT Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926315.1 1232470 R 595496 CDS YP_002926316.1 238900520 7954754 complement(1233309..1233482) 1 NC_012759.1 MG1655 equivalent: b4596; hypothetical protein 1233482 yciZ 7954754 yciZ Escherichia coli BW2952 hypothetical protein YP_002926316.1 1233309 R 595496 CDS YP_002926317.1 238900521 7953965 complement(1233630..1235615) 1 NC_012759.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1235615 gmr 7953965 gmr Escherichia coli BW2952 RNase II stability modulator YP_002926317.1 1233630 R 595496 CDS YP_002926318.1 238900522 7954280 complement(1235851..1237785) 1 NC_012759.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1237785 rnb 7954280 rnb Escherichia coli BW2952 exoribonuclease II YP_002926318.1 1235851 R 595496 CDS YP_002926319.1 238900523 7955962 complement(1237853..1238980) 1 NC_012759.1 MG1655 equivalent: b1287; putative oxidoreductase 1238980 yciW 7955962 yciW Escherichia coli BW2952 putative oxidoreductase YP_002926319.1 1237853 R 595496 CDS YP_002926320.1 238900524 7955223 complement(1239124..1239912) 1 NC_012759.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 1239912 fabI 7955223 fabI Escherichia coli BW2952 enoyl-(acyl carrier protein) reductase YP_002926320.1 1239124 R 595496 CDS YP_002926321.1 238900525 7953523 complement(1240280..1240633) 1 NC_012759.1 MG1655 equivalent: b1289; hypothetical protein 1240633 ycjD 7953523 ycjD Escherichia coli BW2952 hypothetical protein YP_002926321.1 1240280 R 595496 CDS YP_002926322.1 238900526 7952793 complement(1240701..1241507) 1 NC_012759.1 MG1655 equivalent: b1290; putative antimicrobial peptide transporter subunit 1241507 sapF 7952793 sapF Escherichia coli BW2952 putative antimicrobial peptide transporter subunit YP_002926322.1 1240701 R 595496 CDS YP_002926323.1 238900527 7954649 complement(1241509..1242501) 1 NC_012759.1 MG1655 equivalent: b1291; putative antimicrobial peptide transporter subunit 1242501 sapD 7954649 sapD Escherichia coli BW2952 putative antimicrobial peptide transporter subunit YP_002926323.1 1241509 R 595496 CDS YP_002926324.1 238900528 7954650 complement(1242501..1243391) 1 NC_012759.1 MG1655 equivalent: b1292; putative antimicrobial peptide transporter subunit 1243391 sapC 7954650 sapC Escherichia coli BW2952 putative antimicrobial peptide transporter subunit YP_002926324.1 1242501 R 595496 CDS YP_002926325.1 238900529 7954651 complement(1243378..1244343) 1 NC_012759.1 MG1655 equivalent: b1293; putative antimicrobial peptide transporter subunit 1244343 sapB 7954651 sapB Escherichia coli BW2952 putative antimicrobial peptide transporter subunit YP_002926325.1 1243378 R 595496 CDS YP_002926326.1 238900530 7954652 complement(1244340..1245983) 1 NC_012759.1 MG1655 equivalent: b1294; putative antimicrobial peptide transporter subunit 1245983 sapA 7954652 sapA Escherichia coli BW2952 putative antimicrobial peptide transporter subunit YP_002926326.1 1244340 R 595496 CDS YP_002926327.1 238900531 7954653 complement(1246296..1246541) 1 NC_012759.1 MG1655 equivalent: b1295; hypothetical protein 1246541 ymjA 7954653 ymjA Escherichia coli BW2952 hypothetical protein YP_002926327.1 1246296 R 595496 CDS YP_002926328.1 238900532 7955360 complement(1246675..1248060) 1 NC_012759.1 MG1655 equivalent: b1296; putrescine importer 1248060 puuP 7955360 puuP Escherichia coli BW2952 putrescine importer YP_002926328.1 1246675 R 595496 CDS YP_002926329.1 238900533 7955827 complement(1248363..1249781) 1 NC_012759.1 MG1655 equivalent: b1297; gamma-Glu-putrescine synthase 1249781 puuA 7955827 puuA Escherichia coli BW2952 gamma-Glu-putrescine synthase YP_002926329.1 1248363 R 595496 CDS YP_002926330.1 238900534 7953767 1249993..1250757 1 NC_012759.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1250757 puuD 7953767 puuD Escherichia coli BW2952 gamma-glutamyl-gamma-aminobutyrate hydrolase YP_002926330.1 1249993 D 595496 CDS YP_002926331.1 238900535 7953764 1250784..1251341 1 NC_012759.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1251341 puuR 7953764 puuR Escherichia coli BW2952 DNA-binding transcriptional repressor PuuR YP_002926331.1 1250784 D 595496 CDS YP_002926332.1 238900536 7953464 1251616..1253103 1 NC_012759.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1253103 puuC 7953464 puuC Escherichia coli BW2952 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_002926332.1 1251616 D 595496 CDS YP_002926333.1 238900537 7953765 1253105..1254385 1 NC_012759.1 MG1655 equivalent: b1301; gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding 1254385 puuB 7953765 puuB Escherichia coli BW2952 gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding YP_002926333.1 1253105 D 595496 CDS YP_002926334.1 238900538 7953766 1254423..1255688 1 NC_012759.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1255688 puuE 7953766 puuE Escherichia coli BW2952 4-aminobutyrate transaminase YP_002926334.1 1254423 D 595496 CDS YP_002926335.1 238900539 7953753 complement(1255808..1256785) 1 NC_012759.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1256785 pspF 7953753 pspF Escherichia coli BW2952 phage shock protein operon transcriptional activator YP_002926335.1 1255808 R 595496 CDS YP_002926336.1 238900540 7953364 1256952..1257620 1 NC_012759.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1257620 pspA 7953364 pspA Escherichia coli BW2952 phage shock protein PspA YP_002926336.1 1256952 D 595496 CDS YP_002926337.1 238900541 7955933 1257674..1257898 1 NC_012759.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1257898 pspB 7955933 pspB Escherichia coli BW2952 phage shock protein B YP_002926337.1 1257674 D 595496 CDS YP_002926338.1 238900542 7953446 1257898..1258257 1 NC_012759.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1258257 pspC 7953446 pspC Escherichia coli BW2952 DNA-binding transcriptional activator PspC YP_002926338.1 1257898 D 595496 CDS YP_002926339.1 238900543 7953379 1258266..1258487 1 NC_012759.1 MG1655 equivalent: b1307; peripheral inner membrane phage-shock protein 1258487 pspD 7953379 pspD Escherichia coli BW2952 peripheral inner membrane phage-shock protein YP_002926339.1 1258266 D 595496 CDS YP_002926340.1 238900544 7954486 1258562..1258876 1 NC_012759.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1258876 pspE 7954486 pspE Escherichia coli BW2952 thiosulfate:cyanide sulfurtransferase YP_002926340.1 1258562 D 595496 CDS YP_002926341.1 238900545 7956139 1259089..1260768 1 NC_012759.1 MG1655 equivalent: b1309; putative glucosyltransferase 1260768 ycjM 7956139 ycjM Escherichia coli BW2952 putative glucosyltransferase YP_002926341.1 1259089 D 595496 CDS YP_002926342.1 238900546 7954921 1260782..1262074 1 NC_012759.1 MG1655 equivalent: b1310; putative sugar transporter subunit: periplasmic-binding component of ABC superfamily 1262074 ycjN 7954921 ycjN Escherichia coli BW2952 putative sugar transporter subunit: periplasmic-binding component of ABC superfamily YP_002926342.1 1260782 D 595496 CDS YP_002926343.1 238900547 7955610 1262095..1262976 1 NC_012759.1 MG1655 equivalent: b1311; putative sugar transporter subunit: membrane component of ABC superfamily 1262976 ycjO 7955610 ycjO Escherichia coli BW2952 putative sugar transporter subunit: membrane component of ABC superfamily YP_002926343.1 1262095 D 595496 CDS YP_002926344.1 238900548 7955607 1262963..1263805 1 NC_012759.1 MG1655 equivalent: b1312; putative sugar transporter subunit: membrane component of ABC superfamily 1263805 ycjP 7955607 ycjP Escherichia coli BW2952 putative sugar transporter subunit: membrane component of ABC superfamily YP_002926344.1 1262963 D 595496 CDS YP_002926345.1 238900549 7955613 1263836..1264888 1 NC_012759.1 MG1655 equivalent: b1313; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1264888 ycjQ 7955613 ycjQ Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002926345.1 1263836 D 595496 CDS YP_002926346.1 238900550 7955263 1264907..1265695 1 NC_012759.1 MG1655 equivalent: b1314; putative enzyme 1265695 ycjR 7955263 ycjR Escherichia coli BW2952 putative enzyme YP_002926346.1 1264907 D 595496 CDS YP_002926347.1 238900551 7954843 1265705..1266760 1 NC_012759.1 MG1655 equivalent: b1315; putative oxidoreductase, NADH-binding 1266760 ycjS 7954843 ycjS Escherichia coli BW2952 putative oxidoreductase, NADH-binding YP_002926347.1 1265705 D 595496 CDS YP_002926348.1 238900552 7955256 1266757..1269024 1 NC_012759.1 MG1655 equivalent: b1316; putative hydrolase 1269024 ycjT 7955256 ycjT Escherichia coli BW2952 putative hydrolase YP_002926348.1 1266757 D 595496 CDS YP_002926349.1 238900553 7954964 1269021..1269680 1 NC_012759.1 MG1655 equivalent: b1317; putative beta-phosphoglucomutase 1269680 ycjU 7954964 ycjU Escherichia coli BW2952 putative beta-phosphoglucomutase YP_002926349.1 1269021 D 595496 CDS YP_002926350.1 238900554 7954669 1270820..1271725 1 NC_012759.1 MG1655 equivalent: b1319; outer membrane porin 1271725 ompG 7954669 ompG Escherichia coli BW2952 outer membrane porin YP_002926350.1 1270820 D 595496 CDS YP_002926351.1 238900555 7954444 complement(1271836..1272834) 1 NC_012759.1 MG1655 equivalent: b1320; putative DNA-binding transcriptional regulator 1272834 ycjW 7954444 ycjW Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926351.1 1271836 R 595496 CDS YP_002926352.1 238900556 7954755 1272990..1274387 1 NC_012759.1 MG1655 equivalent: b1321; hypothetical protein 1274387 ycjX 7954755 ycjX Escherichia coli BW2952 hypothetical protein YP_002926352.1 1272990 D 595496 CDS YP_002926353.1 238900557 7953090 1274384..1275445 1 NC_012759.1 MG1655 equivalent: b1322; hypothetical protein 1275445 ycjF 7953090 ycjF Escherichia coli BW2952 hypothetical protein YP_002926353.1 1274384 D 595496 CDS YP_002926354.1 238900558 7952707 1275593..1277134 1 NC_012759.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1277134 tyrR 7952707 tyrR Escherichia coli BW2952 DNA-binding transcriptional regulator TyrR YP_002926354.1 1275593 D 595496 CDS YP_002926355.1 238900559 7953437 complement(1277178..1277684) 1 NC_012759.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1277684 tpx 7953437 tpx Escherichia coli BW2952 thiol peroxidase YP_002926355.1 1277178 R 595496 CDS YP_002926356.1 238900560 7954145 1277803..1278768 1 NC_012759.1 MG1655 equivalent: b1325; L-Ala-D/L-Glu epimerase 1278768 ycjG 7954145 ycjG Escherichia coli BW2952 L-Ala-D/L-Glu epimerase YP_002926356.1 1277803 D 595496 CDS YP_002926357.1 238900561 7954108 complement(1278743..1279531) 1 NC_012759.1 MG1655 equivalent: b1326; murein peptide amidase A 1279531 mpaA 7954108 mpaA Escherichia coli BW2952 murein peptide amidase A YP_002926357.1 1278743 R 595496 CDS YP_002926358.1 238900562 7954322 complement(1279806..1280738) 1 NC_012759.1 MG1655 equivalent: b1327; putative hydrolase 1280738 ycjY 7954322 ycjY Escherichia coli BW2952 putative hydrolase YP_002926358.1 1279806 R 595496 CDS YP_002926359.1 238900563 7954955 1280864..1281763 1 NC_012759.1 MG1655 equivalent: b1328; putative DNA-binding transcriptional regulator 1281763 ycjZ 7954955 ycjZ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926359.1 1280864 D 595496 CDS YP_002926360.1 238900564 7954795 1282100..1283713 1 NC_012759.1 MG1655 equivalent: b1329; murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit 1283713 mppA 7954795 mppA Escherichia coli BW2952 murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit YP_002926360.1 1282100 D 595496 CDS YP_002926361.1 238900565 7954323 complement(1283764..1284795) 1 NC_012759.1 MG1655 equivalent: b1330; hypothetical protein 1284795 ynaI 7954323 ynaI Escherichia coli BW2952 hypothetical protein YP_002926361.1 1283764 R 595496 CDS YP_002926362.1 238900566 7952669 1284949..1285965 1 NC_012759.1 MG1655 equivalent: b1331; IS5 transposase and trans-activator 1285965 insH 7952669 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002926362.1 1284949 D 595496 CDS YP_002926363.1 238900567 7954045 1286238..1286495 1 NC_012759.1 MG1655 equivalent: b1332; putative inner membrane protein 1286495 ynaJ 7954045 ynaJ Escherichia coli BW2952 putative inner membrane protein YP_002926363.1 1286238 D 595496 CDS YP_002926364.1 238900568 7955039 complement(1286545..1287495) 1 NC_012759.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1287495 uspE 7955039 uspE Escherichia coli BW2952 universal stress protein UspE YP_002926364.1 1286545 R 595496 CDS YP_002926365.1 238900569 7956072 complement(1287647..1288399) 1 NC_012759.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1288399 fnr 7956072 fnr Escherichia coli BW2952 fumarate/nitrate reduction transcriptional regulator YP_002926365.1 1287647 R 595496 CDS YP_002926366.1 238900570 7956180 complement(1289804..1290319) 1 NC_012759.1 MG1655 equivalent: b1335; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1290319 ogt 7956180 ogt Escherichia coli BW2952 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_002926366.1 1289804 R 595496 CDS YP_002926367.1 238900571 7954416 complement(1290330..1291856) 1 NC_012759.1 MG1655 equivalent: b1336; putative aminobenzoyl-glutamate transporter 1291856 abgT 7954416 abgT Escherichia coli BW2952 putative aminobenzoyl-glutamate transporter YP_002926367.1 1290330 R 595496 CDS YP_002926368.1 238900572 7954702 complement(1291893..1293338) 1 NC_012759.1 MG1655 equivalent: b1337; putative peptidase, aminobenzoyl-glutamate utilization protein 1293338 abgB 7954702 abgB Escherichia coli BW2952 putative peptidase, aminobenzoyl-glutamate utilization protein YP_002926368.1 1291893 R 595496 CDS YP_002926369.1 238900573 7955290 complement(1293338..1294648) 1 NC_012759.1 MG1655 equivalent: b1338; putative peptidase, aminobenzoyl-glutamate utilization protein 1294648 abgA 7955290 abgA Escherichia coli BW2952 putative peptidase, aminobenzoyl-glutamate utilization protein YP_002926369.1 1293338 R 595496 CDS YP_002926370.1 238900574 7955291 1294824..1295732 1 NC_012759.1 MG1655 equivalent: b1339; putative DNA-binding transcriptional regulator 1295732 abgR 7955291 abgR Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926370.1 1294824 D 595496 CDS YP_002926371.1 238900575 7952081 1296062..1296625 1 NC_012759.1 MG1655 equivalent: b1340; hypothetical protein 1296625 ydaL 7952081 ydaL Escherichia coli BW2952 hypothetical protein YP_002926371.1 1296062 D 595496 CDS YP_002926372.1 238900576 7952963 complement(1296646..1297878) 1 NC_012759.1 MG1655 equivalent: b1341; diguanylate cyclase 1297878 ydaM 7952963 ydaM Escherichia coli BW2952 diguanylate cyclase YP_002926372.1 1296646 R 595496 CDS YP_002926373.1 238900577 7954733 1298133..1299116 1 NC_012759.1 MG1655 equivalent: b1342; zinc transporter 1299116 zntB 7954733 zntB Escherichia coli BW2952 zinc transporter YP_002926373.1 1298133 D 595496 CDS YP_002926374.1 238900578 7955756 1299594..1300967 1 NC_012759.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1300967 dbpA 7955756 dbpA Escherichia coli BW2952 ATP-dependent RNA helicase DbpA YP_002926374.1 1299594 D 595496 CDS YP_002926375.1 238900579 7952537 complement(1301096..1302031) 1 NC_012759.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1302031 ttcA 7952537 ttcA Escherichia coli BW2952 C32 tRNA thiolase YP_002926375.1 1301096 R 595496 CDS YP_002926376.1 238900580 7954672 complement(1302083..1303318) 1 NC_012759.1 MG1655 equivalent: b1345; Rac prophage; integrase 1303318 intR 7954672 intR Escherichia coli BW2952 Rac prophage; integrase YP_002926376.1 1302083 R 595496 CDS YP_002926377.1 238900581 7955896 complement(1303320..1303535) 1 NC_012759.1 MG1655 equivalent: b1346; Rac prophage protein 1303535 ydaQ 7955896 ydaQ Escherichia coli BW2952 Rac prophage protein YP_002926377.1 1303320 R 595496 CDS YP_002926378.1 238900582 7955890 complement(1303614..1303823) 1 NC_012759.1 Rac prophage; hypothetical protein 1303823 ydaC 7955890 ydaC Escherichia coli BW2952 hypothetical protein YP_002926378.1 1303614 R 595496 CDS YP_002926379.1 238900583 7955904 complement(1303816..1304010) 1 NC_012759.1 seems to be involved in restriction alleviation and enhancement of modification by EcoKI, but not in restriction alleviation of type III restriction systems; Rac prophage; restriction alleviation and modification protein 1304010 lar 7955904 lar Escherichia coli BW2952 restriction alleviation and modification protein YP_002926379.1 1303816 R 595496 CDS YP_002926380.1 238900584 7955913 complement(1304067..1304876) 1 NC_012759.1 MG1655 equivalent: b1349; recombination and repair protein RecT 1304876 recT 7955913 recT Escherichia coli BW2952 recombination and repair protein RecT YP_002926380.1 1304067 R 595496 CDS YP_002926381.1 238900585 7955912 complement(1304869..1307469) 1 NC_012759.1 The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC.; exonuclease VIII 1307469 recE 7955912 recE Escherichia coli BW2952 exonuclease VIII YP_002926381.1 1304869 R 595496 CDS YP_002926382.1 238900586 7955894 complement(1307571..1307846) 1 NC_012759.1 Rac prophage hypothetical protein; hypothetical protein 1307846 racC 7955894 racC Escherichia coli BW2952 hypothetical protein YP_002926382.1 1307571 R 595496 CDS YP_002926383.1 238900587 7955905 complement(1307921..1308091) 1 NC_012759.1 MG1655 equivalent: b4526; Rac prophage protein 1308091 ydaE 7955905 ydaE Escherichia coli BW2952 Rac prophage protein YP_002926383.1 1307921 R 595496 CDS YP_002926384.1 238900588 7955891 complement(1308091..1308312) 1 NC_012759.1 Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division; FtsZ inhibitor protein 1308312 kil 7955891 kil Escherichia coli BW2952 FtsZ inhibitor protein YP_002926384.1 1308091 R 595496 CDS YP_002926385.1 238900589 7955895 1308754..1309242 1 NC_012759.1 MG1655 equivalent: b1353; Rac prophage; phage superinfection exclusion protein 1309242 sieB 7955895 sieB Escherichia coli BW2952 Rac prophage; phage superinfection exclusion protein YP_002926385.1 1308754 D 595496 CDS YP_002926386.1 238900590 7955897 complement(1309239..1309394) 1 NC_012759.1 MG1655 equivalent: b4527; Rac prophage protein 1309394 ydaF 7955897 ydaF Escherichia coli BW2952 Rac prophage protein YP_002926386.1 1309239 R 595496 CDS YP_002926387.1 238900591 7955907 complement(1309405..1309539) 1 NC_012759.1 MG1655 equivalent: b1355; Rac prophage protein 1309539 ydaG 7955907 ydaG Escherichia coli BW2952 Rac prophage protein YP_002926387.1 1309405 R 595496 CDS YP_002926388.1 238900592 7955906 complement(1309848..1310324) 1 NC_012759.1 MG1655 equivalent: b1356; Rac prophage; putative DNA-binding transcriptional regulator 1310324 racR 7955906 racR Escherichia coli BW2952 Rac prophage; putative DNA-binding transcriptional regulator YP_002926388.1 1309848 R 595496 CDS YP_002926389.1 238900593 7955900 1310448..1310744 1 NC_012759.1 MG1655 equivalent: b1357; Rac prophage; putative DNA-binding transcriptional regulator 1310744 ydaS 7955900 ydaS Escherichia coli BW2952 Rac prophage; putative DNA-binding transcriptional regulator YP_002926389.1 1310448 D 595496 CDS YP_002926390.1 238900594 7955902 1310767..1311189 1 NC_012759.1 MG1655 equivalent: b1358; Rac prophage protein 1311189 ydaT 7955902 ydaT Escherichia coli BW2952 Rac prophage protein YP_002926390.1 1310767 D 595496 CDS YP_002926391.1 238900595 7955908 1311202..1312059 1 NC_012759.1 MG1655 equivalent: b1359; Rac prophage protein 1312059 ydaU 7955908 ydaU Escherichia coli BW2952 Rac prophage protein YP_002926391.1 1311202 D 595496 CDS YP_002926392.1 238900596 7955892 1312066..1312812 1 NC_012759.1 MG1655 equivalent: b1360; putative replication protein 1312812 ydaV 7955892 ydaV Escherichia coli BW2952 putative replication protein YP_002926392.1 1312066 D 595496 CDS YP_002926393.1 238900597 7955899 1313483..1313668 1 NC_012759.1 MG1655 equivalent: b4528; Rac prophage; putative lipoprotein 1313668 rzoR 7955899 rzoR Escherichia coli BW2952 Rac prophage; putative lipoprotein YP_002926393.1 1313483 D 595496 CDS YP_002926394.1 238900598 7955903 1313865..1315322 1 NC_012759.1 MG1655 equivalent: b1363; Rac prophage; potassium transporter subunit 1315322 trkG 7955903 trkG Escherichia coli BW2952 Rac prophage; potassium transporter subunit YP_002926394.1 1313865 D 595496 CDS YP_002926395.1 238900599 7955898 1315460..1315723 1 NC_012759.1 MG1655 equivalent: b1365; Rac prophage protein 1315723 ynaK 7955898 ynaK Escherichia coli BW2952 Rac prophage protein YP_002926395.1 1315460 D 595496 CDS YP_002926396.1 238900600 7955893 complement(1317829..1318809) 1 NC_012759.1 MG1655 equivalent: b1370; IS5 transposase and trans-activator 1318809 insH 7955893 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002926396.1 1317829 R 595496 CDS YP_002926397.1 238900601 7954039 1319132..1322494 1 NC_012759.1 MG1655 equivalent: b1372; Rac prophage; putative tail fiber protein 1322494 stfR 7954039 stfR Escherichia coli BW2952 Rac prophage; putative tail fiber protein YP_002926397.1 1319132 D 595496 CDS YP_002926398.1 238900602 7955911 1322494..1323069 1 NC_012759.1 MG1655 equivalent: b1373; Rac prophage; putative tail fiber assembly protein 1323069 tfaR 7955911 tfaR Escherichia coli BW2952 Rac prophage; putative tail fiber assembly protein YP_002926398.1 1322494 D 595496 CDS YP_002926399.1 238900603 7955910 complement(1323167..1323757) 1 NC_012759.1 MG1655 equivalent: b1374; Rac prophage; putative site-specific recombinase 1323757 pinR 7955910 pinR Escherichia coli BW2952 Rac prophage; putative site-specific recombinase YP_002926399.1 1323167 R 595496 CDS YP_002926400.1 238900604 7955909 complement(1324074..1324340) 1 NC_012759.1 MG1655 equivalent: b1375; Rac prophage; putative DNA-binding transcriptional regulator 1324340 ynaE 7955909 ynaE Escherichia coli BW2952 Rac prophage; putative DNA-binding transcriptional regulator YP_002926400.1 1324074 R 595496 CDS YP_002926401.1 238900605 7955901 complement(1325268..1325702) 1 NC_012759.1 MG1655 equivalent: b1376; stress-induced protein, ATP-binding protein 1325702 uspF 7955901 uspF Escherichia coli BW2952 stress-induced protein, ATP-binding protein YP_002926401.1 1325268 R 595496 CDS YP_002926402.1 238900606 7956074 complement(1325843..1326976) 1 NC_012759.1 MG1655 equivalent: b1377; outer membrane pore protein N, non-specific 1326976 ompN 7956074 ompN Escherichia coli BW2952 outer membrane pore protein N, non-specific YP_002926402.1 1325843 R 595496 CDS YP_002926403.1 238900607 7952176 complement(1327343..1330867) 1 NC_012759.1 MG1655 equivalent: b1378; pyruvate-flavodoxin oxidoreductase 1330867 ydbK 7952176 ydbK Escherichia coli BW2952 pyruvate-flavodoxin oxidoreductase YP_002926403.1 1327343 R 595496 CDS YP_002926404.1 238900608 7953727 1331141..1331407 1 NC_012759.1 MG1655 equivalent: b4529; hypothetical protein 1331407 ydbJ 7953727 ydbJ Escherichia coli BW2952 hypothetical protein YP_002926404.1 1331141 D 595496 CDS YP_002926405.1 238900609 7955528 complement(1331404..1331826) 1 NC_012759.1 MG1655 equivalent: b1379; heat-inducible protein 1331826 hslJ 7955528 hslJ Escherichia coli BW2952 heat-inducible protein YP_002926405.1 1331404 R 595496 CDS YP_002926406.1 238900610 7953895 complement(1331937..1332926) 1 NC_012759.1 MG1655 equivalent: b1380; fermentative D-lactate dehydrogenase, NAD-dependent 1332926 ldhA 7953895 ldhA Escherichia coli BW2952 fermentative D-lactate dehydrogenase, NAD-dependent YP_002926406.1 1331937 R 595496 CDS YP_002926407.1 238900611 7953563 1333134..1335773 1 NC_012759.1 MG1655 equivalent: b1381; hypothetical protein 1335773 ydbH 7953563 ydbH Escherichia coli BW2952 hypothetical protein YP_002926407.1 1333134 D 595496 CDS YP_002926408.1 238900612 7955464 1335770..1335955 1 NC_012759.1 MG1655 equivalent: b1382; putative lipoprotein 1335955 ynbE 7955464 ynbE Escherichia coli BW2952 putative lipoprotein YP_002926408.1 1335770 D 595496 CDS YP_002926409.1 238900613 7955114 1335963..1336289 1 NC_012759.1 MG1655 equivalent: b1383; hypothetical protein 1336289 ydbL 7955114 ydbL Escherichia coli BW2952 hypothetical protein YP_002926409.1 1335963 D 595496 CDS YP_002926410.1 238900614 7952964 complement(1336461..1337366) 1 NC_012759.1 activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 1337366 feaR 7952964 feaR Escherichia coli BW2952 DNA-binding transcriptional activator FeaR YP_002926410.1 1336461 R 595496 CDS YP_002926411.1 238900615 7953405 1337602..1339101 1 NC_012759.1 MG1655 equivalent: b1385; phenylacetaldehyde dehydrogenase 1339101 feaB 7953405 feaB Escherichia coli BW2952 phenylacetaldehyde dehydrogenase YP_002926411.1 1337602 D 595496 CDS YP_002926412.1 238900616 7954506 complement(1339159..1341432) 1 NC_012759.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 1341432 tynA 7954506 tynA Escherichia coli BW2952 tyramine oxidase YP_002926412.1 1339159 R 595496 CDS YP_002926413.1 238900617 7956220 complement(1341680..1343725) 1 NC_012759.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 1343725 maoC 7956220 maoC Escherichia coli BW2952 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_002926413.1 1341680 R 595496 CDS YP_002926414.1 238900618 7953656 1344010..1344939 1 NC_012759.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1344939 paaA 7953656 paaA Escherichia coli BW2952 phenylacetate-CoA oxygenase subunit PaaA YP_002926414.1 1344010 D 595496 CDS YP_002926415.1 238900619 7955167 1344951..1345238 1 NC_012759.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1345238 paaB 7955167 paaB Escherichia coli BW2952 phenylacetate-CoA oxygenase subunit PaaB YP_002926415.1 1344951 D 595496 CDS YP_002926416.1 238900620 7955168 1345247..1345993 1 NC_012759.1 MG1655 equivalent: b1390; putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1345993 paaC 7955168 paaC Escherichia coli BW2952 putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_002926416.1 1345247 D 595496 CDS YP_002926417.1 238900621 7955169 1346002..1346505 1 NC_012759.1 MG1655 equivalent: b1391; putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1346505 paaD 7955169 paaD Escherichia coli BW2952 putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_002926417.1 1346002 D 595496 CDS YP_002926418.1 238900622 7955170 1346513..1347583 1 NC_012759.1 MG1655 equivalent: b1392; putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1347583 paaE 7955170 paaE Escherichia coli BW2952 putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_002926418.1 1346513 D 595496 CDS YP_002926419.1 238900623 7955171 1347580..1348347 1 NC_012759.1 MG1655 equivalent: b1393; enoyl-CoA hydratase-isomerase 1348347 paaF 7955171 paaF Escherichia coli BW2952 enoyl-CoA hydratase-isomerase YP_002926419.1 1347580 D 595496 CDS YP_002926420.1 238900624 7953524 1348347..1349135 1 NC_012759.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1349135 paaG 7953524 paaG Escherichia coli BW2952 enoyl-CoA hydratase YP_002926420.1 1348347 D 595496 CDS YP_002926421.1 238900625 7952415 1349137..1350564 1 NC_012759.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1350564 paaH 7952415 paaH Escherichia coli BW2952 3-hydroxyacyl-CoA dehydrogenase YP_002926421.1 1349137 D 595496 CDS YP_002926422.1 238900626 7952304 1350554..1350976 1 NC_012759.1 MG1655 equivalent: b1396; putative thioesterase 1350976 paaI 7952304 paaI Escherichia coli BW2952 putative thioesterase YP_002926422.1 1350554 D 595496 CDS YP_002926423.1 238900627 7955620 1350976..1352181 1 NC_012759.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1352181 paaJ 7955620 paaJ Escherichia coli BW2952 beta-ketoadipyl CoA thiolase YP_002926423.1 1350976 D 595496 CDS YP_002926424.1 238900628 7954668 1352208..1353521 1 NC_012759.1 MG1655 equivalent: b1398; phenylacetyl-CoA ligase 1353521 paaK 7954668 paaK Escherichia coli BW2952 phenylacetyl-CoA ligase YP_002926424.1 1352208 D 595496 CDS YP_002926425.1 238900629 7954507 1353622..1354572 1 NC_012759.1 MG1655 equivalent: b1399; DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive 1354572 paaX 7954507 paaX Escherichia coli BW2952 DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive YP_002926425.1 1353622 D 595496 CDS YP_002926426.1 238900630 7953475 1354554..1355144 1 NC_012759.1 MG1655 equivalent: b1400; putative hexapeptide repeat acetyltransferase 1355144 paaY 7953475 paaY Escherichia coli BW2952 putative hexapeptide repeat acetyltransferase YP_002926426.1 1354554 D 595496 CDS YP_002926427.1 238900631 7954943 complement(1358004..1358909) 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 1358909 insD 7954943 insD Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002926427.1 1358004 R 595496 CDS YP_002926428.1 238900632 7954077 complement(1358867..1359232) 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 1359232 insC 7954077 insC Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002926428.1 1358867 R 595496 CDS YP_002926429.1 238900633 7954071 1359441..1360592 1 NC_012759.1 MG1655 equivalent: b1404; KpLE2 phage-like element; IS30 transposase 1360592 insI 7954071 insI Escherichia coli BW2952 KpLE2 phage-like element; IS30 transposase YP_002926429.1 1359441 D 595496 CDS YP_002926430.1 238900634 7954085 1364304..1365164 1 NC_012759.1 MG1655 equivalent: b1406; putative oxidoreductase 1365164 ydbC 7954085 ydbC Escherichia coli BW2952 putative oxidoreductase YP_002926430.1 1364304 D 595496 CDS YP_002926431.1 238900635 7955255 1365227..1367533 1 NC_012759.1 MG1655 equivalent: b1407; hypothetical protein 1367533 ydbD 7955255 ydbD Escherichia coli BW2952 hypothetical protein YP_002926431.1 1365227 D 595496 CDS YP_002926432.1 238900636 7955465 1367704..1368309 1 NC_012759.1 MG1655 equivalent: b1408; putative inner membrane protein 1368309 ynbA 7955465 ynbA Escherichia coli BW2952 putative inner membrane protein YP_002926432.1 1367704 D 595496 CDS YP_002926433.1 238900637 7955040 1368309..1369205 1 NC_012759.1 MG1655 equivalent: b1409; putative CDP-diglyceride synthase 1369205 ynbB 7955040 ynbB Escherichia coli BW2952 putative CDP-diglyceride synthase YP_002926433.1 1368309 D 595496 CDS YP_002926434.1 238900638 7954685 1369221..1370978 1 NC_012759.1 MG1655 equivalent: b1410; putative hydrolase 1370978 ynbC 7954685 ynbC Escherichia coli BW2952 putative hydrolase YP_002926434.1 1369221 D 595496 CDS YP_002926435.1 238900639 7954965 1370992..1372284 1 NC_012759.1 MG1655 equivalent: b1411; putative phosphatase, inner membrane protein 1372284 ynbD 7954965 ynbD Escherichia coli BW2952 putative phosphatase, inner membrane protein YP_002926435.1 1370992 D 595496 CDS YP_002926436.1 238900640 7955312 complement(1372338..1372943) 1 NC_012759.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1372943 azoR 7955312 azoR Escherichia coli BW2952 azoreductase YP_002926436.1 1372338 R 595496 CDS YP_002926437.1 238900641 7954369 1373144..1377046 1 NC_012759.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1377046 hrpA 7954369 hrpA Escherichia coli BW2952 ATP-dependent RNA helicase HrpA YP_002926437.1 1373144 D 595496 CDS YP_002926438.1 238900642 7952533 1377318..1378118 1 NC_012759.1 MG1655 equivalent: b1414; hypothetical protein 1378118 ydcF 7952533 ydcF Escherichia coli BW2952 hypothetical protein YP_002926438.1 1377318 D 595496 CDS YP_002926439.1 238900643 7952965 1378315..1379754 1 NC_012759.1 NAD-linked; aldehyde dehydrogenase A 1379754 aldA 7952965 aldA Escherichia coli BW2952 aldehyde dehydrogenase A YP_002926439.1 1378315 D 595496 CDS YP_002926440.1 238900644 7952443 1380985..1381515 1 NC_012759.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1381515 cybB 7952443 cybB Escherichia coli BW2952 cytochrome b561 YP_002926440.1 1380985 D 595496 CDS YP_002926441.1 238900645 7952082 1381760..1381933 1 NC_012759.1 MG1655 equivalent: b1419; hypothetical protein 1381933 ydcA 7952082 ydcA Escherichia coli BW2952 hypothetical protein YP_002926441.1 1381760 D 595496 CDS YP_002926442.1 238900646 7955466 complement(1382005..1382154) 1 NC_012759.1 MG1655 equivalent: b4428; small toxic polypeptide 1382154 hokB 7955466 hokB Escherichia coli BW2952 small toxic polypeptide YP_002926442.1 1382005 R 595496 CDS YP_002926443.1 238900647 7956156 complement(1382045..1382212) 1 NC_012759.1 MG1655 equivalent: b1420; regulatory peptide 1382212 mokB 7956156 mokB Escherichia coli BW2952 regulatory peptide YP_002926443.1 1382045 R 595496 CDS YP_002926444.1 238900648 7952177 1382553..1384193 1 NC_012759.1 MG1655 equivalent: b1421; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1384193 trg 7952177 trg Escherichia coli BW2952 methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor YP_002926444.1 1382553 D 595496 CDS YP_002926445.1 238900649 7954250 complement(1384231..1385154) 1 NC_012759.1 MG1655 equivalent: b1422; putative DNA-binding transcriptional regulator 1385154 ydcI 7954250 ydcI Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926445.1 1384231 R 595496 CDS YP_002926446.1 238900650 7954756 1385371..1386714 1 NC_012759.1 MG1655 equivalent: b1423; hypothetical protein 1386714 ydcJ 7954756 ydcJ Escherichia coli BW2952 hypothetical protein YP_002926446.1 1385371 D 595496 CDS YP_002926447.1 238900651 7952966 1386939..1388594 1 NC_012759.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1388594 mdoD 7952966 mdoD Escherichia coli BW2952 glucan biosynthesis protein D YP_002926447.1 1386939 D 595496 CDS YP_002926448.1 238900652 7953791 1388734..1388958 1 NC_012759.1 MG1655 equivalent: b1426; hypothetical protein 1388958 ydcH 7953791 ydcH Escherichia coli BW2952 hypothetical protein YP_002926448.1 1388734 D 595496 CDS YP_002926449.1 238900653 7955467 1389021..1389560 1 NC_012759.1 MG1655 equivalent: b1427; ribosomal-protein-L7/L12-serine acetyltransferase 1389560 rimL 7955467 rimL Escherichia coli BW2952 ribosomal-protein-L7/L12-serine acetyltransferase YP_002926449.1 1389021 D 595496 CDS YP_002926450.1 238900654 7955975 complement(1389552..1390532) 1 NC_012759.1 MG1655 equivalent: b1428; putative enzyme 1390532 ydcK 7955975 ydcK Escherichia coli BW2952 putative enzyme YP_002926450.1 1389552 R 595496 CDS YP_002926451.1 238900655 7954840 1390656..1391648 1 NC_012759.1 MG1655 equivalent: b1429; potassium-tellurite ethidium and proflavin transporter 1391648 tehA 7954840 tehA Escherichia coli BW2952 potassium-tellurite ethidium and proflavin transporter YP_002926451.1 1390656 D 595496 CDS YP_002926452.1 238900656 7954580 1391645..1392238 1 NC_012759.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1392238 tehB 7954580 tehB Escherichia coli BW2952 tellurite resistance protein TehB YP_002926452.1 1391645 D 595496 CDS YP_002926453.1 238900657 7955579 1392540..1393208 1 NC_012759.1 MG1655 equivalent: b1431; putative lipoprotein 1393208 ydcL 7955579 ydcL Escherichia coli BW2952 putative lipoprotein YP_002926453.1 1392540 D 595496 CDS YP_002926454.1 238900658 7955115 1393740..1394948 1 NC_012759.1 MG1655 equivalent: b1432; putative transposase 1394948 ydcM 7955115 ydcM Escherichia coli BW2952 putative transposase YP_002926454.1 1393740 D 595496 CDS YP_002926455.1 238900659 7955740 complement(1394988..1396163) 1 NC_012759.1 MG1655 equivalent: b1433; putative benzoate transporter 1396163 ydcO 7955740 ydcO Escherichia coli BW2952 putative benzoate transporter YP_002926455.1 1394988 R 595496 CDS YP_002926456.1 238900660 7954667 1396255..1396791 1 NC_012759.1 MG1655 equivalent: b1434; putative DNA-binding transcriptional regulator 1396791 ydcN 7954667 ydcN Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926456.1 1396255 D 595496 CDS YP_002926457.1 238900661 7954797 1396864..1398825 1 NC_012759.1 MG1655 equivalent: b1435; putative peptidase 1398825 ydcP 7954797 ydcP Escherichia coli BW2952 putative peptidase YP_002926457.1 1396864 D 595496 CDS YP_002926458.1 238900662 7955279 complement(1398917..1399147) 1 NC_012759.1 MG1655 equivalent: b1436; hypothetical protein 1399147 yncJ 7955279 yncJ Escherichia coli BW2952 hypothetical protein YP_002926458.1 1398917 R 595496 CDS YP_002926459.1 238900663 7955361 1399369..1399545 1 NC_012759.1 MG1655 equivalent: b4532; hypothetical protein 1399545 yncN 7955361 yncN Escherichia coli BW2952 hypothetical protein YP_002926459.1 1399369 D 595496 CDS YP_002926460.1 238900664 7955529 1399591..1400007 1 NC_012759.1 MG1655 equivalent: b1438; putative DNA-binding transcriptional regulator 1400007 ydcQ 7955529 ydcQ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926460.1 1399591 D 595496 CDS YP_002926461.1 238900665 7954798 1400086..1401492 1 NC_012759.1 MG1655 equivalent: b1439; fused putative DNA-binding transcriptional regulator/putative amino transferase 1401492 ydcR 7954798 ydcR Escherichia coli BW2952 fused putative DNA-binding transcriptional regulator/putative amino transferase YP_002926461.1 1400086 D 595496 CDS YP_002926462.1 238900666 7953711 1401737..1402882 1 NC_012759.1 MG1655 equivalent: b1440; putative spermidine/putrescine transporter subunit 1402882 ydcS 7953711 ydcS Escherichia coli BW2952 putative spermidine/putrescine transporter subunit YP_002926462.1 1401737 D 595496 CDS YP_002926463.1 238900667 7955594 1402900..1403913 1 NC_012759.1 MG1655 equivalent: b1441; putative spermidine/putrescine transporter subunit 1403913 ydcT 7955594 ydcT Escherichia coli BW2952 putative spermidine/putrescine transporter subunit YP_002926463.1 1402900 D 595496 CDS YP_002926464.1 238900668 7955595 1403914..1404855 1 NC_012759.1 MG1655 equivalent: b1442; putative spermidine/putrescine transporter subunit 1404855 ydcU 7955595 ydcU Escherichia coli BW2952 putative spermidine/putrescine transporter subunit YP_002926464.1 1403914 D 595496 CDS YP_002926465.1 238900669 7955596 1404845..1405639 1 NC_012759.1 MG1655 equivalent: b1443; putative spermidine/putrescine transporter subunit 1405639 ydcV 7955596 ydcV Escherichia coli BW2952 putative spermidine/putrescine transporter subunit YP_002926465.1 1404845 D 595496 CDS YP_002926466.1 238900670 7955597 1405661..1407085 1 NC_012759.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1407085 ydcW 7955597 ydcW Escherichia coli BW2952 gamma-aminobutyraldehyde dehydrogenase YP_002926466.1 1405661 D 595496 CDS YP_002926467.1 238900671 7954220 complement(1407182..1407277) 1 NC_012759.1 MG1655 equivalent: b4598; hypothetical protein 1407277 yncL 7954220 yncL Escherichia coli BW2952 hypothetical protein YP_002926467.1 1407182 R 595496 CDS YP_002926468.1 238900672 7953966 1407472..1407645 1 NC_012759.1 MG1655 equivalent: b1445; putative inner membrane protein 1407645 ydcX 7953966 ydcX Escherichia coli BW2952 putative inner membrane protein YP_002926468.1 1407472 D 595496 CDS YP_002926469.1 238900673 7955041 1407731..1407964 1 NC_012759.1 MG1655 equivalent: b1446; hypothetical protein 1407964 ydcY 7955041 ydcY Escherichia coli BW2952 hypothetical protein YP_002926469.1 1407731 D 595496 CDS YP_002926470.1 238900674 7955468 complement(1407965..1408414) 1 NC_012759.1 MG1655 equivalent: b1447; putative inner membrane protein 1408414 ydcZ 7955468 ydcZ Escherichia coli BW2952 putative inner membrane protein YP_002926470.1 1407965 R 595496 CDS YP_002926471.1 238900675 7954995 complement(1408411..1408929) 1 NC_012759.1 MG1655 equivalent: b1448; putative acyltransferase with acyl-CoA N-acyltransferase domain 1408929 yncA 7954995 yncA Escherichia coli BW2952 putative acyltransferase with acyl-CoA N-acyltransferase domain YP_002926471.1 1408411 R 595496 CDS YP_002926472.1 238900676 7954615 1409086..1410147 1 NC_012759.1 MG1655 equivalent: b1449; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1410147 yncB 7954615 yncB Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002926472.1 1409086 D 595496 CDS YP_002926473.1 238900677 7955264 1410345..1411010 1 NC_012759.1 MG1655 equivalent: b1450; putative DNA-binding transcriptional regulator 1411010 yncC 7955264 yncC Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926473.1 1410345 D 595496 CDS YP_002926474.1 238900678 7954799 complement(1411046..1413148) 1 NC_012759.1 MG1655 equivalent: b1451; putative iron outer membrane transporter 1413148 yncD 7954799 yncD Escherichia coli BW2952 putative iron outer membrane transporter YP_002926474.1 1411046 R 595496 CDS YP_002926475.1 238900679 7955088 1413390..1414451 1 NC_012759.1 MG1655 equivalent: b1452; hypothetical protein 1414451 yncE 7955088 yncE Escherichia coli BW2952 hypothetical protein YP_002926475.1 1413390 D 595496 CDS YP_002926476.1 238900680 7952967 complement(1414564..1416063) 1 NC_012759.1 MG1655 equivalent: b1453; L-asparagine transporter 1416063 ansP 7952967 ansP Escherichia coli BW2952 L-asparagine transporter YP_002926476.1 1414564 R 595496 CDS YP_002926477.1 238900681 7954121 1416330..1416947 1 NC_012759.1 MG1655 equivalent: b1454; putative enzyme 1416947 yncG 7954121 yncG Escherichia coli BW2952 putative enzyme YP_002926477.1 1416330 D 595496 CDS YP_002926478.1 238900682 7954844 1417023..1417235 1 NC_012759.1 MG1655 equivalent: b1455; hypothetical protein 1417235 yncH 7954844 yncH Escherichia coli BW2952 hypothetical protein YP_002926478.1 1417023 D 595496 CDS YP_002926479.1 238900683 7955469 1420005..1420487 1 NC_012759.1 MG1655 equivalent: b1457; hypothetical protein 1420487 ydcD 7955469 ydcD Escherichia coli BW2952 hypothetical protein YP_002926479.1 1420005 D 595496 CDS YP_002926480.1 238900684 7955470 1421899..1423035 1 NC_012759.1 MG1655 equivalent: b1460; hypothetical protein 1423035 ydcC 7955470 ydcC Escherichia coli BW2952 hypothetical protein YP_002926480.1 1421899 D 595496 CDS YP_002926481.1 238900685 7952968 1423135..1423368 1 NC_012759.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1423368 pptA 7952968 pptA Escherichia coli BW2952 4-oxalocrotonate tautomerase YP_002926481.1 1423135 D 595496 CDS YP_002926482.1 238900686 7952335 complement(1423365..1423934) 1 NC_012759.1 MG1655 equivalent: b1462; hypothetical protein 1423934 yddH 7952335 yddH Escherichia coli BW2952 hypothetical protein YP_002926482.1 1423365 R 595496 CDS YP_002926483.1 238900687 7952794 1424107..1424952 1 NC_012759.1 MG1655 equivalent: b1463; N-hydroxyarylamine O-acetyltransferase 1424952 nhoA 7952794 nhoA Escherichia coli BW2952 N-hydroxyarylamine O-acetyltransferase YP_002926483.1 1424107 D 595496 CDS YP_002926484.1 238900688 7954376 complement(1425048..1425941) 1 NC_012759.1 MG1655 equivalent: b1464; hypothetical protein 1425941 yddE 7954376 yddE Escherichia coli BW2952 hypothetical protein YP_002926484.1 1425048 R 595496 CDS YP_002926485.1 238900689 7952795 complement(1426020..1426700) 1 NC_012759.1 MG1655 equivalent: b1465; nitrate reductase 2 (NRZ), gamma subunit 1426700 narV 7952795 narV Escherichia coli BW2952 nitrate reductase 2 (NRZ), gamma subunit YP_002926485.1 1426020 R 595496 CDS YP_002926486.1 238900690 7954393 complement(1426697..1427392) 1 NC_012759.1 MG1655 equivalent: b1466; nitrate reductase 2 (NRZ), delta subunit (assembly subunit) 1427392 narW 7954393 narW Escherichia coli BW2952 nitrate reductase 2 (NRZ), delta subunit (assembly subunit) YP_002926486.1 1426697 R 595496 CDS YP_002926487.1 238900691 7954392 complement(1427392..1428936) 1 NC_012759.1 MG1655 equivalent: b1467; nitrate reductase 2 (NRZ), beta subunit 1428936 narY 7954392 narY Escherichia coli BW2952 nitrate reductase 2 (NRZ), beta subunit YP_002926487.1 1427392 R 595496 CDS YP_002926488.1 238900692 7954391 complement(1428933..1432673) 1 NC_012759.1 MG1655 equivalent: b1468; nitrate reductase 2 (NRZ), alpha subunit 1432673 narZ 7954391 narZ Escherichia coli BW2952 nitrate reductase 2 (NRZ), alpha subunit YP_002926488.1 1428933 R 595496 CDS YP_002926489.1 238900693 7954390 complement(1432755..1434143) 1 NC_012759.1 MG1655 equivalent: b1469; nitrate/nitrite transporter 1434143 narU 7954390 narU Escherichia coli BW2952 nitrate/nitrite transporter YP_002926489.1 1432755 R 595496 CDS YP_002926490.1 238900694 7954397 complement(1434467..1434802) 1 NC_012759.1 MG1655 equivalent: b1470; hypothetical protein 1434802 yddJ 7954397 yddJ Escherichia coli BW2952 hypothetical protein YP_002926490.1 1434467 R 595496 CDS YP_002926491.1 238900695 7955362 complement(1436371..1437252) 1 NC_012759.1 MG1655 equivalent: b1473; hypothetical protein 1437252 yddG 7955362 yddG Escherichia coli BW2952 hypothetical protein YP_002926491.1 1436371 R 595496 CDS YP_002926492.1 238900696 7955150 1437484..1440531 1 NC_012759.1 MG1655 equivalent: b1474; formate dehydrogenase-N subunit alpha, nitrate-inducible 1440531 fdnG 7955150 fdnG Escherichia coli BW2952 formate dehydrogenase-N subunit alpha, nitrate-inducible YP_002926492.1 1437484 D 595496 CDS YP_002926493.1 238900697 7953619 1440544..1441428 1 NC_012759.1 MG1655 equivalent: b1475; formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible 1441428 fdnH 7953619 fdnH Escherichia coli BW2952 formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible YP_002926493.1 1440544 D 595496 CDS YP_002926494.1 238900698 7953621 1441421..1442074 1 NC_012759.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1442074 fdnI 7953621 fdnI Escherichia coli BW2952 formate dehydrogenase-N subunit gamma YP_002926494.1 1441421 D 595496 CDS YP_002926495.1 238900699 7953620 complement(1442481..1442765) 1 NC_012759.1 MG1655 equivalent: b1477; putative DNA-binding transcriptional regulator 1442765 yddM 7953620 yddM Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926495.1 1442481 R 595496 CDS YP_002926496.1 238900700 7954757 complement(1442911..1443921) 1 NC_012759.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1443921 adhP 7954757 adhP Escherichia coli BW2952 alcohol dehydrogenase YP_002926496.1 1442911 R 595496 CDS YP_002926497.1 238900701 7953533 complement(1444055..1445752) 1 NC_012759.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1445752 maeA 7953533 maeA Escherichia coli BW2952 malate dehydrogenase YP_002926497.1 1444055 R 595496 CDS YP_002926498.1 238900702 7954197 complement(1445909..1446046) 1 NC_012759.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1446046 rpsV 7954197 rpsV Escherichia coli BW2952 30S ribosomal subunit S22 YP_002926498.1 1445909 R 595496 CDS YP_002926499.1 238900703 7952286 complement(1446148..1446363) 1 NC_012759.1 MG1655 equivalent: b1481; biofilm-dependent modulation protein 1446363 bdm 7952286 bdm Escherichia coli BW2952 biofilm-dependent modulation protein YP_002926499.1 1446148 R 595496 CDS YP_002926500.1 238900704 7952578 1446708..1447139 1 NC_012759.1 MG1655 equivalent: b1482; osmotically inducible, stress-inducible membrane protein 1447139 osmC 7952578 osmC Escherichia coli BW2952 osmotically inducible, stress-inducible membrane protein YP_002926500.1 1446708 D 595496 CDS YP_002926501.1 238900705 7954434 complement(1447195..1448121) 1 NC_012759.1 MG1655 equivalent: b1483; D-ala-D-ala transporter subunit 1448121 ddpF 7954434 ddpF Escherichia coli BW2952 D-ala-D-ala transporter subunit YP_002926501.1 1447195 R 595496 CDS YP_002926502.1 238900706 7953210 complement(1448114..1449100) 1 NC_012759.1 MG1655 equivalent: b1484; D-ala-D-ala transporter subunit 1449100 ddpD 7953210 ddpD Escherichia coli BW2952 D-ala-D-ala transporter subunit YP_002926502.1 1448114 R 595496 CDS YP_002926503.1 238900707 7953211 complement(1449097..1449993) 1 NC_012759.1 MG1655 equivalent: b1485; ATP-dependent peptide transporter membrane subunit 1449993 ddpC 7953211 ddpC Escherichia coli BW2952 ATP-dependent peptide transporter membrane subunit YP_002926503.1 1449097 R 595496 CDS YP_002926504.1 238900708 7953212 complement(1449990..1451012) 1 NC_012759.1 MG1655 equivalent: b1486; D-ala-D-ala transporter subunit 1451012 ddpB 7953212 ddpB Escherichia coli BW2952 D-ala-D-ala transporter subunit YP_002926504.1 1449990 R 595496 CDS YP_002926505.1 238900709 7953213 complement(1451014..1452564) 1 NC_012759.1 MG1655 equivalent: b1487; D-ala-D-a la transporter subunit 1452564 ddpA 7953213 ddpA Escherichia coli BW2952 D-ala-D-a la transporter subunit YP_002926505.1 1451014 R 595496 CDS YP_002926506.1 238900710 7953208 complement(1452578..1453159) 1 NC_012759.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 1453159 ddpX 7953208 ddpX Escherichia coli BW2952 D-alanyl-D-alanine dipeptidase YP_002926506.1 1452578 R 595496 CDS YP_002926507.1 238900711 7953209 complement(1453417..1455816) 1 NC_012759.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1455816 dos 7953209 dos Escherichia coli BW2952 cAMP phosphodiesterase YP_002926507.1 1453417 R 595496 CDS YP_002926508.1 238900712 7952590 complement(1455841..1457223) 1 NC_012759.1 MG1655 equivalent: b1490; putative diguanylate cyclase 1457223 yddV 7952590 yddV Escherichia coli BW2952 putative diguanylate cyclase YP_002926508.1 1455841 R 595496 CDS YP_002926509.1 238900713 7954721 complement(1457587..1458906) 1 NC_012759.1 MG1655 equivalent: b1491; lipoprotein 1458906 yddW 7954721 yddW Escherichia coli BW2952 lipoprotein YP_002926509.1 1457587 R 595496 CDS YP_002926510.1 238900714 7955123 complement(1459037..1460572) 1 NC_012759.1 MG1655 equivalent: b1492; putative glutamate:gamma-aminobutyric acid antiporter 1460572 gadC 7955123 gadC Escherichia coli BW2952 putative glutamate:gamma-aminobutyric acid antiporter YP_002926510.1 1459037 R 595496 CDS YP_002926511.1 238900715 7954922 complement(1460728..1462128) 1 NC_012759.1 MG1655 equivalent: b1493; glutamate decarboxylase 1462128 gadB 7954922 gadB Escherichia coli BW2952 glutamate decarboxylase YP_002926511.1 1460728 R 595496 CDS YP_002926512.1 238900716 7953819 complement(1462490..1465285) 1 NC_012759.1 MG1655 equivalent: b1494; putative peptidase 1465285 pqqL 7953819 pqqL Escherichia coli BW2952 putative peptidase YP_002926512.1 1462490 R 595496 CDS YP_002926513.1 238900717 7955271 complement(1465330..1467702) 1 NC_012759.1 MG1655 equivalent: b1495; putative porin protein 1467702 yddB 7955271 yddB Escherichia coli BW2952 putative porin protein YP_002926513.1 1465330 R 595496 CDS YP_002926514.1 238900718 7955328 complement(1467740..1469425) 1 NC_012759.1 MG1655 equivalent: b1496; fused putative multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component 1469425 yddA 7955328 yddA Escherichia coli BW2952 fused putative multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component YP_002926514.1 1467740 R 595496 CDS YP_002926515.1 238900719 7953718 complement(1469716..1470873) 1 NC_012759.1 MG1655 equivalent: b1497; hypothetical protein 1470873 ydeM 7953718 ydeM Escherichia coli BW2952 hypothetical protein YP_002926515.1 1469716 R 595496 CDS YP_002926516.1 238900720 7952796 complement(1470925..1472607) 1 NC_012759.1 MG1655 equivalent: b1498; hypothetical protein 1472607 ydeN 7952796 ydeN Escherichia coli BW2952 hypothetical protein YP_002926516.1 1470925 R 595496 CDS YP_002926517.1 238900721 7952797 complement(1473009..1473770) 1 NC_012759.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1473770 ydeO 7952797 ydeO Escherichia coli BW2952 transcriptional regulator YdeO YP_002926517.1 1473009 R 595496 CDS YP_002926518.1 238900722 7954743 complement(1473845..1474042) 1 NC_012759.1 MG1655 equivalent: b1500; two component system connector membrane protein, EvgSA to PhoQP 1474042 yneN 7954743 yneN Escherichia coli BW2952 two component system connector membrane protein, EvgSA to PhoQP YP_002926518.1 1473845 R 595496 CDS YP_002926519.1 238900723 7956219 complement(1474290..1476569) 1 NC_012759.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase 1476569 ydeP 7956219 ydeP Escherichia coli BW2952 putative oxidoreductase YP_002926519.1 1474290 R 595496 CDS YP_002926520.1 238900724 7955224 complement(1476903..1477817) 1 NC_012759.1 MG1655 equivalent: b1502; putative fimbrial-like adhesin protein 1477817 ydeQ 7955224 ydeQ Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002926520.1 1476903 R 595496 CDS YP_002926521.1 238900725 7954883 complement(1477876..1478379) 1 NC_012759.1 MG1655 equivalent: b1503; putative fimbrial-like adhesin protein 1478379 ydeR 7954883 ydeR Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002926521.1 1477876 R 595496 CDS YP_002926522.1 238900726 7954884 complement(1478392..1478922) 1 NC_012759.1 MG1655 equivalent: b1504; putative fimbrial-like adhesin protein 1478922 ydeS 7954884 ydeS Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002926522.1 1478392 R 595496 CDS YP_002926523.1 238900727 7954885 complement(1480937..1482259) 1 NC_012759.1 MG1655 equivalent: b1507; regulator with hipB 1482259 hipA 7954885 hipA Escherichia coli BW2952 regulator with hipB YP_002926523.1 1480937 R 595496 CDS YP_002926524.1 238900728 7955927 complement(1482259..1482525) 1 NC_012759.1 MG1655 equivalent: b1508; DNA-binding transcriptional regulator HipB 1482525 hipB 7955927 hipB Escherichia coli BW2952 DNA-binding transcriptional regulator HipB YP_002926524.1 1482259 R 595496 CDS YP_002926525.1 238900729 7953439 complement(1482748..1484148) 1 NC_012759.1 MG1655 equivalent: b1509; hypothetical protein 1484148 ydeU 7953439 ydeU Escherichia coli BW2952 hypothetical protein YP_002926525.1 1482748 R 595496 CDS YP_002926526.1 238900730 7952798 complement(1484192..1488169) 1 NC_012759.1 MG1655 equivalent: b1510; putative lipoprotein 1488169 ydeK 7952798 ydeK Escherichia coli BW2952 putative lipoprotein YP_002926526.1 1484192 R 595496 CDS YP_002926527.1 238900731 7955107 complement(1488700..1490292) 1 NC_012759.1 MG1655 equivalent: b1511; autoinducer-2 (AI-2) kinase 1490292 lsrK 7955107 lsrK Escherichia coli BW2952 autoinducer-2 (AI-2) kinase YP_002926527.1 1488700 R 595496 CDS YP_002926528.1 238900732 7952538 complement(1490371..1491324) 1 NC_012759.1 MG1655 equivalent: b1512; lsr operon transcriptional repressor 1491324 lsrR 7952538 lsrR Escherichia coli BW2952 lsr operon transcriptional repressor YP_002926528.1 1490371 R 595496 CDS YP_002926529.1 238900733 7954173 1491573..1493108 1 NC_012759.1 MG1655 equivalent: b1513; fused AI2 transporter subunits of ABC superfamily: ATP-binding components 1493108 lsrA 7954173 lsrA Escherichia coli BW2952 fused AI2 transporter subunits of ABC superfamily: ATP-binding components YP_002926529.1 1491573 D 595496 CDS YP_002926530.1 238900734 7953655 1493102..1494130 1 NC_012759.1 MG1655 equivalent: b1514; AI2 transporter 1494130 lsrC 7953655 lsrC Escherichia coli BW2952 AI2 transporter YP_002926530.1 1493102 D 595496 CDS YP_002926531.1 238900735 7952435 1494130..1495122 1 NC_012759.1 MG1655 equivalent: b1515; AI2 transporter 1495122 lsrD 7952435 lsrD Escherichia coli BW2952 AI2 transporter YP_002926531.1 1494130 D 595496 CDS YP_002926532.1 238900736 7952436 1495134..1496156 1 NC_012759.1 MG1655 equivalent: b1516; AI2 transporter 1496156 lsrB 7952436 lsrB Escherichia coli BW2952 AI2 transporter YP_002926532.1 1495134 D 595496 CDS YP_002926533.1 238900737 7952437 1496183..1497058 1 NC_012759.1 MG1655 equivalent: b1517; aldolase 1497058 lsrF 7952437 lsrF Escherichia coli BW2952 aldolase YP_002926533.1 1496183 D 595496 CDS YP_002926534.1 238900738 7955826 1497082..1497372 1 NC_012759.1 MG1655 equivalent: b1518; autoinducer-2 (AI-2) modifying protein LsrG 1497372 lsrG 7955826 lsrG Escherichia coli BW2952 autoinducer-2 (AI-2) modifying protein LsrG YP_002926534.1 1497082 D 595496 CDS YP_002926535.1 238900739 7952539 1497429..1498187 1 NC_012759.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1498187 tam 7952539 tam Escherichia coli BW2952 trans-aconitate 2-methyltransferase YP_002926535.1 1497429 D 595496 CDS YP_002926536.1 238900740 7956163 complement(1498191..1499105) 1 NC_012759.1 MG1655 equivalent: b1520; hypothetical protein 1499105 yneE 7956163 yneE Escherichia coli BW2952 hypothetical protein YP_002926536.1 1498191 R 595496 CDS YP_002926537.1 238900741 7952670 complement(1499312..1500763) 1 NC_012759.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1500763 uxaB 7952670 uxaB Escherichia coli BW2952 altronate oxidoreductase YP_002926537.1 1499312 R 595496 CDS YP_002926538.1 238900742 7952462 complement(1500990..1501937) 1 NC_012759.1 MG1655 equivalent: b1522; putative diguanylate cyclase 1501937 yneF 7952462 yneF Escherichia coli BW2952 putative diguanylate cyclase YP_002926538.1 1500990 R 595496 CDS YP_002926539.1 238900743 7954722 complement(1502049..1502408) 1 NC_012759.1 MG1655 equivalent: b1523; hypothetical protein 1502408 yneG 7954722 yneG Escherichia coli BW2952 hypothetical protein YP_002926539.1 1502049 R 595496 CDS YP_002926540.1 238900744 7952799 complement(1502408..1503334) 1 NC_012759.1 catalyzes the formation of glutamate from glutamine; glutaminase 1503334 yneH 7952799 yneH Escherichia coli BW2952 glutaminase YP_002926540.1 1502408 R 595496 CDS YP_002926541.1 238900745 7954923 complement(1503398..1504786) 1 NC_012759.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate-semialdehyde dehydrogenase 1504786 sad 7954923 sad Escherichia coli BW2952 putative succinate-semialdehyde dehydrogenase YP_002926541.1 1503398 R 595496 CDS YP_002926542.1 238900746 7954627 1504887..1505768 1 NC_012759.1 MG1655 equivalent: b1526; putative DNA-binding transcriptional regulator 1505768 yneJ 7954627 yneJ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926542.1 1504887 D 595496 CDS YP_002926543.1 238900747 7954800 1505846..1506961 1 NC_012759.1 MG1655 equivalent: b1527; hypothetical protein 1506961 yneK 7954800 yneK Escherichia coli BW2952 hypothetical protein YP_002926543.1 1505846 D 595496 CDS YP_002926544.1 238900748 7955471 1507111..1508301 1 NC_012759.1 MG1655 equivalent: b1528; sugar efflux transporter 1508301 ydeA 7955471 ydeA Escherichia coli BW2952 sugar efflux transporter YP_002926544.1 1507111 D 595496 CDS YP_002926545.1 238900749 7954657 complement(1508326..1508991) 1 NC_012759.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1508991 marC 7954657 marC Escherichia coli BW2952 multiple drug resistance protein MarC YP_002926545.1 1508326 R 595496 CDS YP_002926546.1 238900750 7952800 1509203..1509637 1 NC_012759.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1509637 marR 7952800 marR Escherichia coli BW2952 DNA-binding transcriptional repressor MarR YP_002926546.1 1509203 D 595496 CDS YP_002926547.1 238900751 7953474 1509657..1510040 1 NC_012759.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1510040 marA 7953474 marA Escherichia coli BW2952 DNA-binding transcriptional activator MarA YP_002926547.1 1509657 D 595496 CDS YP_002926548.1 238900752 7953403 1510072..1510290 1 NC_012759.1 MG1655 equivalent: b1532; hypothetical protein 1510290 marB 7953403 marB Escherichia coli BW2952 hypothetical protein YP_002926548.1 1510072 D 595496 CDS YP_002926549.1 238900753 7955472 complement(1510321..1511220) 1 NC_012759.1 MG1655 equivalent: b1533; O-acetylserine/cysteine export protein 1511220 eamA 7955472 eamA Escherichia coli BW2952 O-acetylserine/cysteine export protein YP_002926549.1 1510321 R 595496 CDS YP_002926550.1 238900754 7953181 1511415..1512602 1 NC_012759.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 1512602 ydeE 7953181 ydeE Escherichia coli BW2952 putative MFS-type transporter YdeE YP_002926550.1 1511415 D 595496 CDS YP_002926551.1 238900755 7955685 1512729..1512824 1 NC_012759.1 MG1655 equivalent: b4599; hypothetical protein 1512824 yneM 7955685 yneM Escherichia coli BW2952 hypothetical protein YP_002926551.1 1512729 D 595496 CDS YP_002926552.1 238900756 7953979 complement(1513043..1513933) 1 NC_012759.1 MG1655 equivalent: b1535; hypothetical protein 1513933 ydeH 7953979 ydeH Escherichia coli BW2952 hypothetical protein YP_002926552.1 1513043 R 595496 CDS YP_002926553.1 238900757 7952801 complement(1514188..1514580) 1 NC_012759.1 MG1655 equivalent: b1536; hypothetical protein 1514580 ydeI 7952801 ydeI Escherichia coli BW2952 hypothetical protein YP_002926553.1 1514188 R 595496 CDS YP_002926554.1 238900758 7952802 1514856..1515374 1 NC_012759.1 MG1655 equivalent: b1537; competence damage-inducible protein A 1515374 ydeJ 7952802 ydeJ Escherichia coli BW2952 competence damage-inducible protein A YP_002926554.1 1514856 D 595496 CDS YP_002926555.1 238900759 7952969 complement(1515418..1517463) 1 NC_012759.1 MG1655 equivalent: b1538; dipeptidyl carboxypeptidase II 1517463 dcp 7952969 dcp Escherichia coli BW2952 dipeptidyl carboxypeptidase II YP_002926555.1 1515418 R 595496 CDS YP_002926556.1 238900760 7953269 1517600..1518346 1 NC_012759.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1518346 ydfG 7953269 ydfG Escherichia coli BW2952 3-hydroxy acid dehydrogenase YP_002926556.1 1517600 D 595496 CDS YP_002926557.1 238900761 7954110 1518435..1519121 1 NC_012759.1 MG1655 equivalent: b1540; putative DNA-binding transcriptional regulator 1519121 ydfH 7954110 ydfH Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926557.1 1518435 D 595496 CDS YP_002926558.1 238900762 7954801 1519298..1519501 1 NC_012759.1 MG1655 equivalent: b1541; hypothetical protein 1519501 ydfZ 7954801 ydfZ Escherichia coli BW2952 hypothetical protein YP_002926558.1 1519298 D 595496 CDS YP_002926559.1 238900763 7952970 complement(1519536..1520996) 1 NC_012759.1 MG1655 equivalent: b1542; putative mannonate dehydrogenase 1520996 ydfI 7952970 ydfI Escherichia coli BW2952 putative mannonate dehydrogenase YP_002926559.1 1519536 R 595496 CDS YP_002926560.1 238900764 7955133 1523122..1523388 1 NC_012759.1 MG1655 equivalent: b1544; Qin prophage; putative DNA-binding transcriptional regulator 1523388 ydfK 7955133 ydfK Escherichia coli BW2952 Qin prophage; putative DNA-binding transcriptional regulator YP_002926560.1 1523122 D 595496 CDS YP_002926561.1 238900765 7955862 1523705..1524295 1 NC_012759.1 MG1655 equivalent: b1545; Qin prophage; putative site-specific recombinase 1524295 pinQ 7955862 pinQ Escherichia coli BW2952 Qin prophage; putative site-specific recombinase YP_002926561.1 1523705 D 595496 CDS YP_002926562.1 238900766 7955880 complement(1524393..1524968) 1 NC_012759.1 MG1655 equivalent: b1546; Qin prophage; tail fiber assembly protein 1524968 tfaQ 7955880 tfaQ Escherichia coli BW2952 Qin prophage; tail fiber assembly protein YP_002926562.1 1524393 R 595496 CDS YP_002926563.1 238900767 7955881 complement(1524968..1525930) 1 NC_012759.1 MG1655 equivalent: b1547; Qin prophage; side tail fiber assembly protein 1525930 ydfN 7955881 ydfN Escherichia coli BW2952 Qin prophage; side tail fiber assembly protein YP_002926563.1 1524968 R 595496 CDS YP_002926564.1 238900768 7955879 1526839..1527072 1 NC_012759.1 MG1655 equivalent: b4533; hypothetical protein 1527072 ynfO 7955879 ynfO Escherichia coli BW2952 hypothetical protein YP_002926564.1 1526839 D 595496 CDS YP_002926565.1 238900769 7953987 1527130..1527540 1 NC_012759.1 MG1655 equivalent: b1549; Qin prophage protein 1527540 ydfO 7953987 ydfO Escherichia coli BW2952 Qin prophage protein YP_002926565.1 1527130 D 595496 CDS YP_002926566.1 238900770 7955871 complement(1527692..1527865) 1 NC_012759.1 MG1655 equivalent: b1550; Qin prophage protein 1527865 gnsB 7955871 gnsB Escherichia coli BW2952 Qin prophage protein YP_002926566.1 1527692 R 595496 CDS YP_002926567.1 238900771 7955864 complement(1528037..1528192) 1 NC_012759.1 MG1655 equivalent: b1551; Qin prophage protein 1528192 ynfN 7955864 ynfN Escherichia coli BW2952 Qin prophage protein YP_002926567.1 1528037 R 595496 CDS YP_002926568.1 238900772 7955865 complement(1528538..1528750) 1 NC_012759.1 MG1655 equivalent: b1552; Qin prophage; cold shock protein 1528750 cspI 7955865 cspI Escherichia coli BW2952 Qin prophage; cold shock protein YP_002926568.1 1528538 R 595496 CDS YP_002926569.1 238900773 7955856 complement(1529113..1529610) 1 NC_012759.1 MG1655 equivalent: b1553; Qin prophage protein 1529610 ydfP 7955856 ydfP Escherichia coli BW2952 Qin prophage protein YP_002926569.1 1529113 R 595496 CDS YP_002926570.1 238900774 7955859 complement(1529607..1530140) 1 NC_012759.1 MG1655 equivalent: b1554; Qin prophage; putative lysozyme 1530140 arrQ 7955859 arrQ Escherichia coli BW2952 Qin prophage; putative lysozyme YP_002926570.1 1529607 R 595496 CDS YP_002926571.1 238900775 7955863 complement(1530137..1530448) 1 NC_012759.1 MG1655 equivalent: b1555; Qin prophage protein 1530448 ydfR 7955863 ydfR Escherichia coli BW2952 Qin prophage protein YP_002926571.1 1530137 R 595496 CDS YP_002926572.1 238900776 7955866 complement(1530453..1530668) 1 NC_012759.1 MG1655 equivalent: b1556; Qin prophage; putative S lysis protein 1530668 essQ 7955866 essQ Escherichia coli BW2952 Qin prophage; putative S lysis protein YP_002926572.1 1530453 R 595496 CDS YP_002926573.1 238900777 7955878 complement(1531422..1531637) 1 NC_012759.1 MG1655 equivalent: b1557; Qin prophage; cold shock protein 1531637 cspB 7955878 cspB Escherichia coli BW2952 Qin prophage; cold shock protein YP_002926573.1 1531422 R 595496 CDS YP_002926574.1 238900778 7955857 1531938..1532150 1 NC_012759.1 MG1655 equivalent: b1558; Qin prophage; cold shock protein 1532150 cspF 7955857 cspF Escherichia coli BW2952 Qin prophage; cold shock protein YP_002926574.1 1531938 D 595496 CDS YP_002926575.1 238900779 7955858 complement(1532572..1533324) 1 NC_012759.1 MG1655 equivalent: b1559; Qin prophage; putative antitermination protein Q 1533324 quuQ 7955858 quuQ Escherichia coli BW2952 Qin prophage; putative antitermination protein Q YP_002926575.1 1532572 R 595496 CDS YP_002926576.1 238900780 7955861 complement(1533338..1534285) 1 NC_012759.1 MG1655 equivalent: b1560; Qin prophage protein 1534285 ydfU 7955861 ydfU Escherichia coli BW2952 Qin prophage protein YP_002926576.1 1533338 R 595496 CDS YP_002926577.1 238900781 7955867 complement(1534734..1534985) 1 NC_012759.1 MG1655 equivalent: b1561; Qin prophage protein 1534985 rem 7955867 rem Escherichia coli BW2952 Qin prophage protein YP_002926577.1 1534734 R 595496 CDS YP_002926578.1 238900782 7955868 complement(1535202..1535357) 1 NC_012759.1 MG1655 equivalent: b1562; Qin prophage; small toxic polypeptide 1535357 hokD 7955868 hokD Escherichia coli BW2952 Qin prophage; small toxic polypeptide YP_002926578.1 1535202 R 595496 CDS YP_002926579.1 238900783 7955882 complement(1535429..1535716) 1 NC_012759.1 MG1655 equivalent: b1563; Qin prophage; toxin of the RelE-RelB toxin-antitoxin system 1535716 relE 7955882 relE Escherichia coli BW2952 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system YP_002926579.1 1535429 R 595496 CDS YP_002926580.1 238900784 7955883 complement(1535716..1535955) 1 NC_012759.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 1535955 relB 7955883 relB Escherichia coli BW2952 bifunctional antitoxin/transcriptional repressor RelB YP_002926580.1 1535716 R 595496 CDS YP_002926581.1 238900785 7955854 1535980..1536285 1 NC_012759.1 MG1655 equivalent: b1565; Qin prophage protein 1536285 ydfV 7955854 ydfV Escherichia coli BW2952 Qin prophage protein YP_002926581.1 1535980 D 595496 CDS YP_002926582.1 238900786 7955872 1536488..1536820 1 NC_012759.1 MG1655 equivalent: b1566; Qin prophage protein 1536820 flxA 7955872 flxA Escherichia coli BW2952 Qin prophage protein YP_002926582.1 1536488 D 595496 CDS YP_002926583.1 238900787 7955873 complement(1537205..1537432) 1 NC_012759.1 MG1655 equivalent: b1567; Qin prophage protein 1537432 ydfW 7955873 ydfW Escherichia coli BW2952 Qin prophage protein YP_002926583.1 1537205 R 595496 CDS YP_002926584.1 238900788 7955869 complement(1537429..1537719) 1 NC_012759.1 MG1655 equivalent: b1568; Qin prophage protein 1537719 ydfX 7955869 ydfX Escherichia coli BW2952 Qin prophage protein YP_002926584.1 1537429 R 595496 CDS YP_002926585.1 238900789 7955870 complement(1537703..1537933) 1 NC_012759.1 MG1655 equivalent: b1569; DNA-binding transcriptional regulator DicC 1537933 dicC 7955870 dicC Escherichia coli BW2952 DNA-binding transcriptional regulator DicC YP_002926585.1 1537703 R 595496 CDS YP_002926586.1 238900790 7955860 1538017..1538424 1 NC_012759.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1538424 dicA 7955860 dicA Escherichia coli BW2952 transcriptional repressor DicA YP_002926586.1 1538017 D 595496 CDS YP_002926587.1 238900791 7955877 1538591..1538746 1 NC_012759.1 MG1655 equivalent: b1571; Qin prophage protein 1538746 ydfA 7955877 ydfA Escherichia coli BW2952 Qin prophage protein YP_002926587.1 1538591 D 595496 CDS YP_002926588.1 238900792 7955874 1538748..1538876 1 NC_012759.1 MG1655 equivalent: b1572; Qin prophage protein 1538876 ydfB 7955874 ydfB Escherichia coli BW2952 Qin prophage protein YP_002926588.1 1538748 D 595496 CDS YP_002926589.1 238900793 7952178 1539692..1539880 1 NC_012759.1 MG1655 equivalent: b1575; Qin prophage; cell division inhibition protein 1539880 dicB 7952178 dicB Escherichia coli BW2952 Qin prophage; cell division inhibition protein YP_002926589.1 1539692 D 595496 CDS YP_002926590.1 238900794 7955855 1539877..1540068 1 NC_012759.1 MG1655 equivalent: b1576; Qin prophage protein 1540068 ydfD 7955855 ydfD Escherichia coli BW2952 Qin prophage protein YP_002926590.1 1539877 D 595496 CDS YP_002926591.1 238900795 7955876 complement(1542979..1543998) 1 NC_012759.1 MG1655 equivalent: b1580; putative dehydrogenase 1543998 rspB 7955876 rspB Escherichia coli BW2952 putative dehydrogenase YP_002926591.1 1542979 R 595496 CDS YP_002926592.1 238900796 7955258 complement(1544010..1545224) 1 NC_012759.1 MG1655 equivalent: b1581; putative dehydratase 1545224 rspA 7955258 rspA Escherichia coli BW2952 putative dehydratase YP_002926592.1 1544010 R 595496 CDS YP_002926593.1 238900797 7954711 complement(1545430..1545756) 1 NC_012759.1 MG1655 equivalent: b1582; hypothetical protein 1545756 ynfA 7954711 ynfA Escherichia coli BW2952 hypothetical protein YP_002926593.1 1545430 R 595496 CDS YP_002926594.1 238900798 7952671 1545891..1546232 1 NC_012759.1 MG1655 equivalent: b1583; hypothetical protein 1546232 ynfB 7952671 ynfB Escherichia coli BW2952 hypothetical protein YP_002926594.1 1545891 D 595496 CDS YP_002926595.1 238900799 7955473 1546267..1546827 1 NC_012759.1 MG1655 equivalent: b1584; spermidine N1-acetyltransferase 1546827 speG 7955473 speG Escherichia coli BW2952 spermidine N1-acetyltransferase YP_002926595.1 1546267 D 595496 CDS YP_002926596.1 238900800 7956061 complement(1546830..1547540) 1 NC_012759.1 MG1655 equivalent: b1585; hypothetical protein 1547540 ynfC 7956061 ynfC Escherichia coli BW2952 hypothetical protein YP_002926596.1 1546830 R 595496 CDS YP_002926597.1 238900801 7955363 1547648..1547953 1 NC_012759.1 MG1655 equivalent: b1586; hypothetical protein 1547953 ynfD 7955363 ynfD Escherichia coli BW2952 hypothetical protein YP_002926597.1 1547648 D 595496 CDS YP_002926598.1 238900802 7955474 1548152..1550578 1 NC_012759.1 MG1655 equivalent: b1587; oxidoreductase subunit 1550578 ynfE 7955474 ynfE Escherichia coli BW2952 oxidoreductase subunit YP_002926598.1 1548152 D 595496 CDS YP_002926599.1 238900803 7954456 1550639..1553062 1 NC_012759.1 MG1655 equivalent: b1588; oxidoreductase subunit 1553062 ynfF 7954456 ynfF Escherichia coli BW2952 oxidoreductase subunit YP_002926599.1 1550639 D 595496 CDS YP_002926600.1 238900804 7954457 1553073..1553690 1 NC_012759.1 MG1655 equivalent: b1589; oxidoreductase, Fe-S subunit 1553690 ynfG 7954457 ynfG Escherichia coli BW2952 oxidoreductase, Fe-S subunit YP_002926600.1 1553073 D 595496 CDS YP_002926601.1 238900805 7954459 1553692..1554546 1 NC_012759.1 MG1655 equivalent: b1590; oxidoreductase, membrane subunit 1554546 ynfH 7954459 ynfH Escherichia coli BW2952 oxidoreductase, membrane subunit YP_002926601.1 1553692 D 595496 CDS YP_002926602.1 238900806 7954460 1554589..1555203 1 NC_012759.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1555203 dmsD 7954460 dmsD Escherichia coli BW2952 twin-argninine leader-binding protein DmsD YP_002926602.1 1554589 D 595496 CDS YP_002926603.1 238900807 7956218 1555398..1556654 1 NC_012759.1 MG1655 equivalent: b1592; putative voltage-gated ClC-type chloride channel ClcB 1556654 clcB 7956218 clcB Escherichia coli BW2952 putative voltage-gated ClC-type chloride channel ClcB YP_002926603.1 1555398 D 595496 CDS YP_002926604.1 238900808 7955749 complement(1556607..1557302) 1 NC_012759.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase 1557302 ynfK 7955749 ynfK Escherichia coli BW2952 putative dithiobiotin synthetase YP_002926604.1 1556607 R 595496 CDS YP_002926605.1 238900809 7954719 complement(1557427..1558647) 1 NC_012759.1 MG1655 equivalent: b1594; DNA-binding transcriptional repressor 1558647 dgsA 7954719 dgsA Escherichia coli BW2952 DNA-binding transcriptional repressor YP_002926605.1 1557427 R 595496 CDS YP_002926606.1 238900810 7953450 complement(1558782..1559675) 1 NC_012759.1 MG1655 equivalent: b1595; putative DNA-binding transcriptional regulator 1559675 ynfL 7953450 ynfL Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926606.1 1558782 R 595496 CDS YP_002926607.1 238900811 7954758 1559782..1561035 1 NC_012759.1 MG1655 equivalent: b1596; putative transporter 1561035 ynfM 7954758 ynfM Escherichia coli BW2952 putative transporter YP_002926607.1 1559782 D 595496 CDS YP_002926608.1 238900812 7955686 1561459..1561767 1 NC_012759.1 required for growth and survival under moderately acid conditions; acid shock protein 1561767 asr 7955686 asr Escherichia coli BW2952 acid shock protein YP_002926608.1 1561459 D 595496 CDS YP_002926609.1 238900813 7952408 1561860..1561943 1 NC_012759.1 MG1655 equivalent: b4601; membrane protein 1561943 ydgU 7952408 ydgU Escherichia coli BW2952 membrane protein YP_002926609.1 1561860 D 595496 CDS YP_002926610.1 238900814 7953980 1562043..1562864 1 NC_012759.1 MG1655 equivalent: b1598; putative peptidase 1562864 ydgD 7953980 ydgD Escherichia coli BW2952 putative peptidase YP_002926610.1 1562043 D 595496 CDS YP_002926611.1 238900815 7955280 complement(1562903..1563232) 1 NC_012759.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1563232 mdtI 7955280 mdtI Escherichia coli BW2952 multidrug efflux system protein MdtI YP_002926611.1 1562903 R 595496 CDS YP_002926612.1 238900816 7954308 complement(1563219..1563584) 1 NC_012759.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1563584 mdtJ 7954308 mdtJ Escherichia coli BW2952 multidrug efflux system protein MdtJ YP_002926612.1 1563219 R 595496 CDS YP_002926613.1 238900817 7954309 1563996..1565030 1 NC_012759.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 1565030 tqsA 7954309 tqsA Escherichia coli BW2952 putative transport protein YP_002926613.1 1563996 D 595496 CDS YP_002926614.1 238900818 7955042 complement(1565055..1566443) 1 NC_012759.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1566443 pntB 7955042 pntB Escherichia coli BW2952 pyridine nucleotide transhydrogenase YP_002926614.1 1565055 R 595496 CDS YP_002926615.1 238900819 7955836 complement(1566454..1567986) 1 NC_012759.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1567986 pntA 7955836 pntA Escherichia coli BW2952 NAD(P) transhydrogenase subunit alpha YP_002926615.1 1566454 R 595496 CDS YP_002926616.1 238900820 7955835 1568510..1569454 1 NC_012759.1 MG1655 equivalent: b1604; hypothetical protein 1569454 ydgH 7955835 ydgH Escherichia coli BW2952 hypothetical protein YP_002926616.1 1568510 D 595496 CDS YP_002926617.1 238900821 7955475 1569640..1571022 1 NC_012759.1 MG1655 equivalent: b1605; putative arginine/ornithine antiporter transporter 1571022 ydgI 7955475 ydgI Escherichia coli BW2952 putative arginine/ornithine antiporter transporter YP_002926617.1 1569640 D 595496 CDS YP_002926618.1 238900822 7954658 1571059..1571781 1 NC_012759.1 MG1655 equivalent: b1606; short chain dehydrogenase 1571781 folM 7954658 folM Escherichia coli BW2952 short chain dehydrogenase YP_002926618.1 1571059 D 595496 CDS YP_002926619.1 238900823 7953252 complement(1571778..1572113) 1 NC_012759.1 MG1655 equivalent: b1607; conserved inner membrane protein associated with alginate biosynthesis 1572113 ydgC 7953252 ydgC Escherichia coli BW2952 conserved inner membrane protein associated with alginate biosynthesis YP_002926619.1 1571778 R 595496 CDS YP_002926620.1 238900824 7952741 1572242..1572961 1 NC_012759.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1572961 rstA 7952741 rstA Escherichia coli BW2952 DNA-binding transcriptional regulator RstA YP_002926620.1 1572242 D 595496 CDS YP_002926621.1 238900825 7953361 1572965..1574266 1 NC_012759.1 MG1655 equivalent: b1609; sensor protein RstB 1574266 rstB 7953361 rstB Escherichia coli BW2952 sensor protein RstB YP_002926621.1 1572965 D 595496 CDS YP_002926622.1 238900826 7956025 1574342..1575271 1 NC_012759.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1575271 tus 7956025 tus Escherichia coli BW2952 DNA replication terminus site-binding protein YP_002926622.1 1574342 D 595496 CDS YP_002926623.1 238900827 7953994 complement(1575268..1576671) 1 NC_012759.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1576671 fumC 7953994 fumC Escherichia coli BW2952 fumarate hydratase YP_002926623.1 1575268 R 595496 CDS YP_002926624.1 238900828 7953643 complement(1576814..1578460) 1 NC_012759.1 MG1655 equivalent: b1612; fumarate hydratase (fumarase A), aerobic Class I 1578460 fumA 7953643 fumA Escherichia coli BW2952 fumarate hydratase (fumarase A), aerobic Class I YP_002926624.1 1576814 R 595496 CDS YP_002926625.1 238900829 7953642 1578659..1579834 1 NC_012759.1 MG1655 equivalent: b1613; mannose-6-phosphate isomerase 1579834 manA 7953642 manA Escherichia coli BW2952 mannose-6-phosphate isomerase YP_002926625.1 1578659 D 595496 CDS YP_002926626.1 238900830 7954215 1579935..1581443 1 NC_012759.1 MG1655 equivalent: b1614; hypothetical protein 1581443 ydgA 7954215 ydgA Escherichia coli BW2952 hypothetical protein YP_002926626.1 1579935 D 595496 CDS YP_002926627.1 238900831 7952971 complement(1581669..1582934) 1 NC_012759.1 MG1655 equivalent: b1615; putative outer membrane porin protein 1582934 uidC 7952971 uidC Escherichia coli BW2952 putative outer membrane porin protein YP_002926627.1 1581669 R 595496 CDS YP_002926628.1 238900832 7955208 complement(1584343..1586154) 1 NC_012759.1 MG1655 equivalent: b1617; beta-D-glucuronidase 1586154 uidA 7955208 uidA Escherichia coli BW2952 beta-D-glucuronidase YP_002926628.1 1584343 R 595496 CDS YP_002926629.1 238900833 7952547 complement(1586545..1587135) 1 NC_012759.1 MG1655 equivalent: b1618; DNA-binding transcriptional repressor 1587135 uidR 7952547 uidR Escherichia coli BW2952 DNA-binding transcriptional repressor YP_002926629.1 1586545 R 595496 CDS YP_002926630.1 238900834 7953451 complement(1587356..1588123) 1 NC_012759.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1588123 hdhA 7953451 hdhA Escherichia coli BW2952 7-alpha-hydroxysteroid dehydrogenase YP_002926630.1 1587356 R 595496 CDS YP_002926631.1 238900835 7952384 complement(1588235..1589263) 1 NC_012759.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1589263 malI 7952384 malI Escherichia coli BW2952 DNA-binding transcriptional repressor MalI YP_002926631.1 1588235 R 595496 CDS YP_002926632.1 238900836 7953452 1589438..1591030 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1591030 malX 7953452 malX Escherichia coli BW2952 bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_002926632.1 1589438 D 595496 CDS YP_002926633.1 238900837 7953696 1591040..1592212 1 NC_012759.1 MG1655 equivalent: b1622; bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon 1592212 malY 7953696 malY Escherichia coli BW2952 bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon YP_002926633.1 1591040 D 595496 CDS YP_002926634.1 238900838 7952562 1592316..1593317 1 NC_012759.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1593317 add 7952562 add Escherichia coli BW2952 adenosine deaminase YP_002926634.1 1592316 D 595496 CDS YP_002926635.1 238900839 7952421 complement(1593351..1594391) 1 NC_012759.1 MG1655 equivalent: b1624; putative oxidoreductase 1594391 ydgJ 7952421 ydgJ Escherichia coli BW2952 putative oxidoreductase YP_002926635.1 1593351 R 595496 CDS YP_002926636.1 238900840 7955225 1594634..1594759 1 NC_012759.1 MG1655 equivalent: b4409; beta-lactam resistance membrane protein 1594759 blr 7955225 blr Escherichia coli BW2952 beta-lactam resistance membrane protein YP_002926636.1 1594634 D 595496 CDS YP_002926637.1 238900841 7952551 1595032..1595247 1 NC_012759.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1595247 cnu 7952551 cnu Escherichia coli BW2952 oriC-binding nucleoid-associated protein YP_002926637.1 1595032 D 595496 CDS YP_002926638.1 238900842 7955560 1595333..1595773 1 NC_012759.1 MG1655 equivalent: b1626; hypothetical protein 1595773 ydgK 7955560 ydgK Escherichia coli BW2952 hypothetical protein YP_002926638.1 1595333 D 595496 CDS YP_002926639.1 238900843 7952708 1595850..1596431 1 NC_012759.1 MG1655 equivalent: b1627; Na(+)-translocating NADH-quinone reductase subunit E 1596431 rsxA 7952708 rsxA Escherichia coli BW2952 Na(+)-translocating NADH-quinone reductase subunit E YP_002926639.1 1595850 D 595496 CDS YP_002926640.1 238900844 7955079 1596431..1597009 1 NC_012759.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1597009 rsxB 7955079 rsxB Escherichia coli BW2952 electron transport complex protein RnfB YP_002926640.1 1596431 D 595496 CDS YP_002926641.1 238900845 7955089 1597002..1599224 1 NC_012759.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1599224 rsxC 7955089 rsxC Escherichia coli BW2952 electron transport complex protein RnfC YP_002926641.1 1597002 D 595496 CDS YP_002926642.1 238900846 7953707 1599225..1600283 1 NC_012759.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1600283 rnfD 7953707 rnfD Escherichia coli BW2952 electron transport complex protein RnfD YP_002926642.1 1599225 D 595496 CDS YP_002926643.1 238900847 7954983 1600287..1600907 1 NC_012759.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1600907 rsxG 7954983 rsxG Escherichia coli BW2952 electron transport complex protein RnfG YP_002926643.1 1600287 D 595496 CDS YP_002926644.1 238900848 7955232 1600911..1601606 1 NC_012759.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1601606 rsxE 7955232 rsxE Escherichia coli BW2952 electron transport complex protein RsxE YP_002926644.1 1600911 D 595496 CDS YP_002926645.1 238900849 7954982 1601606..1602241 1 NC_012759.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1602241 nth 7954982 nth Escherichia coli BW2952 endonuclease III YP_002926645.1 1601606 D 595496 CDS YP_002926646.1 238900850 7953305 1602852..1604354 1 NC_012759.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1604354 tppB 7953305 tppB Escherichia coli BW2952 putative tripeptide transporter permease YP_002926646.1 1602852 D 595496 CDS YP_002926647.1 238900851 7955687 1604460..1605065 1 NC_012759.1 MG1655 equivalent: b1635; glutathionine S-transferase 1605065 gst 7955687 gst Escherichia coli BW2952 glutathionine S-transferase YP_002926647.1 1604460 D 595496 CDS YP_002926648.1 238900852 7953841 complement(1605109..1605972) 1 NC_012759.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1605972 pdxY 7953841 pdxY Escherichia coli BW2952 pyridoxamine kinase YP_002926648.1 1605109 R 595496 CDS YP_002926649.1 238900853 7955838 complement(1606031..1607305) 1 NC_012759.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1607305 tyrS 7955838 tyrS Escherichia coli BW2952 tyrosyl-tRNA synthetase YP_002926649.1 1606031 R 595496 CDS YP_002926650.1 238900854 7956224 complement(1607434..1608090) 1 NC_012759.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1608090 pdxH 7956224 pdxH Escherichia coli BW2952 pyridoxamine 5'-phosphate oxidase YP_002926650.1 1607434 R 595496 CDS YP_002926651.1 238900855 7955840 complement(1608149..1608478) 1 NC_012759.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1608478 ydhA 7955840 ydhA Escherichia coli BW2952 lysozyme inhibitor YP_002926651.1 1608149 R 595496 CDS YP_002926652.1 238900856 7955108 complement(1608576..1609685) 1 NC_012759.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1609685 anmK 7955108 anmK Escherichia coli BW2952 anhydro-N-acetylmuramic acid kinase YP_002926652.1 1608576 R 595496 CDS YP_002926653.1 238900857 7952803 1609959..1610426 1 NC_012759.1 MG1655 equivalent: b1641; outer membrane lipoprotein 1610426 slyB 7952803 slyB Escherichia coli BW2952 outer membrane lipoprotein YP_002926653.1 1609959 D 595496 CDS YP_002926654.1 238900858 7954438 complement(1610473..1610907) 1 NC_012759.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1610907 slyA 7954438 slyA Escherichia coli BW2952 transcriptional regulator SlyA YP_002926654.1 1610473 R 595496 CDS YP_002926655.1 238900859 7953365 1611108..1611344 1 NC_012759.1 MG1655 equivalent: b1643; putative inner membrane protein 1611344 ydhI 7953365 ydhI Escherichia coli BW2952 putative inner membrane protein YP_002926655.1 1611108 D 595496 CDS YP_002926656.1 238900860 7955043 1611347..1612204 1 NC_012759.1 MG1655 equivalent: b1644; UDP pyrophosphate phosphatase 1612204 ydhJ 7955043 ydhJ Escherichia coli BW2952 UDP pyrophosphate phosphatase YP_002926656.1 1611347 D 595496 CDS YP_002926657.1 238900861 7956250 1612204..1614216 1 NC_012759.1 MG1655 equivalent: b1645; hypothetical protein 1614216 ydhK 7956250 ydhK Escherichia coli BW2952 hypothetical protein YP_002926657.1 1612204 D 595496 CDS YP_002926658.1 238900862 7952709 complement(1614217..1614738) 1 NC_012759.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1614738 sodC 7952709 sodC Escherichia coli BW2952 superoxide dismutase YP_002926658.1 1614217 R 595496 CDS YP_002926659.1 238900863 7956099 complement(1614819..1615715) 1 NC_012759.1 MG1655 equivalent: b1647; putative oxidoreductase 1615715 ydhF 7956099 ydhF Escherichia coli BW2952 putative oxidoreductase YP_002926659.1 1614819 R 595496 CDS YP_002926660.1 238900864 7955226 complement(1615764..1616003) 1 NC_012759.1 MG1655 equivalent: b1648; hypothetical protein 1616003 ydhL 7955226 ydhL Escherichia coli BW2952 hypothetical protein YP_002926660.1 1615764 R 595496 CDS YP_002926661.1 238900865 7952804 1616106..1616705 1 NC_012759.1 MG1655 equivalent: b1649; putative DNA-binding transcriptional regulator 1616705 ydhM 7952804 ydhM Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926661.1 1616106 D 595496 CDS YP_002926662.1 238900866 7954802 1616742..1617839 1 NC_012759.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1617839 nemA 7954802 nemA Escherichia coli BW2952 N-ethylmaleimide reductase YP_002926662.1 1616742 D 595496 CDS YP_002926663.1 238900867 7954372 1617920..1618327 1 NC_012759.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1618327 gloA 7954372 gloA Escherichia coli BW2952 glyoxalase I YP_002926663.1 1617920 D 595496 CDS YP_002926664.1 238900868 7953870 1618430..1619077 1 NC_012759.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1619077 rnt 7953870 rnt Escherichia coli BW2952 ribonuclease T YP_002926664.1 1618430 D 595496 CDS YP_002926665.1 238900869 7955963 1619170..1623786 1 NC_012759.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 1623786 lhr 7955963 lhr Escherichia coli BW2952 putative ATP-dependent helicase Lhr YP_002926665.1 1619170 D 595496 CDS YP_002926666.1 238900870 7954664 complement(1623837..1624184) 1 NC_012759.1 MG1655 equivalent: b1654; hypothetical protein 1624184 grxD 7954664 grxD Escherichia coli BW2952 hypothetical protein YP_002926666.1 1623837 R 595496 CDS YP_002926667.1 238900871 7952805 1624518..1625333 1 NC_012759.1 MG1655 equivalent: b1655; putative lipoprotein 1625333 ydhO 7952805 ydhO Escherichia coli BW2952 putative lipoprotein YP_002926667.1 1624518 D 595496 CDS YP_002926668.1 238900872 7955116 1625461..1626042 1 NC_012759.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1626042 sodB 7955116 sodB Escherichia coli BW2952 superoxide dismutase YP_002926668.1 1625461 D 595496 CDS YP_002926669.1 238900873 7956100 complement(1626204..1627373) 1 NC_012759.1 MG1655 equivalent: b1657; putative transporter 1627373 ydhP 7956100 ydhP Escherichia coli BW2952 putative transporter YP_002926669.1 1626204 R 595496 CDS YP_002926670.1 238900874 7955656 complement(1627539..1627628) 1 NC_012759.1 MG1655 equivalent: b4602; membrane protein 1627628 ynhF 7955656 ynhF Escherichia coli BW2952 membrane protein YP_002926670.1 1627539 R 595496 CDS YP_002926671.1 238900875 7953967 1627927..1628952 1 NC_012759.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1628952 purR 7953967 purR Escherichia coli BW2952 DNA-binding transcriptional repressor PurR YP_002926671.1 1627927 D 595496 CDS YP_002926672.1 238900876 7953478 complement(1628949..1629881) 1 NC_012759.1 MG1655 equivalent: b1659; putative DNA-binding transcriptional regulator 1629881 ydhB 7953478 ydhB Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926672.1 1628949 R 595496 CDS YP_002926673.1 238900877 7954759 1629994..1631205 1 NC_012759.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1631205 ydhC 7954759 ydhC Escherichia coli BW2952 inner membrane transport protein YdhC YP_002926673.1 1629994 D 595496 CDS YP_002926674.1 238900878 7955688 1631496..1632644 1 NC_012759.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1632644 cfa 7955688 cfa Escherichia coli BW2952 cyclopropane-fatty-acyl-phospholipid synthase YP_002926674.1 1631496 D 595496 CDS YP_002926675.1 238900879 7953178 complement(1632684..1633325) 1 NC_012759.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1633325 ribC 7953178 ribC Escherichia coli BW2952 riboflavin synthase subunit alpha YP_002926675.1 1632684 R 595496 CDS YP_002926676.1 238900880 7955954 1633540..1634913 1 NC_012759.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1634913 mdtK 7955954 mdtK Escherichia coli BW2952 multidrug efflux protein YP_002926676.1 1633540 D 595496 CDS YP_002926677.1 238900881 7954310 complement(1634954..1636210) 1 NC_012759.1 MG1655 equivalent: b1664; hypothetical protein 1636210 ydhQ 7954310 ydhQ Escherichia coli BW2952 hypothetical protein YP_002926677.1 1634954 R 595496 CDS YP_002926678.1 238900882 7952131 1636783..1637088 1 NC_012759.1 MG1655 equivalent: b1667; hypothetical protein 1637088 ydhR 7952131 ydhR Escherichia coli BW2952 hypothetical protein YP_002926678.1 1636783 D 595496 CDS YP_002926679.1 238900883 7955476 1637214..1638818 1 NC_012759.1 MG1655 equivalent: b1668; hypothetical protein 1638818 ydhS 7955476 ydhS Escherichia coli BW2952 hypothetical protein YP_002926679.1 1637214 D 595496 CDS YP_002926680.1 238900884 7953078 complement(1638830..1639642) 1 NC_012759.1 MG1655 equivalent: b1669; hypothetical protein 1639642 ydhT 7953078 ydhT Escherichia coli BW2952 hypothetical protein YP_002926680.1 1638830 R 595496 CDS YP_002926681.1 238900885 7952807 complement(1639646..1640431) 1 NC_012759.1 MG1655 equivalent: b1670; putative cytochrome 1640431 ydhU 7952807 ydhU Escherichia coli BW2952 putative cytochrome YP_002926681.1 1639646 R 595496 CDS YP_002926682.1 238900886 7954706 complement(1640428..1641147) 1 NC_012759.1 MG1655 equivalent: b1671; 4Fe-4S ferredoxin 1641147 ydhX 7954706 ydhX Escherichia coli BW2952 4Fe-4S ferredoxin YP_002926682.1 1640428 R 595496 CDS YP_002926683.1 238900887 7954594 complement(1641160..1641807) 1 NC_012759.1 MG1655 equivalent: b1672; hypothetical protein 1641807 ydhW 7954594 ydhW Escherichia coli BW2952 hypothetical protein YP_002926683.1 1641160 R 595496 CDS YP_002926684.1 238900888 7955364 complement(1641811..1643913) 1 NC_012759.1 MG1655 equivalent: b1673; putative oxidoreductase 1643913 ydhV 7955364 ydhV Escherichia coli BW2952 putative oxidoreductase YP_002926684.1 1641811 R 595496 CDS YP_002926685.1 238900889 7955227 complement(1643934..1644560) 1 NC_012759.1 MG1655 equivalent: b1674; hypothetical protein 1644560 ydhY 7955227 ydhY Escherichia coli BW2952 hypothetical protein YP_002926685.1 1643934 R 595496 CDS YP_002926686.1 238900890 7954595 complement(1645015..1645224) 1 NC_012759.1 MG1655 equivalent: b1675; hypothetical protein 1645224 ydhZ 7954595 ydhZ Escherichia coli BW2952 hypothetical protein YP_002926686.1 1645015 R 595496 CDS YP_002926687.1 238900891 7955365 1645781..1647193 1 NC_012759.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1647193 pykF 7955365 pykF Escherichia coli BW2952 pyruvate kinase YP_002926687.1 1645781 D 595496 CDS YP_002926688.1 238900892 7955852 1647504..1647740 1 NC_012759.1 MG1655 equivalent: b1677; murein lipoprotein 1647740 lpp 7955852 lpp Escherichia coli BW2952 murein lipoprotein YP_002926688.1 1647504 D 595496 CDS YP_002926689.1 238900893 7954321 complement(1647804..1648808) 1 NC_012759.1 MG1655 equivalent: b1678; hypothetical protein 1648808 ynhG 7954321 ynhG Escherichia coli BW2952 hypothetical protein YP_002926689.1 1647804 R 595496 CDS YP_002926690.1 238900894 7952808 complement(1648957..1649373) 1 NC_012759.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1649373 sufE 7952808 sufE Escherichia coli BW2952 cysteine desufuration protein SufE YP_002926690.1 1648957 R 595496 CDS YP_002926691.1 238900895 7956096 complement(1649386..1650606) 1 NC_012759.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1650606 sufS 7956096 sufS Escherichia coli BW2952 bifunctional cysteine desulfurase/selenocysteine lyase YP_002926691.1 1649386 R 595496 CDS YP_002926692.1 238900896 7956006 complement(1650603..1651874) 1 NC_012759.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1651874 sufD 7956006 sufD Escherichia coli BW2952 cysteine desulfurase activator complex subunit SufD YP_002926692.1 1650603 R 595496 CDS YP_002926693.1 238900897 7952659 complement(1651849..1652595) 1 NC_012759.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 1652595 sufC 7952659 sufC Escherichia coli BW2952 cysteine desulfurase YP_002926693.1 1651849 R 595496 CDS YP_002926694.1 238900898 7952661 complement(1652605..1654092) 1 NC_012759.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1654092 sufB 7952661 sufB Escherichia coli BW2952 cysteine desulfurase activator complex subunit SufB YP_002926694.1 1652605 R 595496 CDS YP_002926695.1 238900899 7952660 complement(1654101..1654469) 1 NC_012759.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1654469 sufA 7952660 sufA Escherichia coli BW2952 iron-sulfur cluster assembly scaffold protein YP_002926695.1 1654101 R 595496 CDS YP_002926696.1 238900900 7952083 complement(1655017..1655286) 1 NC_012759.1 MG1655 equivalent: b1685; hypothetical protein 1655286 ydiH 7952083 ydiH Escherichia coli BW2952 hypothetical protein YP_002926696.1 1655017 R 595496 CDS YP_002926697.1 238900901 7955366 complement(1655305..1655715) 1 NC_012759.1 MG1655 equivalent: b1686; hypothetical protein 1655715 ydiI 7955366 ydiI Escherichia coli BW2952 hypothetical protein YP_002926697.1 1655305 R 595496 CDS YP_002926698.1 238900902 7952809 complement(1655712..1658768) 1 NC_012759.1 MG1655 equivalent: b1687; putative FAD-linked oxidoreductase 1658768 ydiJ 7952809 ydiJ Escherichia coli BW2952 putative FAD-linked oxidoreductase YP_002926698.1 1655712 R 595496 CDS YP_002926699.1 238900903 7954868 1659157..1660269 1 NC_012759.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 1660269 ydiK 7954868 ydiK Escherichia coli BW2952 putative inner membrane protein YP_002926699.1 1659157 D 595496 CDS YP_002926700.1 238900904 7952179 1660698..1661054 1 NC_012759.1 MG1655 equivalent: b1689; hypothetical protein 1661054 ydiL 7952179 ydiL Escherichia coli BW2952 hypothetical protein YP_002926700.1 1660698 D 595496 CDS YP_002926701.1 238900905 7952972 1661154..1662368 1 NC_012759.1 MG1655 equivalent: b1690; putative transporter 1662368 ydiM 7952972 ydiM Escherichia coli BW2952 putative transporter YP_002926701.1 1661154 D 595496 CDS YP_002926702.1 238900906 7955689 1662589..1663860 1 NC_012759.1 MG1655 equivalent: b1691; putative transporter 1663860 ydiN 7955689 ydiN Escherichia coli BW2952 putative transporter YP_002926702.1 1662589 D 595496 CDS YP_002926703.1 238900907 7955690 1663872..1664738 1 NC_012759.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1664738 ydiB 7955690 ydiB Escherichia coli BW2952 quinate/shikimate dehydrogenase YP_002926703.1 1663872 D 595496 CDS YP_002926704.1 238900908 7955884 1664769..1665527 1 NC_012759.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1665527 aroD 7955884 aroD Escherichia coli BW2952 3-dehydroquinate dehydratase YP_002926704.1 1664769 D 595496 CDS YP_002926705.1 238900909 7952295 1665670..1667265 1 NC_012759.1 MG1655 equivalent: b1694; fused putative acetyl-CoA:acetoacetyl-CoA transferase: alpha subunit/beta subunit 1667265 ydiF 7952295 ydiF Escherichia coli BW2952 fused putative acetyl-CoA:acetoacetyl-CoA transferase: alpha subunit/beta subunit YP_002926705.1 1665670 D 595496 CDS YP_002926706.1 238900910 7953708 1667279..1668430 1 NC_012759.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 1668430 ydiO 7953708 ydiO Escherichia coli BW2952 putative acyl-CoA dehydrogenase YP_002926706.1 1667279 D 595496 CDS YP_002926707.1 238900911 7954609 complement(1668473..1669384) 1 NC_012759.1 MG1655 equivalent: b1696; putative DNA-binding transcriptional regulator 1669384 ydiP 7954609 ydiP Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926707.1 1668473 R 595496 CDS YP_002926708.1 238900912 7954760 1669700..1670464 1 NC_012759.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 1670464 ydiQ 7954760 ydiQ Escherichia coli BW2952 putative electron transfer flavoprotein YdiQ YP_002926708.1 1669700 D 595496 CDS YP_002926709.1 238900913 7952973 1670484..1671422 1 NC_012759.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1671422 ydiR 7952973 ydiR Escherichia coli BW2952 electron transfer flavoprotein subunit YdiR YP_002926709.1 1670484 D 595496 CDS YP_002926710.1 238900914 7954830 1671478..1672767 1 NC_012759.1 MG1655 equivalent: b1699; hypothetical protein 1672767 ydiS 7954830 ydiS Escherichia coli BW2952 hypothetical protein YP_002926710.1 1671478 D 595496 CDS YP_002926711.1 238900915 7955242 1672764..1673057 1 NC_012759.1 MG1655 equivalent: b1700; putative 4Fe-4S ferredoxin-type protein 1673057 ydiT 7955242 ydiT Escherichia coli BW2952 putative 4Fe-4S ferredoxin-type protein YP_002926711.1 1672764 D 595496 CDS YP_002926712.1 238900916 7954593 1673114..1674760 1 NC_012759.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1674760 fadK 7954593 fadK Escherichia coli BW2952 short chain acyl-CoA synthetase YP_002926712.1 1673114 D 595496 CDS YP_002926713.1 238900917 7956040 complement(1674817..1677195) 1 NC_012759.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1677195 pps 7956040 pps Escherichia coli BW2952 phosphoenolpyruvate synthase YP_002926713.1 1674817 R 595496 CDS YP_002926714.1 238900918 7954530 1677528..1678361 1 NC_012759.1 MG1655 equivalent: b1703; hypothetical protein 1678361 ydiA 7954530 ydiA Escherichia coli BW2952 hypothetical protein YP_002926714.1 1677528 D 595496 CDS YP_002926715.1 238900919 7952974 1678518..1679564 1 NC_012759.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1679564 aroH 7952974 aroH Escherichia coli BW2952 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002926715.1 1678518 D 595496 CDS YP_002926716.1 238900920 7952298 1679696..1679887 1 NC_012759.1 MG1655 equivalent: b1705; hypothetical protein 1679887 ydiE 7952298 ydiE Escherichia coli BW2952 hypothetical protein YP_002926716.1 1679696 D 595496 CDS YP_002926717.1 238900921 7952975 complement(1679891..1681327) 1 NC_012759.1 MG1655 equivalent: b1706; hypothetical protein 1681327 ydiU 7952975 ydiU Escherichia coli BW2952 hypothetical protein YP_002926717.1 1679891 R 595496 CDS YP_002926718.1 238900922 7952810 complement(1681390..1682103) 1 NC_012759.1 MG1655 equivalent: b1707; hypothetical protein 1682103 ydiV 7952810 ydiV Escherichia coli BW2952 hypothetical protein YP_002926718.1 1681390 R 595496 CDS YP_002926719.1 238900923 7952811 complement(1682350..1682814) 1 NC_012759.1 MG1655 equivalent: b1708; putative lipoprotein 1682814 nlpC 7952811 nlpC Escherichia coli BW2952 putative lipoprotein YP_002926719.1 1682350 R 595496 CDS YP_002926720.1 238900924 7955109 complement(1682892..1683641) 1 NC_012759.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1683641 btuD 7955109 btuD Escherichia coli BW2952 vitamin B12-transporter ATPase YP_002926720.1 1682892 R 595496 CDS YP_002926721.1 238900925 7956271 complement(1683641..1684192) 1 NC_012759.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase 1684192 btuE 7956271 btuE Escherichia coli BW2952 putative glutathione peroxidase YP_002926721.1 1683641 R 595496 CDS YP_002926722.1 238900926 7954925 complement(1684255..1685235) 1 NC_012759.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1685235 btuC 7954925 btuC Escherichia coli BW2952 vtamin B12-transporter permease YP_002926722.1 1684255 R 595496 CDS YP_002926723.1 238900927 7956272 complement(1685336..1685635) 1 NC_012759.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1685635 ihfA 7956272 ihfA Escherichia coli BW2952 integration host factor subunit alpha YP_002926723.1 1685336 R 595496 CDS YP_002926724.1 238900928 7954010 complement(1685640..1688027) 1 NC_012759.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1688027 pheT 7954010 pheT Escherichia coli BW2952 phenylalanyl-tRNA synthetase subunit beta YP_002926724.1 1685640 R 595496 CDS YP_002926725.1 238900929 7954510 complement(1688042..1689025) 1 NC_012759.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1689025 pheS 7954510 pheS Escherichia coli BW2952 phenylalanyl-tRNA synthetase subunit alpha YP_002926725.1 1688042 R 595496 CDS YP_002926727.1 238900931 7954511 complement(1689476..1689832) 1 NC_012759.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1689832 rplT 7954511 rplT Escherichia coli BW2952 50S ribosomal protein L20 YP_002926727.1 1689476 R 595496 CDS YP_002926728.1 238900932 7952348 complement(1689885..1690082) 1 NC_012759.1 MG1655 equivalent: b1717; 50S ribosomal protein L35 1690082 rpmI 7952348 rpmI Escherichia coli BW2952 50S ribosomal protein L35 YP_002926728.1 1689885 R 595496 CDS YP_002926729.1 238900933 7952363 complement(1690179..1690721) 1 NC_012759.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1690721 infC 7952363 infC Escherichia coli BW2952 translation initiation factor IF-3 YP_002926729.1 1690179 R 595496 CDS YP_002926730.1 238900934 7955789 complement(1690725..1692653) 1 NC_012759.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1692653 thrS 7955789 thrS Escherichia coli BW2952 threonyl-tRNA synthetase YP_002926730.1 1690725 R 595496 CDS YP_002926731.1 238900935 7956147 1695248..1695355 1 NC_012759.1 MG1655 equivalent: b4535; hypothetical protein 1695355 yniD 7956147 yniD Escherichia coli BW2952 hypothetical protein YP_002926731.1 1695248 D 595496 CDS YP_002926732.1 238900936 7955530 complement(1695408..1696166) 1 NC_012759.1 MG1655 equivalent: b1722; hypothetical protein 1696166 ydiY 7955530 ydiY Escherichia coli BW2952 hypothetical protein YP_002926732.1 1695408 R 595496 CDS YP_002926733.1 238900937 7952812 1696453..1697382 1 NC_012759.1 MG1655 equivalent: b1723; 6-phosphofructokinase 1697382 pfkB 7952812 pfkB Escherichia coli BW2952 6-phosphofructokinase YP_002926733.1 1696453 D 595496 CDS YP_002926734.1 238900938 7952378 1697483..1697773 1 NC_012759.1 MG1655 equivalent: b1724; hypothetical protein 1697773 ydiZ 7952378 ydiZ Escherichia coli BW2952 hypothetical protein YP_002926734.1 1697483 D 595496 CDS YP_002926735.1 238900939 7955477 1697879..1698739 1 NC_012759.1 MG1655 equivalent: b1725; putative phosphotransferase/kinase 1698739 yniA 7955477 yniA Escherichia coli BW2952 putative phosphotransferase/kinase YP_002926735.1 1697879 D 595496 CDS YP_002926736.1 238900940 7955321 complement(1698780..1699316) 1 NC_012759.1 MG1655 equivalent: b1726; putative inner membrane protein 1699316 yniB 7955321 yniB Escherichia coli BW2952 putative inner membrane protein YP_002926736.1 1698780 R 595496 CDS YP_002926737.1 238900941 7954996 1699463..1700131 1 NC_012759.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1700131 yniC 7954996 yniC Escherichia coli BW2952 2-deoxyglucose-6-phosphatase YP_002926737.1 1699463 D 595496 CDS YP_002926738.1 238900942 7954966 1700282..1700884 1 NC_012759.1 MG1655 equivalent: b1728; hypothetical protein 1700884 ydjM 7954966 ydjM Escherichia coli BW2952 hypothetical protein YP_002926738.1 1700282 D 595496 CDS YP_002926739.1 238900943 7955076 1701017..1702408 1 NC_012759.1 MG1655 equivalent: b1729; putative transporter 1702408 ydjN 7955076 ydjN Escherichia coli BW2952 putative transporter YP_002926739.1 1701017 D 595496 CDS YP_002926740.1 238900944 7955691 complement(1702412..1703227) 1 NC_012759.1 MG1655 equivalent: b1730; hypothetical protein 1703227 ydjO 7955691 ydjO Escherichia coli BW2952 hypothetical protein YP_002926740.1 1702412 R 595496 CDS YP_002926741.1 238900945 7955367 complement(1703504..1703746) 1 NC_012759.1 MG1655 equivalent: b1731; cell division modulator 1703746 cedA 7955367 cedA Escherichia coli BW2952 cell division modulator YP_002926741.1 1703504 R 595496 CDS YP_002926742.1 238900946 7952615 1703950..1706211 1 NC_012759.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1706211 katE 7952615 katE Escherichia coli BW2952 hydroperoxidase II YP_002926742.1 1703950 D 595496 CDS YP_002926743.1 238900947 7953958 complement(1706469..1707218) 1 NC_012759.1 MG1655 equivalent: b1733; hypothetical protein 1707218 chbG 7953958 chbG Escherichia coli BW2952 hypothetical protein YP_002926743.1 1706469 R 595496 CDS YP_002926744.1 238900948 7952813 complement(1707231..1708583) 1 NC_012759.1 MG1655 equivalent: b1734; cryptic phospho-beta-glucosidase, NAD(P)-binding 1708583 chbF 7952813 chbF Escherichia coli BW2952 cryptic phospho-beta-glucosidase, NAD(P)-binding YP_002926744.1 1707231 R 595496 CDS YP_002926745.1 238900949 7953172 complement(1708688..1709530) 1 NC_012759.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1709530 chbR 7953172 chbR Escherichia coli BW2952 DNA-binding transcriptional regulator ChbR YP_002926745.1 1708688 R 595496 CDS YP_002926746.1 238900950 7953406 complement(1709538..1709888) 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1709888 chbA 7953406 chbA Escherichia coli BW2952 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_002926746.1 1709538 R 595496 CDS YP_002926747.1 238900951 7954327 complement(1709939..1711297) 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1711297 chbC 7954327 chbC Escherichia coli BW2952 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_002926747.1 1709939 R 595496 CDS YP_002926748.1 238900952 7954329 complement(1711382..1711702) 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1711702 chbB 7954329 chbB Escherichia coli BW2952 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_002926748.1 1711382 R 595496 CDS YP_002926749.1 238900953 7954328 complement(1712001..1712339) 1 NC_012759.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1712339 osmE 7954328 osmE Escherichia coli BW2952 DNA-binding transcriptional activator OsmE YP_002926749.1 1712001 R 595496 CDS YP_002926750.1 238900954 7953366 1712541..1713368 1 NC_012759.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1713368 nadE 7953366 nadE Escherichia coli BW2952 NAD synthetase YP_002926750.1 1712541 D 595496 CDS YP_002926751.1 238900955 7954349 1713598..1714485 1 NC_012759.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1714485 cho 7954349 cho Escherichia coli BW2952 nucleotide excision repair endonuclease YP_002926751.1 1713598 D 595496 CDS YP_002926752.1 238900956 7953518 complement(1714445..1715020) 1 NC_012759.1 MG1655 equivalent: b1742; hypothetical protein 1715020 ves 7953518 ves Escherichia coli BW2952 hypothetical protein YP_002926752.1 1714445 R 595496 CDS YP_002926753.1 238900957 7952814 complement(1715223..1715708) 1 NC_012759.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1715708 spy 7952814 spy Escherichia coli BW2952 hypothetical protein YP_002926753.1 1715223 R 595496 CDS YP_002926754.1 238900958 7953530 complement(1716038..1717006) 1 NC_012759.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1717006 astE 7953530 astE Escherichia coli BW2952 succinylglutamate desuccinylase YP_002926754.1 1716038 R 595496 CDS YP_002926755.1 238900959 7956084 complement(1716999..1718342) 1 NC_012759.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1718342 astB 7956084 astB Escherichia coli BW2952 succinylarginine dihydrolase YP_002926755.1 1716999 R 595496 CDS YP_002926756.1 238900960 7956081 complement(1718339..1719817) 1 NC_012759.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1719817 astD 7956081 astD Escherichia coli BW2952 succinylglutamic semialdehyde dehydrogenase YP_002926756.1 1718339 R 595496 CDS YP_002926757.1 238900961 7956085 complement(1719814..1720848) 1 NC_012759.1 MG1655 equivalent: b1747; arginine succinyltransferase 1720848 astA 7956085 astA Escherichia coli BW2952 arginine succinyltransferase YP_002926757.1 1719814 R 595496 CDS YP_002926758.1 238900962 7952493 complement(1720845..1722065) 1 NC_012759.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1722065 astC 7952493 astC Escherichia coli BW2952 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_002926758.1 1720845 R 595496 CDS YP_002926759.1 238900963 7956086 1722511..1723317 1 NC_012759.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1723317 xthA 7956086 xthA Escherichia coli BW2952 exonuclease III YP_002926759.1 1722511 D 595496 CDS YP_002926760.1 238900964 7953540 1723484..1724194 1 NC_012759.1 MG1655 equivalent: b1750; putative inner membrane protein 1724194 ydjX 7953540 ydjX Escherichia coli BW2952 putative inner membrane protein YP_002926760.1 1723484 D 595496 CDS YP_002926761.1 238900965 7955045 1724199..1724876 1 NC_012759.1 MG1655 equivalent: b1751; hypothetical protein 1724876 ydjY 7955045 ydjY Escherichia coli BW2952 hypothetical protein YP_002926761.1 1724199 D 595496 CDS YP_002926762.1 238900966 7955478 1724891..1725598 1 NC_012759.1 MG1655 equivalent: b1752; hypothetical protein 1725598 ydjZ 7955478 ydjZ Escherichia coli BW2952 hypothetical protein YP_002926762.1 1724891 D 595496 CDS YP_002926763.1 238900967 7952710 1725598..1726146 1 NC_012759.1 MG1655 equivalent: b1753; hypothetical protein 1726146 ynjA 7952710 ynjA Escherichia coli BW2952 hypothetical protein YP_002926763.1 1725598 D 595496 CDS YP_002926764.1 238900968 7952976 1726156..1727322 1 NC_012759.1 MG1655 equivalent: b1754; putative ABC transporter solute-binding protein 1727322 ynjB 7952976 ynjB Escherichia coli BW2952 putative ABC transporter solute-binding protein YP_002926764.1 1726156 D 595496 CDS YP_002926765.1 238900969 7952977 1727295..1728830 1 NC_012759.1 MG1655 equivalent: b1755; fused transporter subunits of ABC superfamily: membrane components 1728830 ynjC 7952977 ynjC Escherichia coli BW2952 fused transporter subunits of ABC superfamily: membrane components YP_002926765.1 1727295 D 595496 CDS YP_002926766.1 238900970 7953748 1728830..1729483 1 NC_012759.1 MG1655 equivalent: b1756; putative transporter subunit: ATP-binding component of ABC superfamily 1729483 ynjD 7953748 ynjD Escherichia coli BW2952 putative transporter subunit: ATP-binding component of ABC superfamily YP_002926766.1 1728830 D 595496 CDS YP_002926767.1 238900971 7955723 1729550..1730857 1 NC_012759.1 MG1655 equivalent: b1757; putative thiosulfate sulfur transferase 1730857 ynjE 7955723 ynjE Escherichia coli BW2952 putative thiosulfate sulfur transferase YP_002926767.1 1729550 D 595496 CDS YP_002926768.1 238900972 7955623 complement(1730866..1731486) 1 NC_012759.1 MG1655 equivalent: b1758; putative phosphatidyl transferase, inner membrane protein 1731486 ynjF 7955623 ynjF Escherichia coli BW2952 putative phosphatidyl transferase, inner membrane protein YP_002926768.1 1730866 R 595496 CDS YP_002926769.1 238900973 7955314 1731573..1731980 1 NC_012759.1 MG1655 equivalent: b1759; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1731980 nudG 7955314 nudG Escherichia coli BW2952 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_002926769.1 1731573 D 595496 CDS YP_002926770.1 238900974 7955842 complement(1731946..1732218) 1 NC_012759.1 MG1655 equivalent: b1760; hypothetical protein 1732218 ynjH 7955842 ynjH Escherichia coli BW2952 hypothetical protein YP_002926770.1 1731946 R 595496 CDS YP_002926771.1 238900975 7955368 1732454..1733797 1 NC_012759.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1733797 gdhA 7955368 gdhA Escherichia coli BW2952 glutamate dehydrogenase YP_002926771.1 1732454 D 595496 CDS YP_002926772.1 238900976 7953820 complement(1733914..1734954) 1 NC_012759.1 MG1655 equivalent: b1762; hypothetical protein 1734954 ynjI 7953820 ynjI Escherichia coli BW2952 hypothetical protein YP_002926772.1 1733914 R 595496 CDS YP_002926773.1 238900977 7954997 complement(1735082..1737043) 1 NC_012759.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1737043 topB 7954997 topB Escherichia coli BW2952 DNA topoisomerase III YP_002926773.1 1735082 R 595496 CDS YP_002926774.1 238900978 7953334 complement(1737048..1738091) 1 NC_012759.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1738091 selD 7953334 selD Escherichia coli BW2952 selenophosphate synthetase YP_002926774.1 1737048 R 595496 CDS YP_002926775.1 238900979 7956009 complement(1738208..1738759) 1 NC_012759.1 MG1655 equivalent: b1765; hypothetical protein 1738759 ydjA 7956009 ydjA Escherichia coli BW2952 hypothetical protein YP_002926775.1 1738208 R 595496 CDS YP_002926776.1 238900980 7955228 1738920..1740776 1 NC_012759.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1740776 sppA 7955228 sppA Escherichia coli BW2952 protease 4 YP_002926776.1 1738920 D 595496 CDS YP_002926777.1 238900981 7955778 1740943..1741959 1 NC_012759.1 converts asparagine to aspartate and ammonia; asparaginase 1741959 ansA 7955778 ansA Escherichia coli BW2952 asparaginase YP_002926777.1 1740943 D 595496 CDS YP_002926778.1 238900982 7953202 1741970..1742611 1 NC_012759.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1742611 pncA 7953202 pncA Escherichia coli BW2952 nicotinamidase/pyrazinamidase YP_002926778.1 1741970 D 595496 CDS YP_002926779.1 238900983 7954382 complement(1742704..1744062) 1 NC_012759.1 MG1655 equivalent: b1769; putative transporter 1744062 ydjE 7954382 ydjE Escherichia coli BW2952 putative transporter YP_002926779.1 1742704 R 595496 CDS YP_002926780.1 238900984 7955657 complement(1744179..1744937) 1 NC_012759.1 MG1655 equivalent: b1770; putative DNA-binding transcriptional regulator 1744937 ydjF 7955657 ydjF Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926780.1 1744179 R 595496 CDS YP_002926781.1 238900985 7954761 complement(1745074..1746054) 1 NC_012759.1 MG1655 equivalent: b1771; putative oxidoreductase 1746054 ydjG 7954761 ydjG Escherichia coli BW2952 putative oxidoreductase YP_002926781.1 1745074 R 595496 CDS YP_002926782.1 238900986 7955229 complement(1746064..1747011) 1 NC_012759.1 MG1655 equivalent: b1772; putative kinase 1747011 ydjH 7955229 ydjH Escherichia coli BW2952 putative kinase YP_002926782.1 1746064 R 595496 CDS YP_002926783.1 238900987 7955092 complement(1747016..1747852) 1 NC_012759.1 MG1655 equivalent: b1773; putative aldolase 1747852 ydjI 7955092 ydjI Escherichia coli BW2952 putative aldolase YP_002926783.1 1747016 R 595496 CDS YP_002926784.1 238900988 7954629 complement(1747873..1748916) 1 NC_012759.1 MG1655 equivalent: b1774; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1748916 ydjJ 7954629 ydjJ Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002926784.1 1747873 R 595496 CDS YP_002926785.1 238900989 7955259 complement(1748933..1750312) 1 NC_012759.1 MG1655 equivalent: b1775; putative transporter 1750312 ydjK 7955259 ydjK Escherichia coli BW2952 putative transporter YP_002926785.1 1748933 R 595496 CDS YP_002926786.1 238900990 7955658 complement(1750339..1751415) 1 NC_012759.1 MG1655 equivalent: b1776; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1751415 ydjL 7955658 ydjL Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002926786.1 1750339 R 595496 CDS YP_002926787.1 238900991 7955260 complement(1751785..1752057) 1 NC_012759.1 MG1655 equivalent: b1777; hypothetical protein 1752057 yeaC 7955260 yeaC Escherichia coli BW2952 hypothetical protein YP_002926787.1 1751785 R 595496 CDS YP_002926788.1 238900992 7952815 complement(1752099..1752512) 1 NC_012759.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1752512 msrB 7952815 msrB Escherichia coli BW2952 methionine sulfoxide reductase B YP_002926788.1 1752099 R 595496 CDS YP_002926789.1 238900993 7954246 1752854..1753849 1 NC_012759.1 MG1655 equivalent: b1779; glyceraldehyde-3-phosphate dehydrogenase 1753849 gapA 7954246 gapA Escherichia coli BW2952 glyceraldehyde-3-phosphate dehydrogenase YP_002926789.1 1752854 D 595496 CDS YP_002926790.1 238900994 7953842 1753933..1754817 1 NC_012759.1 MG1655 equivalent: b1780; hypothetical protein 1754817 yeaD 7953842 yeaD Escherichia coli BW2952 hypothetical protein YP_002926790.1 1753933 D 595496 CDS YP_002926791.1 238900995 7952978 complement(1754865..1755719) 1 NC_012759.1 MG1655 equivalent: b1781; putative oxidoreductase 1755719 yeaE 7952978 yeaE Escherichia coli BW2952 putative oxidoreductase YP_002926791.1 1754865 R 595496 CDS YP_002926792.1 238900996 7955230 complement(1755809..1756555) 1 NC_012759.1 MG1655 equivalent: b1782; scaffolding protein for murein synthesizing machinery 1756555 mipA 7955230 mipA Escherichia coli BW2952 scaffolding protein for murein synthesizing machinery YP_002926792.1 1755809 R 595496 CDS YP_002926793.1 238900997 7956002 1756991..1758925 1 NC_012759.1 MG1655 equivalent: b1783; hypothetical protein 1758925 yeaG 7956002 yeaG Escherichia coli BW2952 hypothetical protein YP_002926793.1 1756991 D 595496 CDS YP_002926794.1 238900998 7953091 1759038..1760321 1 NC_012759.1 MG1655 equivalent: b1784; hypothetical protein 1760321 yeaH 7953091 yeaH Escherichia coli BW2952 hypothetical protein YP_002926794.1 1759038 D 595496 CDS YP_002926795.1 238900999 7952979 1760468..1761943 1 NC_012759.1 MG1655 equivalent: b1785; putative diguanylate cyclase 1761943 yeaI 7952979 yeaI Escherichia coli BW2952 putative diguanylate cyclase YP_002926795.1 1760468 D 595496 CDS YP_002926796.1 238901000 7954729 1762124..1763614 1 NC_012759.1 MG1655 equivalent: b1786; putative diguanylate cyclase 1763614 yeaJ 7954729 yeaJ Escherichia coli BW2952 putative diguanylate cyclase YP_002926796.1 1762124 D 595496 CDS YP_002926797.1 238901001 7954730 1763657..1764160 1 NC_012759.1 MG1655 equivalent: b1787; hypothetical protein 1764160 yeaK 7954730 yeaK Escherichia coli BW2952 hypothetical protein YP_002926797.1 1763657 D 595496 CDS YP_002926798.1 238901002 7952980 complement(1764161..1764265) 1 NC_012759.1 MG1655 equivalent: b1788; hypothetical protein 1764265 yoaI 7952980 yoaI Escherichia coli BW2952 hypothetical protein YP_002926798.1 1764161 R 595496 CDS YP_002926799.1 238901003 7955369 1764435..1764881 1 NC_012759.1 MG1655 equivalent: b1789; hypothetical protein 1764881 yeaL 7955369 yeaL Escherichia coli BW2952 hypothetical protein YP_002926799.1 1764435 D 595496 CDS YP_002926800.1 238901004 7952711 complement(1764838..1765659) 1 NC_012759.1 MG1655 equivalent: b1790; putative DNA-binding transcriptional regulator 1765659 yeaM 7952711 yeaM Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926800.1 1764838 R 595496 CDS YP_002926801.1 238901005 7954762 1765756..1766937 1 NC_012759.1 MG1655 equivalent: b1791; putative transporter 1766937 yeaN 7954762 yeaN Escherichia coli BW2952 putative transporter YP_002926801.1 1765756 D 595496 CDS YP_002926802.1 238901006 7955692 1766992..1767339 1 NC_012759.1 MG1655 equivalent: b1792; hypothetical protein 1767339 yeaO 7955692 yeaO Escherichia coli BW2952 hypothetical protein YP_002926802.1 1766992 D 595496 CDS YP_002926803.1 238901007 7952981 complement(1767361..1767615) 1 NC_012759.1 MG1655 equivalent: b1793; hypothetical protein 1767615 yoaF 7952981 yoaF Escherichia coli BW2952 hypothetical protein YP_002926803.1 1767361 R 595496 CDS YP_002926804.1 238901008 7952749 1767798..1768823 1 NC_012759.1 MG1655 equivalent: b1794; putative diguanylate cyclase 1768823 yeaP 7952749 yeaP Escherichia coli BW2952 putative diguanylate cyclase YP_002926804.1 1767798 D 595496 CDS YP_002926805.1 238901009 7954731 complement(1769090..1769338) 1 NC_012759.1 MG1655 equivalent: b1795; hypothetical protein 1769338 yeaQ 7954731 yeaQ Escherichia coli BW2952 hypothetical protein YP_002926805.1 1769090 R 595496 CDS YP_002926806.1 238901010 7952672 complement(1769486..1769668) 1 NC_012759.1 MG1655 equivalent: b1796; hypothetical protein 1769668 yoaG 7952672 yoaG Escherichia coli BW2952 hypothetical protein YP_002926806.1 1769486 R 595496 CDS YP_002926807.1 238901011 7955370 complement(1769672..1770031) 1 NC_012759.1 MG1655 equivalent: b1797; hypothetical protein 1770031 yeaR 7955370 yeaR Escherichia coli BW2952 hypothetical protein YP_002926807.1 1769672 R 595496 CDS YP_002926808.1 238901012 7952816 complement(1770204..1770842) 1 NC_012759.1 MG1655 equivalent: b1798; leucine export protein LeuE 1770842 leuE 7952816 leuE Escherichia coli BW2952 leucine export protein LeuE YP_002926808.1 1770204 R 595496 CDS YP_002926809.1 238901013 7954373 complement(1770969..1771892) 1 NC_012759.1 MG1655 equivalent: b1799; putative DNA-binding transcriptional regulator 1771892 yeaT 7954373 yeaT Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926809.1 1770969 R 595496 CDS YP_002926810.1 238901014 7954763 1771995..1773080 1 NC_012759.1 MG1655 equivalent: b1800; putative dehydrogenase 1773080 yeaU 7954763 yeaU Escherichia coli BW2952 putative dehydrogenase YP_002926810.1 1771995 D 595496 CDS YP_002926811.1 238901015 7954716 1773271..1774716 1 NC_012759.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; putative transporter 1774716 yeaV 7954716 yeaV Escherichia coli BW2952 putative transporter YP_002926811.1 1773271 D 595496 CDS YP_002926812.1 238901016 7955693 1774748..1775872 1 NC_012759.1 MG1655 equivalent: b1802; putative 2Fe-2S cluster-containing protein 1775872 yeaW 7955693 yeaW Escherichia coli BW2952 putative 2Fe-2S cluster-containing protein YP_002926812.1 1774748 D 595496 CDS YP_002926813.1 238901017 7954585 1775928..1776893 1 NC_012759.1 MG1655 equivalent: b1803; putative oxidoreductase 1776893 yeaX 7954585 yeaX Escherichia coli BW2952 putative oxidoreductase YP_002926813.1 1775928 D 595496 CDS YP_002926814.1 238901018 7955233 complement(1776947..1778074) 1 NC_012759.1 MG1655 equivalent: b1804; ribonuclease D 1778074 rnd 7955233 rnd Escherichia coli BW2952 ribonuclease D YP_002926814.1 1776947 R 595496 CDS YP_002926815.1 238901019 7955956 complement(1778144..1779829) 1 NC_012759.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1779829 fadD 7955956 fadD Escherichia coli BW2952 long-chain-fatty-acid--CoA ligase YP_002926815.1 1778144 R 595496 CDS YP_002926816.1 238901020 7952416 complement(1780034..1780615) 1 NC_012759.1 MG1655 equivalent: b1806; putative lipoprotein 1780615 yeaY 7952416 yeaY Escherichia coli BW2952 putative lipoprotein YP_002926816.1 1780034 R 595496 CDS YP_002926817.1 238901021 7955110 complement(1780655..1781350) 1 NC_012759.1 MG1655 equivalent: b1807; putative peptidase 1781350 yeaZ 7955110 yeaZ Escherichia coli BW2952 putative peptidase YP_002926817.1 1780655 R 595496 CDS YP_002926818.1 238901022 7955272 complement(1781408..1783318) 1 NC_012759.1 MG1655 equivalent: b1808; hypothetical protein 1783318 yoaA 7955272 yoaA Escherichia coli BW2952 hypothetical protein YP_002926818.1 1781408 R 595496 CDS YP_002926819.1 238901023 7953084 1783450..1783794 1 NC_012759.1 MG1655 equivalent: b1809; hypothetical protein 1783794 yoaB 7953084 yoaB Escherichia coli BW2952 hypothetical protein YP_002926819.1 1783450 D 595496 CDS YP_002926820.1 238901024 7952982 1784156..1784515 1 NC_012759.1 MG1655 equivalent: b1810; hypothetical protein 1784515 yoaC 7952982 yoaC Escherichia coli BW2952 hypothetical protein YP_002926820.1 1784156 D 595496 CDS YP_002926821.1 238901025 7955479 complement(1784635..1784814) 1 NC_012759.1 MG1655 equivalent: b1811; hypothetical protein 1784814 yoaH 7955479 yoaH Escherichia coli BW2952 hypothetical protein YP_002926821.1 1784635 R 595496 CDS YP_002926822.1 238901026 7952817 1784888..1786249 1 NC_012759.1 MG1655 equivalent: b1812; aminodeoxychorismate synthase subunit I 1786249 pabB 7952817 pabB Escherichia coli BW2952 aminodeoxychorismate synthase subunit I YP_002926822.1 1784888 D 595496 CDS YP_002926823.1 238901027 7952465 1786253..1786831 1 NC_012759.1 MG1655 equivalent: b1813; hypothetical protein 1786831 nudL 7952465 nudL Escherichia coli BW2952 hypothetical protein YP_002926823.1 1786253 D 595496 CDS YP_002926824.1 238901028 7955190 1787015..1788379 1 NC_012759.1 MG1655 equivalent: b1814; L-serine deaminase I 1788379 sdaA 7955190 sdaA Escherichia coli BW2952 L-serine deaminase I YP_002926824.1 1787015 D 595496 CDS YP_002926825.1 238901029 7954170 1788510..1790108 1 NC_012759.1 MG1655 equivalent: b1815; putative phosphodiesterase 1790108 yoaD 7954170 yoaD Escherichia coli BW2952 putative phosphodiesterase YP_002926825.1 1788510 D 595496 CDS YP_002926826.1 238901030 7955315 complement(1790112..1791668) 1 NC_012759.1 MG1655 equivalent: b1816; hypothetical protein 1791668 yoaE 7955315 yoaE Escherichia coli BW2952 hypothetical protein YP_002926826.1 1790112 R 595496 CDS YP_002926827.1 238901031 7953713 1792131..1793102 1 NC_012759.1 MG1655 equivalent: b1817; fused mannose-specific PTS enzymes: IIA component/IIB component 1793102 manX 7953713 manX Escherichia coli BW2952 fused mannose-specific PTS enzymes: IIA component/IIB component YP_002926827.1 1792131 D 595496 CDS YP_002926828.1 238901032 7953699 1793165..1793965 1 NC_012759.1 MG1655 equivalent: b1818; mannose-specific enzyme IIC component of PTS 1793965 manY 7953699 manY Escherichia coli BW2952 mannose-specific enzyme IIC component of PTS YP_002926828.1 1793165 D 595496 CDS YP_002926829.1 238901033 7954216 1793969..1794829 1 NC_012759.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1794829 manZ 7954216 manZ Escherichia coli BW2952 PTS system mannose-specific transporter subunit IID YP_002926829.1 1793969 D 595496 CDS YP_002926830.1 238901034 7954217 1794884..1795342 1 NC_012759.1 MG1655 equivalent: b1820; hypothetical protein 1795342 yobD 7954217 yobD Escherichia coli BW2952 hypothetical protein YP_002926830.1 1794884 D 595496 CDS YP_002926831.1 238901035 7952712 1795771..1796337 1 NC_012759.1 membrane protein YebN; hypothetical protein 1796337 yebN 7952712 yebN Escherichia coli BW2952 hypothetical protein YP_002926831.1 1795771 D 595496 CDS YP_002926832.1 238901036 7952713 complement(1796334..1797143) 1 NC_012759.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 1797143 rrmA 7952713 rrmA Escherichia coli BW2952 23S rRNA methyltransferase A YP_002926832.1 1796334 R 595496 CDS YP_002926833.1 238901037 7952244 complement(1797309..1797518) 1 NC_012759.1 MG1655 equivalent: b1823; cold shock-like protein CspC 1797518 cspC 7952244 cspC Escherichia coli BW2952 cold shock-like protein CspC YP_002926833.1 1797309 R 595496 CDS YP_002926834.1 238901038 7956070 complement(1797531..1797674) 1 NC_012759.1 MG1655 equivalent: b1824; hypothetical protein 1797674 yobF 7956070 yobF Escherichia coli BW2952 hypothetical protein YP_002926834.1 1797531 R 595496 CDS YP_002926835.1 238901039 7955371 complement(1798344..1798631) 1 NC_012759.1 MG1655 equivalent: b1825; hypothetical protein 1798631 yebO 7955371 yebO Escherichia coli BW2952 hypothetical protein YP_002926835.1 1798344 R 595496 CDS YP_002926836.1 238901040 7955372 complement(1798706..1798849) 1 NC_012759.1 MG1655 equivalent: b1826; hypothetical protein 1798849 mgrB 7955372 mgrB Escherichia coli BW2952 hypothetical protein YP_002926836.1 1798706 R 595496 CDS YP_002926837.1 238901041 7955373 1799008..1799247 1 NC_012759.1 MG1655 equivalent: b4536; hypothetical protein 1799247 yobH 7955373 yobH Escherichia coli BW2952 hypothetical protein YP_002926837.1 1799008 D 595496 CDS YP_002926838.1 238901042 7955531 complement(1799391..1800182) 1 NC_012759.1 MG1655 equivalent: b1827; putative DNA-binding transcriptional regulator 1800182 kdgR 7955531 kdgR Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002926838.1 1799391 R 595496 CDS YP_002926839.1 238901043 7954764 1800359..1801732 1 NC_012759.1 MG1655 equivalent: b1828; putative transporter 1801732 yebQ 7954764 yebQ Escherichia coli BW2952 putative transporter YP_002926839.1 1800359 D 595496 CDS YP_002926840.1 238901044 7955694 complement(1801778..1802659) 1 NC_012759.1 putative metalloprotease; heat shock protein HtpX 1802659 htpX 7955694 htpX Escherichia coli BW2952 heat shock protein HtpX YP_002926840.1 1801778 R 595496 CDS YP_002926841.1 238901045 7954836 complement(1802851..1804899) 1 NC_012759.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1804899 prc 7954836 prc Escherichia coli BW2952 carboxy-terminal protease YP_002926841.1 1802851 R 595496 CDS YP_002926842.1 238901046 7952607 complement(1804919..1805617) 1 NC_012759.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 1805617 proQ 7952607 proQ Escherichia coli BW2952 putative solute/DNA competence effector YP_002926842.1 1804919 R 595496 CDS YP_002926843.1 238901047 7955601 complement(1805714..1806211) 1 NC_012759.1 MG1655 equivalent: b1832; free methionine-(R)-sulfoxide reductase 1806211 yebR 7955601 yebR Escherichia coli BW2952 free methionine-(R)-sulfoxide reductase YP_002926843.1 1805714 R 595496 CDS YP_002926844.1 238901048 7953632 1806341..1807624 1 NC_012759.1 MG1655 equivalent: b1833; hypothetical protein 1807624 yebS 7953632 yebS Escherichia coli BW2952 hypothetical protein YP_002926844.1 1806341 D 595496 CDS YP_002926845.1 238901049 7952714 1807593..1810226 1 NC_012759.1 MG1655 equivalent: b1834; hypothetical protein 1810226 yebT 7952714 yebT Escherichia coli BW2952 hypothetical protein YP_002926845.1 1807593 D 595496 CDS YP_002926846.1 238901050 7952983 1810306..1811745 1 NC_012759.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1811745 yebU 7952983 yebU Escherichia coli BW2952 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_002926846.1 1810306 D 595496 CDS YP_002926847.1 238901051 7955158 1811863..1812099 1 NC_012759.1 MG1655 equivalent: b1836; hypothetical protein 1812099 yebV 7955158 yebV Escherichia coli BW2952 hypothetical protein YP_002926847.1 1811863 D 595496 CDS YP_002926848.1 238901052 7955480 1812204..1812395 1 NC_012759.1 MG1655 equivalent: b1837; hypothetical protein 1812395 yebW 7955480 yebW Escherichia coli BW2952 hypothetical protein YP_002926848.1 1812204 D 595496 CDS YP_002926849.1 238901053 7955481 complement(1812396..1813052) 1 NC_012759.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1813052 pphA 7955481 pphA Escherichia coli BW2952 serine/threonine protein phosphatase 1 YP_002926849.1 1812396 R 595496 CDS YP_002926850.1 238901054 7952084 complement(1813448..1813789) 1 NC_012759.1 MG1655 equivalent: b1839; hypothetical protein 1813789 yebY 7952084 yebY Escherichia coli BW2952 hypothetical protein YP_002926850.1 1813448 R 595496 CDS YP_002926851.1 238901055 7955374 complement(1813802..1814674) 1 NC_012759.1 MG1655 equivalent: b1840; putative inner membrane protein 1814674 yebZ 7955374 yebZ Escherichia coli BW2952 putative inner membrane protein YP_002926851.1 1813802 R 595496 CDS YP_002926852.1 238901056 7954998 complement(1814678..1815052) 1 NC_012759.1 MG1655 equivalent: b1841; hypothetical protein 1815052 yobA 7954998 yobA Escherichia coli BW2952 hypothetical protein YP_002926852.1 1814678 R 595496 CDS YP_002926853.1 238901057 7952818 1815191..1815421 1 NC_012759.1 MG1655 equivalent: b1842; DNA polymerase III subunit theta 1815421 holE 7952818 holE Escherichia coli BW2952 DNA polymerase III subunit theta YP_002926853.1 1815191 D 595496 CDS YP_002926854.1 238901058 7953325 1815523..1816179 1 NC_012759.1 MG1655 equivalent: b1843; hypothetical protein 1816179 yobB 7953325 yobB Escherichia coli BW2952 hypothetical protein YP_002926854.1 1815523 D 595496 CDS YP_002926855.1 238901059 7952984 1816203..1816865 1 NC_012759.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1816865 exoX 7952984 exoX Escherichia coli BW2952 exodeoxyribonuclease X YP_002926855.1 1816203 D 595496 CDS YP_002926856.1 238901060 7953304 complement(1816862..1818922) 1 NC_012759.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1818922 ptrB 7953304 ptrB Escherichia coli BW2952 protease 2 YP_002926856.1 1816862 R 595496 CDS YP_002926857.1 238901061 7955775 complement(1819131..1819790) 1 NC_012759.1 MG1655 equivalent: b1846; hypothetical protein 1819790 yebE 7955775 yebE Escherichia coli BW2952 hypothetical protein YP_002926857.1 1819131 R 595496 CDS YP_002926858.1 238901062 7952819 complement(1820117..1820473) 1 NC_012759.1 secreted protein; unknown function; hypothetical protein 1820473 yebF 7952819 yebF Escherichia coli BW2952 hypothetical protein YP_002926858.1 1820117 R 595496 CDS YP_002926859.1 238901063 7955375 complement(1820540..1820830) 1 NC_012759.1 MG1655 equivalent: b1848; DNA damage-inducible protein YebG 1820830 yebG 7955375 yebG Escherichia coli BW2952 DNA damage-inducible protein YebG YP_002926859.1 1820540 R 595496 CDS YP_002926860.1 238901064 7953075 1820964..1822142 1 NC_012759.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1822142 purT 7953075 purT Escherichia coli BW2952 phosphoribosylglycinamide formyltransferase 2 YP_002926860.1 1820964 D 595496 CDS YP_002926861.1 238901065 7954552 complement(1822198..1822839) 1 NC_012759.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1822839 eda 7954552 eda Escherichia coli BW2952 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002926861.1 1822198 R 595496 CDS YP_002926862.1 238901066 7954316 complement(1822876..1824687) 1 NC_012759.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1824687 edd 7954316 edd Escherichia coli BW2952 phosphogluconate dehydratase YP_002926862.1 1822876 R 595496 CDS YP_002926863.1 238901067 7952379 complement(1824922..1826397) 1 NC_012759.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1826397 zwf 7952379 zwf Escherichia coli BW2952 glucose-6-phosphate 1-dehydrogenase YP_002926863.1 1824922 R 595496 CDS YP_002926864.1 238901068 7953809 1826735..1827604 1 NC_012759.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1827604 yebK 7953809 yebK Escherichia coli BW2952 DNA-binding transcriptional regulator HexR YP_002926864.1 1826735 D 595496 CDS YP_002926865.1 238901069 7954803 1827732..1829174 1 NC_012759.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1829174 pykA 7954803 pykA Escherichia coli BW2952 pyruvate kinase YP_002926865.1 1827732 D 595496 CDS YP_002926866.1 238901070 7955853 complement(1829305..1830276) 1 NC_012759.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1830276 lpxM 7955853 lpxM Escherichia coli BW2952 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002926866.1 1829305 R 595496 CDS YP_002926867.1 238901071 7954325 complement(1830396..1831718) 1 NC_012759.1 MG1655 equivalent: b1856; hypothetical protein 1831718 yebA 7954325 yebA Escherichia coli BW2952 hypothetical protein YP_002926867.1 1830396 R 595496 CDS YP_002926868.1 238901072 7955273 complement(1831734..1832666) 1 NC_012759.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1832666 znuA 7955273 znuA Escherichia coli BW2952 high-affinity zinc transporter periplasmic protein YP_002926868.1 1831734 R 595496 CDS YP_002926869.1 238901073 7956288 1832745..1833500 1 NC_012759.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1833500 znuC 7956288 znuC Escherichia coli BW2952 high-affinity zinc transporter ATPase YP_002926869.1 1832745 D 595496 CDS YP_002926870.1 238901074 7956286 1833497..1834282 1 NC_012759.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1834282 znuB 7956286 znuB Escherichia coli BW2952 high-affinity zinc transporter membrane protein YP_002926870.1 1833497 D 595496 CDS YP_002926871.1 238901075 7956287 complement(1834429..1835439) 1 NC_012759.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1835439 ruvB 7956287 ruvB Escherichia coli BW2952 Holliday junction DNA helicase RuvB YP_002926871.1 1834429 R 595496 CDS YP_002926872.1 238901076 7952532 complement(1835448..1836059) 1 NC_012759.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1836059 ruvA 7952532 ruvA Escherichia coli BW2952 Holliday junction DNA helicase RuvA YP_002926872.1 1835448 R 595496 CDS YP_002926873.1 238901077 7952658 1836334..1836936 1 NC_012759.1 MG1655 equivalent: b1862; hypothetical protein 1836936 yebB 7952658 yebB Escherichia coli BW2952 hypothetical protein YP_002926873.1 1836334 D 595496 CDS YP_002926874.1 238901078 7955482 complement(1836938..1837459) 1 NC_012759.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1837459 ruvC 7955482 ruvC Escherichia coli BW2952 Holliday junction resolvase YP_002926874.1 1836938 R 595496 CDS YP_002926875.1 238901079 7952657 complement(1837494..1838234) 1 NC_012759.1 MG1655 equivalent: b1864; hypothetical protein 1838234 yebC 7952657 yebC Escherichia coli BW2952 hypothetical protein YP_002926875.1 1837494 R 595496 CDS YP_002926876.1 238901080 7952820 complement(1838263..1838715) 1 NC_012759.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1838715 ntpA 7952820 ntpA Escherichia coli BW2952 dATP pyrophosphohydrolase YP_002926876.1 1838263 R 595496 CDS YP_002926877.1 238901081 7953228 complement(1838833..1840605) 1 NC_012759.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1840605 aspS 7953228 aspS Escherichia coli BW2952 aspartyl-tRNA synthetase YP_002926877.1 1838833 R 595496 CDS YP_002926878.1 238901082 7952517 1840915..1841481 1 NC_012759.1 MG1655 equivalent: b1867; hypothetical protein 1841481 yecD 7952517 yecD Escherichia coli BW2952 hypothetical protein YP_002926878.1 1840915 D 595496 CDS YP_002926879.1 238901083 7954967 1841478..1842296 1 NC_012759.1 MG1655 equivalent: b1868; hypothetical protein 1842296 yecE 7954967 yecE Escherichia coli BW2952 hypothetical protein YP_002926879.1 1841478 D 595496 CDS YP_002926880.1 238901084 7952985 1842349..1842744 1 NC_012759.1 MG1655 equivalent: b1869; putative inner membrane protein 1842744 yecN 7952985 yecN Escherichia coli BW2952 putative inner membrane protein YP_002926880.1 1842349 D 595496 CDS YP_002926881.1 238901085 7955046 1842785..1843528 1 NC_012759.1 MG1655 equivalent: b1870; putative methyltransferase 1843528 cmoA 7955046 cmoA Escherichia coli BW2952 putative methyltransferase YP_002926881.1 1842785 D 595496 CDS YP_002926882.1 238901086 7955159 1843525..1844496 1 NC_012759.1 MG1655 equivalent: b1871; putative S-adenosyl-L-methionine-dependent methyltransferase 1844496 cmoB 7955159 cmoB Escherichia coli BW2952 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002926882.1 1843525 D 595496 CDS YP_002926883.1 238901087 7955580 complement(1844661..1847090) 1 NC_012759.1 MG1655 equivalent: b1872; trimethylamine N-oxide reductase system III, catalytic subunit 1847090 torZ 7955580 torZ Escherichia coli BW2952 trimethylamine N-oxide reductase system III, catalytic subunit YP_002926883.1 1844661 R 595496 CDS YP_002926884.1 238901088 7956192 complement(1847115..1848215) 1 NC_012759.1 MG1655 equivalent: b1873; TMAO reductase III (TorYZ), cytochrome c-type subunit 1848215 torY 7956192 torY Escherichia coli BW2952 TMAO reductase III (TorYZ), cytochrome c-type subunit YP_002926884.1 1847115 R 595496 CDS YP_002926885.1 238901089 7956152 complement(1848603..1849349) 1 NC_012759.1 MG1655 equivalent: b1874; copper homeostasis protein CutC 1849349 cutC 7956152 cutC Escherichia coli BW2952 copper homeostasis protein CutC YP_002926885.1 1848603 R 595496 CDS YP_002926886.1 238901090 7953096 complement(1849363..1849929) 1 NC_012759.1 MG1655 equivalent: b1875; hypothetical protein 1849929 yecM 7953096 yecM Escherichia coli BW2952 hypothetical protein YP_002926886.1 1849363 R 595496 CDS YP_002926887.1 238901091 7955146 1850145..1851878 1 NC_012759.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1851878 argS 7955146 argS Escherichia coli BW2952 arginyl-tRNA synthetase YP_002926887.1 1850145 D 595496 CDS YP_002926888.1 238901092 7952503 1852055..1852543 1 NC_012759.1 MG1655 equivalent: b1877; hypothetical protein 1852543 yecT 7952503 yecT Escherichia coli BW2952 hypothetical protein YP_002926888.1 1852055 D 595496 CDS YP_002926889.1 238901093 7955483 complement(1852663..1853055) 1 NC_012759.1 MG1655 equivalent: b1878; hypothetical protein 1853055 flhE 7955483 flhE Escherichia coli BW2952 hypothetical protein YP_002926889.1 1852663 R 595496 CDS YP_002926890.1 238901094 7952821 complement(1853055..1855133) 1 NC_012759.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1855133 flhA 7952821 flhA Escherichia coli BW2952 flagellar biosynthesis protein FlhA YP_002926890.1 1853055 R 595496 CDS YP_002926891.1 238901095 7954904 complement(1855126..1856274) 1 NC_012759.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1856274 flhB 7954904 flhB Escherichia coli BW2952 flagellar biosynthesis protein FlhB YP_002926891.1 1855126 R 595496 CDS YP_002926892.1 238901096 7954905 complement(1856476..1857120) 1 NC_012759.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1857120 cheZ 7954905 cheZ Escherichia coli BW2952 chemotaxis regulator CheZ YP_002926892.1 1856476 R 595496 CDS YP_002926893.1 238901097 7952632 complement(1857131..1857520) 1 NC_012759.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1857520 cheY 7952632 cheY Escherichia coli BW2952 chemotaxis regulatory protein CheY YP_002926893.1 1857131 R 595496 CDS YP_002926894.1 238901098 7952631 complement(1857535..1858584) 1 NC_012759.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1858584 cheB 7952631 cheB Escherichia coli BW2952 chemotaxis-specific methylesterase YP_002926894.1 1857535 R 595496 CDS YP_002926895.1 238901099 7953662 complement(1858587..1859447) 1 NC_012759.1 methylates the MCP; chemotaxis methyltransferase CheR 1859447 cheR 7953662 cheR Escherichia coli BW2952 chemotaxis methyltransferase CheR YP_002926895.1 1858587 R 595496 CDS YP_002926896.1 238901100 7952633 complement(1859466..1861067) 1 NC_012759.1 mediates taxis toward dipeptides; methyl-accepting protein IV 1861067 tap 7952633 tap Escherichia coli BW2952 methyl-accepting protein IV YP_002926896.1 1859466 R 595496 CDS YP_002926897.1 238901101 7954251 complement(1861113..1862774) 1 NC_012759.1 MG1655 equivalent: b1886; methyl-accepting chemotaxis protein II 1862774 tar 7954251 tar Escherichia coli BW2952 methyl-accepting chemotaxis protein II YP_002926897.1 1861113 R 595496 CDS YP_002926898.1 238901102 7954249 complement(1862919..1863422) 1 NC_012759.1 MG1655 equivalent: b1887; purine-binding chemotaxis protein 1863422 cheW 7954249 cheW Escherichia coli BW2952 purine-binding chemotaxis protein YP_002926898.1 1862919 R 595496 CDS YP_002926899.1 238901103 7955824 complement(1863443..1865407) 1 NC_012759.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1865407 cheA 7955824 cheA Escherichia coli BW2952 chemotaxis protein CheA YP_002926899.1 1863443 R 595496 CDS YP_002926900.1 238901104 7953661 complement(1865412..1866338) 1 NC_012759.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1866338 motB 7953661 motB Escherichia coli BW2952 flagellar motor protein MotB YP_002926900.1 1865412 R 595496 CDS YP_002926901.1 238901105 7955808 complement(1866335..1867222) 1 NC_012759.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1867222 motA 7955808 motA Escherichia coli BW2952 flagellar motor protein MotA YP_002926901.1 1866335 R 595496 CDS YP_002926902.1 238901106 7955816 complement(1867349..1867927) 1 NC_012759.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1867927 flhC 7955816 flhC Escherichia coli BW2952 transcriptional activator FlhC YP_002926902.1 1867349 R 595496 CDS YP_002926903.1 238901107 7952208 complement(1868725..1869741) 1 NC_012759.1 Transposase insH for insertion sequence element IS5 1869741 7952208 BWG_1707 Escherichia coli BW2952 Transposase insH for insertion sequence element IS5 YP_002926903.1 1868725 R 595496 CDS YP_002926904.1 238901108 7956185 1870260..1870688 1 NC_012759.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1870688 uspC 7956185 uspC Escherichia coli BW2952 universal stress protein UspC YP_002926904.1 1870260 D 595496 CDS YP_002926905.1 238901109 7956254 complement(1870695..1872119) 1 NC_012759.1 MG1655 equivalent: b1896; trehalose-6-phosphate synthase 1872119 otsA 7956254 otsA Escherichia coli BW2952 trehalose-6-phosphate synthase YP_002926905.1 1870695 R 595496 CDS YP_002926906.1 238901110 7956189 complement(1872094..1872894) 1 NC_012759.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1872894 otsB 7956189 otsB Escherichia coli BW2952 trehalose-6-phosphate phosphatase YP_002926906.1 1872094 R 595496 CDS YP_002926907.1 238901111 7956188 complement(1873061..1874047) 1 NC_012759.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1874047 araH 7956188 araH Escherichia coli BW2952 L-arabinose transporter permease YP_002926907.1 1873061 R 595496 CDS YP_002926908.1 238901112 7953692 complement(1874062..1875576) 1 NC_012759.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1875576 araG 7953692 araG Escherichia coli BW2952 L-arabinose transporter ATP-binding protein YP_002926908.1 1874062 R 595496 CDS YP_002926909.1 238901113 7953691 complement(1875646..1876635) 1 NC_012759.1 MG1655 equivalent: b1901; L-arabinose transporter subunit 1876635 araF 7953691 araF Escherichia coli BW2952 L-arabinose transporter subunit YP_002926909.1 1875646 R 595496 CDS YP_002926910.1 238901114 7954116 1877432..1877935 1 NC_012759.1 MG1655 equivalent: b1902; putative ferritin-like protein 1877935 ftnB 7954116 ftnB Escherichia coli BW2952 putative ferritin-like protein YP_002926910.1 1877432 D 595496 CDS YP_002926911.1 238901115 7954870 complement(1878014..1878265) 1 NC_012759.1 MG1655 equivalent: b4537; hypothetical protein 1878265 yecJ 7954870 yecJ Escherichia coli BW2952 hypothetical protein YP_002926911.1 1878014 R 595496 CDS YP_002926912.1 238901116 7952085 1878729..1879052 1 NC_012759.1 MG1655 equivalent: b1904; hypothetical protein 1879052 yecR 7952085 yecR Escherichia coli BW2952 hypothetical protein YP_002926912.1 1878729 D 595496 CDS YP_002926913.1 238901117 7955484 1879223..1879720 1 NC_012759.1 cytoplasmic iron storage protein; ferritin 1879720 ftnA 7955484 ftnA Escherichia coli BW2952 ferritin YP_002926913.1 1879223 D 595496 CDS YP_002926914.1 238901118 7953572 complement(1879758..1879997) 1 NC_012759.1 MG1655 equivalent: b1906; hypothetical protein 1879997 yecH 7953572 yecH Escherichia coli BW2952 hypothetical protein YP_002926914.1 1879758 R 595496 CDS YP_002926915.1 238901119 7955376 1880188..1881399 1 NC_012759.1 MG1655 equivalent: b1907; tyrosine transporter 1881399 tyrP 7955376 tyrP Escherichia coli BW2952 tyrosine transporter YP_002926915.1 1880188 D 595496 CDS YP_002926916.1 238901120 7956223 complement(1881461..1882126) 1 NC_012759.1 MG1655 equivalent: b1908; hypothetical protein 1882126 yecA 7956223 yecA Escherichia coli BW2952 hypothetical protein YP_002926916.1 1881461 R 595496 CDS YP_002926917.1 238901121 7952055 complement(1882776..1883324) 1 NC_012759.1 MG1655 equivalent: b1912; phosphatidylglycerophosphate synthetase 1883324 pgsA 7952055 pgsA Escherichia coli BW2952 phosphatidylglycerophosphate synthetase YP_002926917.1 1882776 R 595496 CDS YP_002926918.1 238901122 7954524 complement(1883381..1885213) 1 NC_012759.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1885213 uvrC 7954524 uvrC Escherichia coli BW2952 excinuclease ABC subunit C YP_002926918.1 1883381 R 595496 CDS YP_002926919.1 238901123 7953536 complement(1885210..1885866) 1 NC_012759.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1885866 uvrY 7953536 uvrY Escherichia coli BW2952 response regulator YP_002926919.1 1885210 R 595496 CDS YP_002926920.1 238901124 7953345 1886325..1886549 1 NC_012759.1 MG1655 equivalent: b1915; hypothetical protein 1886549 yecF 7953345 yecF Escherichia coli BW2952 hypothetical protein YP_002926920.1 1886325 D 595496 CDS YP_002926921.1 238901125 7955485 complement(1886617..1887339) 1 NC_012759.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 1887339 sdiA 7955485 sdiA Escherichia coli BW2952 DNA-binding transcriptional activator SdiA YP_002926921.1 1886617 R 595496 CDS YP_002926922.1 238901126 7953367 complement(1887569..1888321) 1 NC_012759.1 MG1655 equivalent: b1917; putative amino-acid ABC transporter ATP-binding protein YecC 1888321 yecC 7953367 yecC Escherichia coli BW2952 putative amino-acid ABC transporter ATP-binding protein YecC YP_002926922.1 1887569 R 595496 CDS YP_002926923.1 238901127 7955717 complement(1888318..1888986) 1 NC_012759.1 MG1655 equivalent: b1918; putative transporter subunit: membrane component of ABC superfamily 1888986 yecS 7955717 yecS Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002926923.1 1888318 R 595496 CDS YP_002926924.1 238901128 7955728 complement(1889001..1889987) 1 NC_012759.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1889987 dcyD 7955728 dcyD Escherichia coli BW2952 D-cysteine desulfhydrase YP_002926924.1 1889001 R 595496 CDS YP_002926925.1 238901129 7953229 complement(1890092..1890892) 1 NC_012759.1 MG1655 equivalent: b1920; cystine transporter subunit 1890892 fliY 7953229 fliY Escherichia coli BW2952 cystine transporter subunit YP_002926925.1 1890092 R 595496 CDS YP_002926926.1 238901130 7953187 complement(1890980..1891531) 1 NC_012759.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1891531 fliZ 7953187 fliZ Escherichia coli BW2952 flagella biosynthesis protein FliZ YP_002926926.1 1890980 R 595496 CDS YP_002926927.1 238901131 7955564 complement(1891577..1892296) 1 NC_012759.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1892296 fliA 7955564 fliA Escherichia coli BW2952 flagellar biosynthesis sigma factor YP_002926927.1 1891577 R 595496 CDS YP_002926928.1 238901132 7955988 complement(1892617..1894113) 1 NC_012759.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 1894113 fliC 7955988 fliC Escherichia coli BW2952 flagellin YP_002926928.1 1892617 R 595496 CDS YP_002926929.1 238901133 7953595 1894379..1895785 1 NC_012759.1 involved in flagellin assembly; flagellar capping protein 1895785 fliD 7953595 fliD Escherichia coli BW2952 flagellar capping protein YP_002926929.1 1894379 D 595496 CDS YP_002926930.1 238901134 7953594 1895810..1896220 1 NC_012759.1 flagellin specific chaperone; flagellar protein FliS 1896220 fliS 7953594 fliS Escherichia coli BW2952 flagellar protein FliS YP_002926930.1 1895810 D 595496 CDS YP_002926931.1 238901135 7953606 1896220..1896585 1 NC_012759.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 1896585 fliT 7953606 fliT Escherichia coli BW2952 flagellar biosynthesis protein FliT YP_002926931.1 1896220 D 595496 CDS YP_002926932.1 238901136 7954688 1896663..1898150 1 NC_012759.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1898150 amyA 7954688 amyA Escherichia coli BW2952 alpha-amylase YP_002926932.1 1896663 D 595496 CDS YP_002926933.1 238901137 7953200 complement(1898184..1898597) 1 NC_012759.1 MG1655 equivalent: b1928; hypothetical protein 1898597 yedD 7953200 yedD Escherichia coli BW2952 hypothetical protein YP_002926933.1 1898184 R 595496 CDS YP_002926934.1 238901138 7955377 1898784..1899989 1 NC_012759.1 MG1655 equivalent: b1929; putative inner membrane protein 1899989 yedE 7955377 yedE Escherichia coli BW2952 putative inner membrane protein YP_002926934.1 1898784 D 595496 CDS YP_002926935.1 238901139 7955047 1899986..1900219 1 NC_012759.1 MG1655 equivalent: b1930; hypothetical protein 1900219 yedF 7955047 yedF Escherichia coli BW2952 hypothetical protein YP_002926935.1 1899986 D 595496 CDS YP_002926936.1 238901140 7952986 1900328..1900996 1 NC_012759.1 MG1655 equivalent: b1931; hypothetical protein 1900996 yedK 7952986 yedK Escherichia coli BW2952 hypothetical protein YP_002926936.1 1900328 D 595496 CDS YP_002926937.1 238901141 7955486 1901107..1901586 1 NC_012759.1 MG1655 equivalent: b1932; putative acyltransferase 1901586 yedL 7955486 yedL Escherichia coli BW2952 putative acyltransferase YP_002926937.1 1901107 D 595496 CDS YP_002926938.1 238901142 7954614 complement(1903207..1903521) 1 NC_012759.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1903521 fliE 7954614 fliE Escherichia coli BW2952 flagellar hook-basal body protein FliE YP_002926938.1 1903207 R 595496 CDS YP_002926939.1 238901143 7953582 1903736..1905394 1 NC_012759.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1905394 fliF 7953582 fliF Escherichia coli BW2952 flagellar MS-ring protein YP_002926939.1 1903736 D 595496 CDS YP_002926940.1 238901144 7953583 1905387..1906382 1 NC_012759.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1906382 fliG 7953583 fliG Escherichia coli BW2952 flagellar motor switch protein G YP_002926940.1 1905387 D 595496 CDS YP_002926941.1 238901145 7953601 1906375..1907061 1 NC_012759.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1907061 fliH 7953601 fliH Escherichia coli BW2952 flagellar assembly protein H YP_002926941.1 1906375 D 595496 CDS YP_002926942.1 238901146 7953584 1907061..1908434 1 NC_012759.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1908434 fliI 7953584 fliI Escherichia coli BW2952 flagellum-specific ATP synthase YP_002926942.1 1907061 D 595496 CDS YP_002926943.1 238901147 7953607 1908453..1908896 1 NC_012759.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 1908896 fliJ 7953607 fliJ Escherichia coli BW2952 flagellar biosynthesis chaperone YP_002926943.1 1908453 D 595496 CDS YP_002926944.1 238901148 7953604 1908893..1910020 1 NC_012759.1 MG1655 equivalent: b1943; flagellar hook-length control protein 1910020 fliK 7953604 fliK Escherichia coli BW2952 flagellar hook-length control protein YP_002926944.1 1908893 D 595496 CDS YP_002926945.1 238901149 7953600 1910125..1910589 1 NC_012759.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 1910589 fliL 7953600 fliL Escherichia coli BW2952 flagellar basal body-associated protein FliL YP_002926945.1 1910125 D 595496 CDS YP_002926946.1 238901150 7953585 1910594..1911598 1 NC_012759.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1911598 fliM 7953585 fliM Escherichia coli BW2952 flagellar motor switch protein FliM YP_002926946.1 1910594 D 595496 CDS YP_002926947.1 238901151 7953602 1911595..1912008 1 NC_012759.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1912008 fliN 7953602 fliN Escherichia coli BW2952 flagellar motor switch protein FliN YP_002926947.1 1911595 D 595496 CDS YP_002926948.1 238901152 7953603 1912011..1912376 1 NC_012759.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 1912376 fliO 7953603 fliO Escherichia coli BW2952 flagellar biosynthesis protein FliO YP_002926948.1 1912011 D 595496 CDS YP_002926949.1 238901153 7953586 1912376..1913113 1 NC_012759.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1913113 fliP 7953586 fliP Escherichia coli BW2952 flagellar biosynthesis protein FliP YP_002926949.1 1912376 D 595496 CDS YP_002926950.1 238901154 7953587 1913123..1913392 1 NC_012759.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1913392 fliQ 7953587 fliQ Escherichia coli BW2952 flagellar biosynthesis protein FliQ YP_002926950.1 1913123 D 595496 CDS YP_002926951.1 238901155 7953588 1913400..1914185 1 NC_012759.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1914185 fliR 7953588 fliR Escherichia coli BW2952 flagellar biosynthesis protein FliR YP_002926951.1 1913400 D 595496 CDS YP_002926952.1 238901156 7953593 1914475..1915098 1 NC_012759.1 MG1655 equivalent: b1951; DNA-binding transcriptional activator, co-regulator with RcsB 1915098 rcsA 7953593 rcsA Escherichia coli BW2952 DNA-binding transcriptional activator, co-regulator with RcsB YP_002926952.1 1914475 D 595496 CDS YP_002926953.1 238901157 7953395 complement(1915142..1915330) 1 NC_012759.1 MG1655 equivalent: b1952; hypothetical protein 1915330 dsrB 7953395 dsrB Escherichia coli BW2952 hypothetical protein YP_002926953.1 1915142 R 595496 CDS YP_002926954.1 238901158 7955378 1915493..1915720 1 NC_012759.1 MG1655 equivalent: b1953; hypothetical protein 1915720 yodD 7955378 yodD Escherichia coli BW2952 hypothetical protein YP_002926954.1 1915493 D 595496 CDS YP_002926955.1 238901159 7952086 1916018..1916833 1 NC_012759.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1916833 yedP 7952086 yedP Escherichia coli BW2952 mannosyl-3-phosphoglycerate phosphatase YP_002926955.1 1916018 D 595496 CDS YP_002926956.1 238901160 7952987 complement(1916830..1918524) 1 NC_012759.1 MG1655 equivalent: b1956; putative diguanylate cyclase 1918524 yedQ 7952987 yedQ Escherichia coli BW2952 putative diguanylate cyclase YP_002926956.1 1916830 R 595496 CDS YP_002926957.1 238901161 7954723 complement(1918695..1918877) 1 NC_012759.1 MG1655 equivalent: b1957; hypothetical protein 1918877 yodC 7954723 yodC Escherichia coli BW2952 hypothetical protein YP_002926957.1 1918695 R 595496 CDS YP_002926958.1 238901162 7955379 complement(1918956..1919873) 1 NC_012759.1 MG1655 equivalent: b1958; hypothetical protein 1919873 yedI 7955379 yedI Escherichia coli BW2952 hypothetical protein YP_002926958.1 1918956 R 595496 CDS YP_002926959.1 238901163 7952673 1920046..1920966 1 NC_012759.1 MG1655 equivalent: b1959; hypothetical protein 1920966 yedA 7952673 yedA Escherichia coli BW2952 hypothetical protein YP_002926959.1 1920046 D 595496 CDS YP_002926960.1 238901164 7955048 complement(1920955..1921425) 1 NC_012759.1 MG1655 equivalent: b1960; DNA mismatch endonuclease of very short patch repair 1921425 vsr 7955048 vsr Escherichia coli BW2952 DNA mismatch endonuclease of very short patch repair YP_002926960.1 1920955 R 595496 CDS YP_002926961.1 238901165 7953314 complement(1921406..1922824) 1 NC_012759.1 MG1655 equivalent: b1961; DNA cytosine methylase 1922824 dcm 7953314 dcm Escherichia coli BW2952 DNA cytosine methylase YP_002926961.1 1921406 R 595496 CDS YP_002926962.1 238901166 7953302 complement(1922891..1923586) 1 NC_012759.1 MG1655 equivalent: b1962; hypothetical protein 1923586 yedJ 7953302 yedJ Escherichia coli BW2952 hypothetical protein YP_002926962.1 1922891 R 595496 CDS YP_002926963.1 238901167 7955316 complement(1923626..1923991) 1 NC_012759.1 MG1655 equivalent: b1963; putative inner membrane protein 1923991 yedR 7955316 yedR Escherichia coli BW2952 putative inner membrane protein YP_002926963.1 1923626 R 595496 CDS YP_002926964.1 238901168 7952181 1926342..1927193 1 NC_012759.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 1927193 hchA 7952181 hchA Escherichia coli BW2952 chaperone protein HchA YP_002926964.1 1926342 D 595496 CDS YP_002926965.1 238901169 7953924 complement(1927301..1928659) 1 NC_012759.1 MG1655 equivalent: b1968; putative sensory kinase in two-component regulatory system with YedW 1928659 yedV 7953924 yedV Escherichia coli BW2952 putative sensory kinase in two-component regulatory system with YedW YP_002926965.1 1927301 R 595496 CDS YP_002926966.1 238901170 7955586 complement(1928659..1929330) 1 NC_012759.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 1929330 yedW 7955586 yedW Escherichia coli BW2952 transcriptional regulatory protein YedW YP_002926966.1 1928659 R 595496 CDS YP_002926967.1 238901171 7954742 1929463..1929876 1 NC_012759.1 MG1655 equivalent: b1970; hypothetical protein 1929876 yedX 7954742 yedX Escherichia coli BW2952 hypothetical protein YP_002926967.1 1929463 D 595496 CDS YP_002926968.1 238901172 7952988 1929985..1930989 1 NC_012759.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 1930989 yedY 7952988 yedY Escherichia coli BW2952 putative sulfite oxidase subunit YedY YP_002926968.1 1929985 D 595496 CDS YP_002926969.1 238901173 7955557 1930990..1931625 1 NC_012759.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 1931625 yedZ 7955557 yedZ Escherichia coli BW2952 putative sulfite oxidase subunit YedZ YP_002926969.1 1930990 D 595496 CDS YP_002926970.1 238901174 7952715 1931882..1932532 1 NC_012759.1 MG1655 equivalent: b1973; hypothetical protein 1932532 yodA 7952715 yodA Escherichia coli BW2952 hypothetical protein YP_002926970.1 1931882 D 595496 CDS YP_002926971.1 238901175 7952747 1932875..1933405 1 NC_012759.1 MG1655 equivalent: b1974; putative cytochrome 1933405 yodB 7952747 yodB Escherichia coli BW2952 putative cytochrome YP_002926971.1 1932875 D 595496 CDS YP_002926972.1 238901176 7952056 1934158..1934955 1 NC_012759.1 MG1655 equivalent: b1976; hypothetical protein 1934955 mtfA 7952056 mtfA Escherichia coli BW2952 hypothetical protein YP_002926972.1 1934158 D 595496 CDS YP_002926973.1 238901177 7952132 1935445..1942521 1 NC_012759.1 MG1655 equivalent: b1978; adhesin 1942521 yeeJ 7952132 yeeJ Escherichia coli BW2952 adhesin YP_002926973.1 1935445 D 595496 CDS YP_002926974.1 238901178 7952427 1944150..1945466 1 NC_012759.1 MG1655 equivalent: b1981; shikimate transporter 1945466 shiA 7952427 shiA Escherichia coli BW2952 shikimate transporter YP_002926974.1 1944150 D 595496 CDS YP_002926975.1 238901179 7956039 1945568..1947022 1 NC_012759.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 1947022 amn 7956039 amn Escherichia coli BW2952 AMP nucleosidase YP_002926975.1 1945568 D 595496 CDS YP_002926976.1 238901180 7952475 1947365..1948081 1 NC_012759.1 MG1655 equivalent: b1983; hypothetical protein 1948081 yeeN 7952475 yeeN Escherichia coli BW2952 hypothetical protein YP_002926976.1 1947365 D 595496 CDS YP_002926977.1 238901181 7952057 complement(1948710..1950353) 1 NC_012759.1 MG1655 equivalent: b1985; hypothetical protein 1950353 yeeO 7952057 yeeO Escherichia coli BW2952 hypothetical protein YP_002926977.1 1948710 R 595496 CDS YP_002926978.1 238901182 7952133 complement(1950471..1951421) 1 NC_012759.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 1951421 cbl 7952133 cbl Escherichia coli BW2952 transcriptional regulator Cbl YP_002926978.1 1950471 R 595496 CDS YP_002926979.1 238901183 7953389 complement(1951523..1952440) 1 NC_012759.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 1952440 nac 7953389 nac Escherichia coli BW2952 nitrogen assimilation transcriptional regulator YP_002926979.1 1951523 R 595496 CDS YP_002926980.1 238901184 7952134 complement(1952898..1953830) 1 NC_012759.1 MG1655 equivalent: b1990; hypothetical protein 1953830 erfK 7952134 erfK Escherichia coli BW2952 hypothetical protein YP_002926980.1 1952898 R 595496 CDS YP_002926981.1 238901185 7953081 complement(1953895..1954974) 1 NC_012759.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1954974 cobT 7953081 cobT Escherichia coli BW2952 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_002926981.1 1953895 R 595496 CDS YP_002926982.1 238901186 7954384 complement(1954986..1955729) 1 NC_012759.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1955729 cobS 7954384 cobS Escherichia coli BW2952 cobalamin synthase YP_002926982.1 1954986 R 595496 CDS YP_002926983.1 238901187 7952647 complement(1955726..1956271) 1 NC_012759.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1956271 cobU 7952647 cobU Escherichia coli BW2952 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_002926983.1 1955726 R 595496 CDS YP_002926984.1 238901188 7952564 complement(1956812..1957828) 1 NC_012759.1 MG1655 equivalent: b1994; IS5 transposase and trans-activator 1957828 insH 7952564 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002926984.1 1956812 R 595496 CDS YP_002926985.1 238901189 7954040 complement(1959459..1960364) 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 1960364 insD 7954040 insD Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002926985.1 1959459 R 595496 CDS YP_002926986.1 238901190 7954078 complement(1960322..1960687) 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 1960687 insC 7954078 insC Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002926986.1 1960322 R 595496 CDS YP_002926987.1 238901191 7952182 1962046..1965165 1 NC_012759.1 MG1655 equivalent: b2000; CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter 1965165 flu 7952182 flu Escherichia coli BW2952 CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter YP_002926987.1 1962046 D 595496 CDS YP_002926988.1 238901192 7953103 1965286..1966818 1 NC_012759.1 MG1655 equivalent: b2001; CP4-44 prophage; putative membrane protein 1966818 yeeR 7953103 yeeR Escherichia coli BW2952 CP4-44 prophage; putative membrane protein YP_002926988.1 1965286 D 595496 CDS YP_002926989.1 238901193 7953106 1966815..1967261 1 NC_012759.1 MG1655 equivalent: b2002; CP4-44 prophage; putative DNA repair protein 1967261 yeeS 7953106 yeeS Escherichia coli BW2952 CP4-44 prophage; putative DNA repair protein YP_002926989.1 1966815 D 595496 CDS YP_002926990.1 238901194 7953105 1967324..1967545 1 NC_012759.1 MG1655 equivalent: b2003; CP4-44 prophage protein 1967545 yeeT 7953105 yeeT Escherichia coli BW2952 CP4-44 prophage protein YP_002926990.1 1967324 D 595496 CDS YP_002926991.1 238901195 7953107 1967619..1967987 1 NC_012759.1 MG1655 equivalent: b2004; CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 1967987 yeeU 7953107 yeeU Escherichia coli BW2952 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system YP_002926991.1 1967619 D 595496 CDS YP_002926992.1 238901196 7953104 1968076..1968450 1 NC_012759.1 MG1655 equivalent: b2005; CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system 1968450 yeeV 7953104 yeeV Escherichia coli BW2952 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system YP_002926992.1 1968076 D 595496 CDS YP_002926993.1 238901197 7953108 complement(1969539..1969868) 1 NC_012759.1 MG1655 equivalent: b2007; hypothetical protein 1969868 yeeX 7953108 yeeX Escherichia coli BW2952 hypothetical protein YP_002926993.1 1969539 R 595496 CDS YP_002926994.1 238901198 7952822 complement(1970040..1971098) 1 NC_012759.1 MG1655 equivalent: b2008; hypothetical protein 1971098 yeeA 7952822 yeeA Escherichia coli BW2952 hypothetical protein YP_002926994.1 1970040 R 595496 CDS YP_002926995.1 238901199 7952674 complement(1971296..1971769) 1 NC_012759.1 MG1655 equivalent: b2009; DNA gyrase inhibitor 1971769 sbmC 7952674 sbmC Escherichia coli BW2952 DNA gyrase inhibitor YP_002926995.1 1971296 R 595496 CDS YP_002926996.1 238901200 7953307 complement(1971888..1973054) 1 NC_012759.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1973054 dacD 7953307 dacD Escherichia coli BW2952 D-alanyl-D-alanine carboxypeptidase YP_002926996.1 1971888 R 595496 CDS YP_002926997.1 238901201 7953220 1973263..1974690 1 NC_012759.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1974690 sbcB 7953220 sbcB Escherichia coli BW2952 exonuclease I YP_002926997.1 1973263 D 595496 CDS YP_002926998.1 238901202 7953539 complement(1974733..1974960) 1 NC_012759.1 MG1655 equivalent: b2012; hypothetical protein 1974960 yeeD 7953539 yeeD Escherichia coli BW2952 hypothetical protein YP_002926998.1 1974733 R 595496 CDS YP_002926999.1 238901203 7952823 complement(1974974..1976032) 1 NC_012759.1 MG1655 equivalent: b2013; putative inner membrane protein 1976032 yeeE 7952823 yeeE Escherichia coli BW2952 putative inner membrane protein YP_002926999.1 1974974 R 595496 CDS YP_002927000.1 238901204 7955000 complement(1976211..1977569) 1 NC_012759.1 MG1655 equivalent: b2014; putative amino-acid transporter 1977569 yeeF 7955000 yeeF Escherichia coli BW2952 putative amino-acid transporter YP_002927000.1 1976211 R 595496 CDS YP_002927001.1 238901205 7954641 complement(1977836..1978765) 1 NC_012759.1 MG1655 equivalent: b2015; putative DNA-binding transcriptional regulator 1978765 yeeY 7954641 yeeY Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927001.1 1977836 R 595496 CDS YP_002927002.1 238901206 7954765 complement(1978811..1979635) 1 NC_012759.1 MG1655 equivalent: b2016; putative epimerase, with NAD(P)-binding Rossmann-fold domain 1979635 yeeZ 7954765 yeeZ Escherichia coli BW2952 putative epimerase, with NAD(P)-binding Rossmann-fold domain YP_002927002.1 1978811 R 595496 CDS YP_002927003.1 238901207 7954860 complement(1979718..1979972) 1 NC_012759.1 MG1655 equivalent: b4539; toxin of the YoeB-YefM toxin-antitoxin system 1979972 yoeB 7954860 yoeB Escherichia coli BW2952 toxin of the YoeB-YefM toxin-antitoxin system YP_002927003.1 1979718 R 595496 CDS YP_002927004.1 238901208 7956162 complement(1979969..1980220) 1 NC_012759.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 1980220 yefM 7956162 yefM Escherichia coli BW2952 antitoxin YefM YP_002927004.1 1979969 R 595496 CDS YP_002927006.1 238901210 7953908 1980699..1981598 1 NC_012759.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1981598 hisG 7953908 hisG Escherichia coli BW2952 ATP phosphoribosyltransferase YP_002927006.1 1980699 D 595496 CDS YP_002927007.1 238901211 7952521 1981604..1982908 1 NC_012759.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1982908 hisD 7952521 hisD Escherichia coli BW2952 histidinol dehydrogenase YP_002927007.1 1981604 D 595496 CDS YP_002927008.1 238901212 7952569 1982905..1983975 1 NC_012759.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1983975 hisC 7952569 hisC Escherichia coli BW2952 histidinol-phosphate aminotransferase YP_002927008.1 1982905 D 595496 CDS YP_002927009.1 238901213 7953913 1983975..1985042 1 NC_012759.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1985042 hisB 7953913 hisB Escherichia coli BW2952 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002927009.1 1983975 D 595496 CDS YP_002927010.1 238901214 7953687 1985042..1985632 1 NC_012759.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1985632 hisH 7953687 hisH Escherichia coli BW2952 imidazole glycerol phosphate synthase subunit HisH YP_002927010.1 1985042 D 595496 CDS YP_002927011.1 238901215 7953992 1985632..1986369 1 NC_012759.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1986369 hisA 7953992 hisA Escherichia coli BW2952 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002927011.1 1985632 D 595496 CDS YP_002927012.1 238901216 7954326 1986351..1987127 1 NC_012759.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1987127 hisF 7954326 hisF Escherichia coli BW2952 imidazole glycerol phosphate synthase subunit HisF YP_002927012.1 1986351 D 595496 CDS YP_002927013.1 238901217 7953991 1987121..1987732 1 NC_012759.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1987732 hisI 7953991 hisI Escherichia coli BW2952 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_002927013.1 1987121 D 595496 CDS YP_002927014.1 238901218 7953706 complement(1987828..1988808) 1 NC_012759.1 MG1655 equivalent: b2027; regulator of length of O-antigen component of lipopolysaccharide chains 1988808 cld 7953706 cld Escherichia coli BW2952 regulator of length of O-antigen component of lipopolysaccharide chains YP_002927014.1 1987828 R 595496 CDS YP_002927015.1 238901219 7955920 complement(1988954..1990120) 1 NC_012759.1 MG1655 equivalent: b2028; UDP-glucose 6-dehydrogenase 1990120 ugd 7955920 ugd Escherichia coli BW2952 UDP-glucose 6-dehydrogenase YP_002927015.1 1988954 R 595496 CDS YP_002927016.1 238901220 7956234 complement(1990369..1991775) 1 NC_012759.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1991775 gnd 7956234 gnd Escherichia coli BW2952 6-phosphogluconate dehydrogenase YP_002927016.1 1990369 R 595496 CDS YP_002927017.1 238901221 7953801 complement(1992402..1993418) 1 NC_012759.1 MG1655 equivalent: b2030; IS5 transposase and trans-activator 1993418 insH 7953801 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002927017.1 1992402 R 595496 CDS YP_002927018.1 238901222 7954041 complement(1993898..1995016) 1 NC_012759.1 MG1655 equivalent: b2032; lipopolysaccharide biosynthesis protein 1995016 wbbK 7954041 wbbK Escherichia coli BW2952 lipopolysaccharide biosynthesis protein YP_002927018.1 1993898 R 595496 CDS YP_002927019.1 238901223 7954149 complement(1995001..1995591) 1 NC_012759.1 WbbJ; catalyzes the transfer of the O-acetyl moiety to the O antigen; part of the lipopolysaccharide biosynthetic pathway; putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ 1995591 wbbJ 7954149 wbbJ Escherichia coli BW2952 putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ YP_002927019.1 1995001 R 595496 CDS YP_002927020.1 238901224 7954606 complement(1995572..1996564) 1 NC_012759.1 MG1655 equivalent: b2034; hypothetical protein 1996564 wbbI 7954606 wbbI Escherichia coli BW2952 hypothetical protein YP_002927020.1 1995572 R 595496 CDS YP_002927021.1 238901225 7952824 complement(1996567..1997733) 1 NC_012759.1 MG1655 equivalent: b2035; O-antigen polymerase 1997733 rfc 7952824 rfc Escherichia coli BW2952 O-antigen polymerase YP_002927021.1 1996567 R 595496 CDS YP_002927022.1 238901226 7954418 complement(1997733..1998836) 1 NC_012759.1 MG1655 equivalent: b2036; UDP-galactopyranose mutase, FAD/NAD(P)-binding 1998836 glf 7954418 glf Escherichia coli BW2952 UDP-galactopyranose mutase, FAD/NAD(P)-binding YP_002927022.1 1997733 R 595496 CDS YP_002927023.1 238901227 7956231 complement(1998844..2000091) 1 NC_012759.1 MG1655 equivalent: b2037; putative polisoprenol-linked O-antigen transporter 2000091 rfbX 7956231 rfbX Escherichia coli BW2952 putative polisoprenol-linked O-antigen transporter YP_002927023.1 1998844 R 595496 CDS YP_002927024.1 238901228 7955324 complement(2000088..2000645) 1 NC_012759.1 MG1655 equivalent: b2038; dTDP-4-deoxyrhamnose-3,5-epimerase 2000645 rfbC 7955324 rfbC Escherichia coli BW2952 dTDP-4-deoxyrhamnose-3,5-epimerase YP_002927024.1 2000088 R 595496 CDS YP_002927025.1 238901229 7953502 complement(2000645..2001526) 1 NC_012759.1 MG1655 equivalent: b2039; glucose-1-phosphate thymidylyltransferase 2001526 rfbA 7953502 rfbA Escherichia coli BW2952 glucose-1-phosphate thymidylyltransferase YP_002927025.1 2000645 R 595496 CDS YP_002927026.1 238901230 7953806 complement(2001584..2002483) 1 NC_012759.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase 2002483 rfbD 7953806 rfbD Escherichia coli BW2952 dTDP-4-dehydrorhamnose reductase YP_002927026.1 2001584 R 595496 CDS YP_002927027.1 238901231 7953501 complement(2002483..2003568) 1 NC_012759.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase 2003568 rfbB 7953501 rfbB Escherichia coli BW2952 dTDP-glucose-4,6-dehydratase YP_002927027.1 2002483 R 595496 CDS YP_002927028.1 238901232 7953503 complement(2003941..2004834) 1 NC_012759.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 2004834 galF 7953503 galF Escherichia coli BW2952 UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_002927028.1 2003941 R 595496 CDS YP_002927029.1 238901233 7955602 complement(2005009..2006403) 1 NC_012759.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein 2006403 wcaM 7955602 wcaM Escherichia coli BW2952 putative colanic acid biosynthesis protein YP_002927029.1 2005009 R 595496 CDS YP_002927030.1 238901234 7954699 complement(2006414..2007634) 1 NC_012759.1 MG1655 equivalent: b2044; putative glycosyl transferase 2007634 wcaL 7954699 wcaL Escherichia coli BW2952 putative glycosyl transferase YP_002927030.1 2006414 R 595496 CDS YP_002927031.1 238901235 7954933 complement(2007631..2008911) 1 NC_012759.1 MG1655 equivalent: b2045; putative pyruvyl transferase 2008911 wcaK 7954933 wcaK Escherichia coli BW2952 putative pyruvyl transferase YP_002927031.1 2007631 R 595496 CDS YP_002927032.1 238901236 7955553 complement(2009187..2010665) 1 NC_012759.1 MG1655 equivalent: b2046; colanic acid exporter 2010665 wzxC 7955553 wzxC Escherichia coli BW2952 colanic acid exporter YP_002927032.1 2009187 R 595496 CDS YP_002927033.1 238901237 7952651 complement(2010667..2012061) 1 NC_012759.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase 2012061 wcaJ 7952651 wcaJ Escherichia coli BW2952 putative UDP-glucose lipid carrier transferase YP_002927033.1 2010667 R 595496 CDS YP_002927034.1 238901238 7955745 complement(2012116..2013486) 1 NC_012759.1 MG1655 equivalent: b2048; phosphomannomutase 2013486 cpsG 7955745 cpsG Escherichia coli BW2952 phosphomannomutase YP_002927034.1 2012116 R 595496 CDS YP_002927035.1 238901239 7954542 complement(2013591..2015027) 1 NC_012759.1 MG1655 equivalent: b2049; mannose-1-phosphate guanyltransferase 2015027 cpsB 7954542 cpsB Escherichia coli BW2952 mannose-1-phosphate guanyltransferase YP_002927035.1 2013591 R 595496 CDS YP_002927036.1 238901240 7954214 complement(2015030..2016253) 1 NC_012759.1 MG1655 equivalent: b2050; putative glycosyl transferase 2016253 wcaI 7954214 wcaI Escherichia coli BW2952 putative glycosyl transferase YP_002927036.1 2015030 R 595496 CDS YP_002927037.1 238901241 7954934 complement(2016250..2016729) 1 NC_012759.1 MG1655 equivalent: b2051; GDP-mannose mannosyl hydrolase 2016729 gmm 7954934 gmm Escherichia coli BW2952 GDP-mannose mannosyl hydrolase YP_002927037.1 2016250 R 595496 CDS YP_002927038.1 238901242 7953777 complement(2016732..2017697) 1 NC_012759.1 MG1655 equivalent: b2052; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase 2017697 fcl 7953777 fcl Escherichia coli BW2952 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase YP_002927038.1 2016732 R 595496 CDS YP_002927039.1 238901243 7952568 complement(2017700..2018821) 1 NC_012759.1 MG1655 equivalent: b2053; GDP-D-mannose dehydratase, NAD(P)-binding 2018821 gmd 7952568 gmd Escherichia coli BW2952 GDP-D-mannose dehydratase, NAD(P)-binding YP_002927039.1 2017700 R 595496 CDS YP_002927040.1 238901244 7953776 complement(2018847..2019395) 1 NC_012759.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF 2019395 wcaF 7953776 wcaF Escherichia coli BW2952 putative colanic acid biosynthesis acetyltransferase WcaF YP_002927040.1 2018847 R 595496 CDS YP_002927041.1 238901245 7954607 complement(2019411..2020157) 1 NC_012759.1 MG1655 equivalent: b2055; putative glycosyl transferase 2020157 wcaE 7954607 wcaE Escherichia coli BW2952 putative glycosyl transferase YP_002927041.1 2019411 R 595496 CDS YP_002927042.1 238901246 7954935 complement(2020168..2021385) 1 NC_012759.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 2021385 wcaD 7954935 wcaD Escherichia coli BW2952 putative colanic acid biosynthesis protein YP_002927042.1 2020168 R 595496 CDS YP_002927043.1 238901247 7954700 complement(2021360..2022577) 1 NC_012759.1 MG1655 equivalent: b2057; putative glycosyl transferase 2022577 wcaC 7954700 wcaC Escherichia coli BW2952 putative glycosyl transferase YP_002927043.1 2021360 R 595496 CDS YP_002927044.1 238901248 7954936 complement(2022574..2023062) 1 NC_012759.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB 2023062 wcaB 7954936 wcaB Escherichia coli BW2952 putative colanic acid biosynthesis acetyltransferase WcaB YP_002927044.1 2022574 R 595496 CDS YP_002927045.1 238901249 7954608 complement(2023065..2023904) 1 NC_012759.1 MG1655 equivalent: b2059; putative glycosyl transferase 2023904 wcaA 7954608 wcaA Escherichia coli BW2952 putative glycosyl transferase YP_002927045.1 2023065 R 595496 CDS YP_002927046.1 238901250 7954937 complement(2023997..2026159) 1 NC_012759.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2026159 wzc 7954937 wzc Escherichia coli BW2952 tyrosine kinase YP_002927046.1 2023997 R 595496 CDS YP_002927047.1 238901251 7955812 complement(2026162..2026605) 1 NC_012759.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2026605 wzb 7955812 wzb Escherichia coli BW2952 tyrosine phosphatase YP_002927047.1 2026162 R 595496 CDS YP_002927048.1 238901252 7955813 complement(2026611..2027750) 1 NC_012759.1 MG1655 equivalent: b2062; lipoprotein required for capsular polysaccharide translocation through the outer membrane 2027750 wza 7955813 wza Escherichia coli BW2952 lipoprotein required for capsular polysaccharide translocation through the outer membrane YP_002927048.1 2026611 R 595496 CDS YP_002927049.1 238901253 7954158 2028409..2029992 1 NC_012759.1 MG1655 equivalent: b2063; fused putative membrane protein/putative membrane protein 2029992 yegH 7954158 yegH Escherichia coli BW2952 fused putative membrane protein/putative membrane protein YP_002927049.1 2028409 D 595496 CDS YP_002927050.1 238901254 7953714 complement(2030266..2032119) 1 NC_012759.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein 2032119 asmA 7953714 asmA Escherichia coli BW2952 putative assembly protein YP_002927050.1 2030266 R 595496 CDS YP_002927051.1 238901255 7954660 complement(2032141..2032722) 1 NC_012759.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2032722 dcd 7954660 dcd Escherichia coli BW2952 deoxycytidine triphosphate deaminase YP_002927051.1 2032141 R 595496 CDS YP_002927052.1 238901256 7952256 complement(2032814..2033455) 1 NC_012759.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2033455 udk 7952256 udk Escherichia coli BW2952 uridine kinase YP_002927052.1 2032814 R 595496 CDS YP_002927053.1 238901257 7956263 2033773..2037090 1 NC_012759.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 2037090 yegE 7956263 yegE Escherichia coli BW2952 putative sensor protein YP_002927053.1 2033773 D 595496 CDS YP_002927054.1 238901258 7954734 complement(2037199..2038047) 1 NC_012759.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2038047 alkA 7954734 alkA Escherichia coli BW2952 3-methyladenine DNA glycosylase YP_002927054.1 2037199 R 595496 CDS YP_002927055.1 238901259 7952314 2038181..2039533 1 NC_012759.1 MG1655 equivalent: b2069; putative chaperone 2039533 yegD 7952314 yegD Escherichia coli BW2952 putative chaperone YP_002927055.1 2038181 D 595496 CDS YP_002927056.1 238901260 7954689 complement(2039546..2041492) 1 NC_012759.1 MG1655 equivalent: b2070; hypothetical protein 2041492 yegI 7954689 yegI Escherichia coli BW2952 hypothetical protein YP_002927056.1 2039546 R 595496 CDS YP_002927057.1 238901261 7952825 2041692..2042153 1 NC_012759.1 MG1655 equivalent: b2071; hypothetical protein 2042153 yegJ 7952825 yegJ Escherichia coli BW2952 hypothetical protein YP_002927057.1 2041692 D 595496 CDS YP_002927058.1 238901262 7955488 complement(2042218..2042979) 1 NC_012759.1 MG1655 equivalent: b2072; hypothetical protein 2042979 yegK 7955488 yegK Escherichia coli BW2952 hypothetical protein YP_002927058.1 2042218 R 595496 CDS YP_002927059.1 238901263 7955380 complement(2042976..2043635) 1 NC_012759.1 MG1655 equivalent: b2073; hypothetical protein 2043635 yegL 7955380 yegL Escherichia coli BW2952 hypothetical protein YP_002927059.1 2042976 R 595496 CDS YP_002927060.1 238901264 7952184 2044523..2045770 1 NC_012759.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2045770 mdtA 7952184 mdtA Escherichia coli BW2952 multidrug efflux system subunit MdtA YP_002927060.1 2044523 D 595496 CDS YP_002927061.1 238901265 7954311 2045770..2048892 1 NC_012759.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2048892 mdtB 7954311 mdtB Escherichia coli BW2952 multidrug efflux system subunit MdtB YP_002927061.1 2045770 D 595496 CDS YP_002927062.1 238901266 7954312 2048893..2051970 1 NC_012759.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2051970 mdtC 7954312 mdtC Escherichia coli BW2952 multidrug efflux system subunit MdtC YP_002927062.1 2048893 D 595496 CDS YP_002927063.1 238901267 7954313 2051971..2053386 1 NC_012759.1 MG1655 equivalent: b2077; multidrug efflux system protein MdtE 2053386 mdtD 7954313 mdtD Escherichia coli BW2952 multidrug efflux system protein MdtE YP_002927063.1 2051971 D 595496 CDS YP_002927064.1 238901268 7954302 2053383..2054786 1 NC_012759.1 MG1655 equivalent: b2078; signal transduction histidine-protein kinase BaeS 2054786 baeS 7954302 baeS Escherichia coli BW2952 signal transduction histidine-protein kinase BaeS YP_002927064.1 2053383 D 595496 CDS YP_002927065.1 238901269 7956012 2054783..2055505 1 NC_012759.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2055505 baeR 7956012 baeR Escherichia coli BW2952 DNA-binding transcriptional regulator BaeR YP_002927065.1 2054783 D 595496 CDS YP_002927066.1 238901270 7953344 2055696..2056028 1 NC_012759.1 MG1655 equivalent: b2080; hypothetical protein 2056028 yegP 7953344 yegP Escherichia coli BW2952 hypothetical protein YP_002927066.1 2055696 D 595496 CDS YP_002927067.1 238901271 7955489 2056175..2057536 1 NC_012759.1 MG1655 equivalent: b2081; putative peptidase 2057536 yegQ 7955489 yegQ Escherichia coli BW2952 putative peptidase YP_002927067.1 2056175 D 595496 CDS YP_002927068.1 238901272 7952185 complement(2057809..2058027) 1 NC_012759.1 in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator 2058027 ogrK 7952185 ogrK Escherichia coli BW2952 DNA-binding transcriptional regulator YP_002927068.1 2057809 R 595496 CDS YP_002927069.1 238901273 7953448 complement(2058496..2058813) 1 NC_012759.1 MG1655 equivalent: b2085; hypothetical protein 2058813 yegR 7953448 yegR Escherichia coli BW2952 hypothetical protein YP_002927069.1 2058496 R 595496 CDS YP_002927070.1 238901274 7955381 2059219..2060118 1 NC_012759.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2060118 yegS 7955381 yegS Escherichia coli BW2952 lipid kinase YP_002927070.1 2059219 D 595496 CDS YP_002927071.1 238901275 7954520 2060734..2061042 1 NC_012759.1 MG1655 equivalent: b2088; IS3 element protein InsE 2061042 insE 7954520 insE Escherichia coli BW2952 IS3 element protein InsE YP_002927071.1 2060734 D 595496 CDS YP_002927072.1 238901276 7954031 2061039..2061905 1 NC_012759.1 MG1655 equivalent: b2089; IS3 element protein InsF 2061905 insF 7954031 insF Escherichia coli BW2952 IS3 element protein InsF YP_002927072.1 2061039 D 595496 CDS YP_002927073.1 238901277 7954035 complement(2062340..2063380) 1 NC_012759.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2063380 gatD 7954035 gatD Escherichia coli BW2952 galactitol-1-phosphate dehydrogenase YP_002927073.1 2062340 R 595496 CDS YP_002927074.1 238901278 7953754 complement(2063428..2064783) 1 NC_012759.1 MG1655 equivalent: b2092; PTS system galactitol-specific transporter subunit IIC 2064783 gatC 7953754 gatC Escherichia coli BW2952 PTS system galactitol-specific transporter subunit IIC YP_002927074.1 2063428 R 595496 CDS YP_002927075.1 238901279 7953757 complement(2064787..2065071) 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2065071 gatB 7953757 gatB Escherichia coli BW2952 PTS system galactitol-specific transporter subunit IIB YP_002927075.1 2064787 R 595496 CDS YP_002927076.1 238901280 7953756 complement(2065102..2065554) 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2065554 gatA 7953756 gatA Escherichia coli BW2952 PTS system galactitol-specific transporter subunit IIA YP_002927076.1 2065102 R 595496 CDS YP_002927077.1 238901281 7953755 complement(2065564..2066826) 1 NC_012759.1 MG1655 equivalent: b2095; D-tagatose 1,6-bisphosphate aldolase 2, subunit 2066826 gatZ 7953755 gatZ Escherichia coli BW2952 D-tagatose 1,6-bisphosphate aldolase 2, subunit YP_002927077.1 2065564 R 595496 CDS YP_002927078.1 238901282 7953500 complement(2066855..2067709) 1 NC_012759.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2067709 gatY 7953500 gatY Escherichia coli BW2952 tagatose-bisphosphate aldolase YP_002927078.1 2066855 R 595496 CDS YP_002927079.1 238901283 7953499 complement(2068017..2069069) 1 NC_012759.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2069069 fbaB 7953499 fbaB Escherichia coli BW2952 fructose-bisphosphate aldolase YP_002927079.1 2068017 R 595496 CDS YP_002927080.1 238901284 7953637 2069326..2070603 1 NC_012759.1 MG1655 equivalent: b2098; putative nucleoside transporter 2070603 yegT 7953637 yegT Escherichia coli BW2952 putative nucleoside transporter YP_002927080.1 2069326 D 595496 CDS YP_002927081.1 238901285 7955185 2070600..2071604 1 NC_012759.1 MG1655 equivalent: b2099; putative hydrolase 2071604 yegU 7955185 yegU Escherichia coli BW2952 putative hydrolase YP_002927081.1 2070600 D 595496 CDS YP_002927082.1 238901286 7954968 2071601..2072566 1 NC_012759.1 MG1655 equivalent: b2100; putative kinase 2072566 yegV 7954968 yegV Escherichia coli BW2952 putative kinase YP_002927082.1 2071601 D 595496 CDS YP_002927083.1 238901287 7955094 complement(2072540..2073286) 1 NC_012759.1 MG1655 equivalent: b2101; putative DNA-binding transcriptional regulator 2073286 yegW 7955094 yegW Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927083.1 2072540 R 595496 CDS YP_002927084.1 238901288 7954766 complement(2073338..2074156) 1 NC_012759.1 MG1655 equivalent: b2102; putative hydrolase 2074156 yegX 7954766 yegX Escherichia coli BW2952 putative hydrolase YP_002927084.1 2073338 R 595496 CDS YP_002927085.1 238901289 7954956 complement(2074221..2075021) 1 NC_012759.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2075021 thiD 7954956 thiD Escherichia coli BW2952 phosphomethylpyrimidine kinase YP_002927085.1 2074221 R 595496 CDS YP_002927086.1 238901290 7952570 complement(2075018..2075806) 1 NC_012759.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2075806 thiM 7952570 thiM Escherichia coli BW2952 hydroxyethylthiazole kinase YP_002927086.1 2075018 R 595496 CDS YP_002927087.1 238901291 7953934 complement(2076029..2076301) 1 NC_012759.1 MG1655 equivalent: b2105; hypothetical protein 2076301 rcnR 7953934 rcnR Escherichia coli BW2952 hypothetical protein YP_002927087.1 2076029 R 595496 CDS YP_002927088.1 238901292 7952827 2076422..2077246 1 NC_012759.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2077246 rcnA 7952827 rcnA Escherichia coli BW2952 nickel/cobalt efflux protein RcnA YP_002927088.1 2076422 D 595496 CDS YP_002927089.1 238901293 7954228 2077465..2077803 1 NC_012759.1 MG1655 equivalent: b2107; hypothetical protein 2077803 yohN 7954228 yohN Escherichia coli BW2952 hypothetical protein YP_002927089.1 2077465 D 595496 CDS YP_002927090.1 238901294 7955490 complement(2077885..2078919) 1 NC_012759.1 MG1655 equivalent: b2108; putative fimbrial-like adhesin protein 2078919 yehA 7955490 yehA Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002927090.1 2077885 R 595496 CDS YP_002927091.1 238901295 7954886 complement(2078935..2081415) 1 NC_012759.1 MG1655 equivalent: b2109; putative outer membrane protein 2081415 yehB 7954886 yehB Escherichia coli BW2952 putative outer membrane protein YP_002927091.1 2078935 R 595496 CDS YP_002927092.1 238901296 7955212 complement(2081431..2082150) 1 NC_012759.1 MG1655 equivalent: b2110; putative periplasmic pilin chaperone 2082150 yehC 7955212 yehC Escherichia coli BW2952 putative periplasmic pilin chaperone YP_002927092.1 2081431 R 595496 CDS YP_002927093.1 238901297 7955301 complement(2082185..2082727) 1 NC_012759.1 MG1655 equivalent: b2111; putative fimbrial-like adhesin protein 2082727 yehD 7955301 yehD Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002927093.1 2082185 R 595496 CDS YP_002927094.1 238901298 7954887 complement(2083020..2083301) 1 NC_012759.1 MG1655 equivalent: b2112; hypothetical protein 2083301 yehE 7954887 yehE Escherichia coli BW2952 hypothetical protein YP_002927094.1 2083020 R 595496 CDS YP_002927095.1 238901299 7955382 complement(2083564..2084673) 1 NC_012759.1 MG1655 equivalent: b2113; putative ATPase 2084673 mrp 7955382 mrp Escherichia coli BW2952 putative ATPase YP_002927095.1 2083564 R 595496 CDS YP_002927096.1 238901300 7952481 2084805..2086838 1 NC_012759.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2086838 metG 7952481 metG Escherichia coli BW2952 methionyl-tRNA synthetase YP_002927096.1 2084805 D 595496 CDS YP_002927097.1 238901301 7954247 2090784..2094416 1 NC_012759.1 MG1655 equivalent: b2118; hypothetical protein 2094416 yehI 7954247 yehI Escherichia coli BW2952 hypothetical protein YP_002927097.1 2090784 D 595496 CDS YP_002927098.1 238901302 7952991 2094477..2094794 1 NC_012759.1 MG1655 equivalent: b4541; hypothetical protein 2094794 yehK 7952991 yehK Escherichia coli BW2952 hypothetical protein YP_002927098.1 2094477 D 595496 CDS YP_002927099.1 238901303 7955532 2095101..2096189 1 NC_012759.1 MG1655 equivalent: b2119; putative transporter subunit: ATP-binding component of ABC superfamily 2096189 yehL 7955532 yehL Escherichia coli BW2952 putative transporter subunit: ATP-binding component of ABC superfamily YP_002927099.1 2095101 D 595496 CDS YP_002927100.1 238901304 7955724 2096200..2098479 1 NC_012759.1 MG1655 equivalent: b2120; hypothetical protein 2098479 yehM 7955724 yehM Escherichia coli BW2952 hypothetical protein YP_002927100.1 2096200 D 595496 CDS YP_002927101.1 238901305 7955491 2098472..2099608 1 NC_012759.1 MG1655 equivalent: b2121; hypothetical protein 2099608 yehP 7955491 yehP Escherichia coli BW2952 hypothetical protein YP_002927101.1 2098472 D 595496 CDS YP_002927102.1 238901306 7952992 2101730..2102191 1 NC_012759.1 MG1655 equivalent: b2123; hypothetical protein 2102191 yehR 7952992 yehR Escherichia coli BW2952 hypothetical protein YP_002927102.1 2101730 D 595496 CDS YP_002927103.1 238901307 7952993 complement(2102231..2102701) 1 NC_012759.1 MG1655 equivalent: b2124; hypothetical protein 2102701 yehS 7952993 yehS Escherichia coli BW2952 hypothetical protein YP_002927103.1 2102231 R 595496 CDS YP_002927104.1 238901308 7952828 complement(2102748..2103467) 1 NC_012759.1 unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 2103467 yehT 7952828 yehT Escherichia coli BW2952 putative two-component response-regulatory protein YehT YP_002927104.1 2102748 R 595496 CDS YP_002927105.1 238901309 7955567 complement(2103464..2105149) 1 NC_012759.1 MG1655 equivalent: b2126; putative sensory kinase in two-component system with YehT 2105149 yehU 7955567 yehU Escherichia coli BW2952 putative sensory kinase in two-component system with YehT YP_002927105.1 2103464 R 595496 CDS YP_002927106.1 238901310 7955588 2105371..2106102 1 NC_012759.1 MG1655 equivalent: b2127; DNA-binding transcriptional regulator 2106102 mlrA 7955588 mlrA Escherichia coli BW2952 DNA-binding transcriptional regulator YP_002927106.1 2105371 D 595496 CDS YP_002927107.1 238901311 7953444 2106162..2106269 1 NC_012759.1 MG1655 equivalent: b4542; hypothetical protein 2106269 yohO 7953444 yohO Escherichia coli BW2952 hypothetical protein YP_002927107.1 2106162 D 595496 CDS YP_002927108.1 238901312 7955533 complement(2106250..2106981) 1 NC_012759.1 MG1655 equivalent: b2128; putative transporter subunit: membrane component of ABC superfamily 2106981 yehW 7955533 yehW Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002927108.1 2106250 R 595496 CDS YP_002927109.1 238901313 7955729 complement(2106986..2107912) 1 NC_012759.1 MG1655 equivalent: b2129; putative transporter subunit: ATP-binding component of ABC superfamily 2107912 yehX 7955729 yehX Escherichia coli BW2952 putative transporter subunit: ATP-binding component of ABC superfamily YP_002927109.1 2106986 R 595496 CDS YP_002927110.1 238901314 7955718 complement(2107905..2109062) 1 NC_012759.1 MG1655 equivalent: b2130; putative transporter subunit: membrane component of ABC superfamily 2109062 yehY 7955718 yehY Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002927110.1 2107905 R 595496 CDS YP_002927111.1 238901315 7955730 complement(2109069..2109986) 1 NC_012759.1 MG1655 equivalent: b2131; putative transporter subunit: periplasmic-binding component of ABC superfamily 2109986 osmF 7955730 osmF Escherichia coli BW2952 putative transporter subunit: periplasmic-binding component of ABC superfamily YP_002927111.1 2109069 R 595496 CDS YP_002927112.1 238901316 7955735 complement(2110197..2112494) 1 NC_012759.1 MG1655 equivalent: b2132; beta-D-glucoside glucohydrolase, periplasmic 2112494 bglX 7955735 bglX Escherichia coli BW2952 beta-D-glucoside glucohydrolase, periplasmic YP_002927112.1 2110197 R 595496 CDS YP_002927113.1 238901317 7952546 2112690..2114405 1 NC_012759.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2114405 dld 7952546 dld Escherichia coli BW2952 D-lactate dehydrogenase YP_002927113.1 2112690 D 595496 CDS YP_002927114.1 238901318 7953272 complement(2114443..2115375) 1 NC_012759.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2115375 pbpG 7953272 pbpG Escherichia coli BW2952 D-alanyl-D-alanine endopeptidase YP_002927114.1 2114443 R 595496 CDS YP_002927115.1 238901319 7953221 complement(2115549..2116136) 1 NC_012759.1 MG1655 equivalent: b2135; putative inner membrane protein 2116136 yohC 7953221 yohC Escherichia coli BW2952 putative inner membrane protein YP_002927115.1 2115549 R 595496 CDS YP_002927116.1 238901320 7955001 2116306..2116884 1 NC_012759.1 MG1655 equivalent: b2136; hypothetical protein 2116884 yohD 7955001 yohD Escherichia coli BW2952 hypothetical protein YP_002927116.1 2116306 D 595496 CDS YP_002927117.1 238901321 7952716 complement(2117014..2117775) 1 NC_012759.1 MG1655 equivalent: b2137; acetoin dehydrogenase 2117775 yohF 7952716 yohF Escherichia coli BW2952 acetoin dehydrogenase YP_002927117.1 2117014 R 595496 CDS YP_002927118.1 238901322 7955246 complement(2119943..2120890) 1 NC_012759.1 MG1655 equivalent: b2140; tRNA-dihydrouridine synthase C 2120890 dusC 7955246 dusC Escherichia coli BW2952 tRNA-dihydrouridine synthase C YP_002927118.1 2119943 R 595496 CDS YP_002927119.1 238901323 7956206 2121129..2121527 1 NC_012759.1 MG1655 equivalent: b2141; hypothetical protein 2121527 yohJ 7956206 yohJ Escherichia coli BW2952 hypothetical protein YP_002927119.1 2121129 D 595496 CDS YP_002927120.1 238901324 7952717 2121524..2122219 1 NC_012759.1 MG1655 equivalent: b2142; hypothetical protein 2122219 yohK 7952717 yohK Escherichia coli BW2952 hypothetical protein YP_002927120.1 2121524 D 595496 CDS YP_002927121.1 238901325 7955049 2122349..2123233 1 NC_012759.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2123233 cdd 7955049 cdd Escherichia coli BW2952 cytidine deaminase YP_002927121.1 2122349 D 595496 CDS YP_002927122.1 238901326 7953188 2123383..2124102 1 NC_012759.1 MG1655 equivalent: b2144; hypothetical protein 2124102 sanA 7953188 sanA Escherichia coli BW2952 hypothetical protein YP_002927122.1 2123383 D 595496 CDS YP_002927123.1 238901327 7955492 2124105..2124344 1 NC_012759.1 MG1655 equivalent: b2145; putative inner membrane protein 2124344 yeiS 7955492 yeiS Escherichia coli BW2952 putative inner membrane protein YP_002927123.1 2124105 D 595496 CDS YP_002927124.1 238901328 7955050 2124538..2125776 1 NC_012759.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2125776 yeiT 7955050 yeiT Escherichia coli BW2952 putative oxidoreductase YP_002927124.1 2124538 D 595496 CDS YP_002927125.1 238901329 7955234 2125770..2127005 1 NC_012759.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2127005 yeiA 7955234 yeiA Escherichia coli BW2952 dihydropyrimidine dehydrogenase YP_002927125.1 2125770 D 595496 CDS YP_002927126.1 238901330 7955235 complement(2127248..2128258) 1 NC_012759.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 2128258 mglC 7955235 mglC Escherichia coli BW2952 beta-methylgalactoside transporter inner membrane protein YP_002927126.1 2127248 R 595496 CDS YP_002927127.1 238901331 7954257 complement(2128274..2129794) 1 NC_012759.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2129794 mglA 7954257 mglA Escherichia coli BW2952 galactose/methyl galaxtoside transporter ATP-binding protein YP_002927127.1 2128274 R 595496 CDS YP_002927128.1 238901332 7953700 complement(2129855..2130853) 1 NC_012759.1 MG1655 equivalent: b2150; methyl-galactoside transporter subunit 2130853 mglB 7953700 mglB Escherichia coli BW2952 methyl-galactoside transporter subunit YP_002927128.1 2129855 R 595496 CDS YP_002927129.1 238901333 7954258 complement(2131133..2132173) 1 NC_012759.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2132173 galS 7954258 galS Escherichia coli BW2952 DNA-binding transcriptional regulator GalS YP_002927129.1 2131133 R 595496 CDS YP_002927130.1 238901334 7953453 complement(2132315..2133472) 1 NC_012759.1 MG1655 equivalent: b2152; hypothetical protein 2133472 yeiB 7953453 yeiB Escherichia coli BW2952 hypothetical protein YP_002927130.1 2132315 R 595496 CDS YP_002927131.1 238901335 7952675 complement(2133489..2134157) 1 NC_012759.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2134157 folE 7952675 folE Escherichia coli BW2952 GTP cyclohydrolase I YP_002927131.1 2133489 R 595496 CDS YP_002927132.1 238901336 7953874 2134415..2135251 1 NC_012759.1 MG1655 equivalent: b2154; putative esterase 2135251 yeiG 7953874 yeiG Escherichia coli BW2952 putative esterase YP_002927132.1 2134415 D 595496 CDS YP_002927133.1 238901337 7954863 complement(2135283..2137274) 1 NC_012759.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2137274 cirA 7954863 cirA Escherichia coli BW2952 colicin I receptor YP_002927133.1 2135283 R 595496 CDS YP_002927134.1 238901338 7953569 complement(2137568..2139037) 1 NC_012759.1 MG1655 equivalent: b2156; lysine transporter 2139037 lysP 7953569 lysP Escherichia coli BW2952 lysine transporter YP_002927134.1 2137568 R 595496 CDS YP_002927135.1 238901339 7954182 complement(2139242..2140123) 1 NC_012759.1 MG1655 equivalent: b2157; putative DNA-binding transcriptional regulator 2140123 yeiE 7954182 yeiE Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927135.1 2139242 R 595496 CDS YP_002927136.1 238901340 7954767 2140222..2141271 1 NC_012759.1 MG1655 equivalent: b2158; hypothetical protein 2141271 yeiH 7954767 yeiH Escherichia coli BW2952 hypothetical protein YP_002927136.1 2140222 D 595496 CDS YP_002927137.1 238901341 7952718 2141345..2142202 1 NC_012759.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2142202 nfo 7952718 nfo Escherichia coli BW2952 endonuclease IV YP_002927137.1 2141345 D 595496 CDS YP_002927138.1 238901342 7953517 2142205..2143293 1 NC_012759.1 MG1655 equivalent: b2160; hypothetical protein 2143293 yeiI 7953517 yeiI Escherichia coli BW2952 hypothetical protein YP_002927138.1 2142205 D 595496 CDS YP_002927139.1 238901343 7955095 complement(2143400..2144650) 1 NC_012759.1 MG1655 equivalent: b2161; putative nucleoside transporter 2144650 nupX 7955095 nupX Escherichia coli BW2952 putative nucleoside transporter YP_002927139.1 2143400 R 595496 CDS YP_002927140.1 238901344 7955183 complement(2144750..2145691) 1 NC_012759.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2145691 rihB 7955183 rihB Escherichia coli BW2952 ribonucleoside hydrolase 2 YP_002927140.1 2144750 R 595496 CDS YP_002927141.1 238901345 7955967 2145860..2146519 1 NC_012759.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2146519 yeiL 7955967 yeiL Escherichia coli BW2952 DNA-binding transcriptional activator YeiL YP_002927141.1 2145860 D 595496 CDS YP_002927142.1 238901346 7953393 complement(2146590..2147840) 1 NC_012759.1 MG1655 equivalent: b2164; putative nucleoside transporter 2147840 yeiM 7953393 yeiM Escherichia coli BW2952 putative nucleoside transporter YP_002927142.1 2146590 R 595496 CDS YP_002927143.1 238901347 7955184 complement(2147934..2148872) 1 NC_012759.1 MG1655 equivalent: b2165; hypothetical protein 2148872 yeiN 7955184 yeiN Escherichia coli BW2952 hypothetical protein YP_002927143.1 2147934 R 595496 CDS YP_002927144.1 238901348 7952829 complement(2148860..2149801) 1 NC_012759.1 MG1655 equivalent: b2166; hypothetical protein 2149801 yeiC 7952829 yeiC Escherichia coli BW2952 hypothetical protein YP_002927144.1 2148860 R 595496 CDS YP_002927145.1 238901349 7955093 complement(2150224..2151915) 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 2151915 fruA 7955093 fruA Escherichia coli BW2952 PTS system fructose-specific transporter subunit IIBC YP_002927145.1 2150224 R 595496 CDS YP_002927146.1 238901350 7953681 2151229..2151939 1 NC_012759.1 MG1655 equivalent: b2168; fructose-1-phosphate kinase 2151939 fruK 7953681 fruK Escherichia coli BW2952 fructose-1-phosphate kinase YP_002927146.1 2151229 D 595496 CDS YP_002927147.1 238901351 7956298 2152837..2153394 1 NC_012759.1 MG1655 equivalent: b2174; UDP pyrophosphate phosphatase 2153394 lpxT 7956298 lpxT Escherichia coli BW2952 UDP pyrophosphate phosphatase YP_002927147.1 2152837 D 595496 CDS YP_002927148.1 238901352 7956251 2153806..2154372 1 NC_012759.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 2154372 spr 7956251 spr Escherichia coli BW2952 putative outer membrane lipoprotein YP_002927148.1 2153806 D 595496 CDS YP_002927149.1 238901353 7955292 2154553..2156109 1 NC_012759.1 MG1655 equivalent: b2176; hypothetical protein 2156109 rtn 7955292 rtn Escherichia coli BW2952 hypothetical protein YP_002927149.1 2154553 D 595496 CDS YP_002927150.1 238901354 7952994 2156191..2158005 1 NC_012759.1 MG1655 equivalent: b2177; putative oligopeptide transporter subunit 2158005 yejA 7952994 yejA Escherichia coli BW2952 putative oligopeptide transporter subunit YP_002927150.1 2156191 D 595496 CDS YP_002927151.1 238901355 7955192 2158006..2159100 1 NC_012759.1 MG1655 equivalent: b2178; putative oligopeptide transporter subunit 2159100 yejB 7955192 yejB Escherichia coli BW2952 putative oligopeptide transporter subunit YP_002927151.1 2158006 D 595496 CDS YP_002927152.1 238901356 7955193 2159100..2160125 1 NC_012759.1 MG1655 equivalent: b2179; putative oligopeptide transporter subunit 2160125 yejE 7955193 yejE Escherichia coli BW2952 putative oligopeptide transporter subunit YP_002927152.1 2159100 D 595496 CDS YP_002927153.1 238901357 7955194 2160127..2161716 1 NC_012759.1 MG1655 equivalent: b2180; fused putative oligopeptide transporter subunits of ABC superfamilly: ATP-binding components 2161716 yejF 7955194 yejF Escherichia coli BW2952 fused putative oligopeptide transporter subunits of ABC superfamilly: ATP-binding components YP_002927153.1 2160127 D 595496 CDS YP_002927154.1 238901358 7953719 complement(2161720..2162064) 1 NC_012759.1 MG1655 equivalent: b2181; hypothetical protein 2162064 yejG 7953719 yejG Escherichia coli BW2952 hypothetical protein YP_002927154.1 2161720 R 595496 CDS YP_002927155.1 238901359 7955383 complement(2162397..2163587) 1 NC_012759.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 2163587 bcr 7955383 bcr Escherichia coli BW2952 bicyclomycin/multidrug efflux system protein YP_002927155.1 2162397 R 595496 CDS YP_002927156.1 238901360 7952554 complement(2163615..2164310) 1 NC_012759.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2164310 rsuA 7952554 rsuA Escherichia coli BW2952 16S rRNA pseudouridylate synthase A YP_002927156.1 2163615 R 595496 CDS YP_002927157.1 238901361 7952225 2164459..2166219 1 NC_012759.1 MG1655 equivalent: b2184; ATP-dependent helicase 2166219 yejH 7952225 yejH Escherichia coli BW2952 ATP-dependent helicase YP_002927157.1 2164459 D 595496 CDS YP_002927158.1 238901362 7954665 2166344..2166628 1 NC_012759.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2166628 rplY 7954665 rplY Escherichia coli BW2952 50S ribosomal protein L25 YP_002927158.1 2166344 D 595496 CDS YP_002927159.1 238901363 7952353 complement(2166767..2167774) 1 NC_012759.1 MG1655 equivalent: b2186; nucleoid-associated protein NdpA 2167774 yejK 7952353 yejK Escherichia coli BW2952 nucleoid-associated protein NdpA YP_002927159.1 2166767 R 595496 CDS YP_002927160.1 238901364 7954414 2167956..2168183 1 NC_012759.1 MG1655 equivalent: b2187; hypothetical protein 2168183 yejL 7954414 yejL Escherichia coli BW2952 hypothetical protein YP_002927160.1 2167956 D 595496 CDS YP_002927161.1 238901365 7952995 2168203..2169963 1 NC_012759.1 MG1655 equivalent: b2188; putative hydrolase, inner membrane 2169963 yejM 7952995 yejM Escherichia coli BW2952 putative hydrolase, inner membrane YP_002927161.1 2168203 D 595496 CDS YP_002927162.1 238901366 7952135 complement(2172892..2173908) 1 NC_012759.1 MG1655 equivalent: b2192; IS5 transposase and trans-activator 2173908 insH 7952135 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002927162.1 2172892 R 595496 CDS YP_002927163.1 238901367 7954042 2174327..2174974 1 NC_012759.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2174974 narP 7954042 narP Escherichia coli BW2952 transcriptional regulator NarP YP_002927163.1 2174327 D 595496 CDS YP_002927164.1 238901368 7953355 complement(2175185..2176237) 1 NC_012759.1 MG1655 equivalent: b2194; heme lyase, CcmH subunit 2176237 ccmH 7953355 ccmH Escherichia coli BW2952 heme lyase, CcmH subunit YP_002927164.1 2175185 R 595496 CDS YP_002927165.1 238901369 7953903 complement(2176234..2176791) 1 NC_012759.1 MG1655 equivalent: b2195; periplasmic thioredoxin of cytochrome c-type biogenesis 2176791 ccmG 7953903 ccmG Escherichia coli BW2952 periplasmic thioredoxin of cytochrome c-type biogenesis YP_002927165.1 2176234 R 595496 CDS YP_002927166.1 238901370 7954501 complement(2176788..2178731) 1 NC_012759.1 MG1655 equivalent: b2196; heme lyase, CcmF subunit 2178731 ccmF 7954501 ccmF Escherichia coli BW2952 heme lyase, CcmF subunit YP_002927166.1 2176788 R 595496 CDS YP_002927167.1 238901371 7953902 complement(2178728..2179207) 1 NC_012759.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2179207 ccmE 7953902 ccmE Escherichia coli BW2952 cytochrome c-type biogenesis protein CcmE YP_002927167.1 2178728 R 595496 CDS YP_002927168.1 238901372 7954492 complement(2179204..2179413) 1 NC_012759.1 MG1655 equivalent: b2198; cytochrome c biogenesis protein 2179413 ccmD 7954492 ccmD Escherichia coli BW2952 cytochrome c biogenesis protein YP_002927168.1 2179204 R 595496 CDS YP_002927169.1 238901373 7953193 complement(2179410..2180147) 1 NC_012759.1 MG1655 equivalent: b2199; heme exporter subunit 2180147 ccmC 7953193 ccmC Escherichia coli BW2952 heme exporter subunit YP_002927169.1 2179410 R 595496 CDS YP_002927170.1 238901374 7953896 complement(2180189..2180851) 1 NC_012759.1 MG1655 equivalent: b2200; heme exporter subunit 2180851 ccmB 7953896 ccmB Escherichia coli BW2952 heme exporter subunit YP_002927170.1 2180189 R 595496 CDS YP_002927171.1 238901375 7953897 complement(2180848..2181471) 1 NC_012759.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2181471 ccmA 7953897 ccmA Escherichia coli BW2952 cytochrome c biogenesis protein CcmA YP_002927171.1 2180848 R 595496 CDS YP_002927172.1 238901376 7953898 complement(2181484..2182086) 1 NC_012759.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2182086 napC 7953898 napC Escherichia coli BW2952 cytochrome c-type protein NapC YP_002927172.1 2181484 R 595496 CDS YP_002927173.1 238901377 7954394 complement(2182096..2182545) 1 NC_012759.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2182545 napB 7954394 napB Escherichia coli BW2952 citrate reductase cytochrome c-type subunit YP_002927173.1 2182096 R 595496 CDS YP_002927174.1 238901378 7954396 complement(2182542..2183405) 1 NC_012759.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2183405 napH 7954396 napH Escherichia coli BW2952 quinol dehydrogenase membrane component YP_002927174.1 2182542 R 595496 CDS YP_002927175.1 238901379 7953565 complement(2183392..2184087) 1 NC_012759.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2184087 napG 7953565 napG Escherichia coli BW2952 quinol dehydrogenase periplasmic component YP_002927175.1 2183392 R 595496 CDS YP_002927176.1 238901380 7953566 complement(2184094..2186580) 1 NC_012759.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2186580 napA 7953566 napA Escherichia coli BW2952 nitrate reductase catalytic subunit YP_002927176.1 2184094 R 595496 CDS YP_002927177.1 238901381 7954395 complement(2186577..2186840) 1 NC_012759.1 MG1655 equivalent: b2207; assembly protein for periplasmic nitrate reductase 2186840 napD 7954395 napD Escherichia coli BW2952 assembly protein for periplasmic nitrate reductase YP_002927177.1 2186577 R 595496 CDS YP_002927178.1 238901382 7952519 complement(2186830..2187324) 1 NC_012759.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 2187324 napF 7952519 napF Escherichia coli BW2952 ferredoxin-type protein YP_002927178.1 2186830 R 595496 CDS YP_002927179.1 238901383 7953567 2187433..2187597 1 NC_012759.1 MG1655 equivalent: b4604; hypothetical protein 2187597 yojO 7953567 yojO Escherichia coli BW2952 hypothetical protein YP_002927179.1 2187433 D 595496 CDS YP_002927180.1 238901384 7953981 2187732..2188220 1 NC_012759.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2188220 eco 7953981 eco Escherichia coli BW2952 ecotin YP_002927180.1 2187732 D 595496 CDS YP_002927181.1 238901385 7953513 complement(2188935..2190581) 1 NC_012759.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2190581 mqo 7953513 mqo Escherichia coli BW2952 malate:quinone oxidoreductase YP_002927181.1 2188935 R 595496 CDS YP_002927182.1 238901386 7954198 complement(2190799..2192442) 1 NC_012759.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component 2192442 yojI 7954198 yojI Escherichia coli BW2952 multidrug transporter membrane protein/ATP-binding component YP_002927182.1 2190799 R 595496 CDS YP_002927183.1 238901387 7953715 complement(2192518..2193168) 1 NC_012759.1 MG1655 equivalent: b2212; oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions 2193168 alkB 7953715 alkB Escherichia coli BW2952 oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions YP_002927183.1 2192518 R 595496 CDS YP_002927184.1 238901388 7954455 complement(2193168..2194232) 1 NC_012759.1 MG1655 equivalent: b2213; fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 2194232 ada 7954455 ada Escherichia coli BW2952 fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase YP_002927184.1 2193168 R 595496 CDS YP_002927185.1 238901389 7953675 complement(2194306..2195361) 1 NC_012759.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2195361 apbE 7953675 apbE Escherichia coli BW2952 thiamine biosynthesis lipoprotein ApbE YP_002927185.1 2194306 R 595496 CDS YP_002927186.1 238901390 7955619 complement(2195473..2196576) 1 NC_012759.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2196576 ompC 7955619 ompC Escherichia coli BW2952 outer membrane porin protein C YP_002927186.1 2195473 R 595496 CDS YP_002927187.1 238901391 7952186 2197315..2199987 1 NC_012759.1 MG1655 equivalent: b2216; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2199987 rcsD 7952186 rcsD Escherichia coli BW2952 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_002927187.1 2197315 D 595496 CDS YP_002927188.1 238901392 7954555 2200004..2200654 1 NC_012759.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2200654 rcsB 7954555 rcsB Escherichia coli BW2952 transcriptional regulator RcsB YP_002927188.1 2200004 D 595496 CDS YP_002927189.1 238901393 7953360 complement(2200854..2203703) 1 NC_012759.1 MG1655 equivalent: b2218; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2203703 rcsC 7953360 rcsC Escherichia coli BW2952 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_002927189.1 2200854 R 595496 CDS YP_002927190.1 238901394 7953932 2203870..2205696 1 NC_012759.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2205696 atoS 7953932 atoS Escherichia coli BW2952 sensory histidine kinase AtoS YP_002927190.1 2203870 D 595496 CDS YP_002927191.1 238901395 7956011 2205693..2207078 1 NC_012759.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2207078 atoC 7956011 atoC Escherichia coli BW2952 acetoacetate metabolism regulatory protein AtoC YP_002927191.1 2205693 D 595496 CDS YP_002927192.1 238901396 7953738 2207274..2207936 1 NC_012759.1 MG1655 equivalent: b2221; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2207936 atoD 7953738 atoD Escherichia coli BW2952 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_002927192.1 2207274 D 595496 CDS YP_002927193.1 238901397 7952403 2207936..2208586 1 NC_012759.1 MG1655 equivalent: b2222; acetyl-CoA:acetoacetyl-CoA transferase, beta subunit 2208586 atoA 7952403 atoA Escherichia coli BW2952 acetyl-CoA:acetoacetyl-CoA transferase, beta subunit YP_002927193.1 2207936 D 595496 CDS YP_002927194.1 238901398 7952404 2208583..2209905 1 NC_012759.1 MG1655 equivalent: b2223; short chain fatty acid transporter 2209905 atoE 7952404 atoE Escherichia coli BW2952 short chain fatty acid transporter YP_002927194.1 2208583 D 595496 CDS YP_002927195.1 238901399 7956041 2209936..2211120 1 NC_012759.1 MG1655 equivalent: b2224; acetyl-CoA acetyltransferase 2211120 atoB 7956041 atoB Escherichia coli BW2952 acetyl-CoA acetyltransferase YP_002927195.1 2209936 D 595496 CDS YP_002927196.1 238901400 7952398 complement(2211194..2211970) 1 NC_012759.1 MG1655 equivalent: b2225; hypothetical protein 2211970 yfaP 7952398 yfaP Escherichia coli BW2952 hypothetical protein YP_002927196.1 2211194 R 595496 CDS YP_002927197.1 238901401 7952830 complement(2211975..2213624) 1 NC_012759.1 MG1655 equivalent: b2226; hypothetical protein 2213624 yfaQ 7952830 yfaQ Escherichia coli BW2952 hypothetical protein YP_002927197.1 2211975 R 595496 CDS YP_002927198.1 238901402 7955384 complement(2218163..2218786) 1 NC_012759.1 MG1655 equivalent: b2229; hypothetical protein 2218786 yfaT 7955384 yfaT Escherichia coli BW2952 hypothetical protein YP_002927198.1 2218163 R 595496 CDS YP_002927199.1 238901403 7955385 complement(2218783..2220471) 1 NC_012759.1 MG1655 equivalent: b2230; hypothetical protein 2220471 yfaA 7955385 yfaA Escherichia coli BW2952 hypothetical protein YP_002927199.1 2218783 R 595496 CDS YP_002927200.1 238901404 7955386 complement(2220620..2223247) 1 NC_012759.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2223247 gyrA 7955386 gyrA Escherichia coli BW2952 DNA gyrase subunit A YP_002927200.1 2220620 R 595496 CDS YP_002927201.1 238901405 7953306 2223394..2224116 1 NC_012759.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2224116 ubiG 7953306 ubiG Escherichia coli BW2952 3-demethylubiquinone-9 3-methyltransferase YP_002927201.1 2223394 D 595496 CDS YP_002927202.1 238901406 7952558 complement(2224244..2227996) 1 NC_012759.1 MG1655 equivalent: b2233; adhesin 2227996 yfaL 7952558 yfaL Escherichia coli BW2952 adhesin YP_002927202.1 2224244 R 595496 CDS YP_002927203.1 238901407 7952426 complement(2228421..2228564) 1 NC_012759.1 MG1655 equivalent: b4605; hypothetical protein 2228564 ypaB 7952426 ypaB Escherichia coli BW2952 hypothetical protein YP_002927203.1 2228421 R 595496 CDS YP_002927204.1 238901408 7953968 2228692..2230977 1 NC_012759.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2230977 nrdA 7953968 nrdA Escherichia coli BW2952 ribonucleotide-diphosphate reductase subunit alpha YP_002927204.1 2228692 D 595496 CDS YP_002927205.1 238901409 7955964 2231211..2232341 1 NC_012759.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2232341 nrdB 7955964 nrdB Escherichia coli BW2952 ribonucleotide-diphosphate reductase subunit beta YP_002927205.1 2231211 D 595496 CDS YP_002927206.1 238901410 7955965 2232341..2232595 1 NC_012759.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2232595 yfaE 7955965 yfaE Escherichia coli BW2952 2Fe-2S ferredoxin YP_002927206.1 2232341 D 595496 CDS YP_002927207.1 238901411 7954586 complement(2232649..2233299) 1 NC_012759.1 MG1655 equivalent: b2237; hypothetical protein 2233299 inaA 7954586 inaA Escherichia coli BW2952 hypothetical protein YP_002927207.1 2232649 R 595496 CDS YP_002927208.1 238901412 7952831 complement(2233762..2234838) 1 NC_012759.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2234838 glpQ 7952831 glpQ Escherichia coli BW2952 glycerophosphodiester phosphodiesterase YP_002927208.1 2233762 R 595496 CDS YP_002927209.1 238901413 7954491 complement(2234843..2236201) 1 NC_012759.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2236201 glpT 7954491 glpT Escherichia coli BW2952 sn-glycerol-3-phosphate transporter YP_002927209.1 2234843 R 595496 CDS YP_002927210.1 238901414 7956054 2236474..2238102 1 NC_012759.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2238102 glpA 7956054 glpA Escherichia coli BW2952 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002927210.1 2236474 D 595496 CDS YP_002927211.1 238901415 7956050 2238092..2239351 1 NC_012759.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2239351 glpB 7956050 glpB Escherichia coli BW2952 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002927211.1 2238092 D 595496 CDS YP_002927212.1 238901416 7956051 2239348..2240538 1 NC_012759.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2240538 glpC 7956051 glpC Escherichia coli BW2952 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002927212.1 2239348 D 595496 CDS YP_002927213.1 238901417 7956052 2240731..2241630 1 NC_012759.1 MG1655 equivalent: b2244; hypothetical protein 2241630 yfaD 7956052 yfaD Escherichia coli BW2952 hypothetical protein YP_002927213.1 2240731 D 595496 CDS YP_002927214.1 238901418 7952996 2241643..2241828 1 NC_012759.1 MG1655 equivalent: b4543; hypothetical protein 2241828 ypaA 7952996 ypaA Escherichia coli BW2952 hypothetical protein YP_002927214.1 2241643 D 595496 CDS YP_002927215.1 238901419 7955534 complement(2241869..2242672) 1 NC_012759.1 MG1655 equivalent: b2245; putative aldolase 2242672 yfaU 7955534 yfaU Escherichia coli BW2952 putative aldolase YP_002927215.1 2241869 R 595496 CDS YP_002927216.1 238901420 7954583 complement(2242690..2243979) 1 NC_012759.1 MG1655 equivalent: b2246; putative transporter 2243979 yfaV 7954583 yfaV Escherichia coli BW2952 putative transporter YP_002927216.1 2242690 R 595496 CDS YP_002927217.1 238901421 7955659 complement(2244036..2245253) 1 NC_012759.1 MG1655 equivalent: b2247; putative enolase 2245253 yfaW 7955659 yfaW Escherichia coli BW2952 putative enolase YP_002927217.1 2244036 R 595496 CDS YP_002927218.1 238901422 7954837 complement(2245256..2246038) 1 NC_012759.1 MG1655 equivalent: b2248; putative DNA-binding transcriptional regulator 2246038 yfaX 7954837 yfaX Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927218.1 2245256 R 595496 CDS YP_002927219.1 238901423 7954768 complement(2246258..2247460) 1 NC_012759.1 MG1655 equivalent: b2249; competence damage-inducible protein A 2247460 yfaY 7954768 yfaY Escherichia coli BW2952 competence damage-inducible protein A YP_002927219.1 2246258 R 595496 CDS YP_002927220.1 238901424 7952832 complement(2247560..2248102) 1 NC_012759.1 MG1655 equivalent: b2250; putative outer membrane porin protein 2248102 yfaZ 7952832 yfaZ Escherichia coli BW2952 putative outer membrane porin protein YP_002927220.1 2247560 R 595496 CDS YP_002927221.1 238901425 7955209 2248381..2248806 1 NC_012759.1 MG1655 equivalent: b2251; putative NUDIX hydrolase 2248806 nudI 7955209 nudI Escherichia coli BW2952 putative NUDIX hydrolase YP_002927221.1 2248381 D 595496 CDS YP_002927222.1 238901426 7955191 complement(2248845..2249447) 1 NC_012759.1 MG1655 equivalent: b2252; hypothetical protein 2249447 ais 7955191 ais Escherichia coli BW2952 hypothetical protein YP_002927222.1 2248845 R 595496 CDS YP_002927223.1 238901427 7952833 2249755..2250894 1 NC_012759.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2250894 arnB 7952833 arnB Escherichia coli BW2952 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_002927223.1 2249755 D 595496 CDS YP_002927224.1 238901428 7956261 2250898..2251866 1 NC_012759.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; UDP phosphate 4-deoxy-4-formamido-L-arabinose transferase 2251866 arnC 7956261 arnC Escherichia coli BW2952 UDP phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_002927224.1 2250898 D 595496 CDS YP_002927225.1 238901429 7956247 2251866..2253848 1 NC_012759.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2253848 arnA 7956247 arnA Escherichia coli BW2952 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_002927225.1 2251866 D 595496 CDS YP_002927226.1 238901430 7953751 2253845..2254735 1 NC_012759.1 MG1655 equivalent: b2256; hypothetical protein 2254735 arnD 7953751 arnD Escherichia coli BW2952 hypothetical protein YP_002927226.1 2253845 D 595496 CDS YP_002927227.1 238901431 7952997 2254735..2256387 1 NC_012759.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2256387 arnT 7952997 arnT Escherichia coli BW2952 4-amino-4-deoxy-L-arabinose transferase YP_002927227.1 2254735 D 595496 CDS YP_002927228.1 238901432 7952329 2256384..2256719 1 NC_012759.1 MG1655 equivalent: b4544; hypothetical protein 2256719 arnE 7952329 arnE Escherichia coli BW2952 hypothetical protein YP_002927228.1 2256384 D 595496 CDS YP_002927229.1 238901433 7953074 2256719..2257105 1 NC_012759.1 MG1655 equivalent: b2258; hypothetical protein 2257105 arnF 7953074 arnF Escherichia coli BW2952 hypothetical protein YP_002927229.1 2256719 D 595496 CDS YP_002927230.1 238901434 7955051 complement(2257099..2257365) 1 NC_012759.1 MG1655 equivalent: b2259; polymyxin resistance protein B 2257365 pmrD 7955051 pmrD Escherichia coli BW2952 polymyxin resistance protein B YP_002927230.1 2257099 R 595496 CDS YP_002927231.1 238901435 7954567 complement(2257475..2258830) 1 NC_012759.1 MG1655 equivalent: b2260; O-succinylbenzoic acid--CoA ligase 2258830 menE 7954567 menE Escherichia coli BW2952 O-succinylbenzoic acid--CoA ligase YP_002927231.1 2257475 R 595496 CDS YP_002927232.1 238901436 7954435 complement(2258827..2259789) 1 NC_012759.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2259789 menC 7954435 menC Escherichia coli BW2952 O-succinylbenzoate synthase YP_002927232.1 2258827 R 595496 CDS YP_002927233.1 238901437 7954436 complement(2259789..2260646) 1 NC_012759.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2260646 menB 7954436 menB Escherichia coli BW2952 naphthoate synthase YP_002927233.1 2259789 R 595496 CDS YP_002927234.1 238901438 7953260 complement(2260661..2261419) 1 NC_012759.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 2261419 yfbB 7953260 yfbB Escherichia coli BW2952 acyl-CoA thioester hydrolase YfbB YP_002927234.1 2260661 R 595496 CDS YP_002927235.1 238901439 7955274 complement(2261416..2263086) 1 NC_012759.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2263086 menD 7955274 menD Escherichia coli BW2952 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002927235.1 2261416 R 595496 CDS YP_002927236.1 238901440 7952557 complement(2263175..2264470) 1 NC_012759.1 MG1655 equivalent: b2265; isochorismate synthase 2 2264470 menF 7952557 menF Escherichia coli BW2952 isochorismate synthase 2 YP_002927236.1 2263175 R 595496 CDS YP_002927237.1 238901441 7954050 complement(2264549..2264854) 1 NC_012759.1 MG1655 equivalent: b2266; hypothetical protein 2264854 elaB 7954050 elaB Escherichia coli BW2952 hypothetical protein YP_002927237.1 2264549 R 595496 CDS YP_002927238.1 238901442 7952834 complement(2264909..2265370) 1 NC_012759.1 MG1655 equivalent: b2267; hypothetical protein 2265370 elaA 7952834 elaA Escherichia coli BW2952 hypothetical protein YP_002927238.1 2264909 R 595496 CDS YP_002927239.1 238901443 7954616 2265435..2266352 1 NC_012759.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2266352 rbn 7954616 rbn Escherichia coli BW2952 ribonuclease Z YP_002927239.1 2265435 D 595496 CDS YP_002927240.1 238901444 7952576 2266540..2267751 1 NC_012759.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2267751 elaD 7952576 elaD Escherichia coli BW2952 deubiquitinase YP_002927240.1 2266540 D 595496 CDS YP_002927241.1 238901445 7954845 complement(2267822..2269549) 1 NC_012759.1 MG1655 equivalent: b2270; hypothetical protein 2269549 yfbK 7954845 yfbK Escherichia coli BW2952 hypothetical protein YP_002927241.1 2267822 R 595496 CDS YP_002927242.1 238901446 7952835 2269687..2270658 1 NC_012759.1 MG1655 equivalent: b2271; putative peptidase 2270658 yfbL 7952835 yfbL Escherichia coli BW2952 putative peptidase YP_002927242.1 2269687 D 595496 CDS YP_002927243.1 238901447 7955282 2270761..2271264 1 NC_012759.1 MG1655 equivalent: b2272; hypothetical protein 2271264 yfbM 7955282 yfbM Escherichia coli BW2952 hypothetical protein YP_002927243.1 2270761 D 595496 CDS YP_002927244.1 238901448 7955493 complement(2271537..2272253) 1 NC_012759.1 MG1655 equivalent: b2273; hypothetical protein 2272253 yfbN 7955493 yfbN Escherichia coli BW2952 hypothetical protein YP_002927244.1 2271537 R 595496 CDS YP_002927245.1 238901449 7955387 2272408..2272884 1 NC_012759.1 MG1655 equivalent: b2274; hypothetical protein 2272884 yfbO 7955387 yfbO Escherichia coli BW2952 hypothetical protein YP_002927245.1 2272408 D 595496 CDS YP_002927246.1 238901450 7955494 2272940..2273791 1 NC_012759.1 MG1655 equivalent: b2275; hypothetical protein 2273791 yfbP 7955494 yfbP Escherichia coli BW2952 hypothetical protein YP_002927246.1 2272940 D 595496 CDS YP_002927247.1 238901451 7955495 complement(2273875..2275332) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2275332 nuoN 7955495 nuoN Escherichia coli BW2952 NADH dehydrogenase subunit N YP_002927247.1 2273875 R 595496 CDS YP_002927248.1 238901452 7954368 complement(2275339..2276868) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2276868 nuoM 7954368 nuoM Escherichia coli BW2952 NADH dehydrogenase subunit M YP_002927248.1 2275339 R 595496 CDS YP_002927249.1 238901453 7954367 complement(2277032..2278873) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2278873 nuoL 7954367 nuoL Escherichia coli BW2952 NADH dehydrogenase subunit L YP_002927249.1 2277032 R 595496 CDS YP_002927250.1 238901454 7954366 complement(2278870..2279172) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2279172 nuoK 7954366 nuoK Escherichia coli BW2952 NADH dehydrogenase subunit K YP_002927250.1 2278870 R 595496 CDS YP_002927251.1 238901455 7954365 complement(2279169..2279723) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2279723 nuoJ 7954365 nuoJ Escherichia coli BW2952 NADH dehydrogenase subunit J YP_002927251.1 2279169 R 595496 CDS YP_002927252.1 238901456 7954364 complement(2279735..2280277) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2280277 nuoI 7954364 nuoI Escherichia coli BW2952 NADH dehydrogenase subunit I YP_002927252.1 2279735 R 595496 CDS YP_002927253.1 238901457 7954361 complement(2280292..2281269) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2281269 nuoH 7954361 nuoH Escherichia coli BW2952 NADH dehydrogenase subunit H YP_002927253.1 2280292 R 595496 CDS YP_002927254.1 238901458 7954363 complement(2281266..2283992) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2283992 nuoG 7954363 nuoG Escherichia coli BW2952 NADH dehydrogenase subunit G YP_002927254.1 2281266 R 595496 CDS YP_002927255.1 238901459 7954360 complement(2284045..2285382) 1 NC_012759.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2285382 nuoF 7954360 nuoF Escherichia coli BW2952 NADH dehydrogenase I subunit F YP_002927255.1 2284045 R 595496 CDS YP_002927256.1 238901460 7954359 complement(2285379..2285879) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2285879 nuoE 7954359 nuoE Escherichia coli BW2952 NADH dehydrogenase subunit E YP_002927256.1 2285379 R 595496 CDS YP_002927257.1 238901461 7954358 complement(2285882..2287672) 1 NC_012759.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2287672 nuoC 7954358 nuoC Escherichia coli BW2952 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_002927257.1 2285882 R 595496 CDS YP_002927258.1 238901462 7954357 complement(2287778..2288440) 1 NC_012759.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2288440 nuoB 7954357 nuoB Escherichia coli BW2952 NADH dehydrogenase subunit B YP_002927258.1 2287778 R 595496 CDS YP_002927259.1 238901463 7954356 complement(2288456..2288899) 1 NC_012759.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2288899 nuoA 7954356 nuoA Escherichia coli BW2952 NADH dehydrogenase subunit A YP_002927259.1 2288456 R 595496 CDS YP_002927260.1 238901464 7954362 complement(2289530..2290468) 1 NC_012759.1 MG1655 equivalent: b2289; DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes 2290468 lrhA 7954362 lrhA Escherichia coli BW2952 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes YP_002927260.1 2289530 R 595496 CDS YP_002927261.1 238901465 7953472 2291388..2292605 1 NC_012759.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2292605 yfbQ 7953472 yfbQ Escherichia coli BW2952 aminotransferase AlaT YP_002927261.1 2291388 D 595496 CDS YP_002927262.1 238901466 7954647 2292689..2293288 1 NC_012759.1 MG1655 equivalent: b2291; hypothetical protein 2293288 yfbR 7954647 yfbR Escherichia coli BW2952 hypothetical protein YP_002927262.1 2292689 D 595496 CDS YP_002927263.1 238901467 7953236 complement(2293347..2295179) 1 NC_012759.1 MG1655 equivalent: b2292; putative transporter 2295179 yfbS 7953236 yfbS Escherichia coli BW2952 putative transporter YP_002927263.1 2293347 R 595496 CDS YP_002927264.1 238901468 7955660 complement(2295266..2295916) 1 NC_012759.1 MG1655 equivalent: b2293; putative phosphatase 2295916 yfbT 7955660 yfbT Escherichia coli BW2952 putative phosphatase YP_002927264.1 2295266 R 595496 CDS YP_002927265.1 238901469 7954976 complement(2295927..2296421) 1 NC_012759.1 MG1655 equivalent: b2294; hypothetical protein 2296421 yfbU 7954976 yfbU Escherichia coli BW2952 hypothetical protein YP_002927265.1 2295927 R 595496 CDS YP_002927266.1 238901470 7952836 complement(2296504..2296959) 1 NC_012759.1 MG1655 equivalent: b2295; hypothetical protein 2296959 yfbV 7952836 yfbV Escherichia coli BW2952 hypothetical protein YP_002927266.1 2296504 R 595496 CDS YP_002927267.1 238901471 7952676 2297297..2298499 1 NC_012759.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2298499 ackA 7952676 ackA Escherichia coli BW2952 acetate kinase YP_002927267.1 2297297 D 595496 CDS YP_002927268.1 238901472 7952388 2298574..2300718 1 NC_012759.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2300718 pta 7952388 pta Escherichia coli BW2952 phosphate acetyltransferase YP_002927268.1 2298574 D 595496 CDS YP_002927269.1 238901473 7954513 2300908..2302428 1 NC_012759.1 MG1655 equivalent: b2298; hypothetical protein 2302428 yfcC 7954513 yfcC Escherichia coli BW2952 hypothetical protein YP_002927269.1 2300908 D 595496 CDS YP_002927270.1 238901474 7955052 complement(2302461..2303003) 1 NC_012759.1 MG1655 equivalent: b2299; putative NUDIX hydrolase 2303003 yfcD 7955052 yfcD Escherichia coli BW2952 putative NUDIX hydrolase YP_002927270.1 2302461 R 595496 CDS YP_002927271.1 238901475 7955188 complement(2303061..2303615) 1 NC_012759.1 MG1655 equivalent: b2300; phosphodiesterase 2303615 yfcE 7955188 yfcE Escherichia coli BW2952 phosphodiesterase YP_002927271.1 2303061 R 595496 CDS YP_002927272.1 238901476 7955311 complement(2303668..2304312) 1 NC_012759.1 MG1655 equivalent: b2301; putative enzyme 2304312 yfcF 7955311 yfcF Escherichia coli BW2952 putative enzyme YP_002927272.1 2303668 R 595496 CDS YP_002927273.1 238901477 7954841 2304448..2305095 1 NC_012759.1 MG1655 equivalent: b2302; glutathione S-transferase 2305095 yfcG 7954841 yfcG Escherichia coli BW2952 glutathione S-transferase YP_002927273.1 2304448 D 595496 CDS YP_002927274.1 238901478 7954928 2305152..2305514 1 NC_012759.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2305514 folX 7954928 folX Escherichia coli BW2952 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_002927274.1 2305152 D 595496 CDS YP_002927275.1 238901479 7953239 2305535..2306428 1 NC_012759.1 MG1655 equivalent: b2304; hypothetical protein 2306428 yfcH 7953239 yfcH Escherichia coli BW2952 hypothetical protein YP_002927275.1 2305535 D 595496 CDS YP_002927276.1 238901480 7953082 complement(2306476..2307366) 1 NC_012759.1 MG1655 equivalent: b2305; hypothetical protein 2307366 yfcI 7953082 yfcI Escherichia coli BW2952 hypothetical protein YP_002927276.1 2306476 R 595496 CDS YP_002927277.1 238901481 7952837 complement(2307563..2308336) 1 NC_012759.1 MG1655 equivalent: b2306; histidine/lysine/arginine/ornithine transporter subunit 2308336 hisP 7952837 hisP Escherichia coli BW2952 histidine/lysine/arginine/ornithine transporter subunit YP_002927277.1 2307563 R 595496 CDS YP_002927278.1 238901482 7953909 complement(2308344..2309060) 1 NC_012759.1 MG1655 equivalent: b2307; histidine/lysine/arginine/ornithine transporter subunit 2309060 hisM 7953909 hisM Escherichia coli BW2952 histidine/lysine/arginine/ornithine transporter subunit YP_002927278.1 2308344 R 595496 CDS YP_002927279.1 238901483 7953910 complement(2309057..2309743) 1 NC_012759.1 MG1655 equivalent: b2308; histidine/lysine/arginine/ornithine transporter subunit 2309743 hisQ 7953910 hisQ Escherichia coli BW2952 histidine/lysine/arginine/ornithine transporter subunit YP_002927279.1 2309057 R 595496 CDS YP_002927280.1 238901484 7953911 complement(2309833..2310615) 1 NC_012759.1 MG1655 equivalent: b2309; histidine/lysine/arginine/ornithine transporter subunit 2310615 hisJ 7953911 hisJ Escherichia coli BW2952 histidine/lysine/arginine/ornithine transporter subunit YP_002927280.1 2309833 R 595496 CDS YP_002927281.1 238901485 7953912 complement(2310836..2311618) 1 NC_012759.1 MG1655 equivalent: b2310; lysine/arginine/ornithine transporter subunit 2311618 argT 7953912 argT Escherichia coli BW2952 lysine/arginine/ornithine transporter subunit YP_002927281.1 2310836 R 595496 CDS YP_002927282.1 238901486 7954185 complement(2311884..2312453) 1 NC_012759.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2312453 ubiX 7954185 ubiX Escherichia coli BW2952 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002927282.1 2311884 R 595496 CDS YP_002927283.1 238901487 7952315 complement(2312548..2314065) 1 NC_012759.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2314065 purF 7952315 purF Escherichia coli BW2952 amidophosphoribosyltransferase YP_002927283.1 2312548 R 595496 CDS YP_002927284.1 238901488 7952463 complement(2314102..2314590) 1 NC_012759.1 membrane protein required for colicin V production; colicin V production protein 2314590 cvpA 7952463 cvpA Escherichia coli BW2952 colicin V production protein YP_002927284.1 2314102 R 595496 CDS YP_002927285.1 238901489 7954231 complement(2314849..2315511) 1 NC_012759.1 MG1655 equivalent: b2314; hypothetical protein 2315511 dedD 7954231 dedD Escherichia coli BW2952 hypothetical protein YP_002927285.1 2314849 R 595496 CDS YP_002927286.1 238901490 7952838 complement(2315501..2316769) 1 NC_012759.1 MG1655 equivalent: b2315; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2316769 folC 7952838 folC Escherichia coli BW2952 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_002927286.1 2315501 R 595496 CDS YP_002927287.1 238901491 7952567 complement(2316839..2317753) 1 NC_012759.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2317753 accD 7952567 accD Escherichia coli BW2952 acetyl-CoA carboxylase subunit beta YP_002927287.1 2316839 R 595496 CDS YP_002927288.1 238901492 7952399 complement(2317909..2318568) 1 NC_012759.1 MG1655 equivalent: b2317; hypothetical protein 2318568 dedA 7952399 dedA Escherichia coli BW2952 hypothetical protein YP_002927288.1 2317909 R 595496 CDS YP_002927289.1 238901493 7952677 complement(2318651..2319463) 1 NC_012759.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2319463 truA 7952677 truA Escherichia coli BW2952 tRNA pseudouridine synthase A YP_002927289.1 2318651 R 595496 CDS YP_002927290.1 238901494 7955821 complement(2319463..2320476) 1 NC_012759.1 MG1655 equivalent: b2319; putative semialdehyde dehydrogenase 2320476 usg 7955821 usg Escherichia coli BW2952 putative semialdehyde dehydrogenase YP_002927290.1 2319463 R 595496 CDS YP_002927291.1 238901495 7955585 complement(2320542..2321678) 1 NC_012759.1 MG1655 equivalent: b2320; erythronate-4-phosphate dehydrogenase 2321678 pdxB 7955585 pdxB Escherichia coli BW2952 erythronate-4-phosphate dehydrogenase YP_002927291.1 2320542 R 595496 CDS YP_002927292.1 238901496 7953531 2321777..2322772 1 NC_012759.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2322772 flk 7953531 flk Escherichia coli BW2952 flagella biosynthesis regulator YP_002927292.1 2321777 D 595496 CDS YP_002927293.1 238901497 7954902 complement(2322769..2323947) 1 NC_012759.1 MG1655 equivalent: b2322; hypothetical protein 2323947 yfcJ 7954902 yfcJ Escherichia coli BW2952 hypothetical protein YP_002927293.1 2322769 R 595496 CDS YP_002927294.1 238901498 7955661 complement(2324212..2325432) 1 NC_012759.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2325432 fabB 7955661 fabB Escherichia coli BW2952 3-oxoacyl-ACP synthase YP_002927294.1 2324212 R 595496 CDS YP_002927295.1 238901499 7952318 2325591..2327597 1 NC_012759.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2327597 mnmC 7952318 mnmC Escherichia coli BW2952 5-methylaminomethyl-2-thiouridine methyltransferase YP_002927295.1 2325591 D 595496 CDS YP_002927296.1 238901500 7953652 complement(2327718..2327996) 1 NC_012759.1 MG1655 equivalent: b2325; hypothetical protein 2327996 yfcL 7953652 yfcL Escherichia coli BW2952 hypothetical protein YP_002927296.1 2327718 R 595496 CDS YP_002927297.1 238901501 7955388 complement(2328030..2328578) 1 NC_012759.1 MG1655 equivalent: b2326; hypothetical protein 2328578 yfcM 7955388 yfcM Escherichia coli BW2952 hypothetical protein YP_002927297.1 2328030 R 595496 CDS YP_002927298.1 238901502 7952839 complement(2328578..2329387) 1 NC_012759.1 MG1655 equivalent: b2327; hypothetical protein 2329387 yfcA 7952839 yfcA Escherichia coli BW2952 hypothetical protein YP_002927298.1 2328578 R 595496 CDS YP_002927299.1 238901503 7952678 complement(2329387..2330211) 1 NC_012759.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2330211 mepA 7952678 mepA Escherichia coli BW2952 penicillin-insensitive murein endopeptidase YP_002927299.1 2329387 R 595496 CDS YP_002927300.1 238901504 7954320 complement(2330215..2331300) 1 NC_012759.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2331300 aroC 7954320 aroC Escherichia coli BW2952 chorismate synthase YP_002927300.1 2330215 R 595496 CDS YP_002927301.1 238901505 7952636 complement(2331335..2332267) 1 NC_012759.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2332267 prmB 7952636 prmB Escherichia coli BW2952 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002927301.1 2331335 R 595496 CDS YP_002927302.1 238901506 7954332 2332433..2332984 1 NC_012759.1 MG1655 equivalent: b2331; hypothetical protein 2332984 yfcN 7954332 yfcN Escherichia coli BW2952 hypothetical protein YP_002927302.1 2332433 D 595496 CDS YP_002927303.1 238901507 7952998 complement(2333055..2333876) 1 NC_012759.1 MG1655 equivalent: b2332; hypothetical protein 2333876 yfcO 7952998 yfcO Escherichia coli BW2952 hypothetical protein YP_002927303.1 2333055 R 595496 CDS YP_002927304.1 238901508 7955389 complement(2333878..2334417) 1 NC_012759.1 MG1655 equivalent: b2333; putative fimbrial-like adhesin protein 2334417 yfcP 7955389 yfcP Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002927304.1 2333878 R 595496 CDS YP_002927305.1 238901509 7954888 complement(2334414..2334902) 1 NC_012759.1 MG1655 equivalent: b2334; putative fimbrial-like adhesin protein 2334902 yfcQ 7954888 yfcQ Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002927305.1 2334414 R 595496 CDS YP_002927306.1 238901510 7954889 complement(2334899..2335411) 1 NC_012759.1 MG1655 equivalent: b2335; putative fimbrial-like adhesin protein 2335411 yfcR 7954889 yfcR Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002927306.1 2334899 R 595496 CDS YP_002927307.1 238901511 7954890 complement(2335411..2336163) 1 NC_012759.1 MG1655 equivalent: b2336; putative periplasmic pilus chaperone 2336163 yfcS 7954890 yfcS Escherichia coli BW2952 putative periplasmic pilus chaperone YP_002927307.1 2335411 R 595496 CDS YP_002927308.1 238901512 7955306 complement(2338910..2339473) 1 NC_012759.1 MG1655 equivalent: b2339; putative fimbrial-like adhesin protein 2339473 yfcV 7955306 yfcV Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002927308.1 2338910 R 595496 CDS YP_002927309.1 238901513 7954891 complement(2340154..2340639) 1 NC_012759.1 MG1655 equivalent: b2340; phosphohistidine phosphatase 2340639 sixA 7954891 sixA Escherichia coli BW2952 phosphohistidine phosphatase YP_002927309.1 2340154 R 595496 CDS YP_002927310.1 238901514 7954539 complement(2340842..2342986) 1 NC_012759.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2342986 fadJ 7954539 fadJ Escherichia coli BW2952 multifunctional fatty acid oxidation complex subunit alpha YP_002927310.1 2340842 R 595496 CDS YP_002927311.1 238901515 7953679 complement(2342986..2344296) 1 NC_012759.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2344296 fadI 7953679 fadI Escherichia coli BW2952 3-ketoacyl-CoA thiolase YP_002927311.1 2342986 R 595496 CDS YP_002927312.1 238901516 7952550 complement(2344477..2344761) 1 NC_012759.1 MG1655 equivalent: b2343; hypothetical protein 2344761 yfcZ 7952550 yfcZ Escherichia coli BW2952 hypothetical protein YP_002927312.1 2344477 R 595496 CDS YP_002927313.1 238901517 7952840 2345133..2346473 1 NC_012759.1 MG1655 equivalent: b2344; long-chain fatty acid outer membrane transporter 2346473 fadL 7952840 fadL Escherichia coli BW2952 long-chain fatty acid outer membrane transporter YP_002927313.1 2345133 D 595496 CDS YP_002927314.1 238901518 7954163 2346839..2347897 1 NC_012759.1 MG1655 equivalent: b2345; hypothetical protein 2347897 yfdF 7954163 yfdF Escherichia coli BW2952 hypothetical protein YP_002927314.1 2346839 D 595496 CDS YP_002927315.1 238901519 7955496 complement(2348079..2348834) 1 NC_012759.1 MG1655 equivalent: b2346; putative lipoprotein 2348834 vacJ 7955496 vacJ Escherichia coli BW2952 putative lipoprotein YP_002927315.1 2348079 R 595496 CDS YP_002927316.1 238901520 7955111 2349128..2350060 1 NC_012759.1 MG1655 equivalent: b2347; putative inner membrane protein 2350060 yfdC 7955111 yfdC Escherichia coli BW2952 putative inner membrane protein YP_002927316.1 2349128 D 595496 CDS YP_002927317.1 238901521 7952136 2350372..2351529 1 NC_012759.1 MG1655 equivalent: b2349; CPS-53 (KpLE1) prophage; putative prophage CPS-53 integrase 2351529 intS 7952136 intS Escherichia coli BW2952 CPS-53 (KpLE1) prophage; putative prophage CPS-53 integrase YP_002927317.1 2350372 D 595496 CDS YP_002927318.1 238901522 7953147 2351682..2352044 1 NC_012759.1 MG1655 equivalent: b2350; CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) 2352044 yfdG 7953147 yfdG Escherichia coli BW2952 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) YP_002927318.1 2351682 D 595496 CDS YP_002927319.1 238901523 7953143 2352041..2352961 1 NC_012759.1 MG1655 equivalent: b2351; CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase 2352961 yfdH 7953143 yfdH Escherichia coli BW2952 CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase YP_002927319.1 2352041 D 595496 CDS YP_002927320.1 238901524 7953142 2352958..2354289 1 NC_012759.1 MG1655 equivalent: b2352; CPS-53 (KpLE1) prophage; putative inner membrane protein 2354289 yfdI 7953142 yfdI Escherichia coli BW2952 CPS-53 (KpLE1) prophage; putative inner membrane protein YP_002927320.1 2352958 D 595496 CDS YP_002927321.1 238901525 7953146 complement(2354904..2355344) 1 NC_012759.1 MG1655 equivalent: b2354; CPS-53 (KpLE1) prophage protein 2355344 yfdK 7953146 yfdK Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927321.1 2354904 R 595496 CDS YP_002927322.1 238901526 7953144 complement(2356214..2356708) 1 NC_012759.1 MG1655 equivalent: b2357; CPS-53 (KpLE1) prophage protein 2356708 yfdN 7953144 yfdN Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927322.1 2356214 R 595496 CDS YP_002927323.1 238901527 7953148 2357431..2357793 1 NC_012759.1 MG1655 equivalent: b2359; CPS-53 (KpLE1) prophage protein 2357793 yfdP 7953148 yfdP Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927323.1 2357431 D 595496 CDS YP_002927324.1 238901528 7953149 2357859..2358683 1 NC_012759.1 MG1655 equivalent: b2360; CPS-53 (KpLE1) prophage protein 2358683 yfdQ 7953149 yfdQ Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927324.1 2357859 D 595496 CDS YP_002927325.1 238901529 7953150 2358811..2359347 1 NC_012759.1 MG1655 equivalent: b2361; CPS-53 (KpLE1) prophage protein 2359347 yfdR 7953150 yfdR Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927325.1 2358811 D 595496 CDS YP_002927326.1 238901530 7953145 2359338..2359700 1 NC_012759.1 MG1655 equivalent: b2362; CPS-53 (KpLE1) prophage protein 2359700 yfdS 7953145 yfdS Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927326.1 2359338 D 595496 CDS YP_002927327.1 238901531 7953151 2359700..2360005 1 NC_012759.1 MG1655 equivalent: b2363; CPS-53 (KpLE1) prophage protein 2360005 yfdT 7953151 yfdT Escherichia coli BW2952 CPS-53 (KpLE1) prophage protein YP_002927327.1 2359700 D 595496 CDS YP_002927328.1 238901532 7953152 2360137..2360337 1 NC_012759.1 MG1655 equivalent: b4501; response regulator inhibitor for tor operon 2360337 torI 7953152 torI Escherichia coli BW2952 response regulator inhibitor for tor operon YP_002927328.1 2360137 D 595496 CDS YP_002927329.1 238901533 7952137 complement(2360521..2361456) 1 NC_012759.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 2361456 dsdC 7952137 dsdC Escherichia coli BW2952 DNA-binding transcriptional regulator DsdC YP_002927329.1 2360521 R 595496 CDS YP_002927330.1 238901534 7953407 2361674..2363011 1 NC_012759.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2363011 dsdX 7953407 dsdX Escherichia coli BW2952 permease DsdX YP_002927330.1 2361674 D 595496 CDS YP_002927331.1 238901535 7955695 2363029..2364357 1 NC_012759.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2364357 dsdA 7955695 dsdA Escherichia coli BW2952 D-serine dehydratase YP_002927331.1 2363029 D 595496 CDS YP_002927332.1 238901536 7953497 complement(2364465..2366003) 1 NC_012759.1 MG1655 equivalent: b2367; putative multidrug efflux system 2366003 emrY 7953497 emrY Escherichia coli BW2952 putative multidrug efflux system YP_002927332.1 2364465 R 595496 CDS YP_002927333.1 238901537 7955173 complement(2366003..2367166) 1 NC_012759.1 MG1655 equivalent: b2368; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 2367166 emrK 7955173 emrK Escherichia coli BW2952 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component YP_002927333.1 2366003 R 595496 CDS YP_002927334.1 238901538 7953515 2367582..2368196 1 NC_012759.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2368196 evgA 7953515 evgA Escherichia coli BW2952 DNA-binding transcriptional activator EvgA YP_002927334.1 2367582 D 595496 CDS YP_002927335.1 238901539 7953353 2368201..2371794 1 NC_012759.1 MG1655 equivalent: b2370; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2371794 evgS 7953353 evgS Escherichia coli BW2952 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_002927335.1 2368201 D 595496 CDS YP_002927336.1 238901540 7953929 complement(2371850..2372995) 1 NC_012759.1 MG1655 equivalent: b2371; hypothetical protein 2372995 yfdE 7953929 yfdE Escherichia coli BW2952 hypothetical protein YP_002927336.1 2371850 R 595496 CDS YP_002927337.1 238901541 7954697 complement(2373069..2374013) 1 NC_012759.1 member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV 2374013 yfdV 7954697 yfdV Escherichia coli BW2952 putative transporter YfdV YP_002927337.1 2373069 R 595496 CDS YP_002927338.1 238901542 7955662 complement(2374083..2375777) 1 NC_012759.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase 2375777 oxc 7955662 oxc Escherichia coli BW2952 putative oxalyl-CoA decarboxylase YP_002927338.1 2374083 R 595496 CDS YP_002927339.1 238901543 7955220 complement(2375831..2377081) 1 NC_012759.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2377081 frc 7955220 frc Escherichia coli BW2952 formyl-coenzyme A transferase YP_002927339.1 2375831 R 595496 CDS YP_002927340.1 238901544 7953629 complement(2377594..2378229) 1 NC_012759.1 MG1655 equivalent: b2375; hypothetical protein 2378229 yfdX 7953629 yfdX Escherichia coli BW2952 hypothetical protein YP_002927340.1 2377594 R 595496 CDS YP_002927341.1 238901545 7955390 2378525..2378800 1 NC_012759.1 MG1655 equivalent: b2376; putative lipoprotein involved in colanic acid biosynthesis 2378800 ypdI 7955390 ypdI Escherichia coli BW2952 putative lipoprotein involved in colanic acid biosynthesis YP_002927341.1 2378525 D 595496 CDS YP_002927342.1 238901546 7955121 complement(2378877..2379119) 1 NC_012759.1 MG1655 equivalent: b2377; putative inner membrane protein 2379119 yfdY 7955121 yfdY Escherichia coli BW2952 putative inner membrane protein YP_002927342.1 2378877 R 595496 CDS YP_002927343.1 238901547 7955002 2379472..2380392 1 NC_012759.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2380392 lpxP 7955002 lpxP Escherichia coli BW2952 lipid A biosynthesis palmitoleoyl acyltransferase YP_002927343.1 2379472 D 595496 CDS YP_002927344.1 238901548 7954461 complement(2380884..2382122) 1 NC_012759.1 MG1655 equivalent: b2379; aminotransferase 2382122 yfdZ 7954461 yfdZ Escherichia coli BW2952 aminotransferase YP_002927344.1 2380884 R 595496 CDS YP_002927345.1 238901549 7955759 2382498..2384195 1 NC_012759.1 MG1655 equivalent: b2380; putative sensory kinase in two-component system with YpdB 2384195 ypdA 7955759 ypdA Escherichia coli BW2952 putative sensory kinase in two-component system with YpdB YP_002927345.1 2382498 D 595496 CDS YP_002927346.1 238901550 7955589 2384210..2384944 1 NC_012759.1 MG1655 equivalent: b2381; putative response regulator in two-component system withYpdA 2384944 ypdB 7955589 ypdB Escherichia coli BW2952 putative response regulator in two-component system withYpdA YP_002927346.1 2384210 D 595496 CDS YP_002927347.1 238901551 7955568 2384957..2385814 1 NC_012759.1 MG1655 equivalent: b2382; putative DNA-binding protein 2385814 ypdC 7955568 ypdC Escherichia coli BW2952 putative DNA-binding protein YP_002927347.1 2384957 D 595496 CDS YP_002927348.1 238901552 7954738 complement(2385817..2388312) 1 NC_012759.1 MG1655 equivalent: b2383; fused putative PTS enzymes: Hpr component/enzyme I component/enzyme IIA component 2388312 fryA 7954738 fryA Escherichia coli BW2952 fused putative PTS enzymes: Hpr component/enzyme I component/enzyme IIA component YP_002927348.1 2385817 R 595496 CDS YP_002927349.1 238901553 7953723 complement(2388337..2389374) 1 NC_012759.1 metalloprotein; exoaminopeptidase 2389374 ypdE 7953723 ypdE Escherichia coli BW2952 exoaminopeptidase YP_002927349.1 2388337 R 595496 CDS YP_002927350.1 238901554 7955275 complement(2389374..2390459) 1 NC_012759.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2390459 ypdF 7955275 ypdF Escherichia coli BW2952 aminopeptidase YP_002927350.1 2389374 R 595496 CDS YP_002927351.1 238901555 7955276 complement(2390474..2391721) 1 NC_012759.1 MG1655 equivalent: b2386; putative enzyme IIC component of PTS 2391721 fryC 7955276 fryC Escherichia coli BW2952 putative enzyme IIC component of PTS YP_002927351.1 2390474 R 595496 CDS YP_002927352.1 238901556 7954856 complement(2391743..2392069) 1 NC_012759.1 MG1655 equivalent: b2387; putative enzyme IIB component of PTS 2392069 fryB 7954856 fryB Escherichia coli BW2952 putative enzyme IIB component of PTS YP_002927352.1 2391743 R 595496 CDS YP_002927353.1 238901557 7954852 complement(2392288..2393253) 1 NC_012759.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2393253 glk 7954852 glk Escherichia coli BW2952 glucokinase YP_002927353.1 2392288 R 595496 CDS YP_002927354.1 238901558 7953796 2393457..2394713 1 NC_012759.1 MG1655 equivalent: b2389; hypothetical protein 2394713 yfeO 7953796 yfeO Escherichia coli BW2952 hypothetical protein YP_002927354.1 2393457 D 595496 CDS YP_002927355.1 238901559 7955086 2394828..2395154 1 NC_012759.1 MG1655 equivalent: b2390; hypothetical protein 2395154 ypeC 7955086 ypeC Escherichia coli BW2952 hypothetical protein YP_002927355.1 2394828 D 595496 CDS YP_002927356.1 238901560 7952999 complement(2395295..2396533) 1 NC_012759.1 MG1655 equivalent: b2392; manganese transport protein MntH 2396533 mntH 7952999 mntH Escherichia coli BW2952 manganese transport protein MntH YP_002927356.1 2395295 R 595496 CDS YP_002927357.1 238901561 7954210 2396869..2398071 1 NC_012759.1 MG1655 equivalent: b2393; nucleoside (except guanosine) transporter 2398071 nupC 7954210 nupC Escherichia coli BW2952 nucleoside (except guanosine) transporter YP_002927357.1 2396869 D 595496 CDS YP_002927358.1 238901562 7954409 2398158..2399270 1 NC_012759.1 MG1655 equivalent: b2394; IS186/IS421 transposase 2399270 insL 7954409 insL Escherichia coli BW2952 IS186/IS421 transposase YP_002927358.1 2398158 D 595496 CDS YP_002927359.1 238901563 7954027 complement(2399470..2401659) 1 NC_012759.1 MG1655 equivalent: b2395; putative diguanylate cyclase 2401659 yfeA 7954027 yfeA Escherichia coli BW2952 putative diguanylate cyclase YP_002927359.1 2399470 R 595496 CDS YP_002927360.1 238901564 7952059 2402294..2402638 1 NC_012759.1 MG1655 equivalent: b2398; putative DNA-binding transcriptional regulator 2402638 yfeC 7952059 yfeC Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927360.1 2402294 D 595496 CDS YP_002927361.1 238901565 7954804 2402661..2403032 1 NC_012759.1 MG1655 equivalent: b2399; putative DNA-binding transcriptional regulator 2403032 yfeD 7954804 yfeD Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927361.1 2402661 D 595496 CDS YP_002927362.1 238901566 7954805 complement(2403084..2404499) 1 NC_012759.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2404499 gltX 7954805 gltX Escherichia coli BW2952 glutamyl-tRNA synthetase YP_002927362.1 2403084 R 595496 CDS YP_002927363.1 238901567 7952141 complement(2405420..2406304) 1 NC_012759.1 MG1655 equivalent: b2405; DNA-binding transcriptional activator XapR 2406304 xapR 7952141 xapR Escherichia coli BW2952 DNA-binding transcriptional activator XapR YP_002927363.1 2405420 R 595496 CDS YP_002927364.1 238901568 7953368 complement(2406556..2407812) 1 NC_012759.1 MG1655 equivalent: b2406; xanthosine transporter 2407812 xapB 7953368 xapB Escherichia coli BW2952 xanthosine transporter YP_002927364.1 2406556 R 595496 CDS YP_002927365.1 238901569 7956279 complement(2407872..2408705) 1 NC_012759.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2408705 xapA 7956279 xapA Escherichia coli BW2952 purine nucleoside phosphorylase YP_002927365.1 2407872 R 595496 CDS YP_002927366.1 238901570 7955823 2408954..2409718 1 NC_012759.1 MG1655 equivalent: b2408; hypothetical protein 2409718 yfeN 7955823 yfeN Escherichia coli BW2952 hypothetical protein YP_002927366.1 2408954 D 595496 CDS YP_002927367.1 238901571 7952750 complement(2409757..2410683) 1 NC_012759.1 MG1655 equivalent: b2409; putative DNA-binding transcriptional regulator 2410683 yfeR 7952750 yfeR Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927367.1 2409757 R 595496 CDS YP_002927368.1 238901572 7954769 2410773..2411771 1 NC_012759.1 MG1655 equivalent: b2410; putative inner membrane protein 2411771 yfeH 7954769 yfeH Escherichia coli BW2952 putative inner membrane protein YP_002927368.1 2410773 D 595496 CDS YP_002927369.1 238901573 7955054 complement(2411768..2411986) 1 NC_012759.1 MG1655 equivalent: b4546; hypothetical protein 2411986 ypeB 7955054 ypeB Escherichia coli BW2952 hypothetical protein YP_002927369.1 2411768 R 595496 CDS YP_002927370.1 238901574 7955434 complement(2411988..2414003) 1 NC_012759.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2414003 ligA 7955434 ligA Escherichia coli BW2952 NAD-dependent DNA ligase LigA YP_002927370.1 2411988 R 595496 CDS YP_002927371.1 238901575 7953311 complement(2414074..2415060) 1 NC_012759.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2415060 zipA 7953311 zipA Escherichia coli BW2952 cell division protein ZipA YP_002927371.1 2414074 R 595496 CDS YP_002927372.1 238901576 7952617 2415290..2416051 1 NC_012759.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 2416051 cysZ 7952617 cysZ Escherichia coli BW2952 putative sulfate transport protein CysZ YP_002927372.1 2415290 D 595496 CDS YP_002927373.1 238901577 7955055 2416236..2417207 1 NC_012759.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2417207 cysK 7955055 cysK Escherichia coli BW2952 cysteine synthase A YP_002927373.1 2416236 D 595496 CDS YP_002927374.1 238901578 7953184 2417591..2417848 1 NC_012759.1 MG1655 equivalent: b2415; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2417848 ptsH 7953184 ptsH Escherichia coli BW2952 PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_002927374.1 2417591 D 595496 CDS YP_002927375.1 238901579 7954541 2417893..2419620 1 NC_012759.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2419620 ptsI 7954541 ptsI Escherichia coli BW2952 phosphoenolpyruvate-protein phosphotransferase YP_002927375.1 2417893 D 595496 CDS YP_002927376.1 238901580 7954471 2419661..2420170 1 NC_012759.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2420170 crr 7954471 crr Escherichia coli BW2952 PTS system glucose-specific transporter YP_002927376.1 2419661 D 595496 CDS YP_002927377.1 238901581 7953812 complement(2420213..2421064) 1 NC_012759.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2421064 pdxK 7953812 pdxK Escherichia coli BW2952 pyridoxal kinase YP_002927377.1 2420213 R 595496 CDS YP_002927378.1 238901582 7955839 2421169..2421543 1 NC_012759.1 MG1655 equivalent: b2419; hypothetical protein 2421543 yfeK 7955839 yfeK Escherichia coli BW2952 hypothetical protein YP_002927378.1 2421169 D 595496 CDS YP_002927379.1 238901583 7955497 2421576..2422310 1 NC_012759.1 MG1655 equivalent: b2420; hypothetical protein 2422310 yfeS 7955497 yfeS Escherichia coli BW2952 hypothetical protein YP_002927379.1 2421576 D 595496 CDS YP_002927380.1 238901584 7953000 complement(2422499..2423410) 1 NC_012759.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2423410 cysM 7953000 cysM Escherichia coli BW2952 cysteine synthase B YP_002927380.1 2422499 R 595496 CDS YP_002927381.1 238901585 7953185 complement(2423544..2424641) 1 NC_012759.1 MG1655 equivalent: b2422; sulfate/thiosulfate transporter subunit 2424641 cysA 7953185 cysA Escherichia coli BW2952 sulfate/thiosulfate transporter subunit YP_002927381.1 2423544 R 595496 CDS YP_002927382.1 238901586 7956091 complement(2424631..2425506) 1 NC_012759.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2425506 cysW 7956091 cysW Escherichia coli BW2952 sulfate/thiosulfate transporter permease subunit YP_002927382.1 2424631 R 595496 CDS YP_002927383.1 238901587 7956092 complement(2425506..2426339) 1 NC_012759.1 MG1655 equivalent: b2424; sulfate/thiosulfate transporter subunit 2426339 cysU 7956092 cysU Escherichia coli BW2952 sulfate/thiosulfate transporter subunit YP_002927383.1 2425506 R 595496 CDS YP_002927384.1 238901588 7956093 complement(2426339..2427355) 1 NC_012759.1 MG1655 equivalent: b2425; thiosulfate transporter subunit 2427355 cysP 7956093 cysP Escherichia coli BW2952 thiosulfate transporter subunit YP_002927384.1 2426339 R 595496 CDS YP_002927385.1 238901589 7956137 complement(2427659..2428450) 1 NC_012759.1 MG1655 equivalent: b2426; short chain dehydrogenase 2428450 ucpA 7956137 ucpA Escherichia coli BW2952 short chain dehydrogenase YP_002927385.1 2427659 R 595496 CDS YP_002927386.1 238901590 7955267 complement(2428579..2429436) 1 NC_012759.1 MG1655 equivalent: b2427; putative DNA-binding transcriptional regulator 2429436 yfeT 7955267 yfeT Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927386.1 2428579 R 595496 CDS YP_002927387.1 238901591 7954770 2429600..2430496 1 NC_012759.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2430496 murQ 7954770 murQ Escherichia coli BW2952 N-acetylmuramic acid 6-phosphate etherase YP_002927387.1 2429600 D 595496 CDS YP_002927388.1 238901592 7955548 2430500..2431924 1 NC_012759.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2431924 murP 7955548 murP Escherichia coli BW2952 PTS system N-acetylmuramic acid transporter subunit IIBC YP_002927388.1 2430500 D 595496 CDS YP_002927389.1 238901593 7953726 2431929..2433233 1 NC_012759.1 MG1655 equivalent: b2430; hypothetical protein 2433233 yfeW 7953726 yfeW Escherichia coli BW2952 hypothetical protein YP_002927389.1 2431929 D 595496 CDS YP_002927390.1 238901594 7955299 complement(2433473..2434372) 1 NC_012759.1 MG1655 equivalent: b2431; hypothetical protein 2434372 yfeX 7955299 yfeX Escherichia coli BW2952 hypothetical protein YP_002927390.1 2433473 R 595496 CDS YP_002927391.1 238901595 7952841 complement(2434468..2435043) 1 NC_012759.1 MG1655 equivalent: b2432; hypothetical protein 2435043 yfeY 7952841 yfeY Escherichia coli BW2952 hypothetical protein YP_002927391.1 2434468 R 595496 CDS YP_002927392.1 238901596 7955391 complement(2435104..2435553) 1 NC_012759.1 MG1655 equivalent: b2433; putative inner membrane protein 2435553 yfeZ 7955391 yfeZ Escherichia coli BW2952 putative inner membrane protein YP_002927392.1 2435104 R 595496 CDS YP_002927393.1 238901597 7955003 complement(2435540..2435965) 1 NC_012759.1 MG1655 equivalent: b2434; putative acetyltransferase 2435965 ypeA 7955003 ypeA Escherichia coli BW2952 putative acetyltransferase YP_002927393.1 2435540 R 595496 CDS YP_002927394.1 238901598 7954617 2436179..2437048 1 NC_012759.1 MG1655 equivalent: b2435; N-acetylmuramoyl-l-alanine amidase I 2437048 amiA 7954617 amiA Escherichia coli BW2952 N-acetylmuramoyl-l-alanine amidase I YP_002927394.1 2436179 D 595496 CDS YP_002927395.1 238901599 7954344 2437052..2437951 1 NC_012759.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2437951 hemF 7954344 hemF Escherichia coli BW2952 coproporphyrinogen III oxidase YP_002927395.1 2437052 D 595496 CDS YP_002927396.1 238901600 7953101 complement(2437957..2439009) 1 NC_012759.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2439009 eutR 7953101 eutR Escherichia coli BW2952 transcriptional regulator EutR YP_002927396.1 2437957 R 595496 CDS YP_002927397.1 238901601 7954771 complement(2439055..2439555) 1 NC_012759.1 MG1655 equivalent: b2438; putative carboxysome structural protein with putative role in ethanolamine utilization 2439555 eutK 7954771 eutK Escherichia coli BW2952 putative carboxysome structural protein with putative role in ethanolamine utilization YP_002927397.1 2439055 R 595496 CDS YP_002927398.1 238901602 7954678 complement(2439568..2440227) 1 NC_012759.1 MG1655 equivalent: b2439; putative carboxysome structural protein with putative role in ethanolamine utilization 2440227 eutL 7954678 eutL Escherichia coli BW2952 putative carboxysome structural protein with putative role in ethanolamine utilization YP_002927398.1 2439568 R 595496 CDS YP_002927399.1 238901603 7954679 complement(2440237..2441124) 1 NC_012759.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2441124 eutC 7954679 eutC Escherichia coli BW2952 ethanolamine ammonia-lyase small subunit YP_002927399.1 2440237 R 595496 CDS YP_002927400.1 238901604 7953535 complement(2441145..2442506) 1 NC_012759.1 MG1655 equivalent: b2441; ethanolamine ammonia-lyase, large subunit, heavy chain 2442506 eutB 7953535 eutB Escherichia coli BW2952 ethanolamine ammonia-lyase, large subunit, heavy chain YP_002927400.1 2441145 R 595496 CDS YP_002927401.1 238901605 7953534 2442685..2443893 1 NC_012759.1 MG1655 equivalent: b2442; CPZ-55 prophage; putative integrase 2443893 intZ 7953534 intZ Escherichia coli BW2952 CPZ-55 prophage; putative integrase YP_002927401.1 2442685 D 595496 CDS YP_002927402.1 238901606 7953153 2444084..2444725 1 NC_012759.1 MG1655 equivalent: b2443; CPZ-55 prophage protein 2444725 yffL 7953153 yffL Escherichia coli BW2952 CPZ-55 prophage protein YP_002927402.1 2444084 D 595496 CDS YP_002927403.1 238901607 7953154 2445195..2445440 1 NC_012759.1 MG1655 equivalent: b2444; CPZ-55 prophage protein 2445440 yffM 7953154 yffM Escherichia coli BW2952 CPZ-55 prophage protein YP_002927403.1 2445195 D 595496 CDS YP_002927404.1 238901608 7953155 2445452..2445820 1 NC_012759.1 MG1655 equivalent: b2445; CPZ-55 prophage protein 2445820 yffN 7953155 yffN Escherichia coli BW2952 CPZ-55 prophage protein YP_002927404.1 2445452 D 595496 CDS YP_002927405.1 238901609 7953156 2445938..2446354 1 NC_012759.1 MG1655 equivalent: b2446; CPZ-55 prophage protein 2446354 yffO 7953156 yffO Escherichia coli BW2952 CPZ-55 prophage protein YP_002927405.1 2445938 D 595496 CDS YP_002927406.1 238901610 7953157 2446351..2446944 1 NC_012759.1 MG1655 equivalent: b2447; CPZ-55 prophage protein 2446944 yffP 7953157 yffP Escherichia coli BW2952 CPZ-55 prophage protein YP_002927406.1 2446351 D 595496 CDS YP_002927407.1 238901611 7953158 2447419..2447796 1 NC_012759.1 MG1655 equivalent: b2448; CPZ-55 prophage protein 2447796 yffQ 7953158 yffQ Escherichia coli BW2952 CPZ-55 prophage protein YP_002927407.1 2447419 D 595496 CDS YP_002927408.1 238901612 7953159 2447807..2448199 1 NC_012759.1 MG1655 equivalent: b2449; CPZ-55 prophage protein 2448199 yffR 7953159 yffR Escherichia coli BW2952 CPZ-55 prophage protein YP_002927408.1 2447807 D 595496 CDS YP_002927409.1 238901613 7953160 2448350..2449159 1 NC_012759.1 MG1655 equivalent: b2450; CPZ-55 prophage protein 2449159 yffS 7953160 yffS Escherichia coli BW2952 CPZ-55 prophage protein YP_002927409.1 2448350 D 595496 CDS YP_002927410.1 238901614 7953161 complement(2449308..2450711) 1 NC_012759.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2450711 eutA 7953161 eutA Escherichia coli BW2952 reactivating factor for ethanolamine ammonia lyase YP_002927410.1 2449308 R 595496 CDS YP_002927411.1 238901615 7955914 complement(2450708..2451934) 1 NC_012759.1 MG1655 equivalent: b2452; putative inner membrane protein 2451934 eutH 7955914 eutH Escherichia coli BW2952 putative inner membrane protein YP_002927411.1 2450708 R 595496 CDS YP_002927412.1 238901616 7955004 complement(2452151..2453338) 1 NC_012759.1 MG1655 equivalent: b2453; putative alcohol dehydrogenase in ethanolamine utilization 2453338 eutG 7955004 eutG Escherichia coli BW2952 putative alcohol dehydrogenase in ethanolamine utilization YP_002927412.1 2452151 R 595496 CDS YP_002927413.1 238901617 7954625 complement(2453328..2454164) 1 NC_012759.1 MG1655 equivalent: b2454; putative chaperonin, ethanolamine utilization protein 2454164 eutJ 7954625 eutJ Escherichia coli BW2952 putative chaperonin, ethanolamine utilization protein YP_002927413.1 2453328 R 595496 CDS YP_002927414.1 238901618 7954691 complement(2454175..2455578) 1 NC_012759.1 MG1655 equivalent: b2455; putative aldehyde dehydrogenase, ethanolamine utilization protein 2455578 eutE 7954691 eutE Escherichia coli BW2952 putative aldehyde dehydrogenase, ethanolamine utilization protein YP_002927414.1 2454175 R 595496 CDS YP_002927415.1 238901619 7954628 complement(2455590..2455877) 1 NC_012759.1 MG1655 equivalent: b2456; putative carboxysome structural protein, ethanolamine utilization protein 2455877 eutN 7954628 eutN Escherichia coli BW2952 putative carboxysome structural protein, ethanolamine utilization protein YP_002927415.1 2455590 R 595496 CDS YP_002927416.1 238901620 7954680 complement(2455984..2456277) 1 NC_012759.1 MG1655 equivalent: b2457; putative carboxysome structural protein, ethanolamine utilization protein 2456277 eutM 7954680 eutM Escherichia coli BW2952 putative carboxysome structural protein, ethanolamine utilization protein YP_002927416.1 2455984 R 595496 CDS YP_002927417.1 238901621 7954681 complement(2456316..2457332) 1 NC_012759.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2457332 eutD 7954681 eutD Escherichia coli BW2952 phosphotransacetylase YP_002927417.1 2456316 R 595496 CDS YP_002927418.1 238901622 7955320 complement(2457329..2458132) 1 NC_012759.1 MG1655 equivalent: b2459; putative cobalamin adenosyltransferase in ethanolamine utilization 2458132 eutT 7955320 eutT Escherichia coli BW2952 putative cobalamin adenosyltransferase in ethanolamine utilization YP_002927418.1 2457329 R 595496 CDS YP_002927419.1 238901623 7954698 complement(2458129..2458830) 1 NC_012759.1 MG1655 equivalent: b2460; hypothetical protein 2458830 eutQ 7954698 eutQ Escherichia coli BW2952 hypothetical protein YP_002927419.1 2458129 R 595496 CDS YP_002927420.1 238901624 7952842 complement(2458805..2459284) 1 NC_012759.1 MG1655 equivalent: b2461; hypothetical protein 2459284 eutP 7952842 eutP Escherichia coli BW2952 hypothetical protein YP_002927420.1 2458805 R 595496 CDS YP_002927421.1 238901625 7953085 complement(2459297..2459632) 1 NC_012759.1 MG1655 equivalent: b2462; putative carboxysome structural protein with putative role in ethanol utilization 2459632 eutS 7953085 eutS Escherichia coli BW2952 putative carboxysome structural protein with putative role in ethanol utilization YP_002927421.1 2459297 R 595496 CDS YP_002927422.1 238901626 7954677 complement(2459925..2462204) 1 NC_012759.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2462204 maeB 7954677 maeB Escherichia coli BW2952 malic enzyme YP_002927422.1 2459925 R 595496 CDS YP_002927423.1 238901627 7953695 2462493..2463443 1 NC_012759.1 MG1655 equivalent: b2464; transaldolase A 2463443 talA 7953695 talA Escherichia coli BW2952 transaldolase A YP_002927423.1 2462493 D 595496 CDS YP_002927424.1 238901628 7956164 2463463..2465466 1 NC_012759.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2465466 tktB 7956164 tktB Escherichia coli BW2952 transketolase YP_002927424.1 2463463 D 595496 CDS YP_002927425.1 238901629 7956175 complement(2465561..2466604) 1 NC_012759.1 MG1655 equivalent: b2466; hypothetical protein 2466604 ypfG 7956175 ypfG Escherichia coli BW2952 hypothetical protein YP_002927425.1 2465561 R 595496 CDS YP_002927426.1 238901630 7955392 complement(2466730..2467305) 1 NC_012759.1 MG1655 equivalent: b2467; putative NUDIX hydrolase 2467305 nudK 7955392 nudK Escherichia coli BW2952 putative NUDIX hydrolase YP_002927426.1 2466730 R 595496 CDS YP_002927427.1 238901631 7955189 complement(2467373..2469352) 1 NC_012759.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 2469352 aegA 7955189 aegA Escherichia coli BW2952 putative oxidoreductase Fe-S binding subunit YP_002927427.1 2467373 R 595496 CDS YP_002927428.1 238901632 7953720 2469558..2471258 1 NC_012759.1 MG1655 equivalent: b2469; nitrate/nitrite sensor protein NarQ 2471258 narQ 7953720 narQ Escherichia coli BW2952 nitrate/nitrite sensor protein NarQ YP_002927428.1 2469558 D 595496 CDS YP_002927429.1 238901633 7956021 2471422..2474535 1 NC_012759.1 MG1655 equivalent: b2470; aminoglycoside/multidrug efflux system 2474535 acrD 7956021 acrD Escherichia coli BW2952 aminoglycoside/multidrug efflux system YP_002927429.1 2471422 D 595496 CDS YP_002927431.1 238901635 7953969 2475074..2475430 1 NC_012759.1 MG1655 equivalent: b2471; hypothetical protein 2475430 yffB 7953969 yffB Escherichia coli BW2952 hypothetical protein YP_002927431.1 2475074 D 595496 CDS YP_002927432.1 238901636 7953001 2475434..2476561 1 NC_012759.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2476561 dapE 7953001 dapE Escherichia coli BW2952 succinyl-diaminopimelate desuccinylase YP_002927432.1 2475434 D 595496 CDS YP_002927433.1 238901637 7954407 2476589..2476789 1 NC_012759.1 MG1655 equivalent: b4547; hypothetical protein 2476789 ypfN 7954407 ypfN Escherichia coli BW2952 hypothetical protein YP_002927433.1 2476589 D 595496 CDS YP_002927434.1 238901638 7955535 complement(2476899..2477597) 1 NC_012759.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 2477597 ypfH 7955535 ypfH Escherichia coli BW2952 esterase YpfH YP_002927434.1 2476899 R 595496 CDS YP_002927435.1 238901639 7954957 complement(2477671..2479686) 1 NC_012759.1 MG1655 equivalent: b2474; putative hydrolase 2479686 ypfI 7954957 ypfI Escherichia coli BW2952 putative hydrolase YP_002927435.1 2477671 R 595496 CDS YP_002927436.1 238901640 7954958 complement(2479701..2480564) 1 NC_012759.1 MG1655 equivalent: b2475; hypothetical protein 2480564 ypfJ 7954958 ypfJ Escherichia coli BW2952 hypothetical protein YP_002927436.1 2479701 R 595496 CDS YP_002927437.1 238901641 7952843 complement(2480732..2481445) 1 NC_012759.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2481445 purC 7952843 purC Escherichia coli BW2952 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002927437.1 2480732 R 595496 CDS YP_002927438.1 238901642 7954549 complement(2481658..2482692) 1 NC_012759.1 MG1655 equivalent: b2477; lipoprotein 2482692 bamC 7954549 bamC Escherichia coli BW2952 lipoprotein YP_002927438.1 2481658 R 595496 CDS YP_002927439.1 238901643 7954156 complement(2482709..2483587) 1 NC_012759.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2483587 dapA 7954156 dapA Escherichia coli BW2952 dihydrodipicolinate synthase YP_002927439.1 2482709 R 595496 CDS YP_002927440.1 238901644 7953250 2483733..2484305 1 NC_012759.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2484305 gcvR 7953250 gcvR Escherichia coli BW2952 glycine cleavage system transcriptional repressor YP_002927440.1 2483733 D 595496 CDS YP_002927441.1 238901645 7953480 2484305..2484775 1 NC_012759.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2484775 bcp 7953480 bcp Escherichia coli BW2952 thioredoxin-dependent thiol peroxidase YP_002927441.1 2484305 D 595496 CDS YP_002927442.1 238901646 7956133 2485028..2485645 1 NC_012759.1 MG1655 equivalent: b2481; hydrogenase 4, 4Fe-4S subunit 2485645 hyfA 7956133 hyfA Escherichia coli BW2952 hydrogenase 4, 4Fe-4S subunit YP_002927442.1 2485028 D 595496 CDS YP_002927443.1 238901647 7953948 2485645..2487663 1 NC_012759.1 MG1655 equivalent: b2482; hydrogenase 4 subunit B 2487663 hyfB 7953948 hyfB Escherichia coli BW2952 hydrogenase 4 subunit B YP_002927443.1 2485645 D 595496 CDS YP_002927444.1 238901648 7953951 2487674..2488621 1 NC_012759.1 MG1655 equivalent: b2483; hydrogenase 4, membrane subunit 2488621 hyfC 7953951 hyfC Escherichia coli BW2952 hydrogenase 4, membrane subunit YP_002927444.1 2487674 D 595496 CDS YP_002927445.1 238901649 7953952 2488638..2490077 1 NC_012759.1 MG1655 equivalent: b2484; hydrogenase 4 subunit D 2490077 hyfD 7953952 hyfD Escherichia coli BW2952 hydrogenase 4 subunit D YP_002927445.1 2488638 D 595496 CDS YP_002927446.1 238901650 7953953 2490089..2490739 1 NC_012759.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2490739 hyfE 7953953 hyfE Escherichia coli BW2952 hydrogenase 4 membrane subunit YP_002927446.1 2490089 D 595496 CDS YP_002927447.1 238901651 7953954 2490744..2492324 1 NC_012759.1 MG1655 equivalent: b2486; hydrogenase 4 subunit F 2492324 hyfF 7953954 hyfF Escherichia coli BW2952 hydrogenase 4 subunit F YP_002927447.1 2490744 D 595496 CDS YP_002927448.1 238901652 7953955 2492314..2493981 1 NC_012759.1 MG1655 equivalent: b2487; hydrogenase 4 subunit 2493981 hyfG 7953955 hyfG Escherichia coli BW2952 hydrogenase 4 subunit YP_002927448.1 2492314 D 595496 CDS YP_002927449.1 238901653 7953956 2493991..2494536 1 NC_012759.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2494536 hyfH 7953956 hyfH Escherichia coli BW2952 hydrogenase 4 subunit H YP_002927449.1 2493991 D 595496 CDS YP_002927450.1 238901654 7953949 2494533..2495291 1 NC_012759.1 MG1655 equivalent: b2489; hydrogenase 4, Fe-S subunit 2495291 hyfI 7953949 hyfI Escherichia coli BW2952 hydrogenase 4, Fe-S subunit YP_002927450.1 2494533 D 595496 CDS YP_002927451.1 238901655 7953950 2495284..2495697 1 NC_012759.1 MG1655 equivalent: b2490; putative processing element hydrogenase 4 2495697 hyfJ 7953950 hyfJ Escherichia coli BW2952 putative processing element hydrogenase 4 YP_002927451.1 2495284 D 595496 CDS YP_002927452.1 238901656 7955329 2495727..2497739 1 NC_012759.1 MG1655 equivalent: b2491; DNA-binding transcriptional activator, formate sensing 2497739 hyfR 7955329 hyfR Escherichia coli BW2952 DNA-binding transcriptional activator, formate sensing YP_002927452.1 2495727 D 595496 CDS YP_002927453.1 238901657 7953396 2497761..2498609 1 NC_012759.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 2498609 focB 7953396 focB Escherichia coli BW2952 putative formate transporter YP_002927453.1 2497761 D 595496 CDS YP_002927454.1 238901658 7954911 complement(2498647..2499708) 1 NC_012759.1 MG1655 equivalent: b2493; putative inner membrane protein 2499708 yfgO 7954911 yfgO Escherichia coli BW2952 putative inner membrane protein YP_002927454.1 2498647 R 595496 CDS YP_002927455.1 238901659 7955005 2499921..2501384 1 NC_012759.1 MG1655 equivalent: b2494; putative peptidase 2501384 yfgC 7955005 yfgC Escherichia coli BW2952 putative peptidase YP_002927455.1 2499921 D 595496 CDS YP_002927456.1 238901660 7955283 2501405..2501764 1 NC_012759.1 MG1655 equivalent: b2495; putative oxidoreductase 2501764 yfgD 7955283 yfgD Escherichia coli BW2952 putative oxidoreductase YP_002927456.1 2501405 D 595496 CDS YP_002927457.1 238901661 7955236 complement(2501902..2502648) 1 NC_012759.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2502648 hda 7955236 hda Escherichia coli BW2952 DNA replication initiation factor YP_002927457.1 2501902 R 595496 CDS YP_002927458.1 238901662 7952526 complement(2502698..2503987) 1 NC_012759.1 MG1655 equivalent: b2497; uracil transporter 2503987 uraA 7952526 uraA Escherichia coli BW2952 uracil transporter YP_002927458.1 2502698 R 595496 CDS YP_002927459.1 238901663 7956257 complement(2504073..2504699) 1 NC_012759.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2504699 upp 7956257 upp Escherichia coli BW2952 uracil phosphoribosyltransferase YP_002927459.1 2504073 R 595496 CDS YP_002927460.1 238901664 7956256 2505024..2506061 1 NC_012759.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2506061 purM 7956256 purM Escherichia coli BW2952 phosphoribosylaminoimidazole synthetase YP_002927460.1 2505024 D 595496 CDS YP_002927461.1 238901665 7954548 2506061..2506699 1 NC_012759.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2506699 purN 7954548 purN Escherichia coli BW2952 phosphoribosylglycinamide formyltransferase YP_002927461.1 2506061 D 595496 CDS YP_002927462.1 238901666 7954551 2506871..2508937 1 NC_012759.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2508937 ppk 7954551 ppk Escherichia coli BW2952 polyphosphate kinase YP_002927462.1 2506871 D 595496 CDS YP_002927463.1 238901667 7954569 2508942..2510483 1 NC_012759.1 MG1655 equivalent: b2502; exopolyphosphatase 2510483 ppx 7954569 ppx Escherichia coli BW2952 exopolyphosphatase YP_002927463.1 2508942 D 595496 CDS YP_002927464.1 238901668 7953548 complement(2510522..2512765) 1 NC_012759.1 MG1655 equivalent: b2503; putative inner membrane protein 2512765 yfgF 7953548 yfgF Escherichia coli BW2952 putative inner membrane protein YP_002927464.1 2510522 R 595496 CDS YP_002927465.1 238901669 7955006 2513117..2513308 1 NC_012759.1 MG1655 equivalent: b2504; hypothetical protein 2513308 yfgG 7955006 yfgG Escherichia coli BW2952 hypothetical protein YP_002927465.1 2513117 D 595496 CDS YP_002927466.1 238901670 7955498 2513619..2514137 1 NC_012759.1 MG1655 equivalent: b2505; putative outer membrane lipoprotein 2514137 yfgH 7955498 yfgH Escherichia coli BW2952 putative outer membrane lipoprotein YP_002927466.1 2513619 D 595496 CDS YP_002927467.1 238901671 7955202 2514153..2514692 1 NC_012759.1 MG1655 equivalent: b2506; hypothetical protein 2514692 yfgI 7955202 yfgI Escherichia coli BW2952 hypothetical protein YP_002927467.1 2514153 D 595496 CDS YP_002927468.1 238901672 7953002 complement(2514785..2516362) 1 NC_012759.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2516362 guaA 7953002 guaA Escherichia coli BW2952 GMP synthase YP_002927468.1 2514785 R 595496 CDS YP_002927469.1 238901673 7953873 complement(2516431..2517897) 1 NC_012759.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2517897 guaB 7953873 guaB Escherichia coli BW2952 inosine 5'-monophosphate dehydrogenase YP_002927469.1 2516431 R 595496 CDS YP_002927470.1 238901674 7953993 2518059..2519429 1 NC_012759.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2519429 xseA 7953993 xseA Escherichia coli BW2952 exodeoxyribonuclease VII large subunit YP_002927470.1 2518059 D 595496 CDS YP_002927471.1 238901675 7953545 complement(2519426..2519641) 1 NC_012759.1 MG1655 equivalent: b2510; hypothetical protein 2519641 yfgJ 7953545 yfgJ Escherichia coli BW2952 hypothetical protein YP_002927471.1 2519426 R 595496 CDS YP_002927472.1 238901676 7955393 complement(2519711..2521183) 1 NC_012759.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2521183 engA 7955393 engA Escherichia coli BW2952 GTP-binding protein EngA YP_002927472.1 2519711 R 595496 CDS YP_002927473.1 238901677 7954942 complement(2521301..2522479) 1 NC_012759.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2522479 bamB 7954942 bamB Escherichia coli BW2952 outer membrane protein assembly complex subunit YfgL YP_002927473.1 2521301 R 595496 CDS YP_002927474.1 238901678 7955781 complement(2522490..2523110) 1 NC_012759.1 MG1655 equivalent: b2513; hypothetical protein 2523110 yfgM 7955781 yfgM Escherichia coli BW2952 hypothetical protein YP_002927474.1 2522490 R 595496 CDS YP_002927475.1 238901679 7952844 complement(2523128..2524402) 1 NC_012759.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2524402 hisS 7952844 hisS Escherichia coli BW2952 histidyl-tRNA synthetase YP_002927475.1 2523128 R 595496 CDS YP_002927476.1 238901680 7953914 complement(2524513..2525631) 1 NC_012759.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2525631 ispG 7953914 ispG Escherichia coli BW2952 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002927476.1 2524513 R 595496 CDS YP_002927477.1 238901681 7952230 complement(2525658..2526671) 1 NC_012759.1 MG1655 equivalent: b2516; cytoskeletal protein RodZ 2526671 yfgA 7952230 yfgA Escherichia coli BW2952 cytoskeletal protein RodZ YP_002927477.1 2525658 R 595496 CDS YP_002927478.1 238901682 7952845 complement(2526956..2528110) 1 NC_012759.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2528110 rlmN 7952845 rlmN Escherichia coli BW2952 ribosomal RNA large subunit methyltransferase N YP_002927478.1 2526956 R 595496 CDS YP_002927479.1 238901683 7954842 complement(2528260..2528691) 1 NC_012759.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2528691 ndk 7954842 ndk Escherichia coli BW2952 nucleoside diphosphate kinase YP_002927479.1 2528260 R 595496 CDS YP_002927480.1 238901684 7954318 complement(2528840..2531152) 1 NC_012759.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2531152 pbpC 7954318 pbpC Escherichia coli BW2952 penicillin-binding protein 1C YP_002927480.1 2528840 R 595496 CDS YP_002927481.1 238901685 7953747 complement(2531153..2536114) 1 NC_012759.1 MG1655 equivalent: b2520; hypothetical protein 2536114 yfhM 7953747 yfhM Escherichia coli BW2952 hypothetical protein YP_002927481.1 2531153 R 595496 CDS YP_002927482.1 238901686 7952846 2536321..2537166 1 NC_012759.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2537166 sseA 7952846 sseA Escherichia coli BW2952 3-mercaptopyruvate sulfurtransferase YP_002927482.1 2536321 D 595496 CDS YP_002927483.1 238901687 7952187 complement(2537984..2538760) 1 NC_012759.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2538760 sseB 7952187 sseB Escherichia coli BW2952 enhanced serine sensitivity protein SseB YP_002927483.1 2537984 R 595496 CDS YP_002927484.1 238901688 7955948 complement(2538902..2540185) 1 NC_012759.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 2540185 pepB 7955948 pepB Escherichia coli BW2952 aminopeptidase B YP_002927484.1 2538902 R 595496 CDS YP_002927485.1 238901689 7952471 complement(2540363..2540563) 1 NC_012759.1 MG1655 equivalent: b2524; hypothetical protein 2540563 iscX 7952471 iscX Escherichia coli BW2952 hypothetical protein YP_002927485.1 2540363 R 595496 CDS YP_002927486.1 238901690 7952847 complement(2540575..2540910) 1 NC_012759.1 MG1655 equivalent: b2525; [2Fe-2S] ferredoxin 2540910 fdx 7952847 fdx Escherichia coli BW2952 [2Fe-2S] ferredoxin YP_002927486.1 2540575 R 595496 CDS YP_002927487.1 238901691 7952218 complement(2540912..2542762) 1 NC_012759.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2542762 hscA 7952218 hscA Escherichia coli BW2952 chaperone protein HscA YP_002927487.1 2540912 R 595496 CDS YP_002927488.1 238901692 7953490 complement(2542779..2543294) 1 NC_012759.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2543294 hscB 7953490 hscB Escherichia coli BW2952 co-chaperone HscB YP_002927488.1 2542779 R 595496 CDS YP_002927489.1 238901693 7953488 complement(2543390..2543713) 1 NC_012759.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2543713 iscA 7953488 iscA Escherichia coli BW2952 iron-sulfur cluster assembly protein YP_002927489.1 2543390 R 595496 CDS YP_002927490.1 238901694 7953575 complement(2543730..2544116) 1 NC_012759.1 MG1655 equivalent: b2529; scaffold protein 2544116 iscU 7953575 iscU Escherichia coli BW2952 scaffold protein YP_002927490.1 2543730 R 595496 CDS YP_002927491.1 238901695 7956001 complement(2544144..2545358) 1 NC_012759.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2545358 iscS 7956001 iscS Escherichia coli BW2952 cysteine desulfurase YP_002927491.1 2544144 R 595496 CDS YP_002927492.1 238901696 7953182 complement(2545470..2545958) 1 NC_012759.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2545958 iscR 7953182 iscR Escherichia coli BW2952 DNA-binding transcriptional regulator IscR YP_002927492.1 2545470 R 595496 CDS YP_002927493.1 238901697 7953454 complement(2546410..2547150) 1 NC_012759.1 MG1655 equivalent: b2532; putative methyltransferase 2547150 trmJ 7953454 trmJ Escherichia coli BW2952 putative methyltransferase YP_002927493.1 2546410 R 595496 CDS YP_002927494.1 238901698 7955153 2547269..2548072 1 NC_012759.1 MG1655 equivalent: b2533; inositol monophosphatase 2548072 suhB 7955153 suhB Escherichia coli BW2952 inositol monophosphatase YP_002927494.1 2547269 D 595496 CDS YP_002927495.1 238901699 7954001 2548190..2549071 1 NC_012759.1 MG1655 equivalent: b2534; putative peptidase 2549071 yfhR 7954001 yfhR Escherichia coli BW2952 putative peptidase YP_002927495.1 2548190 D 595496 CDS YP_002927496.1 238901700 7955284 2549262..2550542 1 NC_012759.1 MG1655 equivalent: b2535; stationary phase inducible protein CsiE 2550542 csiE 7955284 csiE Escherichia coli BW2952 stationary phase inducible protein CsiE YP_002927496.1 2549262 D 595496 CDS YP_002927497.1 238901701 7956066 complement(2550534..2551673) 1 NC_012759.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 2551673 hcaT 7956066 hcaT Escherichia coli BW2952 putative 3-phenylpropionic acid transporter YP_002927497.1 2550534 R 595496 CDS YP_002927498.1 238901702 7954589 complement(2551833..2552723) 1 NC_012759.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 2552723 hcaR 7954589 hcaR Escherichia coli BW2952 DNA-binding transcriptional regulator HcaR YP_002927498.1 2551833 R 595496 CDS YP_002927499.1 238901703 7953387 2552859..2554220 1 NC_012759.1 MG1655 equivalent: b2538; 3-phenylpropionate dioxygenase, large (alpha) subunit 2554220 hcaE 7953387 hcaE Escherichia coli BW2952 3-phenylpropionate dioxygenase, large (alpha) subunit YP_002927499.1 2552859 D 595496 CDS YP_002927500.1 238901704 7952321 2554217..2554735 1 NC_012759.1 MG1655 equivalent: b2539; 3-phenylpropionate dioxygenase subunit beta 2554735 hcaF 7952321 hcaF Escherichia coli BW2952 3-phenylpropionate dioxygenase subunit beta YP_002927500.1 2554217 D 595496 CDS YP_002927501.1 238901705 7952323 2554735..2555055 1 NC_012759.1 MG1655 equivalent: b2540; 3-phenylpropionate dioxygenase ferredoxin subunit 2555055 hcaC 7952323 hcaC Escherichia coli BW2952 3-phenylpropionate dioxygenase ferredoxin subunit YP_002927501.1 2554735 D 595496 CDS YP_002927502.1 238901706 7952322 2555052..2555864 1 NC_012759.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2555864 hcaB 7952322 hcaB Escherichia coli BW2952 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_002927502.1 2555052 D 595496 CDS YP_002927503.1 238901707 7952234 2555874..2557076 1 NC_012759.1 MG1655 equivalent: b2542; phenylpropionate dioxygenase ferredoxin reductase subunit 2557076 hcaD 7952234 hcaD Escherichia coli BW2952 phenylpropionate dioxygenase ferredoxin reductase subunit YP_002927503.1 2555874 D 595496 CDS YP_002927504.1 238901708 7954512 2557173..2557595 1 NC_012759.1 MG1655 equivalent: b2543; putative inner membrane protein 2557595 yphA 7954512 yphA Escherichia coli BW2952 putative inner membrane protein YP_002927504.1 2557173 D 595496 CDS YP_002927505.1 238901709 7955056 complement(2557643..2558515) 1 NC_012759.1 MG1655 equivalent: b2544; hypothetical protein 2558515 yphB 7955056 yphB Escherichia coli BW2952 hypothetical protein YP_002927505.1 2557643 R 595496 CDS YP_002927506.1 238901710 7952848 complement(2558527..2559588) 1 NC_012759.1 MG1655 equivalent: b2545; putative oxidoreductase, Zn-dependent and NAD(P)-binding 2559588 yphC 7952848 yphC Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002927506.1 2558527 R 595496 CDS YP_002927507.1 238901711 7955261 complement(2559654..2560652) 1 NC_012759.1 MG1655 equivalent: b2546; putative sugar transporter subunit: membrane component of ABC superfamily 2560652 yphD 7955261 yphD Escherichia coli BW2952 putative sugar transporter subunit: membrane component of ABC superfamily YP_002927507.1 2559654 R 595496 CDS YP_002927508.1 238901712 7955606 complement(2560677..2562188) 1 NC_012759.1 MG1655 equivalent: b2547; fused putative sugar transporter subunits of ABC superfamily: ATP-binding components 2562188 yphE 7955606 yphE Escherichia coli BW2952 fused putative sugar transporter subunits of ABC superfamily: ATP-binding components YP_002927508.1 2560677 R 595496 CDS YP_002927509.1 238901713 7953728 complement(2562211..2563194) 1 NC_012759.1 MG1655 equivalent: b2548; putative sugar transporter subunit: periplasmic-binding component of ABC superfamily 2563194 yphF 7953728 yphF Escherichia coli BW2952 putative sugar transporter subunit: periplasmic-binding component of ABC superfamily YP_002927509.1 2562211 R 595496 CDS YP_002927510.1 238901714 7955609 complement(2563291..2566572) 1 NC_012759.1 MG1655 equivalent: b2549; hypothetical protein 2566572 yphG 7955609 yphG Escherichia coli BW2952 hypothetical protein YP_002927510.1 2563291 R 595496 CDS YP_002927511.1 238901715 7952849 2566690..2567883 1 NC_012759.1 MG1655 equivalent: b2550; putative DNA-binding transcriptional regulator 2567883 yphH 7952849 yphH Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927511.1 2566690 D 595496 CDS YP_002927512.1 238901716 7954806 complement(2568081..2569334) 1 NC_012759.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2569334 glyA 7954806 glyA Escherichia coli BW2952 serine hydroxymethyltransferase YP_002927512.1 2568081 R 595496 CDS YP_002927513.1 238901717 7956032 2569662..2570852 1 NC_012759.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2570852 hmp 7956032 hmp Escherichia coli BW2952 nitric oxide dioxygenase YP_002927513.1 2569662 D 595496 CDS YP_002927514.1 238901718 7953704 complement(2570897..2571235) 1 NC_012759.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2571235 glnB 7953704 glnB Escherichia coli BW2952 nitrogen regulatory protein P-II 1 YP_002927514.1 2570897 R 595496 CDS YP_002927515.1 238901719 7955936 complement(2571296..2572630) 1 NC_012759.1 MG1655 equivalent: b2554; putative DNA-binding response regulator in two-component system 2572630 yfhA 7955936 yfhA Escherichia coli BW2952 putative DNA-binding response regulator in two-component system YP_002927515.1 2571296 R 595496 CDS YP_002927516.1 238901720 7954741 complement(2572620..2573333) 1 NC_012759.1 MG1655 equivalent: b2555; hypothetical protein 2573333 yfhG 7954741 yfhG Escherichia coli BW2952 hypothetical protein YP_002927516.1 2572620 R 595496 CDS YP_002927517.1 238901721 7952850 complement(2573498..2574925) 1 NC_012759.1 MG1655 equivalent: b2556; putative sensory kinase in two-component system 2574925 yfhK 7952850 yfhK Escherichia coli BW2952 putative sensory kinase in two-component system YP_002927517.1 2573498 R 595496 CDS YP_002927518.1 238901722 7952087 complement(2575483..2579370) 1 NC_012759.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2579370 purL 7952087 purL Escherichia coli BW2952 phosphoribosylformylglycinamidine synthase YP_002927518.1 2575483 R 595496 CDS YP_002927519.1 238901723 7954550 2579628..2581184 1 NC_012759.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 2581184 yfhD 7954550 yfhD Escherichia coli BW2952 putative transglycosylase YP_002927519.1 2579628 D 595496 CDS YP_002927520.1 238901724 7955297 complement(2581181..2581684) 1 NC_012759.1 MG1655 equivalent: b2559; tRNA-specific adenosine deaminase 2581684 tadA 7955297 tadA Escherichia coli BW2952 tRNA-specific adenosine deaminase YP_002927520.1 2581181 R 595496 CDS YP_002927521.1 238901725 7956208 complement(2581742..2582377) 1 NC_012759.1 MG1655 equivalent: b2560; hypothetical protein 2582377 yfhB 7956208 yfhB Escherichia coli BW2952 hypothetical protein YP_002927521.1 2581742 R 595496 CDS YP_002927522.1 238901726 7952851 2582586..2583434 1 NC_012759.1 MG1655 equivalent: b2561; putative DNA-binding transcriptional regulator 2583434 yfhH 7952851 yfhH Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927522.1 2582586 D 595496 CDS YP_002927523.1 238901727 7954807 2583490..2583750 1 NC_012759.1 MG1655 equivalent: b2562; putative 4Fe-4S cluster-containing protein 2583750 yfhL 7954807 yfhL Escherichia coli BW2952 putative 4Fe-4S cluster-containing protein YP_002927523.1 2583490 D 595496 CDS YP_002927524.1 238901728 7952188 complement(2584445..2584825) 1 NC_012759.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2584825 acpS 7952188 acpS Escherichia coli BW2952 4'-phosphopantetheinyl transferase YP_002927524.1 2584445 R 595496 CDS YP_002927525.1 238901729 7953917 complement(2584825..2585556) 1 NC_012759.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2585556 pdxJ 7953917 pdxJ Escherichia coli BW2952 pyridoxine 5'-phosphate synthase YP_002927525.1 2584825 R 595496 CDS YP_002927526.1 238901730 7955841 complement(2585568..2586296) 1 NC_012759.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2586296 recO 7955841 recO Escherichia coli BW2952 DNA repair protein RecO YP_002927526.1 2585568 R 595496 CDS YP_002927527.1 238901731 7953773 complement(2586308..2587213) 1 NC_012759.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2587213 era 7953773 era Escherichia coli BW2952 GTP-binding protein Era YP_002927527.1 2586308 R 595496 CDS YP_002927528.1 238901732 7954238 complement(2587210..2587890) 1 NC_012759.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2587890 rnc 7954238 rnc Escherichia coli BW2952 ribonuclease III YP_002927528.1 2587210 R 595496 CDS YP_002927529.1 238901733 7955994 complement(2588162..2589136) 1 NC_012759.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2589136 lepB 7955994 lepB Escherichia coli BW2952 signal peptidase I YP_002927529.1 2588162 R 595496 CDS YP_002927530.1 238901734 7954123 complement(2589152..2590951) 1 NC_012759.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2590951 lepA 7954123 lepA Escherichia coli BW2952 GTP-binding protein LepA YP_002927530.1 2589152 R 595496 CDS YP_002927531.1 238901735 7953880 complement(2591149..2591628) 1 NC_012759.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2591628 rseC 7953880 rseC Escherichia coli BW2952 SoxR reducing system protein RseC YP_002927531.1 2591149 R 595496 CDS YP_002927532.1 238901736 7955995 complement(2591625..2592581) 1 NC_012759.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2592581 rseB 7955995 rseB Escherichia coli BW2952 periplasmic negative regulator of sigmaE YP_002927532.1 2591625 R 595496 CDS YP_002927533.1 238901737 7952482 complement(2592581..2593231) 1 NC_012759.1 MG1655 equivalent: b2572; anti-RNA polymerase sigma factor SigE 2593231 rseA 7952482 rseA Escherichia coli BW2952 anti-RNA polymerase sigma factor SigE YP_002927533.1 2592581 R 595496 CDS YP_002927534.1 238901738 7952483 complement(2593264..2593839) 1 NC_012759.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2593839 rpoE 7952483 rpoE Escherichia coli BW2952 RNA polymerase sigma factor RpoE YP_002927534.1 2593264 R 595496 CDS YP_002927535.1 238901739 7955987 2594247..2595869 1 NC_012759.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2595869 nadB 7955987 nadB Escherichia coli BW2952 L-aspartate oxidase YP_002927535.1 2594247 D 595496 CDS YP_002927536.1 238901740 7955887 complement(2595854..2596591) 1 NC_012759.1 MG1655 equivalent: b2575; putative S-adenosyl-L-methionine-dependent methyltransferase 2596591 yfiC 7955887 yfiC Escherichia coli BW2952 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002927536.1 2595854 R 595496 CDS YP_002927537.1 238901741 7955575 2596723..2598057 1 NC_012759.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2598057 srmB 7955575 srmB Escherichia coli BW2952 ATP-dependent RNA helicase SrmB YP_002927537.1 2596723 D 595496 CDS YP_002927538.1 238901742 7952536 complement(2598266..2599147) 1 NC_012759.1 MG1655 equivalent: b2577; putative DNA-binding transcriptional regulator 2599147 yfiE 7952536 yfiE Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927538.1 2598266 R 595496 CDS YP_002927539.1 238901743 7954772 2599250..2599837 1 NC_012759.1 MG1655 equivalent: b2578; neutral amino-acid efflux protein 2599837 eamB 7954772 eamB Escherichia coli BW2952 neutral amino-acid efflux protein YP_002927539.1 2599250 D 595496 CDS YP_002927540.1 238901744 7954375 complement(2599893..2600276) 1 NC_012759.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2600276 yfiD 7954375 yfiD Escherichia coli BW2952 autonomous glycyl radical cofactor GrcA YP_002927540.1 2599893 R 595496 CDS YP_002927541.1 238901745 7955850 2600581..2601270 1 NC_012759.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2601270 ung 7955850 ung Escherichia coli BW2952 uracil-DNA glycosylase YP_002927541.1 2600581 D 595496 CDS YP_002927542.1 238901746 7956258 complement(2601318..2602355) 1 NC_012759.1 MG1655 equivalent: b2581; putative methyltransferase 2602355 yfiF 7956258 yfiF Escherichia coli BW2952 putative methyltransferase YP_002927542.1 2601318 R 595496 CDS YP_002927543.1 238901747 7955154 2602562..2602981 1 NC_012759.1 MG1655 equivalent: b2582; thioredoxin 2 2602981 trxC 7955154 trxC Escherichia coli BW2952 thioredoxin 2 YP_002927543.1 2602562 D 595496 CDS YP_002927544.1 238901748 7956135 2603050..2603748 1 NC_012759.1 MG1655 equivalent: b2583; hypothetical protein 2603748 yfiP 7956135 yfiP Escherichia coli BW2952 hypothetical protein YP_002927544.1 2603050 D 595496 CDS YP_002927545.1 238901749 7953003 2603780..2606440 1 NC_012759.1 MG1655 equivalent: b2584; fused putative acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit 2606440 yfiQ 7953003 yfiQ Escherichia coli BW2952 fused putative acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit YP_002927545.1 2603780 D 595496 CDS YP_002927546.1 238901750 7953709 2606554..2607909 1 NC_012759.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2607909 pssA 7953709 pssA Escherichia coli BW2952 phosphatidylserine synthase YP_002927546.1 2606554 D 595496 CDS YP_002927547.1 238901751 7954526 2607955..2608278 1 NC_012759.1 MG1655 equivalent: b2586; hypothetical protein 2608278 yfiM 7954526 yfiM Escherichia coli BW2952 hypothetical protein YP_002927547.1 2607955 D 595496 CDS YP_002927548.1 238901752 7955499 complement(2608275..2609573) 1 NC_012759.1 MG1655 equivalent: b2587; alpha-ketoglutarate transporter 2609573 kgtP 7955499 kgtP Escherichia coli BW2952 alpha-ketoglutarate transporter YP_002927548.1 2608275 R 595496 CDS YP_002927549.1 238901753 7952036 complement(2615434..2618007) 1 NC_012759.1 MG1655 equivalent: b2592; protein disaggregation chaperone 2618007 clpB 7952036 clpB Escherichia coli BW2952 protein disaggregation chaperone YP_002927549.1 2615434 R 595496 CDS YP_002927550.1 238901754 7952089 complement(2618137..2618868) 1 NC_012759.1 MG1655 equivalent: b2593; hypothetical protein 2618868 yfiH 7952089 yfiH Escherichia coli BW2952 hypothetical protein YP_002927550.1 2618137 R 595496 CDS YP_002927551.1 238901755 7952852 complement(2618865..2619845) 1 NC_012759.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2619845 rluD 7952852 rluD Escherichia coli BW2952 23S rRNA pseudouridine synthase D YP_002927551.1 2618865 R 595496 CDS YP_002927552.1 238901756 7952247 2619980..2620717 1 NC_012759.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2620717 bamD 7952247 bamD Escherichia coli BW2952 outer membrane protein assembly complex subunit YfiO YP_002927552.1 2619980 D 595496 CDS YP_002927553.1 238901757 7955117 2620988..2621329 1 NC_012759.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2621329 raiA 7955117 raiA Escherichia coli BW2952 translation inhibitor protein RaiA YP_002927553.1 2620988 D 595496 CDS YP_002927555.1 238901759 7954505 2621579..2622739 1 NC_012759.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2622739 pheA 7954505 pheA Escherichia coli BW2952 bifunctional chorismate mutase/prephenate dehydratase YP_002927555.1 2621579 D 595496 CDS YP_002927556.1 238901760 7953663 complement(2622782..2623903) 1 NC_012759.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 2623903 tyrA 7953663 tyrA Escherichia coli BW2952 bifunctional chorismate mutase/prephenate dehydrogenase YP_002927556.1 2622782 R 595496 CDS YP_002927557.1 238901761 7953664 complement(2623914..2624984) 1 NC_012759.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2624984 aroF 7953664 aroF Escherichia coli BW2952 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002927557.1 2623914 R 595496 CDS YP_002927558.1 238901762 7952299 2625194..2625559 1 NC_012759.1 MG1655 equivalent: b2602; hypothetical protein 2625559 yfiL 7952299 yfiL Escherichia coli BW2952 hypothetical protein YP_002927558.1 2625194 D 595496 CDS YP_002927559.1 238901763 7955500 2625709..2626227 1 NC_012759.1 MG1655 equivalent: b2603; hypothetical protein 2626227 yfiR 7955500 yfiR Escherichia coli BW2952 hypothetical protein YP_002927559.1 2625709 D 595496 CDS YP_002927560.1 238901764 7955501 2626217..2627443 1 NC_012759.1 MG1655 equivalent: b2604; hypothetical protein 2627443 yfiN 7955501 yfiN Escherichia coli BW2952 hypothetical protein YP_002927560.1 2626217 D 595496 CDS YP_002927561.1 238901765 7954732 2627459..2627941 1 NC_012759.1 MG1655 equivalent: b2605; putative outer membrane lipoprotein 2627941 yfiB 7954732 yfiB Escherichia coli BW2952 putative outer membrane lipoprotein YP_002927561.1 2627459 D 595496 CDS YP_002927562.1 238901766 7955203 complement(2628017..2628364) 1 NC_012759.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2628364 rplS 7955203 rplS Escherichia coli BW2952 50S ribosomal protein L19 YP_002927562.1 2628017 R 595496 CDS YP_002927563.1 238901767 7952346 complement(2628406..2629173) 1 NC_012759.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 2629173 trmD 7952346 trmD Escherichia coli BW2952 tRNA (guanine-N(1)-)-methyltransferase YP_002927563.1 2628406 R 595496 CDS YP_002927564.1 238901768 7956196 complement(2629204..2629752) 1 NC_012759.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2629752 rimM 7956196 rimM Escherichia coli BW2952 16S rRNA-processing protein RimM YP_002927564.1 2629204 R 595496 CDS YP_002927565.1 238901769 7952224 complement(2629771..2630019) 1 NC_012759.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2630019 rpsP 7952224 rpsP Escherichia coli BW2952 30S ribosomal protein S16 YP_002927565.1 2629771 R 595496 CDS YP_002927566.1 238901770 7952279 complement(2630268..2631629) 1 NC_012759.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 2631629 ffh 7952279 ffh Escherichia coli BW2952 signal recognition particle protein YP_002927566.1 2630268 R 595496 CDS YP_002927567.1 238901771 7956045 2631796..2632587 1 NC_012759.1 MG1655 equivalent: b2611; putative inner membrane protein 2632587 ypjD 7956045 ypjD Escherichia coli BW2952 putative inner membrane protein YP_002927567.1 2631796 D 595496 CDS YP_002927568.1 238901772 7955057 2632632..2633894 1 NC_012759.1 MG1655 equivalent: b4461; hypothetical protein 2633894 yfjD 7955057 yfjD Escherichia coli BW2952 hypothetical protein YP_002927568.1 2632632 D 595496 CDS YP_002927569.1 238901773 7955074 complement(2633949..2634542) 1 NC_012759.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2634542 grpE 7955074 grpE Escherichia coli BW2952 heat shock protein GrpE YP_002927569.1 2633949 R 595496 CDS YP_002927570.1 238901774 7953892 2634665..2635543 1 NC_012759.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2635543 ppnK 7953892 ppnK Escherichia coli BW2952 inorganic polyphosphate/ATP-NAD kinase YP_002927570.1 2634665 D 595496 CDS YP_002927571.1 238901775 7954348 2635629..2637290 1 NC_012759.1 MG1655 equivalent: b2616; recombination and repair protein 2637290 recN 7954348 recN Escherichia coli BW2952 recombination and repair protein YP_002927571.1 2635629 D 595496 CDS YP_002927572.1 238901776 7955915 2637439..2637780 1 NC_012759.1 MG1655 equivalent: b2617; hypothetical protein 2637780 smpA 7955915 smpA Escherichia coli BW2952 hypothetical protein YP_002927572.1 2637439 D 595496 CDS YP_002927573.1 238901777 7956049 complement(2637842..2638132) 1 NC_012759.1 MG1655 equivalent: b2618; hypothetical protein 2638132 yfjF 7956049 yfjF Escherichia coli BW2952 hypothetical protein YP_002927573.1 2637842 R 595496 CDS YP_002927574.1 238901778 7955394 complement(2638122..2638598) 1 NC_012759.1 MG1655 equivalent: b2619; hypothetical protein 2638598 yfjG 7955394 yfjG Escherichia coli BW2952 hypothetical protein YP_002927574.1 2638122 R 595496 CDS YP_002927575.1 238901779 7952853 2638730..2639212 1 NC_012759.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2639212 smpB 7952853 smpB Escherichia coli BW2952 SsrA-binding protein YP_002927575.1 2638730 D 595496 CDS YP_002927576.1 238901780 7952203 2639993..2641234 1 NC_012759.1 CP4-57 prophage; integrase; integrase 2641234 intA 7952203 intA Escherichia coli BW2952 integrase YP_002927576.1 2639993 D 595496 CDS YP_002927577.1 238901781 7953112 complement(2641478..2642434) 1 NC_012759.1 MG1655 equivalent: b2623; CP4-57 prophage protein 2642434 yfjH 7953112 yfjH Escherichia coli BW2952 CP4-57 prophage protein YP_002927577.1 2641478 R 595496 CDS YP_002927578.1 238901782 7953119 2642478..2642690 1 NC_012759.1 MG1655 equivalent: b2624; CP4-57 prophage; DNA-binding transcriptional activator 2642690 alpA 7953119 alpA Escherichia coli BW2952 CP4-57 prophage; DNA-binding transcriptional activator YP_002927578.1 2642478 D 595496 CDS YP_002927579.1 238901783 7953111 2642819..2644228 1 NC_012759.1 MG1655 equivalent: b2625; CP4-57 prophage protein 2644228 yfjI 7953111 yfjI Escherichia coli BW2952 CP4-57 prophage protein YP_002927579.1 2642819 D 595496 CDS YP_002927580.1 238901784 7953122 2644381..2645007 1 NC_012759.1 MG1655 equivalent: b2626; CP4-57 prophage protein 2645007 yfjJ 7953122 yfjJ Escherichia coli BW2952 CP4-57 prophage protein YP_002927580.1 2644381 D 595496 CDS YP_002927581.1 238901785 7953123 complement(2645185..2647374) 1 NC_012759.1 MG1655 equivalent: b2627; CP4-57 prophage protein 2647374 yfjK 7953123 yfjK Escherichia coli BW2952 CP4-57 prophage protein YP_002927581.1 2645185 R 595496 CDS YP_002927582.1 238901786 7953110 complement(2647371..2648987) 1 NC_012759.1 MG1655 equivalent: b2628; CP4-57 prophage protein 2648987 yfjL 7953110 yfjL Escherichia coli BW2952 CP4-57 prophage protein YP_002927582.1 2647371 R 595496 CDS YP_002927583.1 238901787 7953120 complement(2649347..2649610) 1 NC_012759.1 MG1655 equivalent: b2629; CP4-57 prophage protein 2649610 yfjM 7953120 yfjM Escherichia coli BW2952 CP4-57 prophage protein YP_002927583.1 2649347 R 595496 CDS YP_002927584.1 238901788 7953121 2649752..2650825 1 NC_012759.1 MG1655 equivalent: b2630; CP4-57 prophage; RNase LS 2650825 rnlA 7953121 rnlA Escherichia coli BW2952 CP4-57 prophage; RNase LS YP_002927584.1 2649752 D 595496 CDS YP_002927585.1 238901789 7953128 2650818..2651189 1 NC_012759.1 MG1655 equivalent: b2631; CP4-57 prophage protein 2651189 yfjO 7953128 yfjO Escherichia coli BW2952 CP4-57 prophage protein YP_002927585.1 2650818 D 595496 CDS YP_002927586.1 238901790 7953124 2651544..2652407 1 NC_012759.1 MG1655 equivalent: b2632; CP4-57 prophage; putative GTP-binding protein 2652407 yfjP 7953124 yfjP Escherichia coli BW2952 CP4-57 prophage; putative GTP-binding protein YP_002927586.1 2651544 D 595496 CDS YP_002927587.1 238901791 7953116 2652499..2653320 1 NC_012759.1 MG1655 equivalent: b2633; CP4-57 prophage protein 2653320 yfjQ 7953116 yfjQ Escherichia coli BW2952 CP4-57 prophage protein YP_002927587.1 2652499 D 595496 CDS YP_002927588.1 238901792 7953125 2653537..2654238 1 NC_012759.1 MG1655 equivalent: b2634; CP4-57 prophage; putative DNA-binding transcriptional regulator 2654238 yfjR 7953125 yfjR Escherichia coli BW2952 CP4-57 prophage; putative DNA-binding transcriptional regulator YP_002927588.1 2653537 D 595496 CDS YP_002927589.1 238901793 7953115 2654279..2654515 1 NC_012759.1 MG1655 equivalent: b2635; CP4-57 prophage; putative inner membrane protein 2654515 ypjK 7953115 ypjK Escherichia coli BW2952 CP4-57 prophage; putative inner membrane protein YP_002927589.1 2654279 D 595496 CDS YP_002927590.1 238901794 7953117 2654515..2654958 1 NC_012759.1 MG1655 equivalent: b2636; CP4-57 prophage protein 2654958 yfjS 7953117 yfjS Escherichia coli BW2952 CP4-57 prophage protein YP_002927590.1 2654515 D 595496 CDS YP_002927591.1 238901795 7953126 2654982..2655449 1 NC_012759.1 MG1655 equivalent: b2637; CP4-57 prophage protein 2655449 yfjT 7953126 yfjT Escherichia coli BW2952 CP4-57 prophage protein YP_002927591.1 2654982 D 595496 CDS YP_002927592.1 238901796 7953127 2657152..2658855 1 NC_012759.1 MG1655 equivalent: b2642; CP4-57 prophage; putative inner membrane protein 2658855 yfjW 7953127 yfjW Escherichia coli BW2952 CP4-57 prophage; putative inner membrane protein YP_002927592.1 2657152 D 595496 CDS YP_002927593.1 238901797 7953118 2659753..2660211 1 NC_012759.1 MG1655 equivalent: b2643; CP4-57 prophage; putative antirestriction protein 2660211 yfjX 7953118 yfjX Escherichia coli BW2952 CP4-57 prophage; putative antirestriction protein YP_002927593.1 2659753 D 595496 CDS YP_002927594.1 238901798 7953113 2660220..2660702 1 NC_012759.1 MG1655 equivalent: b2644; CP4-57 prophage; putative DNA repair protein 2660702 yfjY 7953113 yfjY Escherichia coli BW2952 CP4-57 prophage; putative DNA repair protein YP_002927594.1 2660220 D 595496 CDS YP_002927595.1 238901799 7953114 2660711..2660911 1 NC_012759.1 MG1655 equivalent: b4548; hypothetical protein 2660911 ypjJ 7953114 ypjJ Escherichia coli BW2952 hypothetical protein YP_002927595.1 2660711 D 595496 CDS YP_002927596.1 238901800 7955536 2660949..2661266 1 NC_012759.1 MG1655 equivalent: b2645; CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system 2661266 yfjZ 7955536 yfjZ Escherichia coli BW2952 CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system YP_002927596.1 2660949 D 595496 CDS YP_002927597.1 238901801 7953109 2661287..2661616 1 NC_012759.1 MG1655 equivalent: b2646; CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system 2661616 ypjF 7953109 ypjF Escherichia coli BW2952 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system YP_002927597.1 2661287 D 595496 CDS YP_002927598.1 238901802 7952204 complement(2661980..2666560) 1 NC_012759.1 MG1655 equivalent: b2647; adhesin-like autotransporter 2666560 ypjA 7952204 ypjA Escherichia coli BW2952 adhesin-like autotransporter YP_002927598.1 2661980 R 595496 CDS YP_002927599.1 238901803 7952061 2672819..2673796 1 NC_012759.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2673796 csiD 7952061 csiD Escherichia coli BW2952 hypothetical protein YP_002927599.1 2672819 D 595496 CDS YP_002927600.1 238901804 7955502 2673816..2675084 1 NC_012759.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2675084 ygaF 7955502 ygaF Escherichia coli BW2952 hydroxyglutarate oxidase YP_002927600.1 2673816 D 595496 CDS YP_002927601.1 238901805 7954846 2675107..2676555 1 NC_012759.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2676555 gabD 7954846 gabD Escherichia coli BW2952 succinate-semialdehyde dehydrogenase I YP_002927601.1 2675107 D 595496 CDS YP_002927602.1 238901806 7956080 2676569..2677849 1 NC_012759.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2677849 gabT 7956080 gabT Escherichia coli BW2952 4-aminobutyrate aminotransferase YP_002927602.1 2676569 D 595496 CDS YP_002927603.1 238901807 7952330 2678087..2679487 1 NC_012759.1 MG1655 equivalent: b2663; gamma-aminobutyrate transporter 2679487 gabP 7952330 gabP Escherichia coli BW2952 gamma-aminobutyrate transporter YP_002927603.1 2678087 D 595496 CDS YP_002927604.1 238901808 7953763 2679508..2680170 1 NC_012759.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2680170 csiR 7953763 csiR Escherichia coli BW2952 DNA-binding transcriptional regulator CsiR YP_002927604.1 2679508 D 595496 CDS YP_002927605.1 238901809 7953421 complement(2680171..2680620) 1 NC_012759.1 MG1655 equivalent: b2665; LysM domain/BON superfamily protein 2680620 ygaU 7953421 ygaU Escherichia coli BW2952 LysM domain/BON superfamily protein YP_002927605.1 2680171 R 595496 CDS YP_002927606.1 238901810 7955395 complement(2680704..2680862) 1 NC_012759.1 MG1655 equivalent: b2666; hypothetical protein 2680862 yqaE 7955395 yqaE Escherichia coli BW2952 hypothetical protein YP_002927606.1 2680704 R 595496 CDS YP_002927607.1 238901811 7955140 2681045..2681344 1 NC_012759.1 MG1655 equivalent: b2667; putative DNA-binding transcriptional regulator 2681344 ygaV 7955140 ygaV Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927607.1 2681045 D 595496 CDS YP_002927608.1 238901812 7954808 2681354..2681878 1 NC_012759.1 MG1655 equivalent: b2668; putative inner membrane protein with hydrolase activity 2681878 ygaP 7954808 ygaP Escherichia coli BW2952 putative inner membrane protein with hydrolase activity YP_002927608.1 2681354 D 595496 CDS YP_002927609.1 238901813 7955077 complement(2681925..2682329) 1 NC_012759.1 MG1655 equivalent: b2669; DNA binding protein 2682329 stpA 7955077 stpA Escherichia coli BW2952 DNA binding protein YP_002927609.1 2681925 R 595496 CDS YP_002927610.1 238901814 7953299 2682998..2683447 1 NC_012759.1 MG1655 equivalent: b2670; putative inner membrane protein 2683447 ygaW 7953299 ygaW Escherichia coli BW2952 putative inner membrane protein YP_002927610.1 2682998 D 595496 CDS YP_002927611.1 238901815 7955058 complement(2683484..2683828) 1 NC_012759.1 MG1655 equivalent: b2671; hypothetical protein 2683828 ygaC 7955058 ygaC Escherichia coli BW2952 hypothetical protein YP_002927611.1 2683484 R 595496 CDS YP_002927612.1 238901816 7955396 2683968..2684309 1 NC_012759.1 MG1655 equivalent: b2672; hypothetical protein 2684309 ygaM 7955396 ygaM Escherichia coli BW2952 hypothetical protein YP_002927612.1 2683968 D 595496 CDS YP_002927613.1 238901817 7955503 2684557..2684802 1 NC_012759.1 MG1655 equivalent: b2673; glutaredoxin-like protein 2684802 nrdH 7955503 nrdH Escherichia coli BW2952 glutaredoxin-like protein YP_002927613.1 2684557 D 595496 CDS YP_002927614.1 238901818 7953838 2684799..2685209 1 NC_012759.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2685209 nrdI 7953838 nrdI Escherichia coli BW2952 ribonucleotide reductase stimulatory protein YP_002927614.1 2684799 D 595496 CDS YP_002927615.1 238901819 7955811 2685182..2687326 1 NC_012759.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2687326 nrdE 7955811 nrdE Escherichia coli BW2952 ribonucleotide-diphosphate reductase subunit alpha YP_002927615.1 2685182 D 595496 CDS YP_002927616.1 238901820 7955969 2687336..2688295 1 NC_012759.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2688295 nrdF 7955969 nrdF Escherichia coli BW2952 ribonucleotide-diphosphate reductase subunit beta YP_002927616.1 2687336 D 595496 CDS YP_002927617.1 238901821 7955970 2688649..2689851 1 NC_012759.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2689851 proV 7955970 proV Escherichia coli BW2952 glycine betaine transporter ATP-binding subunit YP_002927617.1 2688649 D 595496 CDS YP_002927618.1 238901822 7953855 2689844..2690908 1 NC_012759.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2690908 proW 7953855 proW Escherichia coli BW2952 glycine betaine transporter membrane protein YP_002927618.1 2689844 D 595496 CDS YP_002927619.1 238901823 7953856 2690966..2691958 1 NC_012759.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2691958 proX 7953856 proX Escherichia coli BW2952 glycine betaine transporter periplasmic subunit YP_002927619.1 2690966 D 595496 CDS YP_002927620.1 238901824 7953857 2693451..2694188 1 NC_012759.1 MG1655 equivalent: b2682; putative transporter 2694188 ygaZ 7953857 ygaZ Escherichia coli BW2952 putative transporter YP_002927620.1 2693451 D 595496 CDS YP_002927621.1 238901825 7955696 2694178..2694513 1 NC_012759.1 MG1655 equivalent: b2683; hypothetical protein 2694513 ygaH 7955696 ygaH Escherichia coli BW2952 hypothetical protein YP_002927621.1 2694178 D 595496 CDS YP_002927622.1 238901826 7955059 2694604..2695134 1 NC_012759.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2695134 mprA 7955059 mprA Escherichia coli BW2952 transcriptional repressor MprA YP_002927622.1 2694604 D 595496 CDS YP_002927623.1 238901827 7953473 2695261..2696433 1 NC_012759.1 MG1655 equivalent: b2685; multidrug efflux system 2696433 emrA 7953473 emrA Escherichia coli BW2952 multidrug efflux system YP_002927623.1 2695261 D 595496 CDS YP_002927624.1 238901828 7954298 2696450..2697988 1 NC_012759.1 MG1655 equivalent: b2686; multidrug efflux system protein 2697988 emrB 7954298 emrB Escherichia coli BW2952 multidrug efflux system protein YP_002927624.1 2696450 D 595496 CDS YP_002927625.1 238901829 7954303 complement(2698052..2698567) 1 NC_012759.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2698567 luxS 7954303 luxS Escherichia coli BW2952 S-ribosylhomocysteinase YP_002927625.1 2698052 R 595496 CDS YP_002927626.1 238901830 7952189 complement(2698717..2700273) 1 NC_012759.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 2700273 gshA 7952189 gshA Escherichia coli BW2952 glutamate--cysteine ligase YP_002927626.1 2698717 R 595496 CDS YP_002927627.1 238901831 7953769 complement(2700346..2700774) 1 NC_012759.1 MG1655 equivalent: b2689; hypothetical protein 2700774 yqaA 7953769 yqaA Escherichia coli BW2952 hypothetical protein YP_002927627.1 2700346 R 595496 CDS YP_002927628.1 238901832 7952679 complement(2700771..2701337) 1 NC_012759.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 2701337 yqaB 7952679 yqaB Escherichia coli BW2952 fructose-1-phosphatase YP_002927628.1 2700771 R 595496 CDS YP_002927629.1 238901833 7952066 complement(2702795..2702980) 1 NC_012759.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 2702980 csrA 7952066 csrA Escherichia coli BW2952 carbon storage regulator YP_002927629.1 2702795 R 595496 CDS YP_002927630.1 238901834 7954561 complement(2703215..2705845) 1 NC_012759.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2705845 alaS 7954561 alaS Escherichia coli BW2952 alanyl-tRNA synthetase YP_002927630.1 2703215 R 595496 CDS YP_002927631.1 238901835 7952440 complement(2705973..2706473) 1 NC_012759.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2706473 recX 7952440 recX Escherichia coli BW2952 recombination regulator RecX YP_002927631.1 2705973 R 595496 CDS YP_002927632.1 238901836 7955934 complement(2706542..2707603) 1 NC_012759.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2707603 recA 7955934 recA Escherichia coli BW2952 recombinase A YP_002927632.1 2706542 R 595496 CDS YP_002927633.1 238901837 7953332 complement(2707683..2708180) 1 NC_012759.1 MG1655 equivalent: b2700; competence damage-inducible protein A 2708180 ygaD 7953332 ygaD Escherichia coli BW2952 competence damage-inducible protein A YP_002927633.1 2707683 R 595496 CDS YP_002927634.1 238901838 7952854 complement(2708325..2709410) 1 NC_012759.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 2709410 mltB 7952854 mltB Escherichia coli BW2952 murein hydrolase B YP_002927634.1 2708325 R 595496 CDS YP_002927635.1 238901839 7954240 2709666..2710229 1 NC_012759.1 MG1655 equivalent: b2702; glucitol/sorbitol-specific enzyme IIC component of PTS 2710229 srlA 7954240 srlA Escherichia coli BW2952 glucitol/sorbitol-specific enzyme IIC component of PTS YP_002927635.1 2709666 D 595496 CDS YP_002927636.1 238901840 7953795 2710226..2711185 1 NC_012759.1 MG1655 equivalent: b2703; glucitol/sorbitol-specific enzyme IIB component of PTS 2711185 srlE 7953795 srlE Escherichia coli BW2952 glucitol/sorbitol-specific enzyme IIB component of PTS YP_002927636.1 2710226 D 595496 CDS YP_002927637.1 238901841 7953794 2711196..2711567 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2711567 srlB 7953794 srlB Escherichia coli BW2952 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_002927637.1 2711196 D 595496 CDS YP_002927638.1 238901842 7953793 2711571..2712350 1 NC_012759.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2712350 srlD 7953793 srlD Escherichia coli BW2952 sorbitol-6-phosphate dehydrogenase YP_002927638.1 2711571 D 595496 CDS YP_002927639.1 238901843 7956058 2712455..2712814 1 NC_012759.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2712814 gutM 7956058 gutM Escherichia coli BW2952 DNA-binding transcriptional activator GutM YP_002927639.1 2712455 D 595496 CDS YP_002927640.1 238901844 7953390 2712881..2713654 1 NC_012759.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2713654 srlR 7953390 srlR Escherichia coli BW2952 DNA-binding transcriptional repressor SrlR YP_002927640.1 2712881 D 595496 CDS YP_002927641.1 238901845 7953484 2713647..2714612 1 NC_012759.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2714612 gutQ 7953484 gutQ Escherichia coli BW2952 D-arabinose 5-phosphate isomerase YP_002927641.1 2713647 D 595496 CDS YP_002927642.1 238901846 7955319 complement(2714609..2716123) 1 NC_012759.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 2716123 norR 7955319 norR Escherichia coli BW2952 anaerobic nitric oxide reductase transcriptional regulator YP_002927642.1 2714609 R 595496 CDS YP_002927643.1 238901847 7953369 2716310..2717749 1 NC_012759.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2717749 norV 7953369 norV Escherichia coli BW2952 anaerobic nitric oxide reductase flavorubredoxin YP_002927643.1 2716310 D 595496 CDS YP_002927644.1 238901848 7953612 2717746..2718879 1 NC_012759.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2718879 norW 7953612 norW Escherichia coli BW2952 nitric oxide reductase YP_002927644.1 2717746 D 595496 CDS YP_002927645.1 238901849 7954355 complement(2719007..2721259) 1 NC_012759.1 MG1655 equivalent: b2712; carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases 2721259 hypF 7954355 hypF Escherichia coli BW2952 carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases YP_002927645.1 2719007 R 595496 CDS YP_002927646.1 238901850 7952591 complement(2721412..2721939) 1 NC_012759.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 2721939 hydN 7952591 hydN Escherichia coli BW2952 electron transport protein HydN YP_002927646.1 2721412 R 595496 CDS YP_002927647.1 238901851 7953617 complement(2722088..2723101) 1 NC_012759.1 MG1655 equivalent: b2714; DNA-binding transcriptional repressor 2723101 ascG 7953617 ascG Escherichia coli BW2952 DNA-binding transcriptional repressor YP_002927647.1 2722088 R 595496 CDS YP_002927648.1 238901852 7953455 2723358..2724815 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 2724815 ascF 7953455 ascF Escherichia coli BW2952 PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_002927648.1 2723358 D 595496 CDS YP_002927649.1 238901853 7953660 2724824..2726248 1 NC_012759.1 MG1655 equivalent: b2716; cryptic 6-phospho-beta-glucosidase 2726248 ascB 7953660 ascB Escherichia coli BW2952 cryptic 6-phospho-beta-glucosidase YP_002927649.1 2724824 D 595496 CDS YP_002927650.1 238901854 7953165 complement(2726407..2726877) 1 NC_012759.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 2726877 hycI 7953165 hycI Escherichia coli BW2952 hydrogenase 3 maturation protease YP_002927650.1 2726407 R 595496 CDS YP_002927651.1 238901855 7955777 complement(2726870..2727280) 1 NC_012759.1 MG1655 equivalent: b2718; protein required for maturation of hydrogenase 3 2727280 hycH 7955777 hycH Escherichia coli BW2952 protein required for maturation of hydrogenase 3 YP_002927651.1 2726870 R 595496 CDS YP_002927652.1 238901856 7955804 complement(2727277..2728044) 1 NC_012759.1 MG1655 equivalent: b2719; hydrogenase 3 and formate hydrogenase complex, HycG subunit 2728044 hycG 7955804 hycG Escherichia coli BW2952 hydrogenase 3 and formate hydrogenase complex, HycG subunit YP_002927652.1 2727277 R 595496 CDS YP_002927653.1 238901857 7953943 complement(2728044..2728586) 1 NC_012759.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 2728586 hycF 7953943 hycF Escherichia coli BW2952 formate hydrogenlyase complex iron-sulfur subunit YP_002927653.1 2728044 R 595496 CDS YP_002927654.1 238901858 7953625 complement(2728596..2730305) 1 NC_012759.1 MG1655 equivalent: b2721; hydrogenase 3, large subunit 2730305 hycE 7953625 hycE Escherichia coli BW2952 hydrogenase 3, large subunit YP_002927654.1 2728596 R 595496 CDS YP_002927655.1 238901859 7953945 complement(2730323..2731246) 1 NC_012759.1 MG1655 equivalent: b2722; hydrogenase 3, membrane subunit 2731246 hycD 7953945 hycD Escherichia coli BW2952 hydrogenase 3, membrane subunit YP_002927655.1 2730323 R 595496 CDS YP_002927656.1 238901860 7953946 complement(2731249..2733075) 1 NC_012759.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 2733075 hycC 7953946 hycC Escherichia coli BW2952 formate hydrogenlyase subunit 3 YP_002927656.1 2731249 R 595496 CDS YP_002927657.1 238901861 7953947 complement(2733072..2733683) 1 NC_012759.1 MG1655 equivalent: b2724; hydrogenase 3, Fe-S subunit 2733683 hycB 7953947 hycB Escherichia coli BW2952 hydrogenase 3, Fe-S subunit YP_002927657.1 2733072 R 595496 CDS YP_002927658.1 238901862 7953944 complement(2733808..2734269) 1 NC_012759.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 2734269 hycA 7953944 hycA Escherichia coli BW2952 formate hydrogenlyase regulatory protein HycA YP_002927658.1 2733808 R 595496 CDS YP_002927659.1 238901863 7955925 2734481..2734831 1 NC_012759.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 2734831 hypA 7955925 hypA Escherichia coli BW2952 hydrogenase nickel incorporation protein YP_002927659.1 2734481 D 595496 CDS YP_002927660.1 238901864 7955796 2734835..2735707 1 NC_012759.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2735707 hypB 7955796 hypB Escherichia coli BW2952 hydrogenase nickel incorporation protein HypB YP_002927660.1 2734835 D 595496 CDS YP_002927661.1 238901865 7953877 2735698..2735970 1 NC_012759.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2735970 hypC 7953877 hypC Escherichia coli BW2952 hydrogenase assembly chaperone YP_002927661.1 2735698 D 595496 CDS YP_002927662.1 238901866 7955806 2735970..2737091 1 NC_012759.1 MG1655 equivalent: b2729; hydrogenase maturation protein 2737091 hypD 7955806 hypD Escherichia coli BW2952 hydrogenase maturation protein YP_002927662.1 2735970 D 595496 CDS YP_002927663.1 238901867 7955805 2737130..2738098 1 NC_012759.1 MG1655 equivalent: b2730; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 2738098 hypE 7955805 hypE Escherichia coli BW2952 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein YP_002927663.1 2737130 D 595496 CDS YP_002927664.1 238901868 7952592 2738172..2740250 1 NC_012759.1 MG1655 equivalent: b2731; DNA-binding transcriptional activator 2740250 fhlA 7952592 fhlA Escherichia coli BW2952 DNA-binding transcriptional activator YP_002927664.1 2738172 D 595496 CDS YP_002927665.1 238901869 7953380 complement(2740287..2740640) 1 NC_012759.1 MG1655 equivalent: b2732; hypothetical protein 2740640 ygbA 7953380 ygbA Escherichia coli BW2952 hypothetical protein YP_002927665.1 2740287 R 595496 CDS YP_002927666.1 238901870 7955397 2740927..2743488 1 NC_012759.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2743488 mutS 7955397 mutS Escherichia coli BW2952 DNA mismatch repair protein MutS YP_002927666.1 2740927 D 595496 CDS YP_002927667.1 238901871 7954254 2743594..2744250 1 NC_012759.1 MG1655 equivalent: b2734; serine/threonine-specific protein phosphatase 2 2744250 pphB 7954254 pphB Escherichia coli BW2952 serine/threonine-specific protein phosphatase 2 YP_002927667.1 2743594 D 595496 CDS YP_002927668.1 238901872 7956035 complement(2744301..2745098) 1 NC_012759.1 MG1655 equivalent: b2735; putative DNA-binding transcriptional regulator 2745098 ygbI 7956035 ygbI Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927668.1 2744301 R 595496 CDS YP_002927669.1 238901873 7954773 2745264..2746172 1 NC_012759.1 MG1655 equivalent: b2736; putative dehydrogenase, with NAD(P)-binding Rossmann-fold domain 2746172 ygbJ 7954773 ygbJ Escherichia coli BW2952 putative dehydrogenase, with NAD(P)-binding Rossmann-fold domain YP_002927669.1 2745264 D 595496 CDS YP_002927670.1 238901874 7954717 2746169..2747335 1 NC_012759.1 MG1655 equivalent: b2737; hypothetical protein 2747335 ygbK 7954717 ygbK Escherichia coli BW2952 hypothetical protein YP_002927670.1 2746169 D 595496 CDS YP_002927671.1 238901875 7953004 2747427..2748065 1 NC_012759.1 MG1655 equivalent: b2738; putative aldolase 2748065 ygbL 7953004 ygbL Escherichia coli BW2952 putative aldolase YP_002927671.1 2747427 D 595496 CDS YP_002927672.1 238901876 7954694 2748070..2748846 1 NC_012759.1 MG1655 equivalent: b2739; hypothetical protein 2748846 ygbM 7954694 ygbM Escherichia coli BW2952 hypothetical protein YP_002927672.1 2748070 D 595496 CDS YP_002927673.1 238901877 7953005 2748935..2750299 1 NC_012759.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 2750299 ygbN 7953005 ygbN Escherichia coli BW2952 inner membrane permease YgbN YP_002927673.1 2748935 D 595496 CDS YP_002927674.1 238901878 7955697 complement(2750393..2751385) 1 NC_012759.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 2751385 rpoS 7955697 rpoS Escherichia coli BW2952 RNA polymerase sigma factor RpoS YP_002927674.1 2750393 R 595496 CDS YP_002927675.1 238901879 7955992 complement(2751448..2752587) 1 NC_012759.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 2752587 nlpD 7955992 nlpD Escherichia coli BW2952 lipoprotein NlpD YP_002927675.1 2751448 R 595496 CDS YP_002927676.1 238901880 7955199 complement(2752727..2753353) 1 NC_012759.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 2753353 pcm 7955199 pcm Escherichia coli BW2952 protein-L-isoaspartate O-methyltransferase YP_002927676.1 2752727 R 595496 CDS YP_002927677.1 238901881 7954160 complement(2753347..2754108) 1 NC_012759.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 2754108 surE 7954160 surE Escherichia coli BW2952 stationary phase survival protein SurE YP_002927677.1 2753347 R 595496 CDS YP_002927678.1 238901882 7952584 complement(2754089..2755138) 1 NC_012759.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 2755138 truD 7952584 truD Escherichia coli BW2952 tRNA pseudouridine synthase D YP_002927678.1 2754089 R 595496 CDS YP_002927679.1 238901883 7955819 complement(2755135..2755614) 1 NC_012759.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2755614 ispF 7955819 ispF Escherichia coli BW2952 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002927679.1 2755135 R 595496 CDS YP_002927680.1 238901884 7952254 complement(2755614..2756324) 1 NC_012759.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2756324 ispD 7952254 ispD Escherichia coli BW2952 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002927680.1 2755614 R 595496 CDS YP_002927681.1 238901885 7952331 complement(2756343..2756654) 1 NC_012759.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 2756654 ftsB 7952331 ftsB Escherichia coli BW2952 cell division protein FtsB YP_002927681.1 2756343 R 595496 CDS YP_002927682.1 238901886 7952616 complement(2756848..2757171) 1 NC_012759.1 MG1655 equivalent: b2749; hypothetical protein 2757171 ygbE 7952616 ygbE Escherichia coli BW2952 hypothetical protein YP_002927682.1 2756848 R 595496 CDS YP_002927683.1 238901887 7952680 complement(2757221..2757826) 1 NC_012759.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 2757826 cysC 7952680 cysC Escherichia coli BW2952 adenylylsulfate kinase YP_002927683.1 2757221 R 595496 CDS YP_002927684.1 238901888 7952420 complement(2757826..2759253) 1 NC_012759.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 2759253 cysN 7952420 cysN Escherichia coli BW2952 sulfate adenylyltransferase subunit 1 YP_002927684.1 2757826 R 595496 CDS YP_002927685.1 238901889 7956088 complement(2759255..2760163) 1 NC_012759.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2760163 cysD 7956088 cysD Escherichia coli BW2952 sulfate adenylyltransferase subunit 2 YP_002927685.1 2759255 R 595496 CDS YP_002927686.1 238901890 7956089 2760415..2761452 1 NC_012759.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 2761452 iap 7956089 iap Escherichia coli BW2952 alkaline phosphatase isozyme conversion aminopeptidase YP_002927686.1 2760415 D 595496 CDS YP_002927687.1 238901891 7952472 complement(2762403..2762687) 1 NC_012759.1 MG1655 equivalent: b2754; hypothetical protein 2762687 ygbF 7952472 ygbF Escherichia coli BW2952 hypothetical protein YP_002927687.1 2762403 R 595496 CDS YP_002927688.1 238901892 7955398 complement(2762689..2763606) 1 NC_012759.1 MG1655 equivalent: b2755; hypothetical protein 2763606 ygbT 7955398 ygbT Escherichia coli BW2952 hypothetical protein YP_002927688.1 2762689 R 595496 CDS YP_002927689.1 238901893 7952855 complement(2763622..2764221) 1 NC_012759.1 MG1655 equivalent: b2756; hypothetical protein 2764221 ygcH 7952855 ygcH Escherichia coli BW2952 hypothetical protein YP_002927689.1 2763622 R 595496 CDS YP_002927690.1 238901894 7955399 complement(2764208..2764882) 1 NC_012759.1 MG1655 equivalent: b2757; hypothetical protein 2764882 ygcI 7955399 ygcI Escherichia coli BW2952 hypothetical protein YP_002927690.1 2764208 R 595496 CDS YP_002927691.1 238901895 7955400 complement(2764885..2765976) 1 NC_012759.1 MG1655 equivalent: b2758; hypothetical protein 2765976 ygcJ 7955400 ygcJ Escherichia coli BW2952 hypothetical protein YP_002927691.1 2764885 R 595496 CDS YP_002927692.1 238901896 7955401 complement(2765989..2766471) 1 NC_012759.1 MG1655 equivalent: b2759; hypothetical protein 2766471 ygcK 7955401 ygcK Escherichia coli BW2952 hypothetical protein YP_002927692.1 2765989 R 595496 CDS YP_002927693.1 238901897 7955402 complement(2766464..2767972) 1 NC_012759.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein 2767972 ygcL 7955402 ygcL Escherichia coli BW2952 hypothetical protein YP_002927693.1 2766464 R 595496 CDS YP_002927694.1 238901898 7955403 complement(2768387..2771053) 1 NC_012759.1 MG1655 equivalent: b2761; hypothetical protein 2771053 ygcB 7955403 ygcB Escherichia coli BW2952 hypothetical protein YP_002927694.1 2768387 R 595496 CDS YP_002927695.1 238901899 7953093 complement(2771412..2772146) 1 NC_012759.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2772146 cysH 7953093 cysH Escherichia coli BW2952 phosphoadenosine phosphosulfate reductase YP_002927695.1 2771412 R 595496 CDS YP_002927696.1 238901900 7952324 complement(2772221..2773933) 1 NC_012759.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 2773933 cysI 7952324 cysI Escherichia coli BW2952 sulfite reductase subunit beta YP_002927696.1 2772221 R 595496 CDS YP_002927697.1 238901901 7956095 complement(2773933..2775732) 1 NC_012759.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 2775732 cysJ 7956095 cysJ Escherichia coli BW2952 sulfite reductase subunit alpha YP_002927697.1 2773933 R 595496 CDS YP_002927698.1 238901902 7956094 2776048..2776413 1 NC_012759.1 MG1655 equivalent: b2765; 6-pyruvoyl tetrahydrobiopterin synthase 2776413 sscR 7956094 sscR Escherichia coli BW2952 6-pyruvoyl tetrahydrobiopterin synthase YP_002927698.1 2776048 D 595496 CDS YP_002927699.1 238901903 7952381 2776491..2777762 1 NC_012759.1 MG1655 equivalent: b2766; putative oxidoreductase with FAD/NAD(P)-binding domain 2777762 ygcN 7952381 ygcN Escherichia coli BW2952 putative oxidoreductase with FAD/NAD(P)-binding domain YP_002927699.1 2776491 D 595496 CDS YP_002927700.1 238901904 7955243 2777753..2778013 1 NC_012759.1 MG1655 equivalent: b2767; putative 4Fe-4S cluster-containing protein 2778013 ygcO 7955243 ygcO Escherichia coli BW2952 putative 4Fe-4S cluster-containing protein YP_002927700.1 2777753 D 595496 CDS YP_002927701.1 238901905 7954591 2778030..2778605 1 NC_012759.1 MG1655 equivalent: b2768; putative anti-terminator regulatory protein 2778605 ygcP 7954591 ygcP Escherichia coli BW2952 putative anti-terminator regulatory protein YP_002927701.1 2778030 D 595496 CDS YP_002927702.1 238901906 7954654 complement(2778753..2779613) 1 NC_012759.1 MG1655 equivalent: b2769; putative flavoprotein 2779613 ygcQ 7954654 ygcQ Escherichia coli BW2952 putative flavoprotein YP_002927702.1 2778753 R 595496 CDS YP_002927703.1 238901907 7954906 complement(2779610..2780389) 1 NC_012759.1 MG1655 equivalent: b2770; putative flavoprotein 2780389 ygcR 7954906 ygcR Escherichia coli BW2952 putative flavoprotein YP_002927703.1 2779610 R 595496 CDS YP_002927704.1 238901908 7954907 complement(2780367..2781704) 1 NC_012759.1 MG1655 equivalent: b2771; putative transporter 2781704 ygcS 7954907 ygcS Escherichia coli BW2952 putative transporter YP_002927704.1 2780367 R 595496 CDS YP_002927705.1 238901909 7955663 complement(2781798..2783252) 1 NC_012759.1 MG1655 equivalent: b4463; putative FAD containing dehydrogenase 2783252 ygcU 7955663 ygcU Escherichia coli BW2952 putative FAD containing dehydrogenase YP_002927705.1 2781798 R 595496 CDS YP_002927706.1 238901910 7954866 complement(2783322..2784107) 1 NC_012759.1 MG1655 equivalent: b2774; putative deoxygluconate dehydrogenase 2784107 ygcW 7954866 ygcW Escherichia coli BW2952 putative deoxygluconate dehydrogenase YP_002927706.1 2783322 R 595496 CDS YP_002927707.1 238901911 7954718 2784426..2785703 1 NC_012759.1 MG1655 equivalent: b2775; putative transporter 2785703 yqcE 7954718 yqcE Escherichia coli BW2952 putative transporter YP_002927707.1 2784426 D 595496 CDS YP_002927708.1 238901912 7955698 2785730..2787208 1 NC_012759.1 MG1655 equivalent: b2776; putative kinase 2787208 ygcE 7955698 ygcE Escherichia coli BW2952 putative kinase YP_002927708.1 2785730 D 595496 CDS YP_002927709.1 238901913 7955096 complement(2788581..2789252) 1 NC_012759.1 MG1655 equivalent: b2777; hypothetical protein 2789252 ygcF 7955096 ygcF Escherichia coli BW2952 hypothetical protein YP_002927709.1 2788581 R 595496 CDS YP_002927710.1 238901914 7952856 2789545..2790417 1 NC_012759.1 MG1655 equivalent: b2778; hypothetical protein 2790417 ygcG 7952856 ygcG Escherichia coli BW2952 hypothetical protein YP_002927710.1 2789545 D 595496 CDS YP_002927711.1 238901915 7955504 complement(2790477..2791775) 1 NC_012759.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2791775 eno 7955504 eno Escherichia coli BW2952 phosphopyruvate hydratase YP_002927711.1 2790477 R 595496 CDS YP_002927712.1 238901916 7953522 complement(2791863..2793500) 1 NC_012759.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2793500 pyrG 7953522 pyrG Escherichia coli BW2952 CTP synthetase YP_002927712.1 2791863 R 595496 CDS YP_002927713.1 238901917 7953173 complement(2793728..2794519) 1 NC_012759.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 2794519 mazG 7953173 mazG Escherichia coli BW2952 nucleoside triphosphate pyrophosphohydrolase YP_002927713.1 2793728 R 595496 CDS YP_002927714.1 238901918 7954412 complement(2794590..2794925) 1 NC_012759.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 2794925 chpA 7954412 chpA Escherichia coli BW2952 toxin ChpA YP_002927714.1 2794590 R 595496 CDS YP_002927715.1 238901919 7956160 complement(2794925..2795173) 1 NC_012759.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 2795173 chpR 7956160 chpR Escherichia coli BW2952 antitoxin MazE YP_002927715.1 2794925 R 595496 CDS YP_002927716.1 238901920 7952486 complement(2795251..2797257) 1 NC_012759.1 MG1655 equivalent: b2714; GTP diphosphokinase 2797257 relA 7952486 relA Escherichia coli BW2952 GTP diphosphokinase YP_002927716.1 2795251 R 595496 CDS YP_002927717.1 238901921 7953876 complement(2797242..2798147) 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 2798147 7953876 BWG_2520 Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002927717.1 2797242 R 595496 CDS YP_002927718.1 238901922 7956183 complement(2798105..2798470) 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 2798470 7956183 BWG_2521 Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002927718.1 2798105 R 595496 CDS YP_002927719.1 238901923 7952206 complement(2798869..2800170) 1 NC_012759.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 2800170 rumA 7952206 rumA Escherichia coli BW2952 23S rRNA 5-methyluridine methyltransferase YP_002927719.1 2798869 R 595496 CDS YP_002927720.1 238901924 7952242 2800227..2802983 1 NC_012759.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 2802983 barA 7952242 barA Escherichia coli BW2952 hybrid sensory histidine kinase BarA YP_002927720.1 2800227 D 595496 CDS YP_002927721.1 238901925 7953931 complement(2803215..2804555) 1 NC_012759.1 MG1655 equivalent: b2787; (D)-glucarate dehydratase 1 2804555 gudD 7953931 gudD Escherichia coli BW2952 (D)-glucarate dehydratase 1 YP_002927721.1 2803215 R 595496 CDS YP_002927722.1 238901926 7952217 complement(2804576..2805916) 1 NC_012759.1 MG1655 equivalent: b2788; putative glucarate dehydratase 2805916 gudX 7952217 gudX Escherichia coli BW2952 putative glucarate dehydratase YP_002927722.1 2804576 R 595496 CDS YP_002927723.1 238901927 7954917 complement(2805918..2807270) 1 NC_012759.1 MG1655 equivalent: b2789; putative D-glucarate transporter 2807270 gudP 7954917 gudP Escherichia coli BW2952 putative D-glucarate transporter YP_002927723.1 2805918 R 595496 CDS YP_002927724.1 238901928 7954720 complement(2807705..2808154) 1 NC_012759.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 2808154 yqcA 7954720 yqcA Escherichia coli BW2952 flavodoxin YP_002927724.1 2807705 R 595496 CDS YP_002927725.1 238901929 7954908 complement(2808172..2808954) 1 NC_012759.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 2808954 truC 7954908 truC Escherichia coli BW2952 tRNA pseudouridine synthase C YP_002927725.1 2808172 R 595496 CDS YP_002927726.1 238901930 7956201 complement(2808954..2809283) 1 NC_012759.1 MG1655 equivalent: b2792; hypothetical protein 2809283 yqcC 7956201 yqcC Escherichia coli BW2952 hypothetical protein YP_002927726.1 2808954 R 595496 CDS YP_002927727.1 238901931 7952090 complement(2809905..2810450) 1 NC_012759.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 2810450 syd 7952090 syd Escherichia coli BW2952 SecY interacting protein Syd YP_002927727.1 2809905 R 595496 CDS YP_002927728.1 238901932 7955404 2810518..2811366 1 NC_012759.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 2811366 queF 7955404 queF Escherichia coli BW2952 7-cyano-7-deazaguanine reductase YP_002927728.1 2810518 D 595496 CDS YP_002927729.1 238901933 7952385 2811478..2812842 1 NC_012759.1 MG1655 equivalent: b2795; hypothetical protein 2812842 ygdH 7952385 ygdH Escherichia coli BW2952 hypothetical protein YP_002927729.1 2811478 D 595496 CDS YP_002927730.1 238901934 7953006 2813399..2814688 1 NC_012759.1 MG1655 equivalent: b2796; putative serine transporter 2814688 sdaC 7953006 sdaC Escherichia coli BW2952 putative serine transporter YP_002927730.1 2813399 D 595496 CDS YP_002927731.1 238901935 7955590 2814746..2816113 1 NC_012759.1 MG1655 equivalent: b2797; L-serine deaminase II 2816113 sdaB 7955590 sdaB Escherichia coli BW2952 L-serine deaminase II YP_002927731.1 2814746 D 595496 CDS YP_002927732.1 238901936 7954171 2816135..2816980 1 NC_012759.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 2816980 xni 7954171 xni Escherichia coli BW2952 exonuclease IX YP_002927732.1 2816135 D 595496 CDS YP_002927733.1 238901937 7956064 complement(2817035..2818186) 1 NC_012759.1 MG1655 equivalent: b2799; L-1,2-propanediol oxidoreductase 2818186 fucO 7956064 fucO Escherichia coli BW2952 L-1,2-propanediol oxidoreductase YP_002927733.1 2817035 R 595496 CDS YP_002927734.1 238901938 7954106 complement(2818211..2818858) 1 NC_012759.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 2818858 fucA 7954106 fucA Escherichia coli BW2952 L-fuculose phosphate aldolase YP_002927734.1 2818211 R 595496 CDS YP_002927735.1 238901939 7954140 2819405..2820721 1 NC_012759.1 MG1655 equivalent: b2801; L-fucose transporter 2820721 fucP 7954140 fucP Escherichia coli BW2952 L-fucose transporter YP_002927735.1 2819405 D 595496 CDS YP_002927736.1 238901940 7954138 2820754..2822529 1 NC_012759.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2822529 fucI 7954138 fucI Escherichia coli BW2952 L-fucose isomerase YP_002927736.1 2820754 D 595496 CDS YP_002927737.1 238901941 7954136 2822608..2824056 1 NC_012759.1 MG1655 equivalent: b2803; L-fuculokinase 2824056 fucK 7954136 fucK Escherichia coli BW2952 L-fuculokinase YP_002927737.1 2822608 D 595496 CDS YP_002927738.1 238901942 7954139 2824058..2824480 1 NC_012759.1 MG1655 equivalent: b2804; L-fucose mutarotase 2824480 fucU 7954139 fucU Escherichia coli BW2952 L-fucose mutarotase YP_002927738.1 2824058 D 595496 CDS YP_002927739.1 238901943 7954137 2824538..2825269 1 NC_012759.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 2825269 fucR 7954137 fucR Escherichia coli BW2952 DNA-binding transcriptional activator FucR YP_002927739.1 2824538 D 595496 CDS YP_002927740.1 238901944 7953381 complement(2825313..2826413) 1 NC_012759.1 MG1655 equivalent: b2806; putative RNA 2'-O-ribose methyltransferase 2826413 ygdE 7953381 ygdE Escherichia coli BW2952 putative RNA 2'-O-ribose methyltransferase YP_002927740.1 2825313 R 595496 CDS YP_002927741.1 238901945 7955155 complement(2826406..2826801) 1 NC_012759.1 MG1655 equivalent: b2807; hypothetical protein 2826801 ygdD 7955155 ygdD Escherichia coli BW2952 hypothetical protein YP_002927741.1 2826406 R 595496 CDS YP_002927742.1 238901946 7952681 complement(2826820..2827737) 1 NC_012759.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 2827737 gcvA 7952681 gcvA Escherichia coli BW2952 DNA-binding transcriptional activator GcvA YP_002927742.1 2826820 R 595496 CDS YP_002927743.1 238901947 7952190 complement(2828088..2828315) 1 NC_012759.1 MG1655 equivalent: b2809; hypothetical protein 2828315 ygdI 7952190 ygdI Escherichia coli BW2952 hypothetical protein YP_002927743.1 2828088 R 595496 CDS YP_002927744.1 238901948 7955405 2828507..2829712 1 NC_012759.1 MG1655 equivalent: b2810; cysteine sulfinate desulfinase 2829712 csdA 7955405 csdA Escherichia coli BW2952 cysteine sulfinate desulfinase YP_002927744.1 2828507 D 595496 CDS YP_002927745.1 238901949 7953183 2829712..2830155 1 NC_012759.1 MG1655 equivalent: b2811; putative Fe-S metabolism protein 2830155 csdE 7953183 csdE Escherichia coli BW2952 putative Fe-S metabolism protein YP_002927745.1 2829712 D 595496 CDS YP_002927746.1 238901950 7954872 complement(2830206..2831012) 1 NC_012759.1 MG1655 equivalent: b2812; hypothetical protein 2831012 ygdL 7954872 ygdL Escherichia coli BW2952 hypothetical protein YP_002927746.1 2830206 R 595496 CDS YP_002927747.1 238901951 7952858 complement(2831251..2832348) 1 NC_012759.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 2832348 mltA 7952858 mltA Escherichia coli BW2952 murein transglycosylase A YP_002927747.1 2831251 R 595496 CDS YP_002927748.1 238901952 7952144 complement(2832927..2834180) 1 NC_012759.1 MG1655 equivalent: b2817; N-acetylmuramoyl-L-alanine amidase 2834180 amiC 7952144 amiC Escherichia coli BW2952 N-acetylmuramoyl-L-alanine amidase YP_002927748.1 2832927 R 595496 CDS YP_002927749.1 238901953 7954343 2834412..2835743 1 NC_012759.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 2835743 argA 7954343 argA Escherichia coli BW2952 N-acetylglutamate synthase YP_002927749.1 2834412 D 595496 CDS YP_002927750.1 238901954 7953654 complement(2835805..2837631) 1 NC_012759.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 2837631 recD 7953654 recD Escherichia coli BW2952 exonuclease V subunit alpha YP_002927750.1 2835805 R 595496 CDS YP_002927751.1 238901955 7953541 complement(2837631..2841173) 1 NC_012759.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 2841173 recB 7953541 recB Escherichia coli BW2952 exonuclease V subunit beta YP_002927751.1 2837631 R 595496 CDS YP_002927752.1 238901956 7953542 complement(2841166..2844054) 1 NC_012759.1 MG1655 equivalent: b2821; protease III 2844054 ptrA 7953542 ptrA Escherichia coli BW2952 protease III YP_002927752.1 2841166 R 595496 CDS YP_002927753.1 238901957 7955776 complement(2844230..2847598) 1 NC_012759.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 2847598 recC 7955776 recC Escherichia coli BW2952 exonuclease V subunit gamma YP_002927753.1 2844230 R 595496 CDS YP_002927754.1 238901958 7953543 complement(2847611..2847934) 1 NC_012759.1 MG1655 equivalent: b2823; hypothetical protein 2847934 ppdC 7953543 ppdC Escherichia coli BW2952 hypothetical protein YP_002927754.1 2847611 R 595496 CDS YP_002927755.1 238901959 7955406 complement(2847919..2848326) 1 NC_012759.1 MG1655 equivalent: b2824; hypothetical protein 2848326 ygdB 7955406 ygdB Escherichia coli BW2952 hypothetical protein YP_002927755.1 2847919 R 595496 CDS YP_002927756.1 238901960 7955407 complement(2848323..2848886) 1 NC_012759.1 MG1655 equivalent: b2825; hypothetical protein 2848886 ppdB 7955407 ppdB Escherichia coli BW2952 hypothetical protein YP_002927756.1 2848323 R 595496 CDS YP_002927757.1 238901961 7952859 complement(2848877..2849347) 1 NC_012759.1 MG1655 equivalent: b2826; hypothetical protein 2849347 ppdA 7952859 ppdA Escherichia coli BW2952 hypothetical protein YP_002927757.1 2848877 R 595496 CDS YP_002927758.1 238901962 7952860 complement(2849531..2850325) 1 NC_012759.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 2850325 thyA 7952860 thyA Escherichia coli BW2952 thymidylate synthase YP_002927758.1 2849531 R 595496 CDS YP_002927759.1 238901963 7956151 complement(2850332..2851207) 1 NC_012759.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2851207 lgt 7956151 lgt Escherichia coli BW2952 prolipoprotein diacylglyceryl transferase YP_002927759.1 2850332 R 595496 CDS YP_002927760.1 238901964 7954521 complement(2851358..2853604) 1 NC_012759.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 2853604 ptsP 7954521 ptsP Escherichia coli BW2952 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_002927760.1 2851358 R 595496 CDS YP_002927761.1 238901965 7953737 complement(2853617..2854147) 1 NC_012759.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 2854147 rppH 7953737 rppH Escherichia coli BW2952 dinucleoside polyphosphate hydrolase YP_002927761.1 2853617 R 595496 CDS YP_002927762.1 238901966 7954415 complement(2854500..2854646) 1 NC_012759.1 MG1655 equivalent: b4610; hypothetical protein 2854646 ygdT 7954415 ygdT Escherichia coli BW2952 hypothetical protein YP_002927762.1 2854500 R 595496 CDS YP_002927763.1 238901967 7953970 2854832..2855521 1 NC_012759.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 2855521 mutH 7953970 mutH Escherichia coli BW2952 DNA mismatch repair protein YP_002927763.1 2854832 D 595496 CDS YP_002927764.1 238901968 7954255 2855590..2856303 1 NC_012759.1 MG1655 equivalent: b2832; putative inner membrane protein 2856303 ygdQ 7954255 ygdQ Escherichia coli BW2952 putative inner membrane protein YP_002927764.1 2855590 D 595496 CDS YP_002927765.1 238901969 7955060 2856441..2856659 1 NC_012759.1 MG1655 equivalent: b2833; hypothetical protein 2856659 ygdR 7955060 ygdR Escherichia coli BW2952 hypothetical protein YP_002927765.1 2856441 D 595496 CDS YP_002927766.1 238901970 7955505 2856767..2857807 1 NC_012759.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 2857807 tas 7955505 tas Escherichia coli BW2952 putative aldo-keto reductase YP_002927766.1 2856767 D 595496 CDS YP_002927767.1 238901971 7955257 complement(2857839..2859032) 1 NC_012759.1 MG1655 equivalent: b2835; lysophospholipid transporter LplT 2859032 lplT 7955257 lplT Escherichia coli BW2952 lysophospholipid transporter LplT YP_002927767.1 2857839 R 595496 CDS YP_002927768.1 238901972 7955007 complement(2859025..2861184) 1 NC_012759.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 2861184 aas 7955007 aas Escherichia coli BW2952 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_002927768.1 2859025 R 595496 CDS YP_002927769.1 238901973 7952092 2861769..2862800 1 NC_012759.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 2862800 galR 7952092 galR Escherichia coli BW2952 DNA-binding transcriptional regulator GalR YP_002927769.1 2861769 D 595496 CDS YP_002927770.1 238901974 7953465 complement(2862807..2864069) 1 NC_012759.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 2864069 lysA 7953465 lysA Escherichia coli BW2952 diaminopimelate decarboxylase YP_002927770.1 2862807 R 595496 CDS YP_002927771.1 238901975 7953247 2864191..2865126 1 NC_012759.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 2865126 lysR 7953247 lysR Escherichia coli BW2952 LysR family transcriptional regulator YP_002927771.1 2864191 D 595496 CDS YP_002927772.1 238901976 7953422 complement(2865113..2865805) 1 NC_012759.1 MG1655 equivalent: b2840; putative racemase 2865805 ygeA 7953422 ygeA Escherichia coli BW2952 putative racemase YP_002927772.1 2865113 R 595496 CDS YP_002927773.1 238901977 7955555 complement(2865934..2867352) 1 NC_012759.1 MG1655 equivalent: b2841; arabinose transporter 2867352 araE 7955555 araE Escherichia coli BW2952 arabinose transporter YP_002927773.1 2865934 R 595496 CDS YP_002927774.1 238901978 7952492 complement(2867667..2868428) 1 NC_012759.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 2868428 kduD 7952492 kduD Escherichia coli BW2952 2-deoxy-D-gluconate 3-dehydrogenase YP_002927774.1 2867667 R 595496 CDS YP_002927775.1 238901979 7952257 complement(2868458..2869294) 1 NC_012759.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 2869294 kduI 7952257 kduI Escherichia coli BW2952 5-keto-4-deoxyuronate isomerase YP_002927775.1 2868458 R 595496 CDS YP_002927776.1 238901980 7954597 complement(2869581..2870762) 1 NC_012759.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 2870762 yqeF 7954597 yqeF Escherichia coli BW2952 acetyl-CoA acetyltransferase YP_002927776.1 2869581 R 595496 CDS YP_002927777.1 238901981 7954613 2871017..2872246 1 NC_012759.1 MG1655 equivalent: b2845; putative transporter 2872246 yqeG 7954613 yqeG Escherichia coli BW2952 putative transporter YP_002927777.1 2871017 D 595496 CDS YP_002927778.1 238901982 7955699 2872706..2873338 1 NC_012759.1 MG1655 equivalent: b2846; hypothetical protein 2873338 yqeH 7955699 yqeH Escherichia coli BW2952 hypothetical protein YP_002927778.1 2872706 D 595496 CDS YP_002927779.1 238901983 7953077 2873672..2874481 1 NC_012759.1 MG1655 equivalent: b2847; putative transcriptional regulator 2874481 yqeI 7953077 yqeI Escherichia coli BW2952 putative transcriptional regulator YP_002927779.1 2873672 D 595496 CDS YP_002927780.1 238901984 7955635 2874474..2874956 1 NC_012759.1 MG1655 equivalent: b2848; hypothetical protein 2874956 yqeJ 7955635 yqeJ Escherichia coli BW2952 hypothetical protein YP_002927780.1 2874474 D 595496 CDS YP_002927781.1 238901985 7955506 complement(2875105..2875530) 1 NC_012759.1 MG1655 equivalent: b2849; hypothetical protein 2875530 yqeK 7955506 yqeK Escherichia coli BW2952 hypothetical protein YP_002927781.1 2875105 R 595496 CDS YP_002927782.1 238901986 7955408 2876438..2876929 1 NC_012759.1 MG1655 equivalent: b2851; putative chaperone 2876929 ygeG 7955408 ygeG Escherichia coli BW2952 putative chaperone YP_002927782.1 2876438 D 595496 CDS YP_002927783.1 238901987 7954690 2877264..2878640 1 NC_012759.1 MG1655 equivalent: b2852; transcriptional regulator 2878640 ygeH 7954690 ygeH Escherichia coli BW2952 transcriptional regulator YP_002927783.1 2877264 D 595496 CDS YP_002927784.1 238901988 7955757 2878808..2879026 1 NC_012759.1 MG1655 equivalent: b2853; hypothetical protein 2879026 ygeI 7955757 ygeI Escherichia coli BW2952 hypothetical protein YP_002927784.1 2878808 D 595496 CDS YP_002927785.1 238901989 7955507 complement(2881542..2882447) 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 2882447 insD 7955507 insD Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002927785.1 2881542 R 595496 CDS YP_002927786.1 238901990 7954079 complement(2882405..2882770) 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 2882770 insC 7954079 insC Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002927786.1 2882405 R 595496 CDS YP_002927787.1 238901991 7952067 complement(2884306..2885061) 1 NC_012759.1 MG1655 equivalent: b2865; hypothetical protein 2885061 ygeR 7952067 ygeR Escherichia coli BW2952 hypothetical protein YP_002927787.1 2884306 R 595496 CDS YP_002927788.1 238901992 7956121 2885515..2887773 1 NC_012759.1 putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 2887773 xdhA 7956121 xdhA Escherichia coli BW2952 xanthine dehydrogenase subunit XdhA YP_002927788.1 2885515 D 595496 CDS YP_002927789.1 238901993 7956278 2887784..2888662 1 NC_012759.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 2888662 xdhB 7956278 xdhB Escherichia coli BW2952 xanthine dehydrogenase subunit XdhB YP_002927789.1 2887784 D 595496 CDS YP_002927790.1 238901994 7956276 2888659..2889138 1 NC_012759.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 2889138 xdhC 7956276 xdhC Escherichia coli BW2952 xanthine dehydrogenase subunit XdhC YP_002927790.1 2888659 D 595496 CDS YP_002927791.1 238901995 7956277 complement(2889178..2890956) 1 NC_012759.1 MG1655 equivalent: b2869; putative DNA-binding transcriptional regulator 2890956 ygeV 7956277 ygeV Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927791.1 2889178 R 595496 CDS YP_002927792.1 238901996 7954774 2891432..2892622 1 NC_012759.1 MG1655 equivalent: b2870; aspartate/ornithine carbamoyltransferase family protein 2892622 ygeW 7954774 ygeW Escherichia coli BW2952 aspartate/ornithine carbamoyltransferase family protein YP_002927792.1 2891432 D 595496 CDS YP_002927793.1 238901997 7953007 2892680..2893876 1 NC_012759.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 2893876 ygeX 7953007 ygeX Escherichia coli BW2952 diaminopropionate ammonia-lyase YP_002927793.1 2892680 D 595496 CDS YP_002927794.1 238901998 7952232 2893934..2895145 1 NC_012759.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 2895145 ygeY 7952232 ygeY Escherichia coli BW2952 peptidase YP_002927794.1 2893934 D 595496 CDS YP_002927795.1 238901999 7955285 2895198..2896583 1 NC_012759.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 2896583 hyuA 7955285 hyuA Escherichia coli BW2952 phenylhydantoinase YP_002927795.1 2895198 D 595496 CDS YP_002927796.1 238902000 7953498 2896631..2897563 1 NC_012759.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2897563 yqeA 7953498 yqeA Escherichia coli BW2952 carbamate kinase YP_002927796.1 2896631 D 595496 CDS YP_002927797.1 238902001 7954639 complement(2897784..2899409) 1 NC_012759.1 MG1655 equivalent: b2875; hypothetical protein 2899409 yqeB 7954639 yqeB Escherichia coli BW2952 hypothetical protein YP_002927797.1 2897784 R 595496 CDS YP_002927798.1 238902002 7953079 complement(2899457..2900227) 1 NC_012759.1 MG1655 equivalent: b2876; hypothetical protein 2900227 yqeC 7953079 yqeC Escherichia coli BW2952 hypothetical protein YP_002927798.1 2899457 R 595496 CDS YP_002927799.1 238902003 7952861 2900330..2900908 1 NC_012759.1 MG1655 equivalent: b2877; hypothetical protein 2900908 ygfJ 7952861 ygfJ Escherichia coli BW2952 hypothetical protein YP_002927799.1 2900330 D 595496 CDS YP_002927800.1 238902004 7953008 2901230..2904328 1 NC_012759.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 2904328 ygfK 7953008 ygfK Escherichia coli BW2952 putative selenate reductase subunit YgfK YP_002927800.1 2901230 D 595496 CDS YP_002927801.1 238902005 7955252 2904331..2905659 1 NC_012759.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 2905659 ssnA 7955252 ssnA Escherichia coli BW2952 putative chlorohydrolase/aminohydrolase YP_002927801.1 2904331 D 595496 CDS YP_002927802.1 238902006 7954693 2905710..2906489 1 NC_012759.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 2906489 ygfM 7954693 ygfM Escherichia coli BW2952 putative selenate reductase subunit YgfM YP_002927802.1 2905710 D 595496 CDS YP_002927803.1 238902007 7955237 2906486..2909356 1 NC_012759.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 2909356 xdhD 7955237 xdhD Escherichia coli BW2952 putative selenate reductase subunit YgfN YP_002927803.1 2906486 D 595496 CDS YP_002927804.1 238902008 7953735 2909521..2910921 1 NC_012759.1 MG1655 equivalent: b2882; putative transporter 2910921 ygfO 7953735 ygfO Escherichia coli BW2952 putative transporter YP_002927804.1 2909521 D 595496 CDS YP_002927805.1 238902009 7955700 2910936..2912255 1 NC_012759.1 Catalyzes the deamination of guanine; guanine deaminase 2912255 guaD 7955700 guaD Escherichia coli BW2952 guanine deaminase YP_002927805.1 2910936 D 595496 CDS YP_002927806.1 238902010 7953884 2912291..2913658 1 NC_012759.1 MG1655 equivalent: b4464; putative transporter 2913658 ygfQ 7953884 ygfQ Escherichia coli BW2952 putative transporter YP_002927806.1 2912291 D 595496 CDS YP_002927807.1 238902011 7955716 complement(2913694..2914182) 1 NC_012759.1 MG1655 equivalent: b2886; putative oxidoreductase, 4Fe-4S ferredoxin-type subunit 2914182 ygfS 7955716 ygfS Escherichia coli BW2952 putative oxidoreductase, 4Fe-4S ferredoxin-type subunit YP_002927807.1 2913694 R 595496 CDS YP_002927808.1 238902012 7955251 complement(2914182..2916101) 1 NC_012759.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 2916101 ygfT 7955251 ygfT Escherichia coli BW2952 putative oxidoreductase Fe-S binding subunit YP_002927808.1 2914182 R 595496 CDS YP_002927809.1 238902013 7953721 2916537..2917985 1 NC_012759.1 MG1655 equivalent: b2888; putative transporter 2917985 ygfU 7953721 ygfU Escherichia coli BW2952 putative transporter YP_002927809.1 2916537 D 595496 CDS YP_002927810.1 238902014 7955701 2918235..2918783 1 NC_012759.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2918783 idi 7955701 idi Escherichia coli BW2952 isopentenyl-diphosphate delta-isomerase YP_002927810.1 2918235 D 595496 CDS YP_002927811.1 238902015 7954054 complement(2918827..2920344) 1 NC_012759.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 2920344 lysS 7954054 lysS Escherichia coli BW2952 lysyl-tRNA synthetase YP_002927811.1 2918827 R 595496 CDS YP_002927812.1 238902016 7954183 complement(join(2920354..2921377,2921379..2921452)) 1 NC_012759.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 2921452 prfB 7954183 prfB Escherichia coli BW2952 peptide chain release factor 2 YP_002927812.1 2920354 R 595496 CDS YP_002927813.1 238902017 7954475 complement(2921543..2923276) 1 NC_012759.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 2923276 recJ 7954475 recJ Escherichia coli BW2952 ssDNA exonuclease RecJ YP_002927813.1 2921543 R 595496 CDS YP_002927814.1 238902018 7956065 complement(2923282..2923992) 1 NC_012759.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 2923992 dsbC 7956065 dsbC Escherichia coli BW2952 thiol:disulfide interchange protein DsbC YP_002927814.1 2923282 R 595496 CDS YP_002927815.1 238902019 7955791 complement(2924017..2924913) 1 NC_012759.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 2924913 xerD 7955791 xerD Escherichia coli BW2952 site-specific tyrosine recombinase XerD YP_002927815.1 2924017 R 595496 CDS YP_002927816.1 238902020 7956047 2925025..2925546 1 NC_012759.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 2925546 fldB 7956047 fldB Escherichia coli BW2952 flavodoxin FldB YP_002927816.1 2925025 D 595496 CDS YP_002927817.1 238902021 7953610 complement(2925586..2925993) 1 NC_012759.1 MG1655 equivalent: b2896; hypothetical protein 2925993 ygfX 7953610 ygfX Escherichia coli BW2952 hypothetical protein YP_002927817.1 2925586 R 595496 CDS YP_002927818.1 238902022 7955409 complement(2925974..2926240) 1 NC_012759.1 MG1655 equivalent: b2897; hypothetical protein 2926240 ygfY 7955409 ygfY Escherichia coli BW2952 hypothetical protein YP_002927818.1 2925974 R 595496 CDS YP_002927819.1 238902023 7952862 2926483..2927463 1 NC_012759.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 2927463 ygfZ 7952862 ygfZ Escherichia coli BW2952 putative global regulator YP_002927819.1 2926483 D 595496 CDS YP_002927820.1 238902024 7954909 complement(2927659..2928318) 1 NC_012759.1 MG1655 equivalent: b2899; putative oxidoreductase, inner membrane subunit 2928318 yqfA 7954909 yqfA Escherichia coli BW2952 putative oxidoreductase, inner membrane subunit YP_002927820.1 2927659 R 595496 CDS YP_002927821.1 238902025 7955254 complement(2928482..2928793) 1 NC_012759.1 MG1655 equivalent: b2900; hypothetical protein 2928793 yqfB 7955254 yqfB Escherichia coli BW2952 hypothetical protein YP_002927821.1 2928482 R 595496 CDS YP_002927822.1 238902026 7952863 2928832..2930271 1 NC_012759.1 MG1655 equivalent: b2901; 6-phospho-beta-glucosidase 2930271 bglA 7952863 bglA Escherichia coli BW2952 6-phospho-beta-glucosidase YP_002927822.1 2928832 D 595496 CDS YP_002927823.1 238902027 7952376 complement(2930328..2931071) 1 NC_012759.1 MG1655 equivalent: b2902; hypothetical protein 2931071 ygfF 7952376 ygfF Escherichia coli BW2952 hypothetical protein YP_002927823.1 2930328 R 595496 CDS YP_002927824.1 238902028 7955180 complement(2931338..2934211) 1 NC_012759.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 2934211 gcvP 7955180 gcvP Escherichia coli BW2952 glycine dehydrogenase YP_002927824.1 2931338 R 595496 CDS YP_002927825.1 238902029 7953860 complement(2934330..2934719) 1 NC_012759.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 2934719 gcvH 7953860 gcvH Escherichia coli BW2952 glycine cleavage system protein H YP_002927825.1 2934330 R 595496 CDS YP_002927826.1 238902030 7953859 complement(2934743..2935837) 1 NC_012759.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 2935837 gcvT 7953859 gcvT Escherichia coli BW2952 glycine cleavage system aminomethyltransferase T YP_002927826.1 2934743 R 595496 CDS YP_002927827.1 238902031 7952469 complement(2936285..2937487) 1 NC_012759.1 MG1655 equivalent: b2906; hypothetical protein 2937487 visC 7952469 visC Escherichia coli BW2952 hypothetical protein YP_002927827.1 2936285 R 595496 CDS YP_002927828.1 238902032 7955239 complement(2937510..2938688) 1 NC_012759.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 2938688 ubiH 7955239 ubiH Escherichia coli BW2952 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002927828.1 2937510 R 595496 CDS YP_002927829.1 238902033 7952265 complement(2938685..2940010) 1 NC_012759.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 2940010 pepP 7952265 pepP Escherichia coli BW2952 proline aminopeptidase P II YP_002927829.1 2938685 R 595496 CDS YP_002927830.1 238902034 7955767 complement(2940036..2940614) 1 NC_012759.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 2940614 ygfB 7955767 ygfB Escherichia coli BW2952 hypothetical protein YP_002927830.1 2940036 R 595496 CDS YP_002927831.1 238902035 7955410 2940782..2941111 1 NC_012759.1 MG1655 equivalent: b2910; Z-ring-associated protein 2941111 zapA 7955410 zapA Escherichia coli BW2952 Z-ring-associated protein YP_002927831.1 2940782 D 595496 CDS YP_002927832.1 238902036 7952191 2941411..2941959 1 NC_012759.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 2941959 ygfA 7952191 ygfA Escherichia coli BW2952 putative ligase YP_002927832.1 2941411 D 595496 CDS YP_002927833.1 238902037 7952192 complement(2942348..2943580) 1 NC_012759.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2943580 serA 7952192 serA Escherichia coli BW2952 D-3-phosphoglycerate dehydrogenase YP_002927833.1 2942348 R 595496 CDS YP_002927834.1 238902038 7953207 complement(2943836..2944495) 1 NC_012759.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2944495 rpiA 7953207 rpiA Escherichia coli BW2952 ribose-5-phosphate isomerase A YP_002927834.1 2943836 R 595496 CDS YP_002927835.1 238902039 7955973 2944923..2945816 1 NC_012759.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2945816 argP 7955973 argP Escherichia coli BW2952 chromosome replication initiation inhibitor protein YP_002927835.1 2944923 D 595496 CDS YP_002927836.1 238902040 7953400 2946020..2948164 1 NC_012759.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 2948164 scpA 7953400 scpA Escherichia coli BW2952 methylmalonyl-CoA mutase YP_002927836.1 2946020 D 595496 CDS YP_002927837.1 238902041 7954261 2948157..2949152 1 NC_012759.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 2949152 argK 7954261 argK Escherichia coli BW2952 arginine/ornithine transport system ATPase YP_002927837.1 2948157 D 595496 CDS YP_002927838.1 238902042 7954225 2949163..2949948 1 NC_012759.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 2949948 scpB 7954225 scpB Escherichia coli BW2952 methylmalonyl-CoA decarboxylase YP_002927838.1 2949163 D 595496 CDS YP_002927839.1 238902043 7954260 2949972..2951450 1 NC_012759.1 MG1655 equivalent: b2920; propionyl-CoA:succinate-CoA transferase 2951450 scpC 7954260 scpC Escherichia coli BW2952 propionyl-CoA:succinate-CoA transferase YP_002927839.1 2949972 D 595496 CDS YP_002927840.1 238902044 7955774 complement(2951447..2952343) 1 NC_012759.1 MG1655 equivalent: b2921; putative DNA-binding transcriptional regulator 2952343 ygfI 7955774 ygfI Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927840.1 2951447 R 595496 CDS YP_002927841.1 238902045 7954775 complement(2952510..2953250) 1 NC_012759.1 MG1655 equivalent: b2922; hypothetical protein 2953250 yggE 7954775 yggE Escherichia coli BW2952 hypothetical protein YP_002927841.1 2952510 R 595496 CDS YP_002927842.1 238902046 7952864 complement(2953343..2953978) 1 NC_012759.1 Involved in the export of arginine; arginine exporter protein 2953978 argO 7952864 argO Escherichia coli BW2952 arginine exporter protein YP_002927842.1 2953343 R 595496 CDS YP_002927843.1 238902047 7952494 complement(2954117..2954977) 1 NC_012759.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 2954977 mscS 7952494 mscS Escherichia coli BW2952 mechanosensitive channel MscS YP_002927843.1 2954117 R 595496 CDS YP_002927844.1 238902048 7954218 complement(2955335..2956414) 1 NC_012759.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2956414 fbaA 7954218 fbaA Escherichia coli BW2952 fructose-bisphosphate aldolase YP_002927844.1 2955335 R 595496 CDS YP_002927845.1 238902049 7953638 complement(2956629..2957792) 1 NC_012759.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2957792 pgk 7953638 pgk Escherichia coli BW2952 phosphoglycerate kinase YP_002927845.1 2956629 R 595496 CDS YP_002927846.1 238902050 7954533 complement(2957842..2958861) 1 NC_012759.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 2958861 epd 7954533 epd Escherichia coli BW2952 erythrose 4-phosphate dehydrogenase YP_002927846.1 2957842 R 595496 CDS YP_002927847.1 238902051 7953240 complement(2959146..2959859) 1 NC_012759.1 MG1655 equivalent: b2928; putative fructose transport system kinase 2959859 frcK 7953240 frcK Escherichia coli BW2952 putative fructose transport system kinase YP_002927847.1 2959146 R 595496 CDS YP_002927848.1 238902052 7953086 complement(2959856..2960365) 1 NC_012759.1 MG1655 equivalent: b2929; putative DNA-binding transcriptional regulator 2960365 yggD 7953086 yggD Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927848.1 2959856 R 595496 CDS YP_002927849.1 238902053 7954776 complement(2960387..2961352) 1 NC_012759.1 MG1655 equivalent: b2930; fructose-1,6-bisphosphatase II-like protein 2961352 yggF 7954776 yggF Escherichia coli BW2952 fructose-1,6-bisphosphatase II-like protein YP_002927849.1 2960387 R 595496 CDS YP_002927850.1 238902054 7954944 complement(2961349..2962626) 1 NC_012759.1 MG1655 equivalent: b4465; putative dehydrogenase 2962626 yggP 7954944 yggP Escherichia coli BW2952 putative dehydrogenase YP_002927850.1 2961349 R 595496 CDS YP_002927851.1 238902055 7954713 complement(2962641..2964029) 1 NC_012759.1 MG1655 equivalent: b2933; putative fused mannitol-specific PTS enzymes: IIB component/IIC component 2964029 cmtA 7954713 cmtA Escherichia coli BW2952 putative fused mannitol-specific PTS enzymes: IIB component/IIC component YP_002927851.1 2962641 R 595496 CDS YP_002927852.1 238902056 7954914 complement(2964057..2964500) 1 NC_012759.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; putative mannitol phosphotransferase subunit EIIA 2964500 cmtB 7954914 cmtB Escherichia coli BW2952 putative mannitol phosphotransferase subunit EIIA YP_002927852.1 2964057 R 595496 CDS YP_002927853.1 238902057 7955132 complement(2964814..2966805) 1 NC_012759.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2966805 tktA 7955132 tktA Escherichia coli BW2952 transketolase YP_002927853.1 2964814 R 595496 CDS YP_002927854.1 238902058 7956174 2967083..2967841 1 NC_012759.1 MG1655 equivalent: b2936; putative peptidase 2967841 yggG 7956174 yggG Escherichia coli BW2952 putative peptidase YP_002927854.1 2967083 D 595496 CDS YP_002927855.1 238902059 7955286 complement(2968047..2968967) 1 NC_012759.1 catalyzes the formation of putrescine from agmatine; agmatinase 2968967 speB 7955286 speB Escherichia coli BW2952 agmatinase YP_002927855.1 2968047 R 595496 CDS YP_002927856.1 238902060 7952434 complement(2969105..2971081) 1 NC_012759.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 2971081 speA 7952434 speA Escherichia coli BW2952 arginine decarboxylase YP_002927856.1 2969105 R 595496 CDS YP_002927857.1 238902061 7952579 complement(2971090..2971221) 1 NC_012759.1 MG1655 equivalent: b2939; hypothetical protein 2971221 yqgB 7952579 yqgB Escherichia coli BW2952 hypothetical protein YP_002927857.1 2971090 R 595496 CDS YP_002927858.1 238902062 7955411 2971357..2971572 1 NC_012759.1 MG1655 equivalent: b2940; hypothetical protein 2971572 yqgC 7955411 yqgC Escherichia coli BW2952 hypothetical protein YP_002927858.1 2971357 D 595496 CDS YP_002927859.1 238902063 7955508 complement(2971569..2971820) 1 NC_012759.1 MG1655 equivalent: b2941; putative inner membrane protein 2971820 yqgD 7955508 yqgD Escherichia coli BW2952 putative inner membrane protein YP_002927859.1 2971569 R 595496 CDS YP_002927860.1 238902064 7955008 2971876..2973030 1 NC_012759.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2973030 metK 7955008 metK Escherichia coli BW2952 S-adenosylmethionine synthetase YP_002927860.1 2971876 D 595496 CDS YP_002927861.1 238902065 7954242 2973454..2974848 1 NC_012759.1 MG1655 equivalent: b2943; D-galactose transporter 2974848 galP 7954242 galP Escherichia coli BW2952 D-galactose transporter YP_002927861.1 2973454 D 595496 CDS YP_002927862.1 238902066 7953243 2974925..2975422 1 NC_012759.1 MG1655 equivalent: b2944; hypothetical protein 2975422 yggI 7953243 yggI Escherichia coli BW2952 hypothetical protein YP_002927862.1 2974925 D 595496 CDS YP_002927863.1 238902067 7953009 2975517..2976224 1 NC_012759.1 MG1655 equivalent: b2945; DNA-specific endonuclease I 2976224 endA 7953009 endA Escherichia coli BW2952 DNA-specific endonuclease I YP_002927863.1 2975517 D 595496 CDS YP_002927864.1 238902068 7953492 2976304..2977035 1 NC_012759.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2977035 rsmE 7953492 rsmE Escherichia coli BW2952 16S ribosomal RNA methyltransferase RsmE YP_002927864.1 2976304 D 595496 CDS YP_002927865.1 238902069 7955509 2977048..2977998 1 NC_012759.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2977998 gshB 7955509 gshB Escherichia coli BW2952 glutathione synthetase YP_002927865.1 2977048 D 595496 CDS YP_002927866.1 238902070 7953840 2978107..2978670 1 NC_012759.1 MG1655 equivalent: b2948; hypothetical protein 2978670 yqgE 7953840 yqgE Escherichia coli BW2952 hypothetical protein YP_002927866.1 2978107 D 595496 CDS YP_002927867.1 238902071 7955510 2978670..2979086 1 NC_012759.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2979086 yqgF 7955510 yqgF Escherichia coli BW2952 Holliday junction resolvase-like protein YP_002927867.1 2978670 D 595496 CDS YP_002927868.1 238902072 7954946 complement(2979270..2980250) 1 NC_012759.1 MG1655 equivalent: b2950; putative transporter 2980250 yggR 7954946 yggR Escherichia coli BW2952 putative transporter YP_002927868.1 2979270 R 595496 CDS YP_002927869.1 238902073 7955664 2980268..2980972 1 NC_012759.1 MG1655 equivalent: b2951; putative enzyme 2980972 yggS 7955664 yggS Escherichia coli BW2952 putative enzyme YP_002927869.1 2980268 D 595496 CDS YP_002927870.1 238902074 7954847 2980990..2981556 1 NC_012759.1 MG1655 equivalent: b2952; putative inner membrane protein 2981556 yggT 7954847 yggT Escherichia coli BW2952 putative inner membrane protein YP_002927870.1 2980990 D 595496 CDS YP_002927871.1 238902075 7955061 2981553..2981843 1 NC_012759.1 MG1655 equivalent: b2953; hypothetical protein 2981843 yggU 7955061 yggU Escherichia coli BW2952 hypothetical protein YP_002927871.1 2981553 D 595496 CDS YP_002927872.1 238902076 7953010 2981851..2982444 1 NC_012759.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 2982444 rdgB 7953010 rdgB Escherichia coli BW2952 putative deoxyribonucleotide triphosphate pyrophosphatase YP_002927872.1 2981851 D 595496 CDS YP_002927873.1 238902077 7953270 2982437..2983573 1 NC_012759.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 2983573 yggW 7953270 yggW Escherichia coli BW2952 coproporphyrinogen III oxidase YP_002927873.1 2982437 D 595496 CDS YP_002927874.1 238902078 7955238 complement(2983728..2984735) 1 NC_012759.1 MG1655 equivalent: b2956; hypothetical protein 2984735 yggM 7955238 yggM Escherichia coli BW2952 hypothetical protein YP_002927874.1 2983728 R 595496 CDS YP_002927875.1 238902079 7952865 complement(2984852..2985898) 1 NC_012759.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 2985898 ansB 7952865 ansB Escherichia coli BW2952 L-asparaginase II YP_002927875.1 2984852 R 595496 CDS YP_002927876.1 238902080 7954493 complement(2986074..2986793) 1 NC_012759.1 MG1655 equivalent: b2958; hypothetical protein 2986793 yggN 7954493 yggN Escherichia coli BW2952 hypothetical protein YP_002927876.1 2986074 R 595496 CDS YP_002927877.1 238902081 7955412 complement(2986977..2987303) 1 NC_012759.1 MG1655 equivalent: b2959; hypothetical protein 2987303 yggL 7955412 yggL Escherichia coli BW2952 hypothetical protein YP_002927877.1 2986977 R 595496 CDS YP_002927878.1 238902082 7955413 complement(2987303..2988022) 1 NC_012759.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2988022 trmB 7955413 trmB Escherichia coli BW2952 tRNA (guanine-N(7)-)-methyltransferase YP_002927878.1 2987303 R 595496 CDS YP_002927879.1 238902083 7956198 2988183..2989235 1 NC_012759.1 MG1655 equivalent: b2961; adenine DNA glycosylase 2989235 mutY 7956198 mutY Escherichia coli BW2952 adenine DNA glycosylase YP_002927879.1 2988183 D 595496 CDS YP_002927880.1 238902084 7952418 2989263..2989538 1 NC_012759.1 MG1655 equivalent: b2962; hypothetical protein 2989538 yggX 7952418 yggX Escherichia coli BW2952 hypothetical protein YP_002927880.1 2989263 D 595496 CDS YP_002927881.1 238902085 7955810 2989603..2990682 1 NC_012759.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 2990682 mltC 7955810 mltC Escherichia coli BW2952 murein transglycosylase C YP_002927881.1 2989603 D 595496 CDS YP_002927882.1 238902086 7954241 2990884..2992140 1 NC_012759.1 MG1655 equivalent: b2964; nucleoside transporter 2992140 nupG 7954241 nupG Escherichia coli BW2952 nucleoside transporter YP_002927882.1 2990884 D 595496 CDS YP_002927883.1 238902087 7954411 complement(2992190..2994325) 1 NC_012759.1 MG1655 equivalent: b2965; ornithine decarboxylase 2994325 speC 7954411 speC Escherichia coli BW2952 ornithine decarboxylase YP_002927883.1 2992190 R 595496 CDS YP_002927884.1 238902088 7954430 2994723..2995430 1 NC_012759.1 MG1655 equivalent: b2966; putative inner membrane protein 2995430 yqgA 7954430 yqgA Escherichia coli BW2952 putative inner membrane protein YP_002927884.1 2994723 D 595496 CDS YP_002927885.1 238902089 7952145 complement(2995760..2996296) 1 NC_012759.1 MG1655 equivalent: b2968; putative general secretion pathway protein YghD 2996296 yghD 7952145 yghD Escherichia coli BW2952 putative general secretion pathway protein YghD YP_002927885.1 2995760 R 595496 CDS YP_002927886.1 238902090 7955584 complement(2998237..2998647) 1 NC_012759.1 MG1655 equivalent: b2971; hypothetical protein 2998647 yghG 7955584 yghG Escherichia coli BW2952 hypothetical protein YP_002927886.1 2998237 R 595496 CDS YP_002927887.1 238902091 7955414 complement(2998713..2999522) 1 NC_012759.1 MG1655 equivalent: b2972; bifunctional prepilin leader peptidase/ methylase 2999522 pppA 7955414 pppA Escherichia coli BW2952 bifunctional prepilin leader peptidase/ methylase YP_002927887.1 2998713 R 595496 CDS YP_002927888.1 238902092 7952571 complement(2999720..3004282) 1 NC_012759.1 MG1655 equivalent: b4466; putative inner membrane lipoprotein 3004282 yghJ 7952571 yghJ Escherichia coli BW2952 putative inner membrane lipoprotein YP_002927888.1 2999720 R 595496 CDS YP_002927889.1 238902093 7954981 complement(3004767..3006449) 1 NC_012759.1 MG1655 equivalent: b2975; glycolate transporter 3006449 glcA 7954981 glcA Escherichia coli BW2952 glycolate transporter YP_002927889.1 3004767 R 595496 CDS YP_002927890.1 238902094 7953869 complement(3006804..3008975) 1 NC_012759.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3008975 glcB 7953869 glcB Escherichia coli BW2952 malate synthase G YP_002927890.1 3006804 R 595496 CDS YP_002927891.1 238902095 7954201 complement(3008997..3009401) 1 NC_012759.1 MG1655 equivalent: b2977; hypothetical protein 3009401 glcG 7954201 glcG Escherichia coli BW2952 hypothetical protein YP_002927891.1 3008997 R 595496 CDS YP_002927892.1 238902096 7952866 complement(3009406..3010629) 1 NC_012759.1 MG1655 equivalent: b4467; glycolate oxidase iron-sulfur subunit 3010629 glcF 7952866 glcF Escherichia coli BW2952 glycolate oxidase iron-sulfur subunit YP_002927892.1 3009406 R 595496 CDS YP_002927893.1 238902097 7953867 complement(3010640..3011692) 1 NC_012759.1 MG1655 equivalent: b4468; glycolate oxidase FAD binding subunit 3011692 glcE 7953867 glcE Escherichia coli BW2952 glycolate oxidase FAD binding subunit YP_002927893.1 3010640 R 595496 CDS YP_002927894.1 238902098 7953866 complement(3011692..3013191) 1 NC_012759.1 MG1655 equivalent: b2979; glycolate oxidase subunit GlcD 3013191 glcD 7953866 glcD Escherichia coli BW2952 glycolate oxidase subunit GlcD YP_002927894.1 3011692 R 595496 CDS YP_002927895.1 238902099 7953868 3013442..3014206 1 NC_012759.1 MG1655 equivalent: b2980; DNA-binding transcriptional regulator GlcC 3014206 glcC 7953868 glcC Escherichia coli BW2952 DNA-binding transcriptional regulator GlcC YP_002927895.1 3013442 D 595496 CDS YP_002927896.1 238902100 7953432 3015348..3016364 1 NC_012759.1 MG1655 equivalent: b2982; IS5 transposase and trans-activator 3016364 insH 7953432 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002927896.1 3015348 D 595496 CDS YP_002927897.1 238902101 7954046 complement(3016511..3017578) 1 NC_012759.1 MG1655 equivalent: b2983; putative inner membrane protein 3017578 yghQ 7954046 yghQ Escherichia coli BW2952 putative inner membrane protein YP_002927897.1 3016511 R 595496 CDS YP_002927898.1 238902102 7955009 complement(3017624..3018382) 1 NC_012759.1 MG1655 equivalent: b2984; hypothetical protein 3018382 yghR 7955009 yghR Escherichia coli BW2952 hypothetical protein YP_002927898.1 3017624 R 595496 CDS YP_002927899.1 238902103 7955543 complement(3018414..3019127) 1 NC_012759.1 MG1655 equivalent: b2985; hypothetical protein 3019127 yghS 7955543 yghS Escherichia coli BW2952 hypothetical protein YP_002927899.1 3018414 R 595496 CDS YP_002927900.1 238902104 7955544 3019301..3019993 1 NC_012759.1 MG1655 equivalent: b2986; hypothetical protein 3019993 yghT 7955544 yghT Escherichia coli BW2952 hypothetical protein YP_002927900.1 3019301 D 595496 CDS YP_002927901.1 238902105 7955545 complement(3020042..3021541) 1 NC_012759.1 MG1655 equivalent: b2987; phosphate transporter 3021541 pitB 7955545 pitB Escherichia coli BW2952 phosphate transporter YP_002927901.1 3020042 R 595496 CDS YP_002927902.1 238902106 7954514 complement(3021833..3023692) 1 NC_012759.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3023692 gsp 7954514 gsp Escherichia coli BW2952 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_002927902.1 3021833 R 595496 CDS YP_002927903.1 238902107 7953684 3023897..3024763 1 NC_012759.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 3024763 yghU 7953684 yghU Escherichia coli BW2952 putative glutathione S-transferase YghU YP_002927903.1 3023897 D 595496 CDS YP_002927904.1 238902108 7955598 complement(3024886..3025134) 1 NC_012759.1 MG1655 equivalent: b2990; hydrogenase 2 accessory protein HypG 3025134 hybG 7955598 hybG Escherichia coli BW2952 hydrogenase 2 accessory protein HypG YP_002927904.1 3024886 R 595496 CDS YP_002927905.1 238902109 7953939 complement(3025147..3025488) 1 NC_012759.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3025488 hybF 7953939 hybF Escherichia coli BW2952 hydrogenase nickel incorporation protein HybF YP_002927905.1 3025147 R 595496 CDS YP_002927906.1 238902110 7955799 complement(3025481..3025969) 1 NC_012759.1 MG1655 equivalent: b2992; hydrogenase 2-specific chaperone 3025969 hybE 7955799 hybE Escherichia coli BW2952 hydrogenase 2-specific chaperone YP_002927906.1 3025481 R 595496 CDS YP_002927907.1 238902111 7953942 complement(3025962..3026456) 1 NC_012759.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3026456 hybD 7953942 hybD Escherichia coli BW2952 hydrogenase 2 maturation endopeptidase YP_002927907.1 3025962 R 595496 CDS YP_002927908.1 238902112 7955134 complement(3026456..3028159) 1 NC_012759.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3028159 hybC 7955134 hybC Escherichia coli BW2952 hydrogenase 2 large subunit YP_002927908.1 3026456 R 595496 CDS YP_002927909.1 238902113 7953940 complement(3028156..3029334) 1 NC_012759.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 3029334 hybB 7953940 hybB Escherichia coli BW2952 putative hydrogenase 2 b cytochrome subunit YP_002927909.1 3028156 R 595496 CDS YP_002927910.1 238902114 7954948 complement(3029324..3030310) 1 NC_012759.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3030310 hybA 7954948 hybA Escherichia coli BW2952 hydrogenase 2 protein HybA YP_002927910.1 3029324 R 595496 CDS YP_002927911.1 238902115 7953938 complement(3030313..3031431) 1 NC_012759.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3031431 hybO 7953938 hybO Escherichia coli BW2952 hydrogenase 2 small subunit YP_002927911.1 3030313 R 595496 CDS YP_002927912.1 238902116 7953941 complement(3031620..3031907) 1 NC_012759.1 MG1655 equivalent: b2998; hypothetical protein 3031907 yghW 7953941 yghW Escherichia coli BW2952 hypothetical protein YP_002927912.1 3031620 R 595496 CDS YP_002927913.1 238902117 7955415 3033067..3034107 1 NC_012759.1 MG1655 equivalent: b3001; aldo-keto reductase 3034107 yghZ 7955415 yghZ Escherichia coli BW2952 aldo-keto reductase YP_002927913.1 3033067 D 595496 CDS YP_002927914.1 238902118 7952445 complement(3034147..3034641) 1 NC_012759.1 MG1655 equivalent: b3002; hypothetical protein 3034641 yqhA 7952445 yqhA Escherichia coli BW2952 hypothetical protein YP_002927914.1 3034147 R 595496 CDS YP_002927915.1 238902119 7952682 3034832..3035716 1 NC_012759.1 MG1655 equivalent: b3003; oxidoreductase 3035716 yghA 7952682 yghA Escherichia coli BW2952 oxidoreductase YP_002927915.1 3034832 D 595496 CDS YP_002927916.1 238902120 7954929 complement(3035988..3036413) 1 NC_012759.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3036413 exbD 7954929 exbD Escherichia coli BW2952 biopolymer transport protein ExbD YP_002927916.1 3035988 R 595496 CDS YP_002927917.1 238902121 7954235 complement(3036420..3037154) 1 NC_012759.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3037154 exbB 7954235 exbB Escherichia coli BW2952 biopolymer transport protein ExbB YP_002927917.1 3036420 R 595496 CDS YP_002927918.1 238902122 7954236 3037406..3038593 1 NC_012759.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3038593 metC 7954236 metC Escherichia coli BW2952 cystathionine beta-lyase YP_002927918.1 3037406 D 595496 CDS YP_002927919.1 238902123 7953179 3038733..3039392 1 NC_012759.1 MG1655 equivalent: b3009; hypothetical protein 3039392 yghB 7953179 yghB Escherichia coli BW2952 hypothetical protein YP_002927919.1 3038733 D 595496 CDS YP_002927920.1 238902124 7952719 complement(3039432..3040388) 1 NC_012759.1 MG1655 equivalent: b3010; putative DNA-binding transcriptional regulator 3040388 yqhC 7952719 yqhC Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927920.1 3039432 R 595496 CDS YP_002927921.1 238902125 7954777 3040525..3041688 1 NC_012759.1 MG1655 equivalent: b3011; alcohol dehydrogenase 3041688 yqhD 7954777 yqhD Escherichia coli BW2952 alcohol dehydrogenase YP_002927921.1 3040525 D 595496 CDS YP_002927922.1 238902126 7952442 3041793..3042620 1 NC_012759.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3042620 dkgA 7952442 dkgA Escherichia coli BW2952 2,5-diketo-D-gluconate reductase A YP_002927922.1 3041793 D 595496 CDS YP_002927923.1 238902127 7952238 3042820..3043746 1 NC_012759.1 MG1655 equivalent: b3013; hypothetical protein 3043746 yqhG 7952238 yqhG Escherichia coli BW2952 hypothetical protein YP_002927923.1 3042820 D 595496 CDS YP_002927924.1 238902128 7953011 3043797..3044054 1 NC_012759.1 MG1655 equivalent: b3014; putative outer membrane lipoprotein 3044054 yqhH 7953011 yqhH Escherichia coli BW2952 putative outer membrane lipoprotein YP_002927924.1 3043797 D 595496 CDS YP_002927925.1 238902129 7955204 complement(3044097..3046316) 1 NC_012759.1 MG1655 equivalent: b4469; hypothetical protein 3046316 ygiQ 7955204 ygiQ Escherichia coli BW2952 hypothetical protein YP_002927925.1 3044097 R 595496 CDS YP_002927926.1 238902130 7952909 complement(3046427..3047839) 1 NC_012759.1 MG1655 equivalent: b3017; repressor protein for FtsI 3047839 ftsP 7952909 ftsP Escherichia coli BW2952 repressor protein for FtsI YP_002927926.1 3046427 R 595496 CDS YP_002927927.1 238902131 7955942 complement(3047914..3048651) 1 NC_012759.1 MG1655 equivalent: b3018; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3048651 plsC 7955942 plsC Escherichia coli BW2952 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002927927.1 3047914 R 595496 CDS YP_002927928.1 238902132 7952226 complement(3048885..3051143) 1 NC_012759.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3051143 parC 7952226 parC Escherichia coli BW2952 DNA topoisomerase IV subunit A YP_002927928.1 3048885 R 595496 CDS YP_002927929.1 238902133 7953335 complement(3051281..3052888) 1 NC_012759.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein 3052888 ygiS 7953335 ygiS Escherichia coli BW2952 putative binding protein YP_002927929.1 3051281 R 595496 CDS YP_002927930.1 238902134 7955736 complement(3053021..3053416) 1 NC_012759.1 MG1655 equivalent: b3021; putative DNA-binding transcriptional regulator 3053416 ygiT 7955736 ygiT Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927930.1 3053021 R 595496 CDS YP_002927931.1 238902135 7954778 complement(3053418..3053714) 1 NC_012759.1 MG1655 equivalent: b3022; putative cyanide hydratase 3053714 mqsR 7954778 mqsR Escherichia coli BW2952 putative cyanide hydratase YP_002927931.1 3053418 R 595496 CDS YP_002927932.1 238902136 7954705 complement(3053919..3054401) 1 NC_012759.1 MG1655 equivalent: b3023; putative transcriptional regulator 3054401 ygiV 7954705 ygiV Escherichia coli BW2952 putative transcriptional regulator YP_002927932.1 3053919 R 595496 CDS YP_002927933.1 238902137 7955629 complement(3054454..3054846) 1 NC_012759.1 MG1655 equivalent: b3024; hypothetical protein 3054846 ygiW 7955629 ygiW Escherichia coli BW2952 hypothetical protein YP_002927933.1 3054454 R 595496 CDS YP_002927934.1 238902138 7952867 3054998..3055657 1 NC_012759.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3055657 qseB 7952867 qseB Escherichia coli BW2952 DNA-binding transcriptional regulator QseB YP_002927934.1 3054998 D 595496 CDS YP_002927935.1 238902139 7953359 3055654..3057003 1 NC_012759.1 MG1655 equivalent: b3026; sensor protein QseC 3057003 qseC 7953359 qseC Escherichia coli BW2952 sensor protein QseC YP_002927935.1 3055654 D 595496 CDS YP_002927936.1 238902140 7956024 complement(3057049..3057381) 1 NC_012759.1 MG1655 equivalent: b3027; hypothetical protein 3057381 ygiZ 7956024 ygiZ Escherichia coli BW2952 hypothetical protein YP_002927936.1 3057049 R 595496 CDS YP_002927937.1 238902141 7952683 3057700..3058281 1 NC_012759.1 MG1655 equivalent: b3028; NADPH quinone reductase 3058281 mdaB 7952683 mdaB Escherichia coli BW2952 NADPH quinone reductase YP_002927937.1 3057700 D 595496 CDS YP_002927938.1 238902142 7954370 3058312..3058626 1 NC_012759.1 MG1655 equivalent: b3029; quinol monooxygenase 3058626 ygiN 7954370 ygiN Escherichia coli BW2952 quinol monooxygenase YP_002927938.1 3058312 D 595496 CDS YP_002927939.1 238902143 7955885 complement(3058674..3060566) 1 NC_012759.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3060566 parE 7955885 parE Escherichia coli BW2952 DNA topoisomerase IV subunit B YP_002927939.1 3058674 R 595496 CDS YP_002927940.1 238902144 7953336 complement(3060595..3061176) 1 NC_012759.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 3061176 yqiA 7953336 yqiA Escherichia coli BW2952 esterase YqiA YP_002927940.1 3060595 R 595496 CDS YP_002927941.1 238902145 7954862 complement(3061176..3062003) 1 NC_012759.1 MG1655 equivalent: b3032; cyclic 3',5'-adenosine monophosphate phosphodiesterase 3062003 cpdA 7954862 cpdA Escherichia coli BW2952 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002927941.1 3061176 R 595496 CDS YP_002927942.1 238902146 7953177 complement(3062028..3062450) 1 NC_012759.1 MG1655 equivalent: b3033; hypothetical protein 3062450 yqiB 7953177 yqiB Escherichia coli BW2952 hypothetical protein YP_002927942.1 3062028 R 595496 CDS YP_002927943.1 238902147 7954712 complement(3062451..3063080) 1 NC_012759.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 3063080 nudF 7954712 nudF Escherichia coli BW2952 ADP-ribose pyrophosphatase NudF YP_002927943.1 3062451 R 595496 CDS YP_002927944.1 238902148 7952433 3063285..3064766 1 NC_012759.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3064766 tolC 7952433 tolC Escherichia coli BW2952 outer membrane channel protein YP_002927944.1 3063285 D 595496 CDS YP_002927945.1 238902149 7956179 3064914..3065585 1 NC_012759.1 MG1655 equivalent: b3037; hypothetical protein 3065585 ygiB 7956179 ygiB Escherichia coli BW2952 hypothetical protein YP_002927945.1 3064914 D 595496 CDS YP_002927946.1 238902150 7952751 3065591..3066751 1 NC_012759.1 MG1655 equivalent: b3038; putative enzyme 3066751 ygiC 7952751 ygiC Escherichia coli BW2952 putative enzyme YP_002927946.1 3065591 D 595496 CDS YP_002927947.1 238902151 7954848 complement(3066789..3067604) 1 NC_012759.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3067604 ygiD 7954848 ygiD Escherichia coli BW2952 hypothetical protein YP_002927947.1 3066789 R 595496 CDS YP_002927948.1 238902152 7954735 3067720..3068493 1 NC_012759.1 MG1655 equivalent: b3040; zinc transporter ZupT 3068493 zupT 7954735 zupT Escherichia coli BW2952 zinc transporter ZupT YP_002927948.1 3067720 D 595496 CDS YP_002927949.1 238902153 7956284 complement(3068983..3069636) 1 NC_012759.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3069636 ribB 7956284 ribB Escherichia coli BW2952 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002927949.1 3068983 R 595496 CDS YP_002927950.1 238902154 7952271 3070010..3070300 1 NC_012759.1 MG1655 equivalent: b3042; hypothetical protein 3070300 yqiC 7952271 yqiC Escherichia coli BW2952 hypothetical protein YP_002927950.1 3070010 D 595496 CDS YP_002927951.1 238902155 7953012 3070584..3071135 1 NC_012759.1 MG1655 equivalent: b3043; putative fimbrial protein 3071135 ygiL 7953012 ygiL Escherichia coli BW2952 putative fimbrial protein YP_002927951.1 3070584 D 595496 CDS YP_002927952.1 238902156 7954899 3071357..3071722 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3071722 insC 7954899 insC Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002927952.1 3071357 D 595496 CDS YP_002927953.1 238902157 7954075 3071680..3072585 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3072585 insD 7954075 insD Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002927953.1 3071680 D 595496 CDS YP_002927954.1 238902158 7954081 3075051..3075800 1 NC_012759.1 MG1655 equivalent: b3047; putative periplasmic pilin chaperone 3075800 yqiH 7954081 yqiH Escherichia coli BW2952 putative periplasmic pilin chaperone YP_002927954.1 3075051 D 595496 CDS YP_002927955.1 238902159 7955303 3075802..3076866 1 NC_012759.1 MG1655 equivalent: b3048; hypothetical protein 3076866 yqiI 7955303 yqiI Escherichia coli BW2952 hypothetical protein YP_002927955.1 3075802 D 595496 CDS YP_002927956.1 238902160 7953013 complement(3076909..3077109) 1 NC_012759.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3077109 glgS 7953013 glgS Escherichia coli BW2952 glycogen synthesis protein GlgS YP_002927956.1 3076909 R 595496 CDS YP_002927957.1 238902161 7954930 3077378..3078007 1 NC_012759.1 MG1655 equivalent: b3050; putative inner membrane protein 3078007 yqiJ 7954930 yqiJ Escherichia coli BW2952 putative inner membrane protein YP_002927957.1 3077378 D 595496 CDS YP_002927958.1 238902162 7955063 3078034..3079695 1 NC_012759.1 MG1655 equivalent: b3051; hypothetical protein 3079695 yqiK 7955063 yqiK Escherichia coli BW2952 hypothetical protein YP_002927958.1 3078034 D 595496 CDS YP_002927959.1 238902163 7952094 complement(3080490..3081923) 1 NC_012759.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3081923 rfaE 7952094 rfaE Escherichia coli BW2952 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002927959.1 3080490 R 595496 CDS YP_002927960.1 238902164 7953686 complement(3081971..3084811) 1 NC_012759.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3084811 glnE 7953686 glnE Escherichia coli BW2952 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002927960.1 3081971 R 595496 CDS YP_002927961.1 238902165 7953671 complement(3084834..3086135) 1 NC_012759.1 MG1655 equivalent: b3054; putative adenylate cyclase 3086135 ygiF 7953671 ygiF Escherichia coli BW2952 putative adenylate cyclase YP_002927961.1 3084834 R 595496 CDS YP_002927962.1 238902166 7954623 3086377..3086997 1 NC_012759.1 MG1655 equivalent: b3055; putative signal transduction protein 3086997 htrG 7954623 htrG Escherichia coli BW2952 putative signal transduction protein YP_002927962.1 3086377 D 595496 CDS YP_002927963.1 238902167 7955593 3087061..3088299 1 NC_012759.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3088299 cca 7955593 cca Escherichia coli BW2952 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002927963.1 3087061 D 595496 CDS YP_002927964.1 238902168 7953750 complement(3088480..3089301) 1 NC_012759.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 3089301 bacA 7953750 bacA Escherichia coli BW2952 UDP pyrophosphate phosphatase YP_002927964.1 3088480 R 595496 CDS YP_002927965.1 238902169 7956249 complement(3089391..3089759) 1 NC_012759.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3089759 folB 7956249 folB Escherichia coli BW2952 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_002927965.1 3089391 R 595496 CDS YP_002927966.1 238902170 7952565 3089864..3090481 1 NC_012759.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 3090481 ygiH 7952565 ygiH Escherichia coli BW2952 putative glycerol-3-phosphate acyltransferase PlsY YP_002927966.1 3089864 D 595496 CDS YP_002927967.1 238902171 7952720 complement(3090494..3091426) 1 NC_012759.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3091426 ttdR 7952720 ttdR Escherichia coli BW2952 transcriptional activator TtdR YP_002927967.1 3090494 R 595496 CDS YP_002927968.1 238902172 7954779 3091633..3092544 1 NC_012759.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3092544 ttdA 7954779 ttdA Escherichia coli BW2952 tartrate dehydratase subunit alpha YP_002927968.1 3091633 D 595496 CDS YP_002927969.1 238902173 7954174 3092541..3093146 1 NC_012759.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3093146 ttdB 7954174 ttdB Escherichia coli BW2952 L(+)-tartrate dehydratase subunit beta YP_002927969.1 3092541 D 595496 CDS YP_002927970.1 238902174 7954175 3093194..3094657 1 NC_012759.1 MG1655 equivalent: b3063; putative tartrate:succinate antiporter 3094657 ttdT 7954175 ttdT Escherichia coli BW2952 putative tartrate:succinate antiporter YP_002927970.1 3093194 D 595496 CDS YP_002927971.1 238902175 7955618 complement(3094700..3095713) 1 NC_012759.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 3095713 ygjD 7955618 ygjD Escherichia coli BW2952 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002927971.1 3094700 R 595496 CDS YP_002927972.1 238902176 7955277 3095951..3096166 1 NC_012759.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3096166 rpsU 7955277 rpsU Escherichia coli BW2952 30S ribosomal protein S21 YP_002927972.1 3095951 D 595496 CDS YP_002927973.1 238902177 7952285 3096277..3098022 1 NC_012759.1 synthesizes RNA primers at the replication forks; DNA primase 3098022 dnaG 7952285 dnaG Escherichia coli BW2952 DNA primase YP_002927973.1 3096277 D 595496 CDS YP_002927974.1 238902178 7953330 3098217..3100058 1 NC_012759.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3100058 rpoD 7953330 rpoD Escherichia coli BW2952 RNA polymerase sigma factor RpoD YP_002927974.1 3098217 D 595496 CDS YP_002927975.1 238902179 7955991 complement(3100137..3100643) 1 NC_012759.1 MG1655 equivalent: b3068; G/U mismatch-specific DNA glycosylase 3100643 mug 7955991 mug Escherichia coli BW2952 G/U mismatch-specific DNA glycosylase YP_002927975.1 3100137 R 595496 CDS YP_002927976.1 238902180 7952146 complement(3100897..3101661) 1 NC_012759.1 MG1655 equivalent: b3070; putative siderophore interacting protein 3101661 yqjH 7952146 yqjH Escherichia coli BW2952 putative siderophore interacting protein YP_002927976.1 3100897 R 595496 CDS YP_002927977.1 238902181 7955591 3101949..3102572 1 NC_012759.1 MG1655 equivalent: b3071; putative transcriptional regulator 3102572 yqjI 7955591 yqjI Escherichia coli BW2952 putative transcriptional regulator YP_002927977.1 3101949 D 595496 CDS YP_002927978.1 238902182 7955636 complement(3102726..3104246) 1 NC_012759.1 MG1655 equivalent: b3072; fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component 3104246 aer 7955636 aer Escherichia coli BW2952 fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component YP_002927978.1 3102726 R 595496 CDS YP_002927979.1 238902183 7953743 3104664..3106043 1 NC_012759.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3106043 ygjG 7953743 ygjG Escherichia coli BW2952 putrescine--2-oxoglutarate aminotransferase YP_002927979.1 3104664 D 595496 CDS YP_002927980.1 238902184 7955833 complement(3106085..3106417) 1 NC_012759.1 MG1655 equivalent: b3074; hypothetical protein 3106417 ygjH 7955833 ygjH Escherichia coli BW2952 hypothetical protein YP_002927980.1 3106085 R 595496 CDS YP_002927981.1 238902185 7952868 3106636..3107619 1 NC_012759.1 MG1655 equivalent: b3075; DNA-binding transcriptional repressor EbgR 3107619 ebgR 7952868 ebgR Escherichia coli BW2952 DNA-binding transcriptional repressor EbgR YP_002927981.1 3106636 D 595496 CDS YP_002927982.1 238902186 7953466 3107803..3110895 1 NC_012759.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3110895 ebgA 7953466 ebgA Escherichia coli BW2952 cryptic beta-D-galactosidase subunit alpha YP_002927982.1 3107803 D 595496 CDS YP_002927983.1 238902187 7953168 3110892..3111341 1 NC_012759.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3111341 ebgC 7953168 ebgC Escherichia coli BW2952 cryptic beta-D-galactosidase subunit beta YP_002927983.1 3110892 D 595496 CDS YP_002927984.1 238902188 7953169 3111404..3112837 1 NC_012759.1 MG1655 equivalent: b3078; putative transporter 3112837 ygjI 7953169 ygjI Escherichia coli BW2952 putative transporter YP_002927984.1 3111404 D 595496 CDS YP_002927985.1 238902189 7955702 3112971..3114041 1 NC_012759.1 MG1655 equivalent: b3079; hypothetical protein 3114041 ygjJ 7955702 ygjJ Escherichia coli BW2952 hypothetical protein YP_002927985.1 3112971 D 595496 CDS YP_002927986.1 238902190 7953015 3114058..3116409 1 NC_012759.1 MG1655 equivalent: b3080; putative glycosyl hydrolase 3116409 ygjK 7953015 ygjK Escherichia coli BW2952 putative glycosyl hydrolase YP_002927986.1 3114058 D 595496 CDS YP_002927987.1 238902191 7954931 3116835..3118853 1 NC_012759.1 MG1655 equivalent: b3081; 2,4-dienoyl-CoA reductase 3118853 fadH 7954931 fadH Escherichia coli BW2952 2,4-dienoyl-CoA reductase YP_002927987.1 3116835 D 595496 CDS YP_002927988.1 238902192 7952237 complement(3118898..3119314) 1 NC_012759.1 MG1655 equivalent: b3082; putative DNA-binding transcriptional regulator 3119314 ygjM 7952237 ygjM Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002927988.1 3118898 R 595496 CDS YP_002927989.1 238902193 7954780 complement(3119311..3119625) 1 NC_012759.1 MG1655 equivalent: b3083; hypothetical protein 3119625 ygjN 7954780 ygjN Escherichia coli BW2952 hypothetical protein YP_002927989.1 3119311 R 595496 CDS YP_002927990.1 238902194 7952869 complement(3119909..3121045) 1 NC_012759.1 MG1655 equivalent: b3084; putative methyltransferase small domain protein 3121045 rlmG 7952869 rlmG Escherichia coli BW2952 putative methyltransferase small domain protein YP_002927990.1 3119909 R 595496 CDS YP_002927991.1 238902195 7955162 3121130..3121633 1 NC_012759.1 MG1655 equivalent: b3085; putative metal dependent hydrolase 3121633 ygjP 7955162 ygjP Escherichia coli BW2952 putative metal dependent hydrolase YP_002927991.1 3121130 D 595496 CDS YP_002927992.1 238902196 7955145 3121710..3122402 1 NC_012759.1 MG1655 equivalent: b3086; putative thioredoxin-like protein 3122402 ygjQ 7955145 ygjQ Escherichia coli BW2952 putative thioredoxin-like protein YP_002927992.1 3121710 D 595496 CDS YP_002927993.1 238902197 7955622 3122481..3123467 1 NC_012759.1 MG1655 equivalent: b3087; putative NAD(P)-binding dehydrogenase 3123467 ygjR 7955622 ygjR Escherichia coli BW2952 putative NAD(P)-binding dehydrogenase YP_002927993.1 3122481 D 595496 CDS YP_002927994.1 238902198 7952193 3123750..3124715 1 NC_012759.1 MG1655 equivalent: b3088; putative inner membrane protein, part of terminus 3124715 alx 7952193 alx Escherichia coli BW2952 putative inner membrane protein, part of terminus YP_002927994.1 3123750 D 595496 CDS YP_002927995.1 238902199 7955078 3125114..3126358 1 NC_012759.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3126358 sstT 7955078 sstT Escherichia coli BW2952 serine/threonine transporter SstT YP_002927995.1 3125114 D 595496 CDS YP_002927996.1 238902200 7956056 complement(3126363..3126914) 1 NC_012759.1 MG1655 equivalent: b3090; hypothetical protein 3126914 ygjV 7956056 ygjV Escherichia coli BW2952 hypothetical protein YP_002927996.1 3126363 R 595496 CDS YP_002927997.1 238902201 7952684 complement(3126997..3128484) 1 NC_012759.1 MG1655 equivalent: b3091; altronate hydrolase 3128484 uxaA 7952684 uxaA Escherichia coli BW2952 altronate hydrolase YP_002927997.1 3126997 R 595496 CDS YP_002927998.1 238902202 7952461 complement(3128499..3129911) 1 NC_012759.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3129911 uxaC 7952461 uxaC Escherichia coli BW2952 glucuronate isomerase YP_002927998.1 3128499 R 595496 CDS YP_002927999.1 238902203 7956266 3130274..3131692 1 NC_012759.1 MG1655 equivalent: b3093; hexuronate transporter 3131692 exuT 7956266 exuT Escherichia coli BW2952 hexuronate transporter YP_002927999.1 3130274 D 595496 CDS YP_002928000.1 238902204 7953906 3131822..3132598 1 NC_012759.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3132598 exuR 7953906 exuR Escherichia coli BW2952 DNA-binding transcriptional repressor ExuR YP_002928000.1 3131822 D 595496 CDS YP_002928001.1 238902205 7953467 3132943..3133605 1 NC_012759.1 MG1655 equivalent: b3095; hypothetical protein 3133605 yqjA 7953467 yqjA Escherichia coli BW2952 hypothetical protein YP_002928001.1 3132943 D 595496 CDS YP_002928002.1 238902206 7952721 3133609..3133992 1 NC_012759.1 MG1655 equivalent: b3096; hypothetical protein 3133992 yqjB 7952721 yqjB Escherichia coli BW2952 hypothetical protein YP_002928002.1 3133609 D 595496 CDS YP_002928003.1 238902207 7953016 3134139..3134507 1 NC_012759.1 MG1655 equivalent: b3097; hypothetical protein 3134507 yqjC 7953016 yqjC Escherichia coli BW2952 hypothetical protein YP_002928003.1 3134139 D 595496 CDS YP_002928004.1 238902208 7953017 3134545..3134850 1 NC_012759.1 MG1655 equivalent: b3098; hypothetical protein 3134850 yqjD 7953017 yqjD Escherichia coli BW2952 hypothetical protein YP_002928004.1 3134545 D 595496 CDS YP_002928005.1 238902209 7953018 3134853..3135257 1 NC_012759.1 MG1655 equivalent: b3099; hypothetical protein 3135257 yqjE 7953018 yqjE Escherichia coli BW2952 hypothetical protein YP_002928005.1 3134853 D 595496 CDS YP_002928006.1 238902210 7952722 3135247..3135546 1 NC_012759.1 MG1655 equivalent: b3100; hypothetical protein 3135546 yqjK 7952722 yqjK Escherichia coli BW2952 hypothetical protein YP_002928006.1 3135247 D 595496 CDS YP_002928007.1 238902211 7953019 3135732..3136124 1 NC_012759.1 MG1655 equivalent: b3101; putative quinol oxidase subunit 3136124 yqjF 7953019 yqjF Escherichia coli BW2952 putative quinol oxidase subunit YP_002928007.1 3135732 D 595496 CDS YP_002928008.1 238902212 7955554 3136194..3137180 1 NC_012759.1 MG1655 equivalent: b3102; putative S-transferase 3137180 yqjG 7955554 yqjG Escherichia coli BW2952 putative S-transferase YP_002928008.1 3136194 D 595496 CDS YP_002928009.1 238902213 7955599 3137474..3137839 1 NC_012759.1 MG1655 equivalent: b3103; putative inner membrane protein 3137839 yhaH 7955599 yhaH Escherichia coli BW2952 putative inner membrane protein YP_002928009.1 3137474 D 595496 CDS YP_002928010.1 238902214 7955064 3138081..3138437 1 NC_012759.1 MG1655 equivalent: b3104; putative inner membrane protein 3138437 yhaI 7955064 yhaI Escherichia coli BW2952 putative inner membrane protein YP_002928010.1 3138081 D 595496 CDS YP_002928011.1 238902215 7955065 complement(3138488..3139384) 1 NC_012759.1 MG1655 equivalent: b3105; putative DNA-binding transcriptional regulator 3139384 yhaJ 7955065 yhaJ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928011.1 3138488 R 595496 CDS YP_002928012.1 238902216 7954781 3139489..3140190 1 NC_012759.1 MG1655 equivalent: b3106; putative pirin-related protein 3140190 yhaK 7954781 yhaK Escherichia coli BW2952 putative pirin-related protein YP_002928012.1 3139489 D 595496 CDS YP_002928013.1 238902217 7955323 3140213..3140377 1 NC_012759.1 MG1655 equivalent: b3107; hypothetical protein 3140377 yhaL 7955323 yhaL Escherichia coli BW2952 hypothetical protein YP_002928013.1 3140213 D 595496 CDS YP_002928014.1 238902218 7955511 complement(3140511..3141821) 1 NC_012759.1 MG1655 equivalent: b4470; hypothetical protein 3141821 yhaM 7955511 yhaM Escherichia coli BW2952 hypothetical protein YP_002928014.1 3140511 R 595496 CDS YP_002928015.1 238902219 7952910 complement(3141849..3143180) 1 NC_012759.1 MG1655 equivalent: b3110; putative transporter 3143180 yhaO 7952910 yhaO Escherichia coli BW2952 putative transporter YP_002928015.1 3141849 R 595496 CDS YP_002928016.1 238902220 7955665 complement(3143455..3144819) 1 NC_012759.1 MG1655 equivalent: b4471; L-serine dehydratase 3 3144819 tdcG 7955665 tdcG Escherichia coli BW2952 L-serine dehydratase 3 YP_002928016.1 3143455 R 595496 CDS YP_002928017.1 238902221 7954172 complement(3144891..3145280) 1 NC_012759.1 MG1655 equivalent: b3113; hypothetical protein 3145280 tdcF 7954172 tdcF Escherichia coli BW2952 hypothetical protein YP_002928017.1 3144891 R 595496 CDS YP_002928018.1 238902222 7955124 complement(3145294..3147588) 1 NC_012759.1 MG1655 equivalent: b3114; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase 3147588 tdcE 7955124 tdcE Escherichia coli BW2952 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase YP_002928018.1 3145294 R 595496 CDS YP_002928019.1 238902223 7955851 complement(3147622..3148830) 1 NC_012759.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3148830 tdcD 7955851 tdcD Escherichia coli BW2952 propionate/acetate kinase YP_002928019.1 3147622 R 595496 CDS YP_002928020.1 238902224 7955773 complement(3148856..3150187) 1 NC_012759.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3150187 tdcC 7955773 tdcC Escherichia coli BW2952 threonine/serine transporter TdcC YP_002928020.1 3148856 R 595496 CDS YP_002928021.1 238902225 7954176 complement(3150209..3151198) 1 NC_012759.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3151198 tdcB 7954176 tdcB Escherichia coli BW2952 threonine dehydratase YP_002928021.1 3150209 R 595496 CDS YP_002928022.1 238902226 7952610 complement(3151297..3152235) 1 NC_012759.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3152235 tdcA 7952610 tdcA Escherichia coli BW2952 DNA-binding transcriptional activator TdcA YP_002928022.1 3151297 R 595496 CDS YP_002928023.1 238902227 7953370 3152550..3152768 1 NC_012759.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3152768 tdcR 7953370 tdcR Escherichia coli BW2952 DNA-binding transcriptional activator TdcR YP_002928023.1 3152550 D 595496 CDS YP_002928024.1 238902228 7953382 3153024..3153563 1 NC_012759.1 MG1655 equivalent: b3120; hypothetical protein 3153563 yhaB 7953382 yhaB Escherichia coli BW2952 hypothetical protein YP_002928024.1 3153024 D 595496 CDS YP_002928025.1 238902229 7955512 3153585..3154772 1 NC_012759.1 MG1655 equivalent: b3121; hypothetical protein 3154772 yhaC 7955512 yhaC Escherichia coli BW2952 hypothetical protein YP_002928025.1 3153585 D 595496 CDS YP_002928026.1 238902230 7952095 complement(3155795..3156940) 1 NC_012759.1 MG1655 equivalent: b3124; glycerate kinase 3156940 garK 7952095 garK Escherichia coli BW2952 glycerate kinase YP_002928026.1 3155795 R 595496 CDS YP_002928027.1 238902231 7953843 complement(3157037..3157921) 1 NC_012759.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3157921 garR 7953843 garR Escherichia coli BW2952 tartronate semialdehyde reductase YP_002928027.1 3157037 R 595496 CDS YP_002928028.1 238902232 7956107 complement(3157957..3158727) 1 NC_012759.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3158727 garL 7956107 garL Escherichia coli BW2952 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_002928028.1 3157957 R 595496 CDS YP_002928029.1 238902233 7952456 complement(3158743..3160077) 1 NC_012759.1 MG1655 equivalent: b3127; putative (D)-galactarate transporter 3160077 garP 7952456 garP Escherichia coli BW2952 putative (D)-galactarate transporter YP_002928029.1 3158743 R 595496 CDS YP_002928030.1 238902234 7954582 3160452..3162023 1 NC_012759.1 MG1655 equivalent: b3128; (D)-galactarate dehydrogenase 3162023 garD 7954582 garD Escherichia coli BW2952 (D)-galactarate dehydrogenase YP_002928030.1 3160452 D 595496 CDS YP_002928031.1 238902235 7952216 3162172..3162507 1 NC_012759.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 3162507 sohA 7952216 sohA Escherichia coli BW2952 putative regulator PrlF YP_002928031.1 3162172 D 595496 CDS YP_002928032.1 238902236 7955561 3162507..3162971 1 NC_012759.1 MG1655 equivalent: b3130; hypothetical protein 3162971 yhaV 7955561 yhaV Escherichia coli BW2952 hypothetical protein YP_002928032.1 3162507 D 595496 CDS YP_002928033.1 238902237 7953020 complement(3163026..3163835) 1 NC_012759.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3163835 agaR 7953020 agaR Escherichia coli BW2952 DNA-binding transcriptional regulator AgaR YP_002928033.1 3163026 R 595496 CDS YP_002928034.1 238902238 7953409 3164084..3165364 1 NC_012759.1 MG1655 equivalent: b3132; tagatose 6-phosphate aldolase 1, kbaZ subunit 3165364 kbaZ 7953409 kbaZ Escherichia coli BW2952 tagatose 6-phosphate aldolase 1, kbaZ subunit YP_002928034.1 3164084 D 595496 CDS YP_002928035.1 238902239 7956103 3165387..3165860 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3165860 agaV 7956103 agaV Escherichia coli BW2952 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002928035.1 3165387 D 595496 CDS YP_002928036.1 238902240 7954336 3167146..3168300 1 NC_012759.1 MG1655 equivalent: b3136; tagatose-6-phosphate ketose/aldose isomerase 3168300 agaS 7954336 agaS Escherichia coli BW2952 tagatose-6-phosphate ketose/aldose isomerase YP_002928036.1 3167146 D 595496 CDS YP_002928037.1 238902241 7956104 3168313..3169173 1 NC_012759.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3169173 kbaY 7956104 kbaY Escherichia coli BW2952 tagatose-bisphosphate aldolase YP_002928037.1 3168313 D 595496 CDS YP_002928038.1 238902242 7956102 3169340..3169816 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3169816 agaB 7956102 agaB Escherichia coli BW2952 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002928038.1 3169340 D 595496 CDS YP_002928039.1 238902243 7954337 3169855..3170658 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3170658 agaC 7954337 agaC Escherichia coli BW2952 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_002928039.1 3169855 D 595496 CDS YP_002928040.1 238902244 7954338 3170648..3171439 1 NC_012759.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3171439 agaD 7954338 agaD Escherichia coli BW2952 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_002928040.1 3170648 D 595496 CDS YP_002928041.1 238902245 7954339 3171440..3172195 1 NC_012759.1 MG1655 equivalent: b3141; galactosamine-6-phosphate isomerase 3172195 agaI 7954339 agaI Escherichia coli BW2952 galactosamine-6-phosphate isomerase YP_002928041.1 3171440 D 595496 CDS YP_002928042.1 238902246 7953760 3172596..3173180 1 NC_012759.1 MG1655 equivalent: b3142; putative fimbrial-like adhesin protein 3173180 yraH 7953760 yraH Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002928042.1 3172596 D 595496 CDS YP_002928043.1 238902247 7954900 3173260..3173955 1 NC_012759.1 MG1655 equivalent: b3143; putative periplasmic pilin chaperone 3173955 yraI 7954900 yraI Escherichia coli BW2952 putative periplasmic pilin chaperone YP_002928043.1 3173260 D 595496 CDS YP_002928044.1 238902248 7955304 3173984..3176500 1 NC_012759.1 MG1655 equivalent: b3144; putative outer membrane protein 3176500 yraJ 7955304 yraJ Escherichia coli BW2952 putative outer membrane protein YP_002928044.1 3173984 D 595496 CDS YP_002928045.1 238902249 7955213 3176511..3177602 1 NC_012759.1 MG1655 equivalent: b3145; putative fimbrial-like adhesin protein 3177602 yraK 7955213 yraK Escherichia coli BW2952 putative fimbrial-like adhesin protein YP_002928045.1 3176511 D 595496 CDS YP_002928046.1 238902250 7954901 complement(3177645..3178505) 1 NC_012759.1 MG1655 equivalent: b3146; putative methyltransferase 3178505 yraL 7954901 yraL Escherichia coli BW2952 putative methyltransferase YP_002928046.1 3177645 R 595496 CDS YP_002928047.1 238902251 7955156 3178570..3180606 1 NC_012759.1 MG1655 equivalent: b3147; hypothetical protein 3180606 yraM 7955156 yraM Escherichia coli BW2952 hypothetical protein YP_002928047.1 3178570 D 595496 CDS YP_002928048.1 238902252 7953021 3180564..3180959 1 NC_012759.1 MG1655 equivalent: b3148; hypothetical protein 3180959 yraN 7953021 yraN Escherichia coli BW2952 hypothetical protein YP_002928048.1 3180564 D 595496 CDS YP_002928049.1 238902253 7953022 3180979..3181569 1 NC_012759.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3181569 diaA 7953022 diaA Escherichia coli BW2952 DnaA initiator-associating protein DiaA YP_002928049.1 3180979 D 595496 CDS YP_002928050.1 238902254 7953337 3181579..3182154 1 NC_012759.1 MG1655 equivalent: b3150; hypothetical protein 3182154 yraP 7953337 yraP Escherichia coli BW2952 hypothetical protein YP_002928050.1 3181579 D 595496 CDS YP_002928051.1 238902255 7955514 complement(3182268..3183308) 1 NC_012759.1 MG1655 equivalent: b3151; putative permease 3183308 yraQ 7955514 yraQ Escherichia coli BW2952 putative permease YP_002928051.1 3182268 R 595496 CDS YP_002928052.1 238902256 7955307 complement(3183381..3184016) 1 NC_012759.1 MG1655 equivalent: b3152; putative nucleoside-diphosphate-sugar epimerase 3184016 yraR 7955307 yraR Escherichia coli BW2952 putative nucleoside-diphosphate-sugar epimerase YP_002928052.1 3183381 R 595496 CDS YP_002928053.1 238902257 7955186 3184144..3184662 1 NC_012759.1 MG1655 equivalent: b3153; putative intracellular protease 3184662 yhbO 7955186 yhbO Escherichia coli BW2952 putative intracellular protease YP_002928053.1 3184144 D 595496 CDS YP_002928054.1 238902258 7955080 complement(3184642..3185085) 1 NC_012759.1 MG1655 equivalent: b3154; hypothetical protein 3185085 yhbP 7955080 yhbP Escherichia coli BW2952 hypothetical protein YP_002928054.1 3184642 R 595496 CDS YP_002928055.1 238902259 7952870 3185136..3185438 1 NC_012759.1 MG1655 equivalent: b3155; GIY-YIG nuclease superfamily protein 3185438 yhbQ 7952870 yhbQ Escherichia coli BW2952 GIY-YIG nuclease superfamily protein YP_002928055.1 3185136 D 595496 CDS YP_002928056.1 238902260 7954835 complement(3185425..3185928) 1 NC_012759.1 MG1655 equivalent: b3156; putative acyltransferase with acyl-CoA N-acyltransferase domain 3185928 yhbS 7954835 yhbS Escherichia coli BW2952 putative acyltransferase with acyl-CoA N-acyltransferase domain YP_002928056.1 3185425 R 595496 CDS YP_002928057.1 238902261 7954618 complement(3185922..3186446) 1 NC_012759.1 MG1655 equivalent: b3157; putative lipid carrier protein 3186446 yhbT 7954618 yhbT Escherichia coli BW2952 putative lipid carrier protein YP_002928057.1 3185922 R 595496 CDS YP_002928058.1 238902262 7955101 3186655..3187650 1 NC_012759.1 MG1655 equivalent: b3158; putative peptidase (collagenase-like) 3187650 yhbU 7955101 yhbU Escherichia coli BW2952 putative peptidase (collagenase-like) YP_002928058.1 3186655 D 595496 CDS YP_002928059.1 238902263 7955287 3187659..3188537 1 NC_012759.1 MG1655 equivalent: b3159; putative protease 3188537 yhbV 7955287 yhbV Escherichia coli BW2952 putative protease YP_002928059.1 3187659 D 595496 CDS YP_002928060.1 238902264 7955331 3188618..3189625 1 NC_012759.1 MG1655 equivalent: b3160; hypothetical protein 3189625 yhbW 7955331 yhbW Escherichia coli BW2952 hypothetical protein YP_002928060.1 3188618 D 595496 CDS YP_002928061.1 238902265 7954849 complement(3189743..3190987) 1 NC_012759.1 tryptophan transporter of high affinity; tryptophan permease 3190987 mtr 7954849 mtr Escherichia coli BW2952 tryptophan permease YP_002928061.1 3189743 R 595496 CDS YP_002928062.1 238902266 7956213 complement(3191141..3193030) 1 NC_012759.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3193030 deaD 7956213 deaD Escherichia coli BW2952 ATP-dependent RNA helicase DeaD YP_002928062.1 3191141 R 595496 CDS YP_002928063.1 238902267 7952534 complement(3193210..3194094) 1 NC_012759.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3194094 nlpI 7952534 nlpI Escherichia coli BW2952 lipoprotein NlpI YP_002928063.1 3193210 R 595496 CDS YP_002928064.1 238902268 7952871 complement(3194203..3196338) 1 NC_012759.1 MG1655 equivalent: b3164; polynucleotide phosphorylase/polyadenylase 3196338 pnp 7952871 pnp Escherichia coli BW2952 polynucleotide phosphorylase/polyadenylase YP_002928064.1 3194203 R 595496 CDS YP_002928065.1 238902269 7952194 complement(3196585..3196854) 1 NC_012759.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3196854 rpsO 7952194 rpsO Escherichia coli BW2952 30S ribosomal protein S15 YP_002928065.1 3196585 R 595496 CDS YP_002928066.1 238902270 7952278 complement(3197003..3197947) 1 NC_012759.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3197947 truB 7952278 truB Escherichia coli BW2952 tRNA pseudouridine synthase B YP_002928066.1 3197003 R 595496 CDS YP_002928067.1 238902271 7956202 complement(3197947..3198348) 1 NC_012759.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3198348 rbfA 7956202 rbfA Escherichia coli BW2952 ribosome-binding factor A YP_002928067.1 3197947 R 595496 CDS YP_002928068.1 238902272 7952294 complement(3198512..3201184) 1 NC_012759.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3201184 infB 7952294 infB Escherichia coli BW2952 translation initiation factor IF-2 YP_002928068.1 3198512 R 595496 CDS YP_002928069.1 238902273 7953736 complement(3201209..3202696) 1 NC_012759.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3202696 nusA 7953736 nusA Escherichia coli BW2952 transcription elongation factor NusA YP_002928069.1 3201209 R 595496 CDS YP_002928070.1 238902274 7956171 complement(3202724..3203182) 1 NC_012759.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3203182 yhbC 7956171 yhbC Escherichia coli BW2952 hypothetical protein YP_002928070.1 3202724 R 595496 CDS YP_002928071.1 238902275 7952068 3203807..3205150 1 NC_012759.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3205150 argG 7952068 argG Escherichia coli BW2952 argininosuccinate synthase YP_002928071.1 3203807 D 595496 CDS YP_002928072.1 238902276 7952502 complement(3205158..3206783) 1 NC_012759.1 MG1655 equivalent: b3173; putative hydrolase, inner membrane 3206783 yhbX 7952502 yhbX Escherichia coli BW2952 putative hydrolase, inner membrane YP_002928072.1 3205158 R 595496 CDS YP_002928073.1 238902277 7952069 complement(3207343..3207675) 1 NC_012759.1 MG1655 equivalent: b3175; preprotein translocase subunit SecG 3207675 secG 7952069 secG Escherichia coli BW2952 preprotein translocase subunit SecG YP_002928073.1 3207343 R 595496 CDS YP_002928074.1 238902278 7955760 complement(3207903..3209240) 1 NC_012759.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3209240 glmM 7955760 glmM Escherichia coli BW2952 phosphoglucosamine mutase YP_002928074.1 3207903 R 595496 CDS YP_002928075.1 238902279 7954532 complement(3209233..3210081) 1 NC_012759.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3210081 folP 7954532 folP Escherichia coli BW2952 dihydropteroate synthase YP_002928075.1 3209233 R 595496 CDS YP_002928076.1 238902280 7952383 complement(3210171..3212105) 1 NC_012759.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3212105 hflB 7952383 hflB Escherichia coli BW2952 ATP-dependent metalloprotease YP_002928076.1 3210171 R 595496 CDS YP_002928077.1 238902281 7955780 complement(3212205..3212834) 1 NC_012759.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 3212834 rrmJ 7955780 rrmJ Escherichia coli BW2952 23S rRNA methyltransferase J YP_002928077.1 3212205 R 595496 CDS YP_002928078.1 238902282 7952245 3212960..3213253 1 NC_012759.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3213253 yhbY 7952245 yhbY Escherichia coli BW2952 RNA-binding protein YhbY YP_002928078.1 3212960 D 595496 CDS YP_002928079.1 238902283 7955573 complement(3213409..3213885) 1 NC_012759.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3213885 greA 7955573 greA Escherichia coli BW2952 transcription elongation factor GreA YP_002928079.1 3213409 R 595496 CDS YP_002928080.1 238902284 7956167 3214133..3215566 1 NC_012759.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3215566 dacB 7956167 dacB Escherichia coli BW2952 D-alanyl-D-alanine carboxypeptidase YP_002928080.1 3214133 D 595496 CDS YP_002928081.1 238902285 7953217 complement(3215752..3216924) 1 NC_012759.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3216924 obgE 7953217 obgE Escherichia coli BW2952 GTPase ObgE YP_002928081.1 3215752 R 595496 CDS YP_002928082.1 238902286 7953879 complement(3216940..3217905) 1 NC_012759.1 MG1655 equivalent: b3184; hypothetical protein 3217905 yhbE 7953879 yhbE Escherichia coli BW2952 hypothetical protein YP_002928082.1 3216940 R 595496 CDS YP_002928083.1 238902287 7952685 complement(3218032..3218289) 1 NC_012759.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3218289 rpmA 7952685 rpmA Escherichia coli BW2952 50S ribosomal protein L27 YP_002928083.1 3218032 R 595496 CDS YP_002928084.1 238902288 7952354 complement(3218310..3218621) 1 NC_012759.1 MG1655 equivalent: b3186; 50S ribosomal protein L21 3218621 rplU 7952354 rplU Escherichia coli BW2952 50S ribosomal protein L21 YP_002928084.1 3218310 R 595496 CDS YP_002928085.1 238902289 7952349 3218880..3219851 1 NC_012759.1 MG1655 equivalent: b3187; octaprenyl diphosphate synthase 3219851 ispB 7952349 ispB Escherichia coli BW2952 octaprenyl diphosphate synthase YP_002928085.1 3218880 D 595496 CDS YP_002928086.1 238902290 7954420 3220079..3220357 1 NC_012759.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3220357 sfsB 7954420 sfsB Escherichia coli BW2952 DNA-binding transcriptional regulator Nlp YP_002928086.1 3220079 D 595496 CDS YP_002928087.1 238902291 7953391 complement(3220405..3221664) 1 NC_012759.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3221664 murA 7953391 murA Escherichia coli BW2952 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002928087.1 3220405 R 595496 CDS YP_002928088.1 238902292 7956239 complement(3221719..3221973) 1 NC_012759.1 MG1655 equivalent: b3190; putative DNA-binding transcriptional regulator 3221973 yrbA 7956239 yrbA Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928088.1 3221719 R 595496 CDS YP_002928089.1 238902293 7954782 complement(3222133..3222426) 1 NC_012759.1 MG1655 equivalent: b3191; hypothetical protein 3222426 yrbB 7954782 yrbB Escherichia coli BW2952 hypothetical protein YP_002928089.1 3222133 R 595496 CDS YP_002928090.1 238902294 7955416 complement(3222426..3223061) 1 NC_012759.1 MG1655 equivalent: b3192; putative ABC-type organic solvent transporter 3223061 yrbC 7955416 yrbC Escherichia coli BW2952 putative ABC-type organic solvent transporter YP_002928090.1 3222426 R 595496 CDS YP_002928091.1 238902295 7954599 complement(3223080..3223631) 1 NC_012759.1 MG1655 equivalent: b3193; putative ABC-type organic solvent transporter 3223631 yrbD 7954599 yrbD Escherichia coli BW2952 putative ABC-type organic solvent transporter YP_002928091.1 3223080 R 595496 CDS YP_002928092.1 238902296 7954600 complement(3223636..3224418) 1 NC_012759.1 MG1655 equivalent: b3194; putative toluene transporter subunit: membrane component of ABC superfamily 3224418 yrbE 7954600 yrbE Escherichia coli BW2952 putative toluene transporter subunit: membrane component of ABC superfamily YP_002928092.1 3223636 R 595496 CDS YP_002928093.1 238902297 7955625 complement(3224426..3225235) 1 NC_012759.1 ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF 3225235 yrbF 7955625 yrbF Escherichia coli BW2952 putative ABC transporter ATP-binding protein YrbF YP_002928093.1 3224426 R 595496 CDS YP_002928094.1 238902298 7955624 3225445..3226422 1 NC_012759.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3226422 yrbG 7955624 yrbG Escherichia coli BW2952 putative calcium/sodium:proton antiporter YP_002928094.1 3225445 D 595496 CDS YP_002928095.1 238902299 7954673 3226436..3227422 1 NC_012759.1 MG1655 equivalent: b3197; D-arabinose 5-phosphate isomerase 3227422 kdsD 7954673 kdsD Escherichia coli BW2952 D-arabinose 5-phosphate isomerase YP_002928095.1 3226436 D 595496 CDS YP_002928096.1 238902300 7953227 3227443..3228009 1 NC_012759.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3228009 kdsC 7953227 kdsC Escherichia coli BW2952 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002928096.1 3227443 D 595496 CDS YP_002928097.1 238902301 7952300 3228006..3228581 1 NC_012759.1 MG1655 equivalent: b3199; hypothetical protein 3228581 yrbK 7952300 yrbK Escherichia coli BW2952 hypothetical protein YP_002928097.1 3228006 D 595496 CDS YP_002928098.1 238902302 7953023 3228550..3229107 1 NC_012759.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3229107 lptA 7953023 lptA Escherichia coli BW2952 lipopolysaccharide transport periplasmic protein LptA YP_002928098.1 3228550 D 595496 CDS YP_002928099.1 238902303 7955737 3229114..3229839 1 NC_012759.1 MG1655 equivalent: b3201; putative ABC transporter ATP-binding protein YhbG 3229839 lptB 7955737 lptB Escherichia coli BW2952 putative ABC transporter ATP-binding protein YhbG YP_002928099.1 3229114 D 595496 CDS YP_002928100.1 238902304 7955725 3229887..3231320 1 NC_012759.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3231320 rpoN 7955725 rpoN Escherichia coli BW2952 RNA polymerase factor sigma-54 YP_002928100.1 3229887 D 595496 CDS YP_002928101.1 238902305 7955990 3231343..3231630 1 NC_012759.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3231630 hpf 7955990 hpf Escherichia coli BW2952 putative sigma(54) modulation protein YP_002928101.1 3231343 D 595496 CDS YP_002928102.1 238902306 7955571 3231748..3232239 1 NC_012759.1 MG1655 equivalent: b3204; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3232239 ptsN 7955571 ptsN Escherichia coli BW2952 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_002928102.1 3231748 D 595496 CDS YP_002928103.1 238902307 7956087 3232285..3233139 1 NC_012759.1 MG1655 equivalent: b3205; hypothetical protein 3233139 yhbJ 7956087 yhbJ Escherichia coli BW2952 hypothetical protein YP_002928103.1 3232285 D 595496 CDS YP_002928104.1 238902308 7955546 3233136..3233408 1 NC_012759.1 MG1655 equivalent: b3206; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3233408 npr 7955546 npr Escherichia coli BW2952 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_002928104.1 3233136 D 595496 CDS YP_002928105.1 238902309 7954540 3233622..3234254 1 NC_012759.1 MG1655 equivalent: b3207; hypothetical protein 3234254 yrbL 7954540 yrbL Escherichia coli BW2952 hypothetical protein YP_002928105.1 3233622 D 595496 CDS YP_002928106.1 238902310 7955515 complement(3234251..3234979) 1 NC_012759.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3234979 mtgA 7955515 mtgA Escherichia coli BW2952 monofunctional biosynthetic peptidoglycan transglycosylase YP_002928106.1 3234251 R 595496 CDS YP_002928107.1 238902311 7952580 complement(3234976..3235629) 1 NC_012759.1 MG1655 equivalent: b3209; isoprenoid biosynthesis protein with amidotransferase-like domain 3235629 elbB 7952580 elbB Escherichia coli BW2952 isoprenoid biosynthesis protein with amidotransferase-like domain YP_002928107.1 3234976 R 595496 CDS YP_002928108.1 238902312 7952195 complement(3235859..3238195) 1 NC_012759.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3238195 arcB 7952195 arcB Escherichia coli BW2952 aerobic respiration control sensor protein ArcB YP_002928108.1 3235859 R 595496 CDS YP_002928109.1 238902313 7953928 complement(3238291..3239220) 1 NC_012759.1 MG1655 equivalent: b3211; putative Fe-S oxidoreductase 3239220 yhcC 7953928 yhcC Escherichia coli BW2952 putative Fe-S oxidoreductase YP_002928109.1 3238291 R 595496 CDS YP_002928110.1 238902314 7954873 3239802..3244355 1 NC_012759.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3244355 gltB 7954873 gltB Escherichia coli BW2952 glutamate synthase subunit alpha YP_002928110.1 3239802 D 595496 CDS YP_002928111.1 238902315 7953823 3244368..3245786 1 NC_012759.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3245786 gltD 7953823 gltD Escherichia coli BW2952 glutamate synthase subunit beta YP_002928111.1 3244368 D 595496 CDS YP_002928112.1 238902316 7953822 3246346..3247110 1 NC_012759.1 MG1655 equivalent: b3214; hypothetical protein 3247110 gltF 7953822 gltF Escherichia coli BW2952 hypothetical protein YP_002928112.1 3246346 D 595496 CDS YP_002928113.1 238902317 7954495 3247282..3247956 1 NC_012759.1 member of the periplasmic pilus chaperone family of proteins; putative periplasmic chaperone protein 3247956 yhcA 7954495 yhcA Escherichia coli BW2952 putative periplasmic chaperone protein YP_002928113.1 3247282 D 595496 CDS YP_002928114.1 238902318 7955298 3247977..3250358 1 NC_012759.1 MG1655 equivalent: b3216; putative outer membrane protein 3250358 yhcD 7955298 yhcD Escherichia coli BW2952 putative outer membrane protein YP_002928114.1 3247977 D 595496 CDS YP_002928115.1 238902319 7955214 complement(3250872..3251888) 1 NC_012759.1 MG1655 equivalent: b3218; IS5 transposase and trans-activator 3251888 insH 7955214 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002928115.1 3250872 R 595496 CDS YP_002928116.1 238902320 7954043 3252096..3252812 1 NC_012759.1 MG1655 equivalent: b3219; putative transcriptional regulator 3252812 yhcF 7954043 yhcF Escherichia coli BW2952 putative transcriptional regulator YP_002928116.1 3252096 D 595496 CDS YP_002928117.1 238902321 7955637 3252997..3254124 1 NC_012759.1 MG1655 equivalent: b3220; hypothetical protein 3254124 yhcG 7955637 yhcG Escherichia coli BW2952 hypothetical protein YP_002928117.1 3252997 D 595496 CDS YP_002928118.1 238902322 7953024 complement(3254184..3254648) 1 NC_012759.1 MG1655 equivalent: b3221; hypothetical protein 3254648 yhcH 7953024 yhcH Escherichia coli BW2952 hypothetical protein YP_002928118.1 3254184 R 595496 CDS YP_002928119.1 238902323 7952873 complement(3254645..3255520) 1 NC_012759.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3255520 nanK 7952873 nanK Escherichia coli BW2952 N-acetylmannosamine kinase YP_002928119.1 3254645 R 595496 CDS YP_002928120.1 238902324 7955177 complement(3255517..3256206) 1 NC_012759.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3256206 nanE 7955177 nanE Escherichia coli BW2952 N-acetylmannosamine-6-phosphate 2-epimerase YP_002928120.1 3255517 R 595496 CDS YP_002928121.1 238902325 7955178 complement(3256254..3257744) 1 NC_012759.1 MG1655 equivalent: b3224; putative sialic acid transporter 3257744 nanT 7955178 nanT Escherichia coli BW2952 putative sialic acid transporter YP_002928121.1 3256254 R 595496 CDS YP_002928122.1 238902326 7956042 complement(3257853..3258746) 1 NC_012759.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3258746 nanA 7956042 nanA Escherichia coli BW2952 N-acetylneuraminate lyase YP_002928122.1 3257853 R 595496 CDS YP_002928123.1 238902327 7954346 complement(3258868..3259659) 1 NC_012759.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3259659 nanR 7954346 nanR Escherichia coli BW2952 transcriptional regulator NanR YP_002928123.1 3258868 R 595496 CDS YP_002928124.1 238902328 7953410 3260039..3261406 1 NC_012759.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 3261406 dcuD 7953410 dcuD Escherichia coli BW2952 putative cryptic C4-dicarboxylate transporter DcuD YP_002928124.1 3260039 D 595496 CDS YP_002928125.1 238902329 7955703 complement(3261449..3261946) 1 NC_012759.1 MG1655 equivalent: b3228; ClpXP protease specificity-enhancing factor 3261946 sspB 7955703 sspB Escherichia coli BW2952 ClpXP protease specificity-enhancing factor YP_002928125.1 3261449 R 595496 CDS YP_002928126.1 238902330 7952645 complement(3261952..3262590) 1 NC_012759.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3262590 sspA 7952645 sspA Escherichia coli BW2952 stringent starvation protein A YP_002928126.1 3261952 R 595496 CDS YP_002928127.1 238902331 7956075 complement(3262985..3263377) 1 NC_012759.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3263377 rpsI 7956075 rpsI Escherichia coli BW2952 30S ribosomal protein S9 YP_002928127.1 3262985 R 595496 CDS YP_002928128.1 238902332 7952293 complement(3263393..3263821) 1 NC_012759.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3263821 rplM 7952293 rplM Escherichia coli BW2952 50S ribosomal protein L13 YP_002928128.1 3263393 R 595496 CDS YP_002928129.1 238902333 7952340 complement(3264040..3265167) 1 NC_012759.1 MG1655 equivalent: b3232; hypothetical protein 3265167 yhcM 7952340 yhcM Escherichia coli BW2952 hypothetical protein YP_002928129.1 3264040 R 595496 CDS YP_002928130.1 238902334 7953087 3265361..3265759 1 NC_012759.1 MG1655 equivalent: b3233; cytochrome d ubiquinol oxidase subunit III 3265759 yhcB 7953087 yhcB Escherichia coli BW2952 cytochrome d ubiquinol oxidase subunit III YP_002928130.1 3265361 D 595496 CDS YP_002928131.1 238902335 7953025 3265913..3267280 1 NC_012759.1 MG1655 equivalent: b3234; serine endoprotease 3267280 degQ 7953025 degQ Escherichia coli BW2952 serine endoprotease YP_002928131.1 3265913 D 595496 CDS YP_002928132.1 238902336 7956030 3267370..3268437 1 NC_012759.1 MG1655 equivalent: b3235; serine endoprotease 3268437 degS 7956030 degS Escherichia coli BW2952 serine endoprotease YP_002928132.1 3267370 D 595496 CDS YP_002928133.1 238902337 7956031 complement(3268500..3269438) 1 NC_012759.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3269438 mdh 7956031 mdh Escherichia coli BW2952 malate dehydrogenase YP_002928133.1 3268500 R 595496 CDS YP_002928134.1 238902338 7954199 3269873..3270343 1 NC_012759.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3270343 argR 7954199 argR Escherichia coli BW2952 arginine repressor YP_002928134.1 3269873 D 595496 CDS YP_002928135.1 238902339 7953433 3270708..3270971 1 NC_012759.1 MG1655 equivalent: b3238; hypothetical protein 3270971 yhcN 7953433 yhcN Escherichia coli BW2952 hypothetical protein YP_002928135.1 3270708 D 595496 CDS YP_002928136.1 238902340 7953026 complement(3271027..3271299) 1 NC_012759.1 MG1655 equivalent: b3239; putative barnase inhibitor 3271299 yhcO 7953026 yhcO Escherichia coli BW2952 putative barnase inhibitor YP_002928136.1 3271027 R 595496 CDS YP_002928137.1 238902341 7954666 complement(3271391..3273358) 1 NC_012759.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3273358 aaeB 7954666 aaeB Escherichia coli BW2952 p-hydroxybenzoic acid efflux subunit AaeB YP_002928137.1 3271391 R 595496 CDS YP_002928138.1 238902342 7954558 complement(3273364..3274296) 1 NC_012759.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3274296 aaeA 7954558 aaeA Escherichia coli BW2952 p-hydroxybenzoic acid efflux subunit AaeA YP_002928138.1 3273364 R 595496 CDS YP_002928139.1 238902343 7954559 complement(3274304..3274507) 1 NC_012759.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3274507 aaeX 7954559 aaeX Escherichia coli BW2952 hypothetical protein YP_002928139.1 3274304 R 595496 CDS YP_002928140.1 238902344 7954229 3274690..3275619 1 NC_012759.1 MG1655 equivalent: b3243; putative DNA-binding transcriptional regulator 3275619 aaeR 7954229 aaeR Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928140.1 3274690 D 595496 CDS YP_002928141.1 238902345 7954823 complement(3275753..3277198) 1 NC_012759.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3277198 tldD 7954823 tldD Escherichia coli BW2952 protease TldD YP_002928141.1 3275753 R 595496 CDS YP_002928142.1 238902346 7955278 complement(3277628..3281428) 1 NC_012759.1 MG1655 equivalent: b4472; hypothetical protein 3281428 yhdP 7955278 yhdP Escherichia coli BW2952 hypothetical protein YP_002928142.1 3277628 R 595496 CDS YP_002928143.1 238902347 7952744 complement(3281496..3282965) 1 NC_012759.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3282965 rng 7952744 rng Escherichia coli BW2952 ribonuclease G YP_002928143.1 3281496 R 595496 CDS YP_002928144.1 238902348 7955958 complement(3282955..3283548) 1 NC_012759.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3283548 yhdE 7955958 yhdE Escherichia coli BW2952 Maf-like protein YP_002928144.1 3282955 R 595496 CDS YP_002928145.1 238902349 7952874 complement(3283557..3284045) 1 NC_012759.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3284045 mreD 7952874 mreD Escherichia coli BW2952 rod shape-determining protein MreD YP_002928145.1 3283557 R 595496 CDS YP_002928146.1 238902350 7952621 complement(3284045..3285148) 1 NC_012759.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3285148 mreC 7952621 mreC Escherichia coli BW2952 rod shape-determining protein MreC YP_002928146.1 3284045 R 595496 CDS YP_002928147.1 238902351 7952620 complement(3285214..3286257) 1 NC_012759.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3286257 mreB 7952620 mreB Escherichia coli BW2952 rod shape-determining protein MreB YP_002928147.1 3285214 R 595496 CDS YP_002928148.1 238902352 7952622 complement(3286562..3288502) 1 NC_012759.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3288502 csrD 7952622 csrD Escherichia coli BW2952 regulatory protein CsrD YP_002928148.1 3286562 R 595496 CDS YP_002928149.1 238902353 7952686 3288654..3289628 1 NC_012759.1 MG1655 equivalent: b3253; putative oxidoreductase, Zn-dependent and NAD(P)-binding 3289628 yhdH 7952686 yhdH Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002928149.1 3288654 D 595496 CDS YP_002928150.1 238902354 7955265 3290606..3291076 1 NC_012759.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3291076 accB 7955265 accB Escherichia coli BW2952 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002928150.1 3290606 D 595496 CDS YP_002928151.1 238902355 7952395 3291087..3292436 1 NC_012759.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3292436 accC 7952395 accC Escherichia coli BW2952 acetyl-CoA carboxylase biotin carboxylase subunit YP_002928151.1 3291087 D 595496 CDS YP_002928152.1 238902356 7952400 3292545..3292787 1 NC_012759.1 MG1655 equivalent: b3257; hypothetical protein 3292787 yhdT 7952400 yhdT Escherichia coli BW2952 hypothetical protein YP_002928152.1 3292545 D 595496 CDS YP_002928153.1 238902357 7952723 3292777..3294228 1 NC_012759.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3294228 panF 7952723 panF Escherichia coli BW2952 sodium/panthothenate symporter YP_002928153.1 3292777 D 595496 CDS YP_002928154.1 238902358 7954466 3294240..3295121 1 NC_012759.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3295121 prmA 7954466 prmA Escherichia coli BW2952 50S ribosomal protein L11 methyltransferase YP_002928154.1 3294240 D 595496 CDS YP_002928155.1 238902359 7954252 3295450..3296415 1 NC_012759.1 MG1655 equivalent: b3260; tRNA-dihydrouridine synthase B 3296415 dusB 7954252 dusB Escherichia coli BW2952 tRNA-dihydrouridine synthase B YP_002928155.1 3295450 D 595496 CDS YP_002928156.1 238902360 7956205 3296441..3296737 1 NC_012759.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3296737 fis 7956205 fis Escherichia coli BW2952 DNA-binding protein Fis YP_002928156.1 3296441 D 595496 CDS YP_002928157.1 238902361 7953788 3296823..3297707 1 NC_012759.1 MG1655 equivalent: b3262; putative methyltransferase 3297707 yhdJ 7953788 yhdJ Escherichia coli BW2952 putative methyltransferase YP_002928157.1 3296823 D 595496 CDS YP_002928158.1 238902362 7955160 3297791..3297970 1 NC_012759.1 MG1655 equivalent: b3263; hypothetical protein 3297970 yhdU 7955160 yhdU Escherichia coli BW2952 hypothetical protein YP_002928158.1 3297791 D 595496 CDS YP_002928159.1 238902363 7955141 complement(3297973..3298635) 1 NC_012759.1 MG1655 equivalent: b3264; DNA-binding transcriptional regulator EnvR 3298635 envR 7955141 envR Escherichia coli BW2952 DNA-binding transcriptional regulator EnvR YP_002928159.1 3297973 R 595496 CDS YP_002928160.1 238902364 7953440 3299034..3300191 1 NC_012759.1 MG1655 equivalent: b3265; hypothetical protein 3300191 acrE 7953440 acrE Escherichia coli BW2952 hypothetical protein YP_002928160.1 3299034 D 595496 CDS YP_002928161.1 238902365 7953203 3300203..3303307 1 NC_012759.1 MG1655 equivalent: b3266; multidrug efflux system protein 3303307 acrF 7953203 acrF Escherichia coli BW2952 multidrug efflux system protein YP_002928161.1 3300203 D 595496 CDS YP_002928162.1 238902366 7954304 3303560..3303781 1 NC_012759.1 MG1655 equivalent: b3267; putative outer membrane protein 3303781 yhdV 7954304 yhdV Escherichia coli BW2952 putative outer membrane protein YP_002928162.1 3303560 D 595496 CDS YP_002928163.1 238902367 7955215 3305304..3306485 1 NC_012759.1 MG1655 equivalent: b3269; putative amino-acid transporter subunit 3306485 yhdX 7955215 yhdX Escherichia coli BW2952 putative amino-acid transporter subunit YP_002928163.1 3305304 D 595496 CDS YP_002928164.1 238902368 7954642 3306495..3307598 1 NC_012759.1 MG1655 equivalent: b3270; putative amino-acid transporter subunit 3307598 yhdY 7954642 yhdY Escherichia coli BW2952 putative amino-acid transporter subunit YP_002928164.1 3306495 D 595496 CDS YP_002928165.1 238902369 7954643 3307606..3308364 1 NC_012759.1 MG1655 equivalent: b3271; putative amino-acid transporter subunit 3308364 yhdZ 7954643 yhdZ Escherichia coli BW2952 putative amino-acid transporter subunit YP_002928165.1 3307606 D 595496 CDS YP_002928166.1 238902370 7952040 3314415..3314969 1 NC_012759.1 MG1655 equivalent: b3279; hypothetical protein 3314969 yrdA 7952040 yrdA Escherichia coli BW2952 hypothetical protein YP_002928166.1 3314415 D 595496 CDS YP_002928167.1 238902371 7953027 complement(3314945..3315202) 1 NC_012759.1 MG1655 equivalent: b3280; hypothetical protein 3315202 yrdB 7953027 yrdB Escherichia coli BW2952 hypothetical protein YP_002928167.1 3314945 R 595496 CDS YP_002928168.1 238902372 7952875 complement(3315199..3316017) 1 NC_012759.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3316017 aroE 7952875 aroE Escherichia coli BW2952 shikimate 5-dehydrogenase YP_002928168.1 3315199 R 595496 CDS YP_002928169.1 238902373 7953232 complement(3316022..3316594) 1 NC_012759.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor 3316594 rimN 7953232 rimN Escherichia coli BW2952 putative ribosome maturation factor YP_002928169.1 3316022 R 595496 CDS YP_002928170.1 238902374 7955570 complement(3316599..3317141) 1 NC_012759.1 MG1655 equivalent: b3283; putative DNA topoisomerase 3317141 yrdD 7955570 yrdD Escherichia coli BW2952 putative DNA topoisomerase YP_002928170.1 3316599 R 595496 CDS YP_002928171.1 238902375 7954737 complement(3317170..3317643) 1 NC_012759.1 MG1655 equivalent: b3284; hypothetical protein 3317643 smg 7954737 smg Escherichia coli BW2952 hypothetical protein YP_002928171.1 3317170 R 595496 CDS YP_002928172.1 238902376 7952876 complement(3317615..3318739) 1 NC_012759.1 MG1655 equivalent: b4473; DNA protecting protein DprA 3318739 smf 7952876 smf Escherichia coli BW2952 DNA protecting protein DprA YP_002928172.1 3317615 R 595496 CDS YP_002928173.1 238902377 7952911 3318869..3319378 1 NC_012759.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3319378 def 7952911 def Escherichia coli BW2952 peptide deformylase YP_002928173.1 3318869 D 595496 CDS YP_002928174.1 238902378 7954477 3319393..3320340 1 NC_012759.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3320340 fmt 7954477 fmt Escherichia coli BW2952 methionyl-tRNA formyltransferase YP_002928174.1 3319393 D 595496 CDS YP_002928175.1 238902379 7952221 3320386..3321675 1 NC_012759.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3321675 rsmB 7952221 rsmB Escherichia coli BW2952 16S rRNA methyltransferase B YP_002928175.1 3320386 D 595496 CDS YP_002928176.1 238902380 7952223 3321697..3323073 1 NC_012759.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3323073 trkA 7952223 trkA Escherichia coli BW2952 potassium transporter peripheral membrane protein YP_002928176.1 3321697 D 595496 CDS YP_002928177.1 238902381 7954353 3323203..3323613 1 NC_012759.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3323613 mscL 7954353 mscL Escherichia coli BW2952 large-conductance mechanosensitive channel YP_002928177.1 3323203 D 595496 CDS YP_002928178.1 238902382 7954219 complement(3323610..3323828) 1 NC_012759.1 MG1655 equivalent: b4550; hypothetical protein 3323828 yhdL 7954219 yhdL Escherichia coli BW2952 hypothetical protein YP_002928178.1 3323610 R 595496 CDS YP_002928179.1 238902383 7952912 complement(3323884..3324309) 1 NC_012759.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3324309 zntR 7952912 zntR Escherichia coli BW2952 zinc-responsive transcriptional regulator YP_002928179.1 3323884 R 595496 CDS YP_002928180.1 238902384 7953385 complement(3324320..3324688) 1 NC_012759.1 MG1655 equivalent: b3293; hypothetical protein 3324688 yhdN 7953385 yhdN Escherichia coli BW2952 hypothetical protein YP_002928180.1 3324320 R 595496 CDS YP_002928181.1 238902385 7952877 complement(3324795..3325178) 1 NC_012759.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3325178 rplQ 7952877 rplQ Escherichia coli BW2952 50S ribosomal protein L17 YP_002928181.1 3324795 R 595496 CDS YP_002928182.1 238902386 7952344 complement(3325219..3326208) 1 NC_012759.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3326208 rpoA 7952344 rpoA Escherichia coli BW2952 DNA-directed RNA polymerase subunit alpha YP_002928182.1 3325219 R 595496 CDS YP_002928183.1 238902387 7955983 complement(3326234..3326854) 1 NC_012759.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3326854 rpsD 7955983 rpsD Escherichia coli BW2952 30S ribosomal protein S4 YP_002928183.1 3326234 R 595496 CDS YP_002928184.1 238902388 7952288 complement(3326888..3327277) 1 NC_012759.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3327277 rpsK 7952288 rpsK Escherichia coli BW2952 30S ribosomal protein S11 YP_002928184.1 3326888 R 595496 CDS YP_002928185.1 238902389 7952274 complement(3327294..3327650) 1 NC_012759.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3327650 rpsM 7952274 rpsM Escherichia coli BW2952 30S ribosomal protein S13 YP_002928185.1 3327294 R 595496 CDS YP_002928186.1 238902390 7952276 complement(3327797..3327913) 1 NC_012759.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3327913 rpmJ 7952276 rpmJ Escherichia coli BW2952 50S ribosomal protein L36 YP_002928186.1 3327797 R 595496 CDS YP_002928187.1 238902391 7952364 complement(3327945..3329276) 1 NC_012759.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3329276 secY 7952364 secY Escherichia coli BW2952 preprotein translocase subunit SecY YP_002928187.1 3327945 R 595496 CDS YP_002928188.1 238902392 7955761 complement(3329284..3329718) 1 NC_012759.1 late assembly protein; 50S ribosomal protein L15 3329718 rplO 7955761 rplO Escherichia coli BW2952 50S ribosomal protein L15 YP_002928188.1 3329284 R 595496 CDS YP_002928189.1 238902393 7952342 complement(3329722..3329901) 1 NC_012759.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3329901 rpmD 7952342 rpmD Escherichia coli BW2952 50S ribosomal protein L30 YP_002928189.1 3329722 R 595496 CDS YP_002928190.1 238902394 7952358 complement(3329905..3330408) 1 NC_012759.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3330408 rpsE 7952358 rpsE Escherichia coli BW2952 30S ribosomal protein S5 YP_002928190.1 3329905 R 595496 CDS YP_002928191.1 238902395 7952289 complement(3330423..3330776) 1 NC_012759.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3330776 rplR 7952289 rplR Escherichia coli BW2952 50S ribosomal protein L18 YP_002928191.1 3330423 R 595496 CDS YP_002928192.1 238902396 7952345 complement(3330786..3331319) 1 NC_012759.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3331319 rplF 7952345 rplF Escherichia coli BW2952 50S ribosomal protein L6 YP_002928192.1 3330786 R 595496 CDS YP_002928193.1 238902397 7952367 complement(3331332..3331724) 1 NC_012759.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3331724 rpsH 7952367 rpsH Escherichia coli BW2952 30S ribosomal protein S8 YP_002928193.1 3331332 R 595496 CDS YP_002928194.1 238902398 7952292 complement(3331758..3332063) 1 NC_012759.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3332063 rpsN 7952292 rpsN Escherichia coli BW2952 30S ribosomal protein S14 YP_002928194.1 3331758 R 595496 CDS YP_002928195.1 238902399 7952277 complement(3332078..3332617) 1 NC_012759.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3332617 rplE 7952277 rplE Escherichia coli BW2952 50S ribosomal protein L5 YP_002928195.1 3332078 R 595496 CDS YP_002928196.1 238902400 7952366 complement(3332632..3332946) 1 NC_012759.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3332946 rplX 7952366 rplX Escherichia coli BW2952 50S ribosomal protein L24 YP_002928196.1 3332632 R 595496 CDS YP_002928197.1 238902401 7952352 complement(3332957..3333328) 1 NC_012759.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3333328 rplN 7952352 rplN Escherichia coli BW2952 50S ribosomal protein L14 YP_002928197.1 3332957 R 595496 CDS YP_002928198.1 238902402 7952341 complement(3333493..3333747) 1 NC_012759.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3333747 rpsQ 7952341 rpsQ Escherichia coli BW2952 30S ribosomal protein S17 YP_002928198.1 3333493 R 595496 CDS YP_002928199.1 238902403 7952280 complement(3333747..3333938) 1 NC_012759.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3333938 rpmC 7952280 rpmC Escherichia coli BW2952 50S ribosomal protein L29 YP_002928199.1 3333747 R 595496 CDS YP_002928200.1 238902404 7952356 complement(3333938..3334348) 1 NC_012759.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3334348 rplP 7952356 rplP Escherichia coli BW2952 50S ribosomal protein L16 YP_002928200.1 3333938 R 595496 CDS YP_002928201.1 238902405 7952343 complement(3334361..3335062) 1 NC_012759.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3335062 rpsC 7952343 rpsC Escherichia coli BW2952 30S ribosomal protein S3 YP_002928201.1 3334361 R 595496 CDS YP_002928202.1 238902406 7952287 complement(3335080..3335412) 1 NC_012759.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3335412 rplV 7952287 rplV Escherichia coli BW2952 50S ribosomal protein L22 YP_002928202.1 3335080 R 595496 CDS YP_002928203.1 238902407 7952350 complement(3335427..3335705) 1 NC_012759.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3335705 rpsS 7952350 rpsS Escherichia coli BW2952 30S ribosomal protein S19 YP_002928203.1 3335427 R 595496 CDS YP_002928204.1 238902408 7952282 complement(3335722..3336543) 1 NC_012759.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3336543 rplB 7952282 rplB Escherichia coli BW2952 50S ribosomal protein L2 YP_002928204.1 3335722 R 595496 CDS YP_002928205.1 238902409 7952347 complement(3336561..3336863) 1 NC_012759.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3336863 rplW 7952347 rplW Escherichia coli BW2952 50S ribosomal protein L23 YP_002928205.1 3336561 R 595496 CDS YP_002928206.1 238902410 7952351 complement(3336860..3337465) 1 NC_012759.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3337465 rplD 7952351 rplD Escherichia coli BW2952 50S ribosomal protein L4 YP_002928206.1 3336860 R 595496 CDS YP_002928207.1 238902411 7952365 complement(3337476..3338105) 1 NC_012759.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3338105 rplC 7952365 rplC Escherichia coli BW2952 50S ribosomal protein L3 YP_002928207.1 3337476 R 595496 CDS YP_002928208.1 238902412 7952357 complement(3338138..3338449) 1 NC_012759.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3338449 rpsJ 7952357 rpsJ Escherichia coli BW2952 30S ribosomal protein S10 YP_002928208.1 3338138 R 595496 CDS YP_002928209.1 238902413 7952273 complement(3338687..3339106) 1 NC_012759.1 calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 3339106 gspB 7952273 gspB Escherichia coli BW2952 chromosome replication protein PioO YP_002928209.1 3338687 R 595496 CDS YP_002928210.1 238902414 7954470 complement(3339108..3340577) 1 NC_012759.1 MG1655 equivalent: b3323; general secretory pathway component, cryptic 3340577 gspA 7954470 gspA Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928210.1 3339108 R 595496 CDS YP_002928211.1 238902415 7953778 3340757..3341572 1 NC_012759.1 MG1655 equivalent: b3324; general secretory pathway component, cryptic 3341572 gspC 7953778 gspC Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928211.1 3340757 D 595496 CDS YP_002928212.1 238902416 7953779 3341556..3343508 1 NC_012759.1 MG1655 equivalent: b3325; general secretory pathway component, cryptic 3343508 gspD 7953779 gspD Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928212.1 3341556 D 595496 CDS YP_002928213.1 238902417 7953780 3343518..3344999 1 NC_012759.1 MG1655 equivalent: b3326; general secretory pathway component, cryptic 3344999 gspE 7953780 gspE Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928213.1 3343518 D 595496 CDS YP_002928214.1 238902418 7953781 3344996..3346192 1 NC_012759.1 MG1655 equivalent: b3327; general secretory pathway component, cryptic 3346192 gspF 7953781 gspF Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928214.1 3344996 D 595496 CDS YP_002928215.1 238902419 7953782 3346202..3346639 1 NC_012759.1 MG1655 equivalent: b3328; pseudopilin, cryptic, general secretion pathway 3346639 gspG 7953782 gspG Escherichia coli BW2952 pseudopilin, cryptic, general secretion pathway YP_002928215.1 3346202 D 595496 CDS YP_002928216.1 238902420 7955818 3346647..3347156 1 NC_012759.1 MG1655 equivalent: b3329; putative general secretory pathway component, cryptic 3347156 gspH 7955818 gspH Escherichia coli BW2952 putative general secretory pathway component, cryptic YP_002928216.1 3346647 D 595496 CDS YP_002928217.1 238902421 7954915 3347153..3347530 1 NC_012759.1 MG1655 equivalent: b3330; general secretory pathway component, cryptic 3347530 gspI 7954915 gspI Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928217.1 3347153 D 595496 CDS YP_002928218.1 238902422 7953783 3347523..3348110 1 NC_012759.1 MG1655 equivalent: b3331; putative general secretory pathway component, cryptic 3348110 gspJ 7953783 gspJ Escherichia coli BW2952 putative general secretory pathway component, cryptic YP_002928218.1 3347523 D 595496 CDS YP_002928219.1 238902423 7954916 3348103..3349086 1 NC_012759.1 MG1655 equivalent: b3332; general secretory pathway component, cryptic 3349086 gspK 7954916 gspK Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928219.1 3348103 D 595496 CDS YP_002928220.1 238902424 7953784 3349101..3350264 1 NC_012759.1 MG1655 equivalent: b3333; general secretory pathway component, cryptic 3350264 gspL 7953784 gspL Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928220.1 3349101 D 595496 CDS YP_002928221.1 238902425 7953785 3350261..3350722 1 NC_012759.1 MG1655 equivalent: b3334; general secretory pathway component, cryptic 3350722 gspM 7953785 gspM Escherichia coli BW2952 general secretory pathway component, cryptic YP_002928221.1 3350261 D 595496 CDS YP_002928222.1 238902426 7953786 3350722..3351399 1 NC_012759.1 MG1655 equivalent: b3335; bifunctional prepilin leader peptidase/ methylase 3351399 gspO 7953786 gspO Escherichia coli BW2952 bifunctional prepilin leader peptidase/ methylase YP_002928222.1 3350722 D 595496 CDS YP_002928223.1 238902427 7952572 complement(3351428..3351904) 1 NC_012759.1 iron storage protein; bacterioferritin 3351904 bfr 7952572 bfr Escherichia coli BW2952 bacterioferritin YP_002928223.1 3351428 R 595496 CDS YP_002928224.1 238902428 7952541 complement(3351976..3352170) 1 NC_012759.1 MG1655 equivalent: b3337; bacterioferritin-associated ferredoxin 3352170 bfd 7952541 bfd Escherichia coli BW2952 bacterioferritin-associated ferredoxin YP_002928224.1 3351976 R 595496 CDS YP_002928225.1 238902429 7952542 complement(3352339..3355032) 1 NC_012759.1 MG1655 equivalent: b3338; periplasmic endochitinase 3355032 chiA 7952542 chiA Escherichia coli BW2952 periplasmic endochitinase YP_002928225.1 3352339 R 595496 CDS YP_002928226.1 238902430 7954490 complement(3355324..3356508) 1 NC_012759.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3356508 tufA 7954490 tufA Escherichia coli BW2952 elongation factor Tu YP_002928226.1 3355324 R 595496 CDS YP_002928227.1 238902431 7955788 complement(3356579..3358693) 1 NC_012759.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3358693 fusA 7955788 fusA Escherichia coli BW2952 elongation factor G YP_002928227.1 3356579 R 595496 CDS YP_002928228.1 238902432 7955785 complement(3358721..3359260) 1 NC_012759.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3359260 rpsG 7955785 rpsG Escherichia coli BW2952 30S ribosomal protein S7 YP_002928228.1 3358721 R 595496 CDS YP_002928229.1 238902433 7952291 complement(3359357..3359731) 1 NC_012759.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3359731 rpsL 7952291 rpsL Escherichia coli BW2952 30S ribosomal protein S12 YP_002928229.1 3359357 R 595496 CDS YP_002928230.1 238902434 7952275 complement(3359857..3360144) 1 NC_012759.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3360144 yheL 7952275 yheL Escherichia coli BW2952 sulfur transfer complex subunit TusB YP_002928230.1 3359857 R 595496 CDS YP_002928231.1 238902435 7955081 complement(3360152..3360511) 1 NC_012759.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3360511 yheM 7955081 yheM Escherichia coli BW2952 sulfur relay protein TusC YP_002928231.1 3360152 R 595496 CDS YP_002928232.1 238902436 7955083 complement(3360511..3360897) 1 NC_012759.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3360897 yheN 7955083 yheN Escherichia coli BW2952 sulfur transfer complex subunit TusD YP_002928232.1 3360511 R 595496 CDS YP_002928233.1 238902437 7955082 complement(3360897..3361619) 1 NC_012759.1 MG1655 equivalent: b3346; putative DNA-binding transcriptional regulator 3361619 yheO 7955082 yheO Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928233.1 3360897 R 595496 CDS YP_002928234.1 238902438 7954783 complement(3361786..3362598) 1 NC_012759.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3362598 fkpA 7954783 fkpA Escherichia coli BW2952 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002928234.1 3361786 R 595496 CDS YP_002928235.1 238902439 7953579 3362819..3363037 1 NC_012759.1 MG1655 equivalent: b3348; hypothetical protein 3363037 slyX 7953579 slyX Escherichia coli BW2952 hypothetical protein YP_002928235.1 3362819 D 595496 CDS YP_002928236.1 238902440 7953028 complement(3363086..3363676) 1 NC_012759.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3363676 slyD 7953028 slyD Escherichia coli BW2952 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002928236.1 3363086 R 595496 CDS YP_002928237.1 238902441 7953578 complement(3363771..3363971) 1 NC_012759.1 MG1655 equivalent: b4551; hypothetical protein 3363971 yheV 7953578 yheV Escherichia coli BW2952 hypothetical protein YP_002928237.1 3363771 R 595496 CDS YP_002928238.1 238902442 7955435 complement(3363981..3365786) 1 NC_012759.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3365786 kefB 7955435 kefB Escherichia coli BW2952 glutathione-regulated potassium-efflux system protein KefB YP_002928238.1 3363981 R 595496 CDS YP_002928239.1 238902443 7954578 complement(3365786..3366340) 1 NC_012759.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3366340 kefG 7954578 kefG Escherichia coli BW2952 glutathione-regulated potassium-efflux system ancillary protein KefG YP_002928239.1 3365786 R 595496 CDS YP_002928240.1 238902444 7952656 3366468..3368381 1 NC_012759.1 MG1655 equivalent: b3352; putative ABC transporter ATP-binding protein 3368381 yheS 7952656 yheS Escherichia coli BW2952 putative ABC transporter ATP-binding protein YP_002928240.1 3366468 D 595496 CDS YP_002928241.1 238902445 7953734 3368381..3369403 1 NC_012759.1 MG1655 equivalent: b3353; putative hydrolase 3369403 yheT 7953734 yheT Escherichia coli BW2952 putative hydrolase YP_002928241.1 3368381 D 595496 CDS YP_002928242.1 238902446 7954969 3369397..3369615 1 NC_012759.1 MG1655 equivalent: b3354; hypothetical protein 3369615 yheU 7954969 yheU Escherichia coli BW2952 hypothetical protein YP_002928242.1 3369397 D 595496 CDS YP_002928243.1 238902447 7953029 3369669..3370538 1 NC_012759.1 MG1655 equivalent: b3355; putative phosphoribulokinase 3370538 prkB 7953029 prkB Escherichia coli BW2952 putative phosphoribulokinase YP_002928243.1 3369669 D 595496 CDS YP_002928244.1 238902448 7955318 complement(3370593..3370997) 1 NC_012759.1 MG1655 equivalent: b3356; hypothetical protein 3370997 yhfA 7955318 yhfA Escherichia coli BW2952 hypothetical protein YP_002928244.1 3370593 R 595496 CDS YP_002928245.1 238902449 7952878 3371299..3371931 1 NC_012759.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3371931 crp 7952878 crp Escherichia coli BW2952 cAMP-regulatory protein YP_002928245.1 3371299 D 595496 CDS YP_002928246.1 238902450 7953423 3371970..3374072 1 NC_012759.1 MG1655 equivalent: b3358; hypothetical protein 3374072 yhfK 7953423 yhfK Escherichia coli BW2952 hypothetical protein YP_002928246.1 3371970 D 595496 CDS YP_002928247.1 238902451 7952724 complement(3374139..3375359) 1 NC_012759.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 3375359 argD 7952724 argD Escherichia coli BW2952 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_002928247.1 3374139 R 595496 CDS YP_002928248.1 238902452 7952560 complement(3375445..3376008) 1 NC_012759.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3376008 pabA 7952560 pabA Escherichia coli BW2952 para-aminobenzoate synthase component II YP_002928248.1 3375445 R 595496 CDS YP_002928249.1 238902453 7952466 complement(3376040..3376642) 1 NC_012759.1 MG1655 equivalent: b3361; cell filamentation protein Fic 3376642 fic 7952466 fic Escherichia coli BW2952 cell filamentation protein Fic YP_002928249.1 3376040 R 595496 CDS YP_002928250.1 238902454 7956068 complement(3376632..3376799) 1 NC_012759.1 MG1655 equivalent: b3362; hypothetical protein 3376799 yhfG 7956068 yhfG Escherichia coli BW2952 hypothetical protein YP_002928250.1 3376632 R 595496 CDS YP_002928251.1 238902455 7955417 complement(3376904..3377476) 1 NC_012759.1 MG1655 equivalent: b3363; peptidyl-prolyl cis-trans isomerase A 3377476 ppiA 7955417 ppiA Escherichia coli BW2952 peptidyl-prolyl cis-trans isomerase A YP_002928251.1 3376904 R 595496 CDS YP_002928252.1 238902456 7954482 3377747..3378928 1 NC_012759.1 MG1655 equivalent: b3364; hypothetical protein 3378928 tsgA 7954482 tsgA Escherichia coli BW2952 hypothetical protein YP_002928252.1 3377747 D 595496 CDS YP_002928253.1 238902457 7955704 3379190..3381733 1 NC_012759.1 MG1655 equivalent: b3365; nitrite reductase, large subunit, NAD(P)H-binding 3381733 nirB 7955704 nirB Escherichia coli BW2952 nitrite reductase, large subunit, NAD(P)H-binding YP_002928253.1 3379190 D 595496 CDS YP_002928254.1 238902458 7954401 3381730..3382056 1 NC_012759.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3382056 nirD 7954401 nirD Escherichia coli BW2952 nitrite reductase small subunit YP_002928254.1 3381730 D 595496 CDS YP_002928255.1 238902459 7954402 3382182..3382988 1 NC_012759.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3382988 nirC 7954402 nirC Escherichia coli BW2952 nitrite transporter NirC YP_002928255.1 3382182 D 595496 CDS YP_002928256.1 238902460 7954403 3383007..3384380 1 NC_012759.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3384380 cysG 7954403 cysG Escherichia coli BW2952 siroheme synthase YP_002928256.1 3383007 D 595496 CDS YP_002928257.1 238902461 7953744 3384627..3384794 1 NC_012759.1 MG1655 equivalent: b3369; hypothetical protein 3384794 yhfL 7953744 yhfL Escherichia coli BW2952 hypothetical protein YP_002928257.1 3384627 D 595496 CDS YP_002928258.1 238902462 7953094 3385089..3386426 1 NC_012759.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter 3386426 frlA 7953094 frlA Escherichia coli BW2952 putative fructoselysine transporter YP_002928258.1 3385089 D 595496 CDS YP_002928259.1 238902463 7954913 3386447..3387469 1 NC_012759.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 3387469 frlB 7954913 frlB Escherichia coli BW2952 fructoselysine-6-P-deglycase YP_002928259.1 3386447 D 595496 CDS YP_002928260.1 238902464 7953640 3387519..3388349 1 NC_012759.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 3388349 frlC 7953640 frlC Escherichia coli BW2952 fructoselysine 3-epimerase YP_002928260.1 3387519 D 595496 CDS YP_002928261.1 238902465 7955090 3388346..3389131 1 NC_012759.1 MG1655 equivalent: b3374; fructoselysine 6-kinase 3389131 frlD 7955090 frlD Escherichia coli BW2952 fructoselysine 6-kinase YP_002928261.1 3388346 D 595496 CDS YP_002928262.1 238902466 7953639 3389231..3389962 1 NC_012759.1 may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3389962 frlR 7953639 frlR Escherichia coli BW2952 DNA-binding transcriptional regulator FrlR YP_002928262.1 3389231 D 595496 CDS YP_002928263.1 238902467 7954809 complement(3390114..3391199) 1 NC_012759.1 MG1655 equivalent: b3376; hypothetical protein 3391199 yhfS 7954809 yhfS Escherichia coli BW2952 hypothetical protein YP_002928263.1 3390114 R 595496 CDS YP_002928264.1 238902468 7952879 complement(3391211..3392515) 1 NC_012759.1 MG1655 equivalent: b3377; putative inner membrane protein 3392515 yhfT 7952879 yhfT Escherichia coli BW2952 putative inner membrane protein YP_002928264.1 3391211 R 595496 CDS YP_002928265.1 238902469 7955010 complement(3392527..3392880) 1 NC_012759.1 MG1655 equivalent: b3378; hypothetical protein 3392880 yhfU 7955010 yhfU Escherichia coli BW2952 hypothetical protein YP_002928265.1 3392527 R 595496 CDS YP_002928266.1 238902470 7955418 complement(3392891..3393769) 1 NC_012759.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase 3393769 php 7955418 php Escherichia coli BW2952 putative hydrolase YP_002928266.1 3392891 R 595496 CDS YP_002928267.1 238902471 7954960 complement(3393766..3394992) 1 NC_012759.1 MG1655 equivalent: b3380; putative mutase 3394992 yhfW 7954960 yhfW Escherichia coli BW2952 putative mutase YP_002928267.1 3393766 R 595496 CDS YP_002928268.1 238902472 7955176 complement(3394992..3396155) 1 NC_012759.1 MG1655 equivalent: b3381; putative amino acid racemase 3396155 yhfX 7955176 yhfX Escherichia coli BW2952 putative amino acid racemase YP_002928268.1 3394992 R 595496 CDS YP_002928269.1 238902473 7954640 complement(3396239..3396601) 1 NC_012759.1 MG1655 equivalent: b3382; hypothetical protein 3396601 yhfY 7954640 yhfY Escherichia coli BW2952 hypothetical protein YP_002928269.1 3396239 R 595496 CDS YP_002928270.1 238902474 7952880 complement(3396618..3397523) 1 NC_012759.1 MG1655 equivalent: b3383; hypothetical protein 3397523 yhfZ 7952880 yhfZ Escherichia coli BW2952 hypothetical protein YP_002928270.1 3396618 R 595496 CDS YP_002928271.1 238902475 7952881 complement(3397813..3398817) 1 NC_012759.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3398817 trpS 7952881 trpS Escherichia coli BW2952 tryptophanyl-tRNA synthetase YP_002928271.1 3397813 R 595496 CDS YP_002928272.1 238902476 7956217 complement(3398810..3399568) 1 NC_012759.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3399568 gph 7956217 gph Escherichia coli BW2952 phosphoglycolate phosphatase YP_002928272.1 3398810 R 595496 CDS YP_002928273.1 238902477 7954538 complement(3399561..3400238) 1 NC_012759.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3400238 rpe 7954538 rpe Escherichia coli BW2952 ribulose-phosphate 3-epimerase YP_002928273.1 3399561 R 595496 CDS YP_002928274.1 238902478 7953495 complement(3400256..3401092) 1 NC_012759.1 MG1655 equivalent: b3387; DNA adenine methylase 3401092 dam 7953495 dam Escherichia coli BW2952 DNA adenine methylase YP_002928274.1 3400256 R 595496 CDS YP_002928275.1 238902479 7953298 complement(3401199..3402485) 1 NC_012759.1 MG1655 equivalent: b3388; hypothetical protein 3402485 damX 7953298 damX Escherichia coli BW2952 hypothetical protein YP_002928275.1 3401199 R 595496 CDS YP_002928276.1 238902480 7955419 complement(3402577..3403665) 1 NC_012759.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3403665 aroB 7955419 aroB Escherichia coli BW2952 3-dehydroquinate synthase YP_002928276.1 3402577 R 595496 CDS YP_002928277.1 238902481 7952296 complement(3403722..3404243) 1 NC_012759.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3404243 aroK 7952296 aroK Escherichia coli BW2952 shikimate kinase I YP_002928277.1 3403722 R 595496 CDS YP_002928278.1 238902482 7956037 complement(3404644..3405882) 1 NC_012759.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3405882 hofQ 7956037 hofQ Escherichia coli BW2952 outer membrane porin HofQ YP_002928278.1 3404644 R 595496 CDS YP_002928279.1 238902483 7954875 complement(3405794..3406198) 1 NC_012759.1 MG1655 equivalent: b3392; hypothetical protein 3406198 hofP 7954875 hofP Escherichia coli BW2952 hypothetical protein YP_002928279.1 3405794 R 595496 CDS YP_002928280.1 238902484 7955420 complement(3406188..3406628) 1 NC_012759.1 MG1655 equivalent: b3393; hypothetical protein 3406628 hofO 7955420 hofO Escherichia coli BW2952 hypothetical protein YP_002928280.1 3406188 R 595496 CDS YP_002928281.1 238902485 7952743 complement(3406612..3407151) 1 NC_012759.1 MG1655 equivalent: b3394; putative fimbrial assembly protein 3407151 hofN 7952743 hofN Escherichia coli BW2952 putative fimbrial assembly protein YP_002928281.1 3406612 R 595496 CDS YP_002928282.1 238902486 7954874 complement(3407151..3407930) 1 NC_012759.1 MG1655 equivalent: b3395; putative pilus assembly protein 3407930 hofM 7954874 hofM Escherichia coli BW2952 putative pilus assembly protein YP_002928282.1 3407151 R 595496 CDS YP_002928283.1 238902487 7955322 3408050..3410602 1 NC_012759.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3410602 mrcA 7955322 mrcA Escherichia coli BW2952 peptidoglycan synthetase YP_002928283.1 3408050 D 595496 CDS YP_002928284.1 238902488 7953705 complement(3410768..3411328) 1 NC_012759.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3411328 nudE 7953705 nudE Escherichia coli BW2952 ADP-ribose diphosphatase NudE YP_002928284.1 3410768 R 595496 CDS YP_002928285.1 238902489 7952432 3411648..3413783 1 NC_012759.1 MG1655 equivalent: b3398; putative inner membrane protein 3413783 yrfF 7952432 yrfF Escherichia coli BW2952 putative inner membrane protein YP_002928285.1 3411648 D 595496 CDS YP_002928286.1 238902490 7955066 3413848..3414516 1 NC_012759.1 MG1655 equivalent: b3399; putative hydrolase 3414516 yrfG 7955066 yrfG Escherichia coli BW2952 putative hydrolase YP_002928286.1 3413848 D 595496 CDS YP_002928287.1 238902491 7954970 3414527..3414928 1 NC_012759.1 MG1655 equivalent: b3400; ribosome-associated heat shock protein Hsp15 3414928 hslR 7954970 hslR Escherichia coli BW2952 ribosome-associated heat shock protein Hsp15 YP_002928287.1 3414527 D 595496 CDS YP_002928288.1 238902492 7955980 3414953..3415831 1 NC_012759.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3415831 hslO 7955980 hslO Escherichia coli BW2952 Hsp33-like chaperonin YP_002928288.1 3414953 D 595496 CDS YP_002928289.1 238902493 7953894 complement(3415894..3417618) 1 NC_012759.1 MG1655 equivalent: b3402; putative inner membrane protein 3417618 yhgE 7953894 yhgE Escherichia coli BW2952 putative inner membrane protein YP_002928289.1 3415894 R 595496 CDS YP_002928290.1 238902494 7955011 3417997..3419619 1 NC_012759.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3419619 pck 7955011 pck Escherichia coli BW2952 phosphoenolpyruvate carboxykinase YP_002928290.1 3417997 D 595496 CDS YP_002928291.1 238902495 7954528 complement(3419695..3421047) 1 NC_012759.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3421047 envZ 7954528 envZ Escherichia coli BW2952 osmolarity sensor protein YP_002928291.1 3419695 R 595496 CDS YP_002928292.1 238902496 7956022 complement(3421044..3421763) 1 NC_012759.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3421763 ompR 7956022 ompR Escherichia coli BW2952 osmolarity response regulator YP_002928292.1 3421044 R 595496 CDS YP_002928293.1 238902497 7953352 3421991..3422467 1 NC_012759.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3422467 greB 7953352 greB Escherichia coli BW2952 transcription elongation factor GreB YP_002928293.1 3421991 D 595496 CDS YP_002928294.1 238902498 7956168 3422564..3424885 1 NC_012759.1 MG1655 equivalent: b3407; putative transcriptional accessory protein 3424885 yhgF 7956168 yhgF Escherichia coli BW2952 putative transcriptional accessory protein YP_002928294.1 3422564 D 595496 CDS YP_002928295.1 238902499 7955628 3425342..3425569 1 NC_012759.1 MG1655 equivalent: b3408; ferrous iron transport protein A 3425569 feoA 7955628 feoA Escherichia coli BW2952 ferrous iron transport protein A YP_002928295.1 3425342 D 595496 CDS YP_002928296.1 238902500 7953574 3425586..3427907 1 NC_012759.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3427907 feoB 7953574 feoB Escherichia coli BW2952 ferrous iron transport protein B YP_002928296.1 3425586 D 595496 CDS YP_002928297.1 238902501 7953680 3427907..3428143 1 NC_012759.1 MG1655 equivalent: b3410; putative DNA-binding transcriptional regulator 3428143 feoC 7953680 feoC Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928297.1 3427907 D 595496 CDS YP_002928298.1 238902502 7954810 3428346..3429224 1 NC_012759.1 MG1655 equivalent: b3411; hypothetical protein 3429224 yhgA 7954810 yhgA Escherichia coli BW2952 hypothetical protein YP_002928298.1 3428346 D 595496 CDS YP_002928299.1 238902503 7955741 complement(3429253..3430023) 1 NC_012759.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3430023 bioH 7955741 bioH Escherichia coli BW2952 carboxylesterase BioH YP_002928299.1 3429253 R 595496 CDS YP_002928300.1 238902504 7952606 3430061..3430744 1 NC_012759.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3430744 gntX 7952606 gntX Escherichia coli BW2952 gluconate periplasmic binding protein YP_002928300.1 3430061 D 595496 CDS YP_002928301.1 238902505 7953798 3430803..3431378 1 NC_012759.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 3431378 gntY 7953798 gntY Escherichia coli BW2952 putative DNA uptake protein YP_002928301.1 3430803 D 595496 CDS YP_002928302.1 238902506 7954918 3431849..3432214 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3432214 7954918 BWG_3106 Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002928302.1 3431849 D 595496 CDS YP_002928303.1 238902507 7954007 3432172..3432567 1 NC_012759.1 insertion element IS2 transposase InsD 3432567 7954007 BWG_3107 Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002928303.1 3432172 D 595496 CDS YP_002928304.1 238902508 7954005 3432536..3433078 1 NC_012759.1 OSJNBa0065H10.1 protein 3433078 7954005 BWG_3108 Escherichia coli BW2952 OSJNBa0065H10.1 protein YP_002928304.1 3432536 D 595496 CDS YP_002928305.1 238902509 7954433 3433063..3434391 1 NC_012759.1 MG1655 equivalent: b3415; gluconate transporter, high-affinity GNT I system 3434391 gntT 7954433 gntT Escherichia coli BW2952 gluconate transporter, high-affinity GNT I system YP_002928305.1 3433063 D 595496 CDS YP_002928306.1 238902510 7953799 complement(3434502..3436586) 1 NC_012759.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3436586 malQ 7953799 malQ Escherichia coli BW2952 4-alpha-glucanotransferase YP_002928306.1 3434502 R 595496 CDS YP_002928307.1 238902511 7952327 complement(3436596..3438989) 1 NC_012759.1 MG1655 equivalent: b3417; maltodextrin phosphorylase 3438989 malP 7952327 malP Escherichia coli BW2952 maltodextrin phosphorylase YP_002928307.1 3436596 R 595496 CDS YP_002928308.1 238902512 7954204 3439601..3442306 1 NC_012759.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3442306 malT 7954204 malT Escherichia coli BW2952 transcriptional regulator MalT YP_002928308.1 3439601 D 595496 CDS YP_002928309.1 238902513 7953667 complement(3442349..3443365) 1 NC_012759.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3443365 rtcA 7953667 rtcA Escherichia coli BW2952 RNA 3'-terminal-phosphate cyclase YP_002928309.1 3442349 R 595496 CDS YP_002928310.1 238902514 7955981 complement(3443369..3444595) 1 NC_012759.1 MG1655 equivalent: b3421; hypothetical protein 3444595 rtcB 7955981 rtcB Escherichia coli BW2952 hypothetical protein YP_002928310.1 3443369 R 595496 CDS YP_002928311.1 238902515 7952882 3444784..3446382 1 NC_012759.1 MG1655 equivalent: b3422; sigma 54-dependent transcriptional regulator of rtcBA expression 3446382 rtcR 7952882 rtcR Escherichia coli BW2952 sigma 54-dependent transcriptional regulator of rtcBA expression YP_002928311.1 3444784 D 595496 CDS YP_002928312.1 238902516 7956044 complement(3446364..3447122) 1 NC_012759.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3447122 glpR 7956044 glpR Escherichia coli BW2952 DNA-binding transcriptional repressor GlpR YP_002928312.1 3446364 R 595496 CDS YP_002928313.1 238902517 7953456 complement(3447139..3447969) 1 NC_012759.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3447969 glpG 7953456 glpG Escherichia coli BW2952 intramembrane serine protease GlpG YP_002928313.1 3447139 R 595496 CDS YP_002928314.1 238902518 7955084 complement(3448014..3448340) 1 NC_012759.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3448340 glpE 7955084 glpE Escherichia coli BW2952 thiosulfate sulfurtransferase YP_002928314.1 3448014 R 595496 CDS YP_002928315.1 238902519 7956138 3448530..3450035 1 NC_012759.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3450035 glpD 7956138 glpD Escherichia coli BW2952 glycerol-3-phosphate dehydrogenase YP_002928315.1 3448530 D 595496 CDS YP_002928316.1 238902520 7956053 complement(3450651..3453098) 1 NC_012759.1 MG1655 equivalent: b3428; glycogen phosphorylase 3453098 glgP 7956053 glgP Escherichia coli BW2952 glycogen phosphorylase YP_002928316.1 3450651 R 595496 CDS YP_002928317.1 238902521 7953864 complement(3453117..3454550) 1 NC_012759.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3454550 glgA 7953864 glgA Escherichia coli BW2952 glycogen synthase YP_002928317.1 3453117 R 595496 CDS YP_002928318.1 238902522 7953865 complement(3454550..3455845) 1 NC_012759.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3455845 glgC 7953865 glgC Escherichia coli BW2952 glucose-1-phosphate adenylyltransferase YP_002928318.1 3454550 R 595496 CDS YP_002928319.1 238902523 7953805 complement(3455863..3457836) 1 NC_012759.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 3457836 glgX 7953805 glgX Escherichia coli BW2952 glycogen debranching protein YP_002928319.1 3455863 R 595496 CDS YP_002928320.1 238902524 7953863 complement(3457833..3460019) 1 NC_012759.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3460019 glgB 7953863 glgB Escherichia coli BW2952 glycogen branching protein YP_002928320.1 3457833 R 595496 CDS YP_002928321.1 238902525 7952219 complement(3460292..3461395) 1 NC_012759.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3461395 asd 7952219 asd Escherichia coli BW2952 aspartate-semialdehyde dehydrogenase YP_002928321.1 3460292 R 595496 CDS YP_002928322.1 238902526 7952515 3461588..3462181 1 NC_012759.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 3462181 yhgN 7952515 yhgN Escherichia coli BW2952 putative dITP- and XTP- hydrolase YP_002928322.1 3461588 D 595496 CDS YP_002928323.1 238902527 7954648 complement(3462238..3463578) 1 NC_012759.1 MG1655 equivalent: b4476; low affinity gluconate transporter 3463578 gntU 7954648 gntU Escherichia coli BW2952 low affinity gluconate transporter YP_002928323.1 3462238 R 595496 CDS YP_002928324.1 238902528 7953800 complement(3463582..3464109) 1 NC_012759.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 3464109 gntK 7953800 gntK Escherichia coli BW2952 gluconate kinase YP_002928324.1 3463582 R 595496 CDS YP_002928325.1 238902529 7953797 complement(3464248..3465243) 1 NC_012759.1 MG1655 equivalent: b3438; DNA-binding transcriptional repressor 3465243 gntR 7953797 gntR Escherichia coli BW2952 DNA-binding transcriptional repressor YP_002928325.1 3464248 R 595496 CDS YP_002928326.1 238902530 7953457 complement(3465467..3466162) 1 NC_012759.1 MG1655 equivalent: b3439; hypothetical protein 3466162 yhhW 7953457 yhhW Escherichia coli BW2952 hypothetical protein YP_002928326.1 3465467 R 595496 CDS YP_002928327.1 238902531 7955421 complement(3466285..3467322) 1 NC_012759.1 MG1655 equivalent: b3440; putative dehydrogenase 3467322 yhhX 7955421 yhhX Escherichia coli BW2952 putative dehydrogenase YP_002928327.1 3466285 R 595496 CDS YP_002928328.1 238902532 7952096 3467655..3468143 1 NC_012759.1 YhhY; regulated by the fur regulator; unknown function; putative acetyltransferase YhhY 3468143 yhhY 7952096 yhhY Escherichia coli BW2952 putative acetyltransferase YhhY YP_002928328.1 3467655 D 595496 CDS YP_002928329.1 238902533 7954603 3468380..3469558 1 NC_012759.1 MG1655 equivalent: b3442; hypothetical protein 3469558 yhhZ 7954603 yhhZ Escherichia coli BW2952 hypothetical protein YP_002928329.1 3468380 D 595496 CDS YP_002928330.1 238902534 7953030 3470000..3470275 1 NC_012759.1 MG1655 equivalent: b3444; KpLE2 phage-like element; IS1 repressor protein InsA 3470275 insA 7953030 insA Escherichia coli BW2952 KpLE2 phage-like element; IS1 repressor protein InsA YP_002928330.1 3470000 D 595496 CDS YP_002928331.1 238902535 7954068 3470194..3470697 1 NC_012759.1 MG1655 equivalent: b3445; IS1 transposase InsAB' 3470697 insB 7954068 insB Escherichia coli BW2952 IS1 transposase InsAB' YP_002928331.1 3470194 D 595496 CDS YP_002928332.1 238902536 7954022 3470921..3471076 1 NC_012759.1 MG1655 equivalent: b4612; hypothetical protein 3471076 yrhD 7954022 yrhD Escherichia coli BW2952 hypothetical protein YP_002928332.1 3470921 D 595496 CDS YP_002928333.1 238902537 7953982 3471276..3471560 1 NC_012759.1 MG1655 equivalent: b3446; hypothetical protein 3471560 yrhB 7953982 yrhB Escherichia coli BW2952 hypothetical protein YP_002928333.1 3471276 D 595496 CDS YP_002928334.1 238902538 7955516 complement(3471598..3473340) 1 NC_012759.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3473340 ggt 7955516 ggt Escherichia coli BW2952 gamma-glutamyltranspeptidase YP_002928334.1 3471598 R 595496 CDS YP_002928335.1 238902539 7953772 3473460..3473900 1 NC_012759.1 MG1655 equivalent: b3448; hypothetical protein 3473900 yhhA 7953772 yhhA Escherichia coli BW2952 hypothetical protein YP_002928335.1 3473460 D 595496 CDS YP_002928336.1 238902540 7953031 complement(3473887..3474630) 1 NC_012759.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 3474630 ugpQ 7953031 ugpQ Escherichia coli BW2952 glycerophosphodiester phosphodiesterase YP_002928336.1 3473887 R 595496 CDS YP_002928337.1 238902541 7953854 complement(3474627..3475697) 1 NC_012759.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3475697 ugpC 7953854 ugpC Escherichia coli BW2952 glycerol-3-phosphate transporter ATP-binding subunit YP_002928337.1 3474627 R 595496 CDS YP_002928338.1 238902542 7953850 complement(3475699..3476544) 1 NC_012759.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3476544 ugpE 7953850 ugpE Escherichia coli BW2952 glycerol-3-phosphate transporter membrane protein YP_002928338.1 3475699 R 595496 CDS YP_002928339.1 238902543 7953851 complement(3476541..3477428) 1 NC_012759.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3477428 ugpA 7953851 ugpA Escherichia coli BW2952 glycerol-3-phosphate transporter permease YP_002928339.1 3476541 R 595496 CDS YP_002928340.1 238902544 7953852 complement(3477526..3478842) 1 NC_012759.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3478842 ugpB 7953852 ugpB Escherichia coli BW2952 glycerol-3-phosphate transporter periplasmic binding protein YP_002928340.1 3477526 R 595496 CDS YP_002928341.1 238902545 7953853 complement(3479241..3479954) 1 NC_012759.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3479954 livF 7953853 livF Escherichia coli BW2952 leucine/isoleucine/valine transporter ATP-binding subunit YP_002928341.1 3479241 R 595496 CDS YP_002928342.1 238902546 7954126 complement(3479956..3480723) 1 NC_012759.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3480723 livG 7954126 livG Escherichia coli BW2952 leucine/isoleucine/valine transporter ATP-binding subunit YP_002928342.1 3479956 R 595496 CDS YP_002928343.1 238902547 7954127 complement(3480720..3481997) 1 NC_012759.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3481997 livM 7954127 livM Escherichia coli BW2952 leucine/isoleucine/valine transporter permease subunit YP_002928343.1 3480720 R 595496 CDS YP_002928344.1 238902548 7954128 complement(3481994..3482920) 1 NC_012759.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3482920 livH 7954128 livH Escherichia coli BW2952 branched-chain amino acid transporter permease subunit LivH YP_002928344.1 3481994 R 595496 CDS YP_002928345.1 238902549 7954129 complement(3482968..3484077) 1 NC_012759.1 MG1655 equivalent: b3458; leucine transporter subunit 3484077 livK 7954129 livK Escherichia coli BW2952 leucine transporter subunit YP_002928345.1 3482968 R 595496 CDS YP_002928346.1 238902550 7954125 3484501..3484884 1 NC_012759.1 MG1655 equivalent: b3459; hypothetical protein 3484884 yhhK 7954125 yhhK Escherichia coli BW2952 hypothetical protein YP_002928346.1 3484501 D 595496 CDS YP_002928347.1 238902551 7953032 complement(3485072..3486175) 1 NC_012759.1 MG1655 equivalent: b3460; leucine/isoleucine/valine transporter subunit 3486175 livJ 7953032 livJ Escherichia coli BW2952 leucine/isoleucine/valine transporter subunit YP_002928347.1 3485072 R 595496 CDS YP_002928348.1 238902552 7954130 complement(3486446..3487300) 1 NC_012759.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3487300 rpoH 7954130 rpoH Escherichia coli BW2952 RNA polymerase factor sigma-32 YP_002928348.1 3486446 R 595496 CDS YP_002928349.1 238902553 7955989 complement(3487545..3488603) 1 NC_012759.1 putative ABC transporter, membrane protein; cell division protein FtsX 3488603 ftsX 7955989 ftsX Escherichia coli BW2952 cell division protein FtsX YP_002928349.1 3487545 R 595496 CDS YP_002928350.1 238902554 7955731 complement(3488596..3489264) 1 NC_012759.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3489264 ftsE 7955731 ftsE Escherichia coli BW2952 cell division protein FtsE YP_002928350.1 3488596 R 595496 CDS YP_002928351.1 238902555 7955719 complement(3489267..3490760) 1 NC_012759.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3490760 ftsY 7955719 ftsY Escherichia coli BW2952 cell division protein FtsY YP_002928351.1 3489267 R 595496 CDS YP_002928352.1 238902556 7953742 3490910..3491506 1 NC_012759.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3491506 rsmD 7953742 rsmD Escherichia coli BW2952 16S rRNA m(2)G966-methyltransferase YP_002928352.1 3490910 D 595496 CDS YP_002928353.1 238902557 7955161 3491496..3491765 1 NC_012759.1 MG1655 equivalent: b3466; hypothetical protein 3491765 yhhL 7955161 yhhL Escherichia coli BW2952 hypothetical protein YP_002928353.1 3491496 D 595496 CDS YP_002928354.1 238902558 7952725 complement(3491768..3492127) 1 NC_012759.1 MG1655 equivalent: b3467; hypothetical protein 3492127 yhhM 7952725 yhhM Escherichia coli BW2952 hypothetical protein YP_002928354.1 3491768 R 595496 CDS YP_002928355.1 238902559 7952883 3492268..3492894 1 NC_012759.1 MG1655 equivalent: b3468; hypothetical protein 3492894 yhhN 7952883 yhhN Escherichia coli BW2952 hypothetical protein YP_002928355.1 3492268 D 595496 CDS YP_002928356.1 238902560 7952726 3492968..3495166 1 NC_012759.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3495166 zntA 7952726 zntA Escherichia coli BW2952 zinc/cadmium/mercury/lead-transporting ATPase YP_002928356.1 3492968 D 595496 CDS YP_002928357.1 238902561 7956289 complement(3495268..3495513) 1 NC_012759.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 3495513 sirA 7956289 sirA Escherichia coli BW2952 sulfur transfer protein SirA YP_002928357.1 3495268 R 595496 CDS YP_002928358.1 238902562 7953076 3495734..3496399 1 NC_012759.1 MG1655 equivalent: b3471; hypothetical protein 3496399 yhhQ 7953076 yhhQ Escherichia coli BW2952 hypothetical protein YP_002928358.1 3495734 D 595496 CDS YP_002928359.1 238902563 7952727 3496472..3497029 1 NC_012759.1 MG1655 equivalent: b3472; hypothetical protein 3497029 dcrB 7952727 dcrB Escherichia coli BW2952 hypothetical protein YP_002928359.1 3496472 D 595496 CDS YP_002928360.1 238902564 7954496 complement(3497033..3498250) 1 NC_012759.1 MG1655 equivalent: b3473; major facilitator superfamily transporter 3498250 yhhS 7954496 yhhS Escherichia coli BW2952 major facilitator superfamily transporter YP_002928360.1 3497033 R 595496 CDS YP_002928361.1 238902565 7955666 3498382..3499431 1 NC_012759.1 MG1655 equivalent: b3474; putative inner membrane protein 3499431 yhhT 7955666 yhhT Escherichia coli BW2952 putative inner membrane protein YP_002928361.1 3498382 D 595496 CDS YP_002928362.1 238902566 7955067 3499486..3500073 1 NC_012759.1 MG1655 equivalent: b3475; holo-(acyl carrier protein) synthase 2 3500073 acpT 7955067 acpT Escherichia coli BW2952 holo-(acyl carrier protein) synthase 2 YP_002928362.1 3499486 D 595496 CDS YP_002928363.1 238902567 7953916 3500184..3501758 1 NC_012759.1 MG1655 equivalent: b3476; nickel transporter subunit 3501758 nikA 7953916 nikA Escherichia coli BW2952 nickel transporter subunit YP_002928363.1 3500184 D 595496 CDS YP_002928364.1 238902568 7954377 3501758..3502702 1 NC_012759.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3502702 nikB 7954377 nikB Escherichia coli BW2952 nickel transporter permease NikB YP_002928364.1 3501758 D 595496 CDS YP_002928365.1 238902569 7954378 3502699..3503532 1 NC_012759.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3503532 nikC 7954378 nikC Escherichia coli BW2952 nickel transporter permease NikC YP_002928365.1 3502699 D 595496 CDS YP_002928366.1 238902570 7954379 3503532..3504296 1 NC_012759.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3504296 nikD 7954379 nikD Escherichia coli BW2952 nickel transporter ATP-binding protein NikD YP_002928366.1 3503532 D 595496 CDS YP_002928367.1 238902571 7954380 3504293..3505099 1 NC_012759.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3505099 nikE 7954380 nikE Escherichia coli BW2952 nickel transporter ATP-binding protein NikE YP_002928367.1 3504293 D 595496 CDS YP_002928368.1 238902572 7954381 3505105..3505506 1 NC_012759.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3505506 nikR 7954381 nikR Escherichia coli BW2952 nickel responsive regulator YP_002928368.1 3505105 D 595496 CDS YP_002928369.1 238902573 7953479 3505709..3509944 1 NC_012759.1 MG1655 equivalent: b3482; rhsB element core protein RshB 3509944 rhsB 7953479 rhsB Escherichia coli BW2952 rhsB element core protein RshB YP_002928369.1 3505709 D 595496 CDS YP_002928370.1 238902574 7955950 3509916..3510299 1 NC_012759.1 MG1655 equivalent: b3483; hypothetical protein 3510299 yhhH 7955950 yhhH Escherichia coli BW2952 hypothetical protein YP_002928370.1 3509916 D 595496 CDS YP_002928371.1 238902575 7955517 3510895..3512031 1 NC_012759.1 MG1655 equivalent: b3484; putative transposase 3512031 yhhI 7955517 yhhI Escherichia coli BW2952 putative transposase YP_002928371.1 3510895 D 595496 CDS YP_002928372.1 238902576 7955742 complement(3512196..3513323) 1 NC_012759.1 MG1655 equivalent: b3485; putative transporter subunit: membrane component of ABC superfamily 3513323 yhhJ 7955742 yhhJ Escherichia coli BW2952 putative transporter subunit: membrane component of ABC superfamily YP_002928372.1 3512196 R 595496 CDS YP_002928373.1 238902577 7955732 complement(3513320..3516055) 1 NC_012759.1 MG1655 equivalent: b3486; fused ribosome-associated ATPase: ATP-binding protein/ATP-binding protein/putative membrane protein 3516055 rbbA 7955732 rbbA Escherichia coli BW2952 fused ribosome-associated ATPase: ATP-binding protein/ATP-binding protein/putative membrane protein YP_002928373.1 3513320 R 595496 CDS YP_002928374.1 238902578 7953740 complement(3516052..3517119) 1 NC_012759.1 MG1655 equivalent: b3487; putative HlyD family secretion protein 3517119 yhiI 7953740 yhiI Escherichia coli BW2952 putative HlyD family secretion protein YP_002928374.1 3516052 R 595496 CDS YP_002928375.1 238902579 7954945 complement(3517485..3519107) 1 NC_012759.1 MG1655 equivalent: b3488; hypothetical protein 3519107 yhiJ 7954945 yhiJ Escherichia coli BW2952 hypothetical protein YP_002928375.1 3517485 R 595496 CDS YP_002928376.1 238902580 7955422 3521316..3522410 1 NC_012759.1 MG1655 equivalent: b3491; hypothetical protein 3522410 yhiM 7955422 yhiM Escherichia coli BW2952 hypothetical protein YP_002928376.1 3521316 D 595496 CDS YP_002928377.1 238902581 7952728 complement(3522725..3523927) 1 NC_012759.1 MG1655 equivalent: b3492; putative oxidoreductase with FAD/NAD(P)-binding domain 3523927 yhiN 7952728 yhiN Escherichia coli BW2952 putative oxidoreductase with FAD/NAD(P)-binding domain YP_002928377.1 3522725 R 595496 CDS YP_002928378.1 238902582 7955240 3524159..3525658 1 NC_012759.1 MG1655 equivalent: b3493; phosphate transporter, low-affinity 3525658 pitA 7955240 pitA Escherichia coli BW2952 phosphate transporter, low-affinity YP_002928378.1 3524159 D 595496 CDS YP_002928379.1 238902583 7954519 complement(3525902..3526237) 1 NC_012759.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3526237 uspB 7954519 uspB Escherichia coli BW2952 universal stress protein UspB YP_002928379.1 3525902 R 595496 CDS YP_002928380.1 238902584 7955746 3526628..3527062 1 NC_012759.1 MG1655 equivalent: b3495; universal stress global response regulator 3527062 uspA 7955746 uspA Escherichia coli BW2952 universal stress global response regulator YP_002928380.1 3526628 D 595496 CDS YP_002928381.1 238902585 7956253 3527379..3528848 1 NC_012759.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3528848 yhiP 7956253 yhiP Escherichia coli BW2952 inner membrane transporter YhiP YP_002928381.1 3527379 D 595496 CDS YP_002928382.1 238902586 7955705 complement(3528897..3529649) 1 NC_012759.1 predicted SAM-dependent methyltransferase; putative methyltransferase 3529649 yhiQ 7955705 yhiQ Escherichia coli BW2952 putative methyltransferase YP_002928382.1 3528897 R 595496 CDS YP_002928383.1 238902587 7955582 complement(3529657..3531699) 1 NC_012759.1 MG1655 equivalent: b3498; oligopeptidase A 3531699 prlC 7955582 prlC Escherichia coli BW2952 oligopeptidase A YP_002928383.1 3529657 R 595496 CDS YP_002928384.1 238902588 7954421 3531902..3532744 1 NC_012759.1 MG1655 equivalent: b3499; putative DNA processing protein 3532744 yhiR 7954421 yhiR Escherichia coli BW2952 putative DNA processing protein YP_002928384.1 3531902 D 595496 CDS YP_002928385.1 238902589 7954736 3532816..3534168 1 NC_012759.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3534168 gor 7954736 gor Escherichia coli BW2952 glutathione reductase YP_002928385.1 3532816 D 595496 CDS YP_002928386.1 238902590 7953839 complement(3534222..3534350) 1 NC_012759.1 MG1655 equivalent: b4613; Damage inducible protein 3534350 dinQ 7953839 dinQ Escherichia coli BW2952 Damage inducible protein YP_002928386.1 3534222 R 595496 CDS YP_002928387.1 238902591 7953225 3535045..3535398 1 NC_012759.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3535398 arsR 7953225 arsR Escherichia coli BW2952 DNA-binding transcriptional repressor ArsR YP_002928387.1 3535045 D 595496 CDS YP_002928388.1 238902592 7953468 3535452..3536741 1 NC_012759.1 MG1655 equivalent: b3502; arsenite/antimonite transporter 3536741 arsB 7953468 arsB Escherichia coli BW2952 arsenite/antimonite transporter YP_002928388.1 3535452 D 595496 CDS YP_002928389.1 238902593 7952506 3536754..3537179 1 NC_012759.1 MG1655 equivalent: b3503; arsenate reductase 3537179 arsC 7952506 arsC Escherichia coli BW2952 arsenate reductase YP_002928389.1 3536754 D 595496 CDS YP_002928390.1 238902594 7952505 complement(3538699..3539715) 1 NC_012759.1 MG1655 equivalent: b3505; IS5 transposase and trans-activator 3539715 insH 7952505 insH Escherichia coli BW2952 IS5 transposase and trans-activator YP_002928390.1 3538699 R 595496 CDS YP_002928391.1 238902595 7954044 3540478..3541044 1 NC_012759.1 MG1655 equivalent: b3506; outer membrane lipoprotein 3541044 slp 7954044 slp Escherichia coli BW2952 outer membrane lipoprotein YP_002928391.1 3540478 D 595496 CDS YP_002928392.1 238902596 7954439 3541200..3541730 1 NC_012759.1 MG1655 equivalent: b3507; putative DNA-binding ranscriptional regulator 3541730 dctR 7954439 dctR Escherichia coli BW2952 putative DNA-binding ranscriptional regulator YP_002928392.1 3541200 D 595496 CDS YP_002928393.1 238902597 7954739 complement(3541772..3542419) 1 NC_012759.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase 3542419 yhiD 7954739 yhiD Escherichia coli BW2952 putative Mg(2+) transport ATPase YP_002928393.1 3541772 R 595496 CDS YP_002928394.1 238902598 7955163 complement(3542483..3542809) 1 NC_012759.1 MG1655 equivalent: b3509; acid-resistance protein 3542809 hdeB 7955163 hdeB Escherichia coli BW2952 acid-resistance protein YP_002928394.1 3542483 R 595496 CDS YP_002928395.1 238902599 7952410 complement(3542925..3543257) 1 NC_012759.1 inactive form; acid-resistance protein 3543257 hdeA 7952410 hdeA Escherichia coli BW2952 acid-resistance protein YP_002928395.1 3542925 R 595496 CDS YP_002928396.1 238902600 7956071 3543512..3544084 1 NC_012759.1 MG1655 equivalent: b3511; acid-resistance membrane protein 3544084 hdeD 7956071 hdeD Escherichia coli BW2952 acid-resistance membrane protein YP_002928396.1 3543512 D 595496 CDS YP_002928397.1 238902601 7952409 3544883..3545410 1 NC_012759.1 MG1655 equivalent: b3512; DNA-binding transcriptional activator 3545410 gadE 7952409 gadE Escherichia coli BW2952 DNA-binding transcriptional activator YP_002928397.1 3544883 D 595496 CDS YP_002928398.1 238902602 7953383 3545749..3546906 1 NC_012759.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3546906 mdtE 7953383 mdtE Escherichia coli BW2952 multidrug efflux system protein MdtE YP_002928398.1 3545749 D 595496 CDS YP_002928399.1 238902603 7954314 3546931..3550044 1 NC_012759.1 MG1655 equivalent: b3514; multidrug transporter, RpoS-dependent 3550044 mdtF 7954314 mdtF Escherichia coli BW2952 multidrug transporter, RpoS-dependent YP_002928399.1 3546931 D 595496 CDS YP_002928400.1 238902604 7954315 complement(3550407..3551135) 1 NC_012759.1 MG1655 equivalent: b3515; DNA-binding transcriptional activator 3551135 gadW 7954315 gadW Escherichia coli BW2952 DNA-binding transcriptional activator YP_002928400.1 3550407 R 595496 CDS YP_002928401.1 238902605 7952196 complement(3551503..3552327) 1 NC_012759.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3552327 gadX 7952196 gadX Escherichia coli BW2952 DNA-binding transcriptional regulator GadX YP_002928401.1 3551503 R 595496 CDS YP_002928402.1 238902606 7953411 complement(3552697..3554097) 1 NC_012759.1 MG1655 equivalent: b3517; glutamate decarboxylase 3554097 gadA 7953411 gadA Escherichia coli BW2952 glutamate decarboxylase YP_002928402.1 3552697 R 595496 CDS YP_002928403.1 238902607 7953818 complement(3554308..3555705) 1 NC_012759.1 MG1655 equivalent: b3518; putative cytochrome C peroxidase 3555705 yhjA 7953818 yhjA Escherichia coli BW2952 putative cytochrome C peroxidase YP_002928403.1 3554308 R 595496 CDS YP_002928404.1 238902608 7954709 3556109..3557758 1 NC_012759.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3557758 treF 7954709 treF Escherichia coli BW2952 trehalase YP_002928404.1 3556109 D 595496 CDS YP_002928405.1 238902609 7953205 complement(3557809..3558411) 1 NC_012759.1 MG1655 equivalent: b3520; putative DNA-binding response regulator in two-component regulatory system 3558411 yhjB 7953205 yhjB Escherichia coli BW2952 putative DNA-binding response regulator in two-component regulatory system YP_002928405.1 3557809 R 595496 CDS YP_002928406.1 238902610 7954740 3558931..3559830 1 NC_012759.1 MG1655 equivalent: b3521; putative DNA-binding transcriptional regulator 3559830 yhjC 7954740 yhjC Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928406.1 3558931 D 595496 CDS YP_002928407.1 238902611 7954811 3559879..3560892 1 NC_012759.1 MG1655 equivalent: b3522; hypothetical protein 3560892 yhjD 7954811 yhjD Escherichia coli BW2952 hypothetical protein YP_002928407.1 3559879 D 595496 CDS YP_002928408.1 238902612 7952729 3561303..3562625 1 NC_012759.1 MG1655 equivalent: b3523; putative transporter 3562625 yhjE 7952729 yhjE Escherichia coli BW2952 putative transporter YP_002928408.1 3561303 D 595496 CDS YP_002928409.1 238902613 7955706 complement(3562807..3564882) 1 NC_012759.1 MG1655 equivalent: b3524; putative outer membrane biogenesis protein 3564882 yhjG 7955706 yhjG Escherichia coli BW2952 putative outer membrane biogenesis protein YP_002928409.1 3562807 R 595496 CDS YP_002928410.1 238902614 7955195 complement(3564937..3565704) 1 NC_012759.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 3565704 yhjH 7955195 yhjH Escherichia coli BW2952 EAL domain-containing protein YP_002928410.1 3564937 R 595496 CDS YP_002928411.1 238902615 7953512 3565936..3566865 1 NC_012759.1 MG1655 equivalent: b3526; ketodeoxygluconokinase 3566865 kdgK 7953512 kdgK Escherichia coli BW2952 ketodeoxygluconokinase YP_002928411.1 3565936 D 595496 CDS YP_002928412.1 238902616 7954059 complement(3566961..3568457) 1 NC_012759.1 MG1655 equivalent: b3527; putative zinc-dependent peptidase 3568457 yhjJ 7954059 yhjJ Escherichia coli BW2952 putative zinc-dependent peptidase YP_002928412.1 3566961 R 595496 CDS YP_002928413.1 238902617 7955755 complement(3568678..3569964) 1 NC_012759.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 3569964 dctA 7955755 dctA Escherichia coli BW2952 C4-dicarboxylate transporter DctA YP_002928413.1 3568678 R 595496 CDS YP_002928414.1 238902618 7952588 complement(3570147..3572102) 1 NC_012759.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase 3572102 yhjK 7952588 yhjK Escherichia coli BW2952 putative phosphodiesterase YP_002928414.1 3570147 R 595496 CDS YP_002928415.1 238902619 7954725 complement(3572217..3575639) 1 NC_012759.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 3575639 bcsC 7954725 bcsC Escherichia coli BW2952 cellulose synthase subunit BcsC YP_002928415.1 3572217 R 595496 CDS YP_002928416.1 238902620 7952623 complement(3575672..3576778) 1 NC_012759.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 3576778 bcsZ 7952623 bcsZ Escherichia coli BW2952 endo-1,4-D-glucanase YP_002928416.1 3575672 R 595496 CDS YP_002928417.1 238902621 7953516 complement(3576785..3579124) 1 NC_012759.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 3579124 bcsB 7953516 bcsB Escherichia coli BW2952 cellulose synthase regulator protein YP_002928417.1 3576785 R 595496 CDS YP_002928418.1 238902622 7955919 complement(3579135..3581753) 1 NC_012759.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 3581753 bcsA 7955919 bcsA Escherichia coli BW2952 cellulose synthase catalytic subunit YP_002928418.1 3579135 R 595496 CDS YP_002928419.1 238902623 7952624 complement(3582514..3582702) 1 NC_012759.1 MG1655 equivalent: b3535; hypothetical protein 3582702 yhjR 7952624 yhjR Escherichia coli BW2952 hypothetical protein YP_002928419.1 3582514 R 595496 CDS YP_002928420.1 238902624 7952884 3582975..3584546 1 NC_012759.1 MG1655 equivalent: b3536; hypothetical protein 3584546 bcsE 7952884 bcsE Escherichia coli BW2952 hypothetical protein YP_002928420.1 3582975 D 595496 CDS YP_002928421.1 238902625 7953033 3584543..3584734 1 NC_012759.1 MG1655 equivalent: b3537; hypothetical protein 3584734 bcsF 7953033 bcsF Escherichia coli BW2952 hypothetical protein YP_002928421.1 3584543 D 595496 CDS YP_002928422.1 238902626 7955518 3584731..3586410 1 NC_012759.1 MG1655 equivalent: b3538; putative inner membrane protein 3586410 bcsG 7955518 bcsG Escherichia coli BW2952 putative inner membrane protein YP_002928422.1 3584731 D 595496 CDS YP_002928423.1 238902627 7955068 complement(3586497..3586604) 1 NC_012759.1 MG1655 equivalent: b4453; toxic polypeptide, small 3586604 ldrD 7955068 ldrD Escherichia coli BW2952 toxic polypeptide, small YP_002928423.1 3586497 R 595496 CDS YP_002928424.1 238902628 7952197 3587080..3588351 1 NC_012759.1 MG1655 equivalent: b3539; putative transporter 3588351 yhjV 7952197 yhjV Escherichia coli BW2952 putative transporter YP_002928424.1 3587080 D 595496 CDS YP_002928425.1 238902629 7955707 complement(3588381..3589385) 1 NC_012759.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 3589385 dppF 7955707 dppF Escherichia coli BW2952 dipeptide transporter ATP-binding subunit YP_002928425.1 3588381 R 595496 CDS YP_002928426.1 238902630 7953264 complement(3589382..3590365) 1 NC_012759.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 3590365 dppD 7953264 dppD Escherichia coli BW2952 dipeptide transporter ATP-binding subunit YP_002928426.1 3589382 R 595496 CDS YP_002928427.1 238902631 7953265 complement(3590376..3591278) 1 NC_012759.1 MG1655 equivalent: b3542; dipeptide transporter 3591278 dppC 7953265 dppC Escherichia coli BW2952 dipeptide transporter YP_002928427.1 3590376 R 595496 CDS YP_002928428.1 238902632 7953266 complement(3591288..3592307) 1 NC_012759.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 3592307 dppB 7953266 dppB Escherichia coli BW2952 dipeptide transporter permease DppB YP_002928428.1 3591288 R 595496 CDS YP_002928429.1 238902633 7953267 complement(3592615..3594222) 1 NC_012759.1 MG1655 equivalent: b3544; dipeptide transporter 3594222 dppA 7953267 dppA Escherichia coli BW2952 dipeptide transporter YP_002928429.1 3592615 R 595496 CDS YP_002928430.1 238902634 7952073 complement(3595133..3596824) 1 NC_012759.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 3596824 eptB 7952073 eptB Escherichia coli BW2952 phosphoethanolamine transferase YP_002928430.1 3595133 R 595496 CDS YP_002928431.1 238902635 7955143 complement(3597148..3598356) 1 NC_012759.1 MG1655 equivalent: b3547; putative transporter 3598356 yhjX 7955143 yhjX Escherichia coli BW2952 putative transporter YP_002928431.1 3597148 R 595496 CDS YP_002928432.1 238902636 7955667 complement(3598585..3599283) 1 NC_012759.1 MG1655 equivalent: b3548; hypothetical protein 3599283 yhjY 7955667 yhjY Escherichia coli BW2952 hypothetical protein YP_002928432.1 3598585 R 595496 CDS YP_002928433.1 238902637 7952885 3599441..3600004 1 NC_012759.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3600004 tag 7952885 tag Escherichia coli BW2952 3-methyladenine DNA glycosylase YP_002928433.1 3599441 D 595496 CDS YP_002928434.1 238902638 7952313 3600001..3600441 1 NC_012759.1 MG1655 equivalent: b3550; hypothetical protein 3600441 yiaC 7952313 yiaC Escherichia coli BW2952 hypothetical protein YP_002928434.1 3600001 D 595496 CDS YP_002928435.1 238902639 7954621 complement(3600410..3602743) 1 NC_012759.1 MG1655 equivalent: b3551; biotin sulfoxide reductase 3602743 bisC 7954621 bisC Escherichia coli BW2952 biotin sulfoxide reductase YP_002928435.1 3600410 R 595496 CDS YP_002928436.1 238902640 7952581 3602896..3603555 1 NC_012759.1 MG1655 equivalent: b3552; putative outer membrane lipoprotein 3603555 yiaD 7952581 yiaD Escherichia coli BW2952 putative outer membrane lipoprotein YP_002928436.1 3602896 D 595496 CDS YP_002928437.1 238902641 7955205 3603659..3604633 1 NC_012759.1 MG1655 equivalent: b3553; 2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase) 3604633 ghrB 7955205 ghrB Escherichia coli BW2952 2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase) YP_002928437.1 3603659 D 595496 CDS YP_002928438.1 238902642 7952263 complement(3604683..3605393) 1 NC_012759.1 MG1655 equivalent: b3554; hypothetical protein 3605393 yiaF 7952263 yiaF Escherichia coli BW2952 hypothetical protein YP_002928438.1 3604683 R 595496 CDS YP_002928439.1 238902643 7952886 3605827..3606117 1 NC_012759.1 MG1655 equivalent: b3555; putative transcriptional regulator 3606117 yiaG 7952886 yiaG Escherichia coli BW2952 putative transcriptional regulator YP_002928439.1 3605827 D 595496 CDS YP_002928440.1 238902644 7955638 3606398..3606610 1 NC_012759.1 MG1655 equivalent: b3556; major cold shock protein 3606610 cspA 7955638 cspA Escherichia coli BW2952 major cold shock protein YP_002928440.1 3606398 D 595496 CDS YP_002928441.1 238902645 7954193 complement(3606797..3606949) 1 NC_012759.1 MG1655 equivalent: b4455; small toxic polypeptide 3606949 hokA 7954193 hokA Escherichia coli BW2952 small toxic polypeptide YP_002928441.1 3606797 R 595496 CDS YP_002928442.1 238902646 7956158 3607029..3607550 1 NC_012759.1 MG1655 equivalent: b3557; IS150 protein InsA 3607550 insJ 7956158 insJ Escherichia coli BW2952 IS150 protein InsA YP_002928442.1 3607029 D 595496 CDS YP_002928443.1 238902647 7954024 3607547..3608398 1 NC_012759.1 MG1655 equivalent: b3558; transposase IS150 3608398 insK 7954024 insK Escherichia coli BW2952 transposase IS150 YP_002928443.1 3607547 D 595496 CDS YP_002928444.1 238902648 7952205 complement(3608677..3610746) 1 NC_012759.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 3610746 glyS 7952205 glyS Escherichia coli BW2952 glycyl-tRNA synthetase subunit beta YP_002928444.1 3608677 R 595496 CDS YP_002928445.1 238902649 7953862 complement(3610756..3611667) 1 NC_012759.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 3611667 glyQ 7953862 glyQ Escherichia coli BW2952 glycyl-tRNA synthetase subunit alpha YP_002928445.1 3610756 R 595496 CDS YP_002928446.1 238902650 7953861 complement(3611762..3612061) 1 NC_012759.1 MG1655 equivalent: b4553; hypothetical protein 3612061 ysaB 7953861 ysaB Escherichia coli BW2952 hypothetical protein YP_002928446.1 3611762 R 595496 CDS YP_002928447.1 238902651 7955436 3612236..3613231 1 NC_012759.1 MG1655 equivalent: b3561; hypothetical protein 3613231 wecH 7955436 wecH Escherichia coli BW2952 hypothetical protein YP_002928447.1 3612236 D 595496 CDS YP_002928448.1 238902652 7952730 complement(3613273..3613710) 1 NC_012759.1 MG1655 equivalent: b3562; hypothetical protein 3613710 yiaA 7952730 yiaA Escherichia coli BW2952 hypothetical protein YP_002928448.1 3613273 R 595496 CDS YP_002928449.1 238902653 7952687 complement(3613756..3614097) 1 NC_012759.1 MG1655 equivalent: b3563; hypothetical protein 3614097 yiaB 7952687 yiaB Escherichia coli BW2952 hypothetical protein YP_002928449.1 3613756 R 595496 CDS YP_002928450.1 238902654 7952688 complement(3614266..3615720) 1 NC_012759.1 MG1655 equivalent: b3564; xylulokinase 3615720 xylB 7952688 xylB Escherichia coli BW2952 xylulokinase YP_002928450.1 3614266 R 595496 CDS YP_002928451.1 238902655 7956281 complement(3615792..3617114) 1 NC_012759.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 3617114 xylA 7956281 xylA Escherichia coli BW2952 xylose isomerase YP_002928451.1 3615792 R 595496 CDS YP_002928452.1 238902656 7953507 3617480..3618472 1 NC_012759.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3618472 xylF 7953507 xylF Escherichia coli BW2952 D-xylose transporter subunit XylF YP_002928452.1 3617480 D 595496 CDS YP_002928453.1 238902657 7953509 3618550..3620091 1 NC_012759.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3620091 xylG 7953509 xylG Escherichia coli BW2952 xylose transporter ATP-binding subunit YP_002928453.1 3618550 D 595496 CDS YP_002928454.1 238902658 7953678 3620069..3621250 1 NC_012759.1 MG1655 equivalent: b3568; D-xylose transporter subunit 3621250 xylH 7953678 xylH Escherichia coli BW2952 D-xylose transporter subunit YP_002928454.1 3620069 D 595496 CDS YP_002928455.1 238902659 7953510 3621328..3622506 1 NC_012759.1 MG1655 equivalent: b3569; DNA-binding transcriptional activator, xylose-binding 3622506 xylR 7953510 xylR Escherichia coli BW2952 DNA-binding transcriptional activator, xylose-binding YP_002928455.1 3621328 D 595496 CDS YP_002928456.1 238902660 7953401 complement(3622702..3623526) 1 NC_012759.1 MG1655 equivalent: b3570; hypothetical protein 3623526 bax 7953401 bax Escherichia coli BW2952 hypothetical protein YP_002928456.1 3622702 R 595496 CDS YP_002928457.1 238902661 7952887 3623846..3625876 1 NC_012759.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3625876 malS 7952887 malS Escherichia coli BW2952 periplasmic alpha-amylase YP_002928457.1 3623846 D 595496 CDS YP_002928458.1 238902662 7952455 3626054..3627307 1 NC_012759.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3627307 avtA 7952455 avtA Escherichia coli BW2952 valine--pyruvate transaminase YP_002928458.1 3626054 D 595496 CDS YP_002928459.1 238902663 7956269 complement(3627458..3627931) 1 NC_012759.1 MG1655 equivalent: b3573; putative hydrogenase, 4Fe-4S ferredoxin-type component 3627931 ysaA 7956269 ysaA Escherichia coli BW2952 putative hydrogenase, 4Fe-4S ferredoxin-type component YP_002928459.1 3627458 R 595496 CDS YP_002928460.1 238902664 7954949 complement(3628033..3628881) 1 NC_012759.1 MG1655 equivalent: b3574; putative DNA-binding transcriptional repressor 3628881 yiaJ 7954949 yiaJ Escherichia coli BW2952 putative DNA-binding transcriptional repressor YP_002928460.1 3628033 R 595496 CDS YP_002928461.1 238902665 7954824 3629082..3630080 1 NC_012759.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3630080 yiaK 7954824 yiaK Escherichia coli BW2952 2,3-diketo-L-gulonate reductase YP_002928461.1 3629082 D 595496 CDS YP_002928462.1 238902666 7952236 3630092..3630559 1 NC_012759.1 MG1655 equivalent: b3576; hypothetical protein 3630559 yiaL 7952236 yiaL Escherichia coli BW2952 hypothetical protein YP_002928462.1 3630092 D 595496 CDS YP_002928463.1 238902667 7953034 3630677..3631150 1 NC_012759.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease 3631150 yiaM 7953034 yiaM Escherichia coli BW2952 2,3-diketo-L-gulonate TRAP transporter small permease YP_002928463.1 3630677 D 595496 CDS YP_002928464.1 238902668 7955708 3631153..3632430 1 NC_012759.1 MG1655 equivalent: b3578; putative transporter 3632430 yiaN 7955708 yiaN Escherichia coli BW2952 putative transporter YP_002928464.1 3631153 D 595496 CDS YP_002928465.1 238902669 7955709 3632443..3633429 1 NC_012759.1 MG1655 equivalent: b3579; putative transporter 3633429 yiaO 7955709 yiaO Escherichia coli BW2952 putative transporter YP_002928465.1 3632443 D 595496 CDS YP_002928466.1 238902670 7955710 3633433..3634929 1 NC_012759.1 MG1655 equivalent: b3580; L-xylulose kinase 3634929 lyx 7955710 lyx Escherichia coli BW2952 L-xylulose kinase YP_002928466.1 3633433 D 595496 CDS YP_002928467.1 238902671 7954178 3634926..3635588 1 NC_012759.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3635588 sgbH 7954178 sgbH Escherichia coli BW2952 3-keto-L-gulonate-6-phosphate decarboxylase YP_002928467.1 3634926 D 595496 CDS YP_002928468.1 238902672 7952309 3635581..3636441 1 NC_012759.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 3636441 sgbU 7952309 sgbU Escherichia coli BW2952 putative L-xylulose 5-phosphate 3-epimerase YP_002928468.1 3635581 D 595496 CDS YP_002928469.1 238902673 7955125 3636435..3637130 1 NC_012759.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3637130 sgbE 7955125 sgbE Escherichia coli BW2952 L-ribulose-5-phosphate 4-epimerase YP_002928469.1 3636435 D 595496 CDS YP_002928470.1 238902674 7954169 complement(3637477..3638217) 1 NC_012759.1 MG1655 equivalent: b3584; hypothetical protein 3638217 yiaT 7954169 yiaT Escherichia coli BW2952 hypothetical protein YP_002928470.1 3637477 R 595496 CDS YP_002928471.1 238902675 7955423 3638341..3639315 1 NC_012759.1 MG1655 equivalent: b3585; putative DNA-binding transcriptional regulator 3639315 yiaU 7955423 yiaU Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928471.1 3638341 D 595496 CDS YP_002928472.1 238902676 7954812 complement(3639312..3640448) 1 NC_012759.1 MG1655 equivalent: b3586; membrane fusion protein (MFP) component of efflux pump, signal anchor 3640448 yiaV 7954812 yiaV Escherichia coli BW2952 membrane fusion protein (MFP) component of efflux pump, signal anchor YP_002928472.1 3639312 R 595496 CDS YP_002928473.1 238902677 7954227 complement(3640454..3640777) 1 NC_012759.1 MG1655 equivalent: b3587; hypothetical protein 3640777 yiaW 7954227 yiaW Escherichia coli BW2952 hypothetical protein YP_002928473.1 3640454 R 595496 CDS YP_002928474.1 238902678 7952689 complement(3641322..3642860) 1 NC_012759.1 MG1655 equivalent: b3588; aldehyde dehydrogenase B 3642860 aldB 7952689 aldB Escherichia coli BW2952 aldehyde dehydrogenase B YP_002928474.1 3641322 R 595496 CDS YP_002928475.1 238902679 7952444 complement(3643025..3644176) 1 NC_012759.1 MG1655 equivalent: b3589; putative alcohol dehydrogenase 3644176 yiaY 7952444 yiaY Escherichia coli BW2952 putative alcohol dehydrogenase YP_002928475.1 3643025 R 595496 CDS YP_002928476.1 238902680 7954869 complement(3644366..3646210) 1 NC_012759.1 MG1655 equivalent: b3590; selenocysteinyl-tRNA-specific translation factor 3646210 selB 7954869 selB Escherichia coli BW2952 selenocysteinyl-tRNA-specific translation factor YP_002928476.1 3644366 R 595496 CDS YP_002928477.1 238902681 7956008 complement(3646207..3647598) 1 NC_012759.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 3647598 selA 7956008 selA Escherichia coli BW2952 selenocysteine synthase YP_002928477.1 3646207 R 595496 CDS YP_002928478.1 238902682 7956007 complement(3647696..3648304) 1 NC_012759.1 MG1655 equivalent: b3592; putative glutathione S-transferase 3648304 yibF 7956007 yibF Escherichia coli BW2952 putative glutathione S-transferase YP_002928478.1 3647696 R 595496 CDS YP_002928479.1 238902683 7954927 3648532..3652665 1 NC_012759.1 MG1655 equivalent: b3593; rhsA element core protein RshA 3652665 rhsA 7954927 rhsA Escherichia coli BW2952 rhsA element core protein RshA YP_002928479.1 3648532 D 595496 CDS YP_002928480.1 238902684 7955949 3652686..3653528 1 NC_012759.1 MG1655 equivalent: b3594; hypothetical protein 3653528 yibA 7955949 yibA Escherichia coli BW2952 hypothetical protein YP_002928480.1 3652686 D 595496 CDS YP_002928481.1 238902685 7954179 3654526..3654987 1 NC_012759.1 MG1655 equivalent: b3596; hypothetical protein 3654987 yibG 7954179 yibG Escherichia coli BW2952 hypothetical protein YP_002928481.1 3654526 D 595496 CDS YP_002928482.1 238902686 7953035 3655694..3656029 1 NC_012759.1 MG1655 equivalent: b4615; hypothetical protein 3656029 yibV 7953035 yibV Escherichia coli BW2952 hypothetical protein YP_002928482.1 3655694 D 595496 CDS YP_002928483.1 238902687 7953986 complement(3656592..3657728) 1 NC_012759.1 MG1655 equivalent: b3597; hypothetical protein 3657728 yibH 7953986 yibH Escherichia coli BW2952 hypothetical protein YP_002928483.1 3656592 R 595496 CDS YP_002928484.1 238902688 7955424 complement(3657731..3658093) 1 NC_012759.1 MG1655 equivalent: b3598; putative inner membrane protein 3658093 yibI 7955424 yibI Escherichia coli BW2952 putative inner membrane protein YP_002928484.1 3657731 R 595496 CDS YP_002928485.1 238902689 7955012 3658630..3660543 1 NC_012759.1 MG1655 equivalent: b3599; fused mannitol-specific PTS enzymes: IIA components/IIB components/IIC components 3660543 mtlA 7955012 mtlA Escherichia coli BW2952 fused mannitol-specific PTS enzymes: IIA components/IIB components/IIC components YP_002928485.1 3658630 D 595496 CDS YP_002928486.1 238902690 7953698 3660773..3661921 1 NC_012759.1 MG1655 equivalent: b3600; mannitol-1-phosphate 5-dehydrogenase 3661921 mtlD 7953698 mtlD Escherichia coli BW2952 mannitol-1-phosphate 5-dehydrogenase YP_002928486.1 3660773 D 595496 CDS YP_002928487.1 238902691 7954211 3661921..3662508 1 NC_012759.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 3662508 mtlR 7954211 mtlR Escherichia coli BW2952 mannitol repressor protein YP_002928487.1 3661921 D 595496 CDS YP_002928488.1 238902692 7953342 complement(3662520..3662729) 1 NC_012759.1 MG1655 equivalent: b4554; hypothetical protein 3662729 yibT 7953342 yibT Escherichia coli BW2952 hypothetical protein YP_002928488.1 3662520 R 595496 CDS YP_002928489.1 238902693 7955437 3663014..3663376 1 NC_012759.1 MG1655 equivalent: b3602; hypothetical protein 3663376 yibL 7955437 yibL Escherichia coli BW2952 hypothetical protein YP_002928489.1 3663014 D 595496 CDS YP_002928490.1 238902694 7953036 3663748..3665403 1 NC_012759.1 MG1655 equivalent: b3603; L-lactate permease 3665403 lldP 7953036 lldP Escherichia coli BW2952 L-lactate permease YP_002928490.1 3663748 D 595496 CDS YP_002928491.1 238902695 7954162 3665403..3666179 1 NC_012759.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3666179 lldR 7954162 lldR Escherichia coli BW2952 DNA-binding transcriptional repressor LldR YP_002928491.1 3665403 D 595496 CDS YP_002928492.1 238902696 7953469 3666176..3667366 1 NC_012759.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3667366 lldD 7953469 lldD Escherichia coli BW2952 L-lactate dehydrogenase YP_002928492.1 3666176 D 595496 CDS YP_002928493.1 238902697 7954161 3667564..3668037 1 NC_012759.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK 3668037 yibK 7954161 yibK Escherichia coli BW2952 putative tRNA/rRNA methyltransferase YibK YP_002928493.1 3667564 D 595496 CDS YP_002928494.1 238902698 7955574 complement(3668090..3668911) 1 NC_012759.1 catalyzes the O-acetylation of serine; serine acetyltransferase 3668911 cysE 7955574 cysE Escherichia coli BW2952 serine acetyltransferase YP_002928494.1 3668090 R 595496 CDS YP_002928495.1 238902699 7956028 complement(3668991..3670010) 1 NC_012759.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3670010 gpsA 7956028 gpsA Escherichia coli BW2952 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002928495.1 3668991 R 595496 CDS YP_002928496.1 238902700 7953848 complement(3670010..3670477) 1 NC_012759.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 3670477 secB 7953848 secB Escherichia coli BW2952 preprotein translocase subunit SecB YP_002928496.1 3670010 R 595496 CDS YP_002928497.1 238902701 7955792 complement(3670540..3670791) 1 NC_012759.1 MG1655 equivalent: b3610; glutaredoxin 3 3670791 grxC 7955792 grxC Escherichia coli BW2952 glutaredoxin 3 YP_002928497.1 3670540 R 595496 CDS YP_002928498.1 238902702 7953837 complement(3670933..3671364) 1 NC_012759.1 MG1655 equivalent: b3611; putative rhodanese-related sulfurtransferase 3671364 yibN 7953837 yibN Escherichia coli BW2952 putative rhodanese-related sulfurtransferase YP_002928498.1 3670933 R 595496 CDS YP_002928499.1 238902703 7955569 3671609..3673153 1 NC_012759.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3673153 gpmM 7955569 gpmM Escherichia coli BW2952 phosphoglyceromutase YP_002928499.1 3671609 D 595496 CDS YP_002928500.1 238902704 7954534 3673187..3674446 1 NC_012759.1 MG1655 equivalent: b3613; hypothetical protein 3674446 envC 7954534 envC Escherichia coli BW2952 hypothetical protein YP_002928500.1 3673187 D 595496 CDS YP_002928501.1 238902705 7955779 3674450..3675409 1 NC_012759.1 MG1655 equivalent: b3614; putative polysaccharide deacetylase 3675409 yibQ 7955779 yibQ Escherichia coli BW2952 putative polysaccharide deacetylase YP_002928501.1 3674450 D 595496 CDS YP_002928502.1 238902706 7955325 complement(3675396..3676430) 1 NC_012759.1 MG1655 equivalent: b3615; putative glycosyl transferase 3676430 yibD 7955325 yibD Escherichia coli BW2952 putative glycosyl transferase YP_002928502.1 3675396 R 595496 CDS YP_002928503.1 238902707 7954938 complement(3676669..3677694) 1 NC_012759.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 3677694 tdh 7954938 tdh Escherichia coli BW2952 L-threonine 3-dehydrogenase YP_002928503.1 3676669 R 595496 CDS YP_002928504.1 238902708 7956142 complement(3677704..3678900) 1 NC_012759.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 3678900 kbl 7956142 kbl Escherichia coli BW2952 2-amino-3-ketobutyrate coenzyme A ligase YP_002928504.1 3677704 R 595496 CDS YP_002928505.1 238902709 7953858 complement(3679175..3680032) 1 NC_012759.1 MG1655 equivalent: b3618; hypothetical protein 3680032 htrL 7953858 htrL Escherichia coli BW2952 hypothetical protein YP_002928505.1 3679175 R 595496 CDS YP_002928506.1 238902710 7955425 3680336..3681268 1 NC_012759.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 3681268 rfaD 7955425 rfaD Escherichia coli BW2952 ADP-L-glycero-D-manno-heptose-6-epimerase YP_002928506.1 3680336 D 595496 CDS YP_002928507.1 238902711 7952431 3681278..3682324 1 NC_012759.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 3682324 rfaF 7952431 rfaF Escherichia coli BW2952 ADP-heptose--LPS heptosyltransferase YP_002928507.1 3681278 D 595496 CDS YP_002928508.1 238902712 7952430 3682328..3683287 1 NC_012759.1 MG1655 equivalent: b3621; ADP-heptose--LPS heptosyltransferase 3683287 rfaC 7952430 rfaC Escherichia coli BW2952 ADP-heptose--LPS heptosyltransferase YP_002928508.1 3682328 D 595496 CDS YP_002928509.1 238902713 7952429 3683297..3684556 1 NC_012759.1 MG1655 equivalent: b3622; O-antigen ligase 3684556 rfaL 7952429 rfaL Escherichia coli BW2952 O-antigen ligase YP_002928509.1 3683297 D 595496 CDS YP_002928510.1 238902714 7954417 complement(3684588..3685661) 1 NC_012759.1 MG1655 equivalent: b3623; lipopolysaccharide core biosynthesis 3685661 waaU 7954417 waaU Escherichia coli BW2952 lipopolysaccharide core biosynthesis YP_002928510.1 3684588 R 595496 CDS YP_002928511.1 238902715 7954150 complement(3685694..3686545) 1 NC_012759.1 MG1655 equivalent: b3624; lipopolysaccharide core biosynthesis protein 3686545 rfaZ 7954150 rfaZ Escherichia coli BW2952 lipopolysaccharide core biosynthesis protein YP_002928511.1 3685694 R 595496 CDS YP_002928512.1 238902716 7954151 complement(3686616..3687314) 1 NC_012759.1 MG1655 equivalent: b3625; lipopolysaccharide core biosynthesis protein 3687314 rfaY 7954151 rfaY Escherichia coli BW2952 lipopolysaccharide core biosynthesis protein YP_002928512.1 3686616 R 595496 CDS YP_002928513.1 238902717 7954152 complement(3687332..3688348) 1 NC_012759.1 MG1655 equivalent: b3626; UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase 3688348 rfaJ 7954152 rfaJ Escherichia coli BW2952 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase YP_002928513.1 3687332 R 595496 CDS YP_002928514.1 238902718 7956230 complement(3688388..3689407) 1 NC_012759.1 MG1655 equivalent: b3627; UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase 3689407 rfaI 7956230 rfaI Escherichia coli BW2952 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase YP_002928514.1 3688388 R 595496 CDS YP_002928515.1 238902719 7956229 complement(3689407..3690516) 1 NC_012759.1 MG1655 equivalent: b3628; UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase 3690516 rfaB 7956229 rfaB Escherichia coli BW2952 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase YP_002928515.1 3689407 R 595496 CDS YP_002928516.1 238902720 7956228 complement(3690530..3691465) 1 NC_012759.1 MG1655 equivalent: b3629; lipopolysaccharide core biosynthesis protein 3691465 rfaS 7956228 rfaS Escherichia coli BW2952 lipopolysaccharide core biosynthesis protein YP_002928516.1 3690530 R 595496 CDS YP_002928517.1 238902721 7954153 complement(3691502..3692299) 1 NC_012759.1 MG1655 equivalent: b3630; kinase that phosphorylates core heptose of lipopolysaccharide 3692299 rfaP 7954153 rfaP Escherichia coli BW2952 kinase that phosphorylates core heptose of lipopolysaccharide YP_002928517.1 3691502 R 595496 CDS YP_002928518.1 238902722 7954061 complement(3692292..3693416) 1 NC_012759.1 MG1655 equivalent: b3631; glucosyltransferase I 3693416 rfaG 7954061 rfaG Escherichia coli BW2952 glucosyltransferase I YP_002928518.1 3692292 R 595496 CDS YP_002928519.1 238902723 7953813 complement(3693413..3694447) 1 NC_012759.1 MG1655 equivalent: b3632; lipopolysaccharide core biosynthesis protein 3694447 rfaQ 7953813 rfaQ Escherichia coli BW2952 lipopolysaccharide core biosynthesis protein YP_002928519.1 3693413 R 595496 CDS YP_002928520.1 238902724 7954154 3694889..3696166 1 NC_012759.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 3696166 waaA 7954154 waaA Escherichia coli BW2952 3-deoxy-D-manno-octulosonic-acid transferase YP_002928520.1 3694889 D 595496 CDS YP_002928521.1 238902725 7952302 3696174..3696653 1 NC_012759.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3696653 coaD 7952302 coaD Escherichia coli BW2952 phosphopantetheine adenylyltransferase YP_002928521.1 3696174 D 595496 CDS YP_002928522.1 238902726 7954463 complement(3696692..3697501) 1 NC_012759.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 3697501 mutM 7954463 mutM Escherichia coli BW2952 formamidopyrimidine-DNA glycosylase YP_002928522.1 3696692 R 595496 CDS YP_002928523.1 238902727 7953614 complement(3697599..3697766) 1 NC_012759.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 3697766 rpmG 7953614 rpmG Escherichia coli BW2952 50S ribosomal protein L33 YP_002928523.1 3697599 R 595496 CDS YP_002928524.1 238902728 7952361 complement(3697787..3698023) 1 NC_012759.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3698023 rpmB 7952361 rpmB Escherichia coli BW2952 50S ribosomal protein L28 YP_002928524.1 3697787 R 595496 CDS YP_002928525.1 238902729 7952355 complement(3698240..3698908) 1 NC_012759.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 3698908 radC 7952355 radC Escherichia coli BW2952 DNA repair protein RadC YP_002928525.1 3698240 R 595496 CDS YP_002928526.1 238902730 7955783 3699080..3700300 1 NC_012759.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3700300 dfp 7955783 dfp Escherichia coli BW2952 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002928526.1 3699080 D 595496 CDS YP_002928527.1 238902731 7953651 3700281..3700736 1 NC_012759.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3700736 dut 7953651 dut Escherichia coli BW2952 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002928527.1 3700281 D 595496 CDS YP_002928528.1 238902732 7953237 3700843..3701439 1 NC_012759.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 3701439 slmA 7953237 slmA Escherichia coli BW2952 nucleoid occlusion protein YP_002928528.1 3700843 D 595496 CDS YP_002928529.1 238902733 7953271 complement(3701476..3702117) 1 NC_012759.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 3702117 pyrE 7953271 pyrE Escherichia coli BW2952 orotate phosphoribosyltransferase YP_002928529.1 3701476 R 595496 CDS YP_002928530.1 238902734 7954431 complement(3702183..3702899) 1 NC_012759.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 3702899 rph 7954431 rph Escherichia coli BW2952 ribonuclease PH YP_002928530.1 3702183 R 595496 CDS YP_002928531.1 238902735 7953231 3703026..3703889 1 NC_012759.1 MG1655 equivalent: b3644; hypothetical protein 3703889 yicC 7953231 yicC Escherichia coli BW2952 hypothetical protein YP_002928531.1 3703026 D 595496 CDS YP_002928532.1 238902736 7953037 3704110..3704934 1 NC_012759.1 MG1655 equivalent: b3645; DNA-damage-inducible protein D 3704934 dinD 7953037 dinD Escherichia coli BW2952 DNA-damage-inducible protein D YP_002928532.1 3704110 D 595496 CDS YP_002928533.1 238902737 7953485 3705224..3705841 1 NC_012759.1 MG1655 equivalent: b3646; hypothetical protein 3705841 yicG 7953485 yicG Escherichia coli BW2952 hypothetical protein YP_002928533.1 3705224 D 595496 CDS YP_002928534.1 238902738 7952731 complement(3705838..3707520) 1 NC_012759.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 3707520 ligB 7952731 ligB Escherichia coli BW2952 NAD-dependent DNA ligase LigB YP_002928534.1 3705838 R 595496 CDS YP_002928535.1 238902739 7953312 3707778..3708401 1 NC_012759.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3708401 gmk 7953312 gmk Escherichia coli BW2952 guanylate kinase YP_002928535.1 3707778 D 595496 CDS YP_002928536.1 238902740 7953887 3708456..3708731 1 NC_012759.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3708731 rpoZ 7953887 rpoZ Escherichia coli BW2952 DNA-directed RNA polymerase subunit omega YP_002928536.1 3708456 D 595496 CDS YP_002928537.1 238902741 7955986 3708750..3710864 1 NC_012759.1 MG1655 equivalent: b3650; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3710864 spoT 7955986 spoT Escherichia coli BW2952 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_002928537.1 3708750 D 595496 CDS YP_002928538.1 238902742 7952555 3710871..3711560 1 NC_012759.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 3711560 trmH 7952555 trmH Escherichia coli BW2952 tRNA guanosine-2'-O-methyltransferase YP_002928538.1 3710871 D 595496 CDS YP_002928539.1 238902743 7956197 3711566..3713647 1 NC_012759.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3713647 recG 7956197 recG Escherichia coli BW2952 ATP-dependent DNA helicase RecG YP_002928539.1 3711566 D 595496 CDS YP_002928540.1 238902744 7952530 complement(3713816..3715021) 1 NC_012759.1 MG1655 equivalent: b3653; glutamate transporter 3715021 gltS 7952530 gltS Escherichia coli BW2952 glutamate transporter YP_002928540.1 3713816 R 595496 CDS YP_002928541.1 238902745 7953824 3715301..3716692 1 NC_012759.1 MG1655 equivalent: b3654; putative transporter 3716692 yicE 7953824 yicE Escherichia coli BW2952 putative transporter YP_002928541.1 3715301 D 595496 CDS YP_002928542.1 238902746 7955711 3716813..3718522 1 NC_012759.1 MG1655 equivalent: b3655; hypothetical protein 3718522 yicH 7955711 yicH Escherichia coli BW2952 hypothetical protein YP_002928542.1 3716813 D 595496 CDS YP_002928543.1 238902747 7953038 complement(3718575..3720893) 1 NC_012759.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 3720893 yicI 7953038 yicI Escherichia coli BW2952 alpha-xylosidase YP_002928543.1 3718575 R 595496 CDS YP_002928544.1 238902748 7954634 complement(3720903..3722285) 1 NC_012759.1 may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter 3722285 yicJ 7954634 yicJ Escherichia coli BW2952 putative transporter YP_002928544.1 3720903 R 595496 CDS YP_002928545.1 238902749 7952147 3723309..3724493 1 NC_012759.1 MG1655 equivalent: b3659; putative sugar efflux system 3724493 setC 7952147 setC Escherichia coli BW2952 putative sugar efflux system YP_002928545.1 3723309 D 595496 CDS YP_002928546.1 238902750 7955603 3724604..3725527 1 NC_012759.1 MG1655 equivalent: b3660; putative inner membrane protein 3725527 yicL 7955603 yicL Escherichia coli BW2952 putative inner membrane protein YP_002928546.1 3724604 D 595496 CDS YP_002928547.1 238902751 7955069 complement(3725531..3726349) 1 NC_012759.1 MG1655 equivalent: b3661; hypothetical protein 3726349 nlpA 7955069 nlpA Escherichia coli BW2952 hypothetical protein YP_002928547.1 3725531 R 595496 CDS YP_002928548.1 238902752 7953204 3726571..3726864 1 NC_012759.1 MG1655 equivalent: b4555; hypothetical protein 3726864 yicS 7953204 yicS Escherichia coli BW2952 hypothetical protein YP_002928548.1 3726571 D 595496 CDS YP_002928549.1 238902753 7955537 complement(3726905..3728095) 1 NC_012759.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 3728095 nepI 7955537 nepI Escherichia coli BW2952 ribonucleoside transporter YP_002928549.1 3726905 R 595496 CDS YP_002928550.1 238902754 7955669 complement(3728306..3728758) 1 NC_012759.1 MG1655 equivalent: b3663; hypothetical protein 3728758 yicN 7955669 yicN Escherichia coli BW2952 hypothetical protein YP_002928550.1 3728306 R 595496 CDS YP_002928551.1 238902755 7952888 complement(3728811..3730145) 1 NC_012759.1 MG1655 equivalent: b3664; putative xanthine/uracil permase 3730145 yicO 7952888 yicO Escherichia coli BW2952 putative xanthine/uracil permase YP_002928551.1 3728811 R 595496 CDS YP_002928552.1 238902756 7955752 3730320..3732086 1 NC_012759.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 3732086 ade 7955752 ade Escherichia coli BW2952 cryptic adenine deaminase YP_002928552.1 3730320 D 595496 CDS YP_002928553.1 238902757 7953166 complement(3732132..3733523) 1 NC_012759.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 3733523 uhpT 7953166 uhpT Escherichia coli BW2952 sugar phosphate antiporter YP_002928553.1 3732132 R 595496 CDS YP_002928554.1 238902758 7953905 complement(3733661..3734980) 1 NC_012759.1 membrane protein regulates uhpT expression; regulatory protein UhpC 3734980 uhpC 7953905 uhpC Escherichia coli BW2952 regulatory protein UhpC YP_002928554.1 3733661 R 595496 CDS YP_002928555.1 238902759 7954230 complement(3734990..3736492) 1 NC_012759.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 3736492 uhpB 7954230 uhpB Escherichia coli BW2952 sensory histidine kinase UhpB YP_002928555.1 3734990 R 595496 CDS YP_002928556.1 238902760 7956027 complement(3736492..3737082) 1 NC_012759.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 3737082 uhpA 7956027 uhpA Escherichia coli BW2952 DNA-binding transcriptional activator UhpA YP_002928556.1 3736492 R 595496 CDS YP_002928557.1 238902761 7953363 complement(3737158..3737448) 1 NC_012759.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 3737448 ilvN 7953363 ilvN Escherichia coli BW2952 acetolactate synthase 1 regulatory subunit YP_002928557.1 3737158 R 595496 CDS YP_002928558.1 238902762 7952391 complement(3737452..3739140) 1 NC_012759.1 MG1655 equivalent: b3671; acetolactate synthase catalytic subunit 3739140 ilvB 7952391 ilvB Escherichia coli BW2952 acetolactate synthase catalytic subunit YP_002928558.1 3737452 R 595496 CDS YP_002928559.1 238902763 7952390 complement(3739246..3739344) 1 NC_012759.1 MG1655 equivalent: b3672; ilvB operon leader peptide 3739344 ivbL 7952390 ivbL Escherichia coli BW2952 ilvB operon leader peptide YP_002928559.1 3739246 R 595496 CDS YP_002928560.1 238902764 7952097 3739799..3739912 1 NC_012759.1 MG1655 equivalent: b4617; hypothetical protein 3739912 tisA 7952097 tisA Escherichia coli BW2952 hypothetical protein YP_002928560.1 3739799 D 595496 CDS YP_002928561.1 238902765 7954134 3739909..3739998 1 NC_012759.1 MG1655 equivalent: b4618; toxic peptide TisB 3739998 tisB 7954134 tisB Escherichia coli BW2952 toxic peptide TisB YP_002928561.1 3739909 D 595496 CDS YP_002928562.1 238902766 7954135 3740278..3741462 1 NC_012759.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 3741462 emrD 7954135 emrD Escherichia coli BW2952 multidrug resistance protein D YP_002928562.1 3740278 D 595496 CDS YP_002928563.1 238902767 7954305 complement(3741470..3741967) 1 NC_012759.1 MG1655 equivalent: b3674; putative DNA-binding transcriptional regulator 3741967 yidF 7954305 yidF Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928563.1 3741470 R 595496 CDS YP_002928564.1 238902768 7954784 complement(3741964..3742326) 1 NC_012759.1 MG1655 equivalent: b3675; putative inner membrane protein 3742326 yidG 7954784 yidG Escherichia coli BW2952 putative inner membrane protein YP_002928564.1 3741964 R 595496 CDS YP_002928565.1 238902769 7955013 complement(3742316..3742663) 1 NC_012759.1 MG1655 equivalent: b3676; hypothetical protein 3742663 yidH 7955013 yidH Escherichia coli BW2952 hypothetical protein YP_002928565.1 3742316 R 595496 CDS YP_002928566.1 238902770 7952690 3742771..3743220 1 NC_012759.1 MG1655 equivalent: b3677; putative inner membrane protein 3743220 yidI 7952690 yidI Escherichia coli BW2952 putative inner membrane protein YP_002928566.1 3742771 D 595496 CDS YP_002928567.1 238902771 7955070 complement(3743267..3744760) 1 NC_012759.1 MG1655 equivalent: b3678; putative sulfatase/phosphatase 3744760 yidJ 7955070 yidJ Escherichia coli BW2952 putative sulfatase/phosphatase YP_002928567.1 3743267 R 595496 CDS YP_002928568.1 238902772 7955615 complement(3744757..3746472) 1 NC_012759.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK 3746472 yidK 7955615 yidK Escherichia coli BW2952 putative symporter YidK YP_002928568.1 3744757 R 595496 CDS YP_002928569.1 238902773 7955670 3746609..3747532 1 NC_012759.1 MG1655 equivalent: b3680; putative DNA-binding transcriptional regulator 3747532 yidL 7955670 yidL Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928569.1 3746609 D 595496 CDS YP_002928570.1 238902774 7954813 3750255..3750971 1 NC_012759.1 MG1655 equivalent: b3684; putative DNA-binding transcriptional regulator 3750971 yidP 7954813 yidP Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928570.1 3750255 D 595496 CDS YP_002928571.1 238902775 7954814 complement(3750968..3752629) 1 NC_012759.1 MG1655 equivalent: b3685; hypothetical protein 3752629 yidE 7954814 yidE Escherichia coli BW2952 hypothetical protein YP_002928571.1 3750968 R 595496 CDS YP_002928572.1 238902776 7955671 complement(3752825..3753253) 1 NC_012759.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 3753253 ibpB 7955671 ibpB Escherichia coli BW2952 heat shock chaperone IbpB YP_002928572.1 3752825 R 595496 CDS YP_002928573.1 238902777 7953890 complement(3753365..3753778) 1 NC_012759.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 3753778 ibpA 7953890 ibpA Escherichia coli BW2952 heat shock protein IbpA YP_002928573.1 3753365 R 595496 CDS YP_002928574.1 238902778 7953891 3754084..3754416 1 NC_012759.1 MG1655 equivalent: b3688; hypothetical protein 3754416 yidQ 7953891 yidQ Escherichia coli BW2952 hypothetical protein YP_002928574.1 3754084 D 595496 CDS YP_002928575.1 238902779 7952752 complement(3754418..3755632) 1 NC_012759.1 MG1655 equivalent: b3689; hypothetical protein 3755632 yidR 7952752 yidR Escherichia coli BW2952 hypothetical protein YP_002928575.1 3754418 R 595496 CDS YP_002928576.1 238902780 7952889 3755733..3756797 1 NC_012759.1 FAD/NAD(P)-binding domain; putative oxidoreductase 3756797 cbrA 7952889 cbrA Escherichia coli BW2952 putative oxidoreductase YP_002928576.1 3755733 D 595496 CDS YP_002928577.1 238902781 7955244 complement(3756794..3758086) 1 NC_012759.1 MG1655 equivalent: b3691; D-galactonate transporter 3758086 dgoT 7955244 dgoT Escherichia coli BW2952 D-galactonate transporter YP_002928577.1 3756794 R 595496 CDS YP_002928578.1 238902782 7953242 complement(3758206..3759354) 1 NC_012759.1 MG1655 equivalent: b4478; galactonate dehydratase 3759354 dgoD 7953242 dgoD Escherichia coli BW2952 galactonate dehydratase YP_002928578.1 3758206 R 595496 CDS YP_002928579.1 238902783 7953759 complement(3759351..3759968) 1 NC_012759.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 3759968 dgoA 7953759 dgoA Escherichia coli BW2952 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_002928579.1 3759351 R 595496 CDS YP_002928580.1 238902784 7952267 complement(3759952..3760830) 1 NC_012759.1 MG1655 equivalent: b3693; 2-oxo-3-deoxygalactonate kinase 3760830 dgoK 7952267 dgoK Escherichia coli BW2952 2-oxo-3-deoxygalactonate kinase YP_002928580.1 3759952 R 595496 CDS YP_002928581.1 238902785 7952268 complement(3760827..3761516) 1 NC_012759.1 MG1655 equivalent: b4479; putative DNA-binding transcriptional regulator 3761516 dgoR 7952268 dgoR Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928581.1 3760827 R 595496 CDS YP_002928582.1 238902786 7954788 3761794..3762450 1 NC_012759.1 MG1655 equivalent: b3696; hypothetical protein 3762450 yidX 7954788 yidX Escherichia coli BW2952 hypothetical protein YP_002928582.1 3761794 D 595496 CDS YP_002928583.1 238902787 7955122 complement(3762496..3763308) 1 NC_012759.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 3763308 yidA 7955122 yidA Escherichia coli BW2952 sugar phosphatase YP_002928583.1 3762496 R 595496 CDS YP_002928584.1 238902788 7954961 complement(3763423..3763821) 1 NC_012759.1 MG1655 equivalent: b3698; hypothetical protein 3763821 yidB 7954961 yidB Escherichia coli BW2952 hypothetical protein YP_002928584.1 3763423 R 595496 CDS YP_002928585.1 238902789 7952890 complement(3764061..3766475) 1 NC_012759.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 3766475 gyrB 7952890 gyrB Escherichia coli BW2952 DNA gyrase subunit B YP_002928585.1 3764061 R 595496 CDS YP_002928586.1 238902790 7953308 complement(3766504..3767577) 1 NC_012759.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3767577 recF 7953308 recF Escherichia coli BW2952 recombination protein F YP_002928586.1 3766504 R 595496 CDS YP_002928587.1 238902791 7953774 complement(3767577..3768677) 1 NC_012759.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3768677 dnaN 7953774 dnaN Escherichia coli BW2952 DNA polymerase III subunit beta YP_002928587.1 3767577 R 595496 CDS YP_002928588.1 238902792 7953320 complement(3768682..3770085) 1 NC_012759.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 3770085 dnaA 7953320 dnaA Escherichia coli BW2952 chromosomal replication initiation protein YP_002928588.1 3768682 R 595496 CDS YP_002928589.1 238902793 7952638 3770692..3770832 1 NC_012759.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3770832 rpmH 7952638 rpmH Escherichia coli BW2952 50S ribosomal protein L34 YP_002928589.1 3770692 D 595496 CDS YP_002928590.1 238902794 7952362 3770849..3771208 1 NC_012759.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 3771208 rnpA 7952362 rnpA Escherichia coli BW2952 ribonuclease P YP_002928590.1 3770849 D 595496 CDS YP_002928591.1 238902795 7955784 3771172..3771429 1 NC_012759.1 MG1655 equivalent: b4557; hypothetical protein 3771429 yidD 7955784 yidD Escherichia coli BW2952 hypothetical protein YP_002928591.1 3771172 D 595496 CDS YP_002928592.1 238902796 7955538 3771432..3773078 1 NC_012759.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3773078 yidC 7955538 yidC Escherichia coli BW2952 putative inner membrane protein translocase component YidC YP_002928592.1 3771432 D 595496 CDS YP_002928593.1 238902797 7953201 3773184..3774548 1 NC_012759.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3774548 trmE 7953201 trmE Escherichia coli BW2952 tRNA modification GTPase TrmE YP_002928593.1 3773184 D 595496 CDS YP_002928594.1 238902798 7953878 3774791..3774865 1 NC_012759.1 MG1655 equivalent: b3707; tryptophanase leader peptide 3774865 tnaC 7953878 tnaC Escherichia coli BW2952 tryptophanase leader peptide YP_002928594.1 3774791 D 595496 CDS YP_002928595.1 238902799 7956215 3775086..3776501 1 NC_012759.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 3776501 tnaA 7956215 tnaA Escherichia coli BW2952 tryptophanase YP_002928595.1 3775086 D 595496 CDS YP_002928596.1 238902800 7956216 3776592..3777839 1 NC_012759.1 tryptophan transporter of low affinity; tryptophan permease TnaB 3777839 tnaB 7956216 tnaB Escherichia coli BW2952 tryptophan permease TnaB YP_002928596.1 3776592 D 595496 CDS YP_002928597.1 238902801 7956214 3777971..3779146 1 NC_012759.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 3779146 mdtL 7956214 mdtL Escherichia coli BW2952 multidrug efflux system protein MdtL YP_002928597.1 3777971 D 595496 CDS YP_002928598.1 238902802 7954306 3779121..3780080 1 NC_012759.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 3780080 yidZ 7954306 yidZ Escherichia coli BW2952 DNA-binding transcriptional regulator YidZ YP_002928598.1 3779121 D 595496 CDS YP_002928599.1 238902803 7954815 3780225..3780986 1 NC_012759.1 MG1655 equivalent: b3712; putative phosphopantetheinyl transferase 3780986 yieE 7954815 yieE Escherichia coli BW2952 putative phosphopantetheinyl transferase YP_002928599.1 3780225 D 595496 CDS YP_002928600.1 238902804 7955317 3781008..3781574 1 NC_012759.1 MG1655 equivalent: b3713; chromate reductase, Class I, flavoprotein 3781574 yieF 7955317 yieF Escherichia coli BW2952 chromate reductase, Class I, flavoprotein YP_002928600.1 3781008 D 595496 CDS YP_002928601.1 238902805 7952637 complement(3781628..3782965) 1 NC_012759.1 MG1655 equivalent: b3714; putative inner membrane protein 3782965 yieG 7952637 yieG Escherichia coli BW2952 putative inner membrane protein YP_002928601.1 3781628 R 595496 CDS YP_002928602.1 238902806 7955014 3783130..3783795 1 NC_012759.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 3783795 yieH 7955014 yieH Escherichia coli BW2952 6-phosphogluconate phosphatase YP_002928602.1 3783130 D 595496 CDS YP_002928603.1 238902807 7954971 3783862..3784329 1 NC_012759.1 might be involved in hypersensitivity to nitrofurzone; putative inner membrane protein 3784329 cbrB 7954971 cbrB Escherichia coli BW2952 putative inner membrane protein YP_002928603.1 3783862 D 595496 CDS YP_002928604.1 238902808 7955071 3784378..3784965 1 NC_012759.1 MG1655 equivalent: b3717; hypothetical protein 3784965 cbrC 7955071 cbrC Escherichia coli BW2952 hypothetical protein YP_002928604.1 3784378 D 595496 CDS YP_002928605.1 238902809 7953039 complement(3785027..3785749) 1 NC_012759.1 MG1655 equivalent: b3718; putative 6-phosphogluconolactonase 3785749 yieK 7953039 yieK Escherichia coli BW2952 putative 6-phosphogluconolactonase YP_002928605.1 3785027 R 595496 CDS YP_002928606.1 238902810 7954598 complement(3785764..3786933) 1 NC_012759.1 MG1655 equivalent: b3719; putative xylanase 3786933 yieL 7954598 yieL Escherichia coli BW2952 putative xylanase YP_002928606.1 3785764 R 595496 CDS YP_002928607.1 238902811 7955753 complement(3786960..3788576) 1 NC_012759.1 MG1655 equivalent: b3720; carbohydrate-specific outer membrane porin, cryptic 3788576 bglH 7955753 bglH Escherichia coli BW2952 carbohydrate-specific outer membrane porin, cryptic YP_002928607.1 3786960 R 595496 CDS YP_002928608.1 238902812 7952595 complement(3788645..3790057) 1 NC_012759.1 MG1655 equivalent: b3721; cryptic phospho-beta-glucosidase B 3790057 bglB 7952595 bglB Escherichia coli BW2952 cryptic phospho-beta-glucosidase B YP_002928608.1 3788645 R 595496 CDS YP_002928609.1 238902813 7953171 complement(3790076..3791953) 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 3791953 bglF 7953171 bglF Escherichia coli BW2952 PTS system beta-glucoside-specific transporter subunit IIABC YP_002928609.1 3790076 R 595496 CDS YP_002928610.1 238902814 7953659 complement(3792087..3792923) 1 NC_012759.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 3792923 bglG 7953659 bglG Escherichia coli BW2952 transcriptional antiterminator BglG YP_002928610.1 3792087 R 595496 CDS YP_002928611.1 238902815 7956172 complement(3793209..3793934) 1 NC_012759.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 3793934 phoU 7956172 phoU Escherichia coli BW2952 transcriptional regulator PhoU YP_002928611.1 3793209 R 595496 CDS YP_002928612.1 238902816 7954371 complement(3793949..3794722) 1 NC_012759.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 3794722 pstB 7954371 pstB Escherichia coli BW2952 phosphate transporter ATP-binding protein YP_002928612.1 3793949 R 595496 CDS YP_002928613.1 238902817 7954515 complement(3794905..3795795) 1 NC_012759.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 3795795 pstA 7954515 pstA Escherichia coli BW2952 phosphate transporter permease subunit PtsA YP_002928613.1 3794905 R 595496 CDS YP_002928614.1 238902818 7954516 complement(3795795..3796754) 1 NC_012759.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 3796754 pstC 7954516 pstC Escherichia coli BW2952 phosphate transporter permease subunit PstC YP_002928614.1 3795795 R 595496 CDS YP_002928615.1 238902819 7954517 complement(3796841..3797881) 1 NC_012759.1 MG1655 equivalent: b3728; phosphate ABC transporter substrate-binding protein 3797881 pstS 7954517 pstS Escherichia coli BW2952 phosphate ABC transporter substrate-binding protein YP_002928615.1 3796841 R 595496 CDS YP_002928616.1 238902820 7954518 complement(3798195..3800024) 1 NC_012759.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 3800024 glmS 7954518 glmS Escherichia coli BW2952 glucosamine--fructose-6-phosphate aminotransferase YP_002928616.1 3798195 R 595496 CDS YP_002928617.1 238902821 7954141 complement(3800186..3801556) 1 NC_012759.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 3801556 glmU 7954141 glmU Escherichia coli BW2952 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002928617.1 3800186 R 595496 CDS YP_002928618.1 238902822 7953703 complement(3801909..3802328) 1 NC_012759.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 3802328 atpC 7953703 atpC Escherichia coli BW2952 F0F1 ATP synthase subunit epsilon YP_002928618.1 3801909 R 595496 CDS YP_002928619.1 238902823 7953559 complement(3802349..3803731) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 3803731 atpD 7953559 atpD Escherichia coli BW2952 F0F1 ATP synthase subunit beta YP_002928619.1 3802349 R 595496 CDS YP_002928620.1 238902824 7953557 complement(3803758..3804621) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 3804621 atpG 7953557 atpG Escherichia coli BW2952 F0F1 ATP synthase subunit gamma YP_002928620.1 3803758 R 595496 CDS YP_002928621.1 238902825 7953560 complement(3804672..3806213) 1 NC_012759.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 3806213 atpA 7953560 atpA Escherichia coli BW2952 F0F1 ATP synthase subunit alpha YP_002928621.1 3804672 R 595496 CDS YP_002928622.1 238902826 7953556 complement(3806226..3806759) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 3806759 atpH 7953556 atpH Escherichia coli BW2952 F0F1 ATP synthase subunit delta YP_002928622.1 3806226 R 595496 CDS YP_002928623.1 238902827 7953558 complement(3806774..3807244) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 3807244 atpF 7953558 atpF Escherichia coli BW2952 F0F1 ATP synthase subunit B YP_002928623.1 3806774 R 595496 CDS YP_002928624.1 238902828 7953554 complement(3807306..3807545) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 3807545 atpE 7953554 atpE Escherichia coli BW2952 F0F1 ATP synthase subunit C YP_002928624.1 3807306 R 595496 CDS YP_002928625.1 238902829 7953555 complement(3807592..3808407) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 3808407 atpB 7953555 atpB Escherichia coli BW2952 F0F1 ATP synthase subunit A YP_002928625.1 3807592 R 595496 CDS YP_002928626.1 238902830 7953553 complement(3808416..3808796) 1 NC_012759.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 3808796 atpI 7953553 atpI Escherichia coli BW2952 F0F1 ATP synthase subunit I YP_002928626.1 3808416 R 595496 CDS YP_002928627.1 238902831 7952522 complement(3809413..3810036) 1 NC_012759.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 3810036 gidB 7952522 gidB Escherichia coli BW2952 16S rRNA methyltransferase GidB YP_002928627.1 3809413 R 595496 CDS YP_002928628.1 238902832 7954262 complement(3810100..3811989) 1 NC_012759.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 3811989 mnmG 7954262 mnmG Escherichia coli BW2952 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002928628.1 3810100 R 595496 CDS YP_002928629.1 238902833 7953810 complement(3812368..3812811) 1 NC_012759.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3812811 mioC 7953810 mioC Escherichia coli BW2952 flavodoxin YP_002928629.1 3812368 R 595496 CDS YP_002928630.1 238902834 7953613 complement(3812901..3813359) 1 NC_012759.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 3813359 asnC 7953613 asnC Escherichia coli BW2952 DNA-binding transcriptional regulator AsnC YP_002928630.1 3812901 R 595496 CDS YP_002928631.1 238902835 7953412 3813511..3814503 1 NC_012759.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 3814503 asnA 7953412 asnA Escherichia coli BW2952 asparagine synthetase AsnA YP_002928631.1 3813511 D 595496 CDS YP_002928632.1 238902836 7952507 complement(3814508..3815959) 1 NC_012759.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 3815959 yieM 7952507 yieM Escherichia coli BW2952 hypothetical protein YP_002928632.1 3814508 R 595496 CDS YP_002928633.1 238902837 7955750 complement(3815953..3817449) 1 NC_012759.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 3817449 ravA 7955750 ravA Escherichia coli BW2952 regulatory ATPase RavA YP_002928633.1 3815953 R 595496 CDS YP_002928634.1 238902838 7953729 3817672..3819540 1 NC_012759.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 3819540 trkD 7953729 trkD Escherichia coli BW2952 potassium transport protein Kup YP_002928634.1 3817672 D 595496 CDS YP_002928635.1 238902839 7954576 3819707..3820126 1 NC_012759.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 3820126 rbsD 7954576 rbsD Escherichia coli BW2952 D-ribose pyranase YP_002928635.1 3819707 D 595496 CDS YP_002928636.1 238902840 7954710 3820134..3821639 1 NC_012759.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 3821639 rbsA 7954710 rbsA Escherichia coli BW2952 D-ribose transporter ATP-binding protein YP_002928636.1 3820134 D 595496 CDS YP_002928637.1 238902841 7953677 3821644..3822609 1 NC_012759.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 3822609 rbsC 7953677 rbsC Escherichia coli BW2952 ribose ABC transporter permease YP_002928637.1 3821644 D 595496 CDS YP_002928638.1 238902842 7953493 3822634..3823524 1 NC_012759.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 3823524 rbsB 7953493 rbsB Escherichia coli BW2952 D-ribose transporter subunit RbsB YP_002928638.1 3822634 D 595496 CDS YP_002928639.1 238902843 7953494 3823650..3824579 1 NC_012759.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 3824579 rbsK 7953494 rbsK Escherichia coli BW2952 ribokinase YP_002928639.1 3823650 D 595496 CDS YP_002928640.1 238902844 7955918 3825220..3825585 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3825585 7955918 BWG_3445 Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002928640.1 3825220 D 595496 CDS YP_002928641.1 238902845 7954008 3825543..3826448 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3826448 7954008 BWG_3446 Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002928641.1 3825543 D 595496 CDS YP_002928642.1 238902846 7952209 complement(3826877..3828304) 1 NC_012759.1 MG1655 equivalent: b3754; putative multidrug or homocysteine efflux system 3828304 hsrA 7952209 hsrA Escherichia coli BW2952 putative multidrug or homocysteine efflux system YP_002928642.1 3826877 R 595496 CDS YP_002928643.1 238902847 7955175 complement(3828327..3829019) 1 NC_012759.1 MG1655 equivalent: b3755; putative transcriptional regulator 3829019 yieP 7955175 yieP Escherichia coli BW2952 putative transcriptional regulator YP_002928643.1 3828327 R 595496 CDS YP_002928644.1 238902848 7952150 complement(3834820..3835659) 1 NC_012759.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 3835659 hdfR 7952150 hdfR Escherichia coli BW2952 transcriptional regulator HdfR YP_002928644.1 3834820 R 595496 CDS YP_002928645.1 238902849 7953441 3835778..3836116 1 NC_012759.1 MG1655 equivalent: b3764; hypothetical protein 3836116 yifE 7953441 yifE Escherichia coli BW2952 hypothetical protein YP_002928645.1 3835778 D 595496 CDS YP_002928646.1 238902850 7953040 complement(3836141..3837661) 1 NC_012759.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease 3837661 yifB 7953040 yifB Escherichia coli BW2952 putative ATP-dependent protease YP_002928646.1 3836141 R 595496 CDS YP_002928647.1 238902851 7954670 3838014..3838112 1 NC_012759.1 MG1655 equivalent: b3766; ilvG operon leader peptide 3838112 ilvL 7954670 ilvL Escherichia coli BW2952 ilvG operon leader peptide YP_002928647.1 3838014 D 595496 CDS YP_002928648.1 238902852 7953990 3839893..3840156 1 NC_012759.1 MG1655 equivalent: b3769; acetolactate synthase 2 regulatory subunit 3840156 ilvM 7953990 ilvM Escherichia coli BW2952 acetolactate synthase 2 regulatory subunit YP_002928648.1 3839893 D 595496 CDS YP_002928649.1 238902853 7952392 3840176..3841105 1 NC_012759.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 3841105 ilvE 7952392 ilvE Escherichia coli BW2952 branched-chain amino acid aminotransferase YP_002928649.1 3840176 D 595496 CDS YP_002928650.1 238902854 7952583 3841170..3843020 1 NC_012759.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 3843020 ilvD 7952583 ilvD Escherichia coli BW2952 dihydroxy-acid dehydratase YP_002928650.1 3841170 D 595496 CDS YP_002928651.1 238902855 7953259 3843023..3844567 1 NC_012759.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 3844567 ilvA 7953259 ilvA Escherichia coli BW2952 threonine dehydratase YP_002928651.1 3843023 D 595496 CDS YP_002928652.1 238902856 7956144 complement(3844619..3845512) 1 NC_012759.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 3845512 ilvY 7956144 ilvY Escherichia coli BW2952 DNA-binding transcriptional regulator IlvY YP_002928652.1 3844619 R 595496 CDS YP_002928653.1 238902857 7953413 3845662..3847137 1 NC_012759.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 3847137 ilvC 7953413 ilvC Escherichia coli BW2952 ketol-acid reductoisomerase YP_002928653.1 3845662 D 595496 CDS YP_002928654.1 238902858 7954060 complement(3847224..3847505) 1 NC_012759.1 MG1655 equivalent: b3775; peptidyl-prolyl cis-trans isomerase C 3847505 ppiC 7954060 ppiC Escherichia coli BW2952 peptidyl-prolyl cis-trans isomerase C YP_002928654.1 3847224 R 595496 CDS YP_002928655.1 238902859 7954484 3848369..3850390 1 NC_012759.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 3850390 rep 7954484 rep Escherichia coli BW2952 ATP-dependent DNA helicase Rep YP_002928655.1 3848369 D 595496 CDS YP_002928656.1 238902860 7953309 complement(3850437..3851921) 1 NC_012759.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 3851921 gpp 7953309 gpp Escherichia coli BW2952 guanosine pentaphosphate phosphohydrolase YP_002928656.1 3850437 R 595496 CDS YP_002928657.1 238902861 7953886 complement(3852057..3853322) 1 NC_012759.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 3853322 rhlB 7953886 rhlB Escherichia coli BW2952 ATP-dependent RNA helicase RhlB YP_002928657.1 3852057 R 595496 CDS YP_002928658.1 238902862 7952535 3853453..3853782 1 NC_012759.1 MG1655 equivalent: b3781; thioredoxin 3853782 trxA 7952535 trxA Escherichia coli BW2952 thioredoxin YP_002928658.1 3853453 D 595496 CDS YP_002928659.1 238902863 7956134 3854109..3855368 1 NC_012759.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 3855368 rho 7956134 rho Escherichia coli BW2952 transcription termination factor Rho YP_002928659.1 3854109 D 595496 CDS YP_002928660.1 238902864 7956169 3855608..3856711 1 NC_012759.1 MG1655 equivalent: b3784; UDP-GlcNAc:UDPphosphate GlcNAc-1-phosphate transferase 3856711 rfe 7956169 rfe Escherichia coli BW2952 UDP-GlcNAc:UDPphosphate GlcNAc-1-phosphate transferase YP_002928660.1 3855608 D 595496 CDS YP_002928661.1 238902865 7956233 3856723..3857769 1 NC_012759.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 3857769 wzzE 7956233 wzzE Escherichia coli BW2952 lipopolysaccharide biosynthesis protein WzzE YP_002928661.1 3856723 D 595496 CDS YP_002928662.1 238902866 7953529 3857825..3858955 1 NC_012759.1 MG1655 equivalent: b3786; UDP-N-acetyl glucosamine-2-epimerase 3858955 rffE 7953529 rffE Escherichia coli BW2952 UDP-N-acetyl glucosamine-2-epimerase YP_002928662.1 3857825 D 595496 CDS YP_002928663.1 238902867 7956235 3858952..3860214 1 NC_012759.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 3860214 wecC 7956235 wecC Escherichia coli BW2952 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002928663.1 3858952 D 595496 CDS YP_002928664.1 238902868 7956236 3860214..3861281 1 NC_012759.1 MG1655 equivalent: b3788; dTDP-glucose 4,6-dehydratase 3861281 rffG 7956236 rffG Escherichia coli BW2952 dTDP-glucose 4,6-dehydratase YP_002928664.1 3860214 D 595496 CDS YP_002928665.1 238902869 7953504 3861300..3862181 1 NC_012759.1 MG1655 equivalent: b3789; glucose-1-phosphate thymidylyltransferase 3862181 rffH 7953504 rffH Escherichia coli BW2952 glucose-1-phosphate thymidylyltransferase YP_002928665.1 3861300 D 595496 CDS YP_002928666.1 238902870 7953807 3862159..3862833 1 NC_012759.1 MG1655 equivalent: b3790; TDP-fucosamine acetyltransferase 3862833 rffC 7953807 rffC Escherichia coli BW2952 TDP-fucosamine acetyltransferase YP_002928666.1 3862159 D 595496 CDS YP_002928667.1 238902871 7956119 3862838..3863968 1 NC_012759.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 3863968 rffA 7956119 rffA Escherichia coli BW2952 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002928667.1 3862838 D 595496 CDS YP_002928668.1 238902872 7956117 3863970..3865220 1 NC_012759.1 MG1655 equivalent: b3792; O-antigen translocase 3865220 wzxE 7956117 wzxE Escherichia coli BW2952 O-antigen translocase YP_002928668.1 3863970 D 595496 CDS YP_002928669.1 238902873 7954419 3865217..3866296 1 NC_012759.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 3866296 rffT 7954419 rffT Escherichia coli BW2952 4-alpha-L-fucosyltransferase YP_002928669.1 3865217 D 595496 CDS YP_002928670.1 238902874 7956118 3866293..3867645 1 NC_012759.1 enterobacterial common antigen polymerase; putative common antigen polymerase 3867645 wzyE 7956118 wzyE Escherichia coli BW2952 putative common antigen polymerase YP_002928670.1 3866293 D 595496 CDS YP_002928671.1 238902875 7955751 3867648..3868388 1 NC_012759.1 MG1655 equivalent: b3794; putative UDP-N-acetyl-D-mannosaminuronic acid transferase 3868388 rffM 7955751 rffM Escherichia coli BW2952 putative UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002928671.1 3867648 D 595496 CDS YP_002928672.1 238902876 7956237 3868579..3869964 1 NC_012759.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 3869964 yifK 7956237 yifK Escherichia coli BW2952 putative transport protein YifK YP_002928672.1 3868579 D 595496 CDS YP_002928673.1 238902877 7952154 3870650..3871885 1 NC_012759.1 MG1655 equivalent: b3800; putative regulator of arylsulfatase activity 3871885 aslB 7952154 aslB Escherichia coli BW2952 putative regulator of arylsulfatase activity YP_002928673.1 3870650 D 595496 CDS YP_002928674.1 238902878 7955562 complement(3872044..3873699) 1 NC_012759.1 MG1655 equivalent: b3801; acrylsulfatase-like enzyme 3873699 aslA 7955562 aslA Escherichia coli BW2952 acrylsulfatase-like enzyme YP_002928674.1 3872044 R 595496 CDS YP_002928675.1 238902879 7952198 complement(3874378..3875574) 1 NC_012759.1 MG1655 equivalent: b3802; putative protoheme IX biogenesis protein 3875574 hemY 7952198 hemY Escherichia coli BW2952 putative protoheme IX biogenesis protein YP_002928675.1 3874378 R 595496 CDS YP_002928676.1 238902880 7955547 complement(3875577..3876758) 1 NC_012759.1 MG1655 equivalent: b3803; putative uroporphyrinogen III C-methyltransferase 3876758 hemX 7955547 hemX Escherichia coli BW2952 putative uroporphyrinogen III C-methyltransferase YP_002928676.1 3875577 R 595496 CDS YP_002928677.1 238902881 7955748 complement(3876780..3877520) 1 NC_012759.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 3877520 hemD 7955748 hemD Escherichia coli BW2952 uroporphyrinogen-III synthase YP_002928677.1 3876780 R 595496 CDS YP_002928678.1 238902882 7956268 complement(3877517..3878458) 1 NC_012759.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 3878458 hemC 7956268 hemC Escherichia coli BW2952 porphobilinogen deaminase YP_002928678.1 3877517 R 595496 CDS YP_002928679.1 238902883 7953959 3878845..3881391 1 NC_012759.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 3881391 cyaA 7953959 cyaA Escherichia coli BW2952 adenylate cyclase YP_002928679.1 3878845 D 595496 CDS YP_002928680.1 238902884 7952422 complement(3881431..3881751) 1 NC_012759.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 3881751 cyaY 7952422 cyaY Escherichia coli BW2952 frataxin-like protein YP_002928680.1 3881431 R 595496 CDS YP_002928681.1 238902885 7953631 3882214..3882417 1 NC_012759.1 MG1655 equivalent: b4558; putative lipoprotein 3882417 yifL 7953631 yifL Escherichia coli BW2952 putative lipoprotein YP_002928681.1 3882214 D 595496 CDS YP_002928682.1 238902886 7955119 3882454..3883278 1 NC_012759.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 3883278 dapF 7955119 dapF Escherichia coli BW2952 diaminopimelate epimerase YP_002928682.1 3882454 D 595496 CDS YP_002928683.1 238902887 7953248 3883979..3884875 1 NC_012759.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 3884875 xerC 7953248 xerC Escherichia coli BW2952 site-specific tyrosine recombinase XerC YP_002928683.1 3883979 D 595496 CDS YP_002928684.1 238902888 7956048 3884875..3885591 1 NC_012759.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 3885591 yigB 7956048 yigB Escherichia coli BW2952 flavin mononucleotide phosphatase YP_002928684.1 3884875 D 595496 CDS YP_002928685.1 238902889 7954972 3885675..3887837 1 NC_012759.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 3887837 uvrD 7954972 uvrD Escherichia coli BW2952 DNA-dependent helicase II YP_002928685.1 3885675 D 595496 CDS YP_002928686.1 238902890 7953487 complement(3887984..3888748) 1 NC_012759.1 MG1655 equivalent: b4482; hypothetical protein 3888748 yigE 7953487 yigE Escherichia coli BW2952 hypothetical protein YP_002928686.1 3887984 R 595496 CDS YP_002928687.1 238902891 7955431 3889118..3890068 1 NC_012759.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 3890068 corA 7955431 corA Escherichia coli BW2952 magnesium/nickel/cobalt transporter CorA YP_002928687.1 3889118 D 595496 CDS YP_002928688.1 238902892 7954192 complement(3890111..3890491) 1 NC_012759.1 MG1655 equivalent: b3817; hypothetical protein 3890491 yigF 7954192 yigF Escherichia coli BW2952 hypothetical protein YP_002928688.1 3890111 R 595496 CDS YP_002928689.1 238902893 7952691 complement(3890505..3890885) 1 NC_012759.1 MG1655 equivalent: b3818; hypothetical protein 3890885 yigG 7952691 yigG Escherichia coli BW2952 hypothetical protein YP_002928689.1 3890505 R 595496 CDS YP_002928690.1 238902894 7955015 complement(3890980..3891870) 1 NC_012759.1 MG1655 equivalent: b3819; putative chloramphenical resistance permease 3891870 rarD 7955015 rarD Escherichia coli BW2952 putative chloramphenical resistance permease YP_002928690.1 3890980 R 595496 CDS YP_002928691.1 238902895 7954692 complement(3891922..3892389) 1 NC_012759.1 MG1655 equivalent: b3820; hypothetical protein 3892389 yigI 7954692 yigI Escherichia coli BW2952 hypothetical protein YP_002928691.1 3891922 R 595496 CDS YP_002928692.1 238902896 7952891 3892554..3893423 1 NC_012759.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 3893423 pldA 7952891 pldA Escherichia coli BW2952 phospholipase A YP_002928692.1 3892554 D 595496 CDS YP_002928693.1 238902897 7954441 3893556..3895385 1 NC_012759.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 3895385 recQ 7954441 recQ Escherichia coli BW2952 ATP-dependent DNA helicase RecQ YP_002928693.1 3893556 D 595496 CDS YP_002928694.1 238902898 7952531 3895449..3896069 1 NC_012759.1 MG1655 equivalent: b3823; threonine efflux system 3896069 rhtC 7952531 rhtC Escherichia coli BW2952 threonine efflux system YP_002928694.1 3895449 D 595496 CDS YP_002928695.1 238902899 7956145 complement(3896131..3896751) 1 NC_012759.1 MG1655 equivalent: b3824; homoserine/homoserine lactone efflux protein 3896751 rhtB 7956145 rhtB Escherichia coli BW2952 homoserine/homoserine lactone efflux protein YP_002928695.1 3896131 R 595496 CDS YP_002928696.1 238902900 7954374 3896862..3897884 1 NC_012759.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 3897884 pldB 7954374 pldB Escherichia coli BW2952 lysophospholipase L2 YP_002928696.1 3896862 D 595496 CDS YP_002928697.1 238902901 7954186 3897892..3898692 1 NC_012759.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 3898692 yigL 7954186 yigL Escherichia coli BW2952 putative sugar phosphatase YP_002928697.1 3897892 D 595496 CDS YP_002928698.1 238902902 7954973 3898768..3899667 1 NC_012759.1 MG1655 equivalent: b3827; putative inner membrane protein 3899667 yigM 7954973 yigM Escherichia coli BW2952 putative inner membrane protein YP_002928698.1 3898768 D 595496 CDS YP_002928699.1 238902903 7955072 complement(3899555..3900508) 1 NC_012759.1 MG1655 equivalent: b3828; DNA-binding transcriptional activator, homocysteine-binding 3900508 metR 7955072 metR Escherichia coli BW2952 DNA-binding transcriptional activator, homocysteine-binding YP_002928699.1 3899555 R 595496 CDS YP_002928700.1 238902904 7953397 3900745..3903006 1 NC_012759.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 3903006 metE 7953397 metE Escherichia coli BW2952 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_002928700.1 3900745 D 595496 CDS YP_002928701.1 238902905 7952374 complement(3903046..3903861) 1 NC_012759.1 MG1655 equivalent: b3830; putative hydrolase 3903861 ysgA 7952374 ysgA Escherichia coli BW2952 putative hydrolase YP_002928701.1 3903046 R 595496 CDS YP_002928702.1 238902906 7954962 3904123..3904884 1 NC_012759.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 3904884 udp 7954962 udp Escherichia coli BW2952 uridine phosphorylase YP_002928702.1 3904123 D 595496 CDS YP_002928703.1 238902907 7956262 3905025..3906452 1 NC_012759.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 3906452 rmuC 7956262 rmuC Escherichia coli BW2952 DNA recombination protein RmuC YP_002928703.1 3905025 D 595496 CDS YP_002928704.1 238902908 7955556 3906547..3907302 1 NC_012759.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 3907302 ubiE 7955556 ubiE Escherichia coli BW2952 ubiquinone/menaquinone biosynthesis methyltransferase YP_002928704.1 3906547 D 595496 CDS YP_002928705.1 238902909 7952556 3907316..3907921 1 NC_012759.1 MG1655 equivalent: b3834; hypothetical protein 3907921 yigP 7952556 yigP Escherichia coli BW2952 hypothetical protein YP_002928705.1 3907316 D 595496 CDS YP_002928706.1 238902910 7953041 3907918..3909558 1 NC_012759.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 3909558 ubiB 7953041 ubiB Escherichia coli BW2952 putative ubiquinone biosynthesis protein UbiB YP_002928706.1 3907918 D 595496 CDS YP_002928707.1 238902911 7952266 3909637..3909906 1 NC_012759.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 3909906 tatA 7952266 tatA Escherichia coli BW2952 twin arginine translocase protein A YP_002928707.1 3909637 D 595496 CDS YP_002928708.1 238902912 7956110 3909910..3910425 1 NC_012759.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 3910425 tatB 7956110 tatB Escherichia coli BW2952 sec-independent translocase YP_002928708.1 3909910 D 595496 CDS YP_002928709.1 238902913 7956111 3910428..3911204 1 NC_012759.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 3911204 tatC 7956111 tatC Escherichia coli BW2952 twin-arginine protein translocation system subunit TatC YP_002928709.1 3910428 D 595496 CDS YP_002928710.1 238902914 7956112 3911246..3912028 1 NC_012759.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 3912028 tatD 7956112 tatD Escherichia coli BW2952 DNase TatD YP_002928710.1 3911246 D 595496 CDS YP_002928711.1 238902915 7953491 complement(3912025..3912513) 1 NC_012759.1 MG1655 equivalent: b3842; transcriptional activator RfaH 3912513 rfaH 7953491 rfaH Escherichia coli BW2952 transcriptional activator RfaH YP_002928711.1 3912025 R 595496 CDS YP_002928712.1 238902916 7953402 3912680..3914173 1 NC_012759.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3914173 ubiD 7953402 ubiD Escherichia coli BW2952 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002928712.1 3912680 D 595496 CDS YP_002928713.1 238902917 7952316 3914219..3914920 1 NC_012759.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 3914920 fre 7952316 fre Escherichia coli BW2952 FMN reductase YP_002928713.1 3914219 D 595496 CDS YP_002928714.1 238902918 7953608 complement(3915301..3916464) 1 NC_012759.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 3916464 fadA 7953608 fadA Escherichia coli BW2952 3-ketoacyl-CoA thiolase YP_002928714.1 3915301 R 595496 CDS YP_002928715.1 238902919 7952308 complement(3916474..3918663) 1 NC_012759.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 3918663 fadB 7952308 fadB Escherichia coli BW2952 multifunctional fatty acid oxidation complex subunit alpha YP_002928715.1 3916474 R 595496 CDS YP_002928716.1 238902920 7953650 3918853..3920184 1 NC_012759.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 3920184 pepQ 7953650 pepQ Escherichia coli BW2952 proline dipeptidase YP_002928716.1 3918853 D 595496 CDS YP_002928717.1 238902921 7955768 3920184..3920798 1 NC_012759.1 MG1655 equivalent: b3848; hypothetical protein 3920798 yigZ 7955768 yigZ Escherichia coli BW2952 hypothetical protein YP_002928717.1 3920184 D 595496 CDS YP_002928718.1 238902922 7954832 3920837..3922288 1 NC_012759.1 MG1655 equivalent: b3849; potassium transporter 3922288 trkH 7954832 trkH Escherichia coli BW2952 potassium transporter YP_002928718.1 3920837 D 595496 CDS YP_002928719.1 238902923 7954577 3922300..3922845 1 NC_012759.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 3922845 hemG 7954577 hemG Escherichia coli BW2952 protoporphyrinogen oxidase YP_002928719.1 3922300 D 595496 CDS YP_002928720.1 238902924 7952108 complement(3928598..3929125) 1 NC_012759.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 3929125 mobB 7952108 mobB Escherichia coli BW2952 molybdopterin-guanine dinucleotide biosynthesis protein B YP_002928720.1 3928598 R 595496 CDS YP_002928721.1 238902925 7954294 complement(3929107..3929691) 1 NC_012759.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 3929691 mobA 7954294 mobA Escherichia coli BW2952 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_002928721.1 3929107 R 595496 CDS YP_002928722.1 238902926 7954295 3929761..3930030 1 NC_012759.1 MG1655 equivalent: b3858; hypothetical protein 3930030 yihD 7954295 yihD Escherichia coli BW2952 hypothetical protein YP_002928722.1 3929761 D 595496 CDS YP_002928723.1 238902927 7953042 3930107..3931093 1 NC_012759.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 3931093 rdoA 7953042 rdoA Escherichia coli BW2952 serine/threonine protein kinase YP_002928723.1 3930107 D 595496 CDS YP_002928724.1 238902928 7956141 3931110..3931736 1 NC_012759.1 MG1655 equivalent: b3860; protein disulfide isomerase I 3931736 dsbA 7956141 dsbA Escherichia coli BW2952 protein disulfide isomerase I YP_002928724.1 3931110 D 595496 CDS YP_002928725.1 238902929 7954499 3931891..3933321 1 NC_012759.1 MG1655 equivalent: b3861; hypothetical protein 3933321 yihF 7954499 yihF Escherichia coli BW2952 hypothetical protein YP_002928725.1 3931891 D 595496 CDS YP_002928726.1 238902930 7953043 complement(3933362..3934294) 1 NC_012759.1 MG1655 equivalent: b3862; putative acyltransferase 3934294 yihG 7953043 yihG Escherichia coli BW2952 putative acyltransferase YP_002928726.1 3933362 R 595496 CDS YP_002928727.1 238902931 7954834 3934658..3937444 1 NC_012759.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 3937444 polA 7954834 polA Escherichia coli BW2952 DNA polymerase I YP_002928727.1 3934658 D 595496 CDS YP_002928728.1 238902932 7952199 complement(3937825..3938457) 1 NC_012759.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 3938457 engB 7952199 engB Escherichia coli BW2952 ribosome biogenesis GTP-binding protein YsxC YP_002928728.1 3937825 R 595496 CDS YP_002928729.1 238902933 7952200 3939039..3939548 1 NC_012759.1 MG1655 equivalent: b3866; hypothetical protein 3939548 yihI 7952200 yihI Escherichia coli BW2952 hypothetical protein YP_002928729.1 3939039 D 595496 CDS YP_002928730.1 238902934 7953044 3939737..3941110 1 NC_012759.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3941110 hemN 7953044 hemN Escherichia coli BW2952 coproporphyrinogen III oxidase YP_002928730.1 3939737 D 595496 CDS YP_002928731.1 238902935 7953102 complement(3941561..3942970) 1 NC_012759.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 3942970 glnG 7953102 glnG Escherichia coli BW2952 nitrogen regulation protein NR(I) YP_002928731.1 3941561 R 595496 CDS YP_002928732.1 238902936 7953673 complement(3942982..3944031) 1 NC_012759.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 3944031 glnL 7953673 glnL Escherichia coli BW2952 nitrogen regulation protein NR(II) YP_002928732.1 3942982 R 595496 CDS YP_002928733.1 238902937 7956019 complement(3944317..3945726) 1 NC_012759.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 3945726 glnA 7956019 glnA Escherichia coli BW2952 glutamine synthetase YP_002928733.1 3944317 R 595496 CDS YP_002928734.1 238902938 7953827 3946099..3947922 1 NC_012759.1 MG1655 equivalent: b3871; GTP-binding protein 3947922 typA 7953827 typA Escherichia coli BW2952 GTP-binding protein YP_002928734.1 3946099 D 595496 CDS YP_002928735.1 238902939 7953882 3948139..3948849 1 NC_012759.1 MG1655 equivalent: b3872; putative DNA-binding transcriptional regulator 3948849 yihL 7953882 yihL Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928735.1 3948139 D 595496 CDS YP_002928736.1 238902940 7954816 3948857..3949837 1 NC_012759.1 MG1655 equivalent: b3873; putative sugar phosphate isomerase 3949837 yihM 7954816 yihM Escherichia coli BW2952 putative sugar phosphate isomerase YP_002928736.1 3948857 D 595496 CDS YP_002928737.1 238902941 7955605 3949939..3951204 1 NC_012759.1 MG1655 equivalent: b3874; putative transporter 3951204 yihN 7955605 yihN Escherichia coli BW2952 putative transporter YP_002928737.1 3949939 D 595496 CDS YP_002928738.1 238902942 7955713 complement(3951295..3951987) 1 NC_012759.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L 3951987 ompL 7955713 ompL Escherichia coli BW2952 outer membrane porin L YP_002928738.1 3951295 R 595496 CDS YP_002928739.1 238902943 7955207 complement(3952055..3953458) 1 NC_012759.1 MG1655 equivalent: b3876; putative transporter 3953458 yihO 7955207 yihO Escherichia coli BW2952 putative transporter YP_002928739.1 3952055 R 595496 CDS YP_002928740.1 238902944 7955672 complement(3953501..3954886) 1 NC_012759.1 MG1655 equivalent: b3877; putative transporter 3954886 yihP 7955672 yihP Escherichia coli BW2952 putative transporter YP_002928740.1 3953501 R 595496 CDS YP_002928741.1 238902945 7955673 complement(3954932..3956968) 1 NC_012759.1 MG1655 equivalent: b3878; alpha-glucosidase 3956968 yihQ 7955673 yihQ Escherichia coli BW2952 alpha-glucosidase YP_002928741.1 3954932 R 595496 CDS YP_002928742.1 238902946 7952458 complement(3957167..3958093) 1 NC_012759.1 MG1655 equivalent: b3879; putative aldose-1-epimerase 3958093 yihR 7952458 yihR Escherichia coli BW2952 putative aldose-1-epimerase YP_002928742.1 3957167 R 595496 CDS YP_002928743.1 238902947 7954631 complement(3958207..3959448) 1 NC_012759.1 MG1655 equivalent: b3880; putative glucosamine isomerase 3959448 yihS 7954631 yihS Escherichia coli BW2952 putative glucosamine isomerase YP_002928743.1 3958207 R 595496 CDS YP_002928744.1 238902948 7954919 complement(3959465..3960343) 1 NC_012759.1 MG1655 equivalent: b3881; putative aldolase 3960343 yihT 7954919 yihT Escherichia coli BW2952 putative aldolase YP_002928744.1 3959465 R 595496 CDS YP_002928745.1 238902949 7954630 complement(3960367..3961263) 1 NC_012759.1 MG1655 equivalent: b3882; putative oxidoreductase with NAD(P)-binding Rossmann-fold domain 3961263 yihU 7954630 yihU Escherichia coli BW2952 putative oxidoreductase with NAD(P)-binding Rossmann-fold domain YP_002928745.1 3960367 R 595496 CDS YP_002928746.1 238902950 7955248 3961431..3962327 1 NC_012759.1 MG1655 equivalent: b3883; putative sugar kinase 3962327 yihV 7955248 yihV Escherichia coli BW2952 putative sugar kinase YP_002928746.1 3961431 D 595496 CDS YP_002928747.1 238902951 7955604 3962361..3963146 1 NC_012759.1 MG1655 equivalent: b3884; putative DNA-binding transcriptional regulator 3963146 yihW 7955604 yihW Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928747.1 3962361 D 595496 CDS YP_002928748.1 238902952 7954817 3963245..3963844 1 NC_012759.1 MG1655 equivalent: b3885; phosphatase 3963844 yihX 7954817 yihX Escherichia coli BW2952 phosphatase YP_002928748.1 3963245 D 595496 CDS YP_002928749.1 238902953 7954974 3963838..3964710 1 NC_012759.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 3964710 rbn 7954974 rbn Escherichia coli BW2952 ribonuclease BN YP_002928749.1 3963838 D 595496 CDS YP_002928750.1 238902954 7955073 3964707..3965144 1 NC_012759.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 3965144 dtd 7955073 dtd Escherichia coli BW2952 D-tyrosyl-tRNA(Tyr) deacylase YP_002928750.1 3964707 D 595496 CDS YP_002928751.1 238902955 7953505 3965141..3966130 1 NC_012759.1 MG1655 equivalent: b3888; putative acetyltransferase 3966130 yiiD 7953505 yiiD Escherichia coli BW2952 putative acetyltransferase YP_002928751.1 3965141 D 595496 CDS YP_002928752.1 238902956 7954604 3966989..3967201 1 NC_012759.1 MG1655 equivalent: b3889; putative transcriptional regulator 3967201 yiiE 7954604 yiiE Escherichia coli BW2952 putative transcriptional regulator YP_002928752.1 3966989 D 595496 CDS YP_002928753.1 238902957 7955639 3967443..3967661 1 NC_012759.1 MG1655 equivalent: b3890; hypothetical protein 3967661 yiiF 7955639 yiiF Escherichia coli BW2952 hypothetical protein YP_002928753.1 3967443 D 595496 CDS YP_002928754.1 238902958 7953045 complement(3967991..3968920) 1 NC_012759.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 3968920 fdhE 7953045 fdhE Escherichia coli BW2952 formate dehydrogenase accessory protein FdhE YP_002928754.1 3967991 R 595496 CDS YP_002928755.1 238902959 7953615 complement(3968917..3969552) 1 NC_012759.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 3969552 fdoI 7953615 fdoI Escherichia coli BW2952 formate dehydrogenase-O subunit gamma YP_002928755.1 3968917 R 595496 CDS YP_002928756.1 238902960 7953622 complement(3969549..3970451) 1 NC_012759.1 MG1655 equivalent: b3893; formate dehydrogenase-O, Fe-S subunit 3970451 fdoH 7953622 fdoH Escherichia coli BW2952 formate dehydrogenase-O, Fe-S subunit YP_002928756.1 3969549 R 595496 CDS YP_002928757.1 238902961 7953623 complement(3970464..3973514) 1 NC_012759.1 MG1655 equivalent: b3894; formate dehydrogenase-O, large subunit 3973514 fdoG 7953623 fdoG Escherichia coli BW2952 formate dehydrogenase-O, large subunit YP_002928757.1 3970464 R 595496 CDS YP_002928758.1 238902962 7953624 3973708..3974541 1 NC_012759.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 3974541 fdhD 7953624 fdhD Escherichia coli BW2952 formate dehydrogenase accessory protein YP_002928758.1 3973708 D 595496 CDS YP_002928759.1 238902963 7953616 3974694..3975749 1 NC_012759.1 MG1655 equivalent: b3896; hypothetical protein 3975749 yiiG 7953616 yiiG Escherichia coli BW2952 hypothetical protein YP_002928759.1 3974694 D 595496 CDS YP_002928760.1 238902964 7953046 complement(3975799..3977547) 1 NC_012759.1 putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; putative frv operon regulatory protein 3977547 frvR 7953046 frvR Escherichia coli BW2952 putative frv operon regulatory protein YP_002928760.1 3975799 R 595496 CDS YP_002928761.1 238902965 7955559 complement(3977547..3978617) 1 NC_012759.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; putative fructose-specific phosphotransferase system protein FrvX 3978617 frvX 7955559 frvX Escherichia coli BW2952 putative fructose-specific phosphotransferase system protein FrvX YP_002928761.1 3977547 R 595496 CDS YP_002928762.1 238902966 7954833 complement(3978607..3980058) 1 NC_012759.1 MG1655 equivalent: b3899; putative PTS system transporter subunits IIBC 3980058 frvB 7954833 frvB Escherichia coli BW2952 putative PTS system transporter subunits IIBC YP_002928762.1 3978607 R 595496 CDS YP_002928763.1 238902967 7953725 complement(3980069..3980515) 1 NC_012759.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; putative fructose-like phosphotransferase system subunit EIIA 3980515 frvA 7953725 frvA Escherichia coli BW2952 putative fructose-like phosphotransferase system subunit EIIA YP_002928763.1 3980069 R 595496 CDS YP_002928764.1 238902968 7954851 complement(3980816..3981130) 1 NC_012759.1 MG1655 equivalent: b3901; L-rhamnose mutarotase 3981130 rhaM 7954851 rhaM Escherichia coli BW2952 L-rhamnose mutarotase YP_002928764.1 3980816 R 595496 CDS YP_002928765.1 238902969 7954165 complement(3981140..3981964) 1 NC_012759.1 MG1655 equivalent: b3902; rhamnulose-1-phosphate aldolase 3981964 rhaD 7954165 rhaD Escherichia coli BW2952 rhamnulose-1-phosphate aldolase YP_002928765.1 3981140 R 595496 CDS YP_002928766.1 238902970 7955947 complement(3982415..3983674) 1 NC_012759.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 3983674 rhaA 7955947 rhaA Escherichia coli BW2952 L-rhamnose isomerase YP_002928766.1 3982415 R 595496 CDS YP_002928767.1 238902971 7954164 complement(3983671..3985140) 1 NC_012759.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 3985140 rhaB 7954164 rhaB Escherichia coli BW2952 rhamnulokinase YP_002928767.1 3983671 R 595496 CDS YP_002928768.1 238902972 7955946 3985428..3986264 1 NC_012759.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 3986264 rhaS 7955946 rhaS Escherichia coli BW2952 transcriptional activator RhaS YP_002928768.1 3985428 D 595496 CDS YP_002928769.1 238902973 7953398 3986338..3987186 1 NC_012759.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 3987186 rhaR 7953398 rhaR Escherichia coli BW2952 transcriptional activator RhaR YP_002928769.1 3986338 D 595496 CDS YP_002928770.1 238902974 7953399 complement(3987183..3988217) 1 NC_012759.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 3988217 rhaT 7953399 rhaT Escherichia coli BW2952 rhamnose-proton symporter YP_002928770.1 3987183 R 595496 CDS YP_002928771.1 238902975 7954166 3988502..3989122 1 NC_012759.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 3989122 sodA 7954166 sodA Escherichia coli BW2952 superoxide dismutase YP_002928771.1 3988502 D 595496 CDS YP_002928772.1 238902976 7956101 3989382..3990365 1 NC_012759.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 3990365 kdgT 7956101 kdgT Escherichia coli BW2952 2-keto-3-deoxygluconate permease YP_002928772.1 3989382 D 595496 CDS YP_002928773.1 238902977 7952260 3990514..3991188 1 NC_012759.1 MG1655 equivalent: b3910; hypothetical protein 3991188 yiiM 7952260 yiiM Escherichia coli BW2952 hypothetical protein YP_002928773.1 3990514 D 595496 CDS YP_002928774.1 238902978 7953047 complement(3991294..3992667) 1 NC_012759.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 3992667 cpxA 7953047 cpxA Escherichia coli BW2952 two-component sensor protein YP_002928774.1 3991294 R 595496 CDS YP_002928775.1 238902979 7956015 complement(3992664..3993362) 1 NC_012759.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 3993362 cpxR 7956015 cpxR Escherichia coli BW2952 DNA-binding transcriptional regulator CpxR YP_002928775.1 3992664 R 595496 CDS YP_002928776.1 238902980 7953348 3993512..3994012 1 NC_012759.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 3994012 cpxP 7953348 cpxP Escherichia coli BW2952 repressor CpxP YP_002928776.1 3993512 D 595496 CDS YP_002928777.1 238902981 7954498 3994161..3995063 1 NC_012759.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 3995063 fieF 7954498 fieF Escherichia coli BW2952 ferrous iron efflux protein F YP_002928777.1 3994161 D 595496 CDS YP_002928778.1 238902982 7956285 3995244..3996206 1 NC_012759.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3996206 pfkA 7956285 pfkA Escherichia coli BW2952 6-phosphofructokinase YP_002928778.1 3995244 D 595496 CDS YP_002928779.1 238902983 7952377 3996526..3997515 1 NC_012759.1 MG1655 equivalent: b3917; sulfate transporter subunit 3997515 sbp 7952377 sbp Escherichia coli BW2952 sulfate transporter subunit YP_002928779.1 3996526 D 595496 CDS YP_002928780.1 238902984 7956090 3997622..3998377 1 NC_012759.1 MG1655 equivalent: b3918; CDP-diacylglycerol pyrophosphatase 3998377 cdh 7956090 cdh Escherichia coli BW2952 CDP-diacylglycerol pyrophosphatase YP_002928780.1 3997622 D 595496 CDS YP_002928781.1 238902985 7952612 complement(3998432..3999199) 1 NC_012759.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3999199 tpiA 7952612 tpiA Escherichia coli BW2952 triosephosphate isomerase YP_002928781.1 3998432 R 595496 CDS YP_002928782.1 238902986 7956193 complement(3999307..3999906) 1 NC_012759.1 MG1655 equivalent: b3920; hypothetical protein 3999906 yiiQ 7956193 yiiQ Escherichia coli BW2952 hypothetical protein YP_002928782.1 3999307 R 595496 CDS YP_002928783.1 238902987 7952892 4000007..4000447 1 NC_012759.1 MG1655 equivalent: b3921; hypothetical protein 4000447 yiiR 7952892 yiiR Escherichia coli BW2952 hypothetical protein YP_002928783.1 4000007 D 595496 CDS YP_002928784.1 238902988 7952732 4000659..4000958 1 NC_012759.1 MG1655 equivalent: b3922; hypothetical protein 4000958 yiiS 7952732 yiiS Escherichia coli BW2952 hypothetical protein YP_002928784.1 4000659 D 595496 CDS YP_002928785.1 238902989 7953048 4000985..4001413 1 NC_012759.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4001413 uspD 7953048 uspD Escherichia coli BW2952 universal stress protein UspD YP_002928785.1 4000985 D 595496 CDS YP_002928786.1 238902990 7956073 complement(4001418..4002164) 1 NC_012759.1 MG1655 equivalent: b3924; ferredoxin-NADP reductase 4002164 fpr 7956073 fpr Escherichia coli BW2952 ferredoxin-NADP reductase YP_002928786.1 4001418 R 595496 CDS YP_002928787.1 238902991 7953564 complement(4002261..4003271) 1 NC_012759.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4003271 glpX 7953564 glpX Escherichia coli BW2952 fructose 1,6-bisphosphatase II YP_002928787.1 4002261 R 595496 CDS YP_002928788.1 238902992 7953633 complement(4003406..4004914) 1 NC_012759.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4004914 glpK 7953633 glpK Escherichia coli BW2952 glycerol kinase YP_002928788.1 4003406 R 595496 CDS YP_002928789.1 238902993 7953847 complement(4004937..4005782) 1 NC_012759.1 MG1655 equivalent: b3927; glycerol facilitator 4005782 glpF 7953847 glpF Escherichia coli BW2952 glycerol facilitator YP_002928789.1 4004937 R 595496 CDS YP_002928790.1 238902994 7953846 4006207..4006452 1 NC_012759.1 MG1655 equivalent: b3928; hypothetical protein 4006452 yiiU 7953846 yiiU Escherichia coli BW2952 hypothetical protein YP_002928790.1 4006207 D 595496 CDS YP_002928791.1 238902995 7953049 complement(4006537..4007022) 1 NC_012759.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4007022 rraA 7953049 rraA Escherichia coli BW2952 ribonuclease activity regulator protein RraA YP_002928791.1 4006537 R 595496 CDS YP_002928792.1 238902996 7955957 complement(4007115..4008041) 1 NC_012759.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4008041 menA 7955957 menA Escherichia coli BW2952 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002928792.1 4007115 R 595496 CDS YP_002928793.1 238902997 7952220 complement(4008108..4009439) 1 NC_012759.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4009439 hslU 7952220 hslU Escherichia coli BW2952 ATP-dependent protease ATP-binding subunit HslU YP_002928793.1 4008108 R 595496 CDS YP_002928794.1 238902998 7954281 complement(4009449..4009979) 1 NC_012759.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4009979 hslV 7954281 hslV Escherichia coli BW2952 ATP-dependent protease peptidase subunit YP_002928794.1 4009449 R 595496 CDS YP_002928795.1 238902999 7954472 complement(4010072..4011031) 1 NC_012759.1 MG1655 equivalent: b3933; essential cell division protein FtsN 4011031 ftsN 7954472 ftsN Escherichia coli BW2952 essential cell division protein FtsN YP_002928795.1 4010072 R 595496 CDS YP_002928796.1 238903000 7953532 complement(4011123..4012148) 1 NC_012759.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4012148 cytR 7953532 cytR Escherichia coli BW2952 DNA-binding transcriptional regulator CytR YP_002928796.1 4011123 R 595496 CDS YP_002928797.1 238903001 7953414 complement(4012304..4014502) 1 NC_012759.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4014502 priA 7953414 priA Escherichia coli BW2952 primosome assembly protein PriA YP_002928797.1 4012304 R 595496 CDS YP_002928798.1 238903002 7955766 4014705..4014917 1 NC_012759.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4014917 rpmE 7955766 rpmE Escherichia coli BW2952 50S ribosomal protein L31 YP_002928798.1 4014705 D 595496 CDS YP_002928799.1 238903003 7952359 complement(4014978..4015586) 1 NC_012759.1 member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase 4015586 yiiX 7952359 yiiX Escherichia coli BW2952 putative peptidoglycan peptidase YP_002928799.1 4014978 R 595496 CDS YP_002928800.1 238903004 7955296 complement(4015770..4016087) 1 NC_012759.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4016087 metJ 7955296 metJ Escherichia coli BW2952 transcriptional repressor protein MetJ YP_002928800.1 4015770 R 595496 CDS YP_002928801.1 238903005 7953481 4016364..4017524 1 NC_012759.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4017524 metB 7953481 metB Escherichia coli BW2952 cystathionine gamma-synthase YP_002928801.1 4016364 D 595496 CDS YP_002928802.1 238903006 7953180 4017527..4019959 1 NC_012759.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4019959 metL 7953180 metL Escherichia coli BW2952 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_002928802.1 4017527 D 595496 CDS YP_002928803.1 238903007 7953658 4020308..4021198 1 NC_012759.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4021198 metF 7953658 metF Escherichia coli BW2952 5,10-methylenetetrahydrofolate reductase YP_002928803.1 4020308 D 595496 CDS YP_002928804.1 238903008 7952336 4021527..4023707 1 NC_012759.1 MG1655 equivalent: b3942; catalase/hydroperoxidase HPI(I) 4023707 katG 7952336 katG Escherichia coli BW2952 catalase/hydroperoxidase HPI(I) YP_002928804.1 4021527 D 595496 CDS YP_002928805.1 238903009 7952611 4023800..4024705 1 NC_012759.1 MG1655 equivalent: b3943; putative permease 4024705 yijE 7952611 yijE Escherichia coli BW2952 putative permease YP_002928805.1 4023800 D 595496 CDS YP_002928806.1 238903010 7955308 complement(4024732..4025349) 1 NC_012759.1 MG1655 equivalent: b3944; hypothetical protein 4025349 yijF 7955308 yijF Escherichia coli BW2952 hypothetical protein YP_002928806.1 4024732 R 595496 CDS YP_002928807.1 238903011 7952893 complement(4025624..4026727) 1 NC_012759.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4026727 gldA 7952893 gldA Escherichia coli BW2952 glycerol dehydrogenase YP_002928807.1 4025624 R 595496 CDS YP_002928808.1 238903012 7953845 complement(4026738..4027400) 1 NC_012759.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4027400 fsaB 7953845 fsaB Escherichia coli BW2952 fructose-6-phosphate aldolase YP_002928808.1 4026738 R 595496 CDS YP_002928809.1 238903013 7953636 complement(4027412..4029913) 1 NC_012759.1 MG1655 equivalent: b3947; fused putative PTS enzymes: Hpr component/enzyme I component/enzyme IIA component 4029913 ptsA 7953636 ptsA Escherichia coli BW2952 fused putative PTS enzymes: Hpr component/enzyme I component/enzyme IIA component YP_002928809.1 4027412 R 595496 CDS YP_002928810.1 238903014 7953724 4030222..4031301 1 NC_012759.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative fructose-like permease EIIC subunit 2 4031301 frwC 7953724 frwC Escherichia coli BW2952 putative fructose-like permease EIIC subunit 2 YP_002928810.1 4030222 D 595496 CDS YP_002928811.1 238903015 7954857 4031316..4031636 1 NC_012759.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4031636 frwB 7954857 frwB Escherichia coli BW2952 putative PTS system fructose-like transporter subunit EIIB YP_002928811.1 4031316 D 595496 CDS YP_002928812.1 238903016 7954854 4031687..4033984 1 NC_012759.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4033984 pflD 7954854 pflD Escherichia coli BW2952 putative formate acetyltransferase 2 YP_002928812.1 4031687 D 595496 CDS YP_002928813.1 238903017 7954910 4033950..4034828 1 NC_012759.1 MG1655 equivalent: b3952; pyruvate formate lyase II activase 4034828 pflC 7954910 pflC Escherichia coli BW2952 pyruvate formate lyase II activase YP_002928813.1 4033950 D 595496 CDS YP_002928814.1 238903018 7955849 4034830..4035171 1 NC_012759.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative fructose-like phosphotransferase EIIB subunit 3 4035171 frwD 7955849 frwD Escherichia coli BW2952 putative fructose-like phosphotransferase EIIB subunit 3 YP_002928814.1 4034830 D 595496 CDS YP_002928815.1 238903019 7954855 complement(4035158..4036009) 1 NC_012759.1 MG1655 equivalent: b3954; putative DNA-binding transcriptional regulator 4036009 yijO 7954855 yijO Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002928815.1 4035158 R 595496 CDS YP_002928816.1 238903020 7954785 complement(4036224..4037957) 1 NC_012759.1 MG1655 equivalent: b3955; hypothetical protein 4037957 yijP 7954785 yijP Escherichia coli BW2952 hypothetical protein YP_002928816.1 4036224 R 595496 CDS YP_002928817.1 238903021 7952692 complement(4038139..4040790) 1 NC_012759.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4040790 ppc 7952692 ppc Escherichia coli BW2952 phosphoenolpyruvate carboxylase YP_002928817.1 4038139 R 595496 CDS YP_002928818.1 238903022 7954529 complement(4041388..4042539) 1 NC_012759.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4042539 argE 7954529 argE Escherichia coli BW2952 acetylornithine deacetylase YP_002928818.1 4041388 R 595496 CDS YP_002928819.1 238903023 7952406 4042693..4043697 1 NC_012759.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4043697 argC 7952406 argC Escherichia coli BW2952 N-acetyl-gamma-glutamyl-phosphate reductase YP_002928819.1 4042693 D 595496 CDS YP_002928820.1 238903024 7954340 4043705..4044481 1 NC_012759.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4044481 argB 7954340 argB Escherichia coli BW2952 acetylglutamate kinase YP_002928820.1 4043705 D 595496 CDS YP_002928821.1 238903025 7952405 4044542..4045915 1 NC_012759.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4045915 argH 7952405 argH Escherichia coli BW2952 argininosuccinate lyase YP_002928821.1 4044542 D 595496 CDS YP_002928822.1 238903026 7952098 4046182..4047099 1 NC_012759.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4047099 oxyR 7952098 oxyR Escherichia coli BW2952 DNA-binding transcriptional regulator OxyR YP_002928822.1 4046182 D 595496 CDS YP_002928823.1 238903027 7953424 complement(4047082..4048482) 1 NC_012759.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4048482 sthA 7953424 sthA Escherichia coli BW2952 soluble pyridine nucleotide transhydrogenase YP_002928823.1 4047082 R 595496 CDS YP_002928824.1 238903028 7955837 4048816..4049463 1 NC_012759.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4049463 fabR 7955837 fabR Escherichia coli BW2952 DNA-binding transcriptional repressor FabR YP_002928824.1 4048816 D 595496 CDS YP_002928825.1 238903029 7953470 4049463..4049822 1 NC_012759.1 MG1655 equivalent: b3964; hypothetical protein 4049822 yijD 7953470 yijD Escherichia coli BW2952 hypothetical protein YP_002928825.1 4049463 D 595496 CDS YP_002928826.1 238903030 7952733 complement(4049862..4050962) 1 NC_012759.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4050962 trmA 7952733 trmA Escherichia coli BW2952 tRNA (uracil-5-)-methyltransferase YP_002928826.1 4049862 R 595496 CDS YP_002928827.1 238903031 7956199 4051331..4053175 1 NC_012759.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4053175 btuB 7956199 btuB Escherichia coli BW2952 vitamin B12/cobalamin outer membrane transporter YP_002928827.1 4051331 D 595496 CDS YP_002928828.1 238903032 7956274 4053120..4053977 1 NC_012759.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4053977 murI 7956274 murI Escherichia coli BW2952 glutamate racemase YP_002928828.1 4053120 D 595496 CDS YP_002928829.1 238903033 7952111 4059760..4060788 1 NC_012759.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4060788 murB 7952111 murB Escherichia coli BW2952 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002928829.1 4059760 D 595496 CDS YP_002928830.1 238903034 7956238 4060785..4061750 1 NC_012759.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4061750 birA 7956238 birA Escherichia coli BW2952 biotin--protein ligase YP_002928830.1 4060785 D 595496 CDS YP_002928831.1 238903035 7952563 complement(4061779..4062729) 1 NC_012759.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4062729 coaA 7952563 coaA Escherichia coli BW2952 pantothenate kinase YP_002928831.1 4061779 R 595496 CDS YP_002928832.1 238903036 7952161 4063647..4064831 1 NC_012759.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4064831 tufB 7952161 tufB Escherichia coli BW2952 elongation factor Tu YP_002928832.1 4063647 D 595496 CDS YP_002928833.1 238903037 7955787 4065061..4065444 1 NC_012759.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4065444 secE 7955787 secE Escherichia coli BW2952 preprotein translocase subunit SecE YP_002928833.1 4065061 D 595496 CDS YP_002928834.1 238903038 7955762 4065446..4065991 1 NC_012759.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4065991 nusG 7955762 nusG Escherichia coli BW2952 transcription antitermination protein NusG YP_002928834.1 4065446 D 595496 CDS YP_002928835.1 238903039 7956170 4066150..4066578 1 NC_012759.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4066578 rplK 7956170 rplK Escherichia coli BW2952 50S ribosomal protein L11 YP_002928835.1 4066150 D 595496 CDS YP_002928836.1 238903040 7952339 4066582..4067286 1 NC_012759.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4067286 rplA 7952339 rplA Escherichia coli BW2952 50S ribosomal protein L1 YP_002928836.1 4066582 D 595496 CDS YP_002928837.1 238903041 7952337 4067699..4068196 1 NC_012759.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4068196 rplJ 7952337 rplJ Escherichia coli BW2952 50S ribosomal protein L10 YP_002928837.1 4067699 D 595496 CDS YP_002928838.1 238903042 7952338 4068263..4068628 1 NC_012759.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4068628 rplL 7952338 rplL Escherichia coli BW2952 50S ribosomal protein L7/L12 YP_002928838.1 4068263 D 595496 CDS YP_002928839.1 238903043 7952368 4068948..4072976 1 NC_012759.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4072976 rpoB 7952368 rpoB Escherichia coli BW2952 DNA-directed RNA polymerase subunit beta YP_002928839.1 4068948 D 595496 CDS YP_002928840.1 238903044 7955985 4073053..4077276 1 NC_012759.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4077276 rpoC 7955985 rpoC Escherichia coli BW2952 DNA-directed RNA polymerase subunit beta' YP_002928840.1 4073053 D 595496 CDS YP_002928841.1 238903045 7955984 4077489..4078028 1 NC_012759.1 MG1655 equivalent: b3989; heat shock protein 4078028 yjaZ 7955984 yjaZ Escherichia coli BW2952 heat shock protein YP_002928841.1 4077489 D 595496 CDS YP_002928842.1 238903046 7953893 complement(4078438..4079571) 1 NC_012759.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4079571 thiH 7953893 thiH Escherichia coli BW2952 thiamine biosynthesis protein ThiH YP_002928842.1 4078438 R 595496 CDS YP_002928843.1 238903047 7956124 complement(4079568..4080338) 1 NC_012759.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4080338 thiG 7956124 thiG Escherichia coli BW2952 thiazole synthase YP_002928843.1 4079568 R 595496 CDS YP_002928844.1 238903048 7956125 complement(4080340..4080540) 1 NC_012759.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4080540 thiS 7956125 thiS Escherichia coli BW2952 sulfur carrier protein ThiS YP_002928844.1 4080340 R 595496 CDS YP_002928845.1 238903049 7956098 complement(4080524..4081279) 1 NC_012759.1 MG1655 equivalent: b3992; thiamin (thiazole moiety) biosynthesis protein 4081279 thiF 7956098 thiF Escherichia coli BW2952 thiamin (thiazole moiety) biosynthesis protein YP_002928845.1 4080524 R 595496 CDS YP_002928846.1 238903050 7956123 complement(4081272..4081907) 1 NC_012759.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4081907 thiE 7956123 thiE Escherichia coli BW2952 thiamine-phosphate pyrophosphorylase YP_002928846.1 4081272 R 595496 CDS YP_002928847.1 238903051 7956128 complement(4081907..4083802) 1 NC_012759.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4083802 thiC 7956128 thiC Escherichia coli BW2952 thiamine biosynthesis protein ThiC YP_002928847.1 4081907 R 595496 CDS YP_002928848.1 238903052 7956122 complement(4084035..4084511) 1 NC_012759.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4084511 rsd 7956122 rsd Escherichia coli BW2952 anti-RNA polymerase sigma 70 factor YP_002928848.1 4084035 R 595496 CDS YP_002928849.1 238903053 7956067 4084606..4085379 1 NC_012759.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4085379 nudC 7956067 nudC Escherichia coli BW2952 NADH pyrophosphatase YP_002928849.1 4084606 D 595496 CDS YP_002928850.1 238903054 7954354 4085419..4086483 1 NC_012759.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4086483 hemE 7954354 hemE Escherichia coli BW2952 uroporphyrinogen decarboxylase YP_002928850.1 4085419 D 595496 CDS YP_002928851.1 238903055 7956267 4086493..4087164 1 NC_012759.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4087164 nfi 7956267 nfi Escherichia coli BW2952 endonuclease V YP_002928851.1 4086493 D 595496 CDS YP_002928852.1 238903056 7953520 4087207..4087797 1 NC_012759.1 MG1655 equivalent: b3999; hypothetical protein 4087797 yjaG 7953520 yjaG Escherichia coli BW2952 hypothetical protein YP_002928852.1 4087207 D 595496 CDS YP_002928853.1 238903057 7953050 4087984..4088256 1 NC_012759.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4088256 hupA 7953050 hupA Escherichia coli BW2952 transcriptional regulator HU subunit alpha YP_002928853.1 4087984 D 595496 CDS YP_002928854.1 238903058 7953926 4088269..4088964 1 NC_012759.1 MG1655 equivalent: b4001; hypothetical protein 4088964 yjaH 7953926 yjaH Escherichia coli BW2952 hypothetical protein YP_002928854.1 4088269 D 595496 CDS YP_002928855.1 238903059 7953051 complement(4088966..4089391) 1 NC_012759.1 MG1655 equivalent: b4002; zinc resistance protein 4089391 zraP 7953051 zraP Escherichia coli BW2952 zinc resistance protein YP_002928855.1 4088966 R 595496 CDS YP_002928856.1 238903060 7956290 4089629..4091026 1 NC_012759.1 MG1655 equivalent: b4003; sensor protein ZraS 4091026 zraS 7956290 zraS Escherichia coli BW2952 sensor protein ZraS YP_002928856.1 4089629 D 595496 CDS YP_002928857.1 238903061 7956026 4091023..4092348 1 NC_012759.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4092348 zraR 7956026 zraR Escherichia coli BW2952 transcriptional regulatory protein ZraR YP_002928857.1 4091023 D 595496 CDS YP_002928858.1 238903062 7953674 complement(4092345..4093634) 1 NC_012759.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4093634 purD 7953674 purD Escherichia coli BW2952 phosphoribosylamine--glycine ligase YP_002928858.1 4092345 R 595496 CDS YP_002928859.1 238903063 7954553 complement(4093646..4095235) 1 NC_012759.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4095235 purH 7954553 purH Escherichia coli BW2952 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002928859.1 4093646 R 595496 CDS YP_002928860.1 238903064 7952114 4100937..4101320 1 NC_012759.1 MG1655 equivalent: b4011; hypothetical protein 4101320 yjaA 7952114 yjaA Escherichia coli BW2952 hypothetical protein YP_002928860.1 4100937 D 595496 CDS YP_002928861.1 238903065 7953052 complement(4101383..4101826) 1 NC_012759.1 MG1655 equivalent: b4012; hypothetical protein 4101826 yjaB 7953052 yjaB Escherichia coli BW2952 hypothetical protein YP_002928861.1 4101383 R 595496 CDS YP_002928862.1 238903066 7954601 4101983..4102912 1 NC_012759.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4102912 metA 7954601 metA Escherichia coli BW2952 homoserine O-succinyltransferase YP_002928862.1 4101983 D 595496 CDS YP_002928863.1 238903067 7953920 4103181..4104782 1 NC_012759.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4104782 aceB 7953920 aceB Escherichia coli BW2952 malate synthase YP_002928863.1 4103181 D 595496 CDS YP_002928864.1 238903068 7954200 4104812..4106116 1 NC_012759.1 MG1655 equivalent: b4015; isocitrate lyase 4106116 aceA 7954200 aceA Escherichia coli BW2952 isocitrate lyase YP_002928864.1 4104812 D 595496 CDS YP_002928865.1 238903069 7954052 4106299..4108035 1 NC_012759.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4108035 aceK 7954052 aceK Escherichia coli BW2952 bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_002928865.1 4106299 D 595496 CDS YP_002928866.1 238903070 7954051 complement(4108004..4110190) 1 NC_012759.1 MG1655 equivalent: b4017; ankyrin 4110190 arpA 7954051 arpA Escherichia coli BW2952 ankyrin YP_002928866.1 4108004 R 595496 CDS YP_002928867.1 238903071 7952480 complement(4110507..4111331) 1 NC_012759.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4111331 iclR 7952480 iclR Escherichia coli BW2952 IclR family transcriptional regulator YP_002928867.1 4110507 R 595496 CDS YP_002928868.1 238903072 7953458 4111531..4115214 1 NC_012759.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4115214 metH 7953458 metH Escherichia coli BW2952 B12-dependent methionine synthase YP_002928868.1 4111531 D 595496 CDS YP_002928869.1 238903073 7953918 4115434..4117065 1 NC_012759.1 MG1655 equivalent: b4020; putative transporter 4117065 yjbB 7953918 yjbB Escherichia coli BW2952 putative transporter YP_002928869.1 4115434 D 595496 CDS YP_002928870.1 238903074 7955714 complement(4117156..4117845) 1 NC_012759.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4117845 pepE 7955714 pepE Escherichia coli BW2952 peptidase E YP_002928870.1 4117156 R 595496 CDS YP_002928871.1 238903075 7952215 4118057..4118929 1 NC_012759.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4118929 rluF 7952215 rluF Escherichia coli BW2952 23S rRNA pseudouridine synthase F YP_002928871.1 4118057 D 595496 CDS YP_002928872.1 238903076 7952248 complement(4119062..4119334) 1 NC_012759.1 MG1655 equivalent: b4023; hypothetical protein 4119334 pagB 7952248 pagB Escherichia coli BW2952 hypothetical protein YP_002928872.1 4119062 R 595496 CDS YP_002928873.1 238903077 7952894 complement(4119587..4120936) 1 NC_012759.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4120936 lysC 7952894 lysC Escherichia coli BW2952 aspartate kinase III YP_002928873.1 4119587 R 595496 CDS YP_002928874.1 238903078 7952516 4121461..4123110 1 NC_012759.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4123110 pgi 7952516 pgi Escherichia coli BW2952 glucose-6-phosphate isomerase YP_002928874.1 4121461 D 595496 CDS YP_002928875.1 238903079 7953811 4123609..4123851 1 NC_012759.1 MG1655 equivalent: b4026; hypothetical protein 4123851 yjbE 7953811 yjbE Escherichia coli BW2952 hypothetical protein YP_002928875.1 4123609 D 595496 CDS YP_002928876.1 238903080 7955519 4123965..4124603 1 NC_012759.1 MG1655 equivalent: b4027; putative lipoprotein 4124603 yjbF 7955519 yjbF Escherichia coli BW2952 putative lipoprotein YP_002928876.1 4123965 D 595496 CDS YP_002928877.1 238903081 7955118 4124600..4125337 1 NC_012759.1 MG1655 equivalent: b4028; hypothetical protein 4125337 yjbG 7955118 yjbG Escherichia coli BW2952 hypothetical protein YP_002928877.1 4124600 D 595496 CDS YP_002928878.1 238903082 7953053 4125337..4127433 1 NC_012759.1 MG1655 equivalent: b4029; putative porin 4127433 yjbH 7953053 yjbH Escherichia coli BW2952 putative porin YP_002928878.1 4125337 D 595496 CDS YP_002928879.1 238903083 7955327 complement(4127480..4127758) 1 NC_012759.1 MG1655 equivalent: b4620; hypothetical protein 4127758 yjbT 7955327 yjbT Escherichia coli BW2952 hypothetical protein YP_002928879.1 4127480 R 595496 CDS YP_002928880.1 238903084 7953985 4128028..4128438 1 NC_012759.1 MG1655 equivalent: b4030; phosphate-starvation-inducible protein PsiE 4128438 psiE 7953985 psiE Escherichia coli BW2952 phosphate-starvation-inducible protein PsiE YP_002928880.1 4128028 D 595496 CDS YP_002928881.1 238903085 7955313 complement(4128482..4129957) 1 NC_012759.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 4129957 xylE 7955313 xylE Escherichia coli BW2952 D-xylose transporter XylE YP_002928881.1 4128482 R 595496 CDS YP_002928882.1 238903086 7953508 complement(4130329..4131300) 1 NC_012759.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4131300 malG 7953508 malG Escherichia coli BW2952 maltose transporter permease YP_002928882.1 4130329 R 595496 CDS YP_002928883.1 238903087 7956299 complement(4131538..4132128) 1 NC_012759.1 Repressor protein CI 4132128 7956299 BWG_3689 Escherichia coli BW2952 Repressor protein CI YP_002928883.1 4131538 R 595496 CDS YP_002928884.1 238903088 7955940 4132527..4133786 1 NC_012759.1 Transposase 4133786 7955940 BWG_3690 Escherichia coli BW2952 Transposase YP_002928884.1 4132527 D 595496 CDS YP_002928885.1 238903089 7956181 4133862..4134518 1 NC_012759.1 Transposase 4134518 7956181 BWG_3691 Escherichia coli BW2952 Transposase YP_002928885.1 4133862 D 595496 CDS YP_002928886.1 238903090 7956182 complement(4135063..4135245) 1 NC_012759.1 hypothetical protein 4135245 7956182 BWG_3692 Escherichia coli BW2952 hypothetical protein YP_002928886.1 4135063 R 595496 CDS YP_002928887.1 238903091 7953961 complement(4135356..4135469) 1 NC_012759.1 Xis 4135469 7953961 BWG_3693 Escherichia coli BW2952 Xis YP_002928887.1 4135356 R 595496 CDS YP_002928888.1 238903092 7956280 complement(4135699..4136379) 1 NC_012759.1 Exonuclease 4136379 7956280 BWG_3694 Escherichia coli BW2952 Exonuclease YP_002928888.1 4135699 R 595496 CDS YP_002928889.1 238903093 7953538 complement(4136376..4137161) 1 NC_012759.1 Recombination protein bet 4137161 7953538 BWG_3695 Escherichia coli BW2952 Recombination protein bet YP_002928889.1 4136376 R 595496 CDS YP_002928890.1 238903094 7955917 complement(4137167..4137463) 1 NC_012759.1 Host-nuclease inhibitor protein gam 4137463 7955917 BWG_3696 Escherichia coli BW2952 Host-nuclease inhibitor protein gam YP_002928890.1 4137167 R 595496 CDS YP_002928891.1 238903095 7953922 complement(4137538..4137681) 1 NC_012759.1 Protein kil 4137681 7953922 BWG_3697 Escherichia coli BW2952 Protein kil YP_002928891.1 4137538 R 595496 CDS YP_002928892.1 238903096 7955800 complement(4138158..4138919) 1 NC_012759.1 Aminoglucoside phosphotransferase derived originally from Tn903 4138919 7955800 BWG_3698 Escherichia coli BW2952 Aminoglucoside phosphotransferase derived originally from Tn903 YP_002928892.1 4138158 R 595496 CDS YP_002928893.1 238903097 7952467 complement(4139137..4139505) 1 NC_012759.1 Lambda prophage-derived protein ea10 4139505 7952467 BWG_3699 Escherichia coli BW2952 Lambda prophage-derived protein ea10 YP_002928893.1 4139137 R 595496 CDS YP_002928894.1 238903098 7954114 complement(4139688..4139810) 1 NC_012759.1 Lambda ant-restriction protein 4139810 7954114 BWG_3700 Escherichia coli BW2952 Lambda ant-restriction protein YP_002928894.1 4139688 R 595496 CDS YP_002928895.1 238903099 7954111 complement(4140638..4140961) 1 NC_012759.1 Lambda genome from map unit 74 backward to map unit 67 4140961 7954111 BWG_3701 Escherichia coli BW2952 Lambda genome from map unit 74 backward to map unit 67 YP_002928895.1 4140638 R 595496 CDS YP_002928896.1 238903100 7954112 complement(4141876..4142715) 1 NC_012759.1 Protein rexA 4142715 7954112 BWG_3702 Escherichia coli BW2952 Protein rexA YP_002928896.1 4141876 R 595496 CDS YP_002928897.1 238903101 7955807 complement(4142828..4143541) 1 NC_012759.1 Repressor protein CI 4143541 7955807 BWG_3703 Escherichia coli BW2952 Repressor protein CI YP_002928897.1 4142828 R 595496 CDS YP_002928898.1 238903102 7955941 4143642..4143842 1 NC_012759.1 Regulatory protein cro 4143842 7955941 BWG_3704 Escherichia coli BW2952 Regulatory protein cro YP_002928898.1 4143642 D 595496 CDS YP_002928899.1 238903103 7955929 4144117..4144254 1 NC_012759.1 Phage regulatory protein 4144254 7955929 BWG_3705 Escherichia coli BW2952 Phage regulatory protein YP_002928899.1 4144117 D 595496 CDS YP_002928900.1 238903104 7954503 4144287..4145186 1 NC_012759.1 Replication protein O 4145186 7954503 BWG_3706 Escherichia coli BW2952 Replication protein O YP_002928900.1 4144287 D 595496 CDS YP_002928901.1 238903105 7955937 4145183..4145884 1 NC_012759.1 Replication protein P 4145884 7955937 BWG_3707 Escherichia coli BW2952 Replication protein P YP_002928901.1 4145183 D 595496 CDS YP_002928902.1 238903106 7955938 4146245..4146685 1 NC_012759.1 Protein ninB 4146685 7955938 BWG_3708 Escherichia coli BW2952 Protein ninB YP_002928902.1 4146245 D 595496 CDS YP_002928903.1 238903107 7955801 4146664..4147554 1 NC_012759.1 Nin-like protein 4147554 7955801 BWG_3709 Escherichia coli BW2952 Nin-like protein YP_002928903.1 4146664 D 595496 CDS YP_002928904.1 238903108 7954386 4148447..4148644 1 NC_012759.1 Protein ninG 4148644 7954386 BWG_3710 Escherichia coli BW2952 Protein ninG YP_002928904.1 4148447 D 595496 CDS YP_002928905.1 238903109 7955802 4148641..4148847 1 NC_012759.1 Protein ninH 4148847 7955802 BWG_3711 Escherichia coli BW2952 Protein ninH YP_002928905.1 4148641 D 595496 CDS YP_002928906.1 238903110 7955803 4148825..4149490 1 NC_012759.1 Serine/threonine-protein phosphatase 4149490 7955803 BWG_3712 Escherichia coli BW2952 Serine/threonine-protein phosphatase YP_002928906.1 4148825 D 595496 CDS YP_002928907.1 238903111 7956033 4149487..4150110 1 NC_012759.1 Antitermination protein Q 4150110 7956033 BWG_3713 Escherichia coli BW2952 Antitermination protein Q YP_002928907.1 4149487 D 595496 CDS YP_002928908.1 238903112 7952485 4150787..4151110 1 NC_012759.1 Includes: Lysis protein S; Lysis inhibitor; Holin (gpS protein) 4151110 7952485 BWG_3714 Escherichia coli BW2952 Holin (gpS protein) YP_002928908.1 4150787 D 595496 CDS YP_002928909.1 238903113 7953915 4151094..4151570 1 NC_012759.1 lysozyme 4151570 7953915 BWG_3715 Escherichia coli BW2952 lysozyme YP_002928909.1 4151094 D 595496 CDS YP_002928910.1 238903114 7954187 4151567..4152028 1 NC_012759.1 MG1655 equivalent: unique; DLP12 prophage; putative murein endopeptidase 4152028 rzpD 7954187 rzpD Escherichia coli BW2952 DLP12 prophage; putative murein endopeptidase YP_002928910.1 4151567 D 595496 CDS YP_002928911.1 238903115 7956293 4151787..4151969 1 NC_012759.1 MG1655 equivalent: unique; DLP12 prophage; putative lipoprotein 4151969 rzoD 7956293 rzoD Escherichia coli BW2952 DLP12 prophage; putative lipoprotein YP_002928911.1 4151787 D 595496 CDS YP_002928912.1 238903116 7956294 complement(4152060..4152353) 1 NC_012759.1 MG1655 equivalent: unique; DLP12 prophage; putative lipoprotein 4152353 borD 7956294 borD Escherichia coli BW2952 DLP12 prophage; putative lipoprotein YP_002928912.1 4152060 R 595496 CDS YP_002928913.1 238903117 7956291 complement(4152643..4153053) 1 NC_012759.1 MG1655 equivalent: unique; DLP12 prophage protein 4153053 ybcV 7956291 ybcV Escherichia coli BW2952 DLP12 prophage protein YP_002928913.1 4152643 R 595496 CDS YP_002928914.1 238903118 7956292 4153339..4153545 1 NC_012759.1 MG1655 equivalent: unique; DLP12 prophage protein 4153545 ybcW 7956292 ybcW Escherichia coli BW2952 DLP12 prophage protein YP_002928914.1 4153339 D 595496 CDS YP_002928915.1 238903119 7956295 4154293..4154838 1 NC_012759.1 MG1655 equivalent: unique; DLP12 prophage; DNA packaging protein 4154838 nohB 7956295 nohB Escherichia coli BW2952 DLP12 prophage; DNA packaging protein YP_002928915.1 4154293 D 595496 CDS YP_002928916.1 238903120 7956296 4156735..4156941 1 NC_012759.1 Lambda prophage-derived head-to-tail joining protein W 4156941 7956296 BWG_3722 Escherichia coli BW2952 Lambda prophage-derived head-to-tail joining protein W YP_002928916.1 4156735 D 595496 CDS YP_002928917.1 238903121 7954113 4156938..4158539 1 NC_012759.1 Contains: Protein B*; Portal protein B (GpB) (Minor capsid protein B) 4158539 7954113 BWG_3723 Escherichia coli BW2952 Portal protein B (GpB) (Minor capsid protein B) YP_002928917.1 4156938 D 595496 CDS YP_002928918.1 238903122 7954571 4158520..4159839 1 NC_012759.1 Contains: Capsid assembly protein NU3; Minor capsid protein C (GPC) 4159839 7954571 BWG_3724 Escherichia coli BW2952 Minor capsid protein C (GPC) YP_002928918.1 4158520 D 595496 CDS YP_002928919.1 238903123 7954263 4159849..4160181 1 NC_012759.1 Head decoration protein 4160181 7954263 BWG_3725 Escherichia coli BW2952 Head decoration protein YP_002928919.1 4159849 D 595496 CDS YP_002928920.1 238903124 7953889 4160243..4161262 1 NC_012759.1 Major head protein 4161262 7953889 BWG_3726 Escherichia coli BW2952 Major head protein YP_002928920.1 4160243 D 595496 CDS YP_002928921.1 238903125 7954194 4161304..4161702 1 NC_012759.1 DNA packaging protein FI 4161702 7954194 BWG_3727 Escherichia coli BW2952 DNA packaging protein FI YP_002928921.1 4161304 D 595496 CDS YP_002928922.1 238903126 7953315 4161714..4162067 1 NC_012759.1 Tail attachment protein 4162067 7953315 BWG_3728 Escherichia coli BW2952 Tail attachment protein YP_002928922.1 4161714 D 595496 CDS YP_002928923.1 238903127 7956106 4162079..4162657 1 NC_012759.1 Minor tail protein Z 4162657 7956106 BWG_3729 Escherichia coli BW2952 Minor tail protein Z YP_002928923.1 4162079 D 595496 CDS YP_002928924.1 238903128 7954274 4162654..4163049 1 NC_012759.1 Minor tail protein U 4163049 7954274 BWG_3730 Escherichia coli BW2952 Minor tail protein U YP_002928924.1 4162654 D 595496 CDS YP_002928925.1 238903129 7954273 4163057..4163797 1 NC_012759.1 Major tail protein V 4163797 7954273 BWG_3731 Escherichia coli BW2952 Major tail protein V YP_002928925.1 4163057 D 595496 CDS YP_002928926.1 238903130 7954195 4163813..4164235 1 NC_012759.1 Minor tail protein G 4164235 7954195 BWG_3732 Escherichia coli BW2952 Minor tail protein G YP_002928926.1 4163813 D 595496 CDS YP_002928927.1 238903131 7954269 4164217..4164651 1 NC_012759.1 Minor tail protein T 4164651 7954269 BWG_3733 Escherichia coli BW2952 Minor tail protein T YP_002928927.1 4164217 D 595496 CDS YP_002928928.1 238903132 7954272 4164644..4167205 1 NC_012759.1 Contains: Minor tail protein H*; Minor tail protein H 4167205 7954272 BWG_3734 Escherichia coli BW2952 Minor tail protein H YP_002928928.1 4164644 D 595496 CDS YP_002928929.1 238903133 7954270 4167202..4167531 1 NC_012759.1 Minor tail protein M 4167531 7954270 BWG_3735 Escherichia coli BW2952 Minor tail protein M YP_002928929.1 4167202 D 595496 CDS YP_002928930.1 238903134 7954271 4167531..4168229 1 NC_012759.1 COG4672; hypothetical protein 4168229 7954271 BWG_3736 Escherichia coli BW2952 hypothetical protein YP_002928930.1 4167531 D 595496 CDS YP_002928931.1 238903135 7952650 4168235..4168978 1 NC_012759.1 COG0791; Cell wall-associated hydrolases (invasion-associated proteins) 4168978 7952650 BWG_3737 Escherichia coli BW2952 Cell wall-associated hydrolases (invasion-associated proteins) YP_002928931.1 4168235 D 595496 CDS YP_002928932.1 238903136 7952649 4169279..4169548 1 NC_012759.1 Tail assembly protein I 4169548 7952649 BWG_3738 Escherichia coli BW2952 Tail assembly protein I YP_002928932.1 4169279 D 595496 CDS YP_002928933.1 238903137 7956105 4169609..4173007 1 NC_012759.1 Host specificity protein J 4173007 7956105 BWG_3739 Escherichia coli BW2952 Host specificity protein J YP_002928933.1 4169609 D 595496 CDS YP_002928934.1 238903138 7953921 4173069..4173689 1 NC_012759.1 Outer membrane protein lom precursor 4173689 7953921 BWG_3740 Escherichia coli BW2952 Outer membrane protein lom precursor YP_002928934.1 4173069 D 595496 CDS YP_002928935.1 238903139 7954449 4173754..4174173 1 NC_012759.1 Side tail fiber protein 4174173 7954449 BWG_3741 Escherichia coli BW2952 Side tail fiber protein YP_002928935.1 4173754 D 595496 CDS YP_002928936.1 238903140 7952213 complement(4174500..4175753) 1 NC_012759.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 4175753 lacY 7952213 lacY Escherichia coli BW2952 galactoside permease YP_002928936.1 4174500 R 595496 CDS YP_002928937.1 238903141 7954107 complement(4175805..4179047) 1 NC_012759.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 4179047 lacZ 7954107 lacZ Escherichia coli BW2952 beta-D-galactosidase YP_002928937.1 4175805 R 595496 CDS YP_002928938.1 238903142 7952548 complement(4179047..4180240) 1 NC_012759.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 4180240 7952548 BWG_3745 Escherichia coli BW2952 tryptophan synthase subunit beta YP_002928938.1 4179047 R 595496 CDS YP_002928939.1 238903143 7952211 complement(4180399..4181943) 1 NC_012759.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4181943 malF 7952211 malF Escherichia coli BW2952 maltose transporter membrane protein YP_002928939.1 4180399 R 595496 CDS YP_002928940.1 238903144 7954208 complement(4182097..4183287) 1 NC_012759.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4183287 malE 7954208 malE Escherichia coli BW2952 maltose ABC transporter periplasmic protein YP_002928940.1 4182097 R 595496 CDS YP_002928941.1 238903145 7954209 4183652..4184767 1 NC_012759.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4184767 malK 7954209 malK Escherichia coli BW2952 maltose/maltodextrin transporter ATP-binding protein YP_002928941.1 4183652 D 595496 CDS YP_002928942.1 238903146 7953697 4184839..4186179 1 NC_012759.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4186179 lamB 7953697 lamB Escherichia coli BW2952 maltoporin YP_002928942.1 4184839 D 595496 CDS YP_002928943.1 238903147 7954206 4186422..4187342 1 NC_012759.1 MG1655 equivalent: b4037; maltose regulon periplasmic protein 4187342 malM 7954206 malM Escherichia coli BW2952 maltose regulon periplasmic protein YP_002928943.1 4186422 D 595496 CDS YP_002928944.1 238903148 7954207 4189374..4189871 1 NC_012759.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4189871 ubiC 7954207 ubiC Escherichia coli BW2952 chorismate pyruvate lyase YP_002928944.1 4189374 D 595496 CDS YP_002928945.1 238903149 7952635 4189884..4190756 1 NC_012759.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4190756 ubiA 7952635 ubiA Escherichia coli BW2952 4-hydroxybenzoate octaprenyltransferase YP_002928945.1 4189884 D 595496 CDS YP_002928946.1 238903150 7954557 complement(4190911..4193334) 1 NC_012759.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4193334 plsB 7954557 plsB Escherichia coli BW2952 glycerol-3-phosphate acyltransferase YP_002928946.1 4190911 R 595496 CDS YP_002928947.1 238903151 7953849 4193505..4193873 1 NC_012759.1 MG1655 equivalent: b4042; diacylglycerol kinase 4193873 dgkA 7953849 dgkA Escherichia coli BW2952 diacylglycerol kinase YP_002928947.1 4193505 D 595496 CDS YP_002928948.1 238903152 7953245 4193983..4194591 1 NC_012759.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4194591 lexA 7953245 lexA Escherichia coli BW2952 LexA repressor YP_002928948.1 4193983 D 595496 CDS YP_002928949.1 238903153 7953476 4194610..4195989 1 NC_012759.1 MG1655 equivalent: b4044; DNA-damage-inducible SOS response protein 4195989 dinF 7953476 dinF Escherichia coli BW2952 DNA-damage-inducible SOS response protein YP_002928949.1 4194610 D 595496 CDS YP_002928950.1 238903154 7953486 4196105..4196314 1 NC_012759.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4196314 yjbJ 7953486 yjbJ Escherichia coli BW2952 putative stress-response protein YP_002928950.1 4196105 D 595496 CDS YP_002928951.1 238903155 7955600 complement(4196356..4196871) 1 NC_012759.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4196871 zur 7955600 zur Escherichia coli BW2952 zinc uptake transcriptional repressor YP_002928951.1 4196356 R 595496 CDS YP_002928952.1 238903156 7953483 4197189..4197443 1 NC_012759.1 MG1655 equivalent: b4047; hypothetical protein 4197443 yjbL 7953483 yjbL Escherichia coli BW2952 hypothetical protein YP_002928952.1 4197189 D 595496 CDS YP_002928953.1 238903157 7955520 4197467..4198174 1 NC_012759.1 MG1655 equivalent: b4048; hypothetical protein 4198174 yjbM 7955520 yjbM Escherichia coli BW2952 hypothetical protein YP_002928953.1 4197467 D 595496 CDS YP_002928954.1 238903158 7955521 4198582..4199574 1 NC_012759.1 MG1655 equivalent: b4049; tRNA-dihydrouridine synthase A 4199574 dusA 7955521 dusA Escherichia coli BW2952 tRNA-dihydrouridine synthase A YP_002928954.1 4198582 D 595496 CDS YP_002928955.1 238903159 7956204 4199708..4199950 1 NC_012759.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4199950 pspG 7956204 pspG Escherichia coli BW2952 phage shock protein G YP_002928955.1 4199708 D 595496 CDS YP_002928956.1 238903160 7954504 complement(4200116..4201099) 1 NC_012759.1 MG1655 equivalent: b4051; quinone oxidoreductase 4201099 qor 7954504 qor Escherichia coli BW2952 quinone oxidoreductase YP_002928956.1 4200116 R 595496 CDS YP_002928957.1 238903161 7955889 4201182..4202597 1 NC_012759.1 unwinds double stranded DNA; replicative DNA helicase 4202597 dnaB 7955889 dnaB Escherichia coli BW2952 replicative DNA helicase YP_002928957.1 4201182 D 595496 CDS YP_002928958.1 238903162 7955939 4202650..4203729 1 NC_012759.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4203729 alr 7955939 alr Escherichia coli BW2952 alanine racemase YP_002928958.1 4202650 D 595496 CDS YP_002928959.1 238903163 7952438 4203982..4205175 1 NC_012759.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4205175 tyrB 7952438 tyrB Escherichia coli BW2952 aromatic amino acid aminotransferase YP_002928959.1 4203982 D 595496 CDS YP_002928960.1 238903164 7956221 complement(4205677..4205880) 1 NC_012759.1 MG1655 equivalent: b4621; hypothetical protein 4205880 yjbS 7956221 yjbS Escherichia coli BW2952 hypothetical protein YP_002928960.1 4205677 R 595496 CDS YP_002928961.1 238903165 7953971 4206282..4206995 1 NC_012759.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4206995 aphA 7953971 aphA Escherichia coli BW2952 acid phosphatase/phosphotransferase YP_002928961.1 4206282 D 595496 CDS YP_002928962.1 238903166 7952407 4207106..4207522 1 NC_012759.1 MG1655 equivalent: b4056; hypothetical protein 4207522 yjbQ 7952407 yjbQ Escherichia coli BW2952 hypothetical protein YP_002928962.1 4207106 D 595496 CDS YP_002928963.1 238903167 7953054 4207526..4207882 1 NC_012759.1 MG1655 equivalent: b4057; hypothetical protein 4207882 yjbR 7953054 yjbR Escherichia coli BW2952 hypothetical protein YP_002928963.1 4207526 D 595496 CDS YP_002928964.1 238903168 7953055 complement(4207917..4210739) 1 NC_012759.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4210739 uvrA 7953055 uvrA Escherichia coli BW2952 excinuclease ABC subunit A YP_002928964.1 4207917 R 595496 CDS YP_002928965.1 238903169 7952523 4210993..4211529 1 NC_012759.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4211529 ssb 7952523 ssb Escherichia coli BW2952 single-stranded DNA-binding protein YP_002928965.1 4210993 D 595496 CDS YP_002928966.1 238903170 7956046 complement(4211628..4211909) 1 NC_012759.1 MG1655 equivalent: b4060; putative inner membrane protein 4211909 yjcB 7956046 yjcB Escherichia coli BW2952 putative inner membrane protein YP_002928966.1 4211628 R 595496 CDS YP_002928967.1 238903171 7955016 4212339..4213925 1 NC_012759.1 MG1655 equivalent: b4061; putative signal transduction protein (EAL domain containing protein) 4213925 yjcC 7955016 yjcC Escherichia coli BW2952 putative signal transduction protein (EAL domain containing protein) YP_002928967.1 4212339 D 595496 CDS YP_002928968.1 238903172 7955592 complement(4213928..4214251) 1 NC_012759.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4214251 soxS 7955592 soxS Escherichia coli BW2952 DNA-binding transcriptional regulator SoxS YP_002928968.1 4213928 R 595496 CDS YP_002928969.1 238903173 7953415 4214337..4214801 1 NC_012759.1 MG1655 equivalent: b4063; DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 4214801 soxR 7953415 soxR Escherichia coli BW2952 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing YP_002928969.1 4214337 D 595496 CDS YP_002928970.1 238903174 7952099 4215347..4216696 1 NC_012759.1 MG1655 equivalent: b4064; putative permease 4216696 yjcD 7952099 yjcD Escherichia coli BW2952 putative permease YP_002928970.1 4215347 D 595496 CDS YP_002928971.1 238903175 7955309 4216848..4218497 1 NC_012759.1 MG1655 equivalent: b4065; putative cation/proton antiporter 4218497 yjcE 7955309 yjcE Escherichia coli BW2952 putative cation/proton antiporter YP_002928971.1 4216848 D 595496 CDS YP_002928972.1 238903176 7952207 complement(4220122..4221771) 1 NC_012759.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4221771 actP 7952207 actP Escherichia coli BW2952 acetate permease YP_002928972.1 4220122 R 595496 CDS YP_002928973.1 238903177 7952389 complement(4221768..4222082) 1 NC_012759.1 MG1655 equivalent: b4068; acetate transport inner membrane protein 4222082 yjcH 7952389 yjcH Escherichia coli BW2952 acetate transport inner membrane protein YP_002928973.1 4221768 R 595496 CDS YP_002928974.1 238903178 7952742 complement(4222282..4224240) 1 NC_012759.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4224240 acs 7952742 acs Escherichia coli BW2952 acetyl-CoA synthetase YP_002928974.1 4222282 R 595496 CDS YP_002928975.1 238903179 7952402 4224633..4226069 1 NC_012759.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4226069 nrfA 7952402 nrfA Escherichia coli BW2952 cytochrome c552 YP_002928975.1 4224633 D 595496 CDS YP_002928976.1 238903180 7954399 4226114..4226680 1 NC_012759.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4226680 nrfB 7954399 nrfB Escherichia coli BW2952 cytochrome c nitrite reductase pentaheme subunit YP_002928976.1 4226114 D 595496 CDS YP_002928977.1 238903181 7954400 4226677..4227348 1 NC_012759.1 MG1655 equivalent: b4072; formate-dependent nitrite reductase, 4Fe4S subunit 4227348 nrfC 7954400 nrfC Escherichia coli BW2952 formate-dependent nitrite reductase, 4Fe4S subunit YP_002928977.1 4226677 D 595496 CDS YP_002928978.1 238903182 7953627 4227345..4228301 1 NC_012759.1 MG1655 equivalent: b4073; formate-dependent nitrite reductase, membrane subunit 4228301 nrfD 7953627 nrfD Escherichia coli BW2952 formate-dependent nitrite reductase, membrane subunit YP_002928978.1 4227345 D 595496 CDS YP_002928979.1 238903183 7953628 4228381..4230039 1 NC_012759.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4230039 nrfE 7953628 nrfE Escherichia coli BW2952 heme lyase subunit NrfE YP_002928979.1 4228381 D 595496 CDS YP_002928980.1 238903184 7953899 4230032..4230415 1 NC_012759.1 MG1655 equivalent: b4075; formate-dependent nitrite reductase complex subunit NrfF 4230415 nrfF 7953899 nrfF Escherichia coli BW2952 formate-dependent nitrite reductase complex subunit NrfF YP_002928980.1 4230032 D 595496 CDS YP_002928981.1 238903185 7953900 4230412..4231008 1 NC_012759.1 MG1655 equivalent: b4076; formate-dependent nitrite reductase complex subunit NrfG 4231008 nrfG 7953900 nrfG Escherichia coli BW2952 formate-dependent nitrite reductase complex subunit NrfG YP_002928981.1 4230412 D 595496 CDS YP_002928982.1 238903186 7953901 4231350..4232663 1 NC_012759.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4232663 gltP 7953901 gltP Escherichia coli BW2952 glutamate/aspartate:proton symporter YP_002928982.1 4231350 D 595496 CDS YP_002928983.1 238903187 7953825 complement(4233194..4233883) 1 NC_012759.1 MG1655 equivalent: b4078; hypothetical protein 4233883 yjcO 7953825 yjcO Escherichia coli BW2952 hypothetical protein YP_002928983.1 4233194 R 595496 CDS YP_002928984.1 238903188 7952895 complement(4233977..4236124) 1 NC_012759.1 MG1655 equivalent: b4079; formate dehydrogenase-H, selenopolypeptide subunit 4236124 fdhF 7952895 fdhF Escherichia coli BW2952 formate dehydrogenase-H, selenopolypeptide subunit YP_002928984.1 4233977 R 595496 CDS YP_002928985.1 238903189 7953618 complement(4236322..4237788) 1 NC_012759.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP 4237788 mdtP 7953618 mdtP Escherichia coli BW2952 putative outer membrane efflux protein MdtP YP_002928985.1 4236322 R 595496 CDS YP_002928986.1 238903190 7955197 complement(4237785..4239836) 1 NC_012759.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4239836 mdtO 7955197 mdtO Escherichia coli BW2952 multidrug efflux system protein MdtO YP_002928986.1 4237785 R 595496 CDS YP_002928987.1 238903191 7955174 complement(4239836..4240867) 1 NC_012759.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4240867 mdtN 7955174 mdtN Escherichia coli BW2952 multidrug resistance protein MdtN YP_002928987.1 4239836 R 595496 CDS YP_002928988.1 238903192 7955139 complement(4240886..4241161) 1 NC_012759.1 MG1655 equivalent: b4622; hypothetical protein 4241161 ytcA 7955139 ytcA Escherichia coli BW2952 hypothetical protein YP_002928988.1 4240886 R 595496 CDS YP_002928989.1 238903193 7953972 complement(4241370..4243355) 1 NC_012759.1 MG1655 equivalent: b4083; putative alkyl sulfatase 4243355 yjcS 7953972 yjcS Escherichia coli BW2952 putative alkyl sulfatase YP_002928989.1 4241370 R 595496 CDS YP_002928990.1 238903194 7954632 complement(4243628..4244557) 1 NC_012759.1 MG1655 equivalent: b4084; D-allose kinase 4244557 alsK 7954632 alsK Escherichia coli BW2952 D-allose kinase YP_002928990.1 4243628 R 595496 CDS YP_002928991.1 238903195 7953222 complement(4244541..4245236) 1 NC_012759.1 MG1655 equivalent: b4085; allulose-6-phosphate 3-epimerase 4245236 alsE 7953222 alsE Escherichia coli BW2952 allulose-6-phosphate 3-epimerase YP_002928991.1 4244541 R 595496 CDS YP_002928992.1 238903196 7952454 complement(4245247..4246227) 1 NC_012759.1 MG1655 equivalent: b4086; D-allose transporter subunit 4246227 alsC 7952454 alsC Escherichia coli BW2952 D-allose transporter subunit YP_002928992.1 4245247 R 595496 CDS YP_002928993.1 238903197 7953223 complement(4246206..4247738) 1 NC_012759.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4247738 alsA 7953223 alsA Escherichia coli BW2952 D-allose transporter ATP-binding protein YP_002928993.1 4246206 R 595496 CDS YP_002928994.1 238903198 7953670 complement(4247865..4248800) 1 NC_012759.1 MG1655 equivalent: b4088; D-allose transporter subunit 4248800 alsB 7953670 alsB Escherichia coli BW2952 D-allose transporter subunit YP_002928994.1 4247865 R 595496 CDS YP_002928995.1 238903199 7953224 complement(4248859..4249749) 1 NC_012759.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4249749 rpiR 7953224 rpiR Escherichia coli BW2952 DNA-binding transcriptional repressor RpiR YP_002928995.1 4248859 R 595496 CDS YP_002928996.1 238903200 7953459 4250108..4250557 1 NC_012759.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4250557 rpiB 7953459 rpiB Escherichia coli BW2952 ribose-5-phosphate isomerase B YP_002928996.1 4250108 D 595496 CDS YP_002928997.1 238903201 7955972 4250626..4250955 1 NC_012759.1 MG1655 equivalent: b4487; hypothetical protein 4250955 yjdP 7955972 yjdP Escherichia coli BW2952 hypothetical protein YP_002928997.1 4250626 D 595496 CDS YP_002928998.1 238903202 7953069 complement(4251102..4251860) 1 NC_012759.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4251860 phnP 7953069 phnP Escherichia coli BW2952 carbon-phosphorus lyase complex accessory protein YP_002928998.1 4251102 R 595496 CDS YP_002928999.1 238903203 7952598 complement(4251862..4252296) 1 NC_012759.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4252296 phnO 7952598 phnO Escherichia coli BW2952 aminoalkylphosphonic acid N-acetyltransferase YP_002928999.1 4251862 R 595496 CDS YP_002929000.1 238903204 7954619 complement(4252283..4252840) 1 NC_012759.1 MG1655 equivalent: b4094; ribose 1,5-bisphosphokinase 4252840 phnN 7954619 phnN Escherichia coli BW2952 ribose 1,5-bisphosphokinase YP_002929000.1 4252283 R 595496 CDS YP_002929001.1 238903205 7955971 complement(4252840..4253976) 1 NC_012759.1 MG1655 equivalent: b4095; carbon-phosphorus lyase complex subunit 4253976 phnM 7955971 phnM Escherichia coli BW2952 carbon-phosphorus lyase complex subunit YP_002929001.1 4252840 R 595496 CDS YP_002929002.1 238903206 7952599 complement(4253973..4254653) 1 NC_012759.1 MG1655 equivalent: b4096; carbon-phosphorus lyase complex subunit 4254653 phnL 7952599 phnL Escherichia coli BW2952 carbon-phosphorus lyase complex subunit YP_002929002.1 4253973 R 595496 CDS YP_002929003.1 238903207 7952600 complement(4254764..4255522) 1 NC_012759.1 MG1655 equivalent: b4097; phosphonate C-P lyase system protein PhnK 4255522 phnK 7952600 phnK Escherichia coli BW2952 phosphonate C-P lyase system protein PhnK YP_002929003.1 4254764 R 595496 CDS YP_002929004.1 238903208 7952601 complement(4255519..4256364) 1 NC_012759.1 MG1655 equivalent: b4098; carbon-phosphorus lyase complex subunit 4256364 phnJ 7952601 phnJ Escherichia coli BW2952 carbon-phosphorus lyase complex subunit YP_002929004.1 4255519 R 595496 CDS YP_002929005.1 238903209 7952602 complement(4256357..4257421) 1 NC_012759.1 MG1655 equivalent: b4099; carbon-phosphorus lyase complex subunit 4257421 phnI 7952602 phnI Escherichia coli BW2952 carbon-phosphorus lyase complex subunit YP_002929005.1 4256357 R 595496 CDS YP_002929006.1 238903210 7952603 complement(4257421..4258005) 1 NC_012759.1 MG1655 equivalent: b4100; carbon-phosphorus lyase complex subunit 4258005 phnH 7952603 phnH Escherichia coli BW2952 carbon-phosphorus lyase complex subunit YP_002929006.1 4257421 R 595496 CDS YP_002929007.1 238903211 7952604 complement(4258002..4258454) 1 NC_012759.1 MG1655 equivalent: b4101; carbon-phosphorus lyase complex subunit 4258454 phnG 7952604 phnG Escherichia coli BW2952 carbon-phosphorus lyase complex subunit YP_002929007.1 4258002 R 595496 CDS YP_002929008.1 238903212 7952605 complement(4258455..4259180) 1 NC_012759.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4259180 phnF 7952605 phnF Escherichia coli BW2952 phosphonate metabolism transcriptional regulator PhnF YP_002929008.1 4258455 R 595496 CDS YP_002929009.1 238903213 7954821 complement(4260094..4261110) 1 NC_012759.1 MG1655 equivalent: b4105; phosphonate/organophosphate ester transporter subunit 4261110 phnD 7954821 phnD Escherichia coli BW2952 phosphonate/organophosphate ester transporter subunit YP_002929009.1 4260094 R 595496 CDS YP_002929010.1 238903214 7954544 complement(4261135..4261923) 1 NC_012759.1 MG1655 equivalent: b4106; phosphonate/organophosphate ester transporter subunit 4261923 phnC 7954544 phnC Escherichia coli BW2952 phosphonate/organophosphate ester transporter subunit YP_002929010.1 4261135 R 595496 CDS YP_002929011.1 238903215 7954545 complement(4262056..4262499) 1 NC_012759.1 MG1655 equivalent: b4107; hypothetical protein 4262499 yjdN 7954545 yjdN Escherichia coli BW2952 hypothetical protein YP_002929011.1 4262056 R 595496 CDS YP_002929012.1 238903216 7952896 complement(4263157..4263492) 1 NC_012759.1 MG1655 equivalent: b4108; hypothetical protein 4263492 yjdM 7952896 yjdM Escherichia coli BW2952 hypothetical protein YP_002929012.1 4263157 R 595496 CDS YP_002929013.1 238903217 7952897 4263893..4266121 1 NC_012759.1 MG1655 equivalent: b4109; hypothetical protein 4266121 yjdA 7952897 yjdA Escherichia coli BW2952 hypothetical protein YP_002929013.1 4263893 D 595496 CDS YP_002929014.1 238903218 7953092 4266118..4266996 1 NC_012759.1 MG1655 equivalent: b4110; hypothetical protein 4266996 yjcZ 7953092 yjcZ Escherichia coli BW2952 hypothetical protein YP_002929014.1 4266118 D 595496 CDS YP_002929015.1 238903219 7953056 4267260..4268762 1 NC_012759.1 MG1655 equivalent: b4111; proline/glycine betaine transporter 4268762 proP 7953056 proP Escherichia coli BW2952 proline/glycine betaine transporter YP_002929015.1 4267260 D 595496 CDS YP_002929016.1 238903220 7955769 complement(4268939..4270030) 1 NC_012759.1 MG1655 equivalent: b4112; sensor protein BasS/PmrB 4270030 basS 7955769 basS Escherichia coli BW2952 sensor protein BasS/PmrB YP_002929016.1 4268939 R 595496 CDS YP_002929017.1 238903221 7956013 complement(4270040..4270708) 1 NC_012759.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4270708 basR 7956013 basR Escherichia coli BW2952 DNA-binding transcriptional regulator BasR YP_002929017.1 4270040 R 595496 CDS YP_002929018.1 238903222 7953346 complement(4270705..4272348) 1 NC_012759.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein 4272348 eptA 7953346 eptA Escherichia coli BW2952 putative cell division protein YP_002929018.1 4270705 R 595496 CDS YP_002929019.1 238903223 7955144 complement(4272452..4273789) 1 NC_012759.1 MG1655 equivalent: b4115; arginine:agmatin antiporter 4273789 adiC 7955144 adiC Escherichia coli BW2952 arginine:agmatin antiporter YP_002929019.1 4272452 R 595496 CDS YP_002929020.1 238903224 7952500 complement(4273926..4274687) 1 NC_012759.1 MG1655 equivalent: b4116; DNA-binding transcriptional activator 4274687 adiY 7952500 adiY Escherichia coli BW2952 DNA-binding transcriptional activator YP_002929020.1 4273926 R 595496 CDS YP_002929021.1 238903225 7953372 complement(4275012..4277282) 1 NC_012759.1 MG1655 equivalent: b4117; biodegradative arginine decarboxylase 4277282 adiA 7953372 adiA Escherichia coli BW2952 biodegradative arginine decarboxylase YP_002929021.1 4275012 R 595496 CDS YP_002929022.1 238903226 7952577 complement(4277478..4278386) 1 NC_012759.1 MG1655 equivalent: b4118; DNA-binding transcriptional regulator MelR 4278386 melR 7952577 melR Escherichia coli BW2952 DNA-binding transcriptional regulator MelR YP_002929022.1 4277478 R 595496 CDS YP_002929023.1 238903227 7953416 4278669..4280024 1 NC_012759.1 MG1655 equivalent: b4119; alpha-galactosidase, NAD(P)-binding 4280024 melA 7953416 melA Escherichia coli BW2952 alpha-galactosidase, NAD(P)-binding YP_002929023.1 4278669 D 595496 CDS YP_002929024.1 238903228 7952457 4280139..4281548 1 NC_012759.1 MG1655 equivalent: b4120; melibiose:sodium symporter 4281548 melB 7952457 melB Escherichia coli BW2952 melibiose:sodium symporter YP_002929024.1 4280139 D 595496 CDS YP_002929025.1 238903229 7954221 complement(4281687..4282316) 1 NC_012759.1 MG1655 equivalent: b4121; hypothetical protein 4282316 yjdF 7954221 yjdF Escherichia coli BW2952 hypothetical protein YP_002929025.1 4281687 R 595496 CDS YP_002929026.1 238903230 7952693 complement(4282438..4284084) 1 NC_012759.1 MG1655 equivalent: b4122; anaerobic class I fumarate hydratase (fumarase B) 4284084 fumB 7952693 fumB Escherichia coli BW2952 anaerobic class I fumarate hydratase (fumarase B) YP_002929026.1 4282438 R 595496 CDS YP_002929027.1 238903231 7952477 complement(4284162..4285502) 1 NC_012759.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4285502 dcuB 7952477 dcuB Escherichia coli BW2952 anaerobic C4-dicarboxylate transporter YP_002929027.1 4284162 R 595496 CDS YP_002929028.1 238903232 7952586 complement(4286073..4286792) 1 NC_012759.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4286792 dcuR 7952586 dcuR Escherichia coli BW2952 DNA-binding transcriptional activator DcuR YP_002929028.1 4286073 R 595496 CDS YP_002929029.1 238903233 7953351 complement(4286789..4288420) 1 NC_012759.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4288420 dcuS 7953351 dcuS Escherichia coli BW2952 sensory histidine kinase DcuS YP_002929029.1 4286789 R 595496 CDS YP_002929030.1 238903234 7956018 4288601..4288831 1 NC_012759.1 MG1655 equivalent: b4126; hypothetical protein 4288831 yjdI 7956018 yjdI Escherichia coli BW2952 hypothetical protein YP_002929030.1 4288601 D 595496 CDS YP_002929031.1 238903235 7953057 4288843..4289115 1 NC_012759.1 MG1655 equivalent: b4127; putative acyltransferase with acyl-CoA N-acyltransferase domain 4289115 yjdJ 7953057 yjdJ Escherichia coli BW2952 putative acyltransferase with acyl-CoA N-acyltransferase domain YP_002929031.1 4288843 D 595496 CDS YP_002929032.1 238903236 7954622 4289342..4289638 1 NC_012759.1 MG1655 equivalent: b4128; hypothetical protein 4289638 yjdK 7954622 yjdK Escherichia coli BW2952 hypothetical protein YP_002929032.1 4289342 D 595496 CDS YP_002929033.1 238903237 7955522 4289666..4289839 1 NC_012759.1 MG1655 equivalent: b4559; hypothetical protein 4289839 yjdO 7955522 yjdO Escherichia coli BW2952 hypothetical protein YP_002929033.1 4289666 D 595496 CDS YP_002929034.1 238903238 7955539 complement(4289958..4291475) 1 NC_012759.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4291475 lysU 7955539 lysU Escherichia coli BW2952 lysyl-tRNA synthetase YP_002929034.1 4289958 R 595496 CDS YP_002929035.1 238903239 7954184 complement(4291712..4293169) 1 NC_012759.1 MG1655 equivalent: b4130; putative transporter 4293169 yjdL 7954184 yjdL Escherichia coli BW2952 putative transporter YP_002929035.1 4291712 R 595496 CDS YP_002929036.1 238903240 7955674 complement(4293228..4295375) 1 NC_012759.1 MG1655 equivalent: b4131; lysine decarboxylase 1 4295375 cadA 7955674 cadA Escherichia coli BW2952 lysine decarboxylase 1 YP_002929036.1 4293228 R 595496 CDS YP_002929037.1 238903241 7954180 complement(4295455..4296789) 1 NC_012759.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4296789 cadB 7954180 cadB Escherichia coli BW2952 lysine/cadaverine antiporter YP_002929037.1 4295455 R 595496 CDS YP_002929038.1 238903242 7955128 complement(4297154..4298692) 1 NC_012759.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4298692 cadC 7955128 cadC Escherichia coli BW2952 DNA-binding transcriptional activator CadC YP_002929038.1 4297154 R 595496 CDS YP_002929039.1 238903243 7952074 complement(4299491..4300066) 1 NC_012759.1 MG1655 equivalent: b4135; putative transcriptional regulator 4300066 yjdC 7952074 yjdC Escherichia coli BW2952 putative transcriptional regulator YP_002929039.1 4299491 R 595496 CDS YP_002929040.1 238903244 7955631 complement(4300103..4301800) 1 NC_012759.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4301800 dipZ 7955631 dipZ Escherichia coli BW2952 thiol:disulfide interchange protein YP_002929040.1 4300103 R 595496 CDS YP_002929041.1 238903245 7953746 complement(4301776..4302114) 1 NC_012759.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4302114 cutA 7953746 cutA Escherichia coli BW2952 divalent-cation tolerance protein CutA YP_002929041.1 4301776 R 595496 CDS YP_002929042.1 238903246 7953095 complement(4302230..4303531) 1 NC_012759.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4303531 dcuA 7953095 dcuA Escherichia coli BW2952 anaerobic C4-dicarboxylate transporter YP_002929042.1 4302230 R 595496 CDS YP_002929043.1 238903247 7952587 complement(4303649..4305085) 1 NC_012759.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4305085 aspA 7952587 aspA Escherichia coli BW2952 aspartate ammonia-lyase YP_002929043.1 4303649 R 595496 CDS YP_002929044.1 238903248 7952512 4305422..4305898 1 NC_012759.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4305898 fxsA 7952512 fxsA Escherichia coli BW2952 FxsA protein YP_002929044.1 4305422 D 595496 CDS YP_002929045.1 238903249 7953997 complement(4305914..4307170) 1 NC_012759.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 4307170 yjeH 7953997 yjeH Escherichia coli BW2952 inner membrane protein YjeH YP_002929045.1 4305914 R 595496 CDS YP_002929046.1 238903250 7955675 4307446..4307739 1 NC_012759.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4307739 groES 7955675 groES Escherichia coli BW2952 co-chaperonin GroES YP_002929046.1 4307446 D 595496 CDS YP_002929047.1 238903251 7953140 4307783..4309429 1 NC_012759.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4309429 groEL 7953140 groEL Escherichia coli BW2952 chaperonin GroEL YP_002929047.1 4307783 D 595496 CDS YP_002929048.1 238903252 7953141 4309567..4309920 1 NC_012759.1 MG1655 equivalent: b4144; hypothetical protein 4309920 yjeI 7953141 yjeI Escherichia coli BW2952 hypothetical protein YP_002929048.1 4309567 D 595496 CDS YP_002929049.1 238903253 7953058 complement(4310123..4310992) 1 NC_012759.1 MG1655 equivalent: b4145; hypothetical protein 4310992 yjeJ 7953058 yjeJ Escherichia coli BW2952 hypothetical protein YP_002929049.1 4310123 R 595496 CDS YP_002929050.1 238903254 7955426 complement(4311387..4312415) 1 NC_012759.1 MG1655 equivalent: b4146; putative lysine aminomutase 4312415 yjeK 7955426 yjeK Escherichia coli BW2952 putative lysine aminomutase YP_002929050.1 4311387 R 595496 CDS YP_002929051.1 238903255 7955127 4312457..4313023 1 NC_012759.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4313023 efp 7955127 efp Escherichia coli BW2952 elongation factor P YP_002929051.1 4312457 D 595496 CDS YP_002929052.1 238903256 7953514 4313075..4313200 1 NC_012759.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4313200 ecnA 7953514 ecnA Escherichia coli BW2952 entericidin A YP_002929052.1 4313075 D 595496 CDS YP_002929053.1 238903257 7953525 4313311..4313457 1 NC_012759.1 MG1655 equivalent: b4411; entericidin B membrane lipoprotein 4313457 ecnB 7953525 ecnB Escherichia coli BW2952 entericidin B membrane lipoprotein YP_002929053.1 4313311 D 595496 CDS YP_002929054.1 238903258 7953526 4313633..4313950 1 NC_012759.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4313950 sugE 7953526 sugE Escherichia coli BW2952 quaternary ammonium compound-resistance protein SugE YP_002929054.1 4313633 D 595496 CDS YP_002929055.1 238903259 7954307 complement(4313947..4314480) 1 NC_012759.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4314480 blc 7954307 blc Escherichia coli BW2952 outer membrane lipoprotein Blc YP_002929055.1 4313947 R 595496 CDS YP_002929056.1 238903260 7954440 complement(4314569..4315702) 1 NC_012759.1 MG1655 equivalent: b4150; beta-lactamase 4315702 ampC 7954440 ampC Escherichia coli BW2952 beta-lactamase YP_002929056.1 4314569 R 595496 CDS YP_002929057.1 238903261 7952553 complement(4315765..4316124) 1 NC_012759.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4316124 frdD 7952553 frdD Escherichia coli BW2952 fumarate reductase subunit D YP_002929057.1 4315765 R 595496 CDS YP_002929058.1 238903262 7953646 complement(4316135..4316530) 1 NC_012759.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4316530 frdC 7953646 frdC Escherichia coli BW2952 fumarate reductase subunit C YP_002929058.1 4316135 R 595496 CDS YP_002929059.1 238903263 7953647 complement(4316541..4317275) 1 NC_012759.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4317275 frdB 7953647 frdB Escherichia coli BW2952 fumarate reductase iron-sulfur subunit YP_002929059.1 4316541 R 595496 CDS YP_002929060.1 238903264 7953645 complement(4317268..4319076) 1 NC_012759.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4319076 frdA 7953645 frdA Escherichia coli BW2952 fumarate reductase flavoprotein subunit YP_002929060.1 4317268 R 595496 CDS YP_002929061.1 238903265 7953644 4319401..4320378 1 NC_012759.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4320378 poxA 7953644 poxA Escherichia coli BW2952 lysyl-tRNA synthetase YP_002929061.1 4319401 D 595496 CDS YP_002929062.1 238903266 7955130 4320597..4322099 1 NC_012759.1 MG1655 equivalent: b4156; putative transporter 4322099 yjeM 7955130 yjeM Escherichia coli BW2952 putative transporter YP_002929062.1 4320597 D 595496 CDS YP_002929063.1 238903267 7955715 4322151..4322465 1 NC_012759.1 MG1655 equivalent: b4157; hypothetical protein 4322465 yjeN 7955715 yjeN Escherichia coli BW2952 hypothetical protein YP_002929063.1 4322151 D 595496 CDS YP_002929064.1 238903268 7955523 4322462..4322776 1 NC_012759.1 MG1655 equivalent: b4158; hypothetical protein 4322776 yjeO 7955523 yjeO Escherichia coli BW2952 hypothetical protein YP_002929064.1 4322462 D 595496 CDS YP_002929065.1 238903269 7952734 complement(4322805..4326128) 1 NC_012759.1 MG1655 equivalent: b4159; hypothetical protein 4326128 yjeP 7952734 yjeP Escherichia coli BW2952 hypothetical protein YP_002929065.1 4322805 R 595496 CDS YP_002929066.1 238903270 7955137 complement(4326150..4327118) 1 NC_012759.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4327118 psd 7955137 psd Escherichia coli BW2952 phosphatidylserine decarboxylase YP_002929066.1 4326150 R 595496 CDS YP_002929067.1 238903271 7954525 complement(4327215..4328267) 1 NC_012759.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4328267 rsgA 7954525 rsgA Escherichia coli BW2952 ribosome-associated GTPase YP_002929067.1 4327215 R 595496 CDS YP_002929068.1 238903272 7955979 4328362..4328907 1 NC_012759.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4328907 orn 7955979 orn Escherichia coli BW2952 oligoribonuclease YP_002929068.1 4328362 D 595496 CDS YP_002929069.1 238903273 7952165 complement(4329686..4330825) 1 NC_012759.1 MG1655 equivalent: b4166; putative Fe-S electron transport protein 4330825 yjeS 7952165 yjeS Escherichia coli BW2952 putative Fe-S electron transport protein YP_002929069.1 4329686 R 595496 CDS YP_002929070.1 238903274 7954871 4330824..4332371 1 NC_012759.1 MG1655 equivalent: b4167; hypothetical protein 4332371 yjeF 7954871 yjeF Escherichia coli BW2952 hypothetical protein YP_002929070.1 4330824 D 595496 CDS YP_002929071.1 238903275 7954675 4332343..4332804 1 NC_012759.1 possibly involved in cell wall synthesis; putative ATPase 4332804 yjeE 7954675 yjeE Escherichia coli BW2952 putative ATPase YP_002929071.1 4332343 D 595496 CDS YP_002929072.1 238903276 7952527 4332823..4334160 1 NC_012759.1 MG1655 equivalent: b4169; N-acetylmuramoyl-l-alanine amidase II 4334160 amiB 7952527 amiB Escherichia coli BW2952 N-acetylmuramoyl-l-alanine amidase II YP_002929072.1 4332823 D 595496 CDS YP_002929073.1 238903277 7954345 4334170..4336017 1 NC_012759.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4336017 mutL 7954345 mutL Escherichia coli BW2952 DNA mismatch repair protein YP_002929073.1 4334170 D 595496 CDS YP_002929074.1 238903278 7954256 4336010..4336960 1 NC_012759.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4336960 miaA 7954256 miaA Escherichia coli BW2952 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002929074.1 4336010 D 595496 CDS YP_002929075.1 238903279 7953233 4337046..4337354 1 NC_012759.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4337354 hfq 7953233 hfq Escherichia coli BW2952 RNA-binding protein Hfq YP_002929075.1 4337046 D 595496 CDS YP_002929076.1 238903280 7953907 4337430..4338710 1 NC_012759.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4338710 hflX 7953907 hflX Escherichia coli BW2952 putative GTPase HflX YP_002929076.1 4337430 D 595496 CDS YP_002929077.1 238903281 7954940 4338796..4340055 1 NC_012759.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4340055 hflK 7954940 hflK Escherichia coli BW2952 FtsH protease regulator HflK YP_002929077.1 4338796 D 595496 CDS YP_002929078.1 238903282 7954275 4340058..4341062 1 NC_012759.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4341062 hflC 7954275 hflC Escherichia coli BW2952 FtsH protease regulator HflC YP_002929078.1 4340058 D 595496 CDS YP_002929079.1 238903283 7954276 4341144..4341341 1 NC_012759.1 MG1655 equivalent: b4176; hypothetical protein 4341341 yjeT 7954276 yjeT Escherichia coli BW2952 hypothetical protein YP_002929079.1 4341144 D 595496 CDS YP_002929080.1 238903284 7952735 4341445..4342743 1 NC_012759.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4342743 purA 7952735 purA Escherichia coli BW2952 adenylosuccinate synthetase YP_002929080.1 4341445 D 595496 CDS YP_002929081.1 238903285 7952425 4342948..4343373 1 NC_012759.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4343373 nsrR 7952425 nsrR Escherichia coli BW2952 transcriptional repressor NsrR YP_002929081.1 4342948 D 595496 CDS YP_002929082.1 238903286 7954818 4343412..4345853 1 NC_012759.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4345853 rnr 7954818 rnr Escherichia coli BW2952 exoribonuclease R YP_002929082.1 4343412 D 595496 CDS YP_002929083.1 238903287 7953549 4346033..4346764 1 NC_012759.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4346764 rlmB 7953549 rlmB Escherichia coli BW2952 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002929083.1 4346033 D 595496 CDS YP_002929084.1 238903288 7952241 4346891..4347292 1 NC_012759.1 MG1655 equivalent: b4181; hypothetical protein 4347292 yjfI 7952241 yjfI Escherichia coli BW2952 hypothetical protein YP_002929084.1 4346891 D 595496 CDS YP_002929085.1 238903289 7953059 4347311..4348009 1 NC_012759.1 MG1655 equivalent: b4182; putative transcriptional regulator effector protein 4348009 yjfJ 7953059 yjfJ Escherichia coli BW2952 putative transcriptional regulator effector protein YP_002929085.1 4347311 D 595496 CDS YP_002929086.1 238903290 7955642 4348060..4348719 1 NC_012759.1 MG1655 equivalent: b4183; hypothetical protein 4348719 yjfK 7955642 yjfK Escherichia coli BW2952 hypothetical protein YP_002929086.1 4348060 D 595496 CDS YP_002929087.1 238903291 7953060 4348737..4349135 1 NC_012759.1 MG1655 equivalent: b4184; hypothetical protein 4349135 yjfL 7953060 yjfL Escherichia coli BW2952 hypothetical protein YP_002929087.1 4348737 D 595496 CDS YP_002929088.1 238903292 7952736 4349145..4349783 1 NC_012759.1 MG1655 equivalent: b4185; hypothetical protein 4349783 yjfM 7952736 yjfM Escherichia coli BW2952 hypothetical protein YP_002929088.1 4349145 D 595496 CDS YP_002929089.1 238903293 7953061 4349786..4350949 1 NC_012759.1 MG1655 equivalent: b4186; putative synthetase/amidase 4350949 yjfC 7953061 yjfC Escherichia coli BW2952 putative synthetase/amidase YP_002929089.1 4349786 D 595496 CDS YP_002929090.1 238903294 7955617 4351033..4352658 1 NC_012759.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4352658 aidB 7955617 aidB Escherichia coli BW2952 isovaleryl CoA dehydrogenase YP_002929090.1 4351033 D 595496 CDS YP_002929091.1 238903295 7954057 complement(4352775..4353050) 1 NC_012759.1 MG1655 equivalent: b4188; hypothetical protein 4353050 yjfN 7954057 yjfN Escherichia coli BW2952 hypothetical protein YP_002929091.1 4352775 R 595496 CDS YP_002929092.1 238903296 7955427 complement(4353199..4353528) 1 NC_012759.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A 4353528 yjfO 7955427 yjfO Escherichia coli BW2952 putative biofilm stress and motility protein A YP_002929092.1 4353199 R 595496 CDS YP_002929093.1 238903297 7952898 4353710..4354459 1 NC_012759.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4354459 yjfP 7952898 yjfP Escherichia coli BW2952 esterase YP_002929093.1 4353710 D 595496 CDS YP_002929094.1 238903298 7954975 complement(4354456..4355211) 1 NC_012759.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4355211 ulaR 7954975 ulaR Escherichia coli BW2952 transcriptional repressor UlaR YP_002929094.1 4354456 R 595496 CDS YP_002929095.1 238903299 7953417 complement(4355319..4356383) 1 NC_012759.1 MG1655 equivalent: b4192; putative L-ascorbate 6-phosphate lactonase 4356383 ulaG 7953417 ulaG Escherichia coli BW2952 putative L-ascorbate 6-phosphate lactonase YP_002929095.1 4355319 R 595496 CDS YP_002929096.1 238903300 7955099 4356738..4358135 1 NC_012759.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4358135 ulaA 7955099 ulaA Escherichia coli BW2952 PTS system ascorbate-specific transporter subunit IIC YP_002929096.1 4356738 D 595496 CDS YP_002929097.1 238903301 7954119 4358151..4358456 1 NC_012759.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4358456 ulaB 7954119 ulaB Escherichia coli BW2952 PTS system L-ascorbate-specific transporter subunit IIB YP_002929097.1 4358151 D 595496 CDS YP_002929098.1 238903302 7954118 4358466..4358930 1 NC_012759.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4358930 ulaC 7954118 ulaC Escherichia coli BW2952 PTS system L-ascorbate-specific transporter subunit IIA YP_002929098.1 4358466 D 595496 CDS YP_002929099.1 238903303 7954117 4358944..4359594 1 NC_012759.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4359594 ulaD 7954117 ulaD Escherichia coli BW2952 3-keto-L-gulonate-6-phosphate decarboxylase YP_002929099.1 4358944 D 595496 CDS YP_002929100.1 238903304 7952310 4359604..4360458 1 NC_012759.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4360458 ulaE 7952310 ulaE Escherichia coli BW2952 L-xylulose 5-phosphate 3-epimerase YP_002929100.1 4359604 D 595496 CDS YP_002929101.1 238903305 7954177 4360458..4361144 1 NC_012759.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4361144 sgaE 7954177 sgaE Escherichia coli BW2952 L-ribulose-5-phosphate 4-epimerase YP_002929101.1 4360458 D 595496 CDS YP_002929102.1 238903306 7954168 complement(4361274..4361549) 1 NC_012759.1 MG1655 equivalent: b4199; hypothetical protein 4361549 yjfY 7954168 yjfY Escherichia coli BW2952 hypothetical protein YP_002929102.1 4361274 R 595496 CDS YP_002929103.1 238903307 7955428 4361876..4362271 1 NC_012759.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4362271 rpsF 7955428 rpsF Escherichia coli BW2952 30S ribosomal protein S6 YP_002929103.1 4361876 D 595496 CDS YP_002929104.1 238903308 7952290 4362278..4362592 1 NC_012759.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4362592 priB 7952290 priB Escherichia coli BW2952 primosomal replication protein N YP_002929104.1 4362278 D 595496 CDS YP_002929105.1 238903309 7955764 4362597..4362824 1 NC_012759.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4362824 rpsR 7955764 rpsR Escherichia coli BW2952 30S ribosomal protein S18 YP_002929105.1 4362597 D 595496 CDS YP_002929106.1 238903310 7952281 4362866..4363315 1 NC_012759.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4363315 rplI 7952281 rplI Escherichia coli BW2952 50S ribosomal protein L9 YP_002929106.1 4362866 D 595496 CDS YP_002929107.1 238903311 7952369 complement(4363386..4364180) 1 NC_012759.1 MG1655 equivalent: b4204; hypothetical protein 4364180 yjfZ 7952369 yjfZ Escherichia coli BW2952 hypothetical protein YP_002929107.1 4363386 R 595496 CDS YP_002929108.1 238903312 7955429 complement(4364837..4365475) 1 NC_012759.1 MG1655 equivalent: b4206; putative cell envelope opacity-associated protein 4365475 ytfB 7955429 ytfB Escherichia coli BW2952 putative cell envelope opacity-associated protein YP_002929108.1 4364837 R 595496 CDS YP_002929109.1 238903313 7954686 4365693..4366313 1 NC_012759.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4366313 fklB 7954686 fklB Escherichia coli BW2952 peptidyl-prolyl cis-trans isomerase YP_002929109.1 4365693 D 595496 CDS YP_002929110.1 238903314 7953581 4366622..4368034 1 NC_012759.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4368034 cycA 7953581 cycA Escherichia coli BW2952 D-alanine/D-serine/glycine permease YP_002929110.1 4366622 D 595496 CDS YP_002929111.1 238903315 7953214 complement(4368079..4368741) 1 NC_012759.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4368741 ytfE 7953214 ytfE Escherichia coli BW2952 iron-sulfur cluster repair di-iron protein YP_002929111.1 4368079 R 595496 CDS YP_002929112.1 238903316 7955563 complement(4368849..4369823) 1 NC_012759.1 MG1655 equivalent: b4210; putative inner membrane protein 4369823 ytfF 7955563 ytfF Escherichia coli BW2952 putative inner membrane protein YP_002929112.1 4368849 R 595496 CDS YP_002929113.1 238903317 7955017 complement(4369922..4370782) 1 NC_012759.1 MG1655 equivalent: b4211; NAD(P)H:quinone oxidoreductase 4370782 ytfG 7955017 ytfG Escherichia coli BW2952 NAD(P)H:quinone oxidoreductase YP_002929113.1 4369922 R 595496 CDS YP_002929114.1 238903318 7954351 4370871..4371251 1 NC_012759.1 MG1655 equivalent: b4212; putative transcriptional regulator 4371251 ytfH 7954351 ytfH Escherichia coli BW2952 putative transcriptional regulator YP_002929114.1 4370871 D 595496 CDS YP_002929115.1 238903319 7955640 complement(4371380..4373323) 1 NC_012759.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4373323 cpdB 7955640 cpdB Escherichia coli BW2952 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_002929115.1 4371380 R 595496 CDS YP_002929116.1 238903320 7952240 4373513..4374253 1 NC_012759.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4374253 cysQ 7952240 cysQ Escherichia coli BW2952 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_002929116.1 4373513 D 595496 CDS YP_002929117.1 238903321 7954467 4374465..4375403 1 NC_012759.1 MG1655 equivalent: b4215; hypothetical protein 4375403 ytfI 7954467 ytfI Escherichia coli BW2952 hypothetical protein YP_002929117.1 4374465 D 595496 CDS YP_002929118.1 238903322 7955524 complement(4375466..4376020) 1 NC_012759.1 MG1655 equivalent: b4216; putative transcriptional regulator 4376020 ytfJ 7955524 ytfJ Escherichia coli BW2952 putative transcriptional regulator YP_002929118.1 4375466 R 595496 CDS YP_002929119.1 238903323 7955632 4376345..4376551 1 NC_012759.1 MG1655 equivalent: b4217; hypothetical protein 4376551 ytfK 7955632 ytfK Escherichia coli BW2952 hypothetical protein YP_002929119.1 4376345 D 595496 CDS YP_002929120.1 238903324 7953062 complement(4376630..4377973) 1 NC_012759.1 MG1655 equivalent: b4218; putative inner membrane protein 4377973 ytfL 7953062 ytfL Escherichia coli BW2952 putative inner membrane protein YP_002929120.1 4376630 R 595496 CDS YP_002929121.1 238903325 7955018 complement(4378296..4378934) 1 NC_012759.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4378934 msrA 7955018 msrA Escherichia coli BW2952 methionine sulfoxide reductase A YP_002929121.1 4378296 R 595496 CDS YP_002929122.1 238903326 7954245 4379140..4380873 1 NC_012759.1 MG1655 equivalent: b4220; putative outer membrane protein and surface antigen 4380873 ytfM 7954245 ytfM Escherichia coli BW2952 putative outer membrane protein and surface antigen YP_002929122.1 4379140 D 595496 CDS YP_002929123.1 238903327 7955216 4380870..4384649 1 NC_012759.1 MG1655 equivalent: b4221; hypothetical protein 4384649 ytfN 7955216 ytfN Escherichia coli BW2952 hypothetical protein YP_002929123.1 4380870 D 595496 CDS YP_002929124.1 238903328 7953063 4384652..4384993 1 NC_012759.1 MG1655 equivalent: b4222; hypothetical protein 4384993 ytfP 7953063 ytfP Escherichia coli BW2952 hypothetical protein YP_002929124.1 4384652 D 595496 CDS YP_002929125.1 238903329 7953064 4385205..4385456 1 NC_012759.1 part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 4385456 chpS 7953064 chpS Escherichia coli BW2952 antitoxin ChpS YP_002929125.1 4385205 D 595496 CDS YP_002929126.1 238903330 7952487 4385450..4385800 1 NC_012759.1 toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 4385800 chpB 7952487 chpB Escherichia coli BW2952 toxin ChpB YP_002929126.1 4385450 D 595496 CDS YP_002929127.1 238903331 7956161 complement(4385880..4386410) 1 NC_012759.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4386410 ppa 7956161 ppa Escherichia coli BW2952 inorganic pyrophosphatase YP_002929127.1 4385880 R 595496 CDS YP_002929128.1 238903332 7953999 4386720..4387676 1 NC_012759.1 MG1655 equivalent: b4227; putative sugar transporter subunit: periplasmic-binding component of ABC superfamily 4387676 ytfQ 7953999 ytfQ Escherichia coli BW2952 putative sugar transporter subunit: periplasmic-binding component of ABC superfamily YP_002929128.1 4386720 D 595496 CDS YP_002929129.1 238903333 7955611 4387816..4389318 1 NC_012759.1 MG1655 equivalent: b4485; putative sugar transporter subunit: ATP-binding component of ABC superfamily 4389318 ytfR 7955611 ytfR Escherichia coli BW2952 putative sugar transporter subunit: ATP-binding component of ABC superfamily YP_002929129.1 4387816 D 595496 CDS YP_002929130.1 238903334 7955612 4389329..4390354 1 NC_012759.1 MG1655 equivalent: b4230; putative sugar transporter subunit: membrane component of ABC superfamily 4390354 ytfT 7955612 ytfT Escherichia coli BW2952 putative sugar transporter subunit: membrane component of ABC superfamily YP_002929130.1 4389329 D 595496 CDS YP_002929131.1 238903335 7955614 4390341..4391336 1 NC_012759.1 membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4391336 yjfF 7955614 yjfF Escherichia coli BW2952 inner membrane ABC transporter permease YjfF YP_002929131.1 4390341 D 595496 CDS YP_002929132.1 238903336 7955608 complement(4391369..4392367) 1 NC_012759.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4392367 fbp 7955608 fbp Escherichia coli BW2952 fructose-1,6-bisphosphatase YP_002929132.1 4391369 R 595496 CDS YP_002929133.1 238903337 7953634 4392543..4393916 1 NC_012759.1 MG1655 equivalent: b4233; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4393916 mpl 7953634 mpl Escherichia coli BW2952 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002929133.1 4392543 D 595496 CDS YP_002929134.1 238903338 7956242 complement(4394072..4394623) 1 NC_012759.1 MG1655 equivalent: b4234; hypothetical protein 4394623 yjgA 7956242 yjgA Escherichia coli BW2952 hypothetical protein YP_002929134.1 4394072 R 595496 CDS YP_002929135.1 238903339 7952899 4394717..4396069 1 NC_012759.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4396069 pmbA 7952899 pmbA Escherichia coli BW2952 peptidase PmbA YP_002929135.1 4394717 D 595496 CDS YP_002929136.1 238903340 7955288 complement(4396658..4397122) 1 NC_012759.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4397122 nrdG 7955288 nrdG Escherichia coli BW2952 anaerobic ribonucleotide reductase-activating protein YP_002929136.1 4396658 R 595496 CDS YP_002929137.1 238903341 7952479 complement(4397280..4399418) 1 NC_012759.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4399418 nrdD 7952479 nrdD Escherichia coli BW2952 anaerobic ribonucleoside triphosphate reductase YP_002929137.1 4397280 R 595496 CDS YP_002929138.1 238903342 7952478 complement(4399812..4401467) 1 NC_012759.1 MG1655 equivalent: b4239; trehalose-6-phosphate hydrolase 4401467 treC 7952478 treC Escherichia coli BW2952 trehalose-6-phosphate hydrolase YP_002929138.1 4399812 R 595496 CDS YP_002929139.1 238903343 7956187 complement(4401517..4402938) 1 NC_012759.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4402938 treB 7956187 treB Escherichia coli BW2952 PTS system trehalose(maltose)-specific transporter subunit IIBC YP_002929139.1 4401517 R 595496 CDS YP_002929140.1 238903344 7953749 complement(4403057..4404004) 1 NC_012759.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4404004 treR 7953749 treR Escherichia coli BW2952 trehalose repressor YP_002929140.1 4403057 R 595496 CDS YP_002929141.1 238903345 7953460 4404383..4407079 1 NC_012759.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4407079 mgtA 7953460 mgtA Escherichia coli BW2952 magnesium-transporting ATPase MgtA YP_002929141.1 4404383 D 595496 CDS YP_002929142.1 238903346 7954191 complement(4407285..4407671) 1 NC_012759.1 MG1655 equivalent: b4243; ketoacid-binding protein 4407671 yjgF 7954191 yjgF Escherichia coli BW2952 ketoacid-binding protein YP_002929142.1 4407285 R 595496 CDS YP_002929143.1 238903347 7954058 complement(4407744..4408205) 1 NC_012759.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4408205 pyrI 7954058 pyrI Escherichia coli BW2952 aspartate carbamoyltransferase regulatory subunit YP_002929143.1 4407744 R 595496 CDS YP_002929144.1 238903348 7952514 complement(4408218..4409153) 1 NC_012759.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4409153 pyrB 7952514 pyrB Escherichia coli BW2952 aspartate carbamoyltransferase catalytic subunit YP_002929144.1 4408218 R 595496 CDS YP_002929145.1 238903349 7952513 complement(4409157..4409291) 1 NC_012759.1 MG1655 equivalent: b4246; pyrBI operon leader peptide 4409291 pyrL 7952513 pyrL Escherichia coli BW2952 pyrBI operon leader peptide YP_002929145.1 4409157 R 595496 CDS YP_002929146.1 238903350 7955834 complement(4409572..4409967) 1 NC_012759.1 MG1655 equivalent: b4248; putative mRNA endoribonuclease 4409967 yjgH 7955834 yjgH Escherichia coli BW2952 putative mRNA endoribonuclease YP_002929146.1 4409572 R 595496 CDS YP_002929147.1 238903351 7955166 complement(4410098..4410811) 1 NC_012759.1 MG1655 equivalent: b4249; oxidoreductase 4410811 yjgI 7955166 yjgI Escherichia coli BW2952 oxidoreductase YP_002929147.1 4410098 R 595496 CDS YP_002929148.1 238903352 7955249 4410882..4411475 1 NC_012759.1 MG1655 equivalent: b4251; putative transcriptional regulator 4411475 yjgJ 7955249 yjgJ Escherichia coli BW2952 putative transcriptional regulator YP_002929148.1 4410882 D 595496 CDS YP_002929149.1 238903353 7955641 4411620..4412072 1 NC_012759.1 MG1655 equivalent: b4252; hypothetical protein 4412072 yjgK 7955641 yjgK Escherichia coli BW2952 hypothetical protein YP_002929149.1 4411620 D 595496 CDS YP_002929150.1 238903354 7953065 4412195..4414009 1 NC_012759.1 MG1655 equivalent: b4253; hypothetical protein 4414009 yjgL 7953065 yjgL Escherichia coli BW2952 hypothetical protein YP_002929150.1 4412195 D 595496 CDS YP_002929151.1 238903355 7955525 complement(4414065..4415069) 1 NC_012759.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 4415069 argI 7955525 argI Escherichia coli BW2952 ornithine carbamoyltransferase subunit I YP_002929151.1 4414065 R 595496 CDS YP_002929152.1 238903356 7954428 4415231..4415647 1 NC_012759.1 MG1655 equivalent: b4255; hypothetical protein 4415647 rraB 7954428 rraB Escherichia coli BW2952 hypothetical protein YP_002929152.1 4415231 D 595496 CDS YP_002929153.1 238903357 7953066 complement(4415792..4416295) 1 NC_012759.1 MG1655 equivalent: b4256; putative acetyltransferase 4416295 yjgM 7953066 yjgM Escherichia coli BW2952 putative acetyltransferase YP_002929153.1 4415792 R 595496 CDS YP_002929154.1 238903358 7954602 4416488..4417684 1 NC_012759.1 MG1655 equivalent: b4257; hypothetical protein 4417684 yjgN 7954602 yjgN Escherichia coli BW2952 hypothetical protein YP_002929154.1 4416488 D 595496 CDS YP_002929155.1 238903359 7952737 complement(4417740..4420595) 1 NC_012759.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4420595 valS 7952737 valS Escherichia coli BW2952 valyl-tRNA synthetase YP_002929155.1 4417740 R 595496 CDS YP_002929156.1 238903360 7956270 complement(4420595..4421038) 1 NC_012759.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4421038 holC 7956270 holC Escherichia coli BW2952 DNA polymerase III subunit chi YP_002929156.1 4420595 R 595496 CDS YP_002929157.1 238903361 7953321 complement(4421198..4422709) 1 NC_012759.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4422709 pepA 7953321 pepA Escherichia coli BW2952 leucyl aminopeptidase YP_002929157.1 4421198 R 595496 CDS YP_002929158.1 238903362 7952470 4422976..4424076 1 NC_012759.1 MG1655 equivalent: b4261; hypothetical protein 4424076 yjgP 7952470 yjgP Escherichia coli BW2952 hypothetical protein YP_002929158.1 4422976 D 595496 CDS YP_002929159.1 238903363 7952738 4424076..4425158 1 NC_012759.1 MG1655 equivalent: b4262; hypothetical protein 4425158 yjgQ 7952738 yjgQ Escherichia coli BW2952 hypothetical protein YP_002929159.1 4424076 D 595496 CDS YP_002929160.1 238903364 7952739 complement(4425319..4426821) 1 NC_012759.1 MG1655 equivalent: b4263; putative ATPase 4426821 yjgR 7952739 yjgR Escherichia coli BW2952 putative ATPase YP_002929160.1 4425319 R 595496 CDS YP_002929161.1 238903365 7954661 complement(4426899..4427897) 1 NC_012759.1 MG1655 equivalent: b4264; DNA-binding transcriptional repressor, 5-gluconate-binding 4427897 idnR 7954661 idnR Escherichia coli BW2952 DNA-binding transcriptional repressor, 5-gluconate-binding YP_002929161.1 4426899 R 595496 CDS YP_002929162.1 238903366 7953477 complement(4427964..4429283) 1 NC_012759.1 MG1655 equivalent: b4265; L-idonate and D-gluconate transporter 4429283 idnT 7953477 idnT Escherichia coli BW2952 L-idonate and D-gluconate transporter YP_002929162.1 4427964 R 595496 CDS YP_002929163.1 238903367 7954143 complement(4429345..4430109) 1 NC_012759.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 4430109 idnO 7954143 idnO Escherichia coli BW2952 gluconate 5-dehydrogenase YP_002929163.1 4429345 R 595496 CDS YP_002929164.1 238903368 7952371 complement(4430133..4431164) 1 NC_012759.1 NAD-binding; L-idonate 5-dehydrogenase 4431164 idnD 7952371 idnD Escherichia coli BW2952 L-idonate 5-dehydrogenase YP_002929164.1 4430133 R 595496 CDS YP_002929165.1 238903369 7954142 4431381..4431944 1 NC_012759.1 MG1655 equivalent: b4268; D-gluconate kinase 4431944 idnK 7954142 idnK Escherichia coli BW2952 D-gluconate kinase YP_002929165.1 4431381 D 595496 CDS YP_002929166.1 238903370 7953244 complement(4431948..4432967) 1 NC_012759.1 MG1655 equivalent: b4269; putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding 4432967 yjgB 7953244 yjgB Escherichia coli BW2952 putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding YP_002929166.1 4431948 R 595496 CDS YP_002929167.1 238903371 7952166 4435030..4435395 1 NC_012759.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 4435395 insC 7952166 insC Escherichia coli BW2952 insertion sequence 2 OrfA protein YP_002929167.1 4435030 D 595496 CDS YP_002929168.1 238903372 7954076 4435353..4436258 1 NC_012759.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 4436258 insD 7954076 insD Escherichia coli BW2952 insertion element IS2 transposase InsD YP_002929168.1 4435353 D 595496 CDS YP_002929169.1 238903373 7954082 4438018..4438347 1 NC_012759.1 MG1655 equivalent: b4277; KpLE2 phage protein 4438347 yjgZ 7954082 yjgZ Escherichia coli BW2952 KpLE2 phage protein YP_002929169.1 4438018 D 595496 CDS YP_002929170.1 238903374 7954100 complement(4438861..4440189) 1 NC_012759.1 MG1655 equivalent: b4278; KpLE2 phage-like element; IS4 putative transposase 4440189 insG 7954100 insG Escherichia coli BW2952 KpLE2 phage-like element; IS4 putative transposase YP_002929170.1 4438861 R 595496 CDS YP_002929171.1 238903375 7954086 4440816..4442033 1 NC_012759.1 MG1655 equivalent: b4279; putative sialic acid transporter 4442033 yjhB 7954086 yjhB Escherichia coli BW2952 putative sialic acid transporter YP_002929171.1 4440816 D 595496 CDS YP_002929172.1 238903376 7954102 4442045..4443163 1 NC_012759.1 MG1655 equivalent: b4280; KpLE2 phage-like element; putative oxidoreductase 4443163 yjhC 7954102 yjhC Escherichia coli BW2952 KpLE2 phage-like element; putative oxidoreductase YP_002929172.1 4442045 D 595496 CDS YP_002929173.1 238903377 7954097 4443206..4443331 1 NC_012759.1 MG1655 equivalent: b4655; hypothetical protein 4443331 ythA 7954097 ythA Escherichia coli BW2952 hypothetical protein YP_002929173.1 4443206 D 595496 CDS YP_002929174.1 238903378 7953552 complement(4444224..4445375) 1 NC_012759.1 MG1655 equivalent: b4284; KpLE2 phage-like element; IS30 transposase 4445375 insI 7953552 insI Escherichia coli BW2952 KpLE2 phage-like element; IS30 transposase YP_002929174.1 4444224 R 595496 CDS YP_002929175.1 238903379 7954083 complement(4447448..4448215) 1 NC_012759.1 Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit 4448215 fecE 7954083 fecE Escherichia coli BW2952 iron-dicitrate transporter ATP-binding subunit YP_002929175.1 4447448 R 595496 CDS YP_002929176.1 238903380 7954063 complement(4448216..4449172) 1 NC_012759.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD 4449172 fecD 7954063 fecD Escherichia coli BW2952 iron-dicitrate transporter subunit FecD YP_002929176.1 4448216 R 595496 CDS YP_002929177.1 238903381 7954064 complement(4449169..4450167) 1 NC_012759.1 part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease subunit 4450167 fecC 7954064 fecC Escherichia coli BW2952 iron-dicitrate transporter permease subunit YP_002929177.1 4449169 R 595496 CDS YP_002929178.1 238903382 7954065 complement(4450164..4451066) 1 NC_012759.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit 4451066 fecB 7954065 fecB Escherichia coli BW2952 iron-dicitrate transporter substrate-binding subunit YP_002929178.1 4450164 R 595496 CDS YP_002929179.1 238903383 7954066 complement(4451111..4453435) 1 NC_012759.1 MG1655 equivalent: b4291; KpLE2 phage-like element; ferric citrate outer membrane transporter 4453435 fecA 7954066 fecA Escherichia coli BW2952 KpLE2 phage-like element; ferric citrate outer membrane transporter YP_002929179.1 4451111 R 595496 CDS YP_002929180.1 238903384 7954062 complement(4453522..4454475) 1 NC_012759.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR 4454475 fecR 7954062 fecR Escherichia coli BW2952 fec operon regulator FecR YP_002929180.1 4453522 R 595496 CDS YP_002929181.1 238903385 7954104 complement(4454472..4454993) 1 NC_012759.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI 4454993 fecI 7954104 fecI Escherichia coli BW2952 RNA polymerase sigma factor FecI YP_002929181.1 4454472 R 595496 CDS YP_002929182.1 238903386 7954103 4455285..4455560 1 NC_012759.1 MG1655 equivalent: b4294; KpLE2 phage-like element; IS1 repressor protein InsA 4455560 insA 7954103 insA Escherichia coli BW2952 KpLE2 phage-like element; IS1 repressor protein InsA YP_002929182.1 4455285 D 595496 CDS YP_002929183.1 238903387 7954069 complement(4456096..4457082) 1 NC_012759.1 MG1655 equivalent: b4295; KpLE2 phage-like element; putative DNA-binding transcriptional regulator 4457082 yjhU 7954069 yjhU Escherichia coli BW2952 KpLE2 phage-like element; putative DNA-binding transcriptional regulator YP_002929183.1 4456096 R 595496 CDS YP_002929184.1 238903388 7954089 complement(4457429..4458778) 1 NC_012759.1 MG1655 equivalent: b4296; KpLE2 phage-like element; putative transporter 4458778 yjhF 7954089 yjhF Escherichia coli BW2952 KpLE2 phage-like element; putative transporter YP_002929184.1 4457429 R 595496 CDS YP_002929185.1 238903389 7954101 complement(4458885..4460852) 1 NC_012759.1 MG1655 equivalent: b4297; hypothetical protein 4460852 yjhG 7954101 yjhG Escherichia coli BW2952 hypothetical protein YP_002929185.1 4458885 R 595496 CDS YP_002929186.1 238903390 7954088 complement(4460863..4461768) 1 NC_012759.1 MG1655 equivalent: b4298; KpLE2 phage-like element; putative lyase/synthase 4461768 yjhH 7954088 yjhH Escherichia coli BW2952 KpLE2 phage-like element; putative lyase/synthase YP_002929186.1 4460863 R 595496 CDS YP_002929187.1 238903391 7954094 complement(4461773..4462561) 1 NC_012759.1 MG1655 equivalent: b4299; KpLE2 phage-like element; putative DNA-binding transcriptional regulator 4462561 yjhI 7954094 yjhI Escherichia coli BW2952 KpLE2 phage-like element; putative DNA-binding transcriptional regulator YP_002929187.1 4461773 R 595496 CDS YP_002929188.1 238903392 7954090 complement(4462864..4463646) 1 NC_012759.1 MG1655 equivalent: b4300; KpLE2 phage-like element; putative DNA-binding transcriptional regulator 4463646 sgcR 7954090 sgcR Escherichia coli BW2952 KpLE2 phage-like element; putative DNA-binding transcriptional regulator YP_002929188.1 4462864 R 595496 CDS YP_002929189.1 238903393 7954091 complement(4463663..4464295) 1 NC_012759.1 MG1655 equivalent: b4301; epimerase 4464295 sgcE 7954091 sgcE Escherichia coli BW2952 epimerase YP_002929189.1 4463663 R 595496 CDS YP_002929190.1 238903394 7954093 complement(4464307..4464738) 1 NC_012759.1 MG1655 equivalent: b4302; KpLE2 phage-like element; putative phosphotransferase enzyme IIA component 4464738 sgcA 7954093 sgcA Escherichia coli BW2952 KpLE2 phage-like element; putative phosphotransferase enzyme IIA component YP_002929190.1 4464307 R 595496 CDS YP_002929191.1 238903395 7952201 complement(4464869..4465675) 1 NC_012759.1 MG1655 equivalent: b4303; KpLE2 phage-like element; putative nucleoside triphosphatase 4465675 sgcQ 7952201 sgcQ Escherichia coli BW2952 KpLE2 phage-like element; putative nucleoside triphosphatase YP_002929191.1 4464869 R 595496 CDS YP_002929192.1 238903396 7954096 complement(4465688..4467001) 1 NC_012759.1 MG1655 equivalent: b4304; KpLE2 phage-like element; putative phosphotransferase enzyme IIC component 4467001 sgcC 7954096 sgcC Escherichia coli BW2952 KpLE2 phage-like element; putative phosphotransferase enzyme IIC component YP_002929192.1 4465688 R 595496 CDS YP_002929193.1 238903397 7954099 complement(4467013..4467291) 1 NC_012759.1 MG1655 equivalent: b4565; putative enzyme IIB component of PTS 4467291 sgcB 7954099 sgcB Escherichia coli BW2952 putative enzyme IIB component of PTS YP_002929193.1 4467013 R 595496 CDS YP_002929194.1 238903398 7954853 complement(4467288..4468409) 1 NC_012759.1 MG1655 equivalent: b4305; putative endoglucanase with Zn-dependent exopeptidase domain protein 4468409 sgcX 7954853 sgcX Escherichia coli BW2952 putative endoglucanase with Zn-dependent exopeptidase domain protein YP_002929194.1 4467288 R 595496 CDS YP_002929195.1 238903399 7954092 complement(4469195..4469941) 1 NC_012759.1 MG1655 equivalent: b4306; KpLE2 phage-like element; putative methyltransferase 4469941 yjhP 7954092 yjhP Escherichia coli BW2952 KpLE2 phage-like element; putative methyltransferase YP_002929195.1 4469195 R 595496 CDS YP_002929196.1 238903400 7954095 complement(4469997..4470542) 1 NC_012759.1 MG1655 equivalent: b4307; KpLE2 phage-like element; putative acetyltransferase 4470542 yjhQ 7954095 yjhQ Escherichia coli BW2952 KpLE2 phage-like element; putative acetyltransferase YP_002929196.1 4469997 R 595496 CDS YP_002929197.1 238903401 7954087 complement(4470554..4470811) 1 NC_012759.1 MG1655 equivalent: b4566; hypothetical protein 4470811 yjhX 7954087 yjhX Escherichia coli BW2952 hypothetical protein YP_002929197.1 4470554 R 595496 CDS YP_002929198.1 238903402 7952913 complement(4473372..4474352) 1 NC_012759.1 MG1655 equivalent: b4309; hypothetical protein 4474352 yjhS 7952913 yjhS Escherichia coli BW2952 hypothetical protein YP_002929198.1 4473372 R 595496 CDS YP_002929199.1 238903403 7952900 complement(4474417..4475523) 1 NC_012759.1 MG1655 equivalent: b4310; N-acetylneuraminic acid mutarotase 4475523 nanM 7952900 nanM Escherichia coli BW2952 N-acetylneuraminic acid mutarotase YP_002929199.1 4474417 R 595496 CDS YP_002929200.1 238903404 7952901 complement(4475543..4476259) 1 NC_012759.1 MG1655 equivalent: b4311; N-acetylnuraminic acid outer membrane channel protein 4476259 nanC 7952901 nanC Escherichia coli BW2952 N-acetylnuraminic acid outer membrane channel protein YP_002929200.1 4475543 R 595496 CDS YP_002929201.1 238903405 7954347 4478031..4478534 1 NC_012759.1 Insertion element IS1 1/5/6 protein insB 4478534 7954347 BWG_4010 Escherichia coli BW2952 Insertion element IS1 1/5/6 protein insB YP_002929201.1 4478031 D 595496 CDS YP_002929202.1 238903406 7954004 4478536..4479141 1 NC_012759.1 inversion of on/off regulator of fimA; tyrosine recombinase 4479141 fimE 7954004 fimE Escherichia coli BW2952 tyrosine recombinase YP_002929202.1 4478536 D 595496 CDS YP_002929203.1 238903407 7956222 4479623..4480171 1 NC_012759.1 MG1655 equivalent: b4314; major type 1 subunit fimbrin (pilin) 4480171 fimA 7956222 fimA Escherichia coli BW2952 major type 1 subunit fimbrin (pilin) YP_002929203.1 4479623 D 595496 CDS YP_002929204.1 238903408 7954196 4480236..4480775 1 NC_012759.1 MG1655 equivalent: b4315; type 1 pilus biosynthesis fimbrial protein 4480775 fimI 7954196 fimI Escherichia coli BW2952 type 1 pilus biosynthesis fimbrial protein YP_002929204.1 4480236 D 595496 CDS YP_002929205.1 238903409 7953577 4480812..4481537 1 NC_012759.1 MG1655 equivalent: b4316; chaperone, periplasmic 4481537 fimC 7953577 fimC Escherichia coli BW2952 chaperone, periplasmic YP_002929205.1 4480812 D 595496 CDS YP_002929206.1 238903410 7952630 4481604..4484240 1 NC_012759.1 MG1655 equivalent: b4317; outer membrane usher protein, type 1 fimbrial synthesis 4484240 fimD 7952630 fimD Escherichia coli BW2952 outer membrane usher protein, type 1 fimbrial synthesis YP_002929206.1 4481604 D 595496 CDS YP_002929207.1 238903411 7954451 4484250..4484780 1 NC_012759.1 MG1655 equivalent: b4318; minor component of type 1 fimbriae 4484780 fimF 7954451 fimF Escherichia coli BW2952 minor component of type 1 fimbriae YP_002929207.1 4484250 D 595496 CDS YP_002929208.1 238903412 7954264 4484793..4485296 1 NC_012759.1 MG1655 equivalent: b4319; minor component of type 1 fimbriae 4485296 fimG 7954264 fimG Escherichia coli BW2952 minor component of type 1 fimbriae YP_002929208.1 4484793 D 595496 CDS YP_002929209.1 238903413 7954265 4485316..4486218 1 NC_012759.1 MG1655 equivalent: b4320; minor component of type 1 fimbriae 4486218 fimH 7954265 fimH Escherichia coli BW2952 minor component of type 1 fimbriae YP_002929209.1 4485316 D 595496 CDS YP_002929210.1 238903414 7954266 complement(4486461..4487804) 1 NC_012759.1 MG1655 equivalent: b4321; fructuronate transporter 4487804 gntP 7954266 gntP Escherichia coli BW2952 fructuronate transporter YP_002929210.1 4486461 R 595496 CDS YP_002929211.1 238903415 7953641 4488144..4489328 1 NC_012759.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4489328 uxuA 7953641 uxuA Escherichia coli BW2952 mannonate dehydratase YP_002929211.1 4488144 D 595496 CDS YP_002929212.1 238903416 7954213 4489409..4490869 1 NC_012759.1 MG1655 equivalent: b4323; D-mannonate oxidoreductase, NAD-binding 4490869 uxuB 7954213 uxuB Escherichia coli BW2952 D-mannonate oxidoreductase, NAD-binding YP_002929212.1 4489409 D 595496 CDS YP_002929213.1 238903417 7953297 4491084..4491857 1 NC_012759.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4491857 uxuR 7953297 uxuR Escherichia coli BW2952 DNA-binding transcriptional repressor UxuR YP_002929213.1 4491084 D 595496 CDS YP_002929214.1 238903418 7953471 complement(4491998..4492828) 1 NC_012759.1 MG1655 equivalent: b4325; hypothetical protein 4492828 yjiC 7953471 yjiC Escherichia coli BW2952 hypothetical protein YP_002929214.1 4491998 R 595496 CDS YP_002929215.1 238903419 7955430 4493501..4493893 1 NC_012759.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4493893 iraD 7955430 iraD Escherichia coli BW2952 DNA replication/recombination/repair protein YP_002929215.1 4493501 D 595496 CDS YP_002929216.1 238903420 7953331 complement(4493886..4494797) 1 NC_012759.1 MG1655 equivalent: b4327; putative DNA-binding transcriptional regulator 4494797 yjiE 7953331 yjiE Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002929216.1 4493886 R 595496 CDS YP_002929217.1 238903421 7954786 complement(4494862..4496034) 1 NC_012759.1 MG1655 equivalent: b4328; isoaspartyl dipeptidase 4496034 iadA 7954786 iadA Escherichia coli BW2952 isoaspartyl dipeptidase YP_002929217.1 4494862 R 595496 CDS YP_002929218.1 238903422 7954047 complement(4496047..4496508) 1 NC_012759.1 MG1655 equivalent: b4329; hypothetical protein 4496508 yjiG 7954047 yjiG Escherichia coli BW2952 hypothetical protein YP_002929218.1 4496047 R 595496 CDS YP_002929219.1 238903423 7952694 complement(4496505..4497188) 1 NC_012759.1 MG1655 equivalent: b4330; hypothetical protein 4497188 yjiH 7952694 yjiH Escherichia coli BW2952 hypothetical protein YP_002929219.1 4496505 R 595496 CDS YP_002929220.1 238903424 7952695 4497438..4497992 1 NC_012759.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4497992 kptA 7952695 kptA Escherichia coli BW2952 RNA 2'-phosphotransferase-like protein YP_002929220.1 4497438 D 595496 CDS YP_002929221.1 238903425 7952270 complement(4498005..4499183) 1 NC_012759.1 MG1655 equivalent: b4332; putative inner membrane protein 4499183 yjiJ 7952270 yjiJ Escherichia coli BW2952 putative inner membrane protein YP_002929221.1 4498005 R 595496 CDS YP_002929222.1 238903426 7955019 complement(4499251..4500111) 1 NC_012759.1 MG1655 equivalent: b4333; hypothetical protein 4500111 yjiK 7955019 yjiK Escherichia coli BW2952 hypothetical protein YP_002929222.1 4499251 R 595496 CDS YP_002929223.1 238903427 7952902 complement(4500429..4501196) 1 NC_012759.1 MG1655 equivalent: b4334; putative ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase 4501196 yjiL 7952902 yjiL Escherichia coli BW2952 putative ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase YP_002929223.1 4500429 R 595496 CDS YP_002929224.1 238903428 7954662 complement(4501206..4502357) 1 NC_012759.1 MG1655 equivalent: b4335; putative 2-hydroxyglutaryl-CoA dehydratase 4502357 yjiM 7954662 yjiM Escherichia coli BW2952 putative 2-hydroxyglutaryl-CoA dehydratase YP_002929224.1 4501206 R 595496 CDS YP_002929225.1 238903429 7954587 complement(4502473..4503753) 1 NC_012759.1 MG1655 equivalent: b4336; hypothetical protein 4503753 yjiN 7954587 yjiN Escherichia coli BW2952 hypothetical protein YP_002929225.1 4502473 R 595496 CDS YP_002929226.1 238903430 7952696 complement(4503794..4505026) 1 NC_012759.1 MG1655 equivalent: b4337; multidrug efflux system protein 4505026 mdtM 7952696 mdtM Escherichia coli BW2952 multidrug efflux system protein YP_002929226.1 4503794 R 595496 CDS YP_002929227.1 238903431 7954300 complement(4506669..4508081) 1 NC_012759.1 MG1655 equivalent: b4340; fused putative DNA-binding transcriptional regulator/putative aminotransferase 4508081 yjiR 7954300 yjiR Escherichia coli BW2952 fused putative DNA-binding transcriptional regulator/putative aminotransferase YP_002929227.1 4506669 R 595496 CDS YP_002929228.1 238903432 7953712 4508258..4508422 1 NC_012759.1 MG1655 equivalent: b4341; hypothetical protein 4508422 yjiS 7953712 yjiS Escherichia coli BW2952 hypothetical protein YP_002929228.1 4508258 D 595496 CDS YP_002929229.1 238903433 7953067 complement(4513419..4514465) 1 NC_012759.1 McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity; 5-methylcytosine-specific restriction enzyme subunit McrC 4514465 mcrC 7953067 mcrC Escherichia coli BW2952 5-methylcytosine-specific restriction enzyme subunit McrC YP_002929229.1 4513419 R 595496 CDS YP_002929230.1 238903434 7952373 complement(4514465..4515844) 1 NC_012759.1 McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; 5-methylcytosine-specific restriction enzyme subunit McrB 4515844 mcrB 7952373 mcrB Escherichia coli BW2952 5-methylcytosine-specific restriction enzyme subunit McrB YP_002929230.1 4514465 R 595496 CDS YP_002929231.1 238903435 7952372 complement(4516006..4516347) 1 NC_012759.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 4516347 symE 7952372 symE Escherichia coli BW2952 endoribonuclease SymE YP_002929231.1 4516006 R 595496 CDS YP_002929232.1 238903436 7952202 complement(4516575..4517969) 1 NC_012759.1 specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS 4517969 hsdS 7952202 hsdS Escherichia coli BW2952 EcoKI restriction-modification system protein HsdS YP_002929232.1 4516575 R 595496 CDS YP_002929233.1 238903437 7956060 complement(4517966..4519555) 1 NC_012759.1 MG1655 equivalent: b4349; DNA methylase M 4519555 hsdM 7956060 hsdM Escherichia coli BW2952 DNA methylase M YP_002929233.1 4517966 R 595496 CDS YP_002929234.1 238903438 7953313 complement(4519756..4523322) 1 NC_012759.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R 4523322 hsdR 7953313 hsdR Escherichia coli BW2952 type I restriction enzyme EcoKI subunit R YP_002929234.1 4519756 R 595496 CDS YP_002929235.1 238903439 7953519 4523456..4524370 1 NC_012759.1 MG1655 equivalent: b4351; methylated adenine and cytosine restriction protein 4524370 mrr 7953519 mrr Escherichia coli BW2952 methylated adenine and cytosine restriction protein YP_002929235.1 4523456 D 595496 CDS YP_002929236.1 238903440 7954253 complement(4524416..4525372) 1 NC_012759.1 MG1655 equivalent: b4352; putative GTP-binding protein YjiA 4525372 yjiA 7954253 yjiA Escherichia coli BW2952 putative GTP-binding protein YjiA YP_002929236.1 4524416 R 595496 CDS YP_002929237.1 238903441 7954939 complement(4525383..4525586) 1 NC_012759.1 MG1655 equivalent: b4353; hypothetical protein 4525586 yjiX 7954939 yjiX Escherichia coli BW2952 hypothetical protein YP_002929237.1 4525383 R 595496 CDS YP_002929238.1 238903442 7952904 complement(4525636..4527786) 1 NC_012759.1 MG1655 equivalent: b4354; putative inner membrane protein 4527786 yjiY 7952904 yjiY Escherichia coli BW2952 putative inner membrane protein YP_002929238.1 4525636 R 595496 CDS YP_002929239.1 238903443 7955020 4528164..4529819 1 NC_012759.1 MG1655 equivalent: b4355; methyl-accepting chemotaxis protein I, serine sensor receptor 4529819 tsr 7955020 tsr Escherichia coli BW2952 methyl-accepting chemotaxis protein I, serine sensor receptor YP_002929239.1 4528164 D 595496 CDS YP_002929240.1 238903444 7954248 complement(4529868..4531229) 1 NC_012759.1 MG1655 equivalent: b4356; putative transporter 4531229 yjjL 7954248 yjjL Escherichia coli BW2952 putative transporter YP_002929240.1 4529868 R 595496 CDS YP_002929241.1 238903445 7955676 complement(4531444..4532358) 1 NC_012759.1 MG1655 equivalent: b4357; putative DNA-binding transcriptional regulator 4532358 yjjM 7955676 yjjM Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002929241.1 4531444 R 595496 CDS YP_002929242.1 238903446 7954787 4532506..4533519 1 NC_012759.1 MG1655 equivalent: b4358; putative oxidoreductase, Zn-dependent and NAD(P)-binding 4533519 yjjN 7954787 yjjN Escherichia coli BW2952 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002929242.1 4532506 D 595496 CDS YP_002929243.1 238903447 7955266 complement(4533657..4535948) 1 NC_012759.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4535948 mdoB 7955266 mdoB Escherichia coli BW2952 phosphoglycerol transferase I YP_002929243.1 4533657 R 595496 CDS YP_002929244.1 238903448 7954535 complement(4536202..4536696) 1 NC_012759.1 MG1655 equivalent: b4360; hypothetical protein 4536696 yjjA 7954535 yjjA Escherichia coli BW2952 hypothetical protein YP_002929244.1 4536202 R 595496 CDS YP_002929245.1 238903449 7952905 complement(4536745..4537482) 1 NC_012759.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4537482 dnaC 7952905 dnaC Escherichia coli BW2952 DNA replication protein DnaC YP_002929245.1 4536745 R 595496 CDS YP_002929246.1 238903450 7953300 complement(4537485..4538024) 1 NC_012759.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4538024 dnaT 7953300 dnaT Escherichia coli BW2952 primosomal protein DnaI YP_002929246.1 4537485 R 595496 CDS YP_002929247.1 238903451 7953301 complement(4538131..4538604) 1 NC_012759.1 MG1655 equivalent: b4363; hypothetical protein 4538604 yjjB 7953301 yjjB Escherichia coli BW2952 hypothetical protein YP_002929247.1 4538131 R 595496 CDS YP_002929248.1 238903452 7952697 complement(4538595..4539365) 1 NC_012759.1 MG1655 equivalent: b4364; putative inner membrane protein 4539365 yjjP 7952697 yjjP Escherichia coli BW2952 putative inner membrane protein YP_002929248.1 4538595 R 595496 CDS YP_002929249.1 238903453 7955021 4539984..4540709 1 NC_012759.1 MG1655 equivalent: b4365; putative DNA-binding transcriptional regulator 4540709 yjjQ 7955021 yjjQ Escherichia coli BW2952 putative DNA-binding transcriptional regulator YP_002929249.1 4539984 D 595496 CDS YP_002929250.1 238903454 7954819 4540817..4541344 1 NC_012759.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4541344 bglJ 7954819 bglJ Escherichia coli BW2952 DNA-binding transcriptional activator BglJ YP_002929250.1 4540817 D 595496 CDS YP_002929251.1 238903455 7953384 complement(4541382..4542170) 1 NC_012759.1 MG1655 equivalent: b4367; ferric hydroximate transport ferric iron reductase 4542170 fhuF 7953384 fhuF Escherichia coli BW2952 ferric hydroximate transport ferric iron reductase YP_002929251.1 4541382 R 595496 CDS YP_002929252.1 238903456 7953568 4542311..4542547 1 NC_012759.1 MG1655 equivalent: b4567; hypothetical protein 4542547 yjjZ 7953568 yjjZ Escherichia coli BW2952 hypothetical protein YP_002929252.1 4542311 D 595496 CDS YP_002929253.1 238903457 7952077 complement(4543176..4544207) 1 NC_012759.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4544207 rsmC 7952077 rsmC Escherichia coli BW2952 16S ribosomal RNA m2G1207 methyltransferase YP_002929253.1 4543176 R 595496 CDS YP_002929254.1 238903458 7952222 4544310..4544723 1 NC_012759.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4544723 holD 7952222 holD Escherichia coli BW2952 DNA polymerase III subunit psi YP_002929254.1 4544310 D 595496 CDS YP_002929255.1 238903459 7953324 4544692..4545138 1 NC_012759.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4545138 rimI 7953324 rimI Escherichia coli BW2952 ribosomal-protein-alanine N-acetyltransferase YP_002929255.1 4544692 D 595496 CDS YP_002929256.1 238903460 7952397 4545153..4545830 1 NC_012759.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4545830 yjjG 7952397 yjjG Escherichia coli BW2952 nucleotidase YP_002929256.1 4545153 D 595496 CDS YP_002929257.1 238903461 7953506 4545921..4547510 1 NC_012759.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4547510 prfC 7953506 prfC Escherichia coli BW2952 peptide chain release factor 3 YP_002929257.1 4545921 D 595496 CDS YP_002929258.1 238903462 7954476 4547903..4548508 1 NC_012759.1 MG1655 equivalent: b4376; hypothetical protein 4548508 osmY 7954476 osmY Escherichia coli BW2952 hypothetical protein YP_002929258.1 4547903 D 595496 CDS YP_002929259.1 238903463 7954497 4548635..4548796 1 NC_012759.1 MG1655 equivalent: b4568; hypothetical protein 4548796 ytjA 7954497 ytjA Escherichia coli BW2952 hypothetical protein YP_002929259.1 4548635 D 595496 CDS YP_002929260.1 238903464 7955541 4548918..4549991 1 NC_012759.1 MG1655 equivalent: b4377; putative esterase 4549991 yjjU 7955541 yjjU Escherichia coli BW2952 putative esterase YP_002929260.1 4548918 D 595496 CDS YP_002929261.1 238903465 7954864 4549988..4550767 1 NC_012759.1 MG1655 equivalent: b4378; putative deoxyribonuclease YjjV 4550767 yjjV 7954864 yjjV Escherichia coli BW2952 putative deoxyribonuclease YjjV YP_002929261.1 4549988 D 595496 CDS YP_002929262.1 238903466 7954826 complement(4551187..4552050) 1 NC_012759.1 MG1655 equivalent: b4379; putative pyruvate formate lyase activating enzyme 4552050 yjjW 7954826 yjjW Escherichia coli BW2952 putative pyruvate formate lyase activating enzyme YP_002929262.1 4551187 R 595496 CDS YP_002929263.1 238903467 7955552 complement(4552022..4553572) 1 NC_012759.1 MG1655 equivalent: b4380; hypothetical protein 4553572 yjjI 7955552 yjjI Escherichia coli BW2952 hypothetical protein YP_002929263.1 4552022 R 595496 CDS YP_002929264.1 238903468 7952906 4553830..4554609 1 NC_012759.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4554609 deoC 7952906 deoC Escherichia coli BW2952 deoxyribose-phosphate aldolase YP_002929264.1 4553830 D 595496 CDS YP_002929265.1 238903469 7952258 4554736..4556058 1 NC_012759.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4556058 deoA 7952258 deoA Escherichia coli BW2952 thymidine phosphorylase YP_002929265.1 4554736 D 595496 CDS YP_002929266.1 238903470 7956149 4556110..4557333 1 NC_012759.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4557333 deoB 7956149 deoB Escherichia coli BW2952 phosphopentomutase YP_002929266.1 4556110 D 595496 CDS YP_002929267.1 238903471 7954547 4557390..4558109 1 NC_012759.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4558109 deoD 7954547 deoD Escherichia coli BW2952 purine nucleoside phosphorylase YP_002929267.1 4557390 D 595496 CDS YP_002929268.1 238903472 7955825 4558276..4559607 1 NC_012759.1 MG1655 equivalent: b4385; hypothetical protein 4559607 yjjJ 7955825 yjjJ Escherichia coli BW2952 hypothetical protein YP_002929268.1 4558276 D 595496 CDS YP_002929269.1 238903473 7954820 complement(4559608..4560624) 1 NC_012759.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4560624 lplA 7954820 lplA Escherichia coli BW2952 lipoate-protein ligase A YP_002929269.1 4559608 R 595496 CDS YP_002929270.1 238903474 7954148 complement(4560652..4561296) 1 NC_012759.1 MG1655 equivalent: b4387; hypothetical protein 4561296 ytjB 7954148 ytjB Escherichia coli BW2952 hypothetical protein YP_002929270.1 4560652 R 595496 CDS YP_002929271.1 238903475 7952907 4561402..4562370 1 NC_012759.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4562370 serB 7952907 serB Escherichia coli BW2952 phosphoserine phosphatase YP_002929271.1 4561402 D 595496 CDS YP_002929272.1 238903476 7952325 4562419..4563801 1 NC_012759.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4563801 radA 7952325 radA Escherichia coli BW2952 DNA repair protein RadA YP_002929272.1 4562419 D 595496 CDS YP_002929273.1 238903477 7955566 4563822..4565054 1 NC_012759.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4565054 nadR 7955566 nadR Escherichia coli BW2952 nicotinamide-nucleotide adenylyltransferase YP_002929273.1 4563822 D 595496 CDS YP_002929274.1 238903478 7952566 complement(4565362..4567029) 1 NC_012759.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 4567029 yjjK 7952566 yjjK Escherichia coli BW2952 putative ABC transporter ATP-binding protein YP_002929274.1 4565362 R 595496 CDS YP_002929275.1 238903479 7953731 4567240..4569177 1 NC_012759.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4569177 slt 7953731 slt Escherichia coli BW2952 lytic murein transglycosylase YP_002929275.1 4567240 D 595496 CDS YP_002929276.1 238903480 7954189 4569267..4569593 1 NC_012759.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4569593 trpR 7954189 trpR Escherichia coli BW2952 Trp operon repressor YP_002929276.1 4569267 D 595496 CDS YP_002929277.1 238903481 7953482 complement(4569740..4570252) 1 NC_012759.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4570252 yjjX 7953482 yjjX Escherichia coli BW2952 NTPase YP_002929277.1 4569740 R 595496 CDS YP_002929278.1 238903482 7956127 4570304..4570951 1 NC_012759.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4570951 ytjC 7956127 ytjC Escherichia coli BW2952 phosphoglycerate mutase YP_002929278.1 4570304 D 595496 CDS YP_002929279.1 238903483 7954537 complement(4570948..4571817) 1 NC_012759.1 MG1655 equivalent: b4396; DNA-binding transcriptional activator 4571817 rob 7954537 rob Escherichia coli BW2952 DNA-binding transcriptional activator YP_002929279.1 4570948 R 595496 CDS YP_002929280.1 238903484 7953374 4572028..4572501 1 NC_012759.1 MG1655 equivalent: b4397; hypothetical protein 4572501 creA 7953374 creA Escherichia coli BW2952 hypothetical protein YP_002929280.1 4572028 D 595496 CDS YP_002929281.1 238903485 7953068 4572514..4573203 1 NC_012759.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4573203 creB 7953068 creB Escherichia coli BW2952 DNA-binding response regulator CreB YP_002929281.1 4572514 D 595496 CDS YP_002929282.1 238903486 7953349 4573203..4574627 1 NC_012759.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4574627 creC 7953349 creC Escherichia coli BW2952 sensory histidine kinase CreC YP_002929282.1 4573203 D 595496 CDS YP_002929283.1 238903487 7956016 4574685..4576037 1 NC_012759.1 MG1655 equivalent: b4400; hypothetical protein 4576037 creD 7956016 creD Escherichia coli BW2952 hypothetical protein YP_002929283.1 4574685 D 595496 CDS YP_002929284.1 238903488 7953998 complement(4576097..4576813) 1 NC_012759.1 MG1655 equivalent: b4401; two-component response regulator 4576813 arcA 7953998 arcA Escherichia coli BW2952 two-component response regulator YP_002929284.1 4576097 R 595496 CDS YP_002929285.1 238903489 7953343 4576909..4577049 1 NC_012759.1 MG1655 equivalent: b4402; hypothetical protein 4577049 yjjY 7953343 yjjY Escherichia coli BW2952 hypothetical protein YP_002929285.1 4576909 D 595496 CDS YP_002929286.1 238903490 7955526 4577449..4578135 1 NC_012759.1 member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 4578135 yjtD 7955526 yjtD Escherichia coli BW2952 putative RNA methyltransferase YP_002929286.1 4577449 D 595496 CDS